Pseudomonas fluorescens PfO-1, complete genome NC_007492 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 77457240 Common - hypothetical protein Pfl_1013 9 None None None 77459823 Common - NolW-like Pfl_3601 11 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 77461101 Common - GntR-like Pfl_4880 109 COG1802 GntR, Transcriptional regulators Transcription 77457002 Common tpiA triosephosphate isomerase Pfl_0775 221 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 77459540 Common - TonB-dependent siderophore receptor Pfl_3318 119 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 77459731 Common - hypothetical protein Pfl_3509 2 COG5455 COG5455, Predicted integral membrane protein Function unknown 77456534 Common - hypothetical protein Pfl_0306 29 COG2944 COG2944, Predicted transcriptional regulator Transcription 77456862 Common - lipoprotein, putative Pfl_0634 2 None None None 77457209 Common - Glutaredoxin Pfl_0982 50 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 77458895 Common - phosphoglucomutase Pfl_2670 184 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 77460027 Common - hypothetical protein Pfl_3805 3 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77460490 Common - Guanylate kinase/L-type calcium channel region Pfl_4269 39 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 77458050 Common - Cytochrome c oxidase cbb3-type, subunit I Pfl_1823 144 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 77457235 Common - ErfK/YbiS/YcfS/YnhG Pfl_1008 54 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 77461104 Common - Carbon starvation protein CstA Pfl_4883 106 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 77457991 Common prpB 2-methylisocitrate lyase Pfl_1764 122 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 77461913 Common - Putative Adenylate/Guanylate Cyclase Pfl_5693 25 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 77461861 Common - Transcriptional Regulator, LysR family Pfl_5641 192 COG0583 LysR, Transcriptional regulator Transcription 77459280 Common - Transcriptional Regulator, TetR family Pfl_3058 100 COG1309 AcrR, Transcriptional regulator Transcription 77456294 Common - Binding-protein-dependent transport systems inner membrane component Pfl_0066 113 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 77456479 Common - xenobiotic compound monooxygenase, DszA family, A subunit Pfl_0251 75 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 77460562 Common - hypothetical protein Pfl_4341 3 None None None 77460020 Common - TonB-dependent siderophore receptor Pfl_3798 87 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77457344 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha Pfl_1117 183 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 77456683 Common - hypothetical protein Pfl_0455 2 None None None 77461301 Common rpsJ 30S ribosomal protein S10 Pfl_5080 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 77456278 Common - Putative diguanylate cyclase Pfl_0050 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77460380 Common - fatty acid/phospholipid synthesis protein Pfl_4159 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 77461495 Common - hypothetical protein Pfl_5274 37 COG3686 COG3686, Predicted membrane protein Function unknown 77456358 Common - hypothetical protein Pfl_0130 33 COG3672 COG3672, Predicted periplasmic protein Function unknown 77460537 Nonpathogen - hypothetical protein Pfl_4316 1 None None None 77458660 Common - ThiJ/PfpI Pfl_2435 86 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 77458352 Common - Transcriptional Regulator, XRE family with Cupin sensor domain Pfl_2125 61 COG1396 HipB, Predicted transcriptional regulators Transcription 77458648 Nonpathogen - hypothetical protein Pfl_2423 1 None None None 77460971 Common - hypothetical protein Pfl_4750 136 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 77461592 Common - Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase Pfl_5371 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 77459050 Common - Glycoside hydrolase, family 16 Pfl_2825 43 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 77456870 Common - hypothetical protein Pfl_0642 1 None None None 77457399 Common - Pyocin R2_PP, lytic enzyme Pfl_1172 30 COG3179 COG3179, Predicted chitinase General function prediction only 77458323 Common - Methyltransferase small Pfl_2096 35 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 77456619 Common - Transcriptional Regulator, TetR family Pfl_0391 55 COG1309 AcrR, Transcriptional regulator Transcription 77457553 Common - Protein of unknown function DUF450 Pfl_1326 38 COG4748 COG4748, Uncharacterized conserved protein Function unknown 77459444 Common - hypothetical protein Pfl_3222 61 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 77461116 Common - DJ-1 Pfl_4895 89 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 77457293 Common - OmpA/MotB Pfl_1066 171 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77457799 Common - CheW protein Pfl_1572 138 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77458844 Common - threonine dehydratase Pfl_2619 216 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 77460647 Common - Glutathione S-transferase-like Pfl_4426 63 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77459582 Nonpathogen - hypothetical protein Pfl_3360 1 None None None 77459706 Nonpathogen - hypothetical protein Pfl_3484 1 None None None 77460452 Common - hypothetical protein Pfl_4231 74 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 77457528 Common - hypothetical protein Pfl_1301 32 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 77459568 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_3346 213 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 77460546 Common - Short-chain dehydrogenase/reductase SDR Pfl_4325 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 77459114 Common - HvnB; halovibrin Pfl_2889 5 None None None 77460344 Common - Mandelate racemase/muconate lactonizing enzyme Pfl_4123 123 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 77456662 Common - hypothetical protein Pfl_0434 43 COG4261 COG4261, Predicted acyltransferase General function prediction only 77460147 Common - hypothetical protein Pfl_3926 6 None None None 77460085 Common - General substrate transporter Pfl_3864 126 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461652 Common - 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase Pfl_5431 134 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 77461797 Common - Protein serine/threonine phosphatase Pfl_5576 134 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 77461459 Common - Substrate-binding region of ABC-type glycine betaine transport system Pfl_5238 59 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 77458293 Common - Phospholipase/Carboxylesterase Pfl_2066 121 COG0400 COG0400, Predicted esterase General function prediction only 77459783 Common - GCN5-related N-acetyltransferase Pfl_3561 54 COG0456 RimI, Acetyltransferases General function prediction only 77459589 Common - hypothetical protein Pfl_3367 2 None None None 77461461 Common - Glycine betaine/L-proline transport ATP-binding subunit Pfl_5240 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 77458127 Common - Argininosuccinate synthase Pfl_1900 1 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 77459086 Common - Cytochrome P450n Pfl_2861 89 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 77460161 Common - peptide synthase Pfl_3940 224 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77459844 Common - Secretion protein HlyD Pfl_3622 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77457804 Common - Heme exporter protein CcmA Pfl_1577 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 77461951 Common - F0F1 ATP synthase subunit B Pfl_5734 123 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 77461868 Common - Sodium/hydrogen exchanger Pfl_5648 208 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 77458778 Common - Protein of unknown function DUF411 Pfl_2553 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 77458784 Common - hypothetical protein Pfl_2559 19 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 77458906 Common - Type I secretion membrane fusion protein, HlyD Pfl_2681 113 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77459723 Common - hypothetical protein Pfl_3501 2 None None None 77456402 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_0174 107 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77459287 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Pfl_3065 196 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 77458701 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_2476 199 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77461432 Common - short chain dehydrogenase Pfl_5211 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77458174 Common - hypothetical protein Pfl_1947 24 COG3541 COG3541, Predicted nucleotidyltransferase General function prediction only 77460913 Common - Ubiquinol-cytochrome c reductase, iron-sulfur subunit Pfl_4692 95 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 77461512 Common - Transcriptional Regulator, LysR family Pfl_5291 159 COG0583 LysR, Transcriptional regulator Transcription 77461444 Common - NADH:flavin oxidoreductase/NADH oxidase Pfl_5223 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77459919 Common clpP ATP-dependent Clp protease proteolytic subunit Pfl_3697 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 77458418 Common - hypothetical protein Pfl_2191 1 None None None 77461756 Common - Protein of unknown function DUF861 Pfl_5535 27 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 77458709 Common - Secretion protein HlyD Pfl_2484 58 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77459596 Nonpathogen - hypothetical protein Pfl_3374 1 None None None 77461787 Common - hypothetical protein Pfl_5566 1 None None None 77460806 Common - Twin-arginine translocation pathway signal Pfl_4585 129 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 77457624 Common - hypothetical protein Pfl_1397 34 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 77461243 Common - hypothetical protein Pfl_5022 28 COG3897 COG3897, Predicted methyltransferase General function prediction only 77460476 Common - Anti-Sigma-28 factor, FlgM Pfl_4255 17 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 77461637 Common - Peroxidase Pfl_5416 211 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77461401 Common - predicted kinase Pfl_5180 54 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 77459618 Common - Aromatic amino acid permease Pfl_3396 36 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 77461158 Common - Cation efflux protein Pfl_4937 213 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 77458879 Common - hypothetical protein Pfl_2654 8 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 77461689 Common - isoprenoid biosynthesis protein with amidotransferase-like domain Pfl_5468 43 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 77460757 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_4536 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77460353 Nonpathogen - hypothetical protein Pfl_4132 1 None None None 77458281 Common - Arginine N-succinyltransferase beta subunit Pfl_2054 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 77457114 Common - Thioredoxin reductase Pfl_0887 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 77460140 Common - Antibiotic biosynthesis monooxygenase Pfl_3919 2 None None None 77458409 Common - extracellular solute-binding protein, family 5 Pfl_2182 167 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 77458014 Common - Ribosome modulation factor Pfl_1787 21 COG3130 Rmf, Ribosome modulation factor Translation, ribosomal structure and biogenesis 77458841 Common - GCN5-related N-acetyltransferase Pfl_2616 111 COG0456 RimI, Acetyltransferases General function prediction only 77457563 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_1336 179 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77458315 Nonpathogen - hypothetical protein Pfl_2088 1 None None None 77461843 Common - Phosphoribosylaminoimidazole carboxylase Pfl_5622 231 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 77458147 Common - ABC transporter-like Pfl_1920 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 77460441 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_4220 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77458564 Common - Binding-protein-dependent transport systems inner membrane component Pfl_2337 100 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 77461622 Common - Binding-protein-dependent transport systems inner membrane component Pfl_5401 182 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 77458276 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_2049 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77458080 Common - Peptidase M19, renal dipeptidase Pfl_1853 92 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 77459490 Common - Protein of unknown function DUF1028 Pfl_3268 40 COG3342 COG3342, Uncharacterized conserved protein Function unknown 77457257 Common - Response regulator receiver domain protein (CheY) Pfl_1030 6 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77459476 Common - Two Component Transcriptional Regulator, LuxR family Pfl_3254 175 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77458059 Nonpathogen - hypothetical protein Pfl_1832 1 None None None 77456567 Common - Nitrogen Metabolism Transcriptional Regulator, NtrC, Fis Family Pfl_0339 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77458365 Common - Secretion protein HlyD Pfl_2138 102 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77457273 Common - Binding-protein-dependent transport systems inner membrane component Pfl_1046 200 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 77459676 Common - TRAP dicarboxylate transporter- DctP subunit Pfl_3454 111 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 77457726 Common phhA phenylalanine 4-monooxygenase Pfl_1499 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 77460267 Common - DegT/DnrJ/EryC1/StrS aminotransferase Pfl_4046 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 77458423 Common - Metallophosphoesterase Pfl_2196 47 None None None 77460379 Common - acyl-carrier-protein S-malonyltransferase Pfl_4158 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 77458426 Common - hypothetical protein Pfl_2199 20 None None None 77458641 Nonpathogen - hypothetical protein Pfl_2416 2 None None None 77460421 Common - hypothetical protein Pfl_4200 129 COG0628 PerM, Predicted permease General function prediction only 77457065 Common - Cell shape determining protein MreB/Mrl Pfl_0838 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 77458737 Common - Cytochrome c oxidase cbb3-type, subunit I Pfl_2512 137 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 77459502 Common - hypothetical protein Pfl_3280 24 COG3503 COG3503, Predicted membrane protein Function unknown 77458288 Common - precorrin 6A synthase Pfl_2061 62 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 77456385 Common - Sulfotransferase Pfl_0157 8 None None None 77458419 Common - NADPH-dependent FMN reductase Pfl_2192 106 COG0431 COG0431, Predicted flavoprotein General function prediction only 77459959 Common - TonB-like Pfl_3737 14 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 77459577 Common - Histidine Kinase Pfl_3355 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77460526 Common - hypothetical protein Pfl_4305 83 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 77461733 Common - hypothetical protein Pfl_5512 17 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 77460772 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) and Response Regulator Receiver modulation Pfl_4551 186 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77456633 Common - Type IV pilus assembly protein PilM Pfl_0405 91 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 77459418 Common - hypothetical protein Pfl_3196 19 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 77456460 Common - Acriflavin resistance protein Pfl_0232 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77459683 Common - Tyrosinase Pfl_3461 16 None None None 77461228 Common - 1-deoxy-D-xylulose-5-phosphate synthase Pfl_5007 226 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 77459176 Common - ISPsy6, transposase Pfl_2951 1 None None None 77460488 Nonpathogen - hypothetical protein Pfl_4267 1 None None None 77456321 Common - hypothetical protein Pfl_0093 16 COG4324 COG4324, Predicted aminopeptidase General function prediction only 77458583 Common - Na+/malate symporter Pfl_2356 30 COG3493 CitS, Na+/citrate symporter Energy production and conversion 77458055 Common - hypothetical protein Pfl_1828 37 COG3571 COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 77456580 Common - fructose-1,6-bisphosphatase Pfl_0352 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 77459499 Common - Major facilitator superfamily MFS_1 Pfl_3277 209 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77459395 Common - General secretion pathway protein F Pfl_3173 140 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 77460081 Common - hypothetical protein Pfl_3860 4 None None None 77460582 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase Pfl_4361 124 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 77456954 Common - hypothetical protein Pfl_0726 12 COG4691 StbC, Plasmid stability protein General function prediction only 77457640 Common - Cysteine synthase K/M/A Pfl_1413 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 77459004 Common - Homocysteine S-methyltransferase Pfl_2779 88 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 77460517 Common - BRO-like Pfl_4296 4 COG3617 COG3617, Prophage antirepressor Transcription 77461764 Common - acetylglutamate kinase Pfl_5543 218 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 77461196 Common - 3-methyladenine DNA glycosylase Pfl_4975 46 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 77458619 Common - MscS Mechanosensitive ion channel Pfl_2392 225 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77458452 Common - hypothetical protein Pfl_2225 220 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 77456436 Common - Sulfatase Pfl_0208 84 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 77457831 Common - hypothetical protein Pfl_1604 1 None None None 77459547 Common - hypothetical protein Pfl_3325 1 None None None 77460617 Common - RDD Pfl_4396 50 COG1714 COG1714, Predicted membrane protein/domain Function unknown 77457701 Common - Transcriptional Regulator, AraC family Pfl_1474 136 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77460009 Common - hypothetical protein Pfl_3787 45 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77457838 Common - succinate dehydrogenase, hydrophobic membrane anchor protein Pfl_1611 52 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 77456517 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Pfl_0289 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 77456579 Common - hypothetical protein Pfl_0351 10 None None None 77457129 Common - Alpha/beta hydrolase fold Pfl_0902 85 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77457495 Common - Coenzyme A transferase Pfl_1268 104 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 77459773 Common - hypothetical protein Pfl_3551 2 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 77456725 Common - Metallophosphoesterase Pfl_0497 88 COG1409 Icc, Predicted phosphohydrolases General function prediction only 77458407 Common - Binding-protein-dependent transport systems inner membrane component Pfl_2180 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 77461424 Common - formyltetrahydrofolate deformylase Pfl_5203 220 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 77457467 Common - DoxX Pfl_1240 22 COG2259 COG2259, Predicted membrane protein Function unknown 77461962 Common rnpA ribonuclease P Pfl_5745 55 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 77458199 Common - type II secretion system protein Pfl_1972 141 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 77458133 Common - Ferredoxin Pfl_1906 120 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 77459018 Common - Amino acid permease-associated region Pfl_2793 168 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 77461205 Common - hypothetical protein Pfl_4984 61 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77461284 Common rplR 50S ribosomal protein L18 Pfl_5063 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 77460610 Common - hypothetical protein Pfl_4389 1 None None None 77458754 Common - regulatory protein GntR, HTH Pfl_2529 220 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 77456582 Common - chemotaxis sensory transducer, Cache sensor Pfl_0354 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77456978 Common - Iron-sulfur cluster binding protein Pfl_0751 95 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 77457536 Common - Transcriptional Regulator, XRE family with Cupin sensor domain Pfl_1309 101 COG1476 COG1476, Predicted transcriptional regulators Transcription 77456939 Common - Transcriptional Regulator, LysR family Pfl_0711 95 COG0583 LysR, Transcriptional regulator Transcription 77460275 Common - NAD-dependent epimerase/dehydratase Pfl_4054 130 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77458507 Common - Beta-lactamase-like Pfl_2280 44 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 77459188 Common - Mandelate racemase/muconate lactonizing enzyme Pfl_2963 136 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 77458639 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pfl_2412 14 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 77461872 Common - Cobalamin synthesis protein/P47K Pfl_5652 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 77460345 Common - 2-dehydro-3-deoxy-6-phosphogalactonate aldolase Pfl_4124 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 77456249 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_0021 178 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77460246 Common - CHAD Pfl_4025 1 COG5607 COG5607, Uncharacterized conserved protein Function unknown 77460141 Common - Transcriptional Regulator, MerR family Pfl_3920 109 COG0789 SoxR, Predicted transcriptional regulators Transcription 77460512 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_4291 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 77456996 Common - hypothetical protein Pfl_0769 1 None None None 77456414 Nonpathogen - hypothetical protein Pfl_0186 1 None None None 77459693 Common - Transcriptional Regulator, ArsR family Pfl_3471 35 COG0640 ArsR, Predicted transcriptional regulators Transcription 77460153 Common - diaminobutyrate--2-oxoglutarate aminotransferase Pfl_3932 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 77459340 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3118 219 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 77461236 Common nusB transcription antitermination protein NusB Pfl_5015 190 COG0781 NusB, Transcription termination factor Transcription 77458802 Common - transcriptional regulator, (DeoR-family) Pfl_2577 78 COG2378 COG2378, Predicted transcriptional regulator Transcription 77461336 Common - anthranilate synthase component II Pfl_5115 236 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 77461921 Common - OsmC-like protein Pfl_5701 87 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77457407 Common - hypothetical protein Pfl_1180 1 None None None 77458806 Common - GCN5-related N-acetyltransferase Pfl_2581 41 COG0456 RimI, Acetyltransferases General function prediction only 77458524 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_2297 176 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77460810 Common - hypothetical protein Pfl_4589 2 None None None 77457765 Common fliH flagellar assembly protein H Pfl_1538 62 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 77460666 Nonpathogen - hypothetical protein Pfl_4445 1 None None None 77458527 Common - inner-membrane translocator Pfl_2300 115 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 77456341 Common - NAD/NADP transhydrogenase, membrane-spanning dIIa subunit Pfl_0113 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 77460312 Common - BolA-like protein Pfl_4091 101 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 77461452 Common - Protein of unknown function DUF849 Pfl_5231 62 COG3246 COG3246, Uncharacterized conserved protein Function unknown 77459121 Nonpathogen - hypothetical protein Pfl_2896 1 None None None 77457611 Common - 5-carboxymethyl-2-hydroxymuconate isomerase Pfl_1384 18 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 77459366 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3144 201 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 77458817 Common - Sigma-54 Specific Transcriptional Regulator, Fis family Pfl_2592 173 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77458924 Common - Formate dehydrogenase, beta subunit Pfl_2699 161 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 77456937 Common - regulatory protein, ArsR Pfl_0709 37 COG0640 ArsR, Predicted transcriptional regulators Transcription 77456798 Common - Small multidrug resistance protein Pfl_0570 147 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 161485596 Common fumC fumarate hydratase Pfl_0849 208 COG0114 FumC, Fumarase Energy production and conversion 77461743 Common - cytochrome c5 Pfl_5522 43 COG3245 CycB, Cytochrome c5 Energy production and conversion 77456928 Common - Prenyltransferase/squalene oxidase Pfl_0700 2 COG5029 CAL1, Prenyltransferase, beta subunit Posttranslational modification, protein turnover, chaperones 77459885 Common - Twin-arginine translocation pathway signal Pfl_3663 64 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77458632 Common - hypothetical protein Pfl_2405 1 None None None 77458750 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Pfl_2525 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77461173 Common - hypothetical protein Pfl_4952 198 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 77457180 Common algL poly(beta-D-mannuronate) lyase Pfl_0953 4 None None None 77460803 Common - methyltransferase Pfl_4582 51 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77460502 Common - succinylarginine dihydrolase Pfl_4281 34 COG3724 AstB, Succinylarginine dihydrolase Amino acid transport and metabolism 77457102 Common - Peptidase S1 and S6, chymotrypsin/Hap Pfl_0875 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 77460296 Common - histidinol-phosphate aminotransferase Pfl_4075 234 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 77458965 Common - hypothetical protein Pfl_2740 5 None None None 77458239 Nonpathogen - hypothetical protein Pfl_2012 1 None None None 77459938 Common - hypothetical protein Pfl_3716 1 None None None 77458882 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_2657 127 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77456814 Common - ABC transporter-like Pfl_0586 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 77461240 Common - Riboflavin biosynthesis protein RibD Pfl_5019 229 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 77457660 Common - Carboxylate/Amino Acid/Amine Transporter Pfl_1433 23 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77461624 Common - Spermidine/putrescine ABC transporter ATP-binding subunit Pfl_5403 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77461664 Common - ABC-2 Pfl_5443 144 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 77456741 Common motB flagellar motor protein MotB Pfl_0513 92 COG1360 MotB, Flagellar motor protein Cell motility and secretion 77460722 Common groEL chaperonin GroEL Pfl_4501 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 77461769 Common - hypothetical protein Pfl_5548 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 77458230 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_2003 221 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77460410 Common - Lysine exporter protein (LYSE/YGGA) Pfl_4189 132 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77460412 Common - hypothetical protein Pfl_4191 3 None None None 77457914 Common - Transcriptional Regulator, GntR family Pfl_1687 118 COG2188 PhnF, Transcriptional regulators Transcription 77459240 Common - hypothetical protein Pfl_3018 16 None None None 77461252 Common - dTDP-4-dehydrorhamnose reductase Pfl_5031 147 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 77459219 Common - hypothetical protein Pfl_2997 21 None None None 77461325 Common - 2-nitropropane dioxygenase, NPD Pfl_5104 90 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 77457427 Common - hypothetical protein Pfl_1200 14 None None None 77458446 Common - glycolate oxidase subunit GlcD Pfl_2219 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 77459294 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pfl_3072 148 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 77457848 Common - hypothetical protein Pfl_1621 44 COG3686 COG3686, Predicted membrane protein Function unknown 77456621 Common - Poly(3-hydroxyalkanoate) depolymerase Pfl_0393 129 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77460965 Common - hypothetical protein Pfl_4744 14 None None None 77461169 Common - Sel1-like repeat Pfl_4948 92 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 77457747 Nonpathogen - hypothetical protein Pfl_1520 6 None None None 77456896 Common - Transcriptional Regulator, LysR family Pfl_0668 124 COG0583 LysR, Transcriptional regulator Transcription 77457510 Common - General substrate transporter Pfl_1283 209 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461073 Common ileS isoleucyl-tRNA synthetase Pfl_4852 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77461539 Common - Pilus retraction protein PilT Pfl_5318 202 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 77457637 Common - hypothetical protein Pfl_1410 9 None None None 77458979 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Pfl_2754 162 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 77460886 Common - outer membrane porin Pfl_4665 10 None None None 77457490 Nonpathogen - hypothetical protein Pfl_1263 1 None None None 77461616 Common - Colicin immunity protein/pyocin immunity protein Pfl_5395 8 None None None 77460047 Nonpathogen - hypothetical protein Pfl_3825 1 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 77457165 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_0938 118 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77456949 Common - Gluconate transporter Pfl_0721 80 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 77457964 Common - Transglutaminase-like Pfl_1737 95 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 77456940 Common - Flavin reductase-like, FMN-binding Pfl_0712 120 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 77458859 Common - PfkB Pfl_2634 148 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 77456422 Common - Thiosulphate-binding protein Pfl_0194 89 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 77461811 Nonpathogen - hypothetical protein Pfl_5590 1 None None None 77458911 Common - Lipase, class 3 Pfl_2686 85 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 77458334 Common - Xanthine dehydrogenase Pfl_2107 121 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 77458487 Common - Creatininase Pfl_2260 88 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 77461031 Common - 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK Pfl_4810 195 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 77460949 Common upp uracil phosphoribosyltransferase Pfl_4728 166 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 77456480 Common - Aldo/keto reductase Pfl_0252 194 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 77457669 Common - hypothetical protein Pfl_1442 1 None None None 77457514 Common - hypothetical protein Pfl_1287 61 COG3176 COG3176, Putative hemolysin General function prediction only 77459652 Common - Carboxylyase-like protein Pfl_3430 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 77461395 Common - Alpha/beta hydrolase fold Pfl_5174 51 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77461505 Common - hypothetical protein Pfl_5284 116 COG2353 COG2353, Uncharacterized conserved protein Function unknown 77461890 Common - Band 7 protein Pfl_5670 29 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 77457588 Nonpathogen - hypothetical protein Pfl_1361 1 None None None 77457317 Common - UBA/THIF-type NAD/FAD binding fold Pfl_1090 139 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 77459464 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3242 211 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 77461780 Common - ATP-dependent DNA helicase RecG Pfl_5559 216 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 77459718 Common - hypothetical protein Pfl_3496 3 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 77457387 Common - Phage baseplate assembly protein V Pfl_1160 22 COG4384 COG4384, Mu-like prophage protein gp45 Function unknown 77459999 Common - hypothetical protein Pfl_3777 38 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77459077 Common - argininosuccinate lyase Pfl_2852 216 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 77459961 Common - Biopolymer transport protein ExbD/TolR Pfl_3739 112 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 77460928 Common - Protein of unknown function DUF1329 Pfl_4707 19 None None None 77459269 Nonpathogen - hypothetical protein Pfl_3047 1 None None None 77459816 Common - Isocitrate dehydrogenase (NADP+) Pfl_3594 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 77460383 Common maf Maf-like protein Pfl_4162 190 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 77460684 Common - hypothetical protein Pfl_4463 1 None None None 77458092 Common dkgB 2,5-diketo-D-gluconate reductase B Pfl_1865 189 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 77460894 Common murG N-acetylglucosaminyl transferase Pfl_4673 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 77458585 Common - Transcriptional Regulator, LysR family Pfl_2358 135 COG0583 LysR, Transcriptional regulator Transcription 77461598 Common - PTSINtr with GAF domain, PtsP Pfl_5377 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 77460990 Common - Heat shock protein Hsp70 Pfl_4769 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 77458087 Common - magnesium-transporting ATPase MgtA Pfl_1860 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 77460215 Common - Protein of unknown function DUF81 Pfl_3994 16 COG0730 COG0730, Predicted permeases General function prediction only 77458400 Common - Ferredoxin Pfl_2173 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 77458480 Common - General substrate transporter Pfl_2253 69 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77459766 Common - chorismate mutase Pfl_3544 10 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 77461404 Common - malate synthase G Pfl_5183 68 COG2225 AceB, Malate synthase Energy production and conversion 77459553 Nonpathogen - hypothetical protein Pfl_3331 1 None None None 77460609 Common - carbamate kinase Pfl_4388 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 77461412 Common - hypothetical protein Pfl_5191 1 None None None 77458158 Common thrS threonyl-tRNA synthetase Pfl_1931 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77456986 Common - SmpA/OmlA Pfl_0759 64 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 77460986 Common - Flavin reductase-like, FMN-binding Pfl_4765 76 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 77461725 Common - hypothetical protein Pfl_5504 122 COG0432 COG0432, Uncharacterized conserved protein Function unknown 77458100 Nonpathogen - hypothetical protein Pfl_1873 1 None None None 77458850 Common - hypothetical protein Pfl_2625 15 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 77460093 Common - LexA repressor Pfl_3872 173 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 77458154 Nonpathogen - hypothetical protein Pfl_1927 1 None None None 77459225 Common - hypothetical protein Pfl_3003 21 None None None 77459538 Common - hypothetical protein Pfl_3316 7 None None None 77457957 Common - hypothetical protein Pfl_1730 1 None None None 77460076 Common - Two component Heavy metal response Transcriptional regulator, Winged helix family Pfl_3855 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77459622 Common - 2-hydroxyacid dehydrogenase Pfl_3400 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 77457735 Common - Glycosyl transferase, family 2 Pfl_1508 105 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 77457689 Common - Type I secretion outer membrane protein, TolC Pfl_1462 131 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77461062 Common - FAD dependent oxidoreductase Pfl_4841 150 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77459030 Common - Aldehyde dehydrogenase Pfl_2805 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77456667 Common - acyl carrier protein, putative Pfl_0439 48 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77456572 Common - Glutamine synthetase type I Pfl_0344 227 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 77461827 Common - Two component Transcriptional regulator, Winged helix family Pfl_5606 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77457451 Common - hypothetical protein Pfl_1224 19 COG5615 COG5615, Predicted integral membrane protein Function unknown 77458193 Common - hypothetical protein Pfl_1966 101 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 77456560 Common - Peptidase M23B Pfl_0332 185 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 77461790 Nonpathogen - hypothetical protein Pfl_5569 1 None None None 77456267 Common - hypothetical protein Pfl_0039 90 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 77459563 Common - GCN5-related N-acetyltransferase Pfl_3341 93 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 77456376 Common - GCN5-related N-acetyltransferase Pfl_0148 9 COG0456 RimI, Acetyltransferases General function prediction only 77459820 Common - adenylosuccinate lyase Pfl_3598 234 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 77460788 Common - hypothetical protein Pfl_4567 3 None None None 77456264 Common - hypothetical protein Pfl_0036 12 None None None 77460720 Common - Sulfatase Pfl_4499 72 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 77459324 Common - Cobalamin (vitamin B12) biosynthesis CbiG protein Pfl_3102 9 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 77460432 Common - Periplasmic Sensor Hybrid Histidine Kinase Pfl_4211 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77460136 Common - FMN reductase Pfl_3915 50 COG0431 COG0431, Predicted flavoprotein General function prediction only 77461271 Common - General substrate transporter Pfl_5050 231 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77460231 Common - hypothetical protein Pfl_4010 32 COG2388 COG2388, Predicted acetyltransferase General function prediction only 77456819 Common - transport system permease protein Pfl_0591 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 77456420 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Pfl_0192 188 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77457759 Common - Sigma-54 Specific Transcriptional Regulator, Fis family Pfl_1532 171 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77458181 Common - Transcriptional Regulator, LysR family Pfl_1954 163 COG0583 LysR, Transcriptional regulator Transcription 77459110 Common - Sigma-24 (FecI) Pfl_2885 129 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77457505 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_1278 141 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77460711 Common - lipoprotein, putative Pfl_4490 24 COG3489 COG3489, Predicted periplasmic lipoprotein General function prediction only 77457821 Common - pyruvate kinase Pfl_1594 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 77459194 Common - Transcriptional Regulator, AraC family Pfl_2969 98 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77459397 Common - type II and III secretion system protein Pfl_3175 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 77457211 Common - Histone-like DNA-binding protein Pfl_0984 188 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 77456733 Common - Histidine kinase, HAMP region Pfl_0505 1 COG3726 AhpA, Uncharacterized membrane protein affecting hemolysin expression General function prediction only 77458303 Common - 3-oxoacid CoA-transferase Pfl_2076 102 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 77456495 Common hslO Hsp33-like chaperonin Pfl_0267 133 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 77458457 Common - ThiJ/PfpI Pfl_2230 107 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 77457457 Common - hypothetical protein Pfl_1230 1 None None None 77458399 Common - Alpha/beta hydrolase fold Pfl_2172 144 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77461753 Common - Phospholipase D/Transphosphatidylase Pfl_5532 105 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 77456343 Nonpathogen - hypothetical protein Pfl_0115 1 None None None 77461802 Common - FHA domain containing protein Pfl_5581 30 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 77456305 Common - cytochrome C oxidase assembly protein Pfl_0077 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 77457436 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_1209 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 77457590 Common - Anti Sigma-E protein, RseA Pfl_1363 4 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 77458825 Common - Nicotinamide mononucleotide transporter PnuC Pfl_2600 54 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 77461886 Common - Cyclopropane-fatty-acyl-phospholipid synthase Pfl_5666 157 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 77460702 Common - hypothetical protein Pfl_4481 1 COG5185 HEC1, Protein involved in chromosome segregation, interacts with SMC proteins Cell division and chromosome partitioning 77459531 Common - Protein of unknown function DUF6, transmembrane Pfl_3309 97 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77456710 Nonpathogen - hypothetical protein Pfl_0482 6 None None None 77459952 Common - hypothetical protein Pfl_3730 12 None None None 77457871 Common cobD cobalamin biosynthesis protein Pfl_1644 151 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 77458000 Common - Mg2+ transporter protein, CorA-like Pfl_1773 76 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 77457948 Common - Alpha/beta hydrolase fold Pfl_1721 34 COG2267 PldB, Lysophospholipase Lipid metabolism 77458124 Common - N-(5'-phosphoribosyl)anthranilate isomerase Pfl_1897 197 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 77461854 Common - Negative transcriptional regulator Pfl_5634 60 COG2808 PaiB, Transcriptional regulator Transcription 77458390 Common - ThiJ/PfpI Pfl_2163 64 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 77461037 Common - Protein of unknown function DUF748 Pfl_4816 44 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 77459519 Nonpathogen - hypothetical protein Pfl_3297 1 None None None 77460535 Common - Glycerophosphodiester phosphodiesterase Pfl_4314 140 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 77460675 Common - Insecticidal toxin protein, putative Pfl_4454 56 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 77456362 Common - Type I secretion outer membrane protein, TolC Pfl_0134 132 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77456482 Common - Binding-protein-dependent transport systems inner membrane component Pfl_0254 199 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 77460201 Common - Transcriptional Regulator, MarR family Pfl_3980 75 COG1846 MarR, Transcriptional regulators Transcription 77460851 Nonpathogen - hypothetical protein Pfl_4630 1 None None None 77459006 Common - Glycine betaine/L-proline ABC transporter, ATPase/permease fusion protein, putative Pfl_2781 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 77459411 Common - PAAR Pfl_3189 11 COG4104 COG4104, Uncharacterized conserved protein Function unknown 77458793 Common - Protein of unknown function DUF883 Pfl_2568 1 COG4575 ElaB, Uncharacterized conserved protein Function unknown 77458745 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Pfl_2520 106 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77457705 Common - Transcriptional Regulator, AraC family Pfl_1478 82 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77457340 Common - UDP-N-acetylglucosamine acyltransferase Pfl_1113 166 COG1043 LpxA, Acyl- acyl carrier protein 77459904 Common - Transcriptional Regulator, LysR family Pfl_3682 191 COG0583 LysR, Transcriptional regulator Transcription 77457800 Common - hypothetical protein Pfl_1573 11 None None None 77460220 Common - elongation factor P Pfl_3999 215 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 77461713 Common - hypothetical protein Pfl_5492 7 None None None 77460750 Common - Phenazine biosynthesis PhzC/PhzF protein Pfl_4529 121 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 77457247 Common rimM 16S rRNA-processing protein Pfl_1020 184 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 77457465 Common - short chain dehydrogenase Pfl_1238 53 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77460621 Common - hypothetical protein Pfl_4400 92 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 77458994 Common - Short-chain dehydrogenase/reductase SDR Pfl_2769 236 COG3967 DltE, Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 77459422 Common - hypothetical protein Pfl_3200 4 None None None 77459429 Common - hypothetical protein Pfl_3207 1 None None None 77458567 Common - ABC transporter binding protein Pfl_2340 55 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 77459764 Common - Protein of unknown function DUF925 Pfl_3542 26 COG3575 COG3575, Uncharacterized protein conserved in bacteria Function unknown 77458035 Common recR recombination protein RecR Pfl_1808 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 77458591 Common - Aldehyde dehydrogenase Pfl_2364 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77456973 Common - Phage integrase Pfl_0746 16 None None None 77458205 Common - hypothetical protein Pfl_1978 49 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 77460325 Common - Carbon storage regulator, CsrA Pfl_4104 76 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 77456526 Common - AzlC-like Pfl_0298 98 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 77458038 Common - Transcriptional Regulator, Crp/Fnr family Pfl_1811 150 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 77456315 Common - Protein tyrosine/serine phosphatase Pfl_0087 13 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 77459808 Common - Cell division FtsK/SpoIIIE Pfl_3586 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 77458683 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_2458 219 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77456830 Common cbiD cobalt-precorrin-6A synthase Pfl_0602 83 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 77460208 Common - DEAD/DEAH box helicase-like Pfl_3987 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77461836 Common - Phosphate binding protein Pfl_5615 116 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 77460661 Common - integral membrane protein Pfl_4440 40 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 77461392 Common - hypothetical protein Pfl_5171 1 None None None 77460240 Common - DoxX Pfl_4019 55 COG2259 COG2259, Predicted membrane protein Function unknown 77458071 Common - Thioesterase Pfl_1844 50 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 77456614 Common - Protein of unknown function DUF1243 Pfl_0386 47 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 77460394 Common - 3-deoxy-manno-octulosonate cytidylyltransferase Pfl_4173 138 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 77460588 Common - ABC transporter-like Pfl_4367 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 77459500 Common - Short-chain dehydrogenase/reductase SDR Pfl_3278 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77460167 Common - Short-chain dehydrogenase/reductase SDR Pfl_3946 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77460743 Common - BFD-like (2Fe-2S)-binding region Pfl_4522 38 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 77461156 Common - ATP-dependent helicase HrpB Pfl_4935 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 77460229 Common - hypothetical protein Pfl_4008 5 None None None 77457493 Common - Benzoate transport Pfl_1266 134 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77457023 Common - Alkaline phosphatase Pfl_0796 60 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 77459510 Common - hypothetical protein Pfl_3288 1 None None None 77459249 Common - hypothetical protein Pfl_3027 22 None None None 77456825 Common - hypothetical protein Pfl_0597 2 COG3667 PcoB, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 77460952 Common - hypothetical protein Pfl_4731 105 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 77457287 Common lysS lysyl-tRNA synthetase Pfl_1060 247 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 77458658 Common - ABC transporter-like Pfl_2433 248 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 77461897 Common - Acyltransferase 3 Pfl_5677 75 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 77460171 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Pfl_3950 240 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 77459509 Common - Transcriptional antiterminator, Rof Pfl_3287 14 COG4568 Rof, Transcriptional antiterminator Transcription 77460775 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_4554 130 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77458722 Common - surface antigen (D15) Pfl_2497 58 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 77459635 Nonpathogen - hypothetical protein Pfl_3413 1 None None None 77460289 Common - hypothetical protein Pfl_4068 11 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 77457919 Common - Pseudouridine synthase Pfl_1692 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 77457061 Common - Rare lipoprotein A Pfl_0834 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 77460731 Common - Electron transport complex, RnfABCDGE type, D subunit Pfl_4510 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 77456427 Common - Transcriptional Regulator, Crp/Fnr family Pfl_0199 105 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 77457717 Common - Predicted transcriptional regulator Pfl_1490 141 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 77461547 Common - putative deoxyribonucleotide triphosphate pyrophosphatase Pfl_5326 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 77456446 Common - TonB-like Pfl_0218 37 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 77460932 Common - glycerate dehydrogenase Pfl_4711 229 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 77458686 Common - Alpha/beta hydrolase fold Pfl_2461 152 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77458559 Common - PAAR Pfl_2332 19 COG4104 COG4104, Uncharacterized conserved protein Function unknown 77459305 Common - PAS/PAC Sensor Hybrid Histidine Kinase Pfl_3083 218 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77456282 Common - cytochrome c-type protein Pfl_0054 45 COG3245 CycB, Cytochrome c5 Energy production and conversion 77457534 Common - Dihydrodipicolinate synthetase Pfl_1307 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 77461529 Common - Response regulator receiver domain protein (CheY) Pfl_5308 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77456969 Nonpathogen - hypothetical protein Pfl_0742 1 None None None 77460553 Common - transcription activator, effector binding Pfl_4332 19 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 77456840 Common - phosphoribosylamine--glycine ligase Pfl_0612 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 77460061 Nonpathogen - hypothetical protein Pfl_3840 1 None None None 77460874 Common - anaerobic nitric oxide reductase transcription regulator Pfl_4653 170 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 77461378 Common pqqA coenzyme PQQ synthesis protein PqqA Pfl_5157 1 None None None 77458946 Common - Short-chain dehydrogenase/reductase SDR Pfl_2721 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77457219 Common - GTP-binding protein LepA Pfl_0992 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 77458765 Common - Glycosyl transferase, family 2 Pfl_2540 28 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77460736 Common - Two Component Transcriptional Regulator, LuxR family Pfl_4515 223 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77458958 Common - Protein of unknown function DUF985 Pfl_2733 55 COG3542 COG3542, Uncharacterized conserved protein Function unknown 77460285 Common - ABC-2 Pfl_4064 80 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 77458955 Common - Cytidine/deoxycytidylate deaminase, zinc-binding region Pfl_2730 183 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 77457936 Nonpathogen - hypothetical protein Pfl_1709 1 None None None 77457397 Common - Carbohydrate-binding, CenC-like Pfl_1170 6 None None None 77460581 Common - Intradiol ring-cleavage dioxygenase Pfl_4360 32 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 77460280 Common - hypothetical protein Pfl_4059 1 None None None 77460888 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Pfl_4667 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 77458977 Common - Possible Transcriptional Regulator, TetR family Pfl_2752 5 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 77459372 Common - hypothetical protein Pfl_3150 66 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 77460668 Common - hypothetical protein Pfl_4447 1 None None None 77458254 Common - Protein of unknown function DUF214 Pfl_2027 43 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 77460850 Nonpathogen - hypothetical protein Pfl_4629 1 None None None 77456569 Common - hypothetical protein Pfl_0341 17 None None None 77460250 Common - Two component Transcriptional regulator, Winged helix family Pfl_4029 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77459492 Common - Permease for cytosine/purines, uracil, thiamine, allantoin Pfl_3270 47 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 77460699 Common - 4-hydroxybenzoate 3-monooxygenase Pfl_4478 86 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 77457470 Common - hypothetical protein Pfl_1243 6 COG5572 COG5572, Predicted integral membrane protein Function unknown 77459311 Common - ABC transporter-like Pfl_3089 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 77457781 Common - hypothetical protein Pfl_1554 9 None None None 77461385 Common - Aminotransferase class-III Pfl_5164 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 77456818 Common - branched-chain amino acid ABC transporter, periplasmic amino acid-binding protein Pfl_0590 112 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 77457305 Common - Transcriptional Regulator, TetR family Pfl_1078 109 COG1309 AcrR, Transcriptional regulator Transcription 77457352 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_1125 208 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 77457763 Common fliF flagellar MS-ring protein Pfl_1536 127 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 77457788 Common flhF flagellar biosynthesis regulator FlhF Pfl_1561 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 77458541 Common - YjgF-like protein Pfl_2314 178 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77458249 Common - ATPase involved in chromosome partitioning-like Pfl_2022 37 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77457100 Common - hypothetical protein Pfl_0873 10 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 77460030 Nonpathogen - hypothetical protein Pfl_3808 1 None None None 77457449 Common - hypothetical protein Pfl_1222 1 COG3776 COG3776, Predicted membrane protein Function unknown 77458362 Common - hypothetical protein Pfl_2135 2 None None None 77458889 Common - GTP-binding protein, HSR1-like Pfl_2664 4 COG1160 COG1160, Predicted GTPases General function prediction only 77457136 Common - Transcriptional Regulator, IclR family Pfl_0909 112 COG1414 IclR, Transcriptional regulator Transcription 77456396 Common - YbaK/prolyl-tRNA synthetase associated region Pfl_0168 33 COG2606 EbsC, Uncharacterized conserved protein Function unknown 77461774 Common - lipoprotein, putative Pfl_5553 1 None None None 77458512 Common solA N-methyltryptophan oxidase Pfl_2285 76 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77459751 Common - Response regulator receiver domain protein (CheY) Pfl_3529 121 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77456921 Common - OmpA/MotB Pfl_0693 160 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77459657 Common - Phosphodiesterase/alkaline phosphatase D-like Pfl_3435 31 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 77459853 Common - hypothetical protein Pfl_3631 25 COG5477 COG5477, Predicted small integral membrane protein Function unknown 77460832 Common - scaffold protein Pfl_4611 151 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 77458546 Nonpathogen - hypothetical protein Pfl_2319 1 None None None 77457035 Nonpathogen - hypothetical protein Pfl_0808 1 None None None 77461960 Common - putative inner membrane protein translocase component YidC Pfl_5743 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 77457085 Common - ABC transporter-like Pfl_0858 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 77456607 Common - hypothetical protein Pfl_0379 71 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 77461362 Common - hypothetical protein Pfl_5141 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 77460759 Common - ABC transporter-like Pfl_4538 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 77461403 Common - Amino acid-binding ACT Pfl_5182 31 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 77457009 Common rpsO 30S ribosomal protein S15 Pfl_0782 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 77459203 Common - hypothetical protein Pfl_2978 1 None None None 77458598 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pfl_2371 206 COG0388 COG0388, Predicted amidohydrolase General function prediction only 77459931 Common - Sodium:dicarboxylate symporter Pfl_3709 155 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 77461557 Common - ABC transporter-like Pfl_5336 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 77461167 Common thiE thiamine-phosphate pyrophosphorylase Pfl_4946 186 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 77459704 Nonpathogen - hypothetical protein Pfl_3482 1 None None None 77459839 Nonpathogen - hypothetical protein Pfl_3617 1 None None None 77461514 Common - Transcriptional Regulator, LysR family Pfl_5293 174 COG0583 LysR, Transcriptional regulator Transcription 77458577 Common - hypothetical protein Pfl_2350 1 None None None 77460637 Common - hypothetical protein Pfl_4416 34 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 77459258 Common - hypothetical protein Pfl_3036 26 COG5478 COG5478, Predicted small integral membrane protein Function unknown 77460108 Common - Multi antimicrobial extrusion protein MatE Pfl_3887 182 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 77458265 Nonpathogen - hypothetical protein Pfl_2038 1 None None None 77458026 Common - Chromosome segregation protein SMC Pfl_1799 188 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 77457985 Common - Phosphoserine phosphatase/homoserine phosphotransferase bifunctional protein Pfl_1758 24 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 77456991 Common - Heat shock protein DnaJ Pfl_0764 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 77456333 Common - hypothetical protein Pfl_0105 11 None None None 77457576 Common - uracil-DNA glycosylase Pfl_1349 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 77458530 Common - xylose isomerase Pfl_2303 68 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 77459343 Common - TonB-dependent receptor Pfl_3121 104 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77456474 Common - transferase hexapeptide repeat Pfl_0246 191 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 77459146 Common - transcriptional regulator, putative Pfl_2921 4 None None None 77457261 Common - YaeQ Pfl_1034 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 77458136 Common - FAD dependent oxidoreductase Pfl_1909 120 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77457127 Common - LrgB-like protein Pfl_0900 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 77461019 Common - ABC transporter-like Pfl_4798 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 77461541 Common - pyrroline-5-carboxylate reductase Pfl_5320 216 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 77458901 Common - Protein of unknown function DUF861 Pfl_2676 27 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 77461468 Common - Drug resistance transporter EmrB/QacA subfamily Pfl_5247 186 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77458438 Common - Amino acid adenylation Pfl_2211 220 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77458168 Nonpathogen - hypothetical protein Pfl_1941 2 None None None 77457626 Common - Oligopeptidase B Pfl_1399 100 COG1770 PtrB, Protease II Amino acid transport and metabolism 77461015 Common - Pentapeptide repeat Pfl_4794 12 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 77457182 Common - Carbohydrate binding and sugar hydrolysis Pfl_0955 10 None None None 77461286 Common rpsH 30S ribosomal protein S8 Pfl_5065 233 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 77458018 Common - hypothetical protein Pfl_1791 28 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 77457485 Common - Endoribonuclease L-PSP Pfl_1258 89 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77456762 Common rpsF 30S ribosomal protein S6 Pfl_0534 195 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 77457842 Common - dihydrolipoamide acetyltransferase Pfl_1615 194 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 77459613 Common - Two component Transcriptional regulator, Winged helix family Pfl_3391 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77458918 Common - Sodium/hydrogen exchanger Pfl_2693 69 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 77456913 Common - beta alanine--pyruvate transaminase Pfl_0685 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 77461247 Common - ABC transporter-like Pfl_5026 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 77457190 Common - PhoH-like protein Pfl_0963 199 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 77461094 Common - GreA/GreB family elongation factor Pfl_4873 142 COG0782 GreA, Transcription elongation factor Transcription 77457671 Common - hypothetical protein Pfl_1444 14 None None None 77458040 Common - coproporphyrinogen III oxidase Pfl_1813 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 77459333 Common - hypothetical protein Pfl_3111 1 None None None 77456237 Common glyS glycyl-tRNA synthetase subunit beta Pfl_0009 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 77460564 Common - chemotaxis sensory transducer, Pas/Pac sensor Pfl_4343 109 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77458536 Common - Amino acid permease-associated region Pfl_2309 188 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 77460497 Common - Threonine aldolase Pfl_4276 103 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 77460866 Common - Cytochrome C oxidase subunit IV Pfl_4645 57 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 77456864 Common - hypothetical protein Pfl_0636 11 COG4655 COG4655, Predicted membrane protein Function unknown 77460157 Common - Protein-disulfide reductase Pfl_3936 92 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 77459228 Common - hypothetical protein Pfl_3006 10 None None None 77460219 Common - Esterase/lipase/thioesterase Pfl_3998 135 COG0657 Aes, Esterase/lipase Lipid metabolism 77458789 Common - Putative FecR Pfl_2564 46 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77458908 Common - Outer membrane autotransporter barrel Pfl_2683 152 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 77460465 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_4244 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77458535 Common - Proline racemase Pfl_2308 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 77458692 Common - hypothetical protein Pfl_2467 1 None None None 77458609 Common - Endoribonuclease L-PSP Pfl_2382 88 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77458600 Common - Twin-arginine translocation pathway signal Pfl_2373 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 77457195 Common - hypothetical protein Pfl_0968 45 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 77457336 Common - surface antigen (D15) Pfl_1109 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 77461483 Common - fructose-1,6-bisphosphate aldolase Pfl_5262 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 77461343 Common - Binding-protein-dependent transport systems inner membrane component Pfl_5122 203 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 77459997 Common - hypothetical protein Pfl_3775 14 None None None 77456795 Common - Ferritin and Dps Pfl_0567 119 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 77459438 Common - Exonuclease SbcD Pfl_3216 100 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 77461160 Common - Transcriptional Regulator, AsnC family Pfl_4939 146 COG1522 Lrp, Transcriptional regulators Transcription 77459022 Common - Amidohydrolase 2 Pfl_2797 33 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 77461932 Common - Transcriptional Regulator, Winged helix family Pfl_5714 48 COG3903 COG3903, Predicted ATPase General function prediction only 77456555 Common - imidazole glycerol phosphate synthase subunit HisF Pfl_0327 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 77457072 Common - Peptidase U62, modulator of DNA gyrase Pfl_0845 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 77459301 Common - 3-hydroxybutyrate dehydrogenase Pfl_3079 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77460705 Common - hypothetical protein Pfl_4484 21 COG3602 COG3602, Uncharacterized protein conserved in bacteria Function unknown 77456638 Common aroK shikimate kinase Pfl_0410 200 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 77461577 Common - hypothetical protein Pfl_5356 7 None None None 77456484 Common - Taurine ABC transporter, periplasmic binding protein Pfl_0256 93 COG4521 TauA, ABC-type taurine transport system, periplasmic component Inorganic ion transport and metabolism 77458242 Common - Polysaccharide deacetylase Pfl_2015 49 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 77457140 Common - General substrate transporter Pfl_0913 145 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77461606 Common - Fumarylacetoacetate (FAA) hydrolase Pfl_5385 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 77461299 Common rplD 50S ribosomal protein L4 Pfl_5078 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 77457158 Common - TonB-dependent siderophore receptor Pfl_0931 121 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77461948 Common - F0F1 ATP synthase subunit gamma Pfl_5731 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 77456658 Common - hypothetical protein Pfl_0430 30 COG4258 COG4258, Predicted exporter General function prediction only 77457363 Common - hypothetical protein Pfl_1136 1 None None None 77457901 Common - hypothetical protein Pfl_1674 2 None None None 77456230 Common - DNA polymerase III subunit beta Pfl_0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 77460038 Common - Transposase IS116/IS110/IS902 Pfl_3816 100 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 77456593 Common - Histidine ammonia-lyase Pfl_0365 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 77461189 Common - Lytic murein transglycosylase B Pfl_4968 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 77457752 Common - hypothetical protein Pfl_1525 18 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 77460116 Common - Histone deacetylase superfamily Pfl_3895 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 77456532 Common - hypothetical protein Pfl_0304 6 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 77459386 Common - Transcriptional Regulator, GntR family Pfl_3164 128 COG2188 PhnF, Transcriptional regulators Transcription 77460045 Common - hypothetical protein Pfl_3823 3 None None None 77460797 Common - Carbohydrate-selective porin OprB Pfl_4576 22 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 77461581 Common - Sodium:dicarboxylate symporter Pfl_5360 158 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 77460299 Common - DNA gyrase subunit A Pfl_4078 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 77458853 Common - hypothetical protein Pfl_2628 18 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 77458188 Common - Beta-lactamase-like Pfl_1961 73 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77457237 Common - NUDIX hydrolase Pfl_1010 131 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 77457951 Common - hypothetical protein Pfl_1724 112 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 77459431 Common - Protein of unknown function DUF58 Pfl_3209 87 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 77458380 Common - Transcriptional Regulator, LysR family Pfl_2153 122 COG0583 LysR, Transcriptional regulator Transcription 77460994 Common - Carbonic anhydrase Pfl_4773 148 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 77460409 Common - hypothetical protein Pfl_4188 7 None None None 77459039 Common - Polysaccharide export protein Pfl_2814 108 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 77458343 Common - 2',5' RNA ligase Pfl_2116 59 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 77459668 Common - Copper resistance protein CopC Pfl_3446 44 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 77461524 Common - CheW protein Pfl_5303 9 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77461474 Common - hypothetical protein Pfl_5253 9 COG4519 COG4519, Uncharacterized protein conserved in bacteria Function unknown 77457079 Common - Zinc transporter ZIP Pfl_0852 71 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 77458065 Nonpathogen - hypothetical protein Pfl_1838 1 None None None 77457907 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_1680 171 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77458646 Nonpathogen - probable dehydrogenase Pfl_2421 2 None None None 77456758 Common - Binding-protein-dependent transport systems inner membrane component Pfl_0530 161 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 77461699 Common - ABC transporter-like Pfl_5478 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 77457105 Common - bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein Pfl_0878 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 77460576 Common - Alpha/beta hydrolase fold Pfl_4355 107 COG2267 PldB, Lysophospholipase Lipid metabolism 77459064 Common - ABC transporter-like Pfl_2839 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77460074 Common queF 7-cyano-7-deazaguanine reductase Pfl_3853 106 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 77459382 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3160 181 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 77460428 Common - hypothetical protein Pfl_4207 12 None None None 77460633 Common - hypothetical protein Pfl_4412 72 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 77458981 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_2756 108 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77460845 Nonpathogen - hypothetical protein Pfl_4624 2 None None None 77456908 Common - inner-membrane translocator Pfl_0680 103 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 77458870 Common - Response regulator receiver domain protein (CheY) Pfl_2645 184 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77460053 Common - hypothetical protein Pfl_3831 21 None None None 77458371 Common - Chromate transporter Pfl_2144 113 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 77458495 Common - hypothetical protein Pfl_2268 1 None None None 77459954 Common - Aldo/keto reductase Pfl_3732 190 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 77459797 Common - hypothetical protein Pfl_3575 41 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 77457120 Common - hypothetical protein Pfl_0893 28 COG3224 COG3224, Uncharacterized protein conserved in bacteria Function unknown 77457291 Common - lipoprotein, putative Pfl_1064 81 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 77456756 Common - adenylosuccinate synthetase Pfl_0528 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 77458117 Common leuD isopropylmalate isomerase small subunit Pfl_1890 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 77457145 Common - hypothetical protein Pfl_0918 1 None None None 77456854 Common - translation initiation factor Sui1 Pfl_0626 86 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 77458716 Common - hypothetical protein Pfl_2491 18 COG1289 COG1289, Predicted membrane protein Function unknown 77457599 Common - lipoprotein, putative Pfl_1372 31 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 77460693 Common - Transcriptional Regulator, LysR family Pfl_4472 153 COG0583 LysR, Transcriptional regulator Transcription 77456641 Common gltB glutamate synthase subunit alpha Pfl_0413 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 77458877 Common - Histidine Kinase Pfl_2652 218 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77458140 Nonpathogen - hypothetical protein Pfl_1913 1 None None None 77457854 Common - Pirin-like Pfl_1627 143 COG1741 COG1741, Pirin-related protein General function prediction only 77461640 Common - N-acetylglutamate synthase Pfl_5419 196 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 77458668 Common - Transcriptional Regulator, LysR family Pfl_2443 186 COG0583 LysR, Transcriptional regulator Transcription 77459869 Common - surface antigen (D15) Pfl_3647 140 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 77459747 Common - Protein of unknown function DUF559 Pfl_3525 46 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 77459753 Common - Response regulator receiver domain protein (CheY) Pfl_3531 44 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 77461065 Common - type IV pilus assembly protein PilX Pfl_4844 1 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 77457826 Common - Protein of unknown function DUF336 Pfl_1599 67 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 77461146 Common - Protein of unknown function DUF88 Pfl_4925 57 COG1432 COG1432, Uncharacterized conserved protein Function unknown 77461479 Common - Transcriptional Regulator, XRE family Pfl_5258 5 COG1476 COG1476, Predicted transcriptional regulators Transcription 77456874 Common - type II secretion system protein E Pfl_0646 158 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 77458797 Common - lipoprotein, putative Pfl_2572 17 COG5608 COG5608, Conserved secreted protein Function unknown 77459882 Common - Putative prophage repressor Pfl_3660 22 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 77456454 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_0226 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77457377 Common - Phage tail X Pfl_1150 10 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 77461353 Common - Organic solvent tolerance protein Pfl_5132 127 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 77456406 Common - Polysaccharide deacetylase Pfl_0178 70 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 77461694 Common - hypothetical protein Pfl_5473 7 COG5633 COG5633, Predicted periplasmic lipoprotein General function prediction only 77460063 Common - hypothetical protein Pfl_3842 3 COG2327 WcaK, Uncharacterized conserved protein Function unknown 77459234 Common - hypothetical protein Pfl_3012 33 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 77461180 Common holA DNA polymerase III subunit delta Pfl_4959 118 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 77461048 Common - hypothetical protein Pfl_4827 5 None None None 77457678 Nonpathogen - hypothetical protein Pfl_1451 1 None None None 77461275 Common rplQ 50S ribosomal protein L17 Pfl_5054 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 77459379 Common - hypothetical protein Pfl_3157 12 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 77457550 Common - Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain Pfl_1323 186 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77459525 Common - Two component Transcriptional regulator, Winged helix family Pfl_3303 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77458571 Common - lipoprotein, putative Pfl_2344 17 None None None 77461762 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase Pfl_5541 177 COG0756 Dut, dUTPase Nucleotide