Rickettsia felis URRWXCal2, complete genome NC_007109 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 67458796 Pathogen - hypothetical protein RF_0404 1 None None None 67459045 Common rnd2 Ribonuclease D RF_0653 82 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 67459301 Common - hypothetical protein RF_0909 8 None None None 67458919 Common bioB Biotin synthase RF_0527 185 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 67459255 Common rluA2 Ribosomal large subunit pseudouridine synthase RF_0863 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 67459020 Common - hypothetical protein RF_0628 1 None None None 67458431 Common folKP Folate synthesis bifunctional protein RF_0039 219 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 67458809 Common aas acylglycerophosphoethanolamine acyltransferase RF_0417 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 67459764 Common - hypothetical protein RF_1372 8 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 67458476 Common rpmE 50S ribosomal protein L31 RF_0084 6 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 67459774 Common - hypothetical protein RF_1382 7 COG1434 COG1434, Uncharacterized conserved protein Function unknown 67459171 Common - Antitoxin of toxin-antitoxin system Phd RF_0779 4 None None None 67458987 Common mutT ADP-ribose pyrophosphatase MutT RF_0595 54 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 67458460 Common cysS cysteinyl-tRNA synthetase RF_0068 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67458695 Common rplQ 50S ribosomal protein L17 RF_0303 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 67459476 Common dnaK molecular chaperone DnaK RF_1084 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 67458670 Common rplC 50S ribosomal protein L3 RF_0278 224 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 162022121 Common ppa inorganic pyrophosphatase RF_0962 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 67458835 Common - hypothetical protein RF_0443 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 67459612 Common - hypothetical protein RF_1220 50 COG4804 COG4804, Uncharacterized conserved protein Function unknown 67459640 Common tatC Sec-independent protein translocase protein TatC RF_1248 201 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 67458398 Common lpxA UDP-N-acetylglucosamine acyltransferase RF_0006 164 COG1043 LpxA, Acyl- acyl carrier protein 67458465 Common - hypothetical protein RF_0073 39 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 67459481 Common recN DNA repair protein RecN RF_1089 218 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 67458760 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase RF_0368 209 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 67459719 Common - MFS type sugar transporter RF_1327 115 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67458461 Common rpsB 30S ribosomal protein S2 RF_0069 227 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 67459263 Common infB translation initiation factor IF-2 RF_0871 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 67459182 Common - hypothetical protein RF_0790 1 None None None 67458810 Common pccB Propionyl-CoA carboxylase beta chain precursor RF_0418 215 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 67458827 Common - Transposase RF_0435 70 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459328 Pathogen - hypothetical protein RF_0936 1 None None None 67458805 Common gltX glutamyl-tRNA synthetase RF_0413 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 67458472 Common - ABC transporter permease protein RF_0080 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 67459046 Common - hypothetical protein RF_0654 24 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 67458789 Common - MFS type sugar transporter RF_0397 3 None None None 67458942 Common cyoB protoheme IX farnesyltransferase RF_0550 167 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 67458737 Common - hypothetical protein RF_0345 1 None None None 67459636 Common dnaE DNA polymerase III subunit alpha RF_1244 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 67459588 Common tatA twin argininte translocase protein A RF_1196 2 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 67459650 Common nuoM NADH dehydrogenase subunit M RF_1258 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 67458957 Common nuoC NADH dehydrogenase subunit C RF_0565 172 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 67459518 Common pyrH uridylate kinase RF_1126 244 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 67458950 Common - hypothetical protein RF_0558 1 None None None 67459581 Common - Serine esterase RF_1189 74 COG0400 COG0400, Predicted esterase General function prediction only 67459243 Common - hypothetical protein RF_0851 1 COG5096 COG5096, Vesicle coat complex, various subunits Intracellular trafficking and secretion 67458713 Common - Transposase RF_0321 52 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458949 Common xseB exodeoxyribonuclease VII small subunit RF_0557 102 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 67459125 Common addA Erythrocyte adducin alpha subunit RF_0733 28 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 67458675 Common rplV 50S ribosomal protein L22 RF_0283 225 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 67458994 Common - Cytotoxic translational repressor of toxin-antitoxin system RelE RF_0602 1 None None None 67459205 Common - hypothetical protein RF_0813 1 None None None 67459109 Common abcT2 ABC transporter ATP-binding protein RF_0717 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 67459385 Common - WD40-like repeat RF_0993 83 COG1520 COG1520, FOG: WD40-like repeat Function unknown 67459017 Pathogen - hypothetical protein RF_0625 1 None None None 67458846 Common ptrB Protease II RF_0454 107 COG1770 PtrB, Protease II Amino acid transport and metabolism 67459753 Common pntA2 NAD(P) transhydrogenase subunit alpha RF_1361 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 67458972 Common - Ankyrin repeat RF_0580 65 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 162022117 Common nuoK NADH dehydrogenase subunit K RF_1256 163 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 67458635 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase RF_0243 214 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 67459245 Common - Predicted NTPase RF_0853 9 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 67459052 Common dapA dihydrodipicolinate synthase RF_0660 234 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 67458622 Common - Transposase RF_0230 31 COG5464 COG5464, Uncharacterized conserved protein Function unknown 67459466 Common - hypothetical protein RF_1074 12 None None None 67459434 Common - hypothetical protein RF_1042 3 None None None 67459698 Common - Ankyrin repeat RF_1306 36 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 67458902 Common aprE Alkaline protease secretion protein AprE RF_0510 133 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 67459525 Common dapB dihydrodipicolinate reductase RF_1133 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 67458449 Common queF 7-cyano-7-deazaguanine reductase RF_0057 81 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 67459621 Common gmk guanylate kinase RF_1229 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 67459706 Common - Putative outer surface protein RF_1314 10 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 67458973 Common dsbB Disulfide bond formation protein DsbB RF_0581 4 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 67459785 Common - Transposase RF_1393 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458631 Common - hypothetical protein RF_0239 1 None None None 67458702 Common - Tetratricopeptide repeat domain containing protein RF_0310 174 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 67459031 Common - RND family efflux transporter RF_0639 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 67458630 Common - Poly-beta-hydroxyalkanoate depolymerase RF_0238 46 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 67459450 Common - Excinuclease ABC, C subunit, N-terminal RF_1058 32 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 67458681 Common rplX 50S ribosomal protein L24 RF_0289 208 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 67458591 Pathogen - hypothetical protein RF_0199 1 None None None 67459215 Pathogen - hypothetical protein RF_0823 1 None None None 67458429 Common - Dihydrofolate reductase FolA RF_0037 4 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 67459029 Common - hypothetical protein RF_0637 1 None None None 67458768 Common - hypothetical protein RF_0376 1 None None None 67458522 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase RF_0130 205 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 67458617 Common - hypothetical protein RF_0225 95 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 67458780 Common - transposase/IS protein RF_0388 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 67458723 Common abcT3 Multidrug resistance ABC transporter ATP-binding protein RF_0331 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 67458500 Common - hypothetical protein RF_0108 2 None None None 67459366 Pathogen - hypothetical protein RF_0974 1 None None None 67459110 Common - hypothetical protein RF_0718 1 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 67458880 Common - Predicted metal-dependent hydrolase RF_0488 142 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 67459141 Common - Phage prohead protease (HK97 family) and phage major capsid protein (HK97 family) RF_0749 50 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 67459311 Common - Type I site-specific restriction-modification system, R (restriction) subunit RF_0919 124 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 67458817 Common - hypothetical protein RF_0425 25 COG5590 COG5590, Uncharacterized conserved protein Function unknown 67458879 Common nlpD1 Membrane proteins related to metalloendopeptidase RF_0487 28 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 67458751 Common - Site-specific recombinases RF_0359 37 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 67458683 Common rpsN 30S ribosomal protein S14 RF_0291 199 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 67459380 Common parE DNA topoisomerase IV subunit B RF_0988 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 67458721 Common - Nucleotidyltransferase domain RF_0329 31 None None None 67458659 Common - NifU-like domain RF_0267 85 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 67458745 Common pth peptidyl-tRNA hydrolase RF_0353 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 67458845 Common rodA Rod shape-determining protein RodA RF_0453 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 67458756 Common dnaA chromosomal replication initiation protein RF_0364 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 67458446 Common dcd deoxycytidine triphosphate deaminase RF_0054 149 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 67459061 Common rbfA ribosome-binding factor A RF_0669 64 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 67459568 Common rnc ribonuclease III RF_1176 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 67459065 Common - hypothetical protein RF_0673 1 None None None 67459095 Common - hypothetical protein RF_0703 15 COG5430 COG5430, Uncharacterized secreted protein Function unknown 67459571 Common secF preprotein translocase subunit SecF RF_1179 215 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 67458562 Common - hypothetical protein RF_0170 1 None None None 67459112 Common kpsF KpsF protein RF_0720 179 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 67458775 Common - Transposase RF_0383 54 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459765 Common dinJ DNA-damage-inducible protein J RF_1373 35 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 67458413 Common - ComEC/Rec2-related protein RF_0021 12 None None None 67458986 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase RF_0594 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 67459460 Common sca8 Cell surface antigen-like protein Sca8 RF_1068 5 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 67458581 Common - hypothetical protein RF_0189 1 None None None 67458532 Common tilS tRNA(Ile)-lysidine synthetase TilS RF_0140 187 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 67458728 Common cydB Cytochrome d ubiquinol oxidase subunit II RF_0336 150 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 67458530 Common - Site-specific DNA methylase RF_0138 63 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 67459415 Common rluA1 Ribosomal large subunit pseudouridine synthase RF_1023 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 67458866 Common - Cell surface antigen-like protein Sca7 RF_0474 60 None None None 67459646 Common - hypothetical protein RF_1254 45 COG4797 COG4797, Predicted regulatory domain of a methyltransferase General function prediction only 67459297 Common mraZ hypothetical protein RF_0905 122 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 67459322 Common - Transposase RF_0930 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458652 Common - TPR repeats RF_0260 140 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 67459001 Common dacF Penicillin-binding protein DacF precursor RF_0609 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 67459577 Common tlyC Hemolysin C RF_1185 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 67459606 Common trmE tRNA modification GTPase TrmE RF_1214 219 COG0486 ThdF, Predicted GTPase General function prediction only 67458620 Common - hypothetical protein RF_0228 17 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 67459329 Common - hypothetical protein RF_0937 1 None None None 67458643 Common - Predicted membrane protein RF_0251 13 COG2860 COG2860, Predicted membrane protein Function unknown 67459398 Common - hypothetical protein RF_1006 6 None None None 67459530 Common aspS aspartyl-tRNA synthetase RF_1138 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67458940 Pathogen - ABC transporter, ATP-binding protein RF_0548 1 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 67459371 Common thrS threonyl-tRNA synthetase RF_0979 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67459559 Common hflC2 Membrane protease subunits RF_1167 216 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 67459196 Common - hypothetical protein RF_0804 1 None None None 67459165 Common - Bacterial transcription activator, effector binding domain RF_0773 20 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 67458820 Common - Acetyltransferase RF_0428 23 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 67459213 Pathogen - hypothetical protein RF_0821 3 None None None 67458762 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase RF_0370 213 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 67459732 Common - Uracil-DNA glycosylase, family 4 RF_1340 152 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 67459780 Common - hypothetical protein RF_1388 2 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 67459235 Common iscA2 Iron-sulfur cluster assembly accessory protein RF_0843 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 67458856 Common - hypothetical protein RF_0464 1 None None None 67459221 Common - hypothetical protein RF_0829 2 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 67459079 Common uvrD DNA helicase II RF_0687 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 67459161 Common - hypothetical protein RF_0769 82 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 67458735 Common - Transposase RF_0343 42 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459155 Common recJ Single-stranded-DNA-specific exonuclease RecJ RF_0763 194 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 67459508 Pathogen - hypothetical protein RF_1116 1 None None None 67459610 Common - hypothetical protein RF_1218 27 None None None 67459202 Common - hypothetical protein RF_0810 17 COG1723 COG1723, Uncharacterized conserved protein Function unknown 67458497 Common - Transposase RF_0105 52 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458455 Common - Ankyrin repeat RF_0063 1 None None None 67459351 Common secD preprotein translocase subunit SecD RF_0959 221 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 67459358 Common - Transposase RF_0966 21 None None None 67459228 Common rfaJ Lipopolysaccharide 1,2-glucosyltransferase RfaJ RF_0836 33 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 67459561 Common mrp Mrp protein RF_1169 236 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 67459315 Common - Ankyrin repeat RF_0923 8 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 67458496 Common secG preprotein translocase subunit SecG RF_0104 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 67459759 Common ampC Beta-lactamase AmpC (Class C) RF_1367 64 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 67459776 Common ampD AmpD protein homolog RF_1384 104 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 67459406 Common - putative monovalent cation/H+ antiporter subunit G RF_1014 4 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 67459070 Common - hypothetical protein RF_0678 1 None None None 162022123 Common rpsD 30S ribosomal protein S4 RF_0549 224 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 67459435 Common - hypothetical protein RF_1043 17 None None None 67459752 Common greA transcription elongation factor GreA RF_1360 204 COG0782 GreA, Transcription elongation factor Transcription 67458896 Common tolQ TolQ protein RF_0504 152 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 67458955 Common nuoE NADH dehydrogenase subunit E RF_0563 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 67458663 Common - Toxin of toxin-antitoxin system RF_0271 10 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 67459669 Common - Predicted ATPase RF_1277 