Rhodospirillum rubrum ATCC 11170, complete genome NC_007643 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 83592915 Common - GCN5-related N-acetyltransferase Rru_A1580 15 COG0456 RimI, Acetyltransferases General function prediction only 83592274 Common - Glycosyl transferase, family 2 Rru_A0938 204 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83594320 Common - precorrin-2 C(20)-methyltransferase Rru_A2990 153 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 83591460 Common - chemotaxis sensory transducer Rru_A0120 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83591609 Nonpathogen - hypothetical protein Rru_A0269 1 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83595104 Common - Transcriptional Regulator, XRE family Rru_A3775 39 COG1396 HipB, Predicted transcriptional regulators Transcription 83592483 Common - Acetylornithine and succinylornithine aminotransferase Rru_A1147 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 83593982 Nonpathogen - hypothetical protein Rru_A2650 1 None None None 83592064 Common - Cyclopropane-fatty-acyl-phospholipid synthase Rru_A0725 138 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 83593450 Common - phosphoglucomutase Rru_A2115 195 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 83594043 Common - GCN5-related N-acetyltransferase Rru_A2711 28 COG0456 RimI, Acetyltransferases General function prediction only 83591518 Common - CRISPR-associated protein Cas2, putative Rru_A0178 12 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83593417 Common - Hemerythrin HHE cation binding region Rru_A2082 45 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 83592250 Common - Aldehyde dehydrogenase Rru_A0914 205 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83594408 Common - Electron transfer flavoprotein Rru_A3078 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 83593115 Common - Deoxyguanosinetriphosphate triphosphohydrolase Rru_A1780 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 83592927 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Rru_A1592 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 83593025 Common - MazG Rru_A1690 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 83591782 Common - FAD linked oxidase-like Rru_A0442 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83594936 Common - murein degrading transglycosylase protein Rru_A3607 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 83592339 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Rru_A1003 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83592497 Common - Ni-Fe hydrogenase, small subunit Rru_A1161 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 83591381 Common - Cytochrome c, class II Rru_A0041 12 COG3909 COG3909, Cytochrome c556 Energy production and conversion 83593194 Common - Protein of unknown function DUF88 Rru_A1859 61 COG1432 COG1432, Uncharacterized conserved protein Function unknown 83594371 Common - regulatory protein GntR Rru_A3041 178 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83594466 Common - putative partition-related protein Rru_A3136 69 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83594107 Common - Dienelactone hydrolase Rru_A2775 57 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 83592734 Common - Response regulator receiver domain protein (CheY) Rru_A1398 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83594113 Common - hypothetical protein Rru_A2781 29 COG5441 COG5441, Uncharacterized conserved protein Function unknown 83592559 Common - H+-transporting two-sector ATPase, delta (OSCP) subunit Rru_A1223 110 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 83595032 Common - ABC-3 transporter component Rru_A3703 156 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 83591833 Common - Phytoene desaturase Rru_A0493 97 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83591996 Common - Lysine exporter protein (LYSE/YGGA) Rru_A0657 78 COG1279 COG1279, Lysine efflux permease General function prediction only 83594732 Common - Sulphate transport system permease protein 1 Rru_A3403 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 83592909 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Rru_A1574 59 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 83593749 Nonpathogen - hypothetical protein Rru_A2414 1 None None None 83594618 Common - Signal Transduction Histidine Kinase Rru_A3288 101 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 83594021 Common rpsJ 30S ribosomal protein S10 Rru_A2689 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 83592861 Common - Cobyrinic acid a,c-diamide synthase Rru_A1526 156 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83592223 Common - Secretion protein HlyD Rru_A0887 137 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83593561 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Rru_A2226 210 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83592878 Common - Putative molybdenum utilization protein ModD Rru_A1543 97 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 83594436 Nonpathogen - hypothetical protein Rru_A3106 1 COG5652 COG5652, Predicted integral membrane protein Function unknown 83594401 Common - Protein of unknown function DUF6, transmembrane Rru_A3071 21 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83593463 Common - Transcriptional Regulator, LytR/AlgR family Rru_A2128 12 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 83591849 Nonpathogen - hypothetical protein Rru_A0510 5 None None None 83593959 Common - pyridoxamine 5'-phosphate oxidase Rru_A2627 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 83592775 Common - Putative FecR Rru_A1439 47 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 83593357 Nonpathogen - hypothetical protein Rru_A2022 1 None None None 83592416 Common - Thiamine-phosphate diphosphorylase Rru_A1080 202 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 83594390 Nonpathogen - hypothetical protein Rru_A3060 1 None None None 83591840 Common - extracellular solute-binding protein, family 1 Rru_A0500 66 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 83593112 Common - Beta-N-acetylhexosaminidase Rru_A1777 169 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 83592159 Common - hypothetical protein Rru_A0822 14 None None None 83594852 Common - Phenylalanyl-tRNA synthetase, alpha subunit Rru_A3523 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 83594327 Common - phosphate acetyltransferase Rru_A2997 179 COG0280 Pta, Phosphotransacetylase Energy production and conversion 83592841 Common - Allophanate hydrolase subunit 2 Rru_A1505 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 83593186 Common era GTP-binding protein Era Rru_A1851 234 COG1159 Era, GTPase General function prediction only 83593048 Common - NAD(P)H dehydrogenase (quinone) Rru_A1713 96 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 83592281 Common - Cell division protein FtsA Rru_A0945 179 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 83594972 Common - GrpE protein Rru_A3643 221 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 83592345 Nonpathogen - NAD(+)--dinitrogen-reductase ADP-D-ribosyltransferase Rru_A1009 11 None None None 83593541 Common - tartrate dehydrogenase Rru_A2206 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 83593149 Common - Carbon monoxide dehydrogenase subunit G Rru_A1814 32 COG3427 COG3427, Uncharacterized conserved protein Function unknown 83592755 Common - Carboxylyase-related protein Rru_A1419 153 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 83594138 Common - Protein of unknown function DUF214 Rru_A2806 22 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 83594384 Common - Ribonuclease H Rru_A3054 178 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 83594051 Common - Indolepyruvate decarboxylase Rru_A2719 221 COG3961 COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only 83593672 Common - TonB-dependent receptor Rru_A2337 105 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 83593568 Common - transcriptional regulatory protein Rru_A2233 10 COG1846 MarR, Transcriptional regulators Transcription 83591501 Common - Chaperonin Cpn10 Rru_A0161 214 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 83591350 Common - RNA polymerase factor sigma-54 Rru_A0010 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 83591900 Common - Cytochrome bd ubiquinol oxidase, subunit II Rru_A0561 147 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 83593423 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Rru_A2088 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83591479 Common - Transcriptional Regulator, MarR family Rru_A0139 21 COG1846 MarR, Transcriptional regulators Transcription 83593341 Common - L-carnitine dehydratase/bile acid-inducible protein F Rru_A2006 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 83593717 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2382 99 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 83593499 Common - hypothetical protein Rru_A2164 145 COG0628 PerM, Predicted permease General function prediction only 83593273 Common - Protein of unknown function DUF519 Rru_A1938 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 83593453 Common - ATPase Rru_A2118 79 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83593973 Common - hypothetical protein Rru_A2641 14 COG4627 COG4627, Uncharacterized protein conserved in bacteria Function unknown 83592323 Common - Glutathione S-transferase-like Rru_A0987 46 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83592995 Common - Peptidase M23B Rru_A1660 114 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83592185 Nonpathogen - hypothetical protein Rru_A0849 1 None None None 83591595 Nonpathogen - hypothetical protein Rru_A0255 2 None None None 83594376 Common - Radical SAM Rru_A3046 32 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 83591470 Common - chemotaxis sensory transducer Rru_A0130 98 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593151 Common - Poly(R)-hydroxyalkanoic acid synthase, class I Rru_A1816 74 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 83594353 Nonpathogen - hypothetical protein Rru_A3023 1 None None None 83592592 Nonpathogen - hypothetical protein Rru_A1256 1 None None None 83593725 Common - Twin-arginine translocation pathway signal Rru_A2390 132 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 83592728 Common - Nitrogenase Rru_A1392 52 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83592407 Common - Adenylate/Guanylate Cyclase Rru_A1071 40 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 83594467 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Rru_A3137 193 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83593297 Common - hypothetical protein Rru_A1962 36 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83593891 Common - Mandelate racemase/muconate lactonizing enzyme Rru_A2556 107 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 83593812 Common proX glycine betaine transporter periplasmic subunit Rru_A2477 44 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 83594057 Common - Multi-sensor Hybrid Histidine Kinase Rru_A2725 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83592575 Common - gamma-glutamyl kinase Rru_A1239 192 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 83592747 Common - Protein of unknown function DUF162 Rru_A1411 65 COG1556 COG1556, Uncharacterized conserved protein Function unknown 83594451 Common - Asparagine synthase, glutamine-hydrolyzing Rru_A3121 154 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83594739 Common - Protein of unknown function DUF891 Rru_A3410 26 COG4679 COG4679, Phage-related protein Function unknown 83593142 Common - OmpA/MotB Rru_A1807 137 COG1360 MotB, Flagellar motor protein Cell motility and secretion 83594677 Common - Protein of unknown function DUF195 Rru_A3348 143 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 83592367 Common - ethanolamine ammonia-lyase small subunit Rru_A1031 51 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 83594545 Common - hypothetical protein Rru_A3215 7 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 83592236 Common - hypothetical protein Rru_A0900 19 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 83595078 Common - hypothetical protein Rru_A3749 48 COG4637 COG4637, Predicted ATPase General function prediction only 83592570 Common - phosphoglyceromutase Rru_A1234 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 83592827 Nonpathogen - hypothetical protein Rru_A1491 1 None None None 83593265 Common - hypothetical protein Rru_A1930 52 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 83592691 Common - Protein of unknown function DUF892 Rru_A1355 21 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 83594824 Nonpathogen - hypothetical protein Rru_A3495 1 None None None 83593440 Common - inner-membrane translocator Rru_A2105 51 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 83591890 Common - TPR domain protein Rru_A0551 31 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 83594220 Common - hypothetical protein Rru_A2888 4 None None None 83591716 Common - putative two-component response-regulatory protein YehT Rru_A0376 183 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 83594185 Common - hypothetical protein Rru_A2853 11 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 83592112 Common - Nitrogenase Rru_A0773 58 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83593257 Common - DSBA oxidoreductase Rru_A1922 81 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 83594873 Common - Phosphate uptake regulator, PhoU Rru_A3544 198 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 83592738 Common - CheW protein Rru_A1402 125 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83592510 Common - Endoribonuclease L-PSP Rru_A1174 145 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 83592045 Common - RarD protein Rru_A0706 95 COG2962 RarD, Predicted permeases General function prediction only 83592547 Common - Succinyl-CoA synthetase, beta subunit Rru_A1211 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 83594202 Common - integral membrane protein TerC Rru_A2870 218 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 83593100 Common - YajC Rru_A1765 143 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 83593485 Nonpathogen - hypothetical protein Rru_A2150 1 None None None 83591487 Common - Major facilitator superfamily MFS_1 Rru_A0147 95 None None None 83594802 Common - DNA polymerase III subunits gamma and tau Rru_A3473 246 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 83592622 Common - hypothetical protein Rru_A1286 8 None None None 83594123 Common - DeoxyUTP pyrophosphatase subfamily 1 Rru_A2791 178 COG0756 Dut, dUTPase Nucleotide transport and metabolism 83591728 Common - Protein of unknown function DUF6, transmembrane Rru_A0388 75 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83594850 Common - Ribosomal protein L35 Rru_A3521 161 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 83594209 Common - threonine dehydratase Rru_A2877 207 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 83594673 Common - Transcriptional Regulator, XRE family Rru_A3344 32 COG1476 COG1476, Predicted transcriptional regulators Transcription 83592674 Common - inner-membrane translocator Rru_A1338 111 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 83594566 Common - hypothetical protein Rru_A3236 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83592533 Common - chemotaxis sensory transducer Rru_A1197 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83591685 Common - CRISPR-associated CT1976 family protein Rru_A0345 7 None None None 83593401 Common - Dihydrodipicolinate synthetase Rru_A2066 230 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 83591976 Nonpathogen - hypothetical protein Rru_A0637 1 None None None 83591943 Nonpathogen - hypothetical protein Rru_A0604 1 None None None 83591419 Common - Transcriptional Regulator, CarD family Rru_A0079 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 83592791 Common - Phage Tail Collar Rru_A1455 37 COG4675 MdpB, Microcystin-dependent protein Function unknown 83591639 Common - Glutamine amidotransferase class-I Rru_A0299 134 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 83591467 Common - ABC-2 transporter component Rru_A0127 32 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 83594637 Common - inner-membrane translocator Rru_A3307 144 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 83593176 Common - Flavin reductase-like, FMN-binding Rru_A1841 117 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 83592531 Common - Cell wall hydrolase, SleB Rru_A1195 44 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 83592229 Common - stress protein Rru_A0893 28 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 83594768 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Rru_A3439 234 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 83594684 Common - hypothetical protein Rru_A3355 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 83592094 Common - chemotaxis sensory transducer Rru_A0755 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593992 Common - recombination factor protein RarA Rru_A2660 203 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 83593593 Nonpathogen - hypothetical protein Rru_A2258 2 COG4575 ElaB, Uncharacterized conserved protein Function unknown 83593497 Common - Phosphohistidine Phosphatase, SixA Rru_A2162 64 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 83593773 Common - Mammalian cell entry related Rru_A2438 98 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 83592051 Nonpathogen - Transcriptional Regulator, XRE family Rru_A0712 1 COG1396 HipB, Predicted transcriptional regulators Transcription 83594635 Common - ABC transporter component Rru_A3305 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83592506 Common - Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family Rru_A1170 171 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83593967 Common - Transcriptional Regulator, Crp/Fnr family Rru_A2635 45 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83595006 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Rru_A3677 51 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 83594575 Nonpathogen - H+-transporting two-sector ATPase, C subunit Rru_A3245 2 None None None 83594367 Common - chemotaxis sensory transducer Rru_A3037 102 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592580 Nonpathogen - hypothetical protein Rru_A1244 1 None None None 83592858 Common - Hemerythrin Rru_A1523 2 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 83593787 Nonpathogen - hypothetical protein Rru_A2452 6 COG2378 COG2378, Predicted transcriptional regulator Transcription 83591702 Common - Cytochrome c1 Rru_A0362 57 COG2857 CYT1, Cytochrome c1 Energy production and conversion 83592684 Common - Protein of unknown function DUF81 Rru_A1348 132 COG0730 COG0730, Predicted permeases General function prediction only 83595047 Nonpathogen - hypothetical protein Rru_A3718 3 None None None 83594338 Common - hypothetical protein Rru_A3008 20 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 83594662 Common - hypothetical protein Rru_A3333 109 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 83593537 Common - HflC Rru_A2202 203 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 83592886 Common clpX ATP-dependent protease ATP-binding subunit Rru_A1551 224 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 83593642 Common - Twin-arginine translocation pathway signal Rru_A2307 97 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 83594814 Nonpathogen - hypothetical protein Rru_A3485 1 None None None 83593894 Common - hypothetical protein Rru_A2559 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 83594487 Common - hypothetical protein Rru_A3157 37 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 83591641 Common - Alkylhydroperoxidase AhpD core Rru_A0301 32 COG2128 COG2128, Uncharacterized conserved protein Function unknown 83593396 Common - hypothetical protein Rru_A2061 5 None None None 83593802 Common - Ribosomal protein L36 Rru_A2467 74 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 83593054 Common - Thioesterase superfamily Rru_A1719 113 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 83591815 Common - NADH:flavin oxidoreductase/NADH oxidase Rru_A0475 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 83594242 Common - Mammalian cell entry related Rru_A2910 15 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 83594429 Nonpathogen - hypothetical protein Rru_A3099 1 None None None 83591749 Common - Alanine racemase region Rru_A0409 198 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 83592835 Common - Ferritin and Dps Rru_A1499 17 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 83594416 Common - hypothetical protein Rru_A3086 7 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 83591602 Common - chemotaxis sensory transducer Rru_A0262 111 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593271 Common - ErfK/YbiS/YcfS/YnhG Rru_A1936 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 83594506 Common - Glutamyl-tRNA(Gln) amidotransferase A subunit Rru_A3176 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 83593655 Common - Ankyrin Rru_A2320 130 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 83592169 Common - Protein of unknown function DUF48 Rru_A0833 103 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83592733 Nonpathogen - Sulfate transporter/antisigma-factor antagonist STAS Rru_A1397 3 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 83592780 Common - ribonucleotide-diphosphate reductase subunit alpha Rru_A1444 221 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 83591493 Common - Endonuclease III/Nth Rru_A0153 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 83592723 Common - hypothetical protein Rru_A1387 38 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 83591876 Common - Protein of unknown function DUF955 Rru_A0537 22 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 83591409 Common - ABC transporter component Rru_A0069 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83592955 Common - hypothetical protein Rru_A1620 28 COG4704 COG4704, Uncharacterized protein conserved in bacteria Function unknown 83591916 Common - hypothetical protein Rru_A0577 102 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 83592084 Common - PTSINtr with GAF domain, PtsP Rru_A0745 217 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 83593652 Common - pyruvate carboxylase Rru_A2317 240 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 83594076 Common - hypothetical protein Rru_A2744 36 None None None 83594861 Common - UspA Rru_A3532 26 None None None 83593092 Common - tRNA (uracil-5-)-methyltransferase Gid Rru_A1757 145 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 83591581 Common - DNA methylase N-4/N-6 Rru_A0241 106 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 83593871 Nonpathogen - hypothetical protein Rru_A2536 2 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 83593067 Nonpathogen - hypothetical protein Rru_A1732 1 None None None 83594505 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Rru_A3175 211 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 83594047 Common - Acyltransferase 3 Rru_A2715 13 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 83592162 Nonpathogen - hypothetical protein Rru_A0826 5 None None None 83592138 Common - extracellular solute-binding protein, family 5 Rru_A0799 196 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 83592661 Common - hypothetical protein Rru_A1325 35 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 83593612 Common - Nickel ABC transporter, periplasmic nickel-binding Rru_A2277 199 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 83593047 Common - chemotaxis sensory transducer Rru_A1712 164 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592630 Common - Transcriptional Regulator, Histidine utilization repressor, GntR family Rru_A1294 126 COG2188 PhnF, Transcriptional regulators Transcription 83594231 Common - Transcriptional Regulator, LysR family Rru_A2899 186 COG0583 LysR, Transcriptional regulator Transcription 83593375 Common - Peptide chain release factor 2 Rru_A2040 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 83591395 Common - VacJ-like lipoprotein Rru_A0055 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 83594440 Common - Cyclic nucleotide-binding domain (cNMP-BD) protein Rru_A3110 133 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 83593827 Common - Glycosyl transferase, group 1 Rru_A2492 212 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83591899 Common - Cytochrome bd ubiquinol oxidase, subunit I Rru_A0560 162 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 83593998 Common rpsM 30S ribosomal protein S13 Rru_A2666 244 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 83591374 Common - Periplasmic protein thiol-disulfide oxidoreductase DsbE Rru_A0034 111 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 83591658 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A0318 189 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 83592967 Common - putative monovalent cation/H+ antiporter subunit D Rru_A1632 209 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 83593479 Common - hypothetical protein Rru_A2144 18 COG3811 COG3811, Uncharacterized protein conserved in bacteria Function unknown 83592504 Common - Hydrogenase expression/synthesis, HypA Rru_A1168 98 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 83594599 Common - hypothetical protein Rru_A3269 46 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83592392 Common - Zinc-containing alcohol dehydrogenase superfamily Rru_A1056 186 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83593321 Common - Protein of unknown function DUF1526 Rru_A1986 26 None None None 83595129 Nonpathogen - hypothetical protein Rru_A3800 3 None None None 83593531 Common - BFD-like (2Fe-2S)-binding region Rru_A2196 12 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 83592218 Common - ABC transporter, transmembrane region Rru_A0882 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83594345 Common - Twin-arginine translocation pathway signal Rru_A3015 7 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 83593639 Common - Transcriptional Regulator, DeoR family Rru_A2304 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 83592897 Common - Respiratory-chain NADH dehydrogenase, subunit 1 Rru_A1562 192 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 83594175 Common flgG flagellar basal body rod protein FlgG Rru_A2843 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 83592971 Common - NADH-ubiquinone oxidoreductase, chain 4L Rru_A1636 82 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 83592085 Common - hypothetical protein Rru_A0746 45 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 83593820 Common - Alpha,alpha-trehalose-phosphate synthase (UDP-forming) Rru_A2485 96 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 83595121 Nonpathogen - hypothetical protein Rru_A3792 2 COG2210 COG2210, Uncharacterized conserved protein Function unknown 83594399 Common - Plasmid maintenance system killer Rru_A3069 57 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 83591764 Nonpathogen - hypothetical protein Rru_A0424 1 None None None 83593705 Common - GCN5-related N-acetyltransferase Rru_A2370 32 COG3153 COG3153, Predicted acetyltransferase General function prediction only 83593086 Common - inner-membrane translocator Rru_A1751 150 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 83593712 Common - Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Rru_A2377 11 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 83594897 Common - Porphobilinogen deaminase Rru_A3568 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 83593472 Common - Protein of unknown function DUF847 Rru_A2137 19 COG3926 zliS, Putative secretion activating protein General function prediction only 83593246 Common - Ferric uptake regulator (FUR) family Rru_A1911 80 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 83593944 Common - UspA Rru_A2612 57 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 83592977 Common - putative sulfonate/nitrate transport system substrate-binding protein Rru_A1642 108 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 83591529 Common - ABC transporter, transmembrane region Rru_A0189 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83591757 Common - Acyl carrier protein (ACP) Rru_A0417 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 161777627 Common - hypothetical protein Rru_A1086 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 83592176 Common - Major facilitator superfamily MFS_1 Rru_A0840 23 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83594616 Nonpathogen - hypothetical protein Rru_A3286 1 None None None 83593438 Common - L-carnitine dehydratase/bile acid-inducible protein F Rru_A2103 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 83594767 Common - hypothetical protein Rru_A3438 194 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 83593200 Common - Dihydrodipicolinate synthase subfamily Rru_A1865 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 83594039 Common - Alpha/beta hydrolase fold Rru_A2707 170 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83591986 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Rru_A0647 210 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 83594153 Common flhB flagellar biosynthesis protein FlhB Rru_A2821 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 83594991 Nonpathogen - hypothetical protein Rru_A3662 2 None None None 83594970 Common - Ribonuclease PH Rru_A3641 182 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 83592318 Common - ABC transporter component Rru_A0982 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 83595039 Common - Peptidase S16, lon-like Rru_A3710 39 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 83594140 Common - periplasmic protein-probably involved in high-affinity Fe2+ transport Rru_A2808 25 COG3470 Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport Inorganic ion transport and metabolism 83595131 Common - Ribosomal protein S20p Rru_A3802 186 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 83594299 Common - alanyl-tRNA synthetase related protein Rru_A2969 150 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 83594331 Common - Carbon starvation protein CstA Rru_A3001 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 83593006 Common - hypothetical protein Rru_A1671 15 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 83594563 Common - Threonine synthase Rru_A3233 163 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 83591969 Nonpathogen - hypothetical protein Rru_A0630 6 None None None 83593914 Nonpathogen - hypothetical protein Rru_A2582 1 None None None 83592680 Common - Transcriptional Regulator, IclR family Rru_A1344 105 COG1414 IclR, Transcriptional regulator Transcription 83592136 Common - major facilitator transporter superfamily MFS_1 Rru_A0797 110 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83594285 Nonpathogen - hypothetical protein Rru_A2953 1 None None None 83591831 Common - ABC transporter component Rru_A0491 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 83593171 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Rru_A1836 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 83592764 Common - Cobyrinic acid a,c-diamide synthase Rru_A1428 54 COG3640 CooC, CO dehydrogenase maturation factor Cell division and chromosome partitioning 83592073 Common - hypothetical protein Rru_A0734 31 COG5496 COG5496, Predicted thioesterase General function prediction only 83594271 Common - hypothetical protein Rru_A2939 25 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83595028 Common - Acriflavin resistance protein Rru_A3699 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83593510 Common - Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like Rru_A2175 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83592039 Nonpathogen - Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Rru_A0700 1 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 83591527 Common - hypothetical protein Rru_A0187 13 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 83594998 Common - hypothetical protein Rru_A3669 55 COG2862 COG2862, Predicted membrane protein Function unknown 83592585 Common - kinase-like Rru_A1249 28 COG0645 COG0645, Predicted kinase General function prediction only 83593746 Common - aminotransferase Rru_A2411 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83592020 Nonpathogen - hypothetical protein Rru_A0681 1 None None None 83593681 Common - hypothetical protein Rru_A2346 16 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 83591897 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Rru_A0558 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83595024 Common - acetyl-CoA synthetase Rru_A3695 196 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 83591918 Common - Glycosyl transferase, group 1 Rru_A0579 171 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83594518 Common - Histidine Kinase Rru_A3188 180 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83592429 Common - hypothetical protein Rru_A1093 9 COG5373 COG5373, Predicted membrane protein Function unknown 83592010 Common - cobalamin synthesis CobW protein Rru_A0671 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 83594958 Common holA DNA polymerase III subunit delta Rru_A3629 41 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 83594759 Common - Acetyl-CoA carboxylase carboxyl transferase, beta subunit Rru_A3430 217 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 83594169 Common - Response regulator receiver domain protein (CheY) Rru_A2837 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83591932 Common - putative sulfite oxidase subunit YedY Rru_A0593 126 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 83593173 Common - Alpha/beta hydrolase fold Rru_A1838 83 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83594186 Common - hypothetical protein Rru_A2854 29 COG0457 NrfG, FOG: TPR repeat General function prediction only 83592210 Nonpathogen - hypothetical protein Rru_A0874 1 None None None 83592061 Common - RNA polymerase sigma factor RpoE Rru_A0722 154 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83593979 Common - hypothetical protein Rru_A2647 14 None None None 83595117 Common - Ferric uptake regulator (FUR) family Rru_A3788 156 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 83592066 Common - hypothetical protein Rru_A0727 36 None None None 83592624 Common - Molybdenum cofactor synthesis protein Rru_A1288 196 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 83594761 Common - hypothetical protein Rru_A3432 12 COG0500 SmtA, SAM-dependent methyltransferases Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83591425 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A0085 213 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83594199 Common - ornithine cyclodeaminase Rru_A2867 89 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 83593636 Common - ABC transporter component Rru_A2301 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 83594915 Common - Peptidoglycan-binding LysM Rru_A3586 54 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 83594961 Common - hypothetical protein Rru_A3632 24 None None None 83594439 Common - Aspartate racemase Rru_A3109 218 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83592005 Common - Multi-sensor Signal Transduction Histidine Kinase Rru_A0666 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83591664 Common - Formate dehydrogenase, alpha subunit Rru_A0324 197 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 83593813 Common - arginine/ornithine transport system ATPase Rru_A2478 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 83592330 Common - Nitrogenase cofactor biosynthesis protein NifB Rru_A0994 68 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 83592007 Common - Cobalamin-5-phosphate synthase CobS Rru_A0668 68 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 83593836 Common - conserved hypothetical cytosolic protein Rru_A2501 26 None None None 83594951 Common - Protein of unknown function DUF255 Rru_A3622 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 83594278 Common mutL DNA mismatch repair protein Rru_A2946 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 83593314 Common - tryptophan synthase subunit beta Rru_A1979 224 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 83594747 Common - Transcriptional Regulator, TetR family Rru_A3418 41 COG1309 AcrR, Transcriptional regulator Transcription 83592863 Common - Toluene tolerance Rru_A1528 33 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 83593831 Nonpathogen - Polysaccharide biosynthesis protein Rru_A2496 3 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 83593131 Common valS valyl-tRNA synthetase Rru_A1796 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83592618 Common - Two component Transcriptional regulator, Winged helix family Rru_A1282 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83593951 Common - 1-deoxy-D-xylulose-5-phosphate synthase Rru_A2619 224 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 83591449 Common - type II and III secretion system protein Rru_A0109 130 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 83592610 Common - Radical SAM Rru_A1274 74 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 83594779 Common - Ribonuclease T2 Rru_A3450 20 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 83591583 Common - tRNA/rRNA cytosine-C5-methylase Rru_A0243 206 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 83592450 Common - Major facilitator superfamily MFS_1 Rru_A1114 176 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83591962 Common - light-independent protochlorophyllide reductase subunit N Rru_A0623 26 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83593079 Common - DNA gyrase, subunit A Rru_A1744 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 83593843 Common - 5-aminolevulinate synthase Rru_A2508 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 83592663 Common - hypothetical protein Rru_A1327 4 None None None 83594770 Common - Transcriptional Regulator, PadR-like family Rru_A3441 73 COG1695 COG1695, Predicted transcriptional regulators Transcription 83594573 Common - H+-transporting two-sector ATPase, B/B' subunit Rru_A3243 96 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 83594794 Common - chemotaxis sensory transducer Rru_A3465 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83595092 Common - Peptidase M22, glycoprotease Rru_A3763 178 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 83591817 Nonpathogen - hypothetical protein Rru_A0477 1 None None None 83591867 Common - Heat shock protein DnaJ-like Rru_A0528 206 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 83592638 Common - N-formimino-L-glutamate deiminase Rru_A1302 98 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 83592243 Common - microcompartments protein Rru_A0907 3 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 83593217 Common - Septum formation initiator Rru_A1882 8 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 83592129 Common - Phenylacetate--CoA ligase Rru_A0790 122 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 83592171 Nonpathogen - hypothetical protein Rru_A0835 3 None None None 83594315 Nonpathogen - Hydroxyneurosporene synthase Rru_A2985 11 COG5621 COG5621, Predicted secreted hydrolase General function prediction only 83593368 Common - PAS/PAC Sensor Hybrid Histidine Kinase Rru_A2033 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83594750 Common - Protein of unknown function DUF461 Rru_A3421 86 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 83594921 Common - Histidine triad (HIT) protein Rru_A3592 211 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 83594223 Common - hypothetical protein Rru_A2891 26 None None None 83592943 Common - MscS Mechanosensitive ion channel Rru_A1608 217 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 83593629 Common - Alpha amylase, catalytic region Rru_A2294 150 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83591347 Nonpathogen - hypothetical protein Rru_A0007 1 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 83592651 Nonpathogen - Sterol-binding Rru_A1315 13 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 83594647 Common - Gamma-glutamyltransferase Rru_A3318 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 83592686 Common - Sodium/hydrogen exchanger Rru_A1350 42 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 83594748 Common - phosphoenolpyruvate carboxykinase Rru_A3419 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 83592563 Common - H+-transporting two-sector ATPase, delta/epsilon subunit Rru_A1227 171 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 83594290 Common - Major facilitator superfamily MFS_1 Rru_A2959 164 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83594001 Common - Ribosomal protein L15 Rru_A2669 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 83594556 Common - enoyl-(acyl carrier protein) reductase Rru_A3226 232 COG0623 FabI, Enoyl- acyl-carrier-protein 83592608 Common - Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain Rru_A1272 190 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83591683 Nonpathogen - hypothetical protein Rru_A0343 2 None None None 83592443 Common - hypothetical protein Rru_A1107 7 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83592027 Common - glutamyl-tRNA synthetase Rru_A0688 244 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 83592640 Common - urocanate hydratase Rru_A1304 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 83592824 Common - Metallophosphoesterase Rru_A1488 71 None None None 83592920 Common - putative depolymerase Rru_A1585 10 None None None 83593038 Common - Thymidylate kinase Rru_A1703 202 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 83595052 Common - bifunctional glutathionylspermidine amidase/glutathionylspermidine synthetase Rru_A3723 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 83593345 Common - Aminotransferase, class V Rru_A2010 152 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 83593336 Common - hypothetical protein Rru_A2001 36 COG3528 COG3528, Uncharacterized protein conserved in bacteria Function unknown 83593906 Common - Transcriptional Regulator, BadM/Rrf2 family Rru_A2574 150 COG1959 COG1959, Predicted transcriptional regulator Transcription 83594640 Common - ISMca6, transposase, OrfB Rru_A3310 17 None None None 83591520 Nonpathogen - hypothetical protein Rru_A0180 1 None None None 83594591 Nonpathogen - hypothetical protein Rru_A3261 1 None None None 83591352 Common - hypothetical protein Rru_A0012 12 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 83594412 Common - Predicted transcriptional regulator Rru_A3082 36 COG3636 COG3636, Predicted transcriptional regulator Transcription 83594645 Common - Phage integrase Rru_A3316 48 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 83593928 Common - Protein of unknown function DUF1212 Rru_A2596 30 COG2966 COG2966, Uncharacterized conserved protein Function unknown 83594238 Common - Transcriptional Regulator, AsnC family Rru_A2906 169 COG1522 Lrp, Transcriptional regulators Transcription 83592354 Common - extracellular solute-binding protein, family 1 Rru_A1018 127 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 83591805 Common - Phosphoserine phosphatase SerB Rru_A0465 145 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 83593057 Common - Protein of unknown function DUF1345 Rru_A1722 40 COG4291 COG4291, Predicted membrane protein Function unknown 83592385 Nonpathogen - GGDEF family protein Rru_A1049 5 None None None 83594694 Common - GTP-binding protein LepA Rru_A3365 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 83591616 Common - Polyhydroxyalkanoate synthesis repressor PhaR Rru_A0276 64 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 83592325 Common - Twin-arginine translocation pathway signal Rru_A0989 74 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 83591801 Common - Transcriptional Regulator, LysR family Rru_A0461 132 COG0583 LysR, Transcriptional regulator Transcription 83595043 Nonpathogen - hypothetical protein Rru_A3714 3 None None None 83592658 Common - alpha subunit of malonate decarboxylase Rru_A1322 27 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 83591733 Common - NUDIX hydrolase Rru_A0393 142 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83594305 Nonpathogen - Photosynthetic reaction centre protein L subunit Rru_A2975 17 None None None 83593880 Common - hypothetical protein Rru_A2545 51 COG1238 COG1238, Predicted membrane protein Function unknown 83593596 Nonpathogen - hypothetical protein Rru_A2261 1 None None None 83591377 Nonpathogen - Heme exporter protein D (CcmD) Rru_A0037 1 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 83592183 Common - PepSY-associated TM helix Rru_A0847 5 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 83592907 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Rru_A1572 90 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 83593664 Common - Cobyrinic acid a,c-diamide synthase Rru_A2329 209 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83593554 Common - Dihydroneopterin aldolase family Rru_A2219 68 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 83592820 Common - Glycosyl transferase WecB/TagA/CpsF Rru_A1484 122 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 83591656 Common - NADH-ubiquinone oxidoreductase Rru_A0316 195 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 83592882 Common - hypothetical protein Rru_A1547 169 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 83592468 Common - Anthranilate synthase Rru_A1132 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 83594360 Common - UDP-N-acetylglucosamine pyrophosphorylase Rru_A3030 227 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 83594887 Common - hypothetical protein Rru_A3558 133 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 83593571 Common - UspA Rru_A2236 27 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 83594880 Common - Aldo/keto reductase Rru_A3551 191 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 83592477 Common - hypothetical protein Rru_A1141 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 83592557 Nonpathogen - hypothetical protein Rru_A1221 15 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 83593600 Common - Electron transfer flavoprotein-ubiquinone oxidoreductase Rru_A2265 164 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 83593939 Nonpathogen - hypothetical protein Rru_A2607 1 None None None 83594822 Common - Hpt domain protein Rru_A3493 9 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 83591647 Common - Hydrogenase expression/formation protein (HUPF/HYPC) Rru_A0307 87 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 83591574 Nonpathogen - hypothetical protein Rru_A0234 3 None None None 83592816 Common - hypothetical protein Rru_A1480 12 None None None 83593609 Common nikD nickel transporter ATP-binding protein Rru_A2274 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83592319 Common - amidase Rru_A0983 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 83592365 Common - Transcriptional Regulator, AraC family Rru_A1029 71 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83593559 Common - Transcriptional Regulator, MarR family Rru_A2224 42 COG1846 MarR, Transcriptional regulators Transcription 83595018 Nonpathogen - MaoC-like dehydratase Rru_A3689 2 COG2030 MaoC, Acyl dehydratase Lipid metabolism 83594147 Common - Molybdopterin biosynthesis MoaE Rru_A2815 142 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 83593196 Nonpathogen - hypothetical protein Rru_A1861 1 None None None 83594895 Common - HemY-like Rru_A3566 30 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 83592292 Common - Peptidoglycan glycosyltransferase Rru_A0956 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 83594355 Common - hypothetical protein Rru_A3025 10 None None None 83591353 Common - hypothetical protein Rru_A0013 19 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 83591740 Common - hypothetical protein Rru_A0400 13 None None None 83594829 Common - cobalt transport protein CbiM Rru_A3500 30 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 83594266 Common - Putative diguanylate phosphodiesterase (EAL domain) Rru_A2934 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83593858 Common - Predicted transcriptional regulator Rru_A2523 142 COG1733 COG1733, Predicted transcriptional regulators Transcription 83594071 Nonpathogen - hypothetical protein Rru_A2739 2 None None None 83592437 Common - hypothetical protein Rru_A1101 12 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83593587 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Rru_A2252 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 83594479 Common - Protein of unknown function DUF214 Rru_A3149 8 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 83594718 Common - Protein of unknown function DUF403 Rru_A3389 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 83592871 Common - UvrD/REP helicase Rru_A1536 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 83594160 Nonpathogen - hypothetical protein Rru_A2828 2 None None None 83591678 Common - hypothetical protein Rru_A0338 24 None None None 83591480 Common - Transcriptional Regulator, AraC family Rru_A0140 69 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83594389 Common - Protein of unknown function DUF179 Rru_A3059 129 COG1678 COG1678, Putative transcriptional regulator Transcription 83591380 Common - Heme exporter protein CcmA Rru_A0040 187 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 83591554 Common - MutT/nudix family protein Rru_A0214 18 None None None 83593791 Common - D-3-phosphoglycerate dehydrogenase Rru_A2456 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 83591950 Nonpathogen - hypothetical protein Rru_A0611 1 None None None 83592375 Nonpathogen - hypothetical protein Rru_A1039 1 None None None 83593354 Common - Plasmid maintenance system antidote protein Rru_A2019 74 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 83594443 Common - hypothetical protein Rru_A3113 24 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 83592848 Common - ISSo9, nucleotidyltransferase domain protein Rru_A1512 26 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 83593382 Common - extracellular solute-binding protein, family 1 Rru_A2047 92 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 83592748 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A1412 95 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 83593228 Common - Protein of unknown function DUF610, YibQ Rru_A1893 68 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 83594734 Common - Formaldehyde dehydrogenase (glutathione) Rru_A3405 194 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 83593447 Nonpathogen - hypothetical protein Rru_A2112 2 None None None 83593521 Common - putative transposase Rru_A2186 20 None None None 83591555 Common - Protein of unknown function DUF6, transmembrane Rru_A0215 108 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83591784 Common - Sua5/YciO/YrdC/YwlC Rru_A0444 180 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 83594708 Common - TPR repeat Rru_A3379 11 COG2912 COG2912, Uncharacterized conserved protein Function unknown 83592420 Common - 5-formyltetrahydrofolate cyclo-ligase Rru_A1084 175 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 83594019 Common - Ribosomal protein L4/L1e Rru_A2687 220 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 83593097 Common - Protein of unknown function DUF598 Rru_A1762 55 COG3737 COG3737, Uncharacterized conserved protein Function unknown 83594843 Common - DNA polymerase A Rru_A3514 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 83593068 