transport and metabolism 77459208 Common - ISPsy12, transposase OrfB Pfl_2983 11 None None None 77458301 Common - acetyl-CoA acetyltransferase Pfl_2074 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77459497 Common - Transcriptional Regulator, LysR family Pfl_3275 187 COG0583 LysR, Transcriptional regulator Transcription 77460127 Common - Transcriptional Regulator, TetR family Pfl_3906 41 COG1309 AcrR, Transcriptional regulator Transcription 77459353 Common - hypothetical protein Pfl_3131 1 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 77461537 Common - TM2 Pfl_5316 23 COG2314 XynA, Predicted membrane protein Function unknown 77460473 Common - MCP methyltransferase, CheR-type Pfl_4252 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 77457368 Common - Baseplate J-like protein Pfl_1141 27 COG3948 COG3948, Phage-related baseplate assembly protein General function prediction only 77461319 Common - tyrosyl-tRNA synthetase Pfl_5098 241 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77459862 Common - Peptidyl-prolyl cis-trans isomerase, cyclophilin type Pfl_3640 199 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 77459976 Common - tRNA 2-selenouridine synthase Pfl_3754 65 COG2603 COG2603, Predicted ATPase General function prediction only 77459957 Common - Predicted signal-transduction protein containing CBS domains Pfl_3735 184 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 77459949 Common - hypothetical protein Pfl_3727 2 None None None 77461841 Common - Transglycosylase-associated protein Pfl_5620 53 COG2261 COG2261, Predicted membrane protein Function unknown 77461231 Common - hypothetical protein Pfl_5010 1 None None None 77457259 Common - hypothetical protein Pfl_1032 7 None None None 77460792 Common - hypothetical protein Pfl_4571 2 None None None 77456717 Common - Transcriptional Regulator, LysR family Pfl_0489 149 COG0583 LysR, Transcriptional regulator Transcription 77456780 Common - Extracellular ligand-binding receptor Pfl_0552 118 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 77457392 Common - putative tail fiber assembly-like protein Pfl_1165 2 None None None 77458416 Common - GCN5-related N-acetyltransferase Pfl_2189 10 COG0456 RimI, Acetyltransferases General function prediction only 77458317 Common - GCN5-related N-acetyltransferase Pfl_2090 14 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 77458367 Common - hypothetical protein Pfl_2140 5 None None None 77459361 Common - Excinuclease ABC, A subunit Pfl_3139 242 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 77460189 Common - Rh-like protein/ammonium transporter Pfl_3968 202 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 77459640 Common - Aminoglycoside phosphotransferase Pfl_3418 60 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 77461187 Common - Serine-type D-Ala-D-Ala carboxypeptidase Pfl_4966 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 77458929 Common - hypothetical protein Pfl_2704 1 None None None 77460279 Common - dTDP-glucose 4,6-dehydratase Pfl_4058 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 77456787 Common - N-acylglucosamine 2-epimerase Pfl_0559 30 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 77458747 Common - Acriflavin resistance protein Pfl_2522 184 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77456383 Common - Phage Tail Collar Pfl_0155 34 COG4675 MdpB, Microcystin-dependent protein Function unknown 77457742 Common - transferase hexapeptide repeat Pfl_1515 225 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 77458920 Common - Short-chain dehydrogenase/reductase SDR Pfl_2695 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77458810 Common - hypothetical protein Pfl_2585 1 None None None 77459504 Common - Transcriptional Regulator, LysR family Pfl_3282 176 COG0583 LysR, Transcriptional regulator Transcription 77458529 Common - Periplasmic binding protein/LacI transcriptional regulator Pfl_2302 95 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 77461041 Common - type II secretion system protein E Pfl_4820 214 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 77459015 Nonpathogen - hypothetical protein Pfl_2790 1 None None None 77460944 Common - hypothetical protein Pfl_4723 1 None None None 77458428 Common - haem catalase/peroxidase Pfl_2201 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 77458831 Common acpD azoreductase Pfl_2606 99 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 77456696 Common - Lipopolysaccharide kinase Pfl_0468 10 None None None 77459442 Nonpathogen - hypothetical protein Pfl_3220 1 None None None 77459451 Common - hypothetical protein Pfl_3229 63 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 77460310 Common - hypothetical protein Pfl_4089 37 COG3531 COG3531, Predicted protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 77456300 Common - Cytochrome oxidase assembly Pfl_0072 46 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 77460374 Common - Aminodeoxychorismate lyase Pfl_4153 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 77458735 Nonpathogen - hypothetical protein Pfl_2510 1 None None None 77457500 Common - 3-carboxy-cis,cis-muconate cycloisomerase Pfl_1273 237 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 77458768 Common - hypothetical protein Pfl_2543 23 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77456388 Common - Glycosyl hydrolase, BNR repeat Pfl_0160 147 None None None 77459174 Nonpathogen - hypothetical protein Pfl_2949 1 None None None 77458643 Common - hypothetical protein Pfl_2418 12 COG1432 COG1432, Uncharacterized conserved protein Function unknown 77456392 Common - hypothetical protein Pfl_0164 9 COG2985 COG2985, Predicted permease General function prediction only 77458773 Common - Alpha amylase, catalytic region Pfl_2548 161 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 77460265 Common - MaoC-like dehydratase Pfl_4044 84 COG2030 MaoC, Acyl dehydratase Lipid metabolism 77458581 Common - hypothetical protein Pfl_2354 4 None None None 77458637 Common - hypothetical protein Pfl_2410 1 None None None 77457532 Nonpathogen - hypothetical protein Pfl_1305 1 None None None 77458652 Nonpathogen - hypothetical protein Pfl_2427 1 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 77460207 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Pfl_3986 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 77459296 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3074 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 77460524 Common - Transcriptional Regulator, XRE family Pfl_4303 27 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 77457707 Common - Nitroreductase Pfl_1480 101 COG0778 NfnB, Nitroreductase Energy production and conversion 77456246 Common - Peptidoglycan-binding LysM Pfl_0018 45 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 77460024 Common - Haloacid dehalogenase, type II Pfl_3802 62 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 77460309 Common - ABC transporter-like Pfl_4088 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 77459458 Common - Transcriptional Regulator, GntR family Pfl_3236 138 COG1802 GntR, Transcriptional regulators Transcription 77457724 Common - aromatic amino acid aminotransferase Pfl_1497 71 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 77457526 Common - Protein of unknown function DUF477 Pfl_1299 88 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 77461439 Common - hypothetical protein Pfl_5218 22 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 77461430 Common - TraX Pfl_5209 1 None None None 77458259 Common - Integrase, catalytic region Pfl_2032 136 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 77460007 Common - Putative FecR Pfl_3785 48 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77460036 Common - extracellular solute-binding protein, family 3 Pfl_3814 128 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77460619 Common - ExsB Pfl_4398 179 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 77457268 Common - ATPase-like Pfl_1041 28 COG1106 COG1106, Predicted ATPases General function prediction only 77461044 Common coaE dephospho-CoA kinase Pfl_4823 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 77461493 Common - Cytochrome c, class II Pfl_5272 15 COG3909 COG3909, Cytochrome c556 Energy production and conversion 77461532 Common - hypothetical protein Pfl_5311 129 COG1678 COG1678, Putative transcriptional regulator Transcription 77456681 Common - Sodium/proline symporter Pfl_0453 183 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 77457866 Common - L-sorbosone dehydrogenase Pfl_1639 67 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 77460539 Common - Mg2+ transporter protein, CorA-like Pfl_4318 46 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 77460781 Common - hypothetical protein Pfl_4560 6 None None None 77457970 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase Pfl_1743 155 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 77456472 Common - cystine transporter subunit Pfl_0244 191 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77460272 Common - Polysaccharide biosynthesis protein CapD Pfl_4051 151 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77457242 Common - General substrate transporter Pfl_1015 138 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 77457004 Common - hypothetical protein Pfl_0777 168 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 77456364 Common - Type I secretion membrane fusion protein, HlyD Pfl_0136 131 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77461148 Common - hypothetical protein Pfl_4927 2 None None None 77459061 Common - Glycosyl transferase, family 39 Pfl_2836 23 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 77457993 Common - aconitate hydratase Pfl_1766 223 COG1048 AcnA, Aconitase A Energy production and conversion 77459708 Common - hypothetical protein Pfl_3486 1 None None None 77460342 Common - Transcriptional Regulator, IclR family Pfl_4121 116 COG1414 IclR, Transcriptional regulator Transcription 77457519 Common - General substrate transporter Pfl_1292 153 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461863 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Pfl_5643 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77456917 Common - Exodeoxyribonuclease V, beta subunit Pfl_0689 223 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 77461684 Common - Ppx/GppA phosphatase Pfl_5463 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 77459872 Common - OmpA/MotB Pfl_3650 145 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 77458804 Common - AFG1-like ATPase Pfl_2579 97 COG1485 COG1485, Predicted ATPase General function prediction only 77459072 Common - hypothetical protein Pfl_2847 1 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 77457572 Nonpathogen - lipoprotein, putative Pfl_1345 1 None None None 77461194 Common nadD nicotinic acid mononucleotide adenyltransferase Pfl_4973 179 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 77457249 Common rplS 50S ribosomal protein L19 Pfl_1022 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 77458082 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_1855 119 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77458299 Common - Transcriptional Regulator, LysR family Pfl_2072 145 COG0583 LysR, Transcriptional regulator Transcription 77458800 Common - extracellular solute-binding protein, family 1 Pfl_2575 129 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77461701 Common - Possible CheA Signal Transduction Histidine Kinases (STHK) Pfl_5480 1 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 77458662 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_2437 25 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77460530 Common - Protein of unknown function DUF1003 Pfl_4309 41 COG4420 COG4420, Predicted membrane protein Function unknown 77460319 Common mnmC 5-methylaminomethyl-2-thiouridine methyltransferase Pfl_4098 82 COG4121 COG4121, Uncharacterized conserved protein Function unknown 77460083 Common - soluble pyridine nucleotide transhydrogenase Pfl_3862 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 77458156 Common - Cold shock protein capA Pfl_1929 181 COG1278 CspC, Cold shock proteins Transcription 77460448 Common - thioredoxin, putative Pfl_4227 130 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77460088 Common - hypothetical protein Pfl_3867 2 None None None 77461792 Common - hypothetical protein Pfl_5571 108 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 77456328 Common - Protein of unknown function DUF1458 Pfl_0100 42 COG3360 COG3360, Uncharacterized conserved protein Function unknown 77456241 Common - hypothetical protein Pfl_0013 13 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 77458061 Common - Abortive infection protein Pfl_1834 13 None None None 77461038 Common - hypothetical protein Pfl_4817 7 None None None 77458838 Common - Ku Pfl_2613 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 77456994 Common carB carbamoyl phosphate synthase large subunit Pfl_0767 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 77458786 Nonpathogen - hypothetical protein Pfl_2561 1 None None None 77459846 Common - Two component Heavy metal response Transcriptional regulator, Winged helix family Pfl_3624 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77459701 Nonpathogen - hypothetical protein Pfl_3479 1 None None None 77458113 Common - Heat shock protein Hsp70 Pfl_1886 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 77458283 Common - N-formylglutamate amidohydrolase Pfl_2056 39 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 77458707 Common - Membrane protein involved in aromatic hydrocarbon degradation Pfl_2482 84 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 77461741 Common - xanthine phosphoribosyltransferase Pfl_5520 116 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 77457420 Common - virulence protein Pfl_1193 19 COG3946 VirJ, Type IV secretory pathway, VirJ component Intracellular trafficking and secretion 77461669 Common - Colicin immunity protein/pyocin immunity protein Pfl_5448 7 None None None 77459276 Common - UbiE/COQ5 methyltransferase Pfl_3054 46 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77457046 Nonpathogen - hypothetical protein Pfl_0819 1 None None None 77461785 Common - hypothetical protein Pfl_5564 4 None None None 77459785 Common - hypothetical protein Pfl_3563 30 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 77457889 Common - Major facilitator superfamily MFS_1 Pfl_1662 79 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77459085 Common - HPP Pfl_2860 55 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 77459606 Common - Allergen V5/Tpx-1-like Pfl_3384 68 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 77460767 Common - Transcriptional Regulator, LysR family Pfl_4546 170 COG0583 LysR, Transcriptional regulator Transcription 77461656 Common - hypothetical protein Pfl_5435 40 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 77456687 Common - methionine sulfoxide reductase A Pfl_0459 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 77460390 Common - Twin-arginine translocation pathway signal Pfl_4169 115 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 77461575 Common - hypothetical protein Pfl_5354 135 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 77459474 Common - putative lipoprotein Pfl_3252 7 None None None 77458129 Common - amidophosphoribosyltransferase Pfl_1902 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 77460687 Common - ABC transporter-like Pfl_4466 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77457802 Common - FlhB domain protein Pfl_1575 100 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 77458291 Common - Lysine-arginine-ornithine-binding periplasmic protein Pfl_2064 176 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77456623 Common - Protein of unknown function DUF971 Pfl_0395 50 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 77459402 Common - General secretion pathway protein I Pfl_3180 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77456746 Common - hypothetical protein Pfl_0518 221 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 77457423 Common - lipoprotein, putative Pfl_1196 1 None None None 77458913 Common - Protein of unknown function DUF903 Pfl_2688 2 None None None 77456988 Common - DNA repair protein RecN Pfl_0761 199 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 77458679 Common - Beta-lactamase-like Pfl_2454 87 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77460981 Common - Colicin immunity protein/pyocin immunity protein Pfl_4760 8 None None None 77457912 Common - hypothetical protein Pfl_1685 19 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 77457429 Common dcd deoxycytidine triphosphate deaminase Pfl_1202 151 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 77459409 Common - hypothetical protein Pfl_3187 2 None None None 77457160 Nonpathogen - hypothetical protein Pfl_0933 1 None None None 77460414 Common - Aminotransferase, class I and II Pfl_4193 221 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 77460591 Common - extracellular solute-binding protein, family 1 Pfl_4370 67 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 77459047 Common - Glycosyl transferase, family 2 Pfl_2822 169 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77460686 Common - Transcriptional Regulator, AraC family Pfl_4465 104 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77461828 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Pfl_5607 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 77457152 Common - RNA polymerase sigma factor Pfl_0925 71 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77459217 Common - hypothetical protein Pfl_2995 23 None None None 77461635 Common - ABC transporter, substrate-binding protein, aliphatic sulphonates Pfl_5414 120 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 77457390 Common - tail protein, putative Pfl_1163 10 COG3778 COG3778, Uncharacterized protein conserved in bacteria Function unknown 77458332 Common - hypothetical protein Pfl_2105 54 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 77461817 Common - ImpA-like Pfl_5596 23 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 77460872 Common - hypothetical protein Pfl_4651 22 COG5485 COG5485, Predicted ester cyclase General function prediction only 77461823 Common - Rubredoxin-type Fe(Cys)4 protein Pfl_5602 111 COG1773 COG1773, Rubredoxin Energy production and conversion 77456812 Common ureA urease subunit gamma Pfl_0584 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 77456905 Common - Possible Transcriptional Regulator, MerR family Pfl_0677 122 COG0789 SoxR, Predicted transcriptional regulators Transcription 77461106 Common - DNA repair protein RadA Pfl_4885 210 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 77457546 Common - hypothetical protein Pfl_1319 4 None None None 77456680 Common putA trifunctional transcriptional regulator/proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase Pfl_0452 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 77461203 Common - MaoC-like dehydratase Pfl_4982 85 COG2030 MaoC, Acyl dehydratase Lipid metabolism 77456839 Common - Periplasmic Sensor Hybrid Histidine Kinase Pfl_0611 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77458448 Common - Saccharopine dehydrogenase Pfl_2221 19 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 77457778 Common fliR flagellar biosynthesis protein FliR Pfl_1551 129 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 77457950 Common - Major facilitator superfamily MFS_1 Pfl_1723 81 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77457825 Common - glyoxylate carboligase Pfl_1598 221 COG3960 COG3960, Glyoxylate carboligase General function prediction only 77458857 Common - outer membrane porin Pfl_2632 9 None None None 77460078 Common - Lipoprotein releasing system, transmembrane protein, LolC/E family Pfl_3857 179 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 77456930 Common - Glucose-1-phosphate thymidylyltransferase, long form Pfl_0702 222 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 77458943 Common - Transketolase-like Pfl_2718 230 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 77459584 Common - Major facilitator superfamily MFS_1 Pfl_3362 12 None None None 77461834 Common - Phosphate transport system permease protein 2 Pfl_5613 220 COG4985 COG4985, ABC-type phosphate transport system, auxiliary component Inorganic ion transport and metabolism 77456744 Common - hypothetical protein Pfl_0516 133 COG2860 COG2860, Predicted membrane protein Function unknown 77457944 Common - hypothetical protein Pfl_1717 1 None None None 77460815 Common - 2-isopropylmalate synthase Pfl_4594 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 77460049 Common - Response regulator receiver domain protein (CheY) Pfl_3827 15 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77459758 Common - Transcriptional Regulator, TetR family Pfl_3536 41 COG1309 AcrR, Transcriptional regulator Transcription 77456589 Common - Permease for cytosine/purines, uracil, thiamine, allantoin Pfl_0361 49 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 77458482 Common - Alpha/beta hydrolase fold Pfl_2255 101 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77461818 Common - Rhs element Vgr protein Pfl_5597 55 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 77459393 Common - Filamentous haemagglutinin-like Pfl_3171 44 None None None 77456731 Common - DNA topoisomerase IV subunit A Pfl_0503 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 77458151 Common - RbsD or FucU transport Pfl_1924 44 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 77459992 Common - chemotaxis sensory transducer Pfl_3770 126 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77460665 Common - Protein of unknown function DUF58 Pfl_4444 98 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 77460459 Nonpathogen - hypothetical protein Pfl_4238 1 None None None 77459075 Common - GCN5-related N-acetyltransferase Pfl_2850 33 COG0456 RimI, Acetyltransferases General function prediction only 77458489 Common - Catalase-like Pfl_2262 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 77457558 Common - hypothetical protein Pfl_1331 6 None None None 77459818 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Pfl_3596 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 77460922 Common - Protein of unknown function DUF1043 Pfl_4701 9 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 77458152 Common - Inosine/uridine-preferring nucleoside hydrolase Pfl_1925 89 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 77459263 Common - Two Component Transcriptional Regulator, LuxR family Pfl_3041 168 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77459833 Common - NADH dehydrogenase subunit J Pfl_3611 72 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 77457271 Common - Betaine-aldehyde dehydrogenase Pfl_1044 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77459106 Common nudC NADH pyrophosphatase Pfl_2881 97 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 77460947 Common - hypothetical protein Pfl_4726 1 None None None 77460486 Common - Cytochrome c, class I Pfl_4265 54 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 77457039 Common - Binding-protein-dependent transport systems inner membrane component Pfl_0812 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 77457955 Common - acyl-CoA synthetase Pfl_1728 215 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77461919 Common - Acetamidase/Formamidase Pfl_5699 27 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 77460519 Common - hypothetical protein Pfl_4298 1 None None None 77457516 Common - Beta-lactamase Pfl_1289 75 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 77459625 Common - hypothetical protein Pfl_3403 19 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 77460040 Common - hypothetical protein Pfl_3818 3 None None None 77457586 Common - hypothetical protein Pfl_1359 1 None None None 77458500 Common - GCN5-related N-acetyltransferase Pfl_2273 38 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 77461410 Common - TonB-dependent siderophore receptor Pfl_5189 114 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 77461674 Common - CDP-6-deoxy-delta-3,4-glucoseen reductase Pfl_5453 94 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 77460680 Common - Citrate-proton symport Pfl_4459 139 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461596 Common - Protein of unknown function DUF81 Pfl_5375 132 COG0730 COG0730, Predicted permeases General function prediction only 77457512 Common - Protein of unknown function DUF479 Pfl_1285 33 COG3124 COG3124, Uncharacterized protein conserved in bacteria Function unknown 77459462 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein Pfl_3240 225 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 77459645 Common - Possible Sensor with PAS/PAC domain Pfl_3423 156 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77461092 Common - hypothetical protein Pfl_4871 21 None None None 77461422 Nonpathogen - hypothetical protein Pfl_5201 1 None None None 77457222 Common era GTP-binding protein Era Pfl_0995 240 COG1159 Era, GTPase General function prediction only 77461899 Common - hypothetical protein Pfl_5679 9 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77459739 Common - hypothetical protein Pfl_3517 14 None None None 77458898 Common - hypothetical protein Pfl_2673 1 None None None 77457400 Common - probable bacteriophage signal peptide protein Pfl_1173 1 None None None 77458440 Common - Amino acid adenylation Pfl_2213 220 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77461884 Common - hypothetical protein Pfl_5664 8 None None None 77456605 Common - ABC transporter-like Pfl_0377 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 77461397 Common - Biotin synthase Pfl_5176 183 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 77459565 Common - probable transmembrane protein Pfl_3343 55 COG3174 COG3174, Predicted membrane protein Function unknown 77458107 Common - hydrolase, putative Pfl_1880 29 COG2267 PldB, Lysophospholipase Lipid metabolism 77459021 Common - Gluconate transporter Pfl_2796 76 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 77459181 Common - Histidinol-phosphate phosphatase, putative, inositol monophosphatase Pfl_2956 181 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 77460182 Common - Molybdenum cofactor biosynthesis protein B Pfl_3961 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 77460957 Common - DNA photolyase, FAD-binding Pfl_4736 135 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 77457771 Common - Flagellar hook-length control protein Pfl_1544 33 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 77460151 Common - Periplasmic solute binding protein Pfl_3930 8 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 77458350 Common - Aldehyde dehydrogenase (NAD+) Pfl_2123 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77457186 Common - alginate biosynthesis protein Alg8 Pfl_0959 6 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77458509 Common - hypothetical protein Pfl_2282 7 None None None 77458093 Common - Pirin-like Pfl_1866 147 COG1741 COG1741, Pirin-related protein General function prediction only 77461331 Common - OsmC-like protein Pfl_5110 86 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77461892 Common - Possible Transcriptional Regulator, AsnC family Pfl_5672 155 COG1522 Lrp, Transcriptional regulators Transcription 77458213 Common - hypothetical protein Pfl_1986 8 None None None 77459247 Common - Transcriptional Regulator, XRE family Pfl_3025 26 COG1476 COG1476, Predicted transcriptional regulators Transcription 77457438 Common - ATP-dependent DNA ligase Pfl_1211 99 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 77460450 Common - Flavodoxin/nitric oxide synthase Pfl_4229 116 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 77460273 Common - Glycosyl transferase, family 2 Pfl_4052 100 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77461267 Common - Protein of unknown function DUF350 Pfl_5046 25 COG3766 COG3766, Predicted membrane protein Function unknown 77456723 Common - Nucleoside diphosphate pyrophosphatase Pfl_0495 127 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 77457635 Common - hypothetical protein Pfl_1408 59 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 77461238 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein Pfl_5017 226 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 77460700 Common - Drug resistance transporter EmrB/QacA subfamily Pfl_4479 232 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77456577 Common - Glycogen/starch/alpha-glucan phosphorylase Pfl_0349 143 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 77457832 Common - Glycoside hydrolase, family 17 Pfl_1605 15 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 77461654 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase Pfl_5433 113 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 77456468 Common - Acyl-CoA dehydrogenase-like Pfl_0240 128 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77456738 Common - Rhodanese-like Pfl_0510 141 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 77459691 Common - Radical SAM Pfl_3469 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 77459123 Common - hypothetical protein Pfl_2898 1 None None None 77457861 Common - hypothetical protein Pfl_1634 19 COG3249 COG3249, Uncharacterized protein conserved in bacteria Function unknown 77457932 Common - hypothetical protein Pfl_1705 43 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 77456674 Common - potassium/proton antiporter Pfl_0446 145 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 77460507 Common - Leucine-rich repeat Pfl_4286 15 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 77458922 Common - Twin-arginine translocation pathway signal Pfl_2697 173 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 77457614 Common - hypothetical protein Pfl_1387 62 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 77460368 Common - Molybdenum cofactor synthesis-like Pfl_4147 200 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 77461027 Common - hypothetical protein Pfl_4806 4 None None None 77461874 Common - hypothetical protein Pfl_5654 15 None None None 77460853 Nonpathogen - hypothetical protein Pfl_4632 1 None None None 77461503 Common - extracellular solute-binding protein, family 3 Pfl_5282 41 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77457479 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Pfl_1252 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77458562 Common - NLPA lipoprotein Pfl_2335 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 77461935 Nonpathogen - hypothetical protein Pfl_5717 1 None None None 77459883 Common - hypothetical protein Pfl_3661 1 None None None 77460145 Common - hypothetical protein Pfl_3924 5 None None None 77459278 Common - Antibiotic biosynthesis monooxygenase Pfl_3056 8 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 77457613 Common - Major facilitator superfamily MFS_1 Pfl_1386 71 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 77459342 Common - extracellular solute-binding protein, family 5 Pfl_3120 114 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 77459056 Common - hypothetical protein Pfl_2831 65 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 77461540 Common - hypothetical protein Pfl_5319 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 77457686 Common - DTW Pfl_1459 40 COG3148 COG3148, Uncharacterized conserved protein Function unknown 77458135 Common - Protein of unknown function DUF182 Pfl_1908 108 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 77460915 Common rplM 50S ribosomal protein L13 Pfl_4694 229 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 77459980 Common - Purine nucleoside permease Pfl_3758 11 COG5042 NUP, Purine nucleoside permease Nucleotide transport and metabolism 77457409 Common - Two Component Transcriptional Regulator, LuxR family Pfl_1182 195 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77457193 Common - Molybdopterin biosynthesis MoaE Pfl_0966 157 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 77460300 Common mtnA methylthioribose-1-phosphate isomerase Pfl_4079 130 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 77459368 Common - cytosine deaminase Pfl_3146 68 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 77458464 Common - Transcriptional Regulator, AraC family Pfl_2237 108 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77461927 Common - Cytochrome c biogenesis protein, transmembrane region Pfl_5707 128 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 77457497 Common - Intradiol ring-cleavage dioxygenase Pfl_1270 52 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 77458011 Common - Response regulator receiver (CheY) and ANTAR domain protein Pfl_1784 98 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 77458767 Common - LmbE-like protein Pfl_2542 24 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 77461175 Common lnt apolipoprotein N-acyltransferase Pfl_4954 164 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 77459987 Common - Protein of unknown function DUF606 Pfl_3765 11 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 77458816 Common - hypothetical protein Pfl_2591 1 None None None 77457980 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Pfl_1753 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77460327 Common - short chain dehydrogenase Pfl_4106 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 77457011 Common - hypothetical protein Pfl_0784 1 None None None 77458063 Common - Transcriptional Regulator, AraC family Pfl_1836 138 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77460819 Common - Pyrrolo-quinoline quinone Pfl_4598 111 COG1520 COG1520, FOG: WD40-like repeat Function unknown 77460934 Common - hypothetical protein Pfl_4713 75 COG2119 COG2119, Predicted membrane protein Function unknown 77461221 Common - Alpha-2-macroglobulin-like Pfl_5000 69 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 77461375 Common - Tryptophan 2-monooxygenase Pfl_5154 18 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 77456822 Common - TonB-dependent siderophore receptor Pfl_0594 121 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 77458514 Nonpathogen - hypothetical protein Pfl_2287 1 None None None 77461154 Common - Aldehyde dehydrogenase (NAD+) Pfl_4933 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77458109 Common - Dihydrouridine synthase, DuS Pfl_1882 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 77458880 Common - Fusaric acid resistance protein conserved region Pfl_2655 27 COG1289 COG1289, Predicted membrane protein Function unknown 77459855 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3633 139 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 77456823 Common - hypothetical protein Pfl_0595 72 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 77461747 Common - D-amino acid dehydrogenase small subunit Pfl_5526 142 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77458396 Common - hypothetical protein Pfl_2169 73 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 77456901 Common - Basic membrane lipoprotein Pfl_0673 100 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 77461799 Common - hypothetical protein Pfl_5578 48 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 77461946 Common atpC F0F1 ATP synthase subunit epsilon Pfl_5729 152 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 77458574 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_2347 188 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 77457298 Common - Peptidase M22, glycoprotease Pfl_1071 185 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 77459099 Common - Tat-translocated enzyme Pfl_2874 37 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 77460954 Common - hypothetical protein Pfl_4733 11 None None None 77458450 Common - putative glutathione S-transferase YghU Pfl_2223 97 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77459632 Common - Protein of unknown function DUF879 Pfl_3410 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 77459001 Common - hypothetical protein Pfl_2776 2 None None None 77460287 Common - Acyltransferase 3 Pfl_4066 11 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 77457278 Common - Protein of unknown function DUF533 Pfl_1051 34 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 77460821 Common hisS histidyl-tRNA synthetase Pfl_4600 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77456719 Common - Type I secretion outer membrane protein, TolC Pfl_0491 150 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77459135 Common - General substrate transporter Pfl_2910 109 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77457472 Common livG leucine/isoleucine/valine transporter ATP-binding subunit Pfl_1245 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 77457063 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A Pfl_0836 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 77457283 Common - CheA Signal Transduction Histidine Kinases (STHK) Pfl_1056 223 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 77457750 Common - NeuB Pfl_1523 77 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 77459303 Common - hypothetical protein Pfl_3081 1 None None None 77457021 Common - PfkB Pfl_0794 112 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 77460242 Common - TatD-like deoxyribonuclease Pfl_4021 232 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 77460921 Common - hypothetical protein Pfl_4700 76 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 77459737 Common - BFD-like (2Fe-2S)-binding region Pfl_3515 79 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 77456444 Common - TonB-dependent receptor Pfl_0216 101 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77456429 Common - Protein of unknown function DUF336 Pfl_0201 12 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 77457077 Common - hypothetical protein Pfl_0850 3 None None None 77458956 Common - Carbonate dehydratase Pfl_2731 154 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 77456842 Common fis DNA-binding protein Fis Pfl_0614 93 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 77459183 Common - Heme exporter protein D Pfl_2958 8 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 77457715 Common - Sua5/YciO/YrdC/YwlC Pfl_1488 225 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 77457285 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_1058 210 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77458953 Common - Transcriptional Regulator, LysR family Pfl_2728 176 COG0583 LysR, Transcriptional regulator Transcription 77456587 Common - Protein of unknown function DUF886 Pfl_0359 41 COG3758 COG3758, Uncharacterized protein conserved in bacteria Function unknown 77456960 Common - GCN5-related N-acetyltransferase Pfl_0732 110 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 77457891 Common - C4-dicarboxylate transporter/malic acid transport protein Pfl_1664 32 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 77459008 Common - Short-chain dehydrogenase/reductase SDR Pfl_2783 224 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 77459600 Common - hypothetical protein Pfl_3378 1 None None None 77460055 Common - Polysaccharide export protein Pfl_3833 96 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 77460836 Common - RNA methyltransferase TrmH, group 1 Pfl_4615 157 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 77460741 Common - ribonuclease T Pfl_4520 63 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 77459921 Common - Tetrahydrofolate dehydrogenase/cyclohydrolase Pfl_3699 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 77459627 Common - hypothetical protein Pfl_3405 3 None None None 77459917 Common - Peptidase S16, ATP-dependent protease La Pfl_3695 211 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 77456430 Common - Two component Heavy metal response Transcriptional regulator, Winged helix family Pfl_0202 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77459120 Common - Protein of unknown function DUF1345 Pfl_2895 41 COG4291 COG4291, Predicted membrane protein Function unknown 77459799 Common - DsrH like protein Pfl_3577 1 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 77461022 Common - Rieske (2Fe-2S) region Pfl_4801 39 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 77459236 Common - hypothetical protein Pfl_3014 4 None None None 77457942 Common folE GTP cyclohydrolase I Pfl_1715 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 77457138 Common - Fumarylacetoacetase Pfl_0911 56 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 77461910 Common - Glutathione S-transferase-like Pfl_5690 100 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77459875 Common - Transcriptional Regulator, MerR family Pfl_3653 125 COG0789 SoxR, Predicted transcriptional regulators Transcription 77460180 Nonpathogen - hypothetical protein Pfl_3959 1 None None None 77457949 Common - chorismate synthase Pfl_1722 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 77459345 Common - hypothetical protein Pfl_3123 5 COG5642 COG5642, Uncharacterized conserved protein Function unknown 77457448 Common - OmpA/MotB Pfl_1221 170 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77458941 Common - Short-chain dehydrogenase/reductase SDR Pfl_2716 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77457762 Common fliE flagellar hook-basal body protein FliE Pfl_1535 92 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 77456292 Common katE hydroperoxidase II Pfl_0064 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 77457132 Common - Protein of unknown function DUF1302 Pfl_0905 18 None None None 77459331 Common - hypothetical protein Pfl_3109 10 None None None 77460226 Common - 5-nucleotidase Pfl_4005 30 None None None 77459982 Common - hypothetical protein Pfl_3760 12 COG4317 COG4317, Uncharacterized protein conserved in bacteria Function unknown 77461409 Common - Putative FecR Pfl_5188 46 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77460607 Common - arginine deiminase Pfl_4386 53 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 77458557 Common - RHS protein Pfl_2330 66 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 77461383 Common - Peptidase S9, prolyl oligopeptidase active site region Pfl_5162 106 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 77459579 Common - Transcriptional Regulator, LysR family Pfl_3357 143 COG0583 LysR, Transcriptional regulator Transcription 77458677 Common - Response regulator receiver domain protein (CheY) Pfl_2452 116 COG4566 TtrR, Response regulator Signal transduction mechanisms 77460575 Common - acyl-CoA synthetase Pfl_4354 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77457784 Nonpathogen - hypothetical protein Pfl_1557 1 None None None 77456398 Common - Transcriptional Regulator, MarR family Pfl_0170 73 COG1846 MarR, Transcriptional regulators Transcription 77460900 Common - Penicillin-binding protein, transpeptidase Pfl_4679 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 77456808 Common ureC urease subunit alpha Pfl_0580 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 77456391 Common - Aspartyl/Asparaginyl beta-hydroxylase Pfl_0163 13 COG3555 COG3555, Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases Posttranslational modification, protein turnover, chaperones 77459633 Common - Protein of unknown function DUF1305 Pfl_3411 45 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 77458628 Common - Lysine exporter protein (LYSE/YGGA) Pfl_2401 116 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77460586 Common - Aldose 1-epimerase Pfl_4365 53 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 77461316 Common - pantothenate kinase Pfl_5095 120 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 77458612 Common - Transcriptional Regulator, AraC family Pfl_2385 140 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77459914 Common - General substrate transporter Pfl_3692 120 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461555 Common - RNA polymerase factor sigma-32 Pfl_5334 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 77457852 Common - heat shock protein 90 Pfl_1625 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 77461364 Common - 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK Pfl_5143 139 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 77459989 Common - Transcriptional Regulator, LysR family Pfl_3767 140 COG0583 LysR, Transcriptional regulator Transcription 77461776 Common - MotA/TolQ/ExbB proton channel Pfl_5555 126 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 77457459 Nonpathogen - hypothetical protein Pfl_1232 1 None None None 77460834 Common - Transcriptional Regulator, BadM/Rrf2 family Pfl_4613 173 COG1959 COG1959, Predicted transcriptional regulator Transcription 77456631 Common - Malic enzyme, NAD-binding Pfl_0403 202 COG0281 SfcA, Malic enzyme Energy production and conversion 77457033 Common - Binding-protein-dependent transport systems inner membrane component Pfl_0806 133 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 77457769 Common - Response regulator receiver domain protein (CheY) Pfl_1542 223 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 77456906 Common - hypothetical protein Pfl_0678 4 None None None 77461406 Common - Cyclic nucleotide-binding (cNMP-BD) protein Pfl_5185 100 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 77459659 Common - Alkylhydroperoxidase AhpD core Pfl_3437 73 COG2128 COG2128, Uncharacterized conserved protein Function unknown 77460632 Common aspS aspartyl-tRNA synthetase Pfl_4411 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77457652 Common - Protein of unknown function DUF482 Pfl_1425 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 77459338 Common - Sterol-binding Pfl_3116 20 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 77459713 Nonpathogen - hypothetical protein Pfl_3491 1 None None None 77458995 Common - Transcriptional Regulator, TetR family Pfl_2770 30 COG1309 AcrR, Transcriptional regulator Transcription 77459389 Common - Transcriptional Regulator, AraC family Pfl_3167 84 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77461273 Common - Bacterioferritin Pfl_5052 99 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 77456371 Common - Secretion protein HlyD Pfl_0143 154 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77456952 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pfl_0724 22 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 77459950 Common - GCN5-related N-acetyltransferase Pfl_3728 28 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 77460015 Common - Secretion protein HlyD Pfl_3793 121 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77456660 Common - Thioesterase superfamily Pfl_0432 49 COG0824 FcbC, Predicted thioesterase General function prediction only 77456562 Common - Rhodanese-like Pfl_0334 112 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 77461800 Common - Protein of unknown function DUF876 Pfl_5579 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 77459570 Common - Cytochrome B561 Pfl_3348 82 COG3038 CybB, Cytochrome B561 Energy production and conversion 77459487 Common - Alpha/beta hydrolase fold Pfl_3265 180 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77461265 Common - phage shock protein A, PspA Pfl_5044 38 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 77456676 Common - hypothetical protein Pfl_0448 1 None None None 77460828 Common - Ferredoxin, 2Fe-2S type Pfl_4607 68 COG0633 Fdx, Ferredoxin Energy production and conversion 77461372 Common - UBA/THIF-type NAD/FAD binding fold Pfl_5151 210 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 77456548 Common - A/G-specific adenine glycosylase MutY Pfl_0320 220 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 77461751 Common - hypothetical protein Pfl_5530 2 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 77460817 Common - putative aminotransferase Pfl_4596 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 77457592 Common - Peptidase S1C, Do Pfl_1365 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 77459933 Common - Protein of unknown function DUF480 Pfl_3711 41 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 77460434 Common - 3-oxoacyl-(acyl carrier protein) synthase I Pfl_4213 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77460713 Common - Secretion protein HlyD Pfl_4492 176 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77457503 Common - Trans-aconitate 2-methyltransferase Pfl_1276 75 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 77459032 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_2807 172 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77458089 Common - hypothetical protein Pfl_1862 1 None None None 77461201 Common - LrgB-like protein Pfl_4980 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 77459196 Common - hypothetical protein Pfl_2971 10 None None None 77461035 Common - acetyl-CoA synthetase Pfl_4814 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 77457990 Common - Transcriptional Regulator, GntR family Pfl_1763 141 COG1802 GntR, Transcriptional regulators Transcription 77460192 Common - hypothetical protein Pfl_3971 1 None None None 77456570 Common - hypothetical protein Pfl_0342 8 None None None 77457418 Common - hypothetical protein Pfl_1191 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 77457873 Common - cobyric acid synthase Pfl_1646 153 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 77461679 Common - GntR-like Pfl_5458 99 COG2186 FadR, Transcriptional regulators Transcription 77460237 Common - Protein of unknown function DUF214 Pfl_4016 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 77461825 Common ubiA 4-hydroxybenzoate octaprenyltransferase Pfl_5604 196 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 77456889 Common - Copper-translocating P-type ATPase Pfl_0661 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 77456345 Common - Acyl-CoA dehydrogenase-like Pfl_0117 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77461852 Common - extracellular solute-binding protein, family 1 Pfl_5632 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77457412 Common - Oxidoreductase FAD/NAD(P)-binding Pfl_1185 107 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 77456299 Common - protoheme IX farnesyltransferase Pfl_0071 171 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 77459424 Common - regulatory protein GntR, HTH Pfl_3202 197 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 77459609 Common - Oxidoreductase alpha (molybdopterin) subunit Pfl_3387 173 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 77456764 Common - hypothetical protein Pfl_0536 10 None None None 77458033 Common - hypothetical protein Pfl_1806 67 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 77460423 Common - Alpha/beta hydrolase fold Pfl_4202 140 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77460769 Common - Lysine exporter protein (LYSE/YGGA) Pfl_4548 104 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77459762 Common - YceI Pfl_3540 103 COG2353 COG2353, Uncharacterized conserved protein Function unknown 77457814 Common - hypothetical protein Pfl_1587 31 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 77459906 Common - Phosphonoacetaldehyde hydrolase Pfl_3684 47 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 77456832 Common - Nitrite and sulphite reductase 4Fe-4S region Pfl_0604 96 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 77458823 Common - hypothetical protein Pfl_2598 1 None None None 77456307 Common - Cytochrome c oxidase, subunit II Pfl_0079 157 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 77459720 Common - hypothetical protein Pfl_3498 5 None None None 77456665 Common - hypothetical protein Pfl_0437 31 COG4648 COG4648, Predicted membrane protein Function unknown 77456317 Common - hypothetical protein Pfl_0089 22 COG3529 COG3529, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 77457338 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase Pfl_1111 156 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 77457609 Common - hypothetical protein Pfl_1382 8 None None None 77461953 Common - F0F1 ATP synthase subunit A Pfl_5736 198 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 77457090 Common - ABC transporter-like Pfl_0863 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 77457695 Common - ATP-dependent DNA helicase RecQ Pfl_1468 223 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 77460118 Common - General substrate transporter Pfl_3897 132 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 77456310 Common - Carbonic anhydrase Pfl_0082 155 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 77458729 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pfl_2504 140 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 77457116 Common - Protein of unknown function DUF1244 Pfl_0889 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 77461327 Common - Short-chain dehydrogenase/reductase SDR Pfl_5106 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77457522 Common - YceI Pfl_1295 11 COG2353 COG2353, Uncharacterized conserved protein Function unknown 77457844 Common sucC succinyl-CoA synthetase subunit beta Pfl_1617 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 77457346 Common - CTP synthetase Pfl_1119 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 77459163 Common - Transcriptional Regulator, AraC family Pfl_2938 205 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 77461121 Nonpathogen - hypothetical protein Pfl_4900 3 None None None 77459666 Common - Transcriptional Regulator, TetR family Pfl_3444 55 COG1309 AcrR, Transcriptional regulator Transcription 77460068 Common - transaldolase B Pfl_3847 166 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 77457323 Common - hypothetical protein Pfl_1096 7 None None None 77459670 Common - Secretion protein HlyD Pfl_3448 137 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77458203 Common - hypothetical protein Pfl_1976 73 COG3391 COG3391, Uncharacterized conserved protein Function unknown 77458195 Common - Cyclic nucleotide-regulated Small Mechanosensitive ion channel Pfl_1968 189 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77461672 Common glpT sn-glycerol-3-phosphate transporter Pfl_5451 70 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77458720 Common - Alanine racemase-like Pfl_2495 13 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 77460187 Common - Glutaredoxin 2 Pfl_3966 11 None None None 77459990 Common - chemotaxis sensory transducer Pfl_3768 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77457552 Common - Protein of unknown function DUF1452 Pfl_1325 26 COG5478 COG5478, Predicted small integral membrane protein Function unknown 77461472 Common - extracellular solute-binding protein, family 3 Pfl_5251 30 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77459520 Common - Protein of unknown function DUF931 Pfl_3298 10 COG4392 COG4392, Predicted membrane protein Function unknown 77461477 Common - lyase, putative Pfl_5256 6 None None None 77459246 Common - hypothetical protein Pfl_3024 1 None None None 77458186 Common - Flavodoxin/nitric oxide synthase Pfl_1959 95 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 77461355 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase Pfl_5134 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 77456616 Common - hypothetical protein Pfl_0388 6 None None None 77458373 Common - ThiamineS Pfl_2146 47 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 77460961 Common - Protein of unknown function DUF1365 Pfl_4740 62 COG3496 COG3496, Uncharacterized conserved protein Function unknown 77457738 Common - NAD-dependent epimerase/dehydratase Pfl_1511 225 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77459062 Common - extracellular solute-binding protein, family 1 Pfl_2837 118 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 77461526 Common - chemotaxis sensory transducer Pfl_5305 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77460238 Common - GreA/GreB family elongation factor Pfl_4017 197 COG0782 GreA, Transcription elongation factor Transcription 77459928 Common - lipoprotein, putative Pfl_3706 1 None None None 77460654 Common - hypothetical protein Pfl_4433 7 COG3233 COG3233, Predicted deacetylase General function prediction only 77461604 Common - SdiA-regulated Pfl_5383 11 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 77457361 Common - DNA mismatch repair protein Pfl_1134 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 77458143 Common - Protein of unknown function DUF1654 Pfl_1916 1 None None None 77458348 Common - Peptidase C26 Pfl_2121 129 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 77461583 Common - hypothetical protein Pfl_5362 9 None None None 77459384 Common - 4Fe-4S ferredoxin, iron-sulfur binding Pfl_3162 46 COG1146 COG1146, Ferredoxin Energy production and conversion 77457903 Common - Rhs family protein Pfl_1676 74 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 77459449 Common - dihydroxy-acid dehydratase Pfl_3227 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 77457646 Common aceK bifunctional isocitrate dehydrogenase kinase/phosphatase protein Pfl_1419 29 COG4579 COG4579, Isocitrate dehydrogenase kinase/phosphatase Signal transduction mechanisms 77460748 Common - ornithine carbamoyltransferase Pfl_4527 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 77457606 Common - Glycosyl transferase, family 2 Pfl_1379 194 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77457659 Common - (Acyl-carrier protein) phosphodiesterase Pfl_1432 101 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 77458237 Common - YdjC-like protein Pfl_2010 27 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 77457981 Common - Transcriptional Regulator, LysR family Pfl_1754 172 COG0583 LysR, Transcriptional regulator Transcription 77459527 Common - extracellular solute-binding protein, family 3 Pfl_3305 22 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77458227 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_2000 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456774 Common - Azurin precursor Pfl_0546 17 COG3241 COG3241, Azurin Energy production and conversion 77460372 Common - DNA polymerase III subunit delta' Pfl_4151 216 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 77458490 Common - OsmC-like protein Pfl_2263 87 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77458681 Nonpathogen - hypothetical protein Pfl_2456 1 None None None 77457797 Common - Cobyrinic acid a,c-diamide synthase Pfl_1570 206 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77458610 Common - Peptidase U32 Pfl_2383 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 77459850 Nonpathogen - hypothetical protein Pfl_3628 1 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77457230 Common - PTS system, N-acetylglucosamine-specific IIBC component Pfl_1003 51 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 77460123 Common - Transcriptional Regulator, LysR family Pfl_3902 190 COG0583 LysR, Transcriptional regulator Transcription 77458341 Common - Protein of unknown function DUF1428 Pfl_2114 39 COG5507 COG5507, Uncharacterized conserved protein Function unknown 77458948 Common - Protein of unknown function DUF1206 Pfl_2723 14 None None None 77456538 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_0310 173 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 77457938 Common - Xanthine/uracil/vitamin C permease Pfl_1711 141 COG2252 COG2252, Permeases General function prediction only 77460503 Common - Aldehyde dehydrogenase Pfl_4282 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77461647 Common - glycine dehydrogenase Pfl_5426 173 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 77457477 Common - hypothetical protein Pfl_1250 4 None None None 77458244 Common - Glycosyl transferase, family 2 Pfl_2017 118 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77461082 Common - Polyprenyl synthetase Pfl_4861 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 77458972 Common - Acyl-CoA dehydrogenase-like Pfl_2747 132 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77460697 Common - hypothetical protein Pfl_4476 1 None None None 77461549 Common - hypothetical protein Pfl_5328 6 None None None 77458439 Common - Amino acid adenylation Pfl_2212 221 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77457965 Common - Cytochrome c, class I Pfl_1738 11 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 77459512 Common - NUDIX hydrolase Pfl_3290 60 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 77459749 Common - Isoprenylcysteine carboxyl methyltransferase Pfl_3527 35 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 77457898 Common - Peptidylprolyl isomerase, FKBP-type Pfl_1671 142 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 77460199 Common - Protein of unknown function DUF815 Pfl_3978 90 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 77461900 Common - hypothetical protein Pfl_5680 7 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77457213 Common valS valyl-tRNA synthetase Pfl_0986 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77457560 Common - Zeta toxin Pfl_1333 5 COG2108 COG2108, Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme General function prediction only 77460992 Common - hypothetical protein Pfl_4771 2 None None None 77457307 Common - Acriflavin resistance protein Pfl_1080 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77460692 Common - hypothetical protein Pfl_4471 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 77461686 Common - delta-aminolevulinic acid dehydratase Pfl_5465 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 77457354 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Pfl_1127 188 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 77459380 Common - Phycobiliprotein, putative Pfl_3158 63 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 77460966 Common - glutamate racemase Pfl_4745 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 77459416 Common - putative general secretion pathway protein C Pfl_3194 2 None None None 77456643 Common hemE uroporphyrinogen decarboxylase Pfl_0415 179 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 77459880 Common - gamma-carboxygeranoyl-CoA hydratase Pfl_3658 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77458252 Common - Sulfatase Pfl_2025 7 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 77456509 Common - Transcriptional Regulator, LysR family Pfl_0281 124 COG0583 LysR, Transcriptional regulator Transcription 77457205 Common - Cyanate transport system protein Pfl_0978 74 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 77456805 Common - Chaperone DnaJ-like Pfl_0577 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 77457909 Common - ABC transporter-like Pfl_1682 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77461297 Common rplB 50S ribosomal protein L2 Pfl_5076 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 77459118 Common - Secretion protein HlyD Pfl_2893 148 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77458119 Common - 3-isopropylmalate dehydrogenase Pfl_1892 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 77458267 Nonpathogen - hypothetical protein Pfl_2040 2 None None None 77458002 Common - Conserved TM helix Pfl_1775 10 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 161485589 Common - lipid kinase Pfl_3958 90 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 77461067 Common - hypothetical protein Pfl_4846 1 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 77456326 Common - luciferase-like Pfl_0098 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 77461005 Common - putative sulfite oxidase subunit YedY Pfl_4784 120 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 77456415 Common gabD succinate-semialdehyde dehydrogenase I Pfl_0187 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77456591 Common - Binding-protein-dependent transport systems inner membrane component Pfl_0363 215 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 77459978 Common - Outer membrane autotransporter barrel Pfl_3756 110 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 77458497 Common - Taurine dioxygenase Pfl_2270 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 77459725 Nonpathogen - hypothetical protein Pfl_3503 1 None None None 77458478 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Pfl_2251 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77459103 Common - Protein of unknown function DUF1348 Pfl_2878 49 COG3558 COG3558, Uncharacterized protein conserved in bacteria Function unknown 77461056 Common - Protein of unknown function DUF152 Pfl_4835 163 COG1496 COG1496, Uncharacterized conserved protein Function unknown 77458714 Common - Transcriptional Regulator, AsnC family Pfl_2489 118 COG1522 Lrp, Transcriptional regulators Transcription 77461908 Common - Glycosyl transferase, group 1 Pfl_5688 157 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77458983 Common - Secretion protein HlyD Pfl_2758 158 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77458872 Common - MCP methyltransferase, CheR-type Pfl_2647 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 77457743 Common - Cephalosporin hydroxylase Pfl_1516 21 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 77458455 Common - GGDEF domain protein Pfl_2228 3 None None None 77456269 Common - Nucleoside recognition Pfl_0041 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 77461846 Common aspA aspartate ammonia-lyase Pfl_5625 223 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 77456704 Common - LmbE-like protein Pfl_0476 2 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 77456502 Common - polysaccharide deacetylase family protein Pfl_0274 1 None None None 77459867 Common - Transcriptional Regulator, MarR family Pfl_3645 145 COG1846 MarR, Transcriptional regulators Transcription 77456751 Common hfq RNA-binding protein Hfq Pfl_0523 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 77460847 Nonpathogen - hypothetical protein Pfl_4626 1 None None None 77461562 Common - Alpha/beta hydrolase fold Pfl_5341 70 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 77457375 Common - Phage tail tape measure protein TP901, core region Pfl_1148 8 COG3941 COG3941, Mu-like prophage protein General function prediction only 77460884 Common - Two component Heavy metal response Transcriptional regulator, Winged helix family Pfl_4663 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77457594 Common - SirA-like Pfl_1367 100 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77458887 Common - hypothetical protein Pfl_2662 8 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 77457574 Common - Integrase, catalytic region Pfl_1347 136 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 77457757 Common fliS flagellar protein FliS Pfl_1530 80 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 77458864 Common - Binding-protein-dependent transport systems inner membrane component Pfl_2639 147 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 77457926 Nonpathogen - hypothetical protein Pfl_1699 1 None None None 77460282 Common - lipoprotein, putative Pfl_4061 3 None None None 77457052 Common - hypothetical protein Pfl_0825 1 None None None 77456289 Common - ABC transporter-like Pfl_0061 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 77457300 Common - Protein of unknown function DUF72 Pfl_1073 96 COG1801 COG1801, Uncharacterized conserved protein Function unknown 77457487 Common - hypothetical protein Pfl_1260 1 None None None 77461128 Common - Major facilitator superfamily MFS_1 Pfl_4907 181 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77460436 Common - hypothetical protein Pfl_4215 30 COG3122 COG3122, Uncharacterized protein conserved in bacteria Function unknown 77460400 Common - hypothetical protein Pfl_4179 52 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 77460790 Common - hypothetical protein Pfl_4569 3 None None None 77458812 Common - glucose-6-phosphate 1-dehydrogenase Pfl_2587 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 77456797 Common - (Acyl-carrier protein) phosphodiesterase Pfl_0569 95 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 77461218 Common - Possible phage repressor Pfl_4997 18 COG2932 COG2932, Predicted transcriptional regulator Transcription 77459221 Common - hypothetical protein Pfl_2999 15 None None None 77459083 Common - MmgE/PrpD Pfl_2858 54 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 77461165 Common - Periplasmic Sensor Hybrid Histidine Kinase Pfl_4944 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77459024 Common - Transcriptional Regulator, GntR family Pfl_2799 127 COG2188 PhnF, Transcriptional regulators Transcription 77461110 Common - Transcriptional Regulator, LuxR family Pfl_4889 48 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77457722 Common - hypothetical protein Pfl_1495 37 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461570 Common - 4Fe-4S ferredoxin, iron-sulfur binding Pfl_5349 114 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 77461303 Common - elongation factor G Pfl_5082 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 77459801 Common - hypothetical protein Pfl_3579 173 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 77461519 Common - Malonate decarboxylase gamma subunit Pfl_5298 26 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 77459205 Common - ABC transporter, transmembrane region Pfl_2980 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 77459148 Common - Glyoxalase I Pfl_2923 119 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 77458110 Common - Heat shock protein Hsp20 Pfl_1883 68 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 77458165 Common - Transcriptional Regulator, MerR family Pfl_1938 100 COG0789 SoxR, Predicted transcriptional regulators Transcription 77457263 Common - NADH:flavin oxidoreductase/NADH oxidase Pfl_1036 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77461288 Common rplE 50S ribosomal protein L5 Pfl_5067 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 77456280 Common - DSBA oxidoreductase Pfl_0052 68 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 77458931 Common - selenocysteine synthase Pfl_2706 68 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 77458436 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_2209 127 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77461930 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Pfl_5710 221 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77458771 Common - (1,4)-alpha-D-glucan 1-alpha-D-glucosylmutase Pfl_2546 99 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 77457721 Common - hypothetical protein Pfl_1494 113 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 77458401 Common - Twin-arginine translocation pathway signal Pfl_2174 95 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 77458138 Common - hypothetical protein Pfl_1911 11 COG3556 COG3556, Predicted membrane protein Function unknown 77461485 Common - hypothetical protein Pfl_5264 1 None None None 77460269 Common - ABC transporter-like Pfl_4048 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 77460386 Common - Pseudouridine synthase, RluD Pfl_4165 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 77460605 Common - Arginine/ornithine antiporter Pfl_4384 124 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 77456967 Common - hypothetical protein Pfl_0740 36 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 77460098 Common - TonB box-like Pfl_3877 36 COG4728 COG4728, Uncharacterized protein conserved in bacteria Function unknown 77457018 Common - TatD-like deoxyribonuclease Pfl_0791 235 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 77456331 Common - tryptophan synthase subunit beta Pfl_0103 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 77458386 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pfl_2159 40 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 77460256 Common - hypothetical protein Pfl_4035 1 None None None 77460725 Common - Pyridoxamine 5'-phosphate oxidase-like, FMN-binding Pfl_4504 30 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 77460150 Common - ABC-3 Pfl_3929 195 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 77460463 Common - Dienelactone hydrolase Pfl_4242 109 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 77460734 Common - Endonuclease III/Nth Pfl_4513 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 77457623 Common - hypothetical protein Pfl_1396 27 None None None 77456866 Common - TadE-like Pfl_0638 3 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 77460499 Common ribH riboflavin synthase subunit beta Pfl_4278 142 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 77456915 Common - hypothetical protein Pfl_0687 1 None None None 77460484 Common - Glucose-methanol-choline oxidoreductase Pfl_4263 82 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 77457884 Common - hypothetical protein Pfl_1657 1 None None None 77461017 Common - Cyclic nucleotide-binding (cNMP-BD) protein Pfl_4796 42 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 77461339 Common - anthranilate synthase component I Pfl_5118 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 77456543 Common - hypothetical protein Pfl_0315 1 None None None 77458042 Common - Cytochrome oxidase maturation protein cbb3-type Pfl_1815 13 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 77461345 Common - extracellular solute-binding protein, family 1 Pfl_5124 65 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77460673 Common - Fe-S type hydro-lyase tartrate/fumarate alpha region Pfl_4452 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 77457070 Common - hypothetical protein Pfl_0843 55 COG3164 COG3164, Predicted membrane protein Function unknown 77461710 Common - argininosuccinate lyase Pfl_5489 233 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 77461136 Common - HAD-superfamily hydrolase subfamily IA, variant 1 and 3 Pfl_4915 60 COG0546 Gph, Predicted phosphatases General function prediction only 77460513 Common - Lysine-arginine-ornithine-binding periplasmic protein Pfl_4292 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77458538 Common - hypothetical protein Pfl_2311 1 None None None 77459350 Common - Transcriptional Regulator, LysR family Pfl_3128 174 COG0583 LysR, Transcriptional regulator Transcription 77456524 Common - hypothetical protein Pfl_0296 35 COG4340 COG4340, Uncharacterized protein conserved in bacteria Function unknown 77456709 Common - Lipid A export ATP-binding/permease protein MsbA Pfl_0481 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 77460155 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_3934 178 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77457403 Common recX recombination regulator RecX Pfl_1176 83 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 77459641 Common - short chain dehydrogenase Pfl_3419 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77461281 Common rplO 50S ribosomal protein L15 Pfl_5060 208 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 77461443 Common - hypothetical protein Pfl_5222 85 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 77458944 Common - Transketolase-like Pfl_2719 220 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 77458573 Common - Transcriptional Regulator, XRE family with Cupin sensor domain Pfl_2346 116 COG1396 HipB, Predicted transcriptional regulators Transcription 77461192 Common - hypothetical protein Pfl_4971 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 77456892 Common - Drug resistance transporter Bcr/CflA subfamily Pfl_0664 217 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461177 Common - hypothetical protein Pfl_4956 1 None None None 77459964 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3742 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 77460898 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase Pfl_4677 209 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 77456721 Common - Permease for cytosine/purines, uracil, thiamine, allantoin Pfl_0493 19 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 77457229 Common - hypothetical protein Pfl_1002 2 None None None 77460689 Common - Binding-protein-dependent transport systems inner membrane component Pfl_4468 212 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 77459680 Common - hypothetical protein Pfl_3458 89 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 77460268 Common - hypothetical protein Pfl_4047 24 COG4627 COG4627, Uncharacterized protein conserved in bacteria Function unknown 77460212 Common - Protein of unknown function DUF1006 Pfl_3991 60 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 77456883 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Pfl_0655 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77456765 Common rplI 50S ribosomal protein L9 Pfl_0537 195 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 77458635 Common - Transcriptional Regulator, MarR family Pfl_2408 87 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 77458442 Common - hypothetical protein Pfl_2215 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 77457768 Common - Anti-Sigma-factor antagonist (STAS) Pfl_1541 13 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 77461671 Nonpathogen - hypothetical protein Pfl_5450 1 None None None 77459835 Common - NADH dehydrogenase subunit L Pfl_3613 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 77456515 Common - Two Component, Sigma-54 Specific, Transcriptional Regulator, Fis family Pfl_0287 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77458331 Common - Allergen V5/Tpx-1-like Pfl_2104 41 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 77461232 Common ribA GTP cyclohydrolase II Pfl_5011 195 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 77461770 Common gmk guanylate kinase Pfl_5549 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 77457041 Common - outer membrane porin Pfl_0814 11 None None None 77460901 Common - Cell division protein, FtsL-like Pfl_4680 35 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 77461216 Common - Protein of unknown function DUF980 Pfl_4995 57 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 77459229 Common - PilL protein Pfl_3007 21 None None None 77457732 Common flgJ peptidoglycan hydrolase Pfl_1505 71 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 77460016 Common - Drug resistance transporter EmrB/QacA subfamily Pfl_3794 187 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77460939 Common - hypothetical protein Pfl_4718 26 None None None 77456778 Common - Aldehyde dehydrogenase Pfl_0550 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77461099 Common - C4-dicarboxylate transporter DctA Pfl_4878 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 77458308 Common - hypothetical protein Pfl_2081 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 77458502 Common - NmrA-like Pfl_2275 53 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77461925 Common - hypothetical protein Pfl_5705 1 None None None 77456478 Common - TonB-dependent receptor Pfl_0250 103 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77459155 Nonpathogen - hypothetical protein Pfl_2930 1 None None None 77458178 Common - hypothetical protein Pfl_1951 95 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 77461259 Common - hypothetical protein Pfl_5038 56 COG0392 COG0392, Predicted integral membrane protein Function unknown 77461658 Common - Protein of unknown function DUF710 Pfl_5437 34 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 77458759 Common - Alpha amylase, catalytic region Pfl_2534 91 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 77460509 Common - ABC transporter-like Pfl_4288 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 77461202 Common - LrgA Pfl_4981 1 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 77457005 Common nusA transcription elongation factor NusA Pfl_0778 216 COG0195 NusA, Transcription elongation factor Transcription 77456932 Common - 6-phosphogluconate dehydrogenase, NAD-binding Pfl_0704 165 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 77457389 Common - Baseplate J-like protein Pfl_1162 25 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 77459791 Common - Chitin-binding, domain 3 Pfl_3569 27 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 77459516 Common - ABC transporter, substrate-binding protein, aliphatic sulphonates Pfl_3294 99 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 77458484 Common - Alpha/beta hydrolase fold Pfl_2257 44 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77461090 Common - ATP-dependent protease, putative Pfl_4869 102 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 77456983 Common - Sodium:neurotransmitter symporter Pfl_0756 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 77460137 Common - luciferase-like Pfl_3916 83 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 77460827 Common - Protein of unknown function DUF528 Pfl_4606 41 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 77459889 Common - Predicted transmembrane transcriptional regulator (anti-Sigma-factor) Pfl_3667 25 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 77457184 Common - Sel1-like repeat Pfl_0957 2 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 77458311 Nonpathogen - hypothetical protein Pfl_2084 3 None None None 77460813 Common xseA exodeoxyribonuclease VII large subunit Pfl_4592 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 77457673 Common - RNA binding S1 Pfl_1446 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 77458968 Common - Fumarate reductase/succinate dehydrogenase flavoprotein-like Pfl_2743 131 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77457882 Common - Membrane protein involved in aromatic hydrocarbon degradation Pfl_1655 91 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 77458047 Common - Cytochrome c oxidase cbb3-type, subunit III Pfl_1820 87 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 77461573 Common - Predicted signal transduction protein Pfl_5352 63 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 77457161 Common - Protein of unknown function DUF6, transmembrane Pfl_0934 39 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77461889 Common - Band 7 protein Pfl_5669 149 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 77459126 Common - Xylose isomerase-like TIM barrel Pfl_2901 14 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 77461876 Common - hypothetical protein Pfl_5656 3 None None None 77456553 Common - hypothetical protein Pfl_0325 12 COG5460 COG5460, Uncharacterized conserved protein Function unknown 77461207 Common - aromatic acid decarboxylase Pfl_4986 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 77457425 Common - AmpG permease Pfl_1198 104 None None None 77461667 Nonpathogen - hypothetical protein Pfl_5446 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 77459472 Nonpathogen - hypothetical protein Pfl_3250 1 None None None 77461223 Common - hypothetical protein Pfl_5002 7 COG4685 COG4685, Uncharacterized protein conserved in bacteria Function unknown 77456418 Common - Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain Pfl_0190 190 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77458467 Common - Transcriptional Regulator, LysR family Pfl_2240 188 COG0583 LysR, Transcriptional regulator Transcription 77459033 Common - lipoprotein, putative Pfl_2808 36 None None None 77456672 Common - hypothetical protein Pfl_0444 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 77456953 Common - Transcriptional Regulator, AraC family Pfl_0725 77 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77456450 Common - Response regulator receiver domain protein (CheY) Pfl_0222 169 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77457382 Common - hypothetical protein Pfl_1155 10 None None None 77456924 Common - 3-hydroxyisobutyrate dehydrogenase Pfl_0696 158 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 77457600 Common - Beta-lactamase-like Pfl_1373 61 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 77457206 Common - hypothetical protein Pfl_0979 10 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 77458475 Common - Transcriptional Regulator, Winged helix family Pfl_2248 73 COG3903 COG3903, Predicted ATPase General function prediction only 77457761 Common - Two Component, Sigma-54 Specific, Transcriptional Regulator, Fis family Pfl_1534 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77460652 Common - chemotaxis sensory transducer, Cache sensor Pfl_4431 140 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77459318 Common - magnesium chelatase subunit ChlD Pfl_3096 11 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 77459787 Common - Gamma-glutamyltranspeptidase Pfl_3565 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 77460356 Common - PfkB Pfl_4135 146 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 77457133 Common - Protein of unknown function DUF1329 Pfl_0906 17 None None None 77461546 Common - hypothetical protein Pfl_5325 13 None None None 77461859 Common - pyruvate carboxylase subunit B Pfl_5639 196 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 77459407 Nonpathogen - hypothetical protein Pfl_3185 1 None None None 77457945 Common - Isochorismatase hydrolase Pfl_1718 96 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 77458378 Common - Molybdopterin biosynthesis MoeA protein Pfl_2151 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 77458626 Common - Arsenical pump membrane protein Pfl_2399 107 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 77461819 Common - hypothetical protein Pfl_5598 4 None None None 77459104 Common - luciferase-like Pfl_2879 91 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 77460677 Common - Insecticidal toxin protein, putative Pfl_4456 51 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 77457038 Common - Binding-protein-dependent transport systems inner membrane component Pfl_0811 215 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 77461141 Common - DEAD/DEAH box helicase-like Pfl_4920 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77460321 Common - Asparagine synthase, glutamine-hydrolyzing Pfl_4100 154 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 77457523 Common - Phospholipase D/Transphosphatidylase Pfl_1296 149 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 77459363 Common - Transcriptional Regulator, GntR family Pfl_3141 123 COG1802 GntR, Transcriptional regulators Transcription 77460682 Common - hypothetical protein Pfl_4461 1 None None None 77457027 Common - Sel1-like repeat Pfl_0800 82 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 77461612 Common - 2OG-Fe(II) oxygenase Pfl_5391 30 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 77459852 Common - extracellular solute-binding protein, family 1 Pfl_3630 36 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 77460329 Common - Sulfatase Pfl_4108 65 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 77457792 Common - Chemotaxis phosphatase, CheZ Pfl_1565 45 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77457968 Common - amidotransferase Pfl_1741 145 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 77460969 Common prfA peptide chain release factor 1 Pfl_4748 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 77456229 Common dnaA chromosomal replication initiation protein Pfl_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 77459488 Common - Flavin-containing monooxygenase FMO Pfl_3266 61 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 77461492 Common - Protein of unknown function DUF1090 Pfl_5271 18 None None None 77456742 Common - ribosome-associated GTPase Pfl_0514 163 COG1162 COG1162, Predicted GTPases General function prediction only 77461619 Common - Penicillin amidase Pfl_5398 77 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 77458927 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_2702 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77461550 Common trmB tRNA (guanine-N(7))-methyltransferase Pfl_5329 176 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 77458501 Common - Cupin region Pfl_2274 21 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 77459399 Common - probable type II secretion system protein Pfl_3177 2 COG3297 PulL, Type II secretory pathway, component PulL Intracellular trafficking and secretion 77457984 Common - phosphoadenosine phosphosulfate reductase Pfl_1757 155 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 77461408 Common - RNA polymerase sigma factor Pfl_5187 71 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77460102 Common - UspA Pfl_3881 104 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 77459400 Common - General secretion pathway protein K Pfl_3178 24 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 77461290 Common rplN 50S ribosomal protein L14 Pfl_5069 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 77461556 Common - Protein of unknown function DUF214 Pfl_5335 108 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 77460471 Common flgC flagellar basal body rod protein FlgC Pfl_4250 114 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 77457616 Common - Protein of unknown function DUF709 Pfl_1389 35 COG3100 COG3100, Uncharacterized protein conserved in bacteria Function unknown 77458775 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pfl_2550 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 77458470 Common - NADH:flavin oxidoreductase/NADH oxidase Pfl_2243 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77461748 Common - Transcriptional Regulator, AsnC family Pfl_5527 161 COG1522 Lrp, Transcriptional regulators Transcription 77458712 Common - hypothetical protein Pfl_2487 132 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 77460457 Common - C4-dicarboxylate transporter DctA Pfl_4236 162 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 77460930 Common - acyl-CoA synthetase Pfl_4709 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77461123 Common - 3-dehydroquinate dehydratase Pfl_4902 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 77457562 Common - Pseudouridine synthase, Rsu Pfl_1335 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 77461074 Common - bifunctional riboflavin kinase/FMN adenylyltransferase Pfl_4853 211 COG0196 RibF, FAD synthase Coenzyme metabolism 77459261 Common - Putative diguanylate phosphodiesterase (EAL domain) with Response Regulator Receiver modulation Pfl_3039 176 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77460841 Common yajC preprotein translocase subunit YajC Pfl_4620 175 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 77459215 Common - Phage Transcriptional Regulator, AlpA Pfl_2993 31 COG3311 AlpA, Predicted transcriptional regulator Transcription 77461528 Common - Response regulator receiver domain protein (CheY) Pfl_5307 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77461814 Common - Protein of unknown function DUF1316 Pfl_5593 11 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 77456898 Common - General substrate transporter Pfl_0670 196 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77460548 Common - DGPFAETKE Pfl_4327 44 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 77461765 Common pyrE orotate phosphoribosyltransferase Pfl_5544 124 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 77460042 Nonpathogen - hypothetical protein Pfl_3820 1 None None None 77460072 Common - hypothetical protein Pfl_3851 15 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 77458915 Common - DEAD_2 Pfl_2690 98 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 77460110 Common - hypothetical protein Pfl_3889 46 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 77459453 Common - Protein of unknown function DUF1185 Pfl_3231 23 None None None 77457582 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_1355 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77458228 Common - Multicopper oxidase, type 2 Pfl_2001 41 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 77461708 Common hemC porphobilinogen deaminase Pfl_5487 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 77460387 Common - Ribonuclease E and G Pfl_4166 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 77461007 Common - ketol-acid reductoisomerase Pfl_4786 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 77458206 Common - cytochrome c, putative Pfl_1979 50 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 77460889 Common - cell division protein FtsZ Pfl_4668 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 77457632 Common - hypothetical protein Pfl_1405 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 77459995 Common - Propeptide, PepSY amd peptidase M4 Pfl_3773 9 COG3212 COG3212, Predicted membrane protein Function unknown 77456729 Common - hypothetical protein Pfl_0501 1 None None None 77460054 Common - hypothetical protein Pfl_3832 3 None None None 77457019 Common - DNA-binding transcriptional regulator FruR Pfl_0792 124 COG1609 PurR, Transcriptional regulators Transcription 77459265 Common - pili assembly chaperone Pfl_3043 28 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 77459918 Common clpX ATP-dependent protease ATP-binding subunit Pfl_3696 225 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 77460416 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_4195 119 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 77457584 Common - Glycine cleavage T protein Pfl_1357 113 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 77458856 Common - Rhs element Vgr protein Pfl_2631 51 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 77457012 Common - nicotinate-nucleotide pyrophosphorylase Pfl_0785 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 77461502 Common - 5,10-methylenetetrahydrofolate reductase Pfl_5281 144 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 77459328 Common - Fatty acid cistrans isomerase Pfl_3106 15 None None None 77459798 Common - hypothetical protein Pfl_3576 38 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 77457953 Common - 2,3-diketo-5-methylthio-1-phosphopentane phosphatase Pfl_1726 33 COG4229 COG4229, Predicted enolase-phosphatase Energy production and conversion 77458095 Common - Exodeoxyribonuclease III xth Pfl_1868 198 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 77459671 Common - Major facilitator superfamily MFS_1 Pfl_3449 69 None None None 77460777 Common - Amino acid permease-associated region Pfl_4556 188 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 77457310 Common - lipoprotein, putative Pfl_1083 31 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 77461118 Common - Xanthine/uracil/vitamin C permease Pfl_4897 134 COG2252 COG2252, Permeases General function prediction only 77461043 Common - Prepilin peptidase Pfl_4822 123 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 77459535 Common - putative monovalent cation/H+ antiporter subunit E Pfl_3313 50 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 77456539 Common - extracellular solute-binding protein, family 3 Pfl_0311 173 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77458297 Common - hypothetical protein Pfl_2070 26 None None None 77456879 Common - Response regulator receiver domain protein (CheY) Pfl_0651 51 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77457069 Common - Ribonuclease E and G Pfl_0842 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 77461415 Common - Acyltransferase 3 Pfl_5194 43 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 77459733 Common - extracellular solute-binding protein, family 1 Pfl_3511 25 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 77460978 Common - Major facilitator superfamily MFS_1 Pfl_4757 81 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77457834 Common - Protein of unknown function DUF485 Pfl_1607 52 COG3162 COG3162, Predicted membrane protein Function unknown 77460270 Common - ABC-2 Pfl_4049 119 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 77461480 Common - Fructose/tagatose bisphosphate aldolase-like Pfl_5259 141 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 77459821 Common - Transcription factor jumonji, jmjC Pfl_3599 55 COG2850 COG2850, Uncharacterized conserved protein Function unknown 77461320 Common - Peptidase M23B Pfl_5099 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 77459507 Common - Transcriptional Regulator, LysR family Pfl_3285 191 COG0583 LysR, Transcriptional regulator Transcription 77456252 Common - Sulphate transporter Pfl_0024 160 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 77457238 Common - transferase hexapeptide repeat Pfl_1011 206 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 77459599 Common - hypothetical protein Pfl_3377 25 None None None 77458664 Common - Short-chain dehydrogenase/reductase SDR Pfl_2439 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77461941 Common - Tn7-like transposition protein B Pfl_5724 46 None None None 77460204 Common - aminotransferase AlaT Pfl_3983 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 77459441 Common - hypothetical protein Pfl_3219 1 None None None 77457845 Common - succinyl-CoA synthetase subunit alpha Pfl_1618 217 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 77460086 Common - glyceraldehyde-3-phosphate dehydrogenase Pfl_3865 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 77460424 Common - Alpha/beta hydrolase fold Pfl_4203 31 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77460023 Common - hypothetical protein Pfl_3801 94 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 77458595 Common - Transcriptional Regulator, LysR family Pfl_2368 177 COG0583 LysR, Transcriptional regulator Transcription 77457314 Common - rRNA (guanine-N(1)-)-methyltransferase Pfl_1087 61 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77459848 Nonpathogen - hypothetical protein Pfl_3626 1 None None None 77456910 Common - hypothetical protein Pfl_0682 127 COG1739 COG1739, Uncharacterized conserved protein Function unknown 77461850 Common - Transcriptional Regulator, AraC family Pfl_5630 86 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77456381 Common - Rhs element Vgr protein Pfl_0153 56 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 77457972 Common - Protein of unknown function DUF74 Pfl_1745 89 COG0393 COG0393, Uncharacterized conserved protein Function unknown 77458105 Common gltX glutamyl-tRNA synthetase Pfl_1878 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 77461499 Common - transporter, formate/nitrite transporter family, putative Pfl_5278 69 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 77460277 Common - Glucose-1-phosphate thymidylyltransferase, long form Pfl_4056 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 77460445 Nonpathogen - hypothetical protein Pfl_4224 1 None None None 77456888 Common - Transcriptional Regulator, MerR family Pfl_0660 144 COG0789 SoxR, Predicted transcriptional regulators Transcription 77459911 Common - Transcriptional Regulator, AraC family Pfl_3689 74 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77461864 Common uvrD DNA-dependent helicase II Pfl_5644 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 77460794 Common - Siderophore-interacting protein Pfl_4573 63 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 77459054 Common - extracellular solute-binding protein, family 1 Pfl_2829 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77457682 Common - Permease for cytosine/purines, uracil, thiamine, allantoin Pfl_1455 31 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 77461100 Common - regulatory protein GntR, HTH Pfl_4879 137 COG2186 FadR, Transcriptional regulators Transcription 77459053 Common - Glutamine synthetase, catalytic region Pfl_2828 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 77458077 Common - Cyclic peptide transporter Pfl_1850 247 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 77456243 Common - Fmu, rRNA SAM-dependent methyltransferase Pfl_0015 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 77459468 Common - hypothetical protein Pfl_3246 22 None None None 77456685 Nonpathogen - hypothetical protein Pfl_0457 1 None None None 77459291 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Pfl_3069 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 77460249 Common - hypothetical protein Pfl_4028 1 None None None 77457348 Common eno phosphopyruvate hydratase Pfl_1121 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 77461584 Common - GTP-binding protein, HSR1-like Pfl_5363 20 COG0486 ThdF, Predicted GTPase General function prediction only 77461783 Nonpathogen - hypothetical protein Pfl_5562 1 None None None 77458780 Common - hypothetical protein Pfl_2555 1 None None None 77460600 Common - TonB-dependent haemoglobin/transferrin/lactoferrin receptor Pfl_4379 130 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77460761 Common - Two Component, Sigma-54 Specific, Transcriptional Regulator, Fis family Pfl_4540 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77459985 Nonpathogen - hypothetical protein Pfl_3763 1 None None None 77460498 Nonpathogen - hypothetical protein Pfl_4277 1 None None None 77459586 Common - DNA topoisomerase III Pfl_3364 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 77456270 Common gltP glutamate/aspartate:proton symporter Pfl_0042 160 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 77457813 Common - hypothetical protein Pfl_1586 1 None None None 77459896 Common - type 1 pili protein CsuB, putative Pfl_3674 11 COG5430 COG5430, Uncharacterized secreted protein Function unknown 77460784 Nonpathogen - hypothetical protein Pfl_4563 1 None None None 77458727 Common - hypothetical protein Pfl_2502 6 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77461634 Common - alkanesulfonate monooxygenase Pfl_5413 87 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 77459874 Common - Transcriptional Regulator, LysR family Pfl_3652 142 COG0583 LysR, Transcriptional regulator Transcription 77459897 Common - AFG1-like ATPase Pfl_3675 98 COG1485 COG1485, Predicted ATPase General function prediction only 77458902 Common - extracellular solute-binding protein, family 1 Pfl_2677 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77460405 Common fadE acyl-CoA dehydrogenase Pfl_4184 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77456977 Common - Protein of unknown function DUF162 Pfl_0750 68 COG1556 COG1556, Uncharacterized conserved protein Function unknown 77460449 Common - Arsenate reductase Pfl_4228 112 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 77456783 Common - ABC transporter-like Pfl_0555 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 77459349 Common - Enoyl-CoA hydratase/isomerase Pfl_3127 33 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 77461448 Common - hypothetical protein Pfl_5227 11 None None None 77458673 Common - Cytochrome c, class I Pfl_2448 54 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 77459905 Common - Regulator of chromosome condensation, RCC1 Pfl_3683 166 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 77458123 Common truA tRNA pseudouridine synthase A Pfl_1896 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 77460333 Common - regulatory protein GntR, HTH Pfl_4112 222 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 77460643 Common - 2-dehydropantoate 2-reductase Pfl_4422 100 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 77458284 Common - Glutamine synthetase, catalytic region Pfl_2057 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 77460768 Common - GCN5-related N-acetyltransferase Pfl_4547 48 COG0456 RimI, Acetyltransferases General function prediction only 77461847 Common - Sodium:alanine symporter Pfl_5626 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 77460316 Common - hypothetical protein Pfl_4095 1 None None None 77456942 Common - NAD(P)H dehydrogenase (quinone) Pfl_0714 69 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 77458357 Common - ISPsy11, transposase OrfA Pfl_2130 9 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 77456361 Common - von Willebrand factor, type A Pfl_0133 93 None None None 77458273 Common - Protein of unknown function DUF1338 Pfl_2046 23 COG5383 COG5383, Uncharacterized protein conserved in bacteria Function unknown 77457548 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pfl_1321 18 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 77456853 Common - NUDIX hydrolase Pfl_0625 33 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 77459049 Common - UDP-glucose 4-epimerase Pfl_2824 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 77458761 Common - glycogen branching enzyme Pfl_2536 147 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 77459235 Common - hypothetical protein Pfl_3013 22 None None None 77461535 Common pyrB aspartate carbamoyltransferase catalytic subunit Pfl_5314 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 77459973 Common - delta-aminolevulinic acid dehydratase Pfl_3751 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 77456386 Nonpathogen - hypothetical protein Pfl_0158 1 None None None 77459494 Common - Isochorismatase hydrolase Pfl_3272 112 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 77459000 Common - Transcriptional Regulator, LysR family Pfl_2775 167 COG0583 LysR, Transcriptional regulator Transcription 77458809 Common - hypothetical protein Pfl_2584 67 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 77458070 Common - Transcription factor jumonji, jmjC Pfl_1843 21 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 77456707 Common - Acyltransferase 3 Pfl_0479 59 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 77458279 Common - carboxyphosphonoenolpyruvate phosphonomutase, putative Pfl_2052 111 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 77460166 Common - Protein of unknown function DUF1446 Pfl_3945 35 None None None 77459092 Common - Acyl-CoA dehydrogenase-like Pfl_2867 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77459298 Common - ABC transporter-like Pfl_3076 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 77459172 Common - hypothetical protein Pfl_2947 1 None None None 77459703 Common - hypothetical protein Pfl_3481 6 None None None 77459944 Common - Transcriptional Regulator, LysR family Pfl_3722 135 COG0583 LysR, Transcriptional regulator Transcription 77458361 Common - Putative ammonia monooxygenase Pfl_2134 17 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 77456274 Common - Two Component, Sigma-54 Specific, Transcriptional Regulator, Fis family Pfl_0046 218 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77458427 Common - Peptidase M, neutral zinc metallopeptidase, zinc-binding site Pfl_2200 157 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 77459544 Nonpathogen - hypothetical protein Pfl_3322 1 None None None 77461760 Common radC DNA repair protein RadC Pfl_5539 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 77457251 Common - Sodium/hydrogen exchanger Pfl_1024 136 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 77461021 Common - Periplasmic binding protein Pfl_4800 93 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 77460557 Common - Carbohydrate kinase, thermoresistant glucokinase Pfl_4336 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 77456530 Common - Short-chain dehydrogenase/reductase SDR Pfl_0302 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77457539 Common - Major facilitator superfamily MFS_1 Pfl_1312 226 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461949 Common - F0F1 ATP synthase subunit alpha Pfl_5732 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 77457567 Common - hypothetical protein Pfl_1340 46 COG3665 COG3665, Uncharacterized conserved protein Function unknown 77461455 Common - Gamma-butyrobetaine hydroxylase Pfl_5234 7 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 77457645 Common - chemotaxis sensory transducer Pfl_1418 132 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77460263 Common - Glycosyl transferase, family 2 Pfl_4042 181 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77458645 Common - Transcriptional Regulator, LysR family Pfl_2420 162 COG0583 LysR, Transcriptional regulator Transcription 77457818 Common - Thiosulphate-binding protein Pfl_1591 91 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 77457530 Common - Peptidase C56, PfpI Pfl_1303 143 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 77460533 Common - Antibiotic biosynthesis monooxygenase Pfl_4312 26 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 77457231 Common - Phosphoenolpyruvate-protein phosphotransferase Pfl_1004 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 77456248 Common - SUA5/yciO/yrdC-like Pfl_0020 237 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 77459483 Common - Permease for cytosine/purines, uracil, thiamine, allantoin Pfl_3261 52 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 77457808 Common - cytochrome c-type biogenesis protein CcmE Pfl_1581 94 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 77458324 Common ligD ATP-dependent DNA ligase Pfl_2097 98 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 77461718 Nonpathogen - lipoprotein LppL Pfl_5497 1 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 77458414 Common - DNA polymerase III subunit epsilon Pfl_2187 184 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 77459013 Common - Manganese containing catalase Pfl_2788 47 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 77456584 Common - lipoprotein Blc Pfl_0356 74 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 77458318 Common - hypothetical protein Pfl_2091 9 None None None 77456325 Common - OsmC-like protein Pfl_0097 91 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77457365 Nonpathogen - hypothetical protein Pfl_1138 1 None None None 77457277 Common - Transcriptional Regulator, LysR family Pfl_1050 192 COG0583 LysR, Transcriptional regulator Transcription 77460752 Common - Aquaporin Pfl_4531 134 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 77460005 Common - trypsin domain protein Pfl_3783 3 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 77456712 Common - bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase Pfl_0484 180 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 77460375 Common - 4-amino-4-deoxychorismate lyase Pfl_4154 185 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 77459375 Common - Transcriptional Regulator, LysR family Pfl_3153 189 COG0583 LysR, Transcriptional regulator Transcription 77460307 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Pfl_4086 181 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77460916 Common - Aldo/keto reductase Pfl_4695 197 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 77461199 Nonpathogen - hypothetical protein Pfl_4978 1 None None None 77456432 Nonpathogen - Transcriptional Regulator, XRE family Pfl_0204 1 COG1396 HipB, Predicted transcriptional regulators Transcription 77458706 Common - Transcriptional Regulator, TetR family Pfl_2481 61 COG1309 AcrR, Transcriptional regulator Transcription 77459461 Common - Protein of unknown function DUF1330 Pfl_3239 44 COG5470 COG5470, Uncharacterized conserved protein Function unknown 77460749 Common - ABC transporter-like Pfl_4528 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77460566 Common - Sigma-24 (FecI) Pfl_4345 35 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77458580 Common - hypothetical protein Pfl_2353 4 None None None 77456639 Common aroB 3-dehydroquinate synthase Pfl_0411 206 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 77461466 Common - Peptidase U62, modulator of DNA gyrase Pfl_5245 166 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 77460993 Common - hypothetical protein Pfl_4772 5 COG2940 COG2940, Proteins containing SET domain General function prediction only 77458772 Common - 4-alpha-glucanotransferase Pfl_2547 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 77460381 Common rpmF 50S ribosomal protein L32 Pfl_4160 95 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 77457828 Common - Protein of unknown function DUF808 Pfl_1601 61 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 77459142 Common - 4-hydroxyphenylpyruvate dioxygenase Pfl_2917 78 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 77460431 Common - hypothetical protein Pfl_4210 11 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 77457055 Common - Aldehyde dehydrogenase Pfl_0828 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77459026 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_2801 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77458867 Common - hypothetical protein Pfl_2642 5 None None None 77458933 Common - outer membrane porin Pfl_2708 7 None None None 77461010 Common - hypothetical protein Pfl_4789 4 None None None 77459115 Common - acetyltransferase, GNAT family Pfl_2890 13 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 77460196 Common - Multi-sensor Hybrid Histidine Kinase Pfl_3975 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456419 Common - Fatty acid desaturase Pfl_0191 65 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 77460133 Common - Aromatic amino acid beta-eliminating lyase/threonine aldolase Pfl_3912 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 77457691 Common - Protein of unknown function DUF454 Pfl_1464 3 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 77460403 Common - Glutathione S-transferase-like Pfl_4182 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77460363 Common - short chain dehydrogenase Pfl_4142 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77460245 Common - acyl-CoA thioesterase II, putative Pfl_4024 11 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 77458051 Common - Cytochrome c oxidase cbb3-type, subunit III Pfl_1824 89 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 77459199 Common - Radical SAM Pfl_2974 95 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 77459811 Common infA translation initiation factor IF-1 Pfl_3589 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 77457200 Common - extracellular solute-binding protein, family 3 Pfl_0973 107 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77457674 Common - hypothetical protein Pfl_1447 28 COG4852 COG4852, Predicted membrane protein Function unknown 77457265 Common mdoD glucan biosynthesis protein D Pfl_1038 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 77458517 Common - hypothetical protein Pfl_2290 19 COG4637 COG4637, Predicted ATPase General function prediction only 77459956 Common - DNA polymerase II Pfl_3734 64 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 77457174 Common - Insecticidal toxin protein, putative Pfl_0947 53 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 77460690 Common - Twin-arginine translocation pathway signal Pfl_4469 38 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77456858 Common - Multi antimicrobial extrusion protein MatE Pfl_0630 85 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 77457192 Common - MoaD Pfl_0965 45 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 77460679 Common - Two Component, Sigma-54 Specific, Transcriptional Regulator, Fis family Pfl_4458 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77460366 Common - Protein of unknown function DUF1285 Pfl_4145 45 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 77457143 Common - YebG Pfl_0916 3 COG3141 COG3141, Uncharacterized protein conserved in bacteria Function unknown 77458211 Common - Fimbrial assembly Pfl_1984 8 None None None 77457355 Common truD tRNA pseudouridine synthase D Pfl_1128 84 COG0585 COG0585, Uncharacterized conserved protein Function unknown 77459351 Common - Fatty acid hydroxylase Pfl_3129 12 COG3000 ERG3, Sterol desaturase Lipid metabolism 77456791 Common ureE urease accessory protein UreE Pfl_0563 62 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 77457928 Common - Xanthine/uracil permease Pfl_1701 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 77460096 Common - hypothetical protein Pfl_3875 1 None None None 77460438 Common - (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA Pfl_4217 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 77458699 Common - Transcriptional Regulator, AraC family Pfl_2474 115 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77456835 Common - Precorrin-3B C17-methyltransferase region Pfl_0607 118 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 161485592 Common - bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase Pfl_3395 215 COG1049 AcnB, Aconitase B Energy production and conversion 77458791 Common - hypothetical protein Pfl_2566 1 None None None 77460181 Common - Molybdopterin biosynthesis protein MoeA Pfl_3960 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 77461329 Common - putative ubiquinone biosynthesis protein Pfl_5108 48 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 77461283 Common rpsE 30S ribosomal protein S5 Pfl_5062 246 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 77457604 Common - Protein of unknown function DUF344 Pfl_1377 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 77458261 Common - VanW Pfl_2034 34 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 77461338 Common - Outer membrane autotransporter barrel Pfl_5117 50 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 77458814 Common nhaB sodium/proton antiporter Pfl_2589 25 COG3067 NhaB, Na+/H+ antiporter Inorganic ion transport and metabolism 77460493 Common - hypothetical protein Pfl_4272 1 None None None 77460469 Common flgE flagellar hook protein FlgE Pfl_4248 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 77461001 Common - hypothetical protein Pfl_4780 56 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 77457719 Common - Pseudouridine synthase, Rsu Pfl_1492 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 77459253 Common - hypothetical protein Pfl_3031 3 None None None 77461421 Common - hypothetical protein Pfl_5200 30 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 77461487 Common - glyceraldehyde-3-phosphate dehydrogenase Pfl_5266 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 77458044 Common - hypothetical protein Pfl_1817 21 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 77457188 Common - hypothetical protein Pfl_0961 84 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 77458351 Common - FAD dependent oxidoreductase Pfl_2124 122 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77456337 Common - hypothetical protein Pfl_0109 3 None None None 77456541 Common - GABA permease Pfl_0313 175 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 77459223 Common - DNA topoisomerase III Pfl_3001 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 77461024 Common - hypothetical protein Pfl_4803 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 77458251 Common - UDP-glucose/GDP-mannose dehydrogenase Pfl_2024 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 77461268 Common - hypothetical protein Pfl_5047 1 COG5463 COG5463, Predicted integral membrane protein Function unknown 77457122 Common - hypothetical protein Pfl_0895 2 None None None 77459387 Common - Oxidoreductase-like Pfl_3165 173 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 77456558 Common - Protein of unknown function DUF610 Pfl_0330 64 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 77461164 Common - Acyl-CoA dehydrogenase-like Pfl_4943 135 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77460950 Common - Xanthine/uracil permease Pfl_4729 130 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 77457308 Common - Filamentation induced by cAMP protein Fic Pfl_1081 77 COG3177 COG3177, Uncharacterized conserved protein Function unknown 77458433 Common - OsmC-like protein Pfl_2206 87 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77459285 Nonpathogen - hypothetical protein Pfl_3063 1 None None None 77457656 Common - Alpha/beta hydrolase fold Pfl_1429 180 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77459207 Common - transposase, OrfB Pfl_2982 126 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 77457000 Common - Dihydropteroate synthase Pfl_0773 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 77456494 Common - hypothetical protein Pfl_0266 14 None None None 77457733 Common flgK flagellar hook-associated protein FlgK Pfl_1506 137 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 77457846 Common - Branched-chain amino acid transport system II carrier protein Pfl_1619 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 77459040 Common - Lipopolysaccharide biosynthesis Pfl_2815 148 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 77460862 Common - hypothetical protein Pfl_4641 2 None None None 77456776 Common - nicotinate phosphoribosyltransferase Pfl_0548 60 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 77458748 Common - Acriflavin resistance protein Pfl_2523 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77458532 Common - D-amino-acid dehydrogenase Pfl_2305 110 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77458218 Common - curli assembly protein CsgE Pfl_1991 9 None None None 77458606 Common - General substrate transporter Pfl_2379 132 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77458589 Common - Transcriptional Regulator, LysR family Pfl_2362 177 COG0583 LysR, Transcriptional regulator Transcription 77460727 Common - ParA family protein Pfl_4506 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77461347 Common - Two Component Transcriptional Regulator, LuxR family Pfl_5126 217 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77459865 Common - Secretion protein HlyD Pfl_3643 150 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77458223 Common - Curlin associated Pfl_1996 20 None None None 77457995 Common prpD 2-methylcitrate dehydratase Pfl_1768 59 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 77461646 Common - hypothetical protein Pfl_5425 3 None None None 77458980 Common - transcriptional regulator NfxB Pfl_2755 8 COG3413 COG3413, Predicted DNA binding protein General function prediction only 77461470 Common - Fumarate reductase/succinate dehydrogenase flavoprotein-like Pfl_5249 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 77460612 Common gcvH glycine cleavage system protein H Pfl_4391 184 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 77461736 Common - chemotaxis sensory transducer Pfl_5515 169 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77459742 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_3520 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77457295 Common - hypothetical protein Pfl_1068 6 None None None 77456547 Common - hypothetical protein Pfl_0319 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 77460892 Common ddl D-alanine--D-alanine ligase Pfl_4671 226 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 77461806 Common - Protein of unknown function DUF1305 Pfl_5585 43 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 77461053 Common - hypothetical protein Pfl_4832 3 COG3767 COG3767, Uncharacterized low-complexity protein Function unknown 77457332 Common - Di-trans-poly-cis-decaprenylcistransferase Pfl_1105 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 77456439 Common - sulfate ester transport system substrate-binding protein Pfl_0211 72 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 77456699 Common - hypothetical protein Pfl_0471 7 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 77461641 Common - acetylornithine deacetylase Pfl_5420 194 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 77457367 Common - hypothetical protein Pfl_1140 2 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 161485587 Common - anti-RNA polymerase sigma 70 factor Pfl_5482 24 COG3160 Rsd, Regulator of sigma D Transcription 77460206 Common - thiopurine S-methyltransferase Pfl_3985 32 None None None 77456602 Common - glucosyltransferase MdoH Pfl_0374 54 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 77460640 Common - outer membrane porin Pfl_4419 15 None None None 77460902 Common mraW S-adenosyl-methyltransferase MraW Pfl_4681 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 77460552 Common - GCN5-related N-acetyltransferase Pfl_4331 20 COG0456 RimI, Acetyltransferases General function prediction only 77461086 Common - hypothetical protein Pfl_4865 1 None None None 77456233 Common - Two component Transcriptional regulator, Winged helix family Pfl_0005 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77460006 Common - TonB-dependent siderophore receptor Pfl_3784 125 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 77458268 Nonpathogen - hypothetical protein Pfl_2041 2 None None None 77459592 Common - hypothetical protein Pfl_3370 1 None None None 77460867 Common - cytochrome o ubiquinol oxidase, subunit III Pfl_4646 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 77459975 Common - hypothetical protein Pfl_3753 8 None None None 77456692 Common - Glutamate-ammonia-ligase adenylyltransferase Pfl_0464 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 77460869 Common - Cytochrome o ubiquinol oxidase subunit II Pfl_4648 128 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 77459394 Common - hypothetical protein Pfl_3172 74 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 77461678 Common - Thioredoxin Pfl_5457 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 77460875 Common - CheW protein Pfl_4654 153 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77461475 Common - hypothetical protein Pfl_5254 40 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 77456499 Nonpathogen - hypothetical protein Pfl_0271 1 None None None 77456355 Common - hypothetical protein Pfl_0127 4 None None None 77456407 Common - N-glycosyltransferase PgaC Pfl_0179 215 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77461111 Common - Methyltransferase small Pfl_4890 82 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 77458593 Common - Transcriptional Regulator, XRE family Pfl_2366 8 COG1709 COG1709, Predicted transcriptional regulator Transcription 77460070 Common - Response regulator receiver (CheY) modulated Serine phosphatase Pfl_3849 226 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 77459926 Common - hypothetical protein Pfl_3704 1 None None None 77459687 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 Pfl_3465 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 77459238 Nonpathogen - hypothetical protein Pfl_3016 1 None None None 77459131 Nonpathogen - hypothetical protein Pfl_2906 1 None None None 77458453 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pfl_2226 6 None None None 77456645 Common - Transcriptional Regulator, LysR family Pfl_0417 190 COG0583 LysR, Transcriptional regulator Transcription 77458708 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_2483 113 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77456861 Common - methyltransferase, putative Pfl_0633 90 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 77458974 Common - transporter, putative Pfl_2749 142 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 77457939 Common - Transcriptional Regulator, MarR family Pfl_1712 39 COG1846 MarR, Transcriptional regulators Transcription 77457411 Common - Transcriptional Regulator, LysR family Pfl_1184 192 COG0583 LysR, Transcriptional regulator Transcription 77460573 Common - hypothetical protein Pfl_4352 1 None None None 77461069 Common - general secretion pathway protein H Pfl_4848 19 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 77457595 Common - hypothetical protein Pfl_1368 85 COG0628 PerM, Predicted permease General function prediction only 77458144 Common - L-asparaginase, type II Pfl_1917 131 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 77458473 Common - chaperone protein HchA Pfl_2246 15 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 77460128 Common - Short-chain dehydrogenase/reductase SDR Pfl_3907 216 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77461510 Common - extracellular solute-binding protein, family 3 Pfl_5289 155 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77461184 Common - lipoyl synthase Pfl_4963 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 77458021 Common - guanine deaminase Pfl_1794 154 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 77459521 Common - AzlC-like Pfl_3299 99 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 77457685 Common - Transcriptional Regulator, LysR family Pfl_1458 170 COG0583 LysR, Transcriptional regulator Transcription 77460925 Common - Beta-lactamase-like Pfl_4704 216 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77459347 Common - Putative FecR Pfl_3125 48 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77459435 Common - hypothetical protein Pfl_3213 35 None None None 77456886 Common - Protein of unknown function RIO1 Pfl_0658 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 77458375 Common - Formate dehydrogenase, subunit FdhD Pfl_2148 134 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 77459556 Common - hypothetical protein Pfl_3334 16 COG3673 COG3673, Uncharacterized conserved protein Function unknown 77461636 Common - NAD(P)H-dependent FMN reductase Pfl_5415 56 COG0431 COG0431, Predicted flavoprotein General function prediction only 77461295 Common rplV 50S ribosomal protein L22 Pfl_5074 224 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 77456259 Common - Citrate transporter Pfl_0031 38 COG2851 CitM, H+/citrate symporter Energy production and conversion 77458316 Common - Cytochrome c biogenesis protein, transmembrane region Pfl_2089 128 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 77461032 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase Pfl_4811 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 77456803 Common - hypothetical protein Pfl_0575 17 COG0628 PerM, Predicted permease General function prediction only 77458874 Common - Response Regulator Receiver Signal Transduction Histidine Kinase Pfl_2649 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456551 Common hisB imidazoleglycerol-phosphate dehydratase Pfl_0323 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 77459149 Common - Pyridine nucleotide-disulphide oxidoreductase, class-II, active site Pfl_2924 248 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 77461361 Common - hypothetical protein Pfl_5140 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 77456507 Common - Oxidoreductase alpha (molybdopterin) subunit Pfl_0279 173 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 77457571 Nonpathogen - hypothetical protein Pfl_1344 1 None None None 77460882 Common - Secretion protein HlyD Pfl_4661 168 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77460079 Common - Lipoprotein releasing system, ATP-binding protein Pfl_3858 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 77458985 Common - Transcriptional Regulator, AraC family Pfl_2760 77 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77459647 Common - Twin-arginine translocation pathway signal Pfl_3425 115 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 77461695 Common - putative lipoprotein Pfl_5474 29 COG3417 FlgN, Collagen-binding surface adhesin SpaP (antigen I/II family) General function prediction only 77457373 Common - hypothetical protein Pfl_1146 5 COG3498 COG3498, Phage tail tube protein FII General function prediction only 77456753 Common - HflK Pfl_0525 217 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 77456781 Common - inner-membrane translocator Pfl_0553 166 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 77459804 Common - seryl-tRNA synthetase Pfl_3582 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 77461820 Nonpathogen - hypothetical protein Pfl_5599 1 None None None 77460598 Common - Sigma-24 (FecI) Pfl_4377 81 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77461690 Common - Protein of unknown function DUF188 Pfl_5469 96 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 77459212 Common - Transcriptional Regulator, AraC family Pfl_2990 132 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77461568 Common - Glucose-methanol-choline oxidoreductase Pfl_5347 56 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 77459727 Nonpathogen - hypothetical protein Pfl_3505 1 None None None 77459993 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_3771 187 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77460860 Common - Membrane bound O-acyl transferase, MBOAT Pfl_4639 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 77457484 Common - Aromatic amino acid beta-eliminating lyase/threonine aldolase Pfl_1257 230 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 77456287 Common - Periplasmic solute binding protein Pfl_0059 157 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 77457917 Common - putative aminopeptidase 2 Pfl_1690 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 77458394 Common - hypothetical protein Pfl_2167 1 None None None 77460664 Common - ATPase associated with various cellular activities, AAA_3 Pfl_4443 177 COG0714 COG0714, MoxR-like ATPases General function prediction only 77457215 Common - DNA polymerase III subunit chi Pfl_0988 43 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 77458866 Common - Transcriptional Regulator, AraC family Pfl_2641 149 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77457031 Common - Binding-protein-dependent transport systems inner membrane component Pfl_0804 161 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 77457650 Common - Predicted transmembrane transcriptional regulator (anti-Sigma-factor) Pfl_1423 4 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 77458688 Nonpathogen - hypothetical protein Pfl_2463 1 None None None 77459685 Common - Dehydrogenase, E1 component Pfl_3463 153 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 77456802 Common - PsiF Pfl_0574 22 None None None 77460395 Common - Protein of unknown function DUF343 Pfl_4174 104 COG2835 COG2835, Uncharacterized conserved protein Function unknown 77458003 Common - RNA polymerase sigma factor SigX Pfl_1776 141 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77456318 Common - Peptidase M3A and M3B, thimet/oligopeptidase F Pfl_0090 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 77461305 Common rpsL 30S ribosomal protein S12 Pfl_5084 237 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 77456347 Common - hypothetical protein Pfl_0119 1 None None None 77459607 Common - Cytochrome bd ubiquinol oxidase, subunit II Pfl_3385 154 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 77461370 Common - RNA polymerase sigma factor RpoD Pfl_5149 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 77458997 Common - hypothetical protein Pfl_2772 97 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 77459202 Common - Aldehyde dehydrogenase Pfl_2977 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77456714 Common - Aldo/keto reductase Pfl_0486 191 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 77457176 Common - Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Pfl_0949 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 77459891 Common - Fimbrial biogenesis outer membrane usher protein Pfl_3669 40 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 77456815 Common - ABC transporter-like Pfl_0587 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 77458106 Common - Transcriptional Regulator, TetR family Pfl_1879 55 COG1309 AcrR, Transcriptional regulator Transcription 77458120 Common - aspartate-semialdehyde dehydrogenase Pfl_1893 200 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 77457565 Common - Allophanate hydrolase subunit 2 Pfl_1338 233 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 77457416 Common - RNA-binding S4 Pfl_1189 87 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 77458007 Common - Rieske (2Fe-2S) region Pfl_1780 85 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 77458899 Common - Transcriptional Regulator, AraC family Pfl_2674 49 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77458393 Common - 3-demethylubiquinone-9 3-methyltransferase Pfl_2166 65 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 77457639 Common - hypothetical protein Pfl_1412 8 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 77459274 Common - 37kDa nucleoid-associated protein Pfl_3052 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 77461829 Common - hypothetical protein Pfl_5608 216 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 77458990 Common - Integrase, catalytic region Pfl_2765 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 77457227 Common - hypothetical protein Pfl_1000 53 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 77461517 Common - acyl-carrier-protein S-malonyltransferase Pfl_5296 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 77460820 Common - hypothetical protein Pfl_4599 61 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 77456737 Common psd phosphatidylserine decarboxylase Pfl_0509 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 77456565 Common - RNA methyltransferase TrmH, group 2 Pfl_0337 158 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 77458112 Common - Heat shock protein DnaJ-like Pfl_1885 6 COG3152 COG3152, Predicted membrane protein Function unknown 77456311 Common - Radical SAM Pfl_0083 105 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 77457665 Common - hypothetical protein Pfl_1438 2 None None None 77456372 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_0144 121 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77461723 Common - HAD-superfamily hydrolase subfamily IA, variant 1 and 3 Pfl_5502 141 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 77459185 Common - Benzoate membrane transport protein Pfl_2960 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 77461137 Common - Palmitoyl-CoA hydrolase Pfl_4916 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 77461625 Common - extracellular solute-binding protein, family 1 Pfl_5404 132 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77460259 Common - 3-oxoacyl-(acyl carrier protein) synthase Pfl_4038 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77460712 Common - Protein of unknown function DUF1513 Pfl_4491 24 COG3490 COG3490, Uncharacterized protein conserved in bacteria Function unknown 77457321 Common - hypothetical protein Pfl_1094 106 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 77461706 Common - Protein of unknown function DUF513 Pfl_5485 37 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 77456844 Common - hypothetical protein Pfl_0616 17 None None None 77457084 Common - RNA polymerase factor sigma-54 Pfl_0857 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 77459900 Common - Rhs element Vgr protein Pfl_3678 47 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 77459916 Common - Histone-like DNA-binding protein Pfl_3694 174 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 77457067 Common - Rod shape-determining protein MreD Pfl_0840 51 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 77460235 Common - Lipolytic enzyme, G-D-S-L Pfl_4014 104 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 77459770 Common - hypothetical protein Pfl_3548 4 None None None 77461358 Common apaH diadenosine tetraphosphatase Pfl_5137 94 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 77459426 Common - Cupin region Pfl_3204 24 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 77457795 Common motC flagellar motor protein Pfl_1568 123 COG1291 MotA, Flagellar motor component Cell motility and secretion 77457875 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Pfl_1648 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 77460056 Common - UDP-glucose 4-epimerase Pfl_3834 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 77457509 Common - NADH:flavin oxidoreductase/NADH oxidase Pfl_1282 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77456965 Common - hypothetical protein Pfl_0738 14 None None None 77457850 Common - Phenylacetic acid degradation-like protein Pfl_1623 25 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 77461662 Common - Secretion protein HlyD Pfl_5441 138 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77458184 Common - Transcriptional Regulator, Winged helix family Pfl_1957 65 COG3903 COG3903, Predicted ATPase General function prediction only 77459002 Nonpathogen - hypothetical protein Pfl_2777 1 None None None 77458892 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_2667 188 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77457045 Common - Protein of unknown function DUF541 Pfl_0818 33 COG3471 COG3471, Predicted periplasmic/secreted protein Function unknown 77458039 Common - hypothetical protein Pfl_1812 4 None None None 77458678 Common - Transcriptional Regulator, AraC family Pfl_2453 142 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77457710 Common - Two component Transcriptional regulator, Winged helix family Pfl_1483 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77459071 Common - hypothetical protein Pfl_2846 5 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 77457433 Common - ABC transporter-like Pfl_1206 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 77459309 Common - Transcriptional Regulator, IclR family Pfl_3087 84 COG1414 IclR, Transcriptional regulator Transcription 77456788 Common - HupE/UreJ protein Pfl_0560 23 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 77457697 Common - LysM domain protein Pfl_1470 31 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 77457384 Common - TMP Pfl_1157 27 None None None 77460732 Common - Electron transport complex, RnfABCDGE type, G subunit Pfl_4511 58 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 77456297 Common - ISPsy11, transposase OrfA Pfl_0069 9 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 77460715 Common - hypothetical protein Pfl_4494 1 None None None 77460284 Common - GCN5-related N-acetyltransferase Pfl_4063 47 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 77461916 Common - AAA ATPase, central region Pfl_5696 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 77459769 Nonpathogen - hypothetical protein Pfl_3547 1 None None None 77457630 Common - Transcriptional Regulator, LysR family Pfl_1403 190 COG0583 LysR, Transcriptional regulator Transcription 77456739 Common - Predicted signal transduction protein Pfl_0511 2 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 77458886 Common - hypothetical protein Pfl_2661 23 COG4268 McrC, McrBC 5-methylcytosine restriction system component Defense mechanisms 77456255 Common - Transcriptional Regulator, LysR family Pfl_0027 158 COG0583 LysR, Transcriptional regulator Transcription 77457621 Common - hypothetical protein Pfl_1394 1 COG5637 COG5637, Predicted integral membrane protein Function unknown 77461933 Nonpathogen - hypothetical protein Pfl_5715 1 None None None 77456467 Common - Acyl-CoA dehydrogenase-like Pfl_0239 140 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77459244 Common - hypothetical protein Pfl_3022 21 None None None 77459656 Common - amidohydrolase Pfl_3434 165 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 77461170 Common - hypothetical protein Pfl_4949 15 COG4517 COG4517, Uncharacterized protein conserved in bacteria Function unknown 77459133 Common - Glycerate kinase Pfl_2908 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 77461777 Common - biopolymer transport protein ExbD Pfl_5556 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 77460584 Common - glucose-6-phosphate 1-dehydrogenase Pfl_4363 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 77459857 Common - ABC transporter-like Pfl_3635 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 77460937 Common - Protein of unknown function DUF159 Pfl_4716 100 COG2135 COG2135, Uncharacterized conserved protein Function unknown 77456395 Common - Protein of unknown function DUF107 Pfl_0167 40 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 77457709 Common - hypothetical protein Pfl_1482 1 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 77460838 Common - hypothetical protein Pfl_4617 17 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 77457281 Common - MCP methyltransferase, CheR-type Pfl_1054 150 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 77459321 Common - Cobalamin synthesis protein/P47K Pfl_3099 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 77457092 Common - hypothetical protein Pfl_0865 99 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 77458545 Common - TonB-dependent receptor Pfl_2318 74 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77461130 Common - Xylose isomerase-like TIM barrel Pfl_4909 33 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 77458732 Common - HvnC; halovibrin Pfl_2507 5 None None None 77461628 Common - Glutamine synthetase, catalytic region Pfl_5407 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 77461832 Common - Phosphate uptake regulator, PhoU Pfl_5611 195 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 77457975 Nonpathogen - Rickettsia 17 kDa surface antigen Pfl_1748 1 COG5038 COG5038, Ca2+-dependent lipid-binding protein, contains C2 domain General function prediction only 77457454 Common - Beta-lactamase Pfl_1227 79 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 77461054 Common - chemotaxis sensory transducer Pfl_4833 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77459089 Common - Enoyl-CoA hydratase/isomerase Pfl_2864 172 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77460855 Common - Prevent-host-death protein Pfl_4634 52 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 77459639 Common - hypothetical protein Pfl_3417 6 None None None 77459166 Common - Molybdenum ABC transporter, periplasmic binding protein Pfl_2941 135 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 77460358 Common - ADP-ribosylation/Crystallin J1 Pfl_4137 63 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 77456656 Common - FAD dependent oxidoreductase Pfl_0428 50 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 77456951 Common - Amidohydrolase Pfl_0723 73 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 77460625 Common - Biopolymer transport protein ExbD/TolR Pfl_4404 130 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 77456598 Common - Lipolytic enzyme Pfl_0370 122 COG0657 Aes, Esterase/lipase Lipid metabolism 77457288 Common - Possible Transcriptional Regulator, TetR family Pfl_1061 7 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 77459036 Common - TspO and MBR like proteins Pfl_2811 56 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 77459330 Common - Leucine-rich repeat Pfl_3108 4 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 77459621 Common - 4-oxalocrotonate tautomerase Pfl_3399 33 None None None 77457869 Common - cobyrinic acid a,c-diamide synthase Pfl_1642 137 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 77458032 Common - DNA polymerase III subunits gamma and tau Pfl_1805 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 77457151 Common - Putative FecR Pfl_0924 44 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77456261 Common - Transposase, IS4 Pfl_0033 49 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 77459356 Common - Anti-Sigma-factor antagonist (STAS) Pfl_3134 30 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 77459630 Common - Protein of unknown function DUF796 Pfl_3408 22 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 77461688 Common - hypothetical protein Pfl_5467 75 COG3000 ERG3, Sterol desaturase Lipid metabolism 77458614 Nonpathogen - hypothetical protein Pfl_2387 1 None None None 77460163 Common - hypothetical protein Pfl_3942 44 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 77456303 Common - hypothetical protein Pfl_0075 4 None None None 77459907 Common - Cytochrome B561 Pfl_3685 85 COG3038 CybB, Cytochrome B561 Energy production and conversion 77461882 Common - transferase hexapeptide repeat Pfl_5662 185 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 77457446 Common - hypothetical protein Pfl_1219 8 None None None 77459663 Common - dihydropyrimidinase Pfl_3441 198 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 77459738 Common - Ferredoxin Pfl_3516 30 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 77456423 Common - Sulfate ABC transporter, permease protein CysT Pfl_0195 236 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 77460194 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein Pfl_3973 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 77461388 Common - Acyl-CoA dehydrogenase-like Pfl_5167 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77459710 Nonpathogen - hypothetical protein Pfl_3488 1 None None None 77461340 Common gph phosphoglycolate phosphatase Pfl_5119 203 COG0546 Gph, Predicted phosphatases General function prediction only 77461552 Common - sulfur carrier protein ThiS Pfl_5331 74 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 77458201 Common - Lytic transglycosylase, catalytic Pfl_1974 177 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 77460708 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Pfl_4487 173 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77457097 Common hisG ATP phosphoribosyltransferase catalytic subunit Pfl_0870 210 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 77457741 Common - DegT/DnrJ/EryC1/StrS aminotransferase Pfl_1514 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 77460754 Common - Transcriptional Regulator, DeoR family Pfl_4533 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 77456640 Common - hypothetical protein Pfl_0412 45 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 77458010 Common - Nitrate transporter Pfl_1783 109 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 77457893 Common - Small multidrug resistance protein Pfl_1666 130 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 77457785 Nonpathogen - hypothetical protein Pfl_1558 1 None None None 77461906 Common - Glycosyl transferase, group 1 Pfl_5686 112 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77460942 Common - hypothetical protein Pfl_4721 1 None None None 77461746 Common - Endoribonuclease L-PSP Pfl_5525 149 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77457859 Common purN phosphoribosylglycinamide formyltransferase Pfl_1632 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 77456379 Common - lipoprotein, putative Pfl_0151 1 None None None 77459080 Common - extracellular solute-binding protein, family 3 Pfl_2855 168 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77457461 Common - Na+/H+ antiporter NhaA Pfl_1234 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 77460254 Common - potassium-transporting ATPase subunit A Pfl_4033 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 77460672 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_4451 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77458942 Common - Transcriptional Regulator, AraC family Pfl_2717 149 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77459067 Common - Glycosyl transferase, family 2 Pfl_2842 211 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77458671 Common - Twin-arginine translocation pathway signal Pfl_2446 98 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 77461366 Common - hypothetical protein Pfl_5145 148 COG0344 COG0344, Predicted membrane protein Function unknown 77459777 Common - Transcriptional Regulator, AraC family Pfl_3555 122 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77457328 Common rpsB 30S ribosomal protein S2 Pfl_1101 227 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 77460178 Common - Two Component Transcriptional Regulator, LuxR family Pfl_3957 217 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77457020 Common - Phosphoenolpyruvate-protein phosphotransferase Pfl_0793 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 77460779 Common - Transcriptional Regulator, LuxR family Pfl_4558 69 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77459514 Common - Polysaccharide deacetylase Pfl_3292 19 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 77460908 Common - Transport-associated Pfl_4687 69 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 77458654 Common - hypothetical protein Pfl_2429 12 None None None 77460808 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Pfl_4587 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 77456768 Common - hypothetical protein Pfl_0540 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 77460887 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_4666 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77458217 Common - hypothetical protein Pfl_1990 11 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77457774 Common fliN flagellar motor switch protein Pfl_1547 122 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 77457947 Common - hypothetical protein Pfl_1720 3 None None None 77459268 Common - hypothetical protein Pfl_3046 1 None None None 77457790 Common fliA flagellar biosynthesis sigma factor Pfl_1563 215 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 77459594 Common - Glutamate-5-semialdehyde dehydrogenase Pfl_3372 180 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 77460105 Common - ABC transporter, ATP-binding/permease protein Pfl_3884 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 77457940 Common - Aminotransferase, class I and II Pfl_1713 221 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 77458821 Common - hypothetical protein Pfl_2596 1 None None None 77460989 Common - Short chain fatty acid transporter Pfl_4768 40 COG2031 AtoE, Short chain fatty acids transporter Lipid metabolism 77458675 Common - Transcriptional Regulator, LysR family Pfl_2450 126 COG0583 LysR, Transcriptional regulator Transcription 77461143 Common - Transcriptional Regulator, AsnC family Pfl_4922 152 COG1522 Lrp, Transcriptional regulators Transcription 77457466 Common - Transcriptional Regulator, LysR family Pfl_1239 108 COG0583 LysR, Transcriptional regulator Transcription 77459102 Common - Transcriptional Regulator, TetR family Pfl_2877 85 COG1309 AcrR, Transcriptional regulator Transcription 77460482 Common - Response regulator receiver domain protein (CheY) Pfl_4261 62 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77460880 Common - hypothetical protein Pfl_4659 1 None None None 77461500 Common - Thioesterase superfamily Pfl_5279 49 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 77461692 Common - hypothetical protein Pfl_5471 26 COG3014 COG3014, Uncharacterized protein conserved in bacteria Function unknown 77458587 Common - isopropylmalate isomerase large subunit Pfl_2360 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 77459887 Common - Catalase-like Pfl_3665 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 77460683 Common - hypothetical protein Pfl_4462 89 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 77458910 Common - Triacylglycerol lipase Pfl_2685 61 None None None 77458171 Common - Regulator of RNA terminal phosphate cyclase Pfl_1944 162 COG4650 RtcR, Sigma54-dependent transcription regulator containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 77460331 Common - hypothetical protein Pfl_4110 37 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 77456351 Common - Sigma-24 (FecI) Pfl_0123 95 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77459109 Common - hypothetical protein Pfl_2884 21 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 77456628 Common - primosome assembly protein PriA Pfl_0400 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 77461650 Common - Binding-protein-dependent transport systems inner membrane component Pfl_5429 152 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 77459405 Nonpathogen - hypothetical protein Pfl_3183 1 None None None 77458336 Common - putative xanthine dehydrogenase iron-sulfur-binding subunit Pfl_2109 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 77459611 Common - hypothetical protein Pfl_3389 56 COG3781 COG3781, Predicted membrane protein Function unknown 77458149 Common - Transcriptional Regulator, LacI family Pfl_1922 129 COG1609 PurR, Transcriptional regulators Transcription 77459043 Common - Glycosyl transferase WecB/TagA/CpsF Pfl_2818 45 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 77461450 Common - Transcriptional Regulator, AraC family Pfl_5229 138 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77461049 Common - hypothetical protein Pfl_4828 1 None None None 77458232 Nonpathogen - hypothetical protein Pfl_2005 1 None None None 77458103 Common - Drug resistance transporter EmrB/QacA subfamily Pfl_1876 179 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77458566 Common - inner-membrane translocator Pfl_2339 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 77459561 Nonpathogen - universal stress protein family Pfl_3339 1 None None None 77456881 Common - hypothetical protein Pfl_0653 6 None None None 77458795 Common - Transcriptional Regulator, LysR family Pfl_2570 118 COG0583 LysR, Transcriptional regulator Transcription 77459793 Common - GCN5-related N-acetyltransferase Pfl_3571 33 COG0456 RimI, Acetyltransferases General function prediction only 77461376 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pfl_5155 210 COG0388 COG0388, Predicted amidohydrolase General function prediction only 77459511 Common - hypothetical protein Pfl_3289 1 None None None 77457569 Common - Binding-protein-dependent transport systems inner membrane component Pfl_1342 118 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 77456659 Common - Outer membrane lipoprotein carrier protein LolA Pfl_0431 28 None None None 77457319 Common - Aromatic amino acid beta-eliminating lyase/threonine aldolase Pfl_1092 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 77461871 Common - hypothetical protein Pfl_5651 11 None None None 77459549 Common - Transcriptional regulators, TraR/DksA family Pfl_3327 137 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 77456740 Common - flagellar motor protein MotA Pfl_0512 118 COG1291 MotA, Flagellar motor component Cell motility and secretion 77457473 Common livM leucine/isoleucine/valine transporter permease subunit Pfl_1246 152 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 77456575 Common - GTP-binding protein TypA Pfl_0347 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 77460210 Common - hypothetical protein Pfl_3989 30 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 77457013 Common - Protein of unknown function DUF1631) Pfl_0786 21 None None None 77459358 Common - Anti-Sigma-regulatory factor (Ser/Thr protein kinase and phosphatase) Pfl_3136 31 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 77458338 Nonpathogen - hypothetical protein Pfl_2111 1 None None None 77461114 Common - Cytochrome bd ubiquinol oxidase, subunit I Pfl_4893 165 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 77458208 Common - Response regulator receiver domain protein (CheY) Pfl_1981 221 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 77461813 Common - PAAR Pfl_5592 32 COG4104 COG4104, Uncharacterized conserved protein Function unknown 77460323 Common - Peptidase M42 Pfl_4102 59 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 77456958 Common - PAP2 superfamily protein Pfl_0730 23 COG3907 COG3907, PAP2 (acid phosphatase) superfamily protein General function prediction only 77459213 Nonpathogen - hypothetical protein Pfl_2991 1 None None None 77460095 Common - hypothetical protein Pfl_3874 4 None None None 77460579 Common - hypothetical protein Pfl_4358 42 COG3530 COG3530, Uncharacterized protein conserved in bacteria Function unknown 77458504 Common - hypothetical protein Pfl_2277 3 None None None 77456519 Common - Porphyromonas-type peptidyl-arginine deiminase Pfl_0291 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 77457580 Common - hypothetical protein Pfl_1353 65 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 77460658 Common - transcriptional regulator, putative Pfl_4437 4 None None None 77456285 Common - hypothetical protein Pfl_0057 11 None None None 77461767 Common - hypothetical protein Pfl_5546 19 COG3296 COG3296, Uncharacterized protein conserved in bacteria Function unknown 77460044 Common - hypothetical protein Pfl_3822 3 None None None 77459716 Nonpathogen - hypothetical protein Pfl_3494 1 None None None 77456456 Common - extracellular solute-binding protein, family 3 Pfl_0228 159 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77460411 Common - hypothetical protein Pfl_4190 52 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 77458066 Common - Glycoside hydrolase 15-like Pfl_1839 69 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 77456771 Common - Transglutaminase-like Pfl_0543 104 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 77460418 Common - Two component Transcriptional regulator, Winged helix family Pfl_4197 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77456363 Common - ABC transporter-like Pfl_0135 232 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 77456486 Common - Phenylacetic acid degradation-like protein Pfl_0258 86 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 77458328 Common - hypothetical protein Pfl_2101 6 None None None 77456323 Common - lipoprotein, putative Pfl_0095 1 None None None 77458854 Common - hypothetical protein Pfl_2629 6 None None None 77461727 Common - Nitrogen regulatory protein P-II (GlnB, GlnK) Pfl_5506 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 77459558 Common - Antibiotic biosynthesis monooxygenase Pfl_3336 25 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 77461947 Common - F0F1 ATP synthase subunit beta Pfl_5730 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 77460397 Common - Biopolymer transport protein ExbD/TolR Pfl_4176 30 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 77460896 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase Pfl_4675 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 77461464 Common - betaine aldehyde dehydrogenase Pfl_5243 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77459735 Common - Potassium efflux system protein Pfl_3513 193 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 77460561 Common - General substrate transporter Pfl_4340 129 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77457043 Common - extracellular solute-binding protein, family 5 Pfl_0816 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 77457745 Common - NAD-dependent epimerase/dehydratase Pfl_1518 178 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77460676 Common - Insecticidal toxin protein, putative Pfl_4455 53 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 77457865 Common - NLP/P60 Pfl_1638 140 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 77458049 Common - Cytochrome C oxidase, mono-heme subunit/FixO Pfl_1822 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 77461190 Common - Rod shape-determining protein RodA Pfl_4969 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 77460510 Common - Succinylglutamate desuccinylase/aspartoacylase Pfl_4289 23 COG3608 COG3608, Predicted deacylase General function prediction only 77461334 Common trpC indole-3-glycerol-phosphate synthase Pfl_5113 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 77456513 Common - 3(2),5 -bisphosphate nucleotidase Pfl_0285 181 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 77457405 Nonpathogen - hypothetical protein Pfl_1178 1 None None None 77459312 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_3090 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77457541 Common - L-carnitine dehydratase/bile acid-inducible protein F Pfl_1314 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 77459128 Common - General substrate transporter Pfl_2903 145 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77457888 Common - Transcriptional Regulator, TetR family Pfl_1661 23 COG1309 AcrR, Transcriptional regulator Transcription 77458756 Common - hypothetical protein Pfl_2531 1 None None None 77457178 Common - alginate biosynthesis protein AlgJ Pfl_0951 8 None None None 77459966 Common - ABC transporter-like Pfl_3744 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 77456919 Common - hypothetical protein Pfl_0691 17 None None None 77460111 Common acnA aconitate hydratase Pfl_3890 222 COG1048 AcnA, Aconitase A Energy production and conversion 77461234 Common - Phosphatidylglycerophosphatase A Pfl_5013 105 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 77460728 Common metG methionyl-tRNA synthetase Pfl_4507 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77459696 Common - Protein of unknown function DUF156 Pfl_3474 58 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 77461134 Common - Protein of unknown function Zinc binding 2 Pfl_4913 86 COG2321 COG2321, Predicted metalloprotease General function prediction only 77456980 Common - L-lactate permease Pfl_0753 104 COG1620 LldP, L-lactate permease Energy production and conversion 77461441 Common - Electron transfer flavoprotein beta-subunit Pfl_5220 13 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 77461958 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Pfl_5741 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 77458961 Common - Endoribonuclease L-PSP Pfl_2736 163 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77456727 Common - DNA topoisomerase IV subunit B Pfl_0499 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 77461507 Common - Amine oxidase Pfl_5286 57 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 77459227 Common - DNA repair protein RadC Pfl_3005 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 77458633 Common - NmrA-like Pfl_2406 10 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 77458465 Common - Short-chain dehydrogenase/reductase SDR Pfl_2238 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77458405 Common - ABC transporter-like Pfl_2178 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 77461721 Common - Protein of unknown function DUF484 Pfl_5500 56 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 77456464 Common - ABC transporter-like Pfl_0236 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 77461393 Common bioD dithiobiotin synthetase Pfl_5172 149 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 77458321 Common - Protein of unknown function DUF533 Pfl_2094 11 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 77457537 Common - hypothetical protein Pfl_1310 16 None None None 77459078 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_2853 176 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77457225 Common - Lytic transglycosylase, catalytic Pfl_0998 142 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 77460340 Common - Transcriptional Regulator, AraC family Pfl_4119 127 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77456637 Common - type II and III secretion system protein Pfl_0409 143 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 77458196 Common - Esterase/lipase/thioesterase Pfl_1969 130 COG0657 Aes, Esterase/lipase Lipid metabolism 77458421 Common - hypothetical protein Pfl_2194 19 COG3782 COG3782, Uncharacterized protein conserved in bacteria Function unknown 77459698 Nonpathogen - hypothetical protein Pfl_3476 1 None None None 77456670 Common - Cobyrinic acid a,c-diamide synthase Pfl_0442 215 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77458382 Common - putative spermidine/putrescine transport system substrate-binding protein Pfl_2155 127 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77461257 Common - Aminoacyl-tRNA hydrolase Pfl_5036 64 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 77457058 Common - Auxin Efflux Carrier Pfl_0831 140 COG0679 COG0679, Predicted permeases General function prediction only 77460721 Common - Phosphoesterase, PA-phosphatase-like Pfl_4500 24 COG3907 COG3907, PAP2 (acid phosphatase) superfamily protein General function prediction only 77458763 Common - Endonuclease/exonuclease/phosphatase Pfl_2538 64 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 77457555 Common - probable methyl transferase Pfl_1328 121 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77461225 Common - Filamentation induced by cAMP protein Fic Pfl_5004 104 COG3177 COG3177, Uncharacterized conserved protein Function unknown 77460168 Common - Carboxyl transferase Pfl_3947 159 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 77461660 Common - hypothetical protein Pfl_5439 1 None None None 77461896 Common - hypothetical protein Pfl_5676 17 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77458963 Common - Amine oxidase Pfl_2738 52 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 77458449 Common - hypothetical protein Pfl_2222 26 COG5528 COG5528, Predicted integral membrane protein Function unknown 77458846 Common - hypothetical protein Pfl_2621 1 None None None 77457755 Common - Flagellar protein FlaG protein Pfl_1528 30 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 77461279 Common rpsM 30S ribosomal protein S13 Pfl_5058 247 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 77460811 Common - Protein of unknown function DUF81 Pfl_4590 16 COG0730 COG0730, Predicted permeases General function prediction only 77457197 Common - Ornithine cyclodeaminase/mu-crystallin Pfl_0970 61 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 77461179 Common - Rare lipoprotein B Pfl_4958 12 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 77459158 Common - hypothetical protein Pfl_2933 1 None None None 77459307 Common - PfkB Pfl_3085 152 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 77459983 Common - Transcriptional Regulator, AraC family Pfl_3761 75 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77460298 Common - phosphoserine aminotransferase Pfl_4077 114 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 77456678 Common - chemotaxis sensory transducer Pfl_0450 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77457921 Common - Septum site-determining protein MinD Pfl_1694 137 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 77460135 Common - lipoprotein, putative Pfl_3914 1 None None None 77458304 Common - Transcriptional Regulator, LysR family Pfl_2077 192 COG0583 LysR, Transcriptional regulator Transcription 77459365 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3143 206 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 77457108 Common - hypothetical protein Pfl_0881 14 None None None 77456934 Common - Secretion protein HlyD Pfl_0706 173 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77461008 Common ilvH acetolactate synthase 3 regulatory subunit Pfl_4787 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 77458847 Nonpathogen - hypothetical protein Pfl_2622 3 None None None 77456642 Common gltD glutamate synthase subunit beta Pfl_0414 185 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 77460305 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_4084 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77459566 Common - UspA Pfl_3344 34 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 77461261 Common - hypothetical protein Pfl_5040 6 None None None 77461845 Common - Transcriptional Regulator, LysR family Pfl_5624 173 COG0583 LysR, Transcriptional regulator Transcription 77458730 Common - Transcriptional Regulator, LysR family Pfl_2505 3 COG0583 LysR, Transcriptional regulator Transcription 77460253 Common - Potassium-translocating P-type ATPase, B subunit Pfl_4032 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 77458647 Common - Glutathione S-transferase-like Pfl_2422 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77460185 Common - Pseudouridine synthase Pfl_3964 213 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 77461254 Common - MscS Mechanosensitive ion channel Pfl_5033 124 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77459139 Common - Transcriptional Regulator, LysR family Pfl_2914 139 COG0583 LysR, Transcriptional regulator Transcription 77459780 Common - hypothetical protein Pfl_3558 1 None None None 77456999 Common - Peptidase M41, FtsH Pfl_0772 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 77460645 Common - Cobalamin adenosyltransferase Pfl_4424 129 COG2096 COG2096, Uncharacterized conserved protein Function unknown 77461795 Common - Rhs element Vgr protein Pfl_5574 58 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 77456944 Common - Protein of unknown function DUF81 Pfl_0716 28 None None None 77456492 Common - Putative diguanylate phosphodiesterase (EAL domain) Pfl_0264 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77456384 Common - hypothetical protein Pfl_0156 23 COG5305 COG5305, Predicted membrane protein Function unknown 77460999 Common - hypothetical protein Pfl_4778 6 None None None 77458130 Common - O-succinylhomoserine sulfhydrylase Pfl_1903 208 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 77459971 Common - Protein of unknown function DUF1615 Pfl_3749 18 None None None 77458807 Nonpathogen - hypothetical protein Pfl_2582 1 None None None 77460377 Common acpP acyl carrier protein Pfl_4156 182 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77457255 Common - threonine synthase Pfl_1028 135 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 77461245 Common - hypothetical protein Pfl_5024 1 None None None 77458363 Common - hypothetical protein Pfl_2136 2 None None None 77461878 Common - Protein of unknown function DUF198 Pfl_5658 67 COG1469 COG1469, Uncharacterized conserved protein Function unknown 77456458 Common - Secretion protein HlyD Pfl_0230 136 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77458313 Common - Two component Transcriptional regulator, Winged helix family Pfl_2086 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77456926 Common - transferase hexapeptide repeat Pfl_0698 3 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 77457253 Common - Glutaredoxin Pfl_1026 68 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 77459946 Nonpathogen - hypothetical protein Pfl_3724 1 None None None 77457974 Nonpathogen - Rickettsia 17 kDa surface antigen Pfl_1747 1 None None None 77458057 Common - hypothetical protein Pfl_1830 16 COG1106 COG1106, Predicted ATPases General function prediction only 77458172 Common - TROVE Pfl_1945 18 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 77456476 Nonpathogen - hypothetical protein Pfl_0248 1 None None None 77456276 Common - EAL Pfl_0048 161 COG4943 COG4943, Predicted signal transduction protein containing sensor and EAL domains Signal transduction mechanisms 77456356 Common - hypothetical protein Pfl_0128 9 None None None 77458777 Common - hypothetical protein Pfl_2552 88 COG1238 COG1238, Predicted membrane protein Function unknown 77460541 Common - Transcriptional Regulator, LysR family Pfl_4320 143 COG0583 LysR, Transcriptional regulator Transcription 77461197 Common - Phosphoesterase, PA-phosphatase-like Pfl_4976 66 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 77460222 Common - hypothetical protein Pfl_4001 1 None None None 77457806 Common - Cytochrome c-type biogenesis protein CcmC Pfl_1579 123 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 77458412 Common - hypothetical protein Pfl_2185 59 None None None 77461028 Common - Multi-sensor Signal Transduction Histidine Kinase Pfl_4807 224 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 77460918 Common - Transcriptional Regulator, AraC family Pfl_4697 144 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77458347 Common - Spermidine/putrescine ABC transporter ATP-binding subunit Pfl_2120 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77457642 Common - hypothetical protein Pfl_1415 3 None None None 77458597 Common - Porphyromonas-type peptidyl-arginine deiminase Pfl_2370 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 77460003 Common - Diaminopimelate epimerase-like Pfl_3781 16 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 77459828 Common - NADH dehydrogenase subunit E Pfl_3606 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 77459446 Common - Aldehyde dehydrogenase Pfl_3224 177 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77456523 Common - outer membrane porin Pfl_0295 8 None None None 77460479 Common - Major facilitator superfamily MFS_1 Pfl_4258 85 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461226 Common - exodeoxyribonuclease VII small subunit Pfl_5005 130 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 77456290 Common - ABC-3 Pfl_0062 159 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 77458550 Common - benzoate 1,2-dioxygenase ferredoxin reductase subunit Pfl_2323 138 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 77460029 Common - Ribonuclease T2 Pfl_3807 42 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 77457627 Common - hypothetical protein Pfl_1400 1 None None None 77458271 Common - Rhs element Vgr protein Pfl_2044 57 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 77458739 Common - hypothetical protein Pfl_2514 54 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 77457062 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Pfl_0835 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 77457997 Common - phosphoenolpyruvate synthase Pfl_1770 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 77459170 Common - ABC transporter-like Pfl_2945 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 77459283 Common - Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Pfl_3061 10 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 77460370 Common - TatD-like deoxyribonuclease Pfl_4149 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 77458355 Common - hypothetical protein Pfl_2128 2 None None None 77458657 Common - Phosphonate uptake transporter Pfl_2432 86 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 77456510 Common - hypothetical protein Pfl_0282 36 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 77457233 Common - N-acetylglucosamine-6-phosphate deacetylase Pfl_1006 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 77461915 Common - hypothetical protein Pfl_5695 3 None None None 77456618 Common - Poly granule associated Pfl_0390 16 COG5373 COG5373, Predicted membrane protein Function unknown 77460568 Common - Fatty acid desaturase Pfl_4347 12 COG3239 DesA, Fatty acid desaturase Lipid metabolism 77460314 Common - fumarate hydratase Pfl_4093 224 COG0114 FumC, Fumarase Energy production and conversion 77459450 Common - regulatory protein GntR, HTH Pfl_3228 107 COG2186 FadR, Transcriptional regulators Transcription 77459572 Common - AMP-dependent synthetase and ligase Pfl_3350 210 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 77459455 Common - Aldehyde dehydrogenase Pfl_3233 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77458499 Common - hypothetical protein Pfl_2272 16 None None None 77458704 Common - NADH:flavin oxidoreductase/NADH oxidase Pfl_2479 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77460747 Common - hypothetical protein Pfl_4526 1 None None None 77458053 Common - Cytochrome C oxidase, mono-heme subunit/FixO Pfl_1826 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 77458286 Common - Transcriptional Regulator, RpiR family Pfl_2059 72 COG1737 RpiR, Transcriptional regulators Transcription 77457935 Common - Transthyretin Pfl_1708 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 77460261 Common - Short-chain dehydrogenase/reductase SDR Pfl_4040 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77456537 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_0309 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 77456971 Common - hypothetical protein Pfl_0744 17 None None None 77459551 Common - Glutathione S-transferase-like Pfl_3329 59 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77458086 Common - L-ornithine N5-oxygenase Pfl_1859 52 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 77459602 Common - Heavy Metal Sensor Signal Transduction Histidine Kinases (STHK) Pfl_3380 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77460084 Common - ApbE-like lipoprotein Pfl_3863 136 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 77460361 Common araG L-arabinose transporter ATP-binding protein Pfl_4140 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 77458697 Common - Twin-arginine translocation pathway signal Pfl_2472 109 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 77460976 Common - peptidyl-tRNA hydrolase Pfl_4755 215 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 77461417 Common - DNA-binding response regulator CreB Pfl_5196 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77456990 Common dnaK molecular chaperone DnaK Pfl_0763 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 77461594 Common - Thymidylate synthase Pfl_5373 136 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 77460347 Nonpathogen - hypothetical protein Pfl_4126 1 None None None 77460447 Common - Protein of unknown function DUF306 Pfl_4226 22 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 77460651 Common - Protein of unknown function DUF853 Pfl_4430 76 COG0433 COG0433, Predicted ATPase General function prediction only 77457244 Common - Cytochrome c assembly protein Pfl_1017 94 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 77460823 Common - Transcriptional Regulator, XRE family Pfl_4602 97 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 77457312 Common - Cold shock protein CspA Pfl_1085 178 COG1278 CspC, Cold shock proteins Transcription 77459533 Common - putative monovalent cation/H+ antiporter subunit C Pfl_3311 94 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 77458590 Common - Glucose-methanol-choline oxidoreductase Pfl_2363 91 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 77456956 Common - chemotaxis sensory transducer Pfl_0728 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77460032 Common - Copper-resistance protein CopA Pfl_3810 126 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 77459581 Common - General substrate transporter Pfl_3359 125 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77460143 Common - Alpha/beta hydrolase fold Pfl_3922 107 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77459016 Nonpathogen - hypothetical protein Pfl_2791 1 None None None 77458666 Common - Paraquat-inducible protein A Pfl_2441 50 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 77461497 Common - Major facilitator superfamily MFS_1 Pfl_5276 191 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461102 Common - Cobalamin synthesis protein/P47K Pfl_4881 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 77459782 Common - hypothetical protein Pfl_3560 1 None None None 77459420 Common - Sigma-24 (FecI) Pfl_3198 21 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77460796 Common - hypothetical protein Pfl_4575 36 COG4628 COG4628, Uncharacterized conserved protein Function unknown 77458162 Common pheS phenylalanyl-tRNA synthetase subunit alpha Pfl_1935 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 77458075 Common - TonB-dependent siderophore receptor Pfl_1848 106 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 77459151 Common - Phage integrase Pfl_2926 55 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 77456700 Common - hypothetical protein Pfl_0472 2 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 77460528 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_4307 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77460291 Common - UDP-glucose 6-dehydrogenase Pfl_4070 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 77459705 Nonpathogen - hypothetical protein Pfl_3483 1 None None None 77456912 Common - Transcriptional Regulator, LysR family Pfl_0684 71 COG0583 LysR, Transcriptional regulator Transcription 77461107 Common - Catalase-like Pfl_4886 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 77461720 Common dapF diaminopimelate epimerase Pfl_5499 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 77457680 Common - Beta-lactamase-like Pfl_1453 108 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77460018 Common - Sigma-24 (FecI) Pfl_3796 73 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77460972 Common lolB outer membrane lipoprotein LolB Pfl_4751 54 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 77461931 Common - General substrate transporter Pfl_5712 178 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77456785 Common - Short-chain dehydrogenase/reductase SDR Pfl_0557 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 77458522 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_2295 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77457007 Common rbfA ribosome-binding factor A Pfl_0780 183 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 77458904 Common - Metalloprotease inhibitor I38 Pfl_2679 4 None None None 77461866 Common - import inner membrane translocase, subunit Tim44 Pfl_5646 28 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 77457662 Common - Isochorismatase hydrolase Pfl_1435 85 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 77461585 Nonpathogen - hypothetical protein Pfl_5364 1 None None None 77461200 Common - Peptidase S16, lon-like Pfl_4979 54 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 77456461 Common - hypothetical protein Pfl_0233 68 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 77458368 Common - Transcriptional Regulator, DeoR family Pfl_2141 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 77457811 Common - Diaminohydroxyphosphoribosylaminopyrimidine deaminase, 5-amino-6-(5-phosphoribosylamino) uracil reductase Pfl_1584 89 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 77461437 Common - Rieske (2Fe-2S) region Pfl_5216 82 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 77459841 Common - hypothetical protein Pfl_3619 1 None None None 77459466 Common - Spermidine/putrescine ABC transporter ATP-binding subunit Pfl_3244 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77456690 Common aceF dihydrolipoamide acetyltransferase Pfl_0462 199 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 77457334 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Pfl_1107 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 77460034 Common - Copper resistance protein CopC Pfl_3812 27 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 77456250 Common - coproporphyrinogen III oxidase Pfl_0022 112 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 77461781 Common - Predicted signal transduction protein Pfl_5560 58 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 77459831 Common - NADH dehydrogenase subunit H Pfl_3609 187 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 77460786 Common - Leucine-rich repeat Pfl_4565 5 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 77460505 Common - Arginine N-succinyltransferase Pfl_4284 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 77456877 Common - Flp pilus assembly CpaB Pfl_0649 25 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 77456684 Nonpathogen - hypothetical protein Pfl_0456 1 None None None 77457698 Common - Patatin Pfl_1471 147 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 77456272 Nonpathogen - Protein of unknown function DUF1328 Pfl_0044 1 COG5487 COG5487, Small integral membrane protein Function unknown 77460763 Nonpathogen - hypothetical protein Pfl_4542 1 None None None 77458937 Common - Pyrrolo-quinoline quinone Pfl_2712 58 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 77457112 Common - Glycosyl transferase, group 1 Pfl_0885 208 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77459667 Common - GCN5-related N-acetyltransferase Pfl_3445 55 COG0456 RimI, Acetyltransferases General function prediction only 77460443 Common - Multi-sensor Hybrid Histidine Kinase Pfl_4222 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77459051 Common - Acyltransferase 3 Pfl_2826 73 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 77458225 Common - hypothetical protein Pfl_1998 52 None None None 77458295 Nonpathogen - hypothetical protein Pfl_2068 1 None None None 77461964 Common - regulatory proteins, IclR Pfl_2985 74 COG1414 IclR, Transcriptional regulator Transcription 77461599 Common - dinucleoside polyphosphate hydrolase Pfl_5378 114 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 77459936 Common - hypothetical protein Pfl_3714 1 None None None 77460013 Common - Filamentous haemagglutinin-like Pfl_3791 33 None None None 77461571 Common - hypothetical protein Pfl_5350 9 None None None 77459789 Common - Nucleoside diphosphate pyrophosphatase Pfl_3567 102 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 77456985 Common - hypothetical protein Pfl_0758 63 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 77459894 Common - Spore coat U Pfl_3672 13 COG5430 COG5430, Uncharacterized secreted protein Function unknown 77458710 Common - Acriflavin resistance protein Pfl_2485 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77458782 Common - hypothetical protein Pfl_2557 46 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 77461482 Nonpathogen - hypothetical protein Pfl_5261 1 None None None 77458125 Common - acetyl-CoA carboxylase subunit beta Pfl_1898 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 77459272 Nonpathogen - hypothetical protein Pfl_3050 1 None None None 77459479 Common - amidase Pfl_3257 211 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 161485594 Common - Betaine-aldehyde dehydrogenase Pfl_1049 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77456528 Common - 4-oxalocrotonate tautomerase Pfl_0300 40 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 77460877 Common - hypothetical protein Pfl_4656 7 None None None 77457628 Common - Glutamine amidotransferase, class-II Pfl_1401 74 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 77458987 Common - GAF Sensor Signal Transduction Histidine Kinase Pfl_2762 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 77456851 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_0623 215 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77457156 Common - Sigma-24 (FecI) Pfl_0929 123 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77460985 Common - Gamma-glutamyltranspeptidase Pfl_4764 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 77456600 Common - D-tyrosyl-tRNA deacylase Pfl_0372 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 77457326 Common glnD PII uridylyl-transferase Pfl_1099 124 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 77458982 Common - Hydrophobe/amphiphile efflux-1 HAE1 Pfl_2757 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77459741 Common - Two component Transcriptional regulator, Winged helix family Pfl_3519 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77456992 Common dapB dihydrodipicolinate reductase Pfl_0765 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 77460550 Common - GCN5-related N-acetyltransferase Pfl_4329 14 COG0456 RimI, Acetyltransferases General function prediction only 77459108 Common - hypothetical protein Pfl_2883 108 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77461469 Common - ATP-dependent RNA helicase DbpA Pfl_5248 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77457905 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Pfl_1678 166 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77461084 Common - hypothetical protein Pfl_4863 1 None None None 77461051 Common - hypothetical protein Pfl_4830 2 None None None 77457297 Common adk adenylate kinase Pfl_1070 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 77457518 Common - Peptidase M20D, amidohydrolase Pfl_1291 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 77458098 Common - Xanthine/uracil permease Pfl_1871 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 77457217 Common - permease YjgP/YjgQ Pfl_0990 78 COG0795 COG0795, Predicted permeases General function prediction only 77458073 Common - peptide synthase Pfl_1846 220 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77456697 Common - lipopolysaccharide core biosynthesis protein, putative Pfl_0469 7 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 77456257 Common - hypothetical protein Pfl_0029 17 COG3805 DodA, Aromatic ring-cleaving dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 77458377 Common - Molybdopterin biosynthetic protein B2 Pfl_2150 188 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 77461697 Common - Lysine exporter protein (LYSE/YGGA) Pfl_5476 122 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77457492 Common - Transcriptional Regulator, IclR family Pfl_1265 120 COG1414 IclR, Transcriptional regulator Transcription 77461351 Common - Nucleotidyl transferase Pfl_5130 220 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 77456705 Common - Glycosyl transferase, group 1 Pfl_0477 156 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77459760 Common - GCN5-related N-acetyltransferase Pfl_3538 1 COG3153 COG3153, Predicted acetyltransferase General function prediction only 77460997 Common - hypothetical protein Pfl_4776 1 None None None 77461738 Common - multidrug efflux protein NorA Pfl_5517 166 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 77457793 Common - CheA Signal Transduction Histidine Kinases (STHK) Pfl_1566 150 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 77459863 Common - UDP-2,3-diacylglucosamine hydrolase Pfl_3641 76 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 77461644 Common - hypothetical protein Pfl_5423 2 None None None 77456545 Common - hypothetical protein Pfl_0317 10 None None None 77458084 Common - Secretion protein HlyD Pfl_1857 162 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77458604 Common - Protein tyrosine/serine phosphatase Pfl_2377 52 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 77460293 Common rpsA 30S ribosomal protein S1 Pfl_4072 226 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 77457463 Common - FAD dependent oxidoreductase Pfl_1236 82 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 77459924 Nonpathogen - hypothetical protein Pfl_3702 1 None None None 77458345 Common - Binding-protein-dependent transport systems inner membrane component Pfl_2118 182 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 77461457 Common - Transcriptional Regulator, AraC family Pfl_5236 146 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77459628 Common - hypothetical protein Pfl_3406 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 77459542 Common - hypothetical protein Pfl_3320 1 None None None 77457749 Common - GCN5-related N-acetyltransferase Pfl_1522 33 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 77457167 Common - Protein of unknown function DUF1656 Pfl_0940 9 None None None 77459838 Nonpathogen - hypothetical protein Pfl_3616 1 None None None 77458167 Common - DNA helicase-related protein Pfl_1940 98 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 77456353 Common - hypothetical protein Pfl_0125 4 None None None 77459087 Common - Endoribonuclease L-PSP Pfl_2862 66 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77456505 Common - Thioesterase superfamily Pfl_0277 70 COG0824 FcbC, Predicted thioesterase General function prediction only 77459755 Common - Peptidase S58, DmpA Pfl_3533 53 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77459523 Common - hypothetical protein Pfl_3301 8 None None None 77461623 Common - Binding-protein-dependent transport systems inner membrane component Pfl_5402 209 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 77461318 Common - hypothetical protein Pfl_5097 1 None None None 77457103 Common - Protein of unknown function DUF34 Pfl_0876 101 COG0327 COG0327, Uncharacterized conserved protein Function unknown 77459689 Common - branched-chain amino acid aminotransferase Pfl_3467 199 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 77456647 Common - Protein of unknown function DUF891 Pfl_0419 42 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 77460963 Common - hypothetical protein Pfl_4742 3 None None None 77457934 Nonpathogen - hypothetical protein Pfl_1707 1 None None None 77460926 Common - Peptidase M10A and M12B, matrixin and adamalysin Pfl_4705 82 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 77458451 Common - Helix-turn-helix, AraC type Pfl_2224 126 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77459650 Common - Amidohydrolase 2 Pfl_3428 28 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 77459729 Common - Peptidylprolyl isomerase, FKBP-type Pfl_3507 72 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 77457987 Common - Alpha-L-glutamate ligase-related protein Pfl_1760 18 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 77461587 Common - FAD dependent oxidoreductase Pfl_5366 34 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77457371 Nonpathogen - hypothetical protein Pfl_1144 1 None None None 77456884 Common - acetyl-CoA acetyltransferase Pfl_0656 174 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77456755 Common hisZ ATP phosphoribosyltransferase regulatory subunit Pfl_0527 150 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 77460474 Common - CheW protein Pfl_4253 187 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77456946 Common - NAD(P)H dehydrogenase (quinone) Pfl_0718 46 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 77457597 Common - glycine cleavage system transcriptional repressor Pfl_1370 27 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 77459485 Common - luciferase-like Pfl_3263 125 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 77456863 Common - lipoprotein, putative Pfl_0635 13 None None None 77457099 Common - histidinol-phosphate aminotransferase Pfl_0872 229 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 77456409 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pfl_0181 208 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 77458622 Common - Secretion protein HlyD Pfl_2395 167 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77457147 Common - Iron-sulfur-dependent L-serine dehydratase single chain form Pfl_0920 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 77459878 Common - Isovaleryl-CoA dehydrogenase Pfl_3656 171 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77461293 Common rplP 50S ribosomal protein L16 Pfl_5072 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 77461580 Common - hypothetical protein Pfl_5359 7 None None None 77461563 Common - Transcriptional Regulator, AraC family Pfl_5342 104 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77457378 Common - Phage protein D-like Pfl_1151 29 COG3500 COG3500, Phage protein D General function prediction only 77461426 Common - Sarcosine oxidase, alpha subunit, heterotetrameric Pfl_5205 181 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 77461322 Common - HesB/YadR/YfhF Pfl_5101 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 77458256 Nonpathogen - hypothetical protein Pfl_2029 1 None None None 77458326 Common - hypothetical protein Pfl_2099 3 None None None 77457649 Common - Sigma-24 (FecI) Pfl_1422 101 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77461060 Common - Signal transduction histidine kinase, nitrogen specific, NtrB Pfl_4839 221 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 77456443 Common - Transcriptional Regulator, LysR family Pfl_0215 185 COG0583 LysR, Transcriptional regulator Transcription 77459210 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pfl_2987 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 77461566 Common - Aldehyde dehydrogenase Pfl_5345 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77458240 Nonpathogen - hypothetical protein Pfl_2013 1 None None None 77457841 Common kgd alpha-ketoglutarate decarboxylase Pfl_1614 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 77459477 Common - Bile acid:sodium symporter Pfl_3255 55 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 77460065 Common - Lipopolysaccharide biosynthesis Pfl_3844 151 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 77460639 Nonpathogen - hypothetical protein Pfl_4418 1 None None None 77457303 Common - hypothetical protein Pfl_1076 1 None None None 77458471 Common - hypothetical protein Pfl_2244 10 None None None 77459433 Common - von Willebrand factor, type A Pfl_3211 85 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 77458876 Common - HvnA; halovibrin Pfl_2651 5 None None None 77459775 Common - Aminotransferase, class I and II Pfl_3553 219 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 77461277 Common rpsD 30S ribosomal protein S4 Pfl_5056 221 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 77457693 Common - Protein of unknown function DUF454 Pfl_1466 56 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 77461214 Common - GCN5-related N-acetyltransferase Pfl_4993 26 COG0456 RimI, Acetyltransferases General function prediction only 77458114 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Pfl_1887 196 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77460480 Common - Glutamate--ammonia ligase Pfl_4259 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 77461342 Common - Iron-containing alcohol dehydrogenase Pfl_5121 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 77457578 Common - Protein of unknown function DUF112, transmembrane Pfl_1351 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 77456412 Common - RNA polymerase sigma factor Pfl_0184 170 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77458046 Common - hypothetical protein Pfl_1819 4 COG5555 COG5555, Cytolysin, a secreted calcineurin-like phosphatase Cell motility and secretion 77460337 Common - Electron transfer flavoprotein alpha and beta-subunits Pfl_4116 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 77456793 Common - hypothetical protein Pfl_0565 3 None None None 77458785 Common - Major facilitator superfamily MFS_1 Pfl_2560 126 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77459209 Common - General substrate transporter Pfl_2986 142 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461809 Common - hypothetical protein Pfl_5588 1 None None None 77461904 Common - ABC-2 Pfl_5684 115 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 77461515 Common - Malonate/sodium symporter MadM subunit Pfl_5294 11 COG2855 COG2855, Predicted membrane protein Function unknown 77459941 Common - regulatory protein GntR, HTH Pfl_3719 146 COG2186 FadR, Transcriptional regulators Transcription 77461285 Common rplF 50S ribosomal protein L6 Pfl_5064 240 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 77459028 Common - Twin-arginine translocation pathway signal Pfl_2803 64 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 77459251 Common - hypothetical protein Pfl_3029 23 None None None 77457053 Common - hypothetical protein Pfl_0826 2 None None None 77458860 Common - Xylulokinase Pfl_2635 178 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 77460330 Common - hypothetical protein Pfl_4109 15 None None None 77461929 Common - Response regulator receiver domain protein (CheY) Pfl_5709 210 COG4566 TtrR, Response regulator Signal transduction mechanisms 77461880 Common - ABC-3 Pfl_5660 180 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 77456611 Common hisE phosphoribosyl-ATP pyrophosphatase Pfl_0383 178 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 77458519 Common - hypothetical protein Pfl_2292 17 None None None 77457816 Common - Major facilitator superfamily MFS_1 Pfl_1589 90 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461489 Common - regulatory protein, ArsR Pfl_5268 112 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77458835 Common - Acyltransferase 3 Pfl_2610 81 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 77457074 Common - Peptidase U62, modulator of DNA gyrase Pfl_0847 154 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 77457202 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_0975 181 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77461839 Common - Aldose 1-epimerase Pfl_5618 53 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 77459326 Common - HesB/YadR/YfhF Pfl_3104 48 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 77457199 Common - Phospholipase/Carboxylesterase Pfl_0972 88 COG0400 COG0400, Predicted esterase General function prediction only 77456349 Common - TonB-dependent siderophore receptor Pfl_0121 116 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 77458935 Common - Protein of unknown function DUF181 Pfl_2710 50 COG1944 COG1944, Uncharacterized conserved protein Function unknown 77460198 Common - Possible Sensor with GAF domain Pfl_3977 81 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 77458493 Common - Amino acid adenylation Pfl_2266 215 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77456340 Common - NAD(P) transhydrogenase, beta subunit Pfl_0112 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 77459178 Common - ester cyclase-like Pfl_2953 15 COG5485 COG5485, Predicted ester cyclase General function prediction only 77459144 Common - Transcriptional Regulator, LysR family Pfl_2919 187 COG0583 LysR, Transcriptional regulator Transcription 77461162 Common - Pseudouridine synthase, Rsu Pfl_4941 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 77460159 Common dsbG disulfide isomerase/thiol-disulfide oxidase Pfl_3938 24 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 77458431 Nonpathogen - hypothetical protein Pfl_2204 1 None None None 77459255 Common - probable DNA primase Pfl_3033 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 77459231 Common - hypothetical protein Pfl_3009 20 None None None 77457962 Common - hypothetical protein Pfl_1735 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 77461533 Common - Holliday junction resolvase-like protein Pfl_5312 172 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 77456556 Common - hypothetical protein Pfl_0328 20 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77460495 Common - aspartate kinase Pfl_4274 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 77461249 Common - lipoprotein, putative Pfl_5028 21 COG3495 COG3495, Uncharacterized protein conserved in bacteria Function unknown 77461681 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_5460 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77461618 Common - S-type Pyocin Pfl_5397 8 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 77458161 Common rplT 50S ribosomal protein L20 Pfl_1934 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 77460131 Common - Transcriptional Regulator, LysR family Pfl_3910 189 COG0583 LysR, Transcriptional regulator Transcription 77460912 Common - Cytochrome b/b6-like Pfl_4691 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 77460154 Common - GCN5-related N-acetyltransferase Pfl_3933 5 COG0456 RimI, Acetyltransferases General function prediction only 77458869 Common - hypothetical protein Pfl_2644 1 None None None 77459335 Common - hypothetical protein Pfl_3113 53 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 77456335 Common - hypothetical protein Pfl_0107 2 None None None 77458741 Common - hypothetical protein Pfl_2516 16 None None None 77457359 Common - RNA polymerase sigma factor RpoS Pfl_1132 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 77458534 Common - Dihydrodipicolinate synthetase Pfl_2307 172 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 77457654 Common - ABC transporter-like Pfl_1427 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 77459191 Common - benzoate 1,2-dioxygenase ferredoxin reductase subunit Pfl_2966 133 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 77460959 Common - Short-chain dehydrogenase/reductase SDR Pfl_4738 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77458263 Nonpathogen - hypothetical protein Pfl_2036 2 None None None 77461779 Common - Transcriptional Regulator, LysR family Pfl_5558 189 COG0583 LysR, Transcriptional regulator Transcription 77459316 Common - Integral membrane protein TerC Pfl_3094 215 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 77457124 Common - flavodoxin Pfl_0897 55 COG0716 FldA, Flavodoxins Energy production and conversion 77457395 Common - tail fiber protein, putative Pfl_1168 7 None None None 77457267 Common - hypothetical protein Pfl_1040 13 COG3617 COG3617, Prophage antirepressor Transcription 77460745 Common - Glutaredoxin-like protein Pfl_4524 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 77456894 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_0666 174 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77457047 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_0820 54 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77459187 Common - Muconolactone delta-isomerase Pfl_2962 23 COG4829 CatC1, Muconolactone delta-isomerase Secondary metabolites biosynthesis, transport, and catabolism 77457357 Common pcm protein-L-isoaspartate O-methyltransferase Pfl_1130 156 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 77460467 Common - ribonucleotide-diphosphate reductase subunit alpha Pfl_4246 228 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 77460623 Common tolB translocation protein TolB Pfl_4402 159 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 77461132 Common - putative FAD-binding dehydrogenase Pfl_4911 64 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 77461081 Common rplU 50S ribosomal protein L21 Pfl_4860 202 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 77460407 Common - Transcriptional Regulator, LysR family Pfl_4186 108 COG0583 LysR, Transcriptional regulator Transcription 77461012 Common - lipoprotein, putative Pfl_4791 9 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 77456448 Common - Biopolymer transport protein ExbD/TolR Pfl_0220 103 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 77461961 Common - Protein of unknown function DUF37 Pfl_5744 182 COG0759 COG0759, Uncharacterized conserved protein Function unknown 77460113 Common - hypothetical protein Pfl_3892 11 COG3832 COG3832, Uncharacterized conserved protein Function unknown 77456654 Common - lipoprotein, putative Pfl_0426 2 None None None 77460857 Common - acetylornithine aminotransferase Pfl_4636 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 77461300 Common rplC 50S ribosomal protein L3 Pfl_5079 242 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 77456828 Nonpathogen - hypothetical protein Pfl_0600 4 None None None 77457082 Common - PTS IIA-like nitrogen-regulatory protein PtsN Pfl_0855 136 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 77461381 Common - pyrroloquinoline quinone biosynthesis protein PqqD Pfl_5160 14 None None None 77458719 Common - FAD-linked oxidoreductase Pfl_2494 36 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 77460670 Common - Enoyl-CoA hydratase/isomerase Pfl_4449 153 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77458306 Common - hypothetical protein Pfl_2079 39 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 77461398 Common - Phosphoribosyltransferase Pfl_5177 176 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 77459859 Common - Major facilitator superfamily MFS_1 Pfl_3637 27 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77457480 Common - hypothetical protein Pfl_1253 21 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 77457977 Common - hypothetical protein Pfl_1750 5 None None None 77460010 Common - Transcriptional Regulator, AraC family Pfl_3788 27 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77460489 Common - hypothetical protein Pfl_4268 1 None None None 77458016 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_1789 191 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77456435 Common - hypothetical protein Pfl_0207 5 COG3239 DesA, Fatty acid desaturase Lipid metabolism 77457863 Common - DNA replication initiation factor Pfl_1636 204 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 77461601 Common - hypothetical protein Pfl_5380 9 COG5528 COG5528, Predicted integral membrane protein Function unknown 77459168 Common - Molybdate ABC transporter, ATP-binding protein Pfl_2943 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 77461676 Common - Acyltransferase 3 Pfl_5455 88 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 77457700 Common - Protein of unknown function DUF6, transmembrane Pfl_1473 24 COG2962 RarD, Predicted permeases General function prediction only 77457060 Common - K+-dependent Na+/Ca+ exchanger protein Pfl_0833 112 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 77461172 Common - PhoH-like protein Pfl_4951 198 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 77458752 Common - Kelch repeat Pfl_2527 11 None None None 77456401 Common - Secretion protein HlyD Pfl_0173 156 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77461446 Common - Peptidase M19, renal dipeptidase Pfl_5225 100 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 77460904 Common - hypothetical protein Pfl_4683 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 77461608 Common - D-3-phosphoglycerate dehydrogenase Pfl_5387 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 77458624 Common - NADPH-dependent FMN reductase Pfl_2397 55 COG0431 COG0431, Predicted flavoprotein General function prediction only 77460051 Common - sugar transferase Pfl_3829 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 77457093 Common - Toluene tolerance Pfl_0866 42 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 77458358 Common - Integrase, catalytic region Pfl_2131 136 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 77457456 Common - pyridoxamine 5'-phosphate oxidase Pfl_1229 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 77458971 Common - Saccharopine dehydrogenase Pfl_2746 41 COG3268 COG3268, Uncharacterized conserved protein Function unknown 77457025 Common - TonB-dependent siderophore receptor Pfl_0798 113 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 77457153 Common - hypothetical protein Pfl_0926 15 None None None 77458725 Common - TonB-like Pfl_2500 7 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 77461079 Common obgE GTPase ObgE Pfl_4858 249 COG0536 Obg, Predicted GTPase General function prediction only 77459682 Common - Beta-lactamase-like Pfl_3460 192 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77459623 Common - ImpA-like Pfl_3401 26 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 77456366 Common - NLPA lipoprotein Pfl_0138 38 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 77461219 Common - hypothetical protein Pfl_4998 13 COG4676 COG4676, Uncharacterized protein conserved in bacteria Function unknown 77457087 Common - Protein of unknown function DUF1239 Pfl_0860 12 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 77456425 Common - Sulphate transport system permease protein 1 Pfl_0197 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 77461554 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase Pfl_5333 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 77460555 Common - aminotransferase Pfl_4334 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 77460615 Common - Glycine cleavage system T protein Pfl_4394 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 77460825 Common - hypothetical protein Pfl_4604 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 77457443 Common - SEC-C domain protein Pfl_1216 81 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 77461125 Common - Transcriptional Regulator, TetR family Pfl_4904 89 COG1309 AcrR, Transcriptional regulator Transcription 77459090 Common - Acyl-CoA dehydrogenase-like Pfl_2865 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77456856 Common - Rhs element Vgr protein Pfl_0628 46 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 77459661 Common - allantoate amidohydrolase Pfl_3439 86 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 77457286 Common - Peptide chain release factor 2 Pfl_1059 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 77458510 Nonpathogen - hypothetical protein Pfl_2283 1 None None None 77460756 Common - extracellular solute-binding protein, family 3 Pfl_4535 148 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77461750 Common - FAD dependent oxidoreductase Pfl_5529 117 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77456841 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Pfl_0613 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 77456902 Common - Sodium/calcium exchanger membrane region Pfl_0674 56 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 77461076 Common rpsT 30S ribosomal protein S20 Pfl_4855 140 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 77457141 Common - hypothetical protein Pfl_0914 28 COG2912 COG2912, Uncharacterized conserved protein Function unknown 77458247 Common - Lipopolysaccharide biosynthesis Pfl_2020 28 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 77456596 Common - N-formylglutamate deformylase Pfl_0368 57 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 77456873 Common - type II secretion system protein Pfl_0645 78 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 77457895 Common rdgC recombination associated protein Pfl_1668 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 77459096 Common - Transcriptional Regulator, AraC family Pfl_2871 73 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77460247 Common - lipoprotein, putative Pfl_4026 1 None None None 77460765 Common - hypothetical protein Pfl_4544 1 None None None 77457676 Common - hypothetical protein Pfl_1449 51 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77459377 Common - hypothetical protein Pfl_3155 32 None None None 77459636 Nonpathogen - hypothetical protein Pfl_3414 1 None None None 77456466 Common - monooxygenase, DszA family Pfl_0238 73 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 77457753 Common - hypothetical protein Pfl_1526 3 None None None 77460525 Common - Amidase Pfl_4304 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 77456609 Common tatB sec-independent translocase Pfl_0381 20 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 77457857 Common - chemotaxis sensory transducer Pfl_1630 135 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77461894 Common - hypothetical protein Pfl_5674 3 None None None 77457729 Common flgG flagellar basal body rod protein FlgG Pfl_1502 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 77458543 Common - Benzoate membrane transport protein Pfl_2316 60 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 77460176 Common - hypothetical protein Pfl_3955 1 None None None 77457543 Common - General substrate transporter Pfl_1316 134 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77460739 Common - OmpA/MotB Pfl_4518 34 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77461046 Common - hypothetical protein Pfl_4825 1 None None None 77461391 Common - Acyl-CoA dehydrogenase-like Pfl_5170 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77461182 Common - Lytic murein transglycosylase Pfl_4961 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 77461386 Common - Transcriptional Regulator, LysR family Pfl_5165 191 COG0583 LysR, Transcriptional regulator Transcription 77459637 Common - Rhs element Vgr protein Pfl_3415 69 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 77460126 Common - lipoprotein, putative Pfl_3905 2 None None None 77456941 Common - Transcriptional Regulator, MerR family Pfl_0713 112 COG0789 SoxR, Predicted transcriptional regulators Transcription 77461030 Common - Poly(A) polymerase, PcnB Pfl_4809 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 77461848 Common - Asparaginase/glutaminase Pfl_5627 134 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 77460426 Common - AMP-dependent synthetase and ligase Pfl_4205 219 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 77461368 Common rpsU 30S ribosomal protein S21 Pfl_5147 105 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 77456313 Common - Glucose-methanol-choline oxidoreductase Pfl_0085 67 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 77459605 Common - Cell wall hydrolase, SleB Pfl_3383 32 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 77461923 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_5703 203 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77461559 Common - Peptidase M16-like Pfl_5338 197 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 77456800 Common - Protein of unknown function DUF6, transmembrane Pfl_0572 59 None None None 77458568 Common - Oxidoreductase, molybdopterin binding Pfl_2341 131 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 77460104 Common - Lytic transglycosylase, catalytic Pfl_3883 168 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 77461772 Common - (p)ppGpp synthetase I (GTP pyrophosphokinase), SpoT/RelA Pfl_5551 208 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 77458068 Nonpathogen - Terpene synthase, metal-binding Pfl_1841 11 None None None 77460662 Common - hypothetical protein Pfl_4441 4 None None None 77458828 Common - Protein of unknown function DUF1294 Pfl_2603 36 COG3326 COG3326, Predicted membrane protein Function unknown 77456266 Common - ABC transporter-like Pfl_0038 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 77459113 Nonpathogen - hypothetical protein Pfl_2888 1 None None None 77456760 Common - 3'-5' exoribonuclease, VacB and RNase II Pfl_0532 198 COG0557 VacB, Exoribonuclease R Transcription 77458743 Common - Heat shock protein DnaJ-like Pfl_2518 11 None None None 77459795 Common - hypothetical protein Pfl_3573 1 None None None 77460352 Common - Metal dependent phosphohydrolase, HD region Pfl_4131 65 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 77458028 Common ligA NAD-dependent DNA ligase LigA Pfl_1801 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 77458391 Common - Lysine exporter protein (LYSE/YGGA) Pfl_2164 59 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77458579 Common - Radical SAM Pfl_2352 172 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 77460543 Common - transmembrane pair Pfl_4322 41 COG4125 COG4125, Predicted membrane protein Function unknown 77456374 Common - hypothetical protein Pfl_0146 47 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77458009 Common - Protein serine/threonine phosphatase Pfl_1782 152 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 77459674 Common - NAD-dependent epimerase/dehydratase Pfl_3452 108 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77460629 Common ruvA Holliday junction DNA helicase motor protein Pfl_4408 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 77457589 Common algU RNA polymerase sigma factor AlgU Pfl_1362 174 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77459370 Common - Flavin reductase-like, FMN-binding Pfl_3148 88 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 77460843 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase Pfl_4622 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 77460203 Common - methionine sulfoxide reductase B Pfl_3982 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 77458182 Common - Pirin-like Pfl_1955 148 COG1741 COG1741, Pirin-related protein General function prediction only 77458191 Common - DoxX Pfl_1964 7 COG2259 COG2259, Predicted membrane protein Function unknown 77458198 Common - hypothetical protein Pfl_1971 5 COG4907 COG4907, Predicted membrane protein Function unknown 77458561 Common - 2OG-Fe(II) oxygenase Pfl_2334 54 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 77459767 Common - hypothetical protein Pfl_3545 3 None None None 77461757 Common rpmG 50S ribosomal protein L33 Pfl_5536 139 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 77461139 Common - Histone deacetylase superfamily Pfl_4918 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 77461830 Common - Peptidase M23B Pfl_5609 177 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 77456846 Common - acetyl-CoA carboxylase biotin carboxylase subunit Pfl_0618 233 COG0439 AccC, Biotin carboxylase Lipid metabolism 77458991 Common - NADP oxidoreductase, coenzyme F420-dependent Pfl_2766 46 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 77456669 Common - hypothetical protein Pfl_0441 37 None None None 77458893 Common - hypothetical protein Pfl_2668 1 None None None 77457915 Common - MscS Mechanosensitive ion channel Pfl_1688 109 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77458694 Common - Transcriptional Regulator, AraC family Pfl_2469 56 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77458037 Common - adenine phosphoribosyltransferase Pfl_1810 186 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 77461665 Common - flagellar basal body-associated protein FliL-like protein Pfl_5444 19 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 77460183 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A Pfl_3962 120 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 77457341 Common lpxB lipid-A-disaccharide synthase Pfl_1114 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 77457386 Common - Bacteriophage Mu P Pfl_1159 21 COG4379 COG4379, Mu-like prophage tail protein gpP General function prediction only 77459902 Common - General substrate transporter Pfl_3680 76 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77456735 Common - hypothetical protein Pfl_0507 12 None None None 77460707 Common - Superoxide dismutase Pfl_4486 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 77457507 Common - Secretion protein HlyD Pfl_1280 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77459806 Common - recombination factor protein RarA Pfl_3584 234 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 77458602 Common - hypothetical protein Pfl_2375 27 COG5496 COG5496, Predicted thioesterase General function prediction only 77459293 Common - Alpha/beta hydrolase fold Pfl_3071 20 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 77460232 Common - outer membrane lipoprotein OprI Pfl_4011 1 None None None 77460717 Common - hypothetical protein Pfl_4496 11 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77456253 Common - Substrate-binding region of ABC-type glycine betaine transport system Pfl_0025 63 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 77461151 Common - Binding-protein-dependent transport systems inner membrane component Pfl_4930 190 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 77461490 Common - S-adenosylmethionine synthetase Pfl_5269 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 77459909 Common - NADH:flavin oxidoreductase/NADH oxidase Pfl_3687 208 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77460531 Common - Transcriptional Regulator, LysR family Pfl_4310 114 COG0583 LysR, Transcriptional regulator Transcription 77460864 Common - Endoribonuclease L-PSP Pfl_4643 90 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77457015 Common - AmpE Pfl_0788 20 COG3725 AmpE, Membrane protein required for beta-lactamase induction Defense mechanisms 77461804 Common - Transcriptional Regulator, Fis family Pfl_5583 172 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 77459413 Nonpathogen - hypothetical protein Pfl_3191 2 None None None 77458685 Common - Transcriptional Regulator, LysR family Pfl_2460 109 COG0583 LysR, Transcriptional regulator Transcription 77460620 Common - Radical SAM Pfl_4399 172 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 77461311 Common rplK 50S ribosomal protein L11 Pfl_5090 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 77460800 Common - Peptidase S16, ATP-dependent protease La Pfl_4579 212 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 77456235 Common - Phospholipid/glycerol acyltransferase Pfl_0007 130 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 77457870 Common - Nitroreductase Pfl_1643 112 COG0778 NfnB, Nitroreductase Energy production and conversion 77456837 Common - hypothetical protein Pfl_0609 4 None None None 77460595 Common glk glucokinase Pfl_4374 90 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 77458388 Common - Heme oxygenase Pfl_2161 18 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 77457877 Common cobS cobalamin synthase Pfl_1650 23 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 77459744 Common - Short-chain dehydrogenase/reductase SDR Pfl_3522 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77458884 Common - Secretion protein HlyD Pfl_2659 162 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77459169 Common - DNA topoisomerase, type I, putative Pfl_2944 45 COG3569 COG3569, Topoisomerase IB DNA replication, recombination, and repair 77458444 Common glcF glycolate oxidase iron-sulfur subunit Pfl_2217 172 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 77458005 Common - uroporphyrin-III C-methyltransferase Pfl_1778 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 77461711 Common - Glutathione S-transferase-like Pfl_5490 58 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77460058 Common - hypothetical protein Pfl_3837 2 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 77456664 Common - AMP-dependent synthetase and ligase Pfl_0436 100 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 77460927 Common - ATP-dependent transcriptional regulator, MalT related, LuxR family Pfl_4706 117 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 77456240 Common - lipid A biosynthesis lauroyl acyltransferase Pfl_0012 111 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 77459962 Common - TonB-dependent receptor Pfl_3740 89 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77460494 Common - Carbon storage regulator, CsrA Pfl_4273 76 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 77457401 Common - CinA-like Pfl_1174 191 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 77460227 Common - 2-dehydropantoate 2-reductase Pfl_4006 64 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 77461588 Common - extracellular solute-binding protein, family 1 Pfl_5367 110 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 77458030 Common - hypothetical protein Pfl_1803 3 None None None 77459765 Common - hypothetical protein Pfl_3543 20 COG4551 COG4551, Predicted protein tyrosine phosphatase General function prediction only 77460391 Common - Ferredoxin Pfl_4170 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 77458792 Common - Malate/L-lactate dehydrogenase Pfl_2567 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 77459439 Common - exonuclease SbcC Pfl_3217 142 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 77459665 Common - dihydropyrimidine dehydrogenase Pfl_3443 149 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 77459076 Common - Transcriptional Regulator, LysR family Pfl_2851 131 COG0583 LysR, Transcriptional regulator Transcription 77460200 Common - Histidine Kinase Pfl_3979 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77460408 Common - metal-dependent hydrolase Pfl_4187 64 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 77458746 Common - Secretion protein HlyD Pfl_2521 160 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77458592 Common - Catalase-like Pfl_2365 75 COG0753 KatE, Catalase Inorganic ion transport and metabolism 77459807 Common lolA outer-membrane lipoprotein carrier protein Pfl_3585 84 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 77459428 Common - NAD-glutamate dehydrogenase Pfl_3206 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 77460787 Common - hypothetical protein Pfl_4566 3 None None None 77456875 Common - pilus assembly protein CpaE Pfl_0647 40 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 77458599 Common - extracellular solute-binding protein, family 1 Pfl_2372 131 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77461714 Common cyaA adenylate cyclase Pfl_5493 25 COG3072 CyaA, Adenylate cyclase Nucleotide transport and metabolism 77459189 Common - hypothetical protein Pfl_2964 186 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77460384 Common - Peptidase S49, SppA Pfl_4163 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 77459432 Common - hypothetical protein Pfl_3210 1 None None None 77457345 Common - hypothetical protein Pfl_1118 210 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 77461120 Common - hypothetical protein Pfl_4899 7 None None None 77457855 Common - OsmC-like protein Pfl_1628 40 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77461405 Common - Response regulator receiver domain