57 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 67458886 Common cox11 cytochrome C oxidase assembly protein RF_0494 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 67459011 Common sppA1 Signal peptide peptidase SppA RF_0619 165 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 67459672 Common - NT (nucleotidyltransferase) domain and HEPN (higher eukarytoes and prokaryotes nucleotide-binding) domain RF_1280 9 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 67458458 Common - hypothetical protein RF_0066 49 COG1738 COG1738, Uncharacterized conserved protein Function unknown 67459369 Common - transposase/IS protein RF_0977 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 67458438 Pathogen - Cell surface antigen-like protein Sca10 RF_0046 1 None None None 67459340 Common - HAD-superfamily subfamily IIA hydrolase RF_0948 43 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 67458485 Common virB6_5 TrbL/VirB6 plasmid Conjugative transfer protein RF_0093 7 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 67459617 Common uup ABC transporter ATP-binding protein Uup RF_1225 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 67458569 Common coaE dephospho-CoA kinase RF_0177 140 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 67459469 Common coq7 Ubiquinone biosynthesis protein Coq7 RF_1077 45 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 67459058 Common - hypothetical protein RF_0666 2 COG3038 CybB, Cytochrome B561 Energy production and conversion 67458546 Common - hypothetical protein RF_0154 1 None None None 67458406 Pathogen - hypothetical protein RF_0014 1 None None None 67459006 Common - FTR1 family protein RF_0614 32 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 67459421 Common - hypothetical protein RF_1029 1 None None None 67459552 Common - hypothetical protein RF_1160 1 None None None 67459496 Common - Prolyl endopeptidase precursor RF_1104 96 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 67458640 Common engA GTP-binding protein EngA RF_0248 232 COG1160 COG1160, Predicted GTPases General function prediction only 67458718 Common - hypothetical protein RF_0326 38 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 67459247 Common - hypothetical protein RF_0855 4 None None None 67459211 Common - hypothetical protein RF_0819 1 None None None 67458690 Common secY preprotein translocase subunit SecY RF_0298 242 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 67458564 Common - hypothetical protein RF_0172 1 None None None 67458910 Common - Mg chelatase-related protein RF_0518 192 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 67458997 Common - hypothetical protein RF_0605 1 None None None 67459105 Common - hypothetical protein RF_0713 1 None None None 67458975 Common - Predicted permease RF_0583 87 COG0679 COG0679, Predicted permeases General function prediction only 67459055 Common - hypothetical protein RF_0663 1 None None None 67459381 Common ctp Carboxyl-terminal protease RF_0989 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 67459261 Common - Putative glycoprotein endopeptidase RF_0869 161 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 67459083 Common tdcB threonine dehydratase RF_0691 222 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 67459523 Common yqiX Amino acid ABC transporter substrate binding protein RF_1131 145 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 67458513 Common uhpC Sugar phosphate permease RF_0121 154 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 67459326 Pathogen - hypothetical protein RF_0934 1 None None None 67458470 Common prs Ribose-phosphate pyrophosphokinase RF_0078 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 67459729 Common obgE GTPase ObgE RF_1337 249 COG0536 Obg, Predicted GTPase General function prediction only 67459402 Common petA Ubiquinol-cytochrome c reductase, iron-sulfur subunit RF_1010 108 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 67459048 Common uppS Undecaprenyl pyrophosphate synthetase RF_0656 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 67458838 Common - hypothetical protein RF_0446 14 COG3832 COG3832, Uncharacterized conserved protein Function unknown 67458833 Common - MFS type sugar transporter RF_0441 124 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67459218 Common - hypothetical protein RF_0826 4 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 67459089 Common yhbH Probable sigma(54) modulation protein RF_0697 89 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 67459308 Common dat Methylated-DNA--protein-cysteine methyltransferase RF_0916 207 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 67458394 Common trxA Thioredoxin RF_0002 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 67459180 Common - Antitoxin of toxin-antitoxin system Phd RF_0788 10 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 67459488 Common gltP Na+/H+-dicarboxylate symporters RF_1096 159 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 67459738 Common glyS glycyl-tRNA synthetase subunit beta RF_1346 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 67458697 Common spoT5 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0305 203 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67458794 Common grpE GrpE protein RF_0402 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 67459445 Common - Transposase RF_1053 52 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459728 Common tig trigger factor RF_1336 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 67458474 Common - hypothetical protein RF_0082 1 None None None 67458917 Common - hypothetical protein RF_0525 12 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 67459782 Common - Oxidoreductase RF_1390 199 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 67459257 Common - N6-adenine-specific methylase RF_0865 194 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 67458711 Common sca11 Cell surface antigen-like protein Sca11 RF_0319 5 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 67459189 Pathogen - hypothetical protein RF_0797 1 None None None 67459519 Common frr ribosome recycling factor RF_1127 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 67458700 Common - Transposase RF_0308 69 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458409 Common - hypothetical protein RF_0017 195 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 67459711 Common - Cytosine deaminase RF_1319 207 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 67459478 Common chaB Cation transport regulator ChaB RF_1086 21 COG4572 ChaB, Putative cation transport regulator General function prediction only 67459675 Common kefB Glutathione-regulated potassium-efflux system protein KefB RF_1283 179 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 67458480 Common virB4_1 Type IV secretion/conjugal transfer ATPase, VirB4 family RF_0088 67 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 67458542 Common - ClpB protein RF_0150 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 67459744 Common - hypothetical protein RF_1352 2 None None None 67459283 Common comF Competence protein F RF_0891 32 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 67458559 Pathogen - hypothetical protein RF_0167 1 None None None 67459787 Common proP7 Proline/betaine transporter RF_1395 124 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67459703 Common mraY2 Undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase RF_1311 159 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 67459623 Common mreC Rod shape-determining protein MreC RF_1231 156 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 67458947 Common rimM 16S rRNA-processing protein RF_0555 135 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 67458901 Common proP2 Proline/betaine transporter RF_0509 122 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 67459033 Common - RND family efflux transporter RF_0641 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 67458926 Common - hypothetical protein RF_0534 70 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 67459117 Common sca4 Cell surface antigen RF_0725 8 None None None 67458848 Common vapC1 Toxin of toxin-antitoxin system VapC RF_0456 30 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 67458598 Common - hypothetical protein RF_0206 5 None None None 67459539 Common rplL 50S ribosomal protein L7/L12 RF_1147 213 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 67458633 Common manC Mannose-1-phosphate guanylyltransferase RF_0241 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 67458782 Common - Transposase RF_0390 69 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458608 Common - hypothetical protein RF_0216 16 COG1598 COG1598, Uncharacterized conserved protein Function unknown 67459627 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III RF_1235 219 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 67459730 Common gltA type II citrate synthase RF_1338 193 COG0372 GltA, Citrate synthase Energy production and conversion 67458996 Common ruvA Holliday junction DNA helicase motor protein RF_0604 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 67458885 Common rpoH RNA polymerase factor sigma-32 RF_0493 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 67458520 Common - hypothetical protein RF_0128 2 None None None 67458978 Common proP3 Proline/betaine transporter RF_0586 113 None None None 67459143 Common - hypothetical protein RF_0751 1 None None None 67458529 Common - Site-specific DNA methylase RF_0137 10 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 67459027 Common ftsW Cell division protein FtsW RF_0635 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 67458815 Common ileS isoleucyl-tRNA synthetase RF_0423 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67459368 Common - Transposase RF_0976 42 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458573 Common - hypothetical protein RF_0181 35 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 67459558 Common htrA Periplasmic serine protease RF_1166 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 67459686 Common dksA DnaK suppressor protein homolog RF_1294 155 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 67458615 Common - hypothetical protein RF_0223 3 None None None 67459136 Common birA biotin--protein ligase RF_0744 205 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 67458623 Common ubiA prenyltransferase RF_0231 160 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 67459544 Common secE preprotein translocase subunit SecE RF_1152 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 67459277 Common proP8 Proline/betaine transporter RF_0885 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67459173 Common - hypothetical protein RF_0781 1 None None None 67459713 Common omp 17 kDa surface antigen precursor RF_1321 26 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 67459652 Common nuoI NADH dehydrogenase subunit I RF_1260 194 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 67459207 Common - Na+/proline symporter and signal transduction histidine kinase RF_0815 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 67458908 Common hslU ATP-dependent protease ATP-binding subunit RF_0516 211 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 67459387 Common rpsI 30S ribosomal protein S9 RF_0995 218 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 67459503 Common - hypothetical protein RF_1111 154 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 67459107 Pathogen - hypothetical protein RF_0715 1 None None None 67459233 Common potE Putrescine-ornithine antiporter RF_0841 183 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 67459457 Common - hypothetical protein RF_1065 1 None None None 67459120 Common glnA Glutamine synthetase RF_0728 217 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 67459127 Common ppdK pyruvate phosphate dikinase RF_0735 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 67459709 Common - hypothetical protein RF_1317 41 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 67458550 Common - Transposase RF_0158 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459512 Common - Membrane-associated zinc metalloprotease RF_1120 210 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 67458841 Common - hypothetical protein RF_0449 1 None None None 67458637 Pathogen - hypothetical protein RF_0245 1 None None None 67458502 Common dgt deoxyguanosinetriphosphate triphosphohydrolase-like protein RF_0110 161 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 67458650 Common - hypothetical protein RF_0258 1 None None None 67458861 Common virD4 VirD4 protein RF_0469 73 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 67458422 Common atpB F0F1 ATP synthase subunit A RF_0030 207 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 67459003 Common rlpA Rare lipoprotein A precursor RF_0611 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 67459345 Common spoT3 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0953 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67459437 Common pssA CDP-diacylglycerol--serine O-phosphatidyltransferase RF_1045 139 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 67458888 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase RF_0496 216 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 67459119 Common rbn Ribonuclease BN, putative RF_0727 129 COG1295 Rbn, Predicted membrane protein Function unknown 67458813 Common - hypothetical protein RF_0421 20 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 67458544 Pathogen - hypothetical protein RF_0152 1 None None None 67458875 Common mutS DNA mismatch repair protein RF_0483 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 67459198 Common bioC Biotin synthesis protein BioC RF_0806 61 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 67459757 Common - hypothetical protein RF_1365 158 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 67458649 Common - hypothetical protein RF_0257 1 None None None 67459223 Common - hypothetical protein RF_0831 1 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 67458743 Common nrdG Organic radical activating enzyme RF_0351 172 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 67459665 Common - hypothetical protein RF_1273 3 None None None 67459417 Common rne Ribonuclease E RF_1025 184 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 67458863 Common - Phage portal protein RF_0471 65 COG4695 COG4695, Phage-related protein Function unknown 67458945 Common asmA Outer membrane assembly protein RF_0553 72 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 67458628 Common tatD Putative deoxyribonuclease, hydrolase RF_0236 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 67458825 Common corA Magnesium and cobalt transport protein CorA RF_0433 167 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 67458758 Common - hypothetical protein RF_0366 26 COG2938 COG2938, Uncharacterized conserved protein Function unknown 67458685 Common rplF 50S ribosomal protein L6 RF_0293 245 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 67459391 Common - Transposase RF_0999 53 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458654 Common cspA Cold shock-like protein RF_0262 173 COG1278 CspC, Cold shock proteins Transcription 67459270 Pathogen - hypothetical protein RF_0878 1 None None None 67458855 Common virB8_1 VirB8 protein RF_0463 5 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 67459493 Common - Transposase RF_1101 2 None None None 67459063 Common - hypothetical protein RF_0671 23 COG1714 COG1714, Predicted membrane protein/domain Function unknown 67458784 Common - Transposase RF_0392 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459573 Common - Transposase RF_1181 52 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458965 Common - hypothetical protein RF_0573 1 None None None 67459767 Common - DNA polymerase III subunit chi RF_1375 17 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 67458527 Common - hypothetical protein RF_0135 36 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 67458868 Common - Cell surface antigen-like protein Sca7 RF_0476 107 None None None 67459318 Common - Transposase RF_0926 53 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459187 Pathogen - rRNA methylase RF_0795 1 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 67459604 Common - hypothetical protein RF_1212 29 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 67459299 Common - hypothetical protein RF_0907 37 COG3177 COG3177, Uncharacterized conserved protein Function unknown 67459750 Common dnaG DNA primase RF_1358 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 67458619 Common - hypothetical protein RF_0227 17 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 67459338 Common - Excinuclease ABC, C subunit, N-terminal RF_0946 33 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 67458408 Common - Probable toxin of toxin-antitoxin system RF_0016 1 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 67459471 Common - hypothetical protein RF_1079 1 None None None 67458989 Common - Alkylated DNA repair protein RF_0597 6 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 67458733 Common - Integrase-like protein RF_0341 6 None None None 67458928 Common - Plasmid maintenance system antidote protein RF_0536 52 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 67459008 Common - hypothetical protein RF_0616 2 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 67459749 Common rpoD RNA polymerase sigma factor RpoD RF_1357 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 67458968 Common lnt apolipoprotein N-acyltransferase RF_0576 164 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 67458557 Common - Superfamily I DNA and RNA helicase RF_0165 40 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 67459742 Common - hypothetical protein RF_1350 2 None None None 67458484 Common virB6_4 TrbL/VirB6 plasmid Conjugative transfer protein RF_0092 22 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 67459250 Common priA