Nonpathogen - hypothetical protein Rru_A1733 5 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 83592047 Common - Phosphoribosylformylglycinamidine synthase II Rru_A0708 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 83594989 Common - tRNA and rRNA cytosine-C5-methylase Rru_A3660 205 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 83595089 Common - regulatory protein GntR Rru_A3760 140 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83593755 Common - transferase hexapeptide repeat Rru_A2420 190 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 83593736 Common - RuBisCO transcriptional regulator cbbR, LysR family Rru_A2401 192 COG0583 LysR, Transcriptional regulator Transcription 83592343 Common - Nitrogenase-associated protein Rru_A1007 18 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 83594625 Common - circadian clock protein KaiC Rru_A3295 67 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 83592301 Common - (2Fe-2S)-binding protein Rru_A0965 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 83591721 Common - Major facilitator superfamily transporter MFS_1 Rru_A0381 183 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83594800 Common - RecR protein Rru_A3471 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 83593090 Nonpathogen - hypothetical protein Rru_A1755 1 None None None 83593548 Common - sulfotransferase Rru_A2213 49 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 83593351 Nonpathogen - hypothetical protein Rru_A2016 10 None None None 83592766 Nonpathogen - hypothetical protein Rru_A1430 2 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 83592597 Common - Binding-protein-dependent transport systems inner membrane component Rru_A1261 173 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 83593682 Nonpathogen - hypothetical protein Rru_A2347 5 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 83594470 Common - Gluconate transporter Rru_A3140 76 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 83591858 Common - hypothetical protein Rru_A0519 10 None None None 83594136 Common - ABC transporter component Rru_A2804 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83592201 Common - TonB-dependent receptor Rru_A0865 123 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 83592413 Common - Elongation factor P Rru_A1077 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 83591628 Common - 2,5-didehydrogluconate reductase Rru_A0288 178 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 83594968 Common - coproporphyrinogen III oxidase Rru_A3639 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 83593648 Nonpathogen - hypothetical protein Rru_A2313 1 None None None 83595099 Common - tRNA-i(6)A37 modification enzyme MiaB Rru_A3770 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 83592933 Common - Protein of unknown function DUF1009 Rru_A1598 44 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 83591410 Common - Protein of unknown function DUF6, transmembrane Rru_A0070 95 COG2962 RarD, Predicted permeases General function prediction only 83594089 Common - chemotaxis sensory transducer Rru_A2757 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592789 Common - Phage Tail Collar Rru_A1453 35 COG4675 MdpB, Microcystin-dependent protein Function unknown 83592173 Common - Leucine-rich repeat Rru_A0837 40 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 83592119 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0780 168 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83594116 Common - Basic membrane lipoprotein Rru_A2784 103 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 83593306 Common - PfkB Rru_A1971 118 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 83594477 Nonpathogen - hypothetical protein Rru_A3147 1 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 83593362 Common - Aminotransferase, class V Rru_A2027 228 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 83593525 Common - TRm3 transposase Rru_A2190 11 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 83593723 Common - ABC-3 transporter component Rru_A2388 75 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 83591736 Common - Diaminopimelate decarboxylase Rru_A0396 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 83592150 Common - Helix-turn-helix protein, CopG Rru_A0811 23 None None None 83595084 Common - Heat shock protein Hsp20 Rru_A3755 65 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 83592953 Nonpathogen - hypothetical protein Rru_A1618 1 None None None 83592187 Common - HPr kinase Rru_A0851 2 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 83592700 Common - ABC transporter component Rru_A1364 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 83594547 Nonpathogen - hypothetical protein Rru_A3217 1 None None None 83591511 Common - CRISPR-associated CT1976 family protein Rru_A0171 33 None None None 83594425 Nonpathogen - hypothetical protein Rru_A3095 2 None None None 83591506 Common - hypothetical protein Rru_A0166 10 None None None 83594246 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Rru_A2914 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83594725 Common - Autoinducer synthesis protein Rru_A3396 19 COG3916 LasI, N-acyl-L-homoserine lactone synthetase Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 83592757 Common - Respiratory-chain NADH dehydrogenase, subunit 1 Rru_A1421 192 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 83591472 Common - Peptidase S13, D-Ala-D-Ala carboxypeptidase C Rru_A0132 103 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 83593275 Common - Pyruvate carboxyltransferase Rru_A1940 199 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 83594698 Nonpathogen - hypothetical protein Rru_A3369 1 None None None 83593533 Common - hypothetical protein Rru_A2198 86 COG1720 COG1720, Uncharacterized conserved protein Function unknown 83592361 Common - Rare lipoprotein A Rru_A1025 135 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 83592573 Common - Cytidylyltransferase Rru_A1237 56 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 83592552 Nonpathogen - hypothetical protein Rru_A1216 1 None None None 83591508 Common - hypothetical protein Rru_A0168 24 None None None 83594857 Nonpathogen - hypothetical protein Rru_A3528 1 None None None 83591376 Common - cytochrome c-type biogenesis protein CcmE Rru_A0036 95 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 83593338 Common - Radical SAM Rru_A2003 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 83594530 Common - Binding-protein-dependent transport systems inner membrane component Rru_A3200 41 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 83593343 Common - thiamine biosynthesis protein ThiC Rru_A2008 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 83593267 Nonpathogen - hypothetical protein Rru_A1932 8 None None None 83594521 Common - Dihydroorotase multifunctional complex type Rru_A3191 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 83593212 Common - lipoyl synthase Rru_A1877 191 COG0320 LipA, Lipoate synthase Coenzyme metabolism 83593221 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Rru_A1886 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 83594899 Common - Protein of unknown function DUF29 Rru_A3570 15 None None None 83591621 Common - Queuosine biosynthesis protein Rru_A0281 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 83595050 Common - sugar transferase Rru_A3721 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 83592271 Common - NAD-dependent epimerase/dehydratase Rru_A0935 230 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83593408 Common - Ribonuclease D Rru_A2073 122 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 83592408 Common rpmE 50S ribosomal protein L31 Rru_A1072 166 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 83594601 Common - glutathione S-transferase family protein Rru_A3271 67 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83592745 Common - L-lactate permease Rru_A1409 103 COG1620 LldP, L-lactate permease Energy production and conversion 83594930 Common - Transcriptional Regulator, XRE family Rru_A3601 12 COG1396 HipB, Predicted transcriptional regulators Transcription 83594963 Common - hypothetical protein Rru_A3634 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 83592481 Common - Pyridoxal kinase Rru_A1145 124 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 83594737 Common - Glycosyl transferase, family 2 Rru_A3408 191 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83592704 Nonpathogen - hypothetical protein Rru_A1368 1 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 83592829 Common - UDP-N-acetylglucosamine 2-epimerase Rru_A1493 152 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 83591752 Nonpathogen - hypothetical protein Rru_A0412 1 None None None 83591456 Nonpathogen - hypothetical protein Rru_A0116 1 None None None 83593117 Common - Copper/Zinc superoxide dismutase Rru_A1782 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 83593799 Common - Hydroxypyruvate reductase Rru_A2464 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 83592082 Common - Aspartate kinase Rru_A0743 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 83594045 Nonpathogen - hypothetical protein Rru_A2713 1 None None None 83592278 Common - nucleoside diphosphate kinase regulator Rru_A0942 82 COG0782 GreA, Transcription elongation factor Transcription 83592763 Common - Carbon-monoxide dehydrogenase, catalytic subunit Rru_A1427 25 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 83594362 Common - hypothetical protein Rru_A3032 14 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 83591743 Common - Short-chain dehydrogenase/reductase SDR Rru_A0403 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83592649 Common - Membrane protein involved in aromatic hydrocarbon degradation Rru_A1313 77 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 83593984 Nonpathogen - hypothetical protein Rru_A2652 3 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 83595112 Common truB tRNA pseudouridine synthase B Rru_A3783 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 83592718 Common - Butyrate-acetoacetate CoA-transferase Rru_A1382 94 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 83592929 Common - surface antigen D15 Rru_A1594 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 83591735 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Rru_A0395 158 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 83594183 Nonpathogen - hypothetical protein Rru_A2851 2 COG5373 COG5373, Predicted membrane protein Function unknown 83592499 Common - Nickel-dependent hydrogenase b-type cytochrome subunit Rru_A1163 42 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 83591998 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with Response Regulator Receiver modulation Rru_A0659 166 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83591824 Common - hypothetical protein Rru_A0484 54 COG0392 COG0392, Predicted integral membrane protein Function unknown 83594464 Common - AMP-dependent synthetase and ligase Rru_A3134 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83592736 Common - CheW protein Rru_A1400 125 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83593693 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2358 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83592999 Common - conserved hypothetical cytosolic protein Rru_A1664 29 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 83592091 Common - hypothetical protein Rru_A0752 32 COG5373 COG5373, Predicted membrane protein Function unknown 83594656 Common - hypothetical protein Rru_A3327 2 None None None 83592368 Common - Ethanolamine ammonia lyase large subunit Rru_A1032 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 83591921 Common - Tetraacyldisaccharide 4'-kinase Rru_A0582 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 83593106 Common - Sec-independent periplasmic protein translocase Rru_A1771 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 83594397 Common - Transcriptional Regulator, TetR family Rru_A3067 40 COG1309 AcrR, Transcriptional regulator Transcription 83593806 Common - hypothetical protein Rru_A2471 9 None None None 83594687 Common - Methylated-DNA--(protein)-cysteine S-methyltransferase Rru_A3358 197 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 83594100 Common - Maf-like protein Rru_A2768 195 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 83592599 Common - Binding-protein-dependent transport systems inner membrane component Rru_A1263 150 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 83591965 Nonpathogen - Transcriptional Regulator, Fis family Rru_A0626 9 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83593114 Common - Arginine--tRNA ligase Rru_A1779 242 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83594974 Common - NAD-dependent deacetylase Rru_A3645 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 83593700 Common - ATP-dependent helicase HrpB Rru_A2365 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 83592491 Common - potassium-transporting ATPase subunit A Rru_A1155 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 83593188 Common - Peptidase S26A, signal peptidase I Rru_A1853 212 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 83594010 Common - Ribosomal protein L14 Rru_A2678 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 83593616 Common - NifQ Rru_A2281 22 None None None 83594442 Common - 4-cresol dehydrogenase (hydroxylating) Rru_A3112 93 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83592521 Common rpsP 30S ribosomal protein S16 Rru_A1185 209 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 83591842 Common lysK lysyl-tRNA synthetase Rru_A0503 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 83593120 Common - membrane protein-like Rru_A1785 13 COG3671 COG3671, Predicted membrane protein Function unknown 83594049 Common - Isochorismatase hydrolase Rru_A2717 74 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 83593008 Common - CutA1 divalent ion tolerance protein Rru_A1673 111 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 83594369 Common - PAS/PAC Sensor Hybrid Histidine Kinase Rru_A3039 207 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83594336 Common - Protein of unknown function DUF839 Rru_A3006 66 COG3211 PhoX, Predicted phosphatase General function prediction only 83592519 Common - Diaminopimelate epimerase Rru_A1183 198 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 83593819 Common - chemotaxis sensory transducer Rru_A2484 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83591780 Common - Xylose isomerase-like TIM barrel Rru_A0440 9 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 83593032 Nonpathogen - hypothetical protein Rru_A1697 1 COG4260 COG4260, Putative virion core protein (lumpy skin disease virus) Function unknown 83592332 Common - Leucine rich repeat variant Rru_A0996 14 None None None 83594484 Common - hypothetical protein Rru_A3154 14 COG4457 SrfB, Uncharacterized protein conserved in bacteria, putative virulence factor Function unknown 83595076 Common - peptidyl-tRNA hydrolase Rru_A3747 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 83591813 Common - Peptidoglycan glycosyltransferase Rru_A0473 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 83591429 Common - ATP-dependent DNA helicase RecQ Rru_A0089 222 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 83593184 Common recO DNA repair protein RecO Rru_A1849 35 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 83593237 Common - Basic membrane lipoprotein Rru_A1902 99 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 83592149 Nonpathogen - hypothetical protein Rru_A0810 6 None None None 83593128 Common - hypothetical protein Rru_A1793 152 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83592215 Common - Transcriptional Regulator, AraC family Rru_A0879 125 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83593052 Common - Transcriptional Regulator, ArsR family Rru_A1717 148 COG0640 ArsR, Predicted transcriptional regulators Transcription 83593829 Common - Glycosyl transferase, family 2 Rru_A2494 98 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83593431 Common - Cell divisionFtsK/SpoIIIE Rru_A2096 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 83594493 Common - 3-deoxy-manno-octulosonate cytidylyltransferase Rru_A3163 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 83591491 Common - hypothetical protein Rru_A0151 39 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 83592132 Common - Nitrogenase Rru_A0793 63 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83592239 Common - Pyruvate formate-lyase Rru_A0903 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 83592772 Common - Histidine Kinase Rru_A1436 190 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83593610 Common nikC nickel transporter permease NikC Rru_A2275 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83593206 Common - Na/Pi cotransporter II-related Rru_A1871 82 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 83593650 Common - PepSY-associated TM helix Rru_A2315 35 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 83592268 Common - Sigma54 Specific Transcriptional Regulator containing GAF, and Fis DNA-binding domains Rru_A0932 176 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 83591407 Nonpathogen - Protein of unknown function DUF123 Rru_A0067 11 COG1833 COG1833, Uncharacterized conserved protein Function unknown 83595127 Common - Ubiquinone/menaquinone biosynthesis methyltransferase Rru_A3798 200 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83591948 Common - UspA Rru_A0609 69 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 83592501 Nonpathogen - Hydrogenase expression/formation protein (HUPF/HYPC) Rru_A1165 1 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 83594132 Common - hypothetical protein Rru_A2800 23 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 83591774 Common - Organic solvent tolerance protein OstA-like Rru_A0434 105 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 83592190 Common - Sulfotransferase Rru_A0854 20 None None None 83593425 Common - ABC transporter component Rru_A2090 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 83593094 Common - putative phytoene synthase protein Rru_A1759 55 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 83593299 Common - adenylosuccinate synthetase Rru_A1964 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 83592410 Common - MotA/TolQ/ExbB proton channel family protein Rru_A1074 28 None None None 83592120 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Rru_A0781 171 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83593289 Common - Secretion protein HlyD Rru_A1954 94 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83594508 Common - Holliday junction resolvase YqgF Rru_A3178 136 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 83592164 Common - CRISPR-associated helicase Cas3, core Rru_A0828 70 COG1203 COG1203, Predicted helicases General function prediction only 83591546 Common - Cobalt chelatase, pCobS small subunit Rru_A0206 55 COG0714 COG0714, MoxR-like ATPases General function prediction only 83594347 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Rru_A3017 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83594809 Common - succinyl-diaminopimelate desuccinylase Rru_A3480 199 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 83594078 Common - DegT/DnrJ/EryC1/StrS aminotransferase Rru_A2746 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 83593581 Common - Glucose-1-phosphate adenylyltransferase Rru_A2246 186 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 83593084 Common - ABC transporter component Rru_A1749 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83594868 Common - PII uridylyl-transferase Rru_A3539 125 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 83591718 Nonpathogen - hypothetical protein Rru_A0378 1 None None None 83591363 Nonpathogen - hypothetical protein Rru_A0023 1 None None None 83594068 Common - hypothetical protein Rru_A2736 25 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 83595106 Common trmB tRNA (guanine-N(7))-methyltransferase Rru_A3777 172 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 83592965 Nonpathogen - hypothetical protein Rru_A1630 2 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 83593710 Nonpathogen - hypothetical protein Rru_A2375 1 None None None 83593941 Common - hypothetical protein Rru_A2609 17 None None None 83594447 Common - Polysaccharide export protein Rru_A3117 94 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 83592922 Common tsf elongation factor Ts Rru_A1587 215 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 83591960 Common bchH magnesium chelatase subunit H Rru_A0621 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 83592178 Nonpathogen - hypothetical protein Rru_A0842 1 None None None 83593757 Nonpathogen - hypothetical protein Rru_A2422 1 None None None 83594476 Nonpathogen - hypothetical protein Rru_A3146 1 None None None 83592899 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 Rru_A1564 109 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 83591762 Nonpathogen - hypothetical protein Rru_A0422 1 None None None 83591888 Nonpathogen - hypothetical protein Rru_A0549 1 None None None 83593474 Nonpathogen - hypothetical protein Rru_A2139 1 None None None 83594954 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Rru_A3625 193 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 83594663 Common - Putative ammonia monooxygenase Rru_A3334 50 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 83594014 Common rpsC 30S ribosomal protein S3 Rru_A2682 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 83592062 Common - Amine oxidase Rru_A0723 67 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 83593262 Common - Acetyl-CoA hydrolase Rru_A1927 95 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 83593280 Common - Short-chain dehydrogenase/reductase SDR Rru_A1945 144 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 83595088 Common - hypothetical protein Rru_A3759 75 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83591563 Common - Protein of unknown function DUF344 Rru_A0223 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 83592693 Common - transaldolase B Rru_A1357 180 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 83593491 Common - enoyl-CoA hydratase Rru_A2156 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83594838 Common - AMP-dependent synthetase and ligase Rru_A3509 200 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 83594382 Nonpathogen - hypothetical protein Rru_A3052 6 None None None 83592868 Common - Pentapeptide repeat Rru_A1533 92 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 83594200 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A2868 172 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83594125 Common - Protein of unknown function DUF1006 Rru_A2793 61 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 83591393 Common - Carboxyl transferase Rru_A0053 215 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 83593019 Common hfq RNA-binding protein Hfq Rru_A1684 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 83594630 Common - ABC transporter component Rru_A3300 198 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 83592724 Common - Transcriptional Regulator, NifA subfamily, Fis Family Rru_A1388 173 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 83594675 Common - Polysaccharide biosynthesis protein Rru_A3346 72 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 83593515 Common - Peptidase S33, tricorn interacting factor 1 Rru_A2180 34 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83594639 Common - Sulfotransferase Rru_A3309 26 None None None 83593480 Nonpathogen - hypothetical protein Rru_A2145 1 None None None 83593810 Common - Glycine betaine/L-proline transport ATP-binding subunit Rru_A2475 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 83592779 Nonpathogen - hypothetical protein Rru_A1443 6 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 83593785 Common - Peptidase M48, Ste24p Rru_A2450 122 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83594063 Nonpathogen - Exopolysaccharide synthesis, ExoD Rru_A2731 2 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 83592359 Nonpathogen - hypothetical protein Rru_A1023 1 None None None 83594679 Common - Peptide deformylase Rru_A3350 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 83593874 Nonpathogen - hypothetical protein Rru_A2539 1 None None None 83594568 Common - hypothetical protein Rru_A3238 10 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 83591726 Common - Transcriptional Regulator, ArsR family Rru_A0386 35 COG0640 ArsR, Predicted transcriptional regulators Transcription 83593403 Common mgsA methylglyoxal synthase Rru_A2068 87 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 83591693 Common - Phage Transcriptional Regulator, AlpA Rru_A0353 19 COG3311 AlpA, Predicted transcriptional regulator Transcription 83592104 Nonpathogen - hypothetical protein Rru_A0765 4 None None None 83594251 Common - hypothetical protein Rru_A2919 18 None None None 83594859 Common - DNA polymerase IV Rru_A3530 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 83591905 Common - hypothetical protein Rru_A0566 52 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 83591444 Common - Alpha-2-macroglobulin-like protein Rru_A0104 78 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 83593556 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Rru_A2221 201 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 83593241 Common - Sulfate transporter/antisigma-factor antagonist Rru_A1906 160 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 83594458 Common - Transcriptional Regulator, AraC family Rru_A3128 91 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83592508 Common - Transcriptional Regulator, AsnC family Rru_A1172 152 COG1522 Lrp, Transcriptional regulators Transcription 83592676 Common - Glycerone kinase Rru_A1340 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 83593994 Common - Peptidase S1C, Do Rru_A2662 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 83591785 Common - 3(2),5 -bisphosphate nucleotidase Rru_A0445 138 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 83591430 Common - Prevent-host-death protein Rru_A0090 11 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 83593414 Common - Glutamate--ammonia ligase Rru_A2079 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 83595049 Common - Polysaccharide biosynthesis protein Rru_A3720 6 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 83594325 Nonpathogen - hypothetical protein Rru_A2995 3 None None None 83593957 Common - Ribonuclease BN Rru_A2625 87 COG1295 Rbn, Predicted membrane protein Function unknown 83593704 Common - hypothetical protein Rru_A2369 114 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 83595008 Common - Rod shape-determining protein RodA Rru_A3679 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 83593290 Common - Phosphoribosyltransferase Rru_A1955 10 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 83593602 Common - Electron transfer flavoprotein beta-subunit Rru_A2267 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 83594300 Common - precorrin 6A synthase Rru_A2970 68 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 83593394 Common - Metal dependent phosphohydrolase, HD region Rru_A2059 52 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 83594945 Common - Uroporphyrinogen decarboxylase HemE Rru_A3616 178 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 83591887 Nonpathogen - Flagellar hook-length control protein Rru_A0548 9 COG5373 COG5373, Predicted membrane protein Function unknown 83595034 Common - Cell divisionFtsK/SpoIIIE Rru_A3705 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 83594529 Common - extracellular solute-binding protein, family 1 Rru_A3199 112 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 83592535 Common - Pyridoxal kinase Rru_A1199 71 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 83592352 Common - Binding-protein-dependent transport systems inner membrane component Rru_A1016 215 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 83592453 Common - Secretion protein HlyD Rru_A1117 142 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83592199 Common - ABC transporter, transmembrane region Rru_A0863 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83591881 Common - flagellar motor switch protein Rru_A0542 125 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 83593889 Common - chemotaxis sensory transducer Rru_A2554 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593073 Common - hypothetical protein Rru_A1738 24 COG1598 COG1598, Uncharacterized conserved protein Function unknown 83593868 Common - Flagellar hook capping protein Rru_A2533 95 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 83591522 Common - hypothetical protein Rru_A0182 5 None None None 83591392 Common - Biotin carboxylase Rru_A0052 240 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 83591423 Nonpathogen - nuclease, SNase-like Rru_A0083 2 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 83592230 Common - stress protein Rru_A0894 31 COG2310 TerZ, Uncharacterized proteins involved in stress response, homologs of TerZ and putative cAMP-binding protein CABP1 Signal transduction mechanisms 83594143 Common - hypothetical protein Rru_A2811 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 83592688 Nonpathogen - hypothetical protein Rru_A1352 1 None None None 83591667 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Rru_A0327 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83594418 Common - hypothetical protein Rru_A3088 28 None None None 83594558 Common - cyclase/dehydrase Rru_A3228 73 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 83592009 Common - Cobalbumin biosynthesis enzyme Rru_A0670 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 83593347 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2012 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83593388 Common - Phenylacrylic acid decarboxylase Rru_A2053 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 83591666 Common - Transcriptional Regulator, NifA subfamily, Fis Family Rru_A0326 171 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 83594340 Common - Transcriptional Regulator, DeoR family Rru_A3010 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 83592560 Common - ATP synthase F1, alpha subunit Rru_A1224 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 83593476 Common - Protein of unknown function DUF6, transmembrane Rru_A2141 84 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83591991 Common - Pseudouridine synthase, Rsu Rru_A0652 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 83592826 Common - Protein-tyrosine kinase Rru_A1490 153 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 83594378 Common - glycine dehydrogenase subunit 2 Rru_A3048 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 83593219 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Rru_A1884 206 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83594841 Common - glutamine amidotransferase Rru_A3512 145 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 83594263 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Rru_A2931 208 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 83594772 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Rru_A3443 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83591447 Common - MSHA biogenesis protein MshM Rru_A0107 40 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 83594090 Common - Response regulator receiver domain protein (CheY) Rru_A2758 187 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83593083 Common - ABC transporter component Rru_A1748 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83593517 Common - NAD(P)(+) transhydrogenase (AB-specific) Rru_A2182 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 83593919 Common - hypothetical protein Rru_A2587 6 None None None 83593137 Common - chemotaxis sensory transducer Rru_A1802 165 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594980 Common - ABC transporter component Rru_A3651 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 83594909 Common - Protein of unknown function DUF6, transmembrane Rru_A3580 101 COG2962 RarD, Predicted permeases General function prediction only 83592565 Common - hypothetical protein Rru_A1229 36 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 83591808 Common ilvH acetolactate synthase 3 regulatory subunit Rru_A0468 188 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 83592627 Common - ABC transporter component Rru_A1291 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83591708 Common - Protein of unknown function DUF1285 Rru_A0368 45 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 83592941 Common - Glycogen debranching enzyme GlgX Rru_A1606 164 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 83594752 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Rru_A3423 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83591776 Common - hypothetical protein Rru_A0436 5 None None None 83594292 Common - Zinc-containing alcohol dehydrogenase superfamily Rru_A2962 103 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83593070 Common - hypothetical protein Rru_A1735 13 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83591819 Common - Radical SAM Rru_A0479 39 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 83593544 Common - AsmA Rru_A2209 64 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 83594658 Common - hypothetical protein Rru_A3329 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 83593564 Common - Response regulator receiver domain protein (CheY) Rru_A2229 130 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83592074 Common - Sugar fermentation stimulation protein Rru_A0735 99 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 83593029 Common - hypothetical protein Rru_A1694 12 None None None 83594221 Common - hypothetical protein Rru_A2889 4 None None None 83595094 Common - hypothetical protein Rru_A3765 22 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 83591865 Common fliI flagellum-specific ATP synthase Rru_A0526 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 83591798 Common - hypothetical protein Rru_A0458 16 None None None 83591974 Common actP acetate permease Rru_A0635 179 COG4147 DhlC, Predicted symporter General function prediction only 83592583 Common - Transcriptional Regulator, XRE family Rru_A1247 13 COG1476 COG1476, Predicted transcriptional regulators Transcription 83591454 Common - type II secretion system protein Rru_A0114 138 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 83593243 Common - Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor and Response Regulator Receiver modulation Rru_A1908 182 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83594456 Nonpathogen - hypothetical protein Rru_A3126 9 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 83591387 Common - ABC transporter component Rru_A0047 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 83593646 Common - Transcriptional Regulator, IclR family Rru_A2311 51 COG1414 IclR, Transcriptional regulator Transcription 83594586 Common - Protein of unknown function DUF218 Rru_A3256 31 COG1434 COG1434, Uncharacterized conserved protein Function unknown 83594928 Common - ATP-dependent protease peptidase subunit Rru_A3599 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 83593675 Common - ABC transporter, transmembrane region Rru_A2340 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83594836 Common - inner-membrane translocator Rru_A3507 142 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 83592917 Common dnaE DNA polymerase III subunit alpha Rru_A1582 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 83593694 Common - Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like Rru_A2359 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83592647 Common - Transcriptional Regulator, MerR family Rru_A1311 120 COG0789 SoxR, Predicted transcriptional regulators Transcription 83593487 Common rplM 50S ribosomal protein L13 Rru_A2152 219 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 83593254 Common - Binding-protein-dependent transport systems inner membrane component Rru_A1919 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83594594 Common - histidinol-phosphate aminotransferase Rru_A3264 231 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 83594571 Common - chemotaxis sensory transducer Rru_A3241 127 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592979 Common - ABC transporter component Rru_A1644 247 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 83591345 Common - killer suppression protein HigA, putative Rru_A0005 7 None None None 83592227 Common - Tellurite resistance TerB Rru_A0891 16 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 83592256 Common - Acetate kinase Rru_A0920 162 COG0282 ackA, Acetate kinase Energy production and conversion 83593130 Common - HAD-superfamily hydrolase, subfamily IIA Rru_A1795 65 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 83594512 Common - Auxin Efflux Carrier Rru_A3182 62 COG0679 COG0679, Predicted permeases General function prediction only 83594287 Common - Glycine--tRNA ligase Rru_A2955 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 83593887 Nonpathogen - hypothetical protein Rru_A2552 1 None None None 83592594 Nonpathogen - hypothetical protein Rru_A1258 4 None None None 83592985 Nonpathogen - hypothetical protein Rru_A1650 2 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 83592043 Common - Molybdenum ABC transporter, periplasmic binding protein Rru_A0704 157 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 83592665 Common - transporter Rru_A1329 11 None None None 83594288 Common - pyruvate phosphate dikinase Rru_A2956 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 83594218 Common carB carbamoyl phosphate synthase large subunit Rru_A2886 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 83593926 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A2594 179 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83594033 Common secE preprotein translocase subunit SecE Rru_A2701 43 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 83594947 Common - hypothetical protein Rru_A3618 97 COG1981 COG1981, Predicted membrane protein Function unknown 83594527 Common - HicB Rru_A3197 30 COG4226 HicB, Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters Function unknown 83591967 Common - PUCC protein Rru_A0628 22 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 83591535 Nonpathogen - hypothetical protein Rru_A0195 4 None None None 83594037 Nonpathogen - hypothetical protein Rru_A2705 1 None None None 83594511 Nonpathogen - hypothetical protein Rru_A3181 1 COG5373 COG5373, Predicted membrane protein Function unknown 83594253 Common - TPR repeat Rru_A2921 31 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 83591953 Nonpathogen - hypothetical protein Rru_A0614 11 None None None 83592678 Common - hypothetical protein Rru_A1342 11 None None None 83592487 Nonpathogen - hypothetical protein Rru_A1151 1 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 83593412 Nonpathogen - hypothetical protein Rru_A2077 1 None None None 83591938 Common - Phosphate ABC transporter, permease protein PstC Rru_A0599 230 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 83595068 Nonpathogen - hypothetical protein Rru_A3739 3 None None None 83592316 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0980 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83592601 Common - Transcriptional Regulator, DeoR family Rru_A1265 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 83591594 Common - NAD-dependent epimerase/dehydratase Rru_A0254 180 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83592152 Common - hypothetical protein Rru_A0815 13 None None None 83594171 Nonpathogen - hypothetical protein Rru_A2839 7 None None None 83593634 Common - inner-membrane translocator Rru_A2299 126 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 83593840 Common - Response regulator receiver domain protein (CheY) Rru_A2505 127 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 83594080 Common - ABC transporter component Rru_A2748 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83592305 Common - VWA containing CoxE-like Rru_A0969 40 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 83591695 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Rru_A0355 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 83595016 Common - Cobalt transport protein Rru_A3687 25 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 83594900 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Rru_A3571 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 83594349 Common - hypothetical protein Rru_A3019 15 None None None 83594956 Common - Cobyrinic acid a,c-diamide synthase Rru_A3627 217 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83592439 Common - Phenazine biosynthesis PhzC/PhzF protein Rru_A1103 107 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 83594992 Common - NAD-glutamate dehydrogenase Rru_A3663 76 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 83591979 Common - ABC-2 transporter component Rru_A0640 163 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 83594191 Common - hypothetical protein Rru_A2859 59 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 83594427 Common - hypothetical protein Rru_A3097 48 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83591822 Common - Protein of unknown function DUF1311 Rru_A0482 26 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 83594935 Common - Protein of unknown function DUF224, cysteine-rich region Rru_A3606 142 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 83593760 Common - Peptidase M48 Rru_A2425 118 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83592616 Common - HPr kinase Rru_A1280 28 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 83593748 Common - Poly(R)-hydroxyalkanoic acid synthase, class I Rru_A2413 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 83594244 Nonpathogen - Propeptide, PepSY amd peptidase M4 Rru_A2912 1 None None None 83595026 Common - Fumarylacetoacetate (FAA) hydrolase Rru_A3697 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 83594155 Common - Flagellar biosynthesis protein FliQ Rru_A2823 126 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 83593210 Common - Multi-sensor Signal Transduction Histidine Kinase Rru_A1875 220 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 83592037 Common - Lipolytic enzyme Rru_A0698 113 COG0657 Aes, Esterase/lipase Lipid metabolism 83594149 Nonpathogen - Phasin Rru_A2817 16 COG5490 COG5490, Uncharacterized conserved protein Function unknown 83595064 Common - hypothetical protein Rru_A3735 25 COG5642 COG5642, Uncharacterized conserved protein Function unknown 83594273 Common - putative DNA-binding protein Rru_A2941 35 COG2944 COG2944, Predicted transcriptional regulator Transcription 83591572 Common - hypothetical protein Rru_A0232 28 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 83593165 Nonpathogen - hypothetical protein Rru_A1830 1 None None None 83591557 Common - Citrate lyase Rru_A0217 117 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 83593190 Common - hypothetical protein Rru_A1855 29 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 83594197 Common - Peptidase M24 Rru_A2865 193 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 83591754 Common - Ribosomal protein S6 Rru_A0414 197 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 83594445 Common - ATPase Rru_A3115 66 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 83592261 Common - Glycosyl transferase, group 1 Rru_A0925 78 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83592286 Common murG N-acetylglucosaminyl transferase Rru_A0950 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 83594163 Common - Acyltransferase 3 Rru_A2831 47 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 83593451 Common - UDP-glucose 6-dehydrogenase Rru_A2116 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 83593099 Common - SecD export membrane protein Rru_A1764 205 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 83593449 Common - O-antigen polymerase Rru_A2114 5 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 83593505 Common - ABC transporter component Rru_A2170 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 83592377 Common - Transcriptional Regulator, LysR family Rru_A1041 153 COG0583 LysR, Transcriptional regulator Transcription 83593230 Common - Glutamine amidotransferase of anthranilate synthase Rru_A1895 238 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 83591561 Common pgk phosphoglycerate kinase Rru_A0221 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 83592636 Common - N-formylglutamate deformylase Rru_A1300 59 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 83593641 Nonpathogen - hypothetical protein Rru_A2306 1 None None None 83594255 Nonpathogen - hypothetical protein Rru_A2923 8 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83594706 Common - Alpha/beta hydrolase fold Rru_A3377 69 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83595002 Common - Glutaconyl-CoA decarboxylase Rru_A3673 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 83592430 Common tolB translocation protein TolB Rru_A1094 153 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 83593898 Nonpathogen - hypothetical protein Rru_A2566 1 None None None 83591420 Common - chemotaxis sensory transducer Rru_A0080 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592071 Common - DNA repair protein RadC Rru_A0732 177 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 83592405 Nonpathogen - Putative Fe-S cluster Rru_A1069 13 COG2000 COG2000, Predicted Fe-S protein General function prediction only 83592025 Common - Transcriptional Regulator, LysR family Rru_A0686 137 COG0583 LysR, Transcriptional regulator Transcription 83595011 Common - Cytochrome B561 Rru_A3682 94 COG3038 CybB, Cytochrome B561 Energy production and conversion 83592808 Common - Acetate CoA-transferase Rru_A1472 105 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 83593849 Common - Twin-arginine translocation pathway signal Rru_A2514 60 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 83594307 Nonpathogen - Antenna complex, alpha/beta subunit Rru_A2977 8 None None None 83593316 Common - Succinylglutamate desuccinylase/aspartoacylase Rru_A1981 23 COG3608 COG3608, Predicted deacylase General function prediction only 83591981 Common - Protein of unknown function DUF185 Rru_A0642 85 COG1565 COG1565, Uncharacterized conserved protein Function unknown 83594087 Common - hypothetical protein Rru_A2755 69 None None None 83593239 Common - inner-membrane translocator Rru_A1904 105 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 83594871 Common - malic enzyme Rru_A3542 213 COG0281 SfcA, Malic enzyme Energy production and conversion 83591434 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0094 164 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 83593684 Common - hypothetical protein Rru_A2349 6 None None None 83594406 Common - Cobalamin adenosyltransferase Rru_A3076 129 COG2096 COG2096, Uncharacterized conserved protein Function unknown 83591778 Common - Multi-sensor Signal Transduction Histidine Kinase Rru_A0438 195 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83593378 Nonpathogen - hypothetical protein Rru_A2043 6 None None None 83594486 Common - von Willebrand factor, type A Rru_A3156 21 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 83593713 Common - transcriptional regulator with PAS/PAC domain Rru_A2378 91 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 83593528 Common - Abc1 protein Rru_A2193 183 COG0661 AarF, Predicted unusual protein kinase General function prediction only 83593030 Common - Protein of unknown function DUF411 Rru_A1695 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 83594711 Common - Cobalamin biosynthesis protein CbiB Rru_A3382 148 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 83591851 Common - hypothetical protein Rru_A0512 6 None None None 83594696 Common - Cob(I)alamin adenosyltransferase Rru_A3367 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 83592822 Common - UDP-glucose 4-epimerase Rru_A1486 158 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83594357 Common - Sulfotransferase Rru_A3027 18 None None None 83593442 Common - 23S rRNA (uracil-5-)-methyltransferase RumA Rru_A2107 172 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 83591675 Common - YbaK/prolyl-tRNA synthetase associated region Rru_A0335 94 COG2606 EbsC, Uncharacterized conserved protein Function unknown 83593930 Common - hypothetical protein Rru_A2598 27 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 83594643 Nonpathogen - minor capsid protein 10 Rru_A3313 3 None None None 83591485 Common - Transcriptional Regulator, TetR family Rru_A0145 96 COG1309 AcrR, Transcriptional regulator Transcription 83592656 Common - Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Rru_A1320 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 83591577 Common - Protein of unknown function DUF190 Rru_A0237 50 COG1993 COG1993, Uncharacterized conserved protein Function unknown 83595045 Common - Polysaccharide export protein Rru_A3716 68 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 83592127 Common - ABC transporter component Rru_A0788 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 83592901 Common - NADH dehydrogenase subunit L Rru_A1566 208 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 83593061 Common - Transcription-repair coupling factor Rru_A1726 223 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 83593937 Common - Phosphoheptose isomerase Rru_A2605 126 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 83595115 Common - Glycerophosphodiester phosphodiesterase Rru_A3786 129 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 83593964 Common - Peptidoglycan-binding domain 1 Rru_A2632 36 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 83592526 Common leuD isopropylmalate isomerase small subunit Rru_A1190 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 83591618 Common - Transcriptional Regulator, XRE family Rru_A0278 46 COG1396 HipB, Predicted transcriptional regulators Transcription 83594431 Common - hypothetical protein Rru_A3101 12 None None None 83592290 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase Rru_A0954 209 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 83592887 Common - Peptidase S16, ATP-dependent protease La Rru_A1552 222 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 83593804 Common - FeoA Rru_A2469 71 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 83592537 Common - MaoC-like dehydratase Rru_A1201 59 COG2030 MaoC, Acyl dehydratase Lipid metabolism 83593461 Common - 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase Rru_A2126 181 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 83591875 Common - Transcriptional Regulator, AraC family Rru_A0536 147 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83591649 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A0309 149 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 83594539 Common - Ribonuclease H Rru_A3209 203 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 83591633 Common rpsA 30S ribosomal protein S1 Rru_A0293 215 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 83594073 Common - Polysaccharide biosynthesis protein CapD Rru_A2741 137 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83593662 Common - CheA Signal Transduction Histidine Kinases (STHK) Rru_A2327 148 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 83593912 Nonpathogen - hypothetical protein Rru_A2580 1 None None None 83594410 Nonpathogen - hypothetical protein Rru_A3080 10 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 83594791 Common - Cold-shock DNA-binding domain protein Rru_A3462 163 COG1278 CspC, Cold shock proteins Transcription 83593420 Common - Nitrogen regulatory protein P-II (GlnB, GlnK) Rru_A2085 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 83591379 Common - Cytochrome c-type biogenesis protein CcmB Rru_A0039 80 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 83594380 Common - Glycine cleavage H-protein Rru_A3050 183 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 83592327 Common - hypothetical protein Rru_A0991 133 COG2860 COG2860, Predicted membrane protein Function unknown 83591988 Nonpathogen - hypothetical protein Rru_A0649 1 None None None 83594913 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Rru_A3584 149 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 83593577 Common - Glutathione-dependent formaldehyde-activating, GFA Rru_A2242 66 COG3791 COG3791, Uncharacterized conserved protein Function unknown 83594840 Common - aconitate hydratase Rru_A3511 222 COG1048 AcnA, Aconitase A Energy production and conversion 83591941 Common - Phosphate uptake regulator, PhoU Rru_A0602 202 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 83593109 Common - Predicted transcriptional regulator Rru_A1774 143 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 83594789 Common - Cyclic nucleotide-binding domain (cNMP-BD) protein Rru_A3460 44 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83591688 Common - CRISPR-associated protein, Cas2 Rru_A0348 8 None None None 83592012 Common - hypothetical protein Rru_A0673 2 None None None 83593010 Common - Cytochrome c assembly protein Rru_A1675 24 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 83594790 Common - Carbohydrate kinase, FGGY Rru_A3461 177 COG0554 GlpK, Glycerol kinase Energy production and conversion 83594065 Common - Glycosyl transferase, family 2 Rru_A2733 32 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 83593022 Common - Inositol monophosphatase Rru_A1687 166 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 83592538 Common - Succinate dehydrogenase, cytochrome b subunit Rru_A1202 71 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 83591713 Common - flavodoxin/nitric oxide synthase Rru_A0373 84 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 83591611 Common folE GTP cyclohydrolase I Rru_A0271 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 83594040 Nonpathogen - hypothetical protein Rru_A2708 1 None None None 83593325 Nonpathogen - hypothetical protein Rru_A1990 2 None None None 83595125 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase Rru_A3796 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 83593405 Common - FAD dependent oxidoreductase Rru_A2070 82 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 83592696 Common - Dak phosphatase Rru_A1360 71 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 83593172 Common - delta-aminolevulinic acid dehydratase Rru_A1837 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 83592924 Common - Ribosome recycling factor Rru_A1589 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 83594632 Common - Glucan 1,4-alpha-glucosidase Rru_A3302 6 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 83591750 Common - DnaB helicase Rru_A0410 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 83594570 Common - Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Rru_A3240 18 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 83592937 Common - ComEC/Rec2-related protein Rru_A1602 107 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 83593971 Common - hypothetical protein Rru_A2639 6 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83593392 Common - Molybdopterin-guanine dinucleotide biosynthesis MobB region Rru_A2057 107 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 83592819 Common - Asparagine synthase, glutamine-hydrolyzing Rru_A1483 160 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83592117 Common - Lipoprotein YaeC Rru_A0778 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 83594680 Common - Methionyl-tRNA formyltransferase Rru_A3351 214 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 83594806 Common - Major facilitator superfamily MFS_1 Rru_A3477 64 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83591541 Common - Endonuclease/exonuclease/phosphatase Rru_A0201 81 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 83592023 Common - hypothetical protein Rru_A0684 36 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 83592342 Common - Acyltransferase 3 Rru_A1006 12 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 83592950 Common - 3-mercaptopyruvate sulfurtransferase Rru_A1615 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 83591940 Common - Phosphate transport system permease protein 1 Rru_A0601 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 83593618 Common - Protein of unknown function DUF269 Rru_A2283 25 None None None 83591405 Common - Squalene/phytoene synthase Rru_A0065 77 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 83593575 Common - enoyl-CoA hydratase Rru_A2240 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83594830 Common - lipoprotein, putative Rru_A3501 17 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 83594668 Common - putative inner membrane protein translocase component YidC Rru_A3339 209 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 83591707 Common - NUDIX hydrolase Rru_A0367 121 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 83592666 Common - Malonate/sodium symporter MadM subunit Rru_A1330 11 COG2855 COG2855, Predicted membrane protein Function unknown 83593598 Common - ATPase, E1-E2 type Rru_A2263 209 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 83592517 Common - Cell division transporter substrate-binding protein FtsY Rru_A1181 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 83591343 Common recF recombination protein F Rru_A0003 85 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 83593701 Common - chemotaxis sensory transducer Rru_A2366 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592192 Nonpathogen - hypothetical protein Rru_A0856 2 None None None 83593122 Common - Cyclic nucleotide-binding domain (cNMP-BD) protein Rru_A1787 107 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83593875 Common - Major facilitator superfamily protein MFS_1 Rru_A2540 159 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83591357 Common - Bacitracin resistance protein BacA Rru_A0017 48 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 83592978 Common - Binding-protein-dependent transport systems inner membrane component Rru_A1643 133 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 83594495 Common - Histidinol-phosphate phosphatase, putative, inositol monophosphatase Rru_A3165 186 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 83593235 Common - Transcriptional Regulator, AsnC family Rru_A1900 141 COG1522 Lrp, Transcriptional regulators Transcription 83594665 Common - Ribosomal protein L34 Rru_A3336 188 None None None 83593312 Common - indolepyruvate oxidoreductase subunit B Rru_A1977 56 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 83591811 Common - Rod shape-determining protein MreC, subtype Rru_A0471 150 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 83594334 Common - Aminotransferase, class I and II Rru_A3004 181 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83591725 Common - Gamma-glutamyltransferase Rru_A0385 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 83592395 Common - Aldo/keto reductase Rru_A1059 203 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 83594332 Common - Nicotinamidase Rru_A3002 126 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 83592108 Common - extracellular solute-binding protein, family 1 Rru_A0769 106 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 83592528 Common - Ubiquinol-cytochrome c reductase, iron-sulfur subunit Rru_A1192 98 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 83592698 Common - Xylose isomerase-like TIM barrel Rru_A1362 8 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 83594134 Nonpathogen - Cytochrome c, class I Rru_A2802 1 COG2863 COG2863, Cytochrome c553 Energy production and conversion 83591568 Common - Twin-arginine translocation pathway signal Rru_A0228 63 COG2367 PenP, Beta-lactamase class A Defense mechanisms 83594293 Nonpathogen - hypothetical protein Rru_A2963 1 None None None 83593324 Common - Asparagine synthase, glutamine-hydrolyzing Rru_A1989 151 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83592089 Common - Peptide chain release factor 1 Rru_A0750 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 83594403 Common - Phosphoesterase, PA-phosphatase related Rru_A3073 21 COG3907 COG3907, PAP2 (acid phosphatase) superfamily protein General function prediction only 83594787 Common - GCN5-related N-acetyltransferase Rru_A3458 66 COG0456 RimI, Acetyltransferases General function prediction only 83592634 Common - ABC transporter component Rru_A1298 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 83591455 Nonpathogen - hypothetical protein Rru_A0115 1 None None None 83593731 Common - Putative FecR Rru_A2396 45 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 83593379 Nonpathogen - hypothetical protein Rru_A2044 4 None None None 83593051 Common - YeeE/YedE Rru_A1716 62 COG2391 COG2391, Predicted transporter component General function prediction only 83595111 Common rbfA ribosome-binding factor A Rru_A3782 130 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 83594236 Common - transposase Rru_A2904 35 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 83593651 Common - Transcriptional Regulator, XRE family Rru_A2316 52 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 83593740 Common - transketolase Rru_A2405 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 83593255 Common - ABC transporter component Rru_A1920 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83594257 Common - Major facilitator superfamily MFS_1 Rru_A2925 117 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 83591635 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Rru_A0295 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 83594579 Common - DSBA oxidoreductase Rru_A3249 84 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 83593369 Common - Phosphate transporter Rru_A2034 137 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 83593143 Nonpathogen - hypothetical protein Rru_A1808 1 None None None 83591496 Common - Secretion protein HlyD Rru_A0156 110 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83594622 Nonpathogen - hypothetical protein Rru_A3292 7 None None None 83592269 Common - DegT/DnrJ/EryC1/StrS aminotransferase Rru_A0933 191 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 83594855 Common - Protein of unknown function DUF167 Rru_A3526 58 COG1872 COG1872, Uncharacterized conserved protein Function unknown 83592041 Common - Molybdate ABC transporter, ATP-binding protein Rru_A0702 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 83592973 Common - putative monovalent cation/H+ antiporter subunit B Rru_A1638 29 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 83592110 Nonpathogen - hypothetical protein Rru_A0771 2 None None None 83592165 Common - CRISPR-associated CT1134 family protein Rru_A0829 38 None None None 83591654 Common - hydrogenase 4 subunit D Rru_A0314 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 83593302 Common - Peptidase S8 and S53, subtilisin, kexin, sedolisin Rru_A1967 20 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 83594341 Common - Isochorismatase hydrolase Rru_A3011 93 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 83592263 Common - luciferase-like Rru_A0927 107 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 83593439 Common - ABC transporter component Rru_A2104 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 83594866 Common - Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Rru_A3537 4 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 83592798 Common - Transcriptional Regulator, AraC family Rru_A1462 108 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83593779 Common - Transcriptional Regulator, TetR family Rru_A2444 72 COG1309 AcrR, Transcriptional regulator Transcription 83594685 Common - Polyhydroxyalkanoate depolymerase Rru_A3356 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 83592711 Common - hypothetical protein Rru_A1375 2 COG5373 COG5373, Predicted membrane protein Function unknown 83592348 Common - Nitrogenase molybdenum-iron protein beta chain Rru_A1012 55 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83593885 Common - L-carnitine dehydratase/bile acid-inducible protein F Rru_A2550 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 83593658 Common - Two component CheB methylesterase Rru_A2323 221 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 83591942 Common - Two component Transcriptional regulator, Winged helix family Rru_A0603 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83592098 Common - Aldo/keto reductase Rru_A0759 150 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 83591623 Common - hypothetical protein Rru_A0283 5 None None None 83594208 Common - Aldo/keto reductase Rru_A2876 190 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 83593584 Common - Threonine aldolase Rru_A2249 110 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 83594917 Common - Cytochrome B561 Rru_A3588 45 COG3658 COG3658, Cytochrome b Energy production and conversion 83592807 Common - Butyrate-acetoacetate CoA-transferase Rru_A1471 101 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 83592088 Common - Glutamyl-tRNA reductase Rru_A0749 179 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 83593823 Common - Putative RNA methylase Rru_A2488 22 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 83591809 Common - ketol-acid reductoisomerase Rru_A0469 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 83592500 Common - Peptidase M52, hydrogenase expression/formation protein Rru_A1164 65 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 83594178 Nonpathogen - hypothetical protein Rru_A2846 2 None None None 83592101 Common - Fe-S oxidoreductase Rru_A0762 111 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 83592859 Common - Nucleoside 2-deoxyribosyltransferase Rru_A1524 19 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 83592893 Common - NADH dehydrogenase subunit D Rru_A1558 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 83593282 Common - nucleotidyltransferase-like Rru_A1947 18 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 83592854 Nonpathogen - hypothetical protein Rru_A1519 2 None None None 83593223 Nonpathogen - Preprotein translocase SecG subunit Rru_A1888 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 83594839 Common - ABC transporter component Rru_A3510 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83593163 Common - Ribose 5-phosphate isomerase B Rru_A1828 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 83593397 Nonpathogen - hypothetical protein Rru_A2062 1 None None None 83594976 Nonpathogen - hypothetical protein Rru_A3647 1 None None None 83595108 Common nusA transcription elongation factor NusA Rru_A3779 222 COG0195 NusA, Transcription elongation factor Transcription 83592802 Common - Transcriptional Regulator, LysR family Rru_A1466 192 COG0583 LysR, Transcriptional regulator Transcription 83591464 Nonpathogen - Putative diguanylate phosphodiesterase (EAL domain) Rru_A0124 2 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83592865 Common - 5,10-methylenetetrahydrofolate reductase Rru_A1530 153 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 83592523 Common - tRNA (guanine-N(1)-)-methyltransferase Rru_A1187 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 83594249 Common - hypothetical protein Rru_A2917 23 None None None 83594462 Common - Putative diguanylate cyclase (GGDEF domain) with GAF sensor domain Rru_A3132 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83593513 Common - extracellular solute-binding protein, family 5 Rru_A2178 196 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 83593606 Common - HesB/YadR/YfhF Rru_A2271 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 83593470 Common mdoG glucan biosynthesis protein G Rru_A2135 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 83594832 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Rru_A3503 11 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 83594181 Common flgI flagellar basal body P-ring protein Rru_A2849 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 83593119 Common - exodeoxyribonuclease III xth Rru_A1784 195 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 83594654 Common - integral membrane protein linked to a cation pump-like Rru_A3325 23 COG5456 COG5456, Predicted integral membrane protein linked to a cation pump Inorganic ion transport and metabolism 83594025 Common rpsL 30S ribosomal protein S12 Rru_A2693 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 83592222 Common - Hydrophobe/amphiphile efflux-1 HAE1 Rru_A0886 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83592403 Common - Cobalamin synthesis protein/P47K Rru_A1067 41 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 83591853 Common - dihydroorotate dehydrogenase 2 Rru_A0514 232 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 83594387 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Rru_A3057 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83591821 Common - hypothetical protein Rru_A0481 3 None None None 83592145 Common - conjugal transfer protein Rru_A0806 22 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 83592262 Common - glycosidase Rru_A0926 30 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 83593428 Common - Methyltransferase FkbM Rru_A2093 38 None None None 161777626 Common kgd alpha-ketoglutarate decarboxylase Rru_A1213 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 83593817 Common - transcription regulator containing helix turn helix domain Rru_A2482 28 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 83592916 Common - GCN5-related N-acetyltransferase Rru_A1581 55 COG0456 RimI, Acetyltransferases General function prediction only 83595062 Common - HNH endonuclease Rru_A3733 102 COG1403 McrA, Restriction endonuclease Defense mechanisms 83592328 Nonpathogen - hypothetical protein Rru_A0992 1 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 83593457 Nonpathogen - hypothetical protein Rru_A2122 1 None None None 83591792 Common - Protein of unknown function DUF196 Rru_A0452 17 COG3512 COG3512, Uncharacterized protein conserved in bacteria Function unknown 83594229 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Rru_A2897 215 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83592056 Common - phage repressor Rru_A0717 31 COG2932 COG2932, Predicted transcriptional regulator Transcription 83591427 Common - hypothetical protein Rru_A0087 106 COG2081 COG2081, Predicted flavoproteins General function prediction only 83593182 Common - Transglutaminase-like Rru_A1847 105 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 83591544 Common - BolA-like protein Rru_A0204 73 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 83591920 Common - Three-deoxy-D-manno-octulosonic-acid transferase-like Rru_A0581 125 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 83593040 Common - Rare lipoprotein A Rru_A1705 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 83592742 Common - Two component CheB methylesterase Rru_A1406 203 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 83591724 Common - NADPH-quinone reductase Rru_A0384 158 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83591845 Common - Glycoside hydrolase Rru_A0506 166 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 83591883 Common fliG flagellar motor switch protein G Rru_A0544 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 83593789 Nonpathogen - hypothetical protein Rru_A2454 1 None None None 83594463 Nonpathogen - hypothetical protein Rru_A3133 1 None None None 83592147 Common - type II secretion system protein E Rru_A0808 145 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 83594127 Nonpathogen - hypothetical protein Rru_A2795 1 None None None 83594727 Common - Transcriptional Regulator, XRE family Rru_A3398 35 COG1396 HipB, Predicted transcriptional regulators Transcription 83593782 Common - Mammalian cell entry related Rru_A2447 55 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 83591738 Common - Thiol-disulfide isomerase and thioredoxins-like Rru_A0398 154 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 83593459 Common - Glycosyl transferase, family 2 Rru_A2124 185 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83592285 Common murC UDP-N-acetylmuramate--L-alanine ligase Rru_A0949 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 83594886 Common - hypothetical protein Rru_A3557 17 None None None 83592457 Common - pyruvate carboxylase Rru_A1121 240 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 83593604 Common - Pyruvate carboxyltransferase Rru_A2269 212 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 83594118 Common - inner-membrane translocator Rru_A2786 98 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 83592646 Common - Acetyl-CoA C-acyltransferase Rru_A1310 185 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 83593364 Common - Serine O-acetyltransferase Rru_A2029 190 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 83591772 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Rru_A0432 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 83592288 Common - UDP-N-acetylmuramoylalanine-D-glutamate ligase Rru_A0952 209 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 83592435 Common - Dihydropteroate synthase Rru_A1099 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 83592759 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A1423 109 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 83593080 Common - Single-strand binding protein Rru_A1745 207 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 83594498 Common - Binding-protein-dependent transport systems inner membrane component Rru_A3168 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 83593136 Common - hypothetical protein Rru_A1801 13 None None None 83594603 Nonpathogen - Protein of unknown function DUF1470 Rru_A3273 5 COG5516 COG5516, Conserved protein containing a Zn-ribbon-like motif, possibly RNA-binding General function prediction only 83594948 Common rho transcription termination factor Rho Rru_A3619 206 COG1158 Rho, Transcription termination factor Transcription 83594311 Common - 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide Rru_A2981 80 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 83593621 Common - Nitrogenase MoFe cofactor biosynthesis protein NifE Rru_A2286 54 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83592075 Common - hypothetical protein Rru_A0736 73 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83593467 Nonpathogen - hypothetical protein Rru_A2132 1 COG5164 SPT5, Transcription elongation factor Transcription 83594550 Common - TonB-dependent receptor Rru_A3220 122 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 83593986 Common - Acylphosphatase Rru_A2654 116 COG1254 AcyP, Acylphosphatases Energy production and conversion 83591604 Common - TPR repeat Rru_A0264 104 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83593075 Nonpathogen - hypothetical protein Rru_A1740 1 None None None 83593911 Nonpathogen - hypothetical protein Rru_A2579 1 None None None 83593647 Common - TonB-dependent receptor Rru_A2312 90 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 83591513 Common - hypothetical protein Rru_A0173 7 None None None 83591370 Common - hypothetical protein Rru_A0030 9 None None None 83594482 Nonpathogen - hypothetical protein Rru_A3152 1 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 83592207 Nonpathogen - hypothetical protein Rru_A0871 1 None None None 83591993 Common - multiple drug resistance protein MarC Rru_A0654 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 83592750 Common - regulatory protein GntR Rru_A1414 101 COG2186 FadR, Transcriptional regulators Transcription 83592787 Nonpathogen - hypothetical protein Rru_A1451 4 None None None 83591504 Common - Sulfate transporter/antisigma-factor antagonist Rru_A0164 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 83592380 Common - Peptide deformylase Rru_A1044 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 83592653 Common - Electron-transferring-flavoprotein dehydrogenase Rru_A1317 105 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 83592707 Nonpathogen - hypothetical protein Rru_A1371 1 None None None 83593355 Common - Plasmid maintenance system killer Rru_A2020 59 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 83592295 Common - MraZ protein Rru_A0959 108 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 83593861 Nonpathogen - hypothetical protein Rru_A2526 4 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 83591484 Common - NADH:flavin oxidoreductase/NADH oxidase Rru_A0144 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 83591366 Nonpathogen - hypothetical protein Rru_A0026 1 None None None 83592299 Nonpathogen - MifU-like protein, Fe-S cluster formation Rru_A0963 18 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 83594102 Common - hypothetical protein Rru_A2770 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 83591588 Common - inner-membrane translocator Rru_A0248 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 83593103 Common - Protein-L-isoaspartate(D-aspartate) O-methyltransferase Rru_A1768 157 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 83594523 Common - Glutathione S-transferase-like Rru_A3193 76 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83594906 Common - Protein of unknown function DUF6, transmembrane Rru_A3577 49 None None None 83594559 Common - Two Component Transcriptional Regulator, LuxR family Rru_A3229 179 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83593308 Common - Transcriptional Regulator, LacI family Rru_A1973 128 COG1609 PurR, Transcriptional regulators Transcription 83593285 Common - Transcriptional regulator, ModE family Rru_A1950 36 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 83594927 Common - Transcriptional Regulator, XRE family Rru_A3598 38 COG1396 HipB, Predicted transcriptional regulators Transcription 83592494 Common - Osmosensitive K+ channel Signal Transduction Histidine Kinase Rru_A1158 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 83594119 Common - inner-membrane translocator Rru_A2787 111 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 83595101 Common - hypothetical protein Rru_A3772 91 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 83592604 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Rru_A1268 153 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 83594474 Common - sulfite reductase Rru_A3144 64 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 83593687 Nonpathogen - hypothetical protein Rru_A2352 1 None None None 83592068 Common - Short-chain dehydrogenase/reductase SDR Rru_A0729 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 83592571 Common - Protein of unknown function DUF163 Rru_A1235 155 COG1576 COG1576, Uncharacterized conserved protein Function unknown 83593477 Common - chemotaxis sensory transducer Rru_A2142 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592690 Common - hypothetical protein Rru_A1354 5 None None None 83592706 Nonpathogen - hypothetical protein Rru_A1370 1 None None None 83594422 Nonpathogen - Parallel beta-helix repeat Rru_A3092 12 None None None 83594188 Common - putative flagellar protein FlaF Rru_A2856 16 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 83592232 Common - hypothetical protein Rru_A0896 15 None None None 83592581 Common - Transcriptional Regulator, Crp/Fnr family Rru_A1245 96 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83592175 Common - Transcriptional Regulator, AraC family Rru_A0839 27 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83592454 Common - Hydrophobe/amphiphile efflux-1 HAE1 Rru_A1118 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83592983 Common - Helix-turn-helix protein, CopG Rru_A1648 4 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 83593934 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Rru_A2602 152 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83592876 Common - beta alanine--pyruvate transaminase Rru_A1541 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 83594303 Common - Peptidase M16-like Rru_A2973 169 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 83592371 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Rru_A1035 183 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83592903 Common - NADH dehydrogenase subunit N Rru_A1568 208 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 83593592 Common - Transcriptional Regulator, LysR family Rru_A2257 137 COG0583 LysR, Transcriptional regulator Transcription 83593158 Common - 3,4-Dihydroxy-2-butanone 4-phosphate synthase Rru_A1823 231 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 83592462 Common - ISBm1, transposase orfA Rru_A1126 79 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83592884 Common tig trigger factor Rru_A1549 209 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 83593493 Common - Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family Rru_A2158 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83592596 Common - ABC transporter component Rru_A1260 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 83591652 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A0312 132 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 83592998 Common - Ubiquinol-cytochrome C chaperone Rru_A1663 22 COG5452 COG5452, Uncharacterized conserved protein Function unknown 83592103 Common - HesB/YadR/YfhF Rru_A0764 124 COG0316 IscA, Uncharacterized conserved protein Function unknown 83592135 Common - Radical SAM Rru_A0796 77 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 83592369 Common - Protein of unknown function DUF892 Rru_A1033 37 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 83593444 Common - ATP-dependent Clp protease ATP-binding subunit ClpA Rru_A2109 223 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 83591452 Nonpathogen - hypothetical protein Rru_A0112 5 None None None 83591838 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0498 177 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 83594433 Common - Multi-sensor Signal Transduction Histidine Kinase Rru_A3103 163 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83592464 Common - Integrase, catalytic region Rru_A1128 38 None None None 83591534 Nonpathogen - hypothetical protein Rru_A0194 4 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83594483 Common - conserved virulence factor protein Rru_A3153 14 COG4458 SrfC, Uncharacterized protein conserved in bacteria, putative virulence factor Function unknown 83592433 Common - PP-loop protein Rru_A1097 173 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 83592382 Common - AMP-dependent synthetase and ligase Rru_A1046 218 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 83591442 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A0102 175 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83591660 Common - NADH dehydrogenase (quinone) Rru_A0320 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 83592785 Common - Bile acid:sodium symporter Rru_A1449 125 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 83593199 Common smpB SsrA-binding protein Rru_A1864 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 83592389 Common - chemotaxis sensory transducer Rru_A1053 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83591579 Nonpathogen - hypothetical protein Rru_A0239 1 None None None 83593504 Common - Nucleoside-diphosphate kinase Rru_A2169 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 83591566 Common - Major facilitator superfamily MFS_1 Rru_A0226 79 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83592251 Common - hypothetical protein Rru_A0915 7 None None None 83593668 Common - chemotaxis sensory transducer Rru_A2333 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594826 Nonpathogen - Disulphide bond formation protein DsbB Rru_A3497 3 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 83591592 Common - Zinc-containing alcohol dehydrogenase superfamily Rru_A0252 212 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 83593274 Common - Pseudouridine synthase, Rsu Rru_A1939 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 83591951 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Rru_A0612 196 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83593017 Common - D-amino acid aminotransferase Rru_A1682 195 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 83592473 Common - transport system permease protein Rru_A1137 189 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 83591482 Common - Putative cyclase Rru_A0142 44 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 83592307 Common - hypothetical protein Rru_A0971 80 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 83591787 Common - AMMECR1 Rru_A0447 71 COG2078 AMMECR1, Uncharacterized conserved protein Function unknown 83594817 Common - Initiation factor 3 Rru_A3488 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 83594943 Common - Maf-like protein Rru_A3614 127 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 83593105 Common - Serine--tRNA ligase Rru_A1770 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 83593780 Common - Protein of unknown function DUF140 Rru_A2445 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 83594774 Common - Phosphoenolpyruvate-protein phosphotransferase Rru_A3445 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 83591570 Common - Asparagine synthase, glutamine-hydrolyzing Rru_A0230 173 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83592681 Common - hypothetical protein Rru_A1345 67 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 83593558 Common - branched-chain amino acid aminotransferase Rru_A2223 218 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 83594714 Common - OmpA/MotB Rru_A3385 20 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83594359 Common - D-fructose-6-phosphate amidotransferase Rru_A3029 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 83594082 Common - Secretion protein HlyD Rru_A2750 137 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83591612 Common - Small multidrug resistance protein Rru_A0272 61 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 83593661 Common - Response regulator receiver domain protein (CheY) Rru_A2326 223 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83594962 Nonpathogen - Thiamine monophosphate synthase Rru_A3633 1 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 83591473 Common - Glycosyl transferase, group 1 Rru_A0133 160 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83592205 Nonpathogen - hypothetical protein Rru_A0869 1 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 83594261 Common - Two component Transcriptional regulator, Winged helix family Rru_A2929 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83591414 Common - Helicase-like Rru_A0074 64 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 83594612 Common - hypothetical protein Rru_A3282 7 COG5590 COG5590, Uncharacterized conserved protein Function unknown 83595085 Common - PAS/PAC Sensor Hybrid Histidine Kinase Rru_A3756 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83594448 Common - Lipopolysaccharide biosynthesis Rru_A3118 56 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 83593854 Common - hypothetical protein Rru_A2519 38 COG0401 COG0401, Uncharacterized homolog of Blt101 Function unknown 83594804 Common - Fe-S metabolism associated SufE Rru_A3475 101 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 83592283 Common - D-alanine--D-alanine ligase Rru_A0947 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 83594028 Common rplL 50S ribosomal protein L7/L12 Rru_A2696 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 83592727 Nonpathogen - hypothetical protein Rru_A1391 7 None None None 83594848 Common - Transcriptional Regulator, MarR family Rru_A3519 29 COG1846 MarR, Transcriptional regulators Transcription 83591958 Common - Mg-protoporphyrin IX methyl transferase Rru_A0619 94 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83593685 Common - Methylase involved in ubiquinone/menaquinone biosynthesis-like Rru_A2350 14 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83593716 Common - lipocalin-like protein Rru_A2381 67 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 83591753 Common rpsR 30S ribosomal protein S18 Rru_A0413 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 83591441 Nonpathogen - hypothetical protein Rru_A0101 8 COG5381 COG5381, Uncharacterized protein conserved in bacteria Function unknown 83593923 Nonpathogen - hypothetical protein Rru_A2591 1 None None None 83595004 Common - Glutathione S-transferase-like Rru_A3675 72 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83593692 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2357 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83593245 Common - Cyclopropane-fatty-acyl-phospholipid synthase Rru_A1910 142 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 83592918 Common - chemotaxis sensory transducer Rru_A1583 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83591644 Common - Transcriptional Regulator, XRE family Rru_A0304 49 COG2944 COG2944, Predicted transcriptional regulator Transcription 83593759 Common - Gamma-glutamyltranspeptidase Rru_A2424 12 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 83594172 Common fliM flagellar motor switch protein FliM Rru_A2840 109 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 83594877 Common - Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase Rru_A3548 98 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 83594350 Nonpathogen - hypothetical protein Rru_A3020 2 None None None 83591919 Common - OsmC-like protein Rru_A0580 61 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 83593178 Common - OmpA/MotB Rru_A1843 87 COG1360 MotB, Flagellar motor protein Cell motility and secretion 83594313 Common - Polyprenyl synthetase Rru_A2983 235 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 83594281 Nonpathogen - hypothetical protein Rru_A2949 4 None None None 83592625 Common - Alkaline phosphatase Rru_A1289 84 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 83592930 Common - Outer membrane chaperone Skp (OmpH) Rru_A1595 16 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 83593162 Common - Glycine hydroxymethyltransferase Rru_A1827 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 83591972 Common - DNA polymerase III subunit epsilon Rru_A0633 75 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 83594214 Common - RNA polymerase sigma factor RpoD Rru_A2882 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 83593761 Nonpathogen - LrgA Rru_A2426 8 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 83594883 Common - Heat shock protein DnaJ Rru_A3554 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 83594230 Common - Thioredoxin reductase Rru_A2898 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 83593644 Common - NADH peroxidase Rru_A2309 240 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 83594164 Nonpathogen - hypothetical protein Rru_A2832 10 COG5373 COG5373, Predicted membrane protein Function unknown 83592209 Nonpathogen - hypothetical protein Rru_A0873 4 None None None 83592963 Nonpathogen - hypothetical protein Rru_A1628 9 None None None 83591674 Common - Transcriptional Regulator, LysR family Rru_A0334 180 COG0583 LysR, Transcriptional regulator Transcription 83592843 Common - short-chain dehydrogenase/reductase SDR Rru_A1507 181 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 83592553 Common pspB phage shock protein B Rru_A1217 8 None None None 83593526 Common - AMP-dependent synthetase and ligase Rru_A2191 215 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 83594395 Common - Transcriptional Regulator, XRE family Rru_A3065 45 COG2944 COG2944, Predicted transcriptional regulator Transcription 83593317 Common - SEC-C domain protein Rru_A1982 87 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 83591690 Common - Helix-turn-helix protein, CopG Rru_A0350 12 None None None 83593260 Common - regulatory protein GntR Rru_A1925 197 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83591843 Common - Peptidase M23B Rru_A0504 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83591926 Common groEL chaperonin GroEL Rru_A0587 244 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 83592948 Common - Cystathionine beta-lyase Rru_A1613 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 83593750 Nonpathogen - hypothetical protein Rru_A2415 1 None None None 83594234 Nonpathogen - hypothetical protein Rru_A2902 1 None None None 83595066 Common - KAP P-loop Rru_A3737 26 COG4928 COG4928, Predicted P-loop ATPase General function prediction only 83593677 Nonpathogen - hypothetical protein Rru_A2342 1 None None None 83594533 Common - ribonuclease R Rru_A3203 192 COG0557 VacB, Exoribonuclease R Transcription 83592254 Common - Histidine kinase Rru_A0918 105 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 83592034 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase Rru_A0695 208 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 83592379 Common rpsU 30S ribosomal protein S21 Rru_A1043 40 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 83594035 Common - RNA methyltransferase TrmH, group 3 Rru_A2703 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 83594580 Common - Protein of unknown function DUF1159 Rru_A3250 14 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 83592423 Common ruvC Holliday junction resolvase Rru_A1087 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 83593742 Common - GCN5-related N-acetyltransferase Rru_A2407 109 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 83594275 Common - permease YjgP/YjgQ Rru_A2943 119 COG0795 COG0795, Predicted permeases General function prediction only 83594216 Common - GatB/Yqey Rru_A2884 110 COG1610 COG1610, Uncharacterized conserved protein Function unknown 83591385 Common - Beta-ketoacyl synthase Rru_A0045 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83594005 Common rplF 50S ribosomal protein L6 Rru_A2673 231 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 83594552 Common - transport system permease protein Rru_A3222 169 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 83592032 Common - Signal Transduction Histidine Kinase Rru_A0693 90 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 83593294 Common - Radical SAM Rru_A1959 166 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 83595113 Common - Ribosomal protein S15 Rru_A3784 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 83593413 Common - chemotaxis sensory transducer Rru_A2078 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593546 Common - Porin, Gram-negative type Rru_A2211 4 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 83593948 Common - Histone deacetylase superfamily Rru_A2616 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 83592831 Common - hypothetical protein Rru_A1495 2 None None None 83593001 Common - fatty acid/phospholipid synthesis protein Rru_A1666 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 83592444 Nonpathogen - hypothetical protein Rru_A1108 2 None None None 83594730 Common - sulfate ABC transporter, permease protein CysT Rru_A3401 229 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 83594031 Common rplK 50S ribosomal protein L11 Rru_A2699 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 83594894 Common - Rhomboid-like protein Rru_A3565 148 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 83593975 Common - Glycerophosphoryl diester phosphodiesterase Rru_A2643 51 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 83593624 Common - sulfate adenylyltransferase subunit 2 Rru_A2289 134 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 83591697 Common - hypothetical protein Rru_A0357 128 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 83592644 Common - Acyl-CoA dehydrogenase Rru_A1308 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83594919 Nonpathogen - hypothetical protein Rru_A3590 4 None None None 83591761 Nonpathogen - hypothetical protein Rru_A0421 1 None None None 83594837 Common - inner-membrane translocator Rru_A3508 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 83592489 Common - Protein of unknown function DUF196 Rru_A1153 21 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83592314 Common - Transcriptional Regulator, MarR family Rru_A0978 26 COG1846 MarR, Transcriptional regulators Transcription 83592805 Common - Acetyl-CoA C-acetyltransferase Rru_A1469 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 83593570 Common - Multi-sensor Signal Transduction Histidine Kinase Rru_A2235 220 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 83593339 Common - Transcriptional Regulator, LysR family Rru_A2004 22 COG0583 LysR, Transcriptional regulator Transcription 83592424 Common - DNA recombination protein RuvA Rru_A1088 196 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 83591873 Nonpathogen - hypothetical protein Rru_A0534 3 None None None 83593560 Common - Two component Transcriptional regulator, Winged helix family Rru_A2225 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83591909 Common - Glutamate--cysteine ligase Rru_A0570 53 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 83592671 Common - inner-membrane translocator Rru_A1335 126 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 83594994 Common - chemotaxis sensory transducer Rru_A3665 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594096 Common - hypothetical protein Rru_A2764 90 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 83595020 Common - Transport-associated Rru_A3691 31 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 83591523 Nonpathogen - Cold-shock DNA-binding domain protein Rru_A0183 8 COG1278 CspC, Cold shock proteins Transcription 83594997 Common - hypothetical protein Rru_A3668 119 COG2606 EbsC, Uncharacterized conserved protein Function unknown 83594565 Common - Secretion protein HlyD Rru_A3235 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83595096 Common - Ferric uptake regulator (FUR) family Rru_A3767 196 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 83593910 Nonpathogen - hypothetical protein Rru_A2578 1 None None None 83594620 Common - Metallophosphoesterase Rru_A3290 61 COG1409 Icc, Predicted phosphohydrolases General function prediction only 83592399 Common - putative transcription regulator protein Rru_A1063 41 COG0583 LysR, Transcriptional regulator Transcription 83595023 Common - hypothetical protein Rru_A3694 26 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83594720 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A3391 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83591904 Nonpathogen - hypothetical protein Rru_A0565 1 None None None 83592613 Common - Hpt Sensor Hybrid Histidine Kinase Rru_A1277 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83592768 Common - Nicotinate-nucleotide pyrophosphorylase Rru_A1432 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 83591659 Common - NADH-ubiquinone oxidoreductase, chain 4L Rru_A0319 13 COG4237 HyfE, Hydrogenase 4 membrane component (E) Energy production and conversion 83594982 Common - Protein of unknown function DUF214 Rru_A3653 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 83595048 Common - Methyltransferase FkbM Rru_A3719 53 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 83593766 Common - Protein of unknown function DUF1078 Rru_A2431 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 83595059 Common - asparaginase Rru_A3730 25 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 83592213 Common - hypothetical protein Rru_A0877 49 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 83592334 Common - NifT/FixU Rru_A0998 16 COG5554 NifU, Nitrogen fixation protein Secondary metabolites biosynthesis, transport, and catabolism 83594459 Common - ABC-2 transporter component Rru_A3129 148 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 83593896 Nonpathogen - hypothetical protein Rru_A2561 5 None None None 83594067 Nonpathogen - hypothetical protein Rru_A2735 3 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 83591669 Nonpathogen - hypothetical protein Rru_A0329 1 None None None 83594924 Common - Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Rru_A3595 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 83593721 Common - hypothetical protein Rru_A2386 8 None None None 83594905 Common - UDP-glucuronate 5'-epimerase Rru_A3576 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83592714 Common - Phosphate acetyltransferase Rru_A1378 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 83592544 Common - AFG1-like ATPase Rru_A1208 102 COG1485 COG1485, Predicted ATPase General function prediction only 83592620 Common - Cytoplasmic chaperone TorD Rru_A1284 14 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 83591914 Common - Peptidase U62, modulator of DNA gyrase Rru_A0575 167 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 83594955 Common - Glucose inhibited division protein Rru_A3626 190 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 83592058 Common - hypothetical protein Rru_A0719 11 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83594294 Common - MaoC-like dehydratase Rru_A2964 77 COG2030 MaoC, Acyl dehydratase Lipid metabolism 83594091 Common - hydroxylamine reductase Rru_A2759 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 83594607 Common - Acetylornithine and succinylornithine aminotransferase Rru_A3277 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 83591599 Common - Carbon starvation protein CstA Rru_A0259 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 83594742 Common - ABC transporter component Rru_A3413 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83593917 Nonpathogen - hypothetical protein Rru_A2585 2 None None None 83592568 Common - C-terminal processing peptidase S41A Rru_A1232 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 83594227 Common - Twin-arginine translocation pathway signal Rru_A2895 154 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 83592015 Common - Transposase IS116/IS110/IS902 Rru_A0676 62 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 83593349 Common - Twin-arginine translocation pathway signal Rru_A2014 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 83591863 Common - MCP methyltransferase, CheR-type Rru_A0524 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 83591894 Common - Nitrogen regulatory protein P-II (GlnB, GlnK) Rru_A0555 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 83594755 Common - hypothetical protein Rru_A3426 41 COG4949 COG4949, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 83592701 Common - ribose ABC transporter, periplasmic binding protein Rru_A1365 92 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83591398 Common - Dihydrokaempferol 4-reductase Rru_A0058 127 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83593955 Common - chorismate synthase Rru_A2623 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 83593866 Nonpathogen - hypothetical protein Rru_A2531 1 None None None 83592952 Common - Protein of unknown function DUF1289 Rru_A1617 23 COG3313 COG3313, Predicted Fe-S protein General function prediction only 83593903 Common - FeS assembly protein SufD Rru_A2571 169 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 83591930 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0591 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83591935 Common - fructose-1,6-bisphosphate aldolase Rru_A0596 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 83593215 Common - pyruvate dehydrogenase subunit beta Rru_A1880 215 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 83592860 Common - Nucleoside diphosphate pyrophosphatase Rru_A1525 78 COG4119 COG4119, Predicted NTP pyrophosphohydrolase DNA replication, recombination, and repair / General function prediction only 83591436 Common - Secretion protein HlyD Rru_A0096 95 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83593835 Common - Rhodanese-like Rru_A2500 45 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 83594627 Nonpathogen - hypothetical protein Rru_A3297 1 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 83593797 Common - Enzymatic protein of unknown function Rru_A2462 67 COG2170 COG2170, Uncharacterized conserved protein Function unknown 83594144 Common - molybdopterin-guanine dinucleotide biosynthesis protein A Rru_A2812 78 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 83591796 Common - Predicted transcriptional regulator Rru_A0456 39 COG3636 COG3636, Predicted transcriptional regulator Transcription 83594703 Common - Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain Rru_A3374 187 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83595015 Common - Alanine dehydrogenase and pyridine nucleotide transhydrogenase Rru_A3686 162 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 83594782 Common - ABC transporter component Rru_A3453 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 83594549 Common - Twin-arginine translocation pathway signal Rru_A3219 39 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 83594584 Common - ABC transporter component Rru_A3254 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 83593770 Common - acetyl-CoA carboxylase biotin carboxylase subunit Rru_A2435 227 COG0439 AccC, Biotin carboxylase Lipid metabolism 83593310 Common - Transcriptional Regulator, XRE family Rru_A1975 15 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 83592362 Common - Transcriptional Regulator, MerR family Rru_A1026 136 COG0789 SoxR, Predicted transcriptional regulators Transcription 83594120 Common - cytosine deaminase Rru_A2788 78 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 83592167 Common - CRISPR-associated TM1801 family protein Rru_A0831 52 COG3649 COG3649, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83593719 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2384 129 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 83595128 Common - DNA-formamidopyrimidine glycosylase Rru_A3799 177 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 83592160 Common - Cupin region Rru_A0823 19 COG2850 COG2850, Uncharacterized conserved protein Function unknown 83593145 Nonpathogen - hypothetical protein Rru_A1810 2 None None None 83592632 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Rru_A1296 168 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83593530 Common - Bacterioferritin Rru_A2195 106 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 83593410 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Rru_A2075 213 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 83592211 Nonpathogen - hypothetical protein Rru_A0875 1 None None None 83594624 Nonpathogen - KaiB Rru_A3294 1 None None None 83591684 Common - CRISPR-associated CT1975 family protein Rru_A0344 42 None None None 83593455 Common - Acyl transferase region Rru_A2120 63 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83591759 Common - Aminodeoxychorismate lyase Rru_A0419 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 83593733 Common - Pyruvate-ferredoxin (flavodoxin) oxidoreductase Rru_A2398 123 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 83594198 Common - Ribosomal protein L11 methyltransferase Rru_A2866 160 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 83593768 Common - 3-dehydroquinate dehydratase Rru_A2433 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 83591498 Common - chemotaxis sensory transducer Rru_A0158 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594577 Nonpathogen - hypothetical protein Rru_A3247 2 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 83591902 Common - Twin-arginine translocation pathway signal Rru_A0563 113 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83592386 Common - Phosphoribosylaminoimidazole carboxylase Rru_A1050 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 83591528 Common - ABC transporter, transmembrane region Rru_A0188 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83592265 Nonpathogen - hypothetical protein Rru_A0929 1 None None None 83595123 Common - Cysteine synthase Rru_A3794 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 83593825 Common - Transcriptional Regulator, AraC family Rru_A2490 70 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83594808 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase Rru_A3479 146 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 83592837 Common - Transport-associated Rru_A1501 38 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 83593657 Common - CheW protein Rru_A2322 130 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83593124 Common - Cytochrome-c peroxidase Rru_A1789 93 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 83593883 Common - hypothetical protein Rru_A2548 44 None None None 83594766 Common - Aminoglycoside phosphotransferase Rru_A3437 90 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 83594914 Common - Phosphatidylserine decarboxylase-related protein Rru_A3585 90 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 83591424 Common - Peptidase S33, proline iminopeptidase 1 Rru_A0084 100 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83594596 Common metX homoserine O-acetyltransferase Rru_A3266 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 83593482 Common - Penicillin-binding protein 1A Rru_A2147 202 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 83594259 Common - Acriflavin resistance protein Rru_A2927 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83594419 Nonpathogen - hypothetical protein Rru_A3089 1 None None None 83592310 Common - Linocin_M18 bacteriocin protein Rru_A0974 18 COG1659 COG1659, Uncharacterized protein, linocin/CFP29 homolog Function unknown 83594971 Common hrcA heat-inducible transcription repressor Rru_A3642 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 83593313 Common - indolepyruvate ferredoxin oxidoreductase Rru_A1978 108 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 83593436 Common - Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family Rru_A2101 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83591368 Common - Beta-lactamase-like Rru_A0028 67 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83592957 Common - Transcriptional Regulator, Crp/Fnr family Rru_A1622 117 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83594682 Common - Small multidrug resistance protein Rru_A3353 147 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 83591884 Common fliF flagellar MS-ring protein Rru_A0545 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 83593586 Common - extracellular solute-binding protein, family 3 Rru_A2251 172 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83593353 Common - hypothetical protein Rru_A2018 17 COG1598 COG1598, Uncharacterized conserved protein Function unknown 83592086 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Rru_A0747 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 83592713 Common - hypothetical protein Rru_A1377 2 None None None 83594540 Common - DNA methylase N-4/N-6 Rru_A3210 138 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 83591412 Common - heat shock protein 90 Rru_A0072 151 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 83593304 Common - Esterase, PHB depolymerase Rru_A1969 33 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 83594206 Common - FAD dependent oxidoreductase Rru_A2874 129 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 83593777 Common - Transcriptional Regulator, XRE family Rru_A2442 15 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 83593320 Nonpathogen - hypothetical protein Rru_A1985 1 None None None 83593878 Common - KaiB Rru_A2543 25 None None None 83593814 Common - methylmalonyl-CoA mutase Rru_A2479 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 83594176 Common flgA flagellar basal body P-ring biosynthesis protein FlgA Rru_A2844 50 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 83593633 Common - hypothetical protein Rru_A2298 17 None None None 83591892 Common - Response Regulator Receiver Signal Transduction Histidine Kinase Rru_A0553 217 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 83592981 Common - ETC complex I subunit conserved region Rru_A1646 36 None None None 83594329 Common - Radical SAM Rru_A2999 107 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 83592793 Common - O-methyltransferase, family 2 Rru_A1457 24 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 83592502 Common - hydrogenase expression/formation protein hupH Rru_A1166 19 None None None 83593259 Nonpathogen - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family-like Rru_A1924 4 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 83594343 Common - Binding-protein-dependent transport systems inner membrane component Rru_A3013 175 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 83593102 Common - peptidase M23B Rru_A1767 196 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 83594491 Nonpathogen - hypothetical protein Rru_A3161 1 None None None 83594157 Common flgC flagellar basal body rod protein FlgC Rru_A2825 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 83591494 Common - Dihydrodipicolinate reductase Rru_A0154 212 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 83593960 Common - Cation efflux protein Rru_A2628 215 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 83593489 Common - Biopolymer transport protein ExbD/TolR Rru_A2154 143 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 83591489 Common - PfkB Rru_A0149 164 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 83593511 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2176 217 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83591870 Nonpathogen - hypothetical protein Rru_A0531 2 None None None 83593020 Common - Small GTP-binding protein domain Rru_A1685 216 COG2262 HflX, GTPases General function prediction only 83594966 Common - GTP cyclohydrolase II Rru_A3637 180 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 83591917 Common - Metallophosphoesterase Rru_A0578 62 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 83594634 Common - ABC transporter component Rru_A3304 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83592397 Common - Helix-turn-helix protein, CopG Rru_A1061 12 None None None 83594204 Common - L-2-amino-thiazoline-4-carboxylic acid hydrolase Rru_A2872 8 None None None 83594812 Common - Major facilitator superfamily MFS_1 Rru_A3483 48 None None None 83592356 Common - Cytochrome c, class I Rru_A1020 46 COG3474 COG3474, Cytochrome c2 Energy production and conversion 83593407 Common aspS aspartyl-tRNA synthetase Rru_A2072 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83594105 Common - hypothetical protein Rru_A2773 9 None None None 83592297 Common - hypothetical protein Rru_A0961 72 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 83591766 Nonpathogen - hypothetical protein Rru_A0426 1 None None None 83594489 Common - General substrate transporter Rru_A3159 153 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 83591648 Common - Hydrogenase maturation protein HypF Rru_A0308 111 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 83591403 Common - Amine oxidase Rru_A0063 42 COG3349 COG3349, Uncharacterized conserved protein Function unknown 83594385 Common - hypothetical protein Rru_A3055 33 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83593390 Common - Peptidase S49 Rru_A2055 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 83592115 Common - hypothetical protein Rru_A0776 233 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83594834 Common - ABC transporter component Rru_A3505 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83593969 Common - hypothetical protein Rru_A2637 16 COG5610 COG5610, Predicted hydrolase (HAD superfamily) General function prediction only 83591722 Common - Transcriptional Regulator, MerR family Rru_A0382 96 COG0789 SoxR, Predicted transcriptional regulators Transcription 83593197 Nonpathogen - hypothetical protein Rru_A1862 1 None None None 83595031 Common - ABC transporter component Rru_A3702 240 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 83592479 Common - regulatory protein GntR Rru_A1143 205 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 83592623 Common - Trimethylamine-N-oxide reductase (cytochrome c) Rru_A1287 177 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 83593990 Common - haloacid dehalogenase-like hydrolase Rru_A2658 188 COG0546 Gph, Predicted phosphatases General function prediction only 83591600 Common - Protein of unknown function DUF466 Rru_A0260 26 COG2879 COG2879, Uncharacterized small protein Function unknown 83591355 Common - 3'-5' exonuclease Rru_A0015 99 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 83591790 Common - Uncharacterized protein predicted to be involved in DNA repair-like Rru_A0450 19 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83594722 Common - Penicillin-binding protein 1A Rru_A3393 201 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 83595038 Common - Protein of unknown function DUF343 Rru_A3709 78 COG2835 COG2835, Uncharacterized conserved protein Function unknown 83593384 Common - Transcriptional Regulator, TetR family Rru_A2049 81 COG1309 AcrR, Transcriptional regulator Transcription 83593465 Common - Lysine exporter protein (LYSE/YGGA) Rru_A2130 96 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83592880 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A1545 165 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83593360 Common - Transcriptional activator, TenA family Rru_A2025 71 COG0819 TenA, Putative transcription activator Transcription 83591731 Nonpathogen - hypothetical protein Rru_A0391 3 None None None 83594267 Common - PAS/PAC Sensor Hybrid Histidine Kinase Rru_A2935 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83593997 Common - 30S ribosomal protein S11 Rru_A2665 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 83592194 Common - Drug resistance transporter EmrB/QacA subfamily Rru_A0858 193 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83591747 Common - ABC transporter component Rru_A0407 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 83592095 Common - hypothetical protein Rru_A0756 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 83593617 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A2282 29 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 83592449 Common - Mov34/MPN/PAD-1 Rru_A1113 28 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 83592988 Common - guanylate cyclase (GGDEF domain) with PAS/PAC sensor and Response Regulator Receiver modulation Rru_A1653 186 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83591770 Common - Ribonuclease BN Rru_A0430 92 COG1295 Rbn, Predicted membrane protein Function unknown 83593058 Common - hypothetical protein Rru_A1723 29 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 83594503 Common - Transcriptional Regulator, TetR family Rru_A3173 24 COG1309 AcrR, Transcriptional regulator Transcription 83591715 Common - Pirin-like Rru_A0375 143 COG1741 COG1741, Pirin-related protein General function prediction only 83594984 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Rru_A3655 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 83592106 Common - ABC transporter component Rru_A0767 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 83594414 Common engA GTP-binding protein EngA Rru_A3084 235 COG1160 COG1160, Predicted GTPases General function prediction only 83593253 Common - Binding-protein-dependent transport systems inner membrane component Rru_A1918 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83592782 Common - Protein of unknown function DUF892 Rru_A1446 36 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 83591469 Nonpathogen - hypothetical protein Rru_A0129 1 None None None 83593334 Common - hypothetical protein Rru_A1999 13 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 83594112 Common - hypothetical protein Rru_A2780 19 COG5564 COG5564, Predicted TIM-barrel enzyme, possibly a dioxygenase General function prediction only 83593460 Nonpathogen - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family-like Rru_A2125 3 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 83592077 Common - Glutaredoxin, GrxC Rru_A0738 140 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 83593340 Common - Glutaryl-CoA dehydrogenase Rru_A2005 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83591732 Common - Molybdopterin binding domain Rru_A0392 165 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 83593900 Common - HesB/YadR/YfhF Rru_A2568 163 COG0316 IscA, Uncharacterized conserved protein Function unknown 83592731 Common nifH nitrogenase reductase Rru_A1395 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 83593689 Common - adenylate cyclase Rru_A2354 87 COG3025 COG3025, Uncharacterized conserved protein Function unknown 83591477 Common - TRAP transporter solute receptor, TAXI family Rru_A0137 87 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 83595073 Common - Predicted signal-transduction protein containing CBS domains Rru_A3744 152 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 83593233 Common - LexA repressor Rru_A1898 168 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 83592578 Common - Ribosomal protein L21 Rru_A1242 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 83591779 Common - extracellular solute-binding protein, family 3 Rru_A0439 78 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83593209 Nonpathogen - hypothetical protein Rru_A1874 1 None None None 83591515 Common - CRISPR-associated helicase Cas3, core Rru_A0175 71 COG1203 COG1203, Predicted helicases General function prediction only 83594454 Common - Alpha/beta hydrolase fold Rru_A3124 19 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 83591502 Common groEL chaperonin GroEL Rru_A0162 246 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 83594525 Common - Helix-turn-helix protein, CopG Rru_A3195 14 COG4710 COG4710, Predicted DNA-binding protein with an HTH domain General function prediction only 83594716 Common - Acetyl-CoA C-acetyltransferase Rru_A3387 168 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 83591662 Common - Peptidase M52, hydrogen uptake protein Rru_A0322 28 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 83592131 Common - Serine O-acetyltransferase Rru_A0792 188 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 83592275 Common - DNA ligase (NAD+) Rru_A0939 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 83593907 Common - hypothetical protein Rru_A2575 3 COG5373 COG5373, Predicted membrane protein Function unknown 83591606 Common - Phage SPO1 DNA polymerase-related protein Rru_A0266 155 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 83593045 Nonpathogen - Prevent-host-death protein Rru_A1710 5 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 83592752 Common - hypothetical protein Rru_A1416 7 None None None 83593225 Common - hypothetical protein Rru_A1890 109 None None None 83595055 Common - inner-membrane translocator Rru_A3726 157 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 83592709 Common - Peptidase C14, caspase catalytic subunit p20 Rru_A1373 14 None None None 83594469 Common - Transcriptional Regulator, GntR family Rru_A3139 116 COG1802 GntR, Transcriptional regulators Transcription 83592812 Common - PhnA protein Rru_A1476 100 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 83591586 Common - Ppx/GppA phosphatase Rru_A0246 178 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 83594055 Nonpathogen - Rubrerythrin Rru_A2723 8 COG1633 COG1633, Uncharacterized conserved protein Function unknown 83592800 Common - HPr kinase Rru_A1464 7 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 83592840 Common - hypothetical protein Rru_A1504 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 83592293 Common - secreted (periplasmic) protein-like Rru_A0957 16 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 83593707 Common - Sigma-24 (FecI) Rru_A2372 108 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83593287 Common - Fusaric acid resistance protein conserved region Rru_A1952 47 COG1289 COG1289, Predicted membrane protein Function unknown 83592749 Common - Protein of unknown function DUF224, cysteine-rich region Rru_A1413 170 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 83592336 Common - hypothetical protein Rru_A1000 8 None None None 83594605 Common - Hsp33 protein Rru_A3275 128 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 83594671 Common - Dihydrodipicolinate synthase subfamily Rru_A3342 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 83592492 Common - Potassium-translocating P-type ATPase B subunit Rru_A1156 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 83592879 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Rru_A1544 196 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83593792 Common - Endoribonuclease L-PSP Rru_A2457 89 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 83591384 Nonpathogen - acyl carrier protein Rru_A0044 1 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83594104 Common hisG ATP phosphoribosyltransferase catalytic subunit Rru_A2772 207 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 83591828 Common - TonB-dependent receptor Rru_A0488 124 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 83594933 Nonpathogen - hypothetical protein Rru_A3604 2 None None None 83592975 Common - Multiple resistance and pH regulation protein F Rru_A1640 22 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 83592245 Common - Propanediol utilization protein Rru_A0909 36 COG4869 PduL, Propanediol utilization protein Secondary metabolites biosynthesis, transport, and catabolism 83592485 Nonpathogen - Protein of unknown function DUF324 Rru_A1149 3 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 83591625 Common - Aldehyde dehydrogenase Rru_A0285 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83593976 Nonpathogen - hypothetical protein Rru_A2644 1 None None None 83592525 Common - isopropylmalate isomerase large subunit Rru_A1189 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 83594810 Nonpathogen - hypothetical protein Rru_A3481 3 None None None 83592913 Common - Lipoprotein releasing system, transmembrane protein, LolC/E family Rru_A1578 171 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 83594393 Common - Crotonyl-CoA reductase Rru_A3063 183 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83592946 Common - Cobalamin synthesis protein/P47K Rru_A1611 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 83592157 Common - HPr kinase Rru_A0820 17 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 83592143 Common - Transcriptional Regulator, LysR family Rru_A0804 138 COG0583 LysR, Transcriptional regulator Transcription 83592436 Common - Phosphoglucosamine mutase Rru_A1100 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 83592373 Common - Amidohydrolase Rru_A1037 53 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 83594460 Common - ABC transporter component Rru_A3130 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83592470 Common - Cation transporter Rru_A1134 123 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 83593042 Nonpathogen - hypothetical protein Rru_A1707 1 None None None 83592668 Common - Cobalt transport protein Rru_A1332 39 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 83593174 Common - TRAP-type C4-dicarboxylate transport system periplasmic component-like Rru_A1839 15 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 83593278 Common - Propionyl-CoA carboxylase Rru_A1943 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 83591945 Common - Transcriptional Regulator, LysR family Rru_A0606 158 COG0583 LysR, Transcriptional regulator Transcription 83593775 Common - NADH dehydrogenase Rru_A2440 38 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 83592401 Common - Plasmid maintenance system antidote protein Rru_A1065 69 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 83592990 Common - Hemerythrin HHE cation binding region Rru_A1655 50 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 83593202 Common - Protein of unknown function DUF583 Rru_A1867 78 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 161777624 Common - bifunctional sulfur carrier protein/thiazole synthase protein Rru_A2432 169 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 83593845 Nonpathogen - hypothetical protein Rru_A2510 2 None None None 83593540 Common - Protein of unknown function DUF1321 Rru_A2205 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 83593981 Common - extracellular endo alpha-1 4 polygalactosaminidase or related polysaccharide hydrolase-like Rru_A2649 7 COG2342 COG2342, Predicted extracellular endo alpha-1,4 polygalactosaminidase or related polysaccharide hydrolase Carbohydrate transport and metabolism 83592125 Common - Cystathionine gamma-synthase Rru_A0786 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 83593927 Common - hypothetical protein Rru_A2595 5 COG3610 COG3610, Uncharacterized conserved protein Function unknown 83592419 Common - Protein of unknown function DUF710 Rru_A1083 27 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 83592540 Common sdhA succinate dehydrogenase flavoprotein subunit Rru_A1204 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 83593714 Nonpathogen - Rubrerythrin Rru_A2379 2 COG1633 COG1633, Uncharacterized conserved protein Function unknown 83594370 Common - Aminotransferase, class V Rru_A3040 69 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 83594735 Common - Carboxylesterase Rru_A3406 93 COG0627 COG0627, Predicted esterase General function prediction only 83593331 Common lipB lipoyltransferase Rru_A1996 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 83592777 Common - Transcriptional Regulator, MarR family Rru_A1441 103 COG1846 MarR, Transcriptional regulators Transcription 83593535 Common - DNA polymerase III subunit chi Rru_A2200 50 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 83592054 Common - Mg2+ transporter protein, CorA-like Rru_A0715 41 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 83593089 Common - hypothetical protein Rru_A1754 31 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 83592321 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A0985 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83594978 Common - 2',5' RNA ligase Rru_A3649 121 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 83591711 Common - Double-transmembrane region-like Rru_A0371 31 None None None 83593180 Common - arginyl-tRNA-protein transferase Rru_A1845 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 83594023 Common - Translation elongation factor G Rru_A2691 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 83593250 Common - DEAD/DEAH box helicase Rru_A1915 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 83593327 Common - Arsenate reductase Rru_A1992 106 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 83593415 Nonpathogen - hypothetical protein Rru_A2080 2 None None None 83593800 Common - Pyruvate kinase Rru_A2465 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 83592856 Common - Cold-shock DNA-binding domain protein Rru_A1521 178 COG1278 CspC, Cold shock proteins Transcription 83594365 Common - nuclease (SNase-like) Rru_A3035 18 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 83591462 Nonpathogen - hypothetical protein Rru_A0122 1 None None None 83592459 Common - YbaK/prolyl-tRNA synthetase associated region Rru_A1123 30 COG3760 COG3760, Uncharacterized conserved protein Function unknown 83593696 Common - Multi-sensor Hybrid Histidine Kinase Rru_A2361 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83593566 Common - Glycosyl transferase, family 25 Rru_A2231 30 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 83591847 Common - aminotransferase Rru_A0508 180 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 83594316 Common - tricarballylate dehydrogenase Rru_A2986 33 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 83592740 Common - chemotaxis sensory transducer Rru_A1404 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594480 Common - ABC transporter component Rru_A3150 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83592795 Nonpathogen - Major facilitator superfamily MFS_1 Rru_A1459 1 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83593065 Common - nuclease Rru_A1730 20 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 83593752 Common - Lipoprotein YaeC Rru_A2417 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 83592721 Common - acetoacetate metabolism regulatory protein AtoC Rru_A1385 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83592542 Nonpathogen - hypothetical protein Rru_A1206 1 None None None 83593169 Common - Enoyl-CoA hydratase/isomerase Rru_A1834 130 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83594536 Common - Response regulator receiver domain protein (CheY) Rru_A3206 223 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 83593268 Common - Uroporphyrin-III C-methyltransferase Rru_A1933 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 83594296 Common ileS isoleucyl-tRNA synthetase Rru_A2966 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83592515 Common - Transcriptional Regulator, DeoR family Rru_A1179 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 83594614 Common - Secretion chaperone CsaA Rru_A3284 129 COG0073 ARC1, EMAP domain General function prediction only 83591475 Common - molybdenum ABC transporter ATP-binding protein Rru_A0135 18 None None None 83591552 Nonpathogen - hypothetical protein Rru_A0212 2 None None None 83593501 Nonpathogen - hypothetical protein Rru_A2166 3 None None None 83594870 Common - DNA mismatch repair protein Rru_A3541 198 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 83594820 Nonpathogen - hypothetical protein Rru_A3491 1 None None None 83591573 Nonpathogen - hypothetical protein Rru_A0233 5 None None None 83594026 Common - DNA-directed RNA polymerase Rru_A2694 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 83592203 Common - Peptidase C14, caspase catalytic subunit p20 Rru_A0867 17 None None None 83592300 Common - Protein of unknown function DUF182 Rru_A0964 76 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 83594911 Common - Protein of unknown function DUF1025 Rru_A3582 49 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 83593133 Common - Type I secretion outer membrane protein, TolC Rru_A1798 146 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83593856 Common - DNA helicase, putative Rru_A2521 87 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 83593276 Common - acyl-CoA carboxylase alpha chain Rru_A1941 222 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 83594987 Common - Glycosyl transferase, group 1 Rru_A3658 143 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83593988 Common - ATP12 ATPase Rru_A2656 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 83594953 Common trmE tRNA modification GTPase TrmE Rru_A3624 217 COG0486 ThdF, Predicted GTPase General function prediction only 83592309 Common - hypothetical protein Rru_A0973 25 COG3461 COG3461, Uncharacterized conserved protein Function unknown 83594964 Common - hypothetical protein Rru_A3635 42 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 83593921 Common - hypothetical protein Rru_A2589 10 None None None 83591638 Common - Aldehyde dehydrogenase (NAD+) Rru_A0298 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83592833 Common - Cyclic peptide transporter Rru_A1497 248 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 83594219 Common - GreA/GreB family elongation factor Rru_A2887 204 COG0782 GreA, Transcription elongation factor Transcription 83594318 Common - Precorrin-6X reductase Rru_A2988 72 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 83591956 Nonpathogen - Photosynthetic reaction center, H-chain Rru_A0617 9 None None None 83592606 Common - hypothetical protein Rru_A1270 28 COG4717 COG4717, Uncharacterized conserved protein Function unknown 83592968 Nonpathogen - hypothetical protein Rru_A1633 2 None None None 83592019 Common - hypothetical protein Rru_A0680 5 None None None 83594137 Common - Protein of unknown function DUF214 Rru_A2805 27 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 83592258 Common - Protein of unknown function DUF1044 Rru_A0922 24 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 83593795 Common - chemotaxis sensory transducer Rru_A2460 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594212 Common - hypothetical protein Rru_A2880 79 COG2898 COG2898, Uncharacterized conserved protein Function unknown 83592935 Common - Citrate synthase I Rru_A1600 194 COG0372 GltA, Citrate synthase Energy production and conversion 83591432 Common - extracellular solute-binding protein, family 1 Rru_A0092 72 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83593373 Common - Glutamate-ammonia-ligase adenylyltransferase Rru_A2038 221 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 83594796 Common - Amidinotransferase Rru_A3467 28 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 83591924 Common - ABC transporter component Rru_A0585 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83594875 Common - Glutamine amidotransferase of anthranilate synthase Rru_A3546 227 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 83593319 Nonpathogen - nitrogen fixation-related protein Rru_A1984 12 COG1433 COG1433, Uncharacterized conserved protein Function unknown 83592123 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Rru_A0784 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 83591681 Common - hypothetical protein Rru_A0341 5 None None None 83592845 Common - hypothetical protein Rru_A1509 5 None None None 83593524 Common - TRm3 transposase Rru_A2189 43 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 83592238 Common - Peptidase C56, PfpI Rru_A0902 124 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 83594372 Nonpathogen - hypothetical protein Rru_A3042 1 None None None 83594003 Common rpsE 30S ribosomal protein S5 Rru_A2671 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 83593627 Nonpathogen - hypothetical protein Rru_A2292 1 None None None 83593594 Nonpathogen - hypothetical protein Rru_A2259 1 None None None 83594420 Common - Glycosyl transferase, family 2 Rru_A3090 145 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83594435 Common - glycosyl transferases group 1 Rru_A3105 67 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83593942 Common - hypothetical protein Rru_A2610 46 None None None 83592460 Common - D-lactate dehydrogenase (cytochrome) Rru_A1124 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83592346 Common nifH nitrogenase reductase Rru_A1010 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 83592052 Common - Protein of unknown function DUF833 Rru_A0713 46 COG3332 COG3332, Uncharacterized conserved protein Function unknown 83592874 Common - Molybdenum-pterin binding protein Rru_A1539 69 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 83593882 Common - N-formylglutamate amidohydrolase Rru_A2547 54 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 83592996 Common - Extensin-like Rru_A1661 38 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 83592673 Common - ABC transporter component Rru_A1337 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 83593666 Nonpathogen - hypothetical protein Rru_A2331 2 None None None 83592905 Common - pantothenate kinase Rru_A1570 140 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 83591868 Nonpathogen - hypothetical protein Rru_A0529 1 None None None 83591704 Common - ubiquinol-cytochrome c reductase, iron-sulfur subunit Rru_A0364 100 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 83594582 Common - dTDP-glucose 4,6-dehydratase Rru_A3252 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83592220 Common - Putative FecR Rru_A0884 43 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 83591450 Nonpathogen - hypothetical protein Rru_A0110 1 None None None 83592181 Common - TonB-dependent siderophore receptor Rru_A0845 109 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 83593857 Common - hypothetical protein Rru_A2522 78 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 83592466 Common - Nitrogen regulatory protein P-II (GlnB, GlnK) Rru_A1130 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 83593421 Common - Glutamine synthetase type I Rru_A2086 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 83592417 Nonpathogen - hypothetical protein Rru_A1081 1 None None None 83591789 Common - Radical SAM Rru_A0449 87 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 83594609 Nonpathogen - Protein of unknown function DUF526 Rru_A3279 1 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 83594060 Nonpathogen - NnrU Rru_A2728 8 COG4094 COG4094, Predicted membrane protein Function unknown 83591807 Common - Acetolactate synthase, large subunit, biosynthetic type Rru_A0467 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 83591855 Common - GCN5-related N-acetyltransferase Rru_A0516 33 COG3153 COG3153, Predicted acetyltransferase General function prediction only 83592716 Common - Acetyl-CoA C-acetyltransferase Rru_A1380 170 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 83593498 Common - hypothetical protein Rru_A2163 83 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 83593446 Nonpathogen - hypothetical protein Rru_A2111 1 None None None 83593013 Common - Nitrogen Metabolism Transcriptional Regulator, NtrC, Fis Family Rru_A1678 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83591977 Nonpathogen - hypothetical protein Rru_A0638 14 None None None 83591671 Common - Protein of unknown function DUF6, transmembrane Rru_A0331 141 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83591803 Common - Alanine racemase-like Rru_A0463 60 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 83594535 Common - Ribosomal protein L33 Rru_A3205 126 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 83591400 Common - Radical SAM Rru_A0060 118 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 83595098 Common - Phospholipid/glycerol acyltransferase Rru_A3769 115 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 83592814 Common - HPr kinase Rru_A1478 18 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 83593850 Common - extracellular solute-binding protein, family 3 Rru_A2515 82 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83591439 Common - Serine phosphatase Rru_A0099 114 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 83593599 Common - ferredoxin Rru_A2264 36 COG2440 FixX, Ferredoxin-like protein Energy production and conversion 83593156 Common - NusB antitermination factor Rru_A1821 115 COG0781 NusB, Transcription termination factor Transcription 83593678 Common - Protein of unknown function DUF83 Rru_A2343 38 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 83592561 Common - F0F1 ATP synthase subunit gamma Rru_A1225 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 83591646 Common - Hydrogenase formation HypD protein Rru_A0306 108 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 83591382 Nonpathogen - hypothetical protein Rru_A0042 1 None None None 83591984 Common - ribose-phosphate pyrophosphokinase Rru_A0645 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 83594129 Nonpathogen - hypothetical protein Rru_A2797 1 None None None 83592555 Common - Sigma54 Specific Transcriptional Regulator containing PAS, and Fis DNA-binding domains Rru_A1219 168 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 83591614 Common - Acetyl-CoA C-acetyltransferase Rru_A0274 172 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 83591372 Common - TPR repeat Rru_A0032 38 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 83591717 Common - Signal Transduction Histidine Kinase (STHK), LytS Rru_A0377 105 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 83592642 Common - short chain dehydrogenase Rru_A1306 229 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83594691 Common - Uroporphyrin-III C-methyltransferase-like Rru_A3362 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 83594560 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Rru_A3230 106 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83594763 Common - UvrD/REP helicase Rru_A3434 208 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 83592304 Common - ATPase associated with various cellular activities, AAA_5 Rru_A0968 93 COG0714 COG0714, MoxR-like ATPases General function prediction only 83594922 Common - Phosphoribosyl-ATP pyrophosphohydrolase Rru_A3593 174 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 83593622 Common - Protein of unknown function DUF86 Rru_A2287 52 COG2361 COG2361, Uncharacterized conserved protein Function unknown 83595057 Common - Extracellular ligand-binding receptor Rru_A3728 149 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83594701 Common - tRNA/rRNA methyltransferase (SpoU) Rru_A3372 65 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 161777628 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Rru_A0711 166 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 83592017 Common - Multi antimicrobial extrusion protein MatE Rru_A0678 112 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 83594745 Common - inner-membrane translocator Rru_A3416 108 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 83595080 Common - Argininosuccinate synthase Rru_A3751 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 83591369 Common - hypothetical protein Rru_A0029 5 None None None 83591459 Nonpathogen - Protein of unknown function DUF1328 Rru_A0119 1 None None None 83595036 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 Rru_A3707 132 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 83594729 Common - Thiosulphate-binding protein Rru_A3400 89 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 83594159 Common - hypothetical protein Rru_A2827 83 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 83591525 Nonpathogen - hypothetical protein Rru_A0185 1 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 83593864 Common - Protein of unknown function DUF1078 Rru_A2529 82 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 83594903 Common - Rieske (2Fe-2S) region Rru_A3574 25 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 83593638 Common - Deoxyribose-phosphate aldolase Rru_A2303 136 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 83593833 Common - ABC transporter component Rru_A2498 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83591912 Common - hypothetical protein Rru_A0573 31 COG3897 COG3897, Predicted methyltransferase General function prediction only 83595041 Common - Lysine exporter protein (LYSE/YGGA) Rru_A3712 30 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83592959 Nonpathogen - hypothetical protein Rru_A1624 1 None None None 83591861 Common - Response regulator receiver domain protein (CheY) Rru_A0522 220 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83594017 Common rplB 50S ribosomal protein L2 Rru_A2685 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 83594757 Common - Tryptophan synthase Rru_A3428 212 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 83594516 Common - hypothetical protein Rru_A3186 5 COG3212 COG3212, Predicted membrane protein Function unknown 83593690 Nonpathogen - hypothetical protein Rru_A2355 1 None None None 83594629 Common - Glycoside hydrolase, family 3-like Rru_A3299 100 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 83591794 Common - leucyl aminopeptidase Rru_A0454 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 83591768 Common - hypothetical protein Rru_A0428 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 83594554 Common - hypothetical protein Rru_A3224 21 None None None 83593247 Common - Short-chain dehydrogenase/reductase SDR Rru_A1912 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83594093 Common - Acyltransferase 3 Rru_A2761 123 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 83594780 Nonpathogen - hypothetical protein Rru_A3451 1 None None None 83594322 Common - Precorrin-6Y C5,15-methyltransferase (decarboxylating) Rru_A2992 105 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 83593737 Common - Ribulose-phosphate 3-epimerase Rru_A2402 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 83594225 Common - ABC-3 transporter component Rru_A2893 184 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 83591532 Common - Multi antimicrobial extrusion protein MatE Rru_A0192 160 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 83593915 Nonpathogen - hypothetical protein Rru_A2583 1 None None None 83593953 Common - Peptidase S49 Rru_A2621 188 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 83593034 Common - Beta-lactamase-like Rru_A1699 70 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 83593901 Common - Protein of unknown function DUF59 Rru_A2569 147 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 83593342 Common - Protein of unknown function DUF6, transmembrane Rru_A2007 81 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83594052 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A2720 112 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 83592611 Common - hypothetical protein Rru_A1275 22 None None None 83591663 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A0323 156 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 83592248 Common - Ethanolamine utilization protein EutN/carboxysome structural protein Ccml Rru_A0912 37 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 83592079 Common - Protein of unknown function DUF1178 Rru_A0740 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 83593309 Common - hypothetical protein Rru_A1974 60 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 83594515 Nonpathogen - hypothetical protein Rru_A3185 1 None None None 83592761 Common - NADH dehydrogenase (ubiquinone) Rru_A1425 192 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 83594352 Nonpathogen - hypothetical protein Rru_A3022 2 None None None 83594941 Common - Dephospho-CoA kinase Rru_A3612 170 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 83595013 Common - Sulfotransferase Rru_A3684 42 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83593191 Common - (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA Rru_A1856 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 83594151 Common - RecA DNA recombination protein Rru_A2819 227 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 83593816 Common - hypothetical protein Rru_A2481 32 COG4680 COG4680, Uncharacterized protein conserved in bacteria Function unknown 83594776 Common - PTS system fructose subfamily IIA component Rru_A3447 99 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 83594879 Common - cobyric acid synthase Rru_A3550 151 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 83595007 Common - TRAP dicarboxylate transporter- DctP subunit Rru_A3678 106 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 83593744 Common glpX fructose 1,6-bisphosphatase II Rru_A2409 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 83594084 Common - Signal Transduction Histidine Kinase Rru_A2752 92 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 83592895 Common - NADH-quinone oxidoreductase, F subunit Rru_A1560 162 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 83592030 Common - Predicted signal transduction protein Rru_A0691 160 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 83595060 Common - Transcriptional Regulator, GntR family Rru_A3731 137 COG1802 GntR, Transcriptional regulators Transcription 83594642 Common - Resolvase-like Rru_A3312 15 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 83594232 Common - Protein of unknown function DUF6, transmembrane Rru_A2900 144 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83594098 Common - Protein of unknown function DUF329 Rru_A2766 40 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 83593589 Nonpathogen - hypothetical protein Rru_A2254 1 None None None 83594593 Common - cyclohexadienyl dehydrogenase Rru_A3263 168 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 83591836 Common - Cyclic nucleotide-binding domain (cNMP-BD) protein Rru_A0496 132 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83594649 Common - Cytidyltransferase-related Rru_A3320 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 83594174 Common - hypothetical protein Rru_A2842 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 83593389 Nonpathogen - Hpt domain protein Rru_A2054 1 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 83594567 Common - RND efflux system, outer membrane lipoprotein, NodT Rru_A3237 118 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83593148 Common - Peptidase M20D, amidohydrolase Rru_A1813 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 83594881 Nonpathogen - hypothetical protein Rru_A3552 3 None None None 83593763 Common - DSBA oxidoreductase Rru_A2428 114 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 83591826 Common bchD magnesium chelatase subunit D Rru_A0486 69 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 83592446 Common - RNA polymerase factor sigma-32 Rru_A1110 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 83591539 Common - hypothetical protein Rru_A0199 8 None None None 83591963 Nonpathogen - 2-vinyl bacteriochlorophyllide hydratase Rru_A0624 14 None None None 83593699 Common - Hemimethylated DNA-binding region Rru_A2364 44 COG3785 COG3785, Uncharacterized conserved protein Function unknown 83594277 Nonpathogen - hypothetical protein Rru_A2945 1 None None None 83592482 Common - 5-aminolevulinate synthase Rru_A1146 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 83594239 Common - Anti-Sigma-factor antagonist (STAS) domain protein Rru_A2907 31 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 83594892 Common - chemotaxis sensory transducer Rru_A3563 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593160 Common - bifunctional deaminase-reductase Rru_A1825 224 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 83591341 Common dnaA chromosomal replication initiation protein Rru_A0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 83593292 Common - ExsB Rru_A1957 176 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 83594828 Common - hypothetical protein Rru_A3499 6 None None None 83592312 Common - Transcriptional modulator of MazE/toxin, MazF Rru_A0976 24 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 83592426 Common - 4-hydroxybenzoyl-CoA thioesterase Rru_A1090 130 COG0824 FcbC, Predicted thioesterase General function prediction only 83591907 Common - chemotaxis sensory transducer Rru_A0568 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593153 Common hppA membrane-bound proton-translocating pyrophosphatase Rru_A1818 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 83594283 Nonpathogen - hypothetical protein Rru_A2951 1 None None None 83594240 Common - Protein of unknown function DUF140 Rru_A2908 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 83594007 Common rpsN 30S ribosomal protein S14 Rru_A2675 210 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 83594195 Common - Transcriptional Regulator, TetR family Rru_A2863 87 COG1309 AcrR, Transcriptional regulator Transcription 83591692 Common - RepA Rru_A0352 32 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 83592683 Common - Transcriptional Regulator, GntR family Rru_A1347 133 COG1802 GntR, Transcriptional regulators Transcription 83593003 Common - Integration host factor, alpha subunit Rru_A1668 197 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 83594167 Nonpathogen - hypothetical protein Rru_A2835 1 None None None 83593631 Common - Protein of unknown function DUF165 Rru_A2296 49 COG1738 COG1738, Uncharacterized conserved protein Function unknown 83594939 Common - preprotein translocase subunit SecB Rru_A3610 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 83591934 Common - transketolase Rru_A0595 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 83591699 Common - Class II aldolase/adducin-like Rru_A0359 154 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 83592003 Common - Signal Transduction Histidine Kinase Rru_A0664 112 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 83592803 Common - Acetate kinase Rru_A1467 162 COG0282 ackA, Acetate kinase Energy production and conversion 83594284 Common - Methyltransferase small Rru_A2952 50 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 83593508 Common - Leucyl aminopeptidase Rru_A2173 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 83592839 Common - Zinc-containing alcohol dehydrogenase superfamily Rru_A1503 194 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 83593562 Common - GCN5-related N-acetyltransferase Rru_A2227 57 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 83594764 Common - hypothetical protein Rru_A3435 45 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 83594999 Common - Potassium efflux system protein Rru_A3670 200 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 83594099 Common - ribonuclease G (RNase G) Rru_A2767 165 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 83591961 Common - light-independent protochlorophyllide reductase subunit B Rru_A0622 29 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83593695 Common dppF dipeptide transporter ATP-binding subunit Rru_A2360 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 83591931 Common - extracellular solute-binding protein, family 5 Rru_A0592 213 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 83592615 Common - Asparagine synthase Rru_A1279 52 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83592427 Common - MotA/TolQ/ExbB proton channel Rru_A1091 149 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 83592060 Common - Anti-Sigm factor, ChrR Rru_A0721 31 COG3806 ChrR, Transcriptional activator Transcription 83595025 Common - Exodeoxyribonuclease III xth Rru_A3696 194 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 83593248 Nonpathogen - hypothetical protein Rru_A1913 1 None None None 83594519 Nonpathogen - hypothetical protein Rru_A3189 1 None None None 83594000 Common secY preprotein translocase subunit SecY Rru_A2668 224 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 83594758 Common - hypothetical protein Rru_A3429 4 None None None 83594187 Common - hypothetical protein Rru_A2855 116 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 83592810 Common - Protein of unknown function DUF1446 Rru_A1474 37 None None None 83593393 Common - Histidine Kinase Rru_A2058 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83592013 Common - Phage integrase Rru_A0674 41 None None None 83595009 Common - Integral membrane protein TerC Rru_A3680 96 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 83594241 Common - ABC transporter component Rru_A2909 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 83592021 Common - Glutathione reductase Rru_A0682 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 83593574 Common - TRAP dicarboxylate transporter- DctP subunit Rru_A2239 104 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 83593978 Nonpathogen - Hemerythrin HHE cation binding region Rru_A2646 3 None None None 83593346 Common - ABC transporter component Rru_A2011 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 83594733 Common - trkA-C domain protein Rru_A3404 75 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 83594168 Nonpathogen - hypothetical protein Rru_A2836 9 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592428 Common - Biopolymer transport protein ExbD/TolR Rru_A1092 142 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 83595053 Common - ABC transporter component Rru_A3724 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83594959 Common - Twin-arginine translocation pathway signal Rru_A3630 7 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 83593211 Common - cyclase/dehydrase Rru_A1876 103 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 83594152 Common - Multi-sensor Hybrid Histidine Kinase Rru_A2820 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83592317 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0981 223 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83592541 Common sdhB succinate dehydrogenase iron-sulfur subunit Rru_A1205 192 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 83592609 Common - Alpha/beta hydrolase fold Rru_A1273 117 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83593330 Common - Divalent cation transporter Rru_A1995 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 83593881 Common - chemotaxis sensory transducer Rru_A2546 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593943 Nonpathogen - hypothetical protein Rru_A2611 2 None None None 83594286 Common glyQ glycyl-tRNA synthetase subunit alpha Rru_A2954 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 83593201 Common - Lytic transglycosylase, catalytic Rru_A1866 161 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 83593615 Nonpathogen - hypothetical protein Rru_A2280 6 None None None 83592675 Common - Transcriptional Regulator, DeoR family Rru_A1339 69 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 83594510 Common - Metal dependent phosphohydrolase, HD region Rru_A3180 121 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 83594038 Nonpathogen - Ankyrin Rru_A2706 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 83593005 Nonpathogen - hypothetical protein Rru_A1670 1 None None None 83593869 Common - Flagellin-like Rru_A2534 128 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 83592765 Nonpathogen - hypothetical protein Rru_A1429 2 None None None 83591915 Common - chemotaxis sensory transducer Rru_A0576 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593786 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A2451 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83595130 Common - Enoyl-CoA hydratase/isomerase Rru_A3801 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83594648 Common - xanthine-guanine phosphoribosyltransferase Rru_A3319 78 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 83593352 Nonpathogen - hypothetical protein Rru_A2017 1 None None None 83591451 Nonpathogen - hypothetical protein Rru_A0111 1 None None None 83594882 Nonpathogen - hypothetical protein Rru_A3553 12 COG5302 COG5302, Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid General function prediction only 83592986 Common - hypothetical protein Rru_A1651 54 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83594298 Common - hypothetical protein Rru_A2968 15 None None None 83591694 Common - Phage integrase Rru_A0354 115 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 83593999 Common - Adenylate kinase, subfamily Rru_A2667 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 83595071 Common - CBS Rru_A3742 217 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 83591830 Common - transport system permease protein Rru_A0490 178 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 83592360 Common - phage repressor Rru_A1024 41 COG2932 COG2932, Predicted transcriptional regulator Transcription 83593132 Common - hypothetical protein Rru_A1797 17 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 83592637 Common - Histidine ammonia-lyase Rru_A1301 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 83593848 Common - Acetyl-CoA hydrolase/transferase Rru_A2513 99 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 83592048 Common - Phosphoribosylformylglycinamidine synthase I Rru_A0709 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 83594314 Common - CrtD protein Rru_A2984 77 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83592036 Common - Multi antimicrobial extrusion protein MatE Rru_A0697 136 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 83595091 Common - D-alanyl-D-alanine dipeptidase Rru_A3762 58 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 83592685 Common - Gamma-glutamyltransferase Rru_A1349 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 83593643 Common - Transcriptional Regulator, ArsR family Rru_A2308 95 COG0640 ArsR, Predicted transcriptional regulators Transcription 83592179 Common - ABC transporter component Rru_A0843 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83591816 Common - OsmC-like protein Rru_A0476 94 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 83591348 Nonpathogen - hypothetical protein Rru_A0008 1 None None None 83593039 Common - Serine-type D-Ala-D-Ala carboxypeptidase Rru_A1704 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 83594146 Common - Molybdopterin converting factor, subunit 1 Rru_A2814 71 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 83592306 Common - hypothetical protein Rru_A0970 97 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 83592028 Common cysS cysteinyl-tRNA synthetase Rru_A0689 243 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83593905 Common - cysteine desulfurase activator complex subunit SufB Rru_A2573 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 83594260 Common - Secretion protein HlyD Rru_A2928 137 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83594224 Common - ABC-3 transporter component Rru_A2892 186 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 83593367 Common - Tyrosyl-tRNA synthetase, class Ib Rru_A2032 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83593484 Common - Ribonuclease E and G Rru_A2149 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 83591538 Nonpathogen - hypothetical protein Rru_A0198 1 None None None 83591679 Common - short chain dehydrogenase Rru_A0339 206 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83593216 Common - Pyruvate dehydrogenase (lipoamide) Rru_A1881 160 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 83591777 Common - OmpA family protein Rru_A0437 148 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83593527 Common - Peptidase M3B, oligoendopeptidase-related clade 3 Rru_A2192 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 83591576 Common - Camphor resistance CrcB protein Rru_A0236 114 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 83592921 Common rpsB 30S ribosomal protein S2 Rru_A1586 217 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 83592440 Common - phosphoserine aminotransferase Rru_A1104 60 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 83593538 Common - HflK Rru_A2203 147 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 83592834 Nonpathogen - hypothetical protein Rru_A1498 1 None None None 83594190 Common - Flagellin-like Rru_A2858 81 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 83594196 Nonpathogen - Predicted signal transduction protein containing EFhand domain Rru_A2864 2 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 83593139 Common - N-acetyltransferase Rru_A1804 152 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 83592004 Common - Response regulator receiver domain protein (CheY) Rru_A0665 205 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83594589 Common - ChaC-like protein Rru_A3259 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 83593839 Common - coproporphyrinogen III oxidase Rru_A2504 202 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 83592006 Common - Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase Rru_A0667 117 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 83593473 Nonpathogen - hypothetical protein Rru_A2138 1 None None None 83593333 Common - ribulose-bisphosphate carboxylase-like protein; rubisco-like protein Rru_A1998 51 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 83593893 Common - Transglutaminase-like Rru_A2558 91 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 83594088 Nonpathogen - hypothetical protein Rru_A2756 1 None None None 83592530 Common - Protein of unknown function DUF134 Rru_A1194 40 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 83594746 Common - Extracellular ligand-binding receptor Rru_A3417 114 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83591448 Nonpathogen - Peptidase A24A, prepilin type IV Rru_A0108 1 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 83593315 Common - Protein of unknown function DUF1022 Rru_A1980 21 COG3660 COG3660, Predicted nucleoside-diphosphate-sugar epimerase Cell envelope biogenesis, outer membrane 83593745 Common - Homoserine dehydrogenase Rru_A2410 196 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 83594901 Common - YciI-like protein Rru_A3572 54 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 83594346 Common - Aminoglycoside phosphotransferase Rru_A3016 44 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 83595003 Nonpathogen - hypothetical protein Rru_A3674 1 None None None 83592964 Common - hypothetical protein Rru_A1629 23 None None None 83592170 Common - Protein of unknown function DUF196 Rru_A0834 46 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83594455 Common - Glycosyl transferase, group 1 Rru_A3125 173 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83592864 Common - Transcriptional Regulator, ArsR family Rru_A1529 143 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83591910 Common - hypothetical protein Rru_A0571 121 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 83594778 Common - HPr kinase Rru_A3449 31 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 83592569 Common - Peptidase M23B Rru_A1233 130 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 83593830 Common - Glycosyl transferase, family 2 Rru_A2495 166 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83594707 Common - hypothetical protein Rru_A3378 74 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83592600 Common - Short-chain dehydrogenase/reductase SDR Rru_A1264 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83591879 Common - Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family Rru_A0540 171 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83591584 Common - IMP dehydrogenase Rru_A0244 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 83594279 Common - Glucose-6-phosphate isomerase Rru_A2947 190 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 83591569 Common - Glycosyl transferase, group 1 Rru_A0229 43 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83591655 Common - NADH dehydrogenase (quinone) Rru_A0315 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 83594094 Common - hypothetical protein Rru_A2762 10 None None None 83592872 Nonpathogen - hypothetical protein Rru_A1537 1 None None None 83593852 Common - AMP-dependent synthetase and ligase Rru_A2517 201 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83592128 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0789 147 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 83592438 Common - Phosphomethylpyrimidine kinase Rru_A1102 215 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 83591378 Common - Cytochrome c-type biogenesis protein CcmC Rru_A0038 113 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 83593579 Common - Glycogen/starch/alpha-glucan phosphorylase Rru_A2244 140 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 83593601 Common - Electron transfer flavoprotein Rru_A2266 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 83593683 Common - Glycosyl transferase Rru_A2348 151 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 83594304 Common - Photosynthetic reaction centre M subunit Rru_A2974 21 None None None 83592564 Common - hypothetical protein Rru_A1228 10 None None None 83591617 Nonpathogen - hypothetical protein Rru_A0277 1 None None None 83591634 Common - Cytidylate kinase Rru_A0294 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 83591741 Common - hypothetical protein Rru_A0401 7 None None None 83592291 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase Rru_A0955 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 83591799 Nonpathogen - hypothetical protein Rru_A0459 1 None None None 83593015 Common - Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family Rru_A1680 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83592366 Common - Amino acid permease-associated region Rru_A1030 130 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 83594960 Common - Leucyl-tRNA synthetase, class Ia Rru_A3631 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83591908 Common - Chorismate mutase Rru_A0569 32 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 83594846 Common - Major facilitator superfamily MFS_1 Rru_A3517 61 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83592815 Nonpathogen - hypothetical protein Rru_A1479 1 None None None 83593195 Common - Uracil-DNA glycosylase superfamily Rru_A1860 98 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 83594354 Nonpathogen - Prolyl 4-hydroxylase, alpha subunit Rru_A3024 7 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 83593522 Common - Serine/Threonine protein kinase Rru_A2187 88 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 83594069 Common - Glycosyl transferase, family 2 Rru_A2737 169 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83594452 Nonpathogen - hypothetical protein Rru_A3122 13 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83594874 Common - Na+/H+ antiporter Rru_A3545 106 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 83594265 Nonpathogen - hypothetical protein Rru_A2933 1 None None None 83594072 Common - UDP-N-acetylglucosamine 2-epimerase Rru_A2740 150 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 83593551 Nonpathogen - Protein of unknown function DUF1127 Rru_A2216 1 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 83592513 Common - chemotaxis sensory transducer Rru_A1177 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593925 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A2593 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83593899 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A2567 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83594373 Nonpathogen - hypothetical protein Rru_A3043 1 None None None 83594719 Common - hypothetical protein Rru_A3390 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 83592355 Common - FAD dependent oxidoreductase Rru_A1019 104 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 83594693 Common - hypothetical protein Rru_A3364 18 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 83592113 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Rru_A0774 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 83593126 Common - ABC-2 transporter component Rru_A1791 141 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 83594821 Common - Periplasmic Sensor Hybrid Histidine Kinase Rru_A3492 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83592384 Common - Protein of unknown function DUF465 Rru_A1048 40 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 83592182 Nonpathogen - hypothetical protein Rru_A0846 1 None None None 83591857 Common - molybdenum cofactor biosynthesis protein Rru_A0518 195 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 83594799 Nonpathogen - hypothetical protein Rru_A3470 1 None None None 83591670 Common - Transcriptional Regulator, LysR family Rru_A0330 118 COG0583 LysR, Transcriptional regulator Transcription 83592657 Common - Biotin--acetyl-CoA-carboxylase ligase Rru_A1321 223 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 83593665 Common - Response regulator receiver domain protein (CheY) Rru_A2330 220 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 83592719 Common - Acetate CoA-transferase Rru_A1383 93 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 83591804 Nonpathogen - hypothetical protein Rru_A0464 1 None None None 83591800 Common - NADP oxidoreductase, coenzyme F420-dependent Rru_A0460 45 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 83591562 Common - Glyceraldehyde-3-phosphate dehydrogenase, type I Rru_A0222 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 83593060 Common - Carbonate dehydratase Rru_A1725 52 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 83593056 Common - Isochorismatase hydrolase Rru_A1721 107 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 83594619 Nonpathogen - Diacylglycerol kinase, catalytic region Rru_A3289 8 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 83593932 Common - Protein of unknown function DUF451 Rru_A2600 29 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 83592469 Common - excinuclease ABC subunit B Rru_A1133 226 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 83594646 Nonpathogen - hypothetical protein Rru_A3317 2 None None None 83593096 Common - GCN5-related N-acetyltransferase Rru_A1761 22 COG0456 RimI, Acetyltransferases General function prediction only 83591929 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0590 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83593859 Common - Peptidase U32 Rru_A2524 48 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 83592598 Common - extracellular solute-binding protein, family 1 Rru_A1262 87 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83594626 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Rru_A3296 218 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 83591435 Common - ABC transporter component Rru_A0095 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 83593547 Common - hypothetical protein Rru_A2212 7 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 83594407 Common - Electron transfer flavoprotein beta-subunit Rru_A3077 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 83594986 Common - Glycosyl transferase, family 4 Rru_A3657 126 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 83594135 Common - putative thioredoxin Rru_A2803 140 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83592302 Common - Carbon-monoxide dehydrogenase Rru_A0966 108 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 83594912 Common - ATP-dependent protease-like Rru_A3583 91 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 83594969 Common - putative deoxyribonucleotide triphosphate pyrophosphatase Rru_A3640 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 83593076 Nonpathogen - Phage integrase Rru_A1741 6 None None None 83592847 Common - Glycosyl transferase, family 2 Rru_A1511 72 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83594710 Common - cobyric acid synthase Rru_A3381 150 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 83591980 Common - Prolipoprotein diacylglyceryl transferase Rru_A0641 206 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 83592767 Common - Transcriptional Regulator, Crp/Fnr family Rru_A1431 82 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83593469 Nonpathogen - hypothetical protein Rru_A2134 1 None None None 83591627 Nonpathogen - hypothetical protein Rru_A0287 1 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 83593507 Common - hypothetical protein Rru_A2172 7 None None None 83594538 Nonpathogen - Protein of unknown function DUF29 Rru_A3208 2 None None None 83593790 Nonpathogen - hypothetical protein Rru_A2455 1 None None None 83593166 Common - hypothetical protein Rru_A1831 51 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 83591781 Common - chemotaxis sensory transducer Rru_A0441 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594297 Common - Peptidase A8, signal peptidase II Rru_A2967 193 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83592338 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Rru_A1002 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83591481 Common - delta-aminolevulinic acid dehydratase Rru_A0141 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 83593803 Nonpathogen - FeoA Rru_A2468 1 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 83591598 Common - Peptidase M48, Ste24p Rru_A0258 99 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 83591556 Common - Transcriptional Regulator, AsnC family Rru_A0216 145 COG1522 Lrp, Transcriptional regulators Transcription 83591691 Common - hypothetical protein Rru_A0351 46 None None None 83593387 Common - RND efflux system, outer membrane lipoprotein, NodT Rru_A2052 123 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83593920 Nonpathogen - hypothetical protein Rru_A2588 1 None None None 83593735 Common - Ribulose-bisphosphate carboxylase, form II Rru_A2400 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 83593370 Common - phosphate binding protein, putative Rru_A2035 84 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 83593448 Common - Serine-type D-Ala-D-Ala carboxypeptidase Rru_A2113 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 83593754 Common - ABC transporter component Rru_A2419 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 83593069 Nonpathogen - hypothetical protein Rru_A1734 1 None None None 83593500 Common - CDP-alcohol phosphatidyltransferase Rru_A2165 178 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 83595114 Common - polynucleotide phosphorylase/polyadenylase Rru_A3785 234 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 83594130 Nonpathogen - hypothetical protein Rru_A2798 1 None None None 83594444 Common - Polysaccharide deacetylase Rru_A3114 104 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 83592374 Common - Patatin Rru_A1038 80 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 83594438 Common - NAD-dependent epimerase/dehydratase Rru_A3108 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83592944 Nonpathogen - hypothetical protein Rru_A1609 1 None None None 83593764 Common - Plasmid maintenance system killer Rru_A2429 26 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 83592324 Nonpathogen - outer membrane protein Rru_A0988 1 None None None 83592794 Common - TonB-dependent receptor Rru_A1458 96 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 83592406 Common - Heat shock protein Hsp20 Rru_A1070 66 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 83594193 Common - hypothetical protein Rru_A2861 16 COG4627 COG4627, Uncharacterized protein conserved in bacteria Function unknown 83593189 Common - pyridoxal phosphate biosynthetic protein PdxJ Rru_A1854 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 83592792 Common - Transcriptional Regulator, AraC family Rru_A1456 64 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83594046 Nonpathogen - hypothetical protein Rru_A2714 1 None None None 83591720 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Rru_A0380 30 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 83591620 Common - Queuine tRNA-ribosyltransferase Rru_A0280 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 83591946 Common - adenine phosphoribosyltransferase Rru_A0607 187 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 83594471 Common - Homoserine dehydrogenase, NAD-binding Rru_A3141 35 COG4091 COG4091, Predicted homoserine dehydrogenase Amino acid transport and metabolism 83594569 Common - Plasmid stabilization system Rru_A3239 17 COG3668 ParE, Plasmid stabilization system protein General function prediction only 83593409 Common - Thiosulphate-binding protein Rru_A2074 88 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 83592842 Common - hypothetical protein Rru_A1506 99 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 83593344 Common - Glycerol kinase Rru_A2009 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 83595077 Common - translation-associated GTPase Rru_A3748 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 83592992 Common - Major facilitator superfamily MFS_1 Rru_A1657 68 None None None 83592877 Common - Methylmalonate-semialdehyde dehydrogenase Rru_A1542 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83592280 Common - Cell division protein FtsZ Rru_A0944 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 83595070 Common - 3-dehydroquinate synthase Rru_A3741 206 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 83593542 Common - hypothetical protein Rru_A2207 10 COG3070 TfoX, Regulator of competence-specific genes Transcription 83593185 Nonpathogen - hypothetical protein Rru_A1850 1 None None None 83593494 Common - Creatininase Rru_A2159 84 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 83592148 Common - hypothetical protein Rru_A0809 9 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 83593049 Common - Transcriptional Regulator, LysR family Rru_A1714 172 COG0583 LysR, Transcriptional regulator Transcription 83592344 Common - ADP-ribosyl-(dinitrogen reductase) hydrolase Rru_A1008 70 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 83592480 Common - Benzoate membrane transport protein Rru_A1144 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 83591834 Common - Squalene/phytoene synthase Rru_A0494 109 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 83593983 Common - Aminotransferase, class I and II Rru_A2651 180 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 83591461 Nonpathogen - hypothetical protein Rru_A0121 1 None None None 83591742 Common - hypothetical protein Rru_A0402 4 None None None 83594042 Common - DNA topoisomerase IV subunit B Rru_A2710 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 83592260 Common - mannose-6-phosphate isomerase Rru_A0924 48 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 83593805 Common - Ferrous iron transport protein B Rru_A2470 186 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 83592551 Common - Dihydrolipoamide dehydrogenase Rru_A1215 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 83592273 Common - Coenzyme F420 hydrogenase/dehydrogenase beta subunit-like Rru_A0937 37 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 83595103 Common - Apolipoprotein N-acyltransferase Rru_A3774 160 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 83594937 Common - hypothetical protein Rru_A3608 44 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 83592914 Common - ABC transporter component Rru_A1579 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83592926 Common - Phosphatidate cytidylyltransferase Rru_A1591 212 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 83592331 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A0995 107 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 83591631 Nonpathogen - hypothetical protein Rru_A0291 1 None None None 83592065 Common - Major facilitator superfamily MFS_1 Rru_A0726 72 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 83594184 Common - hypothetical protein Rru_A2852 123 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 83594724 Common - Transcriptional Regulator, LuxR family Rru_A3395 64 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 83592496 Common - chemotaxis sensory transducer Rru_A1160 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592141 Common - ABC transporter component Rru_A0802 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83594056 Common - Phospholipase/Carboxylesterase Rru_A2724 68 COG0400 COG0400, Predicted esterase General function prediction only 83592279 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Rru_A0943 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 83592735 Common - CheA Signal Transduction Histidine Kinases (STHK) Rru_A1399 156 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 83594833 Common - putative phenylacetate-CoA ligase Rru_A3504 108 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 83593454 Common - Molybdopterin oxidoreductase Rru_A2119 178 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 83592558 Common - primosome assembly protein PriA Rru_A1222 209 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 83591995 Common - bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase Rru_A0656 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 83594973 Common - Uracil-DNA glycosylase superfamily Rru_A3644 58 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 83593534 Nonpathogen - hypothetical protein Rru_A2199 3 None None None 83592739 Common - chemotaxis sensory transducer Rru_A1403 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593993 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A2661 176 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83593892 Common - Protein of unknown function DUF1611 Rru_A2557 35 COG3367 COG3367, Uncharacterized conserved protein Function unknown 83592908 Common - Methyladenine glycosylase Rru_A1573 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 83593152 Common - TPR repeat Rru_A1817 31 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 83591825 Common - Magnesium chelatase ATPase subunit I Rru_A0485 70 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 83592233 Common - hypothetical protein Rru_A0897 8 None None None 83591596 Common - GCN5-related N-acetyltransferase Rru_A0256 13 COG0456 RimI, Acetyltransferases General function prediction only 83592729 Nonpathogen - Nitrogenase Rru_A1393 5 None None None 83594020 Common rplC 50S ribosomal protein L3 Rru_A2688 216 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 83592891 Common - NADH dehydrogenase subunit B Rru_A1556 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 83594450 Common - hypothetical protein Rru_A3120 30 None None None 83594813 Common - Secretion protein HlyD Rru_A3484 156 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83592576 Common obgE GTPase ObgE Rru_A1240 249 COG0536 Obg, Predicted GTPase General function prediction only 83592974 Common - Na+/H+ antiporter subunit Rru_A1639 45 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 83593708 Common - Putative FecR Rru_A2373 47 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 83594050 Common - DEAD/DEAH box helicase Rru_A2718 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 83592272 Common - hypothetical protein Rru_A0936 19 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 83594678 Common - transcription activator, effector binding Rru_A3349 23 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 83592754 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Rru_A1418 219 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83592774 Common - Sigma-24 (FecI) Rru_A1438 113 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83592828 Nonpathogen - hypothetical protein Rru_A1492 3 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 83592158 Common - hypothetical protein Rru_A0821 5 None None None 83592391 Common - Protein of unknown function DUF1013 Rru_A1055 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 83594931 Common - Smr protein/MutS2-like Rru_A3602 73 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 83593585 Common - ABC transporter component Rru_A2250 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 83593958 Common - chaperone DnaJ Rru_A2626 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 83592511 Common - CsbD-like Rru_A1175 54 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 83593238 Common - inner-membrane translocator Rru_A1903 106 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 83593441 Common - Protein of unknown function DUF534 Rru_A2106 58 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 83593567 Common - Two Component Transcriptional Regulator, LuxR family Rru_A2232 184 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83593281 Common - Acetyl-CoA C-acetyltransferase Rru_A1946 174 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 83594600 Common - Hydroxyacylglutathione hydrolase Rru_A3270 204 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83592641 Common - Predicted transcriptional regulator Rru_A1305 32 COG3636 COG3636, Predicted transcriptional regulator Transcription 83593207 Common - Transcriptional Regulator, TetR family Rru_A1872 30 COG1309 AcrR, Transcriptional regulator Transcription 83594555 Common - hypothetical protein Rru_A3225 19 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 83592956 Common - tRNA-dihydrouridine synthase A Rru_A1621 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 83592414 Common - tRNA synthetase, class II (D, K and N) Rru_A1078 201 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 83594375 Common - hypothetical protein Rru_A3045 57 COG3665 COG3665, Uncharacterized conserved protein Function unknown 83593671 Common - Major facilitator superfamily MFS_1 Rru_A2336 87 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83592226 Common - Integral membrane protein TerC Rru_A0890 95 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 83594494 Common - hypothetical protein Rru_A3164 5 None None None 83593418 Common - CreA Rru_A2083 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 83591478 Common - Leucyl aminopeptidase Rru_A0138 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 83594402 Common - MscS Mechanosensitive ion channel Rru_A3072 166 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 83595042 Common - Protein of unknown function DUF159 Rru_A3713 105 COG2135 COG2135, Uncharacterized conserved protein Function unknown 83592409 Common - hypothetical protein Rru_A1073 154 COG1360 MotB, Flagellar motor protein Cell motility and secretion 83594361 Common - 2-phosphoglycolate phosphatase Rru_A3031 148 COG0546 Gph, Predicted phosphatases General function prediction only 83591394 Common - 1-deoxy-D-xylulose-5-phosphate synthase Rru_A0054 226 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 83594426 Common - Glycosyl transferase, group 1 Rru_A3096 226 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83592186 Nonpathogen - hypothetical protein Rru_A0850 1 None None None 83594465 Common - Orn/DAP/Arg decarboxylase 2 Rru_A3135 172 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 83594786 Nonpathogen - hypothetical protein Rru_A3457 1 None None None 83593464 Common fumC fumarate hydratase Rru_A2129 204 COG0114 FumC, Fumarase Energy production and conversion 83591970 Common - Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain Rru_A0631 191 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83593793 Common - Protein of unknown function DUF482 Rru_A2458 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 83592699 Common - inner-membrane translocator Rru_A1363 107 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 83593608 Common nikE nickel transporter ATP-binding protein Rru_A2273 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83592961 Common - methyltransferase Rru_A1626 35 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83593193 Common - 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK Rru_A1858 170 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 83593870 Common - Flagellar hook-associated protein 2 (FliD, filament cap protein) Rru_A2535 72 COG1345 FliD, Flagellar capping protein Cell motility and secretion 83593774 Common - Mammalian cell entry related Rru_A2439 89 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 83594699 Common - Protein of unknown function DUF6, transmembrane Rru_A3370 28 None None None 83591389 Common - Biotin/lipoyl attachment Rru_A0049 36 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 83594245 Common - Two component Transcriptional regulator, Winged helix family Rru_A2913 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83593426 Nonpathogen - hypothetical protein Rru_A2091 1 None None None 83592490 Common - Protein of unknown function DUF48 Rru_A1154 96 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83591898 Common - Alpha/beta hydrolase fold Rru_A0559 40 COG2267 PldB, Lysophospholipase Lipid metabolism 83592191 Common - Asparagine synthase Rru_A0855 31 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83593966 Common - Cobalt transport protein Rru_A2634 72 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 83591428 Common - Zinc-containing alcohol dehydrogenase superfamily Rru_A0088 131 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83593113 Nonpathogen - hypothetical protein Rru_A1778 8 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 83593788 Common - membrane anion transport protein Rru_A2453 34 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 83591362 Common - Glutathione S-transferase-like Rru_A0022 104 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83594793 Common - transcriptional regulator with PAS/PAC domain Rru_A3464 94 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 83593807 Nonpathogen - hypothetical protein Rru_A2472 6 None None None 83592177 Common - Transcriptional Regulator, AraC family Rru_A0841 95 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83592588 Common - Glutamate--ammonia ligase Rru_A1252 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 83591880 Common - MotA/TolQ/ExbB proton channel Rru_A0541 104 COG1291 MotA, Flagellar motor component Cell motility and secretion 83593037 Common - DNA polymerase III subunit delta' Rru_A1702 214 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 83592823 Common - Polysaccharide export protein Rru_A1487 97 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 83593055 Common - Carboxymuconolactone decarboxylase Rru_A1720 12 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 83591866 Nonpathogen - hypothetical protein Rru_A0527 1 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 83594250 Common - hypothetical protein Rru_A2918 6 COG4306 COG4306, Uncharacterized protein conserved in bacteria Function unknown 83591642 Common - Hydrogenase accessory protein HypB Rru_A0302 134 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 83592885 Common - Endopeptidase Clp Rru_A1550 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 83594488 Common - hypothetical protein Rru_A3158 28 COG5579 COG5579, Uncharacterized conserved protein Function unknown 83593026 Common - spermidine synthase Rru_A1691 133 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 83594636 Common - inner-membrane translocator Rru_A3306 109 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 83592534 Common - Lysine exporter protein (LYSE/YGGA) Rru_A1198 16 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83591891 Common - GCN5-related N-acetyltransferase Rru_A0552 30 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 83592509 Common - TPR repeat Rru_A1173 30 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 83593879 Common - Signal Transduction Histidine Kinase Rru_A2544 61 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 83594409 Common - 3-hydroxybutyryl-CoA dehydrogenase Rru_A3079 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 83592353 Common - Spermidine/putrescine ABC transporter ATP-binding subunit Rru_A1017 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 83592044 Common - Glutaredoxin-related protein Rru_A0705 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 83594154 Common fliR flagellar biosynthesis protein FliR Rru_A2822 129 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 83591886 Common - Flagellar hook capping protein Rru_A0547 117 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 83593400 Common - Proline racemase Rru_A2065 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 83594383 Common - homoserine kinase Rru_A3053 63 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 83594201 Common - Exopolysaccharide synthesis, ExoD Rru_A2869 49 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 83594415 Common - Pyrrolo-quinoline quinone Rru_A3085 118 COG1520 COG1520, FOG: WD40-like repeat Function unknown 83592869 Common - Cl- channel, voltage gated Rru_A1534 97 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 83592546 Common - malate dehydrogenase Rru_A1210 197 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 83594659 Common - Cytochrome c oxidase cbb3-type, subunit III Rru_A3330 77 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 83592621 Common - WD-40 repeat Rru_A1285 92 COG2319 COG2319, FOG: WD40 repeat General function prediction only 83592518 Common - MiaB-like tRNA modifying enzyme Rru_A1182 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 83594674 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Rru_A3345 187 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83594638 Common - putative transposase Rru_A3308 21 None None None 83591727 Common - Antibiotic biosynthesis monooxygenase Rru_A0387 38 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 83591949 Common - hypothetical protein Rru_A0610 15 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 83591975 Common - Protein of unknown function DUF485 Rru_A0636 49 COG3162 COG3162, Predicted membrane protein Function unknown 83591468 Common - Na+/H+ antiporter NhaA Rru_A0128 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 83594853 Common - phenylalanyl-tRNA synthetase, beta subunit Rru_A3524 232 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 83591686 Common - CRISPR-associated CT1974 family protein Rru_A0346 5 None None None 83594122 Common - Transcriptional Regulator, MarR family Rru_A2790 39 COG1846 MarR, Transcriptional regulators Transcription 83594526 Common - Plasmid stabilization system Rru_A3196 39 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 83592267 Common - Aldehyde dehydrogenase (NAD+) Rru_A0931 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83594106 Common - chemotaxis sensory transducer Rru_A2774 156 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593486 Common rpsI 30S ribosomal protein S9 Rru_A2151 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 83594070 Common - Glycosyl transferase, group 1 Rru_A2738 51 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83591486 Common - Inorganic diphosphatase Rru_A0146 184 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 83591373 Common - Cytochrome C biogenesis protein Rru_A0033 91 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 83592196 Common - RND efflux system, outer membrane lipoprotein, NodT Rru_A0860 109 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 161777623 Common flgE flagellar hook protein FlgE Rru_A2532 129 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 83591719 Common - flavodoxin FldA Rru_A0379 67 COG0716 FldA, Flavodoxins Energy production and conversion 83591756 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Rru_A0416 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83591848 Common - hypothetical protein Rru_A0509 4 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 83592898 Common - NADH dehydrogenase subunit I Rru_A1563 194 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 83593220 Common - Phosphopyruvate hydratase Rru_A1885 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 83593227 Nonpathogen - Heavy metal transport/detoxification protein Rru_A1892 2 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 83592966 Nonpathogen - hypothetical protein Rru_A1631 1 None None None 83592855 Nonpathogen - hypothetical protein Rru_A1520 1 None None None 83593580 Common - Glycogen/starch synthases, ADP-glucose type Rru_A2245 147 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 83595000 Common - bifunctional preprotein translocase subunit SecD/SecF Rru_A3671 222 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 83592694 Common tpiA triosephosphate isomerase Rru_A1358 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 83594898 Common - O-sialoglycoprotein endopeptidase Rru_A3569 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 83591775 Common - Acyl-CoA dehydrogenase Rru_A0435 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83593711 Nonpathogen - hypothetical protein Rru_A2376 4 COG3668 ParE, Plasmid stabilization system protein General function prediction only 83593437 Nonpathogen - hypothetical protein Rru_A2102 1 None None None 83594652 Nonpathogen - Cytochrome oxidase maturation protein cbb3-type Rru_A3323 2 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 83593395 Common - FAD linked oxidase Rru_A2060 196 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83595120 Nonpathogen - hypothetical protein Rru_A3791 1 None None None 83594326 Common cbiD cobalt-precorrin-6A synthase Rru_A2996 79 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 83593945 Common - hypothetical protein Rru_A2613 56 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 83591814 Common - Zinc-containing alcohol dehydrogenase superfamily Rru_A0474 123 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 83593087 Common uvrA excinuclease ABC subunit A Rru_A1752 245 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 83593613 Common - Transposase IS66 Rru_A2278 29 None None None 83593328 Nonpathogen - hypothetical protein Rru_A1993 1 None None None 83592836 Common - Signal Transduction Histidine Kinase (STHK) with CheB and CheR activity Rru_A1500 219 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 83593432 Nonpathogen - hypothetical protein Rru_A2097 3 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 83594507 Common - Glutamyl-tRNA(Gln) amidotransferase C subunit Rru_A3177 162 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 83593365 Common - hypothetical protein Rru_A2030 89 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 83594801 Common - hypothetical protein Rru_A3472 186 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 83593066 Nonpathogen - hypothetical protein Rru_A1731 3 None None None 83591548 Common - SNF2 helicase-related protein Rru_A0208 116 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 83594542 Nonpathogen - hypothetical protein Rru_A3212 8 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83591422 Common - chemotaxis sensory transducer Rru_A0082 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592151 Common - hypothetical protein Rru_A0814 8 COG5654 COG5654, Uncharacterized conserved protein Function unknown 83591603 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Rru_A0263 176 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 83591517 Common - Lytic transglycosylase, catalytic Rru_A0177 120 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 83591763 Nonpathogen - hypothetical protein Rru_A0423 1 None None None 83593518 Common - NAD(P)(+) transhydrogenase (AB-specific) Rru_A2183 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 83593739 Common - Phosphoribulokinase Rru_A2404 53 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 83592168 Common - Protein of unknown function DUF83 Rru_A0832 51 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 83593654 Common - methylcitrate synthase Rru_A2319 194 COG0372 GltA, Citrate synthase Energy production and conversion 83594574 Common - H+-transporting two-sector ATPase, B/B' subunit Rru_A3244 26 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 83592662 Nonpathogen - hypothetical protein Rru_A1326 2 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 83592130 Common - NLPA lipoprotein Rru_A0791 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 83593826 Common - Major facilitator superfamily MFS_1 Rru_A2491 17 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83594330 Common - Formate acetyltransferase Rru_A3000 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 83594864 Common - Tryptophanyl-tRNA synthetase, class Ib Rru_A3535 232 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83592753 Common - thioredoxin-disulfide reductase Rru_A1417 246 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 83593728 Common - hypothetical protein Rru_A2393 6 None None None 83592850 Common - Transposase, IS4 Rru_A1515 42 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83593167 Common - GTP cyclohydrolase I Rru_A1832 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 83595093 Common - GCN5-related N-acetyltransferase Rru_A3764 89 COG0456 RimI, Acetyltransferases General function prediction only 83592161 Common - putative transposase Rru_A0825 15 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 83593093 Nonpathogen - hypothetical protein Rru_A1758 1 None None None 83594391 Nonpathogen - hypothetical protein Rru_A3061 2 None None None 83594681 Common - Pseudouridylate synthase Rru_A3352 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 83592139 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0800 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83591545 Common - Heat shock protein DnaJ-like Rru_A0205 96 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 83592648 Common - AMP-dependent synthetase and ligase Rru_A1312 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83593628 Nonpathogen - hypothetical protein Rru_A2293 1 COG2406 COG2406, Protein distantly related to bacterial ferritins General function prediction only 83592308 Common - Prephenate dehydrogenase Rru_A0972 57 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 83591709 Common - ATPase associated with various cellular activities, AAA_3 Rru_A0369 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 83594428 Nonpathogen - hypothetical protein Rru_A3098 1 None None None 83594712 Common - Cobalamin (vitamin B12) biosynthesis CbiG protein Rru_A3383 16 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 83593028 Common - Orn/DAP/Arg decarboxylase 2 Rru_A1693 213 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 83592809 Common - hypothetical protein Rru_A1473 31 None None None 83594222 Common - hypothetical protein Rru_A2890 28 None None None 83591971 Common - chemotaxis sensory transducer Rru_A0632 170 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592584 Nonpathogen - hypothetical protein Rru_A1248 1 None None None 83594749 Common - Pyridoxamine 5'-phosphate oxidase-related, FMN-binding Rru_A3420 39 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 83592844 Common - FAD dependent oxidoreductase Rru_A1508 152 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 83592217 Common - ABC transporter component Rru_A0881 246 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83591593 Common - GDP-mannose 4,6-dehydratase Rru_A0253 211 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 83593676 Nonpathogen - hypothetical protein Rru_A2341 1 None None None 83593138 Common - Undecaprenol kinase Rru_A1803 201 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 83591859 Nonpathogen - hypothetical protein Rru_A0520 4 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 83594587 Common - Phospholipid/glycerol acyltransferase Rru_A3257 196 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 83594272 Common - Glycine cleavage T protein (aminomethyl transferase) Rru_A2940 75 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 83593772 Common - cellulase-like protein Rru_A2437 30 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 83594501 Nonpathogen - hypothetical protein Rru_A3171 1 None None None 83594081 Common - Protein of unknown function DUF214 Rru_A2749 150 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 83594690 Nonpathogen - hypothetical protein Rru_A3361 2 COG2836 COG2836, Uncharacterized conserved protein Function unknown 83591346 Common - Plasmid maintenance system antidote protein Rru_A0006 24 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 83594595 Common - Chorismate mutase Rru_A3265 58 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 83591388 Common - Lysine exporter protein (LYSE/YGGA) Rru_A0048 108 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83594086 Common - Cold-shock DNA-binding domain protein Rru_A2754 139 COG1278 CspC, Cold shock proteins Transcription 83594142 Common - Saccharopine dehydrogenase Rru_A2810 30 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 83594243 Nonpathogen - ABC-type uncharacterized transport system auxiliary component-like Rru_A2911 2 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 83594929 Common hslU ATP-dependent protease ATP-binding subunit Rru_A3600 213 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 83593335 Nonpathogen - hypothetical protein Rru_A2000 6 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 83592825 Common - hypothetical protein Rru_A1489 23 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 83591877 Common - hypothetical protein Rru_A0538 6 None None None 83594557 Common - conserved hypothetical protein, potential methyltransferase Rru_A3227 5 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83591359 Common - Glutamate synthase (ferredoxin) Rru_A0019 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 83593475 Common - Transcriptional Regulator, XRE family Rru_A2140 22 COG2932 COG2932, Predicted transcriptional regulator Transcription 83591582 Common - Type III restriction enzyme, res subunit Rru_A0242 20 None None None 83593385 Common - Secretion protein HlyD Rru_A2050 166 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83593837 Common - Protein of unknown function DUF454 Rru_A2502 51 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 83591446 Nonpathogen - TPR repeat, Tetratricopeptide TPR_4 Rru_A0106 1 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 83591680 Common - CRISPR-associated helicase Cas3, core Rru_A0340 69 COG1203 COG1203, Predicted helicases General function prediction only 83592875 Common - Transcriptional Regulator, LysR family Rru_A1540 45 COG0583 LysR, Transcriptional regulator Transcription 83592687 Common - hypothetical protein Rru_A1351 22 None None None 83593053 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Rru_A1718 132 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 83593329 Common - Transcriptional Regulator, MerR family Rru_A1994 101 COG0789 SoxR, Predicted transcriptional regulators Transcription 83594062 Nonpathogen - hypothetical protein Rru_A2730 3 None None None 83591992 Common - hypothetical protein Rru_A0653 207 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 83594348 Common - hypothetical protein Rru_A3018 19 None None None 83592962 Common - hypothetical protein Rru_A1627 6 COG3784 COG3784, Uncharacterized protein conserved in bacteria Function unknown 83593218 Common - Magnesium and cobalt transport protein CorA Rru_A1883 152 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 83594705 Common - Glycosyl transferase, group 1 Rru_A3376 185 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83591536 Nonpathogen - hypothetical protein Rru_A0196 1 None None None 83592566 Common - NUDIX hydrolase Rru_A1230 115 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 83593240 Common - ABC transporter component Rru_A1905 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 83594908 Common - heat shock protein HtpX Rru_A3579 190 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 83595005 Common - TRAP dicarboxylate transporter, DctM subunit Rru_A3676 124 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 83594981 Common - hypothetical protein Rru_A3652 28 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83592008 Common - Phosphoglycerate/bisphosphoglycerate mutase Rru_A0669 57 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 83592432 Common - hypothetical protein Rru_A1096 103 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 83593270 Common - Transcriptional Regulator, LuxR family Rru_A1935 37 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83593660 Common - MCP methyltransferase, CheR-type Rru_A2325 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 83594148 Common - Transcriptional Regulator, TetR family Rru_A2816 103 COG1309 AcrR, Transcriptional regulator Transcription 83591533 Common - Beta-ketoacyl synthase Rru_A0193 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83594990 Common - Major facilitator superfamily MFS_1 Rru_A3661 79 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 83594773 Common - S-adenosyl-L-homocysteine hydrolase Rru_A3444 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 83592228 Common - stress protein Rru_A0892 27 COG4110 COG4110, Uncharacterized protein involved in stress response General function prediction only 83592001 Common - Translation initiation factor IF-1 Rru_A0662 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 83594009 Common - Ribosomal protein L24 Rru_A2677 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 83591696 Common - isocitrate dehydrogenase Rru_A0356 62 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 83592635 Common - FAD linked oxidase-like Rru_A1299 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83593747 Nonpathogen - OmpA/MotB Rru_A2412 2 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83593572 Common - TRAP dicarboxylate transporter, DctM subunit Rru_A2237 129 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 83594784 Common - Binding-protein-dependent transport systems inner membrane component Rru_A3455 59 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 83594957 Common - ParB-like partition protein Rru_A3628 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 83591937 Common - phosphate ABC transporter, periplasmic binding protein Rru_A0598 125 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 83592602 Common - Photosystem I assembly BtpA Rru_A1266 38 COG0434 SgcQ, Predicted TIM-barrel enzyme General function prediction only 83594751 Common - Two component Transcriptional regulator, Winged helix family Rru_A3422 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83592153 Common - hypothetical protein Rru_A0816 27 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 83594170 Common - hypothetical protein Rru_A2838 17 COG3334 COG3334, Uncharacterized conserved protein Function unknown 83593082 Common - hypothetical protein Rru_A1747 10 None None None 83595019 Common - glutathione synthetase Rru_A3690 133 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 83591797 Common - Protein of unknown function DUF891 Rru_A0457 41 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 83593062 Common - Protein of unknown function DUF339 Rru_A1727 37 COG2938 COG2938, Uncharacterized conserved protein Function unknown 83593411 Common - chemotaxis sensory transducer Rru_A2076 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594988 Nonpathogen - hypothetical protein Rru_A3659 4 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 83595029 Common - Secretion protein HlyD Rru_A3700 169 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83592942 Common - 4-alpha-glucanotransferase Rru_A1607 118 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 83594896 Common - Uroporphyrinogen III synthase HEM4 Rru_A3567 35 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 83593841 Common - Enoyl-CoA hydratase/isomerase Rru_A2506 173 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83592244 Common - microcompartments protein Rru_A0908 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 83592289 Common - Phospho-N-acetylmuramoyl-pentapeptide transferase Rru_A0953 219 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 83594934 Common - Iron-sulfur cluster binding protein Rru_A3605 96 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 83594141 Common - Iron permease FTR1 Rru_A2809 94 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 83592442 Common - adenylosuccinate synthetase Rru_A1106 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 83594993 Common - ABC transporter component Rru_A3664 248 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83593520 Common - indolepyruvate ferredoxin oxidoreductase Rru_A2185 93 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 83591864 Common - Two component Transcriptional regulator, Winged helix family Rru_A0525 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83591823 Nonpathogen - hypothetical protein Rru_A0483 1 None None None 83594032 Common nusG transcription antitermination protein NusG Rru_A2700 216 COG0250 NusG, Transcription antiterminator Transcription 83594513 Common - diheme cytochrome c Rru_A3183 15 None None None 83593071 Nonpathogen - hypothetical protein Rru_A1736 1 None None None 83593888 Common - Methylase involved in ubiquinone/menaquinone biosynthesis-like Rru_A2553 134 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83593078 Common - Coenzyme A biosynthesis protein Rru_A1743 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 83593784 Nonpathogen - hypothetical protein Rru_A2449 2 None None None 83591665 Common - Molybdenum cofactor biosynthesis protein Rru_A0325 193 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 83594036 Nonpathogen - hypothetical protein Rru_A2704 1 None None None 83594289 Nonpathogen - hypothetical protein Rru_A2957 1 None None None 83592431 Common - OmpA/MotB Rru_A1095 154 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83594015 Common rplV 50S ribosomal protein L22 Rru_A2683 216 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 83594217 Common - Carbamoyl-phosphate synthase, small subunit Rru_A2885 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 83591968 Common - Geranylgeranyl reductase Rru_A0629 53 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 83593007 Nonpathogen - hypothetical protein Rru_A1672 1 None None None 83591947 Common - TRAP transporter solute receptor, TAXI family Rru_A0608 88 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 83594562 Common - Thermostable carboxypeptidase 1 Rru_A3232 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 83594946 Common - Ferrochelatase Rru_A3617 176 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 83593543 Common - hypothetical protein Rru_A2208 31 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 83593913 Nonpathogen - hypothetical protein Rru_A2581 1 None None None 83591839 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0499 165 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 83591589 Common - ABC transporter component Rru_A0249 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 83592486 Nonpathogen - hypothetical protein Rru_A1150 1 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 83592773 Common - C4-dicarboxylate transporter DctA Rru_A1437 160 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 83591818 Common - Radical SAM Rru_A0478 47 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 83594532 Common - DNA topoisomerase I Rru_A3202 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 83593399 Common - FAD dependent oxidoreductase Rru_A2064 106 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 83592677 Common - Dak phosphatase Rru_A1341 70 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 83594918 Common - Mg chelatase-related protein Rru_A3589 187 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 83594975 Common - Protein tyrosine phosphatase Rru_A3646 137 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 83591874 Common - Protein of unknown function DUF6, transmembrane Rru_A0535 86 None None None 83592476 Common - elongation factor G Rru_A1140 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 83591927 Common - Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like Rru_A0588 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 83593846 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A2511 184 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83595010 Common - YceI Rru_A3681 120 COG2353 COG2353, Uncharacterized conserved protein Function unknown 83592591 Common - Transcriptional Regulator, GntR family Rru_A1255 25 COG1802 GntR, Transcriptional regulators Transcription 83594920 Nonpathogen - hypothetical protein Rru_A3591 3 None None None 83594823 Common - Putative diguanylate phosphodiesterase (EAL domain) with Response Regulator Receiver modulation Rru_A3494 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83593649 Nonpathogen - hypothetical protein Rru_A2314 1 None None None 83592046 Common - BolA-like protein Rru_A0707 83 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 83594815 Nonpathogen - hypothetical protein Rru_A3486 8 COG2119 COG2119, Predicted membrane protein Function unknown 83593372 Common - hypothetical protein Rru_A2037 33 None None None 83594280 Nonpathogen - hypothetical protein Rru_A2948 5 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 83593350 Common - chaperone DnaJ Rru_A2015 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 83591629 Common - NUDIX hydrolase Rru_A0289 100 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 83592315 Common - extracellular solute-binding protein, family 5 Rru_A0979 183 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 83593822 Common - BsuBIPstI restriction endonuclease-like Rru_A2487 16 None None None 83592849 Nonpathogen - hypothetical protein Rru_A1513 1 COG2361 COG2361, Uncharacterized conserved protein Function unknown 83593098 Common - SecF protein Rru_A1763 206 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 83593549 Common - Transcriptional Regulator, LysR family Rru_A2214 147 COG0583 LysR, Transcriptional regulator Transcription 83591982 Common - Protein of unknown function DUF152 Rru_A0643 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 83595118 Common - Protein of unknown function DUF1058 Rru_A3789 43 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 83593377 Common - Transcriptional Regulator, XRE family with Cupin sensor domain Rru_A2042 112 COG1396 HipB, Predicted transcriptional regulators Transcription 83594695 Common cobN cobaltochelatase Rru_A3366 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 83592026 Common nadE NAD synthetase Rru_A0687 209 COG0171 NadE, NAD synthase Coenzyme metabolism 83594405 Common - permease YjgP/YjgQ Rru_A3075 82 COG0795 COG0795, Predicted permeases General function prediction only 83591850 Common - DEAD/DEAH box helicase Rru_A0511 114 COG1204 COG1204, Superfamily II helicase General function prediction only 83591571 Nonpathogen - hypothetical protein Rru_A0231 1 None None None 83593127 Common - ABC transporter component Rru_A1792 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83593164 Common - Transcriptional Regulator, MucR family Rru_A1829 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 83592932 Common - UDP-N-acetylglucosamine acyltransferase Rru_A1597 143 COG1043 LpxA, Acyl- acyl carrier protein 83594079 Common - gluconate 5-dehydrogenase Rru_A2747 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83594161 Common - hypothetical protein Rru_A2829 15 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 83591755 Common - Malonyl CoA-acyl carrier protein transacylase Rru_A0415 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 83593798 Common - N-formylglutamate amidohydrolase Rru_A2463 42 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 83592255 Common - Two Component Transcriptional Regulator, AraC family Rru_A0919 220 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 83594368 Common - hypothetical protein Rru_A3038 15 None None None 83594446 Nonpathogen - hypothetical protein Rru_A3116 7 None None None 83593179 Common - RDD Rru_A1844 15 COG1714 COG1714, Predicted membrane protein/domain Function unknown 83591558 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha Rru_A0218 179 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 83591411 Nonpathogen - hypothetical protein Rru_A0071 1 None None None 83593159 Common - riboflavin synthase subunit alpha Rru_A1824 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 83593853 Common - Multiple antibiotic resistance (MarC)-related proteins Rru_A2518 152 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 83594162 Common fliP flagellar biosynthesis protein FliP Rru_A2830 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 83593756 Common - N-acetyl-gamma-glutamyl-phosphate reductase Rru_A2421 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 83594237 Common - Protein of unknown function DUF6, transmembrane Rru_A2905 32 None None None 83595044 Common - Lipopolysaccharide biosynthesis Rru_A3715 27 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 83591959 Common chlL protochlorophyllide reductase iron-sulfur ATP-binding protein Rru_A0620 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 83592376 Common - Glu/Leu/Phe/Val dehydrogenase Rru_A1040 88 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 83592421 Common - Metallophosphoesterase Rru_A1085 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 83594888 Nonpathogen - Heat shock protein DnaJ-like Rru_A3559 2 None None None 83593229 Common - heavy metal translocating P-type ATPase Rru_A1894 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 83593231 Common - Anthranilate phosphoribosyl transferase Rru_A1896 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 83594792 Common - Transcriptional Regulator, AsnC family Rru_A3463 20 COG1522 Lrp, Transcriptional regulators Transcription 83593637 Common - Periplasmic binding protein/LacI transcriptional regulator Rru_A2302 73 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83594013 Common rplP 50S ribosomal protein L16 Rru_A2681 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 83592821 Nonpathogen - Parallel beta-helix repeat Rru_A1485 2 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 83592059 Common - Transcriptional Regulator, MarR family Rru_A0720 23 COG1846 MarR, Transcriptional regulators Transcription 83592628 Common - Protein of unknown function DUF214 Rru_A1292 27 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 83591421 Common - chemotaxis sensory transducer Rru_A0081 142 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593640 Common - Haloacid dehalogenase-like hydrolase Rru_A2305 27 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 83592072 Common - Peptidase M24A, methionine aminopeptidase, subfamily 1 Rru_A0733 246 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 83594074 Common - O-linked N-acetylglucosamine transferase SPINDLY family-like Rru_A2742 6 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 83594872 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Rru_A3543 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 83591989 Common - Cytidine/deoxycytidylate deaminase, zinc-binding region Rru_A0650 202 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 83593590 Common upp uracil phosphoribosyltransferase Rru_A2255 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 83593116 Common - HesB/YadR/YfhF Rru_A1781 161 COG0316 IscA, Uncharacterized conserved protein Function unknown 83592200 Common - ABC transporter, transmembrane region Rru_A0864 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83592870 Common - Plasmid maintenance system antidote protein Rru_A1535 72 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 83594210 Nonpathogen - hypothetical protein Rru_A2878 4 None None None 83592527 Common - 3-isopropylmalate dehydrogenase Rru_A1191 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 83591687 Common - Protein of unknown function DUF48 Rru_A0347 50 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83591524 Nonpathogen - Protein of unknown function DUF324 Rru_A0184 5 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 83594844 Common - Transcriptional Regulator, LytR/AlgR family Rru_A3515 50 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 83593897 Common - CheW protein Rru_A2562 113 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 83593931 Common - Tat-translocated enzyme Rru_A2599 42 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 83593588 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Rru_A2253 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 83595083 Nonpathogen - hypothetical protein Rru_A3754 1 None None None 83594644 Common - Uncharacterized phage-encoded protein-like Rru_A3314 24 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 83594485 Common - hypothetical protein Rru_A3155 12 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 83591677 Common - Predicted transcriptional regulator Rru_A0337 134 COG1733 COG1733, Predicted transcriptional regulators Transcription 83592655 Common - Triphosphoribosyl-dephospho-CoA synthase Rru_A1319 48 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 83591578 Nonpathogen - hypothetical protein Rru_A0238 1 None None None 83593965 Common - ABC transporter component Rru_A2633 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 83592126 Common - cysteine synthase Rru_A0787 215 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 83593380 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2045 219 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 83594058 Common - Response regulator receiver domain protein (CheY) Rru_A2726 214 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 83593595 Nonpathogen - hypothetical protein Rru_A2260 1 None None None 83592536 Common - Citrate lyase Rru_A1200 108 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 83591700 Common mtnA methylthioribose-1-phosphate isomerase Rru_A0360 130 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 83592888 Common - Histone-like DNA-binding protein Rru_A1553 209 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 83593553 Common - short chain dehydrogenase Rru_A2218 228 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83592881 Common - FAD dependent oxidoreductase Rru_A1546 144 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 83593938 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Rru_A2606 204 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 83594797 Common - Transcriptional Regulator, AsnC family Rru_A3468 89 COG1522 Lrp, Transcriptional regulators Transcription 83591913 Common - Carboxylyase-related protein Rru_A0574 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 83594306 Nonpathogen - Antenna complex, alpha/beta subunit Rru_A2976 7 None None None 83593904 Common - FeS assembly ATPase SufC Rru_A2572 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 83592574 Common - Gamma-glutamyl phosphate reductase GPR Rru_A1238 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 83591990 Common - Glutamine amidotransferase class-I Rru_A0651 110 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 83591509 Common - Protein of unknown function DUF48 Rru_A0169 45 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83594731 Common - sulfate ABC transporter, permease protein CysW Rru_A3402 222 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 83593337 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Rru_A2002 215 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 83592520 Common - Signal recognition particle protein Rru_A1184 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 83593222 Common - CTP synthetase Rru_A1887 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 83593462 Common - Serine 3-dehydrogenase Rru_A2127 233 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 83594520 Common - Aspartate carbamoyltransferase Rru_A3190 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 83594531 Common - ABC transporter component Rru_A3201 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 83593663 Nonpathogen - hypothetical protein Rru_A2328 1 None None None 83594308 Common - Chlorophyllide reductase subunit Z Rru_A2978 32 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83594490 Common - Protein of unknown function DUF6, transmembrane Rru_A3160 107 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83592270 Common - hypothetical protein Rru_A0934 10 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 83594738 Nonpathogen - hypothetical protein Rru_A3409 1 None None None 83593890 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A2555 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83592202 Common - Major facilitator superfamily MFS_1 Rru_A0866 97 None None None 83592235 Common - hypothetical protein Rru_A0899 24 None None None 83593834 Common - ABC-2 transporter component Rru_A2499 124 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 83594496 Common - extracellular solute-binding protein, family 5 Rru_A3166 177 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 83593283 Common - Acyl-CoA dehydrogenase Rru_A1948 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83593024 Nonpathogen - hypothetical protein Rru_A1689 2 None None None 83593236 Common - chemotaxis sensory transducer Rru_A1901 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594602 Common - Protein of unknown function DUF6, transmembrane Rru_A3272 111 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83592703 Common - Sugar isomerase (SIS) Rru_A1367 46 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 83591492 Nonpathogen - hypothetical protein Rru_A0152 2 None None None 83592650 Nonpathogen - hypothetical protein Rru_A1314 6 None None None 83593956 Common - Short-chain dehydrogenase/reductase SDR Rru_A2624 211 COG0623 FabI, Enoyl- acyl-carrier-protein 83594631 Common - hypothetical protein Rru_A3301 22 COG5368 COG5368, Uncharacterized protein conserved in bacteria Function unknown 83592529 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis Rru_A1193 14 COG1433 COG1433, Uncharacterized conserved protein Function unknown 83594400 Common - Transcriptional Regulator, AsnC family Rru_A3070 154 COG1522 Lrp, Transcriptional regulators Transcription 83594697 Common - Transcriptional Regulator, LysR family Rru_A3368 173 COG0583 LysR, Transcriptional regulator Transcription 83593118 Nonpathogen - hypothetical protein Rru_A1783 3 None None None 83594478 Common - Protein of unknown function DUF323 Rru_A3148 32 COG1262 COG1262, Uncharacterized conserved protein Function unknown 83591734 Common - Amino-acid N-acetyltransferase Rru_A0394 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 83593205 Common - CinA-like Rru_A1870 191 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 83593963 Common - hypothetical protein Rru_A2631 84 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 83593718 Common - ABC transporter component Rru_A2383 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 83593305 Common - PTS fructose IIC component Rru_A1970 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 83592900 Common - NADH-ubiquinone oxidoreductase, chain 4L Rru_A1565 165 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 83592412 Common - Inositol monophosphatase Rru_A1076 214 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 83594363 Common - hypothetical protein Rru_A3033 14 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 83592241 Common - microcompartments protein Rru_A0905 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 83591500 Common - hypothetical protein Rru_A0160 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 83591676 Common - hypothetical protein Rru_A0336 33 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83593972 Nonpathogen - hypothetical protein Rru_A2640 2 None None None 83591987 Common - hypothetical protein Rru_A0648 17 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 83595033 Common - Periplasmic solute binding protein Rru_A3704 172 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 83592358 Nonpathogen - hypothetical protein Rru_A1022 1 None None None 83593569 Common - Response regulator receiver domain protein (CheY) Rru_A2234 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83592188 Common - hypothetical protein Rru_A0852 12 None None None 83594457 Common - Pyridoxamine 5'-phosphate oxidase-related, FMN-binding Rru_A3127 49 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 83591543 Nonpathogen - hypothetical protein Rru_A0203 1 None None None 83592788 Common - GCN5-related N-acetyltransferase Rru_A1452 18 COG0456 RimI, Acetyltransferases General function prediction only 83592092 Common - Chaperone clpB Rru_A0753 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 83595058 Common - Creatininase Rru_A3729 85 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 83594109 Common - Protein of unknown function DUF6, transmembrane Rru_A2777 137 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83591418 Nonpathogen - hypothetical protein Rru_A0078 1 None None None 83592351 Common - Binding-protein-dependent transport systems inner membrane component Rru_A1015 188 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 83594356 Common - HPr kinase Rru_A3026 20 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 83593619 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis Rru_A2284 32 None None None 83593496 Common - polyphosphate kinase Rru_A2161 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 83594011 Common - Ribosomal protein S17 Rru_A2679 231 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 83594048 Common - Acyltransferase 3 Rru_A2716 16 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 83594769 Nonpathogen - hypothetical protein Rru_A3440 1 None None None 83592341 Common - Glycosyl transferase, family 2 Rru_A1005 212 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83592862 Common - putative ABC transporter ATP-binding protein Rru_A1527 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 83595075 Common - Ribosomal protein L25 Rru_A3746 171 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 83592737 Common - chemotaxis sensory transducer Rru_A1401 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594430 Common - hypothetical protein Rru_A3100 16 None None None 83594740 Common - Transcriptional Regulator, XRE family Rru_A3411 25 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 83591882 Nonpathogen fliH flagellar assembly protein H Rru_A0543 9 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 83595105 Common - S-adenosylmethionine synthetase Rru_A3776 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 83592404 Common - Aminotransferase, class V Rru_A1068 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 83592326 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Rru_A0990 166 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83594114 Common - Transcriptional Regulator, LysR family Rru_A2782 189 COG0583 LysR, Transcriptional regulator Transcription 83593108 Common - Twin-arginine translocation protein TatA/E Rru_A1773 20 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 83593009 Common - bifunctional enzyme, 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, 4-diphosphocytidyl-2C- methyl-D-erythritol synthase Rru_A1674 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 83591744 Common - amidophosphoribosyltransferase Rru_A0404 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 83593183 Common - DNA topoisomerase IV subunit A Rru_A1848 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 83591622 Common - Protein of unknown function DUF204 Rru_A0282 56 COG1971 COG1971, Predicted membrane protein Function unknown 83592516 Common - Major facilitator superfamily MFS_1 Rru_A1180 45 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83592146 Common - Conjugal transfer protein TrbC Rru_A0807 31 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 83592216 Common - TonB-dependent receptor Rru_A0880 122 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 83594115 Common - Predicted periplasmic ligand-binding sensor protein Rru_A2783 22 COG3416 COG3416, Uncharacterized protein conserved in bacteria Function unknown 83593187 Common - Ribonuclease III Rru_A1852 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 83591997 Common - chromosome replication initiation inhibitor protein Rru_A0658 98 COG0583 LysR, Transcriptional regulator Transcription 83592762 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A1426 152 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 83592277 Common - competence lipoprotein ComL, putative Rru_A0941 125 COG4105 ComL, DNA uptake lipoprotein General function prediction only 83593129 Common - Transcriptional Regulator, TetR family Rru_A1794 55 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 83592063 Common - Protein of unknown function DUF1365 Rru_A0724 61 COG3496 COG3496, Uncharacterized conserved protein Function unknown 83593985 Common - hypothetical protein Rru_A2653 2 None None None 83593358 Common - chemotaxis sensory transducer Rru_A2023 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83591466 Common - ABC transporter component Rru_A0126 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83591457 Common - ABC transporter component Rru_A0117 220 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 83592928 Common - Peptidase M50, putative membrane-associated zinc metallopeptidase Rru_A1593 209 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 83592144 Common - conjugal transfer protein Rru_A0805 33 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 83593272 Nonpathogen - hypothetical protein Rru_A1937 9 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 83594182 Common - hypothetical protein Rru_A2850 25 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 83591922 Common - Glycosyl transferase, group 1 Rru_A0583 157 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83591832 Common - hypothetical protein Rru_A0492 33 COG1865 COG1865, Uncharacterized conserved protein Function unknown 83593506 Common - Extracellular ligand-binding receptor Rru_A2171 140 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83592498 Common - Nickel-dependent hydrogenase, large subunit Rru_A1162 105 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 83592756 Common - NADH dehydrogenase (quinone) Rru_A1420 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 83593000 Common rpmF 50S ribosomal protein L32 Rru_A1665 121 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 83593452 Common - UTP--glucose-1-phosphate uridylyltransferase Rru_A2117 229 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 83593539 Common - Protein of unknown function DUF59 Rru_A2204 237 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83594688 Common - cobyrinic acid a,c-diamide synthase Rru_A3359 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 83594108 Common - ChaC-like protein Rru_A2776 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 83594044 Common - Transcriptional Regulator, TetR family Rru_A2712 54 COG1309 AcrR, Transcriptional regulator Transcription 83594655 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A3326 85 COG0348 NapH, Polyferredoxin Energy production and conversion 83594398 Common - Plasmid maintenance system antidote protein Rru_A3068 80 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 83592349 Common - ABC transporter component Rru_A1013 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 83593758 Common - Aminotransferase, class I and II Rru_A2423 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83594771 Common - Transposase IS116/IS110/IS902 Rru_A3442 62 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 83595087 Nonpathogen - hypothetical protein Rru_A3758 1 None None None 83593288 Nonpathogen - hypothetical protein Rru_A1953 1 None None None 83593940 Nonpathogen - hypothetical protein Rru_A2608 1 None None None 83592970 Common - putative monovalent cation/H+ antiporter subunit D Rru_A1635 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 83592664 Common - Biotin/lipoyl attachment Rru_A1328 179 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 83591471 Common - Response regulator receiver (CheY) and unknown domain protein Rru_A0131 28 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 83592906 Common - metallo-beta-lactamase Rru_A1571 154 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 83594077 Common - hypothetical protein Rru_A2745 7 None None None 83594867 Common - Virulence factor MVIN-like Rru_A3538 187 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 83595046 Common - Glycosyl transferase WecB/TagA/CpsF Rru_A3717 75 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 83593706 Common - hydroxyacylglutathione hydrolase Rru_A2371 31 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 83593141 Common - MotA/TolQ/ExbB proton channel Rru_A1806 82 COG1291 MotA, Flagellar motor component Cell motility and secretion 83592393 Common - 3-hydroxybutyrate dehydrogenase Rru_A1057 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83593811 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2476 220 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 83594441 Common - Metallophosphoesterase Rru_A3111 85 None None None 83592746 Common - 4Fe-4S ferredoxin Rru_A1410 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83593995 Common - Ribosomal protein L17 Rru_A2663 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 83592857 Common - Beta-lactamase-like Rru_A1522 218 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83594610 Common - hypothetical protein Rru_A3280 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 83595069 Common - Shikimate kinase Rru_A3740 195 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 83592911 Common - prolyl-tRNA synthetase Rru_A1576 246 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83594291 Common - hypothetical protein Rru_A2961 6 None None None 83593653 Common - 2-methylcitrate dehydratase Rru_A2318 61 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 83594650 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase Rru_A3321 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 83591889 Common - TPR repeat Rru_A0550 60 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 83593264 Common - phosphoadenosine phosphosulfate reductase Rru_A1929 158 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 83593085 Common - inner-membrane translocator Rru_A1750 141 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 83592954 Nonpathogen - hypothetical protein Rru_A1619 1 None None None 83591416 Common - Protein of unknown function DUF1332 Rru_A0076 38 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 83593300 Nonpathogen - hypothetical protein Rru_A1965 1 None None None 83594760 Common - Folylpolyglutamate synthetase Rru_A3431 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 83591906 Common - Peptidase U62, modulator of DNA gyrase Rru_A0567 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 83591657 Common - Respiratory-chain NADH dehydrogenase, subunit 1 Rru_A0317 189 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 83593582 Nonpathogen - hypothetical protein Rru_A2247 1 None None None 83593322 Common - peptidase M42 Rru_A1987 74 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 83592042 Common - Molybdate ABC transporter, permease protein Rru_A0703 226 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 83593296 Common - Transcriptional Regulator, TetR family Rru_A1961 63 COG1309 AcrR, Transcriptional regulator Transcription 83594424 Common - O-antigen polymerase Rru_A3094 23 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 83594803 Common - Bacterioferritin Rru_A3474 103 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 83592771 Common - Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family Rru_A1435 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83591812 Nonpathogen - hypothetical protein Rru_A0472 4 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 83594324 Common - hypothetical protein Rru_A2994 8 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83593950 Common - Polyprenyl synthetase Rru_A2618 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 83594179 Common - Transcriptional regulators, TraR/DksA family Rru_A2847 158 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 83592133 Common - Nitrogenase Rru_A0794 61 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83593434 Common - surface antigen Rru_A2099 143 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 83593821 Common - Glucokinase Rru_A2486 88 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 83594544 Common - O-succinylhomoserine sulfhydrylase Rru_A3214 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 83593516 Common - NAD(P) transhydrogenase, beta subunit Rru_A2181 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 83592411 Common - hypothetical protein Rru_A1075 5 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83591944 Common - hypothetical protein Rru_A0605 117 COG2855 COG2855, Predicted membrane protein Function unknown 83592093 Common - hypothetical protein Rru_A0754 7 None None None 83594509 Common - GCN5-related N-acetyltransferase Rru_A3179 53 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 83595126 Common - 2-polyprenylphenol 6-hydroxylase Rru_A3797 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 83592852 Nonpathogen - transposase of ISBst12-like element Rru_A1517 12 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 83592163 Common - hypothetical protein Rru_A0827 14 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83594247 Nonpathogen - hypothetical protein Rru_A2915 1 None None None 83594862 Common - hypothetical protein Rru_A3533 27 None None None 83593872 Common - RNA polymerase sigma factor Rru_A2537 154 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83593611 Common - nickel transporter permease NikB Rru_A2276 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83592984 Common - hypothetical protein Rru_A1649 4 None None None 83594664 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Rru_A3335 162 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 83593828 Common - Glycosyl transferase, group 1 Rru_A2493 211 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83593726 Common - hypothetical protein Rru_A2391 4 None None None 83593673 Common - Transcriptional Regulator, AraC family Rru_A2338 60 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83593095 Common - Superoxide dismutase Rru_A1760 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 83592155 Common - hypothetical protein Rru_A0818 13 None None None 83592994 Common - Putative diguanylate phosphodiesterase (EAL domain) Rru_A1659 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83594572 Common - Transcriptional Regulator, XRE family Rru_A3242 42 COG1396 HipB, Predicted transcriptional regulators Transcription 83594683 Common - Protein of unknown function DUF45 Rru_A3354 117 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 83593809 Common - extracellular solute-binding protein, family 5 Rru_A2474 104 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 83594388 Common - putative suppressor for copper-sensitivity B precursor Rru_A3058 156 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 83591375 Common - Cytochrome c-type biogenesis protein CcmF Rru_A0035 153 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 83594858 Common - inner-membrane translocator Rru_A3529 115 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 83591426 Common - Protein of unknown function DUF188 Rru_A0086 93 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 83591365 Nonpathogen - hypothetical protein Rru_A0025 1 None None None 83591703 Common - Cytochrome b/b6-like Rru_A0363 147 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 83592057 Common - chemotaxis sensory transducer Rru_A0718 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594598 Nonpathogen - hypothetical protein Rru_A3268 1 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 83592193 Common - Sulfotransferase Rru_A0857 14 None None None 83592105 Common - adenosine deaminase Rru_A0766 98 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 83593213 Common - dihydrolipoamide dehydrogenase Rru_A1878 240 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 83592224 Common - Transcriptional Regulator, TetR family Rru_A0888 85 COG1309 AcrR, Transcriptional regulator Transcription 83594252 Common - hypothetical protein Rru_A2920 33 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 83592586 Common - Beta-lactamase Rru_A1250 63 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 83591445 Common - Penicillin-binding protein 1C Rru_A0105 199 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 83593291 Common - Haloacid dehalogenase-like hydrolase Rru_A1956 9 COG0546 Gph, Predicted phosphatases General function prediction only 83591896 Common - Methenyltetrahydrofolate cyclohydrolase Rru_A0557 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 83594131 Nonpathogen - hypothetical protein Rru_A2799 4 None None None 83594851 Common rplT 50S ribosomal protein L20 Rru_A3522 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 83594270 Common - Glycosyl transferase, group 1 Rru_A2938 219 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83592198 Common - Transcriptional Regulator, AraC family Rru_A0862 70 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83592383 Common - 6-phosphofructokinase Rru_A1047 157 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 83594661 Common - Cytochrome c oxidase cbb3-type, subunit I Rru_A3332 156 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 83592452 Common - Transcriptional Regulator, TetR family Rru_A1116 33 COG1309 AcrR, Transcriptional regulator Transcription 83593121 Common - Dihydroxy-acid dehydratase Rru_A1786 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 83594301 Common - Drug resistance transporter Bcr/CflA subfamily Rru_A2971 220 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83591841 Nonpathogen - hypothetical protein Rru_A0502 2 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 83594669 Common - GTPase EngB Rru_A3340 189 COG0218 COG0218, Predicted GTPase General function prediction only 83594726 Nonpathogen - hypothetical protein Rru_A3397 1 None None None 83593703 Nonpathogen - transcriptional regulator with PAS/PAC domain Rru_A2368 2 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 83592817 Common - hypothetical protein Rru_A1481 2 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 83594944 Common - hypothetical protein Rru_A3615 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 83594528 Common - HicA protein Rru_A3198 21 None None None 83591364 Common - peptidase Rru_A0024 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 83591564 Common - Protein of unknown function DUF160 Rru_A0224 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 83593555 Common uvrC excinuclease ABC subunit C Rru_A2220 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 83593348 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2013 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83592778 Common - lipoprotein, putative Rru_A1442 8 None None None 83593674 Common - ABC transporter component Rru_A2339 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83591521 Nonpathogen - hypothetical protein Rru_A0181 2 None None None 83593873 Nonpathogen - hypothetical protein Rru_A2538 1 None None None 83593488 Common - TonB-like Rru_A2153 45 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 83592790 Common - Phage Tail Collar Rru_A1454 36 COG4675 MdpB, Microcystin-dependent protein Function unknown 83591406 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Rru_A0066 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83592976 Common - cation antiporter Rru_A1641 49 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 83594835 Common - putative branched-chain amino acid transport system substrate-binding protein Rru_A3506 65 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83594339 Common - Aminotransferase class-III Rru_A3009 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 83594676 Common - Glycosyl transferase, group 1 Rru_A3347 212 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83592659 Common - Malonate decarboxylase delta subunit Rru_A1323 21 None None None 83592725 Nonpathogen - NAD(+)--dinitrogen-reductase ADP-D-ribosyltransferase Rru_A1389 11 None None None 83592867 Nonpathogen - TPR repeat Rru_A1532 4 None None None 83594417 Nonpathogen - hypothetical protein Rru_A3087 2 None None None 83592083 Common - 2-nitropropane dioxygenase, NPD Rru_A0744 147 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 83594381 Common - Glycine cleavage system T protein Rru_A3051 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 83592939 Common - Alpha amylase, catalytic region Rru_A1604 93 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83591973 Common - Cyclic nucleotide-binding domain (cNMP-BD) protein Rru_A0634 65 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 83591773 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Rru_A0433 146 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 83591431 Common - PilT protein-like Rru_A0091 55 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 83594064 Common - hypothetical protein Rru_A2732 25 COG0433 COG0433, Predicted ATPase General function prediction only 83594657 Common - OmpA/MotB Rru_A3328 127 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83592121 Common - hypothetical protein Rru_A0782 3 None None None 83592475 Common - Blue (type 1) copper subtype Rru_A1139 31 COG3794 PetE, Plastocyanin Energy production and conversion 83591650 Common - Ferredoxin hydrogenase Rru_A0310 68 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 83591391 Common - Carboxyl transferase Rru_A0051 215 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 83594264 Nonpathogen - hypothetical protein Rru_A2932 1 None None None 83593175 Common - Penicillin amidase Rru_A1840 77 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 83594124 Common thyX FAD-dependent thymidylate synthase Rru_A2792 50 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 83593402 Nonpathogen - Acyltransferase 3 Rru_A2067 5 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 83592124 Common - Transcriptional Regulator, LysR family Rru_A0785 138 COG0583 LysR, Transcriptional regulator Transcription 83592715 Common - Acetate kinase Rru_A1379 161 COG0282 ackA, Acetate kinase Energy production and conversion 83593962 Common - ROK Rru_A2630 149 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 83591483 Nonpathogen - GCN5-related N-acetyltransferase Rru_A0143 5 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 83594753 Common - Orotidine-5'-phosphate decarboxylase Rru_A3424 155 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 83592055 Common - adenylosuccinate lyase Rru_A0716 237 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 83594194 Common - Alpha/beta hydrolase fold Rru_A2862 32 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83592940 Common - Alpha amylase, catalytic region Rru_A1605 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 83591565 Common - Metal dependent phosphohydrolase, HD region Rru_A0225 31 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 83592242 Common - polyhedral shell protein, EutL/PduB type Rru_A0906 16 COG4816 EutL, Ethanolamine utilization protein Amino acid transport and metabolism 83594818 Nonpathogen - hypothetical protein Rru_A3489 3 None None None 83591862 Common - chemotaxis-specific methylesterase Rru_A0523 206 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 83591957 Common - PUCC protein Rru_A0618 23 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83591613 Common - Acetoacetyl-CoA reductase Rru_A0273 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83591550 Common rpmB 50S ribosomal protein L28 Rru_A0210 133 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 83591630 Common - Auxin Efflux Carrier Rru_A0290 60 COG0679 COG0679, Predicted permeases General function prediction only 83593269 Common - Transcriptional Regulator, TetR family Rru_A1934 74 COG1309 AcrR, Transcriptional regulator Transcription 83591903 Nonpathogen - hypothetical protein Rru_A0564 1 None None None 83594358 Common - Asparagine synthase Rru_A3028 90 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83593104 Common - Acid phosphatase Rru_A1769 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 83594847 Common - 2-dehydropantoate 2-reductase Rru_A3518 82 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 83594849 Common - hypothetical protein Rru_A3520 150 COG0628 PerM, Predicted permease General function prediction only 83592846 Nonpathogen - PRC-barrel Rru_A1510 2 None None None 83591463 Common - RfaE-HldE bifunctional protein, D-beta-D-heptose 7-phosphate kinase, D-beta-D-heptose 1-phosphate adenosyltransferase Rru_A0123 130 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 83593895 Common - Transglutaminase-like Rru_A2560 87 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 83593946 Common - Transcriptional Regulator, XRE family with Cupin sensor domain Rru_A2614 78 COG1396 HipB, Predicted transcriptional regulators Transcription 83592455 Common - NnrS Rru_A1119 53 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 83594585 Common - Protein of unknown function DUF214 Rru_A3255 33 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 83592102 Common - Radical SAM Rru_A0763 110 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 83594534 Common - C-terminal processing peptidase Rru_A3204 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 83593150 Common - Glycolate reductase Rru_A1815 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 83592902 Common - NADH dehydrogenase subunit M Rru_A1567 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 83593072 Nonpathogen - hypothetical protein Rru_A1737 1 None None None 83594604 Nonpathogen - hypothetical protein Rru_A3274 5 None None None 83594377 Nonpathogen - hypothetical protein Rru_A3047 1 None None None 83592463 Common - ISBm1, transposase orfB Rru_A1127 57 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83593492 Common - CHAP Rru_A2157 12 None None None 83591745 Common - Colicin V production protein Rru_A0405 16 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 83594715 Common - BioY protein Rru_A3386 63 COG1268 BioY, Uncharacterized conserved protein General function prediction only 83591668 Common - Lysine exporter protein (LYSE/YGGA) Rru_A0328 102 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83593935 Common - Two Component Transcriptional Regulator, LuxR family Rru_A2603 176 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 83592726 Common - hypothetical protein Rru_A1390 18 None None None 83593170 Common - Butyryl-CoA dehydrogenase Rru_A1835 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83594269 Common - Asparagine synthase, glutamine-hydrolyzing Rru_A2937 148 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83593936 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Rru_A2604 173 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83591689 Common - hypothetical protein Rru_A0349 10 None None None 83591837 Common - ABC transporter component Rru_A0497 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 83595017 Common - ABC transporter component Rru_A3688 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 83593422 Common - extracellular solute-binding protein, family 3 Rru_A2087 138 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83591640 Common - aminotransferase Rru_A0300 183 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 83594423 Common - Membrane protein involved in the export of O-antigen and teichoic acid-like Rru_A3093 24 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 83592626 Common - hypothetical protein Rru_A1290 5 None None None 83592465 Common - Ammonium transporter Rru_A1129 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 83592259 Common - hypothetical protein Rru_A0923 10 None None None 83594910 Common - Transcriptional coactivator/pterin dehydratase Rru_A3581 115 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 83594254 Nonpathogen - hypothetical protein Rru_A2922 1 None None None 83593107 Common - Twin-arginine translocation protein TatB Rru_A1772 25 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 83594312 Common - O-methyltransferase, family 2 Rru_A2982 32 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 83594795 Common rocD ornithine--oxo-acid transaminase Rru_A3466 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 83594878 Common - cobyric acid synthase Rru_A3549 151 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 83591526 Nonpathogen - hypothetical protein Rru_A0186 1 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 83593374 Common - hypothetical protein Rru_A2039 65 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 83591551 Nonpathogen - hypothetical protein Rru_A0211 11 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 83593669 Common - nucleoside-diphosphate-sugar epimerase Rru_A2334 45 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83594213 Common - virulence protein Rru_A2881 19 COG3946 VirJ, Type IV secretory pathway, VirJ component Intracellular trafficking and secretion 83593161 Common - hypothetical protein Rru_A1826 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 83592284 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Rru_A0948 142 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 83594274 Common - ABC transporter, transmembrane region Rru_A2942 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83592237 Common - hypothetical protein Rru_A0901 24 None None None 83592931 Common - Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Rru_A1596 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 83594248 Common - 4'-phosphopantetheinyl transferase Rru_A2916 58 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 83594302 Common - Peptidase M16-like Rru_A2972 191 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 83591844 Common - Glycogen debranching enzyme GlgX Rru_A0505 157 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 83591433 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0093 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 83592949 Nonpathogen - hypothetical protein Rru_A1614 1 None None None 83593318 Common - hypothetical protein Rru_A1983 19 None None None 83593064 Common - Protein of unknown function DUF502 Rru_A1729 78 COG2928 COG2928, Uncharacterized conserved protein Function unknown 83591925 Common - Chaperonin Cpn10 Rru_A0586 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 83594103 Common hisD histidinol dehydrogenase Rru_A2771 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 83591643 Nonpathogen - hypothetical protein Rru_A0303 1 None None None 83591651 Common - Formate/nitrite transporter Rru_A0311 97 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 83593261 Common - hypothetical protein Rru_A1926 31 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 83593204 Common - Phosphatidylglycerophosphatase A Rru_A1869 105 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 83594885 Common - hypothetical protein Rru_A3556 31 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 83592593 Common - hypothetical protein Rru_A1257 4 None None None 83592378 Common - hypothetical protein Rru_A1042 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 83591928 Common - Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like Rru_A0589 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83593635 Common - inner-membrane translocator Rru_A2300 104 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 83595086 Common - Excisionase/Xis, DNA-binding Rru_A3757 4 None None None 83593242 Common - Protein-methionine-S-oxide reductase Rru_A1907 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 83592370 Common - Multi-sensor Signal Transduction Histidine Kinase Rru_A1034 133 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83594692 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Rru_A3363 219 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 83594611 Common - Delta 1-pyrroline-5-carboxylate reductase Rru_A3281 209 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 83591911 Common - 4-hydroxybenzoate polyprenyl transferase Rru_A0572 175 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 83592134 Common - Nitrogenase iron protein Rru_A0795 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 83594825 Common - chemotaxis sensory transducer Rru_A3496 25 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594449 Common - ATPases involved in chromosome partitioning-like Rru_A3119 122 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83593855 Common - Penicillin-binding protein 1A Rru_A2520 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 83591872 Common - GTP-binding signal recognition particle SRP54, G-domain Rru_A0533 195 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 83591852 Common - Protein of unknown function DUF952 Rru_A0513 46 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 83591417 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A0077 155 COG1146 COG1146, Ferredoxin Energy production and conversion 83594524 Common - SMF protein Rru_A3194 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 83592206 Common - OmpA/MotB Rru_A0870 114 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 83593924 Nonpathogen - hypothetical protein Rru_A2592 2 None None None 83592070 Nonpathogen - hypothetical protein Rru_A0731 1 None None None 83594621 Common - hypothetical protein Rru_A3291 11 None None None 83593918 Nonpathogen - hypothetical protein Rru_A2586 1 None None None 83594432 Common - sugar transferase Rru_A3102 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 83591356 Common - 3-beta-hydroxy-delta(5)-steroid dehydrogenase Rru_A0016 149 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83594893 Common - Histidinol-phosphate phosphatase Rru_A3564 125 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 83591966 Common - bacteriochlorophyll/chlorophyll a synthase Rru_A0627 71 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 83594514 Common - hypothetical protein Rru_A3184 13 None None None 83592554 Common - phage shock protein A, PspA Rru_A1218 78 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 83592545 Common - Chromate transporter Rru_A1209 62 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 83593974 Common - Alpha/beta hydrolase fold Rru_A2642 61 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83591939 Common - Phosphate transport system permease protein 2 Rru_A0600 219 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 83592806 Nonpathogen - hypothetical protein Rru_A1470 1 None None None 83593252 Common - extracellular solute-binding protein, family 5 Rru_A1917 198 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 83594095 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Rru_A2763 181 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83593578 Nonpathogen - hypothetical protein Rru_A2243 2 COG3458 COG3458, Acetyl esterase (deacetylase) Secondary metabolites biosynthesis, transport, and catabolism 83593033 Common - Cation efflux protein Rru_A1698 151 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 83593514 Common - Transcriptional Regulator, LuxR family Rru_A2179 40 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 83591983 Common - hypothetical protein Rru_A0644 4 None None None 83595027 Common - Outer membrane lipoprotein carrier protein LolA Rru_A3698 41 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 83591698 Common - Heme oxygenase Rru_A0358 14 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 83595021 Common - hypothetical protein Rru_A3692 32 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 83592398 Common - PilT protein-like Rru_A1062 20 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 83592873 Nonpathogen - hypothetical protein Rru_A1538 4 None None None 83592997 Common - SmpA/OmlA Rru_A1662 35 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 83594995 Common - hypothetical protein Rru_A3666 2 None None None 83591760 Nonpathogen - hypothetical protein Rru_A0420 1 None None None 83592118 Common - extracellular solute-binding protein, family 3 Rru_A0779 121 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83592033 Common - Response regulator receiver (CheY) and unknown domain protein Rru_A0694 65 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 83595081 Common - Protein of unknown function DUF302 Rru_A3752 34 COG3439 COG3439, Uncharacterized conserved protein Function unknown 83594581 Common - A/G-specific adenine glycosylase MutY Rru_A3251 214 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 83592035 Common - RNA methyltransferase TrmH, group 1 Rru_A0696 156 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 83594004 Common - Ribosomal protein L18 Rru_A2672 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 83594083 Common - hypothetical protein Rru_A2751 53 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 83594215 Common - DNA primase Rru_A2883 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 83592488 Nonpathogen - hypothetical protein Rru_A1152 2 None None None 83594754 Common - N-(5'-phosphoribosyl)anthranilate isomerase Rru_A3425 197 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 83593545 Common - Phosphoglycerate/bisphosphoglycerate mutase Rru_A2210 142 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 83592619 Common - Membrane-bound tetrahaem cytochrome TorC/YecK Rru_A1283 46 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 83592679 Common - hypothetical protein Rru_A1343 32 COG5476 COG5476, Uncharacterized conserved protein Function unknown 83594030 Common rplA 50S ribosomal protein L1 Rru_A2698 246 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 83591954 Nonpathogen - photosynthetic complex assembly protein Rru_A0615 6 None None None 83593765 Common - Plasmid maintenance system antidote protein Rru_A2430 82 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 83593947 Common - Transcriptional Regulator, ArsR family Rru_A2615 146 COG0640 ArsR, Predicted transcriptional regulators Transcription 83592445 Common - chemotaxis sensory transducer Rru_A1109 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594034 Common - elongation factor Tu Rru_A2702 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 83593295 Common - O-methyltransferase, family 3 Rru_A1960 85 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 83592830 Common - hypothetical protein Rru_A1494 2 None None None 83591344 Common gyrB DNA gyrase subunit B Rru_A0004 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 83594940 Common - DNA polymerase III, epsilon subunit Rru_A3611 190 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 83592474 Common - ABC transporter component Rru_A1138 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 83594628 Nonpathogen - hypothetical protein Rru_A3298 1 None None None 83594008 Common rplE 50S ribosomal protein L5 Rru_A2676 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 83593796 Common - CHAP Rru_A2461 12 None None None 83591682 Nonpathogen - hypothetical protein Rru_A0342 2 None None None 83592890 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Rru_A1555 160 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 83592702 Common - Transcriptional Regulator, DeoR family Rru_A1366 63 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 83593865 Nonpathogen - hypothetical protein Rru_A2530 1 None None None 83594548 Nonpathogen - hypothetical protein Rru_A3218 1 None None None 83593954 Nonpathogen - hypothetical protein Rru_A2622 1 None None None 83594282 Common - Farnesyltranstransferase Rru_A2950 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 83592938 Common - PhoH-like protein Rru_A1603 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 83594228 Common - Transcriptional Regulator, AsnC family Rru_A2896 158 COG1522 Lrp, Transcriptional regulators Transcription 83592249 Common - Protein of unknown function DUF336 Rru_A0913 35 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 83592770 Common - quinolinate synthetase Rru_A1434 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 83592313 Common - hypothetical protein Rru_A0977 4 None None None 83593214 Common - Dihydrolipoamide acetyltransferase, long form Rru_A1879 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 83593632 Common - Ribokinase Rru_A2297 187 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 83591386 Common - Protein of unknown function DUF523 Rru_A0046 57 COG1683 COG1683, Uncharacterized conserved protein Function unknown 83592014 Nonpathogen - hypothetical protein Rru_A0675 1 None None None 83593902 Common - Cysteine desulphurases, SufS Rru_A2570 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 83594641 Common - Plasmid maintenance system antidote protein Rru_A3311 63 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 83591769 Common gmk guanylate kinase Rru_A0429 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 83595095 Common - Transcriptional Regulator, MucR family Rru_A3766 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 83594541 Common - Hemerythrin HHE cation binding region Rru_A3211 27 COG2703 COG2703, Hemerythrin Inorganic ion transport and metabolism 83595014 Common - Transcriptional Regulator, AsnC family Rru_A3685 152 COG1522 Lrp, Transcriptional regulators Transcription 83592350 Nonpathogen - hypothetical protein Rru_A1014 1 None None None 83592154 Common - Transposase, mutator type Rru_A0817 80 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 83592760 Nonpathogen - NADH dehydrogenase (ubiquinone), 30 kDa subunit Rru_A1424 6 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 83594156 Common fliE flagellar hook-basal body protein FliE Rru_A2824 27 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 83592363 Common - (Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase Rru_A1027 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 83594952 Nonpathogen - hypothetical protein Rru_A3623 13 None None None 83592000 Common - Hly-III related proteins Rru_A0661 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 83592333 Common - NifZ Rru_A0997 26 None None None 83594016 Common - Ribosomal protein S19 Rru_A2684 242 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 83594983 Common - Protein of unknown function DUF74 Rru_A3654 59 COG0393 COG0393, Uncharacterized conserved protein Function unknown 83593741 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) and Response Regulator Receiver modulation Rru_A2406 226 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83594256 Nonpathogen - Glycosyl transferase, family 2 Rru_A2924 3 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 83593722 Common - ABC transporter, periplasmic substrate-binding protein, putative Rru_A2387 3 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 83593157 Common - 6,7-dimethyl-8-ribityllumazine synthase Rru_A1822 207 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 83592253 Common - S-adenosylmethionine synthetase Rru_A0917 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 83595051 Nonpathogen - hypothetical protein Rru_A3722 3 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 83593808 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Rru_A2473 202 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83594775 Common - HPrNtr Rru_A3446 155 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 83595056 Common - inner-membrane translocator Rru_A3727 128 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 83592654 Nonpathogen - hypothetical protein Rru_A1318 3 None None None 83592769 Common - L-aspartate oxidase Rru_A1433 222 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 83594066 Common - dTDP-4-dehydrorhamnose reductase Rru_A2734 127 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 83591591 Common - Transcriptional Regulator, AraC family Rru_A0251 113 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83594309 Nonpathogen - Chlorophyllide reductase subunit Y Rru_A2979 15 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83593293 Common - GMP reductase Rru_A1958 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 83593691 Common - extracellular solute-binding protein, family 5 Rru_A2356 209 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 83592024 Common - Protein of unknown function DUF81 Rru_A0685 14 None None None 83592818 Common - Undecaprenyl-phosphate galactosephosphotransferase Rru_A1482 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 83594925 Common - Imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Rru_A3596 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 83593625 Common - bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein Rru_A2290 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 83591531 Common - Aspartate 1-decarboxylase-like Rru_A0191 7 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 83593443 Common - Multi-sensor Hybrid Histidine Kinase Rru_A2108 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83594592 Common - hypothetical protein Rru_A3262 15 COG4995 COG4995, Uncharacterized protein conserved in bacteria Function unknown 83594741 Common - Amidohydrolase Rru_A3412 72 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 83594889 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Rru_A3560 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83594842 Common - chemotaxis sensory transducer Rru_A3513 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593730 Common - TonB-dependent siderophore receptor Rru_A2395 116 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 83594904 Common - Acetate--CoA ligase Rru_A3575 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 83593135 Nonpathogen - Prevent-host-death protein Rru_A1800 5 None None None 83594856 Common - Protein of unknown function YGGT Rru_A3527 124 COG0762 COG0762, Predicted integral membrane protein Function unknown 83591619 Common - 4Fe-4S ferredoxin, iron-sulfur binding Rru_A0279 132 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 83592710 Common - Peptidase C14, caspase catalytic subunit p20 Rru_A1374 15 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 83593123 Common - Response regulator receiver domain protein (CheY) Rru_A1788 21 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83593597 Common - hypothetical protein Rru_A2262 30 COG5458 COG5458, Uncharacterized conserved protein Function unknown 83591895 Common - Formyltetrahydrofolate deformylase Rru_A0556 220 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 83594667 Common - Protein of unknown function DUF37 Rru_A3338 182 COG0759 COG0759, Uncharacterized conserved protein Function unknown 83593481 Common - chemotaxis sensory transducer Rru_A2146 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592195 Common - Secretion protein HlyD Rru_A0859 138 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83592172 Common - hypothetical protein Rru_A0836 5 None None None 83594177 Common flgH flagellar basal body L-ring protein Rru_A2845 101 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 83591701 Common - 5'-methylthioadenosine phosphorylase Rru_A0361 141 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 83592695 Common - Ribose/galactose isomerase Rru_A1359 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 83592394 Common - putative thioesterase Rru_A1058 46 COG0824 FcbC, Predicted thioesterase General function prediction only 83592080 Common - Signal Transduction Histidine Kinase Rru_A0741 54 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 83591795 Common - NUDIX hydrolase Rru_A0455 6 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83593603 Common - Nitrogen fixation protein NifW Rru_A2268 22 None None None 83593783 Common - Protein of unknown function DUF330 Rru_A2448 29 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 83591771 Common ksgA dimethyladenosine transferase Rru_A0431 245 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 83593996 Common - DNA-directed RNA polymerase subunit alpha Rru_A2664 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 83594798 Nonpathogen - hypothetical protein Rru_A3469 1 None None None 83592989 Common - Response regulator receiver domain protein (CheY) Rru_A1654 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83593311 Common - Phenylacetate--CoA ligase Rru_A1976 125 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 83591706 Common - Polynucleotide adenylyltransferase region Rru_A0366 182 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 83591737 Common - argininosuccinate lyase Rru_A0397 225 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 83593023 Common - hypothetical protein Rru_A1688 20 COG3644 COG3644, Uncharacterized protein conserved in bacteria Function unknown 83594097 Common - GCN5-related N-acetyltransferase Rru_A2765 15 COG0456 RimI, Acetyltransferases General function prediction only 83591712 Common - hypothetical protein Rru_A0372 32 COG5426 COG5426, Uncharacterized membrane protein Function unknown 83594364 Common - Protein of unknown function DUF6, transmembrane Rru_A3034 51 None None None 83593576 Common - hypothetical protein Rru_A2241 18 None None None 83592951 Common - cysteine synthase A Rru_A1616 223 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 83592614 Common - Sulfotransferase Rru_A1278 15 None None None 83591437 Common - Class I peptide chain release factor Rru_A0097 110 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 83591519 Common - Protein of unknown function DUF83 Rru_A0179 97 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83593011 Common - Dihydrouridine synthase TIM-barrel protein nifR3 Rru_A1676 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 83594967 Common - Two component Transcriptional regulator, Winged helix family Rru_A3638 142 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83592936 Common gltX glutamyl-tRNA synthetase Rru_A1601 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 83591542 Common - Phospholipase D/Transphosphatidylase Rru_A0202 97 COG0398 COG0398, Uncharacterized conserved protein Function unknown 83593088 Common - High-affinity nickel-transporter Rru_A1753 28 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 83592471 Common - Aminotransferase, class I and II Rru_A1135 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83593391 Common - Carbonate dehydratase Rru_A2056 148 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 83592329 Common - Transcriptional Regulator, NifA, Fis Family Rru_A0993 169 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 83592022 Common - 3-deoxy-7-phosphoheptulonate synthase Rru_A0683 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 83594500 Common - Surface presentation of antigens (SPOA) protein Rru_A3170 121 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 83591610 Common apaG ApaG Rru_A0270 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 83593386 Common - Hydrophobe/amphiphile efflux-1 HAE1 Rru_A2051 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83592264 Common - Hydrogenase expression/synthesis, HypA Rru_A0928 95 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 83594865 Common - Nitroreductase Rru_A3536 106 COG0778 NfnB, Nitroreductase Energy production and conversion 83591390 Nonpathogen - hypothetical protein Rru_A0050 1 None None None 83591497 Common - Drug resistance transporter EmrB/QacA subfamily Rru_A0157 188 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83591367 Common - Monofunctional biosynthetic peptidoglycan transglycosylase Rru_A0027 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 83595124 Common - Transcriptional Regulator, BadM/Rrf2 family Rru_A3795 113 COG1959 COG1959, Predicted transcriptional regulator Transcription 83593266 Common - Ferredoxin--nitrite reductase Rru_A1931 173 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 83592040 Common rpsD 30S ribosomal protein S4 Rru_A0701 225 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 83594085 Common - Transglutaminase-like Rru_A2753 92 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 83594207 Common - Transcriptional Regulator, LysR family Rru_A2875 132 COG0583 LysR, Transcriptional regulator Transcription 83594258 Common - RND efflux system, outer membrane lipoprotein, NodT Rru_A2926 108 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 83592347 Common - Nitrogenase molybdenum-iron protein alpha chain Rru_A1011 53 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83592111 Common - Oxidoreductase/nitrogenase, component 1 Rru_A0772 57 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83592503 Common - putative hydrogenase expression/formation protein HupK Rru_A1167 49 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 83593419 Common - hypothetical protein Rru_A2084 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83593886 Common - Protein of unknown function DUF218 Rru_A2551 36 COG1434 COG1434, Uncharacterized conserved protein Function unknown 83593301 Nonpathogen - Coenzyme F390 synthetase-like Rru_A1966 1 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 83592522 Common - 16S rRNA processing protein RimM Rru_A1186 72 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 83591810 Common - Cell shape determining protein MreB/Mrl Rru_A0470 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 83594916 Nonpathogen - hypothetical protein Rru_A3587 1 None None None 83593724 Common - ABC transporter component Rru_A2389 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 83594475 Common mdoD glucan biosynthesis protein D Rru_A3145 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 83592744 Common - chemotaxis sensory transducer Rru_A1408 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594704 Common - Glycosyl transferase, family 9 Rru_A3375 58 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 83593031 Common - permease Rru_A1696 8 None None None 83594502 Common - Lysine exporter protein (LYSE/YGGA) Rru_A3172 73 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 83594721 Nonpathogen - hypothetical protein Rru_A3392 3 COG4710 COG4710, Predicted DNA-binding protein with an HTH domain General function prediction only 83593361 Common - Ferredoxin Rru_A2026 101 COG0633 Fdx, Ferredoxin Energy production and conversion 83593771 Common aat leucyl/phenylalanyl-tRNA--protein transferase Rru_A2436 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 83592539 Common - Succinate dehydrogenase, cytochrome b subunit Rru_A1203 42 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 83592799 Common - Sulfotransferase Rru_A1463 15 None None None 83594633 Common - amide-urea binding protein Rru_A3303 85 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83592109 Common - Peptidase M23B Rru_A0770 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83594404 Common - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family-like Rru_A3074 13 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 83592801 Common - hypothetical protein Rru_A1465 15 None None None 83592851 Common - Transposase and inactivated derivatives-like Rru_A1516 62 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 83592894 Common - NADH dehydrogenase (ubiquinone) Rru_A1559 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 83594546 Common - hypothetical protein Rru_A3216 109 COG5283 COG5283, Phage-related tail protein Function unknown 83593371 Nonpathogen - hypothetical protein Rru_A2036 12 None None None 83594061 Common - hypothetical protein Rru_A2729 12 COG5589 COG5589, Uncharacterized conserved protein Function unknown 83592633 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Rru_A1297 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83594121 Common - Major facilitator superfamily protein MFS_1 Rru_A2789 188 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83594578 Common - Chromosome segregation protein SMC Rru_A3248 176 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83594666 Common - ribonuclease P protein Rru_A3337 24 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 83595110 Common infB translation initiation factor IF-2 Rru_A3781 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 83594686 Common - Transcriptional Regulator, AraC family Rru_A3357 123 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 83594805 Common - Transcriptional Regulator, LysR family Rru_A3476 128 COG0583 LysR, Transcriptional regulator Transcription 83591767 Common - Short-chain dehydrogenase/reductase SDR Rru_A0427 183 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 83594860 Common - Nitrogen-fixing NifU-like Rru_A3531 100 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 83592357 Common - RNA polymerase factor sigma-32 Rru_A1021 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 83593323 Common - GCN5-related N-acetyltransferase Rru_A1988 67 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 83593433 Common - Protein of unknown function DUF490 Rru_A2098 99 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 83591901 Common - Peptidase S1 and S6, chymotrypsin/Hap Rru_A0562 26 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 83591549 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Rru_A0209 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 83591399 Common - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Rru_A0059 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 83593144 Common - Sigma-24 (FecI) Rru_A1809 23 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83594235 Common - Deoxyribodipyrimidine photolyase Rru_A2903 137 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 83594386 Common - Major facilitator superfamily MFS_1 Rru_A3056 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83591636 Common - hypothetical protein Rru_A0296 18 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 83594133 Common - thiol-disulfide interchange protein Rru_A2801 144 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 83591723 Common - SH3 domain protein Rru_A0383 9 None None None 83593044 Common - PilT protein-like Rru_A1709 41 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 83592910 Nonpathogen - hypothetical protein Rru_A1575 1 None None None 83594139 Common - YHS Rru_A2807 17 COG4393 COG4393, Predicted membrane protein Function unknown 83592335 Common - hypothetical protein Rru_A0999 19 None None None 83593458 Common - hypothetical protein Rru_A2123 83 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83592919 Common - chemotaxis sensory transducer Rru_A1584 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593536 Common - Peptidase S1C, Do Rru_A2201 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 83591854 Common - HAD-superfamily subfamily IIA hydrolase Rru_A0515 53 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 83593041 Common - Lytic murein transglycosylase Rru_A1706 107 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 83593181 Common - Twin-arginine translocation pathway signal Rru_A1846 87 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 83594029 Common - Ribosomal protein L10 Rru_A2697 215 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 83593818 Common - 5'-Nucleotidase Rru_A2483 135 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 83591605 Common - Electron-transferring-flavoprotein dehydrogenase Rru_A0265 114 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 83594101 Common - Protein tyrosine phosphatase Rru_A2769 101 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 83592589 Common - Glutamine synthetase, catalytic region Rru_A1253 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 83592889 Common - chemotaxis sensory transducer Rru_A1554 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593801 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Rru_A2466 126 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 83594396 Common - NAD(P)H dehydrogenase (quinone) Rru_A3066 89 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 83593063 Common - ATP-dependent DNA helicase RecG Rru_A1728 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 83593307 Common - Phosphoenolpyruvate-protein phosphotransferase Rru_A1972 233 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 83591746 Common - DNA repair protein RadA Rru_A0406 202 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 83591559 Common - hypothetical protein Rru_A0219 13 None None None 83594117 Common - ABC transporter component Rru_A2785 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 83592340 Common - Lysine-arginine-ornithine-binding periplasmic protein Rru_A1004 119 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83592484 Common - hypothetical protein Rru_A1148 5 None None None 83595100 Common - PhoH-like protein Rru_A3771 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 83592603 Common - Carbohydrate kinase, FGGY Rru_A1267 181 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 83595035 Common - Aminotransferase, class I and II Rru_A3706 232 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 83592320 Common - Peptidase M20D, amidohydrolase Rru_A0984 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 83595065 Common - hypothetical protein Rru_A3736 29 COG5654 COG5654, Uncharacterized conserved protein Function unknown 83592783 Common - Arsenite-transporting ATPase Rru_A1447 94 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 83594949 Common - Zinc-containing alcohol dehydrogenase superfamily Rru_A3620 176 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83593987 Common - intracellular septation protein A Rru_A2655 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 83594653 Common - copper-translocating P-type ATPase Rru_A3324 230 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 83592069 Common - hypothetical protein Rru_A0730 8 None None None 83594977 Common - Aminoglycoside phosphotransferase Rru_A3648 70 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 83595107 Common - Protein of unknown function DUF150 Rru_A3778 167 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 83592456 Common - ABC transporter, transmembrane region Rru_A1120 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 83592402 Common - ABC transporter component Rru_A1066 243 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 83591624 Common - acetolactate synthase 2 catalytic subunit Rru_A0284 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 83591869 Common - Ferredoxin--NADP+ reductase Rru_A0530 105 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 83592081 Common - 3-demethylubiquinone-9 3-methyltransferase Rru_A0742 112 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 83593961 Common - Beta-lactamase-like Rru_A2629 81 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 83591465 Nonpathogen - diguanylate phosphodiesterase (EAL domain) Rru_A0125 2 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 83592730 Common - nitrogenase iron-iron protein, alpha chain Rru_A1394 57 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83594180 Nonpathogen fliX flagellar assembly regulator FliX Rru_A2848 9 None None None 83594965 Nonpathogen - hypothetical protein Rru_A3636 2 None None None 83594337 Common - SOUL heme-binding protein Rru_A3007 26 None None None 83592142 Common - ABC transporter component Rru_A0803 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83591786 Nonpathogen - hypothetical protein Rru_A0446 1 None None None 83591490 Common - hypothetical protein Rru_A0150 26 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 83592495 Common - Two component Transcriptional regulator, Winged helix family Rru_A1159 210 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83595074 Common - hypothetical protein Rru_A3745 15 None None None 83593018 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Rru_A1683 14 COG0546 Gph, Predicted phosphatases General function prediction only 83591999 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Rru_A0660 217 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83594024 Common - 30S ribosomal protein S7 Rru_A2692 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 83592786 Common - Transcriptional Regulator, ArsR family Rru_A1450 191 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 83593715 Common - Major facilitator superfamily MFS_1 Rru_A2380 75 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 83594461 Common - Secretion protein HlyD Rru_A3131 117 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 83594059 Common - hypothetical protein Rru_A2727 37 COG5473 COG5473, Predicted integral membrane protein Function unknown 83593177 Common - motA, chemotaxis (motility protein A Rru_A1842 105 COG1291 MotA, Flagellar motor component Cell motility and secretion 83592743 Common - CheD, stimulates methylation of MCP proteins Rru_A1407 86 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 83594670 Common - acetylglutamate kinase Rru_A3341 217 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 83592388 Common - Response regulator receiver domain protein (CheY) Rru_A1052 25 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83591358 Common - putative oxidoreductase Rru_A0018 194 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 83593929 Common - Iron permease FTR1 Rru_A2597 55 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 83593478 Common - methyltransferase Rru_A2143 37 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 83591404 Common - squalene-phytoene synthase Rru_A0064 111 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 83593563 Common - Putative diguanylate cyclase (GGDEF domain) Rru_A2228 167 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 83594319 Common - Precorrin-3B C17-methyltransferase region Rru_A2989 119 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 83593258 Common - Lipid A biosynthesis-like Rru_A1923 24 COG3952 COG3952, Predicted membrane protein Function unknown 83591820 Nonpathogen - hypothetical protein Rru_A0480 1 None None None 83593427 Nonpathogen - hypothetical protein Rru_A2092 1 None None None 83592090 Common - Modification methylase HemK Rru_A0751 215 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 83595119 Common - Glycolate reductase Rru_A3790 225 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 83592296 Common - AmpD (negative regulator of AmpC) Rru_A0960 111 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 83594342 Common - Binding-protein-dependent transport systems inner membrane component Rru_A3012 202 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 83593298 Common - Adenylosuccinate lyase Rru_A1963 240 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 83594522 Common - Protein of unknown function DUF205 Rru_A3192 136 COG0344 COG0344, Predicted membrane protein Function unknown 83591587 Common - Periplasmic binding protein/LacI transcriptional regulator Rru_A0247 97 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83591507 Common - hypothetical protein Rru_A0167 8 None None None 83593862 Nonpathogen - hypothetical protein Rru_A2527 1 None None None 83592099 Common - hypothetical protein Rru_A0760 35 None None None 83592221 Common - TonB-dependent siderophore receptor Rru_A0885 125 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 83592923 Common - Uridylate kinase Rru_A1588 242 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 83591829 Common - Periplasmic binding protein Rru_A0489 51 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 83592758 Common - NADH ubiquinone oxidoreductase, 20 kDa subunit Rru_A1422 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 83592572 Common - Iojap-related protein Rru_A1236 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 83594421 Common - Glycosyl transferase, group 1 Rru_A3091 104 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83594012 Common - Ribosomal protein L29 Rru_A2680 155 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 83593686 Common - Macrocin-O-methyltransferase Rru_A2351 21 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 83592219 Common - Sigma-24 (FecI) Rru_A0883 125 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83593523 Nonpathogen - hypothetical protein Rru_A2188 1 None None None 83594907 Common - hypothetical protein Rru_A3578 9 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 83594932 Common - Protein of unknown function DUF162 Rru_A3603 78 COG1556 COG1556, Uncharacterized conserved protein Function unknown 83592705 Nonpathogen - hypothetical protein Rru_A1369 1 None None None 83595067 Common - Phage integrase Rru_A3738 216 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 83595082 Common - hypothetical protein Rru_A3753 10 None None None 83593620 Common - Nitrogenase molybdenum-iron cofactor biosynthesis protein Rru_A2285 48 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 83591474 Common - Succinic semialdehyde dehydrogenase Rru_A0134 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83593490 Common - MotA/TolQ/ExbB proton channel Rru_A2155 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 83594942 Common - Quinate/Shikimate 5-dehydrogenase Rru_A3613 206 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 83594816 Common - Threonyl-tRNA synthetase, class IIa Rru_A3487 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83592076 Common - Phosphoribosyltransferase Rru_A0737 94 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 83594713 Common - Precorrin-4 C11-methyltransferase region Rru_A3384 201 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 83592645 Common - acetoacetyl-CoA reductase Rru_A1309 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 83593074 Common - hypothetical protein Rru_A1739 44 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 83593468 Common - glucosyltransferase MdoH Rru_A2133 55 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 83594926 Common - Imidazoleglycerol-phosphate dehydratase Rru_A3597 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 83592579 Common - Cytochrome B561 Rru_A1243 45 COG3658 COG3658, Cytochrome b Energy production and conversion 83594126 Common - Deoxycytidine triphosphate deaminase Rru_A2794 153 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 83591512 Common - CRISPR-associated CT1975 family protein Rru_A0172 42 None None None 83592189 Common - hypothetical protein Rru_A0853 11 None None None 83593263 Common - 2-isopropylmalate synthase Rru_A1928 210 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 83593234 Common - Nucleoside recognition Rru_A1899 18 COG3366 COG3366, Uncharacterized protein conserved in archaea Function unknown 83592381 Common - hypothetical protein Rru_A1045 26 COG5590 COG5590, Uncharacterized conserved protein Function unknown 83591580 Common - NUDIX hydrolase Rru_A0240 39 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 83593277 Common - Enoyl-CoA hydratase/isomerase Rru_A1942 175 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 83591510 Common - CRISPR-associated CT1974 family protein Rru_A0170 30 None None None 83593847 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Rru_A2512 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83592276 Common - DNA repair protein RecN Rru_A0940 198 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 83592667 Common - ABC transporter component Rru_A1331 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 83592670 Common - Ribose 5-phosphate isomerase B Rru_A1334 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 83591505 Nonpathogen - hypothetical protein Rru_A0165 1 None None None 83594551 Common - hypothetical protein Rru_A3221 17 None None None 83594497 Common - Binding-protein-dependent transport systems inner membrane component Rru_A3167 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 83592434 Common - Peptidase M41, FtsH Rru_A1098 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 83593203 Common - Peptidase M23B Rru_A1868 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 83593081 Common - Extracellular ligand-binding receptor Rru_A1746 149 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83591637 Common - Putative esterase Rru_A0297 65 COG0627 COG0627, Predicted esterase General function prediction only 83592038 Common - Plasmid stabilization system Rru_A0699 11 COG3668 ParE, Plasmid stabilization system protein General function prediction only 83594827 Common - Ubiquinone biosynthesis protein COQ7 Rru_A3498 34 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 83592741 Common - MCP methyltransferase, CheR-type Rru_A1405 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 83593376 Common - aminotransferase Rru_A2041 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 83591802 Common - Aldehyde dehydrogenase Rru_A0462 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83593645 Common - cytochrome c family protein Rru_A2310 22 None None None 83594351 Common - hypothetical protein Rru_A3021 7 None None None 83591710 Common - Protein of unknown function DUF58 Rru_A0370 48 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 83593429 Common - Acriflavin resistance protein Rru_A2094 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 83592993 Common - acyl-CoA synthetase Rru_A1658 210 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83593557 Common - Molybdopterin biosynthesis protein Rru_A2222 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 83591952 Nonpathogen - Bacteriochlorophyll 4-vinyl reductase Rru_A0613 14 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 83593332 Common - carboxylesterase family protein Rru_A1997 74 COG0657 Aes, Esterase/lipase Lipid metabolism 83592969 Common - NADH dehydrogenase (quinone) Rru_A1634 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 83592208 Nonpathogen - hypothetical protein Rru_A0872 1 None None None 83593680 Common - Glycosyl transferase, group 1 Rru_A2345 34 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83593794 Common - Protein of unknown function DUF924 Rru_A2459 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 83594876 Common - hypothetical protein Rru_A3547 5 COG2158 COG2158, Uncharacterized protein containing a Zn-finger-like domain General function prediction only 83592960 Common - hypothetical protein Rru_A1625 10 COG4424 COG4424, Uncharacterized protein conserved in bacteria Function unknown 83594233 Common - Histidine triad (HIT) protein Rru_A2901 62 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 83593168 Common - 3-hydroxyisobutyrate dehydrogenase Rru_A1833 156 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 83594211 Nonpathogen - hypothetical protein Rru_A2879 21 COG0392 COG0392, Predicted integral membrane protein Function unknown 83592018 Common - Transcriptional Regulator, TetR family Rru_A0679 33 COG1309 AcrR, Transcriptional regulator Transcription 83591923 Common - inner-membrane translocator Rru_A0584 86 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 83592415 Common - potassium/proton antiporter Rru_A1079 136 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 83592892 Common - NADH dehydrogenase subunit C Rru_A1557 169 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 83594192 Nonpathogen - hypothetical protein Rru_A2860 1 None None None 83594392 Common - Methylmalonyl-CoA mutase-like Rru_A3062 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 83592720 Common - sensory histidine kinase AtoS Rru_A1384 223 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 83594472 Common - Type III effector Hrp-dependent outers Rru_A3142 63 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 83592947 Common - Phosphoribosyl-AMP cyclohydrolase Rru_A1612 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 83591440 Common - hypothetical protein Rru_A0100 9 COG5439 COG5439, Uncharacterized conserved protein Function unknown 83594310 Common - Chlorophyllide reductase iron protein subunit X Rru_A2980 78 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 83591408 Common - Alpha/beta hydrolase fold Rru_A0068 84 COG2267 PldB, Lysophospholipase Lipid metabolism 83594018 Common rplW 50S ribosomal protein L23 Rru_A2686 219 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 83592204 Common - peptidase C14, caspase catalytic subunit p20 Rru_A0868 39 COG2319 COG2319, FOG: WD40 repeat General function prediction only 83594819 Common - Metallophosphoesterase Rru_A3490 82 COG1409 Icc, Predicted phosphohydrolases General function prediction only 83591553 Nonpathogen - hypothetical protein Rru_A0213 1 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 83593284 Nonpathogen - hypothetical protein Rru_A1949 1 None None None 83594537 Common - Protein of unknown function DUF423 Rru_A3207 17 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 83592514 Common - Anticodon-binding Rru_A1178 153 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83593155 Common - Thiamine-monophosphate kinase Rru_A1820 183 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 83594613 Common - Phasin Rru_A3283 15 COG5490 COG5490, Uncharacterized conserved protein Function unknown 83594075 Common - Radical SAM Rru_A2743 75 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 83592372 Common - Protein of unknown function DUF1045 Rru_A1036 27 None None None 83592607 Common - Metallophosphoesterase Rru_A1271 64 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 83594262 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Rru_A2930 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83592595 Common - hypothetical protein Rru_A1259 23 None None None 83594092 Nonpathogen - hypothetical protein Rru_A2760 1 None None None 83594950 Common - Methylated-DNA-(protein)-cysteine S-methyltransferase Rru_A3621 208 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 83593445 Common clpS ATP-dependent Clp protease adaptor protein ClpS Rru_A2110 118 COG2127 COG2127, Uncharacterized conserved protein Function unknown 83591415 Common - RNA-binding S4 Rru_A0075 66 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 83592689 Common - hypothetical protein Rru_A1353 34 COG3652 COG3652, Predicted outer membrane protein Function unknown 83593043 Nonpathogen - hypothetical protein Rru_A1708 4 None None None 83591443 Common - SlyX Rru_A0103 30 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 161777629 Common - preprotein translocase subunit SecA Rru_A0235 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 83592137 Common - 7-keto-8-aminopelargonate synthetase and related enzymes-like Rru_A0798 147 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 83593550 Common - Transcriptional Regulator, LysR family Rru_A2215 173 COG0583 LysR, Transcriptional regulator Transcription 83593842 Common - Orotate phosphoribosyl transferase Rru_A2507 125 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 83591383 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase, LpxD Rru_A0043 144 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 83592550 Common - Dihydrolipoamide succinyltransferase Rru_A1214 194 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 83593012 Common - Signal transduction histidine kinase, nitrogen specific, NtrB Rru_A1677 215 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 83591607 Common - Lytic transglycosylase, catalytic Rru_A0267 159 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 83591401 Common - Purine and other phosphorylases, family 1 Rru_A0061 18 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 83591615 Common - Alpha/beta hydrolase fold Rru_A0275 70 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 83593503 Common - Phosphoribosylglycinamide formyltransferase Rru_A2168 221 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 83593738 Common - Inositol phosphatase/fructose-1,6-bisphosphatase Rru_A2403 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 83592832 Common - Glycosyl transferase, group 1 Rru_A1496 69 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83592717 Common - Short chain fatty acid transporter Rru_A1381 39 COG2031 AtoE, Short chain fatty acids transporter Lipid metabolism 83592472 Common - Periplasmic binding protein Rru_A1136 72 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 83594845 Nonpathogen - hypothetical protein Rru_A3516 8 None None None 83591978 Common - Regulatory protein RecX Rru_A0639 15 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 83595040 Common - Thioredoxin-related Rru_A3711 212 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 83594027 Common rpoB DNA-directed RNA polymerase subunit beta Rru_A2695 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 83592562 Common - F0F1 ATP synthase subunit beta Rru_A1226 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 83591672 Common - Glutathione S-transferase-like Rru_A0332 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83592813 Nonpathogen - hypothetical protein Rru_A1477 4 None None None 83594165 Nonpathogen - hypothetical protein Rru_A2833 1 COG1360 MotB, Flagellar motor protein Cell motility and secretion 83591438 Common - Cystathionine gamma-synthase Rru_A0098 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 83592122 Nonpathogen - hypothetical protein Rru_A0783 2 None None None 83591645 Common - Hydrogenase expression/formation protein HypE Rru_A0305 153 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 83593851 Common - Multi-sensor Signal Transduction Histidine Kinase Rru_A2516 172 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83593933 Common - hypothetical protein Rru_A2601 61 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 83593751 Common - hypothetical protein Rru_A2416 11 None None None 83592617 Common - hypothetical protein Rru_A1281 9 None None None 83595116 Common - 2-nitropropane dioxygenase, NPD Rru_A3787 51 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 83592904 Common - Biotin--acetyl-CoA-carboxylase ligase Rru_A1569 151 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 83594884 Common - Heat shock protein Hsp70 Rru_A3555 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 83592180 Common - ABC transporter component Rru_A0844 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83593495 Common - Ppx/GppA phosphatase Rru_A2160 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 83591985 Common - Phosphoribosylamine--glycine ligase Rru_A0646 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 83592982 Common - hypothetical protein Rru_A1647 10 None None None 83592461 Nonpathogen - Transcriptional Regulator, XRE family Rru_A1125 5 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 83593591 Common - Cytochrome c, class II Rru_A2256 22 COG3909 COG3909, Cytochrome c556 Energy production and conversion 83593667 Common - Response regulator receiver domain protein (CheY) Rru_A2332 180 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83592053 Common - Protein of unknown function DUF1476 Rru_A0714 27 COG5467 COG5467, Uncharacterized conserved protein Function unknown 83593509 Common - Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like Rru_A2174 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 83594717 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase Rru_A3388 67 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 83591673 Common - Ferritin and Dps Rru_A0333 143 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 83592883 Common - Malonyl-CoA decarboxylase Rru_A1548 29 None None None 83592011 Nonpathogen - hypothetical protein Rru_A0672 2 None None None 83594583 Common - hypothetical protein Rru_A3253 10 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 83593670 Common - Transcriptional Regulator, AraC family Rru_A2335 71 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83592532 Common - aspartate-semialdehyde dehydrogenase Rru_A1196 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 83593863 Nonpathogen flgL flagellar hook-associated protein FlgL Rru_A2528 4 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 83593949 Common - Exonuclease VII, small subunit Rru_A2617 114 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 83591661 Common - NADH dehydrogenase (ubiquinone), 20 kDa subunit Rru_A0321 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 83591705 Common - tRNA/rRNA methyltransferase (SpoU) Rru_A0365 168 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 83591806 Common - tRNA isopentenyltransferase Rru_A0466 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 83592467 Common - Aminotransferase, class IV Rru_A1131 137 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 83592548 Common - succinyl-CoA synthetase subunit alpha Rru_A1212 206 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 83592225 Common - hypothetical protein Rru_A0889 4 None None None 83592257 Common - DNA-binding protein Rru_A0921 37 COG2944 COG2944, Predicted transcriptional regulator Transcription 83593224 Common - Triosephosphate isomerase Rru_A1889 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 83594226 Common - ABC transporter component Rru_A2894 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 83594173 Nonpathogen - Flagellar basal body-associated protein FliL Rru_A2841 9 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 83592247 Nonpathogen - hypothetical protein Rru_A0911 3 None None None 83591349 Common - PTS IIA-like nitrogen-regulatory protein PtsN Rru_A0009 140 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 83593529 Common - MaoC-like dehydratase Rru_A2194 68 COG2030 MaoC, Acyl dehydratase Lipid metabolism 83591860 Common - CheA Signal Transduction Histidine Kinases (STHK) Rru_A0521 205 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 83594588 Common - Ribonucleotide reductase large subunit Rru_A3258 220 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 83591530 Common - TonB-dependent receptor Rru_A0190 109 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 83595090 Common - hypothetical protein Rru_A3761 125 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 83592078 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Rru_A0739 200 COG0388 COG0388, Predicted amidohydrolase General function prediction only 83594651 Common - Transcriptional Regulator, Crp/Fnr family Rru_A3322 151 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83591342 Common - DNA polymerase III subunit beta Rru_A0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 83593630 Common - malto-oligosyltrehalose trehalohydrolase Rru_A2295 154 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 83593952 Common - Hemolysin A Rru_A2620 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 83594543 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Rru_A3213 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 83593359 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Rru_A2024 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 83593381 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2046 195 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 83595097 Common - hypothetical protein Rru_A3768 77 COG3176 COG3176, Putative hemolysin General function prediction only 83594785 Common - hypothetical protein Rru_A3456 88 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 83591537 Nonpathogen - hypothetical protein Rru_A0197 3 None None None 83592629 Common - chemotaxis sensory transducer Rru_A1293 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83594053 Common - 2-oxoglutarate synthase, alpha subunit Rru_A2721 110 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 83594323 Common - hypothetical protein Rru_A2993 7 None None None 83591936 Common - Protein of unknown function DUF1526 Rru_A0597 23 None None None 83595012 Common - YceI Rru_A3683 76 COG2353 COG2353, Uncharacterized conserved protein Function unknown 83593720 Common - Substrate-binding region of ABC-type glycine betaine transport system Rru_A2385 86 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 83594777 Common - hypothetical protein Rru_A3448 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 83594985 Common - Polysaccharide biosynthesis protein CapD Rru_A3656 140 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83592002 Common - Cold-shock DNA-binding domain protein Rru_A0663 125 COG1278 CspC, Cold shock proteins Transcription 83594902 Common - Protein of unknown function DUF589 Rru_A3573 93 COG2947 COG2947, Uncharacterized conserved protein Function unknown 83593244 Nonpathogen - hypothetical protein Rru_A1909 1 None None None 83594590 Nonpathogen - hypothetical protein Rru_A3260 5 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 83592107 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0768 173 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 83594553 Common - ABC transporter component Rru_A3223 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 83592612 Common - anaerobic ribonucleoside triphosphate reductase Rru_A1276 125 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 83593732 Common - Sigma-24 (FecI) Rru_A2397 88 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83593366 Common anmK anhydro-N-acetylmuramic acid kinase Rru_A2031 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 83594923 Common - Histidine biosynthesis protein HisF Rru_A3594 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 83594744 Common - inner-membrane translocator Rru_A3415 150 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 83592214 Common - ABC transporter component Rru_A0878 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 83595001 Nonpathogen - hypothetical protein Rru_A3672 1 None None None 83594762 Common - Thioredoxin Rru_A3433 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 83592390 Common - hypothetical protein Rru_A1054 11 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 83593036 Common - Methionyl-tRNA synthetase, class Ia Rru_A1701 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83594728 Common - Transcriptional Regulator, BadM/Rrf2 family Rru_A3399 167 COG1959 COG1959, Predicted transcriptional regulator Transcription 83592303 Common - Carbon-monoxide dehydrogenase Rru_A0967 70 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 83594006 Common rpsH 30S ribosomal protein S8 Rru_A2674 246 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 83594743 Common - ABC transporter component Rru_A3414 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83593147 Common - Protein of unknown function DUF62 Rru_A1812 69 COG1912 COG1912, Uncharacterized conserved protein Function unknown 83593623 Common - DNA polymerase, beta-like region Rru_A2288 32 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 83594166 Nonpathogen - hypothetical protein Rru_A2834 1 None None None 83594709 Common - hypothetical protein Rru_A3380 39 COG2930 COG2930, Uncharacterized conserved protein Function unknown 83594158 Common - Flagellar basal-body rod protein FlgB Rru_A2826 68 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 83593762 Common - LrgB-like protein Rru_A2427 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 83593832 Common - Peptide chain release factor 3 Rru_A2497 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 83591783 Nonpathogen - hypothetical protein Rru_A0443 5 COG1432 COG1432, Uncharacterized conserved protein Function unknown 83591793 Common - HNH endonuclease Rru_A0453 16 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 83593140 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Rru_A1805 185 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 83594869 Common - hypothetical protein Rru_A3540 14 COG5642 COG5642, Uncharacterized conserved protein Function unknown 83592958 Nonpathogen - Amino acid-binding ACT Rru_A1623 5 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 83593027 Common - S-adenosylmethionine decarboxylase related Rru_A1692 72 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 83595037 Common - hypothetical protein Rru_A3708 17 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 83594295 Common - Riboflavin kinase / FAD synthetase Rru_A2965 211 COG0196 RibF, FAD synthase Coenzyme metabolism 83592234 Common - ATP/GTP-binding protein Rru_A0898 28 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 83594891 Nonpathogen - hypothetical protein Rru_A3562 2 None None None 83591835 Nonpathogen - hypothetical protein Rru_A0495 1 None None None 83592556 Common xerC site-specific tyrosine recombinase XerC Rru_A1220 222 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 83592567 Common - Protein of unknown function DUF610, YibQ Rru_A1231 34 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 83594781 Common - TonB-dependent receptor Rru_A3452 77 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 83593134 Common - Protein-L-isoaspartate(D-aspartate) O-methyltransferase Rru_A1799 157 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 83591458 Common - type II secretion system protein E Rru_A0118 155 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 83591632 Common - Integration host factor, beta subunit Rru_A0292 211 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 83592364 Nonpathogen - hypothetical protein Rru_A1028 2 None None None 83594938 Common - FxsA cytoplasmic membrane protein Rru_A3609 71 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 83592643 Common - Thioesterase superfamily Rru_A1307 21 COG0824 FcbC, Predicted thioesterase General function prediction only 83592425 Common ruvB Holliday junction DNA helicase B Rru_A1089 228 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 83591516 Common - Aminotransferase class-III Rru_A0176 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 83591933 Common - putative sulfite oxidase subunit YedZ Rru_A0594 73 COG2717 COG2717, Predicted membrane protein Function unknown 83594765 Common - Nucleotidyl transferase Rru_A3436 204 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 83593002 Common - Beta-ketoacyl-acyl carrier protein synthase III (FabH) Rru_A1667 207 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 83593404 Common - hypothetical protein Rru_A2069 19 None None None 83592672 Common - Periplasmic binding protein/LacI transcriptional regulator Rru_A1336 81 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 83592804 Common - bifunctional enoyl-CoA hydratase/phosphate acetyltransferase Rru_A1468 157 COG0280 Pta, Phosphotransacetylase Energy production and conversion 83594700 Common - Zinc-containing alcohol dehydrogenase superfamily Rru_A3371 181 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 83591351 Common - ABC transporter component Rru_A0011 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 83591354 Common - KpsF/GutQ Rru_A0014 143 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 83594002 Common rpmD 50S ribosomal protein L30 Rru_A2670 148 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 83594145 Common - Molybdopterin cofactor biosynthesis MoaC region Rru_A2813 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 83594996 Common - Short-chain dehydrogenase/reductase SDR Rru_A3667 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 83592639 Common - imidazolonepropionase Rru_A1303 98 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 83594517 Common - Two component Transcriptional regulator, Winged helix family Rru_A3187 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83593727 Common - hypothetical protein Rru_A2392 11 None None None 83595022 Common - hypothetical protein Rru_A3693 211 COG0313 COG0313, Predicted methyltransferases General function prediction only 83594379 Common - glycine dehydrogenase subunit 1 Rru_A3049 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 83594276 Common - ArgK protein Rru_A2944 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 83594150 Common alaS alanyl-tRNA synthetase Rru_A2818 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83592587 Nonpathogen - hypothetical protein Rru_A1251 1 None None None 83592543 Common - exopolyphosphatase-related protein Rru_A1207 11 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 83592447 Common - Pseudouridine synthase, RluD Rru_A1111 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 83592682 Common - Pentulose kinase Rru_A1346 143 COG1069 AraB, Ribulose kinase Energy production and conversion 83594434 Common - Two Component, Sigma54 Specific, Transcriptional Regulator, Fis family Rru_A3104 178 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83595061 Nonpathogen - hypothetical protein Rru_A3732 2 None None None 83593192 Common - RNA polymerase, omega subunit Rru_A1857 111 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 83592116 Common - D-lactate dehydrogenase (cytochrome) Rru_A0777 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 83592031 Common - Response regulator receiver domain protein (CheY) Rru_A0692 123 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 83594660 Common - Cytochrome C oxidase, mono-heme subunit/FixO Rru_A3331 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 83593502 Common - Phosphoribosylformylglycinamidine cyclo-ligase Rru_A2167 229 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 83593698 Common - Endonuclease/exonuclease/phosphatase Rru_A2363 73 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 83594608 Common - ADP-L-glycero-D-manno-heptose-6-epimerase Rru_A3278 221 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 83591453 Common - type II secretion system protein E Rru_A0113 194 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 83592240 Common - Iron-containing alcohol dehydrogenase Rru_A0904 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 83591964 Nonpathogen - hypothetical protein Rru_A0625 3 None None None 83595122 Common - molybdopterin biosynthesis protein Rru_A3793 213 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 83592029 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Rru_A0690 212 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 83594723 Nonpathogen - hypothetical protein Rru_A3394 1 None None None 83591601 Common - hypothetical protein Rru_A0261 17 None None None 83591827 Common - Alpha/beta hydrolase fold Rru_A0487 82 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 83591878 Common flhA flagellar biosynthesis protein A Rru_A0539 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 83594328 Common - Acetate kinase Rru_A2998 162 COG0282 ackA, Acetate kinase Energy production and conversion 83593991 Common - Pseudouridine synthase, RluD Rru_A2659 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 83593435 Common - Protein of unknown function DUF81 Rru_A2100 140 COG0730 COG0730, Predicted permeases General function prediction only 83595030 Common - Transcriptional Regulator, TetR family Rru_A3701 56 COG1309 AcrR, Transcriptional regulator Transcription 83592097 Common - Transcriptional Regulator, AraC family Rru_A0758 105 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83592100 Common - Radical SAM Rru_A0761 30 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 83593884 Common - HAD-superfamily hydrolase subfamily IIB Rru_A2549 68 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 83593753 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2418 207 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 83592912 Common - ThiJ/PfpI Rru_A1577 65 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 83593876 Common - hypothetical protein Rru_A2541 49 COG5483 COG5483, Uncharacterized conserved protein Function unknown 83591499 Common - Exodeoxyribonuclease VII Rru_A0159 196 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 83592266 Common - Iron-containing alcohol dehydrogenase Rru_A0930 175 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 83594863 Common - hypothetical protein Rru_A3534 11 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 83593769 Common - Acetyl-CoA biotin carboxyl carrier Rru_A2434 177 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 83592972 Common - putative monovalent cation/H+ antiporter subunit B Rru_A1637 24 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 83594890 Common - ABC transporter, transmembrane region Rru_A3561 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 83594811 Common - Transcriptional Regulator, MarR family Rru_A3482 81 COG1846 MarR, Transcriptional regulators Transcription 83591397 Common - hypothetical protein Rru_A0057 32 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 83592712 Common - hypothetical protein Rru_A1376 2 None None None 83593729 Common - PepSY-associated TM helix Rru_A2394 29 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 83592838 Nonpathogen - hypothetical protein Rru_A1502 1 None None None 83593778 Common - HipA protein Rru_A2443 64 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 83594504 Common - Major facilitator superfamily MFS_1 Rru_A3174 34 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83592505 Common - Hydrogenase accessory protein HypB Rru_A1169 143 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 83591413 Common - ribosomal subunit interface protein, putative Rru_A0073 20 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 83592311 Common - Prevent-host-death protein Rru_A0975 46 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 83592853 Nonpathogen - hypothetical protein Rru_A1518 1 None None None 83594783 Common - Binding-protein-dependent transport systems inner membrane component Rru_A3454 82 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 83592087 Common hisS histidyl-tRNA synthetase Rru_A0748 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 83591751 Common rplI 50S ribosomal protein L9 Rru_A0411 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 83594205 Common - Extracellular ligand-binding receptor Rru_A2873 143 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83593679 Nonpathogen - hypothetical protein Rru_A2344 3 None None None 83593977 Nonpathogen - hypothetical protein Rru_A2645 1 None None None 83591495 Common - Transcriptional Regulator, TetR family Rru_A0155 53 COG1309 AcrR, Transcriptional regulator Transcription 83591758 Common - 3-oxoacyl-(acyl carrier protein) synthase II Rru_A0418 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83592896 Common - NADH dehydrogenase subunit G Rru_A1561 194 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 83593519 Common - Pyridoxamine 5'-phosphate oxidase-related, FMN-binding Rru_A2184 47 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 83594022 Common - elongation factor Tu Rru_A2690 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 83593303 Common - Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Rru_A1968 15 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 83594702 Common - hypothetical protein Rru_A3373 33 None None None 83592934 Common - Lipid-A-disaccharide synthase Rru_A1599 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 83593256 Common - ABC transporter component Rru_A1921 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 83593815 Common - Methylmalonyl-CoA mutase Rru_A2480 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 83593702 Common - Response regulator receiver domain protein (CheY) Rru_A2367 83 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 83592980 Common - Protein of unknown function DUF192 Rru_A1645 88 COG1430 COG1430, Uncharacterized conserved protein Function unknown 83593512 Common - Binding-protein-dependent transport systems inner membrane component Rru_A2177 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83593656 Common - chemotaxis sensory transducer Rru_A2321 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83593909 Common - Glycogen debranching enzyme GlgX Rru_A2577 143 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 83595079 Nonpathogen - hypothetical protein Rru_A3750 4 None None None 83591567 Common - hypothetical protein Rru_A0227 28 COG5447 COG5447, Uncharacterized conserved protein Function unknown 83592751 Common - Protein of unknown function DUF132 Rru_A1415 16 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 83594788 Nonpathogen - hypothetical protein Rru_A3459 1 None None None 83591765 Nonpathogen - hypothetical protein Rru_A0425 1 None None None 83593416 Common - hypothetical protein Rru_A2081 2 None None None 83594481 Common - serine/threonine protein kinase Rru_A3151 8 None None None 83593743 Common - RecJ exonuclease Rru_A2408 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 83591885 Common - hypothetical protein Rru_A0546 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 83593968 Common - Cyclic nucleotide-binding domain (cNMP-BD) protein Rru_A2636 89 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 83594576 Common - F0F1 ATP synthase subunit A Rru_A3246 201 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 83593091 Nonpathogen - hypothetical protein Rru_A1756 2 None None None 83593146 Common - Beta-lactamase-like Rru_A1811 48 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 83594597 Common - Methionine biosynthesis MetW Rru_A3267 66 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 83594807 Common - Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain Rru_A3478 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 83593424 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Rru_A2089 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 83594411 Common - Protein of unknown function DUF891 Rru_A3081 41 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 83593363 Common - Transcriptional Regulator, BadM/Rrf2 family Rru_A2028 174 COG1959 COG1959, Predicted transcriptional regulator Transcription 83592166 Common - CRISPR-associated CT1133 family protein Rru_A0830 28 None None None 83592114 Common - 2OG-Fe(II) oxygenase Rru_A0775 54 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 83592660 Common - malonate decarboxylase subunit beta Rru_A1324 101 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 83592441 Common - tRNA synthetase, class II (G, H, P and S) Rru_A1105 179 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 83591547 Common - Cobalt chelatase, CobT subunit Rru_A0207 42 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 83594617 Common - Sigma-24 (FecI) Rru_A3287 109 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 83591653 Common - Aldehyde ferredoxin oxidoreductase Rru_A0313 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 83593059 Common - ThiJ/PfpI Rru_A1724 105 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 83594468 Common - hypothetical protein Rru_A3138 21 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 83592631 Common - extracellular solute-binding protein, family 3 Rru_A1295 159 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 83593154 Nonpathogen - hypothetical protein Rru_A1819 1 None None None 83594854 Nonpathogen - hypothetical protein Rru_A3525 4 None None None 83593383 Common - ABC transporter component Rru_A2048 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 83592796 Common - Asparagine synthase Rru_A1460 86 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83593249 Common - Cold-shock DNA-binding domain protein Rru_A1914 176 COG1278 CspC, Cold shock proteins Transcription 83593614 Common - ATP-binding region, ATPase-like Rru_A2279 8 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 83593552 Nonpathogen - hypothetical protein Rru_A2217 1 None None None 83593659 Common - PBS lyase HEAT-like repeat Rru_A2324 14 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 83591730 Nonpathogen - hypothetical protein Rru_A0390 6 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 83593824 Common - Catalase Rru_A2489 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 83593916 Nonpathogen - hypothetical protein Rru_A2584 1 None None None 83594564 Common - processing peptidase Rru_A3234 197 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 83592282 Common - Cell division protein FtsQ Rru_A0946 99 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 83592697 Common - Glycerone kinase Rru_A1361 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 83594333 Common - Transcriptional Regulator, GntR family Rru_A3003 109 COG1802 GntR, Transcriptional regulators Transcription 83593111 Common - Peptidase M50 Rru_A1776 81 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 83594335 Common - Rubredoxin-type Fe(Cys)4 protein Rru_A3005 52 COG1773 COG1773, Rubredoxin Energy production and conversion 83591893 Common - Rh-like protein/ammonium transporter Rru_A0554 199 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 83594561 Common - isoprenoid biosynthesis protein with amidotransferase-like domain Rru_A3231 38 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 83593781 Common - ABC transporter component Rru_A2446 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 83593709 Common - TonB-dependent siderophore receptor Rru_A2374 108 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 83594268 Common - dihydroorotase Rru_A2936 208 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 83592448 Nonpathogen - hypothetical protein Rru_A1112 1 None None None 83592096 Common - Isochorismatase hydrolase Rru_A0757 75 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 83594623 Common - two-component response regulator (NarL subfamily) Rru_A3293 6 None None None 83592478 Common glyA serine hydroxymethyltransferase Rru_A1142 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 83592507 Common - Transcriptional Regulator, BadM/Rrf2 family Rru_A1171 59 COG1959 COG1959, Predicted transcriptional regulator Transcription 83593877 Common - circadian clock protein KaiC Rru_A2542 119 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 83592197 Common - Transcriptional Regulator, MarR family Rru_A0861 65 COG1846 MarR, Transcriptional regulators Transcription 83594321 Common - Precorrin-8X methylmutase Rru_A2991 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 83594203 Common - Peptidase M20D, amidohydrolase Rru_A2871 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 83591714 Common - hypothetical protein Rru_A0374 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 83593398 Common - Transcriptional Regulator, GntR family Rru_A2063 123 COG1802 GntR, Transcriptional regulators Transcription 83591361 Common - Transcriptional Regulator, MarR family Rru_A0021 120 COG1846 MarR, Transcriptional regulators Transcription 83594413 Common - NADPH-dependent FMN reductase Rru_A3083 113 COG0431 COG0431, Predicted flavoprotein General function prediction only 83593970 Nonpathogen - hypothetical protein Rru_A2638 1 None None None 83594831 Nonpathogen - hypothetical protein Rru_A3502 4 None None None 83593198 Common - Glutathione peroxidase Rru_A1863 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 83593573 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Rru_A2238 54 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 83591488 Common - GTP-binding protein TypA Rru_A0148 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 83591871 Common - Cobyrinic acid a,c-diamide synthase Rru_A0532 185 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 83593101 Common - Protein of unknown function DUF815 Rru_A1766 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 83593326 Common - hypothetical protein Rru_A1991 9 COG4711 COG4711, Predicted membrane protein Function unknown 83591729 Common - Antibiotic biosynthesis monooxygenase Rru_A0389 36 COG1359 COG1359, Uncharacterized conserved protein Function unknown 83592016 Common - hypothetical protein Rru_A0677 9 None None None 83591608 Common - Molybdopterin binding domain Rru_A0268 117 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 83594756 Common - tryptophan synthase subunit beta Rru_A3427 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 83594054 Common - 2-oxoglutarate synthase, beta subunit Rru_A2722 108 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 83592396 Common - Transcriptional Regulator, LysR family Rru_A1060 134 COG0583 LysR, Transcriptional regulator Transcription 83591540 Common - Restriction endonuclease Rru_A0200 25 COG1715 Mrr, Restriction endonuclease Defense mechanisms 83593021 Nonpathogen - hypothetical protein Rru_A1686 1 None None None 83591360 Common - Glutathione peroxidase Rru_A0020 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 83593734 Common - hypothetical protein Rru_A2399 27 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 83592387 Common - Phosphoribosylaminoimidazole carboxylase, ATPase subunit Rru_A1051 190 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 161777625 Common - 2-isopropylmalate synthase Rru_A1461 210 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 83591402 Common - terpene synthase, squalene cyclase Rru_A0062 39 COG1657 SqhC, Squalene cyclase Lipid metabolism 83592708 Nonpathogen - hypothetical protein Rru_A1372 1 None None None 83593286 Common - Transcriptional Regulator, AraC family Rru_A1951 73 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 83592493 Common - Potassium-transporting ATPase Rru_A1157 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 83591846 Common - Alpha amylase, catalytic region Rru_A0507 78 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 83593860 Common - Peptidase U32 Rru_A2525 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 83593776 Common - ribonucleotide-diphosphate reductase subunit alpha Rru_A2441 167 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 83594374 Common - hypothetical protein Rru_A3044 10 COG3403 COG3403, Uncharacterized conserved protein Function unknown 83595054 Common - ABC transporter component Rru_A3725 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 83594615 Common - two-component response regulator Rru_A3285 82 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 83591585 Common - Ribosomal RNA methyltransferase RrmJ/FtsJ Rru_A0245 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 83592294 Common - methyltransferase Rru_A0958 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 83592945 Common - hypothetical protein Rru_A1610 33 COG4335 COG4335, DNA alkylation repair enzyme DNA replication, recombination, and repair 83591503 Common - Transcriptional Regulator, XRE family Rru_A0163 18 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 83592298 Common - GCN5-related N-acetyltransferase Rru_A0962 3 COG0456 RimI, Acetyltransferases General function prediction only 83592692 Common - Catalase Rru_A1356 125 COG0753 KatE, Catalase Inorganic ion transport and metabolism 83594736 Common - 6-phosphofructokinase Rru_A3407 154 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 83594689 Common - Electron transport protein SCO1/SenC Rru_A3360 102 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 83593279 Common - DSBA oxidoreductase Rru_A1944 58 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 83594344 Common - ABC transporter component Rru_A3014 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 83594672 Common - pyrimidine 5-nucleotidase Rru_A3343 50 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 83593077 Common - Peptidylprolyl isomerase Rru_A1742 194 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 83592231 Common - putative transcriptional regulator Rru_A0895 27 None None None 83594317 Common - hypothetical protein Rru_A2987 16 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 83593356 Common - Endonuclease/exonuclease/phosphatase Rru_A2021 40 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 83592246 Common - ethanolamine utilization protein eutJ Rru_A0910 25 COG4820 EutJ, Ethanolamine utilization protein, possible chaperonin Amino acid transport and metabolism 83593583 Nonpathogen - hypothetical protein Rru_A2248 2 None None None 83593565 Common - Glycosyl transferase, family 9 Rru_A2230 86 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 83594128 Common - Heavy metal translocatin P-type ATPase Rru_A2796 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 83592866 Common - 5-methyltetrahydrofolate--homocysteine methyltransferase Rru_A1531 174 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 83592049 Common - Phosphoribosylformylglycinamidine synthetase PurS Rru_A0710 118 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 83594492 Common - prephenate dehydratase Rru_A3162 212 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 83593908 Common - glycogen branching enzyme Rru_A2576 155 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 83591396 Common - Toluene tolerance Rru_A0056 29 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 83592590 Common - putative aminotransferase Rru_A1254 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 83592722 Common - DEAD/DEAH box helicase Rru_A1386 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 83591514 Common - hypothetical protein Rru_A0174 17 None None None 83591560 Nonpathogen - hypothetical protein Rru_A0220 6 None None None 83593471 Nonpathogen - hypothetical protein Rru_A2136 6 None None None 83593050 Common - Twin-arginine translocation pathway signal Rru_A1715 62 COG2391 COG2391, Predicted transporter component General function prediction only 83593688 Nonpathogen - Tetratricopeptide TPR_4 Rru_A2353 10 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 83594499 Common - ABC transporter component Rru_A3169 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 83592287 Common - Cell cycle protein Rru_A0951 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 83594111 Common - Plasmid maintenance system antidote protein Rru_A2779 56 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 83591597 Common - Protein of unknown function DUF898 Rru_A0257 35 COG4269 COG4269, Predicted membrane protein Function unknown 83593406 Common - Methylmalonate-semialdehyde dehydrogenase Rru_A2071 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 83592652 Common - AMP-dependent synthetase and ligase Rru_A1316 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 83593466 Common - hypothetical protein Rru_A2131 8 None None None 83591476 Common - Protein of unknown function DUF6, transmembrane Rru_A0136 52 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 83592451 Common - Transcriptional Regulator, XRE family Rru_A1115 41 None None None 83593208 Common - Protein of unknown function DUF6, transmembrane Rru_A1873 3 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 83593251 Nonpathogen - Ferredoxin Rru_A1916 11 COG0633 Fdx, Ferredoxin Energy production and conversion 83593232 Common - Indole-3-glycerol-phosphate synthase Rru_A1897 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 83591371 Common - Transcriptional Regulator, LysR family Rru_A0031 160 COG0583 LysR, Transcriptional regulator Transcription 83594453 Nonpathogen - esterase/lipase/thioesterase family active site Rru_A3123 6 COG2267 PldB, Lysophospholipase Lipid metabolism 83592184 Common - Major facilitator superfamily MFS_1 Rru_A0848 93 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 83593483 Common - N-acetylmuramoyl-L-alanine amidase Rru_A2148 178 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 83592669 Common - BioY protein Rru_A1333 11 COG1268 BioY, Uncharacterized conserved protein General function prediction only 83594437 Common - Glycosyl transferase, group 1 Rru_A3107 140 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83593226 Common - Anthranilate synthase component I Rru_A1891 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 83594473 Common - putative aldolase Rru_A3143 123 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 83592577 Common rpmA 50S ribosomal protein L27 Rru_A1241 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 83593838 Common - Hydroxypyruvate isomerase Rru_A2503 78 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 83592582 Common - hypothetical protein Rru_A1246 64 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 83594979 Common - Lipolytic enzyme, G-D-S-L Rru_A3650 105 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 83592252 Common - pyruvate-formate lyase-activating enzyme Rru_A0916 74 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 83593922 Common - hypothetical protein Rru_A2590 12 None None None 83594189 Common - Flagellar FlbT Rru_A2857 15 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 83593125 Common - ABC-2 transporter component Rru_A1790 150 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 83593456 Common - hypothetical protein Rru_A2121 11 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 83593016 Common trkA potassium transporter peripheral membrane component Rru_A1681 156 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 83592337 Common - ABC transporter component Rru_A1001 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 83592322 Nonpathogen - hypothetical protein Rru_A0986 1 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 83591955 Nonpathogen - photosynthetic complex assembly protein Rru_A0616 9 None None None 83592605 Common - transcription factor Rru_A1269 8 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 83593532 Common - 3,4-Dihydroxy-2-butanone 4-phosphate synthase Rru_A2197 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 83592418 Nonpathogen - hypothetical protein Rru_A1082 1 None None None 83595063 Common - Glutamyl-tRNA synthetase, class Ic Rru_A3734 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 83593110 Common - chromosome segregation and condensation protein ScpA Rru_A1775 134 COG1354 COG1354, Uncharacterized conserved protein Function unknown 83591856 Common ppnK inorganic polyphosphate/ATP-NAD kinase Rru_A0517 220 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 83593605 Common - Nitrogen-fixing NifU-like Rru_A2270 54 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 83592732 Common - chemotaxis sensory transducer Rru_A1396 83 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 83592212 Nonpathogen - hypothetical protein Rru_A0876 1 None None None 83593035 Common - TatD-related deoxyribonuclease Rru_A1700 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 83592067 Common - hypothetical protein Rru_A0728 17 None None None 83593626 Common - DNA/RNA non-specific endonuclease Rru_A2291 26 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 83592512 Common - Histone deacetylase superfamily Rru_A1176 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 83595072 Nonpathogen - hypothetical protein Rru_A3743 9 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 83595102 Common - CBS domain protein Rru_A3773 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 83592811 Common - Citrate transporter Rru_A1475 31 COG2851 CitM, H+/citrate symporter Energy production and conversion 83594366 Common - Helicase c2 Rru_A3036 116 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 83591791 Common - hypothetical protein Rru_A0451 20 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 83592174 Common - TonB-dependent receptor Rru_A0838 99 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 83592458 Common - Beta-lactamase-like Rru_A1122 121 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 83593697 Common - Protein-methionine-S-oxide reductase Rru_A2362 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 83592400 Common - Plasmid maintenance system killer Rru_A1064 58 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 83592784 Common - Arsenical resistance operon trans-acting repressor ArsD Rru_A1448 31 None None None 83592991 Common - hypothetical protein Rru_A1656 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 83591748 Common - Protein of unknown function DUF140 Rru_A0408 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 83592987 Common - Transcriptional Regulator, LysR family Rru_A1652 181 COG0583 LysR, Transcriptional regulator Transcription 83594394 Common - Isovaleryl-CoA dehydrogenase Rru_A3064 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 83591739 Common - Phosphoesterase, PA-phosphatase related Rru_A0399 60 None None None 83592925 Common - Di-trans-poly-cis-decaprenylcistransferase Rru_A1590 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 83593430 Common - Secretion protein HlyD Rru_A2095 166 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 83594041 Common - Thioesterase superfamily Rru_A2709 126 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 83592156 Common - Asparagine synthase Rru_A0819 136 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 83592524 Common rplS 50S ribosomal protein L19 Rru_A1188 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 83595109 Common - hypothetical protein Rru_A3780 39 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 83594606 Common - Ornithine carbamoyltransferase Rru_A3276 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 83592776 Common - TonB-dependent siderophore receptor Rru_A1440 95 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 83593989 Common - AsmA Rru_A2657 31 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 83594110 Common - Plasmid maintenance system killer Rru_A2778 29 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 83591626 Common - hypothetical protein Rru_A0286 6 COG4285 COG4285, Uncharacterized conserved protein Function unknown 83591788 Common - Protein of unknown function DUF52 Rru_A0448 67 COG1355 COG1355, Predicted dioxygenase General function prediction only 83592781 Common nrdF ribonucleotide-diphosphate reductase subunit beta Rru_A1445 150 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 83593607 Common - TspO and MBR related proteins Rru_A2272 65 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 83592140 Common - Binding-protein-dependent transport systems inner membrane component Rru_A0801 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 83593004 Common - Transcriptional Regulator, MerR family Rru_A1669 91 COG0789 SoxR, Predicted transcriptional regulators Transcription 83593046 Common - Endoribonuclease L-PSP Rru_A1711 67 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 83591994 Common - Transcriptional Regulator, AsnC family Rru_A0655 158 COG1522 Lrp, Transcriptional regulators Transcription 83591590 Common - Xylulokinase Rru_A0250 184 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 83593844 Common - fructose-bisphosphate aldolase Rru_A2509 75 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 83593014 Common - Multi-sensor Signal Transduction Histidine Kinase Rru_A1679 221 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 83593980 Common - FAD dependent oxidoreductase Rru_A2648 86 COG0579 COG0579, Predicted dehydrogenase General function prediction only