Thiobacillus denitrificans ATCC 25259, complete genome NC_007404 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 74316655 Common - hypothetical protein Tbd_0637 12 None None None 74317402 Common - hydrogenase expression/formation protein HypD Tbd_1384 108 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 74317245 Common - 7-cyano-7-deazaguanine reductase Tbd_1227 112 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 74316827 Common - putative competence lipoprotein precursor Tbd_0809 119 COG4105 ComL, DNA uptake lipoprotein General function prediction only 74318267 Common - hypothetical protein Tbd_2249 6 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 74316878 Common metG methionyl-tRNA synthetase Tbd_0860 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74318205 Common - hypothetical protein Tbd_2187 84 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 74317408 Common - probable transmembrane regulatory nosR transcription regulator protein Tbd_1390 59 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 74316649 Nonpathogen - hypothetical protein Tbd_0631 1 None None None 74318790 Nonpathogen - hypothetical protein Tbd_2772 1 None None None 74316402 Common - hypothetical protein containing TPR repeat Tbd_0384 118 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 74317066 Nonpathogen - hypothetical protein Tbd_1048 1 None None None 74318360 Common - hypothetical protein Tbd_2342 13 None None None 74318433 Common - hypothetical protein Tbd_2415 38 COG1160 COG1160, Predicted GTPases General function prediction only 74317056 Common - hypothetical protein Tbd_1038 39 COG0730 COG0730, Predicted permeases General function prediction only 74317911 Common - ABC-2 type transport system permease protein Tbd_1893 125 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 74318244 Nonpathogen - hypothetical protein Tbd_2226 1 None None None 74316268 Nonpathogen - putative lipoprotein Tbd_0250 1 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 74318797 Common - uroporphyrinogen decarboxylase HemE Tbd_2779 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 74318339 Nonpathogen - putative secretion protein Tbd_2321 3 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74316645 Nonpathogen - hypothetical protein Tbd_0627 1 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 74316202 Common - thioredoxin family protein, putative Tbd_0184 146 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 74317810 Common - hypothetical protein Tbd_1792 30 None None None 74317865 Common - hypothetical protein Tbd_1847 5 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 74318212 Common - phosphatidylglycerophosphatase A Tbd_2194 77 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 74316895 Common - hypothetical protein Tbd_0877 37 COG3577 COG3577, Predicted aspartyl protease General function prediction only 74318670 Common - Nitrogen regulatory protein P-II (GlnB, GlnK) Tbd_2652 14 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 74318328 Common - assimilatory nitrate reductase Tbd_2310 187 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 74318762 Common - acyl carrier protein Tbd_2744 45 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 74317750 Common - hypothetical protein Tbd_1732 31 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 74316522 Common - acetyl-CoA synthetase Tbd_0504 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 74316779 Nonpathogen - hypothetical protein Tbd_0761 5 None None None 74316399 Common - probable ferredoxin protein Tbd_0381 123 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 74316864 Common - probable glutathione S-transferase Tbd_0846 102 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 74316353 Common - protoheme IX farnesyltransferase Tbd_0335 169 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 74318401 Nonpathogen - hypothetical protein Tbd_2383 1 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 74317691 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Tbd_1673 158 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 74316426 Common rplB 50S ribosomal protein L2 Tbd_0408 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 74316664 Common - Na+/H+ - glutamate/aspartate symport protein Tbd_0646 162 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 74317446 Common arsM arsenite S-adenosylmethyltransferase Tbd_1428 188 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 74316300 Common - polysaccharide chain length determinant protein Tbd_0282 75 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 74318599 Common - pyrimidine regulatory protein PyrR Tbd_2581 112 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 74317688 Common - oligopeptide ABC transporter permease protein Tbd_1670 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 74317307 Common - Multi-sensor Signal Transduction Histidine Kinase Tbd_1289 179 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 74316321 Nonpathogen - hypothetical protein Tbd_0303 5 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 74317085 Nonpathogen - hypothetical protein Tbd_1067 2 None None None 74316309 Common - glycosyl transferase, group 1 Tbd_0291 224 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74318739 Nonpathogen - hypothetical protein Tbd_2721 1 None None None 74318474 Common - dihydrouridine synthase Tbd_2456 211 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 74316685 Common - hypothetical protein Tbd_0667 11 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 74316982 Common cysM cysteine synthase B Tbd_0964 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 74318228 Common - 4-hydroxybenzoyl-CoA thioesterase Tbd_2210 135 COG0824 FcbC, Predicted thioesterase General function prediction only 74316639 Common eno phosphopyruvate hydratase Tbd_0621 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 74316957 Nonpathogen - hypothetical protein Tbd_0939 1 None None None 74316691 Common - plasmid maintenance system killer protein Tbd_0673 48 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 74318312 Common - phosphonate metabolism protein Tbd_2294 45 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 74318341 Common - oxidative stress transcriptional regulator Tbd_2323 182 COG0583 LysR, Transcriptional regulator Transcription 74318025 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Tbd_2007 139 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 74318833 Common - DEAD/DEAH box helicase Tbd_2815 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 74316698 Common - hypothetical protein Tbd_0680 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 74316949 Nonpathogen - hypothetical protein Tbd_0931 1 None None None 74316176 Common - myo-inositol-1(or 4)-monophosphatase Tbd_0158 198 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 74318445 Nonpathogen - SlyX protein Tbd_2427 1 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 74316342 Common - probable transmembrane protein Tbd_0324 5 COG5488 COG5488, Integral membrane protein Function unknown 74317208 Common - ATP-binding ABC transporter protein Tbd_1190 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 74318197 Common - hypothetical protein Tbd_2179 40 None None None 74316563 Nonpathogen - hypothetical protein Tbd_0545 5 None None None 74317436 Common - Secretion protein HlyD Tbd_1418 147 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 74318259 Nonpathogen - hypothetical protein Tbd_2241 1 None None None 74318743 Common - sodium:alanine symporter Tbd_2725 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 74317185 Common hscB co-chaperone HscB Tbd_1167 54 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 74317215 Common - hypothetical protein Tbd_1197 32 COG3809 COG3809, Uncharacterized protein conserved in bacteria Function unknown 74317181 Common - Iron-sulphur cluster assembly transcription factor IscR Tbd_1163 173 COG1959 COG1959, Predicted transcriptional regulator Transcription 74317136 Common - conserved hypothetical protein DUF209 Tbd_1118 147 COG1741 COG1741, Pirin-related protein General function prediction only 74318575 Common - glutamate-1-semialdehyde-2,1-aminomutase Tbd_2557 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 74317562 Common - aminodeoxychorismate lyase Tbd_1544 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 74317952 Common - integral membrane protein Tbd_1934 25 COG5528 COG5528, Predicted integral membrane protein Function unknown 74318728 Common - cobalamin-5-phosphate synthase CobS Tbd_2710 5 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 74316872 Common - isocitrate dehydrogenase (NADP) Tbd_0854 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 74318048 Common - DNA repair protein RecN Tbd_2030 199 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 74317736 Common - hypothetical protein Tbd_1718 81 None None None 74318705 Common - hypothetical protein Tbd_2687 84 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 74317104 Common - hypothetical protein Tbd_1086 60 COG3025 COG3025, Uncharacterized conserved protein Function unknown 74316603 Common - hypothetical protein Tbd_0585 58 COG2850 COG2850, Uncharacterized conserved protein Function unknown 74317054 Common - Camphor resistance CrcB protein Tbd_1036 49 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 74317401 Common - Hydrogenase accessory protein HypB Tbd_1383 104 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 74318584 Common - uroporphyrin-III C-methyltransferase Tbd_2566 50 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 74316034 Common - Fmu, rRNA SAM-dependent methyltransferase Tbd_0016 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 74316073 Common - cytochrome c family protein Tbd_0055 21 None None None 74316370 Nonpathogen - hypothetical protein Tbd_0352 4 None None None 74318331 Common - conserved hypothetical protein containing CBS domain Tbd_2313 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 74318723 Common - PhoH-like protein Tbd_2705 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 74317927 Common - colicin V production protein Tbd_1909 9 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 74317902 Common - putative nucleoside-diphosphate-sugar epimerase Tbd_1884 13 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74318076 Common - glycogen branching enzyme Tbd_2058 158 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 74318479 Common - coproporphyrinogen III oxidase Tbd_2461 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 74316677 Common - superoxide dismutase, Cu-Zn Tbd_0659 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 74317257 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Tbd_1239 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 74317095 Common - Predicted transcriptional regulator Tbd_1077 65 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 74318087 Common - hypothetical protein Tbd_2069 7 None None None 74318300 Common - adenylylsulfate reductase Tbd_2282 54 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 74318255 Common - Two Component Transcriptional Regulator, LuxR family Tbd_2237 220 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 74317754 Common - Putative Transcriptional Regulator, ArsR family Tbd_1736 44 COG0640 ArsR, Predicted transcriptional regulators Transcription 74316090 Common - Possible Transcriptional Regulator, AsnC family Tbd_0072 51 COG1522 Lrp, Transcriptional regulators Transcription 74318603 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_2585 175 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 74317533 Nonpathogen - hypothetical protein Tbd_1515 3 None None None 74317519 Nonpathogen - hypothetical protein Tbd_1501 1 None None None 74318422 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Tbd_2404 210 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 74317164 Common nuoE NADH dehydrogenase subunit E Tbd_1146 154 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 74318511 Common prfA peptide chain release factor 1 Tbd_2493 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 74317512 Common - hypothetical protein Tbd_1494 29 None None None 74317961 Common - putativel formate transporter Tbd_1943 95 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 74318093 Common - queuine tRNA-ribosyltransferase Tbd_2075 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 74317473 Common - N-formylglutamate amidohydrolase Tbd_1455 31 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 74318413 Common - Putative Transcriptional Regulator, ArsR family Tbd_2395 160 COG0640 ArsR, Predicted transcriptional regulators Transcription 74318001 Nonpathogen - hypothetical protein Tbd_1983 3 COG2210 COG2210, Uncharacterized conserved protein Function unknown 74316729 Common - putative biopolymer transport protein Tbd_0711 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 74316454 Common - Excinuclease ABC, A subunit Tbd_0436 233 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 74317625 Common fliM flagellar motor switch protein FliM Tbd_1607 115 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 74316812 Common - putative outer membrane protein Tbd_0794 60 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 74317039 Common - selenophosphate synthetase Tbd_1021 182 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 74318683 Common - hypothetical protein Tbd_2665 17 None None None 74316786 Common - probable aminotransferase Tbd_0768 233 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 74318313 Common phnH carbon-phosphorus lyase complex subunit Tbd_2295 26 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 74318164 Common - hypothetical protein Tbd_2146 44 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 74316415 Common rplL 50S ribosomal protein L7/L12 Tbd_0397 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 74316615 Common - pyrrolo-quinoline quinone Tbd_0597 103 COG1520 COG1520, FOG: WD40-like repeat Function unknown 74317265 Common flhF flagellar biosynthesis regulator FlhF Tbd_1247 111 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 74318041 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_2023 195 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 74317458 Common - type II secretion system transmembrane protein Tbd_1440 13 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74317037 Common - hypothetical protein Tbd_1019 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 74317920 Common - Cysteinyl-tRNA synthetase, class Ia Tbd_1902 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74317415 Common - hypothetical protein Tbd_1397 16 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 74317282 Nonpathogen - hypothetical protein Tbd_1264 1 None None None 74316377 Common - TonB-dependent receptor, putative Tbd_0359 8 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 74317496 Nonpathogen - hypothetical protein Tbd_1478 2 None None None 74316914 Common - ATP-dependent DNA helicase RecQ Tbd_0896 229 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 74317441 Common - putative phosphatase Tbd_1423 39 COG3211 PhoX, Predicted phosphatase General function prediction only 74318104 Common - ribonuclease III Tbd_2086 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 74316557 Common - monovalent cation:H+ antiporter-2, CPA2 family Tbd_0539 188 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 74318145 Common - thiamine-biosynthesis protein ThiS Tbd_2127 64 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 74316214 Common - conserve hypothetical protein containing TPR repeat Tbd_0196 120 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 74316582 Common - sulfur oxidation protein Tbd_0564 31 COG3258 COG3258, Cytochrome c Energy production and conversion 74318785 Common gltB glutamate synthase subunit alpha Tbd_2767 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 74316922 Common - Two Component Transcriptional Regulator, Fis family Tbd_0904 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 74317343 Common - probable copper resistance protein B Tbd_1325 43 COG3667 PcoB, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 74316960 Nonpathogen - hypothetical protein Tbd_0942 1 None None None 74316486 Common - TRAP dicarboxylate transporter, DctM subunit Tbd_0468 119 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 74316387 Nonpathogen - hypothetical protein Tbd_0369 2 None None None 74317999 Common - rhodanese-like protein Tbd_1981 152 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 74317792 Common - UDP-glucose 4-epimerase Tbd_1774 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 74318021 Common - hypothetical protein Tbd_2003 6 None None None 74317957 Common - hypothetical protein Tbd_1939 8 None None None 74316420 Common - translation elongation factor G Tbd_0402 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 74317718 Common - Serine/Threonine protein kinase Tbd_1700 157 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 74316166 Common - hypothetical protein Tbd_0148 69 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 74318635 Nonpathogen - hypothetical protein Tbd_2617 2 None None None 74317743 Common - glycoprotease, (M22) metallo-protease family Tbd_1725 174 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 74318521 Common - glutamine synthetase type I Tbd_2503 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 74317334 Common - hypothetical protein Tbd_1316 8 None None None 74316753 Nonpathogen - hypothetical protein Tbd_0735 4 None None None 74316886 Common - nitric oxide reductase activation protein Tbd_0868 45 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 74317176 Nonpathogen - hypothetical protein Tbd_1158 1 None None None 74316903 Common - probable putative transmembrane protein Tbd_0885 14 None None None 74316489 Common - Metal dependent phosphohydrolase, HD region Tbd_0471 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 74316117 Common - NAD-dependent epimerase/dehydratase Tbd_0099 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74316149 Common - SecA protein Tbd_0131 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 74318774 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Tbd_2756 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 74318437 Common - Pilus retraction protein PilT Tbd_2419 222 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 74318395 Common - methylated-DNA-(protein)-cysteine S-methyltransferase Tbd_2377 213 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 74318528 Nonpathogen - hypothetical protein Tbd_2510 1 None None None 74317351 Common - heavy metal efflux pump CzcA Tbd_1333 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 74318112 Common - hypothetical protein Tbd_2094 12 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 74317599 Common - Secretion protein HlyD Tbd_1581 84 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 74318677 Common - hypothetical protein Tbd_2659 6 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 74316456 Common - Single-strand binding protein Tbd_0438 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 74317356 Common - Transcriptional Regulator, MerR family Tbd_1338 107 COG0789 SoxR, Predicted transcriptional regulators Transcription 74316748 Common - Transcriptional Regulator, Fis family Tbd_0730 171 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 74317893 Common - glycosyl transferase, group 2 family protein Tbd_1875 160 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 74317429 Common - Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain Tbd_1411 183 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 74318371 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Tbd_2353 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74318806 Common - putative thiol:disulfide interchange protein Tbd_2788 104 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 74317374 Common - RND efflux system outer membrane lipoprotein NodT Tbd_1356 106 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74318169 Common - TRAP dicarboxylate transporter, DctM subunit Tbd_2151 121 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 74317782 Common - hypothetical protein Tbd_1764 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 74317653 Common flgD flagellar basal body rod modification protein Tbd_1635 109 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 74316432 Common - ribosomal protein S17 Tbd_0414 217 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 74317078 Nonpathogen - hypothetical protein Tbd_1060 1 None None None 74317502 Nonpathogen - hypothetical protein Tbd_1484 1 COG2863 COG2863, Cytochrome c553 Energy production and conversion 74317778 Common - lipoprotein releasing system, ATP-binding protein Tbd_1760 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 74316874 Common - hypothetical protein Tbd_0856 23 COG4394 COG4394, Uncharacterized protein conserved in bacteria Function unknown 74316086 Common - metallo-beta-lactamase superfamily protein Tbd_0068 218 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 74317453 Nonpathogen - hypothetical protein Tbd_1435 5 None None None 74317040 Common - hypothetical protein Tbd_1022 79 COG1262 COG1262, Uncharacterized conserved protein Function unknown 74317231 Nonpathogen - hypothetical protein Tbd_1213 1 None None None 74317464 Common - DNA polymerase X Tbd_1446 76 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 74317820 Nonpathogen - hypothetical protein Tbd_1802 1 None None None 74317030 Common - phenylalanyl-tRNA synthetase, beta subunit Tbd_1012 242 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 74317378 Common - ABC transporter permease protein Tbd_1360 42 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 74318664 Common - carboxysome shell protein, CsoS1C Tbd_2646 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 74317632 Common - Response regulator receiver domain protein (CheY) Tbd_1614 210 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 74316198 Common prmA ribosomal protein L11 methyltransferase Tbd_0180 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 74317507 Common - Appr-1-p processing protein Tbd_1489 31 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 74316119 Common - peptidase S13, D-Ala-D-Ala carboxypeptidase C Tbd_0101 108 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 74318563 Common - putative cytochrome c Tbd_2545 79 COG3258 COG3258, Cytochrome c Energy production and conversion 74316792 Common - putative oxygen-binding protein (globin) Tbd_0774 70 COG2346 COG2346, Truncated hemoglobins General function prediction only 74317297 Common - hypothetical protein Tbd_1279 37 COG3528 COG3528, Uncharacterized protein conserved in bacteria Function unknown 74317420 Common - nitrate/nitrite antiporter Tbd_1402 82 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 74316101 Common - D-alanyl-D-alanine carboxypeptidase-like protein Tbd_0083 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 74316157 Common - cytochrome b, putative Tbd_0139 7 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 74318096 Common - preprotein translocase protein YajC Tbd_2078 130 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 74316716 Common - NusA antitermination factor Tbd_0698 221 COG0195 NusA, Transcription elongation factor Transcription 74317729 Common hisB imidazoleglycerol-phosphate dehydratase Tbd_1711 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 74316706 Common - hypothetical protein Tbd_0688 26 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 74317973 Common - phosphoribulokinase-like protein Tbd_1955 51 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 74318536 Nonpathogen - hypothetical protein Tbd_2518 1 COG1950 COG1950, Predicted membrane protein Function unknown 74316109 Common - chaperonin GroEL (Hsp60, Cpn10) Tbd_0091 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 74318545 Common - hypothetical protein Tbd_2527 45 COG3159 COG3159, Uncharacterized protein conserved in bacteria Function unknown 74316979 Common - UDP-glucose dehydrogenase Tbd_0961 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 74318735 Common - nitroreductase-like protein Tbd_2717 105 COG0778 NfnB, Nitroreductase Energy production and conversion 74317640 Common - chemotaxis sensory transducer Tbd_1622 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 74318054 Common - universal stress protein (Usp) Tbd_2036 37 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 74316774 Common - hypothetical protein Tbd_0756 12 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 74317159 Common secG preprotein translocase subunit SecG Tbd_1141 9 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 74316526 Common - hypothetical protein Tbd_0508 126 COG0431 COG0431, Predicted flavoprotein General function prediction only 74318292 Common - nitrate transport ATP-binding subunits C and D Tbd_2274 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 74316328 Common - putative polysaccharide deacetylase Tbd_0310 98 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 74317567 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Tbd_1549 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 74317348 Nonpathogen - hypothetical protein Tbd_1330 1 None None None 74316129 Common - methyltransferase Tbd_0111 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 74318499 Common - DsrH protein Tbd_2481 27 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 74316780 Common - hypothetical protein Tbd_0762 9 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 74318074 Common - phosphorylase Tbd_2056 121 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 74316856 Common - RNA polymerase sigma factor RpoS Tbd_0838 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 74317731 Common - histidinol dehydrogenase Tbd_1713 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 74318095 Common - putative Zn-dependent protease Tbd_2077 117 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 74316278 Common - Cell shape determining protein MreB/Mrl Tbd_0260 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 74316164 Common - probable cytochrome c5 Tbd_0146 46 COG3245 CycB, Cytochrome c5 Energy production and conversion 74318455 Common - ribonuclease E and G Tbd_2437 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 74318841 Common - putative phage integrase Tbd_2823 111 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 74317649 Common - flagellar L-ring protein precursor FlgH Tbd_1631 91 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 74318156 Common - phosphomannomutase Tbd_2138 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 74316490 Common - RNA polymerase, omega subunit Tbd_0472 113 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 74318817 Common - F0F1 ATP synthase subunit alpha Tbd_2799 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 74318461 Common - DNA polymerase III, delta subunit Tbd_2443 80 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 74316314 Nonpathogen - hypothetical protein Tbd_0296 2 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 74316510 Common - putative monovalent cation/H+ antiporter subunit G Tbd_0492 76 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 74318119 Common - DnaB helicase Tbd_2101 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 74316337 Common - biotin synthase Tbd_0319 171 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 74318043 Common - histone deacetylase family protein Tbd_2025 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 74316112 Nonpathogen - hypothetical protein Tbd_0094 7 None None None 74318220 Common - ExsB ATPase Tbd_2202 178 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 74317364 Nonpathogen - hypothetical protein Tbd_1346 1 None None None 74318183 Common - glycine/serine hydroxymethyltransferase 1 Tbd_2165 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 74318810 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Tbd_2792 178 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74317554 Common - glycosyltransferase, group 2 family protein Tbd_1536 192 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 74317272 Common - hypothetical protein Tbd_1254 129 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 74318173 Nonpathogen - hypothetical protein Tbd_2155 8 None None None 74316988 Common rumA 23S rRNA (uracil-5-)-methyltransferase Tbd_0970 198 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 74316184 Common - ATP-dependent DNA helicase Tbd_0166 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 74316597 Common - putative DNA polymerase III chi subunit Tbd_0579 67 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 74318382 Common cbbI ribose-5-phosphate isomerase A Tbd_2364 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 74317369 Common - transcriptional regulator Tbd_1351 3 COG2944 COG2944, Predicted transcriptional regulator Transcription 74318655 Common cbbQ2 rubisco activation protein CbbQ Tbd_2637 84 COG0714 COG0714, MoxR-like ATPases General function prediction only 74318378 Common - putative tRNA nucleotidyltransferase/poly(A) polymerase Tbd_2360 230 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 74318354 Common - domain of unknown function DUF227 Tbd_2336 91 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 74317738 Common - hypothetical protein Tbd_1720 86 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 74318367 Common - hypothetical protein Tbd_2349 129 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 74316962 Common - hypothetical protein Tbd_0944 34 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 74318641 Common cbbS ribulose-bisphosphate carboxylase form I small chain Tbd_2623 29 COG4451 RbcS, Ribulose bisphosphate carboxylase small subunit Energy production and conversion 74316122 Common - Carboxylyase-related protein Tbd_0104 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 74316750 Common - RNA polymease sigma-54 factor protein Tbd_0732 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 161899032 Common - argininosuccinate synthase Tbd_1849 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 74318263 Nonpathogen - hypothetical protein Tbd_2245 1 None None None 74318691 Common - hypothetical protein Tbd_2673 70 COG0730 COG0730, Predicted permeases General function prediction only 74316842 Common - nitric oxide reductase activation protein NorQ Tbd_0824 90 COG0714 COG0714, MoxR-like ATPases General function prediction only 74318284 Common - heavy metal translocating P-type ATPase Tbd_2266 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 74316248 Common - two-component system sensor ATPase Tbd_0230 102 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 74316932 Nonpathogen - hypothetical protein containing twin-arginine translocation pathway signal Tbd_0914 1 None None None 74318301 Common - adenylylsulfate reductase, beta subunit Tbd_2283 35 COG1146 COG1146, Ferredoxin Energy production and conversion 74317147 Common - GreA/GreB family elongation factor Tbd_1129 204 COG0782 GreA, Transcription elongation factor Transcription 74317875 Common - isoleucyl-tRNA synthetase, class Ia Tbd_1857 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74318766 Common - putative lauroyl/myristoyl acyltransferase involved in LPS biosynthesis Tbd_2748 52 COG4261 COG4261, Predicted acyltransferase General function prediction only 74318698 Common - type I restriction-modification system methyltransferase subunit Tbd_2680 158 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 74317612 Common - flagellar protein FliT Tbd_1594 13 None None None 74318125 Common dcd deoxycytidine triphosphate deaminase Tbd_2107 149 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 74317195 Common - flagellar biosynthesis protein FlhA Tbd_1177 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 74317242 Common - hypothetical protein Tbd_1224 3 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 74318513 Nonpathogen - hypothetical protein Tbd_2495 2 None None None 74316204 Common - probable cytochrome c-type biogenesis protein Tbd_0186 63 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 74318030 Common - putative esterase Tbd_2012 91 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 74316539 Nonpathogen - hypothetical protein Tbd_0521 1 None None None 74318714 Common - rhodanese-like protein Tbd_2696 142 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 74318427 Common - glutathione synthetase Tbd_2409 130 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 74316999 Nonpathogen - hypothetical protein Tbd_0981 1 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 74318130 Common - prolyl-tRNA synthetase Tbd_2112 239 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74318138 Common - GTPase Tbd_2120 111 COG1161 COG1161, Predicted GTPases General function prediction only 74317203 Common - succinate dehydrogenase Tbd_1185 199 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 74318117 Nonpathogen - hypothetical protein Tbd_2099 1 None None None 74318779 Nonpathogen - putative outer membrane protein Tbd_2761 7 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 74317264 Common - Flagellar biosynthesis protein FlhA Tbd_1246 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 74317087 Nonpathogen - hypothetical protein Tbd_1069 1 None None None 74316689 Common - Putative Adenylate/Guanylate Cyclase Tbd_0671 101 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 74316076 Common - ribonucleoside-diphosphate reductase alpha chain Tbd_0058 221 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 74317183 Common - scaffold protein Tbd_1165 151 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 74317271 Common - hypothetical protein Tbd_1253 43 COG2210 COG2210, Uncharacterized conserved protein Function unknown 74317808 Nonpathogen - hypothetical protein Tbd_1790 1 None None None 74317521 Nonpathogen - hypothetical protein Tbd_1503 2 None None None 74318440 Common - hypothetical protein Tbd_2422 38 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 74317431 Common - ABC transporter ATPase Tbd_1413 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 74316228 Common - bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein Tbd_0210 152 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 74317840 Nonpathogen - hypothetical protein Tbd_1822 1 None None None 74317619 Common - flagellar motor switch protein FliG Tbd_1601 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 74317805 Nonpathogen - hypothetical protein Tbd_1787 1 None None None 74316242 Nonpathogen - hypothetical protein Tbd_0224 1 None None None 74317222 Common - PhnB protein Tbd_1204 65 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 74317932 Common - tryptophan synthase subunit beta Tbd_1914 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 74317486 Common - hypothetical protein Tbd_1468 38 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 74317676 Common - Putative Anti-Sigma-28 factor, FlgM Tbd_1658 19 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 74317386 Nonpathogen - hypothetical protein Tbd_1368 1 None None None 74316330 Common - hypothetical protein Tbd_0312 30 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 74317993 Common - ribonucleotide-diphosphate reductase subunit beta Tbd_1975 160 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 74318408 Common - adenylyltransferase Tbd_2390 206 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 74316029 Common - Smg protein Tbd_0011 37 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 74318062 Common - heavy metal translocating P-type ATPase Tbd_2044 228 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 74316156 Common - cytochrome c'' Tbd_0138 13 None None None 74317917 Common - Protein of unknown function DUF140 Tbd_1899 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 74316838 Common - cytochrome c peroxidase Tbd_0820 37 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 74316045 Common - hypothetical protein Tbd_0027 182 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 74316844 Nonpathogen - hypothetical protein Tbd_0826 1 None None None 74316755 Common - glycosyl transferase probable ADP-heptose:LPS heptosyltransferase Tbd_0737 54 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 74316394 Common - Cell division transporter substrate-binding protein FtsY Tbd_0376 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 74316623 Nonpathogen - hypothetical protein Tbd_0605 1 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 74318754 Common - rhodanese-like protein Tbd_2736 164 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 74316579 Common - nitric-oxide reductase subunit B Tbd_0561 123 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 74318630 Nonpathogen - hypothetical protein Tbd_2612 1 None None None 74316446 Common - 30S ribosomal protein S11 Tbd_0428 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 74316935 Common - sulfur oxidation protein SoxX Tbd_0917 10 None None None 74318232 Common - Crossover junction endodeoxyribonuclease RuvC Tbd_2214 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 74316407 Common - peptidyl-tRNA hydrolase Tbd_0389 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 74317663 Common - heterodisulfide reductase, B subunit Tbd_1645 49 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 74317942 Common - hypothetical protein Tbd_1924 56 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 74316807 Common - di-trans-poly-cis-decaprenylcistransferase Tbd_0789 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 74317173 Common nuoN NADH dehydrogenase subunit N Tbd_1155 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 74317939 Common leuD isopropylmalate isomerase small subunit Tbd_1921 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 74318506 Common - putative sulfite reductase gamma chain Tbd_2488 58 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 74316866 Nonpathogen - hypothetical protein Tbd_0848 1 COG5373 COG5373, Predicted membrane protein Function unknown 74316471 Common rplM 50S ribosomal protein L13 Tbd_0453 234 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 74317789 Common - RecJ exonuclease Tbd_1771 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 74316236 Common - hypothetical protein Tbd_0218 78 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 74316464 Common - phospholipase D/Transphosphatidylase Tbd_0446 148 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 74316362 Nonpathogen - Cytochrome oxidase maturation protein cbb3-type Tbd_0344 1 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 74317588 Common - Cyclic nucleotide-binding domain (cNMP-BD) protein Tbd_1570 4 COG1295 Rbn, Predicted membrane protein Function unknown 74316559 Nonpathogen - hypothetical protein Tbd_0541 3 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74317740 Common - hypothetical protein Tbd_1722 38 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 74318023 Common - probable cp4-like integrase protein Tbd_2005 104 COG0582 XerC, Integrase DNA replication, recombination, and repair 74317870 Common - hypothetical protein Tbd_1852 19 COG3748 COG3748, Predicted membrane protein Function unknown 74318011 Nonpathogen - hypothetical protein Tbd_1993 2 COG4831 COG4831, Uncharacterized conserved protein Function unknown 74316030 Common - SMF protein Tbd_0012 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 74316422 Common rpsJ 30S ribosomal protein S10 Tbd_0404 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 74317475 Nonpathogen - hypothetical protein Tbd_1457 6 None None None 74318310 Common - ABC phosphonate transport system ATPase Tbd_2292 249 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 74318741 Common - hypothetical protein Tbd_2723 51 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 74317698 Nonpathogen - hypothetical protein Tbd_1680 1 None None None 74316637 Common - CTP synthetase Tbd_0619 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 74318780 Common - hypothetical protein Tbd_2762 14 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 74318493 Common - iron-sulfur cluster protein Tbd_2475 162 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 74318787 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Tbd_2769 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74318447 Common - Conserved hypothetical protein 22 Tbd_2429 27 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 74316984 Nonpathogen - hypothetical protein Tbd_0966 3 None None None 74317544 Common - putative integral membrane transmembrane protein Tbd_1526 81 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 74317734 Nonpathogen - hypothetical protein Tbd_1716 2 None None None 74317217 Common - hypothetical protein Tbd_1199 10 None None None 74316177 Common cbbT transketolase Tbd_0159 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 74316605 Common - fkbp-type peptidyl-prolyl cis-trans isomerase Tbd_0587 116 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 74316947 Nonpathogen - hypothetical protein Tbd_0929 1 None None None 74316805 Common - uridylate kinase Tbd_0787 215 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 74318352 Common - putative XAA-PRO aminopeptidase Tbd_2334 232 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 74318472 Common - outer membrane protein Tbd_2454 172 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 74317002 Common - cAMP phosphodiesterase class-II Tbd_0984 21 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 74316325 Nonpathogen - hypothetical protein Tbd_0307 1 None None None 74316340 Common - Biotin biosynthesis protein BioC Tbd_0322 133 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 74317133 Common - membrane protein Tbd_1115 127 COG2860 COG2860, Predicted membrane protein Function unknown 74318586 Common - porphobilinogen deaminase Tbd_2568 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 74318279 Nonpathogen - hypothetical protein Tbd_2261 1 None None None 74316647 Common - phosphoribosylformylglycinamidine synthase Tbd_0629 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 74317259 Common - transcriptional activator FlhC Tbd_1241 27 None None None 74318702 Common - HNH nuclease Tbd_2684 5 None None None 74317451 Common - type II secretion system protein F Tbd_1433 140 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 74316919 Common - Secretion protein HlyD Tbd_0901 79 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 74318463 Common - leucyl-tRNA synthetase, class Ia Tbd_2445 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74316732 Common - hypothetical protein Tbd_0714 23 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 74318195 Common - hypothetical protein Tbd_2177 16 None None None 74316546 Common - hypothetical protein Tbd_0528 12 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 74317910 Common - hypothetical protein Tbd_1892 118 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 74317550 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Tbd_1532 154 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 74316025 Common - Histone-like DNA-binding protein Tbd_0007 178 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 74318439 Nonpathogen - hypothetical protein Tbd_2421 2 None None None 74317877 Common - putative FKBP-type peptidyl-prolyl cis-trans isomerase 2 Tbd_1859 108 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 74316272 Common - DNA-(apurinic or apyrimidinic site) lyase Tbd_0254 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 74317959 Common - cyanate hydratase Tbd_1941 41 COG1513 CynS, Cyanate lyase Inorganic ion transport and metabolism 74316653 Common - coproporphyrinogen III oxidase Tbd_0635 201 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 74316349 Common - hypothetical protein Tbd_0331 5 None None None 74318628 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Tbd_2610 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74318435 Common - delta 1-pyrroline-5-carboxylate reductase Tbd_2417 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 74316053 Common - 7Fe ferredoxin:4Fe-4S ferredoxin, iron-sulfur binding domain Tbd_0035 152 COG1146 COG1146, Ferredoxin Energy production and conversion 74318399 Common - dihydroneopterin aldolase Tbd_2381 65 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 74316737 Common - transport protein Tbd_0719 10 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 74318246 Common - anthranilate synthase component I Tbd_2228 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 74317058 Nonpathogen - hypothetical protein Tbd_1040 2 None None None 74316138 Common murC UDP-N-acetylmuramate--L-alanine ligase Tbd_0120 210 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 74318795 Nonpathogen - hypothetical protein Tbd_2777 2 None None None 74317068 Common - glutathione S-transferase family protein Tbd_1050 20 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 74317093 Nonpathogen - hypothetical protein Tbd_1075 1 None None None 74318057 Common - dihydrofolate reductase Tbd_2039 149 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 74316519 Common - Ca2+:cation antiporter, CaCA family Tbd_0501 99 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 74318207 Common - riboflavin synthase subunit alpha Tbd_2189 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 74316650 Common - exporter of the RND superfamily Tbd_0632 81 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 74317406 Common - conserved hypothetical protein containing CBS domain Tbd_1388 146 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 74316288 Common - anthranilate phosphoribosyltransferase-like protein Tbd_0270 35 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 74316434 Common - ribosomal protein L24 Tbd_0416 211 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 74318359 Common - hypothetical protein Tbd_2341 168 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 74318235 Common - hypothetical protein Tbd_2217 18 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 74317672 Common - Sigma-24 (FecI) Tbd_1654 122 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 74317237 Common - hypothetical protein Tbd_1219 129 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 74318326 Common - nitrite reductase (NAD(P)H) small subunit Tbd_2308 85 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 74316897 Common - 1-deoxy-D-xylulose-5-phosphate synthase Tbd_0879 228 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 74317061 Common - hypothetical protein Tbd_1043 3 None None None 74318214 Common - hypothetical protein Tbd_2196 37 COG2378 COG2378, Predicted transcriptional regulator Transcription 74317757 Common - putative tetrathionate reductase subunit B Tbd_1739 145 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 74317604 Common - hypothetical protein Tbd_1586 80 COG1355 COG1355, Predicted dioxygenase General function prediction only 74318548 Nonpathogen - hypothetical protein Tbd_2530 1 None None None 74317772 Common - hypothetical protein Tbd_1754 70 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 74318793 Nonpathogen - hypothetical protein Tbd_2775 1 None None None 74317631 Common - chemotaxis regulator CheZ Tbd_1613 42 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 74317819 Common - undecaprenyl-phosphate galactosephosphotransferase Tbd_1801 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 74317102 Common - HlyD family secretion protein Tbd_1084 88 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 74317686 Common - oligopeptidee ABC transporter, ATP-binding protein Tbd_1668 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 74316916 Common - hypothetical protein Tbd_0898 14 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 74318772 Common - hypothetical protein Tbd_2754 23 None None None 74318144 Common thiG thiazole synthase Tbd_2126 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 74318541 Common - lipid A biosynthesis lauroyl acyltransferase Tbd_2523 97 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 74317969 Common - Fe-S-cluster redox enzyme, radical SAM family Tbd_1951 193 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 74316555 Common - Phosphatase kdsC Tbd_0537 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 74316379 Common - ankyrin Tbd_0361 81 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 74318789 Common - Two Component Transcriptional Regulator, Fis family Tbd_2771 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 74316417 Common - DNA-directed RNA polymerase subunit beta' Tbd_0399 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 74316696 Common - putative aspartyl protease Tbd_0678 41 COG3577 COG3577, Predicted aspartyl protease General function prediction only 74316191 Common - glycine dehydrogenase subunit 2 Tbd_0173 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 74316270 Common - hypothetical protein Tbd_0252 51 COG2836 COG2836, Uncharacterized conserved protein Function unknown 74318307 Common - guanylate kinase/L-type calcium channel region Tbd_2289 140 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 74317152 Common - dihydropteroate synthase Tbd_1134 217 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 74318046 Common - probable high affinity sulfate transporter (SulP) Tbd_2028 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 74316870 Common - putative hydrolase Tbd_0852 53 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 74318764 Common - conserved hypothetical protein, potential CoA ligase (AMP forming) Tbd_2746 114 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 74316240 Common - hypothetical protein Tbd_0222 79 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 74316409 Common - elongation factor Tu Tbd_0391 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 74317795 Common - dTDP-4-dehydrorhamnose reductase Tbd_1777 170 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 74317528 Common - probable exbB-like biopolymer transport Tbd_1510 153 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 74316924 Common - superoxide dismutase, Cu/Zn Tbd_0906 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 74318106 Common - peptidase S26A, signal peptidase I Tbd_2088 212 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 74318397 Common - putative succinylglutamate desuccinylase Tbd_2379 20 COG3608 COG3608, Predicted deacylase General function prediction only 74317724 Common - phosphoribosyl-ATP pyrophosphohydrolase Tbd_1706 181 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 74316905 Common - peptidase S33, proline iminopeptidase 1 Tbd_0887 118 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 74318489 Common - uroporphyrin-III C-methyltransferase Tbd_2471 204 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 74317741 Common - putative phage DNA polymerase Tbd_1723 158 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 74317124 Common - putative oxidative stress related rubrerythrin protein Tbd_1106 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 74316998 Common - ABC-type transport system ipermease component Tbd_0980 55 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 74316350 Common - SURF1 family protein Tbd_0332 66 COG3346 COG3346, Uncharacterized conserved protein Function unknown 74317419 Common - nitrate/proton symporter Tbd_1401 128 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 74318718 Common - hypothetical protein Tbd_2700 27 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 74317794 Common - GDP-mannose 4,6-dehydratase Tbd_1776 227 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 74316391 Nonpathogen - hypothetical protein Tbd_0373 1 None None None 74317413 Common - hypothetical protein Tbd_1395 4 None None None 74316462 Common ntpA dATP pyrophosphohydrolase Tbd_0444 48 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 74318650 Common - methionine sulfoxide reductase A Tbd_2632 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 74318573 Common - phosphomethylpyrimidine kinase Tbd_2555 221 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 74316302 Nonpathogen - hypothetical protein Tbd_0284 14 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 74316719 Common - Excinuclease ABC, C subunit Tbd_0701 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 74318637 Common - CopG family protein Tbd_2619 9 None None None 74316385 Common - hypothetical protein Tbd_0367 5 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 74317178 Common - inositol monophosphatase Tbd_1160 215 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 74318085 Nonpathogen - hypothetical protein Tbd_2067 1 None None None 74317358 Common - Mercuric transport protein periplasmic component Tbd_1340 73 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 74316334 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein Tbd_0316 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 74317986 Common - Anti-Sigm factor, ChrR Tbd_1968 27 COG3806 ChrR, Transcriptional activator Transcription 74318696 Common - hypothetical protein Tbd_2678 7 None None None 74318333 Common - putative rubredoxin reductase Tbd_2315 212 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 74318257 Common - hypothetical protein Tbd_2239 38 None None None 74318608 Common - ribosomal protein L33 Tbd_2590 139 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 74317014 Common - hypothetical protein Tbd_0996 5 COG2267 PldB, Lysophospholipase Lipid metabolism 74316099 Common - 2-hydroxy-3-oxopropionate reductase Tbd_0081 173 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 74317252 Common - hypothetical protein Tbd_1234 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 74318601 Common - dihydroorotase Tbd_2583 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 74318269 Common - transport-associated Tbd_2251 27 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 74317494 Common - hypothetical protein Tbd_1476 22 COG2327 WcaK, Uncharacterized conserved protein Function unknown 74316720 Common - putative isomerase Tbd_0702 13 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 74318758 Common - heavy metal translocating P-type ATPase Tbd_2740 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 74318225 Common - putative TonB protein Tbd_2207 23 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 74316216 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Tbd_0198 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74316410 Common secE preprotein translocase subunit SecE Tbd_0392 31 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 74317925 Common - O-succinylhomoserine sulfhydrylase Tbd_1907 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 74318415 Common - acriflavin resistance protein Tbd_2397 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 74316071 Nonpathogen - hypothetical protein Tbd_0053 2 None None None 74316424 Common rplD 50S ribosomal protein L4 Tbd_0406 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 74318162 Common - possible transmembrane protein Tbd_2144 30 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 74318681 Common - exported protein Tbd_2663 87 COG1430 COG1430, Uncharacterized conserved protein Function unknown 74316196 Common gcvT glycine cleavage system aminomethyltransferase T Tbd_0178 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 74317627 Nonpathogen - flagellar biogenesis protein FliO Tbd_1609 1 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 74316036 Common - Multi-sensor Signal Transduction Histidine Kinase Tbd_0018 223 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 74316679 Nonpathogen - hypothetical protein Tbd_0661 2 None None None 74316419 Common - 30S ribosomal protein S7 Tbd_0401 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 74317705 Common - putative type IV secretory pathway VirD4 components Tbd_1687 41 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 74317535 Common - DNA mismatch repair protein Tbd_1517 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 74317205 Common - Citrate synthase I Tbd_1187 194 COG0372 GltA, Citrate synthase Energy production and conversion 74318556 Common - zinc/manganese transport system substrate-binding protein Tbd_2538 93 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 74316828 Common - pseudouridine synthase, RluD Tbd_0810 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 74318477 Common - phosphoribosylglycinamide synthetase Tbd_2459 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 74318290 Common - nitrate transporter periplasmic component Tbd_2272 97 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 74317484 Common - hypothetical protein Tbd_1466 56 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 74316293 Nonpathogen - hypothetical protein Tbd_0275 1 None None None 74318482 Common - Two Component Transcriptional Regulator, LuxR family Tbd_2464 222 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 74317988 Common - putative denitrification protein NorE Tbd_1970 144 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 74316150 Nonpathogen - hypothetical protein Tbd_0132 1 None None None 74318222 Common - conserved hypothetical protein containg TPR repeat Tbd_2204 71 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 74316945 Common - hypothetical protein Tbd_0927 7 None None None 74317760 Common - H+-transporting two-sector ATPase, delta/epsilon subunit Tbd_1742 163 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 74318420 Common - preprotein translocase subunit SecB Tbd_2402 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 74318829 Common - hypothetical protein Tbd_2811 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 74317642 Common - CheA Signal Transduction Histidine Kinases (STHK) Tbd_1624 151 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 74317362 Nonpathogen - Transcriptional Regulator, XRE family Tbd_1344 4 COG1476 COG1476, Predicted transcriptional regulators Transcription 74318072 Common - pantoate-beta-alanine ligase Tbd_2054 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 74316054 Common - thioredoxin Tbd_0036 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 74317341 Common - hypothetical protein Tbd_1323 5 None None None 74316769 Nonpathogen - hypothetical protein Tbd_0751 1 None None None 74318562 Nonpathogen - hypothetical protein Tbd_2544 1 COG3439 COG3439, Uncharacterized conserved protein Function unknown 74316110 Common - chaperonin GroES (Hsp10, Cpn10)) Tbd_0092 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 74317391 Nonpathogen - hypothetical protein Tbd_1373 4 None None None 74317830 Common - DNA mismatch endonuclease Tbd_1812 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 74318782 Common - conserved hypothetical membrane-anchored protein Tbd_2764 71 COG2323 COG2323, Predicted membrane protein Function unknown 74318554 Nonpathogen - hypothetical protein Tbd_2536 1 None None None 74318804 Common - Two Component Transcriptional Regulator, LuxR family Tbd_2786 193 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 74316483 Nonpathogen - hypothetical protein Tbd_0465 4 None None None 74318171 Common - Elongator protein 3/MiaB/NifB Tbd_2153 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 74318657 Common cbbR2 transcriptional regulator Tbd_2639 192 COG0583 LysR, Transcriptional regulator Transcription 74316890 Common - adenylylsulfate reductase Tbd_0872 58 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 74316141 Common - cell division transmembrane protein Tbd_0123 80 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 74316360 Common - iron-sulfur cluster-binding protein Tbd_0342 79 COG0348 NapH, Polyferredoxin Energy production and conversion 74318623 Common - Protein of unknown function DUF132 Tbd_2605 4 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 74317839 Common - putative type IV secretory pathway VirD4 component Tbd_1821 54 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 74316186 Common apaH diadenosine tetraphosphatase Tbd_0168 112 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 74318619 Common - hypothetical protein Tbd_2601 94 COG0628 PerM, Predicted permease General function prediction only 74316290 Common - thioredoxin family protein Tbd_0272 157 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 74317274 Common - hypothetical protein Tbd_1256 139 COG1354 COG1354, Uncharacterized conserved protein Function unknown 74316959 Nonpathogen - hypothetical protein Tbd_0941 1 None None None 74317323 Common - hypothetical protein Tbd_1305 77 COG2267 PldB, Lysophospholipase Lipid metabolism 74318286 Common - TonB domain protein Tbd_2268 4 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 74316849 Common - putative phosphoketolase Tbd_0831 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 74317904 Common - possible oxo-acyl acyl carrier protein dehydrogenase Tbd_1886 21 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 74318178 Nonpathogen - hypothetical protein Tbd_2160 1 None None None 74317372 Nonpathogen - hypothetical protein Tbd_1354 1 None None None 74317592 Nonpathogen - hypothetical protein Tbd_1574 4 None None None 74317427 Common - hypothetical protein Tbd_1409 57 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 74318180 Common - hypothetical protein Tbd_2162 44 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 74317509 Common - adenine specific DNA-methyltransferase Tbd_1491 140 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 74317024 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Tbd_1006 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74316760 Common - ADP-heptose--LPS heptosyltransferase II Tbd_0742 88 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 74318675 Common - rhodanese-like protein Tbd_2657 15 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 74317765 Nonpathogen - hypothetical protein Tbd_1747 17 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 74316373 Common - filamentous haemagglutinin-related protein Tbd_0355 53 None None None 74318108 Common - hypothetical protein Tbd_2090 10 None None None 74317154 Common - Periplasmic phosphate binding protein Tbd_1136 110 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 74317076 Nonpathogen - hypothetical protein Tbd_1058 5 None None None 74317722 Common tatA twin argininte translocase protein A Tbd_1704 64 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 74317311 Common - tyep II secretion system protein G Tbd_1293 74 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74318644 Common - glucosyl-glycerol-phosphate synthase Tbd_2626 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 74316606 Common - acetyl-CoA carboxylase, alpha subunit Tbd_0588 209 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 74318588 Common - Two Component Transcriptional Regulator, LuxR family Tbd_2570 174 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 74318524 Common - divalent cation transporter Tbd_2506 172 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 74316107 Common - Exonuclease Tbd_0089 62 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 74317376 Nonpathogen - hypothetical protein Tbd_1358 1 None None None 74316159 Nonpathogen - hypothetical protein Tbd_0141 1 None None None 74317026 Common - initiation factor 3 Tbd_1008 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 74316442 Common - ribosomal protein L15 Tbd_0424 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 74317109 Common - flagella ATPase FliI Tbd_1091 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 74316542 Common - hypothetical protein Tbd_0524 24 None None None 74317889 Common - putative epimerase/dehydratase polysaccharide-related biosynthesis protein Tbd_1871 138 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74317655 Common - flagellar basal-body rod protein FlgB Tbd_1637 65 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 74316810 Common - peptidase M50, putative membrane-associated zinc metallopeptidase Tbd_0792 209 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 74317299 Common - hypothetical protein Tbd_1281 96 COG1262 COG1262, Uncharacterized conserved protein Function unknown 74317597 Nonpathogen - hypothetical protein Tbd_1579 4 COG1531 COG1531, Uncharacterized protein conserved in archaea Function unknown 74318467 Common - ATP-dependent DNA helicase Tbd_2449 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 74316708 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Tbd_0690 100 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 74316714 Common - ribosome-binding factor A Tbd_0696 172 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 74318406 Common - Carbamoyl-phosphate synthase L chain, ATP-binding Tbd_2388 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 74318534 Common - hypothetical protein Tbd_2516 26 COG3014 COG3014, Uncharacterized protein conserved in bacteria Function unknown 74318569 Common - Response regulator receiver domain protein (CheY) Tbd_2551 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74317456 Nonpathogen - hypothetical protein Tbd_1438 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 74317784 Common - Competence protein ComEA Tbd_1766 133 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 74316208 Nonpathogen - hypothetical protein Tbd_0190 6 None None None 74318123 Common rpsF 30S ribosomal protein S6 Tbd_2105 198 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 74316590 Common - DMSO reductase chain C Tbd_0572 19 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 74317944 Common - putative dissimilatory sulfite reductase Tbd_1926 32 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 74318052 Common - putative cytochrome c553 Tbd_2034 39 COG2863 COG2863, Cytochrome c553 Energy production and conversion 74316992 Common - glucose-6-phosphate isomerase Tbd_0974 189 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 74317915 Nonpathogen - putative Outer membrane protein Tbd_1897 8 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74317661 Common - flavin reductase-like protein Tbd_1643 115 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 74317755 Common - putative FAD-dependent dehydrogenase Tbd_1737 81 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 74316281 Common - peptidoglycan glycosyltransferase Tbd_0263 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 74318500 Common - DsrF protein Tbd_2482 37 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 74316238 Common - hypothetical protein Tbd_0220 61 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 74317000 Common - putative Zn-dependent protease containing TPR repeats Tbd_0982 122 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 74316473 Common argC N-acetyl-gamma-glutamyl-phosphate reductase Tbd_0455 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 74317938 Common - 3-isopropylmalate dehydrogenase Tbd_1920 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 74316042 Common - hypothetical protein Tbd_0024 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 74316977 Common - hypothetical protein Tbd_0959 60 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 74318209 Common ribH riboflavin synthase subunit beta Tbd_2191 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 74318081 Common - glucose-6-phosphate isomerase Tbd_2063 197 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 74318453 Common - exodeoxyribonuclease III xth Tbd_2435 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 74316368 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Tbd_0350 166 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 74316627 Common - RNA methyltransferase TrmH Tbd_0609 214 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 74317670 Common - inorganic pyrophosphatase Tbd_1652 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 74316668 Common - hypothetical protein Tbd_0650 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 74316572 Nonpathogen - hypothetical protein Tbd_0554 1 None None None 74317353 Common - heavy metal RND efflux outer membrane protein, CzcC family Tbd_1335 41 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74316266 Common - ABC transporter, ATP-binding protein Tbd_0248 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 74318632 Common - universal stress protein Tbd_2614 136 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 74317858 Nonpathogen - hypothetical protein Tbd_1840 7 None None None 74317462 Nonpathogen - hypothetical protein Tbd_1444 1 None None None 74316757 Common - ABC transport protein ATPase component Tbd_0739 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 74318386 Common - prepilin cysteine protease (C20) PilD Tbd_2368 113 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 74318319 Common - Transcriptional Regulator, GntR family Tbd_2301 129 COG2188 PhnF, Transcriptional regulators Transcription 74316888 Nonpathogen - hypothetical protein Tbd_0870 1 None None None 74316049 Common - hypothetical protein Tbd_0031 8 None None None 74317438 Common - Periplasmic phosphate binding protein Tbd_1420 124 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 74316930 Common - biopolymer transport protein ExbD/TolR Tbd_0912 77 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 74317851 Common - ubiquinol-cytochrome c reductase, iron-sulfur subunit Tbd_1833 90 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 74317880 Common - hypothetical protein Tbd_1862 4 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 74316784 Nonpathogen - conserved hypothetical protein containing TPR repeat Tbd_0766 5 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 74317572 Common - hypothetical protein Tbd_1554 8 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 74316444 Common infA translation initiation factor IF-1 Tbd_0426 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 74318029 Common - HAD-superfamily hydrolase Tbd_2011 72 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 74318507 Common - 3-mercaptopyruvate sulfurtransferase Tbd_2489 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 74318384 Common - hypothetical protein Tbd_2366 44 COG4582 COG4582, Uncharacterized protein conserved in bacteria Function unknown 74316625 Common - adenylosuccinate synthetase Tbd_0607 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 74317285 Common - putative transmembrane protein Tbd_1267 16 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 74316136 Common - cell division protein FtsW Tbd_0118 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 74316591 Common - rhodanese-like protein Tbd_0573 171 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 74317716 Common - putative squalene/phytoene dehydrogenase Tbd_1698 35 COG3349 COG3349, Uncharacterized conserved protein Function unknown 74316746 Common - Holo-acyl carrier protein synthase Tbd_0728 84 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 74316836 Common - hypothetical protein Tbd_0818 9 COG4944 COG4944, Uncharacterized protein conserved in bacteria Function unknown 74316825 Common - NAD+ synthase (glutamine-hydrolyzing) Tbd_0807 219 COG0171 NadE, NAD synthase Coenzyme metabolism 74317585 Nonpathogen - hypothetical protein Tbd_1567 1 None None None 74317127 Common - cyclopropane-fatty-acyl-phospholipid synthase Tbd_1109 130 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 74318831 Common - hypothetical protein Tbd_2813 97 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 74317049 Common - hypothetical protein Tbd_1031 114 COG2353 COG2353, Uncharacterized conserved protein Function unknown 74317971 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_1953 181 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 74318136 Common - thioredoxin Tbd_2118 153 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 74317560 Common - DNA polymerase III delta prime subunit Tbd_1542 214 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 74316530 Common - putative modulator of DNA gyrase Tbd_0512 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 74316084 Common - GreA/GreB family elongation factor Tbd_0066 66 COG0782 GreA, Transcription elongation factor Transcription 74317707 Nonpathogen - hypothetical protein Tbd_1689 1 None None None 74318115 Nonpathogen - hypothetical protein Tbd_2097 1 None None None 74317556 Common - molecular chaperone protein DnaK Tbd_1538 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 74318069 Common - 7,8-Dihydro-6-hydroxymethylpterin-pyrophosphokinase, HPPK Tbd_2051 193 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 74318712 Common - thiamine biosynthesis protein ThiC Tbd_2694 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 74316964 Common - 3-demethylubiquinone-9 3-methyltransferase Tbd_0946 186 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 161899034 Common kgd alpha-ketoglutarate decarboxylase Tbd_1188 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 74318098 Common secF preprotein translocase subunit SecF Tbd_2080 205 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 74316840 Common - nitric oxide reductase, cytochrome c-containing subunit Tbd_0822 41 COG3474 COG3474, Cytochrome c2 Energy production and conversion 74317089 Nonpathogen - hypothetical protein Tbd_1071 4 COG0496 SurE, Predicted acid phosphatase General function prediction only 74317803 Nonpathogen - hypothetical protein Tbd_1785 3 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 74318032 Common - hypothetical protein Tbd_2014 117 COG1959 COG1959, Predicted transcriptional regulator Transcription 74318193 Common - hypothetical protein Tbd_2175 19 COG4309 COG4309, Uncharacterized conserved protein Function unknown 74316794 Common - N-acetyl-anhydromuranmyl-L-alanine amidase Tbd_0776 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 74318838 Common - hypothetical protein Tbd_2820 36 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 74316323 Common - glycosyltransferase Tbd_0305 12 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74318820 Common - F0F1 ATP synthase subunit C Tbd_2802 60 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 74316120 Common - hypothetical protein Tbd_0102 18 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 74318059 Nonpathogen - hypothetical protein Tbd_2041 2 None None None 74318158 Common - probable magnesium and cobalt transport transmembrane protein Tbd_2140 152 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 74316074 Common - Predicted signal transduction protein containing EAL and modified HD-GYP domains Tbd_0056 43 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 74318515 Common - HPr kinase Tbd_2497 13 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 74318335 Common - rubrerythrin/nigerythrin-like protein Tbd_2317 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 74316222 Common - type IV pilus assembly membrane transmembrane protein Tbd_0204 48 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 74316548 Common - HPr kinase/phosphorylase Tbd_0530 83 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 74316565 Common - ATPase, type IV pilus assembly protein PilB Tbd_0547 208 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 74317140 Common - probable substrate-binding periplasmic (PBP) ABC transporter protein Tbd_1122 148 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 74317197 Nonpathogen - hypothetical protein Tbd_1179 1 None None None 74316585 Common - sulfur oxidation protein SoxX Tbd_0567 10 None None None 74316297 Common - putative ferredoxin 2fe-2s protein Tbd_0279 83 COG3411 COG3411, Ferredoxin Energy production and conversion 74316187 Common - phospholipid/glycerol acyltransferase Tbd_0169 115 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 74317806 Nonpathogen - hypothetical protein Tbd_1788 1 COG3379 COG3379, Uncharacterized conserved protein Function unknown 74317514 Common - recombination factor protein RarA Tbd_1496 242 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 74318688 Common - Metal dependent phosphohydrolase, HD region Tbd_2670 181 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 74317515 Common - outer membrane lipoprotein carrier protein LolA Tbd_1497 88 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 74318390 Common - transmembrane protein Tbd_2372 56 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 74316722 Common - bacterioferritin Tbd_0704 109 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 74317762 Common - Histidine Kinase Tbd_1744 209 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 74316893 Nonpathogen - hypothetical protein Tbd_0875 1 None None None 74316485 Nonpathogen - probable ABC transporter permease protein Tbd_0467 1 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 74318157 Common - putative lipopolysaccharide core biosynthesis glycosyl transferase protein Tbd_2139 195 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74318417 Common - rhodanese-like protein Tbd_2399 184 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 74316347 Common - hypothetical protein Tbd_0329 6 None None None 74318694 Nonpathogen - hypothetical protein Tbd_2676 1 None None None 74316253 Common - rhodanese-like protein Tbd_0235 49 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 74318251 Common - putative bacterioferritin (cytochrome b1) Tbd_2233 74 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 