primosome assembly protein PriA RF_0858 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 67458588 Common lpxK tetraacyldisaccharide 4'-kinase RF_0196 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 67459018 Common - Predicted glutamine amidotransferase RF_0626 126 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 67459013 Common mltE1 Soluble lytic murein transglycosylase precursor RF_0621 146 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 67459335 Common acpS 4'-phosphopantetheinyl transferase RF_0943 149 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 67459087 Pathogen - hypothetical protein RF_0695 1 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 67459667 Common blaD Beta-lactamase Class D RF_1275 37 COG2602 COG2602, Beta-lactamase class D Defense mechanisms 67459057 Common sucC succinyl-CoA synthetase subunit beta RF_0665 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 67458877 Common - hypothetical protein RF_0485 74 COG3177 COG3177, Uncharacterized conserved protein Function unknown 67458539 Pathogen - hypothetical protein RF_0147 1 None None None 67459355 Common mviN Integral membrane protein MviN RF_0963 191 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 67459400 Common - Endo/excinuclease amino terminal domain protein RF_1008 33 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 67459777 Common rpsP 30S ribosomal protein S16 RF_1385 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 67459501 Common acrF Hydrophobe/amphiphile efflux-1 HAE1 family protein RF_1109 180 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 67459163 Common rpsA 30S ribosomal protein S1 RF_0771 215 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 67458494 Common - Transposase RF_0102 43 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458953 Common - hypothetical protein RF_0561 42 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 67459593 Common - hypothetical protein RF_1201 1 None None None 67458931 Common capD CapD protein RF_0539 168 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 67459191 Common - hypothetical protein RF_0799 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 67459583 Common nth Endonuclease III RF_1191 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 67459134 Common - Predicted esterase of the alpha-beta hydrolase superfamily RF_0742 11 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 67459758 Common - hypothetical protein RF_1366 43 COG3577 COG3577, Predicted aspartyl protease General function prediction only 67458679 Common rpsQ 30S ribosomal protein S17 RF_0287 231 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 67458614 Common - hypothetical protein RF_0222 1 None None None 67459688 Common - Phasin family protein RF_1296 4 None None None 67459075 Common - hypothetical protein RF_0683 2 None None None 67459715 Common znuC Zinc ABC transporter ATP-binding protein RF_1323 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 67459784 Common - Transposase RF_1392 52 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459631 Common polA DNA polymerase I RF_1239 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 67459443 Common nudH dinucleoside polyphosphate hydrolase RF_1051 112 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 67459695 Pathogen - hypothetical protein RF_1303 1 None None None 67459231 Common ispB Octaprenyl-diphosphate synthase RF_0839 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 67459145 Common - Nucleotidyltransferase substrate binding protein RF_0753 28 None None None 67458726 Common - hypothetical protein RF_0334 34 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 67459092 Common trxB2 Thioredoxin reductase RF_0700 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 67459209 Common hemC porphobilinogen deaminase RF_0817 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 67459012 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase RF_0620 183 COG0756 Dut, dUTPase Nucleotide transport and metabolism 67458595 Common - Beta-glucosidase RF_0203 173 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 67458954 Common - hypothetical protein RF_0562 188 COG0759 COG0759, Uncharacterized conserved protein Function unknown 67459565 Common ruvC Holliday junction resolvase RF_1173 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 67459638 Common - hypothetical protein RF_1246 15 COG3164 COG3164, Predicted membrane protein Function unknown 67459238 Common spl1 Nifs protein homolog RF_0846 230 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 67458909 Common - hypothetical protein RF_0517 1 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 67459514 Common - hypothetical protein RF_1122 1 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 67459140 Common - hypothetical protein RF_0748 1 None None None 67459287 Common ntrX Nitrogen assimilation regulatory protein NtrX RF_0895 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 67458479 Common virB3 Type IV secretory pathway, VirB3-like protein RF_0087 17 COG3702 VirB3, Type IV secretory pathway, VirB3 components Intracellular trafficking and secretion 67459733 Common - Ribosomal large subunit pseudouridine synthase, RluD subfamily RF_1341 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 67459492 Common hemN coproporphyrinogen III oxidase RF_1100 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 67459249 Common - hypothetical protein RF_0857 1 None None None 67458505 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase RF_0113 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 67459099 Common - hypothetical protein RF_0707 13 COG5430 COG5430, Uncharacterized secreted protein Function unknown 67459700 Common fic Fic RF_1308 94 COG3177 COG3177, Uncharacterized conserved protein Function unknown 67459455 Common hscA chaperone protein HscA RF_1063 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 67459081 Common - hypothetical protein RF_0689 1 None None None 67459200 Common - 5-Formyltetrahydrofolate cyclo-ligase RF_0808 41 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 67459272 Common - Transposase RF_0880 52 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459555 Common sdhC Succinate dehydrogenase cytochrome b-556 subunit RF_1163 87 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 67458425 Common - Transcriptional regulator RF_0033 83 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 67459485 Common sucB dihydrolipoamide acetyltransferase RF_1093 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 67459025 Common - hypothetical protein RF_0633 1 None None None 67458946 Common - Transposase RF_0554 31 COG5464 COG5464, Uncharacterized conserved protein Function unknown 67458576 Common - hypothetical protein RF_0184 1 None None None 67458883 Common thyX FAD-dependent thymidylate synthase RF_0491 33 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 67458764 Common - Tryptophan repressor binding protein RF_0372 106 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 67459425 Common ftsA Cell division protein FtsA RF_1033 176 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 67459657 Common atpC F0F1 ATP synthase subunit epsilon RF_1265 111 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 67459681 Pathogen - hypothetical protein RF_1289 1 None None None 67459319 Common - Transposase RF_0927 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459701 Common map methionine aminopeptidase RF_1309 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 67459362 Common - Na+/proline symporter, signal transduction histidine kinase RF_0970 126 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 67458981 Common - hypothetical protein RF_0589 18 None None None 67458567 Common surf1 Surfeit locus protein 1 RF_0175 53 COG3346 COG3346, Uncharacterized conserved protein Function unknown 67459598 Common - PIN domain containing protein RF_1206 9 COG4374 COG4374, Uncharacterized protein conserved in bacteria Function unknown 67458936 Common - Efflux transporter, RND family, MFP subunit RF_0544 144 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 67459086 Common - hypothetical protein RF_0694 1 None None None 67459324 Pathogen - hypothetical protein RF_0932 1 None None None 67458771 Common - Transposase RF_0379 21 None None None 67458464 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase RF_0072 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 67459614 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase RF_1222 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 67459383 Common - hypothetical protein RF_0991 54 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 67458691 Common adk adenylate kinase RF_0299 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 67458915 Common - hypothetical protein RF_0523 1 None None None 67458792 Common - hypothetical protein RF_0400 61 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 67458707 Pathogen - hypothetical protein RF_0315 1 None None None 67458552 Pathogen - hypothetical protein RF_0160 1 None None None 67459599 Common - Transcriptional regulator RF_1207 3 None None None 67458778 Common - hypothetical protein RF_0386 4 None None None 67459103 Common - hypothetical protein RF_0711 8 None None None 67459482 Common - Thermostable carboxypeptidase RF_1090 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 67459115 Common truB tRNA pseudouridine synthase B RF_0723 243 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 67459305 Common - hypothetical protein RF_0913 47 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 67459760 Common - Cytotoxic translational repressor of toxin-antitoxin system RelE RF_1368 17 None None None 67459723 Pathogen - hypothetical protein RF_1331 1 None None None 67458511 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA RF_0119 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 67458755 Common - hypothetical protein RF_0363 1 None None None 67459216 Common trpS tryptophanyl-tRNA synthetase RF_0824 230 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67458518 Common - hypothetical protein RF_0126 1 None None None 67458999 Common msbA1 Multidrug resistance protein RF_0607 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 67459474 Common - hypothetical protein RF_1082 1 None None None 67459746 Common - hypothetical protein RF_1354 1 None None None 67458469 Common - hypothetical protein RF_0077 49 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 67459683 Common sca9 Cell surface antigen-like protein Sca9 RF_1291 1 None None None 67458785 Common - Transposase RF_0393 52 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459300 Common - hypothetical protein RF_0908 35 COG3177 COG3177, Uncharacterized conserved protein Function unknown 67458436 Common - hypothetical protein RF_0044 124 COG1678 COG1678, Putative transcriptional regulator Transcription 67459726 Common hemA 5-aminolevulinate synthase RF_1334 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 67459005 Common ispZ intracellular septation protein A RF_0613 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 67458603 Common - Lipoprotein releasing system, transmembrane protein RF_0211 182 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 67459139 Common - hypothetical protein RF_0747 1 None None None 67458524 Common - hypothetical protein RF_0132 64 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 67458839 Common - NACHT domain RF_0447 10 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 67458801 Common groEL chaperonin GroEL RF_0409 235 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 67458424 Common dsbG Protein-disulfide isomerase RF_0032 67 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 67458962 Common - Phage uncharacterized protein RF_0570 33 COG5362 COG5362, Phage-related terminase General function prediction only 67459524 Common - hypothetical protein RF_1132 128 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 67458493 Common - Transposase RF_0101 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459206 Common - Na+/proline symporter and signal transduction histidine kinase RF_0814 111 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 67458492 Common rplS 50S ribosomal protein L19 RF_0100 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 67459292 Common pbpA1 Penicillin-binding protein RF_0900 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 67459260 Common recO DNA repair protein RecO RF_0868 36 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 67459737 Common - Putative translation factor protein RF_1345 238 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 67459015 Common mccF Microcin C7 self-immunity protein RF_0623 81 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 67459353 Common ccmE cytochrome c-type biogenesis protein CcmE RF_0961 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 67459601 Pathogen - hypothetical protein RF_1209 1 None None None 67459430 Common - DUF2-containing protein RF_1038 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 67458717 Common fmt methionyl-tRNA formyltransferase RF_0325 219 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 67459267 Common - Putative transcriptional regulator RF_0875 111 COG1959 COG1959, Predicted transcriptional regulator Transcription 67459690 Common phaC Poly(3-hydroxyalkanoate) synthetase RF_1298 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 67458853 Common mnhC putative monovalent cation/H+ antiporter subunit C RF_0461 94 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 67458753 Pathogen - hypothetical protein RF_0361 1 None None None 67458586 Common - hypothetical protein RF_0194 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 67459347 Common - Proline/betaine transporter RF_0955 113 None None None 67458450 Common - hypothetical protein RF_0058 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 67459546 Common rpsG 30S ribosomal protein S7 RF_1154 246 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 67459279 Common - Large extracellular alpha-helical protein RF_0887 79 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 67459185 Common - Uncharacterized phage-associated protein RF_0793 25 COG3600 GepA, Uncharacterized phage-associated protein Function unknown 67458565 Common - hypothetical protein RF_0173 1 None None None 67458952 Common mpg 3-methyladenine DNA glycosylase RF_0560 84 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 67458602 Common lolD Lipoprotein releasing system ATP-binding protein LolD RF_0210 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 67458401 Common - Predicted esterase of the alpha-beta hydrolase superfamily RF_0009 12 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 67458959 Common nuoA NADH dehydrogenase subunit A RF_0567 163 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 67458536 Common - hypothetical protein RF_0144 1 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 67459333 Common secA preprotein translocase subunit SecA RF_0941 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 67458701 Common - MFS type sugar transporter RF_0309 138 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 67459464 Common - Transposase RF_1072 81 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459755 Common - hypothetical protein RF_1363 10 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 67459410 Common typA GTP-binding protein TypA RF_1018 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 67459527 Common - hypothetical protein RF_1135 2 None None None 67458891 Common - ABC transporter ATP-binding protein RF_0499 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 67458680 Common rplN 50S ribosomal protein L14 RF_0288 245 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 67458925 Common hflC1 Membrane protease subunits RF_0533 217 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 67459534 Common - Chromosome partitioning protein RF_1142 69 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 67458482 Common virB6_2 TrbL/VirB6 plasmid Conjugative transfer protein RF_0090 6 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 67458687 Common rpsE 30S ribosomal protein S5 RF_0295 244 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 67459676 Common - Iojap-related protein RF_1284 196 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 67458443 Common - Transposase RF_0051 42 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459557 Common - Predicted sulfurtransferase RF_1165 1 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 67458865 Pathogen - Cell surface antigen-like protein Sca7 RF_0473 1 None None None 67459280 Common - hypothetical protein RF_0888 13 None None None 67458850 Common nuoL2 putative monovalent cation/H+ antiporter subunit D RF_0458 207 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 67459411 Common pdhB pyruvate dehydrogenase subunit beta RF_1019 215 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 67459320 Common - hypothetical protein RF_0928 1 None None None 67458549 Pathogen - hypothetical protein RF_0157 1 COG3905 COG3905, Predicted transcriptional regulator Transcription 67459678 Common - Cytotoxic translational repressor of toxin-antitoxin system RelE RF_1286 16 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 67459259 Common - hypothetical protein RF_0867 2 None None None 67459085 Common sca3 Cell surface antigen Sca3 RF_0693 133 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 67459642 Common virB4_2 Type IV secretion/conjugal transfer ATPase, VirB4 family RF_1250 42 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 67458674 Common rpsS 30S ribosomal protein S19 RF_0282 244 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 67459393 Common prfB peptide chain release factor 2 RF_1001 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 67458963 Common xerD site-specific tyrosine recombinase XerD RF_0571 226 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 67459069 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase RF_0677 211 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 67459169 Common - Predicted metal-dependent hydrolase RF_0777 185 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 67459409 Common - hypothetical protein RF_1017 2 None None None 67459178 Common traC Possible DNA primase RF_0786 12 None None None 67459032 Common - RND family efflux transporter RF_0640 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 67458624 Common - hypothetical protein RF_0232 1 None None None 67459225 Common - hypothetical protein RF_0833 1 COG1279 COG1279, Lysine efflux permease General function prediction only 67458818 Common rpsU 30S ribosomal protein S21 RF_0426 2 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 67459269 Common tyrS tyrosyl-tRNA synthetase RF_0877 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67459158 Common sppA2 Signal peptide peptidase SppA RF_0766 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 67459375 Common - hypothetical protein RF_0983 2 None None None 67458893 Common - hypothetical protein RF_0501 1 None None None 67458938 Common - Predicted hydrolase or acyltransferase RF_0546 83 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 67458731 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase RF_0339 144 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 67458740 Common rpmH 50S ribosomal protein L34 RF_0348 193 None None None 67459341 Common - Predicted glutamine amidotransferase RF_0949 1 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 67458656 Common - ATP-dependent RNA helicase RhlE RF_0264 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 67459151 Common - hypothetical protein RF_0759 1 COG5346 COG5346, Predicted membrane protein Function unknown 67458672 Common rplW 50S ribosomal protein L23 RF_0280 3 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 67459468 Common coxC Cytochrome c oxidase subunit III RF_1076 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 67459453 Common rnhB ribonuclease HII RF_1061 208 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 67459365 Pathogen - hypothetical protein RF_0973 1 None None None 67458766 Common scoA Succinyl-CoA:3-ketoacid-coenzyme A transferase RF_0374 98 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 67458921 Common gltX glutamyl-tRNA synthetase RF_0529 248 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 67459364 Common - hypothetical protein RF_0972 4 None None None 67459431 Common bolA1 BolA protein homolog RF_1039 70 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 67458738 Common - hypothetical protein RF_0346 1 None None None 67459487 Common cutA Periplasmic divalent cation tolerance protein RF_1095 114 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 67459507 Pathogen - hypothetical protein RF_1115 1 None None None 67459670 Common miaB tRNA-i(6)A37 thiotransferase enzyme MiaB RF_1278 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 67458578 Common proP10 Proline/betaine transporter RF_0186 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67459274 Common - hypothetical protein RF_0882 1 None None None 67459023 Common nlpD2 Membrane proteins related to metalloendopeptidase RF_0631 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 67459541 Common rplA 50S ribosomal protein L1 RF_1149 245 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 67459413 Common xth1 Exodeoxyribonuclease III RF_1021 194 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 67458488 Common pta phosphate acetyltransferase RF_0096 122 COG0280 Pta, Phosphotransacetylase Energy production and conversion 67458509 Common soj ATPase involved in chromosome partitioning RF_0117 222 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 67459499 Common holB DNA polymerase III subunit delta' RF_1107 32 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 67459123 Common - Antitoxin of toxin-antitoxin system Phd RF_0731 6 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 67459051 Common ilvE branched-chain amino acid aminotransferase RF_0659 213 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 67458881 Common - Probable antitoxin of toxin-antitoxin stability system RF_0489 7 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 67458547 Common - hypothetical protein RF_0155 1 None None None 67458829 Common - transposase/IS protein RF_0437 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 67458612 Common - hypothetical protein RF_0220 25 COG5528 COG5528, Predicted integral membrane protein Function unknown 67458507 Common abcT1 putative ABC transporter ATP-binding protein RF_0115 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 67459498 Common ffh Signal recognition particle protein RF_1106 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 67458427 Common recF recombination protein F RF_0035 164 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 67459372 Pathogen - Acetyltransferase RF_0980 2 COG0456 RimI, Acetyltransferases General function prediction only 67459633 Common - S-adenosylmethionine synthetase MetK RF_1241 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 67459137 Common - hypothetical protein RF_0745 1 None None None 67459624 Common mreB Rod shape-determining protein MreB RF_1232 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 67459576 Pathogen - hypothetical protein RF_1184 1 None None None 67459697 Common - Outer memberane protein rOmpA RF_1305 60 None None None 67459147 Common - hypothetical protein RF_0755 25 COG5448 COG5448, Uncharacterized conserved protein Function unknown 67459132 Common folC Folylpolyglutamate synthase RF_0740 217 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 67459538 Common rpoB DNA-directed RNA polymerase subunit beta RF_1146 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 67459707 Common fdxA Ferredoxin RF_1315 165 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 67458990 Common - hypothetical protein RF_0598 8 None None None 67459037 Common dapF diaminopimelate epimerase RF_0645 198 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 67459291 Pathogen - Probable antitoxin of toxin-antitoxin system RF_0899 1 COG4710 COG4710, Predicted DNA-binding protein with an HTH domain General function prediction only 67458904 Common asd aspartate-semialdehyde dehydrogenase RF_0512 234 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 67459090 Common paaY Carbonic anhydrase/Acetyltransferase, isoleucine patch superfamily RF_0698 186 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 67458907 Common hslV ATP-dependent protease peptidase subunit RF_0515 152 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 67459067 Common ppnK inorganic polyphosphate/ATP-NAD kinase RF_0675 213 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 67459644 Common terC Tellurium resistance protein TerC RF_1252 90 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 67458750 Common bcr1 Bicyclomycin resistance protein RF_0358 164 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67459285 Common ubiH 2-octaprenyl-6-methoxyphenyl hydroxylase RF_0893 114 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 67459113 Common pnp polynucleotide phosphorylase/polyadenylase RF_0721 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 67459108 Common exoC Phosphomannomutase RF_0716 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 67459585 Pathogen - hypothetical protein RF_1193 1 None None None 162022119 Common rpsL 30S ribosomal protein S12 RF_1155 244 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 67458489 Common ackA Acetate kinase RF_0097 162 COG0282 ackA, Acetate kinase Energy production and conversion 67459043 Common leuS leucyl-tRNA synthetase RF_0651 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67459303 Common - Probable toxin of toxin-antitoxin system RF_0911 10 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 67459532 Common - Transposase RF_1140 53 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459059 Common - Acylamino-acid-releasing enzyme RF_0667 119 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 67458516 Common def3 Polypeptide deformylase RF_0124 209 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 67458477 Common - GTPase EngB RF_0085 187 COG0218 COG0218, Predicted GTPase General function prediction only 67459721 Common - hypothetical protein RF_1329 1 None None None 67458798 Common - hypothetical protein RF_0406 1 None None None 67459153 Common pdhC branched-chain alpha-keto acid dehydrogenase subunit E2 RF_0761 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 67458514 Common tlc1 ADP,ATP carrier protein RF_0122 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 67458724 Common - hypothetical protein RF_0332 1 None None None 67459748 Common truA tRNA pseudouridine synthase A RF_1356 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 67459441 Common efp elongation factor P RF_1049 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 67458418 Common - TPR repeats RF_0026 78 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 67459174 Pathogen - Ankyrin repeat RF_0782 1 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 67458787 Common - hypothetical protein RF_0395 1 None None None 67458582 Common - hypothetical protein RF_0190 1 None None None 67459296 Common mraW S-adenosyl-methyltransferase MraW RF_0904 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 67459685 Common maf Maf-like protein RF_1293 185 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 67458605 Common - hypothetical protein RF_0213 1 None None None 67459659 Common atpG F0F1 ATP synthase subunit gamma RF_1267 207 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 67459608 Common - hypothetical protein RF_1216 1 None None None 67458803 Common - Chitinase RF_0411 37 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 67458434 Common - hypothetical protein RF_0042 1 None None None 67459718 Common - DAP2-like protein RF_1326 10 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 67458499 Common parC DNA topoisomerase IV subunit A RF_0107 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 67458468 Common vacJ VacJ lipoprotein precursor RF_0076 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 67459229 Common tlc3 ADP,ATP carrier protein RF_0837 7 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 67459405 Common mnhB putative monovalent cation/H+ antiporter subunit B RF_1013 34 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 67458837 Common - hypothetical protein RF_0445 3 None None None 67459193 Common - hypothetical protein RF_0801 1 None None None 67459663 Common - Strees induced DNA-binding protein RF_1271 104 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 67459596 Common - Transposase RF_1204 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458440 Common - Cell surface antigen-like protein Sca10 RF_0048 1 None None None 67458715 Common - hypothetical protein RF_0323 2 None None None 67458944 Common - hypothetical protein RF_0552 11 None None None 67459515 Common - hypothetical protein RF_1123 1 None None None 67458807 Common znuB Zinc/manganese ABC transporter permease protein RF_0415 105 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 67459040 Common pheT phenylalanyl-tRNA synthetase subunit beta RF_0648 238 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 67459463 Common - Transposase RF_1071 52 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458415 Pathogen - hypothetical protein RF_0023 1 None None None 67459790 Common - hypothetical protein RF_1398 97 COG1981 COG1981, Predicted membrane protein Function unknown 67458790 Common - MFS type sugar transporter RF_0398 3 None None None 67458842 Common spoT1 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0450 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67458705 Common - hypothetical protein RF_0313 12 COG5449 COG5449, Uncharacterized conserved protein Function unknown 67459265 Common - hypothetical protein RF_0873 167 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 67458913 Common - hypothetical protein RF_0521 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 67458693 Common rpsK 30S ribosomal protein S11 RF_0301 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 67458396 Common rfbA O-antigen export system permease protein RfbA RF_0004 107 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 67459183 Pathogen - hypothetical protein RF_0791 1 None None None 67458626 Common tdk thymidylate kinase RF_0234 225 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 67458403 Common - Ankyrin repeat RF_0011 1 None None None 67459373 Common mdlB ABC-type multidrug transport system, ATPase and permease components RF_0981 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 67458452 Common ompW OmpW family outer-membrane protein RF_0060 42 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 67458642 Common xth2 Exodeoxyribonuclease III RF_0250 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 67458534 Common rpsR 30S ribosomal protein S18 RF_0142 208 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 67458898 Common - Periplasmic protein TonB RF_0506 9 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 67459448 Pathogen - hypothetical protein RF_1056 1 None None None 67458934 Common - hypothetical protein RF_0542 27 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 67458923 Common dprA Putatie DNA processing protein DprA RF_0531 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 67459619 Common - Predicted ATPase RF_1227 34 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 67459521 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A RF_1129 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 67459554 Common - NT (nucleotidyltransferase) domain and HEPN (higher eukarytoes and prokaryotes nucleotide-binding) domain RF_1162 9 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 67459771 Common - hypothetical protein RF_1379 1 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 67459459 Common uspA Universal stress protein UspA RF_1067 39 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 67458960 Common - hypothetical protein RF_0568 3 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 67459359 Common - Transposase RF_0967 29 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459472 Pathogen - hypothetical protein RF_1080 1 None None None 67459692 Common surA Parvulin-like peptidyl-prolyl isomerase RF_1300 89 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 67459505 Common - hypothetical protein RF_1113 101 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 67459072 Common - Predicted hydrolase or acyltransferase RF_0680 73 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 67458399 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase RF_0007 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 67458584 Common ligA NAD-dependent DNA ligase LigA RF_0192 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 67458490 Pathogen - hypothetical protein RF_0098 1 None None None 67458554 Common phbC Poly-beta-hydroxybutyrate polymerase RF_0162 46 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 67459294 Common pbpA2 Penicillin-binding protein RF_0902 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 67459332 Common - NT (nucleotidyltransferase) domain and HEPN (higher eukarytoes and prokaryotes nucleotide-binding) domain RF_0940 9 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 67458773 Common spoT13 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0381 216 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67458665 Common fumC fumarate hydratase RF_0273 229 COG0114 FumC, Fumarase Energy production and conversion 67458816 Common - Excinuclease ABC, C subunit, N-terminal RF_0424 43 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 67459167 Common - Acetyltransferase RF_0775 6 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 67459447 Common gyrA DNA gyrase subunit A RF_1055 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 67458993 Common - Antitoxin of toxin-antitoxin system StbD RF_0601 2 None None None 67459227 Common - hypothetical protein RF_0835 23 None None None 67458722 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase RF_0330 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 67458648 Common ksgA dimethyladenosine transferase RF_0256 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 67459699 Common ftsK Cell division protein FtsK-like protein RF_1307 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 67458540 Pathogen - hypothetical protein RF_0148 1 None None None 67458689 Common rplO 50S ribosomal protein L15 RF_0297 65 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 67459379 Common - Ankyrin repeat RF_0987 1 COG5373 COG5373, Predicted membrane protein Function unknown 67459661 Common atpH F0F1 ATP synthase subunit delta RF_1269 51 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 67459635 Common - hypothetical protein RF_1243 17 None None None 67459343 Common mgtE Magnesium transporter RF_0951 160 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 67458658 Common - Ankyrin repeat RF_0266 3 None None None 67459214 Pathogen - hypothetical protein RF_0822 1 None None None 67458682 Common rplE 50S ribosomal protein L5 RF_0290 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 67458859 Common virB10 VirB10 protein RF_0467 58 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 67459035 Common - RND efflux system, outer membrane protein RF_0643 116 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 67459176 Common - Predicted acetyltransferase RF_0784 11 COG3393 COG3393, Predicted acetyltransferase General function prediction only 67458571 Common - hypothetical protein RF_0179 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 67458708 Common - hypothetical protein RF_0316 1 None None None 67459313 Common - Transposase RF_0921 53 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458668 Common tuf elongation factor Tu RF_0276 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 67459433 Common - hypothetical protein RF_1041 2 None None None 67459761 Common - Antitoxin of toxin-antitoxin system StbD RF_1369 24 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 67458867 Common - Cell surface antigen-like protein Sca7 RF_0475 94 None None None 67458749 Common - hypothetical protein RF_0357 9 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 67458736 Common - transposase/IS protein RF_0344 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 67458747 Common ychF translation-associated GTPase RF_0355 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 162022125 Common rpsF 30S ribosomal protein S6 RF_0143 198 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 67458984 Common tlc2 ADP,ATP carrier protein RF_0592 7 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 67458645 Common xseA exodeoxyribonuclease VII large subunit RF_0253 204 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 67458453 Common sam S-adenosylmethionine transporter RF_0061 68 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 67458560 Common - hypothetical protein RF_0168 11 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 67458441 Common - Transposase RF_0049 64 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459395 Common - hypothetical protein RF_1003 1 None None None 67458593 Common himA Integration host factor alpha-subunit RF_0201 79 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 67459252 Common dnaB replicative DNA helicase RF_0860 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 67458870 Common - Cell surface antigen-like protein Sca7 RF_0478 1 None None None 67458618 Common - Predicted ATPase RF_0226 63 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 67459428 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase RF_1036 169 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 67459060 Common - hypothetical protein RF_0668 7 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 67459094 Common - Antitoxin of toxin-antitoxin system Phd RF_0702 3 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 67459064 Common recR recombination protein RecR RF_0672 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 67459766 Common - Predicted permeases RF_1374 35 COG0795 COG0795, Predicted permeases General function prediction only 67458563 Common fabD acyl-carrier-protein S-malonyltransferase RF_0171 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 67459572 Common - hypothetical protein RF_1180 37 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 67458447 Common secB preprotein translocase subunit SecB RF_0055 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 67458533 Common rplI 50S ribosomal protein L9 RF_0141 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 67458854 Common virB9_1 VirB9 protein RF_0462 56 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 67458932 Common rffE UDP-N-acetylglucosamine 2-epimerase RF_0540 155 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 67458876 Common - hypothetical protein RF_0484 2 None None None 67459773 Common nhaA Na+/H+ antiporter NhaA RF_1381 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 67459594 Common - hypothetical protein RF_1202 77 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 67458869 Common - Cell surface antigen-like protein Sca7 RF_0477 1 None None None 67458580 Common - Guanosine polyphosphate pyrophosphohydrolase/synthetase-like protein SpoT4 RF_0188 2 None None None 67458666 Common - hypothetical protein RF_0274 1 None None None 67458414 Common sca1 Cell surface antigen Sca1 RF_0022 13 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 67459390 Common - Transposase RF_0998 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459461 Common pbpC Bifunctional penicillin-binding protein 1C RF_1069 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 67458531 Common ftsH ATP-dependent metalloprotease FtsH RF_0139 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 67459579 Common lipA lipoyl synthase RF_1187 191 COG0320 LipA, Lipoate synthase Coenzyme metabolism 67458720 Common n2B Putative ATPase n2B RF_0328 96 COG1485 COG1485, Predicted ATPase General function prediction only 67458757 Common pspE Rhodanese-related sulfurtransferase RF_0365 43 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 67458844 Common - MFS type sugar transporter RF_0452 115 None None None 67458992 Common proS prolyl-tRNA synthetase RF_0600 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67459164 Common clpP ATP-dependent Clp protease proteolytic subunit RF_0772 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 67459567 Common - TPR repeats RF_1175 77 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 67459212 Pathogen - Predicted hydrolase or acyltransferase RF_0820 3 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 67459560 Common hflK Protease activity modulator HflK RF_1168 157 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 67458699 Common - Transposase RF_0307 42 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458781 Common - Transposase RF_0389 42 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458995 Common - hypothetical protein RF_0603 1 None None None 67459220 Common - hypothetical protein RF_0828 89 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 67459420 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase RF_1028 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 67459160 Common - hypothetical protein RF_0768 1 None None None 67458734 Common - Transposase RF_0342 69 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459154 Common prfA peptide chain release factor 1 RF_0762 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 67459647 Common nuoJ NADH dehydrogenase subunit J RF_1255 157 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 67458814 Common - hypothetical protein RF_0422 1 None None None 67458545 Common phbB acetoacetyl-CoA reductase RF_0153 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 67459416 Common coxW Cytochrome c oxidase assembly protein RF_1024 55 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 67458651 Common - Protein phosphatase RF_0259 141 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 67458744 Common rplY 50S ribosomal protein L25/general stress protein Ctc RF_0352 191 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 67459429 Common murC UDP-N-acetylmuramate--L-alanine ligase RF_1037 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 67458528 Common sdhB succinate dehydrogenase iron-sulfur subunit RF_0136 191 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 67458874 Common cysQ 3'(2'),5'-bisphosphate nucleotidase RF_0482 189 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 67459517 Common mnhE putative monovalent cation/H+ antiporter subunit E RF_1125 25 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 67459788 Common hemF coproporphyrinogen III oxidase RF_1396 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 67459578 Common - hypothetical protein RF_1186 118 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 67458644 Common - hypothetical protein RF_0252 1 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 67459618 Common - hypothetical protein RF_1226 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 67458712 Common - Transposase RF_0320 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458889 Common atrC1 Cationic amino acid transporter-1 RF_0497 193 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 67459242 Common - hypothetical protein RF_0850 1 None None None 67459470 Common holA DNA polymerase III subunit delta RF_1078 26 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 67459256 Common - Uncharacterized low-complexity protein RF_0864 64 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 67459007 Common - hypothetical protein RF_0615 19 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 67458966 Common - hypothetical protein RF_0574 1 None None None 67458430 Common - Dihydrofolate reductase FolA RF_0038 25 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 67459500 Common hupA DNA-binding protein HU RF_1108 199 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 67459071 Common - Predicted permease RF_0679 16 COG0679 COG0679, Predicted permeases General function prediction only 67459339 Common gyrB DNA gyrase subunit B RF_0947 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 67458627 Common metG methionyl-tRNA synthetase RF_0235 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67458710 Pathogen - hypothetical protein RF_0318 1 COG4187 RocB, Arginine degradation protein (predicted deacylase) Amino acid transport and metabolism 67458420 Common atpX F0F1 ATP synthase subunit B' RF_0028 32 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 67458538 Common gcp O-sialoglycoprotein endopeptidase RF_0146 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 67458897 Common tolR TolR protein RF_0505 141 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 67458495 Common - Transposase RF_0103 80 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459551 Common sdhA succinate dehydrogenase flavoprotein subunit RF_1159 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 67458454 Common proP1 Proline/betaine transporter RF_0062 131 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 67459668 Common mrcA Penicillin-binding protein 1A family RF_1276 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 67458405 Common - hypothetical protein RF_0013 1 None None None 67459181 Common - hypothetical protein RF_0789 1 None None None 67458929 Common - Transcriptional regulator, AbrB family RF_0537 1 None None None 67459399 Common fbcH Cytochrome c1, heme protein precursor RF_1007 75 COG2857 CYT1, Cytochrome c1 Energy production and conversion 67459509 Common - hypothetical protein RF_1117 2 None None None 67458589 Common htrB lipid A biosynthesis lauroyl acyltransferase RF_0197 118 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 67459751 Common sec59 Dolichol kinase RF_1359 5 COG0170 SEC59, Dolichol kinase Lipid metabolism 67459536 Common - hypothetical protein RF_1144 1 None None None 67458918 Common bioY1 BioY family protein RF_0526 41 COG1268 BioY, Uncharacterized conserved protein General function prediction only 67459298 Common panF Sodium/pantothenate symporter RF_0906 125 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 67458920 Pathogen - hypothetical protein RF_0528 1 None None None 67459352 Common - Sco2 protein precursor RF_0960 109 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 67459407 Common icd isocitrate dehydrogenase RF_1015 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 67458579 Common - Guanosine polyphosphate pyrophosphohydrolase/synthetase-like protein SpoT4 RF_0187 202 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67459549 Pathogen - hypothetical protein RF_1157 1 None None None 67459605 Common - NAD-specific glutamate dehydrogenase RF_1213 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 67458988 Common - hypothetical protein RF_0596 3 None None None 67458486 Common vapB2 Antitoxin of toxin-antitoxin system VapB RF_0094 25 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 67458969 Common - hypothetical protein RF_0577 40 COG1395 COG1395, Predicted transcriptional regulator Transcription 67459477 Common dnaJ DnaJ protein RF_1085 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 67459666 Pathogen - hypothetical protein RF_1274 1 None None None 67459047 Common cdsA Phosphatidate cytidylyltransferase RF_0655 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 67459254 Common - Putative to amino acid permeases RF_0862 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 67459084 Common lon ATP-dependent protease La RF_0692 210 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 67458678 Common rpmC 50S ribosomal protein L29 RF_0286 1 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 67458457 Common - Transposase RF_0065 80 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459595 Common - hypothetical protein RF_1203 76 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 67459763 Common phnP Metal-dependent hydrolase of the beta-lactamase superfamily I RF_1371 92 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 67459350 Common yajC preprotein translocase subunit YajC RF_0958 22 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 67458808 Common - hypothetical protein RF_0416 31 COG3070 TfoX, Regulator of competence-specific genes Transcription 67458607 Common - hypothetical protein RF_0215 3 None None None 67458556 Common - hypothetical protein RF_0164 1 None None None 67458475 Common rpmB 50S ribosomal protein L28 RF_0083 109 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 67459036 Common - Glycosyltransferase RF_0644 230 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 67458804 Common - hypothetical protein RF_0412 1 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 67459741 Common proP6 Proline/betaine transporter RF_1349 134 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 67458616 Common - hypothetical protein RF_0224 2 None None None 67459327 Common - hypothetical protein RF_0935 2 None None None 67459687 Common xerC site-specific tyrosine recombinase XerC RF_1295 224 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 67458471 Common alr alanine racemase RF_0079 198 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 67458977 Common - hypothetical protein RF_0585 3 COG5307 COG5307, SEC7 domain proteins General function prediction only 67459446 Common - Transposase RF_1054 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459166 Common - Streptomycin 6-kinase RF_0774 28 COG3570 StrB, Streptomycin 6-kinase Defense mechanisms 67459130 Common - Biotin-protein ligase RF_0738 1 COG4285 COG4285, Uncharacterized conserved protein Function unknown 162022120 Common fusA elongation factor G RF_1153 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 67459304 Common uvrC excinuclease ABC subunit C RF_0912 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 67458832 Common spoT8 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0440 204 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67459309 Pathogen - hypothetical protein RF_0917 1 None None None 67458439 Common - Cell surface antigen-like protein Sca10 RF_0047 6 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 67458512 Common ndk nucleoside diphosphate kinase RF_0120 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 67459611 Common - Multidrug resistance transporter protein RF_1219 108 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67459486 Common - 6-pyruvoyl tetrahydropterin synthase RF_1094 95 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 67458462 Common tsf elongation factor Ts RF_0070 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 67459720 Common - MFS type sugar transporter RF_1328 1 None None None 67458811 Common accC Acetyl-CoA carboxylase, biotin carboxylase RF_0419 240 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 67459262 Pathogen - hypothetical protein RF_0870 1 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 67458847 Common nuoL3 putative monovalent cation/H+ antiporter subunit D RF_0455 182 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 67458503 Common iscA1 Iron-sulfur cluster assembly accessory protein RF_0111 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 67459236 Common iscU scaffold protein RF_0844 146 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 67458971 Common - ABC transporter permease protein RF_0579 46 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 67458632 Common - hypothetical protein RF_0240 1 None None None 67459016 Common - hypothetical protein RF_0624 50 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 67459038 Common - MiaB-like tRNA modifying enzyme RF_0646 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 67459240 Common - hypothetical protein RF_0848 1 None None None 67459101 Common nrdA ribonucleotide-diphosphate reductase subunit alpha RF_0709 221 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 67459126 Common - hypothetical protein RF_0734 2 None None None 67459234 Common - hypothetical protein RF_0842 2 None None None 67459754 Common pntA1 NAD(P) transhydrogenase subunit alpha RF_1362 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 67459135 Common - Predicted esterase of the alpha-beta hydrolase superfamily RF_0743 6 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 67458903 Common aprD Alkaline protease secretion ATP-binding protein AprD RF_0511 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 162022116 Common - hypothetical protein RF_1332 17 COG1872 COG1872, Uncharacterized conserved protein Function unknown 67458621 Common valS valyl-tRNA synthetase RF_0229 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67459731 Common - Predicted transcriptional regulator RF_1339 4 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 67459042 Common - hypothetical protein RF_0650 18 None None None 67458636 Common ubiB 2-polyprenylphenol 6-hydroxylase RF_0244 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 67459651 Common ccmA Heme exporter protein A RF_1259 243 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 67458958 Common nuoB NADH dehydrogenase subunit B RF_0566 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 67459786 Common - TPR RF_1394 171 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 67459582 Common grxC2 Glutaredoxin-like protein grla RF_1190 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 67458857 Common virB8_2 VirB8 protein RF_0465 26 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 67459276 Common spoT9 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0884 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67458599 Common ccmF Cytochrome c-type biogenesis protein CcmF RF_0207 138 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 67459386 Common rplM 50S ribosomal protein L13 RF_0994 215 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 67459111 Common - hypothetical protein RF_0719 2 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 67459520 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C RF_1128 100 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 67459458 Common imp TRAP-type uncharacterized transport system RF_1066 70 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 