protein (CheY) Pfl_5184 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77460188 Common - Sodium/hydrogen exchanger Pfl_3967 173 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 77460627 Common - 4-hydroxybenzoyl-CoA thioesterase Pfl_4406 135 COG0824 FcbC, Predicted thioesterase General function prediction only 77461274 Common - Catalase-like Pfl_5053 128 COG0753 KatE, Catalase Inorganic ion transport and metabolism 77461363 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase Pfl_5142 191 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 77456594 Common - histidine ammonia-lyase Pfl_0366 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 77459969 Common - hypothetical protein Pfl_3747 32 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 77460674 Common - Salmonella virulence plasmid 65kDa B protein Pfl_4453 15 None None None 77459539 Common - hypothetical protein Pfl_3317 1 None None None 77460758 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_4537 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77459603 Common - Major facilitator superfamily MFS_1 Pfl_3381 177 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77459193 Common - ring hydroxylating dioxygenase, alpha subunit Pfl_2968 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 77460014 Common - Hemolysin activator HlyB Pfl_3792 49 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 77461036 Common - hypothetical protein Pfl_4815 125 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 77460723 Common groES co-chaperonin GroES Pfl_4502 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 77461837 Common - General substrate transporter Pfl_5616 160 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77460401 Common - ABC-2 Pfl_4180 161 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 77459241 Common - hypothetical protein Pfl_3019 19 None None None 77459750 Common - HAD-superfamily hydrolase subfamily IA, variant 1 and 3 Pfl_3528 141 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 77456375 Common - Peptidase M50 Pfl_0147 30 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77460115 Common - Protein of unknown function DUF1311 Pfl_3894 34 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 77459111 Common - Predicted transmembrane transcriptional regulator (anti-Sigma-factor) Pfl_2886 8 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 77459951 Common - Protein of unknown function DUF81 Pfl_3729 114 COG0730 COG0730, Predicted permeases General function prediction only 77457330 Common pyrH uridylate kinase Pfl_1103 236 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 77456652 Common - hypothetical protein Pfl_0424 25 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 77456718 Common - 3-deoxy-D-manno-octulosonic-acid transferase Pfl_0490 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 77460433 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase Pfl_4212 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 77459929 Common - Transcriptional Regulator, LysR family Pfl_3707 170 COG0583 LysR, Transcriptional regulator Transcription 77457246 Common rpsP 30S ribosomal protein S16 Pfl_1019 207 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 77456668 Common - Phospholipid/glycerol acyltransferase Pfl_0440 91 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 77461270 Common - single-strand DNA-binding protein Pfl_5049 212 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 77457603 Common - hypothetical protein Pfl_1376 30 None None None 77457872 Common - threonine-phosphate decarboxylase Pfl_1645 79 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 77459530 Common - Transcriptional Regulator, XRE family with Cupin sensor domain Pfl_3308 94 COG1396 HipB, Predicted transcriptional regulators Transcription 77460859 Common - GCN5-related N-acetyltransferase Pfl_4638 15 COG0456 RimI, Acetyltransferases General function prediction only 77456722 Common - lipoprotein, putative Pfl_0494 12 None None None 77460822 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Pfl_4601 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 77457106 Common - Phospholipid/glycerol acyltransferase Pfl_0879 30 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 77457458 Common - Rickettsia 17 kDa surface antigen Pfl_1231 21 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 77461754 Common - Major facilitator superfamily MFS_1 Pfl_5533 86 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 77461824 Common - Chorismate lyase Pfl_5603 47 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 77460413 Common - chemotaxis sensory transducer Pfl_4192 123 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77459058 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_2833 210 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456263 Common - Peptidase M16-like Pfl_0035 37 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 77457415 Common - Protein of unknown function DUF1456 Pfl_1188 31 COG4807 COG4807, Uncharacterized protein conserved in bacteria Function unknown 77456711 Common - Adenylylsulfate kinase Pfl_0483 144 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 77459270 Common - hypothetical protein Pfl_3048 3 None None None 77459608 Common - Cytochrome bd ubiquinol oxidase, subunit I Pfl_3386 165 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 77461359 Common glpE thiosulfate sulfurtransferase Pfl_5138 89 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 77457218 Common - permease YjgP/YjgQ Pfl_0991 118 COG0795 COG0795, Predicted permeases General function prediction only 77459325 Common - Precorrin-4 C11-methyltransferase region Pfl_3103 201 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 77456561 Common - phosphoglyceromutase Pfl_0333 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 77457591 Common - Sigma-E regulatory protein, MucB/RseB Pfl_1364 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 77458826 Common - chemotaxis sensory transducer Pfl_2601 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77459518 Common - Protein of unknown function DUF159 Pfl_3296 91 COG2135 COG2135, Uncharacterized conserved protein Function unknown 77460593 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_4372 173 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77458949 Nonpathogen - hypothetical protein Pfl_2724 1 None None None 77457937 Common - Lysine exporter protein (LYSE/YGGA) Pfl_1710 104 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77460060 Nonpathogen - hypothetical protein Pfl_3839 2 None None None 77456907 Common - inner-membrane translocator Pfl_0679 108 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 77460667 Common - hypothetical protein Pfl_4446 2 None None None 77459045 Common - Glycosyl transferase, group 1 Pfl_2820 189 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77456809 Common ureB urease subunit beta Pfl_0581 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 77457780 Nonpathogen - hypothetical protein Pfl_1553 1 None None None 77458549 Common - 2-chlorobenzoate 1,2-dioxygenase Pfl_2322 27 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 77457455 Common - OmpA/MotB Pfl_1228 128 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77460730 Common - Electron transport complex, RnfABCDGE type, B subunit Pfl_4509 98 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 77457135 Common - hypothetical protein Pfl_0908 1 COG3851 UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific Signal transduction mechanisms 77461521 Common - malonate decarboxylase subunit delta Pfl_5300 25 None None None 77456304 Common - cytochrome c oxidase, subunit III Pfl_0076 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 77460852 Nonpathogen - hypothetical protein Pfl_4631 1 None None None 77457088 Common - Phosphatase kdsC Pfl_0861 107 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 77459493 Common - Predicted transcriptional regulator Pfl_3271 143 COG1733 COG1733, Predicted transcriptional regulators Transcription 77461384 Common - hypothetical protein Pfl_5163 27 COG0401 COG0401, Uncharacterized homolog of Blt101 Function unknown 77461887 Common - Heavy metal-(Cd/Co/Hg/Pb/Zn)-translocating P-type ATPase Pfl_5667 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 77460107 Common - erythronate-4-phosphate dehydrogenase Pfl_3886 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 77456399 Common - Fusaric acid resistance protein conserved region Pfl_0171 56 COG1289 COG1289, Predicted membrane protein Function unknown 77460251 Common - Osmosensitive K+ channel Signal Transduction Histidine Kinase Pfl_4030 218 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 77460818 Common engA GTP-binding protein EngA Pfl_4597 236 COG1160 COG1160, Predicted GTPases General function prediction only 161485595 Common - ATP-dependent RNA helicase RhlB Pfl_0971 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77459378 Common - hypothetical protein Pfl_3156 62 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 77456428 Common - Transthyretin Pfl_0200 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 77461387 Common - Acyl-CoA dehydrogenase-like Pfl_5166 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77458215 Common - hypothetical protein Pfl_1988 13 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77458397 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_2170 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77459634 Common - probable ClpA/B-type protease Pfl_3412 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 77461435 Nonpathogen - hypothetical protein Pfl_5214 1 None None None 77456316 Common - Oligopeptidase A Pfl_0088 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 77456703 Common - Mig-14 Pfl_0475 5 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 77459877 Common - acyl-CoA synthetase Pfl_3655 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77458650 Nonpathogen - hypothetical protein Pfl_2425 1 None None None 77459162 Common - 2OG-Fe(II) oxygenase Pfl_2937 59 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 77456806 Common - hypothetical protein Pfl_0578 18 None None None 77458264 Nonpathogen - hypothetical protein Pfl_2037 1 None None None 77461773 Common - YjgF-like protein Pfl_5552 188 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77456608 Common - Sec-independent periplasmic protein translocase Pfl_0380 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 77457648 Common - 3-oxoacyl-(acyl carrier protein) synthase III Pfl_1421 200 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 77461427 Common - Sarcosine oxidase, delta subunit, heterotetrameric Pfl_5206 33 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 77459658 Common - Sigma-24 (FecI) Pfl_3436 62 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77456824 Common - TonB-dependent copper receptor Pfl_0596 106 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 77460831 Common - Iron-sulphur cluster assembly protein IscA Pfl_4610 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 77461057 Common - Pseudouridine synthase, RluD Pfl_4836 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 77457036 Common dppF dipeptide transporter ATP-binding subunit Pfl_0809 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 77460638 Common - Histidine triad (HIT) protein Pfl_4417 65 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 77458513 Common - hypothetical protein Pfl_2286 1 None None None 77459854 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3632 152 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 77458721 Common - hypothetical protein Pfl_2496 13 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 77460804 Common - Methyltransferase, putative Pfl_4583 59 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 77459759 Common - Phenylacetic acid degradation-like protein Pfl_3537 16 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 77456857 Nonpathogen - hypothetical protein Pfl_0629 1 None None None 77460883 Common - Acriflavin resistance protein Pfl_4662 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77456848 Common - 3-dehydroquinate dehydratase Pfl_0620 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 77456843 Common - Dihydrouridine synthase TIM-barrel protein nifR3 Pfl_0615 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 77460710 Common - Protein of unknown function DUF1111 Pfl_4489 49 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 77459007 Common - Transcriptional Regulator, LysR family Pfl_2782 105 COG0583 LysR, Transcriptional regulator Transcription 77457398 Nonpathogen - hypothetical protein Pfl_1171 1 None None None 77461349 Common - hypothetical protein Pfl_5128 7 None None None 77460660 Common - RDD Pfl_4439 28 COG1714 COG1714, Predicted membrane protein/domain Function unknown 77461379 Common - pyrroloquinoline quinone biosynthesis protein PqqB Pfl_5158 35 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 77457890 Common - hypothetical protein Pfl_1663 16 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 77460241 Common - Lytic transglycosylase, catalytic Pfl_4020 94 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 77457284 Common - chemotaxis-specific methylesterase Pfl_1057 202 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 77458881 Common - Secretion protein HlyD Pfl_2656 162 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77459774 Common - Cytochrome c, class I Pfl_3552 59 COG3474 COG3474, Cytochrome c2 Energy production and conversion 77457979 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Pfl_1752 164 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 77457716 Common - chromosome segregation and condensation protein ScpA Pfl_1489 145 COG1354 COG1354, Uncharacterized conserved protein Function unknown 77460742 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Pfl_4521 218 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77461374 Common - Transcriptional Regulator, AsnC family Pfl_5153 149 COG1522 Lrp, Transcriptional regulators Transcription 77460286 Common - ABC transporter-like Pfl_4065 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 77458659 Common - Phosphonate-binding periplasmic protein Pfl_2434 99 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 77459660 Common - hypothetical protein Pfl_3438 11 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 77460953 Common - FAD dependent oxidoreductase Pfl_4732 40 COG3380 COG3380, Predicted NAD/FAD-dependent oxidoreductase General function prediction only 77456963 Common - Tellurite resistance protein TehB Pfl_0736 67 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 77458074 Common - Amino acid adenylation Pfl_1847 219 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77458629 Common - hypothetical protein Pfl_2402 51 COG0622 COG0622, Predicted phosphoesterase General function prediction only 77461155 Common - Transcriptional Regulator, LysR family Pfl_4934 190 COG0583 LysR, Transcriptional regulator Transcription 77461709 Common - Transcriptional Regulator, LytR/AlgR family Pfl_5488 223 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 77456431 Common - Heavy Metal Sensor Signal Transduction Histidine Kinases (STHK) Pfl_0203 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77457776 Common fliP flagellar biosynthesis protein FliP Pfl_1549 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 77457024 Common - Flavodoxin/nitric oxide synthase Pfl_0797 115 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 77456573 Nonpathogen - hypothetical protein Pfl_0345 1 None None None 77460174 Common - MOSC Pfl_3953 76 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 77457478 Common - 6-phosphogluconate dehydrogenase, NAD-binding Pfl_1251 162 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 77456588 Common - urocanate hydratase Pfl_0360 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 77458751 Common - Short-chain dehydrogenase/reductase SDR Pfl_2526 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77457282 Common - CheW protein Pfl_1055 6 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77457362 Common - Possible phage repressor Pfl_1135 18 COG2932 COG2932, Predicted transcriptional regulator Transcription 77456968 Common - hypothetical protein Pfl_0741 8 None None None 77457064 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C Pfl_0837 143 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 77460933 Common - Methyltransferase small Pfl_4712 107 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 77456447 Common - MotA/TolQ/ExbB proton channel Pfl_0219 144 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 77460611 Common - Transcriptional Regulator, TyrR Pfl_4390 172 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 77461873 Common - hypothetical protein Pfl_5653 1 None None None 77459306 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pfl_3084 130 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 77457435 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_1208 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 77459508 Common - hypothetical protein Pfl_3286 2 None None None 77457897 Common - hypothetical protein Pfl_1670 22 None None None 77458917 Common - hypothetical protein Pfl_2692 2 None None None 77458064 Common - Alpha/beta hydrolase fold Pfl_1837 71 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77459371 Common dnaE2 error-prone DNA polymerase Pfl_3149 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 77457081 Common - hypothetical protein Pfl_0854 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 77458973 Common - Glycosyl hydrolase, BNR repeat Pfl_2748 39 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 77457441 Common - Glutathione S-transferase-like Pfl_1214 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77461013 Common - Penicillin-binding protein 1B Pfl_4792 201 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 77457080 Common - HPrNtr Pfl_0853 126 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 77456283 Common - GTPase EngB Pfl_0055 173 COG0218 COG0218, Predicted GTPase General function prediction only 77458976 Common - Protein of unknown function DUF1329 Pfl_2751 17 None None None 77460703 Common - NAD-dependent epimerase/dehydratase Pfl_4482 210 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77458717 Common - Aldehyde dehydrogenase Pfl_2492 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77461903 Common - Mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Pfl_5683 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 77456489 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_0261 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77458695 Common - Short-chain dehydrogenase/reductase SDR Pfl_2470 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 77459513 Nonpathogen - hypothetical protein Pfl_3291 1 None None None 77460577 Common - MaoC-like dehydratase Pfl_4356 98 COG2030 MaoC, Acyl dehydratase Lipid metabolism 77461161 Common - hypothetical protein Pfl_4940 11 None None None 77461739 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Pfl_5518 174 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77459612 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_3390 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77461246 Common - hypothetical protein Pfl_5025 9 None None None 77459310 Common - Endoribonuclease L-PSP Pfl_3088 179 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77457306 Common - Secretion protein HlyD Pfl_1079 170 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77457679 Nonpathogen - hypothetical protein Pfl_1452 1 None None None 77461954 Common - F0F1 ATP synthase subunit I Pfl_5737 21 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 77459417 Common - General secretion pathway protein H Pfl_3195 7 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77457450 Common - hypothetical protein Pfl_1223 1 None None None 77460031 Nonpathogen - hypothetical protein Pfl_3809 1 None None None 77459038 Common - hypothetical protein Pfl_2813 17 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 77459410 Common - Animal peptidoglycan recognition protein PGRP Pfl_3188 3 None None None 77456794 Common - AsmA Pfl_0566 45 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 77460477 Common - FlgN Pfl_4256 1 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 77456836 Common - hypothetical protein Pfl_0608 7 None None None 77459998 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Pfl_3776 129 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 77458601 Common - Endoribonuclease L-PSP Pfl_2374 83 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77460335 Common - lipoprotein, putative Pfl_4114 2 None None None 77456527 Common - Transcriptional Regulator, LysR family Pfl_0299 155 COG0583 LysR, Transcriptional regulator Transcription 77457071 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pfl_0844 198 COG0388 COG0388, Predicted amidohydrolase General function prediction only 77458787 Common - hypothetical protein Pfl_2562 1 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 77460062 Common - Phosphoribosylaminoimidazole carboxylase Pfl_3841 4 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 77460130 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_3909 178 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77459302 Common - acetyl-CoA synthetase Pfl_3080 201 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 77461484 Common - lipoprotein, putative Pfl_5263 1 None None None 77460266 Common - transferase hexapeptide repeat Pfl_4045 161 COG1043 LpxA, Acyl- acyl carrier protein 77456761 Common - RNA methyltransferase TrmH, group 3 Pfl_0533 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 77457486 Common - Transcriptional Regulator, LysR family Pfl_1259 172 COG0583 LysR, Transcriptional regulator Transcription 77460114 Common - ADP-ribosylation/Crystallin J1 Pfl_3893 84 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 77461168 Common hemL glutamate-1-semialdehyde aminotransferase Pfl_4947 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 77461135 Common - hypothetical protein Pfl_4914 11 None None None 77458417 Common - Transcriptional Regulator, LysR family Pfl_2190 63 COG0583 LysR, Transcriptional regulator Transcription 77458863 Common - Binding-protein-dependent transport systems inner membrane component Pfl_2638 159 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 77459890 Common - Spore coat U Pfl_3668 19 COG5430 COG5430, Uncharacterized secreted protein Function unknown 77461857 Common - Outer membrane autotransporter barrel Pfl_5637 63 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 77456320 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Pfl_0092 160 COG0546 Gph, Predicted phosphatases General function prediction only 77461018 Common - Protein of unknown function DUF399 Pfl_4797 29 COG3016 PhuW, Uncharacterized iron-regulated protein Function unknown 77459800 Common - DsrC-like protein Pfl_3578 43 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 77458137 Common - GCN5-related N-acetyltransferase Pfl_1910 4 None None None 77459934 Common - Cupin region Pfl_3712 33 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 77460983 Common - Colicin immunity protein/pyocin immunity protein Pfl_4762 8 None None None 77459344 Common - hypothetical protein Pfl_3122 9 COG5654 COG5654, Uncharacterized conserved protein Function unknown 77457203 Common - ABC transporter-like Pfl_0976 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 77457886 Common - Protein of unknown function DUF195 Pfl_1659 147 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 77458900 Common - FAD dependent oxidoreductase Pfl_2675 115 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77457529 Common - Protein of unknown function DUF6, transmembrane Pfl_1302 62 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77457986 Common - para-aminobenzoate synthase component I Pfl_1759 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 77458842 Common - hypothetical protein Pfl_2617 78 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 77459065 Common - Phage integrase Pfl_2840 194 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 77458466 Common - Esterase/lipase/thioesterase Pfl_2239 122 COG0657 Aes, Esterase/lipase Lipid metabolism 77458169 Nonpathogen - hypothetical protein Pfl_1942 2 None None None 77458540 Common - Threonine synthase Pfl_2313 169 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 77458370 Common - Glutamine synthetase, catalytic region Pfl_2143 229 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 77457126 Common - LrgA Pfl_0899 17 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 77461014 Common - hypothetical protein Pfl_4793 57 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 77461217 Common - inorganic pyrophosphatase Pfl_4996 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 77461287 Common rpsN 30S ribosomal protein S14 Pfl_5066 203 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 77458146 Common - Periplasmic binding protein/LacI transcriptional regulator Pfl_1919 102 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 77457290 Common - hypothetical protein Pfl_1063 16 COG3930 COG3930, Uncharacterized protein conserved in bacteria Function unknown 77457702 Common - Metallophosphoesterase Pfl_1475 69 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 77458111 Common - hypothetical protein Pfl_1884 5 None None None 77460570 Common def peptide deformylase Pfl_4349 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 77457575 Common - Enoyl-CoA hydratase/isomerase Pfl_1348 123 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77458017 Common - Peptidase S13, D-Ala-D-Ala carboxypeptidase C Pfl_1790 104 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 77457787 Common flhA flagellar biosynthesis protein A Pfl_1560 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 77459319 Common - Magnesium chelatase, ChlI subunit Pfl_3097 67 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 77461542 Common - Protein of unknown function YGGT Pfl_5321 125 COG0762 COG0762, Predicted integral membrane protein Function unknown 77459953 Common - Aldose 1-epimerase Pfl_3731 97 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 77457146 Common - serine transporter Pfl_0919 37 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 77460614 Common - Iron-sulfur-dependent L-serine dehydratase single chain form Pfl_4393 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 77460453 Common - hypothetical protein Pfl_4232 160 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 77459574 Common - short chain dehydrogenase Pfl_3352 226 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77457016 Common - chemotaxis sensory transducer Pfl_0789 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77459119 Common - Hydrophobe/amphiphile efflux-1 HAE1 Pfl_2894 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77459381 Common - ABC transporter-like Pfl_3159 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 77458952 Common - Short-chain dehydrogenase/reductase SDR Pfl_2727 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77459707 Common - hypothetical protein Pfl_3485 6 None None None 77458387 Common - Lysine exporter protein (LYSE/YGGA) Pfl_2160 98 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77456649 Common - hypothetical protein Pfl_0421 13 None None None 77458253 Common - ABC transporter-like Pfl_2026 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 77459145 Common - Putative diguanylate phosphodiesterase (EAL domain) Pfl_2920 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77459881 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Pfl_3659 239 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 77461553 Common - Protein of unknown function DUF423 Pfl_5332 69 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 77457904 Nonpathogen - hypothetical protein Pfl_1677 2 None None None 77459136 Nonpathogen - hypothetical protein Pfl_2911 1 None None None 77460604 Common - L-carnitine dehydratase/bile acid-inducible protein F Pfl_4383 111 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 77460771 Common - Response regulator receiver domain protein (CheY) Pfl_4550 223 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 77457739 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Pfl_1512 161 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 77460863 Common - hypothetical protein Pfl_4642 1 None None None 77460158 Common - thiol:disulfide interchange protein DsbE, putative Pfl_3937 153 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 77461561 Common - hypothetical protein Pfl_5340 208 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 77457930 Common - ureidoglycolate hydrolase Pfl_1703 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 77458616 Common - Lysine exporter protein (LYSE/YGGA) Pfl_2389 74 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77458020 Common - Transcriptional Regulator, GntR family Pfl_1793 133 COG1802 GntR, Transcriptional regulators Transcription 77459752 Common - hypothetical protein Pfl_3530 134 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 77458496 Common - MbtH-like protein Pfl_2269 30 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 77461704 Common - Disulphide bond formation protein DsbB Pfl_5483 54 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 77456455 Common - ABC transporter-like Pfl_0227 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 77457827 Common - Transcriptional Regulator, TetR family Pfl_1600 111 COG1309 AcrR, Transcriptional regulator Transcription 77456236 Common - D,D-heptose 1,7-bisphosphate phosphatase Pfl_0008 129 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 77458141 Common - Siderophore-interacting protein Pfl_1914 62 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 77458192 Common - Antibiotic biosynthesis monooxygenase Pfl_1965 24 COG3224 COG3224, Uncharacterized protein conserved in bacteria Function unknown 77458700 Common - Major facilitator superfamily MFS_1 Pfl_2475 121 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77456334 Common - hypothetical protein Pfl_0106 10 None None None 77461310 Common rplA 50S ribosomal protein L1 Pfl_5089 244 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 77457744 Common - Glycosyl transferase, family 2 Pfl_1517 77 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 77457059 Common - Carboxymuconolactone decarboxylase Pfl_0832 89 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 77459746 Common - Transcriptional Regulator, LysR family Pfl_3524 189 COG0583 LysR, Transcriptional regulator Transcription 77458142 Common - Deoxyribonuclease I Pfl_1915 31 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 77461315 Common - hypothetical protein Pfl_5094 1 None None None 77461849 Nonpathogen - hypothetical protein Pfl_5629 1 None None None 77461513 Common - HylII Pfl_5292 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 77457376 Common - Phage protein U-like Pfl_1149 10 COG3499 COG3499, Phage protein U General function prediction only 77461145 Common - Exonuclease Pfl_4924 150 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 77457593 Common - Peptidase M48, Ste24p Pfl_1366 123 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 77458779 Common - chemotaxis sensory transducer Pfl_2554 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77457879 Common - Major facilitator superfamily MFS_1 Pfl_1652 72 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 77459722 Common - Resolvase-like Pfl_3500 58 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 77460129 Common - DSBA oxidoreductase Pfl_3908 48 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 77460037 Nonpathogen - hypothetical protein Pfl_3815 1 None None None 77461181 Common - hypothetical protein Pfl_4960 1 COG3036 COG3036, Uncharacterized protein conserved in bacteria Function unknown 77456403 Common - hypothetical protein Pfl_0175 1 None None None 77457353 Common - Putative esterase Pfl_1126 100 COG0627 COG0627, Predicted esterase General function prediction only 77460846 Common - Histidine Kinase Pfl_4625 202 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456295 Common - NLPA lipoprotein Pfl_0067 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 77459526 Common - hypothetical protein Pfl_3304 1 None None None 77461719 Common - Diaminopimelate decarboxylase Pfl_5498 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 77461003 Common - Paraquat-inducible protein A Pfl_4782 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 77456657 Common - Sodium/hydrogen exchanger Pfl_0429 4 None None None 77456503 Common - ATP-dependent DNA helicase RecQ Pfl_0275 237 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 77457157 Common - Putative FecR Pfl_0930 47 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77458930 Common - hypothetical protein Pfl_2705 12 None None None 77460360 Common araH L-arabinose transporter permease protein Pfl_4139 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 77457910 Common - Binding-protein-dependent transport systems inner membrane component Pfl_1683 134 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 77456498 Common - hypothetical protein Pfl_0270 25 None None None 77458025 Common - Transcriptional Regulator, GntR family Pfl_1798 105 COG1802 GntR, Transcriptional regulators Transcription 77459023 Common - General substrate transporter Pfl_2798 163 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461945 Common - UDP-N-acetylglucosamine pyrophosphorylase Pfl_5728 233 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 77458833 Common - hypothetical protein Pfl_2608 26 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77456256 Common - hypothetical protein Pfl_0028 10 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 77457299 Common - hypothetical protein Pfl_1072 1 None None None 77456865 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Pfl_0637 199 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77459259 Common - Fimbrial protein Pfl_3037 12 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 77460960 Common - Amine oxidase Pfl_4739 66 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 77460656 Common - hypothetical protein Pfl_4435 1 None None None 77457335 Common - Peptidase M50, putative membrane-associated zinc metallopeptidase Pfl_1108 210 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 77459861 Common - glutaminyl-tRNA synthetase Pfl_3639 245 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 77458164 Common ihfA integration host factor subunit alpha Pfl_1937 208 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 77460464 Common - 4'-phosphopantetheinyl transferase Pfl_4243 36 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 77457236 Common - NUDIX hydrolase Pfl_1009 107 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 77459385 Common - hypothetical protein Pfl_3163 219 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 77460556 Common - Gluconate transporter Pfl_4335 76 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 77459794 Common - hypothetical protein Pfl_3572 1 None None None 77460955 Common - Protein of unknown function DUF523 Pfl_4734 61 COG3272 COG3272, Uncharacterized conserved protein Function unknown 77460911 Common - ubiquinol-cytochrome c reductase cytochrome c1 subunit Pfl_4690 44 COG2857 CYT1, Cytochrome c1 Energy production and conversion 77460050 Common - Response regulator receiver domain protein (CheY) Pfl_3828 17 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77461473 Common - GCN5-related N-acetyltransferase Pfl_5252 86 COG2153 ElaA, Predicted acyltransferase General function prediction only 77461732 Common - possible methyltransferase Pfl_5511 35 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77457210 Common ndpA nucleoid-associated protein NdpA Pfl_0983 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 77457391 Common - hypothetical protein Pfl_1164 4 None None None 77460124 Common - Peptidoglycan glycosyltransferase Pfl_3903 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 77461675 Common - Carboxylyase-like protein Pfl_5454 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 77457078 Common - Manganese and iron superoxide dismutase Pfl_0851 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 77459470 Common - Cysteine synthase Pfl_3248 222 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 77461127 Nonpathogen - hypothetical protein Pfl_4906 1 None None None 77461959 Common trmE tRNA modification GTPase TrmE Pfl_5742 227 COG0486 ThdF, Predicted GTPase General function prediction only 77460696 Common - Transcriptional Regulator, LysR family Pfl_4475 174 COG0583 LysR, Transcriptional regulator Transcription 77460905 Common - LppC putative lipoprotein Pfl_4684 48 COG3107 LppC, Putative lipoprotein General function prediction only 77461064 Common - type IV pilus-associated protein, putative Pfl_4843 34 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 77460075 Common - uncharacterized copper-binding protein Pfl_3854 27 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 77458342 Common - hypothetical protein Pfl_2115 2 None None None 77460257 Common - hypothetical protein Pfl_4036 41 COG3665 COG3665, Uncharacterized conserved protein Function unknown 77461544 Common metX homoserine O-acetyltransferase Pfl_5323 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 77457527 Common - Protein of unknown function DUF477 Pfl_1300 36 COG3762 COG3762, Predicted membrane protein Function unknown 77460429 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Pfl_4208 214 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 77460508 Common - Transcriptional Regulator, AraC family Pfl_4287 146 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77456661 Common - Phenylalanine/histidine ammonia-lyase Pfl_0433 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 77460646 Common - hypothetical protein Pfl_4425 174 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 77457223 Common recO DNA repair protein RecO Pfl_0996 64 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 77460146 Common - hypothetical protein Pfl_3925 10 None None None 77458320 Common - Phosphatidylcholine synthase Pfl_2093 24 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 77456457 Common - hypothetical protein Pfl_0229 42 COG4637 COG4637, Predicted ATPase General function prediction only 77461109 Common - Oxidoreductase FAD/NAD(P)-binding Pfl_4888 120 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 77461418 Common - Protein of unknown function DUF785 Pfl_5197 36 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 77457324 Common - hypothetical protein Pfl_1097 7 None None None 77458939 Common - Major royal jelly protein Pfl_2714 15 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 77461798 Common - hypothetical protein Pfl_5577 47 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 77459457 Common - Carboxymuconolactone decarboxylase Pfl_3235 84 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 77460545 Common - Transcriptional Regulator, LysR family Pfl_4324 181 COG0583 LysR, Transcriptional regulator Transcription 77459813 Common clpS ATP-dependent Clp protease adaptor protein ClpS Pfl_3591 116 COG2127 COG2127, Uncharacterized conserved protein Function unknown 77458116 Common - isopropylmalate isomerase large subunit Pfl_1889 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 77458189 Common - Transcriptional Regulator, LysR family Pfl_1962 89 COG0583 LysR, Transcriptional regulator Transcription 77456984 Common - Streptomyces cyclase/dehydrase Pfl_0757 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 77458669 Common - Protein of unknown function DUF861 Pfl_2444 20 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 77459784 Common - Transcriptional Regulator, TetR family Pfl_3562 84 COG1309 AcrR, Transcriptional regulator Transcription 77461354 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pfl_5133 167 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 77458292 Common - Succinylglutamate desuccinylase/aspartoacylase Pfl_2065 25 COG3608 COG3608, Predicted deacylase General function prediction only 77459893 Common - Spore coat U Pfl_3671 18 COG5430 COG5430, Uncharacterized secreted protein Function unknown 77457066 Common - Rod shape-determining protein MreC, subtype Pfl_0839 145 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 77461952 Common - F0F1 ATP synthase subunit C Pfl_5735 65 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 77459541 Common - Substrate-binding region of ABC-type glycine betaine transport system Pfl_3319 68 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 77460563 Nonpathogen - hypothetical protein Pfl_4342 1 None None None 77461400 Common - Twin-arginine translocation pathway signal Pfl_5179 74 COG3211 PhoX, Predicted phosphatase General function prediction only 77461458 Common - Iron-sulfur-dependent L-serine dehydratase single chain form Pfl_5237 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 77458091 Common - Hpt Sensor Hybrid Histidine Kinase Pfl_1864 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77458862 Common - ABC transporter-like Pfl_2637 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 77456329 Common - Protein of unknown function DUF883 Pfl_0101 1 COG4575 ElaB, Uncharacterized conserved protein Function unknown 77460455 Common - hypothetical protein Pfl_4234 25 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 77461462 Common - BCCT transporter Pfl_5241 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 77458907 Common - Type I secretion outer membrane protein, TolC Pfl_2682 140 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77459588 Nonpathogen - hypothetical protein Pfl_3366 1 None None None 77460080 Common - Lipoprotein releasing system, transmembrane protein, LolC/E family Pfl_3859 161 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 77456914 Common - Methylmalonate-semialdehyde dehydrogenase Pfl_0686 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77459843 Common - Heavy metal efflux pump CzcA Pfl_3621 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 77457830 Common - hypothetical protein Pfl_1603 7 None None None 77460092 Common - Transcriptional Regulator, TetR family Pfl_3871 90 COG1309 AcrR, Transcriptional regulator Transcription 77461531 Common - TonB-like Pfl_5310 34 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 77457049 Common - ABC transporter-like Pfl_0822 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 77458702 Common - Alpha/beta hydrolase fold Pfl_2477 162 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77460026 Nonpathogen - hypothetical protein Pfl_3804 1 None None None 77461298 Common rplW 50S ribosomal protein L23 Pfl_5077 216 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 77460914 Common rpsI 30S ribosomal protein S9 Pfl_4693 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 77461763 Common - Phosphomannomutase Pfl_5542 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 77461103 Common - Protein of unknown function DUF466 Pfl_4882 27 COG2879 COG2879, Uncharacterized small protein Function unknown 77460780 Common - Ferredoxin-dependent glutamate synthase Pfl_4559 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 77461579 Common - dihydroxy-acid dehydratase Pfl_5358 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 77457057 Common - D-galactarate dehydratase/Altronate hydrolase-like Pfl_0830 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 77457001 Common - Phosphoglucosamine mutase Pfl_0774 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 77460440 Common cysM cysteine synthase B Pfl_4219 230 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 77460538 Common - chemotaxis sensory transducer Pfl_4317 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77461157 Common - hypothetical protein Pfl_4936 4 None None None 77458282 Common - Amino acid permease-associated region Pfl_2055 183 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 77459206 Common - cytochrome c-type protein Pfl_2981 45 COG3245 CycB, Cytochrome c5 Energy production and conversion 77459673 Common - outer membrane porin Pfl_3451 9 None None None 77459314 Common - extracellular solute-binding protein, family 3 Pfl_3092 168 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77456293 Common - ABC transporter-like Pfl_0065 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 77457864 Common - NLP/P60 Pfl_1637 138 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 77460025 Common - Transcriptional Regulator, LysR family Pfl_3803 142 COG0583 LysR, Transcriptional regulator Transcription 77457992 Common - methylcitrate synthase Pfl_1765 194 COG0372 GltA, Citrate synthase Energy production and conversion 77457388 Common - Phage FluMu protein gp46 Pfl_1161 16 COG4381 COG4381, Mu-like prophage protein gp46 Function unknown 77457241 Common purT phosphoribosylglycinamide formyltransferase 2 Pfl_1014 201 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 77457343 Common dnaE DNA polymerase III subunit alpha Pfl_1116 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 77461591 Common - LysR, substrate-binding Pfl_5370 192 COG0583 LysR, Transcriptional regulator Transcription 77461496 Common - Protein of unknown function DUF6, transmembrane Pfl_5275 56 None None None 77461957 Common gidB glucose-inhibited division protein B Pfl_5740 204 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 77459619 Nonpathogen - hypothetical protein Pfl_3397 1 None None None 77460039 Common - PAAR Pfl_3817 4 COG4104 COG4104, Uncharacterized conserved protein Function unknown 77459939 Common - hypothetical protein Pfl_3717 126 COG0628 PerM, Predicted permease General function prediction only 77461083 Common - PhnA protein Pfl_4862 106 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 77458839 Common - hypothetical protein Pfl_2614 1 None None None 77460318 Common - Protein of unknown function DUF344 Pfl_4097 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 77458661 Common - Transcriptional Regulator, LysR family Pfl_2436 154 COG0583 LysR, Transcriptional regulator Transcription 77459901 Common - FAD dependent oxidoreductase Pfl_3679 113 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77458102 Common - excinuclease ABC subunit B Pfl_1875 225 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 77458649 Common - hypothetical protein Pfl_2424 3 None None None 77461097 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Pfl_4876 196 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77456382 Common - hypothetical protein Pfl_0154 2 None None None 77457272 Common - Binding-protein-dependent transport systems inner membrane component Pfl_1045 180 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 77458829 Common - hypothetical protein Pfl_2604 15 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 77457275 Common - extracellular solute-binding protein, family 1 Pfl_1048 121 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77459610 Common moaA molybdenum cofactor biosynthesis protein A Pfl_3388 199 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 77461467 Common - hypothetical protein Pfl_5246 61 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 77460799 Nonpathogen - hypothetical protein Pfl_4578 1 None None None 77458289 Common ftrA transcriptional activator FtrA Pfl_2062 142 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77459559 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_3337 188 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77461438 Common - hypothetical protein Pfl_5217 6 COG1409 Icc, Predicted phosphohydrolases General function prediction only 77460764 Common - Alpha/beta hydrolase fold Pfl_4543 80 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77460308 Common - hypothetical protein Pfl_4087 1 None None None 77461302 Common tuf elongation factor Tu Pfl_5081 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 77461734 Common - Glutamine amidotransferase class-I Pfl_5513 156 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 77461749 Common - hypothetical protein Pfl_5528 9 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 77460162 Common - extracytoplasmic-function sigma-70 factor PvdS Pfl_3941 69 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77459503 Common - FAD linked oxidase-like Pfl_3281 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 77458424 Common - Rhomboid-like protein Pfl_2197 60 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 77459180 Common - Transcriptional Regulator, TetR family Pfl_2955 104 COG1309 AcrR, Transcriptional regulator Transcription 77458845 Common - ecotin precursor Pfl_2620 23 COG4574 Eco, Serine protease inhibitor ecotin General function prediction only 77461115 Common - hypothetical protein Pfl_4894 133 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77458653 Common - hypothetical protein Pfl_2428 13 COG4694 COG4694, Uncharacterized protein conserved in bacteria Function unknown 77459295 Common - extracellular solute-binding protein, family 5 Pfl_3073 111 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 77459383 Common - nitrate ABC transporter, periplasmic nitrate-binding protein, putative Pfl_3161 87 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 77461639 Common - Taurine ABC transporter, periplasmic binding protein Pfl_5418 100 COG4521 TauA, ABC-type taurine transport system, periplasmic component Inorganic ion transport and metabolism 77459734 Common - Transcriptional Regulator, LysR family Pfl_3512 192 COG0583 LysR, Transcriptional regulator Transcription 77458584 Common - Citrate carrier protein Pfl_2357 29 COG3493 CitS, Na+/citrate symporter Energy production and conversion 77460523 Nonpathogen - hypothetical protein Pfl_4302 1 None None None 77457837 Common - Succinate dehydrogenase, cytochrome b subunit Pfl_1610 61 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 77459281 Common - Integrase, catalytic region Pfl_3059 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 77461578 Common - Major facilitator superfamily MFS_1 Pfl_5357 221 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77456277 Common - AmpD Pfl_0049 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 77459548 Common - chemotaxis sensory transducer Pfl_3326 108 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77459595 Common - glutaminase Pfl_3373 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 77458674 Common - Major facilitator superfamily MFS_1 Pfl_2449 64 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77457727 Common - Transcriptional Regulator, TyrR Pfl_1500 169 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 77456535 Common - Methyltransferase FkbM Pfl_0307 19 None None None 77459684 Common - Possible Transcriptional Regulator, AsnC family Pfl_3462 158 COG1522 Lrp, Transcriptional regulators Transcription 77461195 Common proA gamma-glutamyl phosphate reductase Pfl_4974 188 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 77458056 Nonpathogen - hypothetical protein Pfl_1829 1 None None None 77460295 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Pfl_4074 232 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 77456437 Common - ABC transporter-like Pfl_0209 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 77457318 Common - Fe-S metabolism associated SufE Pfl_1091 92 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 77457805 Common - Cytochrome c-type biogenesis protein CcmB Pfl_1578 55 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 77459175 Nonpathogen - hypothetical protein Pfl_2950 1 None None None 77458611 Common - Major facilitator superfamily MFS_1 Pfl_2384 73 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 77460592 Common - N-acylglucosamine 2-epimerase Pfl_4371 28 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 77458618 Common - hypothetical protein Pfl_2391 6 None None None 77459826 Common - NADH dehydrogenase subunit B Pfl_3604 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 77459498 Common - Aldehyde dehydrogenase Pfl_3276 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77456955 Nonpathogen - hypothetical protein Pfl_0727 1 None None None 77460472 Common flgB flagellar basal body rod protein FlgB Pfl_4251 86 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 77456463 Common - Binding-protein-dependent transport systems inner membrane component Pfl_0235 182 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 77457256 Common - Possible Sensor with PAS/PAC domain Pfl_1029 68 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77459970 Common - hypothetical protein Pfl_3748 3 None None None 77461912 Nonpathogen - hypothetical protein Pfl_5692 1 None None None 77456473 Common - D-cysteine desulfhydrase Pfl_0245 86 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 77461755 Common - Aldehyde dehydrogenase Pfl_5534 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77459288 Common uvrC excinuclease ABC subunit C Pfl_3066 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 77461433 Common - Protein of unknown function DUF796 Pfl_5212 28 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 77458576 Common - hypothetical protein Pfl_2349 2 None None None 77457625 Common - Cyclic nucleotide-binding (cNMP-BD) protein Pfl_1398 93 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 77460805 Common - Cytidine/deoxycytidylate deaminase, zinc-binding region Pfl_4584 219 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 77461788 Nonpathogen - hypothetical protein Pfl_5567 1 None None None 77456566 Common - hypothetical protein Pfl_0338 1 None None None 77461242 Common - hypothetical protein Pfl_5021 1 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 77460216 Common - Transcriptional Regulator, LysR family Pfl_3995 163 COG0583 LysR, Transcriptional regulator Transcription 77456521 Common - TonB-dependent siderophore receptor Pfl_0293 116 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 77458277 Common - glutamate carboxypeptidase Pfl_2050 164 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 77460354 Nonpathogen - hypothetical protein Pfl_4133 1 None None None 77456979 Common - Protein of unknown function DUF224, cysteine-rich region Pfl_0752 165 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 77459398 Common - General secretion pathway M protein Pfl_3176 3 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 77459094 Common - Short-chain dehydrogenase/reductase SDR Pfl_2869 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77459137 Common - hypothetical protein Pfl_2912 8 None None None 77456871 Common - hypothetical protein Pfl_0643 6 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 77458801 Common - agmatinase Pfl_2576 155 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 77456644 Common - General substrate transporter Pfl_0416 161 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77457248 Common trmD tRNA (guanine-N(1)-)-methyltransferase Pfl_1021 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 77461058 Common - competence lipoprotein ComL, putative Pfl_4837 122 COG4105 ComL, DNA uptake lipoprotein General function prediction only 77461791 Common - hypothetical protein Pfl_5570 9 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77460303 Common - phosphoglycolate phosphatase Pfl_4082 169 COG0546 Gph, Predicted phosphatases General function prediction only 77458620 Common - hypothetical protein Pfl_2393 3 None None None 77459948 Common - hypothetical protein Pfl_3726 9 None None None 77461451 Common - Substrate-binding region of ABC-type glycine betaine transport system Pfl_5230 62 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 77461569 Common coaD phosphopantetheine adenylyltransferase Pfl_5348 209 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 77458148 Common - inner-membrane translocator Pfl_1921 130 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 77460313 Common - hypothetical protein Pfl_4092 16 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 77458236 Nonpathogen - hypothetical protein Pfl_2009 1 None None None 77458818 Common - hypothetical protein Pfl_2593 19 None None None 77458776 Common - Alpha/beta hydrolase fold Pfl_2551 162 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77456441 Common - Taurine dioxygenase Pfl_0213 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 77461617 Common - Colicin immunity protein/pyocin immunity protein Pfl_5396 8 None None None 77456342 Common - NAD(P)(+) transhydrogenase (AB-specific) Pfl_0114 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 77461659 Common - 5-formyltetrahydrofolate cyclo-ligase Pfl_5438 72 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 77458925 Common - Formate dehydrogenase, gamma subunit Pfl_2700 63 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 77461504 Common - DEAD/DEAH box helicase-like Pfl_5283 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77460521 Common - Protein of unknown function DUF81 Pfl_4300 67 COG0730 COG0730, Predicted permeases General function prediction only 77460802 Common - YhhN-like Pfl_4581 11 COG3714 COG3714, Predicted membrane protein Function unknown 77458964 Common - Cytochrome c, class I Pfl_2739 61 COG2863 COG2863, Cytochrome c553 Energy production and conversion 77456306 Common - Cytochrome-c oxidase Pfl_0078 174 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 77459367 Common - extracellular solute-binding protein, family 1 Pfl_3145 126 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77461610 Common - extracellular solute-binding protein, family 3 Pfl_5389 119 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77461938 Common - transposition protein, TnsD-like protein Pfl_5721 14 None None None 77459886 Common - Cytochrome B561 Pfl_3664 29 COG3038 CybB, Cytochrome B561 Energy production and conversion 77456511 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Pfl_0283 41 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 77461307 Common rpoB DNA-directed RNA polymerase subunit beta Pfl_5086 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 77461227 Common - Polyprenyl synthetase Pfl_5006 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 77458270 Common - hypothetical protein Pfl_2043 3 None None None 77459159 Common - hypothetical protein Pfl_2934 3 None None None 77456799 Common - Alpha/beta hydrolase fold Pfl_0571 21 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 77456368 Common - Binding-protein-dependent transport systems inner membrane component Pfl_0140 148 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 77457736 Common - Hemolysin-type calcium-binding region Pfl_1509 89 None None None 77461212 Common - Ethanolamine ammonia lyase large subunit Pfl_4991 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 77460435 Common - hypothetical protein Pfl_4214 1 None None None 77458463 Common - General substrate transporter Pfl_2236 201 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77461174 Common - Transporter-associated region Pfl_4953 217 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 77457764 Common fliG flagellar motor switch protein G Pfl_1537 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 77460774 Common - Di-haem cytochrome c peroxidase Pfl_4553 93 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 77458586 Common - 3-isopropylmalate dehydratase small subunit region Pfl_2359 207 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 77457770 Common - Hpt domain protein Pfl_1543 25 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 77458132 Common - Twin-arginine translocation pathway signal Pfl_1905 106 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 77460980 Common - S-type Pyocin Pfl_4759 9 None None None 77456920 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_0692 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77461810 Nonpathogen - hypothetical protein Pfl_5589 1 None None None 77458506 Common - Two Component Transcriptional Regulator, LuxR family Pfl_2279 194 COG4566 TtrR, Response regulator Signal transduction mechanisms 77456578 Common - hypothetical protein Pfl_0350 29 COG5373 COG5373, Predicted membrane protein Function unknown 77459772 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_3550 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77461425 Common - Sarcosine oxidase, gamma subunit, heterotetrameric Pfl_5204 29 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 77461255 Common - Major facilitator superfamily MFS_1 Pfl_5034 193 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77457496 Common - beta-ketoadipyl CoA thiolase Pfl_1269 174 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77456629 Common rpmE 50S ribosomal protein L31 Pfl_0401 202 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 77460152 Common - MbtH-like protein Pfl_3931 31 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 77461726 Common - Ammonium transporter Pfl_5505 202 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 77456938 Common - Chorismate lyase Pfl_0710 31 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 77461237 Common ribH riboflavin synthase subunit beta Pfl_5016 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 77459712 Nonpathogen - hypothetical protein Pfl_3490 1 None None None 77461330 Common - S-adenosylmethionine decarboxylase Pfl_5109 32 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 77457610 Common - Transcriptional Regulator, LysR family Pfl_1383 122 COG0583 LysR, Transcriptional regulator Transcription 77458755 Common - 4Fe-4S ferredoxin, iron-sulfur binding Pfl_2530 77 COG0348 NapH, Polyferredoxin Energy production and conversion 77456636 Common - Pilus assembly protein, PilQ Pfl_0408 37 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 77461206 Common - Protein of unknown function DUF1375 Pfl_4985 1 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 77457406 Common - hypothetical protein Pfl_1179 1 None None None 77460002 Common - Carboxymuconolactone decarboxylase Pfl_3780 61 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 77460941 Common - hypothetical protein Pfl_4720 1 None None None 77456936 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_0708 129 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77457468 Common - hypothetical protein Pfl_1241 35 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 77457380 Common - hypothetical protein Pfl_1153 4 None None None 77457545 Common - Transcriptional Regulator, LysR family Pfl_1318 83 COG0583 LysR, Transcriptional regulator Transcription 77460511 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_4290 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 77461862 Common - Transcriptional Regulator, RpiR family Pfl_5642 87 COG1737 RpiR, Transcriptional regulators Transcription 77460873 Common - nitric oxide dioxygenase Pfl_4652 133 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 77458764 Common - LmbE-like protein Pfl_2539 20 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 77457054 Common - 5-dehydro-4-deoxyglucarate dehydratase Pfl_0827 226 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 77456675 Common - chemotaxis sensory transducer Pfl_0447 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77460019 Common - Putative FecR Pfl_3797 46 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77461548 Common - coproporphyrinogen III oxidase Pfl_5327 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 77457923 Common - lipid A biosynthesis lauroyl acyltransferase Pfl_1696 117 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 77459360 Common - Multi-sensor Hybrid Histidine Kinase Pfl_3138 220 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77457636 Common - ATPase associated with various cellular activities, AAA_5 Pfl_1409 100 COG0714 COG0714, MoxR-like ATPases General function prediction only 77457619 Common - hypothetical protein Pfl_1392 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 77459239 Common - hypothetical protein Pfl_3017 13 None None None 77460276 Common - Glycosyl transferase, family 2 Pfl_4055 57 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77458638 Common - hypothetical protein Pfl_2411 5 COG2105 COG2105, Uncharacterized conserved protein Function unknown 77459719 Nonpathogen - hypothetical protein Pfl_3497 1 None None None 77458630 Nonpathogen - hypothetical protein Pfl_2403 1 None None None 77459443 Common - hypothetical protein Pfl_3221 1 None None None 77461922 Nonpathogen - hypothetical protein Pfl_5702 1 None None None 77460487 Common - chemotaxis sensory transducer Pfl_4266 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77457535 Common - hypothetical protein Pfl_1308 117 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 77457958 Common - hypothetical protein Pfl_1731 1 None None None 77459960 Common - MotA/TolQ/ExbB proton channel Pfl_3738 144 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 77459967 Common - hypothetical protein Pfl_3745 14 None None None 77457668 Common - Protein of unknown function DUF899, thioredoxin-like Pfl_1441 29 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 77457941 Common - hypothetical protein Pfl_1714 20 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 77459643 Nonpathogen - hypothetical protein Pfl_3421 1 None None None 77459651 Common - Amidohydrolase 2 Pfl_3429 26 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 77461365 Common - Dihydroneopterin aldolase family Pfl_5144 50 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 77457179 Common - Membrane bound O-acyl transferase, MBOAT Pfl_0952 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 77460948 Common - hypoxanthine-guanine phosphoribosyltransferase Pfl_4727 118 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 77457559 Common - hypothetical protein Pfl_1332 21 COG1598 COG1598, Uncharacterized conserved protein Function unknown 77460046 Common - tRNA-dihydrouridine synthase A Pfl_3824 206 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 77459105 Common - Protein of unknown function DUF81 Pfl_2880 102 COG0730 COG0730, Predicted permeases General function prediction only 77456504 Common - 6-phosphogluconate dehydrogenase, NAD-binding Pfl_0276 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 77457999 Common - ribonuclease activity regulator protein RraA Pfl_1772 102 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 77457587 Common - L-aspartate oxidase Pfl_1360 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 77459046 Common - O-antigen polymerase Pfl_2821 20 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 77456931 Common - luciferase-like Pfl_0703 85 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 77458212 Common - hypothetical protein Pfl_1985 8 None None None 77458088 Common - MgtC/SapB transporter Pfl_1861 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 77458312 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_2085 204 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456749 Common mutL DNA mismatch repair protein Pfl_0521 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 77460893 Common murC UDP-N-acetylmuramate--L-alanine ligase Pfl_4672 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 77456970 Common - hypothetical protein Pfl_0743 22 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 77459552 Common - DNA alkylation repair enzyme-like Pfl_3330 37 COG4335 COG4335, DNA alkylation repair enzyme DNA replication, recombination, and repair 77457475 Common - Extracellular ligand-binding receptor Pfl_1248 146 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 77461029 Common - Response regulator receiver domain protein (CheY) Pfl_4808 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77460501 Common - hypothetical protein Pfl_4280 1 None None None 77458505 Common - hypothetical protein Pfl_2278 1 None None None 77456868 Common - Two Component Transcriptional Regulator, LuxR family Pfl_0640 222 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77456987 Common - Ferric uptake regulator (FUR) family Pfl_0760 187 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 77458159 Common infC translation initiation factor IF-3 Pfl_1932 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 77460987 Common - chemotaxis sensory transducer, Pas/Pac sensor Pfl_4766 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77458723 Common - MotA/TolQ/ExbB proton channel Pfl_2498 123 COG5306 COG5306, Uncharacterized conserved protein Function unknown 77457513 Common - Phospholipid/glycerol acyltransferase Pfl_1286 94 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 77458204 Common - Electron transport protein SCO1/SenC Pfl_1977 75 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 77458851 Common - hypothetical protein Pfl_2626 6 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 77461663 Common - ABC transporter-like Pfl_5442 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 77458832 Common - hypothetical protein Pfl_2607 46 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 77456831 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Pfl_0603 109 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 77458155 Common - hypothetical protein Pfl_1928 10 None None None 77458101 Common - aromatic amino acid aminotransferase Pfl_1874 73 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 77456516 Common - Histidine Kinase Pfl_0288 195 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77460326 Common - hypothetical protein Pfl_4105 37 COG1742 COG1742, Uncharacterized conserved protein Function unknown 77461597 Common - Protein of unknown function DUF833 Pfl_5376 49 COG3332 COG3332, Uncharacterized conserved protein Function unknown 77458472 Common - ABC transporter, transmembrane region Pfl_2245 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 77456330 Common - Transcriptional Regulator, LysR family Pfl_0102 151 COG0583 LysR, Transcriptional regulator Transcription 77457101 Common - TonB-dependent siderophore receptor Pfl_0874 122 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 77458912 Common - hypothetical protein Pfl_2687 1 None None None 77458398 Common - Glutathione-dependent formaldehyde-activating, GFA Pfl_2171 61 COG3791 COG3791, Uncharacterized conserved protein Function unknown 77456624 Common hslU ATP-dependent protease ATP-binding subunit Pfl_0396 215 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 77459532 Common - putative monovalent cation/H+ antiporter subunit A Pfl_3310 209 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 77459403 Nonpathogen - hypothetical protein Pfl_3181 1 None None None 77458335 Common - Molybdopterin dehydrogenase, FAD-binding Pfl_2108 64 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 77457913 Common - ABC transporter, periplasmic substrate-binding protein Pfl_1686 49 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 77458445 Common glcE glycolate oxidase FAD binding subunit Pfl_2218 158 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 77459979 Common - Nucleoside-specific channel-forming protein, Tsx Pfl_3757 18 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 77456732 Common - Protein of unknown function DUF330 Pfl_0504 14 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 77457849 Common - lipoprotein, putative Pfl_1622 1 None None None 77460789 Common - hypothetical protein Pfl_4568 9 None None None 77460608 Common - ornithine carbamoyltransferase Pfl_4387 239 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 77461070 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Pfl_4849 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 77457748 Common - Acylneuraminate cytidylyltransferase Pfl_1521 98 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 77460991 Common - Heat shock protein DnaJ-like Pfl_4770 9 COG2214 CbpA, DnaJ-class molecular chaperone Posttranslational modification, protein turnover, chaperones 77456773 Common - hypothetical protein Pfl_0545 113 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 77461324 Common - hypothetical protein Pfl_5103 97 COG1981 COG1981, Predicted membrane protein Function unknown 77456421 Common - hypothetical protein Pfl_0193 2 COG5583 COG5583, Uncharacterized small protein Function unknown 77456583 Common - lipoprotein, putative Pfl_0355 7 None None None 77461744 Common - Transcriptional Regulator, XRE family with Cupin sensor domain Pfl_5523 95 COG1396 HipB, Predicted transcriptional regulators Transcription 77458486 Common - Transcriptional Regulator, AraC family Pfl_2259 83 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77460885 Common - Heavy Metal Sensor Signal Transduction Histidine Kinases (STHK) Pfl_4664 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77459279 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pfl_3057 89 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 77457426 Common - Methylated-DNA-(protein)-cysteine S-methyltransferase Pfl_1199 47 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 77456948 Common - NAD-dependent epimerase/dehydratase Pfl_0720 61 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77457963 Common - Protein of unknown function DUF403 Pfl_1736 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 77457095 Common - BolA-like protein Pfl_0868 43 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 77456459 Common - Secretion protein HlyD Pfl_0231 113 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77456724 Common - Protein of unknown function DUF1249 Pfl_0496 28 COG3151 COG3151, Uncharacterized protein conserved in bacteria Function unknown 77458173 Common - hypothetical protein Pfl_1946 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 77458231 Common - Two Component, Sigma-54 Specific, Transcriptional Regulator, Fis family Pfl_2004 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77458989 Nonpathogen - hypothetical protein Pfl_2764 1 None None None 77456833 Common cobH precorrin-8X methylmutase Pfl_0605 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 77457782 Common - hypothetical protein Pfl_1555 12 None None None 77457034 Common prfC peptide chain release factor 3 Pfl_0807 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 77456339 Common - Acetyl-CoA hydrolase Pfl_0111 95 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 77459290 Common - GCN5-related N-acetyltransferase Pfl_3068 10 None None None 77457137 Common - homogentisate 1,2-dioxygenase Pfl_0910 38 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 77457447 Common - OmpA/MotB Pfl_1220 164 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77457131 Common - S-type Pyocin Pfl_0904 8 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 77461382 Common - pyrroloquinoline quinone biosynthesis protein PqqE Pfl_5161 168 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 77456332 Common trpA tryptophan synthase subunit alpha Pfl_0104 216 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 77460833 Common iscS cysteine desulfurase Pfl_4612 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 77458385 Common - Methylated-DNA-(protein)-cysteine S-methyltransferase Pfl_2158 214 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 77460751 Common - hypothetical protein Pfl_4530 127 COG2606 EbsC, Uncharacterized conserved protein Function unknown 77459981 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_3759 157 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77456646 Common - hypothetical protein Pfl_0418 14 None None None 77458547 Common - Transcriptional Regulator, AraC family Pfl_2320 91 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77459132 Common - chemotaxis sensory transducer Pfl_2907 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77460929 Common - Protein of unknown function DUF1302 Pfl_4708 18 None None None 77458940 Common - Short-chain dehydrogenase/reductase SDR Pfl_2715 161 COG3967 DltE, Short-chain dehydrogenase involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 77461614 Common - hypothetical protein Pfl_5393 55 COG2267 PldB, Lysophospholipase Lipid metabolism 77456966 Common - hypothetical protein Pfl_0739 44 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 77457860 Common - phosphoribosylaminoimidazole synthetase Pfl_1633 231 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 77461936 Common - Sigma-24 (FecI) Pfl_5719 8 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77457408 Common - DTW Pfl_1181 31 COG3148 COG3148, Uncharacterized conserved protein Function unknown 77460835 Common - Serine O-acetyltransferase Pfl_4614 194 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 77456568 Common - Signal transduction histidine kinase, nitrogen specific, NtrB Pfl_0340 220 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 77460320 Common - Leucine-rich repeat Pfl_4099 21 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 77459147 Common - hypothetical protein Pfl_2922 1 None None None 77461523 Common - Malonate decarboxylase, alpha subunit Pfl_5302 27 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 77457789 Common - Cobyrinic acid a,c-diamide synthase Pfl_1562 167 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77459093 Common - Thiolase Pfl_2868 173 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77457822 Common - Hydroxypyruvate reductase Pfl_1595 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 77459876 Common - hydroxymethylglutaryl-CoA lyase Pfl_3654 96 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 77457086 Common - OstA-like protein Pfl_0859 54 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 77461241 Common - hypothetical protein Pfl_5020 