74316566 Common - hypothetical protein containing TPR repeat Tbd_0548 9 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 74317331 Common - hypothetical protein Tbd_1313 26 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 74317621 Common - flagellar biosynthesis/type III secretory pathway ATPase FliI Tbd_1603 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 74318626 Nonpathogen - hypothetical protein Tbd_2608 1 None None None 74318273 Nonpathogen - hypothetical protein Tbd_2255 1 None None None 74318350 Common - ubiquinone biosynthesis hydroxylase Tbd_2332 121 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 74316550 Common - Possible Sigma 54 modulation protein/ribosomal protein S30EA Tbd_0532 124 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 74316085 Nonpathogen - hypothetical protein Tbd_0067 2 None None None 74318410 Common - peptidase S41A, protease Tbd_2392 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 74317411 Common - ABC transporter transmembrane protein Tbd_1393 36 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 74317329 Common mdoG glucan biosynthesis protein G Tbd_1311 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 74317968 Nonpathogen - hypothetical protein Tbd_1950 2 None None None 74317336 Common - probable integrase/recombinase protein Tbd_1318 26 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 74317879 Common - hypothetical protein Tbd_1861 3 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 74317726 Common - imidazole glycerol phosphate synthase subunit HisF Tbd_1708 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 74316587 Common - Molybdopterin cofactor biosynthesis MoaC region Tbd_0569 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 74317261 Common - flagellar motor protein MotA Tbd_1243 120 COG1291 MotA, Flagellar motor component Cell motility and secretion 74318571 Nonpathogen - hypothetical protein Tbd_2553 8 None None None 74317746 Common - Nucleotide binding protein Tbd_1728 190 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 74318724 Common - tRNA-i(6)A37 modification enzyme MiaB Tbd_2706 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 74316059 Common - hypothetical protein Tbd_0041 20 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 74317179 Common - RNA methyltransferase TrmH, group 1 Tbd_1161 164 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 74316261 Nonpathogen - hypothetical protein Tbd_0243 1 None None None 74316210 Nonpathogen - hypothetical protein Tbd_0192 1 None None None 74316066 Common - hypothetical protein Tbd_0048 23 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 74318168 Common - TRAP transporter, small subunit Tbd_2150 69 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 74317848 Common - stringent starvation protein a Tbd_1830 116 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 74317492 Common - phospholipase D/Transphosphatidylase Tbd_1474 84 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 74316820 Common - Ca2+:cation antiporter, CaCA family Tbd_0802 40 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 74318149 Common - putative dissimilatory sulfite reductase Tbd_2131 14 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 74317207 Common - dihydrolipoamide succinyltransferase Tbd_1189 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 74317578 Common - protease Tbd_1560 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 74317759 Common - putative tetrathionate reductase, subunit A Tbd_1741 97 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 74317924 Nonpathogen - hypothetical protein Tbd_1906 1 None None None 74316975 Common - integration host factor, beta subunit Tbd_0957 209 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 74318026 Common - ATP-dependent helicase HrpA Tbd_2008 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 74316508 Common - stomatin-like transmembrane protein, Band 7 protein Tbd_0490 209 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 74317445 Common - putative permease Tbd_1427 79 COG0701 COG0701, Predicted permeases General function prediction only 74318613 Common - hypothetical protein Tbd_2595 138 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 74318778 Common - phospholipid/glycerol acyltransferase Tbd_2760 66 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 74318305 Common - putative integral membrane protein Tbd_2287 40 COG3647 COG3647, Predicted membrane protein Function unknown 74318175 Common - hypothetical protein Tbd_2157 44 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 74316926 Common - possible signal peptide protein Tbd_0908 14 None None None 74316142 Common - Cell division protein FtsA Tbd_0124 197 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 74316105 Common - hypothetical protein Tbd_0087 56 COG4327 COG4327, Predicted membrane protein Function unknown 74317416 Common - putative cytochrome c-type protein Tbd_1398 43 COG3245 CycB, Cytochrome c5 Energy production and conversion 74316953 Common - hypothetical protein Tbd_0935 12 None None None 74318404 Common - hypothetical protein Tbd_2386 151 COG1610 COG1610, Uncharacterized conserved protein Function unknown 74316218 Common - hypothetical protein Tbd_0200 25 None None None 74317361 Nonpathogen - hypothetical protein Tbd_1343 1 None None None 74318781 Common - oxidoreductase, FAD-binding, putative Tbd_2763 42 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 74316135 Common - UDP-N-acetylmuramoylalanine-D-glutamate ligase Tbd_0117 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 74316412 Common rplK 50S ribosomal protein L11 Tbd_0394 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 74318005 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Tbd_1987 150 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 74318142 Common - multiple antibiotic resistance (MarC)-related proteins Tbd_2124 112 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 74317254 Common - ATP-dependent Clp protease adaptor protein ClpS Tbd_1236 116 COG2127 COG2127, Uncharacterized conserved protein Function unknown 74316438 Common rplF 50S ribosomal protein L6 Tbd_0420 239 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 74318768 Common - hypothetical protein Tbd_2750 25 COG4258 COG4258, Predicted exporter General function prediction only 74318323 Common - hypothetical protein Tbd_2305 21 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 74318639 Common cbbO1 rubisco activation protein CbbO Tbd_2621 48 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 74316745 Common - beta-hexosaminidase Tbd_0727 179 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 74317499 Common - putative phage DNA polymerase Tbd_1481 148 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 74318375 Nonpathogen - hypothetical protein Tbd_2357 1 None None None 74317370 Nonpathogen - hypothetical protein Tbd_1352 1 None None None 74316286 Common - hypothetical protein Tbd_0268 55 COG2921 COG2921, Uncharacterized conserved protein Function unknown 74317609 Common - putative flagellar protein FlaG Tbd_1591 25 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 74316094 Common - hypothetical protein Tbd_0076 17 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 74317882 Common - pilus assembly protein Tbd_1864 27 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 74317906 Common - hypothetical protein Tbd_1888 3 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 74316382 Common - hypothetical protein Tbd_0364 9 None None None 74317481 Common - translation initiation factor IF-1 Tbd_1463 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 74318496 Common - reductase, iron-sulfur binding subunit, putative Tbd_2478 47 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 74316906 Common - hypothetical protein Tbd_0888 6 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 74317007 Common - iron transport system permease protein Tbd_0989 142 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 74316468 Common - hypothetical protein Tbd_0450 7 COG5428 COG5428, Uncharacterized conserved small protein Function unknown 74318240 Common - indole-3-glycerol phosphate synthase Tbd_2222 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 74317797 Common - glucose-1-phosphate thymidylyltransferase, long form Tbd_1779 232 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 74317168 Common nuoI NADH dehydrogenase subunit I Tbd_1150 188 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 74317860 Common - GTPase EngC Tbd_1842 163 COG1162 COG1162, Predicted GTPases General function prediction only 74316060 Common - molybdopterin-guanine dinucleotide biosynthesis protein A Tbd_0042 82 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 74317063 Common - hypothetical protein Tbd_1045 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 74317248 Common - extracellular solute-binding protein, family 3 Tbd_1230 93 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 74318217 Common - conserved hypothetical protein containing TPR repeat Tbd_2199 38 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 74316517 Common - mechanosensitive ion channel Tbd_0499 135 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 74316651 Common - hypothetical protein Tbd_0633 12 None None None 74317540 Common - glutamate racemase Tbd_1522 191 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 74317683 Common - hydroxyacylglutathione hydrolase Tbd_1665 163 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 74318099 Common - putative integral membrane protein dedA-like protein Tbd_2081 163 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 74318249 Common apaG ApaG Tbd_2231 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 74318364 Common - D,D-heptose 1,7-bisphosphate phosphatase Tbd_2346 127 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 74316436 Common rpsN 30S ribosomal protein S14 Tbd_0418 206 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 74316532 Common - phospho-2-dehydro-3-heoxyheptonate aldolase Tbd_0514 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 74317013 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Tbd_0995 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74318201 Common - hypothetical protein Tbd_2183 33 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 74316910 Nonpathogen - hypothetical protein Tbd_0892 5 None None None 74317432 Common - Secretion protein HlyD Tbd_1414 145 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 74317319 Common - type II secretion system protein Tbd_1301 14 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74317241 Common - hypothetical protein Tbd_1223 14 COG3565 COG3565, Predicted dioxygenase of extradiol dioxygenase family General function prediction only 74318594 Common - TonB-like protein Tbd_2576 35 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 74317953 Nonpathogen - hypothetical protein Tbd_1935 1 None None None 74317383 Common - sulfite reductase, dissimilatory-type, gamma subunit Tbd_1365 51 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 74317997 Common - tryptophan repressor binding protein Tbd_1979 111 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 74318733 Common - threonine-phosphate decarboxylase Tbd_2715 144 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 74316819 Common - hypothetical protein Tbd_0801 4 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 74318495 Common - putative glutamate synthase (NADPH) small subunit Tbd_2477 190 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 74318227 Common - MotA/TolQ/ExbB proton channel family Tbd_2209 143 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 74318669 Common cbbR3 transcriptional regulator Tbd_2651 193 COG0583 LysR, Transcriptional regulator Transcription 74317405 Common - membrane protein Tbd_1387 30 COG4244 COG4244, Predicted membrane protein Function unknown 74317972 Common - hypothetical protein Tbd_1954 2 None None None 74317100 Common - ABC-2 type transport system permease protein Tbd_1082 141 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 74316324 Common - arylsulfatase Tbd_0306 90 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 74316800 Nonpathogen - hypothetical protein Tbd_0782 1 None None None 74316544 Common - aromatic acid decarboxylase Tbd_0526 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 74316740 Common - TonB-dependent siderophore receptor Tbd_0722 127 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 74316339 Common - BioH Tbd_0321 52 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 74318791 Nonpathogen - hypothetical protein Tbd_2773 1 None None None 74317099 Common - hypothetical protein Tbd_1081 65 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 74316658 Common - Cytochrome c oxidase cbb3-type, subunit III Tbd_0640 79 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 74317476 Common - hypothetical protein Tbd_1458 56 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 74317696 Common - trigger factor Tbd_1678 211 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 74316032 Common - formylmethionine deformylase Tbd_0014 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 74316770 Common - pilus assembly pathway ATPase PilB Tbd_0752 222 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 74316735 Common - diaminopimelate decarboxylase Tbd_0717 213 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 74316889 Nonpathogen - hypothetical protein Tbd_0871 11 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 74316635 Common - hypothetical protein Tbd_0617 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 74318470 Common - hypothetical protein Tbd_2452 129 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 74318192 Common - hypothetical protein Tbd_2174 17 None None None 74316374 Common - 5'-nucleotidase Tbd_0356 129 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 74318219 Common - probable transmembrane protein Tbd_2201 49 COG2391 COG2391, Predicted transporter component General function prediction only 74317233 Common - integron integrase Tbd_1215 221 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 74317309 Common - conserved hypothetical protein containing twin-arginine translocation pathway signal Tbd_1291 25 None None None 74316694 Common - putative ATP-dependent protease LA, putative Tbd_0676 97 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 74318543 Common - hypothetical protein Tbd_2525 137 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 74317577 Nonpathogen - Transcriptional antiterminator, Rof Tbd_1559 1 COG4568 Rof, Transcriptional antiterminator Transcription 74316835 Nonpathogen - hypothetical protein Tbd_0817 3 None None None 74316734 Common - putative aldolase Tbd_0716 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 74316876 Common - DNA polymerase III, alpha subunit Tbd_0858 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 74317303 Common - molybdate ABC transporter, ATP-binding protein Tbd_1285 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 74316880 Common - hypothetical protein Tbd_0862 23 COG3369 COG3369, Uncharacterized conserved protein Function unknown 74316670 Common - Pyruvate/2-oxoglutarate dehydrogenase complex dihydrolipoamide dehydrogenase E3 component Tbd_0652 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 74318277 Common - hypothetical protein Tbd_2259 16 None None None 74316661 Common - Cytochrome c oxidase cbb3-type, subunit I Tbd_0643 150 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 74318618 Common - hypothetical protein Tbd_2600 13 COG3223 COG3223, Predicted membrane protein Function unknown 74318345 Common - putative sulfite reductase Tbd_2327 58 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 74316944 Common - hypothetical protein Tbd_0926 5 None None None 74317546 Common - phosphoesterase PHP Tbd_1528 118 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 74318090 Nonpathogen - hypothetical protein Tbd_2072 1 None None None 74317091 Nonpathogen - hypothetical protein Tbd_1073 1 None None None 74318580 Common - putative oxidoreductase protein Tbd_2562 67 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74316985 Common - ribonuclease BN Tbd_0967 42 COG1295 Rbn, Predicted membrane protein Function unknown 74318446 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Tbd_2428 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74316305 Common - polysaccharide deacetylase Tbd_0287 100 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 74318557 Common - zinc/manganese transport system permease protein Tbd_2539 5 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 74317979 Common - hypothetical protein Tbd_1961 17 COG3668 ParE, Plasmid stabilization system protein General function prediction only 74317700 Common - nuclease (SNase-like) Tbd_1682 83 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 74317050 Common - hypothetical protein Tbd_1032 90 COG2353 COG2353, Uncharacterized conserved protein Function unknown 74318621 Common - heat shock protein HtpX Tbd_2603 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 74317558 Common - TatD-related deoxyribonuclease Tbd_1540 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 74317211 Common - Multi-sensor Signal Transduction Histidine Kinase Tbd_1193 221 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 74317856 Common - hypothetical protein Tbd_1838 3 COG3746 OprP, Phosphate-selective porin Inorganic ion transport and metabolism 74318389 Common - probable transmembrane protein Tbd_2371 213 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 74316449 Common - ribosomal protein L17 Tbd_0431 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 74318082 Common - nucleoside-diphosphate-sugar epimerase (UDP-glucose 4-epimerase) Tbd_2064 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74316256 Common - hypothetical protein Tbd_0238 49 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 74317566 Common - Acyl carrier protein (ACP) Tbd_1548 208 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 74318016 Common - oxidoreductase, FAD-binding Tbd_1998 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 74318134 Nonpathogen - hypothetical protein Tbd_2116 4 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74316299 Common - polysaccharide export outer membrane protein Tbd_0281 89 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 74318822 Nonpathogen - hypothetical protein Tbd_2804 1 None None None 74316692 Common - major facilitator superfamily protein Tbd_0674 198 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 74317510 Common - type III restriction-modification enzyme helicase subunit Tbd_1492 33 COG3587 COG3587, Restriction endonuclease Defense mechanisms 74317022 Common - 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Tbd_1004 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 74317704 Common - putative ATP-dependent exoDNAse (exonuclease V) alpha subunit Tbd_1686 95 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 74317845 Nonpathogen - hypothetical protein Tbd_1827 1 None None None 74316939 Common - peptide chain release factor 2 Tbd_0921 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 74316608 Common - nucleoside diphosphate kinase Tbd_0590 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 74316862 Common - threonine synthase Tbd_0844 139 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 74317267 Common - RNA polymerase sigma-70 factor Tbd_1249 211 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 74317047 Common - probable cytochrome b561 Tbd_1029 86 COG3038 CybB, Cytochrome B561 Energy production and conversion 74317758 Common - putative tetrathionate reductase subunit C Tbd_1740 24 COG4881 COG4881, Predicted membrane protein Function unknown 74316348 Common - cytochrome c oxidase, subunit III Tbd_0330 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 74316759 Common - histidinol-phosphate phosphatase Tbd_0741 119 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 74316966 Common - DNA gyrase subunit A Tbd_0948 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 74317260 Common - hypothetical protein Tbd_1242 23 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 74317003 Nonpathogen - hypothetical protein Tbd_0985 1 COG4360 APA2, ATP adenylyltransferase (5',5'''-P-1,P-4-tetraphosphate phosphorylase II) Nucleotide transport and metabolism 74317800 Common - hypothetical protein Tbd_1782 18 None None None 74316936 Common - sulfur oxidation protein SoxA Tbd_0918 27 COG3258 COG3258, Cytochrome c Energy production and conversion 74317199 Common - malate dehydrogenase (oxaloacetate-decarboxylating) Tbd_1181 202 COG0281 SfcA, Malic enzyme Energy production and conversion 74316233 Common - ubiquinone/menaquinone biosynthesis methyltransferase Tbd_0215 195 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 74317517 Common - hypothetical protein Tbd_1499 22 None None None 74316311 Common - glycosyl transferase, group 1 Tbd_0293 221 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74316989 Common - hypothetical protein Tbd_0971 30 COG3298 COG3298, Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA replication, recombination, and repair 74317862 Common - conserved hypothetical protein containing CBS domain Tbd_1844 145 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 74317833 Nonpathogen - hypothetical protein Tbd_1815 1 None None None 74318616 Common - putative tRNA and rRNA cytosine-C5-methylase Tbd_2598 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 74316366 Common - Two component Transcriptional regulator, Winged helix family Tbd_0348 196 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74316574 Common - iron-sulfur cluster-binding protein Tbd_0556 85 COG0348 NapH, Polyferredoxin Energy production and conversion 74318458 Common - Iojap-related protein Tbd_2440 199 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 74316127 Common - dihydroorotase Tbd_0109 86 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 74318034 Common - electron transport complex protein RnfB Tbd_2016 131 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 74316083 Common - hypothetical protein Tbd_0065 143 COG2510 COG2510, Predicted membrane protein Function unknown 74316264 Common - homoserine O-succinyltransferase Tbd_0246 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 74316125 Common - phosphoheptose isomerase Tbd_0107 121 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 74316221 Common - type IV pilus assembly protein PilN Tbd_0203 45 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 74316333 Common - 3-dehydroquinate synthase Tbd_0315 210 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 74317142 Common - hypothetical protein Tbd_1124 64 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 74317460 Common - hypothetical protein Tbd_1442 11 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74318653 Common - hypothetical protein Tbd_2635 18 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 74316850 Common - acetate kinase Tbd_0832 161 COG0282 ackA, Acetate kinase Energy production and conversion 74316871 Common - pseudouridine synthase, Rsu Tbd_0853 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 74317216 Common - hypothetical protein Tbd_1198 6 None None None 74318066 Common - putative transmembrane ABC transporter permease Tbd_2048 177 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 74317347 Common - probable cobalt-zinc-cadmium outer membrane resistance protein Tbd_1329 53 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74317355 Common - hypothetical protein Tbd_1337 27 COG1742 COG1742, Uncharacterized conserved protein Function unknown 74317301 Common - molybdenum ABC transporter, periplasmic binding protein Tbd_1283 119 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 74316024 Common - hypothetical protein Tbd_0006 13 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 74317712 Nonpathogen - hypothetical protein Tbd_1694 2 None None None 74316171 Common - ABC transport system periplasmic component Tbd_0153 12 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 74318710 Common - undecaprenyl kinase, bacitracin resistance protein BacA Tbd_2692 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 74317224 Common - hypothetical protein Tbd_1206 78 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 74316283 Common - rare lipoprotein A Tbd_0265 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 74318649 Common - methionine sulfoxide reductase B Tbd_2631 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 74316997 Nonpathogen - hypothetical protein Tbd_0979 6 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 74316461 Common - hypothetical protein Tbd_0443 13 COG4390 COG4390, Uncharacterized protein conserved in bacteria Function unknown 74317982 Nonpathogen - hypothetical protein Tbd_1964 2 None None None 74317468 Nonpathogen - hypothetical protein Tbd_1450 1 None None None 74316301 Common - protein-tyrosine kinase Tbd_0283 128 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 74318642 Common rbcL ribulose bisophosphate carboxylase Tbd_2624 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 74316666 Nonpathogen - hypothetical protein Tbd_0648 4 COG3462 COG3462, Predicted membrane protein Function unknown 74318662 Common - Carboxysome structural peptide CsoS1B Tbd_2644 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 74316795 Common - hypoxanthine-guanine phosphoribosyltransferase Tbd_0777 151 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 74316479 Common - Putative transcriptional acitvator, Baf Tbd_0461 114 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 74317381 Common - putative GTP-binding protein Tbd_1363 216 COG2262 HflX, GTPases General function prediction only 74317287 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) and Response Regulator Receiver modulation Tbd_1269 223 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74316472 Common rpsI 30S ribosomal protein S9 Tbd_0454 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 74316052 Common - hypothetical protein Tbd_0034 20 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 74316475 Common anmK anhydro-N-acetylmuramic acid kinase Tbd_0457 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 74318260 Nonpathogen - hypothetical protein Tbd_2242 1 None None None 74316882 Common - ribosomal protein L21 Tbd_0864 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 74317970 Nonpathogen - hypothetical protein Tbd_1952 1 None None None 74318719 Common - pteridine reductase Tbd_2701 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 74316145 Common - outer membrane protein Tbd_0127 168 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 74318518 Common - Two Component Transcriptional Regulator, Fis family Tbd_2500 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 74318596 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Tbd_2578 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74317637 Common - chemotaxis sensory transducer Tbd_1619 140 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 74317504 Common - hypothetical protein Tbd_1486 2 None None None 74316497 Common - coproporphyrinogen III oxidase Tbd_0479 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 74316782 Common - general secretion pathway protein D Tbd_0764 139 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 74316423 Common - ribosomal protein L3 Tbd_0405 237 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 74318542 Common - hypothetical protein Tbd_2524 78 COG0456 RimI, Acetyltransferases General function prediction only 74317478 Nonpathogen - hypothetical protein Tbd_1460 3 COG4831 COG4831, Uncharacterized conserved protein Function unknown 74317471 Common - glutathione synthase/ribosomal protein S6 modification enzyme (glutaminyl transferase) Tbd_1453 31 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 74317667 Nonpathogen - hypothetical protein Tbd_1649 1 None None None 74317946 Common - flagellar biosynthesis switch protein Tbd_1928 232 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 74317234 Common - probable cytosine/adenosine deaminase Tbd_1216 209 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 74316847 Common - hypothetical protein Tbd_0829 59 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 74316452 Nonpathogen - probable lipoprotein Tbd_0434 1 None None None 74317825 Common - Two Component Transcriptional Regulator, Fis family Tbd_1807 174 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 74317291 Common - ABC-type transport system ATPase Tbd_1273 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 74316711 Common - polynucleotide phosphorylase/polyadenylase Tbd_0693 238 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 74317326 Common - hypothetical protein Tbd_1308 58 COG5483 COG5483, Uncharacterized conserved protein Function unknown 74317786 Nonpathogen - hypothetical protein Tbd_1768 4 None None None 74317779 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Tbd_1761 180 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 74317829 Common - hypothetical protein Tbd_1811 5 None None None 74316762 Common - hypothetical protein Tbd_0744 32 COG3652 COG3652, Predicted outer membrane protein Function unknown 74316593 Common - hypothetical protein Tbd_0575 41 COG2210 COG2210, Uncharacterized conserved protein Function unknown 74318186 Common - Riboflavin biosynthesis protein RibD diaminohydroxyphosphoribosylaminopyrimid ine deaminase + 5-amino-6-(5- phosphoribosylamino)uracil reductase oxidoreductase protein Tbd_2168 223 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 74316523 Nonpathogen - hypothetical protein Tbd_0505 3 None None None 74317657 Common - Putative Anti-Sigma-28 factor, FlgM Tbd_1639 20 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 74317714 Common - putative phytoene synthase-like protein Tbd_1696 97 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 74318783 Common - hypothetical protein Tbd_2765 6 None None None 74318802 Common - thiol:disulfide interchange protein DsbA Tbd_2784 67 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 74316869 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Tbd_0851 213 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 74317583 Common - Protein tyrosine phosphatase Tbd_1565 145 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 74318549 Common - probable transmembrane drug efflux protein Tbd_2531 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 74316502 Common - hypothetical protein Tbd_0484 50 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 74317313 Common - type II secretion system protein Tbd_1295 220 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 74317890 Common - putative undecaprenyl phosphate N-acetylglucosaminyltransferase Tbd_1872 47 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 74317774 Common smpB SsrA-binding protein Tbd_1756 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 74316440 Common rpsE 30S ribosomal protein S5 Tbd_0422 248 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 74316151 Nonpathogen - hypothetical protein Tbd_0133 1 None None None 74318532 Common - putative lipoprotein Tbd_2514 29 COG3417 FlgN, Collagen-binding surface adhesin SpaP (antigen I/II family) General function prediction only 74316206 Common - GTP-binding Tbd_0188 181 COG0218 COG0218, Predicted GTPase General function prediction only 74317614 Common - flagellar protein FhlB Tbd_1596 79 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 74316618 Nonpathogen - hypothetical protein Tbd_0600 2 None None None 74318347 Common - flavohemoglobin Tbd_2329 140 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 74316702 Common - hypothetical protein Tbd_0684 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 74316356 Common - Cytochrome c oxidase cbb3-type, subunit I Tbd_0338 148 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 74316707 Common - methylenetetrahydrofolate cyclohydrolase Tbd_0689 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 74316319 Common - glycosyltransferase Tbd_0301 217 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 74316131 Common - peptidoglycan glycosyltransferase Tbd_0113 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 74318609 Common - hemin receptor precursor, TonB-dependent outer membrane uptake protein Tbd_2591 125 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 74316538 Common greB transcription elongation factor GreB Tbd_0520 198 COG0782 GreA, Transcription elongation factor Transcription 74318624 Common - putative thioredoxin-like protein Tbd_2606 230 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 74318469 Common - hypothetical protein Tbd_2451 11 None None None 74316743 Common - hypothetical protein Tbd_0725 6 COG4256 HemP, Hemin uptake protein Inorganic ion transport and metabolism 74317606 Common - Two Component Transcriptional Regulator, LuxR family Tbd_1588 204 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 74316189 Common - carbohydrate kinase, PfkB family Tbd_0171 164 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 74317045 Common - molybdenum cofactor biosynthesis protein E Tbd_1027 160 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 74316511 Common - multisubunit Na+/H+ antiporter, subunit F Tbd_0493 76 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 74317595 Common - putative NADH-dependent flavin oxidoreductase Tbd_1577 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 74318750 Nonpathogen - hypothetical protein Tbd_2732 13 None None None 74316904 Common - putative thioredoxin protein Tbd_0886 207 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 74317247 Common - seryl-tRNA synthetase, class IIa Tbd_1229 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 74317817 Common - long-chain fatty acid transport protein Tbd_1799 17 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 74318079 Common - glucose-1-phosphate adenylyltransferase Tbd_2061 182 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 74318121 Common rpsR 30S ribosomal protein S18 Tbd_2103 173 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 74317392 Nonpathogen - membrane-bound hydrogenase component hupE Tbd_1374 1 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 74316040 Common - trk system potassium uptake membrane protein Tbd_0022 131 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 74316295 Common - ABC-2 type transporter ATPase Tbd_0277 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 74318297 Common - Histidine Kinase Tbd_2279 209 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74316629 Common - Protein of unknown function RIO1 Tbd_0611 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 74316620 Common - GTP-binding protein HflX Tbd_0602 210 COG2262 HflX, GTPases General function prediction only 74317276 Common - pseudouridine synthase, Rsu Tbd_1258 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 74317677 Common - probable copper ion binding protein Tbd_1659 123 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 74317107 Common - flagellar motor switch protein FliG Tbd_1089 111 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 74316116 Common - UDP-glucose/GDP-mannose dehydrogenase Tbd_0098 205 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 74317123 Common - methionine sulfoxide reductase B Tbd_1105 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 74317396 Common - Ni-Fe hydrogenase, small subunit Tbd_1378 78 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 74317155 Common - phosphate ABC transporter, permease protein PstC Tbd_1137 224 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 74317897 Common - putative dehydratase RfbH Tbd_1879 196 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 74318488 Common - hypothetical protein Tbd_2470 9 None None None 74317080 Nonpathogen - hypothetical protein Tbd_1062 2 None None None 74316359 Common - Cytochrome c oxidase cbb3-type, subunit III Tbd_0341 84 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 74316640 Common - septum formation initiator protein Tbd_0622 62 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 74318465 Common cbbP phosphoribulokinase Tbd_2447 56 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 74317422 Common - nitrate reductase, beta subunit Tbd_1404 141 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 74316509 Common - probable transmembrane protein Tbd_0491 74 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 74318070 Common - deoxynucleoside kinase Tbd_2052 39 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 74317131 Common - hypothetical protein Tbd_1113 15 None None None 74316180 Common pykA pyruvate kinase Tbd_0162 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 74318700 Common - putative restriction endonuclease S subunit Tbd_2682 75 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 74318591 Nonpathogen - hypothetical protein Tbd_2573 1 None None None 74317034 Nonpathogen - hypothetical protein Tbd_1016 1 None None None 74318709 Common - glycerophosphoryl diester phosphodiesterase family protein Tbd_2691 47 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 74317292 Common - putative integral membrane protein Tbd_1274 87 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 74317113 Common fliP flagellar biosynthesis protein FliP Tbd_1095 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 74317645 Common flgL flagellar hook-associated protein FlgL Tbd_1627 103 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 74318151 Common - putative ribonuclease I Tbd_2133 47 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 74318647 Common - predicted inner membrane peptidase Tbd_2629 187 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 74316766 Common - hypothetical protein Tbd_0748 39 COG0714 COG0714, MoxR-like ATPases General function prediction only 74316680 Common - acetolactate synthase large subunit Tbd_0662 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 74317073 Common - S-adenosylmethionine-dependent methyltransferase Tbd_1055 99 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 74318814 Common atpC F0F1 ATP synthase subunit epsilon Tbd_2796 175 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 74316167 Common - lipoprotein, putative Tbd_0149 12 COG5608 COG5608, Conserved secreted protein Function unknown 74316160 Common - Secretion protein HlyD Tbd_0142 107 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 74317690 Common - enoyl-(acyl carrier protein) reductase Tbd_1672 232 COG0623 FabI, Enoyl- acyl-carrier-protein 74317288 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase Tbd_1270 215 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 