Chlorobium chlorochromatii CaD3, complete genome NC_007514 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 78189131 Common - penicillin-binding protein 2 Cag_1164 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 78188378 Common - Chlorophyllide reductase iron protein subunit X Cag_0400 72 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 78188664 Common - MoaA/NifB/PqqE family protein Cag_0688 47 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 78189914 Common - hypothetical protein Cag_1961 43 COG2210 COG2210, Uncharacterized conserved protein Function unknown 78188397 Common - Chromosome segregation protein SMC Cag_0419 193 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 78189305 Nonpathogen - hypothetical protein Cag_1340 1 None None None 78188567 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Cag_0589 241 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 78189229 Nonpathogen - hypothetical protein Cag_1263 2 None None None 78188572 Common - hypothetical protein Cag_0594 20 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 78188176 Common - mannose-1-phosphate guanylyltransferase, putative Cag_0193 217 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 78188643 Common - probable polysaccharide biosynthesis protein Cag_0665 67 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 78189750 Nonpathogen - hypothetical protein Cag_1794 1 None None None 78188068 Common - transcriptional regulator, XRE family Cag_0084 30 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 78188745 Common - Acetylglutamate kinase Cag_0774 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 78188159 Common - hypothetical protein Cag_0176 87 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 78188358 Common - DEAD/DEAH box helicase-like Cag_0380 71 COG4889 COG4889, Predicted helicase General function prediction only 78188450 Nonpathogen - hypothetical protein Cag_0472 1 None None None 78189164 Common - hypothetical protein Cag_1197 3 None None None 78188422 Common - inorganic pyrophosphatase Cag_0444 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 78188526 Common - DNA primase Cag_0548 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 78188628 Common - exopolysaccharide biosynthesis protein Cag_0650 39 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 78189265 Common - hypothetical protein Cag_1300 161 COG1959 COG1959, Predicted transcriptional regulator Transcription 78188457 Common - ATPase Cag_0479 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 78188890 Common - hypothetical protein Cag_0922 39 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 78188408 Common - hypothetical protein Cag_0430 5 None None None 78189500 Common - two component transcriptional regulator, winged helix family Cag_1540 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 78189191 Common - Uncharacterized low-complexity proteins-like Cag_1224 97 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 78188432 Common - phosphoglucomutase/phosphomannomutase family protein Cag_0454 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 78189856 Common - 3-isopropylmalate dehydrogenase Cag_1901 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 78189017 Nonpathogen - hypothetical protein Cag_1050 1 None None None 78189499 Common - PAS/PAC sensor signal transduction histidine kinase Cag_1539 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 78189254 Common - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Cag_1288 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 78188027 Common - hypothetical protein Cag_0043 157 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 78189279 Common - hypothetical protein Cag_1314 8 None None None 78188946 Common - ATPase, ParA family Cag_0978 193 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 78188084 Common - hypothetical protein Cag_0101 59 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 78189106 Common - Adenylosuccinate lyase Cag_1139 240 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 78189634 Nonpathogen - Ric1 protein Cag_1677 3 None None None 78189010 Common - hypothetical protein Cag_1043 27 None None None 78189474 Common - uroporphyrinogen-III synthase Cag_1514 73 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 78189412 Common - UDP-N-acetylglucosamine pyrophosphorylase Cag_1451 212 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 78189178 Nonpathogen - hypothetical protein Cag_1211 11 COG1833 COG1833, Uncharacterized conserved protein Function unknown 78188811 Common - TPR repeat Cag_0840 129 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 78188300 Common - hypothetical protein Cag_0322 15 None None None 78189340 Common - D-3-phosphoglycerate dehydrogenase Cag_1377 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 78188935 Common - superoxide dismutase Cag_0967 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 78189610 Common - NifU protein, putative Cag_1653 100 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 78188798 Common - Adenylate kinase, subfamily Cag_0827 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 78188258 Common - Sel1-like repeat Cag_0277 110 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 78189209 Common - hypothetical protein Cag_1243 17 COG5464 COG5464, Uncharacterized conserved protein Function unknown 78188575 Common - transposase Cag_0597 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188276 Nonpathogen - transcriptional regulator-like Cag_0295 16 COG2522 COG2522, Predicted transcriptional regulator General function prediction only 78189508 Common - S-adenosyl-L-homocysteine hydrolase Cag_1548 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 78188011 Common secF preprotein translocase subunit SecF Cag_0027 201 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 78188866 Common - methyltransferase, putative Cag_0896 58 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 78189237 Nonpathogen - Rhodanese-like Cag_1271 18 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 78189453 Common - iron-sulfur cluster-binding protein Cag_1492 44 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 78188505 Common - cell division protein, putative Cag_0527 93 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 78188390 Common - Putative molybdenum utilization protein ModD Cag_0412 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 78188738 Common - hypothetical protein Cag_0766 6 None None None 78188151 Common - hydrolase, isochorismatase family Cag_0168 93 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 78189775 Common - hypothetical protein Cag_1819 4 None None None 78188825 Common - hypothetical protein Cag_0855 12 None None None 78188042 Common - Cell division protein FtsA Cag_0058 179 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 78188212 Common - Magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase Cag_0229 107 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 78188845 Common - glutamine amidotransferase, class I Cag_0875 166 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 78188143 Common - TPR repeat Cag_0160 75 None None None 78188305 Common rpmE 50S ribosomal protein L31 Cag_0327 198 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 78189705 Common - DNA repair protein RecN Cag_1749 199 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 78189202 Nonpathogen - hypothetical protein Cag_1236 1 None None None 78189722 Common - peptide ABC transporter, permease protein Cag_1766 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 78189967 Common - F0F1 ATP synthase subunit beta Cag_2014 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 78188767 Common - citrate lyase, subunit 1 Cag_0796 204 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 78188004 Nonpathogen - hypothetical protein Cag_0020 2 None None None 78188817 Common - Helicase RecD/TraA Cag_0847 147 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 78188336 Common - DNA-directed RNA polymerase subunit beta' Cag_0358 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 78188114 Common - Phosphoheptose isomerase Cag_0131 121 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 78189328 Common - serine/threonine protein kinase Cag_1363 94 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 78188698 Common - HDIG Cag_0722 210 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 78188472 Common - Peptidase S1C, Do Cag_0494 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 78189372 Common - Membrane-fusion protein-like Cag_1409 137 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 78188330 Common - NusG antitermination factor Cag_0352 215 COG0250 NusG, Transcription antiterminator Transcription 78188683 Nonpathogen - hypothetical protein Cag_0707 9 None None None 78188401 Common - exopolyphosphatase, putative Cag_0423 182 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 78189154 Common - cytochrome c551 peroxidase Cag_1187 94 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 78188182 Common - glucokinase, putative Cag_0199 127 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 78188224 Common - extracellular solute-binding protein, family 3 Cag_0243 125 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 78189552 Common - hypothetical protein Cag_1592 51 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 78188920 Common - polysulfide reductase, subunit C, putative Cag_0952 22 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 78189358 Nonpathogen - anti-anti-sigma factor, putative Cag_1395 9 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 78189427 Common - hypothetical protein Cag_1466 20 None None None 78189664 Common - hypothetical protein Cag_1708 4 None None None 78188900 Common aspS aspartyl-tRNA synthetase Cag_0932 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78188838 Common - RND efflux system, outer membrane lipoprotein, NodT Cag_0868 99 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 78189733 Common - PIN (PilT N terminus) domain Cag_1777 57 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78189515 Common - Nitrogenase-associated protein Cag_1555 18 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 78189391 Common - Cobyrinic acid a,c-diamide synthase CbiA Cag_1429 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 78189870 Nonpathogen - hypothetical protein Cag_1917 1 None None None 78189082 Common - 3-deoxy-D-manno-octulosonic-acid transferase Cag_1115 126 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 78189292 Common - ATPase Cag_1327 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 78188429 Common - tryptophan synthase subunit beta Cag_0451 224 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 78188608 Common - hypothetical protein Cag_0630 13 None None None 78189332 Common - Heavy metal translocating P-type ATPase Cag_1369 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 78188219 Common - trigger factor Cag_0238 208 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 78188997 Nonpathogen - hydrogenase, methyl-violgen-reducing type, delta subunit Cag_1030 33 COG1908 FrhD, Coenzyme F420-reducing hydrogenase, delta subunit Energy production and conversion 78188777 Common - RfaE bifunctional protein, domain I Cag_0806 117 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 78189282 Common - DNA mismatch repair protein Cag_1317 200 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 78188371 Common - hydroxyneurosporene synthase CrtC Cag_0393 6 None None None 78188127 Common - ATPase Cag_0144 21 COG1106 COG1106, Predicted ATPases General function prediction only 78189073 Common - glycosyl transferase Cag_1106 195 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 78189188 Common - putative transcriptional regulator Cag_1221 65 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 78189087 Common - type I restriction-modification system specificity subunit Cag_1120 161 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 78189143 Common lysS lysyl-tRNA synthetase Cag_1176 246 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 78189513 Common - Sulphate anion transporter Cag_1553 162 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 78188205 Common - dihydroorotate dehydrogenase, electron transfer subunit Cag_0222 82 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 78188929 Common - Phosphoesterase, PA-phosphatase related Cag_0961 27 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 78189803 Common rpsS 30S ribosomal protein S19 Cag_1847 241 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 78189626 Common - 6-phosphogluconate dehydrogenase-like protein Cag_1669 191 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 78188316 Common - Succinyl-CoA synthetase, beta subunit Cag_0338 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 78189620 Common - Malonyl CoA-acyl carrier protein transacylase Cag_1663 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 78189544 Nonpathogen - heterodisulfide reductase, subunit A Cag_1584 35 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 78188875 Common - D-alanine--D-alanine ligase Cag_0905 215 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 78188659 Nonpathogen - transposase Cag_0682 19 None None None 78189793 Common rpsH 30S ribosomal protein S8 Cag_1837 216 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 78189026 Common - hypothetical protein Cag_1059 84 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78189674 Common - O-succinylbenzoate-CoA synthase Cag_1718 94 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 78188249 Nonpathogen - hypothetical protein Cag_0268 3 None None None 78189243 Nonpathogen - hypothetical protein Cag_1277 2 None None None 78189826 Common obgE GTPase ObgE Cag_1871 249 COG0536 Obg, Predicted GTPase General function prediction only 78189933 Common - peroxiredoxin Cag_1980 207 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 78189904 Common - DsrF protein Cag_1951 38 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 78189159 Common - transketolase-like Cag_1192 230 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 78189124 Common - peptide ABC transporter, permease protein, putative Cag_1157 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 78189609 Common - ATP-binding protein, Mrp/Nbp35 family Cag_1652 235 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 78189713 Common - Mg chelatase-related protein Cag_1757 193 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 78189438 Common - glycosyl transferase Cag_1477 27 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78189431 Common - phosphatidate cytidylyltransferase Cag_1470 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 78189724 Common - TPR repeat Cag_1768 64 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 78189111 Common - hypothetical protein Cag_1144 35 COG3809 COG3809, Uncharacterized protein conserved in bacteria Function unknown 78188545 Nonpathogen - hypothetical protein Cag_0567 3 None None None 78188009 Common mscL large-conductance mechanosensitive channel Cag_0025 111 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 78188639 Nonpathogen - hypothetical protein Cag_0661 1 None None None 78188536 Common - Secretion protein HlyD Cag_0558 154 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 78189689 Common - glycine dehydrogenase subunit 1 Cag_1733 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 78189969 Common - muramoyltetrapeptide carboxypeptidase, putative Cag_2016 80 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 78189860 Common - Acetolactate synthase, large subunit, biosynthetic type Cag_1905 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 78188333 Common rplJ 50S ribosomal protein L10 Cag_0355 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 78188586 Nonpathogen - hypothetical protein Cag_0608 1 None None None 78189039 Common - sialic acid synthase Cag_1072 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 78189071 Common - hypothetical protein Cag_1104 7 None None None 78189592 Common - CBS Cag_1634 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 78189656 Common - Menaquinone biosynthesis protein Cag_1700 137 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 78189948 Common - hypothetical protein Cag_1995 6 None None None 78189310 Common - Quinate/Shikimate 5-dehydrogenase Cag_1345 220 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 78189925 Common - glycosyl hydrolase, family 3 Cag_1972 179 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 78188529 Nonpathogen - hypothetical protein Cag_0551 3 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 78189795 Common rplE 50S ribosomal protein L5 Cag_1839 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 78188468 Common - GTP-binding protein LepA Cag_0490 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 78188282 Common - TPR repeat Cag_0301 195 COG1912 COG1912, Uncharacterized conserved protein Function unknown 78189573 Common - hypothetical protein Cag_1615 7 None None None 78189661 Common - Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like Cag_1705 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 78188135 Nonpathogen - hypothetical protein Cag_0152 5 None None None 78188020 Common - glycyl-tRNA synthetase Cag_0036 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 78188611 Nonpathogen - hypothetical protein Cag_0633 1 None None None 78188885 Common - cytochrome c-555 Cag_0917 39 COG3245 CycB, Cytochrome c5 Energy production and conversion 78188391 Common - Molybdenum ABC transporter, periplasmic binding protein Cag_0413 161 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 78189343 Common truA tRNA pseudouridine synthase A Cag_1380 230 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 78189424 Common nusA transcription elongation factor NusA Cag_1463 216 COG0195 NusA, Transcription elongation factor Transcription 78189398 Common - DedA family protein Cag_1436 9 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 78189952 Common - Ammonium transporter Cag_1999 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 78189956 Common - fic family protein Cag_2003 116 COG3177 COG3177, Uncharacterized conserved protein Function unknown 78188770 Common - oxidoreductase, FAD-binding Cag_0799 204 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 78189214 Common - Nitrogenase molybdenum-iron protein beta chain Cag_1248 55 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 78188831 Common - hypothetical protein Cag_0861 57 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 78189812 Common rpsL 30S ribosomal protein S12 Cag_1856 245 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 78189647 Nonpathogen - hypothetical protein Cag_1690 1 None None None 78188950 Common - Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like Cag_0982 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 78188685 Nonpathogen - hypothetical protein Cag_0709 1 None None None 78189877 Common - sulfur oxidation protein SoxZ Cag_1924 36 None None None 78188854 Common - Fibrobacter succinogenes major paralogous domain Cag_0884 5 None None None 78189016 Nonpathogen - hypothetical protein Cag_1049 3 None None None 78188265 Common - oxidoreductase, Gfo/Idh/MocA family Cag_0284 184 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 78188365 Common - RNA polymerase sigma factor rpoD (Sigma-A) Cag_0387 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 78189833 Common - alanine dehydrogenase Cag_1878 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 78189169 Nonpathogen - hypothetical protein Cag_1202 1 None None None 78188978 Common - L-threonine-O-3-phosphate decarboxylase Cag_1011 227 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 78188160 Common - hypothetical protein Cag_0177 9 None None None 78189064 Common - hypothetical protein Cag_1097 37 COG3177 COG3177, Uncharacterized conserved protein Function unknown 78189977 Common - phosphoribosylaminoimidazole synthetase Cag_2024 233 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 78188343 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta Cag_0365 116 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 78189005 Nonpathogen - hypothetical protein Cag_1038 3 None None None 78189897 Nonpathogen - polysulfide reductase, subunit C, putative Cag_1944 9 None None None 78188968 Nonpathogen - hypothetical protein Cag_1001 4 None None None 78189632 Common - ATPase Cag_1675 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 78189564 Common - hypothetical protein Cag_1604 9 None None None 78188713 Common - nucleotidyltransferase Cag_0737 14 None None None 78188108 Common - hydroxyacylglutathione hydrolase, putative Cag_0125 212 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 78189971 Common - hypothetical protein Cag_2018 113 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78189919 Common - hypothetical protein Cag_1966 14 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188782 Common - hypothetical protein Cag_0811 12 None None None 78189464 Nonpathogen - hypothetical protein Cag_1503 1 COG1933 COG1933, Archaeal DNA polymerase II, large subunit DNA replication, recombination, and repair 78188517 Common hisH imidazole glycerol phosphate synthase subunit HisH Cag_0539 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 78189534 Common - hypothetical protein Cag_1574 40 None None None 78188623 Common - hypothetical protein Cag_0645 5 None None None 78189129 Common smpB SsrA-binding protein Cag_1162 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 78188170 Common - Phosphoglycerate mutase 1 Cag_0187 162 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 78189892 Common - lysophospholipase L2, putative Cag_1939 64 COG1647 COG1647, Esterase/lipase General function prediction only 78188561 Nonpathogen - hypothetical protein Cag_0583 6 None None None 78188230 Common - acetyltransferase, CysE/LacA/LpxA/NodL family Cag_0249 200 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 78188313 Common - FusA/NodT family protein Cag_0335 101 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 78189193 Common - hypothetical protein Cag_1227 17 None None None 78188864 Common - hypothetical protein Cag_0894 69 COG1479 COG1479, Uncharacterized conserved protein Function unknown 78189757 Common - Divalent cation transporter Cag_1801 171 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 78188911 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase Cag_0943 109 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 78189497 Common - Elongator protein 3/MiaB/NifB Cag_1537 105 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 78188377 Common - Redox-active disulfide protein 2 Cag_0399 67 None None None 78188295 Common - Citrate synthase I Cag_0317 194 COG0372 GltA, Citrate synthase Energy production and conversion 78188593 Common - Outer membrane protein-like Cag_0615 86 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 78189547 Common - ATP-sulfurylase Cag_1587 64 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 78188520 Common - Pseudouridine synthase, Rsu Cag_0542 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 78188740 Common - Exodeoxyribonuclease V, beta subunit Cag_0769 221 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 78189769 Common chlL protochlorophyllide reductase iron-sulfur ATP-binding protein Cag_1813 85 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 78189487 Common - hypothetical protein Cag_1527 13 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 78189051 Common - ADP-L-glycero-D-manno-heptose-6-epimerase Cag_1084 225 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78188663 Common - hypothetical protein Cag_0686 13 COG5464 COG5464, Uncharacterized conserved protein Function unknown 78189679 Nonpathogen - hypothetical protein Cag_1723 1 None None None 78189784 Common rpmJ 50S ribosomal protein L36 Cag_1828 92 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 78189842 Common - von Willebrand factor, type A Cag_1887 55 None None None 78189033 Common - hypothetical protein Cag_1066 5 None None None 78189884 Common - Hit family protein Cag_1931 227 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 78189760 Common - ParB-like partition protein Cag_1804 182 COG1475 Spo0J, Predicted transcriptional regulators Transcription 78188075 Nonpathogen - hypothetical protein Cag_0092 3 None None None 78188466 Common - Formylmethionine deformylase Cag_0488 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 78188253 Nonpathogen - hypothetical protein Cag_0272 2 None None None 78188484 Common - glycosyl transferase Cag_0506 165 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 78189588 Common - hypothetical protein Cag_1630 6 None None None 78188193 Common - hypothetical protein Cag_0210 104 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 78189365 Common - DNA modification methylase-like Cag_1402 130 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 78188434 Nonpathogen rpsT 30S ribosomal protein S20 Cag_0456 6 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 78188721 Common - hypothetical protein Cag_0747 22 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 78188556 Common - hypothetical protein Cag_0578 50 COG4804 COG4804, Uncharacterized conserved protein Function unknown 78189069 Common - gamma-glutamyl phosphate reductase Cag_1102 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 78189690 Common dapA dihydrodipicolinate synthase Cag_1734 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 78189277 Common - hypothetical protein Cag_1312 20 COG2442 COG2442, Uncharacterized conserved protein Function unknown 78188992 Common - hypothetical protein Cag_1025 12 None None None 78187997 Nonpathogen - hypothetical protein Cag_0013 3 None None None 78189571 Common - putative ATPase involved in DNA repair Cag_1611 50 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 78188922 Common - Twin-arginine translocation pathway signal Cag_0954 175 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 78188441 Common - surface antigen family protein Cag_0463 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 78188297 Common - hypothetical protein Cag_0319 54 COG1872 COG1872, Uncharacterized conserved protein Function unknown 78188289 Common - hypothetical protein Cag_0310 10 None None None 78188302 Nonpathogen - Chlorophyllide reductase subunit Y Cag_0324 22 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 78189554 Nonpathogen - hypothetical protein Cag_1594 3 COG5373 COG5373, Predicted membrane protein Function unknown 78188674 Common - hypothetical protein Cag_0698 3 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 78188214 Common - Dihydroneopterin aldolase family Cag_0233 70 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 78188418 Common - two component transcriptional regulator, winged helix family Cag_0440 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 78188833 Common rpmA 50S ribosomal protein L27 Cag_0863 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 78188840 Common - ABC transporter, permease protein Cag_0870 24 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 78189303 Common - universal stress protein family Cag_1338 173 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 78188266 Common - coproporphyrinogen III oxidase Cag_0285 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 78189040 Common - Phosphatase kdsC Cag_1073 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 78188579 Nonpathogen - hypothetical protein Cag_0601 1 None None None 78189009 Common - hypothetical protein Cag_1042 28 COG4704 COG4704, Uncharacterized protein conserved in bacteria Function unknown 78188247 Common - Protein of unknown function DUF132 Cag_0266 14 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78188013 Common - DNA gyrase, B subunit Cag_0029 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 78188010 Common secD preprotein translocase subunit SecD Cag_0026 219 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 78188280 Common - hypothetical protein Cag_0299 45 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 78189472 Common - Filamentous haemagglutinin-like Cag_1512 99 None None None 78188024 Common - multidrug resistance protein A Cag_0040 126 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 162319770 Common rpsB 30S ribosomal protein S2 Cag_1648 230 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 78188274 Common - putative cytoplasmic protein Cag_0293 61 COG3943 COG3943, Virulence protein General function prediction only 78188318 Common - Glycosyltransferase probably involved in cell wall biogenesis-like Cag_0340 137 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 78189682 Common - hypothetical protein Cag_1726 65 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 78188692 Common - ATPase Cag_0716 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 78188657 Nonpathogen - hypothetical protein Cag_0680 1 None None None 78188899 Common - Elongator protein 3/MiaB/NifB Cag_0931 95 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 78189349 Common - transcriptional regulator, XRE family Cag_1386 12 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 78189219 Common - TonB-dependent receptor, putative Cag_1253 29 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 78189773 Common - GTPase EngB Cag_1817 190 COG0218 COG0218, Predicted GTPase General function prediction only 78188760 Common - periplasmic sensor hybrid histidine kinase Cag_0789 185 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 78189182 Nonpathogen - hypothetical protein Cag_1215 12 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 78189641 Common - Rare lipoprotein A Cag_1684 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 78189906 Nonpathogen - hypothetical protein Cag_1953 4 None None None 78188648 Common - hypothetical protein Cag_0670 3 None None None 78188847 Nonpathogen - hypothetical protein Cag_0877 2 None None None 78188568 Common - Penicillin-binding protein 1A Cag_0590 201 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 78188530 Common - TonB-like Cag_0552 28 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 78189334 Common - hypothetical protein Cag_1371 60 COG2836 COG2836, Uncharacterized conserved protein Function unknown 78189752 Common - Ankyrin Cag_1796 10 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 78188307 Common - GTPase EngC Cag_0329 163 COG1162 COG1162, Predicted GTPases General function prediction only 78188153 Common - hypothetical protein Cag_0170 38 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 78188057 Common - deoxyhypusine synthase-like protein Cag_0073 63 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 78188747 Common - arginine repressor Cag_0776 80 COG1438 ArgR, Arginine repressor Transcription 78188459 Common - Phosphoesterase PHP-like Cag_0481 138 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 78188116 Nonpathogen - hypothetical protein Cag_0133 1 None None None 78188474 Nonpathogen - hypothetical protein Cag_0496 3 None None None 78189149 Common - capsular polysaccharide biosynthesis protein I Cag_1182 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78189616 Common - Ribonuclease III Cag_1659 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 78188066 Common bioD dithiobiotin synthetase Cag_0082 112 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 78189880 Common - Twin-arginine translocation pathway signal Cag_1927 117 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 78189912 Common - redox protein regulator of disulfide bond formation-like Cag_1959 96 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 78189492 Common - hypothetical protein Cag_1532 10 None None None 78188452 Common - phosphoglucomutase/phosphomannomutase family protein Cag_0474 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 78188180 Common - hypothetical protein Cag_0197 15 None None None 78188229 Common - protoporphyrinogen oxidase, putative Cag_0248 8 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 78189098 Nonpathogen - hypothetical protein Cag_1131 2 None None None 78189162 Common - killer suppression protein HigA, putative Cag_1195 7 None None None 78188626 Common - Periplasmic protein involved in polysaccharide export-like Cag_0648 98 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 78188502 Common - transcriptional regulators, TraR/DksA family Cag_0524 99 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 78189502 Nonpathogen - hypothetical protein Cag_1542 3 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 78189168 Nonpathogen - hypothetical protein Cag_1201 1 None None None 78189137 Common - hypothetical protein Cag_1170 4 None None None 78188403 Common - putative transcriptional regulator, ArsR family Cag_0425 33 COG0640 ArsR, Predicted transcriptional regulators Transcription 78189526 Common - hydrogenase/sulfur reductase, beta subunit Cag_1566 31 None None None 78189735 Common - Branched-chain amino acid aminotransferase I Cag_1779 218 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 78189984 Common - Protein of unknown function DUF37 Cag_2031 188 COG0759 COG0759, Uncharacterized conserved protein Function unknown 78188688 Common - Queuine tRNA-ribosyltransferase Cag_0712 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 78189556 Common - hypothetical protein Cag_1596 61 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 78189299 Common pyrB aspartate carbamoyltransferase catalytic subunit Cag_1334 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 78189075 Common - 5,10-methylenetetrahydrofolate reductase Cag_1108 162 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 78189805 Common rplW 50S ribosomal protein L23 Cag_1849 201 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 78189511 Common - RNA-binding region RNP-1 (RNA recognition motif) Cag_1551 65 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 78188758 Common - Alkaline phosphatase Cag_0787 46 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 78189145 Nonpathogen - hypothetical protein Cag_1178 1 None None None 78189542 Common - heterodisulfide reductase, putative Cag_1582 49 COG1150 HdrC, Heterodisulfide reductase, subunit C Energy production and conversion 78189791 Common rplR 50S ribosomal protein L18 Cag_1835 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 78188203 Nonpathogen - chlorosome envelope protein C Cag_0220 3 None None None 78189024 Common - Cobalamin-5-phosphate synthase CobS Cag_1057 129 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 78188902 Common - ATPase Cag_0934 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 78188104 Common - hypothetical protein Cag_0121 62 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 78189235 Nonpathogen - hypothetical protein Cag_1269 3 COG5550 COG5550, Predicted aspartyl protease Posttranslational modification, protein turnover, chaperones 78188349 Common - putative ABC transporter, integral membrane protein Cag_0371 123 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 78188871 Common - Ribose/galactose isomerase Cag_0901 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 78188073 Common - CTP synthetase Cag_0090 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 78188873 Common - Peptidase M20D, amidohydrolase Cag_0903 171 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 78188144 Common - extragenic suppressor protein SuhB Cag_0161 211 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 78188641 Nonpathogen - hypothetical protein Cag_0663 2 None None None 78189961 Common - rubredoxin:oxygen oxidoreductase, putative Cag_2008 83 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 78188957 Common - ABC transporter efflux protein Cag_0989 184 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 78189741 Common - hypothetical protein Cag_1785 17 COG1409 Icc, Predicted phosphohydrolases General function prediction only 78188044 Common - 4-hydroxybutyrate coenzyme A transferase Cag_0060 101 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 78188089 Common - aminotransferase, class V Cag_0106 156 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 78189839 Common - hypothetical protein Cag_1884 3 None None None 78189407 Common - isoprenyl synthetase Cag_1446 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 78188981 Common - TonB-dependent receptor-related protein Cag_1014 129 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 78188933 Common - Dephospho-CoA kinase Cag_0965 174 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 78188509 Common - Hydrogenase expression/formation protein (HUPF/HYPC) Cag_0531 68 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 78188550 Common - translation-associated GTPase Cag_0572 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 78188769 Common - aspartate aminotransferase Cag_0798 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 78189700 Common rnhA ribonuclease H Cag_1744 174 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 78188244 Common - Alpha amylase, catalytic subdomain Cag_0263 16 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 78189241 Common - hypothetical protein Cag_1275 66 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 78189530 Common - virulence-associated protein D Cag_1570 6 COG3309 VapD, Uncharacterized virulence-associated protein D Function unknown 78188802 Common - regulatory proteins, AsnC family Cag_0831 106 COG3177 COG3177, Uncharacterized conserved protein Function unknown 78188670 Common - hypothetical protein Cag_0694 148 COG1610 COG1610, Uncharacterized conserved protein Function unknown 78188883 Common - transcriptional regulator, XRE family Cag_0914 13 COG1476 COG1476, Predicted transcriptional regulators Transcription 78189176 Common - peptidyl-prolyl cis-trans isomerase, PpiC-type Cag_1209 144 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 78189062 Common - SMR drug efflux transporter Cag_1095 116 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 78189251 Nonpathogen - hypothetical protein Cag_1285 1 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 78189707 Common - Prevent-host-death protein Cag_1751 42 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 78188494 Common - dTDP-glucose 4,6-dehydratase Cag_0516 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 78189767 Common - transcriptional regulator, XRE family Cag_1811 37 COG2944 COG2944, Predicted transcriptional regulator Transcription 78188823 Common - branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein, putative Cag_0853 142 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 78189896 Common - Siroheme synthase-like Cag_1943 124 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 78188603 Common - riboflavin synthase subunit alpha Cag_0625 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 78188819 Common - ATPase Cag_0849 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 78189205 Common - VCBS Cag_1239 119 None None None 78188681 Nonpathogen - hypothetical protein Cag_0705 3 None None None 78189672 Common - Chlorophyllide reductase subunit Z Cag_1716 27 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 78188795 Common - Dhh family protein Cag_0824 85 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 78189485 Common - type I restriction modification enzyme methylase subunit Cag_1525 149 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 78188821 Common - branched-chain amino acid ABC transporter, permease protein Cag_0851 80 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 78189290 Common - nucleic acid-binding protein,contains PIN domain Cag_1325 63 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78189824 Common - HPrNtr Cag_1869 149 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 78189089 Common - Restriction endonuclease S subunits-like Cag_1122 75 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 78188909 Common - CAAX prenyl protease 1, putative Cag_0941 62 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 78188362 Common - hypothetical protein Cag_0384 73 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78188709 Common - hypothetical protein Cag_0733 15 None None None 78188363 Nonpathogen - hypothetical protein Cag_0385 3 None None None 78188856 Common - hypothetical protein Cag_0886 42 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 78189931 Common - rubrerythrin Cag_1978 80 COG1592 COG1592, Rubrerythrin Energy production and conversion 78189594 Nonpathogen - hypothetical protein Cag_1637 4 None None None 78188169 Common - glutamate synthase, large subunit Cag_0186 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 78188137 Common - Excinuclease ABC, A subunit Cag_0154 242 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 78189561 Common - hypothetical protein Cag_1601 131 COG1678 COG1678, Putative transcriptional regulator Transcription 78189687 Common - RNA methyltransferase TrmH, group 3 Cag_1731 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 78188125 Common - Aspartate kinase region Cag_0142 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 78188094 Common - magnesium chelatase, subunit I, putative Cag_0111 180 COG0714 COG0714, MoxR-like ATPases General function prediction only 78188078 Common - Single-strand binding protein Cag_0095 203 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 78188380 Nonpathogen - 2-vinyl bacteriochlorophyllide hydratase Cag_0402 14 None None None 78188735 Common - hypothetical protein Cag_0762 12 COG5464 COG5464, Uncharacterized conserved protein Function unknown 78188971 Common - Protein of unknown function DUF196 Cag_1004 47 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 78189537 Common - hypothetical protein Cag_1577 13 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 78188772 Common rplS 50S ribosomal protein L19 Cag_0801 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 78188793 Common - hypothetical protein Cag_0822 4 None None None 78189003 Nonpathogen - uncharacterized conserved coiled coil protein Cag_1036 8 None None None 78188994 Common - aspartate aminotransferase Cag_1027 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 78188618 Common - NADH dehydrogenase I subunit 6 Cag_0640 43 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 78189613 Common - Glycine cleavage system T protein Cag_1656 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 78189950 Common - TPR repeat Cag_1997 54 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 78188254 Common - hypothetical protein Cag_0273 7 COG3668 ParE, Plasmid stabilization system protein General function prediction only 78189190 Common - methylmalonyl-CoA mutase Cag_1223 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 78189122 Common - Ribose-phosphate pyrophosphokinase Cag_1155 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 78189445 Common - ATPase Cag_1484 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 78188443 Common - Glutamyl-tRNA(Gln) amidotransferase A subunit Cag_0465 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 78189490 Nonpathogen - hypothetical protein Cag_1530 3 None None None 78189524 Common - membrane protein Cag_1564 12 COG0170 SEC59, Dolichol kinase Lipid metabolism 78189726 Nonpathogen - hypothetical protein Cag_1770 3 None None None 78188049 Common - ATP synthase F0, C subunit Cag_0065 14 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 78189920 Common - hypothetical protein Cag_1967 16 COG4694 COG4694, Uncharacterized protein conserved in bacteria Function unknown 78189366 Common metG methionyl-tRNA synthetase Cag_1403 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78189558 Common - hypothetical protein Cag_1598 9 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 78189528 Nonpathogen - hypothetical protein Cag_1568 1 None None None 78189035 Common - lipoyl synthase Cag_1068 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 78188222 Common recA recombinase A Cag_0241 223 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 78189297 Nonpathogen - hypothetical protein Cag_1332 3 None None None 78189432 Common - hypothetical protein Cag_1471 11 None None None 78189216 Common - nitrogenase iron-molybdenum cofactor biosynthesis protein NifN, putative Cag_1250 54 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 78189458 Nonpathogen - chlorobiumquinone synthase BchC related protein Cag_1497 13 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 78188194 Common hisG ATP phosphoribosyltransferase Cag_0211 214 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 78189849 Nonpathogen - photosystem P840 reaction center protein PscD Cag_1894 3 None None None 78188338 Common - Acetyl-CoA biotin carboxyl carrier Cag_0360 180 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 78188038 Common - cell division protein, FtsW/RodA/SpoVE family Cag_0054 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 78188179 Nonpathogen - hypothetical protein Cag_0196 3 None None None 78188712 Nonpathogen - hypothetical protein Cag_0736 1 None None None 78189830 Nonpathogen - TPR repeat Cag_1875 8 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 78189946 Common - ribonuclease HII Cag_1993 207 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 78189648 Common - serine esterase Cag_1691 100 COG0400 COG0400, Predicted esterase General function prediction only 78188676 Common - thiolredoxin peroxidase Cag_0700 228 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 78188050 Common - ATP synthase F0, subunit B Cag_0066 164 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 78189289 Common - hypothetical protein Cag_1324 19 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 78188232 Common - ATPase Cag_0251 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 78188235 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Cag_0254 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 78188961 Nonpathogen - hypothetical protein Cag_0993 1 None None None 78189840 Common - putative transcriptional regulator Cag_1885 73 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 78189352 Common - nucleic acid-binding protein,contains PIN domain Cag_1389 15 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78188661 Nonpathogen - hypothetical protein Cag_0684 2 None None None 78189782 Common - 30S ribosomal protein S11 Cag_1826 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 78189677 Common - hypothetical protein Cag_1721 12 None None None 78188944 Common - HAD-superfamily hydrolase subfamily IA Cag_0976 190 COG0546 Gph, Predicted phosphatases General function prediction only 78189361 Common - hypothetical protein Cag_1398 30 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 78188654 Common - teichuronic acid biosynthesis Cag_0676 114 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 78188387 Common - Phosphoserine phosphatase SerB Cag_0409 154 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 78188630 Common - GDP-mannose 4,6-dehydratase Cag_0652 225 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 78189189 Common - Methylmalonyl-CoA mutase N-terminal domain/subunit-like Cag_1222 107 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 78189104 Common - HhH-GPD Cag_1137 213 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 78188464 Common - TPR repeat Cag_0486 76 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 78188983 Common - hypothetical protein Cag_1016 61 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78188064 Common - hypothetical protein Cag_0080 12 COG2830 COG2830, Uncharacterized protein conserved in bacteria Function unknown 78189886 Common - succinate dehydrogenase/fumarate reductase iron-sulfur subunit Cag_1933 51 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 78188720 Nonpathogen - hypothetical protein Cag_0746 2 None None None 78188668 Common - hypothetical protein Cag_0692 13 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 78188584 Common - hypothetical protein Cag_0606 94 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 78189301 Common - hypothetical protein Cag_1336 28 COG5464 COG5464, Uncharacterized conserved protein Function unknown 78188321 Common - photosystem P840 reaction center, large subunit Cag_0343 10 None None None 78188436 Common - Folylpolyglutamate synthetase Cag_0458 214 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 78189422 Common - Ribosome-binding factor A Cag_1461 124 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 78189115 Common - hypothetical protein Cag_1148 14 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 78189067 Nonpathogen - hypothetical protein Cag_1100 3 None None None 78189323 Common - probable cb-type cytochrome c oxidase subunit III Cag_1358 57 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 78189284 Common - transcriptional modulator of MazE/toxin, MazF Cag_1319 41 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 78189814 Common - transcriptional regulator, XRE family Cag_1858 14 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 78188816 Common - cobalamin biosynthesis protein CobP Cag_0846 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 78189871 Common - transposase Cag_1918 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188029 Common - Aminodeoxychorismate lyase Cag_0045 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 78188005 Common - hypothetical protein Cag_0021 29 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 78189396 Nonpathogen - hypothetical protein Cag_1434 3 None None None 78189748 Common - hypothetical protein Cag_1792 17 None None None 78189084 Nonpathogen - hypothetical protein Cag_1117 3 None None None 78188704 Common - fructose-bisphosphate aldolase Cag_0728 178 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 78189058 Common - hypothetical protein Cag_1091 18 None None None 78188454 Nonpathogen - hypothetical protein Cag_0476 2 None None None 78188594 Common - Parallel beta-helix repeat Cag_0616 154 None None None 78188162 Common - DNA polymerase A Cag_0179 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 78188091 Common - YajC Cag_0108 86 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 78189970 Nonpathogen - hypothetical protein Cag_2017 4 COG2127 COG2127, Uncharacterized conserved protein Function unknown 78189314 Common - peptidyl-prolyl cis-trans isomerase, cyclophilin-type Cag_1349 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 78188486 Common - Rab family protein Cag_0508 9 COG1100 COG1100, GTPase SAR1 and related small G proteins General function prediction only 78189014 Common - hypothetical protein Cag_1047 29 None None None 78189585 Common - 3-oxoadipate enol-lactonase, putative Cag_1627 134 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 78188784 Common - Peptidase S41A, C-terminal protease Cag_0813 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 78189113 Common - hypothetical protein Cag_1146 25 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 78189975 Common - NLP/P60 family protein Cag_2022 121 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 78189127 Nonpathogen - pyruvoyl-dependent arginine decarboxylase Cag_1160 23 COG1945 COG1945, Uncharacterized conserved protein Function unknown 78188022 Common - hypothetical protein Cag_0038 14 COG5464 COG5464, Uncharacterized conserved protein Function unknown 78189470 Common - hypothetical protein Cag_1509 15 None None None 78189389 Nonpathogen - hypothetical protein Cag_1427 1 None None None 78188621 Common - Proton-translocating NADH-quinone oxidoreductase, chain M Cag_0643 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 78189462 Nonpathogen - hypothetical protein Cag_1501 3 None None None 78188563 Common - hypothetical protein Cag_0585 27 COG3668 ParE, Plasmid stabilization system protein General function prediction only 78189220 Nonpathogen - hypothetical protein Cag_1254 1 None None None 78188356 Common - helicase domain protein Cag_0378 31 COG4889 COG4889, Predicted helicase General function prediction only 78189658 Common - TPR repeat Cag_1702 127 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 78189091 Common - Type I site-specific deoxyribonuclease HsdR Cag_1124 135 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 78188913 Nonpathogen - hypothetical protein Cag_0945 3 None None None 78188515 Common - putative oxidoreductase Cag_0537 202 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 78189256 Common - Cell shape determining protein MreB/Mrl Cag_1290 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 78189532 Common - hypothetical protein Cag_1572 77 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78189890 Nonpathogen - hypothetical protein Cag_1937 3 None None None 78189759 Common - ATPase, ParA family Cag_1803 231 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 78188082 Common - sulfide dehydrogenase, flavoprotein subunit, putative Cag_0099 129 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 78188522 Common - hypothetical protein Cag_0544 8 None None None 78189456 Common - hypothetical protein Cag_1495 63 COG1950 COG1950, Predicted membrane protein Function unknown 78189650 Common - HRDC Cag_1694 10 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 78189000 Common - hydrogenase/sulfur reductase, gamma subunit Cag_1033 147 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 78188242 Nonpathogen - hypothetical protein Cag_0261 3 None None None 78188596 Common - Formate-dependent nitrite reductase membrane component-like Cag_0618 30 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 78189324 Common - Polyferredoxin-like Cag_1359 102 COG0348 NapH, Polyferredoxin Energy production and conversion 78189567 Common - Phosphoenolpyruvate-protein phosphotransferase Cag_1607 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 78188381 Common - hypothetical protein Cag_0403 49 COG4804 COG4804, Uncharacterized conserved protein Function unknown 78188348 Nonpathogen - ferredoxin, 4Fe-4S, putative Cag_0370 13 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 78188605 Common - outer membrane efflux protein, putative Cag_0627 142 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 78189701 Nonpathogen - hypothetical protein Cag_1745 3 None None None 78188227 Common - peptidyl-prolyl cis-trans isomerase, FKBP-type Cag_0246 162 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 78188588 Common - hypothetical protein Cag_0610 5 None None None 78188932 Common - Sec-independent periplasmic protein translocase Cag_0964 203 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 78189336 Common - hypothetical protein Cag_1373 6 None None None 78189669 Common rpmI 50S ribosomal protein L35 Cag_1713 124 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 78188046 Nonpathogen - hypothetical protein Cag_0062 3 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 78189799 Nonpathogen - 50S ribosomal protein L29 Cag_1843 4 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 78189238 Nonpathogen - hypothetical protein Cag_1272 1 None None None 78188702 Common - ABC transporter, periplasmic substrate-binding protein Cag_0726 163 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 78189232 Common - ThiS, thiamine-biosynthesis Cag_1266 14 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 78189754 Nonpathogen - transcriptional regulator, XRE family Cag_1798 2 COG1396 HipB, Predicted transcriptional regulators Transcription 78189244 Nonpathogen - hypothetical protein Cag_1278 1 None None None 78189523 Common secA preprotein translocase subunit SecA Cag_1563 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 162319775 Common - hypothetical protein Cag_0165 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 78188189 Common - IscS protein Cag_0206 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 78188878 Common - Prevent-host-death protein Cag_0908 5 None None None 78189822 Common - glycosyl transferase Cag_1867 143 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 78188778 Common - DNA-methyltransferase, type I restriction-modification enzyme subunit M Cag_0807 159 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 78189618 Common - Acyl carrier protein (ACP) Cag_1661 211 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 78188101 Nonpathogen - hypothetical protein Cag_0118 1 None None None 78189899 Nonpathogen - hypothetical protein Cag_1946 14 None None None 78189440 Common - Glycosyltransferase involved in cell wall biogenesis-like Cag_1479 194 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 78188455 Common - D-alanyl-D-alanine carboxypeptidease, putative Cag_0477 143 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 78189712 Common - hypothetical protein Cag_1756 34 COG2606 EbsC, Uncharacterized conserved protein Function unknown 78188986 Common - Phosphoribosylformylglycinamidine synthase II Cag_1019 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 78189459 Common - ATPase Cag_1498 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 78189222 Common - TPR repeat Cag_1256 173 COG2855 COG2855, Predicted membrane protein Function unknown 78189809 Common - elongation factor Tu Cag_1853 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 78189125 Nonpathogen - hypothetical protein Cag_1158 4 None None None 78188118 Common - hypothetical protein Cag_0135 4 None None None 78189699 Common rpmB 50S ribosomal protein L28 Cag_1743 144 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 78188375 Common - protein tyrosine phosphatase Cag_0397 140 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 78189907 Common - putative glutamate synthase (NADPH) small subunit Cag_1954 198 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 78189980 Common - putative phosphohistidine phosphatase, SixA Cag_2027 54 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 78188035 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase Cag_0051 201 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 78188924 Common - Prevent-host-death protein Cag_0956 30 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 78189376 Common - nitroreductase family protein Cag_1413 14 COG0778 NfnB, Nitroreductase Energy production and conversion 78188201 Nonpathogen - hypothetical protein Cag_0218 3 None None None 78188918 Common - K+-dependent Na+/Ca+ exchanger related-protein Cag_0950 130 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 78189478 Common - GTP-binding protein TypA Cag_1518 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 78189085 Common - Tyrosine recombinase XerD Cag_1118 229 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 78188820 Common - ATPase Cag_0850 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 78189807 Common rplC 50S ribosomal protein L3 Cag_1851 225 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 78189855 Common - 3-isopropylmalate dehydratase Cag_1900 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 78188842 Common - hypothetical protein Cag_0872 9 None None None 78189512 Nonpathogen - hypothetical protein Cag_1552 1 None None None 78188271 Common - hypothetical protein Cag_0290 141 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 78189727 Common - hypothetical protein Cag_1771 52 COG3762 COG3762, Predicted membrane protein Function unknown 78188959 Common - hypothetical protein Cag_0991 11 COG5464 COG5464, Uncharacterized conserved protein Function unknown 78188904 Common - MFS transporter family protein Cag_0936 85 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 78189737 Common - lipoprotein releasing system Cag_1781 179 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 78188388 Common - hypothetical protein Cag_0410 32 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 78189986 Common rpmH 50S ribosomal protein L34 Cag_2033 195 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 78189142 Common - phytoene desaturase Cag_1175 111 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 78188063 Common - 8-amino-7-oxononanoate synthase Cag_0079 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 78188172 Nonpathogen - hypothetical protein Cag_0189 3 None None None 78189070 Common - hypothetical protein Cag_1103 22 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 78188753 Common - ATP-dependent protease peptidase subunit Cag_0782 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 78188187 Common - Nucleoside diphosphate kinase Cag_0204 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 78188499 Common - hypothetical protein Cag_0521 10 COG5304 COG5304, Uncharacterized protein conserved in bacteria Function unknown 78189147 Common - hypothetical protein Cag_1180 20 None None None 78189779 Common rplQ 50S ribosomal protein L17 Cag_1823 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 78189296 Common - transcriptional regulator, Fis family Cag_1331 170 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 78189910 Common - sulfite reductase, dissimilatory-type, gamma subunit Cag_1957 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 78189174 Nonpathogen - hypothetical protein Cag_1207 3 None None None 78189253 Nonpathogen - hypothetical protein Cag_1287 1 None None None 78189101 Common - hypothetical protein Cag_1134 17 None None None 78189402 Common - aspartate aminotransferase, putative Cag_1440 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 78188741 Common - Exodeoxyribonuclease V, alpha subunit Cag_0770 118 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 78189770 Common - light-independent protochlorophyllide reductase subunit B Cag_1814 36 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 78188647 Common - sugar transferase Cag_0669 25 None None None 78188394 Common - Endonuclease III/Nth Cag_0416 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 78188800 Common - transcriptional modulator of MazE/toxin, MazF Cag_0829 23 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 78189685 Common - hypothetical protein Cag_1729 84 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78189309 Common - TPR repeat Cag_1344 159 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 78189138 Common - carbonic anhydrase family protein Cag_1171 142 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 78189680 Nonpathogen - hypothetical protein Cag_1724 3 None None None 78189642 Common - Acetate--CoA ligase Cag_1685 215 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 78189471 Nonpathogen - hypothetical protein Cag_1511 2 None None None 78189140 Common - hypothetical protein Cag_1173 46 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 78188849 Common pfkA 6-phosphofructokinase Cag_0879 157 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 78189765 Common - hypothetical protein Cag_1809 10 None None None 78189266 Common - Excinuclease ABC, A subunit Cag_1301 237 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 78189261 Common - hypothetical protein Cag_1296 17 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 78187990 Common - Orotidine 5'-phosphate decarboxylase subfamily 2 Cag_0006 74 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 78188423 Nonpathogen - hypothetical protein Cag_0445 2 None None None 78188155 Common - hypothetical protein Cag_0172 18 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 78188942 Common - PhoU Cag_0974 197 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 78188444 Common - Succinyl-CoA ligase, alpha subunit Cag_0466 210 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 78189841 Common - von Willebrand factor, type A Cag_1886 81 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 78188500 Nonpathogen - hypothetical protein Cag_0522 3 None None None 78189789 Common rpmD 50S ribosomal protein L30 Cag_1833 84 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 78188762 Common - Cell wall-associated hydrolase (invasion-associated proteins)-like Cag_0791 134 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 78188130 Common - rubredoxin Cag_0147 122 COG1773 COG1773, Rubredoxin Energy production and conversion 78188263 Common - Aspartate-semialdehyde dehydrogenase, USG-1 related Cag_0282 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 78189579 Common - Magnesium chelatase ATPase subunit I Cag_1621 71 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 78188686 Common - hypothetical protein Cag_0710 3 None None None 78188815 Common - transcriptional regulator, XRE family Cag_0845 18 COG2944 COG2944, Predicted transcriptional regulator Transcription 78188216 Common - Holo-acyl carrier protein synthase/Phosphopantethiene-protein transferase Cag_0235 155 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 78188477 Common - Phosphate transport system permease protein 2 Cag_0499 219 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 78189047 Common - hypothetical protein Cag_1080 12 None None None 78188492 Common - dTDP-4-dehydrorhamnose 3,5-epimerase related Cag_0514 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 78188030 Common - chorismate mutase, putative Cag_0046 41 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 78189258 Common - hypothetical protein Cag_1292 27 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 78189606 Common rpsI 30S ribosomal protein S9 Cag_1649 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 78189288 Nonpathogen - hypothetical protein Cag_1323 6 None None None 78187999 Common - hypothetical protein Cag_0015 35 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 78188015 Nonpathogen - hypothetical protein Cag_0031 2 None None None 78188835 Nonpathogen - hypothetical protein Cag_0865 2 None None None 78189815 Nonpathogen - hypothetical protein Cag_1860 3 None None None 78189888 Common - Succinate dehydrogenase, cytochrome b558 subunit Cag_1935 31 None None None 78189042 Common - carbon-nitrogen hydrolase family protein Cag_1075 186 COG0388 COG0388, Predicted amidohydrolase General function prediction only 78189165 Common - RND efflux system, outer membrane lipoprotein, NodT Cag_1198 127 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 78188691 Common - hypothetical protein Cag_0715 33 COG4185 COG4185, Uncharacterized protein conserved in bacteria Function unknown 78189013 Common - hypothetical protein Cag_1046 12 None None None 78189917 Common - molybdenum enzyme related to thiosulfate reductase and polysulfide reductase, large subunit Cag_1964 177 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 78188857 Common - hypothetical protein Cag_0887 30 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 78188481 Common - Acetylornithine and succinylornithine aminotransferase Cag_0503 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 78189158 Nonpathogen - hypothetical protein Cag_1191 1 None None None 78189837 Common - Transcription-repair coupling factor Cag_1882 220 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 78189893 Common - Rare lipoprotein A Cag_1940 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 78187985 Common - chromosomal replication initiator protein, DnaA Cag_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 78189218 Common - ferredoxin, 2Fe-2S Cag_1252 73 COG3411 COG3411, Ferredoxin Energy production and conversion 78188781 Common - DEAD/DEAH box helicase-like Cag_0810 125 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 78188475 Common - Triosephosphate isomerase Cag_0497 223 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 78189443 Common - ATPase Cag_1482 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 78188080 Common rplI 50S ribosomal protein L9 Cag_0097 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 78188571 Common - nucleotidyltransferase substrate-binding protein Cag_0593 30 None None None 78189093 Common - hypothetical protein Cag_1126 90 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 78189694 Nonpathogen - hypothetical protein Cag_1738 1 None None None 78189460 Common - membrane protein Cag_1499 106 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 78188324 Common - elongation factor G Cag_0346 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 78188196 Common - WD-40 repeat Cag_0213 70 COG2319 COG2319, FOG: WD40 repeat General function prediction only 78188207 Common - DNA polymerase III, delta subunit Cag_0224 31 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 78189118 Common - Thioredoxin reductase Cag_1151 248 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 78189383 Common - Glyceraldehyde-3-phosphate dehydrogenase, type I Cag_1420 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 78188138 Common - pyruvate phosphate dikinase Cag_0155 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 78188564 Common - hypothetical protein Cag_0586 45 COG0778 NfnB, Nitroreductase Energy production and conversion 78188553 Common - hypothetical protein Cag_0575 21 COG3668 ParE, Plasmid stabilization system protein General function prediction only 78189319 Common - nucleic acid-binding protein contains PIN domain-like Cag_1354 3 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78189401 Common - Coenzyme A biosynthesis protein Cag_1439 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 162319773 Common groES co-chaperonin GroES Cag_1305 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 78189354 Common - putative type II restriction enzyme Cag_1391 2 None None None 78188438 Common - electron transfer flavoprotein beta-subunit (beta-ETF) Cag_0460 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 78189941 Common - hypothetical protein Cag_1988 47 COG4198 COG4198, Uncharacterized conserved protein Function unknown 78189160 Common ksgA dimethyladenosine transferase Cag_1193 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 78189780 Common - DNA-directed RNA polymerase subunit alpha Cag_1824 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 78189504 Common - phenylalanyl-tRNA synthetase, beta subunit Cag_1544 247 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 78189535 Common - hypothetical protein Cag_1575 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 78189584 Nonpathogen - hypothetical protein Cag_1626 3 COG4980 GvpP, Gas vesicle protein General function prediction only 78188956 Common - ATPase Cag_0988 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 78188868 Common pyrC dihydroorotase Cag_0898 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 78188008 Common - hypothetical protein Cag_0024 11 COG1409 Icc, Predicted phosphohydrolases General function prediction only 78187986 Common - DNA polymerase III, beta chain Cag_0002 213 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 78188147 Common - Crossover junction endodeoxyribonuclease RuvC Cag_0164 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 78188023 Common - Drug resistance transporter EmrB/QacA subfamily Cag_0039 226 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 78189022 Common - Filamentous haemagglutinin-like Cag_1055 104 None None None 78189055 Common - hydrolase, alpha/beta hydrolase fold family Cag_1088 105 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 78188752 Common - Sigma-54 factor Cag_0781 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 78188237 Nonpathogen - hypothetical protein Cag_0256 2 None None None 78189817 Common - polysaccharide efflux transporter, putative Cag_1862 68 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 78188238 Common - ATPase Cag_0257 32 COG3950 COG3950, Predicted ATP-binding protein involved in virulence General function prediction only 78189596 Common - oxidoreductase, short-chain dehydrogenase/reductase family Cag_1639 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 78188488 Common - hypothetical protein Cag_0510 89 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 78188916 Nonpathogen - hypothetical protein Cag_0948 3 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 78189540 Common - transposase Cag_1580 58 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188888 Common - hypothetical protein Cag_0920 111 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 78189483 Common - DEAD/DEAH box helicase-like Cag_1523 115 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 78189030 Common - transposase Cag_1063 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188413 Common - two component transcriptional regulator, winged helix family Cag_0435 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 78188512 Common - Hydrogenase accessory protein HypB Cag_0534 153 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 78188786 Common - thiamine-phosphate pyrophosphorylase, putative Cag_0815 152 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 78189847 Common - heat shock protein, HSP20 family Cag_1892 160 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 78189197 Common - hypothetical protein Cag_1231 15 None None None 78189225 Nonpathogen - hypothetical protein Cag_1259 1 None None None 78188093 Nonpathogen - hypothetical protein Cag_0110 3 None None None 78188794 Common - aminopeptidase Cag_0823 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 78188964 Common - hypothetical protein Cag_0997 6 None None None 78188256 Common - NAD-dependent DNA ligase Cag_0275 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 78189421 Common - tRNA pseudouridine synthase B Cag_1460 239 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 78189184 Nonpathogen - hypothetical protein Cag_1217 3 None None None 78188040 Common - UDP-N-acetylmuramate--alanine ligase Cag_0056 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 78188341 Common - Acetyl-CoA carboxylase, alpha subunit Cag_0363 180 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 78189519 Common - transposase for IS1663 Cag_1559 102 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 78189437 Common - glycosyl transferase Cag_1476 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78189019 Common - hypothetical protein Cag_1052 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 78189600 Nonpathogen - hypothetical protein Cag_1643 3 None None None 78188809 Common - hypothetical protein Cag_0838 18 None None None 78188549 Common - cytidylate kinase Cag_0571 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 78188926 Common - hypothetical protein Cag_0958 7 None None None 78188060 Common - Cell wall hydrolase/autolysin Cag_0076 176 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 78189368 Nonpathogen - hypothetical protein Cag_1405 5 None None None 78189434 Common - hypothetical protein Cag_1473 230 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78189636 Common - hypothetical protein Cag_1679 19 None None None 78189012 Common - hypothetical protein Cag_1045 14 None None None 78189120 Common - hypothetical protein Cag_1153 5 COG4875 COG4875, Uncharacterized protein conserved in bacteria with a cystatin-like fold Function unknown 78189395 Common - possible NtrR protein Cag_1433 56 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78188583 Common - glycosyl transferase Cag_0605 223 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 78188625 Common - putative glycosyl transferase, family 4 Cag_0647 156 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 78188635 Common - putative transcriptional regulator Cag_0657 63 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 78189965 Common - phosphoenolpyruvate carboxykinase Cag_2012 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 78189945 Common - hypothetical protein Cag_1992 159 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 78188055 Common - Beta-phosphoglucomutase hydrolase Cag_0071 188 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 78188129 Common - Monofunctional biosynthetic peptidoglycan transglycosylase Cag_0146 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 78188542 Common - Histone-like DNA-binding protein Cag_0564 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 78188395 Common - NusB antitermination factor Cag_0417 171 COG0781 NusB, Transcription termination factor Transcription 78189569 Common - hypothetical protein Cag_1609 27 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 78189869 Common - hypothetical protein Cag_1916 15 None None None 78189921 Common - Glutamate-1-semialdehyde-2,1-aminomutase Cag_1968 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 78188382 Common - peptide ABC transporter, periplasmic peptide-binding protein, putative Cag_0404 189 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 78188533 Common - hypothetical protein Cag_0555 12 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 78189623 Common rpmF 50S ribosomal protein L32 Cag_1666 46 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 78188096 Common - hypothetical protein Cag_0113 5 None None None 78188368 Common thyX FAD-dependent thymidylate synthase Cag_0390 63 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 78188850 Common - hypothetical protein Cag_0880 10 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78189211 Common - nitrogen regulatory protein P-II (GlnB, GlnK) Cag_1245 181 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 78188311 Common - type II restriction endonuclease TdeIII Cag_0333 4 None None None 78189790 Common rpsE 30S ribosomal protein S5 Cag_1834 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 78189002 Nonpathogen - hypothetical protein Cag_1035 5 None None None 78189742 Nonpathogen - hypothetical protein Cag_1786 4 None None None 78189902 Nonpathogen - hypothetical protein Cag_1949 7 None None None 78188727 Common - cob(I)alamin adenosyltransferase Cag_0753 141 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 78188973 Common - Protein of unknown function DUF83 Cag_1006 55 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 78188361 Common - oxidoreductase, short-chain dehydrogenase/reductase family Cag_0383 95 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 78188164 Common - hypothetical protein Cag_0181 13 None None None 78188120 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase Cag_0137 203 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 78188616 Common - NADH dehydrogenase I chain H Cag_0638 191 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 78188898 Common - Phenylacetic acid degradation-related protein Cag_0930 90 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 78189928 Common - putative 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase Cag_1975 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 78189428 Common hisS histidyl-tRNA synthetase Cag_1467 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78189331 Nonpathogen - hypothetical protein Cag_1368 1 None None None 78189578 Common - Magnesium chelatase ATPase subunit D Cag_1620 69 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 78188775 Common rpsP 30S ribosomal protein S16 Cag_0804 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 78189864 Nonpathogen - hypothetical protein Cag_1909 4 None None None 78188269 Common - NADH dehydrogenase Cag_0288 200 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 78189873 Common - hypothetical protein Cag_1920 103 None None None 78188829 Common - oxaloacetate decarboxylase, alpha subunit Cag_0859 176 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 78188614 Common - NADH (or F420H2) dehydrogenase, subunit C Cag_0636 174 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 78188673 Common - hypothetical protein Cag_0697 38 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 78188427 Common - L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase Cag_0449 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 78189915 Nonpathogen - hypothetical protein Cag_1962 5 None None None 78189481 Common - methylmalonyl-CoA decarboxylase, alpha subunit Cag_1521 216 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 78188696 Common - hypothetical protein Cag_0720 17 COG1723 COG1723, Uncharacterized conserved protein Function unknown 78188724 Common - hypothetical protein Cag_0750 3 None None None 78189399 Common - transketolase-like Cag_1437 223 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 78188587 Common - hypothetical protein Cag_0609 23 COG1598 COG1598, Uncharacterized conserved protein Function unknown 78189829 Common - hypothetical protein Cag_1874 27 COG2930 COG2930, Uncharacterized conserved protein Function unknown 78188684 Common - transposase Cag_0708 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78189960 Common - DNA-directed DNA polymerase B Cag_2007 66 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 78188033 Common - Penicillin-binding protein 3 Cag_0049 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 78189517 Nonpathogen - hypothetical protein Cag_1557 14 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 78189144 Common - hypothetical protein Cag_1177 7 None None None 78189371 Common - Membrane-fusion protein-like Cag_1408 96 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 78189800 Common rplP 50S ribosomal protein L16 Cag_1844 217 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 78189853 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase Cag_1898 203 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 78189488 Nonpathogen - restriction modification system, type I Cag_1528 3 None None None 78189449 Common - hypothetical protein Cag_1488 61 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 78188273 Common - hypothetical protein Cag_0292 20 COG4365 COG4365, Uncharacterized protein conserved in bacteria Function unknown 78188755 Common - 3-dehydroquinate dehydratase Cag_0784 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 78189312 Common - TatD-related deoxyribonuclease Cag_1347 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 78188190 Common - IscU protein Cag_0207 125 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 78189510 Common - glutathione-regulated potassium-efflux system protein KefC, putative Cag_1550 193 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 78189357 Common - tRNA isopentenyltransferase Cag_1394 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 78189280 Common trpA tryptophan synthase subunit alpha Cag_1315 216 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 78188906 Common - Phosphoribosylformylglycinamidine synthetase PurS Cag_0938 101 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 78188185 Common - transposase Cag_0202 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188813 Common - hypothetical protein Cag_0843 25 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 78189739 Common - Dihydroorotate dehydrogenase 1 Cag_1783 220 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 78188827 Nonpathogen - hypothetical protein Cag_0857 3 None None None 78189909 Common - Sulfite reductase, dissimilatory-type alpha subunit Cag_1956 42 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 78189934 Common - transposase Cag_1981 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188805 Nonpathogen - hypothetical protein Cag_0834 1 None None None 78188497 Common - hypothetical protein Cag_0519 8 None None None 78189200 Common - universal stress protein family Cag_1234 177 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 78189746 Common - hypothetical protein Cag_1790 75 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 78189730 Common - LemA family protein Cag_1774 132 COG1704 LemA, Uncharacterized conserved protein Function unknown 78188996 Nonpathogen - heterodisulfide reductase, subunit A Cag_1029 37 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 78189338 Common - hypothetical protein Cag_1375 37 None None None 78188048 Common - H+-transporting two-sector ATPase, A subunit Cag_0064 184 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 78188554 Nonpathogen - hypothetical protein Cag_0576 5 None None None 78188590 Common - glucose-6-phosphate isomerase Cag_0612 199 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 78189576 Common - hypothetical protein Cag_1618 27 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 78189703 Common - phosphatidylserine decarboxylase Cag_1747 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 78188937 Nonpathogen - hypothetical protein Cag_0969 3 None None None 78188019 Common - Geranylgeranyl reductase Cag_0035 113 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 78189820 Nonpathogen - hypothetical protein Cag_1865 3 None None None 78189624 Nonpathogen - hypothetical protein Cag_1667 3 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 78188930 Common - hypothetical protein Cag_0962 48 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 78189077 Common rpmG 50S ribosomal protein L33 Cag_1110 20 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 78189457 Nonpathogen - Nuclear protein SET Cag_1496 8 COG2940 COG2940, Proteins containing SET domain General function prediction only 78189797 Common rplN 50S ribosomal protein L14 Cag_1841 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 78188411 Nonpathogen - pyruvoyl-dependent arginine decarboxylase Cag_0433 20 COG1945 COG1945, Uncharacterized conserved protein Function unknown 78189006 Common - Outer membrane protein and related peptidoglycan-associated (lipo)proteins-like Cag_1039 153 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 78189230 Common - trans-sulfuration enzyme family protein Cag_1264 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 78188098 Common - CrtF-related protein Cag_0115 52 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 78188708 Common - TPR repeat Cag_0732 125 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 78189697 Common - Anthranilate phosphoribosyl transferase Cag_1741 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 78189294 Nonpathogen - bacteriochlorophyll A protein Cag_1329 3 None None None 78189049 Common - ferredoxin, 4Fe-4S Cag_1082 97 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 78188791 Common - hypothetical protein Cag_0820 12 COG5464 COG5464, Uncharacterized conserved protein Function unknown 78188406 Common - transcriptional regulator/antitoxin, MazE Cag_0428 23 COG2336 MazE, Growth regulator Signal transduction mechanisms 78189720 Common - HPr kinase/phosphorylase Cag_1764 58 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 78188025 Common - outer membrane protein, putative Cag_0041 51 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 78188479 Common - periplasmic phosphate binding protein Cag_0501 133 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 78188299 Common xseA exodeoxyribonuclease VII large subunit Cag_0321 204 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 78188278 Common - hypothetical protein Cag_0297 122 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 78188506 Common - endonuclease IV Cag_0528 97 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 78188863 Common - DNA polymerase III, alpha subunit Cag_0893 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 78188012 Common - peptidyl-prolyl cis-trans isomerase SurA Cag_0028 160 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 78189109 Common - ATPase, E1-E2 type Cag_1142 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 78189834 Common - chlorosome envelope protein X Cag_1879 13 COG0633 Fdx, Ferredoxin Energy production and conversion 78188284 Common - peptidase, M16 family Cag_0303 166 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 78188017 Common - hypothetical protein Cag_0033 2 None None None 78189506 Common - glucose-1-phosphate thymidylyltransferase Cag_1546 237 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 78188061 Common - Biotin--acetyl-CoA-carboxylase ligase Cag_0077 228 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 78188693 Common - ATPase Cag_0717 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 78188678 Common - probable phage-related lysozyme Cag_0702 53 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 78188796 Common - hypothetical protein Cag_0825 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 78188303 Common - hypothetical protein Cag_0325 70 COG1479 COG1479, Uncharacterized conserved protein Function unknown 78188577 Common - hypothetical protein Cag_0599 5 None None None 78189548 Common - glutamine synthetase Cag_1588 65 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 78188053 Common - Probable nicotinate-nucleotide adenylyltransferase Cag_0069 175 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 78188327 Common - IspG protein Cag_0349 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 78188320 Common - Diaminopimelate epimerase Cag_0342 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 78188653 Common - putative glycosyl transferase Cag_0675 18 None None None 78188949 Common - hypothetical protein Cag_0981 64 COG3246 COG3246, Uncharacterized conserved protein Function unknown 78189268 Nonpathogen - hypothetical protein Cag_1303 5 None None None 78189136 Common - TPR repeat Cag_1169 101 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 78189756 Common - electron transfer flavoprotein-ubiquinone oxidoreductase Cag_1800 114 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 78189777 Common - mannose-1-phosphate guanylyltransferase, putative Cag_1821 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 78189072 Common - bacteriochlorophyll/chlorophyll a synthase Cag_1105 78 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 78188392 Common - Molybdate ABC transporter, permease protein Cag_0414 219 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 78188141 Common - CrtK protein Cag_0158 64 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 78188952 Common - hypothetical protein Cag_0984 11 None None None 78189133 Common - rod shape-determining protein MreC, putative Cag_1166 57 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 78189404 Common - hypothetical protein Cag_1443 13 None None None 78188157 Common - indole-3-glycerol phosphate synthase Cag_0174 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 78188743 Common argC N-acetyl-gamma-glutamyl-phosphate reductase Cag_0772 217 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 78189455 Common - hypothetical protein Cag_1494 20 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 78189496 Nonpathogen - hypothetical protein Cag_1536 1 None None None 78189662 Common - hypothetical protein Cag_1706 211 COG0313 COG0313, Predicted methyltransferases General function prediction only 78189194 Common - transcriptional regulator, Fis family Cag_1228 172 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 78188399 Common - 6-pyruvoyl tetrahydrobiopterin synthase, putative Cag_0421 62 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 78188525 Common - collagenase Cag_0547 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 78189768 Common - hypothetical protein Cag_1812 26 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 78189850 Common - hypothetical protein Cag_1895 10 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 78189345 Common - carbohydrate kinase, PfkB family Cag_1382 114 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 78188290 Common - hypothetical protein Cag_0311 35 None None None 78189263 Common - hypothetical protein Cag_1298 19 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 78189476 Common hemA glutamyl-tRNA reductase Cag_1516 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 78189729 Common - hypothetical protein Cag_1773 88 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 78188940 Common - Secretion protein HlyD Cag_0972 162 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 78189378 Common - DNA helicase II Cag_1415 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 78188534 Common - Hydrogenase expression/formation protein HypE Cag_0556 150 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 78188650 Common - pyridoxal phosphate-dependent enzyme Cag_0672 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 78188892 Common - oxidoreductase, short-chain dehydrogenase/reductase family Cag_0924 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 78188470 Nonpathogen - hypothetical protein Cag_0492 2 None None None 78188764 Common - 3-beta hydroxysteroid dehydrogenase/isomerase family protein Cag_0793 212 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78189615 Common - glycine dehydrogenase subunit 2 Cag_1658 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 78189248 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Cag_1282 208 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 78188420 Common - Histidine biosynthesis protein HisF Cag_0442 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 78188446 Nonpathogen - hypothetical protein Cag_0468 3 None None None 78188527 Common - MotA/TolQ/ExbB proton channel family protein Cag_0549 145 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 78189602 Common recX recombination regulator RecX Cag_1645 69 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 78188861 Common - metacaspase Cag_0891 25 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 78188087 Common - Elongator protein 3/MiaB/NifB Cag_0104 79 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 78189787 Common secY preprotein translocase subunit SecY Cag_1831 241 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 78189080 Nonpathogen - hypothetical protein Cag_1113 1 None None None 78189845 Nonpathogen - hypothetical protein Cag_1890 3 None None None 78189923 Common - hypothetical protein Cag_1970 72 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 78188372 Common - cytochrome b6-f complex, iron-sulfur subunit Cag_0394 81 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 78189581 Common - hypothetical protein Cag_1623 47 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 78188345 Nonpathogen - hypothetical protein Cag_0367 3 None None None 78189053 Common - Histidinol-phosphate aminotransferase Cag_1086 236 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 78187988 Common - hypothetical protein Cag_0004 118 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 78188954 Common - outer membrane efflux protein, putative Cag_0986 97 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 78189326 Common - hypothetical protein Cag_1361 15 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 78189819 Common - hypothetical protein Cag_1864 49 COG4804 COG4804, Uncharacterized conserved protein Function unknown 78189417 Common gmk guanylate kinase Cag_1456 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 78189494 Common - hypothetical protein Cag_1534 9 None None None 78189570 Nonpathogen - hypothetical protein Cag_1610 1 None None None 78188353 Common - ATPase Cag_0375 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 78189744 Common - 3,4-Dihydroxy-2-butanone 4-phosphate synthase Cag_1788 228 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 78189032 Common moaC bifunctional molybdenum cofactor biosynthesis protein C/molybdopterin-binding protein Cag_1065 196 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 78189667 Common - Phenylalanyl-tRNA synthetase, alpha subunit Cag_1711 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 78189227 Common - putative serine acetyltransferase Cag_1261 190 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 78189645 Common leuS leucyl-tRNA synthetase Cag_1688 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78189810 Common - elongation factor G Cag_1854 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 78189469 Nonpathogen - hypothetical protein Cag_1508 1 None None None 78189866 Common - OmpA domain protein Cag_1911 144 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 78189551 Common - hypothetical protein Cag_1591 42 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 78188510 Nonpathogen - hypothetical protein Cag_0532 2 None None None 78188718 Common - Type I secretion outer membrane protein, TolC Cag_0744 144 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 78188783 Common - hypothetical protein Cag_0812 14 None None None 78189172 Common - Na+/H+ anti-porter Cag_1205 32 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 78189715 Common - 7-cyano-7-deazaguanine reductase Cag_1759 117 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 78189653 Nonpathogen - hypothetical protein Cag_1697 1 None None None 78189066 Common - DNA modification methylase-like Cag_1099 104 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 78189321 Common - cytochrome-cbb3 oxidase, subunit I Cag_1356 147 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 78189307 Nonpathogen - hypothetical protein Cag_1342 1 COG3698 COG3698, Predicted periplasmic protein Function unknown 78188988 Common - hypothetical protein Cag_1021 12 None None None 78189272 Common - hypothetical protein Cag_1307 41 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 78189979 Common - glycerol-3-phosphate dehydrogenase, NAD-dependent Cag_2026 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 78189095 Common - alcohol dehydrogenase, iron-containing Cag_1128 165 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 162319769 Common rplX 50S ribosomal protein L24 Cag_1840 208 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 78188859 Common - transporter, putative Cag_0889 34 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 78188113 Common - Uroporphyrinogen decarboxylase HemE Cag_0130 182 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 78188431 Common - ATPase Cag_0453 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 78188326 Nonpathogen - hypothetical protein Cag_0348 3 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 78188002 Common - prephenate dehydrogenase Cag_0018 150 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 78189414 Common - TPR repeat Cag_1453 65 None None None 78188425 Common - hypothetical protein Cag_0447 72 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78189037 Common - hypothetical protein Cag_1070 38 COG1814 COG1814, Uncharacterized membrane protein Function unknown 78188000 Common - hypothetical protein Cag_0016 12 COG2361 COG2361, Uncharacterized conserved protein Function unknown 78189386 Common - Molecular chaperone GrpE (heat shock protein)-like Cag_1423 228 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 78189152 Common - Transglutaminase-like Cag_1185 95 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 78189974 Common prmA ribosomal protein L11 methyltransferase Cag_2021 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 78188566 Common - hypothetical protein Cag_0588 48 COG4637 COG4637, Predicted ATPase General function prediction only 78188209 Common - 8-amino-7-oxononanoate synthase Cag_0226 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 78188844 Common - hypothetical protein Cag_0874 48 COG4804 COG4804, Uncharacterized conserved protein Function unknown 78188519 Common - putative transcriptional regulator Cag_0541 147 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 78189692 Nonpathogen - hypothetical protein Cag_1736 2 None None None 78189566 Common - hypothetical protein Cag_1606 3 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 78189385 Common - Heat shock protein DnaJ Cag_1422 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 78189867 Common - TPR repeat Cag_1912 92 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 78188384 Common - Alkaline phosphatase Cag_0406 149 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 78189213 Common - Nitrogenase molybdenum-iron protein alpha chain Cag_1247 55 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 78188970 Nonpathogen - hypothetical protein Cag_1003 2 None None None 78189590 Common rpsU 30S ribosomal protein S21 Cag_1632 16 None None None 78188461 Common - Ham1-like protein Cag_0483 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 78188331 Common rplK 50S ribosomal protein L11 Cag_0353 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 78189710 Common - aldehyde dehydrogenase Cag_1754 218 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 78188220 Common - peptidase, M16 family Cag_0239 194 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 78189043 Common - hypothetical protein Cag_1076 8 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 78188852 Common - sulfide-quinone reductase, putative Cag_0882 41 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 78189020 Common - Filamentous haemagglutinin-like Cag_1053 91 None None None 78188667 Nonpathogen - hypothetical protein Cag_0691 2 None None None 78187992 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Cag_0008 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 78189350 Common - ATP-dependent endonuclease of the OLD family-like Cag_1387 19 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 78188103 Nonpathogen - hypothetical protein Cag_0120 3 None None None 78189598 Common - aldolase Cag_1641 67 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 78189439 Common - glycosyl transferase Cag_1478 167 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 78189359 Common - hypothetical protein Cag_1396 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 78189958 Common - sulfide dehydrogenase, cytochrome subunit Cag_2005 50 COG2863 COG2863, Cytochrome c553 Energy production and conversion 78188490 Common - Glucose-1-phosphate thymidylyltransferase, long form Cag_0512 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 78189954 Common - hypothetical protein Cag_2001 7 None None None 78188731 Common - Cobalamin biosynthesis protein CbiB Cag_0757 146 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 78188607 Common - Hit family protein Cag_0629 94 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 78188031 Common - methyltransferase Cag_0047 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 78188612 Common - NADH dehydrogenase I, subunit 3 Cag_0634 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 78188837 Nonpathogen - hypothetical protein Cag_0867 3 None None None 78188998 Nonpathogen - hydrogenase, iron-sulfur binding protein, putative Cag_1031 25 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 78189638 Common - cytochrome c biogenesis protein Cag_1681 152 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 78189859 Nonpathogen - hypothetical protein Cag_1904 1 None None None 78188975 Common - CRISPR-associated CT1133 family protein Cag_1008 16 None None None 78188725 Nonpathogen - hypothetical protein Cag_0751 2 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78188166 Common clpX ATP-dependent protease ATP-binding subunit Cag_0183 209 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 78188928 Common - bifunctional methionine sulfoxide reductase B/A protein Cag_0960 206 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 78188788 Common - Phosphomethylpyrimidine kinase Cag_0817 216 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 78188540 Common - putative PAS/PAC sensor protein Cag_0562 33 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 78189185 Common - pantothenate kinase Cag_1218 99 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 78189630 Common - 2-isopropylmalate synthase Cag_1673 210 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 78188260 Nonpathogen - hypothetical protein Cag_0279 1 None None None 78188609 Common - ferrochelatase, putative Cag_0631 8 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 78189521 Common - zinc protease, putative Cag_1561 148 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 78188807 Common - hypothetical protein Cag_0836 7 COG4891 COG4891, Uncharacterized conserved protein Function unknown 78188966 Common - hypothetical protein Cag_0999 6 None None None 78188448 Nonpathogen - hypothetical protein Cag_0470 4 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 78189007 Nonpathogen - hypothetical protein Cag_1040 5 None None None 78188637 Nonpathogen - hypothetical protein Cag_0659 1 None None None 78189881 Common - thiol:disulfide interchange protein, thioredoxin family Cag_1928 135 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 78188379 Common - 2-desacetyl-2-hydroxyethyl bacteriochlorophyllide Cag_0401 142 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 78188882 Common - hypothetical protein Cag_0913 4 COG4679 COG4679, Phage-related protein Function unknown 78189393 Common - hypothetical protein Cag_1431 20 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 78189938 Nonpathogen - Cold shock protein Cag_1985 3 COG1432 COG1432, Uncharacterized conserved protein Function unknown 78188715 Nonpathogen - hypothetical protein Cag_0739 1 None None None 78189943 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase Cag_1990 140 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 78189108 Nonpathogen - hypothetical protein Cag_1141 11 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 78189963 Common - transporter, putative Cag_2010 159 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 78188077 Common rpsF 30S ribosomal protein S6 Cag_0094 20 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 78189195 Common - homocitrate synthase Cag_1229 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 78188115 Common - 6,7-dimethyl-8-ribityllumazine synthase Cag_0132 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 78188581 Common - RecJ exonuclease Cag_0603 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 78189876 Common - Twin-arginine translocation pathway signal Cag_1923 36 COG5501 COG5501, Predicted secreted protein Function unknown 78188132 Common - NusG antitermination factor Cag_0149 169 COG0250 NusG, Transcription antiterminator Transcription 78189982 Common - Phosphoesterase, PA-phosphatase related Cag_2029 98 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 78188175 Common - hypothetical protein Cag_0192 72 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 78188126 Common - Competence-damaged protein Cag_0143 