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 77461589 Common - Binding-protein-dependent transport systems inner membrane component Pfl_5368 135 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 77460881 Nonpathogen - hypothetical protein Pfl_4660 1 None None None 77456807 Common - Histidine Kinase Pfl_0579 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77459057 Common - Protein of unknown function DUF330 Pfl_2832 16 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 77459164 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_2939 166 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77458202 Common - hypothetical protein Pfl_1975 4 None None None 77456804 Common - heat shock protein YegD Pfl_0576 233 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 77457801 Common - hypothetical protein Pfl_1574 21 COG5184 ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins Cell division and chromosome partitioning / Cytoskeleton 77459562 Common - universal stress protein family Pfl_3340 38 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 77456922 Common - Transcriptional Regulator, LysR family Pfl_0694 114 COG0583 LysR, Transcriptional regulator Transcription 77458682 Common - ThiJ/PfpI Pfl_2457 109 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77460587 Common - Carbohydrate-selective porin OprB Pfl_4366 18 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 77461775 Common - NAD-dependent epimerase/dehydratase Pfl_5554 77 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77458134 Common - Cytochrome c, class I Pfl_1907 57 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 77456632 Common - Penicillin-binding protein 1A Pfl_0404 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 77461413 Common - Glutathione S-transferase-like Pfl_5192 67 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77456606 Common - chemotaxis sensory transducer Pfl_0378 142 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77458613 Common - Alpha/beta hydrolase fold Pfl_2386 85 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77458996 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pfl_2771 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 77459337 Common - Phosphoglycerate/bisphosphoglycerate mutase Pfl_3115 29 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 77461023 Common - sugar fermentation stimulation protein A Pfl_4802 109 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 77457783 Common - hypothetical protein Pfl_1556 27 COG5184 ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins Cell division and chromosome partitioning / Cytoskeleton 77458180 Common - hypothetical protein Pfl_1953 25 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77456796 Common - regulatory protein, LysR Pfl_0568 143 COG0583 LysR, Transcriptional regulator Transcription 77460243 Common - chemotaxis sensory transducer Pfl_4022 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77461153 Common - putative aminotransferase Pfl_4932 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 77456377 Common - Lipase, class 3 Pfl_0149 15 COG3675 COG3675, Predicted lipase Lipid metabolism 77458108 Common - Thioesterase superfamily Pfl_1881 34 COG0824 FcbC, Predicted thioesterase General function prediction only 77460288 Common - Glycosyl transferase Pfl_4067 186 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77459248 Common - Protein of unknown function DUF1527 Pfl_3026 22 None None None 77456821 Common - ABC transporter-like Pfl_0593 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 77459009 Common - transporter, putative Pfl_2784 16 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 77456592 Common - ABC transporter-like Pfl_0364 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 77460879 Common - chemotaxis sensory transducer, Pas/Pac sensor Pfl_4658 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77461801 Common - lipoprotein, putative Pfl_5580 33 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 77460580 Common - Aminotransferase, class V Pfl_4359 230 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 77460230 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Pfl_4009 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 77457452 Common dinG ATP-dependent DNA helicase DinG Pfl_1225 130 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 77460854 Common - hypothetical protein Pfl_4633 22 None None None 77456268 Common - lipoprotein, putative Pfl_0040 20 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 77456563 Common - Glutaredoxin, GrxC Pfl_0335 122 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 77459631 Common - Protein of unknown function DUF1316 Pfl_3409 3 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 77460122 Common - General substrate transporter Pfl_3901 143 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 77457430 Common - hypothetical protein Pfl_1203 1 None None None 77458508 Common - Transcriptional Regulator, LysR family Pfl_2281 182 COG0583 LysR, Transcriptional regulator Transcription 77460935 Common - Peptidase M48, Ste24p Pfl_4714 124 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 77457622 Common - tRNA/rRNA methyltransferase (SpoU) Pfl_1395 23 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 77457440 Common - Peptidase S45, penicillin amidase Pfl_1213 76 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 77457437 Common - extracellular solute-binding protein, family 3 Pfl_1210 174 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77458460 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pfl_2233 157 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 77460172 Common - Exonuclease Pfl_3951 18 COG5018 KapD, Inhibitor of the KinA pathway to sporulation, predicted exonuclease General function prediction only 77459304 Common - Pilus retraction protein PilT Pfl_3082 207 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 77457280 Common - CheW protein Pfl_1053 43 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77457899 Common - Protein of unknown function DUF1232 Pfl_1672 16 COG3339 COG3339, Uncharacterized conserved protein Function unknown 77458458 Common - Transcriptional Regulator, TetR family Pfl_2231 98 COG1309 AcrR, Transcriptional regulator Transcription 77459537 Common - putative monovalent cation/H+ antiporter subunit G Pfl_3315 44 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 77457119 Common - short chain dehydrogenase Pfl_0892 219 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77459165 Common - 2-nitropropane dioxygenase, NPD Pfl_2940 117 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 77460099 Common fadA 3-ketoacyl-CoA thiolase Pfl_3878 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77461885 Common cls cardiolipin synthetase Pfl_5665 144 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 77460001 Common - N-isopropylammelide isopropylaminohydrolase Pfl_3779 71 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 77458950 Common - Transcriptional Regulator, LysR family Pfl_2725 159 COG0583 LysR, Transcriptional regulator Transcription 77458715 Common - Protein of unknown function DUF6, transmembrane Pfl_2490 63 COG2962 RarD, Predicted permeases General function prediction only 77460529 Common - chemotaxis sensory transducer, Pas/Pac sensor Pfl_4308 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77461629 Common - Glutamate--ammonia ligase Pfl_5408 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 77458687 Common - TonB-dependent siderophore receptor Pfl_2462 107 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 77457471 Common - ABC transporter-like Pfl_1244 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 77457714 Common - PHP-like Pfl_1487 118 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 77460740 Common - dihydroorotase Pfl_4519 88 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 77460920 Common - tryptophanyl-tRNA synthetase Pfl_4699 219 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77460995 Common - hypothetical protein Pfl_4774 1 None None None 77458978 Common - Short-chain dehydrogenase/reductase SDR Pfl_2753 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77457931 Common - allantoicase Pfl_1704 15 COG4266 Alc, Allantoicase Nucleotide transport and metabolism 77456586 Common - Transcriptional Regulator, Histidine utilization repressor, GntR family Pfl_0358 127 COG2188 PhnF, Transcriptional regulators Transcription 77457833 Common - Substrate-binding region of ABC-type glycine betaine transport system Pfl_1606 67 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 77458975 Common - Protein of unknown function DUF1302 Pfl_2750 18 None None None 77460701 Nonpathogen - hypothetical protein Pfl_4480 9 None None None 77456445 Nonpathogen - hypothetical protein Pfl_0217 1 None None None 77456817 Common - inner-membrane translocator Pfl_0589 103 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 77459736 Common - FAD dependent oxidoreductase Pfl_3514 163 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77457504 Common - outer membrane porin Pfl_1277 9 None None None 77457022 Common - PTS fructose IIC component Pfl_0795 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 77457892 Common - Phospholipid/glycerol acyltransferase Pfl_1665 162 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 77460719 Common - Two component Transcriptional regulator, Winged helix family Pfl_4498 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77459763 Common - Multi antimicrobial extrusion protein MatE Pfl_3541 171 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 77458036 Common - Acyl-CoA dehydrogenase-like Pfl_1809 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77461407 Common - Exonuclease Pfl_5186 79 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 77461328 Common - Histidine triad (HIT) protein Pfl_5107 232 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 77457029 Common - hypothetical protein Pfl_0802 4 None None None 77459809 Common aat leucyl/phenylalanyl-tRNA--protein transferase Pfl_3587 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 77460218 Common - OsmC-like protein Pfl_3997 92 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77460422 Common - hypothetical protein Pfl_4201 8 None None None 77456845 Common prmA ribosomal protein L11 methyltransferase Pfl_0617 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 77457347 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Pfl_1120 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 77456390 Common - Adenylylsulfate kinase Pfl_0162 143 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 77461956 Common - Cobyrinic acid a,c-diamide synthase Pfl_5739 228 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77458575 Nonpathogen - hypothetical protein Pfl_2348 1 None None None 77461129 Common - Protein of unknown function DUF6, transmembrane Pfl_4908 151 COG2962 RarD, Predicted permeases General function prediction only 77457115 Common - type III effector HopPmaJ(Pto) Pfl_0888 15 None None None 77458693 Common - Short-chain dehydrogenase/reductase SDR Pfl_2468 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77459812 Common - ATP-dependent clp protease, ATP-binding subunit ClpA Pfl_3590 226 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 77460496 Common alaS alanyl-tRNA synthetase Pfl_4275 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77457322 Common - Na+/H+ antiporter Pfl_1095 97 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 77456501 Nonpathogen - hypothetical protein Pfl_0273 1 None None None 77459892 Common - type 1 pili usher pathway chaperone CsuC Pfl_3670 29 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 77460067 Common - hypothetical protein Pfl_3846 3 None None None 77460117 Common - allantoate amidohydrolase Pfl_3896 86 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 77457608 Common - GtrA-like protein Pfl_1381 7 COG2246 COG2246, Predicted membrane protein Function unknown 77457694 Common - YgfB and YecA Pfl_1467 18 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 77459903 Common - Transcriptional Regulator, LysR family Pfl_3681 192 COG0583 LysR, Transcriptional regulator Transcription 77456508 Common - Formate dehydrogenase, subunit FdhD Pfl_0280 135 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 77459423 Common - Alkylhydroperoxidase AhpD core Pfl_3201 83 COG2128 COG2128, Uncharacterized conserved protein Function unknown 77458194 Common - Isochorismatase hydrolase Pfl_1967 75 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 77461673 Common - ChaC-like protein Pfl_5452 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 77461122 Common - Transcriptional Regulator, LysR family Pfl_4901 160 COG0583 LysR, Transcriptional regulator Transcription 77461066 Common - type IV pilus assembly protein PilW Pfl_4845 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 77457521 Common - Transcriptional Regulator, IclR family Pfl_1294 65 COG1414 IclR, Transcriptional regulator Transcription 77458734 Nonpathogen - hypothetical protein Pfl_2509 1 None None None 77459648 Common - Ferredoxin Pfl_3426 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 77456763 Common rpsR 30S ribosomal protein S18 Pfl_0535 213 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 77459913 Common - Transcriptional Regulator, LysR family Pfl_3691 170 COG0583 LysR, Transcriptional regulator Transcription 77461627 Common - putative aminotransferase Pfl_5406 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 77456989 Common - GrpE protein Pfl_0762 224 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 77459571 Common - hypothetical protein Pfl_3349 15 None None None 77457815 Common - hypothetical protein Pfl_1588 33 COG1598 COG1598, Uncharacterized conserved protein Function unknown 77461264 Common - hypothetical protein Pfl_5043 12 COG3789 COG3789, Uncharacterized protein conserved in bacteria Function unknown 77461373 Common - Histidine triad (HIT) protein Pfl_5152 36 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 77457279 Common - chemotaxis sensory transducer Pfl_1052 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77461632 Common ssuB aliphatic sulfonates transport ATP-binding subunit Pfl_5411 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 77461088 Nonpathogen - hypothetical protein Pfl_4867 2 None None None 77457853 Common - Dienelactone hydrolase Pfl_1626 95 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 77459297 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3075 219 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 77458993 Common - Transcriptional Regulator, MarR family Pfl_2768 98 COG1846 MarR, Transcriptional regulators Transcription 77461272 Common uvrA excinuclease ABC subunit A Pfl_5051 244 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 77459486 Common - Predicted transcriptional regulator Pfl_3264 108 COG1733 COG1733, Predicted transcriptional regulators Transcription 77456904 Common - short chain dehydrogenase Pfl_0676 202 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77460359 Common - Transcriptional Regulator, GntR family Pfl_4138 79 COG2188 PhnF, Transcriptional regulators Transcription 77460631 Common - hypothetical protein Pfl_4410 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 77459743 Common - hypothetical protein Pfl_3521 29 None None None 77459757 Common - Transcriptional Regulator, TetR family Pfl_3535 13 COG1309 AcrR, Transcriptional regulator Transcription 77457777 Common fliQ flagellar biosynthesis protein FliQ Pfl_1550 94 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 77460737 Nonpathogen - hypothetical protein Pfl_4516 2 None None None 77457163 Common - 2-hydroxyacid dehydrogenase Pfl_0936 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 77459195 Common - chemotaxis sensory transducer Pfl_2970 125 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77456571 Common - hypothetical protein Pfl_0343 11 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 77457704 Common - membrane protein-like Pfl_1477 21 COG4323 COG4323, Predicted membrane protein Function unknown 77461752 Common - Aminotransferase, class I and II Pfl_5531 232 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 77457419 Common - K+ potassium transporter Pfl_1192 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 77458957 Common - pyruvate decarboxylase Pfl_2732 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 77458221 Nonpathogen - hypothetical protein Pfl_1994 1 None None None 77461204 Common - hypothetical protein Pfl_4983 35 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 77457647 Common - ATP-dependent helicase HrpA Pfl_1420 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 77460365 Common - regulatory protein GntR, HTH Pfl_4144 124 COG2186 FadR, Transcriptional regulators Transcription 77458176 Common - hypothetical protein Pfl_1949 1 None None None 77456975 Nonpathogen - hypothetical protein Pfl_0748 1 None None None 77461250 Common - OmpW Pfl_5029 69 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 77457413 Common - hypothetical protein Pfl_1186 96 COG1720 COG1720, Uncharacterized conserved protein Function unknown 77458556 Common - Rhs element Vgr protein Pfl_2329 57 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 77461835 Common - Binding-protein-dependent transport systems inner membrane component Pfl_5614 214 COG4590 COG4590, ABC-type uncharacterized transport system, permease component General function prediction only 77460191 Common - hypothetical protein Pfl_3970 3 COG5393 COG5393, Predicted membrane protein Function unknown 77456666 Common - acyl carrier protein Pfl_0438 42 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77458079 Common - Twin-arginine translocation pathway signal Pfl_1852 159 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 77458676 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pfl_2451 183 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 77461034 Common pgi glucose-6-phosphate isomerase Pfl_4813 189 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 77459601 Common - Two component Heavy metal response Transcriptional regulator, Winged helix family Pfl_3379 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77458526 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_2299 192 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77456487 Common - RNA binding S1 Pfl_0259 173 COG2183 Tex, Transcriptional accessory protein Transcription 77459218 Common - hypothetical protein Pfl_2996 24 None None None 77461595 Common - prolipoprotein diacylglyceryl transferase Pfl_5374 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 77457803 Common - hypothetical protein Pfl_1576 7 None None None 77456855 Common - arginine decarboxylase Pfl_0627 79 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 77459590 Common - DNA-binding transcriptional regulator CynR Pfl_3368 191 COG0583 LysR, Transcriptional regulator Transcription 77456405 Common - predicted outer membrane protein Pfl_0177 27 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 77457212 Common - putative SAM-dependent methyltransferase Pfl_0985 29 COG3129 COG3129, Predicted SAM-dependent methyltransferase General function prediction only 77459233 Common - hypothetical protein Pfl_3011 22 None None None 77456357 Common - Transcriptional Regulator, GntR family Pfl_0129 131 COG1802 GntR, Transcriptional regulators Transcription 77457017 Nonpathogen - hypothetical protein Pfl_0790 1 None None None 77458824 Common - hypothetical protein Pfl_2599 13 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 77458041 Common - hypothetical protein Pfl_1814 52 COG2836 COG2836, Uncharacterized conserved protein Function unknown 77459686 Common - Transketolase-like Pfl_3464 167 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 77458919 Common - Protein of unknown function DUF1282 Pfl_2694 19 None None None 77460691 Common - Betaine-aldehyde dehydrogenase Pfl_4470 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77456750 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase Pfl_0522 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 77457337 Common - Outer membrane chaperone Skp Pfl_1110 59 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 77460865 Common - protoheme IX farnesyltransferase Pfl_4644 187 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 77460616 Common - Cold-shock DNA-binding protein Pfl_4395 176 COG1278 CspC, Cold shock proteins Transcription 77457410 Common - diacylglycerol kinase Pfl_1183 67 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 77459430 Common - ATPase associated with various cellular activities, AAA_3 Pfl_3208 180 COG0714 COG0714, MoxR-like ATPases General function prediction only 77459576 Common - Two component Transcriptional regulator, Winged helix family Pfl_3354 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77456759 Common - extracellular solute-binding protein, family 1 Pfl_0531 120 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 77460602 Common - Protein of unknown function DUF454 Pfl_4381 84 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 77456757 Common - chemotaxis sensory transducer Pfl_0529 143 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77459615 Common - UspA Pfl_3393 40 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 77460385 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Pfl_4164 170 COG0546 Gph, Predicted phosphatases General function prediction only 77460967 Common - molybdopterin biosynthesis protein MoeB Pfl_4746 201 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 77460724 Common fxsA FxsA Pfl_4503 19 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 77461296 Common rpsS 30S ribosomal protein S19 Pfl_5075 246 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 77458608 Common - Protein of unknown function DUF72 Pfl_2381 86 COG1801 COG1801, Uncharacterized conserved protein Function unknown 77458314 Common - hypothetical protein Pfl_2087 1 None None None 77458395 Common - NnrS Pfl_2168 51 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 77461693 Common - hypothetical protein Pfl_5472 27 COG3014 COG3014, Uncharacterized protein conserved in bacteria Function unknown 77460773 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with Response Regulator Receiver modulation Pfl_4552 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77461313 Common secE preprotein translocase subunit SecE Pfl_5092 29 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 77461344 Common - Binding-protein-dependent transport systems inner membrane component Pfl_5123 152 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 77456701 Common - Carbamoyltransferase Pfl_0473 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 77459724 Common - hypothetical protein Pfl_3502 3 None None None 77457966 Common - acetyl-CoA acetyltransferase Pfl_1739 170 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77461909 Common - Pyridoxamine 5'-phosphate oxidase-like, FMN-binding Pfl_5689 128 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 77461147 Common - Predicted periplasmic ligand-binding sensor protein Pfl_4926 30 COG3416 COG3416, Uncharacterized protein conserved in bacteria Function unknown 77459977 Common - selenophosphate synthetase Pfl_3755 116 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 77458498 Common - hypothetical protein Pfl_2271 1 None None None 77459134 Common - Transcriptional Regulator, CdaR Pfl_2909 47 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 77459927 Common - Integral membrane protein TerC Pfl_3705 115 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 77461045 Common - zinc-binding protein Pfl_4824 66 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 77460848 Common - HNH endonuclease Pfl_4627 6 None None None 77457374 Common - hypothetical protein Pfl_1147 2 None None None 77460655 Common - hypothetical protein Pfl_4434 30 COG0392 COG0392, Predicted integral membrane protein Function unknown 77457098 Common hisD histidinol dehydrogenase Pfl_0871 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 77458410 Common - Lytic transglycosylase, catalytic Pfl_2183 140 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 77459748 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Pfl_3526 206 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 77456238 Common glyQ glycyl-tRNA synthetase subunit alpha Pfl_0010 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 77461558 Common - Cell division transporter substrate-binding protein FtsY Pfl_5337 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 77457653 Common - aquaporin Z Pfl_1426 130 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 77461004 Common - putative sulfite oxidase subunit YedZ Pfl_4783 69 COG2717 COG2717, Predicted membrane protein Function unknown 77456452 Nonpathogen - hypothetical protein Pfl_0224 1 None None None 77458340 Common - hypothetical protein Pfl_2113 2 None None None 77456279 Common - Endonuclease/exonuclease/phosphatase Pfl_0051 37 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 77459160 Common - hypothetical protein Pfl_2935 1 None None None 77457329 Common tsf elongation factor Ts Pfl_1102 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 77459481 Common - Integral membrane protein TerC Pfl_3259 98 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 77457758 Common - hypothetical protein Pfl_1531 1 None None None 77461511 Common - D-amino-acid dehydrogenase Pfl_5290 111 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77461702 Common - Peptidylprolyl isomerase, FKBP-type Pfl_5481 126 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 77458932 Common - Translation elongation factor, selenocysteine-specific Pfl_2707 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 77456613 Common - 2-polyprenylphenol 6-hydroxylase Pfl_0385 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 77457051 Nonpathogen - hypothetical protein Pfl_0824 1 None None None 77459678 Common - TRAP dicarboxylate transporter, DctM subunit Pfl_3456 136 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 77460008 Common - Sigma-24 (FecI) Pfl_3786 113 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77458023 Common - Xanthine dehydrogenase Pfl_1796 108 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 77457959 Common - spermidine synthase Pfl_1732 132 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 77457751 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III, putative Pfl_1524 200 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 77457262 Common - RecJ exonuclease Pfl_1035 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 77457737 Common - Nucleotidyl transferase Pfl_1510 172 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 77456231 Common recF recombination protein F Pfl_0003 166 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 77461567 Common - Twin-arginine translocation pathway signal Pfl_5346 9 None None None 77460636 Common - Cold-shock DNA-binding protein Pfl_4415 176 COG1278 CspC, Cold shock proteins Transcription 77459528 Nonpathogen - hypothetical protein Pfl_3306 1 None None None 77456281 Common - Cytochrome c, class I Pfl_0053 60 COG2863 COG2863, Cytochrome c553 Energy production and conversion 77460239 Common - hypothetical protein Pfl_4018 1 None None None 77458072 Common - peptide synthase Pfl_1845 221 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77458491 Nonpathogen - hypothetical protein Pfl_2264 1 None None None 77458207 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pfl_1980 150 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 77458187 Common - Transcriptional Regulator, AraC family Pfl_1960 119 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77457393 Common - hypothetical protein Pfl_1166 7 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 77460393 Common - Protein tyrosine phosphatase Pfl_4172 143 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 77457170 Common - Major facilitator superfamily MFS_1 Pfl_0943 174 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77460694 Common - NAD-dependent epimerase/dehydratase Pfl_4473 64 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 77460371 Common - Type IV pilus assembly PilZ Pfl_4150 33 COG3215 PilZ, Tfp pilus assembly protein PilZ Cell motility and secretion / Intracellular trafficking and secretion 77457982 Common - Asp/Glu racemase Pfl_1755 42 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 77457422 Common - DNA polymerase IV Pfl_1195 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 77460225 Common - UspA Pfl_4004 27 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 77456365 Common - Taurine catabolism dioxygenase TauD/TfdA Pfl_0137 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 77457798 Common - CheW protein Pfl_1571 14 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77456775 Common nadE NAD synthetase Pfl_0547 203 COG0171 NadE, NAD synthase Coenzyme metabolism 77458062 Common - ThiJ/PfpI Pfl_1835 143 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77461645 Common - type II secretion system protein E Pfl_5424 180 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 77459554 Nonpathogen - hypothetical protein Pfl_3332 1 None None None 77461648 Common gcvH glycine cleavage system protein H Pfl_5427 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 77458226 Common - hypothetical protein Pfl_1999 2 None None None 77461518 Common - phosphoribosyl-dephospho-CoA transferase Pfl_5297 16 None None None 77456693 Common - Lipopolysaccharide heptosyltransferase II Pfl_0465 111 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 77460624 Common - TonB-like Pfl_4403 8 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 77460554 Common - Lysine exporter protein (LYSE/YGGA) Pfl_4333 34 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77460648 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Pfl_4427 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 77457010 Common - polynucleotide phosphorylase/polyadenylase Pfl_0783 245 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 77461471 Common - Intergral membrane protein Pfl_5250 52 COG1289 COG1289, Predicted membrane protein Function unknown 77459063 Common - Binding-protein-dependent transport systems inner membrane component Pfl_2838 112 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 77457843 Common - dihydrolipoamide dehydrogenase Pfl_1616 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 77461901 Common - NAD-dependent epimerase/dehydratase Pfl_5681 226 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77459346 Common - TonB-dependent receptor Pfl_3124 108 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 77459515 Common - ABC transporter, substrate-binding protein, aliphatic sulphonates Pfl_3293 68 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 77458796 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pfl_2571 113 COG0388 COG0388, Predicted amidohydrolase General function prediction only 77458139 Common - Carbon storage regulator, CsrA Pfl_1912 82 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 77459796 Common - Protein of unknown function DUF1275 Pfl_3574 13 COG3619 COG3619, Predicted membrane protein Function unknown 77461943 Common - D-fructose-6-phosphate amidotransferase Pfl_5726 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 77458770 Common - hypothetical protein Pfl_2545 1 None None None 77461209 Common - Sigma-54 Specific Transcriptional Regulator containing GAF, and Fis DNA-binding domains Pfl_4988 176 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 77457292 Common - hypothetical protein Pfl_1065 2 None None None 77460090 Common - 5'-methylthioadenosine phosphorylase Pfl_3869 165 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 77457181 Common - alginate biosynthesis protein AlgX Pfl_0954 5 None None None 77458402 Common - hypothetical protein Pfl_2175 13 None None None 77456867 Common - Peptidase A24A, prepilin type IV Pfl_0639 1 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 77456890 Common - hypothetical protein Pfl_0662 1 None None None 77460052 Common - Protein of unknown function DUF940 Pfl_3830 22 None None None 77461289 Common rplX 50S ribosomal protein L24 Pfl_5068 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 77461486 Common pgk phosphoglycerate kinase Pfl_5265 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 77458537 Common - Transcriptional Regulator, AraC family Pfl_2310 142 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77460343 Common - D-galactonate transporter Pfl_4122 207 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77459415 Common - hypothetical protein Pfl_3193 11 None None None 77461603 Common - ribose-5-phosphate isomerase A Pfl_5382 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 77459437 Nonpathogen - hypothetical protein Pfl_3215 1 None None None 77459868 Common - Protein of unknown function DUF490 Pfl_3646 102 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 77460462 Common - outer membrane protein H1 Pfl_4241 4 None None None 77457883 Common - hypothetical protein Pfl_1656 3 None None None 77461356 Common ksgA dimethyladenosine transferase Pfl_5135 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 77458984 Common - transcriptional regulator NfxB Pfl_2759 9 None None None 77456416 Common - 4-aminobutyrate aminotransferase Pfl_0188 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 77456542 Nonpathogen - hypothetical protein Pfl_0314 1 None None None 77456525 Common - GCN5-related N-acetyltransferase Pfl_0297 20 COG0456 RimI, Acetyltransferases General function prediction only 77459222 Common - single-strand DNA-binding protein Pfl_3000 19 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 77460491 Common - Arc-like DNA binding Pfl_4270 9 None None None 77456554 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Pfl_0326 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 77457925 Common - hypothetical protein Pfl_1698 16 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 77459300 Common - hypothetical protein Pfl_3078 35 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 77458258 Common - ISPsy11, transposase OrfA Pfl_2031 9 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 77458118 Common - UbiE/COQ5 methyltransferase Pfl_1891 213 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77460514 Common acsA acetyl-CoA synthetase Pfl_4293 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 77459025 Common - hypothetical protein Pfl_2800 75 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 77457551 Common - hypothetical protein Pfl_1324 24 COG3652 COG3652, Predicted outer membrane protein Function unknown 77460156 Common - Two component Transcriptional regulator, Winged helix family Pfl_3935 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77458430 Common - Sulfatase Pfl_2203 54 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 77457369 Common - Phage tail protein I Pfl_1142 24 COG4385 gpI, Bacteriophage P2-related tail formation protein General function prediction only 77461869 Common - Thioesterase superfamily Pfl_5649 135 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 77460791 Common - hypothetical protein Pfl_4570 10 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 77459323 Common - Cobalt transporter subunit CbtA, putative Pfl_3101 16 COG5446 COG5446, Predicted integral membrane protein Function unknown 77457573 Common - ISPsy11, transposase OrfA Pfl_1346 9 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 77458515 Nonpathogen - hypothetical protein Pfl_2288 1 None None None 77459856 Common - ABC transporter-like Pfl_3634 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 77459031 Common - Carboxymuconolactone decarboxylase Pfl_2806 80 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 77458245 Nonpathogen - O-antigen polymerase Pfl_2018 8 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 77457204 Common - regulatory protein GntR, HTH Pfl_0977 146 COG2186 FadR, Transcriptional regulators Transcription 77456496 Common - phosphoenolpyruvate carboxykinase Pfl_0268 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 77461306 Common - DNA-directed RNA polymerase subunit beta' Pfl_5085 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 77457350 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Pfl_1123 190 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 77457488 Common - hypothetical protein Pfl_1261 1 None None None 77456650 Common - 3-oxoacyl-(acyl carrier protein) synthase II Pfl_0422 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77457196 Common - FAD dependent oxidoreductase Pfl_0969 75 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77461582 Common - Dihydrofolate reductase Pfl_5361 143 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 77458849 Nonpathogen - hypothetical protein Pfl_2624 1 None None None 77459802 Common - Fructose-bisphosphate aldolase Pfl_3580 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77461855 Common - GCN5-related N-acetyltransferase Pfl_5635 75 COG0456 RimI, Acetyltransferases General function prediction only 77461840 Common - hypothetical protein Pfl_5619 18 COG3495 COG3495, Uncharacterized protein conserved in bacteria Function unknown 77458531 Common - Transcriptional Regulator, AraC family Pfl_2304 100 COG1609 PurR, Transcriptional regulators Transcription 77457128 Common - hypothetical protein Pfl_0901 70 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 77461166 Common - phosphomethylpyrimidine kinase Pfl_4945 221 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 77458803 Common - hypothetical protein Pfl_2578 22 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 77460936 Common - chemotaxis sensory transducer Pfl_4715 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77458266 Common - ribonuclease inhibitor barstar Pfl_2039 5 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 77458477 Common - Response regulator receiver domain protein (CheY) Pfl_2250 142 COG4566 TtrR, Response regulator Signal transduction mechanisms 77461055 Common - Chaperone clpB Pfl_4834 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 77461215 Common - DedA Pfl_4994 147 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 77460437 Common mazG nucleoside triphosphate pyrophosphohydrolase Pfl_4216 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 77457462 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Pfl_1235 212 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 77457670 Common - lipoprotein, putative Pfl_1443 14 None None None 77461188 Common - Rare lipoprotein A Pfl_4967 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 77458437 Common - Transcriptional Regulator, LuxR family Pfl_2210 2 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77457301 Common - carboxyvinyl-carboxyphosphonate phosphorylmutase, putative Pfl_1074 101 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 77458516 Common - hypothetical protein Pfl_2289 3 None None None 77460306 Common - hypothetical protein Pfl_4085 6 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 77460164 Common - periplasmic binding protein Pfl_3943 7 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77461016 Common - TfoX-like Pfl_4795 11 COG3070 TfoX, Regulator of competence-specific genes Transcription 77456695 Common - Glycosyl transferase, group 1 Pfl_0467 138 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77456933 Common - putative oxidoreductase, MmfH Pfl_0705 57 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77459034 Common - Deoxyribodipyrimidine photolyase-like protein Pfl_2809 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 77458275 Common - Flavin-containing monooxygenase FMO Pfl_2048 74 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 77461159 Common - hypothetical protein Pfl_4938 6 None None None 77459396 Common - type II secretion system protein E Pfl_3174 212 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 77457839 Common sdhA succinate dehydrogenase flavoprotein subunit Pfl_1612 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 77457482 Common - ATP-dependent helicase HepA Pfl_1255 117 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 77461040 Common - general secretion pathway protein H Pfl_4819 11 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 77456389 Common - Outer membrane efflux protein Pfl_0161 38 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77461605 Common - SdiA-regulated Pfl_5384 9 COG3204 COG3204, Uncharacterized protein conserved in bacteria Function unknown 77460311 Common - hypothetical protein Pfl_4090 108 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 77459583 Common - Protein of unknown function DUF427 Pfl_3361 53 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 77460420 Common - Predicted signal transduction protein containing EFhand domain Pfl_4199 2 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 77458736 Common - hypothetical protein Pfl_2511 1 None None None 77456245 Common def peptide deformylase Pfl_0017 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 77460169 Common - Acyl-CoA dehydrogenase-like Pfl_3948 162 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77460170 Common - Enoyl-CoA hydratase/isomerase Pfl_3949 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77458582 Common - hypothetical protein Pfl_2355 3 None None None 77459173 Nonpathogen - hypothetical protein Pfl_2948 1 None None None 77460766 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Pfl_4545 142 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 77460264 Common - Glycosyl transferase, family 2 Pfl_4043 118 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77457881 Common - Glutathione peroxidase Pfl_1654 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 77461638 Common - outer membrane porin Pfl_5417 9 None None None 77460485 Common - Twin-arginine translocation pathway signal Pfl_4264 9 None None None 77461716 Common - Protein of unknown function DUF1289 Pfl_5495 7 COG3313 COG3313, Predicted Fe-S protein General function prediction only 77459014 Common - CinA-like Pfl_2789 192 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 77457712 Common - YciI-like protein Pfl_1485 71 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 161485590 Common - cell developmental protein SirA Pfl_3888 98 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77459060 Common arnT 4-amino-4-deoxy-L-arabinose transferase Pfl_2835 72 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 77460516 Common - ribonucleotide-diphosphate reductase subunit beta Pfl_4295 154 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 77457316 Common - Glycosyl transferase, family 2 Pfl_1089 132 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 77458425 Common - Protein of unknown function DUF1315 Pfl_2198 27 COG3139 COG3139, Uncharacterized protein conserved in bacteria Function unknown 77459675 Common - Senescence marker protein-30 (SMP-30) Pfl_3453 82 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 77458897 Common - UvrD/REP helicase Pfl_2672 191 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 77457725 Common phhB pterin-4-alpha-carbinolamine dehydratase Pfl_1498 79 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 77460559 Common - Transcriptional Regulator, LysR family Pfl_4338 149 COG0583 LysR, Transcriptional regulator Transcription 77457531 Common - Protein of unknown function DUF1508 Pfl_1304 25 COG3422 COG3422, Uncharacterized conserved protein Function unknown 77457110 Common - Glutathione peroxidase Pfl_0883 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 77459491 Common - acetylornithine deacetylase Pfl_3269 209 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 77461761 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase Pfl_5540 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 77456533 Common - hypothetical protein Pfl_0305 13 COG1598 COG1598, Uncharacterized conserved protein Function unknown 77458243 Common - Glycosyl transferase, family 2 Pfl_2016 78 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77459496 Common - iron-sulfur cluster-binding protein Pfl_3274 11 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 77459824 Common - isocitrate lyase Pfl_3602 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 77459011 Common - Alpha/beta hydrolase fold Pfl_2786 67 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77457381 Common - Bacteriophage Mu tail sheath Pfl_1154 21 COG4386 COG4386, Mu-like prophage tail sheath protein gpL General function prediction only 77459597 Common - DoxX Pfl_3375 9 COG2259 COG2259, Predicted membrane protein Function unknown 77458570 Common - Amino acid permease-associated region Pfl_2343 163 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 77459730 Common - Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain Pfl_3508 192 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77459505 Common - Mandelate racemase/muconate lactonizing enzyme Pfl_3283 118 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 77457687 Common - Type I secretion membrane fusion protein, HlyD Pfl_1460 137 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77457633 Common - Allophanate hydrolase subunit 1 Pfl_1406 99 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 77461193 Common - hypothetical protein Pfl_4972 182 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 77458302 Common - 3-oxoacid CoA-transferase Pfl_2075 103 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 77456471 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_0243 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77458640 Common - hypothetical protein Pfl_2413 6 COG5455 COG5455, Predicted integral membrane protein Function unknown 77459373 Common - hypothetical protein Pfl_3151 34 COG4544 COG4544, Uncharacterized conserved protein Function unknown 77461304 Common - 30S ribosomal protein S7 Pfl_5083 244 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 77461072 Common lspA lipoprotein signal peptidase Pfl_4851 104 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77458811 Common - 6-phosphogluconate dehydrogenase-like protein Pfl_2586 184 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 77461428 Common - Sarcosine oxidase, beta subunit, heterotetrameric Pfl_5207 124 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77456393 Common - Band 7 protein Pfl_0165 191 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 77460355 Common - hypothetical protein Pfl_4134 20 None None None 77458528 Common - ABC transporter-like Pfl_2301 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 77458544 Common - regulatory protein GntR, HTH Pfl_2317 196 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 77461858 Common - Outer membrane autotransporter barrel Pfl_5638 42 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 77461253 Common - DEAD/DEAH box helicase-like Pfl_5032 223 COG1201 Lhr, Lhr-like helicases General function prediction only 77456380 Common - hypothetical protein Pfl_0152 1 None None None 77458081 Common - Twin-arginine translocation pathway signal Pfl_1854 3 None None None 77457258 Common - hypothetical protein Pfl_1031 1 None None None 77457730 Common flgH flagellar basal body L-ring protein Pfl_1503 101 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 77458554 Common - Catechol 1,2-dioxygenase Pfl_2327 46 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 77457339 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase Pfl_1112 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 77458322 Common - hypothetical protein Pfl_2095 9 None None None 77457040 Common - extracellular solute-binding protein, family 5 Pfl_0813 208 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 77459069 Common - Polysaccharide deacetylase Pfl_2844 20 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 77458364 Nonpathogen - hypothetical protein Pfl_2137 3 COG1289 COG1289, Predicted membrane protein Function unknown 77458234 Common - Predicted transcriptional regulator Pfl_2007 38 COG3636 COG3636, Predicted transcriptional regulator Transcription 77461460 Common - Binding-protein-dependent transport systems inner membrane component Pfl_5239 206 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 77456745 Common - 4Fe-4S cluster binding Pfl_0517 134 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 77457068 Common maf Maf-like protein Pfl_0841 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 77461039 Common - Transport-associated Pfl_4818 33 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 77456327 Common - Protein of unknown function DUF1161 Pfl_0099 5 None None None 77461186 Common - hypothetical protein Pfl_4965 7 COG2921 COG2921, Uncharacterized conserved protein Function unknown 77456301 Common - hypothetical protein Pfl_0073 6 None None None 77456786 Common - Cation efflux protein Pfl_0558 58 COG3965 COG3965, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 77457270 Common - Amino acid permease-associated region Pfl_1043 176 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 77456634 Common - Fimbrial assembly Pfl_0406 39 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 77457421 Common - hypothetical protein Pfl_1194 67 COG2898 COG2898, Uncharacterized conserved protein Function unknown 77461786 Common - Protein of unknown function DUF1311 Pfl_5565 12 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 77459845 Common - Outer membrane efflux protein Pfl_3623 112 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77459354 Common - hypothetical protein Pfl_3132 32 COG3652 COG3652, Predicted outer membrane protein Function unknown 77458799 Common - Transcriptional Regulator, LysR family Pfl_2574 163 COG0583 LysR, Transcriptional regulator Transcription 77459129 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pfl_2904 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 77458837 Common - Aspartyl/Asparaginyl beta-hydroxylase Pfl_2612 37 COG3555 COG3555, Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases Posttranslational modification, protein turnover, chaperones 77460565 Common - Substrate-binding region of ABC-type glycine betaine transport system Pfl_4344 58 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 77458909 Common - Outer membrane autotransporter barrel Pfl_2684 145 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 77461576 Common - hypothetical protein Pfl_5355 57 COG0778 NfnB, Nitroreductase Energy production and conversion 77458175 Common - RNA 3'-terminal-phosphate cyclase Pfl_1948 47 COG0430 RCL1, RNA 3'-terminal phosphate cyclase RNA processing and modification 77459958 Common - Glutathione S-transferase-like Pfl_3736 38 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77461229 Common - TonB-dependent receptor Pfl_5008 130 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 77458290 Common - Rhodanese-like Pfl_2063 52 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 77458126 Common - Folylpolyglutamate synthetase Pfl_1899 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 77458871 Common - Multi-sensor Hybrid Histidine Kinase Pfl_2646 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456688 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC and GAF sensor(s) Pfl_0460 185 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77456242 Common trkA potassium transporter peripheral membrane component Pfl_0014 141 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 77456689 Common - Phosphodiesterase/alkaline phosphatase D-like Pfl_0461 11 COG3540 PhoD, Phosphodiesterase/alkaline phosphatase D Inorganic ion transport and metabolism 77458521 Common - hypothetical protein Pfl_2294 2 None None None 77456916 Common - Exodeoxyribonuclease V, RecC subunit Pfl_0688 67 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 77457172 Common - short chain dehydrogenase Pfl_0945 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77461309 Common rplJ 50S ribosomal protein L10 Pfl_5088 210 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 77460599 Common - Putative FecR Pfl_4378 48 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77459459 Common - NUDIX hydrolase Pfl_3237 139 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 77460618 Common - quinolinate synthetase Pfl_4397 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 77459200 Common - quinohemoprotein amine dehydrogenase, 60 kDa subunit Pfl_2975 5 None None None 77457867 Common - hypothetical protein Pfl_1640 2 None None None 77460460 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_4239 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77460653 Common - Glycosyl transferase, group 1 Pfl_4432 208 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77457525 Common - LemA Pfl_1298 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 77458690 Common - Transcriptional Regulator, AraC family Pfl_2465 66 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77460504 Common - Arginine N-succinyltransferase Pfl_4283 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 77457003 Common secG preprotein translocase subunit SecG Pfl_0776 22 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 77457243 Common - hypothetical protein Pfl_1016 214 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 77461445 Common - hypothetical protein Pfl_5224 10 None None None 77459871 Common - exonuclease III Pfl_3649 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 77457260 Common - L-carnitine dehydratase/bile acid-inducible protein F Pfl_1033 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 77458840 Common - hypothetical protein Pfl_2615 120 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 77459084 Common - Major facilitator superfamily MFS_1 Pfl_2859 118 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461402 Common - RarD protein Pfl_5181 116 COG2962 RarD, Predicted permeases General function prediction only 77461149 Common - Endonuclease/exonuclease/phosphatase Pfl_4928 12 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 77457994 Common - Protein of unknown function DUF453 Pfl_1767 55 COG2828 COG2828, Uncharacterized protein conserved in bacteria Function unknown 77460082 Common - Glycerophosphoryl diester phosphodiesterase Pfl_3861 166 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 77461494 Common - MltA Pfl_5273 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 77457269 Common - hypothetical protein Pfl_1042 9 None None None 77459117 Common - Two component Transcriptional regulator, Winged helix family Pfl_2892 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77459786 Common - Isochorismatase hydrolase Pfl_3564 116 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 77459899 Common - hypothetical protein Pfl_3677 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 77459073 Common - UDP-glucose 6-dehydrogenase Pfl_2848 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 77458353 Nonpathogen - hypothetical protein Pfl_2126 1 None None None 77458830 Common - Transcriptional Regulator, LysR family Pfl_2605 110 COG0583 LysR, Transcriptional regulator Transcription 77457564 Common - amidase Pfl_1337 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 77460341 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_4120 191 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 77458404 Common - Short-chain dehydrogenase/reductase SDR Pfl_2177 235 COG0623 FabI, Enoyl- acyl-carrier-protein 77458121 Common - aspartate-semialdehyde dehydrogenase Pfl_1894 168 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 77459448 Common - Major facilitator superfamily MFS_1 Pfl_3226 92 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77458565 Common - ABC transporter-like Pfl_2338 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 77460974 Common - ribose-phosphate pyrophosphokinase Pfl_4753 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 77458890 Common - hypothetical protein Pfl_2665 1 None None None 77456716 Common - Small multidrug resistance protein Pfl_0488 135 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 77458805 Common - DinB Pfl_2580 30 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 77458921 Common - Aminotransferase, class I and II Pfl_2696 230 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 77460540 Common - Phosphate transporter Pfl_4319 150 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 77461105 Common - hypothetical protein Pfl_4884 16 None None None 77458420 Common - Arsenical pump membrane protein Pfl_2193 120 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 77461095 Common - glutamate dehydrogenase Pfl_4874 174 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 77461683 Common - ABC transporter-like Pfl_5462 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 77460782 Common - Amino acid permease-associated region Pfl_4561 179 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 77459709 Nonpathogen - hypothetical protein Pfl_3487 1 None None None 77458298 Common - manganese transport protein MntH Pfl_2071 103 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 77458415 Common - Orn/Lys/Arg decarboxylase, major region Pfl_2188 88 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 77458663 Common - Transcriptional Regulator, LysR family Pfl_2438 108 COG0583 LysR, Transcriptional regulator Transcription 77456682 Common - Rhs element Vgr protein Pfl_0454 51 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 77459264 Common - Fimbrial protein Pfl_3042 17 COG3539 FimA, P pilus assembly protein, pilin FimA Cell motility and secretion / Intracellular trafficking and secretion 77457501 Common - Alpha/beta hydrolase Pfl_1274 168 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77461453 Common - 3-hydroxybutyryl-CoA dehydrogenase Pfl_5232 159 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 77459122 Common - Outer membrane autotransporter barrel Pfl_2897 101 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77459055 Common - FAD dependent oxidoreductase Pfl_2830 122 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77459834 Common - NADH dehydrogenase subunit K Pfl_3612 165 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 77457515 Common - hypothetical protein Pfl_1288 3 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77457612 Common - Transcriptional Regulator, LysR family Pfl_1385 99 COG0583 LysR, Transcriptional regulator Transcription 77459020 Common - hypothetical protein Pfl_2795 4 None None None 77460228 Common - hypothetical protein Pfl_4007 3 None None None 77459991 Common - Na+/H+ antiporter NhaC Pfl_3769 29 COG2056 COG2056, Predicted permease General function prediction only 77457585 Common - Protein of unknown function DUF339 Pfl_1358 41 COG2938 COG2938, Uncharacterized conserved protein Function unknown 77458488 Common - Aldehyde dehydrogenase Pfl_2261 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77458481 Common - Epoxide hydrolase-like Pfl_2254 34 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77456747 Common - hypothetical protein Pfl_0519 206 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 77458157 Nonpathogen - hypothetical protein Pfl_1930 1 None None None 77461742 Common - hypothetical protein Pfl_5521 72 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 77457557 Nonpathogen - hypothetical protein Pfl_1330 1 None None None 77460946 Common - hypothetical protein Pfl_4725 6 None None None 77459260 Common - Periplasmic Sensor Hybrid Histidine Kinase Pfl_3038 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77459391 Common - hypothetical protein Pfl_3169 11 None None None 77459452 Common - Glycosyl hydrolase, BNR repeat Pfl_3230 47 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 77457511 Common - Transcriptional Regulator, ArsR family Pfl_1284 50 COG0640 ArsR, Predicted transcriptional regulators Transcription 77461918 Common - Peptidase S8 and S53, subtilisin, kexin, sedolisin Pfl_5698 120 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 77456929 Common - dTDP-glucose 4,6-dehydratase Pfl_0701 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 77461928 Common - Two Component Transcriptional Regulator, LuxR family Pfl_5708 217 COG4566 TtrR, Response regulator Signal transduction mechanisms 77459624 Common - hypothetical protein Pfl_3402 37 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 77457498 Common - Intradiol ring-cleavage dioxygenase Pfl_1271 39 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 77456470 Common - putative amino-acid ABC transporter ATP-binding protein YecC Pfl_0242 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 77458153 Common - hypothetical protein Pfl_1926 1 None None None 77461509 Common - hypothetical protein Pfl_5288 199 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 77460458 Common - Transcriptional Regulator, AraC family Pfl_4237 82 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77459810 Common - arginyl-tRNA-protein transferase Pfl_3588 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 77460328 Nonpathogen - hypothetical protein Pfl_4107 1 None None None 77457956 Common - Ankyrin Pfl_1729 109 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 77459646 Common - Transcriptional Regulator, LysR family Pfl_3424 190 COG0583 LysR, Transcriptional regulator Transcription 77461326 Common - Protein of unknown function DUF805 Pfl_5105 14 COG3152 COG3152, Predicted membrane protein Function unknown 77459475 Common - Periplasmic Sensor Hybrid Histidine Kinase Pfl_3253 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77459546 Common - hypothetical protein Pfl_3324 22 None None None 77458333 Common - Aldo/keto reductase Pfl_2106 165 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 77461822 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pfl_5601 219 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 77456943 Common - Transcriptional Regulator, LysR family Pfl_0715 183 COG0583 LysR, Transcriptional regulator Transcription 77457130 Common - Short-chain dehydrogenase/reductase SDR Pfl_0903 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77458914 Common - hypothetical protein Pfl_2689 12 None None None 77461262 Common - Transcriptional Regulator, AraC family Pfl_5041 144 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77461816 Common - hypothetical protein Pfl_5595 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 77457911 Common - Binding-protein-dependent transport systems inner membrane component Pfl_1684 179 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 77457428 Common - Cold shock protein capB Pfl_1201 178 COG1278 CspC, Cold shock proteins Transcription 77456997 Common - hypothetical protein Pfl_0770 90 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 77458781 Common - GCN5-related N-acetyltransferase Pfl_2556 9 COG3153 COG3153, Predicted acetyltransferase General function prediction only 77460048 Common - undecaprenyl pyrophosphate phosphatase Pfl_3826 198 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 77460470 Common flgD flagellar basal body rod modification protein Pfl_4249 122 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 77461465 Common - choline dehydrogenase Pfl_5244 89 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 77460077 Common - Heavy Metal Sensor Signal Transduction Histidine Kinases (STHK) Pfl_3856 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456370 Common - Major facilitator superfamily MFS_1 Pfl_0142 160 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77458447 Common - Lysine exporter protein (LYSE/YGGA) Pfl_2220 118 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77458788 Common - Peptidase S45, penicillin amidase Pfl_2563 71 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 77460685 Common - Antibiotic biosynthesis monooxygenase Pfl_4464 4 COG1359 COG1359, Uncharacterized conserved protein Function unknown 77457117 Common folX D-erythro-7,8-dihydroneopterin triphosphate 2'-epimerase Pfl_0890 27 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 77459401 Common - General secretion pathway protein G Pfl_3179 105 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77457779 Common flhB flagellar biosynthesis protein FlhB Pfl_1552 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 77456581 Common - Protein of unknown function DUF924 Pfl_0353 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 77457221 Common rnc ribonuclease III Pfl_0994 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 77461898 Common - hypothetical protein Pfl_5678 42 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 77460891 Common - Cell division protein FtsQ Pfl_4670 74 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 77460899 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase Pfl_4678 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 77459988 Common - Protein of unknown function DUF606 Pfl_3766 48 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 77457533 Nonpathogen - hypothetical protein Pfl_1306 1 None None None 77457824 Common - Hydroxypyruvate isomerase Pfl_1597 85 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 77459779 Common - Sulphate transporter Pfl_3557 160 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 77459341 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3119 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 77459694 Common - putative cytochrome p450 oxidoreductase Pfl_3472 67 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 77458959 Common - Two component Transcriptional regulator, Winged helix family Pfl_2734 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77459564 Common - UspA Pfl_3342 56 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 77456813 Common - Urease accessory protein UreD Pfl_0585 83 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 77461615 Common - hypothetical protein Pfl_5394 5 None None None 77460923 Common - Acyltransferase 3 Pfl_4702 76 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 77457943 Common - Smr protein/MutS2-like Pfl_1716 95 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 77460101 Common - hypothetical protein Pfl_3880 2 None None None 77458429 Nonpathogen - hypothetical protein Pfl_2202 1 None None None 77461920 Common - Epoxide hydrolase-like Pfl_5700 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77456838 Common - Multiple antibiotic resistance (MarC)-like proteins Pfl_0610 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 77457874 Common cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase Pfl_1647 124 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 77460906 Common - hypothetical protein Pfl_4685 145 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 77458858 Common - hypothetical protein Pfl_2633 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 77460100 Common fadB multifunctional fatty acid oxidation complex subunit alpha Pfl_3879 162 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 77460590 Common - Binding-protein-dependent transport systems inner membrane component Pfl_4369 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 77456766 Common - replicative DNA helicase Pfl_0538 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 77459197 Common - quinohemoprotein amine dehydrogenase, subunit beta Pfl_2972 5 COG3391 COG3391, Uncharacterized conserved protein Function unknown 77459463 Common - extracellular solute-binding protein, family 1 Pfl_3241 64 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77461176 Common - Protein of unknown function DUF218 Pfl_4955 60 COG1434 COG1434, Uncharacterized conserved protein Function unknown 77460816 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pfl_4595 200 COG0388 COG0388, Predicted amidohydrolase General function prediction only 77461911 Common - Transcriptional Regulator, LysR family Pfl_5691 141 COG0583 LysR, Transcriptional regulator Transcription 77456673 Common - potassium efflux protein KefA Pfl_0445 225 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77459884 Common - Peptidase M14, carboxypeptidase A Pfl_3662 31 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 77459277 Common - Alpha/beta hydrolase fold Pfl_3055 84 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77461630 Common - Transcriptional Regulator, TetR family Pfl_5409 21 COG1309 AcrR, Transcriptional regulator Transcription 77457667 Common - hypothetical protein Pfl_1440 1 None None None 77459153 Common - glutathione reductase Pfl_2928 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 77461621 Common - Metal dependent phosphohydrolase, HD region Pfl_5400 23 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 77461875 Common - Cobalamin synthesis protein/P47K Pfl_5655 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 77459362 Common - PAS/PAC Sensor Hybrid Histidine Kinase Pfl_3140 217 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77459074 Common - 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferase of PMT family-like Pfl_2849 3 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 77456730 Common - hypothetical protein Pfl_0502 49 COG3577 COG3577, Predicted aspartyl protease General function prediction only 77461590 Common - ABC transporter-like Pfl_5369 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77458461 Common - Short-chain dehydrogenase/reductase SDR Pfl_2234 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 77459369 Common - N-ethylammeline chlorohydrolase Pfl_3147 150 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 77457166 Common - Fusaric acid resistance protein conserved region Pfl_0939 48 COG1289 COG1289, Predicted membrane protein Function unknown 77461026 Common - glutamyl-Q tRNA(Asp) synthetase Pfl_4805 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 77456344 Common - Transcriptional Regulator, LysR family Pfl_0116 170 COG0583 LysR, Transcriptional regulator Transcription 77460367 Common - lipoprotein, putative Pfl_4146 1 None None None 77460139 Common - Sigma-54 Specific Transcriptional Regulator, Fis family Pfl_3918 168 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77459815 Common - Isocitrate dehydrogenase NADP-dependent Pfl_3593 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 77461651 Common - extracellular solute-binding protein, family 1 Pfl_5430 123 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 77456308 Common - hypothetical protein Pfl_0080 4 None None None 77457489 Common - Phosphate transporter Pfl_1262 143 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 77460871 Common - disulfide bond formation protein B Pfl_4650 7 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 77460606 Common - Arginine/ornithine antiporter Pfl_4385 69 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 77457969 Common - Mg2+ transporter protein, CorA-like Pfl_1742 161 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 77460214 Common - Transcriptional Regulator, LysR family Pfl_3993 182 COG0583 LysR, Transcriptional regulator Transcription 77460574 Common - acyl-CoA synthetase Pfl_4353 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77460334 Common - OmpA/MotB Pfl_4113 171 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77461520 Common - malonate decarboxylase subunit beta Pfl_5299 192 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 77460069 Common - Anti-Sigma-factor antagonist (STAS) Pfl_3848 7 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 77458966 Common - Cytochrome c, class I Pfl_2741 58 COG2863 COG2863, Cytochrome c553 Energy production and conversion 77456626 Common - Sporulation-like Pfl_0398 21 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 77458636 Common - Phytanoyl-CoA dioxygenase Pfl_2409 15 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 77458923 Common - Formate dehydrogenase, alpha subunit, anaerobic Pfl_2698 181 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 77459226 Nonpathogen - hypothetical protein Pfl_3004 1 None None None 77458012 Common - nitrate-binding protein NasS, putative Pfl_1785 87 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 77460635 Common - Ferritin and Dps Pfl_4414 145 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 77459339 Common - ABC transporter-like Pfl_3117 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 77457194 Common - Lysine-arginine-ornithine-binding periplasmic protein Pfl_0967 176 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77459408 Common - GCN5-related N-acetyltransferase Pfl_3186 12 COG0456 RimI, Acetyltransferases General function prediction only 77461411 Common - PepSY-associated TM helix Pfl_5190 45 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 77457772 Common fliL flagellar basal body-associated protein FliL Pfl_1545 30 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 77461423 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_5202 192 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 77456576 Common - hypothetical protein Pfl_0348 8 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 77459332 Common - Periplasmic binding protein/LacI transcriptional regulator Pfl_3110 63 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 77460301 Common - N-ethylammeline chlorohydrolase Pfl_4080 170 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 77459182 Common - cytochrome c-type biogenesis protein CcmE Pfl_2957 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 77456972 Nonpathogen - hypothetical protein Pfl_0745 1 None None None 77457634 Common - Allophanate hydrolase subunit 2 Pfl_1407 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 77457734 Common flgL flagellar hook-associated protein FlgL Pfl_1507 104 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 77457431 Common - Metallophosphoesterase Pfl_1204 49 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 77461793 Common - hypothetical protein Pfl_5572 2 None None None 77456469 Common - hypothetical protein Pfl_0241 1 None None None 77461220 Common - hypothetical protein Pfl_4999 7 COG5445 COG5445, Predicted secreted protein Function unknown 77457547 Common - hypothetical protein Pfl_1320 5 None None None 77460956 Common - Transcriptional Regulator, MerR family Pfl_4735 37 COG0789 SoxR, Predicted transcriptional regulators Transcription 77456897 Common - regulatory protein, ArsR Pfl_0669 34 COG0640 ArsR, Predicted transcriptional regulators Transcription 77460415 Common - short chain dehydrogenase Pfl_4194 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77459943 Common - Mandelate racemase/muconate lactonizing enzyme Pfl_3721 57 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 77458766 Common - NodS Pfl_2541 21 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 77460290 Common - Glycosyltransferase-like Pfl_4069 37 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77461394 Common - Biotin biosynthesis protein BioC Pfl_5173 193 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77458843 Common - Mg2+ transporter protein, CorA-like Pfl_2618 27 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 77456604 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_0376 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77461332 Common - cAMP-regulatory protein Pfl_5111 149 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 77461266 Common - hypothetical protein Pfl_5045 6 None None None 77461803 Common - hypothetical protein Pfl_5582 1 None None None 77461891 Common - dihydrolipoamide dehydrogenase Pfl_5671 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 77459654 Common - Cobalamin synthesis protein/P47K Pfl_3432 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 77461239 Common - riboflavin synthase subunit alpha Pfl_5018 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 77459714 Nonpathogen - hypothetical protein Pfl_3492 1 None None None 77460274 Common - Glycosyl transferase, family 4 Pfl_4053 151 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 77458160 Common rpmI 50S ribosomal protein L35 Pfl_1933 146 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 77457185 Common - alginate biosynthesis protein Alg44 Pfl_0958 3 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77457933 Common - Polysaccharide deacetylase Pfl_1706 89 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 77461609 Common - hypothetical protein Pfl_5388 18 None None None 77457499 Common - Citrate-proton symport Pfl_1272 129 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77459315 Nonpathogen - hypothetical protein Pfl_3093 1 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 77456338 Common - hypothetical protein Pfl_0110 1 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 77459224 Nonpathogen - hypothetical protein Pfl_3002 1 None None None 77461516 Common - Malonate transporter MadL subunit Pfl_5295 11 None None None 77457048 Common - Two Component Transcriptional Regulator, Fis family Pfl_0821 174 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 77461420 Common - hypothetical protein Pfl_5199 4 None None None 77458594 Common - Endoribonuclease L-PSP Pfl_2367 29 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77457718 Common - Protein of unknown function DUF1289 Pfl_1491 3 COG3313 COG3313, Predicted Fe-S protein General function prediction only 77456540 Common - ABC transporter-like Pfl_0312 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 77457302 Common - Extensin-like protein Pfl_1075 37 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 77456559 Common - Peptidase S41A, protease Pfl_0331 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 77456546 Nonpathogen - hypothetical protein Pfl_0318 1 None None None 77461269 Common - Glutathionylspermidine synthase Pfl_5048 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 77460461 Common - Two