67458416 Common - hypothetical protein RF_0024 1 None None None 67458523 Common yidC putative inner membrane protein translocase component YidC RF_0131 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 67459658 Common atpD F0F1 ATP synthase subunit beta RF_1266 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 67458774 Common - Transposase RF_0382 8 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459028 Common murG N-acetylglucosaminyl transferase RF_0636 209 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 67459096 Common - hypothetical protein RF_0704 14 COG3121 FimC, P pilus assembly protein, chaperone PapD Cell motility and secretion / Intracellular trafficking and secretion 67458761 Common murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase RF_0369 210 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 67458696 Common rpsT 30S ribosomal protein S20 RF_0304 149 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 67459626 Common pal Peptidoglycan-associated lipoprotein precursor RF_1234 149 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 67458421 Common atpE F0F1 ATP synthase subunit C RF_0029 68 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 67458478 Common argB Acetylglutamate kinase RF_0086 167 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 67459312 Common - Transposase RF_0920 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459589 Common pgpA Phosphatidylglycerophosphatase A RF_1197 56 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 67458795 Common rph ribonuclease PH RF_0403 180 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 67459543 Common nusG transcription antitermination protein NusG RF_1151 216 COG0250 NusG, Transcription antiterminator Transcription 67459377 Common tolC Type I secretion outer membrane protein, TolC family RF_0985 123 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 67459142 Common - Phage prohead protease (HK97 family) and phage major capsid protein (HK97 family) RF_0750 47 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 67459704 Common - hypothetical protein RF_1312 1 None None None 67459705 Common - hypothetical protein RF_1313 1 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 67459637 Common udg UDP-glucose 6-dehydrogenase RF_1245 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 67458572 Common rnhA ribonuclease H RF_0180 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 67459210 Common - hypothetical protein RF_0818 1 None None None 67458684 Common rpsH 30S ribosomal protein S8 RF_0292 231 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 67458590 Common bcp Bacterioferritin comigratory protein RF_0198 224 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 67458769 Pathogen - hypothetical protein RF_0377 1 None None None 67459620 Common - Predicted ATPase RF_1228 16 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 67459451 Common grxC1 Glutaredoxin, GrxC family RF_1059 110 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 67458900 Common spoT2 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0508 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67458939 Common - Glycosyltransferase RF_0547 186 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 67459162 Common cmk cytidylate kinase RF_0770 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 67458783 Common proP Permeases of the major facilitator superfamily RF_0391 116 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67459422 Common cycM Cytochrome c RF_1030 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 67459649 Common nuoL1 NADH dehydrogenase subunit L RF_1257 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 67459222 Common - hypothetical protein RF_0830 1 None None None 67459735 Common - Growth inhibitor RF_1343 12 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 67458872 Common - hypothetical protein RF_0480 2 None None None 67458526 Common - hypothetical protein RF_0134 91 COG1565 COG1565, Uncharacterized conserved protein Function unknown 67459655 Common - hypothetical protein RF_1263 16 COG3671 COG3671, Predicted membrane protein Function unknown 67458812 Pathogen - hypothetical protein RF_0420 1 None None None 67459348 Common - Cytotoxic translational repressor of toxin-antitoxin system RelE RF_0956 32 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 67459356 Common traX F pilin acetylation protein TraX RF_0964 3 None None None 67459502 Common - hypothetical protein RF_1110 14 COG2155 COG2155, Uncharacterized conserved protein Function unknown 67458686 Common rplR 50S ribosomal protein L18 RF_0294 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 67459603 Common - hypothetical protein RF_1211 1 None None None 67459197 Pathogen - hypothetical protein RF_0805 1 None None None 67459118 Common hipB Predicted transcriptional regulator RF_0726 40 COG1396 HipB, Predicted transcriptional regulators Transcription 67458821 Pathogen - Putative lipoprotein RF_0429 4 None None None 67458653 Pathogen - hypothetical protein RF_0261 1 None None None 67458445 Common - Putative surface antigen RF_0053 6 None None None 67459768 Common dapE succinyl-diaminopimelate desuccinylase RF_1376 217 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 67458776 Common spoT15 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0384 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67458732 Pathogen - hypothetical protein RF_0340 1 None None None 67458752 Common pat1 Patatin-like phospholipase RF_0360 32 COG3621 COG3621, Patatin General function prediction only 67459569 Common lepB Signal peptidase I RF_1177 198 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 67459009 Common - Protocatechuate-3,4-dioxygenase, beta subunit RF_0617 27 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 67459078 Common lgtD Glycosyltransferase RF_0686 202 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 67458664 Common - Antitoxin of toxin-antitoxin system Phd RF_0272 4 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 67458587 Common - Periplasmic protein RF_0195 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 67459062 Common - Predicted membrane protein RF_0670 5 COG1238 COG1238, Predicted membrane protein Function unknown 67458456 Common - hypothetical protein RF_0064 1 None None None 67458860 Common virB11 VirB11 protein RF_0468 152 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 67458411 Common pcnB Poly(A) polymerase RF_0019 209 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 67458759 Common mfd Transcription-repair coupling factor RF_0367 222 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 67458824 Common - hypothetical protein RF_0432 5 None None None 67458629 Common - hypothetical protein RF_0237 17 COG2958 COG2958, Uncharacterized protein conserved in bacteria Function unknown 67459664 Common - Cytotoxic translational repressor of toxin-antitoxin system RelE RF_1272 15 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 67459392 Common lepA GTP-binding protein LepA RF_1000 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 67459436 Common emrA Multidrug resistance protein A RF_1044 135 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 67459342 Common - Ankyrin repeat RF_0950 68 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 67458407 Common - Antitoxin of toxin-antitoxin system StbD RF_0015 10 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 67459330 Common - hypothetical protein RF_0938 2 None None None 67458895 Common - hypothetical protein RF_0503 1 None None None 67459739 Common glyQ glycyl-tRNA synthetase subunit alpha RF_1347 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 67459010 Common tlpA Thiol:disulfide interchange protein TlpA RF_0618 126 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 67458927 Common - Holliday junction resolvase-like protein RF_0535 186 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 67459792 Common hemE uroporphyrinogen decarboxylase RF_1400 179 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 67459592 Common lysC aspartate kinase RF_1200 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 67459376 Common - hypothetical protein RF_0984 21 None None None 67459317 Common - hypothetical protein RF_0925 2 None None None 67459418 Common - hypothetical protein RF_1026 1 None None None 67459641 Common serS seryl-tRNA synthetase RF_1249 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 67459494 Common - Transposase RF_1102 11 None None None 67458862 Common gppA Guanosine pentaphosphate phosphohydrolase RF_0470 99 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 67459000 Common ampG4 AmpG protein RF_0608 109 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 67459574 Common - Transposase RF_1182 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459188 Pathogen - rRNA methylase RF_0796 1 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 67459540 Common rplJ 50S ribosomal protein L10 RF_1148 215 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 67459562 Common - hypothetical protein RF_1170 13 COG3660 COG3660, Predicted nucleoside-diphosphate-sugar epimerase Cell envelope biogenesis, outer membrane 67459401 Common petB Cytochrome b RF_1009 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 67458967 Common fabI enoyl-(acyl carrier protein) reductase RF_0575 221 COG0623 FabI, Enoyl- acyl-carrier-protein 67459258 Common radA DNA repair protein RadA RF_0866 201 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 67459590 Common rplU 50S ribosomal protein L21 RF_1198 208 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 67459778 Common rpmG 50S ribosomal protein L33 RF_1386 124 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 67458964 Common - hypothetical protein RF_0572 1 None None None 67458852 Common nuoN2 putative monovalent cation/H+ antiporter subunit D RF_0460 204 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 67458930 Common - dTDP-4-dehydrorhamnose reductase RF_0538 112 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 67459019 Common coxA Cytochrome c oxidase polypeptide I RF_0627 169 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 67459616 Common fabF 3-oxoacyl-(acyl carrier protein) synthase II RF_1224 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 67459179 Common - Toxin of toxin-antitoxin system ParE RF_0787 2 COG3668 ParE, Plasmid stabilization system protein General function prediction only 67459251 Common ubiX aromatic acid decarboxylase RF_0859 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 67459357 Common - hypothetical protein RF_0965 4 None None None 67458459 Common sca2 Cell surface antigen Sca2 RF_0067 3 None None None 67459129 Common - Biotin-protein ligase RF_0737 1 COG4285 COG4285, Uncharacterized conserved protein Function unknown 67459307 Common - Methylated-DNA--protein-cysteine methyltransferase RF_0915 189 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 67458956 Common nuoD NADH dehydrogenase subunit D RF_0564 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 67459408 Common - hypothetical protein RF_1016 19 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 67459337 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase RF_0945 208 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 67459056 Common sucD succinyl-CoA synthetase subunit alpha RF_0664 211 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 67458600 Common - Hemolysin homolog RF_0208 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 67459156 Common - Putative methyltransferase RF_0764 26 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 67458558 Common - Sugar kinase RF_0166 147 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 67458698 Common - transposase/IS protein RF_0306 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 67459325 Common - Phage-related lysozyme RF_0933 4 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 67459419 Common - hypothetical protein RF_1027 1 None None None 67459743 Common - hypothetical protein RF_1351 1 None None None 67459489 Common - hypothetical protein RF_1097 9 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 67459630 Common ftsY Signal recognition particle-docking protein FtsY RF_1238 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 67458437 Common cvpA hypothetical protein RF_0045 7 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 67458551 Common - Transposase RF_0159 52 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458395 Common rfbE O-antigen export system ATP-binding protein RfbE RF_0003 246 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 67459088 Common - hypothetical protein RF_0696 2 None None None 67458609 Common exsB Trans-regulatory protein ExsB RF_0217 176 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 67459689 Common - Phospholipase D (PLD) superfamily protein RF_1297 51 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 67459044 Pathogen - hypothetical protein RF_0652 1 None None None 67459550 Pathogen - hypothetical protein RF_1158 1 None None None 67459021 Common coxB Cytochrome c oxidase polypeptide II RF_0629 154 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 67458703 Common - hypothetical protein RF_0311 2 COG5304 COG5304, Uncharacterized protein conserved in bacteria Function unknown 67459104 Common - hypothetical protein RF_0712 1 None None None 67458830 Common spoT7 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0438 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67459628 Common rpmF 50S ribosomal protein L32 RF_1236 67 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 67458916 Common - hypothetical protein RF_0524 2 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 67459030 Common - hypothetical protein RF_0638 1 None None None 67459170 Pathogen - hypothetical protein RF_0778 1 None None None 67459444 Pathogen - hypothetical protein RF_1052 1 None None None 67459775 Common lipB lipoyltransferase RF_1383 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 67459389 Common - Putative pterin-4-alpha-carbinolamine dehydratase (PHS) RF_0997 99 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 67458543 Common - hypothetical protein RF_0151 3 None None None 67458634 Common mutM Formamidopyrimidine-DNA glycosidase RF_0242 183 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 67458911 Common lpxB lipid-A-disaccharide synthase RF_0519 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 67459219 Common relB2 DNA-damage-inducible protein J RF_0827 23 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 67459479 Common - Ankyrin repeat RF_1087 50 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 67459529 Common - Penicillin acylase RF_1137 51 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 67459302 Common - Antitoxin of toxin-antitoxin system StbD RF_0910 16 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 67459674 Common - hypothetical protein RF_1282 42 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 67459526 Common - Integral membrane protein RF_1134 130 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 67459282 Common fadB 3-hydroxyacyl-CoA dehydrogenase FadB RF_0890 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 67459533 Pathogen - hypothetical protein RF_1141 1 None None None 67458719 Common - hypothetical protein RF_0327 2 None None None 67458793 Common perM Permease PerM homolog RF_0401 113 COG0628 PerM, Predicted permease General function prediction only 67459480 Common - hypothetical protein RF_1088 114 COG4105 ComL, DNA uptake lipoprotein General function prediction only 67458597 Common rompB Outer membrane protein B RF_0205 121 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 67459082 Common - hypothetical protein RF_0690 1 None None None 67458444 Common - Transposase RF_0052 69 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458998 Common ruvB Holliday junction DNA helicase B RF_0606 218 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 67458466 Common aatA aspartate aminotransferase RF_0074 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 67459382 Common barA Histidine kinase sensor protein RF_0990 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 67458473 Common mkl Ribonucleotide ABC transporter ATP-binding protein RF_0081 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 67459271 Common - hypothetical protein RF_0879 1 None None None 67458521 Common - hypothetical protein RF_0129 9 None None None 67458763 Common rickA Actin polymerization protein RickA RF_0371 37 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 67459710 Common ccmC Heme exporter protein C RF_1318 114 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 67458510 Common gidB glucose-inhibited division protein B RF_0118 150 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 67459026 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase RF_0634 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 67458400 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase RF_0008 170 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 67458574 Common - ABC transporter substrate binding protein RF_0182 81 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 67458423 Common - hypothetical protein RF_0031 3 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 67459289 Common - hypothetical protein RF_0897 1 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 67459144 Common - hypothetical protein RF_0752 2 None None None 67459467 Common trbC VirB2 protein homolog RF_1075 1 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 67458638 Common - hypothetical protein RF_0246 1 None None None 67459702 Common radC DNA repair protein RadC RF_1310 168 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 67459172 Common - hypothetical protein RF_0780 97 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 67458742 Common rpmI 50S ribosomal protein L35 RF_0350 104 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 67459622 Common - hypothetical protein RF_1230 1 None None None 67458979 Common - Transposase RF_0587 52 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458661 Pathogen - hypothetical protein RF_0269 1 None None None 67459456 Common fdxB Ferredoxin RF_1064 100 COG0633 Fdx, Ferredoxin Energy production and conversion 67458948 Common - hypothetical protein RF_0556 13 None None None 67458822 Common - hypothetical protein RF_0430 7 None None None 67459149 Common - hypothetical protein RF_0757 7 COG5449 COG5449, Uncharacterized conserved protein Function unknown 67459423 Common - hypothetical protein RF_1031 7 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 67458974 Common lysK lysyl-tRNA synthetase RF_0582 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 67459232 Common pepP Aminopeptidase P RF_0840 209 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 67459204 Common - hypothetical protein RF_0812 1 None None None 67459653 Common nuoH NADH dehydrogenase subunit H RF_1261 187 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 67459370 Common - hypothetical protein RF_0978 5 None None None 67459106 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase RF_0714 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 67459511 Common nusB transcription antitermination protein NusB RF_1119 63 COG0781 NusB, Transcription termination factor Transcription 67459049 Common envZ Osmolarity sensor protein EnvZ RF_0657 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 67458729 Common lgtF Beta 1,4 glucosyltransferase RF_0337 111 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 67459190 Common glmU UDP-N-acetylglucosamine pyrophosphorylase RF_0798 216 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 67459367 Common - Transposase RF_0975 69 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458639 Common - Predicted ATPase RF_0247 58 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 67459510 Common rrmJ Ribosomal RNA large subunit methyltransferase J RF_1118 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 67459077 Common - hypothetical protein RF_0685 1 None None None 67459128 Common - Glutathione S-transferase RF_0736 62 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 67459133 Common sodB Superoxide dismutase RF_0741 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 67459740 Common - hypothetical protein RF_1348 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 67459053 Common smpB SsrA-binding protein RF_0661 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 67459563 Common - Nucleotidyltransferase substrate binding protein RF_1171 8 None None None 67459346 Common - Proline/betaine transporter RF_0954 1 None None None 67459244 Pathogen - hypothetical protein RF_0852 1 None None None 67458676 Common rpsC 30S ribosomal protein S3 RF_0284 241 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 67459388 Common - D-alanyl-D-alanine dipeptidase RF_0996 37 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 67459121 Common - hypothetical protein RF_0729 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 67459360 Common spoT10 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0968 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67458849 Common vapB1 Antitoxin of toxin-antitoxin system VapB RF_0457 1 None None None 162022124 Common groES co-chaperonin GroES RF_0408 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 67459504 Common - hypothetical protein RF_1112 3 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 67459691 Common ubiD UbiD family decarboxylase RF_1299 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 67458772 Common spoT6 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0380 23 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67458754 Common - hypothetical protein RF_0362 1 None None None 67458961 Common - hypothetical protein RF_0569 17 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 67459293 Common - hypothetical protein RF_0901 2 None None None 67458404 Common nifR3 Putative TIM-barrel protein, nifR3 family RF_0012 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 67458491 Common trmD tRNA (guanine-N(1)-)-methyltransferase RF_0099 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 67458951 Common - hypothetical protein RF_0559 1 None None None 67459475 Common - Heat shock protease RF_1083 204 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 67459600 Common proP5 Proline/betaine transporter RF_1208 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67459465 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase RF_1073 143 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 67458706 Common - Ankyrin repeat RF_0314 14 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 67458791 Common - MFS type sugar transporter RF_0399 68 None None None 67458935 Common - Two-domain glycosyltransferase RF_0543 206 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 67458692 Common rpsM 30S ribosomal protein S13 RF_0300 232 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 67459770 Common - Type I restriction-modification system methyltransferase subunit RF_1378 1 None None None 67459629 Common - hypothetical protein RF_1237 18 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 67458924 Common tdpX1 Thioredoxin peroxidase 1 RF_0532 224 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 67458575 Common - hypothetical protein RF_0183 1 None None None 67458688 Common rpmD 50S ribosomal protein L30 RF_0296 144 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 67459278 Common - hypothetical protein RF_0886 28 None None None 67458596 Common spoT11 Guanosine polyphosphate pyrophosphohydrolase/synthetase-like protein RF_0204 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67459002 Pathogen - hypothetical protein RF_0610 1 None None None 67459438 Common psd phosphatidylserine decarboxylase RF_1046 96 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 67458601 Common - hypothetical protein RF_0209 2 COG5160 ULP1, Protease, Ulp1 family Posttranslational modification, protein turnover, chaperones 67458669 Common rpsJ 30S ribosomal protein S10 RF_0277 234 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 67458730 Common mpp Mpp RF_0338 200 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 67458858 Common virB9_2 VirB9 protein precursor RF_0466 38 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 67458655 Common - ATP-dependent RNA helicase RhlE RF_0263 208 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 67459177 Common fni isopentenyl pyrophosphate isomerase RF_0785 81 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 67458504 Common - hypothetical protein RF_0112 6 None None None 67458570 Common - hypothetical protein RF_0178 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 67459076 Common gabD Succinate semialdehyde dehydrogenase RF_0684 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 67459656 Common acnA aconitate hydratase RF_1264 223 COG1048 AcnA, Aconitase A Energy production and conversion 67458483 Common virB6_3 TrbL/VirB6 plasmid Conjugative transfer protein RF_0091 12 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 67459024 Common lspA lipoprotein signal peptidase RF_0632 191 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 67459281 Common - hypothetical protein RF_0889 17 None None None 67459412 Common pdhA Pyruvate dehydrogenase e1 component, alpha subunit precursor RF_1020 164 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 67459677 Common bolA2 BolA protein homolog RF_1285 47 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 67458983 Pathogen - Ankyrin repeat RF_0591 1 None None None 67459288 Common - Uncharacterized low-complexity protein RF_0896 75 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 67458716 Common def peptide deformylase RF_0324 210 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 67459068 Common - hypothetical protein RF_0676 152 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 67458851 Pathogen - hypothetical protein RF_0459 1 None None None 67459146 Common - hypothetical protein RF_0754 7 None None None 67459564 Common - tRNA/rRNA methyltransferase RF_1172 154 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 67458873 Common - hypothetical protein RF_0481 1 None None None 67459490 Common - hypothetical protein RF_1098 1 None None None 67459150 Common - hypothetical protein RF_0758 1 None None None 67459643 Common - hypothetical protein RF_1251 2 None None None 67458937 Common - hypothetical protein RF_0545 2 None None None 67458894 Common - hypothetical protein RF_0502 1 None None None 67459424 Common - hypothetical protein RF_1032 1 None None None 67458625 Common proP4 Proline/betaine transporter RF_0233 114 None None None 67459186 Common - hypothetical protein RF_0794 2 None None None 67459374 Common - hypothetical protein RF_0982 11 COG5595 COG5595, Zn-ribbon-containing, possibly nucleic-acid-binding protein General function prediction only 67459336 Common rpoZ DNA-directed RNA polymerase subunit omega RF_0944 69 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 67458823 Common - hypothetical protein RF_0431 10 None None None 67459199 Common lpdA2 dihydrolipoamide dehydrogenase RF_0807 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 67459168 Common - Acetyltransferase RF_0776 2 None None None 67458541 Common - ClpB protein RF_0149 213 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 67458662 Common ftsZ cell division protein FtsZ RF_0270 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 67458864 Common - hypothetical protein RF_0472 1 None None None 67459439 Common - hypothetical protein RF_1047 6 None None None 67459157 Common rho transcription termination factor Rho RF_0765 206 COG1158 Rho, Transcription termination factor Transcription 67458647 Common - hypothetical protein RF_0255 11 None None None 67459789 Common - Prophage antirepressor RF_1397 11 COG3617 COG3617, Prophage antirepressor Transcription 67459679 Common - Phage-related transcriptional regulator RF_1287 20 COG1476 COG1476, Predicted transcriptional regulators Transcription 67459230 Common - hypothetical protein RF_0838 2 None None None 67458727 Common relB1 DNA-damage-inducible protein J RF_0335 22 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 67459093 Common - Toxin of toxin-antitoxin system RF_0701 30 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 67459403 Common - hypothetical protein RF_1011 1 None None None 67459566 Common era GTP-binding protein Era RF_1174 232 COG1159 Era, GTPase General function prediction only 67459122 Common def2 Polypeptide deformylase RF_0730 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 67459513 Common omp1 Outer membrane protein omp1 RF_1121 161 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 67459671 Common - NT (nucleotidyltransferase) domain and HEPN (higher eukarytoes and prokaryotes nucleotide-binding) domain RF_1279 6 None None None 67459239 Common iscR Iron-sulfur cluster assembly transcription factor IscR RF_0847 156 COG1959 COG1959, Predicted transcriptional regulator Transcription 67458906 Common - hypothetical protein RF_0514 3 None None None 67459584 Pathogen - hypothetical protein RF_1192 1 None None None 67459246 Common nuoN1 NADH dehydrogenase subunit N RF_0854 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 67459074 Common - hypothetical protein RF_0682 1 None None None 67458660 Common ecoT ecotin precursor RF_0268 21 COG4574 Eco, Serine protease inhibitor ecotin General function prediction only 67459491 Common - Ankyrin repeat RF_1099 57 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 67459201 Common rnd Ribonuclease D RF_0809 114 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 67459632 Common - HicB family RF_1240 27 COG4226 HicB, Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters Function unknown 67459779 Common mutL DNA mismatch repair protein RF_1387 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 67458419 Common atpF F0F1 ATP synthase subunit B RF_0027 4 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 67458943 Common - Putative lyase RF_0551 17 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 67459131 Common bioY2 BioY family protein RF_0739 96 COG1268 BioY, Uncharacterized conserved protein General function prediction only 67458577 Common - hypothetical protein RF_0185 1 None None None 67459708 Common - Predicted transcriptional regulator RF_1316 26 COG3636 COG3636, Predicted transcriptional regulator Transcription 67459625 Common - Predicted permeases RF_1233 52 COG0795 COG0795, Predicted permeases General function prediction only 67459224 Common lysE Lysine efflux permease RF_0832 81 COG1279 COG1279, Lysine efflux permease General function prediction only 67458667 Common - tRNA/rRNA methyltransferase RF_0275 214 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 67459542 Common rplK 50S ribosomal protein L11 RF_1150 243 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 67459639 Common ampG3 AmpG protein RF_1247 108 None None None 67459694 Common - Outer memberane protein rOmpA RF_1302 10 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 67459054 Common dsbA Thiol:disulfide interchange protein DsbA RF_0662 86 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 67458548 Common - hypothetical protein RF_0156 2 None None None 67458770 Common recG ATP-dependent DNA helicase RecG RF_0378 236 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 67458412 Common - ComEC/Rec2-related protein RF_0020 91 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 67458594 Common - hypothetical protein RF_0202 1 COG0789 SoxR, Predicted transcriptional regulators Transcription 67459344 Pathogen - hypothetical protein RF_0952 1 None None None 67458426 Common - hypothetical protein RF_0034 42 COG4797 COG4797, Predicted regulatory domain of a methyltransferase General function prediction only 67458884 Common tolB translocation protein TolB RF_0492 152 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 67459654 Common nuoG NADH dehydrogenase subunit G RF_1262 189 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 67459361 Pathogen - Acetyltransferase RF_0969 1 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 67458890 Common hisS histidyl-tRNA synthetase RF_0498 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67459680 Common - hypothetical protein RF_1288 5 COG1633 COG1633, Uncharacterized conserved protein Function unknown 67458613 Common - Putative oxidoreductase protein RF_0221 138 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 67459394 Common - hypothetical protein RF_1002 50 COG4804 COG4804, Uncharacterized conserved protein Function unknown 67458673 Common rplB 50S ribosomal protein L2 RF_0281 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 67458481 Common virB6_1 TrbL/VirB6 plasmid Conjugative transfer protein RF_0089 7 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 67459273 Common - Transposase RF_0881 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459556 Common - hypothetical protein RF_1164 110 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 67459781 Common - Oxidoreductase RF_1389 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 67459712 Common - Cation diffusion facilitator family transporter RF_1320 189 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 67459537 Common rpoC DNA-directed RNA polymerase subunit beta' RF_1145 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 67459454 Common hscB co-chaperone HscB RF_1062 51 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 67459384 Common - hypothetical protein RF_0992 2 None None None 67458840 Common - hypothetical protein RF_0448 1 None None None 67458585 Common - hypothetical protein RF_0193 61 COG3943 COG3943, Virulence protein General function prediction only 67458914 Common cyaY frataxin-like protein RF_0522 27 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 67458537 Common aco1 Acyl-CoA desaturase 1 RF_0145 67 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 67458777 Common - hypothetical protein RF_0385 9 COG4692 COG4692, Predicted neuraminidase (sialidase) Carbohydrate transport and metabolism 67459483 Common - Thermostable carboxypeptidase RF_1091 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 67458980 Common - Transposase RF_0588 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459662 Common lpdA1 dihydrolipoamide dehydrogenase RF_1270 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 67459727 Common - hypothetical protein RF_1335 1 None None None 67458566 Common - ATP-dependent helicase RF_0174 229 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 67459080 Common - hypothetical protein RF_0688 2 None None None 67459714 Common - hypothetical protein RF_1322 115 COG1881 COG1881, Phospholipid-binding protein General function prediction only 67458714 Common - Transporter RF_0322 53 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 67459516 Common emrB Multidrug resistance protein B RF_1124 188 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67458402 Common - hypothetical protein RF_0010 1 None None None 67459591 Common rpmA 50S ribosomal protein L27 RF_1199 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 67458786 Common - Major facilitator family transporter RF_0394 1 None None None 67458435 Common - Sco2 protein precursor RF_0043 85 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 67458525 Common lgt prolipoprotein diacylglyceryl transferase RF_0133 208 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 67458831 Common - MFS type sugar transporter RF_0439 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67458836 Common - TPR repeats RF_0444 37 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 67459266 Common - hypothetical protein RF_0874 5 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 67458397 Common gltD putative bifunctional glutamate synthase subunit beta/2-polyprenylphenol hydroxylase RF_0005 119 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 67459602 Common - hypothetical protein RF_1210 2 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 67458519 Common - Tellurite resistance protein-related protein RF_0127 63 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 67458553 Common tlc5 ADP,ATP carrier protein RF_0161 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 67459217 Common plsC 1-acyl-sn-glycerol-3-phosphate acyltransferase RF_0825 155 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 67459152 Common infC translation initiation factor IF-3 RF_0760 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 67459102 Common nrdF ribonucleotide-diphosphate reductase subunit beta RF_0710 158 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 67459192 Common rpmJ 50S ribosomal protein L36 RF_0800 12 None None None 67458799 Common - Glycosyltransferase RF_0407 130 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 67459323 Common - Transposase RF_0931 53 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458976 Common tme malic enzyme RF_0584 208 COG0281 SfcA, Malic enzyme Energy production and conversion 67458828 Common - Transposase RF_0436 42 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459116 Common tlc4 ADP,ATP carrier protein RF_0724 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 67459736 Common trmB bifunctional N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase/tRNA (m7G46) methyltransferase RF_1344 227 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 67459442 Common pleD response regulator PleD RF_1050 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 67459745 Common alaS alanyl-tRNA synthetase RF_1353 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67459334 Common prsA Protein export protein PrsA precursor RF_0942 160 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 67459772 Pathogen - hypothetical protein RF_1380 1 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 67458933 Common - hypothetical protein RF_0541 1 None None None 67459553 Common sdhD Succinate dehydrogenase hydrophobic membrane anchor protein RF_1161 31 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 67458709 Pathogen - hypothetical protein RF_0317 1 None None None 67459427 Common ddl D-alanine--D-alanine ligase RF_1035 213 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 67459522 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B RF_1130 212 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 67458892 Common - ABC transporter ATP-binding protein RF_0500 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 67459268 Common tlyA Hemolysin A RF_0876 130 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 67458819 Common ntrY Nitrogen regulation protein NtrY RF_0427 221 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 67458451 Common pntB NAD(p) transhydrogenase subunit beta RF_0059 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 67459004 Common - hypothetical protein RF_0612 62 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 67459570 Common nuoF NADH dehydrogenase I chain F RF_1178 165 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 67459449 Common atm1 Multidrug resistance protein Atm1 RF_1057 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 67458604 Common bcr2 Bicyclomycin resistance protein RF_0212 119 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 67458899 Common - hypothetical protein RF_0507 31 None None None 67459682 Common sca13 Cell surface antigen-like protein Sca13 RF_1290 62 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 67458646 Common ostA Organic solvent tolerance protein homolog RF_0254 77 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 67459473 Pathogen - Ankyrin repeat RF_1081 1 None None None 67459073 Common trxB1 Thioredoxin reductase RF_0681 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 67459014 Common - hypothetical protein RF_0622 1 None None None 67458985 Common pyrG CTP synthetase RF_0593 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 67459195 Common mltE2 Putative soluble lytic murein transglycosylase RF_0803 43 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 67458887 Common - hypothetical protein RF_0495 2 None None None 67459756 Common dnaX DNA polymerase III subunits gamma and tau RF_1364 246 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 67459349 Common - Probable antitoxin of toxin-antitoxin system RF_0957 4 COG4710 COG4710, Predicted DNA-binding protein with an HTH domain General function prediction only 67459295 Common ftsL Cell division protein FtsL RF_0903 1 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 67459693 Common - Outer memberane protein rOmpA RF_1301 1 None None None 67459331 Common - Ankyrin repeat RF_0939 14 None None None 67458878 Common lacA ribose-5-phosphate isomerase B RF_0486 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 67459607 Common - hypothetical protein RF_1215 1 None None None 67459397 Common hspC1 Small heat shock protein RF_1005 47 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 67458788 Pathogen - hypothetical protein RF_0396 1 None None None 67458498 Common - Transposase RF_0106 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459310 Common - Type I site-specific restriction-modification system, R (restriction) subunit RF_0918 116 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 67459634 Common - S-adenosylmethionine synthetase MetK RF_1242 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 67458641 Common - hypothetical protein RF_0249 3 COG4095 COG4095, Uncharacterized conserved protein Function unknown 67459696 Common - Outer memberane protein rOmpA RF_1304 9 None None None 67459660 Common atpA F0F1 ATP synthase subunit alpha RF_1268 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 67458568 Common dnaQ DNA polymerase III subunit epsilon RF_0176 190 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 67459645 Common - hypothetical protein RF_1253 3 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 67458871 Common - hypothetical protein RF_0479 26 None None None 67459396 Common hspC2 Small heat shock protein RF_1004 133 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 67459531 Common - Transposase RF_1139 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459241 Common - hypothetical protein RF_0849 2 None None None 67458741 Common rplT 50S ribosomal protein L20 RF_0349 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 67459426 Common ftsQ Cell division protein FtsQ RF_1034 58 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 67458765 Common scoB Succinyl-CoA:3-ketoacid-coenzyme A transferase subunit B RF_0373 94 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 67459034 Common mfp Membrane-fusion protein component of the RND family transporter RF_0642 157 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 67459495 Common - Transposase RF_1103 21 COG5464 COG5464, Uncharacterized conserved protein Function unknown 67459769 Common - Type I restriction-modification system methyltransferase subunit RF_1377 104 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 67458610 Common rimJ Ribosomal-protein-alanine acetyltransferase RF_0218 91 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 67459673 Common - hypothetical protein RF_1281 14 None None None 67459184 Common - Probable toxin of toxin-antitoxin system RF_0792 50 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 67458442 Common - transposase/IS protein RF_0050 99 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 67459159 Common himD Integration host factor beta-subunit RF_0767 18 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 67459378 Common - hypothetical protein RF_0986 16 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 67459528 Common - hypothetical protein RF_1136 2 None None None 67459484 Common kgd alpha-ketoglutarate decarboxylase RF_1092 151 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 67458739 Common rnpA ribonuclease P RF_0347 1 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 67459253 Common - hypothetical protein RF_0861 1 None None None 67459066 Common - hypothetical protein RF_0674 1 None None None 67458561 Common - hypothetical protein RF_0169 7 None None None 67458677 Common rplP 50S ribosomal protein L16 RF_0285 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 162022122 Common pheS phenylalanyl-tRNA synthetase subunit alpha RF_0647 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 67458746 Common - Acetyltransferase RF_0354 27 COG0456 RimI, Acetyltransferases General function prediction only 67459286 Common - putative monovalent cation/H+ antiporter subunit F RF_0894 2 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 67459432 Common - hypothetical protein RF_1040 1 None None None 67459316 Common - Lysozyme RF_0924 3 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 67459097 Common - P pilus assembly protein FimD RF_0705 22 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 67459414 Common pbpE Penicillin-binding protein 4* RF_1022 114 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 67459226 Common ampG1 AmpG-related permease RF_0834 101 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 67459762 Common glnQ Glutamine ABC transporter ATP-binding protein RF_1370 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 67458748 Common - hypothetical protein RF_0356 2 None None None 67458487 Common vapC2 Toxin of toxin-antitoxin system RF_0095 55 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 67459148 Common - hypothetical protein RF_0756 1 None None None 67458592 Common - hypothetical protein RF_0200 5 None None None 67458882 Common - Probable toxin of toxin-antitoxin system RF_0490 12 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 67459791 Common hemH ferrochelatase RF_1399 176 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 67459050 Common ompR PetR protein RF_0658 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 67458826 Common - hypothetical protein RF_0434 1 None None None 67459535 Common pepA leucyl aminopeptidase RF_1143 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 67458506 Common - hypothetical protein RF_0114 1 None None None 67459548 Common yqiY Amino acid ABC transporter permease protein RF_1156 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 67458671 Common rplD 50S ribosomal protein L4 RF_0279 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 67459497 Common - Prolyl endopeptidase precursor RF_1105 64 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 67458508 Common - ParB-like partition proteins RF_0116 187 COG1475 Spo0J, Predicted transcriptional regulators Transcription 67458428 Common - Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C RF_0036 30 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 67458970 Common - hypothetical protein RF_0578 40 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 67459734 Common - hypothetical protein RF_1342 2 None None None 67459314 Common - Ankyrin repeat RF_0922 18 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 67458611 Common clpX ATP-dependent protease ATP-binding subunit RF_0219 231 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 67459275 Common - hypothetical protein RF_0883 5 COG5238 RNA1, Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport Signal transduction mechanisms / RNA processing and modification 67459452 Common uvrB excinuclease ABC subunit B RF_1060 231 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 67458922 Common topA DNA topoisomerase I RF_0530 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 67459284 Common - hypothetical protein RF_0892 1 None None None 67459613 Common recA recombinase A RF_1221 243 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 67458501 Common argS arginyl-tRNA synthetase RF_0109 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 67459783 Common - hypothetical protein RF_1391 2 None None None 67458767 Common - hypothetical protein RF_0375 2 None None None 67459506 Pathogen - hypothetical protein RF_1114 1 None None None 67459462 Common - hypothetical protein RF_1070 5 None None None 67459091 Common folD Methylenetetrahydrofolate dehydrogenase RF_0699 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 67458417 Common - hypothetical protein RF_0025 3 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 67458410 Common znuA Zinc/manganese ABC transporter substrate binding protein RF_0018 56 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 67458725 Common cydA Cytochrome d ubiquinol oxidase subunit I RF_0333 164 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 67459290 Common - Cytotoxic translational repressor of toxin-antitoxin system RelE RF_0898 21 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 67458991 Common folE GTP cyclohydrolase I RF_0599 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 67459586 Common - hypothetical protein RF_1194 210 COG0313 COG0313, Predicted methyltransferases General function prediction only 67459363 Common - Transposase RF_0971 21 None None None 162022118 Common acpP acyl carrier protein RF_1223 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 67459114 Common rpsO 30S ribosomal protein S15 RF_0722 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 67458779 Common - Transposase RF_0387 43 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67459237 Common iscS cysteine desulfurase RF_0845 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 67458905 Common pkcI Protein kinase C inhibitor 1 RF_0513 188 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 67458657 Common ampG2 AmpG protein RF_0265 98 None None None 67459404 Common ccmB Heme exporter protein B RF_1012 2 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 67459194 Pathogen - hypothetical protein RF_0802 1 None None None 67459248 Common hemB delta-aminolevulinic acid dehydratase RF_0856 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 67458432 Common - hypothetical protein RF_0040 2 None None None 67459580 Common glyA serine hydroxymethyltransferase RF_1188 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 67459203 Common gcvT Glycine cleavage T-protein RF_0811 95 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 67459587 Common - ABC-type transport systems periplasmic component RF_1195 17 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 67459138 Pathogen - hypothetical protein RF_0746 1 None None None 67459100 Common - Chitin binding domain RF_0708 4 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 67459575 Common - (Di)nucleoside polyphosphate hydrolase RF_1183 23 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 67459208 Common mccF2 Microcin C7 resistance protein RF_0816 73 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 67459022 Common tagD Glycerol-3-phosphate cytidyltransferase TagD RF_0630 123 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 67459175 Pathogen - Ankyrin repeat RF_0783 1 None None None 67459124 Common - Toxin of toxin-antitoxin system RF_0732 14 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 67458694 Common rpoA DNA-directed RNA polymerase subunit alpha RF_0302 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 67458463 Common - hypothetical protein RF_0071 2 None None None 67459609 Common - hypothetical protein RF_1217 145 None None None 67458433 Common - hypothetical protein RF_0041 7 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 67458802 Common spoT12 Guanosine polyphosphate pyrophosphohydrolase/synthetase homolog RF_0410 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 67459440 Common suhB Extragenic suppressor protein SuhB RF_1048 140 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 67459725 Common htpG heat shock protein 90 RF_1333 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 67459098 Common - P pilus assembly protein FimD RF_0706 36 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 67459041 Common dnaN DNA polymerase III subunit beta RF_0649 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 67458555 Common paaJ acetyl-CoA acetyltransferase RF_0163 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 67459722 Common - hypothetical protein RF_1330 3 COG5238 RNA1, Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport Signal transduction mechanisms / RNA processing and modification 67458834 Common - hypothetical protein RF_0442 1 None None None 67459321 Pathogen - hypothetical protein RF_0929 1 None None None 67458797 Common - hypothetical protein RF_0405 1 None None None 67459717 Common ssb single-strand DNA-binding protein RF_1325 198 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 67458515 Common dam Site-specific DNA adenine methylase RF_0123 100 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 67458517 Common - hypothetical protein RF_0125 1 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 67459264 Common nusA transcription elongation factor NusA RF_0872 216 COG0195 NusA, Transcription elongation factor Transcription 67459747 Common - hypothetical protein RF_1355 1 None None None 67459716 Common uvrA excinuclease ABC subunit A RF_1324 242 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 67458843 Common - MFS type sugar transporter RF_0451 1 None None None 67459306 Common - hypothetical protein RF_0914 25 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 67458982 Common mdh malate dehydrogenase RF_0590 191 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 67458912 Common - hypothetical protein RF_0520 1 None None None 67458448 Common czcR Transcriptional activator protein CzcR RF_0056 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 67458393 Common - hypothetical protein RF_0001 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 67459597 Common - Transposase RF_1205 53 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 67458467 Common - hypothetical protein RF_0075 8 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 67458806 Common ubiG 3-demethylubiquinone-9 3-methyltransferase RF_0414 148 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 67459684 Common infA translation initiation factor IF-1 RF_1292 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 67458583 Common tgt queuine tRNA-ribosyltransferase RF_0191 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 67458704 Common - hypothetical protein RF_0312 11 None None None 67458606 Common msbA2 Multidrug resistance protein RF_0214 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms