Vibrio fischeri ES114 chromosome I, complete sequence NC_006840 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 59711945 Common - transporter, LysE family VF1338 121 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 59711853 Common - outer membrane protease VF1246 11 COG4571 OmpT, Outer membrane protease Cell envelope biogenesis, outer membrane 59710671 Common - uroporphyrin-III C-methyltransferase VF0064 55 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 59712576 Common tgt queuine tRNA-ribosyltransferase VF1969 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 59712271 Common - transcriptional regulator, TetR family VF1664 23 COG1309 AcrR, Transcriptional regulator Transcription 59712128 Common - uridine phosphorylase VF1521 100 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 59711422 Common - replication initiation regulator SeqA VF0815 23 COG3057 SeqA, Negative regulator of replication initiationR DNA replication, recombination, and repair 59712921 Common - ribonuclease R VF2314 208 COG0557 VacB, Exoribonuclease R Transcription 59712984 Common - hypothetical protein VF2377 163 COG4147 DhlC, Predicted symporter General function prediction only 59711885 Common - GAF domain-containing proteins VF1278 80 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 59711397 Common - transmembrane regulatory protein ToxS VF0790 2 None None None 59713069 Common - 3'(2'),5'-bisphosphate nucleotidase VF2462 198 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 59712057 Common - DNA ligase VF1450 37 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 59712659 Common - Mg(2+) transporter MgtE VF2052 155 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 59711294 Common - D,D-heptose 1,7-bisphosphate phosphatase VF0687 132 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 59711467 Common - 3-oxoacyl-(acyl carrier protein) synthase II VF0860 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 59710901 Common - 3-isopropylmalate dehydrogenase VF0294 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 59711471 Common - hypothetical protein VF0864 151 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 59712322 Common - tetranactin resistance protein VF1715 140 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 59712671 Common - anaerobic C4-dicarboxylate transporter VF2064 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 59711413 Common - N-acetylglucosamine repressor VF0806 166 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 59710834 Common - MukF protein VF0227 49 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 59710714 Common - hypothetical protein VF0107 3 COG3223 COG3223, Predicted membrane protein Function unknown 59713007 Common - aspartate-semialdehyde dehydrogenase VF2400 226 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 59713085 Common - phosphoenolpyruvate carboxykinase VF2478 97 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 59711315 Common - sensor protein LuxQ VF0708 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59712346 Common acpP acyl carrier protein VF1739 179 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 59711460 Common - esterase VF0853 72 COG0824 FcbC, Predicted thioesterase General function prediction only 59712779 Common - ABC transporter ATP-binding protein VF2172 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 59711132 Common - sensor protein PhoQ VF0525 191 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59711429 Common sdhB succinate dehydrogenase iron-sulfur subunit VF0822 206 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 59711524 Common - hypothetical protein VF0917 106 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 59711838 Common - hypothetical protein VF1231 3 None None None 59710744 Common - phosphoglycerol transferase MdoB and related proteins, alkaline phosphatase superfamily VF0137 53 COG3083 COG3083, Predicted hydrolase of alkaline phosphatase superfamily General function prediction only 59713119 Common - hypothetical protein VF2512 2 None None None 59711143 Common alaS alanyl-tRNA synthetase VF0536 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59712413 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase VF1806 219 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 59712433 Common - chemotaxis protein CheW VF1826 137 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 59712420 Common - long-chain fatty acid transport protein precursor VF1813 79 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 59711437 Common - high-affinity zinc uptake system protein ZnuA precursor VF0830 168 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 59710808 Common - UDP-glucose 4-epimerase VF0201 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 59711851 Common - hypothetical protein VF1244 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 59712237 Common - Na(+)/H(+) antiporter VF1630 66 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 59710680 Common - hypothetical protein VF0073 84 COG1738 COG1738, Uncharacterized conserved protein Function unknown 59713164 Common ilvM acetolactate synthase 2 regulatory subunit VF2557 22 COG3978 COG3978, Acetolactate synthase (isozyme II), small (regulatory) subunit Function unknown 59713047 Common - Na(+) driven multidrug efflux pump VF2440 161 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 59713000 Common zntR zinc-responsive transcriptional regulator VF2393 150 COG0789 SoxR, Predicted transcriptional regulators Transcription 59712103 Common - glutaredoxin VF1496 94 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 59712234 Common - response regulator VF1627 218 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 59710801 Common - hypothetical protein VF0194 52 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 59712883 Common - cell division protein FtsN VF2276 13 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 59711187 Common - hypothetical membrane-spanning protein VF0580 52 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 59713019 Common - DNA-directed RNA polymerase subunit gamma VF2412 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 59712264 Common - oxidoreductase VF1657 54 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 59712288 Common - coniferyl aldehyde dehydrogenase VF1681 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 59711474 Common - hypothetical protein VF0867 1 None None None 59710741 Common - alpha-L-glycero-D-manno-heptose beta-1,4-glucosyltransferase VF0134 129 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 59712766 Common - serine protease VF2159 125 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 59712517 Common - ubiquinone biosynthesis protein AarF VF1910 12 None None None 59711643 Common - autoinducer regulatory protein AinR VF1036 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59711002 Common - toluene tolerance protein TTG2B VF0395 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 59711119 Common - hypothetical protein VF0512 2 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 59712315 Common - long-chain-fatty-acid--CoA ligase VF1708 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 59711803 Common - hypothetical protein VF1196 11 None None None 59711894 Common - methyltransferase VF1287 156 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 59711173 Common - ClpB protein VF0566 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 59711934 Common - transporter VF1327 41 COG4125 COG4125, Predicted membrane protein Function unknown 59712427 Common - cytochrome c-type biogenesis protein CcmE VF1820 93 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 59711161 Common tyrA bifunctional chorismate mutase/prephenate dehydrogenase VF0554 95 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 59712555 Common rnhB ribonuclease HII VF1948 239 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 59712097 Common cysB transcriptional regulator CysB VF1490 190 COG0583 LysR, Transcriptional regulator Transcription 59712384 Common - hypothetical protein VF1777 6 None None None 59711168 Common - chorismate mutase VF0561 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 59712859 Common - hypothetical protein VF2252 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 59712278 Common - 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase VF1671 96 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 59712521 Common - succinyl-diaminopimelate desuccinylase VF1914 209 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 59711182 Common - hypothetical protein VF0575 14 None None None 59711441 Common - ferrous iron transport protein B VF0834 202 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 59712592 Common - phosphate transport system permease protein PstC VF1985 221 COG4590 COG4590, ABC-type uncharacterized transport system, permease component General function prediction only 59710831 Common - hypothetical protein VF0224 32 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 59712493 Common - hypothetical protein VF1886 2 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 59710955 Common - sensor protein UhpB VF0348 17 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 59712083 Common - exoenzyme regulatory protein AepA precursor VF1476 104 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 59710722 Common envZ osmolarity sensor protein VF0115 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59712429 Common - heme chaperone heme-lyase VF1822 121 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 59711099 Common - putative protease YhbV precursor VF0492 49 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 59710695 Common - hypothetical cytosolic protein VF0088 36 COG3148 COG3148, Uncharacterized conserved protein Function unknown 59711029 Common - A/G-specific adenine DNA glycosylase VF0422 232 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 59712689 Common - hybrid sensory histidine kinase BarA VF2082 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59710717 Common - hypothetical protein VF0110 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 59711369 Common - hypothetical protein VF0762 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 59712408 Common - hypothetical protein VF1801 18 None None None 59710766 Common - hypothetical protein VF0159 4 None None None 59711623 Common hisH imidazole glycerol phosphate synthase subunit HisH VF1016 216 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 59711081 Common - D-alanyl-D-alanine carboxypeptidase/endopeptidase VF0474 93 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 59711360 Common leuS leucyl-tRNA synthetase VF0753 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59711576 Common - hypothetical protein VF0969 21 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 59710869 Common - DNA-directed RNA polymerase subunit alpha VF0262 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 59711387 Common - CopG protein VF0780 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 59712906 Common - DNA-binding transcriptional regulator OxyR VF2299 191 COG0583 LysR, Transcriptional regulator Transcription 59711691 Common - branched-chain amino acid transport system carrier protein VF1084 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 59711155 Common - signal recognition particle, subunit FFH/SRP54 VF0548 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 59711956 Common - hypothetical protein VF1349 134 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 59712245 Common - tRNA-dihydrouridine synthase VF1638 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 59711008 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase VF0401 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 59711633 Common - proton glutamate symport protein VF1026 165 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 59712819 Common - hypothetical protein VF2212 123 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 59712175 Common - ribosomal large subunit pseudouridine synthase F VF1568 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 59710894 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase VF0287 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 59712067 Common - transcriptional regulators, LysR family VF1460 66 COG0583 LysR, Transcriptional regulator Transcription 59710911 Common pgi glucose-6-phosphate isomerase VF0304 196 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 59710705 Common glnA glutamine synthetase VF0098 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 59712585 Common - accessory colonization factor AcfA-like protein VF1978 1 None None None 59711518 Common - inosine-guanosine kinase VF0911 65 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 59711933 Common - putative acetyltransferase in HXT11-HXT8 intergenic region VF1326 213 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 59711994 Common - 3-mercaptopyruvate sulfurtransferase VF1387 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 59710756 Common - glycosyltransferase VF0149 107 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 59710978 Common - hypothetical protein VF0371 9 None None None 59712258 Common - A-type carbonic anhydrase VF1651 52 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 59710820 Common - phosphoribulokinase VF0213 51 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 59712225 Common - methyl-accepting chemotaxis protein VF1618 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59712281 Common - oligopeptide-binding protein OppA VF1674 58 COG4533 COG4533, ABC-type uncharacterized transport system, periplasmic component General function prediction only 59711596 Common - sensory box/GGDEF family protein VF0989 188 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 59711656 Common - putative DNA methylase VF1049 85 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 59710664 Common - thioredoxin VF0057 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 59711040 Common - Holliday junction resolvase-like protein VF0433 111 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 59710619 Common gyrB DNA gyrase subunit B VF0012 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 59712042 Common - hypothetical protein VF1435 4 None None None 59711062 Common - DNA mismatch repair protein VF0455 30 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 59711211 Common - hypothetical protein VF0604 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 59710931 Common - hypothetical protein VF0324 8 None None None 59710971 Common - hypothetical protein VF0364 2 None None None 59711207 Common - hypothetical protein VF0600 13 COG5595 COG5595, Zn-ribbon-containing, possibly nucleic-acid-binding protein General function prediction only 59712164 Common - ATP-dependent helicase HrpA VF1557 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 59712242 Common - disulfide bond formation protein B VF1635 35 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 59711820 Common - hypothetical protein VF1213 30 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 59712771 Common - sugar fermentation stimulation protein A VF2164 106 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 59711842 Common pheS phenylalanyl-tRNA synthetase subunit alpha VF1235 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 59710924 Common - acetyltransferase VF0317 87 COG2153 ElaA, Predicted acyltransferase General function prediction only 59710992 Common - nitrogen regulatory IIA protein VF0385 134 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 59711515 Common - seryl-tRNA synthetase VF0908 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 59712680 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase VF2073 194 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 59712798 Common - zinc-binding protein VF2191 59 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 59711486 Common - multidrug resistance protein B VF0879 199 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 59711263 Common - transcription elongation factor VF0656 23 COG0782 GreA, Transcription elongation factor Transcription 59710940 Common - hypothetical outer membrane protein VF0333 98 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 59711878 Common - hypothetical membrane spanning protein VF1271 11 COG0730 COG0730, Predicted permeases General function prediction only 59713035 Common pssA phosphatidylserine synthase VF2428 44 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 59712513 Common - NapD protein VF1906 27 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 59711749 Common - hypothetical protein VF1142 21 COG3150 COG3150, Predicted esterase General function prediction only 59710685 Common - hypothetical protein VF0078 22 COG3078 COG3078, Uncharacterized protein conserved in bacteria Function unknown 59711234 Common - PilF protein VF0627 78 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 59712208 Common - peptidyl-prolyl cis-trans isomerase VF1601 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 59711547 Common moaA molybdenum cofactor biosynthesis protein A VF0940 203 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 59712012 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A VF1405 101 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 59711346 Common frsA fermentation/respiration switch protein VF0739 25 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 59711911 Common - copper-exporting ATPase VF1304 192 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 59711092 Common nusA transcription elongation factor NusA VF0485 218 COG0195 NusA, Transcription elongation factor Transcription 59712823 Common sspA stringent starvation protein A VF2216 103 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 59711771 Common - export ABC transporter permease protein VF1164 148 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 59713101 Common - thiol:disulfide interchange protein DsbD VF2494 152 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 59712874 Common - cystathionine gamma-synthase VF2267 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 59711849 Common - phosphoenolpyruvate synthase VF1242 174 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 59710827 Common - glutathione-regulated potassium-efflux system protein KefB VF0220 126 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 59711225 Common - scaffold protein VF0618 151 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 59712636 Nonpathogen - hypothetical protein VF2029 1 None None None 59711871 Common - chlorohydrolase/deaminase family protein VF1264 183 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 59711976 Common - methyl-accepting chemotaxis protein VF1369 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59712485 Common - pili chemotaxis protein methyltransferase CheR homolog PilK VF1878 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 59712464 Common - transcriptional regulatory protein VF1857 2 None None None 59712021 Common - riboflavin synthase subunit alpha VF1414 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 59712457 Common fliH flagellar assembly protein H VF1850 57 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 161986799 Common metN DL-methionine transporter ATP-binding subunit VF0686 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 59711542 Common - Na(+)-translocating NADH-quinone reductase subunit E VF0935 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 59711654 Nonpathogen - hypothetical protein VF1047 1 None None None 59711876 Common - DNA polymerase V subunit VF1269 65 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 59712786 Common aceF dihydrolipoamide acetyltransferase VF2179 196 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 59711967 Common - formate dehydrogenase (cytochrome b) major subunit VF1360 190 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 59711236 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase VF0629 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 59711246 Common - aminobenzoyl-glutamate transport protein VF0639 39 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 59712657 Common - putative cyclomaltodextrinase VF2050 56 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 59713001 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase VF2394 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 59712889 Common - succinylglutamic semialdehyde dehydrogenase VF2282 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 59711323 Common - thiamine biosynthesis protein ThiI VF0716 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 59712145 Common - hypothetical protein VF1538 4 None None None 59713013 Common - curli production assembly/transport component CsgF precursor VF2406 10 None None None 59711600 Common - IcmF-related protein VF0993 46 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 59711350 Common lipB lipoyltransferase VF0743 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 59711435 Common - high-affinity zinc uptake system membrane protein ZnuB VF0828 180 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 59711537 Common - SoxR-reducing system protein RsxE VF0930 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 59711024 Common - hypothetical protein VF0417 5 None None None 59711829 Common - hemin-binding periplasmic protein HmuT precursor VF1222 111 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 59712390 Common - anaerobic nitric oxide reductase transcription regulator VF1783 169 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 59711255 Common - glutathione-dependent formaldehyde dehydrogenase VF0648 194 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 59712036 Nonpathogen - hypothetical protein VF1429 5 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 59711141 Common - DNA mismatch repair protein VF0534 205 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 