component Transcriptional regulator, Winged helix family Pfl_4240 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77456708 Common - O-antigen polymerase Pfl_0480 11 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 77459482 Common - extracellular solute-binding protein, family 1 Pfl_3260 130 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77459348 Common - RNA polymerase sigma factor Pfl_3126 51 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77460035 Common - Copper resistance D Pfl_3813 17 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 77460468 Common - Hemolysin-type calcium-binding region Pfl_4247 107 None None None 77459010 Common - hypothetical protein Pfl_2785 55 COG3781 COG3781, Predicted membrane protein Function unknown 77457819 Common - Ion transport protein Pfl_1592 107 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 77456442 Common - Sulfatase Pfl_0214 88 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 77459745 Common - Aldo/keto reductase Pfl_3523 156 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 77458250 Common - sugar transferase Pfl_2023 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 77458539 Common - Glycine hydroxymethyltransferase Pfl_2312 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 77458873 Common - CheB methylesterase Pfl_2648 149 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 77459048 Common - Polysaccharide biosynthesis protein Pfl_2823 72 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 77458740 Nonpathogen - hypothetical protein Pfl_2515 1 None None None 77458389 Common - Multi-sensor Signal Transduction Histidine Kinase Pfl_2162 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 77459230 Common - hypothetical protein Pfl_3008 12 None None None 77460951 Common hemH ferrochelatase Pfl_4730 155 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 77457810 Common - Periplasmic protein thiol:disulfide oxidoreductase DsbE Pfl_1583 141 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 77459254 Nonpathogen - hypothetical protein Pfl_3032 1 None None None 77461131 Common - Transcriptional Regulator, IclR family Pfl_4910 116 COG1414 IclR, Transcriptional regulator Transcription 77461068 Common - hypothetical protein Pfl_4847 3 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 77458285 Common - Isochorismatase hydrolase Pfl_2058 109 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 77456506 Nonpathogen - Rickettsia 17 kDa surface antigen Pfl_0278 1 None None None 77459994 Common - Two component Transcriptional regulator, Winged helix family Pfl_3772 209 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77457121 Common - Transcriptional Regulator, MerR family Pfl_0894 62 COG0789 SoxR, Predicted transcriptional regulators Transcription 77460958 Common - hypothetical protein Pfl_4737 28 None None None 77456852 Common - hypothetical protein Pfl_0624 22 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 77458029 Common - hypothetical protein Pfl_1802 31 COG4307 COG4307, Uncharacterized protein conserved in bacteria Function unknown 77459352 Common - Strictosidine synthase Pfl_3130 24 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 77459250 Nonpathogen - hypothetical protein Pfl_3028 1 None None None 77461213 Common - ethanolamine ammonia-lyase small subunit Pfl_4992 54 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 77461025 Common - Transcriptional regulators, TraR/DksA family Pfl_4804 145 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 77456493 Common - RNA-binding S4 Pfl_0265 96 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 77458434 Common - Protein of unknown function DUF461 Pfl_2207 80 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 77461808 Nonpathogen - hypothetical protein Pfl_5587 1 None None None 77457579 Common - membrane protein TctB, putative Pfl_1352 4 None None None 77458462 Common - Fumarylacetoacetate (FAA) hydrolase Pfl_2235 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 77459141 Common - RarD protein Pfl_2916 93 COG2962 RarD, Predicted permeases General function prediction only 77458403 Common - Putative diguanylate cyclase (GGDEF domain) with GAF sensor domain Pfl_2176 185 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77458520 Common - GABA permease Pfl_2293 163 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 77456271 Common - hypothetical protein Pfl_0043 7 None None None 77460281 Common ihfB integration host factor subunit beta Pfl_4060 203 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 77458435 Common - Electron transport protein SCO1/SenC Pfl_2208 103 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 77461907 Common - Glycosyl transferase, group 1 Pfl_5687 182 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77456411 Common - von Willebrand factor, type A Pfl_0183 47 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 77460317 Common - Acetyl-CoA C-acyltransferase Pfl_4096 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77460402 Common - ABC transporter-like Pfl_4181 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 77458260 Common - hypothetical protein Pfl_2033 7 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 77457690 Common - VCBS Pfl_1463 174 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 77460195 Common - Two Component Transcriptional Regulator, LuxR family Pfl_3974 221 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77460678 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_4457 221 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77460515 Common - hypothetical protein Pfl_4294 1 None None None 77460520 Common - hypothetical protein Pfl_4299 4 None None None 77459184 Common - Cytochrome c-type biogenesis protein CcmC Pfl_2959 121 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 77456691 Common aceE pyruvate dehydrogenase subunit E1 Pfl_0463 130 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 77458210 Common - hypothetical protein Pfl_1983 5 None None None 77459842 Nonpathogen - hypothetical protein Pfl_3620 1 None None None 77458518 Nonpathogen - hypothetical protein Pfl_2291 1 None None None 77457740 Common - hypothetical protein Pfl_1513 47 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 77457684 Common - Putative agmatinase Pfl_1457 160 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 77461853 Common - regulatory protein GntR, HTH Pfl_5633 189 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 77457927 Common - hypothetical protein Pfl_1700 17 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 77457675 Common - Protein of unknown function DUF6, transmembrane Pfl_1448 129 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77457171 Common - Transcriptional Regulator, LysR family Pfl_0944 175 COG0583 LysR, Transcriptional regulator Transcription 77460735 Common - hypothetical protein Pfl_4514 1 None None None 77460292 Common - NAD-dependent epimerase/dehydratase Pfl_4071 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77458115 Common - Transcriptional Regulator, LysR family Pfl_1888 193 COG0583 LysR, Transcriptional regulator Transcription 77457829 Common - VacJ-like lipoprotein Pfl_1602 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 77456790 Common - Urease accessory protein UreF Pfl_0562 74 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 77457464 Common - lipoprotein, putative Pfl_1237 2 COG3650 COG3650, Predicted membrane protein Function unknown 77456354 Common - Amino acid adenylation:Thioester reductase Pfl_0126 200 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77456752 Common - GTP-binding protein, HSR1-like Pfl_0524 211 COG2262 HflX, GTPases General function prediction only 77458145 Nonpathogen - hypothetical protein Pfl_1918 1 None None None 77461185 Common lipB lipoyltransferase Pfl_4964 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 77457360 Common - 4Fe-4S ferredoxin, iron-sulfur binding Pfl_1133 132 COG1146 COG1146, Ferredoxin Energy production and conversion 77461000 Common - hypothetical protein Pfl_4779 7 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 77459436 Common - hypothetical protein Pfl_3214 1 None None None 77460962 Common - Cyclopropane-fatty-acyl-phospholipid synthase Pfl_4741 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 77459688 Common - dihydrolipoamide dehydrogenase Pfl_3466 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 77461696 Common - hypothetical protein Pfl_5475 4 None None None 77456408 Common - haemin storage system, HmsS protein Pfl_0180 3 None None None 77457372 Common - Phage tail sheath protein FI-like Pfl_1145 21 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 77459529 Common - hypothetical protein Pfl_3307 31 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 77458374 Common - Molybdopterin cofactor biosynthesis MoaC region Pfl_2147 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 77458492 Common - Amino acid adenylation Pfl_2265 228 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77458001 Common - CrfX protein Pfl_1774 1 None None None 77460924 Common - OmpA/MotB Pfl_4703 160 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77461700 Common - hypothetical protein Pfl_5479 11 COG5589 COG5589, Uncharacterized conserved protein Function unknown 77461321 Common anmK anhydro-N-acetylmuramic acid kinase Pfl_5100 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 77459299 Common - Sigma-54 Specific Transcriptional Regulator containing PAS, and Fis DNA-binding domains Pfl_3077 173 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 77459374 Common - LexA repressor Pfl_3152 172 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 77460125 Common - Protein of unknown function DUF6, transmembrane Pfl_3904 82 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 77457796 Common - flagellar motor protein MotD Pfl_1569 139 COG1360 MotB, Flagellar motor protein Cell motility and secretion 77459292 Common - hypothetical protein Pfl_3070 1 None None None 77461006 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Pfl_4785 135 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 77460134 Common - Lysine exporter protein (LYSE/YGGA) Pfl_3913 60 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77461942 Common - hypothetical protein Pfl_5725 18 None None None 77461429 Common - serine hydroxymethyltransferase Pfl_5208 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 77456715 Common - FAD dependent oxidoreductase Pfl_0487 10 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 77461821 Common - Histone-like DNA-binding protein Pfl_5600 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 77460601 Common - Heme oxygenase Pfl_4380 9 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 77459726 Nonpathogen - hypothetical protein Pfl_3504 1 None None None 77460746 Common - Molybdopterin oxidoreductase Pfl_4525 187 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 77458024 Common - Molybdopterin dehydrogenase, FAD-binding Pfl_1797 122 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 77458235 Common - Protein of unknown function DUF891 Pfl_2008 42 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 77459819 Common - hypothetical protein Pfl_3597 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 77460120 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pfl_3899 214 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 77458257 Common - hypothetical protein Pfl_2030 9 None None None 77461294 Common rpsC 30S ribosomal protein S3 Pfl_5073 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 77459557 Nonpathogen - hypothetical protein Pfl_3335 1 None None None 77460622 Common - OmpA/MotB Pfl_4401 159 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77460597 Common - glyceraldehyde-3-phosphate dehydrogenase Pfl_4376 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 77459626 Common - Protein of unknown function DUF876 Pfl_3404 18 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 77458691 Common - hypothetical protein Pfl_2466 9 None None None 77459190 Common benD 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase Pfl_2965 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77461642 Common - Adenylate cyclase Pfl_5421 49 COG3025 COG3025, Uncharacterized conserved protein Function unknown 77459522 Common - hypothetical protein Pfl_3300 15 None None None 77458698 Common - Ferredoxin Pfl_2473 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 77461087 Common - hypothetical protein Pfl_4866 55 COG2862 COG2862, Predicted membrane protein Function unknown 77456438 Common - Binding-protein-dependent transport systems inner membrane component Pfl_0210 141 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 77458888 Common - hypothetical protein Pfl_2663 3 None None None 77459068 Common - bifunctional UDP-glucuronic acid decarboxylase/UDP-4-amino-4-deoxy-L-arabinose formyltransferase Pfl_2843 244 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 77456878 Common - Flp/Fap pilin component Pfl_0650 3 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 77460551 Common - Pyridoxamine 5'-phosphate oxidase-like, FMN-binding Pfl_4330 48 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 77461807 Common - Protein of unknown function DUF879 Pfl_5586 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 77457906 Common - Peptidase S41A, protease Pfl_1679 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 77461061 Common - Two Component, Sigma-54 Specific, Transcriptional Regulator, Fis family Pfl_4840 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77459922 Common pbpG D-alanyl-D-alanine endopeptidase Pfl_3700 119 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 77461565 Common - Transcriptional Regulator, TetR family Pfl_5344 37 COG1309 AcrR, Transcriptional regulator Transcription 77456777 Common - Transcriptional Regulator, LysR family Pfl_0549 174 COG0583 LysR, Transcriptional regulator Transcription 77458096 Common - N-acetyltransferase Pfl_1869 45 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 77460849 Common - HNH endonuclease Pfl_4628 15 COG3183 COG3183, Predicted restriction endonuclease Defense mechanisms 77457331 Common frr ribosome recycling factor Pfl_1104 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 77457900 Common - Transcriptional Regulator, XRE family Pfl_1673 1 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 77461478 Nonpathogen - hypothetical protein Pfl_5257 1 None None None 77457294 Common - hypothetical protein Pfl_1067 5 None None None 77456945 Common - Antibiotic biosynthesis monooxygenase Pfl_0717 30 COG1359 COG1359, Uncharacterized conserved protein Function unknown 77459035 Common - PAS/PAC Sensor Hybrid Histidine Kinase Pfl_2810 219 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77461735 Common - Nucleotidyl transferase Pfl_5514 142 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 77459027 Common - extracellular solute-binding protein, family 3 Pfl_2802 173 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 161485588 Common secA preprotein translocase subunit SecA Pfl_4428 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 77460726 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Pfl_4505 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77456900 Common - 2OG-Fe(II) oxygenase Pfl_0672 55 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 77461602 Common - threonine dehydratase Pfl_5381 208 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 77460041 Common - hypothetical protein Pfl_3819 2 None None None 77458607 Nonpathogen - hypothetical protein Pfl_2380 1 None None None 77461414 Common - hypothetical protein Pfl_5193 29 COG4452 CreD, Inner membrane protein involved in colicin E2 resistance Defense mechanisms 77459866 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_3644 128 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77460364 Common - Senescence marker protein-30 (SMP-30) Pfl_4143 75 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 77459578 Common - Major facilitator superfamily MFS_1 Pfl_3356 46 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77456239 Common - DNA-3-methyladenine glycosylase I Pfl_0011 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 77461488 Common - transketolase Pfl_5267 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 77460097 Common - DNA topoisomerase I Pfl_3876 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 77458346 Common - Binding-protein-dependent transport systems inner membrane component Pfl_2119 205 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 77456887 Common - Major facilitator superfamily MFS_1 Pfl_0659 21 None None None 77459593 Common - Carbonate dehydratase Pfl_3371 155 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 77460071 Common - VacJ-like lipoprotein Pfl_3850 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 77457491 Common - hypothetical protein Pfl_1264 1 None None None 77456232 Common gyrB DNA gyrase subunit B Pfl_0004 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 77457075 Common - FagA protein Pfl_0848 2 None None None 77461052 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Pfl_4831 183 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 77461715 Common - nucleoside diphosphate kinase regulator Pfl_5494 70 COG0782 GreA, Transcription elongation factor Transcription 77459925 Common - hypothetical protein Pfl_3703 14 None None None 77460998 Common - hypothetical protein Pfl_4777 6 None None None 77457596 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Pfl_1369 220 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77456736 Nonpathogen - hypothetical protein Pfl_0508 3 None None None 77460389 Common - Protein of unknown function DUF182 Pfl_4168 113 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 77460641 Common - MscS Mechanosensitive ion channel Pfl_4420 205 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77461643 Common - Transcriptional Regulator, AsnC family Pfl_5422 159 COG1522 Lrp, Transcriptional regulators Transcription 77460868 Common - Cytochrome-c oxidase Pfl_4647 164 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 77457191 Common moaC molybdenum cofactor biosynthesis protein C Pfl_0964 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 77457629 Common - hypothetical protein Pfl_1402 6 None None None 77458166 Common - DNA helicase-related protein Pfl_1939 20 None None None 77458680 Common - Response regulator receiver domain protein (CheY) Pfl_2455 78 COG4566 TtrR, Response regulator Signal transduction mechanisms 77460876 Common - GCN5-related N-acetyltransferase Pfl_4655 2 COG0456 RimI, Acetyltransferases General function prediction only 77457961 Common - hypothetical protein Pfl_1734 5 None None None 77459840 Common - outer membrane porin Pfl_3618 9 None None None 77458222 Common - hypothetical protein Pfl_1995 13 None None None 77461112 Common - hypothetical protein Pfl_4891 4 None None None 77461350 Common - Heat shock protein DnaJ-like Pfl_5129 63 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 77458034 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_1807 95 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 77459425 Common - Antibiotic biosynthesis monooxygenase Pfl_3203 2 COG1359 COG1359, Uncharacterized conserved protein Function unknown 77461124 Common aroE shikimate 5-dehydrogenase Pfl_4903 214 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 77459604 Common - Transcriptional Regulator, LysR family Pfl_3382 95 COG0583 LysR, Transcriptional regulator Transcription 77460547 Common - Unknown Sigma-factor Pfl_4326 41 COG4941 COG4941, Predicted RNA polymerase sigma factor containing a TPR repeat domain Transcription 77459870 Common - acetyltransferase, GNAT family Pfl_3648 9 COG0456 RimI, Acetyltransferases General function prediction only 77460706 Common - Lysine exporter protein (LYSE/YGGA) Pfl_4485 79 COG1279 COG1279, Lysine efflux permease General function prediction only 77457720 Common - Amino acid permease-associated region Pfl_1493 162 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 77460236 Common - ABC transporter-like Pfl_4015 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 77456260 Common - Integral membrane protein TerC Pfl_0032 101 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 77457220 Common - Peptidase S26A, signal peptidase I Pfl_0993 209 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 77461794 Common - hypothetical protein Pfl_5573 3 None None None 77457696 Common - Transcriptional Regulator, MarR family Pfl_1469 91 COG1846 MarR, Transcriptional regulators Transcription 77459355 Common - Anti-Sigma-factor antagonist (STAS) Pfl_3133 33 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 77456603 Common - extracellular solute-binding protein, family 3 Pfl_0375 179 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77457289 Common - lipoprotein, putative Pfl_1062 1 None None None 77459721 Nonpathogen - hypothetical protein Pfl_3499 1 None None None 77460184 Common - Protein of unknown function DUF903 Pfl_3963 2 None None None 77456847 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit Pfl_0619 184 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 77457851 Common - Thioesterase superfamily Pfl_1624 25 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 77459091 Common - Enoyl-CoA hydratase/isomerase Pfl_2866 188 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77456869 Nonpathogen - hypothetical protein Pfl_0641 1 None None None 77459908 Common - 1-aminocyclopropane-1-carboxylate deaminase, putative Pfl_3686 29 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 77457756 Common - Flagellar hook-associated 2-like Pfl_1529 82 COG1345 FliD, Flagellar capping protein Cell motility and secretion 77456590 Common - Substrate-binding region of ABC-type glycine betaine transport system Pfl_0362 43 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 77458731 Common - GCN5-related N-acetyltransferase Pfl_2506 105 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 77459070 Common arnT 4-amino-4-deoxy-L-arabinose transferase Pfl_2845 94 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 77461371 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Pfl_5150 206 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77458185 Common - Transcriptional Regulator, Winged helix family Pfl_1958 74 COG3903 COG3903, Predicted ATPase General function prediction only 77457383 Common - Sigma-factor domain protein Pfl_1156 5 None None None 77461934 Common - Transcriptional Regulator, AraC family Pfl_5716 88 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77457876 Common - Phosphoglycerate/bisphosphoglycerate mutase Pfl_1649 145 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 77459803 Common - Uroporphyrin-III C-methyltransferase-like Pfl_3581 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 77458885 Common - GTPase subunit of restriction endonuclease-like Pfl_2660 46 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 77456549 Common - AsmA Pfl_0321 64 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 77461278 Common - 30S ribosomal protein S11 Pfl_5057 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 77457320 Common - 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase, putative Pfl_1093 39 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 77457601 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Pfl_1374 218 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 77460396 Common lpxK tetraacyldisaccharide 4'-kinase Pfl_4175 122 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 77459082 Common - Polysaccharide deacetylase Pfl_2857 99 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 77458986 Common - Transcriptional Regulator, AraC family Pfl_2761 69 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77457631 Common - General substrate transporter Pfl_1404 214 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77459638 Common - hypothetical protein Pfl_3416 22 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 77458128 Common - Colicin V production protein Pfl_1901 63 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 77456298 Common - Electron transport protein SCO1/SenC Pfl_0070 110 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 77457922 Common minC septum formation inhibitor Pfl_1695 92 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 77459653 Common - Phenylacrylic acid decarboxylase Pfl_3431 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 77460783 Common - hypothetical protein Pfl_4562 2 None None None 77459915 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Pfl_3693 168 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 77461367 Common - Peptidase M22, glycoprotease Pfl_5146 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 77459858 Common - Sigma-54 Specific Transcriptional Regulator containing GAF, and Fis DNA-binding domains Pfl_3636 177 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 77457502 Common - Carboxymuconolactone decarboxylase Pfl_1275 88 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 77456394 Common - hypothetical protein Pfl_0166 76 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 77457723 Common - hypothetical protein Pfl_1496 1 None None None 77456319 Common - transferase hexapeptide repeat Pfl_0091 188 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 77457214 Common - hypothetical protein Pfl_0987 1 None None None 77458069 Common - Major facilitator superfamily MFS_1 Pfl_1842 27 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77460829 Common hscA chaperone protein HscA Pfl_4608 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 77456309 Common - Sulphate transporter Pfl_0081 158 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 77459245 Common - hypothetical protein Pfl_3023 32 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 77461047 Common - hypothetical protein Pfl_4826 17 COG3235 COG3235, Predicted membrane protein Function unknown 77460119 Common - Transcriptional Regulator, LysR family Pfl_3898 183 COG0583 LysR, Transcriptional regulator Transcription 77458934 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Pfl_2709 182 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77456312 Common - Cytochrome c, class I Pfl_0084 75 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 77458004 Common - OmpF Pfl_1777 168 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 77459336 Common - predicted inner membrane peptidase Pfl_3114 185 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 77458998 Common - Sodium:dicarboxylate symporter Pfl_2773 160 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 77459664 Common - putative oxidoreductase Pfl_3442 219 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 77457666 Common - hypothetical protein Pfl_1439 5 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 77458798 Common - Xanthine/uracil permease Pfl_2573 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 77457417 Common - GCN5-related N-acetyltransferase Pfl_1190 53 COG0456 RimI, Acetyltransferases General function prediction only 77458689 Common - OsmC-like protein Pfl_2464 90 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77457444 Common - hypothetical protein Pfl_1217 12 COG5608 COG5608, Conserved secreted protein Function unknown 77458008 Common - Nitrite and sulphite reductase 4Fe-4S region Pfl_1781 212 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 77456677 Common - Protein of unknown function DUF710 Pfl_0449 1 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 77456816 Common - inner-membrane translocator Pfl_0588 148 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 77459201 Common - Possible Transcriptional Regulator, Fis family Pfl_2976 169 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 77457439 Common - hypothetical protein Pfl_1212 58 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 77461525 Common - CheA Signal Transduction Histidine Kinases (STHK) Pfl_5304 223 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 77460718 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_4497 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456789 Common - Urease accessory protein UreG Pfl_0561 123 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 77458246 Common - Glycosyl transferase, group 1 Pfl_2019 200 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77458578 Common - hypothetical protein Pfl_2351 27 COG5649 COG5649, Uncharacterized conserved protein Function unknown 77461833 Common - Phosphate transport system permease protein 1 Pfl_5612 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 77457918 Common - hypothetical protein Pfl_1691 5 None None None 77457566 Common - hypothetical protein Pfl_1339 57 COG3665 COG3665, Uncharacterized conserved protein Function unknown 77460842 Common tgt queuine tRNA-ribosyltransferase Pfl_4621 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 77459275 Nonpathogen - hypothetical protein Pfl_3053 2 None None None 77461152 Common - putative sulfonate/nitrate transport system substrate-binding protein Pfl_4931 89 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 77459329 Common metH B12-dependent methionine synthase Pfl_3107 179 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 77458392 Common - Transcriptional Regulator, AraC family Pfl_2165 138 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77457028 Common - Ornithine decarboxylase Pfl_0801 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 77461950 Common - F0F1 ATP synthase subunit delta Pfl_5733 184 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 77460830 Common hscB co-chaperone HscB Pfl_4609 56 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 77458031 Common - hypothetical protein Pfl_1804 8 None None None 77460193 Common - Putative diguanylate phosphodiesterase (EAL domain) Pfl_3972 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77458951 Common - Major facilitator superfamily MFS_1 Pfl_2726 181 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77457349 Common - Septum formation initiator Pfl_1122 60 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 77459392 Common - Plasmid stabilization system Pfl_3170 23 COG3668 ParE, Plasmid stabilization system protein General function prediction only 77459771 Common - hypothetical protein Pfl_3549 1 None None None 77457607 Common - hypothetical protein Pfl_1380 26 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 77457868 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase Pfl_1641 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 77461939 Common - hypothetical protein Pfl_5722 16 None None None 77456801 Common - Transcriptional Regulator, AraC family Pfl_0573 87 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77459198 Common - hypothetical protein Pfl_2973 5 None None None 77457929 Common - Protein of unknown function DUF989 Pfl_1702 38 COG3748 COG3748, Predicted membrane protein Function unknown 77461685 Common - polyphosphate kinase Pfl_5464 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 77459669 Common - Copper resistance D Pfl_3447 31 COG1276 PcoD, Putative copper export protein Inorganic ion transport and metabolism 77458170 Nonpathogen - hypothetical protein Pfl_1943 1 None None None 77457144 Common - Phosphate-starvation-inducible E Pfl_0917 17 COG3223 COG3223, Predicted membrane protein Function unknown 77460709 Common - hypothetical protein Pfl_4488 30 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 77459097 Common - Iron permease FTR1 Pfl_2872 85 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 77460349 Common - PAAR Pfl_4128 13 COG4104 COG4104, Uncharacterized conserved protein Function unknown 77458655 Nonpathogen - hypothetical protein Pfl_2430 1 None None None 77458043 Common - Copper-translocating P-type ATPase Pfl_1816 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 77458200 Common - General secretion pathway protein G Pfl_1973 76 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77457432 Common - DEAD/DEAH box helicase-like Pfl_1205 136 COG1201 Lhr, Lhr-like helicases General function prediction only 77457620 Common - hypothetical protein Pfl_1393 2 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 77458726 Common - hypothetical protein Pfl_2501 15 None None None 77456302 Common - hypothetical protein Pfl_0074 49 COG3346 COG3346, Uncharacterized conserved protein Function unknown 77456903 Common - hydroxydechloroatrazine ethylaminohydrolase Pfl_0675 173 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 77457032 Common - Substrate-binding region of ABC-type glycine betaine transport system Pfl_0805 90 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 77456424 Common - Sulfate ABC transporter, permease protein CysW Pfl_0196 221 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 77460778 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pfl_4557 206 COG0388 COG0388, Predicted amidohydrolase General function prediction only 161485591 Common - RNA polymerase sigma factor Pfl_3746 137 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77456964 Common - hypothetical protein Pfl_0737 2 None None None 77458615 Common - Transcriptional Regulator, AraC family Pfl_2388 76 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77457118 Common - GTP cyclohydrolase I Pfl_0891 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 77461883 Common - dihydroorotase Pfl_5663 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 77456378 Common - lipoprotein, putative Pfl_0150 1 None None None 77461317 Common - biotin--protein ligase Pfl_5096 230 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 77461705 Common - HemY-like Pfl_5484 53 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 77457445 Common - hypothetical protein Pfl_1218 87 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 77459414 Common - hypothetical protein Pfl_3192 2 None None None 77459955 Common - hypothetical protein Pfl_3733 28 COG5579 COG5579, Uncharacterized conserved protein Function unknown 77458469 Common - Sodium:dicarboxylate symporter Pfl_2242 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 77457651 Common - hypothetical protein Pfl_1424 16 None None None 77459778 Common - Alkylhydroperoxidase AhpD core Pfl_3556 80 COG2128 COG2128, Uncharacterized conserved protein Function unknown 77458713 Common - hypothetical protein Pfl_2488 2 None None None 77460255 Common - Amino acid permease-associated region Pfl_4034 172 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 77461745 Common dadX alanine racemase Pfl_5524 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 77458822 Common - hypothetical protein Pfl_2597 2 None None None 77456767 Common - hypothetical protein Pfl_0539 1 None None None 77458670 Common - NADH:flavin oxidoreductase/NADH oxidase Pfl_2445 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77457713 Common - intracellular septation protein A Pfl_1486 88 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 77458097 Common - hypothetical protein Pfl_1870 4 None None None 77456820 Common - Periplasmic binding protein Pfl_0592 85 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 77460671 Common - hypothetical protein Pfl_4450 67 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 77456648 Common - Predicted transcriptional regulator Pfl_0420 40 COG3636 COG3636, Predicted transcriptional regulator Transcription 77459130 Common - Aminotransferase, class I and II Pfl_2905 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 77458349 Common - Glutamate--ammonia ligase Pfl_2122 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 77459003 Common - Protein-methionine-S-oxide reductase Pfl_2778 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 77457858 Common - hypothetical protein Pfl_1631 17 None None None 77460943 Common - lipoprotein, putative Pfl_4722 4 None None None 77456288 Common - zinc uptake regulation protein, putative Pfl_0060 112 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 77458179 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_1952 192 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77456615 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase Pfl_0387 221 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77460177 Common - Histidine kinase, dimerization and phosphoacceptor region Pfl_3956 148 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 77461346 Common - Spermidine/putrescine ABC transporter ATP-binding subunit Pfl_5125 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77459081 Common - Polysaccharide deacetylase Pfl_2856 85 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 77461431 Common - Aromatic amino acid beta-eliminating lyase/threonine aldolase Pfl_5210 113 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 77460907 Common gmhA phosphoheptose isomerase Pfl_4686 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 77456829 Common - cobalt-precorrin-6x reductase Pfl_0601 60 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 77460698 Common - regulatory protein Pfl_4477 113 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77459125 Common - regulatory protein, LacI Pfl_2900 125 COG1609 PurR, Transcriptional regulators Transcription 77460427 Common - Possible Phosphohistidine Phosphatase, SixA Pfl_4206 28 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 77456663 Common - Glycosyl transferase, family 2 Pfl_0435 108 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77458555 Common - Protein of unknown function DUF796 Pfl_2328 32 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 77460837 Common - Inositol monophosphatase Pfl_4616 213 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 77461399 Common - Transcriptional regulator, ModE family Pfl_5178 55 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 77457159 Common - Transcriptional Regulator, AraC family Pfl_0932 109 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77460714 Common - multidrug efflux protein Pfl_4493 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77460663 Common - hypothetical protein Pfl_4442 4 None None None 77459642 Common - hypothetical protein Pfl_3420 133 COG2860 COG2860, Predicted membrane protein Function unknown 77458868 Common - hypothetical protein Pfl_2643 59 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77458623 Common - Heavy metal efflux pump CzcA Pfl_2396 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 77456770 Common - hypothetical protein Pfl_0542 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 77459322 Common - Cobalt transporter subunit CbtB, putative Pfl_3100 10 None None None 77457091 Common - Protein of unknown function DUF140 Pfl_0864 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 77457481 Common - General substrate transporter Pfl_1254 128 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77460585 Common - DNA-binding transcriptional regulator HexR Pfl_4364 95 COG1737 RpiR, Transcriptional regulators Transcription 77460357 Common - Permease for cytosine/purines, uracil, thiamine, allantoin Pfl_4136 34 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 77457706 Common - K+ transporter Trk Pfl_1479 163 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 77459167 Common - Molybdate ABC transporter, permease protein Pfl_2942 237 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 77458642 Common - Alpha/beta hydrolase fold Pfl_2417 169 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77457658 Common - hypothetical protein Pfl_1431 1 None None None 77460532 Common - hypothetical protein Pfl_4311 245 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 77457474 Common - inner-membrane translocator Pfl_1247 153 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 77456655 Common - hypothetical protein Pfl_0427 116 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77457264 Common - GCN5-related N-acetyltransferase Pfl_1037 8 COG3153 COG3153, Predicted acetyltransferase General function prediction only 77457976 Nonpathogen - hypothetical protein Pfl_1749 1 None None None 77460211 Common - DAHP synthetase, class II Pfl_3990 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 77460439 Common rumA 23S rRNA 5-methyluridine methyltransferase Pfl_4218 199 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 77456599 Common - Peptidase S33, proline iminopeptidase 1 Pfl_0371 127 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77456961 Common - GCN5-related N-acetyltransferase Pfl_0733 5 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 77456367 Common - ABC transporter-like Pfl_0139 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 77458456 Common - NADH:flavin oxidoreductase/NADH oxidase Pfl_2229 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77458060 Common - chemotaxis sensory transducer, Pas/Pac sensor Pfl_1833 160 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77460856 Common - Addiction module toxin, Txe/YoeB Pfl_4635 53 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 77461138 Common - GCN5-related N-acetyltransferase Pfl_4917 104 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 77458366 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_2139 123 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77456779 Common - FAD dependent oxidoreductase Pfl_0551 118 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77461140 Common - hypothetical protein Pfl_4919 132 COG2081 COG2081, Predicted flavoproteins General function prediction only 77456950 Common - Transcriptional Regulator, RpiR family Pfl_0722 91 COG1737 RpiR, Transcriptional regulators Transcription 77457469 Common - hypothetical protein Pfl_1242 63 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 77460634 Common - hypothetical protein Pfl_4413 18 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 77461680 Common - extracellular solute-binding protein, family 3 Pfl_5459 169 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77456743 Common - oligoribonuclease Pfl_0515 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 77456720 Common - thiamine biosynthesis protein ThiC Pfl_0492 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 77459154 Common - UTP--glucose-1-phosphate uridylyltransferase Pfl_2929 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 77456552 Common hisH imidazole glycerol phosphate synthase subunit HisH Pfl_0324 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 77456974 Common - Phage integrase Pfl_0747 104 COG0582 XerC, Integrase DNA replication, recombination, and repair 77458523 Common - methionine sulfoxide reductase A Pfl_2296 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 77457672 Common - hypothetical protein Pfl_1445 1 None None None 77459790 Common - Glycoside hydrolase, family 18 Pfl_3568 22 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 77458848 Common - hypothetical protein Pfl_2623 1 None None None 77456671 Common - Thioredoxin-like Pfl_0443 229 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 77459700 Nonpathogen - hypothetical protein Pfl_3478 1 None None None 77460376 Common - 3-oxoacyl-(acyl carrier protein) synthase II Pfl_4155 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77461877 Common - N-acetylmuramoyl-L-alanine amidase Pfl_5657 178 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 77457050 Common - regulatory protein GntR, HTH Pfl_0823 139 COG2186 FadR, Transcriptional regulators Transcription 77458177 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pfl_1950 69 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 77460339 Common - Electron transfer flavoprotein-ubiquinone oxidoreductase Pfl_4118 111 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 77460814 Common - Peptidase M23B Pfl_4593 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 77459517 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3295 196 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 77456995 Common greA transcription elongation factor GreA Pfl_0768 204 COG0782 GreA, Transcription elongation factor Transcription 77458967 Common - Twin-arginine translocation pathway signal Pfl_2742 42 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 77458760 Common - Alpha amylase, catalytic region Pfl_2535 172 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 77458634 Common - Predicted transcriptional regulator Pfl_2407 120 COG1733 COG1733, Predicted transcriptional regulators Transcription 77460322 Common - GCN5-related N-acetyltransferase Pfl_4101 73 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 77457139 Common - Maleylacetoacetate isomerase Pfl_0912 85 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77457989 Common - Protein of unknown function DUF785 Pfl_1762 31 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 77456417 Common - Predicted signal transduction protein Pfl_0189 207 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 77458783 Common - hypothetical protein Pfl_2558 85 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 77461655 Common - Peptidase M24 Pfl_5434 236 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 77456488 Common ompR osmolarity response regulator Pfl_0260 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77460560 Common - transmembrane pair Pfl_4339 41 COG4125 COG4125, Predicted membrane protein Function unknown 77461963 Common - hypothetical protein Pfl_2415 7 None None None 77460506 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein Pfl_4285 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 77461926 Common - hypothetical protein Pfl_5706 1 None None None 77460945 Common - malate:quinone oxidoreductase Pfl_4724 55 COG0579 COG0579, Predicted dehydrogenase General function prediction only 77461538 Common - NLP/P60 Pfl_5317 156 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 77457549 Common - Lysine exporter protein (LYSE/YGGA) Pfl_1322 28 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77458468 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pfl_2241 34 COG3565 COG3565, Predicted dioxygenase of extradiol dioxygenase family General function prediction only 77461333 Common - hypothetical protein Pfl_5112 18 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 77461222 Common - Protein of unknown function DUF1175 Pfl_5001 13 COG3234 COG3234, Uncharacterized protein conserved in bacteria Function unknown 77461258 Common - cardiolipin synthase 2 Pfl_5037 142 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 77461631 Common - Molybdenum-pterin binding protein Pfl_5410 44 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 77461210 Common - Aldehyde dehydrogenase (NAD+) Pfl_4989 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77457228 Common - hypothetical protein Pfl_1001 3 None None None 77460909 Common - ClpXP protease specificity-enhancing factor Pfl_4688 65 COG2969 SspB, Stringent starvation protein B General function prediction only 77456536 Common - hypothetical protein Pfl_0308 14 None None None 77460988 Common - General substrate transporter Pfl_4767 127 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77459267 Common - hypothetical protein Pfl_3045 2 None None None 77459699 Nonpathogen - hypothetical protein Pfl_3477 1 None None None 77461442 Common - Electron transfer flavoprotein, alpha subunit Pfl_5221 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 77460271 Nonpathogen - hypothetical protein Pfl_4050 1 None None None 77460332 Common - hypothetical protein Pfl_4111 1 None None None 77456625 Common - ATP-dependent protease peptidase subunit Pfl_0397 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 77458945 Common - General substrate transporter Pfl_2720 130 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77461280 Common secY preprotein translocase subunit SecY Pfl_5059 232 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 77458560 Nonpathogen - hypothetical protein Pfl_2333 1 None None None 77458627 Common - Transcriptional Regulator, ArsR family Pfl_2400 149 COG0640 ArsR, Predicted transcriptional regulators Transcription 77461955 Common - ParB-like partition protein Pfl_5738 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 77456891 Common - Heavy metal transport/detoxification protein Pfl_0663 50 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 77460213 Common - Protein of unknown function DUF1127 Pfl_3992 1 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 77461020 Common - transport system permease protein Pfl_4799 185 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 77460938 Common - hypothetical protein Pfl_4717 3 None None None 77460144 Common - hypothetical protein Pfl_3923 54 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 77457540 Common - Transcriptional Regulator, LysR family Pfl_1313 178 COG0583 LysR, Transcriptional regulator Transcription 77461098 Common glyA serine hydroxymethyltransferase Pfl_4877 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 77461491 Common ligB NAD-dependent DNA ligase LigB Pfl_5270 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 77461075 Common - Virulence factor MVIN-like Pfl_4854 192 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 77456514 Common - Thioesterase, putative Pfl_0286 35 None None None 77457183 Common - outer membrane protein AlgE Pfl_0956 3 None None None 77461230 Common - Periplasmic binding protein Pfl_5009 112 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 77458413 Common rnhA ribonuclease H Pfl_2186 180 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 77458309 Common - hypothetical protein Pfl_2082 14 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 77460870 Nonpathogen - hypothetical protein Pfl_4649 1 None None None 77458894 Common - regulatory protein GntR, HTH Pfl_2669 127 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 77460826 Common - Nucleoside diphosphate kinase Pfl_4605 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 77460793 Common - Transcriptional Regulator, PadR-like family Pfl_4572 59 COG1695 COG1695, Predicted transcriptional regulators Transcription 77459364 Common - Spermidine/putrescine ABC transporter ATP-binding subunit Pfl_3142 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77461233 Common - hypothetical protein Pfl_5012 8 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77460542 Common - Short-chain dehydrogenase/reductase SDR Pfl_4321 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77460931 Common - Lysine exporter protein (LYSE/YGGA) Pfl_4710 112 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77457402 Common recA recombinase A Pfl_1175 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 77460066 Common - Protein tyrosine phosphatase Pfl_3845 129 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 77459711 Nonpathogen - hypothetical protein Pfl_3489 1 None None None 77456477 Common - Transcriptional Regulator, LacI family Pfl_0249 126 COG1609 PurR, Transcriptional regulators Transcription 77460149 Common - ABC transporter-like Pfl_3928 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 77458483 Common - putative cytochrome P460 Pfl_2256 16 None None None 77461724 Common - hypothetical protein Pfl_5503 3 None None None 77457109 Common - Peptidylprolyl isomerase, FKBP-type Pfl_0882 130 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 77461661 Common - Protein of unknown function DUF589 Pfl_5440 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 77461740 Common - ATP-dependent DNA helicase RepA Pfl_5519 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 77458229 Common - Electron transport protein SCO1/SenC Pfl_2002 76 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 77459677 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Pfl_3455 42 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 77461527 Common - CheW protein Pfl_5306 100 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77459216 Common - Cobyrinic acid a,c-diamide synthase Pfl_2994 21 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77459266 Common - Fimbrial biogenesis outer membrane usher protein Pfl_3044 37 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 77457154 Common - Aspartate kinase Pfl_0927 42 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 77460840 Common secD preprotein translocase subunit SecD Pfl_4619 203 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 77457983 Common - Permease for cytosine/purines, uracil, thiamine, allantoin Pfl_1756 64 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 77461888 Common - Band 7 protein Pfl_5668 86 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 77461766 Common - Exodeoxyribonuclease III xth Pfl_5545 191 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 77458441 Common - Secretion protein HlyD Pfl_2214 166 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77460897 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase Pfl_4676 224 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 77460483 Common - hypothetical protein Pfl_4262 25 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 77458150 Common - Ribokinase Pfl_1923 198 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 77460000 Common codB cytosine permease Pfl_3778 47 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 77457232 Common - Sugar isomerase (SIS) Pfl_1005 233 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 77457517 Common - hypothetical protein Pfl_1290 1 None None None 77461178 Common leuS leucyl-tRNA synthetase Pfl_4957 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77459756 Common - NAD(P)H dehydrogenase (quinone) Pfl_3534 88 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 77460057 Common - UTP--glucose-1-phosphate uridylyltransferase Pfl_3835 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 77459715 Nonpathogen - hypothetical protein Pfl_3493 1 None None None 77459836 Common - NADH dehydrogenase subunit M Pfl_3614 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 77459963 Common - extracellular solute-binding protein, family 5 Pfl_3741 145 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 77458384 Common - hypothetical protein Pfl_2157 48 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 77461251 Common - NAD-dependent epimerase/dehydratase Pfl_5030 235 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 77460388 Common - hypothetical protein Pfl_4167 81 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 77457954 Common - hypothetical protein Pfl_1727 1 None None None 77457823 Common - 2-hydroxy-3-oxopropionate reductase Pfl_1596 163 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 77457583 Common - Predicted signal transduction protein Pfl_1356 53 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 77459473 Nonpathogen - hypothetical protein Pfl_3251 1 None None None 77458476 Common - Two Component Transcriptional Regulator, LuxR family Pfl_2249 215 COG4566 TtrR, Response regulator Signal transduction mechanisms 77457581 Common - Two component Transcriptional regulator, Winged helix family Pfl_1354 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77461208 Common - L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase Pfl_4987 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 77456620 Common - Poly(R)-hydroxyalkanoic acid synthase, class II Pfl_0392 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 77459327 Common - Acyltransferase 3 Pfl_3105 69 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 77461844 Common - hypothetical protein Pfl_5623 1 None None None 77461501 Common - S-adenosyl-L-homocysteine hydrolase Pfl_5280 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 77457424 Common - prolyl-tRNA synthetase Pfl_1197 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77457207 Common - hypothetical protein Pfl_0980 66 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 77457960 Common - hypothetical protein Pfl_1733 1 None None None 77458131 Common - oxidoreductase Pfl_1904 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77457175 Common - Insecticidal toxin protein, putative Pfl_0948 52 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 77457967 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Pfl_1740 158 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 77458216 Common - hypothetical protein Pfl_1989 76 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 77459042 Common - UDP-glucose 6-dehydrogenase Pfl_2817 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 77456679 Common - Acyl-CoA dehydrogenase-like Pfl_0451 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77458865 Common - extracellular solute-binding protein, family 1 Pfl_2640 105 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 77459101 Common pssA phosphatidylserine synthase Pfl_2876 37 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 77458015 Common - Putative RNA methylase Pfl_1788 162 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 77460681 Common - Protein of unknown function DUF347 Pfl_4460 27 COG4705 COG4705, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 77459536 Common - putative monovalent cation/H+ antiporter subunit F Pfl_3314 69 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 77459986 Common - metallothionein, putative Pfl_3764 3 None None None 77457037 Common - Oligopeptide/dipeptide ABC transporter, ATP-binding protein-like Pfl_0810 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 77458048 Common - Cbb3-type cytochrome oxidase component Pfl_1821 10 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 77456500 Common - hypothetical protein Pfl_0272 5 None None None 77458296 Common - hypothetical protein Pfl_2069 7 None None None 77461142 Common - hypothetical protein Pfl_4921 115 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77459406 Nonpathogen - hypothetical protein Pfl_3184 1 None None None 77456728 Common - hypothetical protein Pfl_0500 1 None None None 77460373 Common - Thymidylate kinase Pfl_4152 229 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 77458379 Common - Glutathione-dependent formaldehyde-activating, GFA Pfl_2152 36 COG3791 COG3791, Uncharacterized conserved protein Function unknown 77459851 Common - Alpha/beta hydrolase fold Pfl_3629 108 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77461508 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase Pfl_5287 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 77457538 Common - Iron-containing alcohol dehydrogenase Pfl_1311 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 77457791 Common - Response regulator receiver domain protein (CheY) Pfl_1564 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77459262 Common - Histidine Kinase Pfl_3040 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456935 Common - Acriflavin resistance protein Pfl_0707 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77456597 Common - Substrate-binding region of ABC-type glycine betaine transport system Pfl_0369 61 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 77457524 Common - Glycoside hydrolase, family 3-like Pfl_1297 127 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 77461260 Common - hypothetical protein Pfl_5039 6 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 77460103 Common - ABC transporter-like Pfl_3882 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 77457042 Common - extracellular solute-binding protein, family 5 Pfl_0815 210 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 77457149 Common - ribosomal subunit interface protein, putative Pfl_0922 19 None None None 77459317 Common - hypothetical protein Pfl_3095 14 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 77461291 Common rpsQ 30S ribosomal protein S17 Pfl_5070 236 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 77457226 Common - phosphoribosylformylglycinamidine synthase Pfl_0999 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 77460258 Common - Transcriptional Regulator, TetR family Pfl_4037 58 COG1309 AcrR, Transcriptional regulator Transcription 77458928 Common - Two component Transcriptional regulator, Winged helix family Pfl_2703 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77458372 Common - Molybdopterin biosynthesis MoaE Pfl_2145 158 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 77460968 Common - Modification methylase HemK Pfl_4747 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 77459079 Common - ABC transporter-like Pfl_2854 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 77457164 Common - Transcriptional Regulator, LysR family Pfl_0937 121 COG0583 LysR, Transcriptional regulator Transcription 77460444 Common - D-lactate dehydrogenase Pfl_4223 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 77456462 Nonpathogen - hypothetical protein Pfl_0234 1 None None None 77460278 Common - dTDP-4-dehydrorhamnose reductase Pfl_4057 172 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 77456686 Common - Protein of unknown function DUF519 Pfl_0458 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 77461454 Common - hypothetical protein Pfl_5233 30 COG0824 FcbC, Predicted thioesterase General function prediction only 77457971 Common - enoyl-CoA hydratase Pfl_1744 101 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77459585 Common - Peptidase M10A and M12B, matrixin and adamalysin Pfl_3363 28 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 77460022 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_3800 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 77456244 Common fmt methionyl-tRNA formyltransferase Pfl_0016 222 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 77456251 Common aroE shikimate 5-dehydrogenase Pfl_0023 217 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 77459912 Common - lipoprotein, putative Pfl_3690 13 COG5373 COG5373, Predicted membrane protein Function unknown 77460205 Common - heat shock protein HtpX Pfl_3984 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 77461865 Common - Protein of unknown function DUF6, transmembrane Pfl_5645 50 COG2510 COG2510, Predicted membrane protein Function unknown 77458078 Common - Protein of unknown function DUF323 Pfl_1851 96 COG1262 COG1262, Uncharacterized conserved protein Function unknown 77460630 Common ruvC Holliday junction resolvase Pfl_4409 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 77457683 Common - hypothetical protein Pfl_1456 3 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 77459817 Common - NUDIX hydrolase Pfl_3595 59 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 77460451 Common - hypothetical protein Pfl_4230 3 COG3308 COG3308, Predicted membrane protein Function unknown 77459489 Common - Endoribonuclease L-PSP Pfl_3267 130 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 77459469 Common - Ppx/GppA phosphatase Pfl_3247 181 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 77461089 Common - hypothetical protein Pfl_4868 1 None None None 77461784 Nonpathogen - hypothetical protein Pfl_5563 2 None None None 77457556 Nonpathogen - hypothetical protein Pfl_1329 1 None None None 77459898 Common - Serine/Threonine protein kinase Pfl_3676 60 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 77458815 Common - hypothetical protein Pfl_2590 9 None None None 77459830 Common - NADH dehydrogenase subunit G Pfl_3608 181 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 77458300 Common - NADP oxidoreductase, coenzyme F420-dependent Pfl_2073 44 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 161485593 Common - Mandelate racemase/muconate lactonizing enzyme Pfl_2325 143 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 77460348 Common - hypothetical protein Pfl_4127 3 None None None 77459935 Common aroE shikimate 5-dehydrogenase Pfl_3713 211 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 77460688 Common - Binding-protein-dependent transport systems inner membrane component Pfl_4467 226 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 77460642 Common - nucleotide-binding protein Pfl_4421 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 77459211 Common - hypothetical protein Pfl_2988 105 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 77460809 Common - inositol-5-monophosphate dehydrogenase Pfl_4588 240 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 77458728 Common - hypothetical protein Pfl_2503 4 None None None 77460760 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_4539 197 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77458356 Common - hypothetical protein Pfl_2129 2 None None None 77458903 Common - Peptidase M10A and M12B, matrixin and adamalysin Pfl_2678 87 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 77457570 Common - ABC transporter, periplasmic substrate-binding protein Pfl_1343 64 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 77457520 Common - amidase Pfl_1293 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 77459672 Common - Polysaccharide deacetylase Pfl_3450 80 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 77461093 Common - lipoprotein, putative Pfl_4872 5 None None None 77459788 Common - Methylated-DNA-(protein)-cysteine S-methyltransferase Pfl_3566 218 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 77457315 Common - succinyl-diaminopimelate desuccinylase Pfl_1088 195 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 77460089 Common - SNF2-like Pfl_3868 133 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 77460603 Common - chemotaxis sensory transducer Pfl_4382 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77460425 Common - Phenylacetic acid degradation-like protein Pfl_4204 84 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 77459591 Common - cyanate hydratase Pfl_3369 41 COG1513 CynS, Cyanate lyase Inorganic ion transport and metabolism 77460979 Common - chemotaxis sensory transducer Pfl_4758 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77461117 Common - hypothetical protein Pfl_4896 3 None None None 77458749 Common - RND efflux system, outer membrane lipoprotein, NodT Pfl_2524 113 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77460417 Common - orotidine 5'-phosphate decarboxylase Pfl_4196 170 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 77457996 Common - hypothetical protein Pfl_1769 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 77458220 Common - Curli production assembly/transport component CsgG Pfl_1993 17 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 77460975 Common - 50S ribosomal protein L25/general stress protein Ctc Pfl_4754 186 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 77459598 Common - hypothetical protein Pfl_3376 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 77460456 Common - Alpha-methylacyl-CoA racemase Pfl_4235 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 77458406 Common - Binding-protein-dependent transport systems inner membrane component Pfl_2179 221 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 77457311 Common - glycerol-3-phosphate acyltransferase Pfl_1084 48 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 77459567 Common - Transcriptional Regulator, Crp/Fnr family Pfl_3345 148 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 77461396 Common - 8-amino-7-oxononanoate synthase Pfl_5175 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 77457887 Common - Periplasmic Sensor Hybrid Histidine Kinase Pfl_1660 219 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 77460091 Common - beta-hexosaminidase Pfl_3870 182 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 77459545 Nonpathogen - hypothetical protein Pfl_3323 1 None None None 77456387 Nonpathogen - hypothetical protein Pfl_0159 1 None None None 77458563 Common - ABC transporter-like Pfl_2336 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 77461893 Common - Lysine exporter protein (LYSE/YGGA) Pfl_5673 25 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 77461870 Common - pyridoxamine kinase Pfl_5650 60 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 77458733 Common - hypothetical protein Pfl_2508 3 None None None 77458665 Common - Paraquat-inducible protein A Pfl_2440 53 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 77459847 Common - Heavy Metal Sensor Signal Transduction Histidine Kinases (STHK) Pfl_3625 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77460534 Common - hypothetical protein Pfl_4313 1 None None None 77458094 Common - Cyclic nucleotide-regulated Small Mechanosensitive ion channel Pfl_1867 194 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77460338 Common - Electron transfer flavoprotein beta-subunit Pfl_4117 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 77460478 Common - hypothetical protein Pfl_4257 2 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 77456610 Common tatA twin argininte translocase protein A Pfl_0382 16 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 77461263 Common - Isochorismatase hydrolase Pfl_5042 104 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 77457006 Common infB translation initiation factor IF-2 Pfl_0779 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 77456531 Nonpathogen - hypothetical protein Pfl_0303 1 None None None 77457809 Common - Cytochrome c-type biogenesis protein CcmF Pfl_1582 122 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 77456585 Common - N-formimino-L-glutamate deiminase Pfl_0357 126 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 77459930 Common - Major facilitator superfamily MFS_1 Pfl_3708 193 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461198 Common - hypothetical protein Pfl_4977 9 None None None 77457615 Common - Ribonuclease D Pfl_1388 115 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 77456324 Common - Protein of unknown function DUF1161 Pfl_0096 1 None None None 77458325 Common - hypothetical protein Pfl_2098 7 None None None 77457644 Common - Protein of unknown function DUF6, transmembrane Pfl_1417 73 COG2962 RarD, Predicted permeases General function prediction only 77457366 Common - Phage baseplate assembly protein V Pfl_1139 9 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 77461717 Common cyaY frataxin-like protein Pfl_5496 42 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 77456882 Common - MaoC-like dehydratase Pfl_0654 29 COG2030 MaoC, Acyl dehydratase Lipid metabolism 77459012 Common - Zinc transporter ZIP Pfl_2787 107 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 77459440 Common - Glutathione S-transferase-like Pfl_3218 47 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77459124 Nonpathogen - hypothetical protein Pfl_2899 1 None None None 77457643 Common - Protein of unknown function DUF6, transmembrane Pfl_1416 32 None None None 77456490 Common - S6 modification enzyme RimK Pfl_0262 153 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 77460121 Common - hypothetical protein Pfl_3900 95 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 77459447 Common - hypothetical protein Pfl_3225 15 COG3802 GguC, Uncharacterized protein conserved in bacteria Function unknown 77459480 Common - Dyp-type peroxidase Pfl_3258 56 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 77459052 Common - Transcriptional Regulator, AraC family Pfl_2827 53 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77459179 Common - Beta-lactamase-like Pfl_2954 34 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 77458319 Common - UbiE/COQ5 methyltransferase Pfl_2092 94 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77460224 Common cysB transcriptional regulator CysB Pfl_4003 189 COG0583 LysR, Transcriptional regulator Transcription 77457767 Common fliJ flagellar biosynthesis chaperone Pfl_1540 40 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 77459860 Common cysS cysteinyl-tRNA synthetase Pfl_3638 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77460917 Common - Acyl-CoA dehydrogenase-like Pfl_4696 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77456291 Common - lipoprotein, putative Pfl_0063 1 None None None 77457394 Common - hypothetical protein Pfl_1167 12 None None None 77460659 Common sbcB exonuclease I Pfl_4438 52 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 77461436 Common - Oxidoreductase FAD-binding region Pfl_5215 161 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 77458572 Common - hypothetical protein Pfl_2345 1 None None None 77457760 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Pfl_1533 198 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77457812 Common - Cytochrome c-type biogenesis protein Pfl_1585 58 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 77460567 Common - hypothetical protein Pfl_4346 11 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 77458052 Common - cytochrome c oxidase, cbb3-type, CcoQ subunit Pfl_1825 3 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 77457111 Common - NADH:flavin oxidoreductase/NADH oxidase Pfl_0884 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 77461944 Common - Transcriptional Regulator, DeoR family Pfl_5727 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 77461536 Common pyrC dihydroorotase Pfl_5315 207 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 77458705 Common - Transcriptional Regulator, TetR family Pfl_2480 63 COG1309 AcrR, Transcriptional regulator Transcription 77459555 Common - hypothetical protein Pfl_3333 3 None None None 77456247 Common - SMF protein Pfl_0019 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 77456782 Common - inner-membrane translocator Pfl_0554 153 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 77458769 Common - Glycogen debranching enzyme GlgX Pfl_2544 151 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 77460785 Common - hypothetical protein Pfl_4564 15 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 77460262 Common - Competence protein ComEA helix-hairpin-helix region Pfl_4041 94 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 77456433 Common - hypothetical protein Pfl_0205 59 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 77459573 Common - Possible Transcriptional activator, TenA family Pfl_3351 24 COG0819 TenA, Putative transcription activator Transcription 77461463 Common - transcriptional regulator BetI Pfl_5242 53 COG1309 AcrR, Transcriptional regulator Transcription 77459454 Common - Alpha/beta hydrolase fold Pfl_3232 177 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77459171 Nonpathogen - hypothetical protein Pfl_2946 1 None None None 77459460 Common - hypothetical protein Pfl_3238 3 None None None 77461042 Common - type II secretion system protein Pfl_4821 147 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 77457657 Common - Transcriptional Regulator, LysR family Pfl_1430 142 COG0583 LysR, Transcriptional regulator Transcription 77457379 Common - hypothetical protein Pfl_1152 6 None None None 77458274 Common - Alpha/beta hydrolase fold Pfl_2047 166 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77461759 Common - extracellular solute-binding protein, family 5 Pfl_5538 196 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 77461191 Common - Penicillin-binding protein, transpeptidase Pfl_4970 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 77456811 Common - GCN5-related N-acetyltransferase Pfl_0583 124 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 77456702 Common - Glycosyl transferase, group 1 Pfl_0474 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77459945 Common ampC beta-lactamase Pfl_3723 108 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 77459873 Common - Acyl-CoA dehydrogenase-like Pfl_3651 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77456694 Common - Lipopolysaccharide heptosyltransferase I Pfl_0466 95 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 77457309 Common - hypothetical protein Pfl_1082 26 None None None 77459286 Common - Phage integrase Pfl_3064 100 COG0582 XerC, Integrase DNA replication, recombination, and repair 77461314 Common tuf elongation factor Tu Pfl_5093 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 77459017 Common - hypothetical protein Pfl_2792 10 None None None 77459098 Common - hypothetical protein Pfl_2873 27 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 77458278 Nonpathogen - hypothetical protein Pfl_2051 1 None None None 77460304 Common - short chain dehydrogenase Pfl_4083 177 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77456453 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_0225 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77459614 Common - tRNA--hydroxylase Pfl_3392 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 77459829 Common - NADH dehydrogenase I subunit F Pfl_3607 171 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 77456273 Nonpathogen - hypothetical protein Pfl_0045 1 None None None 77457239 Common - Protein of unknown function DUF1289 Pfl_1012 43 COG3313 COG3313, Predicted Fe-S protein General function prediction only 77460753 Common glpK glycerol kinase Pfl_4532 177 COG0554 GlpK, Glycerol kinase Energy production and conversion 77457356 Common surE stationary phase survival protein SurE Pfl_1129 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 77458083 Common - hypothetical protein Pfl_1856 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 77457250 Common - Thioesterase superfamily Pfl_1023 131 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 77456923 Common - Methylmalonate-semialdehyde dehydrogenase Pfl_0695 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77459692 Common - Short-chain dehydrogenase/reductase SDR Pfl_3470 147 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 77461613 Common - hypothetical protein Pfl_5392 3 None None None 77461574 Common - Peptidase C56, PfpI Pfl_5353 164 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 77456346 Common - L-carnitine dehydratase/bile acid-inducible protein F Pfl_0118 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 77459974 Common - Glutathione S-transferase-like Pfl_3752 101 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77461108 Common mscL large-conductance mechanosensitive channel Pfl_4887 143 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77457773 Common fliM flagellar motor switch protein FliM Pfl_1546 112 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 77460248 Common - Patatin Pfl_4027 126 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 77456352 Common - chemotaxis sensory transducer, Cache sensor Pfl_0124 156 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77460527 Common - Transcriptional Regulator, TetR family Pfl_4306 146 COG1309 AcrR, Transcriptional regulator Transcription 77459940 Common - Peptidase U32 Pfl_3718 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 77461653 Common - hypothetical protein Pfl_5432 18 None None None 77456909 Common - ABC transporter-like Pfl_0681 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 77459728 Nonpathogen - hypothetical protein Pfl_3506 1 None None None 77458947 Common - Transcriptional Regulator, LysR family Pfl_2722 161 COG0583 LysR, Transcriptional regulator Transcription 77456754 Common - HflC Pfl_0526 181 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 77459140 Common - Aldo/keto reductase Pfl_2915 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 77456400 Common - Protein of unknown function DUF1656 Pfl_0172 11 None None None 77458724 Common - Biopolymer transport protein ExbD/TolR Pfl_2499 119 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 77459376 Common - Amidohydrolase-like Pfl_3154 113 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 77460500 Common - succinylglutamate desuccinylase Pfl_4279 24 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 77459754 Common - extracellular solute-binding protein, family 1 Pfl_3532 127 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77458248 Common - Polysaccharide export protein Pfl_2021 94 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 77459524 Common - hypothetical protein Pfl_3302 44 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 77458494 Common - Amino acid adenylation Pfl_2267 236 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77458022 Common - Protein of unknown function DUF182 Pfl_1795 78 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 77461002 Common - Paraquat-inducible protein A Pfl_4781 56 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 77461292 Common - 50S ribosomal protein L29 Pfl_5071 140 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 77460669 Common - pyruvate kinase Pfl_4448 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 77458241 Nonpathogen - Membrane protein involved in the export of O-antigen and teichoic acid-like Pfl_2014 2 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 77458459 Common - TonB-dependent siderophore receptor Pfl_2232 114 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 77459237 Common - Plasmid conserved hypothetical protein, RAQPRD Pfl_3015 16 None None None 77457598 Common dapA dihydrodipicolinate synthase Pfl_1371 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 77457663 Common - MscS Mechanosensitive ion channel Pfl_1436 60 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77460910 Common - Glutathione S-transferase-like Pfl_4689 105 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77457148 Common - Transcriptional Regulator, LysR family Pfl_0921 171 COG0583 LysR, Transcriptional regulator Transcription 77461323 Common argC N-acetyl-gamma-glutamyl-phosphate reductase Pfl_5102 213 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 77458163 Common pheT phenylalanyl-tRNA synthetase subunit beta Pfl_1936 248 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 77458474 Common - Transcriptional Regulator, LuxR family Pfl_2247 65 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 77459412 Common - ATPase domain protein Pfl_3190 82 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 77456481 Common tauD taurine dioxygenase Pfl_0253 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 77456769 Common - Transglutaminase-like Pfl_0541 83 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 77461940 Common - Tn7-like transposition protein C Pfl_5723 18 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 77459465 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3243 209 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 77457988 Common - hypothetical protein Pfl_1761 19 None None None 77456947 Common - Transcriptional Regulator, LysR family Pfl_0719 187 COG0583 LysR, Transcriptional regulator Transcription 77458045 Common - 4Fe-4S ferredoxin, iron-sulfur binding Pfl_1818 77 COG0348 NapH, Polyferredoxin Energy production and conversion 77460964 Common - hypothetical protein Pfl_4743 11 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 77458819 Common - hypothetical protein Pfl_2594 2 None None None 77459066 Common - UDP-4-amino-4-deoxy-L-arabinose--oxoglutarate aminotransferase Pfl_2841 212 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 77457296 Common - phosphoenolpyruvate carboxylase Pfl_1069 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 77459434 Common - hypothetical protein Pfl_3212 49 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 77460064 Common - Glycosyl transferase, group 1 Pfl_3843 223 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77458027 Common zipA cell division protein ZipA Pfl_1800 44 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 77458262 Common - hypothetical protein Pfl_2035 2 None None None 77459138 Common - Short-chain dehydrogenase/reductase SDR Pfl_2913 33 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77461276 Common - DNA-directed RNA polymerase subunit alpha Pfl_5055 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 77461687 Common - DedA Pfl_5466 69 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 77458875 Common - Response regulator receiver domain protein (CheY) Pfl_2650 176 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77457655 Common - Peptidyl-prolyl cis-trans isomerase, cyclophilin type Pfl_1428 197 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 77459100 Common - Protein of unknown function DUF451 Pfl_2875 28 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 77461670 Common - TonB-like Pfl_5449 7 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 77461564 Common - 3-mercaptopyruvate sulfurtransferase Pfl_5343 142 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 77456698 Common - Lipopolysaccharide kinase Pfl_0470 8 None None None 77460012 Common - hypothetical protein Pfl_3790 45 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 77460209 Common - enoyl-CoA hydratase Pfl_3988 170 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77460798 Common - Pyrrolo-quinoline quinone Pfl_4577 59 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 77459920 Common tig trigger factor Pfl_3698 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 77460984 Common - hypothetical protein Pfl_4763 15 None None None 77459152 Common - cointegrate resolution protein T Pfl_2927 19 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 77461649 Common gcvT glycine cleavage system aminomethyltransferase T Pfl_5428 180 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 77458988 Common - hypothetical protein Pfl_2763 2 None None None 77457168 Common - Secretion protein HlyD Pfl_0941 105 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77461063 Common - hypothetical protein Pfl_4842 18 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 77461348 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Pfl_5127 180 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 77459107 Common - enoyl-CoA hydratase Pfl_2882 181 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 77461543 Common - hypothetical protein Pfl_5322 71 COG1872 COG1872, Uncharacterized conserved protein Function unknown 77458099 Nonpathogen - hypothetical protein Pfl_1872 1 None None None 77460362 Common - Periplasmic binding protein/LacI transcriptional regulator Pfl_4141 29 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 77458696 Common - Cytochrome c, class I Pfl_2471 72 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 77459037 Common - NusG antitermination factor Pfl_2812 105 COG0250 NusG, Transcription antiterminator Transcription 77458076 Common - Amino acid adenylation Pfl_1849 222 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77458219 Common - curli fiber protein CsgF, putative Pfl_1992 13 None None None 77459740 Common - hypothetical protein Pfl_3518 4 None None None 77457325 Common - hypothetical protein Pfl_1098 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 77460861 Common - hypothetical protein Pfl_4640 8 None None None 77456895 Common - Antibiotic biosynthesis monooxygenase Pfl_0667 44 COG1359 COG1359, Uncharacterized conserved protein Function unknown 77457483 Common - hypothetical protein Pfl_1256 1 None None None 77456234 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_0006 220 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 77459864 Common - Drug resistance transporter EmrB/QacA subfamily Pfl_3642 198 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77461805 Common - ClpB protein, putative Pfl_5584 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 77459649 Common - Transcriptional Regulator, LysR family Pfl_3427 89 COG0583 LysR, Transcriptional regulator Transcription 77457155 Common - hypothetical protein Pfl_0928 5 None None None 77459192 Common - Aromatic-ring-hydroxylating dioxygenase, beta subunit Pfl_2967 26 COG5517 COG5517, Small subunit of phenylpropionate dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 77460744 Common - Bacterioferritin Pfl_4523 101 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 77461730 Nonpathogen - hypothetical protein Pfl_5509 1 None None None 77459814 Common - Cold shock protein cspD Pfl_3592 167 COG1278 CspC, Cold shock proteins Transcription 77456550 Common - Major facilitator superfamily MFS_1 Pfl_0322 74 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 77458224 Common - Curlin associated Pfl_1997 18 None None None 77461737 Common - Transcriptional Regulator, LysR family Pfl_5516 166 COG0583 LysR, Transcriptional regulator Transcription 77461011 Common - Protein of unknown function DUF446 Pfl_4790 32 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 77456993 Common - carbamoyl phosphate synthase small subunit Pfl_0766 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 77457333 Common - Phosphatidate cytidylyltransferase Pfl_1106 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 77460716 Common - Lipopolysaccharide kinase Pfl_4495 7 None None None 77457908 Common - HAD-superfamily subfamily IB, PSPase-like Pfl_1681 84 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 77458605 Common - Helix-turn-helix, AraC type Pfl_2378 114 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77461085 Common - Peptidylprolyl isomerase, FKBP-type Pfl_4864 140 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 77461476 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) and Response Regulator Receiver modulation Pfl_5255 211 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 77459776 Common - Protein of unknown function DUF6, transmembrane Pfl_3554 94 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77461352 Common - Aminoglycoside phosphotransferase Pfl_5131 91 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 77460695 Common - Beta-lactamase-like Pfl_4474 35 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77457794 Common - chemotaxis-specific methylesterase Pfl_1567 211 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 77460613 Common - glycine dehydrogenase Pfl_4392 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 77458479 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_2252 177 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77459041 Common - sugar transferase Pfl_2816 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 77459923 Nonpathogen - hypothetical protein Pfl_3701 1 None None None 77461666 Common - Zinc-containing alcohol dehydrogenase superfamily Pfl_5445 159 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 77461838 Common - Thioesterase superfamily Pfl_5617 128 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 77460558 Common - Transcriptional Regulator, LacI family Pfl_4337 125 COG1609 PurR, Transcriptional regulators Transcription 77457902 Common - hypothetical protein Pfl_1675 2 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 77461248 Common - Protein of unknown function DUF214 Pfl_5027 41 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 77461682 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_5461 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77458344 Common - extracellular solute-binding protein, family 1 Pfl_2117 130 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77459761 Common - hypothetical protein Pfl_3539 2 None None None 77459620 Nonpathogen - hypothetical protein Pfl_3398 1 None None None 77458852 Common - hypothetical protein Pfl_2627 11 None None None 77460996 Common - Ribosomal-protein-alanine acetyltransferase Pfl_4775 199 COG0456 RimI, Acetyltransferases General function prediction only 77461600 Common - HAD-superfamily subfamily IB, PSPase-like Pfl_5379 86 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 77460878 Common - hypothetical protein Pfl_4657 2 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 77459029 Common - Transcriptional Regulator, LysR family Pfl_2804 144 COG0583 LysR, Transcriptional regulator Transcription 77456557 Nonpathogen - hypothetical protein Pfl_0329 3 None None None 77459186 Common - Intradiol ring-cleavage dioxygenase Pfl_2961 43 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 77457304 Common - Protein of unknown function DUF548 Pfl_1077 51 None None None 77458742 Common - hypothetical protein Pfl_2517 2 None None None 77459256 Common - hypothetical protein Pfl_3034 28 None None None 77461163 Common - AMP nucleosidase Pfl_4942 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 77458432 Common - ABC transporter, periplasmic substrate-binding protein Pfl_2205 26 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 77460466 Common - Two component Transcriptional regulator, Winged helix family Pfl_4245 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77457187 Common - UDP-glucose/GDP-mannose dehydrogenase Pfl_0960 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 77459825 Common - NADH dehydrogenase subunit A Pfl_3603 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 77456336 Common - hypothetical protein Pfl_0108 1 None None None 77457266 Nonpathogen - hypothetical protein Pfl_1039 1 None None None 77457677 Common - Transcriptional Regulator, LysR family Pfl_1450 188 COG0583 LysR, Transcriptional regulator Transcription 77460294 Common cmk cytidylate kinase Pfl_4073 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 77456520 Common - hypothetical protein Pfl_0292 1 None None None 77461607 Common - FAD linked oxidase-like Pfl_5386 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 77457123 Common - Possible Sensor with PAS/PAC domain Pfl_0896 98 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 77458891 Common - Transcriptional Regulator, LysR family Pfl_2666 103 COG0583 LysR, Transcriptional regulator Transcription 77461337 Common - hypothetical protein Pfl_5116 1 None None None 77460221 Common - hypothetical protein Pfl_4000 23 COG4394 COG4394, Uncharacterized protein conserved in bacteria Function unknown 77456635 Common - Pilus assembly protein, PilO Pfl_0407 47 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 77456706 Common - Glycosyl transferase, family 2 Pfl_0478 185 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 77461050 Common - MOSC Pfl_4829 29 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 77461369 Common dnaG DNA primase Pfl_5148 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 77459252 Common - hypothetical protein Pfl_3030 2 None None None 77461059 Common - hypothetical protein Pfl_4838 4 None None None 77457434 Common - Succinylglutamate desuccinylase/aspartoacylase Pfl_1207 23 COG3608 COG3608, Predicted deacylase General function prediction only 77457358 Common - Peptidase M23B Pfl_1131 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 77460033 Common - Copper resistance B precursor Pfl_3811 43 COG3667 PcoB, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 77456258 Common - Glutathione-dependent formaldehyde-activating, GFA Pfl_0030 65 COG3791 COG3791, Uncharacterized conserved protein Function unknown 77461096 Common - putative ABC transporter ATP-binding protein Pfl_4875 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 77458621 Common - heavy metal RND efflux outer membrane protein, CzcC family Pfl_2394 50 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77460404 Common - hypothetical protein Pfl_4183 15 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 77458596 Common - Transcriptional Regulator, LysR family Pfl_2369 173 COG0583 LysR, Transcriptional regulator Transcription 77458269 Common - Rhs family protein Pfl_2042 74 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 77457840 Common sdhB succinate dehydrogenase iron-sulfur subunit Pfl_1613 207 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 77459655 Common - Xanthine/uracil permease Pfl_3433 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 77457847 Common - Protein of unknown function DUF599 Pfl_1620 27 COG3821 COG3821, Predicted membrane protein Function unknown 77458354 Nonpathogen - hypothetical protein Pfl_2127 1 None None None 77456529 Common - DSBA oxidoreductase Pfl_0301 83 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 77460382 Common - Protein of unknown function DUF177 Pfl_4161 38 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 77460704 Common - chromosome replication initiation inhibitor protein Pfl_4483 99 COG0583 LysR, Transcriptional regulator Transcription 77459768 Nonpathogen - hypothetical protein Pfl_3546 1 None None None 77456850 Common - chemotaxis sensory transducer Pfl_0622 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77456617 Common - Poly granule associated Pfl_0389 18 None None None 77458938 Common - Transcriptional Regulator, LysR family Pfl_2713 138 COG0583 LysR, Transcriptional regulator Transcription 77459243 Common - hypothetical protein Pfl_3021 21 None None None 77458533 Common - Aldehyde dehydrogenase Pfl_2306 196 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77456491 Common - Protein of unknown function DUF785 Pfl_0263 39 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 77457494 Common - Coenzyme A transferase Pfl_1267 49 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 77456413 Common - hypothetical protein Pfl_0185 1 None None None 77458090 Common - Two Component Transcriptional Regulator, LuxR family Pfl_1863 190 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77457577 Common - Putative ammonia monooxygenase Pfl_1350 50 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 77461341 Common - ribulose-phosphate 3-epimerase Pfl_5120 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 77457056 Common - D-galactonate transporter Pfl_0829 203 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77457820 Common - Urea transporter Pfl_1593 6 COG4413 Utp, Urea transporter Amino acid transport and metabolism 77460190 Common - Vesicle-fusing ATPase Pfl_3969 27 COG4575 ElaB, Uncharacterized conserved protein Function unknown 77461902 Common - GDP-mannose 4,6-dehydratase Pfl_5682 216 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 77460148 Common - Periplasmic solute binding protein Pfl_3927 173 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 77457692 Nonpathogen - hypothetical protein Pfl_1465 1 None None None 77459116 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_2891 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77459484 Common - Flavin reductase-like, FMN-binding Pfl_3262 117 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 77461937 Common - OsmC-like protein Pfl_5720 87 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 77459419 Common - Putative FecR Pfl_3197 42 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77459390 Common - hypothetical protein Pfl_3168 27 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 77457728 Common flgF flagellar basal body rod protein FlgF Pfl_1501 121 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 77460454 Common - Protein of unknown function DUF1282 Pfl_4233 24 None None None 77461357 Common apaG ApaG Pfl_5136 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 77460197 Common - Metal dependent phosphohydrolase, HD region Pfl_3976 108 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 77461698 Common - hypothetical protein Pfl_5477 13 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 77456859 Common - hypothetical protein Pfl_0631 3 None None None 77457836 Common gltA type II citrate synthase Pfl_1609 194 COG0372 GltA, Citrate synthase Energy production and conversion 77460572 Common - CsbD-like Pfl_4351 34 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 77461905 Common - ABC transporter-like Pfl_5685 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 77456601 Common mdoG glucan biosynthesis protein G Pfl_0373 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 77457817 Common - hypothetical protein Pfl_1590 10 None None None 77461282 Common rpmD 50S ribosomal protein L30 Pfl_5061 97 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 77457201 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_0974 171 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77460919 Common - AFG1-like ATPase Pfl_4698 103 COG1485 COG1485, Predicted ATPase General function prediction only 77456927 Common - hypothetical protein Pfl_0699 1 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 77456612 Common hisI phosphoribosyl-AMP cyclohydrolase Pfl_0384 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 77458836 Nonpathogen - hypothetical protein Pfl_2611 1 COG4475 COG4475, Uncharacterized protein conserved in bacteria Function unknown 77461211 Common - Amino acid permease-associated region Pfl_4990 128 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 77458954 Common - Xanthine/uracil permease Pfl_2729 129 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 77457664 Common - DEAD/DEAH box helicase-like Pfl_1437 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 77458878 Common - Possible circadian clock protein KaiC Pfl_2653 86 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 77457150 Common - TonB-dependent siderophore receptor Pfl_0923 100 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 77461707 Common - uroporphyrinogen-III synthase Pfl_5486 58 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 77461758 Common rpmB 50S ribosomal protein L28 Pfl_5537 169 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 77460755 Common glpD glycerol-3-phosphate dehydrogenase Pfl_4534 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 77461851 Common - Histone deacetylase superfamily Pfl_5631 161 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 77461881 Common - Periplasmic solute binding protein Pfl_5661 171 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 77461071 Common - Peptidylprolyl isomerase, FKBP-type Pfl_4850 133 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 77458359 Common - hypothetical protein Pfl_2132 2 None None None 77457442 Common - Isochorismatase hydrolase Pfl_1215 104 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 77458255 Common - hypothetical protein Pfl_2028 50 COG5621 COG5621, Predicted secreted hydrolase General function prediction only 77459320 Common cobN cobaltochelatase Pfl_3098 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 77456872 Common - type II secretion system protein Pfl_0644 14 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 77456772 Nonpathogen - hypothetical protein Pfl_0544 1 None None None 77461895 Common - hypothetical protein Pfl_5675 6 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 77461389 Common - Putative diguanylate cyclase (GGDEF domain) Pfl_5168 160 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 77461390 Common - hypothetical protein Pfl_5169 61 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 77458067 Common - Short-chain dehydrogenase/reductase SDR Pfl_1840 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77458711 Common - Lipopolysaccharide kinase Pfl_2486 7 None None None 77458569 Common - TonB-dependent receptor Pfl_2342 103 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 77459005 Common - Substrate-binding region of ABC-type glycine betaine transport system Pfl_2780 77 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 77461183 Common - Peptidase U61, LD-carboxypeptidase A Pfl_4962 87 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 77457746 Common - DegT/DnrJ/EryC1/StrS aminotransferase Pfl_1519 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 77457856 Common - Amidohydrolase 2 Pfl_1629 9 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 77459308 Common - hypothetical protein Pfl_3086 60 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 77460217 Common - Transcriptional Regulator, MarR family Pfl_3996 119 COG1846 MarR, Transcriptional regulators Transcription 77457711 Common - hypothetical protein Pfl_1484 1 None None None 77456465 Common - NLPA lipoprotein Pfl_0237 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 77458820 Common - Peptidase C39, bacteriocin processing Pfl_2595 42 COG3271 COG3271, Predicted double-glycine peptidase General function prediction only 77457096 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Pfl_0869 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 77461360 Common - Putative Serine protein kinase, PrkA Pfl_5139 69 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 77459289 Common - Two Component Transcriptional Regulator, LuxR family Pfl_3067 210 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77461620 Common - Transcriptional Regulator, AraC family Pfl_5399 148 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77456426 Common - Protein of unknown function DUF962 Pfl_0198 27 COG4539 COG4539, Predicted membrane protein Function unknown 77460175 Common - CheW protein Pfl_3954 159 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 77459095 Common - AMP-dependent synthetase and ligase Pfl_2870 221 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 77460059 Common - Acyltransferase 3 Pfl_3838 15 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 77461033 Common panC pantoate--beta-alanine ligase Pfl_4812 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 77460807 Common - hypothetical protein Pfl_4586 3 None None None 77456483 Common tauB taurine transporter ATP-binding subunit Pfl_0255 249 COG4525 TauB, ABC-type taurine transport system, ATPase component Inorganic ion transport and metabolism 77457364 Common - pyocin R2_PP, holin Pfl_1137 1 None None None 77456564 Common - preprotein translocase subunit SecB Pfl_0336 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 77458553 Common - Muconolactone delta-isomerase Pfl_2326 23 COG4829 CatC1, Muconolactone delta-isomerase Secondary metabolites biosynthesis, transport, and catabolism 77460351 Common - GCN5-related N-acetyltransferase Pfl_4130 89 COG0456 RimI, Acetyltransferases General function prediction only 77460583 Common - 6-phosphogluconolactonase Pfl_4362 122 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 77460839 Common secF preprotein translocase subunit SecF Pfl_4618 202 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 77459644 Common - hypothetical protein Pfl_3422 1 None None None 77461771 Common rpoZ DNA-directed RNA polymerase subunit omega Pfl_5550 116 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 77458305 Common - Silent information regulator protein Sir2 Pfl_2078 150 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 77460481 Common - Histidine Kinase Pfl_4260 144 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456827 Common - hypothetical protein Pfl_0599 3 None None None 77460858 Common - Transcriptional Regulator, LysR family Pfl_4637 137 COG0583 LysR, Transcriptional regulator Transcription 77456826 Common - Protein of unknown function DUF461 Pfl_0598 74 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 77457351 Common - Transcriptional Regulator, LysR family Pfl_1124 174 COG0583 LysR, Transcriptional regulator Transcription 77457978 Common - Rhs family protein Pfl_1751 75 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 77457030 Common - Glycine betaine/L-proline transport ATP-binding subunit Pfl_0803 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 77457044 Nonpathogen - hypothetical protein Pfl_0817 1 None None None 77456860 Common - hypothetical protein Pfl_0632 39 COG1694 MazG, Predicted pyrophosphatase General function prediction only 77457460 Common - hypothetical protein Pfl_1233 7 None None None 77460202 Common - Glutathione peroxidase Pfl_3981 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 77460112 Common - Aminoglycoside/hydroxyurea antibiotic resistance kinase Pfl_3891 29 COG3570 StrB, Streptomycin 6-kinase Defense mechanisms 77461080 Common rpmA 50S ribosomal protein L27 Pfl_4859 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 77458970 Common - AMP-dependent synthetase and ligase Pfl_2745 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77461447 Common - Protein of unknown function DUF1311 Pfl_5226 3 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 77457476 Common - hypothetical protein Pfl_1249 13 COG5626 COG5626, Uncharacterized small conserved protein Function unknown 77460738 Common - argininosuccinate synthase Pfl_4517 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 77461677 Common rho transcription termination factor Rho Pfl_5456 208 COG1158 Rho, Transcription termination factor Transcription 77458738 Common - Nitrite and sulphite reductase 4Fe-4S region Pfl_2513 162 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 77458381 Common - Porphyromonas-type peptidyl-arginine deiminase Pfl_2154 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 77460011 Nonpathogen - hypothetical protein Pfl_3789 1 None None None 77460903 Common - hypothetical protein Pfl_4682 136 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 77457862 Common - hypothetical protein Pfl_1635 187 COG0628 PerM, Predicted permease General function prediction only 77458190 Nonpathogen - hypothetical protein Pfl_1963 1 None None None 77458603 Common - Fe2+-dicitrate sensor membrane component-like Pfl_2376 4 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77457396 Common - hypothetical protein Pfl_1169 1 None None None 77458753 Common - Kelch repeat Pfl_2528 17 None None None 77456962 Nonpathogen - hypothetical protein Pfl_0734 1 None None None 77457508 Common - Transcriptional Regulator, TetR family Pfl_1281 132 COG1309 AcrR, Transcriptional regulator Transcription 77456653 Common - 3-oxoacyl-(acyl carrier protein) synthase I Pfl_0425 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77456369 Common - Transcriptional Regulator, LysR family Pfl_0141 97 COG0583 LysR, Transcriptional regulator Transcription 77456434 Common - Transcriptional Regulator, AraC family Pfl_0206 64 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77459910 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Pfl_3688 12 COG0388 COG0388, Predicted amidohydrolase General function prediction only 77459282 Common - hypothetical protein Pfl_3060 33 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 77456734 Common - Phosphoserine phosphatase SerB Pfl_0506 162 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 77457708 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_1481 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77456449 Common - Protein of unknown function DUF1234 Pfl_0221 52 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 77459161 Common - hypothetical protein Pfl_2936 24 COG3826 COG3826, Uncharacterized protein conserved in bacteria Function unknown 77461626 Common - extracellular solute-binding protein, family 1 Pfl_5405 130 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 77458744 Common - DGPFAETKE Pfl_2519 46 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 77459792 Common - Hemerythrin HHE cation binding region Pfl_3570 16 None None None 77456849 Common dipZ thiol:disulfide interchange protein precursor Pfl_0621 73 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 77457026 Common - putative hydroxylase Pfl_0799 44 COG3128 PiuC, Uncharacterized iron-regulated protein Function unknown 77456254 Common - Sulfatase Pfl_0026 98 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 77456262 Common - Na/Pi cotransporter II-like Pfl_0034 75 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 77459334 Common - Nitrite and sulphite reductase 4Fe-4S region Pfl_3112 140 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 77456834 Common - precorrin-2 C(20)-methyltransferase Pfl_0606 162 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 77460233 Common - ErfK/YbiS/YcfS/YnhG Pfl_4012 90 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 77457896 Common - hypothetical protein Pfl_1669 21 COG0753 KatE, Catalase Inorganic ion transport and metabolism 77457924 Common - Patatin Pfl_1697 86 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 77460324 Common - hypothetical protein Pfl_4103 23 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 77457605 Common - hypothetical protein Pfl_1378 8 COG3422 COG3422, Uncharacterized conserved protein Function unknown 77459629 Common - Protein of unknown function DUF877 Pfl_3407 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 77459681 Common - regulatory protein, ArsR Pfl_3459 118 COG0640 ArsR, Predicted transcriptional regulators Transcription 77459313 Common - Amino acid ABC transporter, permease protein, 3-TM region, His/Glu/Gln/Arg/opine Pfl_3091 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 77460596 Common - phosphogluconate dehydratase Pfl_4375 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 77460234 Common - hypothetical protein Pfl_4013 1 None None None 77459805 Common - Camphor resistance CrcB protein Pfl_3583 183 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 77456348 Common - PepSY-associated TM helix Pfl_0120 44 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 77458999 Common - Mandelate racemase/muconate lactonizing enzyme Pfl_2774 101 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 77457216 Common pepA leucyl aminopeptidase Pfl_0989 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 77461712 Common - hypothetical protein Pfl_5491 6 None None None 77457385 Common - DNA circulation-like Pfl_1158 21 COG4228 COG4228, Mu-like prophage DNA circulation protein General function prediction only 77457754 Common - flagellin Pfl_1527 118 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 77457878 Common - Transcriptional Regulator, MarR family Pfl_1651 33 COG1846 MarR, Transcriptional regulators Transcription 77461150 Common - ABC transporter-like Pfl_4929 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 77457699 Common - SelT/selW/selH selenoprotein Pfl_1472 29 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 77461377 Common - Peptidase M16A, coenzyme PQQ biosynthesis protein PqqF Pfl_5156 175 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 77458883 Common - Hydrophobe/amphiphile efflux-1 HAE1 Pfl_2658 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77459257 Common - hypothetical protein Pfl_3035 5 None None None 77459357 Common - Putative Anti-Sigma-regulatory factor (Ser/Thr protein kinase) Pfl_3135 33 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 77456286 Common - homoserine kinase Pfl_0058 63 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 77459388 Common - Dyp-type peroxidase Pfl_3166 51 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 77461380 Common - pyrroloquinoline quinone biosynthesis protein PqqC Pfl_5159 39 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 77456440 Common - Transcriptional Regulator, LysR family Pfl_0212 188 COG0583 LysR, Transcriptional regulator Transcription 77460940 Common - Phospholipid/glycerol acyltransferase Pfl_4719 17 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 77457342 Common rnhB ribonuclease HII Pfl_1115 226 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 77460283 Common - DegT/DnrJ/EryC1/StrS aminotransferase Pfl_4062 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 77456265 Common - Protein of unknown function DUF140 Pfl_0037 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 77459204 Common - Aromatic-ring hydroxylase Pfl_2979 20 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 77458542 Common - FAD dependent oxidoreductase Pfl_2315 23 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77458019 Common - Benzoate membrane transport protein Pfl_1792 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 77460801 Common - hypothetical protein Pfl_4580 11 COG5513 COG5513, Predicted secreted protein Function unknown 77461778 Common - TonB-like Pfl_5557 34 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 77457920 Common minE cell division topological specificity factor MinE Pfl_1693 83 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 77459932 Common - hypothetical protein Pfl_3710 34 COG3812 COG3812, Uncharacterized protein conserved in bacteria Function unknown 77456314 Common - hypothetical protein Pfl_0086 18 None None None 77461171 Common - tRNA-i(6)A37 modification enzyme MiaB Pfl_4950 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 77460733 Nonpathogen - hypothetical protein Pfl_4512 1 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 77460398 Common - MotA/TolQ/ExbB proton channel Pfl_4177 154 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 77460522 Common - Transcriptional Regulator, AraC family Pfl_4301 66 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77460244 Common - hypothetical protein Pfl_4023 5 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 77457414 Common - Short-chain dehydrogenase/reductase SDR Pfl_1187 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77458861 Common - Mannitol dehydrogenase Pfl_2636 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 77460544 Common - Transcriptional Regulator, LysR family Pfl_4323 178 COG0583 LysR, Transcriptional regulator Transcription 77458183 Common - Transcriptional Regulator, AraC family Pfl_1956 158 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 77457173 Common - hypothetical protein Pfl_0946 1 None None None 77460430 Common - TonB-dependent receptor Pfl_4209 118 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 77460369 Common - Transcriptional Regulator, TetR family Pfl_4148 94 COG1309 AcrR, Transcriptional regulator Transcription 77459273 Common - hypothetical protein Pfl_3051 6 None None None 77457453 Common - hydrolase, putative Pfl_1226 11 None None None 77460628 Common ruvB Holliday junction DNA helicase B Pfl_4407 214 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 77459427 Common - hypothetical protein Pfl_3205 2 None None None 77457786 Nonpathogen - hypothetical protein Pfl_1559 1 None None None 77456373 Common - hypothetical protein Pfl_0145 106 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 77457089 Common - KpsF/GutQ Pfl_0862 189 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 77458827 Common uppP undecaprenyl pyrophosphate phosphatase Pfl_2602 199 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 77457083 Common - Sigma-54 modulation protein/ribosomal protein S30EA Pfl_0856 78 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 77457916 Common - hypothetical protein Pfl_1689 1 None None None 77460406 Common - hypothetical protein Pfl_4185 3 None None None 77461078 Common - gamma-glutamyl kinase Pfl_4857 192 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 77461126 Common - 4-hydroxyphenylpyruvate dioxygenase Pfl_4905 92 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 77461308 Common rplL 50S ribosomal protein L7/L12 Pfl_5087 213 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 77458376 Common - Transcriptional Regulator, LysR family Pfl_2149 172 COG0583 LysR, Transcriptional regulator Transcription 77460844 Nonpathogen - hypothetical protein Pfl_4623 1 None None None 77458992 Common - NADP oxidoreductase, coenzyme F420-dependent Pfl_2767 42 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 77459088 Common - Esterase/lipase/thioesterase Pfl_2863 117 COG0657 Aes, Esterase/lipase Lipid metabolism 77457104 Common - sulfate adenylyltransferase subunit 2 Pfl_0877 144 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 77461831 Common - Response regulator receiver domain protein (CheY) Pfl_5610 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 77458329 Common - malate:quinone oxidoreductase Pfl_2102 57 COG0579 COG0579, Predicted dehydrogenase General function prediction only 77458758 Nonpathogen - hypothetical protein Pfl_2533 1 None None None 77457617 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Pfl_1390 206 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 77459242 Common - hypothetical protein Pfl_3020 22 None None None 77460895 Common - Cell cycle protein Pfl_4674 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 77458310 Common - FAD dependent oxidoreductase Pfl_2083 50 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 77459214 Common - hypothetical protein Pfl_2992 14 None None None 77459359 Common - Histidine Kinase Pfl_3137 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77458794 Common - hypothetical protein Pfl_2569 1 None None None 77457894 Common - Bile acid:sodium symporter Pfl_1667 76 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 77461091 Common - hypothetical protein Pfl_4870 15 None None None 77461722 Common xerC site-specific tyrosine recombinase XerC Pfl_5501 228 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 77461506 Common - Cytochrome B561 Pfl_5285 82 COG3038 CybB, Cytochrome B561 Energy production and conversion 77457169 Common - hypothetical protein Pfl_0942 7 COG4460 COG4460, Uncharacterized protein conserved in bacteria Function unknown 77458485 Common - Major facilitator superfamily MFS_1 Pfl_2258 76 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 77460549 Common - hypothetical protein Pfl_4328 14 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 77456726 Common - hypothetical protein Pfl_0498 48 COG3150 COG3150, Predicted esterase General function prediction only 77460073 Common - hypothetical protein Pfl_3852 1 None None None 77457177 Common - alginate biosynthesis protein AlgF Pfl_0950 3 None None None 77458684 Common - Two Component Transcriptional Regulator, LuxR family Pfl_2459 183 COG4566 TtrR, Response regulator Signal transduction mechanisms 77459127 Common - PfkB Pfl_2902 181 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 77460578 Common - hypothetical protein Pfl_4357 21 None None None 77459717 Nonpathogen - hypothetical protein Pfl_3495 1 None None None 77458503 Common - Transcriptional regulatory protein-like Pfl_2276 142 COG5616 COG5616, Predicted integral membrane protein Function unknown 77461113 Common - Cytochrome bd ubiquinol oxidase, subunit II Pfl_4892 147 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 77457107 Common - phosphate acetyltransferase Pfl_0880 175 COG0280 Pta, Phosphotransacetylase Energy production and conversion 77461522 Common - triphosphoribosyl-dephospho-CoA synthase Pfl_5301 46 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 77461728 Common - Protein of unknown function DUF526 Pfl_5507 52 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 77460890 Common - Cell division protein FtsA Pfl_4669 192 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 77457014 Common - N-acetyl-anhydromuranmyl-L-alanine amidase Pfl_0787 109 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 77460594 Common - Two component Transcriptional regulator, Winged helix family Pfl_4373 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77460004 Common - Major facilitator superfamily MFS_1 Pfl_3782 46 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 77457952 Common - Acireductone dioxygenase, ARD Pfl_1725 37 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 77458855 Common - hypothetical protein Pfl_2630 2 None None None 77461768 Common rph ribonuclease PH Pfl_5547 201 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 77460043 Common - hypothetical protein Pfl_3821 3 None None None 77458443 Common - Transcriptional Regulator, LuxR family Pfl_2216 2 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 77460518 Common - HNH endonuclease Pfl_4297 26 COG3183 COG3183, Predicted restriction endonuclease Defense mechanisms 77456284 Common - DNA polymerase I Pfl_0056 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 77456322 Common - lipoprotein, putative Pfl_0094 1 None None None 77456622 Common - Poly(R)-hydroxyalkanoic acid synthase, class II Pfl_0394 72 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 77456959 Common - Glycosyl transferase, family 39 Pfl_0731 69 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 77456485 Common - glutamate--cysteine ligase Pfl_0257 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 77458339 Nonpathogen - hypothetical protein Pfl_2112 1 None None None 77459984 Common - hypothetical protein Pfl_3762 1 None None None 77457134 Common - ATP-dependent transcriptional regulator, MalT related, LuxR family Pfl_0907 101 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 77461144 Common - hypothetical protein Pfl_4923 17 COG4928 COG4928, Predicted P-loop ATPase General function prediction only 77460392 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase Pfl_4171 199 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 77456748 Common - N-acetylmuramoyl-L-alanine amidase Pfl_0520 172 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 77461691 Common - Cytochrome c, class I Pfl_5470 48 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 77461551 Common thiG thiazole synthase Pfl_5330 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 77461842 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit Pfl_5621 194 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 77457234 Common - Transcriptional Regulator, GntR family Pfl_1007 129 COG2188 PhnF, Transcriptional regulators Transcription 77456404 Common - Protein of unknown function DUF945 Pfl_0176 19 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 77459616 Common - Protein of unknown function DUF1289 Pfl_3394 16 COG3313 COG3313, Predicted Fe-S protein General function prediction only 77458006 Common - Molybdopterin oxidoreductase Pfl_1779 189 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 77458631 Common - Hemerythrin HHE cation binding region Pfl_2404 20 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 77456925 Common - Protein of unknown function DUF861 Pfl_0697 34 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 77456981 Common - regulatory protein GntR, HTH Pfl_0754 150 COG2186 FadR, Transcriptional regulators Transcription 77461545 Common - Methionine biosynthesis MetW Pfl_5324 65 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77461815 Common - Protein of unknown function DUF877 Pfl_5594 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 77459560 Common - Transcriptional Regulator, ArsR family Pfl_3338 68 COG0640 ArsR, Predicted transcriptional regulators Transcription 77459702 Common - Recombinase Pfl_3480 39 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 77460350 Nonpathogen - hypothetical protein Pfl_4129 1 None None None 77461924 Common - Two component Transcriptional regulator, Winged helix family Pfl_5704 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77461611 Common - Protein of unknown function DUF523 Pfl_5390 67 COG1683 COG1683, Uncharacterized conserved protein Function unknown 77458013 Common - dihydroorotate dehydrogenase 2 Pfl_1786 233 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 77456350 Common - Putative FecR Pfl_0122 41 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 77457113 Common - putative sulfate transport protein CysZ Pfl_0886 44 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 77456899 Common - adenosine deaminase Pfl_0671 101 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 77457554 Common - trans-aconitate methyltransferase, putative Pfl_1327 104 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 77459404 Nonpathogen - hypothetical protein Pfl_3182 1 None None None 77458233 Common - hypothetical protein Pfl_2006 43 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 77458588 Common - Transcriptional Regulator, LysR family Pfl_2361 148 COG0583 LysR, Transcriptional regulator Transcription 77456359 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Pfl_0131 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 77459445 Common - hypothetical protein Pfl_3223 1 None None None 77459690 Common - hypothetical protein Pfl_3468 39 None None None 77456595 Common - imidazolonepropionase Pfl_0367 109 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 77457224 Common - pyridoxal phosphate biosynthetic protein PdxJ Pfl_0997 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 77457880 Nonpathogen - hypothetical protein Pfl_1653 1 None None None 77458511 Common - hypothetical protein Pfl_2284 3 None None None 77461077 Common - CreA Pfl_4856 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 77458383 Common - DNA-3-methyladenine glycosylase II Pfl_2156 111 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 77458962 Common - Transcriptional Regulator, TetR family Pfl_2737 87 COG1309 AcrR, Transcriptional regulator Transcription 77458969 Common - Thiolase Pfl_2744 153 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 77460795 Common - hypothetical protein Pfl_4574 16 None None None 77458197 Common - Transcriptional Regulator, LysR family Pfl_1970 171 COG0583 LysR, Transcriptional regulator Transcription 77461256 Common - Protein of unknown function DUF72 Pfl_5035 107 COG1801 COG1801, Uncharacterized conserved protein Function unknown 77457561 Common - Alpha/beta hydrolase fold Pfl_1334 5 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77461729 Common - Mg chelatase-like protein Pfl_5508 190 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 77459059 Common - Phosphoglycerate/bisphosphoglycerate mutase Pfl_2834 4 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 77459156 Common - lipoprotein, putative Pfl_2931 2 None None None 77459662 Common - Permease for cytosine/purines, uracil, thiamine, allantoin Pfl_3440 83 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 77460626 Common - MotA/TolQ/ExbB proton channel Pfl_4405 146 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 77456982 Common smpB SsrA-binding protein Pfl_0755 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 77459569 Common - UspA Pfl_3347 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 77457775 Common - Flagellar biosynthesis protein, FliO Pfl_1548 10 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 77461009 Common - acetolactate synthase 3 catalytic subunit Pfl_4788 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 77459157 Common - hypothetical protein Pfl_2932 1 None None None 77461668 Common - HNH endonuclease Pfl_5447 9 None None None 77460297 Common - Chorismate mutase Pfl_4076 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 77458762 Common - Autotransporter beta-domain Pfl_2537 16 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 77461633 Common - Binding-protein-dependent transport systems inner membrane component Pfl_5412 204 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 77458718 Common - probable cytochrome c(mono-heme type) Pfl_2493 45 COG3245 CycB, Cytochrome c5 Energy production and conversion 77460399 Common - DNA internalization-like competence protein ComEC/Rec2 Pfl_4178 155 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 77459937 Nonpathogen - hypothetical protein Pfl_3715 1 None None None 77461419 Common - Phospholipid/glycerol acyltransferase Pfl_5198 30 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 77460419 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Pfl_4198 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77459996 Common - Propeptide, PepSY amd peptidase M4 Pfl_3774 5 COG3212 COG3212, Predicted membrane protein Function unknown 77461224 Common - hypothetical protein Pfl_5003 7 COG4676 COG4676, Uncharacterized protein conserved in bacteria Function unknown 77460812 Common - Transcriptional Regulator, LysR family Pfl_4591 190 COG0583 LysR, Transcriptional regulator Transcription 77460094 Common - cell division inhibitor, putative Pfl_3873 12 COG5404 SulA, SOS-response cell division inhibitor, blocks FtsZ ring formation Cell division and chromosome partitioning 77457162 Common - hypothetical protein Pfl_0935 19 COG5472 COG5472, Predicted small integral membrane protein Function unknown 77459220 Common - hypothetical protein Pfl_2998 22 None None None 77459697 Common - hypothetical protein Pfl_3475 23 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 77456911 Common - Transcriptional Regulator, TetR family Pfl_0683 92 COG1309 AcrR, Transcriptional regulator Transcription 77461335 Common trpD anthranilate phosphoribosyltransferase Pfl_5114 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 77457208 Common - hypothetical protein Pfl_0981 18 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77457094 Common - Anti-Sigma-factor antagonist (STAS) Pfl_0867 6 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 77458757 Common - MgtC/SapB transporter Pfl_2532 115 COG1285 SapB, Uncharacterized membrane protein Function unknown 77456475 Common - BCCT transporter Pfl_0247 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 77457544 Common - Protein of unknown function DUF606 Pfl_1317 40 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 77456976 Common - FAD linked oxidase-like Pfl_0749 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 77456512 Common nudE ADP-ribose diphosphatase NudE Pfl_0284 74 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 77458916 Common - PAS/PAC Sensor Hybrid Histidine Kinase Pfl_2691 197 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77460106 Common - hypothetical protein Pfl_3885 1 None None None 77461235 Common - thiamine monophosphate kinase Pfl_5014 202 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 77456893 Common - hypothetical protein Pfl_0665 1 None None None 77458209 Common - type II secretion system protein E Pfl_1982 215 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 77459695 Common - Cation efflux protein Pfl_3473 167 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 77458625 Common - Protein tyrosine phosphatase Pfl_2398 128 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 77457542 Common - Pyruvate carboxyltransferase Pfl_1315 185 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 77458896 Common - Pirin-like Pfl_2671 144 COG1741 COG1741, Pirin-related protein General function prediction only 77461133 Common - Aldo/keto reductase Pfl_4912 193 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 77456518 Common - hypothetical protein Pfl_0290 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 77456651 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Pfl_0423 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77456627 Common argS arginyl-tRNA synthetase Pfl_0399 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 77461917 Common - hypothetical protein Pfl_5697 28 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 77457125 Common - Transcriptional Regulator, LysR family Pfl_0898 173 COG0583 LysR, Transcriptional regulator Transcription 77457602 Common - hypothetical protein Pfl_1375 18 None None None 77457638 Common - hypothetical protein Pfl_1411 5 None None None 77459888 Common - Sigma-24 (FecI) Pfl_3666 112 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77461440 Common - Glucose-methanol-choline oxidoreductase Pfl_5219 45 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 77458280 Common - Arginine N-succinyltransferase beta subunit Pfl_2053 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 77461860 Common - acetyl-CoA carboxylase Pfl_5640 237 COG0439 AccC, Biotin carboxylase Lipid metabolism 77458104 Common - Secretion protein HlyD Pfl_1877 164 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 77458422 Common ppnK inorganic polyphosphate/ATP-NAD kinase Pfl_2195 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 77458960 Common - Phytanoyl-CoA dioxygenase Pfl_2735 16 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 77457731 Common flgI flagellar basal body P-ring protein Pfl_1504 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 77458330 Common - hypothetical protein Pfl_2103 22 None None None 77457618 Common - Nitroreductase Pfl_1391 59 COG0778 NfnB, Nitroreductase Energy production and conversion 77456880 Common - hypothetical protein Pfl_0652 48 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 77457189 Common - Polysaccharide deacetylase Pfl_0962 7 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 77457404 Common - hypothetical protein Pfl_1177 102 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 77457142 Common - Glu/Leu/Phe/Val dehydrogenase, dimerization region Pfl_0915 115 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 77459832 Common - NADH dehydrogenase subunit I Pfl_3610 191 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 77460132 Common - Peptidase M24 Pfl_3911 167 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 77456522 Common - hypothetical protein Pfl_0294 37 COG3531 COG3531, Predicted protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 77456397 Common - hypothetical protein Pfl_0169 23 None None None 77458703 Common - Short-chain dehydrogenase/reductase SDR Pfl_2478 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 77457073 Common - hypothetical protein Pfl_0846 59 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 77458617 Common - Protein of unknown function DUF633 Pfl_2390 30 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 77460142 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Pfl_3921 57 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 77458834 Common - ABC transporter-like Pfl_2609 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 77459284 Common - Plasmid stabilization system Pfl_3062 2 COG3668 ParE, Plasmid stabilization system protein General function prediction only 77461498 Common - Sodium/hydrogen exchanger Pfl_5277 167 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 77459143 Common - Protein of unknown function DUF6, transmembrane Pfl_2918 188 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 77460657 Common purU formyltetrahydrofolate deformylase Pfl_4436 219 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 77458644 Common - hypothetical protein Pfl_2419 1 None None None 77460260 Common - 3-oxoacyl-acyl carrier protein synthase II Pfl_4039 172 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 77456918 Common - Exodeoxyribonuclease V, alpha subunit Pfl_0690 123 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 77459501 Common - Transcriptional Regulator, LysR family Pfl_3279 183 COG0583 LysR, Transcriptional regulator Transcription 77461534 Common - pyrimidine regulatory protein PyrR Pfl_5313 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 77460302 Common - 3-demethylubiquinone-9 3-methyltransferase Pfl_4081 195 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 77456713 Common - hypothetical protein Pfl_0485 1 None None None 77460569 Common - GCN5-related N-acetyltransferase Pfl_4348 6 None None None 77461914 Nonpathogen - hypothetical protein Pfl_5694 1 None None None 77457641 Common - Aspartyl/Asparaginyl beta-hydroxylase Pfl_1414 36 COG3555 COG3555, Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases Posttranslational modification, protein turnover, chaperones 77458238 Nonpathogen - hypothetical protein Pfl_2011 11 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 77459879 Common - Propionyl-CoA carboxylase Pfl_3657 144 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 77459965 Common - Binding-protein-dependent transport systems inner membrane component Pfl_3743 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 77456957 Common - Phosphoglycerate/bisphosphoglycerate mutase Pfl_0729 4 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 77458287 Common - Phosphoglycerate/bisphosphoglycerate mutase Pfl_2060 52 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 77460223 Common - GreA/GreB family elongation factor Pfl_4002 14 COG0782 GreA, Transcription elongation factor Transcription 77458656 Common - Phosphonate uptake transporter Pfl_2431 91 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 77457245 Common - Signal recognition particle protein Pfl_1018 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 77457688 Common - ABC transporter, transmembrane region Pfl_1461 246 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 77458551 Common benD 1,6-dihydroxycyclohexa-2,4-diene-1-carboxylate dehydrogenase Pfl_2324 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77458054 Common - Cytochrome c oxidase cbb3-type, subunit I Pfl_1827 145 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 77457703 Common - hypothetical protein Pfl_1476 16 COG4341 COG4341, Predicted HD phosphohydrolase General function prediction only 77460571 Common - Ribonuclease BN Pfl_4350 141 COG1295 Rbn, Predicted membrane protein Function unknown 77457807 Common - Heme exporter protein D Pfl_1580 7 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 77461572 Common - formamidopyrimidine-DNA glycosylase Pfl_5351 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 77459019 Common - Transposase, IS4 Pfl_2794 49 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 77456451 Common - NLPA lipoprotein Pfl_0223 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 77458085 Common - RNA polymerase sigma factor Pfl_1858 106 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 77458548 Common - ring hydroxylating dioxygenase, alpha subunit Pfl_2321 81 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 77460160 Common - Alpha/beta hydrolase fold Pfl_3939 170 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 77459947 Common - ATPase Pfl_3725 42 COG3950 COG3950, Predicted ATP-binding protein involved in virulence General function prediction only 77460589 Common - Binding-protein-dependent transport systems inner membrane component Pfl_4368 149 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 77460776 Common - Response Regulator Receiver Signal Transduction Histidine Kinase Pfl_4555 222 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 77461312 Common nusG transcription antitermination protein NusG Pfl_5091 215 COG0250 NusG, Transcription antiterminator Transcription 77459534 Common - putative monovalent cation/H+ antiporter subunit D Pfl_3312 141 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 77461244 Common - Thioredoxin Pfl_5023 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 77459942 Common - Major facilitator superfamily MFS_1 Pfl_3720 91 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77460186 Common - hypothetical protein Pfl_3965 1 None None None 77461789 Nonpathogen - hypothetical protein Pfl_5568 1 None None None 77461481 Nonpathogen - hypothetical protein Pfl_5260 1 None None None 77458058 Nonpathogen - hypothetical protein Pfl_1831 1 None None None 77459044 Common - Glycosyl transferase, group 1 Pfl_2819 204 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 77456360 Common - hypothetical protein Pfl_0132 12 None None None 77456497 Common - Transcriptional Regulator, XRE family Pfl_0269 49 COG2944 COG2944, Predicted transcriptional regulator Transcription 77460252 Common - potassium-transporting ATPase subunit C Pfl_4031 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 77460729 Common - electron transport complex protein RnfA Pfl_4508 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 77458214 Common - type II and III secretion system protein Pfl_1987 137 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 77457254 Common - homoserine dehydrogenase Pfl_1027 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 77459575 Common - hypothetical protein Pfl_3353 15 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 77458294 Common - hypothetical protein Pfl_2067 1 None None None 77458525 Common - Isochorismatase hydrolase Pfl_2298 81 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 77459506 Common - Major facilitator superfamily MFS_1 Pfl_3284 106 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 77456876 Common - type II and III secretion system protein Pfl_0648 139 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 77460650 Common - hypothetical protein Pfl_4429 1 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 77460762 Common - GlpM Pfl_4541 14 COG3136 GlpM, Uncharacterized membrane protein required for alginate biosynthesis General function prediction only 77461731 Common - adenylylsulfate kinase Pfl_5510 143 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 77461796 Common - Serine/Threonine protein kinase Pfl_5575 146 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 77457252 Common xerD site-specific tyrosine recombinase XerD Pfl_1025 232 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 77459732 Common - Citrate-proton symport Pfl_3510 125 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 77456275 Common - Multi-sensor Signal Transduction Histidine Kinase Pfl_0047 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 77458672 Common - Ferredoxin Pfl_2447 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 77458808 Common - TonB-dependent siderophore receptor Pfl_2583 87 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 77457946 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase Pfl_1719 224 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 77459827 Common - bifunctional NADH:ubiquinone oxidoreductase subunit C/D Pfl_3605 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 77459177 Common - TonB-dependent receptor Pfl_2952 86 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 77459495 Common - Aldehyde dehydrogenase Pfl_3273 193 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 77460165 Common - Transcriptional Regulator, TetR family Pfl_3944 79 COG1309 AcrR, Transcriptional regulator Transcription 77461416 Common - sensory histidine kinase CreC Pfl_5195 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 77458926 Common - Formate dehydrogenase accessory protein Pfl_2701 37 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 77461560 Common - Peptidase M16-like Pfl_5339 171 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 77456410 Common - YbhB and YbcL Pfl_0182 118 COG1881 COG1881, Phospholipid-binding protein General function prediction only 77460378 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Pfl_4157 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 77460173 Common - Protein of unknown function DUF1255 Pfl_3952 52 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 77459781 Common - hypothetical protein Pfl_3559 1 None None None 77458651 Common - hypothetical protein Pfl_2426 1 None None None 77458411 Common - Beta-lactamase-like Pfl_2184 192 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 77458360 Common - Metal dependent phosphohydrolase, HD region Pfl_2133 88 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 77458790 Common - hypothetical protein Pfl_2565 2 COG3212 COG3212, Predicted membrane protein Function unknown 77459972 Common - Monooxygenase, FAD-binding Pfl_3750 133 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 77458558 Common - hypothetical protein Pfl_2331 2 None None None 77457008 Common - tRNA pseudouridine synthase B Pfl_0781 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 77459822 Common - GCN5-related N-acetyltransferase Pfl_3600 104 COG2153 ElaA, Predicted acyltransferase General function prediction only 77459232 Common - Lytic transglycosylase, catalytic Pfl_3010 44 None None None 77456792 Common - Possible Transcriptional Regulator, TetR family Pfl_0564 39 COG1309 AcrR, Transcriptional regulator Transcription 77456296 Common - Integrase, catalytic region Pfl_0068 136 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 77458774 Common glgA glycogen synthase Pfl_2549 154 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 77461434 Common - hypothetical protein Pfl_5213 9 None None None 77458454 Common - hypothetical protein Pfl_2227 24 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 77457370 Common - Phage Tail Collar Pfl_1143 32 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 77458272 Common - Protein of unknown function DUF796 Pfl_2045 34 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 77461879 Common - ABC transporter-like Pfl_5659 240 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 77457973 Nonpathogen - hypothetical protein Pfl_1746 1 None None None 77456885 Common - chemotaxis sensory transducer, Cache sensor Pfl_0657 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77457766 Common fliI flagellum-specific ATP synthase Pfl_1539 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 77458122 Common - Peptidoglycan-binding LysM Pfl_1895 39 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 77456544 Common - Alpha/beta hydrolase fold Pfl_0316 32 COG4757 COG4757, Predicted alpha/beta hydrolase General function prediction only 77457568 Common - ABC transporter-like Pfl_1341 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 77460536 Common - Propeptide, PepSY amd peptidase M4 Pfl_4315 4 COG3212 COG3212, Predicted membrane protein Function unknown 77459837 Common - NADH dehydrogenase subunit N Pfl_3615 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 77461586 Common - hypothetical protein Pfl_5365 16 COG4341 COG4341, Predicted HD phosphohydrolase General function prediction only 77458369 Common - FAD dependent oxidoreductase Pfl_2142 120 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 77456574 Common - thiamine biosynthesis protein ThiI Pfl_0346 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 77459467 Common - Peptidase M24A, methionine aminopeptidase, subfamily 1 Pfl_3245 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 77459112 Common - Nicotinamidase Pfl_2887 125 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 77460492 Common - Divalent cation transporter Pfl_4271 178 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 77461867 Common - hypothetical protein Pfl_5647 7 None None None 77461657 Common - hypothetical protein Pfl_5436 10 None None None 77461782 Common - hypothetical protein Pfl_5561 7 None None None 77456784 Common - ABC transporter-like Pfl_0556 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 77460138 Common - Acyl-CoA dehydrogenase-like Pfl_3917 86 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 77460644 Common - Multi-sensor Signal Transduction Histidine Kinase Pfl_4423 219 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 77457998 Common - lipase, putative Pfl_1771 14 COG2267 PldB, Lysophospholipase Lipid metabolism 77461856 Common - GCN5-related N-acetyltransferase Pfl_5636 81 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 77458337 Nonpathogen - hypothetical protein Pfl_2110 1 None None None 77458936 Common - Carbohydrate-selective porin OprB Pfl_2711 21 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 77461530 Common - glutathione synthetase Pfl_5309 124 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 77460982 Common - S-type Pyocin Pfl_4761 10 None None None 77457274 Common - Spermidine/putrescine ABC transporter ATP-binding subunit Pfl_1047 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 77460442 Common - Two component Transcriptional regulator, Winged helix family Pfl_4221 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 77460028 Common - PAAR Pfl_3806 13 COG4104 COG4104, Uncharacterized conserved protein Function unknown 77459478 Common - Transcriptional Regulator, AraC family Pfl_3256 88 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 77459471 Common - Cystathionine gamma-synthase Pfl_3249 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 77456998 Common - Ribosomal RNA methyltransferase RrmJ/FtsJ Pfl_0771 140 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 77457661 Common - Transcriptional Regulator, LysR family Pfl_1434 172 COG0583 LysR, Transcriptional regulator Transcription 77461449 Common - hypothetical protein Pfl_5228 7 None None None 77458905 Common - Type I secretion system ATPase, PrtD Pfl_2680 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 77458327 Common - chemotaxis sensory transducer Pfl_2100 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 77459895 Common - Spore coat U Pfl_3673 11 COG5430 COG5430, Uncharacterized secreted protein Function unknown 77460770 Common - NUDIX hydrolase Pfl_4549 15 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 77459271 Nonpathogen - hypothetical protein Pfl_3049 7 None None None 77458813 Common - Cof protein Pfl_2588 131 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 77460315 Common - Protein of unknown function DUF6, transmembrane Pfl_4094 53 COG2962 RarD, Predicted permeases General function prediction only 77460475 Common flgA flagellar basal body P-ring biosynthesis protein FlgA Pfl_4254 65 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 77461119 Common - tRNA (uracil-5-)-methyltransferase Pfl_4898 187 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 77457835 Common actP acetate permease Pfl_1608 178 COG4147 DhlC, Predicted symporter General function prediction only 77459456 Common - Flavin reductase-like, FMN-binding Pfl_3234 120 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 77460017 Common - Alkylhydroperoxidase AhpD core Pfl_3795 78 COG2128 COG2128, Uncharacterized conserved protein Function unknown 77459550 Nonpathogen - hypothetical protein Pfl_3328 1 None None None 77459580 Common - Glucose-methanol-choline oxidoreductase Pfl_3358 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 77461826 Common - hypothetical protein Pfl_5605 36 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 77460087 Common - Transcription-repair coupling factor Pfl_3866 235 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 77457313 Common - hypothetical protein Pfl_1086 5 None None None 77457506 Common - Hydrophobe/amphiphile efflux-1 HAE1 Pfl_1279 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 77459587 Common - GCN5-related N-acetyltransferase Pfl_3365 12 COG5628 COG5628, Predicted acetyltransferase General function prediction only 77460973 Common ipk 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase Pfl_4752 191 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 77461812 Nonpathogen - hypothetical protein Pfl_5591 1 None None None 77460446 Common - hypothetical protein Pfl_4225 1 None None None 77458408 Common - extracellular solute-binding protein, family 5 Pfl_2181 167 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 77459421 Common - Secretin/TonB, short-like Pfl_3199 19 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 77457885 Common - hypothetical protein Pfl_1658 1 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 77459849 Common - Protein of unknown function DUF181 Pfl_3627 16 COG1944 COG1944, Uncharacterized conserved protein Function unknown 77458667 Common - Glutathione S-transferase-like Pfl_2442 79 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 77460336 Common - extracellular solute-binding protein, family 3 Pfl_4115 10 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 77460970 Common hemA glutamyl-tRNA reductase Pfl_4749 181 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 77456630 Common - nuclease (SNase-like) Pfl_0402 51 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 77459150 Common - Alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Pfl_2925 218 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 77460824 Common - Type IV pilus biogenesis protein PilF Pfl_4603 106 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 77460021 Nonpathogen - hypothetical protein Pfl_3799 1 COG4907 COG4907, Predicted membrane protein Function unknown 77460346 Common - 2-keto-3-deoxy-galactonokinase Pfl_4125 41 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 77461593 Common - Transcriptional Regulator, MerR family Pfl_5372 130 COG0789 SoxR, Predicted transcriptional regulators Transcription 77461456 Common - hypothetical protein Pfl_5235 2 None None None 77456810 Common - GCN5-related N-acetyltransferase Pfl_0582 30 COG0456 RimI, Acetyltransferases General function prediction only 77457327 Common - methionine aminopeptidase Pfl_1100 245 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 77457681 Common - Na+/solute symporter Pfl_1454 146 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 77459679 Common - Protein of unknown function DUF81 Pfl_3457 65 COG0730 COG0730, Predicted permeases General function prediction only 77459543 Common - hypothetical protein Pfl_3321 1 None None None 77460977 Common - translation-associated GTPase Pfl_4756 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 77458307 Common - Acetamidase/Formamidase Pfl_2080 33 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion