Ralstonia eutropha JMP134 plasmid 1, complete sequence NC_007337 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 72384284 Common - Protein of unknown function DUF35 Reut_D6482 23 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 72384257 Common - RelB antitoxin Reut_D6453 26 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 72384310 Common - Conjugal transfer TrbH Reut_D6508 7 None None None 72384247 Common - hypothetical protein Reut_D6443 7 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 72384266 Common - Carboxymethylenebutenolidase Reut_D6464 91 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 72384270 Common - Transposase, IS4 Reut_D6468 37 None None None 72384250 Common - hypothetical protein Reut_D6446 3 None None None 72384279 Common - regulatory protein, IclR Reut_D6477 116 COG1414 IclR, Transcriptional regulator Transcription 72384264 Common - Monooxygenase, FAD-binding Reut_D6462 62 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 72384309 Common - Conjugal transfer protein TrbG/VirB9/CagX Reut_D6507 50 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 72384293 Common - Transposase Tn3 Reut_D6491 53 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 72384307 Common - CagE, TrbE, VirB component of type IV transporter system Reut_D6505 65 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 72384322 Common - hypothetical protein Reut_D6520 2 None None None 72384289 Common - Extracellular ligand-binding receptor Reut_D6487 148 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 72384259 Common - hypothetical protein Reut_D6455 38 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 72384245 Common - hypothetical protein Reut_D6441 3 None None None 72384316 Common - Lytic transglycosylase, catalytic Reut_D6514 22 None None None 72384268 Common - Catechol dioxygenase, N-terminal Reut_D6466 44 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 72384282 Common - acyl-CoA synthetase Reut_D6480 219 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 72384319 Common - hypothetical protein Reut_D6517 4 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 72384275 Common - Catechol dioxygenase, N-terminal Reut_D6473 46 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 72384277 Common - regulatory protein, LysR:LysR, substrate-binding Reut_D6475 167 COG0583 LysR, Transcriptional regulator Transcription 72384252 Common - hypothetical protein Reut_D6448 3 None None None 72384331 Common - transfer origin protein, TraL Reut_D6529 15 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 72384305 Common - Conjugal transfer protein TrbC Reut_D6503 14 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 72384287 Common - regulatory protein, TetR Reut_D6485 138 COG1309 AcrR, Transcriptional regulator Transcription 72384291 Common - inner-membrane translocator Reut_D6489 151 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 72384298 Common - Mercuric transport protein periplasmic component Reut_D6496 111 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 72384320 Common - phage DNA methylase Reut_D6518 14 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 72384280 Common - regulatory protein, LysR:LysR, substrate-binding Reut_D6478 167 COG0583 LysR, Transcriptional regulator Transcription 72384286 Common - regulatory protein, IclR Reut_D6484 37 COG1414 IclR, Transcriptional regulator Transcription 72384273 Common - Iron-containing alcohol dehydrogenase Reut_D6471 158 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 72384254 Common - hypothetical protein Reut_D6450 3 None None None 72384317 Common - hypothetical protein Reut_D6515 3 None None None 72384321 Common - resolvase Reut_D6519 64 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 72384326 Common - TraF protein of DNA transfer system Reut_D6524 22 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 72384300 Common - Hg(II)-responsive transcriptional regulator Reut_D6498 134 COG0789 SoxR, Predicted transcriptional regulators Transcription 72384262 Common - hypothetical protein Reut_D6458 2 None None None 72384256 Common - Antirestriction protein Reut_D6452 17 None None None 72384315 Common - TrbM Reut_D6513 8 None None None 72384312 Common - TrbJ protein of DNA transfer system Reut_D6510 14 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 72384249 Common - Cobyrinic acid a,c-diamide synthase Reut_D6445 175 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 72384269 Common - regulatory protein, LysR Reut_D6467 183 COG0583 LysR, Transcriptional regulator Transcription 72384295 Common - MerE Reut_D6493 10 None None None 72384258 Common - Plasmid stabilization system Reut_D6454 30 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 72384324 Common - conjugal transfer protein Reut_D6522 10 None None None 72384332 Common - TraM protein Reut_D6530 7 None None None 72384278 Common - Enoyl-CoA hydratase/isomerase Reut_D6476 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 72384304 Common - type II secretion system protein E Reut_D6502 224 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 72384292 Common - ABC transporter related Reut_D6490 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 72384299 Common - Mercuric transport protein MerT Reut_D6497 25 None None None 72384325 Common - DNA topoisomerase III Reut_D6523 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 72384311 Common - conjugation TrbI-like protein Reut_D6509 58 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 72384318 Common - TraX Reut_D6516 10 None None None 72384283 Common - Thiolase Reut_D6481 93 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 72384265 Common - Iron-containing alcohol dehydrogenase Reut_D6463 155 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 72384248 Common - ParB-like partition protein Reut_D6444 121 COG1475 Spo0J, Predicted transcriptional regulators Transcription 72384271 Common - Benzoate transport Reut_D6469 80 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 72384263 Common - hypothetical protein Reut_D6459 4 None None None 72384302 Common - Single-strand binding protein Reut_D6500 174 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 72384330 Common - TraK protein of DNA transfer system Reut_D6528 8 None None None 72384290 Common - inner-membrane translocator Reut_D6488 134 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 72384288 Common - Short-chain dehydrogenase/reductase SDR Reut_D6486 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 72384323 Common - TOPRIM Reut_D6521 67 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 72384297 Common - Mercuric reductase MerA Reut_D6495 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 72384246 Common - putative conjugation protein TraO Reut_D6442 4 None None None 72384328 Common - Relaxase/mobilization nuclease domain Reut_D6526 22 None None None 72384267 Common - Mandelate racemase/muconate lactonizing enzyme Reut_D6465 139 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 72384260 Common - phage integrase Reut_D6456 201 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 72384276 Common - Muconate cycloisomerase Reut_D6474 137 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 72384281 Common - Taurine catabolism dioxygenase TauD/TfdA Reut_D6479 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 72384251 Common - hypothetical protein Reut_D6447 4 None None None 72384329 Common - TraJ protein of DNA transfer system Reut_D6527 11 None None None 72384308 Common - Conjugal transfer protein Reut_D6506 33 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 72384301 Common - TrfA Reut_D6499 13 None None None 72384303 Common - Helix-turn-helix motif Reut_D6501 5 COG3655 COG3655, Predicted transcriptional regulator Transcription 72384274 Nonpathogen - Carboxymethylenebutenolidase Reut_D6472 1 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 72384327 Common - TRAG protein Reut_D6525 74 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 72384285 Common - Rieske (2Fe-2S) region Reut_D6483 74 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 72384253 Common - hypothetical protein Reut_D6449 5 None None None 72384314 Common - TrbL/VirB6 plasmid conjugal transfer protein Reut_D6512 23 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 72384294 Common - EAL Reut_D6492 148 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 72384306 Common - Conjugal transfer TrbD Reut_D6504 15 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 72384272 Common - Monooxygenase, FAD-binding Reut_D6470 77 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 72384261 Common - Transposase Tn3 Reut_D6457 50 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 72384313 Common - entry exclusion protein TrbK Reut_D6511 6 None None None 72384255 Nonpathogen - hypothetical protein Reut_D6451 2 None None None 72384296 Common - Mercuric resistence transcriptional repressor protein MerD Reut_D6494 10 COG0789 SoxR, Predicted transcriptional regulators Transcription