74318042 Common - long-chain fatty-acid-CoA ligase Tbd_2024 161 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 74317508 Common - hypothetical protein Tbd_1490 13 None None None 74316672 Common - pyruvate dehydrogenase E1 beta subunit Tbd_0654 178 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 74317575 Common - Maf-like protein Tbd_1557 180 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 74316884 Common obgE GTPase ObgE Tbd_0866 230 COG0536 Obg, Predicted GTPase General function prediction only 74316380 Common - hypothetical protein Tbd_0362 6 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 74316428 Common - ribosomal protein L22 Tbd_0410 221 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 74317120 Common - hypothetical protein Tbd_1102 7 None None None 74316395 Common - insulinase family protein Tbd_0377 199 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 74317221 Common - hypothetical protein Tbd_1203 14 COG3189 COG3189, Uncharacterized conserved protein Function unknown 74316928 Common - TonB protein Tbd_0910 26 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 74317791 Common - tryptophan synthase subunit beta Tbd_1773 225 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 74316506 Common - putative TatD related DNase Tbd_0488 232 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 74316973 Common - Cytidylate kinase Tbd_0955 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 74317011 Nonpathogen - hypothetical protein Tbd_0993 7 None None None 74317589 Common - probable site-specific integrase/recombinase Tbd_1571 82 COG0582 XerC, Integrase DNA replication, recombination, and repair 74317769 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Tbd_1751 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 74317256 Nonpathogen - hypothetical protein Tbd_1238 1 None None None 74317363 Nonpathogen - hypothetical protein Tbd_1345 1 None None None 74317172 Common nuoM NADH dehydrogenase subunit M Tbd_1154 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 74318007 Common - ketol-acid reductoisomerase Tbd_1989 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 74318430 Common - pentitol phosphotransferase enzyme IIA component Tbd_2412 99 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 74318667 Nonpathogen - carboxysome shell protein CsoS3, carbonic anhydrase epsilon Tbd_2649 7 None None None 74318835 Nonpathogen - hypothetical protein Tbd_2817 1 None None None 74316245 Common - CyaY protein Tbd_0227 40 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 74318315 Common - ABC phosphonate permease Tbd_2297 77 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 74318012 Nonpathogen - hypothetical protein Tbd_1994 4 COG4831 COG4831, Uncharacterized conserved protein Function unknown 74318491 Common - Cobyrinic acid a,c-diamide synthase CbiA Tbd_2473 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 74316414 Common rplJ 50S ribosomal protein L10 Tbd_0396 208 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 74318776 Common - methyltransferase Tbd_2758 222 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 74317855 Common - hypothetical protein Tbd_1837 31 COG1416 COG1416, Uncharacterized conserved protein Function unknown 74316389 Nonpathogen - hypothetical protein Tbd_0371 1 None None None 74316630 Common - Protein of unknown function DUF181 Tbd_0612 47 COG1944 COG1944, Uncharacterized conserved protein Function unknown 74318611 Common - Transcriptional Regulator, Crp/Fnr family Tbd_2593 163 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 74316611 Common - hypothetical protein Tbd_0593 82 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 74317434 Common - RND efflux system outer membrane lipoprotein NodT Tbd_1416 130 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74318280 Common - hypothetical protein Tbd_2262 30 COG1873 COG1873, Uncharacterized conserved protein Function unknown 74318679 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Tbd_2661 231 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 74318498 Common - putative sulfite reductase Tbd_2480 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 74316901 Common - probable membrane protein Tbd_0883 84 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 74318604 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase Tbd_2586 179 COG0756 Dut, dUTPase Nucleotide transport and metabolism 74318428 Common - hypothetical protein Tbd_2410 63 COG3791 COG3791, Uncharacterized conserved protein Function unknown 74318559 Common - ATP-dependent protease peptidase subunit Tbd_2541 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 74318050 Common hrcA heat-inducible transcription repressor Tbd_2032 150 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 74317950 Common - hypothetical protein Tbd_1932 9 None None None 74317497 Nonpathogen - hypothetical protein Tbd_1479 1 None None None 74317872 Common - ribosomal protein S20p Tbd_1854 82 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 74316768 Common - disulfide bond chaperone, Hsp33 family Tbd_0750 96 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 74317443 Common - Protein tyrosine phosphatase Tbd_1425 123 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 74318504 Nonpathogen - hypothetical protein Tbd_2486 1 None None None 74317648 Common flgI flagellar basal body P-ring protein Tbd_1630 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 74317117 Common - uncharacterized lipoprotein Tbd_1099 38 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 74317009 Nonpathogen - hypothetical protein Tbd_0991 1 None None None 74316994 Nonpathogen - hypothetical protein Tbd_0976 4 COG3255 COG3255, Putative sterol carrier protein Lipid metabolism 74318419 Common - thioredoxin Tbd_2401 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 74318800 Common argS arginyl-tRNA synthetase Tbd_2782 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74316255 Common - Mg chelatase-related protein Tbd_0237 188 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 74317243 Nonpathogen - hypothetical protein Tbd_1225 1 None None None 74316832 Common - nicotinate-nucleotide pyrophosphorylase Tbd_0814 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 74317623 Common - putative flagellar hook-length control protein FliK Tbd_1605 43 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 74316062 Common glcF glycolate oxidase iron-sulfur subunit Tbd_0044 155 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 74318337 Common - probable RND efflux transporter Tbd_2319 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 74316534 Common - hypothetical protein Tbd_0516 189 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 74317721 Common - twin-arginine translocation protein TatB Tbd_1703 36 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 74317110 Nonpathogen - hypothetical protein Tbd_1092 1 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 74316174 Common - hypothetical protein Tbd_0156 58 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 74318293 Common - hypothetical protein Tbd_2275 32 COG3587 COG3587, Restriction endonuclease Defense mechanisms 74316662 Common - alanine dehydrogenase Tbd_0644 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 74317191 Common - alpha amylase, catalytic subdomain Tbd_1173 178 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 74318412 Common - phosphoglyceromutase Tbd_2394 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 74318287 Common - putative dienelactone hydrolase Tbd_2269 43 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 74318369 Common - ABC transpoter ATPase Tbd_2351 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 74316552 Common - ATPase component ABC-type transport system Tbd_0534 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 74316247 Common - argininosuccinate lyase Tbd_0229 235 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 74317673 Common - probable transmembrane protein Tbd_1655 37 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 74317531 Common - fructose-bisphosphate aldolase, class I Tbd_1513 40 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 74317728 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit HisH Tbd_1710 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 74317869 Common - acetylornithine aminotransferase Tbd_1851 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 74316686 Common - hypothetical protein Tbd_0668 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 74318271 Common - putative permease Tbd_2253 137 COG0628 PerM, Predicted permease General function prediction only 74317162 Common nuoC NADH dehydrogenase subunit C Tbd_1144 170 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 74316830 Common - DNA ligase Tbd_0812 37 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 74316777 Common - Protein of unknown function DUF11 Tbd_0759 58 None None None 74318357 Common - 4-hydroxythreonine-4-phosphate dehydrogenase PdxA Tbd_2339 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 74317490 Common - mercuric reductase Tbd_1472 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 74317846 Common - hypothetical protein Tbd_1828 3 None None None 74316212 Nonpathogen - hypothetical protein Tbd_0194 1 None None None 74317990 Common - transcriptional regulatory protein GntR Tbd_1972 225 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 74317966 Common - putative flavodoxin reductase Tbd_1948 66 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 74318726 Nonpathogen - hypothetical protein Tbd_2708 1 None None None 74317922 Common - peptidyl-prolyl cis-trans isomerase B Tbd_1904 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 74317263 Common - Flagellar biosynthetic protein FlhB Tbd_1245 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 74316920 Common - heavy metal efflux pump CzcA Tbd_0902 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 74317709 Nonpathogen - hypothetical protein Tbd_1691 1 None None None 74317991 Common - hypothetical protein Tbd_1973 19 COG1598 COG1598, Uncharacterized conserved protein Function unknown 74318253 Common - Histidine Kinase Tbd_2235 152 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 74317338 Common - hypothetical protein Tbd_1320 39 COG3391 COG3391, Uncharacterized conserved protein Function unknown 74317739 Common - hypothetical protein Tbd_1721 132 COG1704 LemA, Uncharacterized conserved protein Function unknown 74318579 Nonpathogen - FxsA protein Tbd_2561 2 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 74318749 Common - prolipoprotein diacylglyceryl transferase Tbd_2731 203 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 74316724 Common - conserved hypothetical signal peptide protein Tbd_0706 20 None None None 74318199 Nonpathogen - hypothetical protein Tbd_2181 1 None None None 74317448 Common - transcriptional regulatory protein, MerR family Tbd_1430 9 None None None 74316622 Common - HflC Tbd_0604 190 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 74316942 Common - 3-oxoacyl-(acyl-carrier protein) reductase Tbd_0924 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 74318150 Nonpathogen - hypothetical protein Tbd_2132 2 None None None 74318819 Common - F-type H+-transporting ATP synthase, subunit B Tbd_2801 83 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 74318298 Common - putative peptidyl-prolyl cis-trans isomerase Tbd_2280 92 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 74316772 Nonpathogen - type II secretory pathway, pseudopilin PulG Tbd_0754 3 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74318166 Common - Zn-dependent protease, modulator of DNA gyrase Tbd_2148 157 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 74316613 Common hisS histidyl-tRNA synthetase Tbd_0595 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74317702 Nonpathogen - hypothetical protein Tbd_1684 1 None None None 74316069 Common - hypothetical protein Tbd_0051 29 COG0628 PerM, Predicted permease General function prediction only 74317977 Nonpathogen - hypothetical protein Tbd_1959 1 None None None 74317694 Common clpX ATP-dependent protease ATP-binding subunit Tbd_1676 228 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 74317188 Common - hypothetical protein Tbd_1170 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 74316515 Common - putative monovalent cation/H+ antiporter subunit A Tbd_0497 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 74316633 Common - tRNA/rRNA methyltransferase Tbd_0615 54 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 74316987 Common - aspartate kinase, monofunctional class Tbd_0969 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 74317213 Common - hypothetical protein Tbd_1195 116 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 74317579 Common - hypothetical protein Tbd_1561 26 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 74316600 Common - hypothetical protein Tbd_0582 93 COG0795 COG0795, Predicted permeases General function prediction only 74318321 Common - Septum site-determining protein MinD Tbd_2303 135 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 74316406 Common - 50S ribosomal protein L25/general stress protein Ctc Tbd_0388 188 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 74317600 Common - hypothetical protein Tbd_1582 41 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 74318443 Common - probable transmembrane protein Tbd_2425 94 COG1981 COG1981, Predicted membrane protein Function unknown 74317955 Nonpathogen - hypothetical protein Tbd_1937 1 None None None 74318448 Common - putative ABC transporter ATP-binding protein Tbd_2430 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 74318690 Common - enoyl-CoA hydratase Tbd_2672 146 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 74317065 Common - cyclopropane fatty acyl phospholipid synthase Tbd_1047 130 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 74318745 Common - hypothetical protein Tbd_2727 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 74318827 Nonpathogen - hypothetical protein Tbd_2809 2 None None None 74316809 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Tbd_0791 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 74318242 Common - glutamine amidotransferase of anthranilate synthase Tbd_2224 236 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 74318373 Nonpathogen - hypothetical protein Tbd_2355 1 None None None 74318526 Common - putative cell cycle control ATPase Tbd_2508 136 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 74318582 Nonpathogen - hypothetical protein Tbd_2564 7 COG3439 COG3439, Uncharacterized conserved protein Function unknown 74317052 Common - molybdenum-pterin-binding protein, molybdate transport system regulatory protein Tbd_1034 5 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 74318275 Common - hypothetical protein Tbd_2257 13 None None None 74317887 Common - hypothetical protein Tbd_1869 11 None None None 74318343 Common - putative CBS-domain-containing membrane protein Tbd_2325 67 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 74316728 Common - hypothetical protein Tbd_0710 7 None None None 74316203 Common - putative transmembrane cytochrome C-type biogenesis transmembrane protein Tbd_0185 167 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 74316195 Common - glycine cleavage system H-protein Tbd_0177 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 74316908 Nonpathogen - hypothetical protein Tbd_0890 3 None None None 74317523 Common - 3-deoxy-D-manno-octulosonate cytidylyltransferase Tbd_1505 144 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 74317732 Common - Possible Ferric uptake regulator (FUR) family Tbd_1714 79 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 74317681 Common - ribonuclease HI Tbd_1663 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 74318203 Common - hypothetical protein Tbd_2185 48 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 74318451 Common - oligopeptidase A Tbd_2433 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 74316495 Common - ribonuclease PH Tbd_0477 183 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 74318484 Nonpathogen - hypothetical protein Tbd_2466 6 None None None 74317551 Common - host factor Hfq protein Tbd_1533 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 74317542 Common - major facilitator family transporter (permease) Tbd_1524 103 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 74317385 Common - periplasmic or secreted lipoprotein Tbd_1367 11 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 74317908 Common hisG ATP phosphoribosyltransferase catalytic subunit Tbd_1890 213 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 74316912 Nonpathogen - conserved hypothetical/unknown protein Tbd_0894 11 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 74318362 Common - hypothetical protein Tbd_2344 145 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 74316022 Nonpathogen - hypothetical protein Tbd_0004 1 None None None 74317403 Common - Hydrogenase maturation protein HypF Tbd_1385 114 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 74317752 Common gltX glutamyl-tRNA synthetase Tbd_1734 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 74318731 Common - adenosylcobinamide kinase / adenosylcobinamide-phosphate guanylyltransferase Tbd_2713 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 74318210 Common - NusB antitermination factor Tbd_2192 176 COG0781 NusB, Transcription termination factor Transcription 74318565 Nonpathogen - hypothetical protein Tbd_2547 2 None None None 74317238 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase Tbd_1220 149 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 74317815 Common - CAAX amino terminal protease family protein Tbd_1797 19 None None None 74316345 Nonpathogen - hypothetical protein Tbd_0327 1 None None None 74317454 Common - hypothetical protein Tbd_1436 7 None None None 74318320 Common - septum formation inhibitor MinC Tbd_2302 98 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 74316355 Common - putative SCO1/SenC family protein, Tbd_0337 105 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 74316656 Common - hypothetical protein Tbd_0638 29 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 74316133 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alanyl-D-alanyl ligase Tbd_0115 212 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 74316056 Common - hypothetical protein Tbd_0038 7 COG1158 Rho, Transcription termination factor Transcription 74317097 Common - hypothetical protein Tbd_1079 7 None None None 74318264 Common - putative Ku-like DNA-end-binding protein Tbd_2246 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 74318302 Nonpathogen - hypothetical protein Tbd_2284 2 None None None 74318392 Common - 16S rRNA processing protein RimM Tbd_2374 184 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 74317121 Common - putative hydrolase Tbd_1103 71 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 74318747 Common - probable partition-related protein Tbd_2729 150 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 74317019 Common - thioredoxin reductase Tbd_1001 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 74318101 Common - pyridoxal phosphate biosynthetic protein PdxJ Tbd_2083 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 74318520 Common - hypothetical protein Tbd_2502 10 None None None 74316026 Common - rhodanese-like protein Tbd_0008 38 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 74318239 Common - hypothetical protein Tbd_2221 76 COG0433 COG0433, Predicted ATPase General function prediction only 74317948 Common - putative oxidase Tbd_1930 11 None None None 74318380 Common - SLT domain protein Tbd_2362 164 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 74318064 Common - hypothetical protein Tbd_2046 51 COG3531 COG3531, Predicted protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 74317665 Nonpathogen - heterodisulfide reductase, subunit A Tbd_1647 47 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 74317895 Common - ABC transporter ATPase Tbd_1877 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 74316404 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Tbd_0386 190 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 74318139 Common - 6-phosphogluconolactonase Tbd_2121 111 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 74318614 Common - long chain fatty acid transport protein Tbd_2596 88 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 74316799 Nonpathogen - hypothetical protein Tbd_0781 1 None None None 74317144 Common - glutaredoxin 3 Tbd_1126 114 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 74316223 Common - type IV pilus assembly protein PilP Tbd_0205 39 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 74316276 Common - glutamyl-tRNA(Gln) amidotransferase A subunit Tbd_0258 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 74317710 Common - putative ATPase Tbd_1692 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 74316648 Common - phosphoenolpyruvate carboxylase Tbd_0630 118 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 74316752 Common - putative short chain dehydrogenase Tbd_0734 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 74316852 Common - putative signal peptide protein Tbd_0834 74 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 74317660 Common - putative periplasmic protein Tbd_1642 40 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 74317169 Common nuoJ NADH dehydrogenase I chain J Tbd_1151 83 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 74316316 Common - amidotransferase Tbd_0298 129 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 74317610 Common - flagellar hook-associated protein 2 Tbd_1592 110 COG1345 FliD, Flagellar capping protein Cell motility and secretion 74316995 Common - hypothetical protein Tbd_0977 9 None None None 74318717 Common - nucleoside-diphosphate-sugar epimerase Tbd_2699 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74318686 Common - phosphoribosylaminoimidazole-succinocarboxamide (SAICAR) synthetase Tbd_2668 205 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 74318527 Common - alanine-glyoxylate transaminase Tbd_2509 159 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 74317934 Common truA tRNA pseudouridine synthase A Tbd_1916 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 74318740 Nonpathogen - hypothetical protein Tbd_2722 3 None None None 74317506 Nonpathogen - hypothetical protein Tbd_1488 4 None None None 74316285 Common - D-alanine transminase Tbd_0267 183 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 74316466 Common - outer membrane protein (porin) Tbd_0448 40 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 74316797 Common - pseudouridine synthase, Rsu Tbd_0779 201 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 74318598 Common - Holliday junction resolvase-like protein Tbd_2580 191 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 74318181 Common - putative ubiquinone biosynthesis monooxygenase Coq7 Tbd_2163 45 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 74316845 Common - DNA polymerase III, epsilon subunit Tbd_0827 231 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 74316581 Common - probable sulfur oxidation signal protein, twin-arginine translocation pathway Tbd_0563 132 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 74316459 Common - probable transmembrane protein Tbd_0441 72 COG2928 COG2928, Uncharacterized conserved protein Function unknown 74316568 Common - ATPase, Type II secretory pathway component Tbd_0550 64 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 74317294 Common - putative NAD/FAD-dependent oxidoreductase Tbd_1276 14 COG3380 COG3380, Predicted NAD/FAD-dependent oxidoreductase General function prediction only 74317687 Common - oligopeptide ABC transporter permease protein Tbd_1669 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 74317250 Common - Putative Serine protein kinase, PrkA Tbd_1232 69 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 74317989 Nonpathogen - hypothetical protein Tbd_1971 2 None None None 74317650 Common - flagellar basal body rod protein FlgG Tbd_1632 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 74317017 Common - bacterioferritin comigratory protein Tbd_0999 210 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 74318304 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Tbd_2286 140 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 74318756 Common - putative metallo-beta-lactamase family protein Tbd_2738 201 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 74318660 Nonpathogen - hypothetical protein Tbd_2642 7 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 74317111 Nonpathogen - hypothetical protein Tbd_1093 1 None None None 74318338 Common - Secretion protein HlyD Tbd_2320 140 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 74316690 Common - Possible Plasmid maintenance system antidote protein Tbd_0672 61 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 74316147 Common - cytochrome c-type protein Tbd_0129 62 COG2863 COG2863, Cytochrome c553 Energy production and conversion 74317843 Common - putative DNA helicase Tbd_1825 29 COG3598 RepA, RecA-family ATPase DNA replication, recombination, and repair 74318014 Common - hypothetical protein Tbd_1996 4 None None None 74316447 Common rpsD 30S ribosomal protein S4 Tbd_0429 221 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 74316499 Common folE GTP cyclohydrolase I Tbd_0481 175 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 74317466 Nonpathogen - hypothetical protein Tbd_1448 1 None None None 74318089 Nonpathogen - hypothetical protein Tbd_2071 2 None None None 74318132 Nonpathogen - hypothetical protein Tbd_2114 1 None None None 74316092 Common - Possible Transcriptional Regulator, AsnC family Tbd_0074 51 COG1522 Lrp, Transcriptional regulators Transcription 74318077 Common - 4-alpha-glucanotransferase Tbd_2059 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 74318425 Common - RNA methyltransferase CspR Tbd_2407 157 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 74317182 Common - Cysteine desulfurase IscS Tbd_1164 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 74318036 Common - Electron transport complex, RnfABCDGE type, D subunit Tbd_2018 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 74317564 Common - hypothetical protein Tbd_1546 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 74316549 Common - Possible PTS IIA-like nitrogen-regulatory protein PtsN Tbd_0531 133 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 74316230 Common - probable sodium/solute symporter Tbd_0212 164 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 74318289 Common - Response regulator receiver domain protein (CheY) Tbd_2271 81 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 74317032 Common - Transcriptional Regulator, MerR family Tbd_1014 86 COG0789 SoxR, Predicted transcriptional regulators Transcription 74318230 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_2212 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 74318706 Common - TonB-dependent receptor protein Tbd_2688 53 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 74316123 Common - Cytidyltransferase Tbd_0105 120 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 74318692 Common - hypothetical protein Tbd_2674 93 COG2947 COG2947, Uncharacterized conserved protein Function unknown 74317226 Nonpathogen - hypothetical protein Tbd_1208 1 None None None 74317190 Common - alpha amylase, catalytic subdomain Tbd_1172 170 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 74318330 Common - small heat shock protein Tbd_2312 151 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 74318729 Common - alpha-ribazole-5`-phosphate phosphatase CobC, putative Tbd_2711 118 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 74316576 Common - putative nitric oxide reductase activation protein NorQ, Tbd_0558 81 COG0714 COG0714, MoxR-like ATPases General function prediction only 74316081 Common - hypothetical protein Tbd_0063 6 None None None 74316364 Nonpathogen - transposase, TnsA-related protein Tbd_0346 4 None None None 74316020 Common - DNA polymerase III, beta chain Tbd_0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 74318236 Common - hypothetical protein Tbd_2218 52 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 74316226 Nonpathogen - hypothetical protein Tbd_0208 7 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 74318538 Common - K+-dependent Na+/Ca+ exchanger related-protein Tbd_2520 112 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 74317525 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_1507 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 74318456 Common maf Maf-like protein Tbd_2438 192 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 74318844 Common - ribonuclease P protein component Tbd_2826 53 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 74317547 Common - Intracellular septation protein A Tbd_1529 93 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 74316046 Common - ATPase Tbd_0028 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 74318031 Nonpathogen - hypothetical protein Tbd_2013 2 None None None 74318000 Common - hypothetical protein Tbd_1982 108 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 74316088 Common - nitrite reductase (NO-forming) Tbd_0070 20 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 74316262 Common - probable outer membrane protein Tbd_0244 168 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 74317333 Common - hypothetical protein Tbd_1315 8 None None None 74317617 Common fliE flagellar hook-basal body protein FliE Tbd_1599 82 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 74316258 Common - Nitrogen regulatory protein P-II (GlnB, GlnK) Tbd_0240 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 74317975 Common - hypothetical protein Tbd_1957 8 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 74318720 Common - hypothetical protein Tbd_2702 87 COG1565 COG1565, Uncharacterized conserved protein Function unknown 74316393 Common - Cell division ATP-binding protein FtsE, ABC transporter ATP-binding protein Tbd_0375 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 74316386 Common - pyruvate,orthophosphate dikinase Tbd_0368 99 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 74316103 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) and Response Regulator Receiver modulation Tbd_0085 225 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74317647 Common - mannosyl-glycoprotein endo-beta-N-acetylglucosamidase Tbd_1629 73 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 74317914 Common - putative signal peptide protein Tbd_1896 91 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 74316162 Nonpathogen - hypothetical protein Tbd_0144 2 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74318153 Common - hypothetical protein Tbd_2135 29 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 74316718 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Tbd_0700 194 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 74317679 Common - hypothetical protein Tbd_1661 10 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 74316596 Nonpathogen - hypothetical protein Tbd_0578 1 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 74317388 Common - small heat shock protein Tbd_1370 166 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 74316492 Common - hypothetical protein Tbd_0474 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 74317020 Common - cell division transmembrane protein ftsK Tbd_1002 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 74317157 Common - phosphate transport system permease protein 1 Tbd_1139 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 74316642 Common - NAD-dependent DNA ligase Tbd_0624 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 74316183 Common - hypothetical protein Tbd_0165 7 None None None 74318486 Common - pyruvate:ferredoxin (flavodoxin) oxidoreductase Tbd_2468 108 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 74317394 Common - heterodisulfide reductase Tbd_1376 93 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 74316307 Common - glycosyl transferase group 1 Tbd_0289 66 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74318576 Nonpathogen - hypothetical protein Tbd_2558 2 None None None 74317105 Common - Phosphohistidine Phosphatase, SixA Tbd_1087 33 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 74316154 Common - Two component Transcriptional regulator, Winged helix family Tbd_0136 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74318295 Common - hypothetical protein Tbd_2277 3 None None None 74317488 Nonpathogen - hypothetical protein Tbd_1470 1 None None None 74318812 Common - glucoamine-1-phosphate N-acetyltransferase, UDP-N-acetylglucosamine pyrophosphorylase Tbd_2794 228 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 74316182 Nonpathogen - hypothetical protein Tbd_0164 1 None None None 74316700 Common - hypothetical protein Tbd_0682 32 None None None 74316854 Common - Protein-L-isoaspartate(D-aspartate) O-methyltransferase Tbd_0836 156 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 74317130 Common - hypothetical protein Tbd_1112 148 COG1741 COG1741, Pirin-related protein General function prediction only 74316860 Common - aminotransferase AlaT Tbd_0842 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 74316169 Common - ABC transporter, ATP-binding protein Tbd_0151 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 74317884 Common - putative D-amino acid oxidase Tbd_1866 134 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 74316561 Nonpathogen - hypothetical protein Tbd_0543 1 None None None 74316955 Common - hypothetical protein Tbd_0937 47 COG3421 COG3421, Uncharacterized protein conserved in bacteria Function unknown 74317029 Common - phenylalanyl-tRNA synthetase, alpha subunit Tbd_1011 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 74316114 Common - phospholipase Tbd_0096 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 74317398 Common - peptidase M52, hydrogen uptake protein Tbd_1380 62 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 74317278 Common - hypothetical protein Tbd_1260 31 COG1152 CdhA, CO dehydrogenase/acetyl-CoA synthase alpha subunit Energy production and conversion 74316915 Nonpathogen - hypothetical protein Tbd_0897 2 None None None 74317366 Nonpathogen - hypothetical protein Tbd_1348 1 None None None 74317573 Common - acetyl-CoA carboxylase Tbd_1555 237 COG0439 AccC, Biotin carboxylase Lipid metabolism 74316570 Common - hypothetical protein Tbd_0552 7 None None None 74316789 Nonpathogen - hypothetical protein Tbd_0771 1 None None None 74316775 Nonpathogen - hypothetical protein Tbd_0757 6 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74318018 Nonpathogen - hypothetical protein Tbd_2000 1 None None None 74318761 Common - hypothetical protein Tbd_2743 6 None None None 74318824 Common - chromosome partitioning protein ParA Tbd_2806 226 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 74318530 Nonpathogen - hypothetical protein Tbd_2512 1 None None None 74317324 Common - ATP-dependent DNA helicase Tbd_1306 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 74316317 Nonpathogen - hypothetical protein Tbd_0299 4 None None None 74317616 Common - CheW protein Tbd_1598 133 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 74317145 Common - Carbamoyl-phosphate synthase, small subunit Tbd_1127 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 74316682 Common - hypothetical protein Tbd_0664 16 None None None 74317827 Common - hypothetical protein Tbd_1809 4 None None None 74316050 Common - hypothetical protein Tbd_0032 49 None None None 74317315 Common - possible transmembrane protein Tbd_1297 8 None None None 74317823 Nonpathogen - hypothetical protein Tbd_1805 1 None None None 74317075 Common - hypothetical protein Tbd_1057 40 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 74316968 Common - D-isomer specific 2-hydroxyacid dehydrogenase Tbd_0950 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 74317836 Nonpathogen - hypothetical protein Tbd_1818 1 None None None 74316450 Common - hypothetical protein Tbd_0432 74 COG1912 COG1912, Uncharacterized conserved protein Function unknown 74316521 Common - putative glutamate-ammonia-ligase adenylyltransferase Tbd_0503 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 74318114 Common - L-aspartate oxidase Tbd_2096 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 74316709 Common - Transcriptional regulators, TraR/DksA family Tbd_0691 156 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 74317067 Common - hypothetical protein Tbd_1049 65 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 74318188 Common - putative pyruvate radical-activating enzyme Tbd_2170 104 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 74318282 Common - hypothetical protein Tbd_2264 8 None None None 74316477 Common - tyrosyl-tRNA synthetase Tbd_0459 238 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74317538 Common - 4Fe-4S ferredoxin protein Tbd_1520 135 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 74317984 Common - hypothetical protein Tbd_1966 53 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 74318163 Common - hypothetical protein Tbd_2145 3 None None None 74316039 Common - trk system potassium uptake membrane protein TrkH Tbd_0021 119 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 74316764 Common - hypothetical protein Tbd_0746 3 None None None 74317043 Common - molybdopterin binding domain Tbd_1025 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 74317593 Nonpathogen - hypothetical protein Tbd_1575 1 None None None 74317345 Common - heavy metal efflux pump CzcA Tbd_1327 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 74317150 Common - cell division protein FtsJ Tbd_1132 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 74318672 Nonpathogen - hypothetical protein Tbd_2654 3 None None None 74318402 Common - o-sialoglycoprotein endopeptidase Tbd_2384 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 74316817 Common - ribonuclease H Tbd_0799 202 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 74316741 Common - cytochrome c, class I Tbd_0723 64 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 74317634 Common - CheD, stimulates methylation of MCP proteins Tbd_1616 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 74318060 Common - arginyl-tRNA-protein transferase Tbd_2042 