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 78188716 Common - Type I secretion system ATPase, PrtD Cag_0740 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 78189119 Common - OmpA family protein Cag_1152 171 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 78188773 Common trmD tRNA (guanine-N(1)-)-methyltransferase Cag_0802 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 78188051 Common - F0F1 ATP synthase subunit delta Cag_0067 178 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 78189951 Common - nitrogen regulatory protein P-II (GlnB, GlnK) Cag_1998 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 78188199 Common - response regulator receiver domain protein (CheY-like) Cag_0216 7 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 78189591 Nonpathogen - hypothetical protein Cag_1633 3 None None None 78189430 Common - Death-on-curing protein Cag_1469 63 COG3943 COG3943, Virulence protein General function prediction only 78188535 Common - cobalamin biosynthesis protein CbiM, putative Cag_0557 49 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 78189004 Nonpathogen - hypothetical protein Cag_1037 1 None None None 78188433 Common - hypothetical protein Cag_0455 4 None None None 78188677 Common - hypothetical protein Cag_0701 23 COG4832 COG4832, Uncharacterized conserved protein Function unknown 78189949 Common - putative segregation and condensation protein A Cag_1996 142 COG1354 COG1354, Uncharacterized conserved protein Function unknown 78188183 Common - competence protein Cag_0200 171 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 78189291 Common - hypothetical protein Cag_1326 110 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 78189123 Common - 50S ribosomal protein L25/general stress protein Ctc Cag_1156 136 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 78189426 Nonpathogen - hypothetical protein Cag_1465 1 None None None 78189936 Common - Alpha amylase, catalytic subdomain Cag_1983 173 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 78188546 Common - rod shape-determining protein RodA Cag_0568 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 78189903 Common - DsrH protein Cag_1950 25 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 78189390 Nonpathogen - hypothetical protein Cag_1428 3 None None None 78189660 Common - Peptidase S49, protease IV Cag_1704 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 78188223 Common - Dihydrouridine synthase TIM-barrel protein nifR3 Cag_0242 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 78188636 Common - transposase Cag_0658 58 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78189151 Common - hypothetical protein Cag_1184 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 78189433 Common - glycosyl transferase Cag_1472 199 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78189599 Common - short chain dehydrogenase Cag_1642 235 COG3347 COG3347, Uncharacterized conserved protein Function unknown 78189723 Common ruvB Holliday junction DNA helicase B Cag_1767 216 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 78189732 Nonpathogen - hypothetical protein Cag_1776 2 None None None 78188972 Common - Protein of unknown function DUF48 Cag_1005 98 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 78189397 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Cag_1435 165 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 78188585 Common - Phosphoesterase, PA-phosphatase related Cag_0607 70 None None None 78188467 Common - IMP dehydrogenase Cag_0489 239 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 78188001 Common pyrE orotate phosphoribosyltransferase Cag_0017 77 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 78188967 Nonpathogen - hypothetical protein Cag_1000 3 None None None 78189811 Common - 30S ribosomal protein S7 Cag_1855 246 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 78189878 Common - sulfur oxidation protein SoxA Cag_1925 26 COG3258 COG3258, Cytochrome c Energy production and conversion 78189832 Nonpathogen - hypothetical protein Cag_1877 3 None None None 78188161 Common - Membrane proteins related to metalloendopeptidase-like Cag_0178 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 78187994 Common prfA peptide chain release factor 1 Cag_0010 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 78188264 Common - SugE protein Cag_0283 144 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 78189217 Common - Nitrogenase cofactor biosynthesis protein NifB Cag_1251 69 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 78188886 Common - cytochrome c family protein Cag_0918 23 None None None 78189603 Common - Uridylate kinase Cag_1646 243 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 78188400 Common - Para-aminobenzoate synthase, component I Cag_0422 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 78188213 Common - 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK Cag_0230 200 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 78189794 Common rpsN 30S ribosomal protein S14 Cag_1838 211 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 78189879 Nonpathogen - hypothetical protein Cag_1926 1 None None None 78188168 Common gltD glutamate synthase subunit beta Cag_0185 186 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 78188306 Common - ATP-dependent DNA helicase RecG Cag_0328 230 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 78189274 Common - methylase Cag_1309 43 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 78188839 Common - ATPase Cag_0869 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 78189555 Common - DeoxyUTP pyrophosphatase subfamily 1 Cag_1595 176 COG0756 Dut, dUTPase Nucleotide transport and metabolism 78188085 Common - transcriptional regulator, XRE family Cag_0102 12 None None None 78188599 Common - cytosolic long-chain acyl-CoA thioester hydrolase family protein Cag_0621 97 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 78189574 Common - RfaE bifunctional protein, domain II Cag_1616 145 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 78188999 Common - hydrogenase/sulfur reductase, beta subunit Cag_1032 31 None None None 78188149 Common - putative transcriptional regulator Cag_0166 72 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 78188335 Common rpoB DNA-directed RNA polymerase subunit beta Cag_0357 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 78189342 Common - Peptidoglycan-binding LysM Cag_1379 153 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 78188736 Common - Exodeoxyribonuclease V, RecC subunit Cag_0763 67 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 78188962 Nonpathogen - hypothetical protein Cag_0994 1 None None None 78188285 Nonpathogen - hypothetical protein Cag_0304 3 None None None 78188622 Common - Proton-translocating NADH-quinone oxidoreductase, chain N Cag_0644 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 78189381 Common - phosphatidylglycerophosphatase A Cag_1418 102 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 78189587 Common - hypothetical protein Cag_1629 43 None None None 78189691 Common - SpoU rRNA methylase family protein Cag_1735 205 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 78189972 Common - exopolyphosphatase, putative Cag_2019 165 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 78188521 Common - hypothetical protein Cag_0543 8 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 78188314 Common - Secretion protein HlyD Cag_0336 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 78189388 Common - Modification methylase HemK Cag_1425 229 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 78189533 Nonpathogen - hypothetical protein Cag_1573 3 None None None 78188810 Common - hypothetical protein Cag_0839 13 None None None 78189774 Common cysS cysteinyl-tRNA synthetase Cag_1818 243 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78188294 Common - hypothetical protein Cag_0316 69 COG1432 COG1432, Uncharacterized conserved protein Function unknown 78189498 Common - bacteriochlorophyll c synthase Cag_1538 56 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 78188592 Common - Parallel beta-helix repeat Cag_0614 171 None None None 78188366 Common valS valyl-tRNA synthetase Cag_0388 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78188292 Common - excinuclease ABC subunit B Cag_0314 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 78188231 Nonpathogen - chlorosome envelope protein E Cag_0250 3 None None None 78189758 Common - Methylpurine-DNA glycosylase (MPG) Cag_1802 84 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 78188344 Common - 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit Cag_0366 107 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 78189059 Common - hypothetical protein Cag_1092 66 COG4717 COG4717, Uncharacterized conserved protein Function unknown 78189716 Common - hypothetical protein Cag_1760 33 COG3897 COG3897, Predicted methyltransferase General function prediction only 78189444 Common - acyltransferase, HtrB/MsbB family Cag_1483 119 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 78188910 Common - carbon-nitrogen hydrolase family protein Cag_0942 201 COG0388 COG0388, Predicted amidohydrolase General function prediction only 78188483 Common - radical activating enzyme, putative Cag_0505 145 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 78188032 Nonpathogen - hypothetical protein Cag_0048 3 None None None 78188706 Common - Argininosuccinate lyase Cag_0730 232 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 78188451 Common - sigma-24 (FecI-like) Cag_0473 166 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 78189898 Common - polysulfide reductase, subunit B, putative Cag_1945 165 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 78188560 Nonpathogen - hypothetical protein Cag_0582 1 None None None 78189036 Nonpathogen - hypothetical protein Cag_1069 4 None None None 78189821 Common - putative DNA-binding protein Cag_1866 61 COG3943 COG3943, Virulence protein General function prediction only 78189955 Common - putative ferric uptake regulator, FUR family Cag_2002 122 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 78189415 Common - glutathione S-transferase, fosfomycin resistance protein, putative Cag_1454 27 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 78189181 Nonpathogen - hypothetical protein Cag_1214 4 None None None 78188357 Common - hypothetical protein Cag_0379 51 COG4804 COG4804, Uncharacterized conserved protein Function unknown 78189563 Common - NUDIX/MutT family protein Cag_1603 110 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 78188629 Common - GDP-L-fucose synthetase Cag_0651 194 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78189538 Common - hypothetical protein Cag_1578 10 None None None 78188192 Common - bacteriochlorophyll c synthase Cag_0209 67 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 78189747 Common - hypothetical protein Cag_1791 47 COG2968 COG2968, Uncharacterized conserved protein Function unknown 78189362 Common - hypothetical protein Cag_1399 54 COG1808 COG1808, Predicted membrane protein Function unknown 78188722 Common - transposase Cag_0748 58 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188662 Common - hypothetical protein Cag_0685 10 None None None 78189079 Nonpathogen - hypothetical protein Cag_1112 5 None None None 78188385 Common - protein tyrosine phosphatase Cag_0407 134 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 78189228 Common - hypothetical protein Cag_1262 12 None None None 78189978 Common - Protein of unknown function DUF205 Cag_2025 169 COG0344 COG0344, Predicted membrane protein Function unknown 78189633 Common - ABC 3 transport family protein Cag_1676 188 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 78189678 Common - hypothetical protein Cag_1722 12 None None None 78189486 Common - Restriction endonuclease S subunits-like Cag_1526 66 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 78188947 Common - ATPase Cag_0979 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 78189052 Nonpathogen - hypothetical protein Cag_1085 3 None None None 78189883 Common - ferrous iron transport protein A Cag_1930 62 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 78189924 Common - hypothetical protein Cag_1971 4 None None None 78188329 Common secE preprotein translocase subunit SecE Cag_0351 8 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 78189520 Common - VCBS Cag_1560 92 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 78189761 Common - Dihydrodipicolinate reductase Cag_1805 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 78188067 Common - Adenosylmethionine--8-amino-7-oxononanoate aminotransferase Cag_0083 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 78189112 Common - hypothetical protein Cag_1145 6 None None None 78188234 Common - hypothetical protein Cag_0253 13 None None None 78189586 Common - C-5 cytosine-specific DNA methylase Cag_1628 109 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 78188756 Common - hypothetical protein Cag_0785 9 COG5346 COG5346, Predicted membrane protein Function unknown 78188322 Nonpathogen - photosystem P840 reaction center iron-sulfur protein Cag_0344 6 COG1146 COG1146, Ferredoxin Energy production and conversion 78188465 Common - Methionyl-tRNA formyltransferase Cag_0487 220 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 78188495 Common - UDP-glucose 4-epimerase Cag_0517 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 78188799 Common - Primosomal protein n Cag_0828 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 78188458 Common - putative ABC transport system permease protein Cag_0480 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 78189163 Common - adenine specific DNA methyltransferase Cag_1196 33 COG4889 COG4889, Predicted helicase General function prediction only 78189262 Common - tryptophan synthase subunit beta Cag_1297 226 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 78188642 Common - putative transcriptional regulator Cag_0664 59 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 78188412 Nonpathogen - hypothetical protein Cag_0434 1 None None None 78189611 Common - ATPase Cag_1654 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 78189364 Common - hypothetical protein Cag_1401 4 None None None 78188945 Common - hypothetical protein Cag_0977 16 COG5607 COG5607, Uncharacterized conserved protein Function unknown 78188277 Common - hypothetical protein Cag_0296 12 None None None 78189655 Nonpathogen - hypothetical protein Cag_1699 1 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 78189450 Common - hypothetical protein Cag_1489 14 COG1434 COG1434, Uncharacterized conserved protein Function unknown 78188790 Nonpathogen - hypothetical protein Cag_0819 1 None None None 78189617 Common - 3-oxoacyl-(acyl-carrier-protein) synthase II Cag_1660 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 78188398 Common - Dihydropteroate synthase Cag_0420 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 78188645 Common - hypothetical protein Cag_0667 4 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 78188766 Common - prolipoprotein diacylglyceryl transferase Cag_0795 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 78188177 Common - hypothetical protein Cag_0194 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 78188848 Common - hypothetical protein Cag_0878 4 None None None 78188440 Common - hypothetical protein Cag_0462 76 COG1259 COG1259, Uncharacterized conserved protein Function unknown 78189170 Common - Hydrophobe/amphiphile efflux-1 HAE1 Cag_1203 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 78188746 Common - Ornithine carbamoyltransferase Cag_0775 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 78188449 Nonpathogen - hypothetical protein Cag_0471 4 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 78189100 Nonpathogen - hypothetical protein Cag_1133 4 None None None 78188058 Common - putative translaldolase Cag_0074 158 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 78189406 Common - isopentenyl pyrophosphate isomerase Cag_1445 80 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 78188308 Common - aldehyde dehydrogenase family protein Cag_0330 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 78188730 Common - hypothetical protein Cag_0756 119 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 78189132 Nonpathogen - hypothetical protein Cag_1165 3 None None None 78189475 Common - Porphobilinogen deaminase Cag_1515 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 78189763 Common - Histidinol-phosphate phosphatase Cag_1807 122 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 78188259 Nonpathogen - hypothetical protein Cag_0278 1 None None None 78188419 Common - hypothetical protein Cag_0441 8 None None None 78189177 Nonpathogen - hypothetical protein Cag_1210 1 None None None 78189023 Common - Hemolysin activation/secretion protein-like Cag_1056 51 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 78188865 Common - hypothetical protein Cag_0895 92 COG3153 COG3153, Predicted acetyltransferase General function prediction only 78188574 Common - acetyltransferase, GNAT family Cag_0596 86 COG3153 COG3153, Predicted acetyltransferase General function prediction only 78189304 Common - putative sugar transport protein Cag_1339 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 78189719 Common - hypothetical protein Cag_1763 11 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 78188150 Common - isoprenoid biosynthesis protein with amidotransferase-like domain Cag_0167 38 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 78189553 Common - glycosyl transferase Cag_1593 77 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 78189507 Common - S-adenosylmethionine synthetase Cag_1547 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 78188503 Common - Amidophosphoribosyl transferase Cag_0525 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 78188695 Common - hypothetical protein Cag_0719 69 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 78189341 Common - Anion-transporting ATPase Cag_1378 91 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 78188250 Nonpathogen - hypothetical protein Cag_0269 2 None None None 78188656 Common - Protein of unknown function DUF132 Cag_0679 24 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78189090 Common - hypothetical protein Cag_1123 13 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188504 Nonpathogen - hypothetical protein Cag_0526 2 None None None 78188351 Common - 6-pyruvoyltetrahydropterin synthase Cag_0373 76 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 78189255 Common - Histidinol dehydrogenase Cag_1289 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 78189180 Common - Thiamine-monophosphate kinase Cag_1213 185 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 78188665 Common - PucC protein Cag_0689 24 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 78189467 Common - hypothetical protein Cag_1506 11 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 78189278 Common - ExsB Cag_1313 177 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 78189857 Common - ketol-acid reductoisomerase Cag_1902 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 78189348 Common - hypothetical protein Cag_1385 3 None None None 78189545 Common - adenylylsulfate reductase Cag_1585 88 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 78189192 Common - hypothetical protein Cag_1226 40 COG4637 COG4637, Predicted ATPase General function prediction only 78188028 Common pgk phosphoglycerate kinase Cag_0044 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 78189413 Common - hypothetical protein Cag_1452 9 None None None 78189913 Common - Rhodanese-like Cag_1960 104 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 78188288 Common - hypothetical protein Cag_0309 19 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 78189300 Nonpathogen - hypothetical protein Cag_1335 2 None None None 78189968 Common - ATP synthase F1, epsilon subunit Cag_2015 142 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 78189625 Common - glucose-6-phosphate 1-dehydrogenase Cag_1668 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 78188158 Common - Ribulose-phosphate 3-epimerase Cag_0175 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 78188117 Nonpathogen - hypothetical protein Cag_0134 1 None None None 78188003 Common - putative NAD+ kinase Cag_0019 238 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 78189045 Common - transcriptional regulator, AbrB family Cag_1078 9 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 78189484 Common dinD DNA-damage-inducible protein D Cag_1524 20 None None None 78189329 Common - hypothetical protein Cag_1364 2 None None None 78188471 Common - Anthranilate synthase component I Cag_0493 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 78189315 Common - hypothetical protein Cag_1350 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 78189153 Common - hypothetical protein Cag_1186 12 COG2267 PldB, Lysophospholipase Lipid metabolism 78189447 Common - toluene transport protein, putative Cag_1486 37 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 78188181 Common - UDP-N-acetylglucosamine acyltransferase Cag_0198 162 COG1043 LpxA, Acyl- acyl carrier protein 78188977 Common - CRISPR-associated helicase Cas3, core Cag_1010 79 COG1203 COG1203, Predicted helicases General function prediction only 78188826 Common - hypothetical protein Cag_0856 93 COG1262 COG1262, Uncharacterized conserved protein Function unknown 78188211 Common - Mg-protoporphyrin IX methyl transferase Cag_0228 122 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 78189827 Common - exodeoxyribonuclease, small subunit Cag_1872 16 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 78188315 Common - ATPase Cag_0337 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 78188934 Nonpathogen - hypothetical protein Cag_0966 3 None None None 78188846 Common - DNA photolyase, class 2 Cag_0876 98 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 78189665 Common - hypothetical protein Cag_1709 37 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 78189905 Common - DsrE protein Cag_1952 49 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 78188951 Common - Magnesium-chelatase, subunit H Cag_0983 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 78188682 Nonpathogen - hypothetical protein Cag_0706 1 None None None 78188982 Common - hypothetical protein Cag_1015 14 None None None 78188111 Common - Succinate dehydrogenase/fumarate reductase iron-sulfur protein Cag_0128 207 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 78188218 Common - killer suppression protein HigA, putative Cag_0237 8 None None None 78188134 Common - hypothetical protein Cag_0151 10 None None None 78189203 Common - arginine/ornithine transport system ATPase Cag_1237 100 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 78188880 Nonpathogen - hypothetical protein Cag_0911 4 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 78188241 Nonpathogen - hypothetical protein Cag_0260 2 COG4575 ElaB, Uncharacterized conserved protein Function unknown 78189706 Common - hypothetical protein Cag_1750 9 COG4627 COG4627, Uncharacterized protein conserved in bacteria Function unknown 78188204 Common - Anion-transporting ATPase Cag_0221 98 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 78189242 Common - Dihydrolipoamide dehydrogenase Cag_1276 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 78189204 Common - hypothetical protein Cag_1238 4 None None None 78189146 Common - hypothetical protein Cag_1179 16 COG4715 COG4715, Uncharacterized conserved protein Function unknown 78188409 Common - polyphosphate kinase Cag_0431 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 78188105 Common - LipD protein, putative Cag_0122 111 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 78188757 Nonpathogen - hypothetical protein Cag_0786 1 None None None 78189373 Common - Isocitrate dehydrogenase NADP-dependent, monomeric type Cag_1410 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 78188876 Common - lipoate-protein ligase A, putative Cag_0906 49 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 78189311 Common - Peptidase A8, signal peptidase II Cag_1346 199 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 78189675 Common - naphthoate synthase Cag_1719 181 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 78189932 Common - bacterioferritin Cag_1979 49 COG2406 COG2406, Protein distantly related to bacterial ferritins General function prediction only 78189838 Common - Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like Cag_1883 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 78189734 Common - DNA polymerase III, delta subunit, putative Cag_1778 213 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 78189074 Common - ComEC/Rec2-related protein Cag_1107 155 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 78188225 Common - hydrogenase/sulfur reductase, delta subunit Cag_0244 51 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 78188987 Common - YjeF-related protein-like Cag_1020 219 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 78189518 Common - hypothetical protein Cag_1558 15 None None None 78188830 Common - Fe-S type hydro-lyase tartrate/fumarate alpha and beta region Cag_0860 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 78188600 Common - deoxycytidylate deaminase, putative Cag_0622 85 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 78188803 Common - transposase Cag_0832 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188776 Common - Signal recognition particle protein Cag_0805 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 78188370 Common - Glutamyl-tRNA synthetase Cag_0392 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 78188921 Common - polysulfide reductase, subunit B, putative Cag_0953 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 78189333 Common - Cytochrome oxidase maturation protein cbb3-type Cag_1370 4 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 78189029 Nonpathogen - hypothetical protein Cag_1062 3 None None None 78189187 Common - shikimate kinase Cag_1220 202 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 78188969 Nonpathogen - hypothetical protein Cag_1002 4 None None None 78188729 Common - hypothetical protein Cag_0755 12 None None None 78189425 Common - hypothetical protein Cag_1464 77 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 78189628 Common - hypothetical protein Cag_1671 12 None None None 78189557 Common - hypothetical protein Cag_1597 62 None None None 78188884 Common - C-type cytochrome, putative Cag_0916 6 COG3474 COG3474, Cytochrome c2 Energy production and conversion 78189015 Common - hypothetical protein Cag_1048 66 None None None 78189792 Common rplF 50S ribosomal protein L6 Cag_1836 230 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 78188822 Common - branched-chain amino acid ABC transporter, permease protein Cag_0852 152 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 78188991 Common - hypothetical protein Cag_1024 12 None None None 78188867 Nonpathogen - hypothetical protein Cag_0897 3 None None None 78188749 Common - DNA repair protein RadA Cag_0778 207 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 78188974 Common - CRISPR-associated TM1801 family protein Cag_1007 54 COG3649 COG3649, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 78188619 Common - NADH dehydrogenase I subunit 4L Cag_0641 17 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 78188283 Common - hypothetical protein Cag_0302 137 COG0795 COG0795, Predicted permeases General function prediction only 78188163 Common - prephenate dehydratase Cag_0180 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 78188908 Common - hypothetical protein Cag_0940 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 78189976 Common - Aspartate kinase region Cag_2023 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 78189198 Common - putative aldo/keto reductase Cag_1232 199 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 78188364 Common - haem catalase/peroxidase Cag_0386 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 78188901 Nonpathogen - DNA polymerase III, gamma/tau subunit Cag_0933 2 None None None 78188337 Common - Acetyl-CoA carboxylase, biotin carboxylase Cag_0359 226 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 78189367 Common - hypothetical protein Cag_1404 57 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 78189688 Common - Glycine cleavage H-protein Cag_1732 183 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 78188310 Common - type II DNA modification methyltransferase M.TdeIII Cag_0332 9 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 78189593 Common - Alanine racemase region Cag_1635 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 78188079 Common rpsR 30S ribosomal protein S18 Cag_0096 212 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 78188792 Common - UDP-glucose/GDP-mannose dehydrogenase family protein Cag_0821 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 78189560 Common - ATPase Cag_1600 35 COG3950 COG3950, Predicted ATP-binding protein involved in virulence General function prediction only 78189926 Common - ATPase Cag_1973 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 78188095 Common - von Willebrand factor, type A Cag_0112 110 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 78188070 Common - transposase Cag_0086 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78189940 Common - hypothetical protein Cag_1987 98 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 78188537 Common - phosphoribosyl-AMP cyclohydrolase Cag_0559 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 78189861 Common - Dihydroxy-acid dehydratase Cag_1906 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 78188178 Common - sodium:solute symporter family protein Cag_0195 168 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 78189848 Common - Heat shock protein Hsp70 Cag_1893 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 78188633 Nonpathogen - hypothetical protein Cag_0655 1 None None None 78189671 Common - Threonyl-tRNA synthetase, class IIa Cag_1715 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78189872 Common - hypothetical protein Cag_1919 114 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 78188979 Common - Cobyric acid synthase CobQ Cag_1012 150 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 78188855 Common - methyltransferase, putative Cag_0885 53 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 78189657 Common - Isochorismate synthase Cag_1701 221 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 78188255 Nonpathogen - hypothetical protein Cag_0274 1 None None None 78189947 Nonpathogen - hypothetical protein Cag_1994 3 None None None 78188544 Common - hypothetical protein Cag_0566 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 78189491 Nonpathogen secG preprotein translocase subunit SecG Cag_1531 3 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 78189121 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase, LpxD Cag_1154 159 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 78189725 Common - Protein of unknown function DUF132 Cag_1769 22 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78189676 Common - thioesterase, menaquinone synthesis protein Cag_1720 177 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 78189435 Common - heptosyltransferase Cag_1474 9 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 78189612 Nonpathogen - FtsK/SpoIIIE family protein Cag_1655 4 None None None 78189246 Nonpathogen - hypothetical protein Cag_1280 3 None None None 78188610 Common - TPR repeat Cag_0632 85 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 78189529 Common - hypothetical protein Cag_1569 10 None None None 78188041 Common - FtsQ protein, putative Cag_0057 8 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 78189103 Common - hypothetical protein Cag_1136 18 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188989 Common - hypothetical protein Cag_1022 95 None None None 78188136 Common - hypothetical protein Cag_0153 5 None None None 78189714 Nonpathogen - photosystem P840 reaction center cytochrome c-551 Cag_1758 3 None None None 78189442 Common - Glycosyltransferase-like Cag_1481 161 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78188895 Common - Beta-phosphoglucomutase hydrolase Cag_0927 107 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 78188638 Common - hypothetical protein Cag_0660 32 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 78188124 Common - H+-transporting two-sector ATPase, gamma subunit Cag_0141 207 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 78189083 Common - DEAD/DEAH box helicase-like Cag_1116 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 78188415 Common - hypothetical protein Cag_0437 69 COG0795 COG0795, Predicted permeases General function prediction only 78189463 Nonpathogen - hypothetical protein Cag_1502 1 None None None 78189911 Common - Cobyrinic acid a,c-diamide synthase CbiA Cag_1958 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 78188171 Common - hypothetical protein Cag_0188 92 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 78188984 Common - HhH-GPD Cag_1017 20 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 78189068 Common - putative transcriptional regulator Cag_1101 59 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 78189285 Common - Elongator protein 3/MiaB/NifB Cag_1320 86 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 78188528 Common - hypothetical protein Cag_0550 6 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 78188557 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Cag_0579 180 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 78188006 Common - patatin family protein Cag_0022 30 COG3621 COG3621, Patatin General function prediction only 78189813 Common - hypothetical protein Cag_1857 14 COG5617 COG5617, Predicted integral membrane protein Function unknown 78188236 Common - iron-sulfur cluster-binding protein Cag_0255 132 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 78188386 Common - sodium/bile acid symporter family protein Cag_0408 129 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 78188463 Nonpathogen - hypothetical protein Cag_0485 6 None None None 78189930 Common mazG nucleoside triphosphate pyrophosphohydrolase Cag_1977 155 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 78189649 Common metH B12-dependent methionine synthase Cag_1692 178 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 78188090 Common - carbamoyl phosphate synthase small subunit Cag_0107 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 78189097 Common - hypothetical protein Cag_1130 7 None None None 78188660 Nonpathogen - hypothetical protein Cag_0683 1 None None None 78188233 Nonpathogen - hypothetical protein Cag_0252 4 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 78188355 Common - hypothetical protein Cag_0377 11 None None None 78188037 Common - UDP-N-acetylmuramoylalanine-D-glutamate ligase Cag_0053 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 78189050 Common - PhoH family protein Cag_1083 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 78189199 Common - Band 7 protein Cag_1233 210 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 78189785 Common - Translation initiation factor IF-1 Cag_1829 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 78189635 Nonpathogen - hypothetical protein Cag_1678 3 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 78189353 Nonpathogen - hypothetical protein Cag_1390 4 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 78188734 Common - hypothetical protein Cag_0761 16 None None None 78188631 Common - transcriptional modulator of MazE/toxin, MazF Cag_0653 9 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 78188435 Common - DNA recombination protein, RuvA Cag_0457 208 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 78189114 Nonpathogen - hypothetical protein Cag_1147 1 None None None 78188485 Nonpathogen - hypothetical protein Cag_0507 7 None None None 78188523 Common - hypothetical protein Cag_0545 8 None None None 78189221 Common - Outer membrane protein and related peptidoglycan-associated (lipo)proteins-like Cag_1255 164 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 78188562 Common - hypothetical protein Cag_0584 13 COG3905 COG3905, Predicted transcriptional regulator Transcription 78189473 Common radC DNA repair protein RadC Cag_1513 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 78188912 Common - thioredoxin reductase, putative Cag_0944 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 78189322 Common - cytochrome-c oxidase fixO chain Cag_1357 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 78189276 Common - hypothetical protein Cag_1311 12 COG4226 HicB, Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters Function unknown 78188514 Common - Hydrogenase expression/synthesis, HypA Cag_0536 85 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 78188714 Common - VCBS Cag_0738 165 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 78188083 Common trmE tRNA modification GTPase TrmE Cag_0100 220 COG0486 ThdF, Predicted GTPase General function prediction only 78188376 Common - hypothetical protein Cag_0398 101 COG0701 COG0701, Predicted permeases General function prediction only 78189572 Common - DNA/pantothenate metabolism flavoprotein Cag_1614 235 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 78188119 Nonpathogen - hypothetical protein Cag_0136 1 None None None 78189531 Nonpathogen - hypothetical protein Cag_1571 2 None None None 78189337 Nonpathogen - hypothetical protein Cag_1374 1 None None None 78188296 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C Cag_0318 162 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 78189651 Common - reverse transcriptase family protein Cag_1695 65 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 78188453 Common - Glycosyl transferase, family 19 Cag_0475 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 78188703 Common - NUDIX/MutT family protein Cag_0727 82 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 78189057 Common hppA membrane-bound proton-translocating pyrophosphatase Cag_1090 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 78189317 Nonpathogen - hypothetical protein Cag_1352 1 None None None 78189509 Common - N-(5'-phosphoribosyl)-anthranilate isomerase Cag_1549 191 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 78189382 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Cag_1419 180 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 78189740 Common - Alpha-glucan phosphorylase Cag_1784 141 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 78189092 Common - propionate--CoA ligase Cag_1125 220 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 78189843 Common - carotenoid isomerase, putative Cag_1888 92 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 78188785 Common - hypothetical protein Cag_0814 99 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 78189183 Common - hypothetical protein Cag_1216 20 COG2044 COG2044, Predicted peroxiredoxins General function prediction only 162319771 Common - hydroxylamine reductase Cag_1490 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 78188578 Nonpathogen - hypothetical protein Cag_0600 1 None None None 78188690 Nonpathogen - hypothetical protein Cag_0714 1 None None None 78188107 Nonpathogen - hypothetical protein Cag_0124 4 None None None 78189175 Common - Pyridoxal phosphate biosynthetic protein PdxA Cag_1208 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 78189223 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Cag_1257 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 78188252 Common - hypothetical protein Cag_0271 10 None None None 78188914 Common - Peptide chain release factor 3 Cag_0946 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 78188152 Common - Tetraacyldisaccharide-1-P 4'-kinase Cag_0169 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 78188737 Common - transposase Cag_0765 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188627 Common - Uncharacterized protein involved in exopolysaccharide biosynthesis-like Cag_0649 186 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 78189683 Nonpathogen - hypothetical protein Cag_1727 4 None None None 78188021 Common - hypothetical protein Cag_0037 106 COG1262 COG1262, Uncharacterized conserved protein Function unknown 78189257 Nonpathogen - hypothetical protein Cag_1291 2 None None None 78189105 Common - putative metal-dependent hydrolase Cag_1138 61 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 78188286 Nonpathogen - hypothetical protein Cag_0305 4 None None None 78188301 Nonpathogen - hypothetical protein Cag_0323 3 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 78188508 Common - Hydrogenase formation HypD protein Cag_0530 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 78188834 Common rplU 50S ribosomal protein L21 Cag_0864 74 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 78188417 Common - periplasmic sensor signal transduction histidine kinase Cag_0439 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 78188701 Common - drug resistance protein, putative Cag_0725 159 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 78188573 Nonpathogen - hypothetical protein Cag_0595 10 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 78188267 Common - 1-(5-Phosphoribosyl)-5-amino-4-imidazole-carboxylate (AIR) carboxylase Cag_0286 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 78189854 Common - 3-isopropylmalate dehydratase, small subunit Cag_1899 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 78188923 Common - Rhodanese-like Cag_0955 40 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 78187996 Common - Camphor resistance CrcB protein Cag_0012 183 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 78188620 Common - NADH-plastoquinone oxidoreductase, chain 5 Cag_0642 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 78189302 Nonpathogen - hypothetical protein Cag_1337 3 None None None 78188065 Common - Biotin biosynthesis protein BioC Cag_0081 45 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 78188473 Common - GreA/GreB family elongation factor Cag_0495 204 COG0782 GreA, Transcription elongation factor Transcription 78189885 Common - CBS Cag_1932 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 78188014 Common - ferredoxin, 2Fe-2S Cag_0030 57 COG3411 COG3411, Ferredoxin Energy production and conversion 78188543 Common - adenine phosphoribosyltransferase Cag_0565 168 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 78188569 Common - proline iminopeptidase, putative Cag_0591 52 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 78189161 Common - putative plasmid maintenance system antidote protein, XRE family Cag_1194 62 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 78188501 Common ileS isoleucyl-tRNA synthetase Cag_0523 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78189501 Common - hypothetical protein Cag_1541 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 78188640 Common - hypothetical protein Cag_0662 8 None None None 78188442 Common - Di-trans-poly-cis-decaprenylcistransferase Cag_0464 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 78189264 Common - dihydrolipoamide acetyltransferase, putative Cag_1299 143 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 78189772 Common - Adenylosuccinate synthetase Cag_1816 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 78189167 Common - hypothetical protein Cag_1200 21 None None None 78189465 Common - TPR repeat Cag_1504 84 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 78189640 Common - thiol:disulfide interchange protein DsbD Cag_1683 94 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 78188538 Common - Ubiquinone/menaquinone biosynthesis methyltransferase Cag_0560 219 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 78189116 Common - hypothetical protein Cag_1149 10 None None None 78189287 Nonpathogen - hypothetical protein Cag_1322 9 None None None 78189604 Common tsf elongation factor Ts Cag_1647 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 78188350 Common folE GTP cyclohydrolase I Cag_0372 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 78188396 Common - hydrolase, haloacid dehalogenase-like family Cag_0418 47 COG0546 Gph, Predicted phosphatases General function prediction only 78188655 Nonpathogen - hypothetical protein Cag_0678 7 None None None 78188711 Nonpathogen - hypothetical protein Cag_0735 1 None None None 78188421 Common hppA membrane-bound proton-translocating pyrophosphatase Cag_0443 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 78188531 Nonpathogen - hypothetical protein Cag_0553 9 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 78188748 Common - Argininosuccinate synthase Cag_0777 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 78188768 Common - citrate lyase, subunit 2 Cag_0797 214 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 78189408 Common - SMF protein Cag_1447 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 78189751 Nonpathogen - hypothetical protein Cag_1795 1 None None None 78188943 Nonpathogen - chlorosome envelope protein B Cag_0975 3 None None None 78188145 Common - bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase Cag_0162 191 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 78188832 Common - malate dehydrogenase Cag_0862 185 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 78189514 Nonpathogen - hypothetical protein Cag_1554 2 None None None 78189375 Common - Anion-transporting ATPase Cag_1412 87 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 78188874 Nonpathogen - hypothetical protein Cag_0904 3 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 78188759 Common - transposase Cag_0788 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78187991 Common - Peptidase M41, FtsH Cag_0007 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 78188750 Common - methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase Cag_0779 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 78188872 Common - putative transcriptional regulator, XRE family Cag_0902 6 COG0517 COG0517, FOG: CBS domain General function prediction only 78189240 Common - transcriptional regulator, XRE family Cag_1274 10 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 78189236 Common - thiamine biosynthesis protein ThiF Cag_1270 224 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 78188697 Common - hypothetical protein Cag_0721 49 COG4804 COG4804, Uncharacterized conserved protein Function unknown 78188853 Common - hypothetical protein Cag_0883 39 None None None 78189939 Common - protease, putative Cag_1986 185 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 78188958 Common - ABC transporter efflux protein Cag_0990 211 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 78189900 Common - DsrK protein Cag_1947 63 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 78188202 Nonpathogen - chlorosome envelope protein A Cag_0219 3 None None None 78188072 Common - DNA gyrase, subunit A Cag_0088 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 78188248 Common - hypothetical protein Cag_0267 8 None None None 78189148 Common - hypothetical protein Cag_1181 5 None None None 78189621 Common - 3-oxoacyl-(acyl carrier protein) synthase III Cag_1664 220 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 78188402 Common - drug:proton antiporter Cag_0424 138 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 78189298 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Cag_1333 191 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 78189076 Common - Diaminopimelate decarboxylase Cag_1109 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 78189736 Common - phosphofructokinase Cag_1780 157 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 78188043 Common - cell division protein FtsZ Cag_0059 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 78188404 Common - hypothetical protein Cag_0426 26 None None None 78189516 Nonpathogen - hypothetical protein Cag_1556 3 None None None 78189536 Common - hypothetical protein Cag_1576 13 None None None 78189983 Common - Oxa1/60 kDa IMP family protein Cag_2030 210 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 78189627 Common - glycosyl transferase Cag_1670 204 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78188122 Common - homoserine kinase Cag_0139 107 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 78189525 Common - Sua5/YciO/YrdC/YwlC Cag_1565 237 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 78189027 Common - Molybdopterin-guanine dinucleotide biosynthesis MobB region Cag_1060 129 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 78189673 Common - hypothetical protein Cag_1717 17 COG2958 COG2958, Uncharacterized protein conserved in bacteria Function unknown 78188602 Common - thiol peroxidase Cag_0624 107 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 78188801 Common - hypothetical protein Cag_0830 15 None None None 78188671 Common - seryl-tRNA synthetase Cag_0695 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 78189081 Common - DegT/DnrJ/EryC1/StrS family protein Cag_1114 196 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 78189482 Common - Histidinol-phosphate phosphatase, putative, inositol monophosphatase Cag_1522 184 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 78188493 Common - dTDP-4-dehydrorhamnose reductase Cag_0515 169 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 78189766 Nonpathogen - Bacteriochlorophyll 4-vinyl reductase Cag_1810 14 None None None 78189335 Nonpathogen - hypothetical protein Cag_1372 1 None None None 78188195 Common - glycosyl transferase Cag_0212 141 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 78188680 Nonpathogen - hypothetical protein Cag_0704 1 None None None 78188675 Common - DNA mismatch repair protein MutS-like Cag_0699 205 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 78188893 Common - Thymidylate kinase Cag_0925 230 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 78188818 Common - Histone-like DNA-binding protein Cag_0848 206 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 78189346 Common - hypothetical protein Cag_1383 11 None None None 78189962 Common - hypothetical protein Cag_2009 13 None None None 78189825 Common - acetyltransferase Cag_1870 71 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 78189543 Nonpathogen - heterodisulfide reductase, subunit A/hydrogenase, delta subunit, putative Cag_1583 36 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 78189410 Nonpathogen - hypothetical protein Cag_1449 4 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 78189156 Common - RecR protein Cag_1189 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 78188317 Common - Endoglucanase Y-like Cag_0339 37 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 78189717 Nonpathogen - hypothetical protein Cag_1761 3 None None None 78188558 Common - putative NADPH-dependent glutamate synthase small subunit Cag_0580 218 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 78189749 Common - 6-phosphogluconolactonase Cag_1793 107 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 78189562 Common - bacterioferritin comigratory protein, thiol peroxidase, putative Cag_1602 223 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 78188551 Common - Glutamate racemase Cag_0573 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 78189048 Common - D-alanyl-D-alanine carboxypeptidase Cag_1081 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 78189918 Common - Fe-S-cluster-containing hydrogenase components 1-like Cag_1965 165 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 78188088 Nonpathogen - hypothetical protein Cag_0105 1 None None None 78189061 Common - hypothetical protein Cag_1094 107 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 78188903 Common - Ribonuclease BN Cag_0935 113 COG1295 Rbn, Predicted membrane protein Function unknown 78189206 Common - hypothetical protein Cag_1240 25 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 78188939 Common - NolG efflux transporter Cag_0971 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 78189895 Common - Uroporphyrin-III C-methyltransferase-like Cag_1942 205 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 78188410 Common - PhoU Cag_0432 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 78189802 Common rplV 50S ribosomal protein L22 Cag_1846 211 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 78188281 Nonpathogen - hypothetical protein Cag_0300 1 None None None 78189708 Nonpathogen - hypothetical protein Cag_1752 7 None None None 78188824 Nonpathogen - hypothetical protein Cag_0854 1 None None None 78189743 Common - carbamoyl-phosphate synthase, large subunit Cag_1787 234 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 78189409 Common - outer membrane protein OmpH Cag_1448 44 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 78188112 Common - succinate/fumarate oxidoreductase, putative Cag_0129 51 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 78188323 Common - dolichol-phosphate mannosyltransferase Cag_0345 180 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 78188487 Common - hypothetical protein Cag_0509 44 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 78189695 Common - Uncharacterized protein involved in tolerance to divalent cations-like Cag_1739 111 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 78188206 Common - Single-strand binding protein Cag_0223 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 78188076 Common - heptosyltransferase Cag_0093 94 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 78189150 Common - hypothetical protein Cag_1183 90 COG2308 COG2308, Uncharacterized conserved protein Function unknown 78188552 Common - hypothetical protein Cag_0574 4 None None None 78189973 Common - hypothetical protein Cag_2020 4 COG1432 COG1432, Uncharacterized conserved protein Function unknown 78188763 Common - basic membrane protein A Cag_0792 104 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 78189384 Nonpathogen - hypothetical protein Cag_1421 3 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 78188480 Nonpathogen - hypothetical protein Cag_0502 4 None None None 78188476 Common - Phosphate transport system permease protein 1 Cag_0498 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 78189831 Common - ATPase Cag_1876 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 78189286 Nonpathogen - hypothetical protein Cag_1321 1 None None None 78189347 Common - sodium:solute symporter family protein Cag_1384 132 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 78189882 Common - Ferrous iron transport protein B Cag_1929 174 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 78189094 Common - Acetyl-CoA carboxylase alpha subunit-like Cag_1127 220 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 78189271 Common groEL chaperonin GroEL Cag_1306 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 78189836 Nonpathogen - hypothetical protein Cag_1881 1 None None None 78189887 Common sdhA succinate dehydrogenase flavoprotein subunit Cag_1934 225 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 78188086 Common - cytochrome c-555, membrane-bound Cag_0103 44 COG3245 CycB, Cytochrome c5 Energy production and conversion 78189418 Common - hypothetical protein Cag_1457 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 78188123 Common - F0F1 ATP synthase subunit alpha Cag_0140 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 78189327 Nonpathogen - hypothetical protein Cag_1362 1 None None None 78189423 Common infB translation initiation factor IF-2 Cag_1462 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 78189224 Common - Cysteine synthase K/M/A Cag_1258 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 78189583 Common - Helix-hairpin-helix DNA-binding, class 1 Cag_1625 18 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 78188993 Common - C-type lectin Cag_1026 35 None None None 78188887 Common - probable ABC transporter permease protein Cag_0919 137 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 78188787 Common - Thiamine monophosphate synthase Cag_0816 208 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 78188513 Common - hypothetical protein Cag_0535 12 None None None 78188092 Common - Peptidase M22, glycoprotease Cag_0109 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 78189493 Common hisB imidazoleglycerol-phosphate dehydratase Cag_1533 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 78188414 Common - multi-sensor signal transduction histidine kinase Cag_0436 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 78189400 Common - hypothetical protein Cag_1438 212 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 78189355 Common - putative type II DNA modification enzyme (methyltransferase) Cag_1392 106 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 78189783 Common rpsM 30S ribosomal protein S13 Cag_1827 220 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 78189065 Nonpathogen - hypothetical protein Cag_1098 2 None None None 78188751 Common - hypothetical protein Cag_0780 9 None None None 78189056 Common - peptidyl-tRNA hydrolase Cag_1089 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 78188955 Common - Secretion protein HlyD Cag_0987 166 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 78188719 Common - glycosyl transferase, family 25 Cag_0745 8 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 78189582 Nonpathogen - hypothetical protein Cag_1624 3 None None None 78188437 Common rho transcription termination factor Rho Cag_0459 205 COG1158 Rho, Transcription termination factor Transcription 78189942 Common - Ribonuclease E and G Cag_1989 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 78189894 Common - Elongator protein 3/MiaB/NifB Cag_1941 195 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 78188146 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Cag_0163 189 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 78188462 Common - pyridoxal phosphate biosynthetic protein PdxJ Cag_0484 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 78189369 Nonpathogen - hypothetical protein Cag_1406 2 None None None 78188860 Common - Methylated-DNA-(protein)-cysteine S-methyltransferase Cag_0890 219 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 78188239 Common - AICAR transformylase/IMP cyclohydrolase PurH Cag_0258 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 78188858 Common - alcohol dehydrogenase, iron-containing Cag_0888 176 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 78189686 Common - Pyruvate:ferredoxin (flavodoxin) oxidoreductase Cag_1730 112 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 78189394 Common - possible virulence-associated protein Cag_1432 10 None None None 78188056 Common - tryptophanyl-tRNA synthetase Cag_0072 249 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78188881 Common - hypothetical protein Cag_0912 6 None None None 78189595 Nonpathogen - hypothetical protein Cag_1638 4 None None None 78188700 Common - hypothetical protein Cag_0724 12 None None None 78188539 Nonpathogen - hypothetical protein Cag_0561 1 None None None 78189863 Common - ExbD/TolR family protein Cag_1908 140 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 78189874 Common - Twin-arginine translocation pathway signal Cag_1921 84 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 78188624 Nonpathogen - conserved hypothetical protein F56H9.1 Cag_0646 1 None None None 78188894 Nonpathogen - hypothetical protein Cag_0926 3 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 162319772 Common rpsO 30S ribosomal protein S15 Cag_1458 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 78188131 Common - hypothetical protein Cag_0148 81 COG1434 COG1434, Uncharacterized conserved protein Function unknown 78189420 Common - Riboflavin kinase / FAD synthetase Cag_1459 211 COG0196 RibF, FAD synthase Coenzyme metabolism 78189862 Common - ExbB/TolQ family protein Cag_1907 130 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 78188808 Common - hydrolase, alpha/beta hydrolase fold family Cag_0837 160 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 78188532 Common - hypothetical protein Cag_0554 24 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188261 Common - hypothetical protein Cag_0280 37 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 78188128 Common - DNA mismatch repair protein Cag_0145 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 78189411 Common - aspartate alpha-decarboxylase Cag_1450 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 78189652 Common - hypothetical protein Cag_1696 114 COG1262 COG1262, Uncharacterized conserved protein Function unknown 78188342 Common - putative signal transduction protein with Nacht domain Cag_0364 96 COG1262 COG1262, Uncharacterized conserved protein Function unknown 78188632 Common - hypothetical protein Cag_0654 6 None None None 78189155 Common - phytoene desaturase Cag_1188 25 COG3349 COG3349, Uncharacterized conserved protein Function unknown 78188257 Common - hypothetical protein Cag_0276 6 None None None 78189008 Common - hypothetical protein Cag_1041 14 None None None 78188332 Common rplA 50S ribosomal protein L1 Cag_0354 236 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 78189038 Common - heat shock protein 90 Cag_1071 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 78189021 Common - probable activation/secretion signal peptide protein Cag_1054 62 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 78188221 Common - dihydroflavonol 4-reductase family Cag_0240 128 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78189718 Common - site-specific recombinase, phage/XerD family Cag_1762 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 78189901 Nonpathogen - DsrM protein Cag_1948 20 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 78189128 Common - tyrosyl-tRNA synthetase Cag_1161 243 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78188672 Common - hypothetical protein Cag_0696 9 None None None 78189461 Nonpathogen - hypothetical protein Cag_1500 3 None None None 78188897 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol synthase Cag_0929 190 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 78188275 Common - hypothetical protein Cag_0294 62 COG3943 COG3943, Virulence protein General function prediction only 78189441 Common - Acetyltransferase (isoleucine patch superfamily)-like Cag_1480 83 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 78188615 Common - NADH dehydrogenase I, 49 kDa subunit Cag_0637 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 78189927 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Cag_1974 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 78189966 Common - thiol:disulfide interchange protein, thioredoxin family protein Cag_2013 152 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 78188915 Common - D-alanine-D-alanine ligase and related ATP-grasp enzyme-like Cag_0947 63 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 78189436 Common - glycosyl transferase Cag_1475 211 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78189711 Common - outer surface protein, putative Cag_1755 12 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 78189875 Common - sulfur oxidation protein SoxX Cag_1922 14 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 78189233 Common thiG thiazole synthase Cag_1267 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 78188617 Common - NADH dehydrogenase I, 23 kDa subunit Cag_0639 172 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 78189028 Common - conserved hypothetical phage AbiD protein Cag_1061 36 COG4823 AbiF, Abortive infection bacteriophage resistance protein Defense mechanisms 78189330 Nonpathogen - hypothetical protein Cag_1367 1 None None None 78188354 Common - hypothetical protein Cag_0376 2 None None None 78188963 Nonpathogen - hypothetical protein Cag_0995 1 None None None 78188869 Common - 5-formyltetrahydrofolate cyclo-ligase, putative Cag_0899 189 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 78189619 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Cag_1662 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 78188728 Common - FecCD transport family protein Cag_0754 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 78188268 Common - hypothetical protein Cag_0287 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 78189468 Common - transposase Cag_1507 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188976 Common - CRISPR-associated CT1134 family protein Cag_1009 32 None None None 78189559 Common - hypothetical protein Cag_1599 4 None None None 78189681 Common - Kup system potassium uptake protein Cag_1725 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 78188369 Common - Peptidase M41, FtsH Cag_0391 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 78188589 Nonpathogen - putative anti-sigma regulatory factor (serine/threonine protein kinase) Cag_0611 8 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 78188774 Common - 16S rRNA processing protein RimM Cag_0803 129 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 78189099 Common - acylneuraminate cytidylyltransferase Cag_1132 77 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 78188582 Nonpathogen - hypothetical protein Cag_0604 8 COG0392 COG0392, Predicted integral membrane protein Function unknown 78189196 Common - Molybdenum-pterin binding protein Cag_1230 96 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 78188097 Common - Elongator protein 3/MiaB/NifB Cag_0114 104 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 78188106 Common - AcrB/AcrD/AcrF family protein Cag_0123 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 78189659 Common - hypothetical protein Cag_1703 4 None None None 78189210 Common nifH nitrogenase reductase Cag_1244 75 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 78188309 Common - hypothetical protein Cag_0331 14 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 78188165 Common - Fic family protein Cag_0182 98 COG3177 COG3177, Uncharacterized conserved protein Function unknown 78188595 Nonpathogen - hypothetical protein Cag_0617 8 None None None 78188347 Common alaS alanyl-tRNA synthetase Cag_0369 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78189360 Nonpathogen - hypothetical protein Cag_1397 3 None None None 78188287 Common - hypothetical protein Cag_0308 7 None None None 78188559 Nonpathogen - hypothetical protein Cag_0581 1 None None None 78189001 Common - hypothetical protein Cag_1034 11 None None None 78188732 Common - hypothetical protein Cag_0759 47 COG1002 COG1002, Type II restriction enzyme, methylase subunits Defense mechanisms 78188016 Nonpathogen - hypothetical protein Cag_0032 3 None None None 78188319 Common - TPR repeat Cag_0341 64 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 78189577 Common - hypothetical protein Cag_1619 36 COG2944 COG2944, Predicted transcriptional regulator Transcription 78189207 Common - hypothetical protein Cag_1241 12 None None None 78189060 Common - putative exonuclease Cag_1093 89 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 78188456 Common - VpsC protein Cag_0478 28 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 78188938 Common - hypothetical protein Cag_0970 7 None None None 78188389 Common - transcriptional regulator, AraC family Cag_0411 81 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 78189281 Common - glycosyl transferase Cag_1316 148 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 78189823 Common - glycosyl transferase Cag_1868 132 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78189295 Common - Apolipoprotein N-acyltransferase Cag_1330 163 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 78188814 Common - hypothetical protein Cag_0844 20 COG4924 COG4924, Uncharacterized protein conserved in bacteria Function unknown 78189126 Common - L-aspartate oxidase Cag_1159 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 78188891 Common - amino acid permease Cag_0923 191 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 78188036 Common - Phospho-N-acetylmuramoyl-pentapeptide transferase Cag_0052 224 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 78189916 Common - hypothetical protein Cag_1963 40 COG0730 COG0730, Predicted permeases General function prediction only 78188270 Common - Acetyl-CoA carboxylase carboxyl transferase, beta subunit Cag_0289 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 78188604 Common - recombination factor protein RarA Cag_0626 240 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 78188597 Common - NrfC protein Cag_0619 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 78189622 Common - fatty acid/phospholipid synthesis protein Cag_1665 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 78189568 Common - DnaB helicase Cag_1608 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 78188100 Common - Anion-transporting ATPase Cag_0117 97 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 78188931 Common - polyprenyl synthetase Cag_0963 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 78189702 Common - MesJ protein Cag_1746 211 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 78188188 Common - bacterioferritin comigratory protein, thiol peroxidase, putative Cag_0205 229 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 78189141 Common - GTP-binding protein HflX Cag_1174 216 COG2262 HflX, GTPases General function prediction only 78188905 Common - Phosphoribosylformylglycinamidine synthase I Cag_0937 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 78188173 Common - cytosine deaminase, putative Cag_0190 210 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 78188754 Common hslU ATP-dependent protease ATP-binding subunit Cag_0783 210 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 78188312 Common - ATPase Cag_0334 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 78189959 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Cag_2006 193 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 78188870 Common - polyphosphate kinase Cag_0900 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 78189738 Common - MECDP-synthase Cag_1782 188 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 78188215 Common - Nicotinate-nucleotide pyrophosphorylase Cag_0234 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 78188186 Common - hypothetical protein Cag_0203 117 COG0628 PerM, Predicted permease General function prediction only 78188228 Common - hypothetical protein Cag_0247 100 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 78188806 Nonpathogen - hypothetical protein Cag_0835 1 None None None 78189629 Common - O-succinylbenzoate-CoA ligase Cag_1672 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 78188405 Nonpathogen - hypothetical protein Cag_0427 2 None None None 78188071 Common - Iojap-related protein Cag_0087 198 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 78189908 Common - Sulfite reductase, dissimilatory-type beta subunit Cag_1955 34 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 78188733 Common - DEAD/DEAH box helicase-like Cag_0760 16 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 78188374 Nonpathogen - hypothetical protein Cag_0396 1 None None None 78188726 Common - Ribonuclease R Cag_0752 192 COG0557 VacB, Exoribonuclease R Transcription 78188985 Common secA preprotein translocase subunit SecA Cag_1018 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 78189480 Common - delta-aminolevulinic acid dehydratase Cag_1520 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 78188925 Common - hypothetical protein Cag_0957 23 COG3668 ParE, Plasmid stabilization system protein General function prediction only 78189377 Common - Protein of unknown function 661 Cag_1414 24 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 78189374 Common - enoyl-(acyl-carrier protein) reductase (NADH) Cag_1411 201 COG0623 FabI, Enoyl- acyl-carrier-protein 78187993 Common - Peptidase M50, putative membrane-associated zinc metallopeptidase Cag_0009 213 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 78189764 Common - Glycogen/starch synthase, ADP-glucose type Cag_1808 126 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 78188062 Common - Elongator protein 3/MiaB/NifB Cag_0078 171 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 78189086 Common - Fmu, rRNA SAM-dependent methyltransferase Cag_1119 212 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 78189259 Common - glycosyl transferase Cag_1294 229 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78188707 Common - Adenylylsulfate kinase Cag_0731 143 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 78189267 Common - ATPase-like Cag_1302 34 COG4637 COG4637, Predicted ATPase General function prediction only 78189684 Common - pentapeptide repeat family protein Cag_1728 87 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 78188941 Common - transcriptional regulator, putative Cag_0973 21 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 78189985 Common rnpA ribonuclease P Cag_2032 5 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 78188069 Common - conserved hypothetical protein, phage-related Cag_0085 32 COG4679 COG4679, Phage-related protein Function unknown 78189316 Common - purine nucleoside phosphorylase Cag_1351 145 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 78188154 Common - Phosphoribosylglycinamide synthetase Cag_0171 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 78189247 Common - Membrane-bound metallopeptidase-like Cag_1281 173 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 78189344 Common - alpha-amylase family protein Cag_1381 50 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 78189788 Common rplO 50S ribosomal protein L15 Cag_1832 171 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 78188879 Common - hypothetical protein Cag_0909 8 COG3668 ParE, Plasmid stabilization system protein General function prediction only 78189454 Common - hypothetical protein Cag_1493 149 COG1959 COG1959, Predicted transcriptional regulator Transcription 78189503 Nonpathogen - hypothetical protein Cag_1543 3 None None None 78188445 Common - KpsF/GutQ Cag_0467 167 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 78188304 Common - Ribosome recycling factor Cag_0326 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 78189130 Common - oxidoreductase, FAD-binding Cag_1163 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 78188646 Common - Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)-like Cag_0668 67 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 78189541 Common - Magnesium and cobalt transport protein CorA Cag_1581 179 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 78189846 Common - putative transcriptional regulator, ArsR family Cag_1891 115 COG0640 ArsR, Predicted transcriptional regulators Transcription 78188649 Common - UDP-glucose 4-epimerase Cag_0671 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78188054 Common argS arginyl-tRNA synthetase Cag_0070 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78188669 Common - sepiapterin reductase Cag_0693 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 78189852 Common - Nidogen, extracellular region Cag_1897 71 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 78188507 Common - hypothetical protein Cag_0529 136 None None None 78189753 Nonpathogen - hypothetical protein Cag_1797 2 None None None 78189135 Common - quinolinate synthetase Cag_1168 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 78189250 Nonpathogen - hypothetical protein Cag_1284 1 None None None 78189403 Common - hypothetical protein Cag_1441 108 COG3177 COG3177, Uncharacterized conserved protein Function unknown 78187987 Common - RecF protein Cag_0003 163 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 78189804 Common rplB 50S ribosomal protein L2 Cag_1848 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 78189670 Common infC translation initiation factor IF-3 Cag_1714 208 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 78188742 Nonpathogen - hypothetical protein Cag_0771 1 None None None 78188291 Common - hypothetical protein Cag_0312 6 COG2886 COG2886, Uncharacterized small protein Function unknown 78189778 Common gidB glucose-inhibited division protein B Cag_1822 116 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 78189728 Common - hypothetical protein Cag_1772 20 COG4637 COG4637, Predicted ATPase General function prediction only 78189816 Common - hypothetical protein Cag_1861 3 None None None 78189479 Common - chorismate synthase Cag_1519 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 78189527 Common - hydrogenase/sulfur reductase, gamma subunit Cag_1567 72 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 78188246 Common - hypothetical protein Cag_0265 14 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 78188761 Common - hypothetical protein Cag_0790 7 None None None 78189234 Common thiH thiamine biosynthesis protein ThiH Cag_1268 54 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 78188652 Nonpathogen - hypothetical protein Cag_0674 1 None None None 78188699 Common - oxidoreductase, Gfo/Idh/MocA family Cag_0723 170 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 78189041 Common - xanthine/uracil permease family protein Cag_1074 135 COG2252 COG2252, Permeases General function prediction only 78189614 Common - beta-N-acetylglucosaminidase Cag_1657 184 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 78189102 Common - long-chain fatty-acid-CoA ligase Cag_1135 219 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 78189325 Common - hypothetical protein Cag_1360 5 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 78188045 Common - Protein of unknown function DUF152 Cag_0061 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 78188416 Common - hypothetical protein Cag_0438 15 COG3339 COG3339, Uncharacterized conserved protein Function unknown 78188424 Common - hypothetical protein Cag_0446 9 None None None 78188245 Common - ATPase Cag_0264 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 78188689 Common - hypothetical protein Cag_0713 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 78189607 Common rplM 50S ribosomal protein L13 Cag_1650 237 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 78189308 Common - hypothetical protein Cag_1343 6 None None None 78187998 Common - Holliday junction resolvase YqgF Cag_0014 144 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 78188570 Common - DedA family Cag_0592 163 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 78188081 Common - YgfB and YecA Cag_0098 26 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 78189173 Common - Homoserine O-acetyltransferase Cag_1206 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 78188836 Nonpathogen - hypothetical protein Cag_0866 1 None None None 78188460 Common - Bacitracin resistance protein BacA Cag_0482 193 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 78189088 Common - hypothetical protein Cag_1121 31 None None None 78188352 Nonpathogen - hypothetical protein Cag_0374 3 None None None 78189110 Common - Cation efflux protein Cag_1143 204 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 78189466 Nonpathogen - hypothetical protein Cag_1505 2 None None None 78189546 Common - Adenylylsulfate reductase, beta subunit Cag_1586 17 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 78189226 Nonpathogen - transcriptional regulator, XRE family Cag_1260 1 COG1396 HipB, Predicted transcriptional regulators Transcription 78189031 Common - Molybdopterin binding domain Cag_1064 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 78188717 Common - metalloprotease secretion protein Cag_0743 114 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 78189646 Common - polynucleotide phosphorylase/polyadenylase Cag_1689 238 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 78189522 Common - hypothetical protein Cag_1562 50 COG4804 COG4804, Uncharacterized conserved protein Function unknown 78189495 Nonpathogen - hypothetical protein Cag_1535 1 None None None 78188789 Nonpathogen - hypothetical protein Cag_0818 1 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 78189249 Common - hypothetical protein Cag_1283 16 COG1433 COG1433, Uncharacterized conserved protein Function unknown 78188339 Common - Elongation factor P Cag_0361 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 78189762 Common - Putative oxygen-independent coproporphyrinogen III oxidase Cag_1806 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 78189781 Common rpsD 30S ribosomal protein S4 Cag_1825 245 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 78188862 Common - internalin-related protein Cag_0892 30 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 78189786 Common - Peptidase M24A, methionine aminopeptidase, subfamily 1 Cag_1830 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 78189601 Nonpathogen - 2-vinyl bacteriochlorophyllide hydratase Cag_1644 14 None None None 78189631 Common - adhesion protein, putative Cag_1674 140 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 78188140 Common - zinc transporter ZupT Cag_0157 106 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 78188373 Common - cytochrome b-c complex, cytochrome b subunit Cag_0395 148 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 78188960 Nonpathogen - hypothetical protein Cag_0992 1 None None None 78189818 Common - glycosyl transferase, group 1 family protein Cag_1863 47 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78189054 Common - SpoU rRNA methylase family protein Cag_1087 208 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 78188251 Common - hypothetical protein Cag_0270 20 None None None 78189666 Common - NADH-dependent butanol dehydrogenase Cag_1710 173 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 78189117 Common - Thioredoxin Cag_1150 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 78188482 Common - Phosphoribosylglycinamide formyltransferase Cag_0504 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 78188518 Common - Phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Cag_0540 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 78189953 Common - transcriptional regulator, Fis family Cag_2000 169 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 78188489 Common - metal dependent phosphohydrolase Cag_0511 87 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 78188765 Common - hypothetical protein Cag_0794 71 COG2119 COG2119, Predicted membrane protein Function unknown 78188325 Common - Enolase Cag_0347 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 78188679 Common - ribonucleotide-diphosphate reductase subunit alpha Cag_0703 144 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 78188666 Nonpathogen - hypothetical protein Cag_0690 3 None None None 78189844 Common - RNA polymerase sigma factor RpoE Cag_1889 174 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 78188843 Common - TPR repeat Cag_0873 20 None None None 78189387 Common - Negative regulator of class I heat shock protein Cag_1424 149 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 78188110 Common - Succinate dehydrogenase or fumarate reductase, flavoprotein subunit Cag_0127 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 78189693 Common - hypothetical protein Cag_1737 7 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 78188439 Common - electron transfer flavoprotein alpha-subunit Cag_0461 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 78188208 Common - NAD-dependent epimerase/dehydratase family protein/3-beta hydroxysteroid dehydrogenase/isomerase family protein Cag_0225 182 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 78188359 Common - transcriptional regulator, XRE family Cag_0381 15 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 78189320 Common - Initiation factor 2B alpha/beta/delta Cag_1355 129 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 78189380 Common - hypothetical protein Cag_1417 127 COG0432 COG0432, Uncharacterized conserved protein Function unknown 78188007 Common - Peptide chain release factor 2 Cag_0023 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 78187989 Common - Glucosamine-fructose-6-phosphate aminotransferase, isomerising Cag_0005 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 78188780 Common - probable transposase Cag_0809 14 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 78188197 Common - putative cold-shock DNA-binding domain protein Cag_0214 179 COG1278 CspC, Cold shock proteins Transcription 78189273 Nonpathogen - hypothetical protein Cag_1308 14 None None None 78189565 Common - hypothetical protein Cag_1605 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 78189654 Common - Outer membrane protein and related peptidoglycan-associated (lipo)proteins-like Cag_1698 155 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 78188346 Common - hypothetical protein Cag_0368 14 None None None 78188771 Nonpathogen - hypothetical protein Cag_0800 3 None None None 78189096 Nonpathogen - hypothetical protein Cag_1129 2 None None None 78188917 Common - D-alanine-D-alanine ligase and related ATP-grasp enzyme-like Cag_0949 76 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 78189889 Common - hypothetical protein Cag_1936 112 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 78189429 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Cag_1468 133 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 78188491 Common - putative DNA-binding protein Cag_0513 64 COG3943 COG3943, Virulence protein General function prediction only 78189858 Common - Acetolactate synthase, small subunit Cag_1903 191 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 78188606 Common - hypothetical protein Cag_0628 27 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 78188498 Common - hypothetical protein Cag_0520 13 None None None 78188099 Common - Elongator protein 3/MiaB/NifB Cag_0116 90 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 78188995 Common - heterodisulfide reductase, subunit C/succinate dehydrogenase, subunit C Cag_1028 57 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 78188613 Common - NADH dehydrogenase (ubiquinone), 20 kDa subunit Cag_0635 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 78189929 Nonpathogen - hypothetical protein Cag_1976 1 None None None 78189608 Common engA GTP-binding protein EngA Cag_1651 227 COG1160 COG1160, Predicted GTPases General function prediction only 78188167 Nonpathogen - hypothetical protein Cag_0184 3 None None None 78188919 Common - hypothetical protein Cag_0951 22 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 78189745 Common - serine hydroxymethyltransferase Cag_1789 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 78189063 Common - gamma-glutamyl kinase Cag_1096 191 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 78189212 Common - nitrogen regulatory protein P-II (GlnB, GlnK) Cag_1246 181 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 78189868 Nonpathogen - hypothetical protein Cag_1913 1 None None None 78188039 Common - N-acetylglucosaminyltransferase, MurG Cag_0055 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 78189922 Common - Recombination protein O, RecO Cag_1969 46 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 78188927 Common - Heavy metal translocating P-type ATPase Cag_0959 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 78188851 Nonpathogen - hypothetical protein Cag_0881 3 None None None 78189580 Common - Pseudouridine synthase, RluD Cag_1622 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 78188367 Common - Peptidase S14, ClpP Cag_0389 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 78188710 Nonpathogen - hypothetical protein Cag_0734 1 None None None 78189944 Common - Peptidase S41A, C-terminal protease Cag_1991 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 78188200 Common - Anion-transporting ATPase Cag_0217 93 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 78189937 Common - Alpha amylase, catalytic subdomain Cag_1984 91 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 78189018 Common - hypothetical protein Cag_1051 4 COG3668 ParE, Plasmid stabilization system protein General function prediction only 78188469 Common - Peptidase S26A, signal peptidase I Cag_0491 194 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 78189351 Nonpathogen - hypothetical protein Cag_1388 1 None None None 78188074 Common - hypothetical protein Cag_0091 33 COG0824 FcbC, Predicted thioesterase General function prediction only 78189044 Common - hypothetical protein Cag_1077 23 COG5611 COG5611, Predicted nucleic-acid-binding protein, contains PIN domain General function prediction only 78188121 Common - threonine synthase Cag_0138 198 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 78189589 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Cag_1631 230 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 78188210 Common - Magnesium-chelatase, subunit H Cag_0227 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 78189107 Nonpathogen - hypothetical protein Cag_1140 5 None None None 78189392 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Cag_1430 166 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 78189539 Common - hypothetical protein Cag_1579 2 None None None 78188565 Nonpathogen - hypothetical protein Cag_0587 4 None None None 78189709 Common - hypothetical protein Cag_1753 118 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 78188240 Common - 3-oxoacyl-(acyl-carrier-protein) reductase, putative Cag_0259 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 78188360 Common - thiamine biosynthesis protein ThiC Cag_0382 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 78188133 Common - hypothetical protein Cag_0150 33 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 78189865 Common - TolB protein, putative Cag_1910 168 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 78188990 Nonpathogen - Glycosyltransferase-like Cag_1023 7 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 78189639 Common - hypothetical protein Cag_1682 6 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 78189186 Common - 3-dehydroquinate synthase Cag_1219 206 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 78188334 Common rplL 50S ribosomal protein L7/L12 Cag_0356 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 78189698 Common - bacteriochlorophyll/chlorophyll a synthase Cag_1742 65 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 78189034 Common - hypothetical protein Cag_1067 18 None None None 78189981 Common - 23S rRNA methyltransferase/RumA Cag_2028 198 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 78188272 Common - Survival protein SurE Cag_0291 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 78188034 Common - UDP-N-acetylmuramyl-tripeptide synthetase Cag_0050 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 78188541 Common - putative PAS/PAC sensor protein Cag_0563 161 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 78188739 Common - possible abortive infection phage resistance protein Cag_0767 41 None None None 78189798 Common rpsQ 30S ribosomal protein S17 Cag_1842 229 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 78189957 Common - sulfide dehydrogenase, flavoprotein subunit Cag_2004 118 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 78188174 Nonpathogen - chlorosome envelope protein B Cag_0191 3 None None None 78188139 Common - ABC transporter, permease protein Cag_0156 108 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 78188634 Common - nucleic acid-binding protein, containing PIN domain Cag_0656 21 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78189446 Nonpathogen - hypothetical protein Cag_1485 3 None None None 78189597 Common - ribulose-bisphosphate carboxylase large chain Cag_1640 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 78189157 Common - hypothetical protein Cag_1190 185 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 78189416 Nonpathogen - hypothetical protein Cag_1455 3 None None None 78188447 Common - polysaccharide biosynthesis protein Cag_0469 30 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 78189011 Common - hypothetical protein Cag_1044 24 COG3784 COG3784, Uncharacterized protein conserved in bacteria Function unknown 78188548 Common rpsA 30S ribosomal protein S1 Cag_0570 222 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 78189356 Common - Maf-like protein Cag_1393 184 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 78188184 Common - hypothetical protein Cag_0201 201 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 78188059 Common - DNA topoisomerase I Cag_0075 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 78189134 Common - chaperonin, 10 kDa Cag_1167 22 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 78189964 Common - hypothetical protein Cag_2011 38 COG3360 COG3360, Uncharacterized conserved protein Function unknown 78188779 Common - specificity determinant HsdS-like Cag_0808 75 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 78188340 Common - Histone-like DNA-binding protein Cag_0362 213 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 78188965 Common - hypothetical protein Cag_0998 6 None None None 78188804 Nonpathogen - hypothetical protein Cag_0833 1 None None None 78188580 Common - fructose-1,6-bisphosphatase Cag_0602 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 78188948 Common - hypothetical protein Cag_0980 103 COG3177 COG3177, Uncharacterized conserved protein Function unknown 78188407 Common - transcriptional modulator of MazE/toxin, MazF Cag_0429 47 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 78189139 Common - chlorosome envelope protein I Cag_1172 23 COG0633 Fdx, Ferredoxin Energy production and conversion 78188383 Common - hypothetical protein Cag_0405 14 None None None 78188907 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Cag_0939 149 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 78188052 Common - putative lipoprotein Cag_0068 9 COG4105 ComL, DNA uptake lipoprotein General function prediction only 78188601 Common - Riboflavin biosynthesis protein RibD Cag_0623 233 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 78188658 Common - hypothetical protein Cag_0681 7 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78189663 Common - Pantoate-beta-alanine ligase Cag_1707 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 78189808 Common rpsJ 30S ribosomal protein S10 Cag_1852 246 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 78189379 Common - Alpha amylase, catalytic subdomain Cag_1416 36 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 78189078 Common - hypothetical protein Cag_1111 47 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 78188598 Common - Twin-arginine translocation pathway signal Cag_0620 188 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 78188428 Nonpathogen - hypothetical protein Cag_0450 5 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 78187995 Nonpathogen - hypothetical protein Cag_0011 3 None None None 78188723 Common - hypothetical protein Cag_0749 12 COG4627 COG4627, Uncharacterized protein conserved in bacteria Function unknown 78188047 Nonpathogen - hypothetical protein Cag_0063 3 None None None 78188198 Nonpathogen - hypothetical protein Cag_0215 11 None None None 78189828 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Cag_1873 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 78188547 Common era GTP-binding protein Era Cag_0569 220 COG1159 Era, GTPase General function prediction only 78189801 Common rpsC 30S ribosomal protein S3 Cag_1845 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 78189313 Common - TPR repeat Cag_1348 9 None None None 78188687 Common - prolyl-tRNA synthetase Cag_0711 230 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 78189245 Common nadE NAD synthetase Cag_1279 233 COG0171 NadE, NAD synthase Coenzyme metabolism 78188156 Common - carbamoyl-phosphate synthase, medium subunit Cag_0173 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 78189755 Nonpathogen - hypothetical protein Cag_1799 2 None None None 78188191 Common - tRNA-i(6)A37 modification enzyme MiaB Cag_0208 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 78189448 Common - putative plasmid maintenance system antidote protein, XRE family Cag_1487 77 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 78188841 Common - Secretion protein HlyD Cag_0871 114 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 78188936 Common - hypothetical protein Cag_0968 8 None None None 78189208 Common - VCBS Cag_1242 179 None None None 78188496 Common - Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Cag_0518 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 78189231 Common - putative membrane-located cell surface saccharide saccharide acetylase protein Cag_1265 120 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 78188877 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase Cag_0907 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 78189891 Common - Sel1-like repeat Cag_1938 121 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 78188328 Common - oxidoreductase, short-chain dehydrogenase/reductase family Cag_0350 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 78188812 Common - hypothetical protein Cag_0841 13 None None None 78188026 Common - hypothetical protein Cag_0042 13 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 78188279 Common - Glutamine amidotransferase of anthranilate synthase Cag_0298 238 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 78189696 Common - aminopeptidase P Cag_1740 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 78188243 Nonpathogen - hypothetical protein Cag_0262 3 None None None 78188828 Nonpathogen - hypothetical protein Cag_0858 2 None None None 78189201 Common - hypothetical protein Cag_1235 112 None None None 78189370 Common - peptidase, M50 family Cag_1407 31 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 78188555 Nonpathogen - hypothetical protein Cag_0577 2 None None None 78188293 Nonpathogen - hypothetical protein Cag_0315 1 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 78189549 Common - putative transcriptional regulator, AsnC family Cag_1589 157 COG1522 Lrp, Transcriptional regulators Transcription 78189339 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Cag_1376 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 78188109 Common - CBS Cag_0126 90 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 78189452 Common - TPR repeat Cag_1491 30 None None None 78189668 Common rplT 50S ribosomal protein L20 Cag_1712 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 78189704 Common - Twin-arginine translocation protein TatA/E Cag_1748 24 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 78189489 Common - hypothetical protein Cag_1529 13 None None None 162319774 Common - ferredoxin--NADP(+) reductase subunit alpha Cag_0538 96 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 78189935 Common - putative ferric uptake regulator, FUR family Cag_1982 189 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 78189637 Common - Delta 1-pyrroline-5-carboxylate reductase Cag_1680 215 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 78188102 Nonpathogen - hypothetical protein Cag_0119 3 None None None 78189046 Common - ATPase Cag_1079 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 78188591 Common - SapC-related protein Cag_0613 26 None None None 78189806 Common rplD 50S ribosomal protein L4 Cag_1850 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 78189252 Common - bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase Cag_1286 223 COG1049 AcnB, Aconitase B Energy production and conversion 78189575 Common - hypothetical protein Cag_1617 92 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 78188430 Common - fic family protein Cag_0452 44 COG3177 COG3177, Uncharacterized conserved protein Function unknown 78188018 Common - hypothetical protein Cag_0034 14 None None None 78188694 Common - hypothetical protein Cag_0718 2 None None None 78189166 Common - hypothetical protein Cag_1199 20 COG2253 COG2253, Uncharacterized conserved protein Function unknown 78188426 Common - DegT/DnrJ/EryC1/StrS family protein Cag_0448 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 78189025 Common - nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Cag_1058 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 78189275 Common - HNH nuclease Cag_1310 4 COG1403 McrA, Restriction endonuclease Defense mechanisms 78189644 Common - hypothetical protein Cag_1687 4 None None None 78188576 Common - hypothetical protein Cag_0598 61 COG3943 COG3943, Virulence protein General function prediction only 78189215 Common - Nitrogenase MoFe cofactor biosynthesis protein NifE Cag_1249 56 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 78188896 Common - S-adenosylmethionine:tRNA ribosyltransferase-isomerase Cag_0928 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 78189171 Common - Secretion protein HlyD Cag_1204 159 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 78189306 Common - Excinuclease ABC, C subunit Cag_1341 224 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 78189771 Common - light-independent protochlorophyllide reductase subunit N Cag_1815 27 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 78189283 Nonpathogen - hypothetical protein Cag_1318 1 None None None 78188797 Nonpathogen - hypothetical protein Cag_0826 3 None None None 78188298 Common - 3-deoxy-manno-octulosonate cytidylyltransferase Cag_0320 148 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 78189363 Common - chloride channel, putative Cag_1400 159 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 78189835 Nonpathogen - hypothetical protein Cag_1880 1 None None None 78189318 Nonpathogen - hypothetical protein Cag_1353 1 None None None 78189851 Nonpathogen - hypothetical protein Cag_1896 1 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 78188651 Common - putative glycosyltransferase Cag_0673 8 None None None 78188705 Common - Peptidase S41A, C-terminal protease Cag_0729 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 78189477 Common - HemX protein, putative Cag_1517 13 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 78188644 Common - hypothetical protein Cag_0666 36 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 78189260 Common - MCBG protein (microcin resistance protein)-like Cag_1295 41 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 78188511 Common - Hydrogenase maturation protein HypF Cag_0533 112 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 78188262 Common - hypothetical protein Cag_0281 53 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 78189776 Nonpathogen - hypothetical protein Cag_1820 6 None None None 78189269 Nonpathogen - hypothetical protein Cag_1304 3 None None None 78188953 Nonpathogen - putative plasmid maintenance system antidote protein, XRE family Cag_0985 1 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 78189731 Common - metal dependent phosphohydrolase Cag_1775 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 78189405 Common - ATPase Cag_1444 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 78189505 Common - NUDIX/MutT family protein Cag_1545 28 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 78188889 Common - diguanylate cyclase (GGDEF domain) Cag_0921 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 78188524 Common - hypothetical protein Cag_0546 8 None None None 78188226 Common - hydrogenase/sulfur reductase, alpha subunit Cag_0245 109 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 78188478 Common - Phosphate ABC transporter, permease protein PstC Cag_0500 226 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 78188142 Nonpathogen - hypothetical protein Cag_0159 10 None None None 78188217 Common - putative plasmid maintenance system antidote protein, XRE family Cag_0236 19 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 78188393 Common - Molybdate ABC transporter, ATP-binding protein Cag_0415 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 78189293 Common - transcriptional regulator, MerR family Cag_1328 87 COG0789 SoxR, Predicted transcriptional regulators Transcription 78189239 Common - hypothetical protein Cag_1273 48 COG2153 ElaA, Predicted acyltransferase General function prediction only 78188744 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Cag_0773 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 78189550 Common - zeta-carotene desaturase Cag_1590 63 COG3349 COG3349, Uncharacterized conserved protein Function unknown 78189721 Common - peptide ABC transporter, periplasmic peptide-binding protein Cag_1765 187 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 78189179 Common - Cell division transporter substrate-binding protein FtsY Cag_1212 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 78188980 Common - nitroreductase family protein Cag_1013 109 COG0778 NfnB, Nitroreductase Energy production and conversion 78189643 Common - hypothetical protein Cag_1686 3 None None None