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 74316704 Common - acyl-CoA thioesterase I precursor Tbd_0686 96 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 74317864 Common - nucleotide-binding protein Tbd_1846 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 74317764 Common - heavy metal efflux pump CzcA Tbd_1746 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 74317835 Nonpathogen - hypothetical protein Tbd_1817 1 None None None 74317788 Common - putative flavodoxin oxidoreductase Tbd_1770 96 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 74318752 Nonpathogen - hypothetical protein Tbd_2734 1 None None None 74316940 Common - MgtC family protein Tbd_0922 57 COG3174 COG3174, Predicted membrane protein Function unknown 74317005 Common - Multi-sensor Hybrid Histidine Kinase Tbd_0987 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74318606 Common - DNA repair protein RadC Tbd_2588 177 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 74316235 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Tbd_0217 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 74318551 Common - Transcriptional regulators, TraR/DksA family Tbd_2533 140 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 74318044 Common - cytochrome c, class IC Tbd_2026 49 COG2863 COG2863, Cytochrome c553 Energy production and conversion 74317618 Common fliF flagellar MS-ring protein Tbd_1600 127 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 74316599 Common - hypothetical protein Tbd_0581 75 COG0795 COG0795, Predicted permeases General function prediction only 74316193 Nonpathogen - hypothetical protein Tbd_0175 3 None None None 74317025 Common - threonyl-tRNA synthetase, class IIa Tbd_1007 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74317027 Common - ribosomal protein L35 Tbd_1009 167 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 74317775 Common - tRNA 2-selenouridine synthase Tbd_1757 65 COG2603 COG2603, Predicted ATPase General function prediction only 74316540 Common - HesA/MoeB/ThiF family protein Tbd_0522 174 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 74317633 Common - chemotaxis-specific methylesterase Tbd_1615 214 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 74316019 Common - chromosomal replication initiator protein, DnaA Tbd_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 74317838 Common - TrwC protein Tbd_1820 98 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 74316055 Common rho transcription termination factor Rho Tbd_0037 211 COG1158 Rho, Transcription termination factor Transcription 74317295 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_1277 176 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 74318546 Common - tyrosine recombinase XerC Tbd_2528 226 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 74317016 Nonpathogen - hypothetical protein Tbd_0998 1 None None None 74317802 Common - probable glycosyltransferase Tbd_1784 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74318055 Nonpathogen - hypothetical protein Tbd_2037 1 None None None 74318370 Nonpathogen - hypothetical protein Tbd_2352 1 None None None 74317342 Common - Copper-resistance protein CopA Tbd_1324 130 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 74317079 Common - Putative diguanylate phosphodiesterase (EAL domain) with GAF sensor Tbd_1061 164 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 74318223 Common - outer membrane protein, porin-associated lipoprotein Tbd_2205 138 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 74317587 Common - aspartate aminotransferase Tbd_1569 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 74318809 Common - Two component Transcriptional regulator, Winged helix family Tbd_2791 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74318075 Common - glycogen/starch synthase, ADP-glucose type Tbd_2057 148 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 74316457 Common - hypothetical protein Tbd_0439 117 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 74318654 Common cbbO2 rubisco activation protein cbbO Tbd_2636 45 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 74317322 Common - cyclic beta 1-2 glucan synthetase Tbd_1304 45 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 74318128 Common - dinucleoside polyphosphate hydrolase Tbd_2110 112 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 74317770 Common - IMP dehydrogenase Tbd_1752 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 74318409 Nonpathogen - hypothetical protein Tbd_2391 3 None None None 74317387 Common - sulfite reductase, dissimilatory-type alpha subunit Tbd_1369 34 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 74316787 Common - hypothetical protein Tbd_0769 57 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 74317428 Common - gamma-glutamyltranspeptidase Tbd_1410 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 74317128 Common - conserved hypothetical protein containing TPR repeat Tbd_1110 15 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 74318676 Common - DsrC -like protein Tbd_2658 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 74318088 Common - Possible Transcriptional Regulator Tbd_2070 7 COG3311 AlpA, Predicted transcriptional regulator Transcription 74318161 Common mogA molybdenum cofactor biosynthesis protein Tbd_2143 187 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 74317375 Nonpathogen - hypothetical protein Tbd_1357 5 COG3909 COG3909, Cytochrome c556 Energy production and conversion 74317228 Common - hypothetical protein Tbd_1210 21 COG4333 COG4333, Uncharacterized protein conserved in bacteria Function unknown 74317379 Common - RND efflux membrane protein Tbd_1361 97 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 74316433 Common rplN 50S ribosomal protein L14 Tbd_0415 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 74317790 Common - hypothetical protein Tbd_1772 169 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 74318483 Common - hypothetical protein Tbd_2465 24 COG3461 COG3461, Uncharacterized conserved protein Function unknown 74317985 Common - hypothetical protein Tbd_1967 53 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 74316163 Common - hypothetical protein with SEL1 repeat Tbd_0145 97 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 74317452 Common - type II secretion system protein E Tbd_1434 216 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 74317591 Nonpathogen - Possible Transcriptional Regulator Tbd_1573 1 COG3311 AlpA, Predicted transcriptional regulator Transcription 74317976 Nonpathogen - hypothetical protein Tbd_1958 1 None None None 74318587 Nonpathogen - hypothetical protein Tbd_2569 6 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 74317296 Common - hypothetical protein Tbd_1278 87 COG1262 COG1262, Uncharacterized conserved protein Function unknown 74318342 Common - hypothetical protein Tbd_2324 86 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 74318553 Common - Protein of unknown function DUF37 Tbd_2535 182 COG0759 COG0759, Uncharacterized conserved protein Function unknown 74317850 Common - cytochrome B subunit of cytochrome bc1 Tbd_1832 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 74316291 Nonpathogen - hypothetical protein Tbd_0273 1 None None None 74317365 Common - transcriptional regulator Tbd_1347 3 COG2944 COG2944, Predicted transcriptional regulator Transcription 74316443 Common secY preprotein translocase subunit SecY Tbd_0425 224 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 74317501 Common - peptidase S24, LexA repressor Tbd_1483 172 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 74318665 Nonpathogen - Carboxysome protein B Tbd_2647 7 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 74317813 Common - polysaccharide export outer membrane protein Tbd_1795 125 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 74318355 Common - organic solvent tolerance transmembrane protein Tbd_2337 120 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 74317368 Nonpathogen - hypothetical protein Tbd_1350 1 None None None 74317652 Common flgE flagellar hook protein FlgE Tbd_1634 131 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 74317582 Common - ribonuclease E and G Tbd_1564 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 74316598 Common - leucyl aminopeptidase Tbd_0580 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 74317273 Common - Possible Transcriptional Regulator, TetR family Tbd_1255 87 COG1309 AcrR, Transcriptional regulator Transcription 74316713 Common - tRNA pseudouridine synthase B Tbd_0695 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 74317281 Common - hypothetical protein Tbd_1263 81 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 74316089 Common - Elongator protein 3/MiaB/NifB Tbd_0071 156 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 74316773 Nonpathogen - general secretion pathway protein H Tbd_0755 5 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 74316813 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase, LpxD Tbd_0795 147 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 74318478 Common - probable Sua5/YciO/YrdC family protein Tbd_2460 185 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 74316327 Common - glycosyltransferase Tbd_0309 166 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 74316148 Common - hypothetical protein Tbd_0130 10 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 74317641 Common - CheW protein Tbd_1623 123 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 74316102 Common - Histidine Kinase Tbd_0084 200 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 74317357 Common - putative mercuric transport protein Tbd_1339 23 None None None 74316917 Common - peptidase M, neutral zinc metallopeptidase, zinc-binding site Tbd_0899 160 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 74316705 Common - hypothetical protein Tbd_0687 86 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 74318840 Common - Possible Transcriptional Regulator Tbd_2822 36 COG3311 AlpA, Predicted transcriptional regulator Transcription 74318460 Common proA gamma-glutamyl phosphate reductase Tbd_2442 189 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 74316980 Common - RfaE bifunctional protein, domain I Tbd_0962 109 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 74316467 Nonpathogen - hypothetical protein Tbd_0449 2 None None None 74316310 Common - asparagine synthase, glutamine-hydrolyzing Tbd_0292 157 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 74317390 Nonpathogen - hypothetical protein Tbd_1372 4 None None None 74317809 Nonpathogen - hypothetical protein Tbd_1791 7 None None None 74316378 Common - hypothetical protein Tbd_0360 16 None None None 74316111 Common - adenosylmethionine--8-amino-7-oxononanoate aminotransferase Tbd_0093 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 74318590 Common - UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase Tbd_2572 207 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 74317031 Common ihfA integration host factor subunit alpha Tbd_1013 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 74316971 Common - 3-phosphoshikimate 1-carboxyvinyltransferase/prephenate dehydrogenase Tbd_0953 159 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 74317184 Common - Iron-sulphur cluster assembly protein IscA Tbd_1166 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 74318068 Common - poly(A) polymerase, PcnB Tbd_2050 210 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 74316077 Common - predicted kinase Tbd_0059 58 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 74317611 Common - flagellar protein FliS Tbd_1593 83 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 74318288 Common - hypothetical protein Tbd_2270 25 COG4588 AcfC, Accessory colonization factor AcfC, contains ABC-type periplasmic domain General function prediction only 74317082 Common - hypothetical protein Tbd_1064 86 COG3384 COG3384, Uncharacterized conserved protein Function unknown 74318033 Common - Electron transport complex, RnfABCDGE type, A subunit Tbd_2015 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 74317196 Common - flagellar biosynthetic protein FlhF Tbd_1178 83 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 74316896 Common - hypothetical protein Tbd_0878 79 COG1469 COG1469, Uncharacterized conserved protein Function unknown 74316688 Common - Two Component Transcriptional Regulator, LuxR family Tbd_0670 150 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 74316793 Common purT phosphoribosylglycinamide formyltransferase 2 Tbd_0775 207 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 74318441 Common - Prevent-host-death protein Tbd_2423 20 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 74317766 Common - putative outer membrane protein Tbd_1748 32 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74316857 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Tbd_0839 36 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 74317730 Common - histidinol-phosphate aminotransferase Tbd_1712 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 74318514 Nonpathogen - hypothetical protein Tbd_2496 1 None None None 74316674 Common - leucyl aminopeptidase Tbd_0656 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 74318426 Common - glutamate--cysteine ligase GshA Tbd_2408 27 None None None 74317430 Common - hypothetical protein Tbd_1412 193 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 74316227 Common - hypothetical protein Tbd_0209 12 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 74316401 Common - formamidopyrimidine-DNA glycolase Tbd_0383 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 74317553 Common - hypothetical protein Tbd_1535 54 COG0398 COG0398, Uncharacterized conserved protein Function unknown 74317561 Common - thymidylate kinase Tbd_1543 229 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 74318385 Common - dephospho-CoA kinase Tbd_2367 204 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 74318262 Common - hypothetical protein Tbd_2244 6 None None None 74316363 Common - sigma-70 factor Tbd_0345 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 74318699 Common - Predicted transcriptional regulator Tbd_2681 67 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 74316963 Common - putative 2-phosphoglycolate phosphatase Tbd_0945 201 COG0546 Gph, Predicted phosphatases General function prediction only 74317717 Common - probable oxidoreductase Tbd_1699 211 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 74318738 Common - iron complex outermembrane recepter protein Tbd_2720 124 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 74317930 Common - acetyl-CoA carboxylase carboxyl transferase, beta subunit Tbd_1912 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 74318366 Common glyQ glycyl-tRNA synthetase subunit alpha Tbd_2348 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 74316867 Common - hypothetical protein Tbd_0849 10 None None None 74317708 Nonpathogen - hypothetical protein Tbd_1690 1 None None None 74316843 Common - nitric oxide reductase activase protein Tbd_0825 42 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 74318832 Common - Putative diguanylate cyclase (GGDEF domain) with PAS/PAC sensor domain Tbd_2814 185 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 74318283 Nonpathogen - hypothetical protein Tbd_2265 1 None None None 74316571 Common alaS alanyl-tRNA synthetase Tbd_0553 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74318118 Common - alanine racemase Tbd_2100 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 74316249 Common - Response regulator receiver domain protein (CheY) Tbd_0231 143 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 74318387 Common - type IV pilus assembly protein PilC Tbd_2369 146 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 74316207 Common - delta-aminolevulinic acid dehydratase Tbd_0189 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 74318038 Common - SoxR-reducing system protein RsxE Tbd_2020 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 74317669 Common - hypothetical protein Tbd_1651 30 COG0622 COG0622, Predicted phosphoesterase General function prediction only 74316934 Common - hypothetical protein Tbd_0916 84 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 74318577 Common - thiol:disulfide interchange protein DsbD Tbd_2559 101 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 74316839 Nonpathogen - hypothetical protein Tbd_0821 1 None None None 74316044 Common - hypothetical protein Tbd_0026 5 None None None 74316139 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase Tbd_0121 206 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 74318839 Nonpathogen - hypothetical protein Tbd_2821 1 None None None 74318753 Common - hypothetical protein Tbd_2735 160 COG0730 COG0730, Predicted permeases General function prediction only 74316626 Common - exoribonuclease II Tbd_0608 199 COG0557 VacB, Exoribonuclease R Transcription 74316493 Common - Serine/Threonine protein kinase Tbd_0475 139 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 74316269 Common - hypothetical protein Tbd_0251 13 None None None 74317549 Common - putative stress-induced morphogen BolA Tbd_1531 31 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 74317134 Common - transcriptional regulatory protein, LysR family Tbd_1116 182 COG0583 LysR, Transcriptional regulator Transcription 74316470 Common - probable transmembrane protein Tbd_0452 80 COG1434 COG1434, Uncharacterized conserved protein Function unknown 74317522 Common - adenylate kinase Tbd_1504 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 74317174 Common - hypothetical protein Tbd_1156 11 None None None 74318172 Common - hypothetical protein Tbd_2154 12 COG5626 COG5626, Uncharacterized small conserved protein Function unknown 74316237 Common - (S)-2-hydroxy-acid oxidase Tbd_0219 178 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 74318182 Common - transporter, periplasmic component Tbd_2164 86 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 74317937 Common - aspartate-semialdehyde dehydrogenase Tbd_1919 198 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 74317949 Common - putative asparaginase Tbd_1931 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 74317485 Nonpathogen - hypothetical protein Tbd_1467 1 None None None 74316978 Common - orotidine 5'-phosphate decarboxylase Tbd_0960 150 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 74316527 Common - RNA-binding S4 protein Tbd_0509 105 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 74318291 Common - nitrate transport permease Tbd_2273 188 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 74317651 Common flgF flagellar basal body rod protein FlgF Tbd_1633 125 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 74317675 Common - hypothetical protein Tbd_1657 46 COG4198 COG4198, Uncharacterized conserved protein Function unknown 74316243 Nonpathogen - histone protein Tbd_0225 1 None None None 74317680 Common - DNA polymerase III, epsilon subunit Tbd_1662 186 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 74317223 Common - pyrimidine dimer DNA glycosylase Tbd_1205 7 None None None 74318063 Nonpathogen - Cytochrome oxidase maturation protein cbb3-type Tbd_2045 2 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 74318765 Common - hypothetical protein Tbd_2747 16 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 74317781 Common - hypothetical protein Tbd_1763 29 COG4255 COG4255, Uncharacterized protein conserved in bacteria Function unknown 74317574 Common - pyruvate carboxylase subunit B Tbd_1556 199 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 74316646 Common - hypothetical protein Tbd_0628 9 None None None 74318309 Common - ABC phosphonate transport system ATPase Tbd_2291 249 COG4778 PhnL, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 74317994 Common - ribonucleotide-diphosphate reductase subunit alpha Tbd_1976 223 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 74318535 Common - 5,10-methylenetetrahydrofolate reductase (FADH) Tbd_2517 144 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 74316993 Common - FKBP-type peptidyl-prolyl cis-trans isomerase (Rotamase) protein Tbd_0975 104 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 74316043 Common - phosphate uptake regulator PhoU Tbd_0025 197 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 74318022 Common - Possible Transcriptional Regulator Tbd_2004 7 COG3311 AlpA, Predicted transcriptional regulator Transcription 74316028 Common - DNA topoisomerase I Tbd_0010 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 74318327 Common - nitrite and sulfite reductase iron-sulfur/siroheme-binding site Tbd_2309 219 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 74317874 Common - riboflavin kinase Tbd_1856 211 COG0196 RibF, FAD synthase Coenzyme metabolism 74318684 Common - phosphoribosylglycinamide formyltransferase Tbd_2666 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 74317602 Common - hypothetical protein Tbd_1584 28 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 74317465 Common - Possible Sigma 54 modulation protein/ribosomal protein S30EA Tbd_1447 25 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 74318631 Common - hypothetical protein Tbd_2613 56 COG0730 COG0730, Predicted permeases General function prediction only 74318715 Common - type I secretion outer membrane protein, TolC Tbd_2697 142 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74316315 Common - hypothetical protein Tbd_0297 26 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 74318058 Common - thymidylate synthase Tbd_2040 137 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 74318213 Common - CinA protein Tbd_2195 191 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 74318671 Common - hypothetical protein Tbd_2653 40 COG3002 COG3002, Uncharacterized protein conserved in bacteria Function unknown 74316684 Common - chorismate synthase Tbd_0666 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 74316699 Nonpathogen - hypothetical protein Tbd_0681 2 None None None 74317200 Common - succinate dehydrogenase cytochrome b-556 subunit Tbd_1182 70 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 74318353 Common - putative nucleotidyl transferase Tbd_2335 179 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 74317664 Common - heterodisulfide reductase subunit C Tbd_1646 36 COG1150 HdrC, Heterodisulfide reductase, subunit C Energy production and conversion 74317594 Common - putative hydrolase Tbd_1576 209 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 74316831 Common - putative acetyltransferase Tbd_0813 45 COG0456 RimI, Acetyltransferases General function prediction only 74317209 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) and Response Regulator Receiver modulation Tbd_1191 196 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74318436 Common - hypothetical protein Tbd_2418 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 74317069 Common - phospholipase D/Transphosphatidylase Tbd_1051 153 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 74318605 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase Tbd_2587 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 74317103 Common - polyphosphate kinase Tbd_1085 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 74317992 Common - hypothetical protein Tbd_1974 8 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 74317539 Common - hypothetical protein Tbd_1521 56 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 74316806 Common - ribosome recycling factor Tbd_0788 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 74317818 Nonpathogen - hypothetical protein Tbd_1800 2 None None None 74316614 Common - hypothetical protein Tbd_0596 60 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 74317325 Common - hypothetical protein Tbd_1307 8 None None None 74318704 Common - acetylglutamate kinase Tbd_2686 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 74317414 Common - hypothetical protein Tbd_1396 3 None None None 74316652 Common - hypothetical protein Tbd_0634 28 None None None 74318481 Common - GAF Sensor Signal Transduction Histidine Kinase Tbd_2463 145 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 74318361 Common - lactoylglutathione lyase Tbd_2343 123 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 74316730 Common - MotA/TolQ/ExbB proton channel family protein Tbd_0712 149 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 74316815 Common - UDP-N-acetylglucosamine acyltransferase Tbd_0797 148 COG1043 LpxA, Acyl- acyl carrier protein 74317409 Common - Nitrous oxidase accessory protein Tbd_1391 50 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 74317314 Common - hypothetical protein Tbd_1296 7 None None None 74316583 Common - hypothetical protein Tbd_0565 35 None None None 74318245 Common - Possible Transcriptional Regulator, Fis family Tbd_2227 175 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 74316063 Common - probable ring-cleaving dioxygenase Tbd_0045 50 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 74318444 Common - hypothetical protein Tbd_2426 9 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 74318475 Common - Transcriptional Regulator, Fis family Tbd_2457 100 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 74317529 Common - Exonuclease VII, large subunit Tbd_1511 204 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 74317437 Common - Possible Transcriptional Regulator, TetR family Tbd_1419 89 COG1309 AcrR, Transcriptional regulator Transcription 74317148 Common - hypothetical protein Tbd_1130 19 None None None 74316201 Common - 3-dehydroquinate dehydratase Tbd_0183 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 74316923 Nonpathogen - hypothetical protein Tbd_0905 4 COG3439 COG3439, Uncharacterized conserved protein Function unknown 74317958 Common - hypothetical protein Tbd_1940 87 COG1432 COG1432, Uncharacterized conserved protein Function unknown 74317057 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_1039 219 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 74318258 Nonpathogen - hypothetical protein Tbd_2240 1 COG4575 ElaB, Uncharacterized conserved protein Function unknown 74316894 Common - hypothetical protein Tbd_0876 120 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 74316948 Common - hypothetical protein Tbd_0930 16 None None None 74316644 Common - hypothetical protein Tbd_0626 220 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 74316778 Common - hypothetical protein Tbd_0760 11 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 74317605 Common - Possible Sensor with PAS/PAC domain Tbd_1587 158 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 74316631 Common - conserved hypothetical protein with TPR repeat Tbd_0613 19 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 74318196 Common - Possible Transcriptional Regulator, TetR family Tbd_2178 85 COG1309 AcrR, Transcriptional regulator Transcription 74316445 Common rpsM 30S ribosomal protein S13 Tbd_0427 244 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 74318137 Common aspA aspartate ammonia-lyase Tbd_2119 236 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 74316343 Common - cytochrome c oxidase subunit II Tbd_0325 158 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 74318432 Common - Phosphoenolpyruvate-protein phosphotransferase Tbd_2414 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 74316826 Common - Nitrogen regulatory protein P-II (GlnB, GlnK) Tbd_0808 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 74317699 Nonpathogen - hypothetical protein Tbd_1681 1 None None None 74317737 Common - hypothetical protein Tbd_1719 51 COG3762 COG3762, Predicted membrane protein Function unknown 74317186 Common hscA chaperone protein HscA Tbd_1168 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 74316352 Common - putative cytochrome aa3 oxidase assembly protein,related to CtaA Tbd_0334 50 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 74317055 Common - hypothetical protein Tbd_1037 26 COG1993 COG1993, Uncharacterized conserved protein Function unknown 74316384 Common - hypothetical protein Tbd_0366 11 None None None 74317919 Common - hypothetical protein Tbd_1901 18 COG1801 COG1801, Uncharacterized conserved protein Function unknown 74318462 Common - putative lipoprotein B precursor transmembrane Tbd_2444 24 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 74316624 Common - ATP phosphoribosyltransferase regulatory subunit Tbd_0606 213 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 74318400 Common - Protein of unknown function DUF205 Tbd_2382 170 COG0344 COG0344, Predicted membrane protein Function unknown 74316505 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_0487 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 74317450 Common - type II secretion systen protein G Tbd_1432 95 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74316981 Common - ADP-L-glycero-D-manno-heptose-6-epimerase Tbd_0963 225 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74318340 Nonpathogen - hypothetical protein Tbd_2322 1 None None None 74317534 Common - hypothetical protein Tbd_1516 12 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 74318368 Common - hypothetical protein Tbd_2350 36 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 74316749 Nonpathogen - hypothetical protein Tbd_0731 4 None None None 74318629 Common - Two component Transcriptional regulator, Winged helix family Tbd_2611 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74317912 Common - ABC-type multidrug transporter ATPase Tbd_1894 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 74317811 Common - hypothetical protein Tbd_1793 131 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 74318834 Common - ABC transporter ATPase Tbd_2816 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 74317094 Common - hypothetical protein Tbd_1076 24 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 74316900 Common - rieske iron-sulfur protein 2Fe-2S subunit Tbd_0882 80 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 74316954 Common - adenine specific DNA methylase MOD Tbd_0936 96 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 74318583 Common - putative protein porphyrin biosynthesis Tbd_2565 32 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 74317685 Nonpathogen - hypothetical protein Tbd_1667 2 None None None 74318311 Common - phosphonate metabolism protein PhnJ Tbd_2293 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 74318229 Common ruvB Holliday junction DNA helicase B Tbd_2211 226 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 74316638 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Tbd_0620 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 74316665 Common - serine-type D-ala-D-ala-carboxypeptidase Tbd_0647 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 74317115 Nonpathogen - probable flagellar biosynthetic fliR transmembrane protein Tbd_1097 1 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 74316431 Common - ribosomal protein L29 Tbd_0413 95 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 74318744 Common - probable cytochrome C transmembrane protein Tbd_2726 27 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 74317495 Nonpathogen - hypothetical protein Tbd_1477 1 None None None 74316336 Nonpathogen - hypothetical protein Tbd_0318 2 None None None 74316190 Common - diacylglycerol kinase Tbd_0172 87 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 74318094 Common - transmembrane protein Tbd_2076 31 COG4269 COG4269, Predicted membrane protein Function unknown 74317964 Nonpathogen - hypothetical protein Tbd_1946 2 None None None 74317239 Common - hypothetical protein Tbd_1221 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 74317335 Common - hypothetical protein Tbd_1317 6 None None None 74316418 Common rpsL 30S ribosomal protein S12 Tbd_0400 225 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 74318682 Common - hypothetical protein Tbd_2664 17 None None None 74317038 Common - hypothetical protein Tbd_1020 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 74317524 Common - tetraacyldisaccharide-1-P 4'-kinase Tbd_1506 111 COG2835 COG2835, Uncharacterized conserved protein Function unknown 74318763 Common - transmembrane protein Tbd_2745 10 COG4648 COG4648, Predicted membrane protein Function unknown 74316072 Common - hypothetical protein Tbd_0054 67 COG2928 COG2928, Uncharacterized conserved protein Function unknown 74318757 Common - transcription regulatory protein, ArsR family Tbd_2739 116 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 74316079 Common - lytic murein transglycosylase Tbd_0061 108 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 74318773 Common - hypothetical protein Tbd_2755 14 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 74318379 Common - nucleoside-diphosphate-sugar epimerase Tbd_2361 134 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74316676 Common - ribosomal large subunit pseudouridine synthase A Tbd_0658 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 74318842 Common - tRNA modification GTPase TrmE Tbd_2824 217 COG0486 ThdF, Predicted GTPase General function prediction only 74316371 Nonpathogen - hypothetical protein Tbd_0353 3 None None None 74316771 Common - type II secretory pathway component PulF Tbd_0753 140 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 74316425 Common - ribosomal protein L23 Tbd_0407 208 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 74317015 Common - helicase c2 Tbd_0997 136 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 74318722 Common - hypothetical protein Tbd_2704 197 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 74318332 Common - 6-pyruvoyl tetrahydrobiopterin synthase Tbd_2314 110 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 74316588 Common - DMSO reductase chain A Tbd_0570 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 74317258 Common - transcriptional activator FlhD Tbd_1240 27 None None None 74317928 Nonpathogen - hypothetical protein Tbd_1910 3 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 74318103 Common - GTPase Tbd_2085 239 COG1159 Era, GTPase General function prediction only 74318254 Common - Response regulator receiver domain protein (CheY) Tbd_2236 14 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 74318423 Nonpathogen - hypothetical protein Tbd_2405 1 None None None 74318602 Common - apolipoprotein N-acyltransferase Tbd_2584 163 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 74317163 Common nuoD NADH dehydrogenase subunit D Tbd_1145 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 74317793 Common - GDP-L-fucose synthetase Tbd_1775 200 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74318574 Common - thiamine monophosphate synthase Tbd_2556 188 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 74318634 Common - sulfate permease, SulP family Tbd_2616 156 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 74317212 Nonpathogen - hypothetical protein Tbd_1194 1 None None None 74317909 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Tbd_1891 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 74318020 Common - hypothetical protein Tbd_2002 6 None None None 74316241 Common - thioredoxin Tbd_0223 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 74317744 Common - L-sorbosone dehydrogenase, putative Tbd_1726 69 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 74316875 Common - elongation factor P Tbd_0857 215 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 74317901 Common - hypothetical protein Tbd_1883 6 None None None 74317719 Common - putative ammonium transporter Tbd_1701 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 74318656 Common cbbM ribulose-bisphosphate carboxylase form II Tbd_2638 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 74316487 Common - ATP-dependent DNA helicase RecG Tbd_0469 212 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 74318394 Common rplS 50S ribosomal protein L19 Tbd_2376 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 74316118 Common - Predicted signal transduction protein Tbd_0100 50 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 74317175 Common - hypothetical protein Tbd_1157 37 COG2501 COG2501, Uncharacterized conserved protein Function unknown 74316396 Common - insulinase family protein Tbd_0378 164 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 74318529 Nonpathogen - hypothetical protein Tbd_2511 1 None None None 74316199 Common - acetyl-CoA carboxylase biotin carboxylase subunit Tbd_0181 230 COG0439 AccC, Biotin carboxylase Lipid metabolism 74316754 Common - hypothetical protein Tbd_0736 12 None None None 74317626 Common - flagellar motor switch/type III secretory pathway protein FliN Tbd_1608 123 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 74317853 Nonpathogen - hypothetical protein Tbd_1835 3 COG1416 COG1416, Uncharacterized conserved protein Function unknown 74317137 Common - putative lipoprotein Tbd_1119 13 None None None 74317449 Common - putative heat shock protein, DnaJ family Tbd_1431 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 74316416 Common - DNA-directed RNA polymerase, beta subunit Tbd_0398 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 74317474 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Tbd_1456 199 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74316344 Common - cytochrome c oxidase subunit I Tbd_0326 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 74318204 Common - putative protease Tbd_2186 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 74318522 Common - shikimate 5-dehydrogenase Tbd_2504 221 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 74318372 Common - Two component Transcriptional regulator, Winged helix family Tbd_2354 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74318002 Common - Possible Transcriptional Regulator, TetR family Tbd_1984 135 COG1309 AcrR, Transcriptional regulator Transcription 74316887 Common - nitric oxide reductase activation protein NorQ Tbd_0869 84 COG0714 COG0714, MoxR-like ATPases General function prediction only 74317036 Common - putative lipoprotein Tbd_1018 12 None None None 74318148 Common - A/G-specific adenine glycosylase MutY Tbd_2130 209 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 74317753 Common - universal stress protein Tbd_1735 129 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 74317459 Common - type II secretion system protein G Tbd_1441 13 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74317304 Common - putative 5'-nucleotidase/2' 3'-cyclic phosphodiesterase Tbd_1286 101 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 74316213 Common - TPR repeat Tbd_0195 123 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 74318788 Nonpathogen - hypothetical protein Tbd_2770 1 None None None 74318512 Common - modification methylase HemK Tbd_2494 230 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 74317440 Common - Putative diguanylate phosphodiesterase (EAL domain) Tbd_1422 44 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 74316556 Common - capsule expression protein KpsF/GutQ Tbd_0538 170 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 74316372 Common - hemolysin activation/secretion protein Tbd_0354 43 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 74318179 Nonpathogen - hypothetical protein Tbd_2161 1 None None None 74317926 Common - amidophosphoribosyltransferase Tbd_1908 239 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 74318466 Common - hypothetical protein Tbd_2448 8 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 74318589 Common - Periplasmic Sensor Hybrid Histidine Kinase Tbd_2571 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74317275 Common - Predicted transcriptional regulator Tbd_1257 141 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 74317041 Common - Elongator protein 3/MiaB/NifB Tbd_1023 197 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 74318622 Common - transcriptional regulator, LysR family Tbd_2604 171 COG0583 LysR, Transcriptional regulator Transcription 74317380 Nonpathogen - transcriptional regulator, TetR family Tbd_1362 15 None None None 74316958 Nonpathogen - hypothetical protein Tbd_0940 2 None None None 74316525 Common - serine protease, subtilase family Tbd_0507 148 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 74318501 Common - DsrE protein Tbd_2483 49 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 74317283 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Tbd_1265 182 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74317421 Common - nitrate reductase, alpha subunit Tbd_1403 100 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 74318184 Common - hypothetical protein Tbd_2166 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 74316811 Common - surface antigen (D15) Tbd_0793 161 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 74316785 Nonpathogen - hypothetical protein Tbd_0767 1 None None None 74317974 Nonpathogen - hypothetical protein Tbd_1956 1 None None None 74316292 Common - lipoyl synthase Tbd_0274 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 74316592 Common - hypothetical protein Tbd_0574 118 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 74316951 Common - DEAD/DEAH box helicase Tbd_0933 182 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 74316710 Nonpathogen - hypothetical protein Tbd_0692 1 None None None 74316041 Common - hypothetical protein with TPR repeat Tbd_0023 9 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 74316480 Common - hypothetical protein Tbd_0462 8 None None None 74317892 Common - hypothetical protein Tbd_1874 156 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 74316829 Common - Protein of unknown function DUF152 Tbd_0811 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 74318476 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase bifunctional enzyme Tbd_2458 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 74316837 Nonpathogen - hypothetical protein Tbd_0819 1 None None None 74316628 Common - conserved secreted protein with internal repeats Tbd_0610 3 None None None 74317071 Common - hypothetical protein Tbd_1053 20 COG1416 COG1416, Uncharacterized conserved protein Function unknown 74317350 Common - hypothetical protein Tbd_1332 36 COG5569 COG5569, Uncharacterized conserved protein Function unknown 74318377 Common - hypothetical protein Tbd_2359 118 COG1690 RtcB, Uncharacterized conserved protein Function unknown 74317643 Common - Response regulator receiver domain protein (CheY) Tbd_1625 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74317359 Common - mercuric reductase MerA Tbd_1341 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 74318837 Common - hypothetical protein Tbd_2819 32 COG5519 COG5519, Superfamily II helicase and inactivated derivatives DNA replication, recombination, and repair 74316898 Common - polyprenyl synthetase Tbd_0880 240 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 74318517 Common - Glutaredoxin-related protein Tbd_2499 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 74316303 Common - ATPase Tbd_0285 73 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 74316165 Common - hypothetical protein Tbd_0147 52 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 74318194 Nonpathogen - hypothetical protein Tbd_2176 3 None None None 74317783 Common - ZIP Zinc transporter Tbd_1765 82 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 74316818 Common - hypothetical protein Tbd_0800 21 COG5615 COG5615, Predicted integral membrane protein Function unknown 74316891 Nonpathogen - adenylylsulfate reductase, beta subunit Tbd_0873 14 COG1146 COG1146, Ferredoxin Energy production and conversion 74318561 Common - hypothetical protein Tbd_2543 56 COG2862 COG2862, Predicted membrane protein Function unknown 74318407 Common slmA nucleoid occlusion protein Tbd_2389 60 COG1309 AcrR, Transcriptional regulator Transcription 74316351 Common - probable transmembrane protein Tbd_0333 35 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 74316313 Common - possible capK protein Tbd_0295 69 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 74317317 Common - probable prolin-rich transmembrane protein Tbd_1299 6 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 74318533 Common - hypothetical protein Tbd_2515 10 COG5633 COG5633, Predicted periplasmic lipoprotein General function prediction only 74316108 Common - CBS signal-transduction protein Tbd_0090 97 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 74317777 Common - DNA internalization-related competence protein ComEC/Rec2 Tbd_1759 158 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 74316455 Common - MFS family transporter Tbd_0437 217 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 74318645 Common - alpha,alpha-trehalose-phosphate synthase Tbd_2627 27 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 74317219 Nonpathogen - hypothetical protein Tbd_1201 4 None None None 74317881 Common - hypothetical protein Tbd_1863 3 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 74317723 Common - probable HIT family protein Tbd_1705 235 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 74316185 Common - glutaredoxin family protein Tbd_0167 21 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 74316178 Common cbbG glyceraldehyde-3-phosphate dehydrogenase, type I Tbd_0160 227 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 74316232 Nonpathogen - hypothetical protein Tbd_0214 1 None None None 74317320 Common - type II secretion system protein Tbd_1302 75 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74318004 Common - 2-isopropylmalate synthase Tbd_1986 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 74316064 Common glcE glycolate oxidase FAD binding subunit Tbd_0046 156 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 74317987 Common - hypothetical protein Tbd_1969 5 None None None 74317483 Common - ribose-phosphate pyrophosphokinase Tbd_1465 238 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 74316200 Common - acetyl-CoA biotin carboxyl carrier Tbd_0182 187 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 74316504 Nonpathogen - hypothetical protein Tbd_0486 1 None None None 74318053 Common - putative sulfide dehydrogenase flavocytochrome c oxidoreductase Tbd_2035 87 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 74318736 Common - ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Tbd_2718 141 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 74318816 Common - F0F1 ATP synthase subunit gamma Tbd_2798 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 74316802 Common - methionine aminopeptidase Tbd_0784 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 74317310 Common - putative 5'-nucleotidase/2' 3'-cyclic phosphodiesterase Tbd_1292 133 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 74318086 Common - DnaB helicase Tbd_2068 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 74317768 Common - Multi-sensor Signal Transduction Histidine Kinase Tbd_1750 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74317426 Common - sulfite reductase gamma chain Tbd_1408 58 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 74316616 Common engA GTP-binding protein EngA Tbd_0598 240 COG1160 COG1160, Predicted GTPases General function prediction only 74318155 Common - esterase/lipase/thioesterase family active site Tbd_2137 61 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 74316747 Common - hypothetical protein Tbd_0729 17 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 74318177 Common - Predicted signal transduction protein containing EAL and modified HD-GYP domains Tbd_2159 43 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 74317086 Common - hypothetical protein Tbd_1068 9 None None None 74317831 Nonpathogen - hypothetical protein Tbd_1813 1 None None None 74317373 Common - hypothetical protein Tbd_1355 34 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 74318080 Common - glucokinase Tbd_2062 90 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 74316520 Common - cation-transporting ATPase, E1-E2 type Tbd_0502 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 74317077 Common - rRNA (guanine-N1-)-methyltransferase, putative Tbd_1059 67 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 74317340 Nonpathogen - hypothetical protein Tbd_1322 1 None None None 74318285 Common - Transcriptional Regulator, MerR family Tbd_2267 127 COG0789 SoxR, Predicted transcriptional regulators Transcription 74316048 Nonpathogen - hypothetical protein Tbd_0030 1 None None None 74318234 Common - ROK family protein Tbd_2216 100 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 74318508 Nonpathogen - hypothetical protein Tbd_2490 4 None None None 74317132 Common - Cation efflux protein Tbd_1114 218 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 74317463 Common - putative heat shock protein Tbd_1445 150 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 74316756 Common - putative LPS biosynthesis related glycosyltransferase Tbd_0738 37 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 74317859 Common - pterin 4 alpha carbinolamine dehydratase Tbd_1841 97 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 74318708 Common - Two Component Transcriptional Regulator, Fis family Tbd_2690 212 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 74318633 Common - hypothetical protein Tbd_2615 186 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 74318116 Common - glycine cleavage T-protein (aminomethyl transferase) Tbd_2098 149 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 74317935 Nonpathogen - hypothetical protein Tbd_1917 1 None None None 74317568 Common - malonyl CoA-acyl carrier protein transacylase Tbd_1550 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 74316168 Nonpathogen - hypothetical protein Tbd_0150 6 None None None 74318028 Common - hypothetical protein Tbd_2010 6 None None None 74317520 Common - 6-phosphofructokinase Tbd_1502 148 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 74317841 Nonpathogen - hypothetical protein Tbd_1823 1 None None None 74317571 Common rpmF 50S ribosomal protein L32 Tbd_1553 95 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 74316140 Common ddl D-alanine--D-alanine ligase Tbd_0122 214 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 74317126 Common - hypothetical protein Tbd_1108 14 None None None 74317114 Common - flagellar biosynthetic protein FliQ Tbd_1096 17 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 74317284 Common - probable TonB-dependent iron complex outermembrane receptor protein Tbd_1266 115 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 74318592 Common - esterase Tbd_2574 50 COG3150 COG3150, Predicted esterase General function prediction only 74316275 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Tbd_0257 210 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 74317678 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Tbd_1660 181 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 74317001 Common - adenylyl cyclase class-3/4/guanylyl cyclase Tbd_0983 91 COG4252 COG4252, Predicted transmembrane sensor domain Signal transduction mechanisms 74318674 Common - Chromate transporter Tbd_2656 99 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 74316280 Common - hypothetical protein Tbd_0262 45 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 74317630 Common - flagellar biosynthesis protein FliR Tbd_1612 112 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 74317166 Common nuoG NADH dehydrogenase subunit G Tbd_1148 195 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 74317876 Common - peptidase A8, signal peptidase II Tbd_1858 157 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74317832 Nonpathogen - hypothetical protein Tbd_1814 1 None None None 74317084 Nonpathogen - hypothetical protein Tbd_1066 1 None None None 74316991 Nonpathogen - hypothetical protein Tbd_0973 19 COG5316 COG5316, Uncharacterized conserved protein Function unknown 74317598 Common - hypothetical protein Tbd_1580 73 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 74317349 Common - hypothetical protein Tbd_1331 12 None None None 74316121 Common - transcriptional regulator PyrR, putative Tbd_0103 101 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 74317943 Common - flavin reductase-like protein Tbd_1925 76 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 74318759 Nonpathogen - hypothetical protein Tbd_2741 5 COG3462 COG3462, Predicted membrane protein Function unknown 74316578 Common - putative additional subunit of nitric oxide reductase (Nor) complex, membrane protein Tbd_0560 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 74316669 Common - hypothetical protein Tbd_0651 41 COG3832 COG3832, Uncharacterized conserved protein Function unknown 74318454 Common - 3-methyladenine DNA glycosylase II Tbd_2436 113 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 74318767 Common - hypothetical protein Tbd_2749 15 None None None 74316491 Common - guanylate kinase Tbd_0473 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 74316790 Common - GTP-binding protein TypA Tbd_0772 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 74318640 Common cbbQ1 rubisco activation protein CbbQ Tbd_2622 97 COG0714 COG0714, MoxR-like ATPases General function prediction only 74317748 Nonpathogen - hypothetical protein Tbd_1730 1 None None None 74316976 Nonpathogen - hypothetical protein Tbd_0958 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 74318523 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase Tbd_2505 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 74316267 Common - ABC-type transport system periplasmic component Tbd_0249 73 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 74317214 Common - outer membrane lipoprotein Tbd_1196 73 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 74318097 Common - preprotein translocase protein SecD Tbd_2079 216 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 74316573 Common - putative nitric oxide reductase activation protein Tbd_0555 44 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 74318126 Common - ATP-binding protein involved in chromosome partitioning Tbd_2108 233 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 74317023 Common - 2',5' RNA ligase Tbd_1005 51 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 74318550 Common - Secretion protein HlyD Tbd_2532 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 74318035 Common - electron transport complex protein RnfC Tbd_2017 74 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 74316465 Common - putative neutral zinc metallopeptidase Tbd_0447 85 COG2321 COG2321, Predicted metalloprotease General function prediction only 74316096 Common - regulator of nitric oxide reductase transcription Tbd_0078 68 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 74317807 Common - putative alpha-L-arabinofuranosidase Tbd_1789 25 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 74316865 Common - methionine sulfoxide reductase A Tbd_0847 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 74316403 Common - outer membrane lipoprotein LolB Tbd_0385 39 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 74317662 Nonpathogen - hypothetical protein Tbd_1644 1 None None None 74316296 Common - hypothetical protein Tbd_0278 80 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 74317513 Common - Metal dependent phosphohydrolase, HD region Tbd_1495 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 74318334 Common - rubredoxin Tbd_2316 119 COG1773 COG1773, Rubredoxin Energy production and conversion 74316564 Common - type IV pilus assembly protein PilC Tbd_0546 141 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 74317644 Common - hypothetical protein Tbd_1626 6 None None None 74318516 Common - hypothetical protein Tbd_2498 13 None None None 74316584 Common - transmembrane proetin, twin-arginine translocation pathway signal Tbd_0566 36 COG5501 COG5501, Predicted secreted protein Function unknown 74318568 Common - twitching motility protein PilI Tbd_2550 15 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 74316361 Nonpathogen - hypothetical protein Tbd_0343 2 COG5456 COG5456, Predicted integral membrane protein linked to a cation pump Inorganic ion transport and metabolism 74316075 Common - hypothetical protein Tbd_0057 131 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 74317198 Common - RNA polymerase sigma-70 factor Tbd_1180 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 74317555 Common - molecular chaperone protein GrpE Tbd_1537 219 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 74316868 Common - glutaminyl-tRNA synthetase Tbd_0850 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 74316841 Common - nitric-oxide reductase subunit B Tbd_0823 87 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 74318807 Common - probable thiol:disulfide interchange protein Tbd_2789 138 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 74317995 Common - formyltetrahydrofolate deformylase Tbd_1977 221 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 74316933 Nonpathogen - hypothetical protein Tbd_0915 6 None None None 74316205 Common - cytochrome c oxidase Tbd_0187 62 COG2863 COG2863, Cytochrome c553 Energy production and conversion 74317580 Common - putative hydrolase Tbd_1562 194 COG0546 Gph, Predicted phosphatases General function prediction only 74318135 Common - hypothetical protein Tbd_2117 18 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 74316441 Common rpmD 50S ribosomal protein L30 Tbd_0423 106 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 74316326 Common - glycosyltransferase Tbd_0308 36 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 74316369 Common - Transcriptional Regulator, LuxR family Tbd_0351 95 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 74317706 Common - hypothetical protein Tbd_1688 5 None None None 74318830 Common - allophanate hydrolase subunit 2 Tbd_2812 113 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 74316087 Common - arginase Tbd_0069 66 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 74318725 Common - hemolysin-like protein Tbd_2707 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 74317048 Common - hypothetical protein Tbd_1030 95 COG2353 COG2353, Uncharacterized conserved protein Function unknown 74316965 Common - N-ethylammeline chlorohydrolase Tbd_0947 172 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 74316822 Common - hypothetical protein Tbd_0804 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 74316137 Common - N-acetylglucosaminyltransferase, MurG Tbd_0119 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 74316946 Common - transposase InsF for insertion sequence IS3A/B/C/D/E/fA Tbd_0928 147 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 74316545 Nonpathogen - hypothetical protein Tbd_0527 8 COG4769 COG4769, Predicted membrane protein Function unknown 74318572 Common - probable rubredoxin protein Tbd_2554 111 COG1773 COG1773, Rubredoxin Energy production and conversion 74317923 Common - UDP-2,3-diacylglucosamine hydrolase Tbd_1905 75 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 74318256 Nonpathogen - hypothetical protein Tbd_2238 1 None None None 74318473 Common - large-conductance mechanosensitive channel Tbd_2455 136 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 74318398 Common - hypothetical protein Tbd_2380 11 None None None 74316902 Common - hypothetical protein Tbd_0884 14 None None None 74317941 Common - putative transporter Tbd_1923 74 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 74317735 Common - transcriptional regulator Tbd_1717 192 COG0583 LysR, Transcriptional regulator Transcription 74318349 Common - thiol:disulfide interchange protein DsbC Tbd_2331 74 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 74316341 Common - dethiobiotin synthase Tbd_0323 105 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 74316873 Common - Possible Cold-shock DNA-binding domain protein Tbd_0855 182 COG1278 CspC, Cold shock proteins Transcription 74316918 Common - hypothetical protein Tbd_0900 18 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 74316398 Common - panththeine-phosphate adenylyltransferase Tbd_0380 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 74318206 Common - putative 2-nitropropane dioxygenase Tbd_2188 80 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 74318464 Common - hypothetical protein Tbd_2446 30 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 74318278 Common - hypothetical protein Tbd_2260 8 None None None 74317400 Common - hydrogenase expression/formation protein HypA Tbd_1382 83 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 74317306 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Tbd_1288 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74316731 Common - periplasmic protein TonB Tbd_0713 53 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 74316824 Common - succinyl-CoA ligase, alpha subunit Tbd_0806 214 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 74316983 Common - DNA repair protein RadA Tbd_0965 206 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 74318266 Common - hypothetical protein Tbd_2248 29 None None None 74317244 Common - probable sugar kinase, FGGY family Tbd_1226 104 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 74317399 Common - hydrogenase expression/formation protein (HUPF/HYPC) Tbd_1381 48 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 74318190 Common - hypothetical protein Tbd_2172 20 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 74317951 Common - hypothetical protein Tbd_1933 70 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74317692 Common - Histone-like DNA-binding protein Tbd_1674 208 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 74317493 Common - hypothetical protein Tbd_1475 33 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 74318540 Common - lipid A biosynthesis lauroyl acyltransferase Tbd_2522 113 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 74317918 Common - ABC transporter ATPase Tbd_1900 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 74317092 Nonpathogen - hypothetical protein Tbd_1074 1 None None None 74317639 Common - 5'-nucleotidase/2' 3'-cyclic phosphodiesterase Tbd_1621 138 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 74318318 Common - Phosphonate-binding periplasmic protein Tbd_2300 98 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 74316421 Common - elongation factor Tu Tbd_0403 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 74318627 Common - sulphate anion transporter Tbd_2609 162 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 74318492 Nonpathogen - molybdopterin oxidoreductase, membrane subunit Tbd_2474 8 COG5557 COG5557, Polysulphide reductase Energy production and conversion 74318713 Common - putative protein-L-isoaspartate o-methyltransferase Tbd_2695 145 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 74316956 Common - hypothetical protein Tbd_0938 18 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 74318358 Common ksgA dimethyladenosine transferase Tbd_2340 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 74316562 Nonpathogen - hypothetical protein Tbd_0544 2 None None None 74318160 Common - thioredoxin-related protein Tbd_2142 13 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 74318742 Common - 5-formyltetrahydrofolate cyclo-ligase family protein Tbd_2724 183 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 74317060 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC and GAF sensor(s) Tbd_1042 192 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74318215 Common recA recombinase A Tbd_2197 232 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 74318325 Common - conserved hypothetical protein-putative acetyltransferase Tbd_2307 30 COG0456 RimI, Acetyltransferases General function prediction only 74318167 Common - putative lipase Tbd_2149 107 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 74316859 Common - hypothetical protein Tbd_0841 49 COG3737 COG3737, Uncharacterized conserved protein Function unknown 74317135 Common - acyl carrier protein phosphodiesterase Tbd_1117 99 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 74317202 Common - succinate dehydrogenase Tbd_1184 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 74318010 Nonpathogen - hypothetical protein Tbd_1992 4 COG4831 COG4831, Uncharacterized conserved protein Function unknown 74317149 Common - hypothetical protein Tbd_1131 90 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 74317457 Common - type II secretion system protein D Tbd_1439 136 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 74316804 Common tsf elongation factor Ts Tbd_0786 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 74318585 Common - uroporphyrinogen-III synthase Tbd_2567 59 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 74318124 Common - lysine decarboxylase Tbd_2106 86 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 74316536 Common - adenylosuccinate lyase Tbd_0518 230 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 74317878 Common - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase, LytB protein Tbd_1860 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 74318056 Nonpathogen - putative outer membrane protein Tbd_2038 1 None None None 74318689 Common - Periplasmic Sensor Hybrid Histidine Kinase Tbd_2671 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74316974 Common rpsA 30S ribosomal protein S1 Tbd_0956 223 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 74317771 Nonpathogen - hypothetical protein Tbd_1753 1 None None None 74316035 Common - proline rich signal peptide protein Tbd_0017 19 None None None 74317059 Common - beta lactamase precursor Tbd_1041 104 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 74318247 Common cbbZ phosphoglycolate phosphatase Tbd_2229 159 COG0546 Gph, Predicted phosphatases General function prediction only 74317871 Common - hypothetical protein Tbd_1853 19 None None None 74318771 Common - 3-oxoacyl-(acyl carrier protein) synthase I Tbd_2753 208 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 74318438 Common - Pilus retraction protein PilT Tbd_2420 173 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 74317866 Common - hypothetical protein Tbd_1848 53 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 74316273 Common pyrE orotate phosphoribosyltransferase Tbd_0255 138 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 74317756 Common - putative transmembrane protein Tbd_1738 92 COG2081 COG2081, Predicted flavoproteins General function prediction only 74316879 Common - hypothetical protein Tbd_0861 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 74316738 Common - hypothetical protein Tbd_0720 27 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 74318208 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein Tbd_2190 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 74316239 Common - quinolinate synthetase Tbd_0221 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 74317407 Common - nitrous-oxide reductase Tbd_1389 40 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 74317780 Common - hypothetical protein Tbd_1762 126 COG0432 COG0432, Uncharacterized conserved protein Function unknown 74318798 Common - hypothetical protein Tbd_2780 32 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 74316726 Common - probable thiamine biosynthesis lipoprotein apbE precursor transmembrane Tbd_0708 85 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 74316697 Common - Possible Cold-shock DNA-binding domain protein Tbd_0679 182 COG1278 CspC, Cold shock proteins Transcription 74318547 Common - hypothetical protein Tbd_2529 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 74318434 Common - hypothetical protein Tbd_2416 71 None None None 74317439 Nonpathogen - hypothetical protein Tbd_1421 1 None None None 74316271 Common - putative transport transmembrane protein Tbd_0253 104 None None None 74316463 Common - endonuclease / exonuclease / phosphatase family protein Tbd_0445 65 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 74317527 Common - biopolymer transport exbD-related transmembrane protein Tbd_1509 84 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 74317377 Common - ABC transporter ATPase Tbd_1359 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 74318636 Nonpathogen - hypothetical protein Tbd_2618 1 None None None 74318324 Common - hypothetical protein Tbd_2306 25 COG3832 COG3832, Uncharacterized conserved protein Function unknown 74317899 Common - alpha-D-glucose-1-phosphate cytidylyltransferase Tbd_1881 164 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 74318105 Common - possible transmembrane protein Tbd_2087 15 COG5069 SAC6, Ca2+-binding actin-bundling protein fimbrin/plastin (EF-Hand superfamily) Cytoskeleton 74316289 Common - putative dioxygenase ferredoxin subunit Tbd_0271 78 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 74316990 Common - Predicted signal transduction protein containing EAL and modified HD-GYP domains Tbd_0972 4 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 74316408 Common - translation-associated GTPase Tbd_0390 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 74318396 Common - tyrosine recombinase XerD Tbd_2378 234 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 74316197 Common - hypothetical protein Tbd_0179 20 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 74316602 Nonpathogen - hypothetical protein Tbd_0584 2 None None None 74317749 Common - NAD(P)H-flavin oxidoreductase Tbd_1731 33 COG0778 NfnB, Nitroreductase Energy production and conversion 74317418 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Tbd_1400 136 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 74318414 Common - Secretion protein HlyD Tbd_2396 141 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 74317654 Common - flagellar basal-body rod protein FlgC Tbd_1636 123 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 74318651 Common - hypothetical protein Tbd_2633 13 COG3427 COG3427, Uncharacterized conserved protein Function unknown 74317742 Common - Ribosomal-protein-alanine acetyltransferase Tbd_1724 175 COG0456 RimI, Acetyltransferases General function prediction only 74317177 Common - MutS 1 protein Tbd_1159 200 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 74317298 Common - hypothetical protein Tbd_1280 227 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 74317101 Common - ABC transport system ATPase component Tbd_1083 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 74317796 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Tbd_1778 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 74318510 Common hemA glutamyl-tRNA reductase Tbd_2492 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 74316091 Common - Possible Transcriptional Regulator, AsnC family Tbd_0073 49 COG1522 Lrp, Transcriptional regulators Transcription 74318084 Nonpathogen - hypothetical protein Tbd_2066 1 None None None 74317151 Common - peptidase M41, FtsH Tbd_1133 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 74317447 Common - thiol-disulfide isomerase/thioredoxin Tbd_1429 65 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 74317424 Common - nitrate reductase, gamma subunit Tbd_1406 58 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 74318143 Common - tRNA (guanine-N(7)-)-methyltransferase Tbd_2125 176 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 74316100 Common - hypothetical protein Tbd_0082 99 COG0679 COG0679, Predicted permeases General function prediction only 74317903 Common - 3-dehydroquinate synthase Tbd_1885 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 74316143 Common - cell division protein FtsZ Tbd_0125 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 74316488 Common - YjgF-like protein Tbd_0470 174 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 74317713 Nonpathogen - hypothetical protein Tbd_1695 2 None None None 74318049 Common - NAD kinase Tbd_2031 241 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 74316554 Common - hypothetical protein Tbd_0536 13 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 74316911 Common - lysyl-tRNA synthetase, class-2 Tbd_0893 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 74318146 Nonpathogen - hypothetical protein Tbd_2128 1 None None None 74317236 Common - probable transmembrane protein Tbd_1218 39 COG3671 COG3671, Predicted membrane protein Function unknown 74317251 Common - hypothetical protein Tbd_1233 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 74316482 Common - chorismate:pyruvate lyase, 4-hydroxybenzoate synthetase Tbd_0464 45 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 74318308 Common - amidohydrolase-like protein Tbd_2290 60 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 74316411 Common - NusG antitermination factor Tbd_0393 215 COG0250 NusG, Transcription antiterminator Transcription 74316215 Common - Two Component Transcriptional Regulator, Fis family Tbd_0197 176 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 74318658 Common - probable high affinity sulfate transporter (SulP) Tbd_2640 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 74318421 Common - hypothetical protein Tbd_2403 35 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 74318555 Common - hypothetical protein Tbd_2537 15 None None None 74318680 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit Tbd_2662 194 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 74316070 Common - glycine cleavage system transcriptional repressor Tbd_0052 40 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 74317536 Common - hypothetical protein Tbd_1518 17 COG3945 COG3945, Uncharacterized conserved protein Function unknown 74318620 Common - hypothetical protein Tbd_2602 100 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 74316158 Common - hypothetical protein Tbd_0140 66 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 74318391 Common - Signal recognition particle protein Tbd_2373 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 74316925 Common - conserved hypothetical protein containing BNR repeat Tbd_0907 18 None None None 74317266 Common - putative flagellar biosynthesis protein FlhG Tbd_1248 85 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 74317189 Common - hypothetical protein Tbd_1171 8 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 74317412 Common - putative lipoprotein involved in nitrous oxide reduction Tbd_1394 33 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 74316513 Common - putative monovalent cation/H+ antiporter subunit D Tbd_0495 172 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 74318600 Common pyrB aspartate carbamoyltransferase catalytic subunit Tbd_2582 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 74318009 Common - acetolactate synthase, large subunit Tbd_1991 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 74316251 Nonpathogen - hypothetical protein Tbd_0233 2 None None None 74318593 Common - ribonuclease II Tbd_2575 138 COG0557 VacB, Exoribonuclease R Transcription 74317962 Nonpathogen - hypothetical protein Tbd_1944 1 None None None 74317697 Common - site-specific recombinase, phage integrase family Tbd_1679 126 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 74318040 Common - hypothetical protein Tbd_2022 23 None None None 74317193 Common - glucose-1-phosphate adenylyltransferase Tbd_1175 162 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 74318073 Common - aspartate alpha-decarboxylase Tbd_2055 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 74316636 Common - phosphoenolpyruvate synthase Tbd_0618 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 74316098 Common - hypothetical protein Tbd_0080 12 None None None 74317543 Common - tryptophanyl-tRNA synthetase Tbd_1525 235 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74316335 Common - hypothetical protein Tbd_0317 168 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 74318449 Common - putative thioredoxin Tbd_2431 156 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 74316535 Common recR recombination protein RecR Tbd_0517 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 74316863 Common - hypothetical protein Tbd_0845 59 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 74317119 Common - DEAD/DEAH box helicase Tbd_1101 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 74316541 Nonpathogen - hypothetical protein Tbd_0523 1 None None None 74317122 Common - conserved hyothetical protein Tbd_1104 151 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 74316660 Common - Cytochrome C oxidase, mono-heme subunit/FixO Tbd_0642 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 74316224 Common - type IV pilus assembly protein PilQ Tbd_0206 137 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 74316671 Common - hypothetical protein Tbd_0653 34 None None None 74317628 Common fliP flagellar biosynthesis protein FliP Tbd_1610 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 74316858 Common - putative cytochrome c5 Tbd_0840 43 COG3245 CycB, Cytochrome c5 Energy production and conversion 74317046 Common - Transcriptional Regulator, MarR family Tbd_1028 115 COG1846 MarR, Transcriptional regulators Transcription 74316725 Common - probable transmembrane protein Tbd_0707 7 None None None 74316678 Common - chemotaxis sensory transducer Tbd_0660 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 74316229 Nonpathogen - hypothetical protein Tbd_0211 1 None None None 74316250 Common - hypothetical protein Tbd_0232 177 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 74316082 Common - putative cytochrome C precursor Tbd_0064 60 COG2863 COG2863, Cytochrome c553 Energy production and conversion 74316128 Common - hypothetical protein Tbd_0110 143 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 74317689 Common - oligopeptide ABC transporter periplasmic component Tbd_1671 157 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 74316332 Common - hypothetical protein Tbd_0314 34 None None None 74316234 Common - Two component Transcriptional regulator, Winged helix family Tbd_0216 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74318617 Nonpathogen - hypothetical protein Tbd_2599 4 None None None 74316047 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Tbd_0029 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 74316265 Common - ABC transport system permease protein Tbd_0247 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 74316126 Common - hypothetical protein Tbd_0108 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 74316575 Nonpathogen - hypothetical protein Tbd_0557 3 None None None 74317801 Common - glucosyltransferase protein Tbd_1783 151 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 74317112 Common - probable Flagellar protein FliO Tbd_1094 35 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 74317004 Nonpathogen - hypothetical protein Tbd_0986 6 COG3439 COG3439, Uncharacterized conserved protein Function unknown 74317160 Common nuoA NADH dehydrogenase I chain A Tbd_1142 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 74318013 Common - putative transmembrane protein Tbd_1995 24 COG1714 COG1714, Predicted membrane protein/domain Function unknown 74318083 Common - potassium uptake protein Tbd_2065 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 74316188 Common - outer membrane lipoprotein, putative Tbd_0170 5 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 74317844 Nonpathogen - hypothetical protein Tbd_1826 1 None None None 74318748 Common - dihydroxy-acid dehydratase Tbd_2730 212 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 74318133 Nonpathogen - RND multidrug efflux membrane fusion protein MexE precursor Tbd_2115 1 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 74318388 Common - type IV pilus assembly protein, PilB Tbd_2370 217 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 74318381 Common - threonine dehydratase I Tbd_2363 230 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 74318815 Common - F0F1 ATP synthase subunit beta Tbd_2797 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 74317156 Common - phosphate transport system permease protein 2 Tbd_1138 230 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 74318037 Common - Electron transport complex, RnfABCDGE type, G subunit Tbd_2019 60 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 74316621 Common - HflK Tbd_0603 203 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 74317703 Common - hypothetical protein Tbd_1685 13 None None None 74318823 Common - chromosome partitioning protein ParB Tbd_2805 184 COG1475 Spo0J, Predicted transcriptional regulators Transcription 74317268 Common motC flagellar motor protein Tbd_1250 103 COG1291 MotA, Flagellar motor component Cell motility and secretion 74318107 Common - GTP-binding protein LepA Tbd_2089 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 74316448 Common - DNA-directed RNA polymerase subunit alpha Tbd_0430 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 74317565 Common - 3-oxoacyl-(acyl carrier protein) synthase II Tbd_1547 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 74318113 Common - RNA polymerase sigma factor RpoE Tbd_2095 174 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 74316607 Common - cell cycle protein MesJ Tbd_0589 225 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 161899033 Common mnmC 5-methylaminomethyl-2-thiouridine methyltransferase Tbd_1641 76 COG4121 COG4121, Uncharacterized conserved protein Function unknown 74316367 Nonpathogen - hypothetical protein Tbd_0349 1 None None None 74318231 Common - DNA recombination protein, RuvA Tbd_2213 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 74318663 Common - carboxysome shell protein CsoS1A Tbd_2645 46 COG4577 CcmK, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 74318595 Common cbbF fructose-1,6-bisphosphatase Tbd_2577 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 74317638 Common - chemotaxis sensory transducer Tbd_1620 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 74318805 Common dsbG disulfide isomerase/thiol-disulfide oxidase Tbd_2787 37 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 74317933 Common - N-(5'phosphoribosyl)anthranilate isomerase Tbd_1915 199 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 74318716 Common - probable 3-deoxy-D-manno-octulosonic-acid transferase transmembrane protein Tbd_2698 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 74316478 Common - biotin--acetyl-CoA-carboxylase ligase Tbd_0460 215 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 74318643 Common cbbR1 transcriptional regulator Tbd_2625 193 COG0583 LysR, Transcriptional regulator Transcription 74318237 Common - hypothetical protein Tbd_2219 14 None None None 74317382 Nonpathogen - hypothetical protein Tbd_1364 7 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 74316796 Common - 5'-methylthioadenosine phosphorylase Tbd_0778 147 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 74317286 Common - Multi-sensor Hybrid Histidine Kinase Tbd_1268 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74317170 Common nuoK NADH dehydrogenase subunit K Tbd_1152 163 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 74316282 Common - Rod shape-determining protein RodA Tbd_0264 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 74316931 Nonpathogen - hypothetical protein Tbd_0913 1 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 74317503 Nonpathogen - hypothetical protein Tbd_1485 1 None None None 74316569 Common - Two Component Transcriptional Regulator, Fis family Tbd_0551 182 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 74316474 Common - HesB-like protein Tbd_0456 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 74317936 Common - hypothetical protein Tbd_1918 37 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 74318468 Common - possible transmembrane protein Tbd_2450 23 COG5473 COG5473, Predicted integral membrane protein Function unknown 74316848 Common - hypothetical protein Tbd_0830 36 COG4544 COG4544, Uncharacterized conserved protein Function unknown 74316496 Common - putative deoxyribonucleotide triphosphate pyrophosphatase Tbd_0478 236 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 74318769 Common - probable transmembrane protein Tbd_2751 100 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 74317828 Common - C-5 cytosine-specific DNA methylase Tbd_1810 43 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 74317980 Common - hypothetical protein Tbd_1962 4 None None None 74316736 Common - iron transporter Tbd_0718 50 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 74317153 Common - phosphoglucosamine mutase Tbd_1135 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 74317461 Common - hypothetical protein Tbd_1443 10 None None None 74318100 Common - hypothetical protein Tbd_2082 12 None None None 74317235 Common - hypothetical protein Tbd_1217 71 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 74317646 Common flgK flagellar hook-associated protein FlgK Tbd_1628 100 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 74316996 Common - ABC-type transport system periplasmic component Tbd_0978 21 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 74318711 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_2693 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 74318067 Common - putative Fe3+-siderophores transport system ATPase Tbd_2049 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 74318652 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_2634 196 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 74318170 Common - peptidyl-prolyl cis-trans isomerase Tbd_2152 153 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 74316632 Nonpathogen - glycosyltransferase Tbd_0614 16 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74316761 Common - glycosyltransferase Tbd_0743 56 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74318200 Common - putative dioxygenase related to 2-nitropropane dioxygenase Tbd_2182 104 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 74318317 Common - ABC phosphate/phosphonate transport system ATPase Tbd_2299 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 74316851 Common - hypothetical protein Tbd_0833 103 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 74317346 Common - Secretion protein HlyD Tbd_1328 159 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 74317062 Common - adenosylcobinamide-phosphate synthase Tbd_1044 42 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 74317141 Common - Possible Ferric uptake regulator (FUR) family Tbd_1123 193 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 74317898 Common - CDP-glucose 4,6-dehydratase Tbd_1880 202 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74317857 Common - oligoribonuclease Tbd_1839 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 74316170 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Tbd_0152 187 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74317012 Common - probable ubiquinone biosynthesis protein Tbd_0994 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 74317300 Common - rhodanese-like protein Tbd_1282 191 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 74316938 Nonpathogen - hypothetical protein Tbd_0920 1 None None None 74316667 Nonpathogen - hypothetical protein Tbd_0649 4 None None None 74318487 Common - putative efflux pump/antiporter Tbd_2469 204 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 74317225 Nonpathogen - hypothetical protein Tbd_1207 1 None None None 74317891 Common - putative UDP-glucose 4-epimerase Tbd_1873 220 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74317469 Common - hypothetical protein Tbd_1451 11 None None None 74317945 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_1927 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 74316460 Common aspS aspartyl-tRNA synthetase Tbd_0442 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74316967 Common - phosphoserine aminotransferase Tbd_0949 114 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 74317711 Common - hypothetical protein Tbd_1693 30 None None None 74317470 Common - hypothetical protein Tbd_1452 4 None None None 74317613 Common - hypothetical protein Tbd_1595 14 None None None 74316115 Common - serine protease, trypsin family Tbd_0097 128 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 74318176 Common - hypothetical protein Tbd_2158 46 COG1656 COG1656, Uncharacterized conserved protein Function unknown 74317021 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol synthase Tbd_1003 195 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 74317371 Nonpathogen - hypothetical protein Tbd_1353 1 None None None 74317480 Common - small-conductance mechanosensitive channel protein Tbd_1462 162 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 74317425 Common - Sulfide:quinone oxidoreductase Tbd_1407 122 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 74317883 Common - pilus assembly protein Tbd_1865 67 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 74317088 Nonpathogen - hypothetical protein Tbd_1070 1 None None None 74316514 Common - putative monovalent cation/H+ antiporter subunit C Tbd_0496 100 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 74316357 Common - Cytochrome C oxidase, mono-heme subunit/FixO Tbd_0339 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 74317607 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_1589 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 74316744 Common - Cation efflux protein Tbd_0726 133 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 74317044 Common - molybdopterin converting factor, subunit 1 Tbd_1026 74 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 74317277 Common - CmpX protein Tbd_1259 19 None None None 74316816 Common - lipid-A-disaccharide synthase Tbd_0798 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 74317668 Common - rhodanese-like protein Tbd_1650 8 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 74316547 Common - hypothetical protein Tbd_0529 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 74317861 Nonpathogen - hypothetical protein Tbd_1843 7 COG1416 COG1416, Uncharacterized conserved protein Function unknown 74317834 Nonpathogen - hypothetical protein Tbd_1816 1 None None None 74318845 Common - ribosomal protein L34 Tbd_2827 198 None None None 74318552 Common - cobW protein Tbd_2534 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 74318185 Common ecaA carbonic anhydrase Tbd_2167 52 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 74317981 Nonpathogen - hypothetical protein Tbd_1963 1 None None None 74316453 Common - pseudouridine synthase, Rsu Tbd_0435 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 74317586 Common - excinuclease ABC subunit B Tbd_1568 230 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 74317290 Common - hypothetical protein Tbd_1272 87 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 74317327 Common - sulfite reductase, dissimilatory-type alpha subunit Tbd_1309 36 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 74317656 Common flgA flagellar basal body P-ring biosynthesis protein FlgA Tbd_1638 31 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 74316595 Common valS valyl-tRNA synthetase Tbd_0577 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74316106 Common - sodium:solute symporter family protein Tbd_0088 163 COG4147 DhlC, Predicted symporter General function prediction only 74316765 Common - hypothetical protein Tbd_0747 103 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 74316294 Common - ABC-2 type transporter, NodJ Tbd_0276 144 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 74317824 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Tbd_1806 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74317006 Common - transport system ATPase Tbd_0988 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 74318152 Common - branched-chain amino acid aminotransferase Tbd_2134 217 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 74316712 Common - ribosomal protein S15 Tbd_0694 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 74316051 Common - hypothetical protein Tbd_0033 199 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 74316179 Common pgk phosphoglycerate kinase Tbd_0161 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 74318405 Common - DNA primase Tbd_2387 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 74316783 Common - type II secretory pathway component ATPase Tbd_0765 71 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 74318701 Common - hypothetical protein Tbd_2683 29 COG3950 COG3950, Predicted ATP-binding protein involved in virulence General function prediction only 74317854 Common - Sigma-24 (FecI) Tbd_1836 147 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 74316701 Common - hypothetical protein Tbd_0683 109 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 74317035 Nonpathogen - hypothetical protein Tbd_1017 2 None None None 74316144 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase Tbd_0126 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 74318348 Common - hypothetical protein Tbd_2330 46 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 74318351 Common - ubiquinone biosynthesis hydroxylase Tbd_2333 114 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 74317596 Common - probable MFS transporter Tbd_1578 128 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 74316610 Common - putative pilus assembly protein PilF, TPR repeat Tbd_0592 96 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 74316717 Common - hypothetical protein Tbd_0699 160 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 74317442 Common - Putative Transcriptional Regulator, ArsR family Tbd_1424 67 COG0640 ArsR, Predicted transcriptional regulators Transcription 74316132 Common - UDP-N-acetylmuramyl-tripeptide synthetase Tbd_0114 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 74316067 Common - hypothetical protein Tbd_0049 44 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 74318673 Common - NADH dehydrogenase Tbd_2655 208 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 74318017 Common - heat shock protein DnaJ Tbd_1999 220 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 74317139 Common - alpha-ribazole-5`-phosphate phosphatase CobC, putative Tbd_1121 157 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 74318570 Common - Response regulator receiver domain protein (CheY) Tbd_2552 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74316298 Common - hypothetical protein Tbd_0280 39 COG1694 MazG, Predicted pyrophosphatase General function prediction only 74316594 Common - putative long-chain fatty acid transport protein Tbd_0576 32 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 74318071 Common - ketopantoate hydroxymethyltransferase Tbd_2053 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 74317072 Nonpathogen - hypothetical protein Tbd_1054 2 None None None 74317246 Common - Chromosome segregation protein SMC Tbd_1228 182 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 74318539 Common - S-adenosylmethionine synthetase Tbd_2521 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 74317916 Common - putative ABC transporter substrate-binding protein Tbd_1898 109 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 74317816 Common - hypothetical protein Tbd_1798 20 None None None 74316027 Nonpathogen - hypothetical protein Tbd_0009 1 None None None 74316277 Common - glutamyl-tRNA(Gln) amidotransferase C subunit Tbd_0259 113 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 74316388 Nonpathogen - hypothetical protein Tbd_0370 1 None None None 74318296 Common - Prevent-host-death protein Tbd_2278 5 None None None 74317761 Common - Two Component Transcriptional Regulator, LuxR family Tbd_1743 216 COG4566 TtrR, Response regulator Signal transduction mechanisms 74318659 Common - partition protein A Tbd_2641 116 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 74318625 Nonpathogen - hypothetical protein Tbd_2607 2 None None None 74316153 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Tbd_0135 194 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74316257 Common - hypothetical protein Tbd_0239 39 None None None 74318452 Common - hypothetical protein Tbd_2434 11 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 74317397 Common - hypothetical protein Tbd_1379 12 None None None 74316641 Common - hypothetical protein Tbd_0623 29 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 74317081 Common - hypothetical protein Tbd_1063 15 None None None 74317108 Common - flagellar assembly protein FliH Tbd_1090 36 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 74317312 Common - type II secretion system protein F Tbd_1294 138 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 74317352 Common - Secretion protein HlyD Tbd_1334 161 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 74317393 Common - Ni-Fe hydrogenase large chain Tbd_1375 99 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 74317070 Nonpathogen - hypothetical protein Tbd_1052 7 None None None 74317180 Common - serine O-acetyltransferase Tbd_1162 210 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 74316038 Common trkA potassium transporter peripheral membrane component Tbd_0020 151 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 74317960 Common - Serine/Threonine protein kinase Tbd_1942 146 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 74316413 Common - Ribosomal protein L1 Tbd_0395 248 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 74317530 Common - tRNA isopentenyltransferase Tbd_1512 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 74317849 Common - ubiquinol-cytochrome c reductase cytochrome c1 subunit Tbd_1831 63 COG2857 CYT1, Cytochrome c1 Energy production and conversion 74316503 Common - hypothetical protein Tbd_0485 25 COG2128 COG2128, Uncharacterized conserved protein Function unknown 74316913 Nonpathogen - prevent-host-death protein Tbd_0895 1 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 74317491 Common - hypothetical protein Tbd_1473 78 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 74318703 Common - DEAD/DEAH box helicase Tbd_2685 126 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 74317498 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Tbd_1480 192 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74318821 Common - F0F1 ATP synthase subunit A Tbd_2803 201 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 74316435 Common rplE 50S ribosomal protein L5 Tbd_0417 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 74318727 Common - glutamyl-tRNA synthetase Tbd_2709 243 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 74317337 Common - hypothetical protein Tbd_1319 6 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 74318336 Common - hypothetical protein Tbd_2318 74 COG1238 COG1238, Predicted membrane protein Function unknown 74316617 Nonpathogen - hypothetical protein Tbd_0599 1 None None None 74316065 Common - glycolate oxidase, subunit GlcD Tbd_0047 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 74316260 Common folE GTP cyclohydrolase I Tbd_0242 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 74317701 Nonpathogen - hypothetical protein Tbd_1683 1 None None None 74317444 Common - putative arsenite transporter, ACR3 family Tbd_1426 124 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 74317767 Common - Two component Heavy metal response Transcriptional regulator, Winged helix family Tbd_1749 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74318751 Common - MFS permease Tbd_2733 50 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 74317967 Common - hypothetical protein Tbd_1949 41 COG4420 COG4420, Predicted membrane protein Function unknown 74318777 Common - glycosyl transferase, family 2 Tbd_2759 110 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 74317868 Common - ornithine carbamoyltransferase Tbd_1850 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 74317194 Common - flagellar biosynthetic protein FlhB Tbd_1176 37 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 74318393 Common - tRNA (guanine-N1-)-methyltransferase Tbd_2375 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 74317615 Common - hypothetical protein Tbd_1597 21 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 74317629 Common - flagellar biosynthesis protein FliQ Tbd_1611 96 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 74316673 Common - dehydrogenase complex, E1 component, alpha subunit Tbd_0655 159 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 74316551 Common - RNA polymerase factor sigma-54 Tbd_0533 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 74317516 Nonpathogen - hypothetical protein Tbd_1498 1 None None None 74318416 Common - hypothetical protein Tbd_2398 37 None None None 74318272 Common - hypothetical protein Tbd_2254 61 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 74316252 Common metH B12-dependent methionine synthase Tbd_0234 176 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 74317622 Common - flagellar protein FliJ Tbd_1604 19 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 74316097 Common - Transcriptional Regulator, Crp/Fnr family Tbd_0079 160 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 74317608 Common - flagellin FliC Tbd_1590 126 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 74316481 Common - 4-hydroxybenzoate polyprenyl transferase Tbd_0463 156 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 74316152 Nonpathogen - hypothetical protein Tbd_0134 1 None None None 74317410 Common - ABC transporter ATPase Tbd_1392 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 74316567 Common - putative Type II secretory pathway component PulD Tbd_0549 134 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 74317218 Common - putative oxidoreductase protein Tbd_1200 130 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 74317106 Common - flagellar biosynthesis/type III secretory pathway lipoprotein FliF Tbd_1088 121 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 74317328 Nonpathogen - hypothetical protein Tbd_1310 1 None None None 74316287 Common - Lipoate-protein ligase B Tbd_0269 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 74316758 Common - putative glycosyl transferase Tbd_0740 198 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74317671 Common - Predicted transmembrane transcriptional regulator (anti-sigma factor) Tbd_1653 25 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 74316383 Common - hypothetical protein Tbd_0365 29 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 74318376 Common - ferredoxin-NADP reductase Tbd_2358 101 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 74317905 Common - hypothetical protein Tbd_1887 6 None None None 74317921 Common - conserved hypothetical protein containing TPR repeat Tbd_1903 62 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 74318502 Common - sulfite reductase, dissimilatory-type beta subunit Tbd_2484 31 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 74317747 Common - hypothetical protein Tbd_1729 25 None None None 74318250 Common - membrane-bound lytic murein transglycosylase A Tbd_2232 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 74318836 Nonpathogen - hypothetical protein Tbd_2818 1 None None None 74316899 Common - exodeoxyribonuclease VII small subunit Tbd_0881 100 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 74317620 Common - flagellar assembly protein FliH Tbd_1602 60 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 74316469 Common - OsmC/Ohr family protein Tbd_0451 87 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 74318638 Common - hypothetical protein Tbd_2620 30 COG1872 COG1872, Uncharacterized conserved protein Function unknown 74316604 Common - alkyl hydroperoxide reductase Tbd_0586 224 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 74317798 Common - dTDP-glucose 4,6-dehydratase Tbd_1780 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 74318612 Common - fatty acid desaturase Tbd_2594 67 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 74317167 Common nuoH NADH dehydrogenase I chain H Tbd_1149 185 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 74318027 Common - probable integral membrane protein Tbd_2009 17 COG3235 COG3235, Predicted membrane protein Function unknown 74317785 Common - iron-containing alcohol dehydrogenase Tbd_1767 172 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 74318141 Common - 6-phosphogluconate dehydrogenase-like protein Tbd_2123 181 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 74317570 Common - fatty acid/phospholipid synthesis protein Tbd_1552 178 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 74318560 Common hslU ATP-dependent protease ATP-binding subunit Tbd_2542 213 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 74318803 Common - short chain dehydrogenase Tbd_2785 109 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 74318784 Common - hypothetical protein Tbd_2766 18 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 74317715 Common - putative terpenoid synthase Tbd_1697 112 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 74318306 Common phnP carbon-phosphorus lyase complex accessory protein Tbd_2288 81 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 74317482 Common - hypothetical protein Tbd_1464 29 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 74318509 Nonpathogen - hypothetical protein Tbd_2491 5 None None None 74316031 Common - peptidoglycan-binding LysM-like protein Tbd_0013 47 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 74318668 Common - carboxysome structural protein CsoS2 Tbd_2650 8 None None None 74318268 Common - hypothetical protein Tbd_2250 55 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 74318006 Common - phosphatidylserine decarboxylase Tbd_1988 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 74316429 Common rpsC 30S ribosomal protein S3 Tbd_0411 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 74317584 Nonpathogen - hypothetical protein Tbd_1566 4 None None None 74317253 Common - hypothetical protein Tbd_1235 105 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 74316217 Common - putative glycosyltransferase Tbd_0199 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 74318003 Common - integral membrane protein, DUF6 Tbd_1985 31 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 74317321 Common - hypothetical protein Tbd_1303 12 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74317590 Nonpathogen - hypothetical protein Tbd_1572 1 None None None 74317232 Nonpathogen - hypothetical protein Tbd_1214 1 None None None 74317814 Common - hypothetical protein Tbd_1796 12 None None None 74317204 Common - hypothetical protein Tbd_1186 28 COG2938 COG2938, Uncharacterized conserved protein Function unknown 74318344 Common - putative sulfite reductase Tbd_2326 55 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 74316834 Common - hypothetical protein Tbd_0816 18 COG4271 COG4271, Predicted nucleotide-binding protein containing TIR -like domain Transcription 74316803 Common - Ribosomal protein S2 Tbd_0785 228 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 74316021 Common gyrB DNA gyrase subunit B Tbd_0003 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 74317996 Nonpathogen - hypothetical protein Tbd_1978 4 None None None 74318365 Common - glycyl-tRNA synthetase, beta subunit Tbd_2347 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 74316274 Common - hypothetical protein Tbd_0256 7 None None None 74318525 Common - lipid A export ATP-binding/permease protein MsbA Tbd_2507 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 74318697 Nonpathogen - hypothetical protein Tbd_2679 3 None None None 74318241 Common - anthranilate phosphoribosyl transferase Tbd_2223 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 74316927 Common - putative TonB-dependent receptor Tbd_0909 121 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 74317316 Common - possible transmembrane protein Tbd_1298 9 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 74318734 Common cobD cobalamin biosynthesis protein Tbd_2716 154 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 74317888 Common - heptosyltransferase family protein Tbd_1870 109 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 74316659 Nonpathogen - cytochrome c oxidase, subunit CcoQ Tbd_0641 1 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 74318794 Common - putative transporter protein Tbd_2776 36 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 74317098 Common - hypothetical protein Tbd_1080 195 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74317929 Common - folylpolyglutamate synthetase Tbd_1911 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 74316634 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) Tbd_0616 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74318165 Common - hypothetical protein Tbd_2147 61 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 74317187 Common - ferredoxin, 2Fe-2S type Tbd_1169 99 COG0633 Fdx, Ferredoxin Energy production and conversion 74318567 Common - chemotaxis sensory transducer Tbd_2549 158 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 74317684 Common - peptidoglycan-binding protein LysM Tbd_1666 123 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 74316320 Common - glycosyltransferase Tbd_0302 218 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74318224 Common tolB translocation protein TolB Tbd_2206 163 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 74316907 Common - hypothetical protein Tbd_0889 33 COG4398 COG4398, Uncharacterized protein conserved in bacteria Function unknown 74316037 Common - Two Component Transcriptional Regulator, Fis family Tbd_0019 217 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 74317725 Common - phosphoribosyl-AMP cyclohydrolase Tbd_1707 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 74317433 Common - RND efflux system outer membrane lipoprotein NodT Tbd_1415 118 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 74317165 Common nuoF NADH-quinone oxidoreductase, chain F Tbd_1147 164 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 74317636 Common - chemotaxis sensory transducer Tbd_1618 161 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 74318191 Nonpathogen - hypothetical protein Tbd_2173 11 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 74317954 Common - hypothetical protein Tbd_1936 5 None None None 74318471 Common - DNA polymerase A Tbd_2453 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 74316695 Common - YbaK-like protein Tbd_0677 26 COG2606 EbsC, Uncharacterized conserved protein Function unknown 74318796 Nonpathogen - hypothetical protein Tbd_2778 1 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 74317125 Common - putative ferredoxin Tbd_1107 123 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 74317695 Common - peptidase S14, ClpP Tbd_1677 212 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 74318091 Common - putative integrase prophage protein Tbd_2073 103 COG0582 XerC, Integrase DNA replication, recombination, and repair 74318276 Common - putative glucose-fructose oxidoreductase oxidoreductase protein Tbd_2258 175 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 74316943 Common - adenine specific DNA methyltransferase Tbd_0925 32 COG4889 COG4889, Predicted helicase General function prediction only 74317601 Common - ABC transporter ATPase Tbd_1583 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 74317090 Common - conserved hypothetical protein containing twin-arginine translocation pathway signal Tbd_1072 71 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 74317545 Common - putative translation factor Sua5 Tbd_1527 234 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 74316972 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Tbd_0954 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 74316304 Common - UDP-N-acetylglucosamine 2-epimerase Tbd_0286 151 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 74317051 Common - probable collagenase Tbd_1033 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 74318459 Common - nicotinate-nucleotide adenylyltransferase Tbd_2441 180 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 74318322 Common - septum formation topological specificity factor MinE Tbd_2304 91 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 74316390 Nonpathogen - Conserved hypothetical protein 2293 Tbd_0372 2 COG5642 COG5642, Uncharacterized conserved protein Function unknown 74316375 Common - putative transport protein ExbB2 Tbd_0357 17 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 74317557 Common - molecular chaperone protein DnaJ Tbd_1539 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 74316518 Common - sodium/hydrogen exchanger family protein Tbd_0500 140 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 74317249 Nonpathogen - hypothetical protein Tbd_1231 1 None None None 74316194 Common - glycine dehydrogenase subunit 1 Tbd_0176 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 74318431 Common - HPrNtr Tbd_2413 159 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 74317477 Nonpathogen - hypothetical protein Tbd_1459 1 COG4831 COG4831, Uncharacterized conserved protein Function unknown 74316134 Common - Phospho-N-acetylmuramoyl-pentapeptide transferase Tbd_0116 218 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 74316892 Common - ATP-sulfurylase Tbd_0874 64 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 74316823 Common - succinyl-CoA synthase, beta subunit Tbd_0805 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 74318494 Nonpathogen - hypothetical protein Tbd_2476 15 None None None 74316531 Nonpathogen - hypothetical protein Tbd_0513 1 None None None 74318828 Common - ABC transporter ATPase Tbd_2810 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 74316733 Common - TonB-dependent siderophore receptor Tbd_0715 106 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 74318316 Common - ABC phosphonate permease Tbd_2298 129 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 74318047 Common - nuclease (SNase-like) Tbd_2029 38 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 74316881 Common - trans-hexaprenyltranstransferase Tbd_0863 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 74316950 Nonpathogen - hypothetical protein Tbd_0932 1 None None None 74317552 Common - putative glycosyltransferase Tbd_1534 41 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 74316397 Common - Conserved hypothetical protein 95 Tbd_0379 212 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 74318564 Common - hypothetical protein Tbd_2546 11 None None None 74316476 Common - peptidase family protein Tbd_0458 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 74317505 Nonpathogen - hypothetical protein Tbd_1487 1 None None None 74318661 Common - bacterioferritin Tbd_2643 101 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 74318109 Common - peptidase S1C, Do Tbd_2091 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 74318174 Common - hypothetical protein Tbd_2156 45 COG3439 COG3439, Uncharacterized conserved protein Function unknown 74316580 Common - nitric-oxide reductase subunit C Tbd_0562 37 COG2857 CYT1, Cytochrome c1 Energy production and conversion 74316937 Nonpathogen - hypothetical protein Tbd_0919 1 None None None 74318597 Common - hypothetical protein Tbd_2579 130 COG1678 COG1678, Putative transcriptional regulator Transcription 74317227 Nonpathogen - hypothetical protein Tbd_1209 1 None None None 74316209 Common - hypothetical protein Tbd_0191 80 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 74318687 Nonpathogen - hypothetical protein Tbd_2669 3 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 74317940 Common - isopropylmalate isomerase large subunit Tbd_1922 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 74318131 Common - hypothetical protein Tbd_2113 58 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 74316405 Common - ribose-phosphate pyrophosphokinase Tbd_0387 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 74316798 Common def peptide deformylase Tbd_0780 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 74316609 Common - hypothetical protein Tbd_0591 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 74316284 Common - serine-type D-ala-D-ala carboxypeptidase Tbd_0266 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 74317467 Nonpathogen - hypothetical protein Tbd_1449 2 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 74316969 Common - Chorismate mutase Tbd_0951 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 74316961 Common - putative integrase prophage protein Tbd_0943 102 COG0582 XerC, Integrase DNA replication, recombination, and repair 74316458 Common - hypothetical protein Tbd_0440 74 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 74318457 Common - hypothetical protein Tbd_2439 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 74316231 Common ubiB putative ubiquinone biosynthesis protein UbiB Tbd_0213 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 74317305 Common - Two component Transcriptional regulator, Winged helix family Tbd_1287 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74316846 Common - DNA polymerase III, alpha subunit Tbd_0828 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 74316715 Common infB translation initiation factor IF-2 Tbd_0697 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 74318303 Common - Possible Transcriptional Regulator, Fis family Tbd_2285 181 COG0583 LysR, Transcriptional regulator Transcription 74318485 Common - dihydroorotate dehydrogenase 2 Tbd_2467 33 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 74317129 Common - hypothetical protein Tbd_1111 12 None None None 74318065 Common - peptidyl-prolyl cis-trans isomerase Tbd_2047 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 74318238 Common - NADH dehydrogenase Tbd_2220 158 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 74316279 Common - Rod shape-determining protein MreC, subtype Tbd_0261 126 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 74316494 Common - Protein serine/threonine phosphatase Tbd_0476 129 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 74318450 Common - probable carbonic anhydrase, family 3 Tbd_2432 187 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 74316751 Common - hypothetical protein Tbd_0733 31 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 74318480 Common - probable transmembrane protein Tbd_2462 15 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 74317143 Common - dihydrodipicolinate reductase Tbd_1125 218 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 74316853 Common surE stationary phase survival protein SurE Tbd_0835 185 COG0496 SurE, Predicted acid phosphatase General function prediction only 74316155 Common - diheme cytochrome c Tbd_0137 17 None None None 74318261 Common - phospholipase D/Transphosphatidylase Tbd_2243 151 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 74316727 Common - putative signal peptide protein Tbd_0709 16 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 74316080 Common - hypothetical protein Tbd_0062 42 COG3651 COG3651, Uncharacterized protein conserved in bacteria Function unknown 74316512 Common - putative monovalent cation/H+ antiporter subunit E Tbd_0494 88 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 74318615 Common - long-chain fatty-acid-CoA ligase Tbd_2597 216 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 74316225 Common - shikimate kinase I Tbd_0207 198 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 74316577 Nonpathogen - hypothetical protein Tbd_0559 1 None None None 74318039 Common - Endonuclease III/Nth Tbd_2021 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 74316113 Common - metallo-beta-lactamase superfamily protein Tbd_0095 125 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 74317863 Common - putative protease Tbd_1845 182 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 74316543 Common - peptidase S16 Tbd_0525 64 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 74317548 Common - hypothetical protein Tbd_1530 71 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 74316259 Common - ammonium transporter Tbd_0241 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 74316365 Common - hypothetical protein Tbd_0347 36 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 74316537 Common - thioredoxin Tbd_0519 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 74316312 Common - glycosyl transferase, group 1 Tbd_0294 207 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74318721 Common - conserved hypothetical protein containing CBS domain Tbd_2703 218 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 74317526 Common - tetraacyldisaccharide-1-P 4'-kinase Tbd_1508 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 74317666 Nonpathogen - heterodisulfide reductase, subunit A Tbd_1648 37 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 74318383 Common - hypothetical protein Tbd_2365 68 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 74316124 Common - hypothetical protein Tbd_0106 64 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 74318693 Common - hypothetical protein Tbd_2675 103 COG0582 XerC, Integrase DNA replication, recombination, and repair 74317511 Common - hypothetical protein Tbd_1493 29 None None None 74317947 Common - hypothetical protein Tbd_1929 15 None None None 74318537 Common - S-adenosyl-L-homocysteine hydrolase Tbd_2519 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 74316093 Common - heme d1 biosynthesis protein NirF Tbd_0075 35 COG3391 COG3391, Uncharacterized conserved protein Function unknown 74316781 Nonpathogen - hypothetical protein Tbd_0763 1 None None None 74318424 Common - chemotaxis sensory transducer Tbd_2406 165 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 74318015 Nonpathogen - hypothetical protein Tbd_1997 1 None None None 74317963 Common - hypothetical protein Tbd_1945 215 COG2183 Tex, Transcriptional accessory protein Transcription 74318111 Common - Putative Sigma E regulatory protein, MucB/RseB Tbd_2093 49 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 74317842 Nonpathogen - hypothetical protein Tbd_1824 1 None None None 74316161 Common - heavy metal efflux pump CzcA Tbd_0143 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 74317201 Nonpathogen - succinate dehydrogenase, cytochrome b subunit Tbd_1183 1 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 74316498 Common - dienelactone hydrolase family protein Tbd_0480 107 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 74317563 Common - 4-amino-4-deoxychorismate lyase Tbd_1545 97 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 74317518 Common hppA membrane-bound proton-translocating pyrophosphatase Tbd_1500 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 74316589 Common - DMSO reductase chain B Tbd_0571 162 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 74317978 Common - hypothetical protein Tbd_1960 92 COG2353 COG2353, Uncharacterized conserved protein Function unknown 74316861 Common - homoserine dehydrogenase Tbd_0843 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 74316078 Common - asparagine synthase, glutamine-hydrolyzing Tbd_0060 183 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 74317821 Nonpathogen - hypothetical protein Tbd_1803 1 None None None 74317423 Common - nitrate reductase, delta subunit Tbd_1405 58 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 74317852 Common - putative protease Tbd_1834 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 74318707 Common - Periplasmic Sensor Signal Transduction Histidine Kinase Tbd_2689 157 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74316560 Common - hypothetical protein Tbd_0542 9 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74318110 Nonpathogen - putative positive regulator of sigma E activity Tbd_2092 1 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 74317138 Common - gamma-glutamyl kinase Tbd_1120 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 74318154 Common - hypothetical protein Tbd_2136 16 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 74316181 Common cbbA fructose-1,6-bisphosphate aldolase Tbd_0163 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 74316358 Nonpathogen - hypothetical protein Tbd_0340 2 None None None 74318252 Common - probable lipoprotein transmembrane Tbd_2234 8 COG5510 COG5510, Predicted small secreted protein Function unknown 74318346 Common - probable transcriptional regulator Tbd_2328 186 COG0583 LysR, Transcriptional regulator Transcription 74316172 Common - N-acetylglutamate synthase Tbd_0154 187 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 74317763 Nonpathogen - hypothetical protein Tbd_1745 12 None None None 74316220 Common - Type IV pilus assembly protein PilM Tbd_0202 82 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 74318019 Common - hypothetical protein Tbd_2001 4 None None None 74318646 Nonpathogen - hypothetical protein Tbd_2628 3 None None None 74318221 Common - radical activating enzyme; radical SAM family Tbd_2203 161 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 74318813 Common - outer membrane protein Tbd_2795 166 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 74317826 Common - site-specific recombinase, phage integrase family Tbd_1808 104 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 74318505 Common - hypothetical protein Tbd_2487 8 None None None 74317569 Common - 3-oxoacyl-(acyl carrier protein) synthase III Tbd_1551 203 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 74316776 Nonpathogen - hypothetical protein Tbd_0758 2 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 74317367 Nonpathogen - hypothetical protein Tbd_1349 1 None None None 74318122 Common - putative primosomal replication protein Tbd_2104 24 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 74316331 Common - rhamnosyl transferase related protein Tbd_0313 101 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 74318825 Common gidB glucose-inhibited division protein B Tbd_2807 205 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 74317913 Nonpathogen - NTP binding protein containing STAS domain Tbd_1895 1 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 74316430 Common rplP 50S ribosomal protein L16 Tbd_0412 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 74316392 Common - cell division protein FtsX Tbd_0374 85 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 74317028 Common rplT 50S ribosomal protein L20 Tbd_1010 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 74316263 Nonpathogen - hypothetical protein Tbd_0245 9 None None None 74316439 Common - ribosomal protein L18 Tbd_0421 92 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 74317332 Common - hypothetical protein Tbd_1314 4 None None None 74317293 Common - hypothetical protein Tbd_1275 45 COG2153 ElaA, Predicted acyltransferase General function prediction only 74316833 Common - ClpB protein Tbd_0815 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 74316173 Common - hypothetical protein Tbd_0155 195 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 74318497 Nonpathogen - putative DsrM protein Tbd_2479 20 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 74316308 Common - hypothetical protein Tbd_0290 31 None None None 74318519 Common - PAS/PAC Sensor Signal Transduction Histidine Kinase Tbd_2501 216 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 74317033 Common - superoxide dismutase, Fe Tbd_1015 206 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 74316146 Common - putative cytochrome C Tbd_0128 38 COG3258 COG3258, Cytochrome c Energy production and conversion 74318294 Common - adenine specific DNA methylase Tbd_2276 96 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 74316643 Common - UTP--glucose-1-phosphate uridylyltransferase Tbd_0625 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 74317074 Common - hypothetical protein Tbd_1056 41 COG2259 COG2259, Predicted membrane protein Function unknown 74316329 Common - hypothetical protein Tbd_0311 91 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 74317158 Common cbbJ triosephosphate isomerase Tbd_1140 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 74317487 Common - short-chain dehydrogenase/reductase Tbd_1469 227 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 74317395 Nonpathogen - hypothetical protein Tbd_1377 7 None None None 74317896 Common - ABC transporter permease protein Tbd_1878 74 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 74317354 Nonpathogen - hypothetical protein Tbd_1336 2 None None None 74317389 Common - conserved hypothetical protein containing TPR repeat Tbd_1371 26 None None None 74317983 Nonpathogen - hypothetical protein Tbd_1965 1 None None None 74318233 Common - hypothetical protein Tbd_2215 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 74316855 Common - peptidoglycan-binding protein LysM Tbd_0837 123 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 74317822 Nonpathogen - hypothetical protein Tbd_1804 2 None None None 74316058 Common - hypothetical protein Tbd_0040 129 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 74316791 Common - hypothetical protein Tbd_0773 7 None None None 74316529 Common - carbon-nitrogen hydrolase Tbd_0511 201 COG0388 COG0388, Predicted amidohydrolase General function prediction only 74317537 Common - N-acetylmuramoyl-L-alanine amidase Tbd_1519 178 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 74318403 Common rpsU 30S ribosomal protein S21 Tbd_2385 129 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 74317344 Common - hypothetical protein Tbd_1326 35 COG5569 COG5569, Uncharacterized conserved protein Function unknown 74316814 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Tbd_0796 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 74317042 Common - molybdopterin-guanine dinucleotide biosynthesis MobB Tbd_1024 89 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 74318045 Common - cytochrome c, class IC Tbd_2027 59 COG2863 COG2863, Cytochrome c553 Energy production and conversion 74317885 Common - hypothetical protein Tbd_1867 14 COG3660 COG3660, Predicted nucleoside-diphosphate-sugar epimerase Cell envelope biogenesis, outer membrane 74317289 Common - succinyl-diaminopimelate desuccinylase Tbd_1271 211 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 74316941 Common - hypothetical protein Tbd_0923 68 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 74318078 Common - glycosyl hydrolase family 57 Tbd_2060 34 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 74318159 Nonpathogen - hypothetical protein Tbd_2141 2 None None None 74318129 Common - spermidine synthase Tbd_2111 115 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 74317116 Common dapA dihydrodipicolinate synthase Tbd_1098 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 74317804 Common - hypothetical protein Tbd_1786 16 None None None 74317270 Common - peptidase S16, ATP-dependent protease La Tbd_1252 204 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 74316742 Nonpathogen - hypothetical protein Tbd_0724 1 None None None 74317635 Common - MCP methyltransferase, CheR-type Tbd_1617 150 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 74318607 Common rpmB 50S ribosomal protein L28 Tbd_2589 167 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 74316767 Common - hypothetical protein Tbd_0749 36 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 74318843 Common - preprotein translocase subunit YidC Tbd_2825 211 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 74317787 Nonpathogen - hypothetical protein Tbd_1769 7 None None None 74318102 Common recO DNA repair protein RecO Tbd_2084 62 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 74316703 Common - ABC transporter, ATPase protein Tbd_0685 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 74318198 Common - putative Long-chain fatty acid transport protein Tbd_2180 52 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 74316763 Common - hypothetical protein Tbd_0745 45 COG3569 COG3569, Topoisomerase IB DNA replication, recombination, and repair 74317658 Common - putative flagella synthesis protein FlgN Tbd_1640 8 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 74316524 Nonpathogen - hypothetical protein Tbd_0506 3 None None None 74316721 Common - hypothetical protein Tbd_0703 92 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 74316683 Common - transaldolase Tbd_0665 141 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 74317931 Common - tryptophan synthase, alpha chain Tbd_1913 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 74318187 Common - hypothetical protein Tbd_2169 41 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 74318061 Common aat leucyl/phenylalanyl-tRNA--protein transferase Tbd_2043 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 74318281 Nonpathogen - hypothetical protein Tbd_2263 1 None None None 74316451 Common - hydroxypyruvate reductase Tbd_0433 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 74318678 Common - hypothetical protein Tbd_2660 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 74317773 Common - hypothetical protein Tbd_1755 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 74316104 Nonpathogen - hypothetical protein Tbd_0086 1 None None None 74318189 Common - anaerobic ribonucleoside triphosphate reductase Tbd_2171 118 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 74317837 Nonpathogen - hypothetical protein Tbd_1819 1 None None None 74316318 Nonpathogen - hypothetical protein Tbd_0300 1 None None None 74318775 Common - sodium/hydrogen exchanger family protein Tbd_2757 80 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 74316586 Common - putative peptidase family M48 protein Tbd_0568 119 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 74317161 Common nuoB NADH dehydrogenase subunit B Tbd_1143 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 74317751 Common - DEAD/DEAH box helicase Tbd_1733 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 74316130 Common - Cell division protein FtsL Tbd_0112 21 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 74317907 Nonpathogen - hypothetical protein Tbd_1889 3 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 74317674 Common - transcription-repair coupling factor Tbd_1656 221 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 74316381 Common - hypothetical protein Tbd_0363 20 COG3339 COG3339, Uncharacterized conserved protein Function unknown 74317745 Common - hypothetical protein Tbd_1727 8 None None None 74318127 Nonpathogen - hypothetical protein Tbd_2109 1 None None None 74318140 Common - glucose-6-phosphate 1-dehydrogenase Tbd_2122 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 74318429 Common - putative thaimine biosynthesis protein Tbd_2411 134 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 74318558 Common - hypothetical protein Tbd_2540 12 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 74317146 Common - Carbamoyl-phosphate synthase, large subunit, glutamine-dependent Tbd_1128 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 74316558 Nonpathogen - hypothetical protein Tbd_0540 6 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 74317799 Common - glycosyltransferase, RfaG Tbd_1781 31 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74318610 Common - hypothetical protein Tbd_2592 9 COG3399 COG3399, Uncharacterized protein conserved in bacteria Function unknown 74317008 Common - ABC transporter, iron binding protein Tbd_0990 128 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 74317118 Common - hypothetical protein Tbd_1100 62 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 74317576 Common - probable transmembrane protein Tbd_1558 207 COG0313 COG0313, Predicted methyltransferases General function prediction only 74316484 Common - probable periplasmic C4-dicarboxylate binding protein DctP Tbd_0466 61 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 74316192 Common - thiol peroxidase-scavengase P20 oxidoreductase protein Tbd_0174 118 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 74316739 Common - hypothetical protein Tbd_0721 40 COG0439 AccC, Biotin carboxylase Lipid metabolism 74317280 Common - hypothetical protein Tbd_1262 50 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 74318801 Common - putative FtsN cell division protein Tbd_2783 31 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 74318008 Common - acetolactate synthase, small subunit Tbd_1990 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 74318695 Common - Possible Transcriptional Regulator Tbd_2677 37 COG3311 AlpA, Predicted transcriptional regulator Transcription 74317171 Common nuoL NADH dehydrogenase I chain L Tbd_1153 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 74317255 Common - ATP-dependent Clp protease, ATP-binding subunit Tbd_1237 221 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 74318147 Common - hypothetical protein Tbd_2129 21 None None None 74316929 Common - MotA/TolQ/ExbB proton channel family Tbd_0911 143 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 74316244 Common - diaminopimelate decarboxylase Tbd_0226 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 74317220 Common - twin-arginine translocation pathway signal Tbd_1202 41 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 74318666 Common - carboxysome protein A Tbd_2648 12 COG4576 CcmL, Carbon dioxide concentrating mechanism/carboxysome shell protein Secondary metabolites biosynthesis, transport, and catabolism / Energy production and conversion 74318503 Common - sulfite reductase, dissimilatory-type alpha subunit Tbd_2485 32 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 74316219 Common - peptidoglycan glycosyltransferase Tbd_0201 202 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 74316788 Common - hypothetical protein Tbd_0770 141 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 74316553 Common - OstA-like family protein Tbd_0535 67 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 74317500 Common - CDP-diacylglycerol-serine o-phosphatidyltransferase Tbd_1482 137 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 74316033 Common - methionyl-tRNA formyltransferase Tbd_0015 214 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 74318120 Common - ribosomal protein L9 Tbd_2102 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 74318490 Nonpathogen - hypothetical protein Tbd_2472 1 COG0316 IscA, Uncharacterized conserved protein Function unknown 74318024 Common - peroxiredoxin-like protein Tbd_2006 230 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 74317010 Common - hypothetical protein Tbd_0992 137 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 74317360 Common - hypothetical protein Tbd_1342 17 COG5642 COG5642, Uncharacterized conserved protein Function unknown 74316952 Common - hypothetical protein Tbd_0934 28 None None None 74316246 Common - Transcriptional Regulator, MarR family Tbd_0228 13 COG1846 MarR, Transcriptional regulators Transcription 74317532 Common - hypothetical protein Tbd_1514 11 None None None 74316885 Nonpathogen - hypothetical protein Tbd_0867 3 None None None 74316322 Nonpathogen - hypothetical protein containg TPR repeat Tbd_0304 1 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 74317210 Common - Response regulator receiver domain protein (CheY) Tbd_1192 176 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 74316501 Nonpathogen - hypothetical protein Tbd_0483 7 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 74318356 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Tbd_2338 163 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 74316619 Common - galactose-1-phosphate uridyl transferase, class I Tbd_0601 78 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 74316211 Nonpathogen - hypothetical protein Tbd_0193 1 None None None 74316723 Common - bacterioferritin-associated ferredoxin Tbd_0705 39 COG2906 Bfd, Bacterioferritin-associated ferredoxin Inorganic ion transport and metabolism 74318051 Common hemH ferrochelatase Tbd_2033 159 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 74317262 Common motB flagellar motor protein MotB Tbd_1244 107 COG1360 MotB, Flagellar motor protein Cell motility and secretion 74317847 Common - ClpXP protease specificity-enhancing factor Tbd_1829 64 COG2969 SspB, Stringent starvation protein B General function prediction only 74317965 Nonpathogen - hypothetical protein Tbd_1947 2 COG3889 COG3889, Predicted solute binding protein General function prediction only 74317998 Common - hypothetical protein Tbd_1980 19 COG3308 COG3308, Predicted membrane protein Function unknown 74318808 Common - thiol:disulfide interchange protein DsbD Tbd_2790 77 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 74317339 Common - hypothetical protein Tbd_1321 10 COG3391 COG3391, Uncharacterized conserved protein Function unknown 74317279 Common - hypothetical protein Tbd_1261 119 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 74316687 Common - glycine C-acetyltransferase Tbd_0669 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 74317269 Common - flagellar motor protein MotD Tbd_1251 151 COG1360 MotB, Flagellar motor protein Cell motility and secretion 74317417 Common - DNA-binding response regulator in two-component regulatory system with NarX (or NarQ) Tbd_1399 224 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 74317624 Common fliL flagellar basal body-associated protein FliL Tbd_1606 34 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 74316061 Common - hypothetical protein Tbd_0043 200 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 74318418 Common - glutaredoxin, GrxC Tbd_2400 113 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 74318248 Common cbbE ribulose-phosphate 3-epimerase Tbd_2230 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 74316427 Common rpsS 30S ribosomal protein S19 Tbd_0409 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 74318770 Common - hypothetical protein Tbd_2752 11 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 74317192 Common - Alpha amylase, catalytic subdomain Tbd_1174 158 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 74316921 Common - Multi-sensor Signal Transduction Histidine Kinase Tbd_0903 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 74317581 Common - pseudouridine synthase, RluD Tbd_1563 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 74317330 Common - glucosyltransferase MdoH Tbd_1312 55 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 74318531 Common - hypothetical protein Tbd_2513 4 None None None 74317812 Common - chain length determinant protein Tbd_1794 73 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 74316175 Common - hypothetical protein Tbd_0157 34 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 74318442 Common - N6-adenine-specific DNA methylase Tbd_2424 132 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 74316675 Common - carboxymuconolactone decarboxylase domain protein Tbd_0657 12 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 74317720 Common - Sec-independent periplasmic protein translocase Tbd_1702 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 74317489 Common - hypothetical protein Tbd_1471 141 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 74318270 Nonpathogen - hypothetical protein Tbd_2252 2 None None None 74318760 Common - hypothetical protein Tbd_2742 10 None None None 74316095 Common - nitrite reductase (NO-forming) Tbd_0077 20 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 74316254 Common - hypothetical protein Tbd_0236 82 COG1814 COG1814, Uncharacterized membrane protein Function unknown 74318411 Common - peptidase family M23 protein Tbd_2393 189 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 74318826 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Tbd_2808 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 74317302 Common - molybdate ABC transporter, permease protein Tbd_1284 221 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 74317479 Nonpathogen - hypothetical protein Tbd_1461 4 COG4831 COG4831, Uncharacterized conserved protein Function unknown 74318374 Common - putative outer membrane lipoprotein Tbd_2356 7 COG3134 COG3134, Predicted outer membrane lipoprotein Function unknown 74317308 Common - Two Component Transcriptional Regulator, LuxR family Tbd_1290 210 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 74318274 Common - superoxide dismutase Tbd_2256 204 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 74318737 Common - hypothetical protein Tbd_2719 7 None None None 74316883 Common rpmA 50S ribosomal protein L27 Tbd_0865 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 74317384 Common - Putative diguanylate cyclase/phosphodiesterase (GGDEF & EAL domains) with PAS/PAC sensor(s) Tbd_1366 180 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 74318226 Common - biopolymer transport protein ExbD/TolR Tbd_2208 132 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 74317083 Nonpathogen - hypothetical protein Tbd_1065 6 None None None 74317733 Common - hypothetical protein Tbd_1715 12 None None None 74317559 Common - type IV pilus assembly protein PilZ Tbd_1541 33 COG3215 PilZ, Tfp pilus assembly protein PilZ Cell motility and secretion / Intracellular trafficking and secretion 74318746 Common - hypothetical protein Tbd_2728 28 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 74316612 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Tbd_0594 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 74318581 Common - CDP-6-deoxy-delta-3,4-glucoseen reductase Tbd_2563 167 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 74316306 Common - hypothetical protein Tbd_0288 25 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 74317053 Nonpathogen - hypothetical protein Tbd_1035 5 None None None 74318648 Nonpathogen - hypothetical protein Tbd_2630 3 COG0398 COG0398, Uncharacterized conserved protein Function unknown 74318314 Nonpathogen - hypothetical protein Tbd_2296 6 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 74318216 Common - putative regulatory protein RecX Tbd_2198 84 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 74316376 Common - biopolymer transport protein, ExbD/TolR family Tbd_0358 143 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 74317064 Common - xopolyphosphatase Tbd_1046 170 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 74318202 Common - 6-pyruvoyl tetrahydrobiopterin synthase Tbd_2184 91 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 74316601 Common - hypothetical protein Tbd_0583 47 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 74318811 Common - glucosamine-fructose-6-phosphate aminotransferase, isomerising Tbd_2793 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 74318544 Common - diaminopimelate epimerase Tbd_2526 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 74317693 Common - peptidase S16, ATP-dependent protease La Tbd_1675 211 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 74318299 Nonpathogen - hypothetical protein Tbd_2281 2 None None None 74316663 Common - dihydroorotate dehydrogenase 2 Tbd_0645 235 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 74316516 Common - Transcriptional Regulator, Fis family Tbd_0498 173 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 74316437 Common - ribosomal protein S8 Tbd_0419 244 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 74318786 Common gltD glutamate synthase subunit beta Tbd_2768 213 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 74316533 Common - DNA polymerase subunits gamma and tau Tbd_0515 245 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 74318818 Common - F-type H+-transporting ATP synthase, delta (OSCP) subunit Tbd_2800 192 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 74316507 Common - hypothetical protein Tbd_0489 129 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 74317900 Common - hypothetical protein Tbd_1882 8 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 74316801 Common - PII uridylyl-transferase Tbd_0783 124 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 74318211 Common - thiamine-monophosphate kinase Tbd_2193 200 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 74318792 Nonpathogen - hypothetical protein Tbd_2774 1 None None None 74317455 Common - hypothetical protein Tbd_1437 8 None None None 74317230 Nonpathogen - hypothetical protein Tbd_1212 1 None None None 74318265 Common ligD ATP-dependent DNA ligase Tbd_2247 94 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 74318732 Common - cobyric acid synthase Tbd_2714 151 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 74318730 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Tbd_2712 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 74317404 Common - Hydrogenase expression/formation protein HypE Tbd_1386 117 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 74318329 Common - catalase Tbd_2311 125 COG0753 KatE, Catalase Inorganic ion transport and metabolism 74316346 Common - cytochrome C oxidase assembly protein Tbd_0328 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 74316681 Common - putative Mg(2+) transporter Tbd_0663 50 COG1285 SapB, Uncharacterized membrane protein Function unknown 74317956 Common - Putative diguanylate phosphodiesterase (EAL domain) Tbd_1938 79 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 74318799 Common - Primosomal protein n Tbd_2781 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 74316338 Common - 8-amino-7-oxononanoate synthase Tbd_0320 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 74317018 Common - hypothetical protein Tbd_1000 93 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 74317229 Nonpathogen - HNH nuclease Tbd_1211 2 None None None 74317472 Common - hypothetical protein Tbd_1454 9 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 74317873 Common - virulence factor MVIN-like protein Tbd_1855 187 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 74318685 Common - phosphoribosylformylglycinamidine cyclo-ligase Tbd_2667 226 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 74316821 Nonpathogen - hypothetical protein Tbd_0803 3 None None None 74317096 Common - heat shock protein 90 Tbd_1078 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 74317776 Common - GTP diphosphokinase, RelA/SpoT protein Tbd_1758 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 74316657 Common - probable iron-sulfur 4Fe-4S ferredoxin transmembrane protein Tbd_0639 79 COG0348 NapH, Polyferredoxin Energy production and conversion 74316057 Common rpmE 50S ribosomal protein L31 Tbd_0039 205 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 74317318 Common - type II secretion system protein D Tbd_1300 137 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 74316354 Common - hypothetical protein Tbd_0336 143 COG1959 COG1959, Predicted transcriptional regulator Transcription 74316986 Common - peptide chain release factor 3 Tbd_0968 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 74316500 Common - Possible Transcriptional Regulator, TetR family Tbd_0482 59 COG1309 AcrR, Transcriptional regulator Transcription 74318755 Common - hypothetical protein Tbd_2737 42 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 74318092 Common - queuosine biosynthesis protein Tbd_2074 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 74317682 Common - methyl-transferase Tbd_1664 80 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 74316654 Common - Putative diguanylate cyclase (GGDEF domain) Tbd_0636 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 74317886 Common - putative glycosyltransferase Tbd_1868 134 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 74318363 Common - phospholipid/glycerol acyltransferase Tbd_2345 180 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 74318578 Common - divalent cation tolerance protein Tbd_2560 91 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 74317727 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Tbd_1709 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 74316528 Common - Conserved hypothetical protein 2099 Tbd_0510 57 COG3164 COG3164, Predicted membrane protein Function unknown 74317894 Common - acetolactate synthase Tbd_1876 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 74318566 Common - CheA Signal Transduction Histidine Kinases (STHK) Tbd_2548 224 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 74318218 Nonpathogen - pilus assembly protein PilA Tbd_2200 2 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 74317435 Common - Hydrophobe/amphiphile efflux-1 HAE1 Tbd_1417 179 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 74316400 Common - hypothetical protein Tbd_0382 32 COG1160 COG1160, Predicted GTPases General function prediction only 74318243 Common - sulfide-quinone reductase Tbd_2225 87 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 74317541 Common - hypothetical protein Tbd_1523 111 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 74316068 Common - Transcriptional Regulator, IclR family Tbd_0050 122 COG1414 IclR, Transcriptional regulator Transcription 74316877 Common - putative acylphosphatase Tbd_0859 123 COG1254 AcyP, Acylphosphatases Energy production and conversion 74317603 Common - hypothetical protein Tbd_1585 100 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 74316693 Nonpathogen - hypothetical protein Tbd_0675 3 COG2327 WcaK, Uncharacterized conserved protein Function unknown 74316970 Common - histidinol-phosphate aminotransferase Tbd_0952 234 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 74317240 Common - integral membrane protein, DUF6 Tbd_1222 14 COG2962 RarD, Predicted permeases General function prediction only 74316808 Common - phosphatidate cytidylyltransferase Tbd_0790 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 74316023 Nonpathogen - hypothetical protein Tbd_0005 1 None None None 74316909 Common - aconitate hydratase 1 Tbd_0891 223 COG1048 AcnA, Aconitase A Energy production and conversion