59711587 Common - transporter, MFS superfamily VF0980 54 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 59711920 Common - BAX protein VF1313 31 COG2992 Bax, Uncharacterized FlgJ-related protein General function prediction only 59712989 Common - DNA polymerase III subunit epsilon VF2382 55 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 59710608 Common - flavodoxin VF0001 72 COG0716 FldA, Flavodoxins Energy production and conversion 59712081 Common - putative exonuclease VF1474 23 None None None 59710854 Nonpathogen - LSU ribosomal protein L14P VF0247 1 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 59712530 Common - arsenate reductase family protein VF1923 111 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 59712503 Common - phosphoenolpyruvate-protein phosphotransferase VF1896 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 59711193 Common - hypothetical protein VF0586 2 None None None 59711755 Common - putative two-component response-regulatory protein YehT VF1148 208 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 59711260 Common - 23S rRNA methyltransferase VF0653 22 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 59711609 Common - hypothetical protein VF1002 14 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 59712374 Common - cold shock protein VF1767 178 COG1278 CspC, Cold shock proteins Transcription 59711777 Common - hypothetical protein VF1170 7 None None None 59712470 Common - flagellin VF1863 125 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 59711019 Common - DNA polymerase III subunit chi VF0412 33 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 59711204 Common - hypothetical protein VF0597 6 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 59713032 Common - biotin--protein ligase VF2425 225 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 59711751 Common - putative ATP-dependent RNA helicase RhlE VF1144 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 59710612 Common rpmH 50S ribosomal protein L34 VF0005 199 None None None 59712357 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase VF1750 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 59711357 Common - iojap protein family VF0750 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 59712590 Common - phosphate transport ATP-binding protein PstB VF1983 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 59711071 Common - SSU ribosomal protein S20P VF0464 58 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 59712895 Common - ribulose-phosphate 3-epimerase VF2288 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 59712945 Common - elongation factor P VF2338 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 59710697 Common - 2-dehydro-3-deoxyphosphogluconate aldolase VF0090 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 59711049 Common pgk phosphoglycerate kinase VF0442 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 59710763 Common - WbfB protein VF0156 22 None None None 59712992 Common - 3-dehydroquinate dehydratase VF2385 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 59710999 Common - arabinose-5-phosphate isomerase VF0392 169 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 59711797 Common - hypothetical protein VF1190 36 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 59710779 Common - O-acetyltransferase VF0172 114 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 59710707 Common rbn ribonuclease BN VF0100 136 COG1295 Rbn, Predicted membrane protein Function unknown 59712410 Common - Mg(2+) transport ATPase protein C VF1803 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 59711115 Common - SMP protein precursor VF0508 16 COG3726 AhpA, Uncharacterized membrane protein affecting hemolysin expression General function prediction only 59712627 Common - putative phage tail protein VF2020 7 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 59712177 Common - DNA-binding response regulator in two-component regulatory system with TorS VF1570 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 59712812 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase VF2205 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 59711520 Common - glyceraldehyde-3-phosphate dehydrogenase VF0913 221 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 59713027 Common - transcription antitermination protein NusG VF2420 207 COG0250 NusG, Transcription antiterminator Transcription 59712161 Common nrfA cytochrome c nitrite reductase VF1554 40 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 59712511 Common - cytochrome c-type protein NapB VF1904 41 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 59712479 Common flgG flagellar basal body rod protein FlgG VF1872 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 59710918 Common - sulfite reductase [NADPH] hemoprotein beta-component VF0311 141 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 59711572 Common - quinolinate synthetase VF0965 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 59711805 Common - putative competence-damage protein VF1198 162 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 59713071 Common - general secretion pathway protein N VF2464 9 None None None 59712951 Common cpxA two-component sensor protein VF2344 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59713092 Common - diaminopimelate decarboxylase VF2485 219 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 59712227 Common - periplasmic sensory protein associated with the TorRS two-component regulatory system VF1620 14 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 59711054 Common - flavodoxin FldB VF0447 67 COG0716 FldA, Flavodoxins Energy production and conversion 59713148 Common - DNA processing protein VF2541 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 59712253 Common - malate-2H+/lactate-NA+ antiporter VF1646 52 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 59710770 Common - hypothetical protein VF0163 28 None None None 59710896 Common - organic solvent tolerance protein VF0289 125 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 59711769 Common - outer membrane protein TolC VF1162 70 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 59712193 Common - histidine transport system permease protein HisQ VF1586 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 59711456 Common - AMP-(fatty)acid ligase VF0849 65 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 59711278 Common - urease accessory protein UreF VF0671 72 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 59712397 Common - ATP-dependent RNA helicase VF1790 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 59712869 Common - acetolactate synthase III small subunit VF2262 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 59711406 Common - DNA-binding protein HU VF0799 209 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 59712738 Common - cell wall endopeptidase, family M23/M37 VF2131 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 59711430 Common kgd alpha-ketoglutarate decarboxylase VF0823 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 59711714 Common - ABC transporter ATP-binding protein VF1107 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 59712755 Common - phosphoglucomutase VF2148 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 59711734 Nonpathogen - hypothetical protein VF1127 3 None None None 59711088 Common - phosphoglucosamine mutase VF0481 240 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 59713137 Nonpathogen - hypothetical protein VF2530 1 None None None 59710632 Common fadB multifunctional fatty acid oxidation complex subunit alpha VF0025 187 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 59712975 Common - high-affinity zinc uptake system membrane protein ZnuB VF2368 159 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 59710653 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase VF0046 221 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 59712638 Common - hypothetical protein VF2031 3 None None None 59712972 Common - high-affinity zinc uptake system protein ZnuA precursor VF2365 41 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 59712843 Common - methyl-accepting chemotaxis protein VF2236 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711683 Common - sulfite-dehydrogenase VF1076 66 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 59713173 Common - F0F1 ATP synthase subunit alpha VF2566 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 59712703 Common - hypothetical protein VF2096 50 COG2938 COG2938, Uncharacterized conserved protein Function unknown 59712157 Common - heme chaperone--apocytochrome heme-lyase VF1550 118 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 59712007 Common - C4-dicarboxylate transport sensor protein DctB VF1400 206 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 59710928 Common cysN sulfate adenylyltransferase subunit 1 VF0321 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 59712836 Common - esterase YqiA VF2229 47 COG3150 COG3150, Predicted esterase General function prediction only 59711619 Common hisG ATP phosphoribosyltransferase VF1012 213 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 59712851 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase VF2244 188 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 59711817 Common - sporulation-control protein VF1210 20 COG4326 Spo0M, Sporulation control protein General function prediction only 59712600 Common - chaperone protein DnaJ VF1993 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 59712730 Common - Fe-S oxidoreductase VF2123 107 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 59713155 Common - hypothetical protein VF2548 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 59711404 Common clpX ATP-dependent protease ATP-binding subunit VF0797 230 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 59711245 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein VF0638 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 59711918 Common - tRNA s2C32 biosynthesis protein TtcA VF1311 167 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 59712912 Common - acetylglutamate kinase VF2305 205 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 59711377 Common - transcriptional regulator VF0770 33 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 59712717 Common - Na(+)-linked D-alanine glycine permease VF2110 115 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 59710877 Common - ATP-dependent helicase HepA VF0270 126 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 59712805 Common - cell division protein FtsQ VF2198 41 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 59712180 Common - DNA transformation protein TfoX VF1573 44 COG3070 TfoX, Regulator of competence-specific genes Transcription 59712219 Common - phosphate transport system permease protein PstA VF1612 226 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 59712338 Common - stringent starvation protein A VF1731 24 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 59711663 Common - phosphoglucomutase VF1056 234 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 59712207 Common cysS cysteinyl-tRNA synthetase VF1600 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59711226 Common - HesB protein family VF0619 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 59711125 Common - bipartite nuclear localization signal containing protein, similar to TadC VF0518 64 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 59711868 Common - lactoylglutathione lyase family protein VF1261 43 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 59710917 Common - sulfite reductase [NADPH] flavoprotein alpha-component VF0310 103 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 59711104 Common - hypothetical protein VF0497 2 None None None 59710673 Common hemC porphobilinogen deaminase VF0066 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 59710870 Common rplQ 50S ribosomal protein L17 VF0263 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 59712187 Common - queuosine biosynthesis protein QueC VF1580 176 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 59710811 Common groES co-chaperonin GroES VF0204 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 59710967 Common - general secretion pathway protein A VF0360 69 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 59711981 Common - regulator of kinase autophosphorylation inhibitor VF1374 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 59712360 Common - iron-sulfur cluster assembly/repair protein ApbC VF1753 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 59712524 Common - lipoprotein VF1917 25 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 59711366 Common - tRNA 2-methylthioadenosine synthase VF0759 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 59712367 Common cmk cytidylate kinase VF1760 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 59710840 Common tuf elongation factor Tu VF0233 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 59712137 Common - transcriptional regulator, GntR family VF1530 91 COG2188 PhnF, Transcriptional regulators Transcription 59712641 Common - hypothetical protein VF2034 1 None None None 59711641 Common - PHP domain containing protein (TRPH) VF1034 132 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 59711724 Common - toxin corregulated pilus biosynthesis protein I VF1117 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59710847 Common rpsS 30S ribosomal protein S19 VF0240 244 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 59711613 Common - hypothetical protein VF1006 16 None None None 59712860 Common - DNA primase VF2253 200 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 59711986 Common - hypothetical protein VF1379 2 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 59713024 Common - 50S ribosomal protein L1 VF2417 216 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 59710623 Common glyS glycyl-tRNA synthetase subunit beta VF0016 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 59712075 Common - hypothetical protein VF1468 2 None None None 59711212 Common - 6-phospho-beta-glucosidase VF0605 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 59711711 Common - hypothetical protein VF1104 24 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 59712595 Common - phosphate regulon transcriptional regulatory protein PhoB VF1988 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 59713149 Common - putative peptidoglycan binding domain VF2542 46 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 59712356 Common - sulfate transporter VF1749 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 59711810 Common - 3-demethylubiquinone-9 3-methyltransferase VF1203 179 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 59710639 Common - thiamine biosynthesis protein ThiC VF0032 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 59710987 Common - hypothetical protein VF0380 62 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 59712710 Common - hypothetical protein VF2103 35 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 59712389 Common - anaerobic nitric oxide reductase flavorubredoxin VF1782 115 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 59712298 Common - amidophosphoribosyltransferase VF1691 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 59712676 Common pcm protein-L-isoaspartate O-methyltransferase VF2069 158 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 59711309 Common - 3,4-dihydroxy-2-butanone-4-phosphate synthase VF0702 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 59712678 Common truD tRNA pseudouridine synthase D VF2071 87 COG0585 COG0585, Uncharacterized conserved protein Function unknown 59710790 Common - CDP-glucose 4,6-dehydratase VF0183 167 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 59711696 Common - immunogenic protein VF1089 85 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 59711562 Common - protein YbgT VF0955 22 COG4890 COG4890, Predicted outer membrane lipoprotein Function unknown 59712436 Common - chromosome partitioning protein ParA VF1829 201 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 59712396 Common - methyl-accepting chemotaxis protein VF1789 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711185 Common - alternative oxidase VF0578 12 None None None 59710736 Common - hypothetical protein VF0129 2 None None None 59712495 Common - hypothetical protein VF1888 1 None None None 59711180 Common - chromate transport protein VF0573 115 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 59712069 Common - hypothetical protein VF1462 4 None None None 59712256 Common - hypothetical protein VF1649 21 COG3082 COG3082, Uncharacterized protein conserved in bacteria Function unknown 59712197 Common - formate acetyltransferase VF1590 58 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 59713012 Common - curli production assembly/transport component CsgG precursor VF2405 14 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 59711533 Common - sodium-type flagellar protein MotY precursor VF0926 122 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 59710902 Common - 2-isopropylmalate synthase VF0295 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 59711373 Common lolB outer membrane lipoprotein LolB VF0766 48 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 59711880 Common - hypothetical protein VF1273 10 COG2966 COG2966, Uncharacterized conserved protein Function unknown 59710789 Common - glucose-1-phosphate cytidylyltransferase VF0182 163 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 59710720 Common - chromosome partitioning protein ParA VF0113 63 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 59712291 Common - integral membrane protein (rhomboid family) VF1684 15 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 59711705 Common - peptidyl-prolyl cis-trans isomerase VF1098 198 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 59711446 Common argS arginyl-tRNA synthetase VF0839 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59711569 Common tolB translocation protein TolB VF0962 151 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 59710947 Common - probable transcriptional regulator SyrB VF0340 14 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 59712095 Common - aromatic amino acid aminotransferase VF1488 74 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 59711465 Common - putative beta-hydroxydecanoyl-ACP dehydrase VF0858 24 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 59712562 Common - membrane metalloprotease VF1955 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 161986796 Common upp uracil phosphoribosyltransferase VF1927 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 59712958 Common - cell wall endopeptidase, family M23/M37 VF2351 186 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 59710683 Common - cytochrome c4 VF0076 63 COG2863 COG2863, Cytochrome c553 Energy production and conversion 59712573 Common secF preprotein translocase subunit SecF VF1966 218 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 59711166 Common - Trp operon repressor VF0559 23 COG2973 TrpR, Trp operon repressor Transcription 59712085 Common - hypothetical protein VF1478 1 None None None 59710803 Common - undecaprenyl-phosphate beta-N-acetyl-D-fucosaminephosphotransferase VF0196 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 59710729 Common - lipid A biosynthesis lauroyl acyltransferase VF0122 90 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 59711730 Common - hypothetical protein VF1123 13 None None None 59712093 Common - hypothetical protein VF1486 73 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 59710957 Common - putative capsule polysaccharide export protein precursor VF0350 108 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 59710980 Common - rod shape-determining protein MreC VF0373 157 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 59712898 Common aroB 3-dehydroquinate synthase VF2291 206 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 59712611 Common - hypothetical protein VF2004 13 None None None 59712044 Common - hypothetical protein VF1437 3 None None None 59710734 Common rpmB 50S ribosomal protein L28 VF0127 164 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 59713179 Common - chromosome partitioning protein ParB VF2572 178 COG1475 Spo0J, Predicted transcriptional regulators Transcription 59710815 Common - hypothetical protein VF0208 3 None None None 59712546 Common - membrane-bound lytic murein transglycosylase D precursor VF1939 124 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 59713059 Common - cell division ATP-binding protein FtsE VF2452 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 59712706 Common - hypothetical protein VF2099 14 None None None 59712634 Common - hypothetical protein VF2027 7 COG4228 COG4228, Mu-like prophage DNA circulation protein General function prediction only 59712111 Common - methyl-accepting chemotaxis protein VF1504 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711083 Common greA transcription elongation factor GreA VF0476 204 COG0782 GreA, Transcription elongation factor Transcription 59711685 Common - hypothetical protein VF1078 12 COG4954 COG4954, Uncharacterized protein conserved in bacteria Function unknown 59712324 Common - transporter, drug/metabolite exporter family VF1717 137 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 59711740 Common - methyl-accepting chemotaxis protein VF1133 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711943 Nonpathogen - hypothetical protein VF1336 1 None None None 59712239 Common - hypothetical outer membrane protein VF1632 23 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 59711153 Common - magnesium and cobalt efflux protein CorB VF0546 218 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 59713040 Common - glutamate racemase VF2433 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 59712213 Common cls cardiolipin synthetase VF1606 152 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 59711836 Common - VgrG protein VF1229 65 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 59710651 Common - RmuC family protein VF0044 87 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 59712283 Common - hypothetical protein VF1676 17 COG1309 AcrR, Transcriptional regulator Transcription 59713169 Common glmU bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase VF2562 234 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 59713111 Common - hypothetical cytosolic protein VF2504 11 None None None 59712415 Common - phosphohistidine phosphatase SixA VF1808 54 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 59711424 Common - NIF3-related protein VF0817 130 COG0327 COG0327, Uncharacterized conserved protein Function unknown 59710743 Common - 3-deoxy-D-manno-octulosonic-acid kinase VF0136 20 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 59711145 Common - carbon storage regulator VF0538 80 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 59711887 Common - carboxy-terminal protease VF1280 184 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 59713060 Common - cell division protein FtsY VF2453 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 59713118 Nonpathogen - hypothetical protein VF2511 1 None None None 59711551 Common - glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) VF0944 18 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 59712539 Common fadE acyl-CoA dehydrogenase VF1932 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 59712961 Common - anaerobic C4-dicarboxylate transporter VF2354 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 59712451 Common fliN flagellar motor switch protein VF1844 121 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 59713151 Common fmt methionyl-tRNA formyltransferase VF2544 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 59711415 Common - hypothetical protein VF0808 52 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 59712487 Common flgA flagellar basal body P-ring biosynthesis protein FlgA VF1880 45 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 59712201 Common oppD oligopeptide transporter ATP-binding component VF1594 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 59712885 Common hslU ATP-dependent protease ATP-binding subunit VF2278 214 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 59710922 Common - opacity associated proteins OapA VF0315 15 COG3061 OapA, Cell envelope opacity-associated protein A Cell envelope biogenesis, outer membrane 59710676 Common - chloramphenicol-sensitive protein RarD VF0069 97 COG2962 RarD, Predicted permeases General function prediction only 59713103 Common - serine/threonine protein kinase VF2496 148 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 59711050 Common - fructose-bisphosphate aldolase VF0443 138 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 59712266 Common - hypothetical protein VF1659 6 None None None 59710616 Common dnaA chromosomal replication initiation protein VF0009 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 59712222 Common - hypothetical protein VF1615 1 None None None 59710666 Common - hypothetical protein VF0059 3 None None None 59711439 Common - hypothetical protein VF0832 81 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 59712125 Common - heat shock protein 70 VF1518 209 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 59712319 Common - glycoprotease protein family VF1712 205 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 59711064 Common - fused phosphoenolpyruvate-protein phosphotransferase PtsP/GAF domain VF0457 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 59711590 Nonpathogen - hypothetical protein VF0983 2 COG3042 Hlx, Putative hemolysin General function prediction only 59712777 Common panC pantoate--beta-alanine ligase VF2170 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 59711488 Common - bicyclomycin/multidrug efflux system VF0881 216 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 59712362 Common - orotidine 5'-phosphate decarboxylase VF1755 170 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 59710862 Common rpmD 50S ribosomal protein L30 VF0255 128 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 59711985 Common - transcriptional regulators, LysR family VF1378 192 COG0583 LysR, Transcriptional regulator Transcription 59710624 Common - alpha-amylase VF0017 110 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 59710990 Common - phosphocarrier protein HPr VF0383 126 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 59710933 Common - permease VF0326 32 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 59712821 Common - 21 kDa hemolysin precursor VF2214 63 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 59711548 Common moaC molybdenum cofactor biosynthesis protein C VF0941 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 59713037 Nonpathogen - hypothetical protein VF2430 1 None None None 59710702 Common - nitrogen regulation protein NR(I) VF0095 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 59712170 Common - hypothetical protein VF1563 1 None None None 59713017 Common - CsgA-like protein VF2410 11 None None None 59712133 Common - hypothetical protein VF1526 10 None None None 59712166 Common - hypothetical protein VF1559 9 None None None 59711451 Common - hypothetical protein VF0844 32 None None None 59712026 Common - transcriptional regulators, LysR family VF1419 151 COG0583 LysR, Transcriptional regulator Transcription 59712210 Common - sensory box/GGDEF family protein VF1603 63 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 59712369 Common aat leucyl/phenylalanyl-tRNA--protein transferase VF1762 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 59712792 Common - pilin subunit PilA VF2185 94 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 59712013 Common - molybdopterin biosynthesis MoeA protein VF1406 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 59711861 Common - Na(+)/H(+) antiporter NhaC VF1254 48 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 59710825 Common - ABC transporter ATP-binding protein VF0218 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 59711598 Common - protein phosphatase 2C VF0991 131 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 59712691 Common - pyridoxal phosphate biosynthetic protein PdxJ VF2084 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 59711494 Common nhaA pH-dependent sodium/proton antiporter VF0887 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 59710977 Common - hypothetical protein VF0370 6 None None None 59711232 Common ndk nucleoside diphosphate kinase VF0625 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 59712907 Common - glutaredoxin VF2300 116 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 59713029 Common secE preprotein translocase subunit SecE VF2422 60 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 59712740 Common - periplasmic component of efflux system VF2133 166 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 59711625 Common - imidazole glycerol phosphate synthase subunit HisF VF1018 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 59711827 Common - hemin transport system ATP-binding protein HmuV VF1220 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 59711269 Common - hypothetical protein VF0662 12 None None None 59711743 Common - hypothetical protein VF1136 11 COG5633 COG5633, Predicted periplasmic lipoprotein General function prediction only 59712468 Common - flagellar protein FlaG VF1861 20 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 59711332 Common - Na(+)-translocating NADH-quinone reductase subunit A VF0725 39 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 59711692 Common - hypothetical protein VF1085 4 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 59711620 Common hisD histidinol dehydrogenase VF1013 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 59711218 Common - hypothetical protein VF0611 10 None None None 59711362 Common lnt apolipoprotein N-acyltransferase VF0755 166 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 59711316 Common - hypothetical protein VF0709 7 None None None 59711426 Common sdhC succinate dehydrogenase cytochrome b556 large membrane subunit VF0819 75 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 59712727 Common - DNA-binding response regulator in two-component regulatory system with ArcB or CpxA VF2120 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 59712455 Common fliJ flagellar biosynthesis chaperone VF1848 37 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 59711030 Common - glutaminase VF0423 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 59712791 Common - quinolinate phosphoribosyltransferase VF2184 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 59713005 Common - CBS-domain containing protein VF2398 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 59711036 Common - pyrroline-5-carboxylate reductase VF0429 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 59711280 Common ureC urease subunit alpha VF0673 99 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 59710648 Common - chloramphenicol resistance protein VF0041 226 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 59710782 Common - glycosyltransferase VF0175 48 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 59712540 Common - acyl-CoA dehydrogenase VF1933 47 None None None 59712583 Common - copper homeostasis protein CutC VF1976 58 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 59710746 Common - ADP-heptose--LPS heptosyltransferase II VF0139 86 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 59712846 Common - hypothetical protein VF2239 38 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 59712947 Common pfkA 6-phosphofructokinase VF2340 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 59711954 Common - PhnA protein VF1347 104 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 59712309 Common - membrane-bound lytic murein transglycosylase B VF1702 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 59710908 Common - replicative DNA helicase VF0301 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 59713049 Common - LexA repressor VF2442 156 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 59713174 Common - F0F1 ATP synthase subunit delta VF2567 175 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 59712986 Common - sensory transduction protein kinase VF2379 219 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 59712863 Common - long-chain-fatty-acid--CoA ligase VF2256 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 59712720 Common - uracil-DNA glycosylase VF2113 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 59711066 Common - prolipoprotein diacylglyceryl transferase VF0459 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 59712240 Common - fatty acid metabolism regulator VF1633 56 COG2186 FadR, Transcriptional regulators Transcription 59710764 Common - WbfB protein VF0157 14 None None None 59711556 Common aspS aspartyl-tRNA synthetase VF0949 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59712940 Common - lysyl-tRNA synthetase VF2333 225 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 59712422 Common - lipoprotein VF1815 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 59711385 Common ushA bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor VF0778 141 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 59712750 Common - chitooligosaccharide transport ATP-binding protein VF2143 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 59712400 Common - formate--tetrahydrofolate ligase VF1793 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 59711812 Common - hypothetical protein VF1205 8 None None None 59711199 Common - hypothetical protein VF0592 72 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 59711775 Common - exonuclease SbcC VF1168 135 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 59713097 Common - hypothetical protein VF2490 2 None None None 59711694 Common - hypothetical protein VF1087 1 None None None 59711607 Common - quinoprotein dehydrogenase VF1000 43 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 59712554 Common dnaE DNA polymerase III subunit alpha VF1947 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 59710610 Common - putative inner membrane protein translocase component YidC VF0003 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 59712725 Common thrA bifunctional aspartokinase I/homeserine dehydrogenase I VF2118 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 59712967 Common - glyceraldehyde-3-phosphate dehydrogenase VF2360 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 59711745 Common - TcpI, toxin-coregulated pilus biosynthesis gene VF1138 138 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711972 Common - hypothetical protein VF1365 7 None None None 59712980 Common - transcriptional regulator, DeoR family VF2373 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 59711192 Common - N-acetylglutamate synthase VF0585 201 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 59711202 Common - hypothetical protein VF0595 48 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 59710761 Common - hypothetical protein VF0154 29 None None None 59711639 Common - anthranilate synthase component II VF1032 233 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 59711800 Common - hypothetical protein VF1193 24 COG3490 COG3490, Uncharacterized protein conserved in bacteria Function unknown 59712994 Common - acetyl-CoA carboxylase biotin carboxylase subunit VF2387 232 COG0439 AccC, Biotin carboxylase Lipid metabolism 59710915 Common - hypothetical protein VF0308 12 None None None 59710906 Common - outer membrane protein VF0299 3 COG3137 COG3137, Putative salt-induced outer membrane protein Cell envelope biogenesis, outer membrane 59712526 Common - glycine cleavage system transcriptional repressor VF1919 34 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 59711117 Common - fimbrial protein precursor VF0510 1 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 59712614 Common - hypothetical protein VF2007 2 None None None 59711121 Nonpathogen - hypothetical protein VF0514 1 None None None 59712191 Common - glutaredoxin 2 VF1584 18 COG2999 GrxB, Glutaredoxin 2 Posttranslational modification, protein turnover, chaperones 59713073 Common - general secretion pathway protein L VF2466 19 COG3297 PulL, Type II secretory pathway, component PulL Intracellular trafficking and secretion 59712902 Common - pili assembly protein PilO VF2295 42 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 59710856 Common rplE 50S ribosomal protein L5 VF0249 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 59712629 Common - phage protein VF2022 20 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 59711395 Common - cell division inhibitor VF0788 106 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 59712376 Common - hypothetical protein VF1769 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 59712340 Common - putative deoxyribonuclease YcfH VF1733 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 59712387 Common - ferredoxin--NADP reductase VF1780 102 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 59711068 Common - sodium-dependent phosphate transporter VF0461 23 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 59711792 Common - hypothetical protein VF1185 14 None None None 59712505 Common - melanin biosynthesis protein TyrA VF1898 61 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 59712662 Common - cytochrome c peroxidase VF2055 95 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 59711661 Common - hypothetical protein VF1054 35 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 59711767 Common - queuosine biosynthesis protein QueD VF1160 120 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 59713094 Common - oligopeptidase A VF2487 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 59712023 Common - tetratricopeptide repeat family protein VF1416 16 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 59711238 Common - hypothetical protein VF0631 63 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 59711301 Common - hypothetical membrane spanning protein VF0694 48 COG1284 COG1284, Uncharacterized conserved protein Function unknown 59712938 Common - phosphatidylserine decarboxylase VF2331 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 59712563 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase VF1956 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 59712655 Common - amylo-1,6-glucosidase VF2048 42 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 59711076 Common - peptidyl-prolyl cis-trans isomerase VF0469 126 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 59711736 Common - hypothetical protein VF1129 8 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 59711588 Nonpathogen - alternative oxidase 2 precursor VF0981 3 None None None 59711674 Common - transporter VF1067 50 COG2259 COG2259, Predicted membrane protein Function unknown 59711539 Common - electron transport complex protein RnfD VF0932 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 59711795 Common - alcohol dehydrogenase II VF1188 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 59712829 Common rplM 50S ribosomal protein L13 VF2222 231 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 59711996 Common - ribosomal-protein-alanine acetyltransferase VF1389 53 COG0456 RimI, Acetyltransferases General function prediction only 59712931 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase VF2324 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 59712143 Common - SecY stabilizing membrane protein VF1536 119 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 59711243 Common xseA exodeoxyribonuclease VII large subunit VF0636 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 59712785 Common - dihydrolipoamide dehydrogenase VF2178 240 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 59712101 Common - transporter VF1494 5 None None None 59711969 Common - hypothetical protein VF1362 36 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 59711134 Common - hypothetical protein VF0527 7 None None None 59712059 Common - Na(+) driven multidrug efflux pump VF1452 127 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 59712853 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase VF2246 151 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 59711267 Common - transporter VF0660 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 59712448 Common fliQ flagellar biosynthesis protein FliQ VF1841 123 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 59711496 Common - hypothetical protein VF0889 57 COG2985 COG2985, Predicted permease General function prediction only 59710969 Common - type 4 fimbrial assembly protein PilB VF0362 223 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 59712923 Common - nitric oxide dioxygenase VF2316 144 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 59712273 Common - O-succinylbenzoic acid--CoA ligase VF1666 216 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 59711013 Common pyrB aspartate carbamoyltransferase catalytic subunit VF0406 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 59712070 Common - hypothetical protein VF1463 5 None None None 59712609 Common smpB SsrA-binding protein VF2002 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 59712077 Common - HipA protein VF1470 66 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 59710845 Common rplW 50S ribosomal protein L23 VF0238 223 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 59711522 Common - hypothetical protein VF0915 7 None None None 59711929 Common - nucleoside permease NupC VF1322 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 59711785 Common - CoA pyrophosphatase VF1178 128 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 59713057 Common - RNA polymerase sigma-32 factor VF2450 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 59713030 Common tuf elongation factor Tu VF2423 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 59713142 Common aroE shikimate 5-dehydrogenase VF2535 218 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 59711901 Common - hypothetical protein VF1294 17 COG3120 COG3120, Uncharacterized protein conserved in bacteria Function unknown 59712034 Common - sulfatase family protein VF1427 72 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 59711668 Common - anaerobic C4-dicarboxylate transporter VF1061 24 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 59711370 Common - peptidyl-tRNA hydrolase VF0763 215 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 59712643 Common - possible phage regulatory protein (CII) VF2036 7 None None None 59712079 Common - zinc finger protein VF1472 38 COG4338 COG4338, Uncharacterized protein conserved in bacteria Function unknown 59712544 Common - methyltransferase VF1937 58 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 59711292 Common - methionine transport system permease protein VF0685 193 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 59712269 Common - hypothetical DNA binding protein VF1662 8 COG4742 COG4742, Predicted transcriptional regulator Transcription 59712660 Nonpathogen - hypothetical protein VF2053 5 None None None 59712000 Common - hypothetical protein VF1393 2 None None None 59711478 Common - transcriptional regulator, TetR family VF0871 62 COG1309 AcrR, Transcriptional regulator Transcription 59712708 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase VF2101 114 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 59711963 Common - hypothetical protein VF1356 7 None None None 59712354 Common - ribosomal large subunit pseudouridine synthase C VF1747 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 59711123 Common - putative type IV secretion NTPase similar to TadA VF0516 225 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 59711228 Common hscA chaperone protein HscA VF0621 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 59711509 Common - thioredoxin reductase VF0902 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 59713087 Common - sensory box/GGDEF family protein VF2480 46 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 59712135 Common - probable transcriptional regulator SyrB VF1528 9 None None None 59711454 Common - acyl carrier protein VF0847 71 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 59710926 Common cpdB bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein VF0319 132 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 59710989 Common - Mg(2+) transporter MgtE VF0382 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 59712712 Common - ribose-5-phosphate isomerase A VF2105 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 59711276 Common - hypothetical cytosolic protein VF0669 29 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 59710630 Common - Alcohol dehydrogenase VF0023 118 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 59712466 Common - FlaI VF1859 2 None None None 59712977 Common - low-affinity zinc transport protein VF2370 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 59710960 Common - single-strand DNA-binding protein VF0353 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 59711432 Common sucC succinyl-CoA synthetase subunit beta VF0825 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 59710750 Common - N-acetylneuraminate synthase VF0143 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 59712753 Common - beta-hexosaminidase VF2146 58 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 59712701 Common - L-aspartate oxidase VF2094 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 59710934 Common - ABC transporter ATP-binding protein VF0327 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 59711443 Common - phosphate acetyltransferase VF0836 171 COG0280 Pta, Phosphotransacetylase Energy production and conversion 59711858 Common - hypothetical protein VF1251 7 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 59712974 Common - high-affinity zinc uptake system ATP-binding protein ZnuC VF2367 247 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 59711171 Common rluD 23S rRNA pseudouridine synthase D VF0564 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 59713113 Common - hypothetical protein VF2506 11 None None None 59711936 Common - soluble lytic murein transglycosylase VF1329 151 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 59712382 Common - isocitrate dehydrogenase [NADP] VF1775 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 59711786 Common - para-aminobenzoate synthase component I VF1179 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 59711819 Common - hypothetical protein VF1212 121 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 59713135 Common - ketol-acid reductoisomerase VF2528 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 59711253 Common - Thiol:disulfide interchange protein DsbA VF0646 67 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 59711409 Common - di-/tripeptide transporter VF0802 79 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 59712308 Common mnmC 5-methylaminomethyl-2-thiouridine methyltransferase VF1701 79 COG4121 COG4121, Uncharacterized conserved protein Function unknown 59712005 Common - hypothetical protein VF1398 102 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 59712182 Common - O6-methylguanine-DNA methyltransferase VF1575 103 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 59711402 Common tig trigger factor VF0795 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 59710726 Common - hypothetical protein VF0119 2 None None None 59712313 Common minE cell division topological specificity factor MinE VF1706 80 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 59713157 Common - glycogen debranching enzyme VF2550 18 COG3084 COG3084, Uncharacterized protein conserved in bacteria Function unknown 59710797 Common - hypothetical protein VF0190 2 None None None 59711164 Common - putative ABC transporter ATP-binding protein VF0557 246 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 59712719 Common - hypothetical protein VF2112 17 COG3945 COG3945, Uncharacterized conserved protein Function unknown 59711648 Common - hypothetical protein VF1041 2 None None None 59711379 Common - 2-dehydro-3-deoxyphosphooctonate aldolase VF0772 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 59710883 Common - malate dehydrogenase VF0276 190 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 59712732 Common gltD glutamate synthase subunit beta VF2125 199 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 59712914 Common - acetylornithine deacetylase VF2307 188 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 59712151 Common - phosphatidylglycerophosphatase B homolog VF1544 27 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 59710660 Common - delta-aminolevulinic acid dehydratase VF0053 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 59711428 Common sdhA succinate dehydrogenase flavoprotein subunit VF0821 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 59711058 Nonpathogen - hypothetical protein VF0451 1 None None None 59711499 Common - glutamate decarboxylase VF0892 118 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 59712116 Common - isoaspartyl dipeptidase VF1509 39 COG3964 COG3964, Predicted amidohydrolase General function prediction only 59712215 Common - molybdopterin biosynthesis MoeA protein VF1608 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 59710645 Common - Xaa-Pro aminopeptidase VF0038 184 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 59711912 Common - copper-exporting ATPase VF1305 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 59712445 Common - hypothetical protein VF1838 6 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 59712102 Common - hypothetical cytosolic protein VF1495 37 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 59712924 Common - sodium-type polar flagellar protein MotX VF2317 40 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 59712405 Common - chloride channel protein VF1798 157 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 59712241 Common nhaB sodium/proton antiporter VF1634 28 COG3067 NhaB, Na+/H+ antiporter Inorganic ion transport and metabolism 59712909 Common - hypothetical protein VF2302 4 None None None 59711037 Common - hypothetical protein VF0430 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 59712852 Common uppP undecaprenyl pyrophosphate phosphatase VF2245 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 59711383 Common - nitrite reductase [NAD(P)H] large subunit VF0776 190 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 59711032 Common - putative deoxyribonucleotide triphosphate pyrophosphatase VF0425 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 59712248 Common - DNA topoisomerase III VF1641 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 59711365 Common - PhoH-like protein VF0758 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 59712402 Common - Outer membrane protein C VF1795 22 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 59712109 Common - acylphosphatase VF1502 133 COG1254 AcyP, Acylphosphatases Energy production and conversion 59710799 Common - UDP-2-acetamido-2,6-dideoxy-beta-L-talose 4-dehydrogenase VF0192 49 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 59710727 Common - transcription accessory protein VF0120 217 COG2183 Tex, Transcriptional accessory protein Transcription 59711282 Common - urease gamma subunit VF0675 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 59712171 Common - hypothetical protein VF1564 70 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 59710961 Nonpathogen - hypothetical protein VF0354 8 None None None 59711584 Common - acetyltransferase VF0977 104 COG2153 ElaA, Predicted acyltransferase General function prediction only 59710824 Common - hypothetical protein VF0217 2 COG5589 COG5589, Uncharacterized conserved protein Function unknown 59711025 Common - diacylglycerol kinase VF0418 26 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 59712866 Common - transcriptional regulator VF2259 89 COG1802 GntR, Transcriptional regulators Transcription 59710678 Common - hypothetical protein VF0071 4 None None None 59710904 Common - acriflavin resistance periplasmic protein VF0297 92 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 59711231 Common - aminopeptidase B VF0624 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 59712827 Common - ubiquinol-cytochrome c reductase iron-sulfur subunit VF2220 83 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 59711680 Common - hypothetical protein VF1073 7 None None None 59712205 Common - exochitinase VF1598 43 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 59710668 Common - phenol hydroxylase P5 protein VF0061 96 COG0633 Fdx, Ferredoxin Energy production and conversion 59712721 Common - endonuclease IV VF2114 99 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 59711310 Common ribH riboflavin synthase subunit beta VF0703 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 59710754 Common - acylneuraminate cytidylyltransferase VF0147 69 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 59713066 Common - hypothetical protein VF2459 2 None None None 59710921 Common - FKBP-type peptidyl-prolyl cis-trans isomerase FklB VF0314 133 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 59711926 Common - spermidine/putrescine-binding protein VF1319 140 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 59711592 Common - sensory box/GGDEF family protein VF0985 181 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 59711043 Common - hypothetical protein VF0436 195 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 59712741 Common - HesB protein family VF2134 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 59711703 Common - nucleoside permease NupC VF1096 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 59711342 Common alr alanine racemase VF0735 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 59711953 Common - hypothetical protein VF1346 1 None None None 59713105 Common - DNA-directed RNA polymerase specialized sigma subunit VF2498 15 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 59713074 Common - general secretion pathway protein K VF2467 33 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 59712254 Common - hypothetical protein VF1647 3 None None None 59711728 Common - BCCT family transporter VF1121 95 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 59712761 Common - hypothetical protein VF2154 22 COG3112 COG3112, Uncharacterized protein conserved in bacteria Function unknown 59712489 Common - FlgN VF1882 7 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 59711873 Common - Na(+) driven multidrug efflux pump VF1266 157 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 59713034 Common - hypothetical protein VF2427 4 None None None 59713116 Common - 2-dehydro-3-deoxyphosphogluconate aldolase VF2509 15 None None None 59712462 Common - FlrB; two-component sensor kinase VF1855 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59713039 Common - hypothetical protein VF2432 27 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 59710972 Common - hypothetical protein VF0365 7 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 59711275 Common - sodium-glucose/galactose cotransporter VF0668 164 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 59711627 Common - tRNA pseudouridine synthase A VF1020 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 59711108 Common - Sec-independent protein translocase protein TatD VF0501 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 59712015 Common - N-acetyl-D-glucosamine kinase VF1408 136 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 59711630 Common - YciI-like protein VF1023 65 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 59712571 Common - PII uridylyl-transferase VF1964 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 59712870 Common - acetolactate synthase 3 catalytic subunit VF2263 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 161986794 Common - bifunctional aconitate hydratase 2/2-methylisocitrate dehydratase VF2158 222 COG1049 AcnB, Aconitase B Energy production and conversion 59711220 Common - tRNA pseudouridine synthase C VF0613 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 59711941 Common - oxalate/formate antiporter VF1334 5 None None None 59710975 Common - MshD VF0368 9 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 59711229 Common - ferredoxin, 2Fe-2s VF0622 85 COG0633 Fdx, Ferredoxin Energy production and conversion 59712230 Common - integral membrane protein VF1623 46 COG1289 COG1289, Predicted membrane protein Function unknown 59711020 Common - leucyl aminopeptidase VF0413 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 59712653 Common - maltose/maltodextrin transport ATP-binding protein MalK VF2046 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 59711095 Common truB tRNA pseudouridine synthase B VF0488 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 59712343 Common - hypothetical protein VF1736 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 59711257 Common - tRNA-specific adenosine deaminase VF0650 218 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 59712695 Common - signal peptidase I VF2088 212 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 59710996 Common - hypothetical protein VF0389 53 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 59712693 Common era GTP-binding protein Era VF2086 218 COG1159 Era, GTPase General function prediction only 59711489 Common - hypothetical protein VF0882 6 None None None 59711051 Common - ATP-dependent RNA helicase SrmB VF0444 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 59712018 Common - probable lipoprotein NlpC precursor VF1411 135 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 59711948 Common - cellobiose phosphotransferase system CelC VF1341 49 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 59712813 Common - UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase VF2206 213 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 59712091 Common - murein hydrolase export regulator VF1484 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 59712275 Common - naphthoate synthase VF1668 96 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 59713100 Common - thiol:disulfide interchange protein TlpA VF2493 67 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 59710804 Common - UDP-D-quinovosamine 4-dehydrogenase VF0197 144 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 59711137 Common - hypothetical protein VF0530 37 COG4628 COG4628, Uncharacterized conserved protein Function unknown 59712359 Common - uridine kinase VF1752 87 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 59710749 Common - UDP-N-acetylglucosamine 2-epimerase (N-acetylmannosamine-forming) VF0142 87 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 59710731 Common - Ttk protein VF0124 49 COG1309 AcrR, Transcriptional regulator Transcription 59710792 Common - acetolactate synthase large subunit VF0185 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 59711895 Common - hypothetical protein VF1288 16 None None None 59711393 Common - glycine betaine/L-proline transport system permease protein ProW VF0786 206 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 59712046 Common - putative ATP-dependent RNA helicase RhlE VF1439 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 59711336 Common - Na(+)-translocating NADH-quinone reductase subunit E VF0729 37 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 59712050 Common - virulence gene repressor RsaL VF1443 44 COG2944 COG2944, Predicted transcriptional regulator Transcription 59712818 Common - GS60 antigen VF2211 44 COG3107 LppC, Putative lipoprotein General function prediction only 59712233 Common uvrC excinuclease ABC subunit C VF1626 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 59712416 Common - insulin-degrading enzyme VF1809 190 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 59713058 Common - cell division protein FtsX VF2451 112 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 59713062 Common - hypothetical protein VF2455 10 COG3776 COG3776, Predicted membrane protein Function unknown 59711147 Common - oxaloacetate decarboxylase beta chain VF0540 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 59710846 Common rplB 50S ribosomal protein L2 VF0239 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 59711583 Common - glutathione synthetase VF0976 2 None None None 59712424 Common - cytochrome c-type biogenesis protein CcmH VF1817 92 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 59712480 Common flgF flagellar basal body rod protein FlgF VF1873 125 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 59711567 Nonpathogen - TolA protein VF0960 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 59712261 Common - IAA acetyltransferase VF1654 54 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 59712443 Common flhF flagellar biosynthesis regulator FlhF VF1836 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 59710838 Common - 30S ribosomal protein S7 VF0231 247 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 59712538 Common gmhA phosphoheptose isomerase VF1931 125 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 59711701 Common - SAM-dependent methyltransferase VF1094 81 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 59710835 Common - hypothetical protein VF0228 42 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 59711979 Common - permease VF1372 28 COG3819 COG3819, Predicted membrane protein Function unknown 59712268 Common - Na(+)/H(+) antiporter NhaC VF1661 37 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 59712887 Common - cAMP-regulatory protein VF2280 165 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 59712123 Common - hypothetical protein VF1516 19 None None None 59711564 Common - short chain acyl-CoA thioesterase YbgC VF0957 139 COG0824 FcbC, Predicted thioesterase General function prediction only 59711765 Common - hypothetical membrane associated protein VF1158 63 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 59712982 Common - multiple antibiotic resistance protein MarC VF2375 140 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 59713125 Common - dipeptide-binding protein VF2518 205 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 59713010 Common nudC NADH pyrophosphatase VF2403 115 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 59711914 Common - integral membrane protein VF1307 62 COG2836 COG2836, Uncharacterized conserved protein Function unknown 59711898 Common - ribosome modulation factor VF1291 21 COG3130 Rmf, Ribosome modulation factor Translation, ribosomal structure and biogenesis 59711807 Common - hypothetical protein VF1200 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 59712683 Common - CTP synthetase VF2076 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 59712772 Common - DnaK suppressor protein VF2165 112 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 59712476 Common flgJ peptidoglycan hydrolase VF1869 71 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 59711165 Common - soluble lytic murein transglycosylase VF0558 158 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 59712897 Common - hypothetical protein VF2290 29 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 59710951 Common - glycosyltransferase VF0344 161 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 59710786 Common - arabinose-5-phosphate isomerase VF0179 148 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 59713003 Common - hypothetical protein VF2396 2 None None None 59711492 Common - ABC transporter permease protein VF0885 49 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 59712437 Common - chemotaxis-specific methylesterase VF1830 197 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 59711177 Common - hypothetical protein VF0570 3 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 59710890 Common - hypothetical protein VF0283 35 COG3610 COG3610, Uncharacterized conserved protein Function unknown 59710958 Common - transcriptional regulator, TetR family VF0351 5 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 59713009 Common hemE uroporphyrinogen decarboxylase VF2402 182 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 59711358 Common holA DNA polymerase III subunit delta VF0751 72 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 59712284 Common - transcriptional regulator, AraC family VF1677 126 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 59712475 Common flgK flagellar hook-associated protein FlgK VF1868 117 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 59711470 Common - hypothetical protein VF0863 2 COG3909 COG3909, Cytochrome c556 Energy production and conversion 59711296 Common - oligopeptide transport system permease protein OppC VF0689 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 59711523 Common - general negative regulator of transcription subunit 1 VF0916 27 COG3139 COG3139, Uncharacterized protein conserved in bacteria Function unknown 59711349 Common - lipoyl synthase VF0742 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 59712087 Common - hypothetical protein VF1480 15 COG2353 COG2353, Uncharacterized conserved protein Function unknown 59710914 Common - tRNA-dihydrouridine synthase A VF0307 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 59711445 Common - hypothetical protein VF0838 23 COG3092 COG3092, Uncharacterized protein conserved in bacteria Function unknown 59713053 Common - flagellar basal body-associated protein FliL-like protein VF2446 19 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 59711687 Common - hypothetical protein VF1080 18 COG3305 COG3305, Predicted membrane protein Function unknown 59711183 Common - 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase VF0576 42 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 59712675 Common - lipoprotein NlpD VF2068 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 59711758 Common - hypothetical protein VF1151 1 None None None 59711622 Common - imidazole glycerol-phosphate dehydratase/histidinol phosphatase VF1015 218 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 59712496 Common - outer membrane porin protein precursor VF1889 17 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 59712473 Common - flagellin VF1866 125 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 59712714 Common - hypothetical protein VF2107 96 COG2968 COG2968, Uncharacterized conserved protein Function unknown 59711544 Common - repressor protein LuxO VF0937 216 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 59712282 Common - pyrimidine reductase VF1675 74 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 59712141 Common - general L-amino acid transport system permease protein AapM VF1534 181 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 59713121 Common - DNA polymerase III subunit epsilon VF2514 103 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 59711459 Common - histidine ammonia-lyase VF0852 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 59712599 Common - hypothetical protein VF1992 3 None None None 59711615 Common - hypothetical membrane spanning protein VF1008 152 COG0730 COG0730, Predicted permeases General function prediction only 59711581 Common - multidrug resistance ABC transporter ATP-binding and permease protein VF0974 247 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 59711418 Common - hypothetical protein VF0811 18 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 59710708 Common - D-tyrosyl-tRNA deacylase VF0101 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 59710864 Common secY preprotein translocase subunit SecY VF0257 238 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 59712181 Common - hypothetical protein VF1574 2 None None None 59710881 Common - immunogenic protein VF0274 88 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 59711503 Common - DNA transformation protein TfoX VF0896 19 COG3070 TfoX, Regulator of competence-specific genes Transcription 59711016 Common - hypothetical protein VF0409 23 COG3076 COG3076, Uncharacterized protein conserved in bacteria Function unknown 59712816 Common mraW S-adenosyl-methyltransferase MraW VF2209 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 59711790 Common - acriflavin resistance periplasmic protein VF1183 159 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 59711078 Common - dihydrodipicolinate reductase VF0471 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 59711372 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase VF0765 193 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 59712311 Common minC septum formation inhibitor VF1704 95 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 59711097 Common - polynucleotide phosphorylase/polyadenylase VF0490 242 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 59711241 Common - hypothetical protein VF0634 7 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 59711407 Common - peptidyl-prolyl cis-trans isomerase VF0800 170 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 59711335 Common - Na(+)-translocating NADH-quinone reductase subunit D VF0728 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 59712184 Common - acyl-CoA thioesterase II VF1577 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 59712705 Common - regulatory protein VF2098 104 COG2606 EbsC, Uncharacterized conserved protein Function unknown 59712068 Common - hypothetical protein VF1461 30 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 59713006 Common - hypothetical protein VF2399 26 COG3068 COG3068, Uncharacterized protein conserved in bacteria Function unknown 59710781 Common - beta-D-GlcNAc beta-1,3-galactosyltransferase VF0174 129 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 59711813 Common - phosphoesterase, PAP2 family VF1206 24 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 59712527 Common bcp thioredoxin-dependent thiol peroxidase VF1920 209 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 59710788 Common - CDP-6-deoxy-delta-3,4-glucoseen reductase VF0181 153 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 59712003 Common - transcriptional regulator VF1396 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 59711400 Common adk adenylate kinase VF0793 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 59711788 Common - hypothetical protein VF1181 1 None None None 59712759 Common - ammonium transporter VF2152 198 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 59711090 Common secG preprotein translocase subunit SecG VF0483 120 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 59712320 Common - ATP-dependent helicase, DinG family VF1713 155 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 59711480 Nonpathogen - hypothetical protein VF0873 1 None None None 59712794 Common - pilus assembly protein PilC VF2187 150 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 59711846 Common - oligoendopeptidase F VF1239 88 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 59711298 Common - oligopeptide transport ATP-binding protein OppD VF0691 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 59711970 Common - formate hydrogenlyase subunit 6 VF1363 63 COG1146 COG1146, Ferredoxin Energy production and conversion 59712879 Common - NADP-dependent malic enzyme VF2272 201 COG0281 SfcA, Malic enzyme Energy production and conversion 59712041 Common - putative periplasmic protein VF1434 24 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 59711903 Common - sensor protein LuxQ VF1296 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59711864 Common - hypothetical protein VF1257 7 None None None 59711511 Common - leucine-responsive transcriptional regulator VF0904 154 COG1522 Lrp, Transcriptional regulators Transcription 59712293 Common - hypothetical protein VF1686 177 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 59711159 Common rplS 50S ribosomal protein L19 VF0552 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 59712734 Nonpathogen - hypothetical protein VF2127 1 None None None 59711307 Common - 5-amino-6-(5-phosphoribosylamino)uracil reductase VF0700 224 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 59712364 Common - hypothetical protein VF1757 22 COG3771 COG3771, Predicted membrane protein Function unknown 59711900 Common - ATP-dependent protease La VF1293 91 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 59710983 Common - ribonuclease G VF0376 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 59710657 Common - sec-independent translocase VF0050 43 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 59712061 Common - Na(+)-linked D-alanine glycine permease VF1454 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 59712510 Common - cytochrome c-type protein NapC VF1903 46 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 59712385 Common - methyl-accepting chemotaxis protein VF1778 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711223 Common - Rrf2 family protein VF0616 176 COG1959 COG1959, Predicted transcriptional regulator Transcription 59710636 Common - zinc protease VF0029 139 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 59711833 Common - coproporphyrinogen III oxidase VF1226 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 59712520 Common - arsenate reductase VF1913 110 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 59711907 Common - cytochrome c oxidase, monoheme subunit, membrane-bound VF1300 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 59712334 Common - tyrosyl-tRNA synthetase VF1727 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59710773 Common - dTDP-glucose 4,6-dehydratase VF0166 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 59712804 Common ftsA cell division protein FtsA VF2197 184 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 59712202 Common - oligopeptide transport system permease protein OppC VF1595 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 59712746 Common - chitooligosaccharide-binding protein VF2139 192 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 59711128 Common - ATP/GTP-binding site motif A (P-loop) surface protein involved in fimbraea and/or secretion, TadF-like protein VF0521 7 None None None 59712645 Nonpathogen - hypothetical protein VF2038 1 None None None 59712542 Common - DNA polymerase III subunit epsilon VF1935 184 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 59712647 Common - hypothetical protein VF2040 6 None None None 59712612 Common - putative phage tail protein VF2005 11 None None None 59712071 Common - superfamily I DNA and RNA helicases VF1464 195 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 59710913 Common - zinc uptake regulation protein VF0306 166 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 59710627 Common - hypothetical protein VF0020 1 None None None 59712252 Common - aspartate-semialdehyde dehydrogenase VF1645 197 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 59711965 Common - formate dehydrogenase, cytochrome B556 subunit VF1358 28 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 59710816 Common glpX fructose 1,6-bisphosphatase II VF0209 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 59711925 Common - spermidine/putrescine-binding protein VF1318 136 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 59711718 Common - transcriptional regulators, LysR family VF1111 101 COG0583 LysR, Transcriptional regulator Transcription 59712552 Common - cell cycle protein MesJ VF1945 213 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 59711507 Common - cysteine/glutathione ABC transporter membrane/ATP-binding component VF0900 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 59712167 Common - SanA protein VF1560 46 COG2949 SanA, Uncharacterized membrane protein Function unknown 59711571 Common - Tol system periplasmic component YbgF VF0964 83 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 59711984 Common - hypothetical protein VF1377 41 COG4336 COG4336, Uncharacterized conserved protein Function unknown 59711825 Common rplT 50S ribosomal protein L20 VF1218 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 59712604 Common ppnK inorganic polyphosphate/ATP-NAD kinase VF1997 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 59712884 Common - ATP-dependent protease peptidase subunit VF2277 152 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 59713168 Common - cold shock protein VF2561 181 COG1278 CspC, Cold shock proteins Transcription 59711069 Common nhaR transcriptional activator NhaR VF0462 132 COG0583 LysR, Transcriptional regulator Transcription 59712532 Common - hypothetical protein VF1925 19 COG3249 COG3249, Uncharacterized protein conserved in bacteria Function unknown 59713080 Common - general secretion pathway protein E VF2473 211 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 59710962 Common - regulatory protein CsrD VF0355 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 59712588 Common - hypothetical protein VF1981 4 None None None 59711526 Common - short chain dehydrogenase VF0919 62 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 59712892 Common - para-aminobenzoate synthase component II VF2285 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 59711951 Common - acetyltransferase VF1344 52 COG3153 COG3153, Predicted acetyltransferase General function prediction only 59712303 Common truA tRNA pseudouridine synthase A VF1696 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 59711557 Common ruvC Holliday junction resolvase VF0950 194 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 59711324 Common - 4-methyl-5(B-hydroxyethyl)-thiazole monophosphate biosynthesis enzyme VF0717 70 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 59712936 Common - oligoribonuclease VF2329 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 59711990 Common - hypothetical protein VF1383 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 59711721 Common murQ N-acetylmuramic acid-6-phosphate etherase VF1114 86 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 59710617 Common - DNA polymerase III subunit beta VF0010 214 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 59712341 Common - DNA polymerase III, delta' subunit VF1734 212 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 59712833 Common - protease DegS precursor VF2226 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 59712933 Common - N-acetylmuramoyl-L-alanine amidase VF2326 183 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 59710857 Common rpsN 30S ribosomal protein S14 VF0250 207 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 59710693 Common - NAD(FAD)-utilizing dehydrogenase VF0086 139 COG2081 COG2081, Predicted flavoproteins General function prediction only 59711340 Common - putative periplasmic protein VF0733 24 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 59712607 Common - hypothetical protein VF2000 60 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 59712917 Common rplI 50S ribosomal protein L9 VF2310 211 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 59711259 Common - phosphoribosylformylglycinamidine synthase VF0652 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 59712114 Common - hypothetical protein VF1507 13 None None None 59711673 Common - transcriptional regulators, LysR family VF1066 172 COG0583 LysR, Transcriptional regulator Transcription 59710887 Common obgE GTPase ObgE VF0280 249 COG0536 Obg, Predicted GTPase General function prediction only 59712134 Common ansB L-asparaginase II VF1527 142 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 59712910 Common - bifunctional argininosuccinate lyase/N-acetylglutamate synthase VF2303 226 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 59712776 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase VF2169 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 59711487 Common - ribosomal small subunit pseudouridine synthase A VF0880 199 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 59711354 Common - rod shape-determining protein rodA VF0747 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 59711197 Common - cysteine desulfhydrase VF0590 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 59710703 Common glnL nitrogen regulation protein NR(II) VF0096 221 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 59711010 Common - isopentenyl-diphosphate delta-isomerase VF0403 49 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 59710875 Common thiP thiamin transporter membrane protein VF0268 110 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 59713043 Common - tRNA (uracil-5-)-methyltransferase VF2436 155 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 59710841 Common rpsJ 30S ribosomal protein S10 VF0234 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 59712899 Common aroK shikimate kinase I VF2292 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 59713095 Common - protein involved in external DNA uptake VF2488 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 59711452 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase VF0845 61 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 59712664 Common - lysine decarboxylase VF2057 87 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 59711698 Common - methyl-accepting chemotaxis protein VF1091 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711190 Common - exodeoxyribonuclease V alpha chain VF0583 130 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 59711772 Common - ABC transporter ATP-binding protein VF1165 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 59712728 Common - hypothetical protein VF2121 1 None None None 59712617 Common - hypothetical protein VF2010 5 None None None 59711250 Common - serine transporter VF0643 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 59712996 Common - Nif3 family protein VF2389 91 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 161986801 Common pyrE orotate phosphoribosyltransferase VF0112 154 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 59711998 Nonpathogen - hypothetical protein VF1391 1 None None None 59711605 Common - transcriptional regulator VF0998 169 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 59712594 Common phoR phosphate regulon sensor protein VF1987 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 59712559 Common - UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase VF1952 191 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 59712993 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit VF2386 187 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 59712378 Common - sensor protein kinase VF1771 69 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 59712032 Common - MoxR protein VF1425 179 COG0714 COG0714, MoxR-like ATPases General function prediction only 59712782 Common - hypothetical protein VF2175 2 None None None 59711651 Common - RNA-directed DNA polymerase VF1044 28 None None None 59712370 Common - arginyl-tRNA-protein transferase VF1763 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 59712223 Common - hypothetical membrane associated protein VF1616 16 COG3110 COG3110, Uncharacterized protein conserved in bacteria Function unknown 59712856 Common - O-sialoglycoprotein endopeptidase VF2249 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 59710865 Common rpmJ 50S ribosomal protein L36 VF0258 137 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 59711678 Common - CDP-4-dehydro-6-deoxy-D-glucose 3-dehydratase VF1071 30 COG5361 COG5361, Uncharacterized conserved protein Function unknown 59712100 Common - hypothetical protein VF1493 1 COG5404 SulA, SOS-response cell division inhibitor, blocks FtsZ ring formation Cell division and chromosome partitioning 59712460 Common fliE flagellar hook-basal body protein FliE VF1853 69 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 59711737 Common - 23S rRNA methyltransferase VF1130 21 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 59712622 Common - probable capsid portal protein VF2015 25 COG5518 COG5518, Bacteriophage capsid portal protein General function prediction only 59711045 Common - hypothetical protein VF0438 27 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 59711746 Common - hypothetical protein VF1139 6 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 59713182 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA VF2575 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 59711111 Common - deoxyribose-phosphate aldolase VF0504 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 59711201 Common xni exonuclease IX VF0594 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 59712561 Common - outer membrane protein assembly factor YaeT VF1954 161 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 59711579 Common - RNA polymerase sigma factor SigZ VF0972 115 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 59712762 Common - carbohydrate diacid regulator VF2155 41 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 59711060 Common lysS lysyl-tRNA synthetase VF0453 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 59710758 Common - O-antigen ligase VF0151 8 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 59712743 Common - hypothetical membrane spanning protein VF2136 112 COG0628 PerM, Predicted permease General function prediction only 59712478 Common flgH flagellar basal body L-ring protein VF1871 98 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 59711140 Common - long-chain-fatty-acid--CoA ligase VF0533 218 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 59712547 Common - hypothetical protein VF1940 4 None None None 59712037 Common - sulfatase family protein VF1430 79 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 59713068 Common - predicted gluconate transport-associated protein VF2461 64 COG0316 IscA, Uncharacterized conserved protein Function unknown 59710873 Common - aromatic acid decarboxylase VF0266 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 59710994 Common - RNA polymerase factor sigma-54 VF0387 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 59712330 Common - hypothetical protein VF1723 4 None None None 59713036 Nonpathogen - hypothetical protein VF2429 1 None None None 59711866 Common - hypothetical protein VF1259 30 COG3059 COG3059, Predicted membrane protein Function unknown 59712130 Common - CBS domain containing protein VF1523 128 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 59711966 Common - formate dehydrogenase (cytochrome b) iron-sulfur subunit VF1359 165 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 59712825 Common - cytochrome b VF2218 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 59710872 Common - UDP-N-acetylmuramate:L-alanyl-gamma-D-glutamyl-meso-diaminopimelate ligase VF0265 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 59713076 Common - general secretion pathway protein I VF2469 26 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 59713107 Common - hypothetical protein VF2500 1 None None None 59712515 Common - nitrate/nitrite sensor protein NarQ VF1908 145 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 59711319 Common - dimethylallyltransferase VF0712 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 59712903 Common - pili assembly protein PilN VF2296 43 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 59712247 Common - hypothetical protein VF1640 14 None None None 59711490 Common - nucleoside-diphosphate-sugar epimerase VF0883 51 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 59712120 Common - sodium:dicarboxylate symporter family protein YdjN VF1513 161 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 59711329 Common - putative lipoprotein VF0722 10 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 59712597 Common - peptidase family U32 VF1990 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 59712118 Common - 2',3'-cyclic-nucleotide 2'-phosphodiesterase VF1511 121 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 59712723 Common - threonine synthase VF2116 195 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 59712216 Common - molybdopterin biosynthesis protein MoeB VF1609 220 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 59712697 Common - putative sigma-E factor regulatory protein VF2090 24 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 59710829 Common - hypothetical protein VF0222 24 COG3529 COG3529, Predicted nucleic-acid-binding protein containing a Zn-ribbon domain General function prediction only 59712630 Common - phage protein VF2023 6 COG4381 COG4381, Mu-like prophage protein gp46 Function unknown 59711891 Common - NAD-specific glutamate dehydrogenase VF1284 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 59712966 Common - protein tyrosine phosphatase VF2359 15 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 59712811 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase VF2204 225 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 59711214 Common - PTS system, diacetylchitobiose-specific IIA component VF0607 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 59712407 Common - HIT family hydrolase VF1800 66 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 59711027 Common - membrane-bound lytic murein transglycosylase C precursor VF0420 22 None None None 59710936 Common - protein YtfJ precursor VF0329 17 COG3054 COG3054, Predicted transcriptional regulator General function prediction only 59711958 Nonpathogen - hypothetical protein VF1351 4 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 59712366 Common rpsA 30S ribosomal protein S1 VF1759 216 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 59710850 Common rplP 50S ribosomal protein L16 VF0243 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 59711389 Common - transcriptional regulator, MerR family VF0782 138 COG0789 SoxR, Predicted transcriptional regulators Transcription 59711823 Common - bacterial protein translation initiation factor 3 (IF-3) VF1216 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 59711093 Common infB translation initiation factor IF-2 VF0486 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 59713041 Common - hypothetical protein VF2434 30 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 59710662 Common - ATP-dependent RNA helicase VF0055 230 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 59711497 Common grxA glutaredoxin 1 VF0890 41 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 59711367 Common - 2-octaprenyl-3-methyl-6-methoxy-1,4-benzoquinol hydroxylase VF0760 127 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 59711381 Common - nitrite transporter VF0774 88 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 59712872 Common leuO leucine transcriptional activator VF2265 158 COG0583 LysR, Transcriptional regulator Transcription 59710943 Common - Na(+)/H(+) antiporter NhaP VF0336 146 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 59711284 Common - putative dipeptide ABC transporter VF0677 237 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 59710609 Common trmE tRNA modification GTPase TrmE VF0002 224 COG0486 ThdF, Predicted GTPase General function prediction only 59711009 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase VF0402 150 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 59711313 Common - phosphatidylglycerophosphatase A VF0706 105 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 59712926 Common - hypothetical protein VF2319 18 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 59710643 Common thiH thiamine biosynthesis protein ThiH VF0036 57 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 59710768 Nonpathogen - hypothetical protein VF0161 1 None None None 59713110 Common - transcriptional regulator VF2503 11 None None None 59711586 Nonpathogen - hypothetical protein VF0979 1 None None None 59711733 Nonpathogen - hypothetical protein VF1126 2 None None None 59712107 Common - ATP-dependent RNA helicase HrpA VF1500 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 59711039 Common - pili retraction protein PilU VF0432 220 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 59711004 Common - toluene tolerance protein TTG2D VF0397 46 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 59712868 Common - sensory box/GGDEF family protein VF2261 180 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 59710806 Common - hypothetical protein VF0199 200 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 59711763 Common - chlorohydrolase/deaminase family protein VF1156 177 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 59710880 Common - transporter VF0273 86 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 59712830 Common - ATPase VF2223 103 COG1485 COG1485, Predicted ATPase General function prediction only 59710822 Common - hypothetical protein VF0215 30 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 59712687 Common - GTP pyrophosphokinase VF2080 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 59711658 Common - DNA topoisomerase I VF1051 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 59712160 Common - cytochrome c-type protein NrfB VF1553 16 None None None 59711517 Common - dsDNA-mimic protein VF0910 18 COG3099 COG3099, Uncharacterized protein conserved in bacteria Function unknown 59711476 Common - hypothetical protein VF0869 18 COG3811 COG3811, Uncharacterized protein conserved in bacteria Function unknown 59712439 Common - chemotaxis protein CheZ VF1832 45 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59713146 Common - DNA topoisomerase I VF2539 140 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 59712286 Nonpathogen - hypothetical protein VF1679 1 None None None 59712098 Common - hypothetical protein VF1491 7 None None None 59712928 Common - protease activity modulator HflK VF2321 213 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 59712089 Common sbcB exonuclease I VF1482 51 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 59712194 Common - lysine-arginine-ornithine-binding protein VF1587 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 59712431 Common - heme exporter protein A VF1824 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 59712565 Common - undecaprenyl pyrophosphate synthetase VF1958 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 59710682 Common - GTPase EngB VF0075 175 COG0218 COG0218, Predicted GTPase General function prediction only 59711080 Common carB carbamoyl phosphate synthase large subunit VF0473 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 59712685 Common - putative beta-lactamase regulatory protein VF2078 155 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 59712105 Common hemH phosphoribosylaminoimidazole-succinocarboxamide synthase VF1498 118 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 59711752 Common - hypothetical protein VF1145 2 None None None 59711181 Common - transcriptional regulators, LysR family VF0574 89 COG0583 LysR, Transcriptional regulator Transcription 59710985 Common - beta-ureidopropionase VF0378 202 COG0388 COG0388, Predicted amidohydrolase General function prediction only 59711331 Common - BolA protein VF0724 99 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 59711709 Nonpathogen - hypothetical protein VF1102 1 None None None 59712326 Common - bifunctional maltose and glucose-specific PTS system components IICB VF1719 50 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 59712235 Common - DNA polymerase II VF1628 65 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 59711163 Common - hypothetical protein VF0556 16 None None None 59711689 Common - glutathione S-transferase VF1082 104 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 59712082 Common - transcriptional regulators, LysR family VF1475 45 COG0583 LysR, Transcriptional regulator Transcription 59712048 Nonpathogen - hypothetical protein VF1441 1 None None None 59712666 Common - Na(+)-linked D-alanine glycine permease VF2059 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 59711856 Common - phosphoenolpyruvate phosphomutase VF1249 97 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 59711356 Common - hypothetical protein VF0749 167 COG1576 COG1576, Uncharacterized conserved protein Function unknown 59711939 Common - Na(+) driven multidrug efflux pump VF1332 144 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 59711646 Common - short chain dehydrogenase VF1039 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 59712577 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase VF1970 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 59711056 Common - thiol:disulfide interchange protein DsbC VF0449 67 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 59710953 Common - hypothetical protein VF0346 76 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 59713127 Common - cytochrome c5 VF2520 48 COG3245 CycB, Cytochrome c5 Energy production and conversion 59712498 Common - cell division protein ZipA VF1891 42 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 59712673 Common - hypothetical protein VF2066 9 COG5413 COG5413, Uncharacterized integral membrane protein Function unknown 59711175 Common - hypothetical protein VF0568 2 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 59711469 Common - 50S ribosomal protein L25 VF0862 129 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 59711447 Common - hypothetical protein VF0840 19 COG3102 COG3102, Uncharacterized protein conserved in bacteria Function unknown 59710784 Common - 3-deoxy-manno-octulosonate-8-phosphatase VF0177 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 59712602 Nonpathogen - hypothetical protein VF1995 1 None None None 59712639 Nonpathogen - hypothetical protein VF2032 1 None None None 59713051 Common ubiA 4-hydroxybenzoate octaprenyltransferase VF2444 189 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 59711484 Common - transcriptional regulators, LysR family VF0877 186 COG0583 LysR, Transcriptional regulator Transcription 59711101 Common - sensory transduction protein kinase VF0494 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 59711883 Common - paraquat-inducible protein A VF1276 54 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 59712558 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase VF1951 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 59711946 Common - hypothetical protein VF1339 3 None None None 59711170 Common - Lipoprotein, ComL family VF0563 122 COG4105 ComL, DNA uptake lipoprotein General function prediction only 59711629 Common - hypothetical protein VF1022 2 None None None 59710794 Nonpathogen - hypothetical protein VF0187 7 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 59710725 Common - BioH protein VF0118 164 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 59710733 Common radC DNA repair protein RadC VF0126 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 59713133 Common - 2-dehydropantoate 2-reductase VF2526 29 None None None 59711529 Common - glutaredoxin VF0922 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 59712876 Common - glycosidase VF2269 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 59710712 Common rpoZ DNA-directed RNA polymerase subunit omega VF0105 107 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 59712052 Common - D-ribose transporter ATP binding protein VF1445 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 59711875 Common - hypothetical protein VF1268 171 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 59712880 Common rpmE 50S ribosomal protein L31 VF2273 204 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 59710688 Common - DNA-binding transcriptional regulator AsnC VF0081 152 COG1522 Lrp, Transcriptional regulators Transcription 59712173 Common - hypothetical protein VF1566 13 COG4720 COG4720, Predicted membrane protein Function unknown 59712536 Common - phosphoribosylglycinamide formyltransferase VF1929 223 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 59712065 Common - threonine synthase VF1458 179 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 59711411 Common asnB asparagine synthetase B VF0804 162 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 59712263 Common - hypothetical protein VF1656 200 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 59711555 Common - methyltransferase VF0948 56 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 59710775 Common - dTDP-4-dehydrorhamnose 3,5-epimerase VF0168 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 59711338 Common - Na(+)-translocating NADH-quinone reductase subunit F VF0731 148 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 59713064 Common - hypothetical protein VF2457 11 None None None 59712491 Common - hypothetical protein VF1884 13 COG5616 COG5616, Predicted integral membrane protein Function unknown 59711561 Common - cytochrome d ubiquinol oxidase subunit II VF0954 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 59710739 Common coaD phosphopantetheine adenylyltransferase VF0132 209 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 59711530 Common - hypothetical protein VF0923 13 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 59711462 Common - transporter VF0855 42 COG4258 COG4258, Predicted exporter General function prediction only 59712482 Common flgD flagellar basal body rod modification protein VF1875 110 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 59712581 Common - hydrogen peroxide-inducible genes activator VF1974 185 COG0583 LysR, Transcriptional regulator Transcription 59711087 Common - dihydropteroate synthase VF0480 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 59710892 Common apaH diadenosine tetraphosphatase VF0285 71 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 59711149 Common - peptidase family M16 VF0542 198 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 59710752 Common - mannose-1-phosphate guanyltransferase VF0145 225 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 59712418 Common fadI 3-ketoacyl-CoA thiolase VF1811 172 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 59710809 Common - phosphoglyceromutase VF0202 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 59710691 Common - ferritin VF0084 80 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 59711208 Common - hypothetical protein VF0601 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 59711982 Common - kinase autophosphorylation inhibitor KipI VF1375 98 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 59712306 Common - erythronate-4-phosphate dehydrogenase VF1699 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 59710701 Common - sensory box/GGDEF family protein VF0094 174 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 59712556 Common lpxB lipid-A-disaccharide synthase VF1949 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 59712736 Common - adenosylcobinamide-phosphate synthase VF2129 25 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 59710814 Common - 5-carboxymethyl-2-hydroxymuconate delta-isomerase VF0207 30 COG3232 HpaF, 5-carboxymethyl-2-hydroxymuconate isomerase Amino acid transport and metabolism 59711398 Common - toxin transcriptional activator ToxR VF0791 49 COG3710 CadC, DNA-binding winged-HTH domains Transcription 59712865 Common - pyruvate kinase VF2258 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 59712943 Common - fumarate reductase subunit C VF2336 23 COG3029 FrdC, Fumarate reductase subunit C Energy production and conversion 59711909 Common - cytochrome c oxidase, diheme subunit, membrane-bound VF1302 79 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 59710641 Common - molybdopterin biosynthesis MoeB protein VF0034 222 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 59711905 Nonpathogen - hypothetical protein VF1298 2 None None None 59712250 Common - signal peptide peptidase SppA VF1643 188 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 59711844 Common ihfA integration host factor subunit alpha VF1237 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 59711017 Common - hypothetical protein VF0410 3 None None None 59712063 Common - homoserine/homoserine lactone efflux protein VF1456 120 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 59713025 Common - LSU ribosomal protein L1P VF2418 170 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 59710634 Common - Trk system potassium uptake protein TrkH VF0027 120 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 59711157 Common rimM 16S rRNA-processing protein VF0550 177 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 59710930 Common - adenylylsulfate kinase VF0323 145 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 59712501 Common - phosphocarrier protein HPr VF1894 135 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 59712649 Common - methyl-accepting chemotaxis protein VF2042 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711235 Common - integral membrane protein VF0628 71 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 59712570 Common - methionine aminopeptidase VF1963 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 59711270 Common - N-acetylneuraminate lyase VF0663 219 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 59711374 Common hemA glutamyl-tRNA reductase VF0767 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 59712073 Common - small heat shock protein VF1466 65 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 59711748 Common - beta-glucosidase VF1141 21 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 59712030 Common - hypothetical protein VF1423 7 None None None 59711085 Common rrmJ 23S rRNA methyltransferase J VF0478 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 59712802 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase VF2195 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 59713180 Common - chromosome partitioning protein ParA VF2573 225 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 59712139 Common - general L-amino acid-binding protein VF1532 113 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 59712620 Common - probable capsid scaffolding protein VF2013 22 None None None 59711248 Common - hypothetical protein VF0641 35 COG3681 COG3681, Uncharacterized conserved protein Function unknown 59713078 Common - general secretion pathway protein G VF2471 105 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 59712132 Common - anaerobic glycerol-3-phosphate dehydrogenase subunit C VF1525 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 59711553 Common - ATP-dependent Zn protease VF0946 37 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 59713082 Common - general secretion pathway protein C VF2475 32 COG3031 PulC, Type II secretory pathway, component PulC Intracellular trafficking and secretion 59712336 Common - hypothetical protein VF1729 5 None None None 59712748 Common - chitooligosaccharide transport system permease protein VF2141 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 59713160 Common - thiol:disulfide interchange protein DsbA VF2553 67 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 59712970 Common - glyceraldehyde 3-phosphate dehydrogenase VF2363 12 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 59712001 Common - glycine betaine transporter VF1394 95 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 59711760 Common - hypothetical protein VF1153 31 COG4807 COG4807, Uncharacterized protein conserved in bacteria Function unknown 59711501 Common - putative surface protein VF0894 49 COG2431 COG2431, Predicted membrane protein Function unknown 59711815 Common - hypothetical protein VF1208 16 COG3097 COG3097, Uncharacterized protein conserved in bacteria Function unknown 59711012 Common - aspartate carbamoyltransferase regulatory subunit VF0405 64 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 59711923 Common potB spermidine/putrescine ABC transporter membrane protein VF1316 216 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 59712039 Common - hypothetical protein VF1432 26 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 59713123 Common - dipeptide transport system permease protein DppC VF2516 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 59713171 Common - F0F1 ATP synthase subunit beta VF2564 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 59713178 Common - F0F1 ATP synthase subunit I VF2571 20 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 59711632 Common - intracellular septation protein A VF1025 89 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 59713022 Common rplL 50S ribosomal protein L7/L12 VF2415 210 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 59712841 Common - bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase VF2234 150 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 59713166 Common - dihydroxy-acid dehydratase VF2559 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 59711405 Common - ATP-dependent protease La VF0798 215 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 59711636 Common - bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase VF1029 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 59710939 Common - outer membrane protein VF0332 130 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 59712155 Common - cytochrome c-type biogenesis protein CcmH VF1548 89 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 59711665 Common - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase VF1058 175 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 59711930 Common - lipoprotein VF1323 46 COG1359 COG1359, Uncharacterized conserved protein Function unknown 59713131 Common - acriflavin resistance plasma membrane protein VF2524 179 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 59712321 Common purU formyltetrahydrofolate deformylase VF1714 220 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 59710672 Common - uroporphyrinogen-III synthase VF0065 66 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 59712441 Common fliA flagellar biosynthesis sigma factor VF1834 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 59712190 Common - exonuclease III VF1583 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 59711450 Common - hypothetical protein VF0843 4 None None None 59711440 Common - ferrous iron transport protein A VF0833 40 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 59711433 Common - succinyl-CoA synthetase subunit alpha VF0826 217 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 59711482 Common secD preprotein translocase subunit SecD VF0875 204 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 59711644 Common - autoinducer synthase AinS VF1037 2 None None None 59711782 Common - hypothetical protein VF1175 1 None None None 59712186 Common - cysteine synthase VF1579 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 59712757 Common - iron(III)-transport system permease protein SfuB VF2150 188 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 59711118 Common - hypothetical protein VF0511 5 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 59711464 Common - 3-oxoacyl-(acyl carrier protein) synthase I VF0857 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 59711457 Common - AMP-(fatty)acid ligase VF0850 21 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 59710879 Common - universal stress protein family VF0272 132 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 59712529 Common - zinc metalloprotease VF1922 124 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 59711676 Nonpathogen - hypothetical protein VF1069 1 None None None 59712953 Common - serine acetyltransferase VF2346 172 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 59710964 Common - hypothetical protein VF0357 15 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 59712768 Common - methyl-accepting chemotaxis protein VF2161 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59710777 Common - flippase VF0170 63 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 59711352 Common - D-alanyl-D-alanine serine-type carboxypeptidase VF0745 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 59711113 Common - phosphopentomutase VF0506 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 59710867 Common - 30S ribosomal protein S11 VF0260 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 59712295 Common - adenine phosphoribosyltransferase VF1688 190 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 59712619 Common - major capsid protein precursor VF2012 22 None None None 59712632 Common - putative phage baseplate assembly protein VF2025 14 COG4384 COG4384, Mu-like prophage protein gp45 Function unknown 59711739 Common - alpha-amylase VF1132 41 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 59711611 Common - hypothetical cytosolic protein VF1004 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 59711073 Common - bifunctional riboflavin kinase/FMN adenylyltransferase VF0466 211 COG0196 RibF, FAD synthase Coenzyme metabolism 59710893 Common ksgA dimethyladenosine transferase VF0286 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 59712372 Common clpA ATP-dependent Clp protease ATP-binding subunit VF1765 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 59712392 Common - hypothetical protein VF1785 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 59711671 Common - glutamate decarboxylase VF1064 69 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 59712998 Common fis DNA-binding protein Fis VF2391 96 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 59711770 Common - export ABC transporter permease protein VF1163 177 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 59712624 Common - L-alanyl-D-glutamate peptidase VF2017 5 None None None 59710949 Common - UTP--glucose-1-phosphate uridylyltransferase VF0342 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 59711519 Common - aldose 1-epimerase-like protein VF0912 65 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 59711809 Common - ribonucleotide-diphosphate reductase subunit alpha VF1202 203 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 59711603 Common - probable lipoprotein [imported] VF0996 31 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 59711779 Common - tyrosine-specific transport protein VF1172 43 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 59710925 Common - transcription regulator, Crp family VF0318 24 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 59711757 Common - transcriptional regulator VF1150 52 COG1584 COG1584, Predicted membrane protein Function unknown 59711505 Common - hypothetical protein VF0898 3 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 59711273 Common - N-acetylmannosamine-6-phosphate 2-epimerase VF0666 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 59710621 Common avtA valine--pyruvate transaminase VF0014 180 COG3977 COG3977, Alanine-alpha-ketoisovalerate (or valine-pyruvate) aminotransferase Amino acid transport and metabolism 59711196 Common - SufE protein VF0589 94 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 59712228 Common mgsA methylglyoxal synthase VF1621 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 59710897 Common djlA Dna-J like membrane chaperone protein VF0290 85 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 59712027 Common - hypothetical protein VF1420 22 None None None 59713090 Common xerC site-specific tyrosine recombinase XerC VF2483 228 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 59712169 Common - hypothetical protein VF1562 7 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 59711559 Common ruvB Holliday junction DNA helicase B VF0952 240 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 59712020 Common - phosphatidylserine decarboxylase VF1413 70 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 59711546 Common - hypothetical cytosolic protein VF0939 92 COG0391 COG0391, Uncharacterized conserved protein Function unknown 59711988 Common - hypothetical protein VF1381 1 None None None 59711577 Common - C factor cell-cell signaling protein VF0970 66 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 59712195 Common - histidine transport ATP-binding protein HisP VF1588 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 59712399 Common - regulatory protein VF1792 113 COG2606 EbsC, Uncharacterized conserved protein Function unknown 59711799 Common - hypothetical protein VF1192 19 COG3489 COG3489, Predicted periplasmic lipoprotein General function prediction only 59712716 Common - hypothetical protein VF2109 87 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 59711047 Common - transketolase VF0440 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 59711601 Common - hypothetical membrane associated protein VF0994 39 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 59711391 Common - short chain dehydrogenase VF0784 232 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 59712221 Common - hypothetical protein VF1614 2 None None None 59711802 Common - hypothetical protein VF1195 2 None None None 59712651 Common - maltose transport system permease protein MalF VF2044 153 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 59712459 Common fliF flagellar MS-ring protein VF1852 124 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 59712831 Common - cytochrome d ubiquinol oxidase subunit III VF2224 27 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 59711070 Common - transcriptional activator HlyU VF0463 168 COG0640 ArsR, Predicted transcriptional regulators Transcription 59711992 Common - hypothetical protein VF1385 4 COG0456 RimI, Acetyltransferases General function prediction only 59711831 Common - TolQ protein VF1224 3 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 59712506 Nonpathogen - hypothetical protein VF1899 2 None None None 59712150 Common - long-chain fatty acid transport protein precursor VF1543 70 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 59711305 Common - methyl-accepting chemotaxis protein VF0698 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711126 Common - secretory protein containing TPR-repeats, similar to TadD VF0519 7 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 59711264 Common - succinylglutamate desuccinylase/aspartoacylase family protein VF0657 56 COG3608 COG3608, Predicted deacylase General function prediction only 59711732 Nonpathogen - hypothetical protein VF1125 2 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 59712347 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase VF1740 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 59712568 Common tsf elongation factor Ts VF1961 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 59711326 Common - hypothetical protein VF0719 8 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 59712176 Common - hypothetical protein VF1569 3 None None None 59712788 Common - pyruvate dehydrogenase E1 component VF2181 164 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 59710615 Common - cystine-binding protein VF0008 170 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 59712988 Common - cyclic nucleotide binding protein/2 CBS domains VF2381 64 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 59710628 Common - transcriptional regulators, LysR family VF0021 93 COG0583 LysR, Transcriptional regulator Transcription 59711139 Common codB cytosine permease VF0532 76 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 59711102 Common - sterol binding protein VF0495 33 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 59712781 Common - carbonic anhydrase VF2174 148 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 59710885 Common rplU 50S ribosomal protein L21 VF0278 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 59712277 Common - acyl-CoA thioester hydrolase YfbB VF1670 93 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 59710655 Common ubiB putative ubiquinone biosynthesis protein UbiB VF0048 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 59711690 Common - putative glutathione S-transferase YghU VF1083 97 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 59712129 Common zntA zinc/cadmium/mercury/lead-transporting ATPase VF1522 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 59711594 Common - methyl-accepting chemotaxis protein VF0987 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59712658 Common - transcriptional regulators, LysR family VF2051 173 COG0583 LysR, Transcriptional regulator Transcription 59711130 Common - outer membrane protein VF0523 153 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 59711617 Common - hypothetical protein VF1010 2 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 59712890 Common - arginine N-succinyltransferase, beta chain VF2283 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 59710852 Common rpsQ 30S ribosomal protein S17 VF0245 237 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 59712452 Common fliM flagellar motor switch protein FliM VF1845 113 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 59713139 Nonpathogen - hypothetical protein VF2532 1 None None None 59711536 Common - endonuclease III VF0929 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 59712784 Common - LitR, transcriptional regulator VF2177 34 COG1309 AcrR, Transcriptional regulator Transcription 59712901 Common - pilus expression protein VF2294 37 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 59711023 Common - proline-rich antigen VF0416 27 COG1714 COG1714, Predicted membrane protein/domain Function unknown 59711351 Common - hypothetical protein VF0744 53 COG2921 COG2921, Uncharacterized conserved protein Function unknown 59711210 Common - PTS system, cellobiose-specific IIC component VF0603 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 59712368 Common - 3-phosphoshikimate 1-carboxyvinyltransferase VF1761 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 59711821 Common - threonyl-tRNA synthetase VF1214 224 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59713028 Common - transcription antitermination protein NusG VF2421 210 COG0250 NusG, Transcription antiterminator Transcription 59711968 Nonpathogen - hypothetical protein VF1361 1 None None None 59712663 Common - pyridoxine kinase VF2056 77 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 59713093 Common cyaY frataxin-like protein VF2486 43 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 59710853 Common - LSU ribosomal protein L14P VF0246 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 59711302 Common glyA serine hydroxymethyltransferase VF0695 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 59713102 Nonpathogen - hypothetical protein VF2495 1 None None None 59712991 Common - acetyl-coenzyme A synthetase VF2384 213 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 59711512 Common - cell division protein FtsK VF0905 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 59711597 Common - serine/threonine protein kinase VF0990 143 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 59710966 Common - general secretion pathway protein D VF0359 143 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 59710698 Common - sensory box/GGDEF family protein VF0091 177 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 59712656 Common - cyclomaltodextrinase VF2049 166 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 59713014 Common - CsgE-like protein VF2407 4 None None None 59711320 Common - exodeoxyribonuclease VII small subunit VF0713 135 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 59712888 Common - hypothetical protein VF2281 20 None None None 59712787 Common - pyruvate dehydrogenase E1 component VF2180 95 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 59712162 Common - cytochrome c-type biogenesis protein CcmI VF1555 14 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 59711735 Common - hypothetical protein VF1128 18 COG1106 COG1106, Predicted ATPases General function prediction only 59713002 Common - phosphoribosylamine--glycine ligase VF2395 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 59711065 Common - hypothetical protein VF0458 113 COG0730 COG0730, Predicted permeases General function prediction only 59712845 Common - putative adenylate cyclase family VF2238 58 COG3025 COG3025, Uncharacterized conserved protein Function unknown 59711075 Common lspA lipoprotein signal peptidase VF0468 116 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 59712837 Common - cyclic 3',5'-adenosine monophosphate phosphodiesterase VF2230 72 COG1409 Icc, Predicted phosphohydrolases General function prediction only 59711843 Common pheT phenylalanyl-tRNA synthetase subunit beta VF1236 246 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 59712332 Common - secretory tripeptidyl aminopeptidase VF1725 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 59710895 Common - peptidyl-prolyl cis-trans isomerase VF0288 155 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 59711612 Common - Flagellar L-ring protein FlgH VF1005 23 None None None 59712398 Common - serine protease VF1791 129 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 59711254 Common - proton/sodium-glutamate symport protein VF0647 145 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 59712146 Common - transporter VF1539 190 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 59712944 Common - fumarate reductase subunit D VF2337 21 COG3080 FrdD, Fumarate reductase subunit D Energy production and conversion 59711962 Nonpathogen - hypothetical protein VF1355 3 None None None 59712465 Common fliS flagellar protein FliS VF1858 87 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 59711053 Common - branched chain amino acid transport system II carrier protein VF0446 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 59711793 Common - cystathionine beta-lyase VF1186 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 59712192 Common - histidine transport system permease protein HisM VF1585 174 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 59713138 Nonpathogen - hypothetical protein VF2531 1 None None None 59712502 Common - phosphoenolpyruvate-protein phosphotransferase VF1895 143 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 59712456 Common fliI flagellum-specific ATP synthase VF1849 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 59711754 Common - carbon starvation protein A VF1147 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 59711742 Common - hypothetical protein VF1135 28 COG3014 COG3014, Uncharacterized protein conserved in bacteria Function unknown 59710899 Common leuD isopropylmalate isomerase small subunit VF0292 210 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 59711725 Common - cellulose synthase operon C protein VF1118 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 59712024 Common - arylsulfatase regulator (Fe-S oxidoreductase) VF1417 95 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 59712218 Common - phosphate transport system permease protein PstC VF1611 232 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 59712968 Common - transcriptional regulator, ArsR family VF2361 141 COG0640 ArsR, Predicted transcriptional regulators Transcription 59711191 Common - quaternary ammonium compound-resistance protein VF0584 108 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 59711205 Common queF 7-cyano-7-deazaguanine reductase VF0598 83 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 59710859 Common rplF 50S ribosomal protein L6 VF0252 234 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 59712373 Common clpS ATP-dependent Clp protease adaptor protein ClpS VF1766 121 COG2127 COG2127, Uncharacterized conserved protein Function unknown 59711750 Common - NADH dehydrogenase VF1143 189 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 59712564 Common - phosphatidate cytidylyltransferase VF1957 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 59712471 Common - flagellin VF1864 123 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 59711973 Common - FdhD protein (FdsC) VF1366 133 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 59710613 Common - cystine transport ATP-binding protein VF0006 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 59710998 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase VF0391 103 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 59712964 Common nagB glucosamine-6-phosphate deaminase VF2357 83 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 59711394 Common - glycine betaine/L-proline transport ATP-binding protein ProV VF0787 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 59712952 Common - 23S rRNA methyltransferase VF2345 159 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 59710762 Common - transcriptional regulator, TetR family VF0155 48 COG1309 AcrR, Transcriptional regulator Transcription 59711194 Common mltA murein transglycosylase A VF0587 92 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 59711796 Common ribA GTP cyclohydrolase II VF1189 179 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 59711776 Common - acyl-CoA hydrolase VF1169 130 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 59710778 Nonpathogen - hypothetical protein VF0171 2 None None None 59711818 Common - hypothetical protein VF1211 34 COG1359 COG1359, Uncharacterized conserved protein Function unknown 59712383 Common - ribosomal large subunit pseudouridine synthase E VF1776 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 59710878 Common - ribosomal large subunit pseudouridine synthase A VF0271 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 59712008 Common - C4-dicarboxylate transport transcriptional regulatory protein DctD VF1401 196 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 59712861 Common - RNA polymerase sigma factor RpoD VF2254 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 59712999 Nonpathogen - hypothetical protein VF2392 1 None None None 59712808 Common murG N-acetylglucosaminyl transferase VF2201 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 59712718 Common - hypothetical protein VF2111 1 None None None 59710723 Common - xanthine permease VF0116 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 59712911 Common - argininosuccinate synthase VF2304 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 59711541 Common - electron transport complex protein RnfB VF0934 121 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 59712337 Common - sodium/proline symporter VF1730 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 59712185 Common - transcriptional regulator, AsnC family VF1578 166 COG1522 Lrp, Transcriptional regulators Transcription 59713172 Common - F0F1 ATP synthase subunit gamma VF2565 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 59712618 Nonpathogen - hypothetical protein VF2011 1 None None None 59711675 Common - pirin VF1068 148 COG1741 COG1741, Pirin-related protein General function prediction only 59712522 Common - D-alanyl-D-alanine carboxypeptidase VF1915 33 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 59713130 Common - periplasmic component of efflux system VF2523 175 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 59710629 Common - hypothetical protein VF0022 12 COG4682 COG4682, Predicted membrane protein Function unknown 59712188 Common - acriflavin resistance plasma membrane protein VF1581 182 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 59711839 Common - hypothetical protein VF1232 1 None None None 59712858 Common - GatB/YqeY domain protein VF2251 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 59712316 Common - hydrolase VF1709 93 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 59712702 Nonpathogen - hypothetical protein VF2095 1 None None None 59710633 Common - hypothetical protein VF0026 132 COG1739 COG1739, Uncharacterized conserved protein Function unknown 59711371 Common - ribose-phosphate pyrophosphokinase VF0764 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 59711935 Common - ferrichrome-binding protein VF1328 41 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 59712844 Common - potassium channel protein VF2237 88 None None None 59712754 Common - N,N'-diacetylchitobiose phosphorylase VF2147 45 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 59711670 Common - transcriptional regulator VF1063 180 COG0583 LysR, Transcriptional regulator Transcription 59711710 Common - hypothetical protein VF1103 49 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 59710965 Common - hypothetical protein VF0358 2 None None None 59712601 Common dnaK molecular chaperone DnaK VF1994 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 59711707 Common - D-cysteine desulfhydrase homolog VF1100 10 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 59711784 Common - serine transporter VF1177 38 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 59712978 Common - hypothetical protein VF2371 8 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 59711642 Common - Sua5/YciO/YrdC/YwlC family protein VF1035 201 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 59711403 Common clpP ATP-dependent Clp protease proteolytic subunit VF0796 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 59712035 Common - sulfatase family protein VF1428 72 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 59711244 Common - inositol-5-monophosphate dehydrogenase VF0637 237 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 59712549 Common - nitrogen regulatory protein GlnK VF1942 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 59713023 Common - LSU ribosomal protein L10P VF2416 180 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 59713154 Common - Trk system potassium uptake protein TrkH VF2547 127 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 59710986 Common - TldD protein VF0379 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 59712355 Common - ribonuclease E VF1748 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 59710929 Common - transporter, divalent anion:sodium symporter family VF0322 124 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 59711213 Common - glucokinase VF0606 130 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 59713086 Common - hypothetical protein VF2479 12 None None None 59711980 Common - transporter VF1373 27 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 59712328 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase VF1721 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 59711886 Common - putative solute/DNA competence effector VF1279 33 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 59711618 Common - hypothetical protein VF1011 4 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 59712575 Common yajC preprotein translocase subunit YajC VF1968 175 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 59712297 Common - transcriptional regulators, LysR family VF1690 176 COG0583 LysR, Transcriptional regulator Transcription 59712152 Common - transcriptional regulator VF1545 176 COG0583 LysR, Transcriptional regulator Transcription 59711124 Common - TadB-like protein involved in pilus formation and/or protein secretion VF0517 75 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 59712737 Common - hypothetical membrane spanning protein VF2130 133 COG2860 COG2860, Predicted membrane protein Function unknown 59711662 Common - D-lactate dehydrogenase VF1055 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 59711811 Common - DNA gyrase subunit A VF1204 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 59710819 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase VF0212 86 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 59711859 Common - L-sulfolactate dehydrogenase VF1252 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 59711575 Common - beta-lactamase family protein VF0968 154 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 59712159 Common - thiosulfate reductase electron transport subunit VF1552 167 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 59711854 Nonpathogen - hypothetical protein VF1247 2 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 59711669 Common - adenylosuccinate synthetase VF1062 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 59710871 Common - fructose-1,6-bisphosphatase VF0264 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 59711105 Common - DNA polymerase III, psi subunit VF0498 14 COG3050 HolD, DNA polymerase III, psi subunit DNA replication, recombination, and repair 59710812 Common groEL chaperonin GroEL VF0205 246 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 59711014 Common - ornithine carbamoyltransferase VF0407 235 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 59710654 Common - hypothetical protein VF0047 36 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 59712640 Common - hypothetical bacteriophage protein VF2033 1 None None None 59712074 Common dnaK molecular chaperone DnaK VF1467 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 59712950 Common - transcriptional regulatory protein CpxR VF2343 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 59713141 Common - hypothetical protein VF2534 3 None None None 59711271 Common - transcriptional regulator, RpiR family VF0664 116 COG1737 RpiR, Transcriptional regulators Transcription 59712608 Common - hypothetical protein VF2001 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 59713052 Common - chorismate--pyruvate lyase VF2445 33 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 59711713 Common - hypothetical protein VF1106 149 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 59711867 Common - transcriptional regulator, TetR family VF1260 66 COG1309 AcrR, Transcriptional regulator Transcription 59713156 Common - sporulation-control protein VF2549 19 COG4326 Spo0M, Sporulation control protein General function prediction only 59711852 Common - hypothetical protein VF1245 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 59710833 Common - FKBP-type peptidyl-prolyl cis-trans isomerase FkpA VF0226 138 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 59712138 Common - ferrochelatase VF1531 141 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 59712148 Common - phosphohydrolase (MutT/nudix family protein) VF1541 36 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 59711899 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase VF1292 84 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 59712401 Common - hypothetical protein VF1794 18 COG3013 COG3013, Uncharacterized conserved protein Function unknown 59711414 Common nagA N-acetylglucosamine-6-phosphate deacetylase VF0807 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 59711837 Common - hypothetical protein VF1230 5 None None None 59711131 Common - sensor protein PhoQ VF0524 206 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59712236 Common - hypothetical protein VF1629 8 None None None 59712345 Common - 3-oxoacyl-(acyl carrier protein) synthase II VF1738 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 59712824 Common - cytochrome c1 VF2217 74 COG2857 CYT1, Cytochrome c1 Energy production and conversion 59710800 Common - UDP-2-acetamido-2,6-dideoxy-beta-L-talose 2-epimerase VF0193 154 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 59712279 Common - menaquinone-specific isochorismate synthase VF1672 222 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 59711179 Common - pili subunit PilA1 VF0572 40 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 59712584 Common - Protein YgiW precursor VF1977 22 COG3111 COG3111, Uncharacterized conserved protein Function unknown 59712484 Common flgB flagellar basal body rod protein FlgB VF1877 79 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 59713084 Common hslO Hsp33-like chaperonin VF2477 137 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 59712299 Common - colicin V production protein VF1692 107 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 59712637 Common - exodeoxyribonuclease VIII VF2030 9 None None None 59712428 Common - heme exporter protein D VF1821 8 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 59712533 Common - uracil permease VF1926 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 59711345 Common - xanthine-guanine phosphoribosyltransferase VF0738 61 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 59710735 Common - LSU ribosomal protein L33P VF0128 137 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 59712492 Common - hypothetical protein VF1885 10 None None None 59712922 Common - transcriptional repressor NsrR VF2315 139 COG1959 COG1959, Predicted transcriptional regulator Transcription 59711421 Common - esterase/lipase VF0814 147 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 59712043 Common - hypothetical protein VF1436 43 COG3304 COG3304, Predicted membrane protein Function unknown 59711944 Common - O-acetyltransferase (cell wall biosynthesis) VF1337 194 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 59711396 Common - phosphodiesterase VF0789 41 COG0622 COG0622, Predicted phosphoesterase General function prediction only 59710622 Common glyQ glycyl-tRNA synthetase subunit alpha VF0015 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 59711830 Common - TolR protein VF1223 10 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 59711563 Common - hypothetical protein VF0956 4 COG3790 COG3790, Predicted membrane protein Function unknown 59712054 Common - D-ribose transporter subunit RbsB VF1447 133 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 59711498 Common - DNA-binding transcriptional regulator HexR VF0891 105 COG1737 RpiR, Transcriptional regulators Transcription 59712117 Common - transcriptional regulator VF1510 175 COG0583 LysR, Transcriptional regulator Transcription 59710650 Common - transporter, drug/metabolite exporter family VF0043 82 COG2510 COG2510, Predicted membrane protein Function unknown 59710900 Common - isopropylmalate isomerase large subunit VF0293 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 59712724 Common - homoserine kinase VF2117 134 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 59711568 Common - TolA protein VF0961 8 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 59712797 Common - hypothetical protein VF2190 43 COG4582 COG4582, Uncharacterized protein conserved in bacteria Function unknown 59711169 Common - ribosome-associated factor Y VF0562 47 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 59710728 Common greB transcription elongation factor GreB VF0121 198 COG0782 GreA, Transcription elongation factor Transcription 59710740 Common - glycosyltransferase VF0133 219 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 59711142 Common recA recombinase A VF0535 240 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 59711174 Common - hypothetical protein VF0567 4 None None None 59712426 Common - heme chaperone--apocytochrome heme-lyase VF1819 147 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 59710747 Common - UDP-N-acetylglucosamine 4,6-dehydratase VF0140 136 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 59712591 Common - phosphate transport system permease protein PstA VF1984 222 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 59711657 Common - hypothetical protein VF1050 13 None None None 59711975 Common - membrane-bound lytic murein transglycosylase C precursor VF1368 129 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 59710954 Common - hypothetical protein VF0347 4 None None None 59711947 Common - hypothetical protein VF1340 2 None None None 59712329 Common - transcriptional activator protein MetR VF1722 175 COG0583 LysR, Transcriptional regulator Transcription 59712574 Common secD preprotein translocase subunit SecD VF1967 203 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 59710684 Common - 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase VF0077 22 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 59711444 Common - acetate kinase VF0837 162 COG0282 ackA, Acetate kinase Energy production and conversion 59713129 Common - transcriptional regulator, TetR family VF2522 101 COG1309 AcrR, Transcriptional regulator Transcription 59712096 Common - hypothetical protein VF1489 13 None None None 59711889 Common - membrane alanine aminopeptidase VF1282 161 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 59712661 Nonpathogen - hypothetical protein VF2054 5 None None None 59711804 Common - tyrosine-specific transport protein VF1197 35 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 59711638 Common - anthranilate phosphoribosyltransferase VF1031 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 59712432 Common - hypothetical protein VF1825 8 None None None 59711483 Common - hypothetical protein VF0876 3 None None None 59712104 Common - hypothetical protein VF1497 7 None None None 59712267 Common - hypothetical protein VF1660 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 59712711 Common - 5-formyltetrahydrofolate cyclo-ligase VF2104 188 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 59710737 Common - formamidopyrimidine-DNA glycosylase VF0130 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 59712127 Common - hypothetical protein VF1520 5 None None None 59710759 Common rfaD ADP-L-glycero-D-mannoheptose-6-epimerase VF0152 218 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 59711376 Common - peptide release factor-glutamine N5-methyltransferase VF0769 219 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 59711682 Common - transporter, LysE family VF1075 74 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 59710679 Common glpT sn-glycerol-3-phosphate transporter VF0072 81 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 59711473 Common - hypothetical protein VF0866 1 None None None 59711188 Common recC exonuclease V subunit gamma VF0581 65 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 59710948 Common uvrA excinuclease ABC subunit A VF0341 241 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 59710923 Common - transporter, drug/metabolite exporter family VF0316 77 COG2962 RarD, Predicted permeases General function prediction only 59712110 Common - methyl-accepting chemotaxis protein VF1503 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711532 Common - ribonuclease T VF0925 67 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 59712668 Common - hypothetical protein VF2061 65 COG2391 COG2391, Predicted transporter component General function prediction only 59711828 Common - hemin transport system permease protein HmuU VF1221 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 59712508 Common - hypothetical protein VF1901 7 None None None 59711495 Common - short-chain alcohol dehydrogenase VF0888 25 COG3007 COG3007, Uncharacterized paraquat-inducible protein B Function unknown 59711233 Common - hypothetical protein VF0626 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 59712946 Common - lysine 2,3-aminomutase VF2339 126 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 59712323 Common - transcriptional regulator, AraC family VF1716 108 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 59712178 Common torD chaperone protein TorD VF1571 32 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 59712064 Common - thermostable carboxypeptidase 1 VF1457 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 59710704 Common - hypothetical protein VF0097 11 None None None 59711033 Common - hypothetical protein VF0426 13 None None None 59711072 Common - virulence factor MviN VF0465 196 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 59710910 Common - hypothetical protein VF0303 4 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 59712414 Common - hypothetical protein VF1807 74 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 59711219 Common - hypothetical protein VF0612 30 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 59713163 Common - acetolactate synthase 2 catalytic subunit VF2556 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 59712672 Common - nucleoside permease NupC VF2065 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 59712409 Common - hypothetical protein VF1802 31 COG3101 COG3101, Uncharacterized protein conserved in bacteria Function unknown 59710753 Common - oxidoreductase VF0146 155 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 59711055 Common xerD site-specific tyrosine recombinase XerD VF0448 231 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 59713150 Common def peptide deformylase VF2543 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 59711114 Common deoD purine nucleoside phosphorylase VF0507 94 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 59712224 Common - hypothetical protein VF1617 3 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 59713089 Common - hydrolase (HAD superfamily) VF2482 119 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 59713016 Common - minor curlin subunit CsgB VF2409 17 None None None 59711261 Common - hypothetical protein VF0654 3 None None None 59711279 Common - urease accessory protein UreE VF0672 63 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 59713048 Common - hypothetical protein VF2441 32 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 59711932 Nonpathogen - hypothetical protein VF1325 1 None None None 59711286 Common - oligopeptide transport system permease protein OppC VF0679 217 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 59712243 Common - preprotein translocase subunit-like protein VF1636 10 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 59712905 Common - multimodular transpeptidase-transglycosylase PBP 1A VF2298 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 59711152 Common - S-ribosylhomocysteinase VF0545 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 59712709 Common - hypothetical protein VF2102 32 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 59712289 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein VF1682 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 59711001 Common - toluene tolerance protein TTG2A VF0394 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 59711361 Common - hypothetical protein VF0754 23 None None None 59711206 Common - SecY interacting protein Syd VF0599 19 None None None 59711780 Common - hypothetical protein VF1173 1 None None None 59711007 Common - toluene tolerance protein TTG2F VF0400 75 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 59713079 Common - general secretion pathway protein F VF2472 147 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 59710993 Common - ribosome-associated factor Y VF0386 134 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 59712690 Common acpS 4'-phosphopantetheinyl transferase VF2083 166 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 59710828 Common - glutathione-regulated potassium-efflux system protein KefB VF0221 154 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 59711870 Common - mercuric reductase VF1263 88 COG0398 COG0398, Uncharacterized conserved protein Function unknown 59711021 Common - hypothetical membrane spanning protein VF0414 90 COG0795 COG0795, Predicted permeases General function prediction only 59710860 Common rplR 50S ribosomal protein L18 VF0253 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 59712011 Common - molybdenum transport ATP-binding protein ModC VF1404 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 59711453 Common - acyl carrier protein VF0846 47 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 59712514 Common - ferredoxin-type protein NapF VF1907 41 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 59712908 Common - dihydrolipoamide dehydrogenase VF2301 239 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 59712770 Common - ATP-dependent RNA helicase HrpB VF2163 134 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 59711061 Common - transcriptional regulator VF0454 173 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 59711624 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase VF1017 215 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 59711634 Common trpA tryptophan synthase subunit alpha VF1027 213 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 59711877 Common - cyclohexadienyl dehydratase precursor VF1270 150 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 59712014 Common - hypothetical protein VF1407 9 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 59712080 Common - hypothetical protein VF1473 5 None None None 161986798 Common yebU rRNA (cytosine-C(5)-)-methyltransferase RsmF VF1274 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 59711514 Common - recombination factor protein RarA VF0907 212 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 59712688 Common rumA 23S rRNA 5-methyluridine methyltransferase VF2081 202 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 59710932 Common - hypothetical protein VF0325 21 COG3495 COG3495, Uncharacterized protein conserved in bacteria Function unknown 59711041 Common - hypothetical protein VF0434 129 COG1678 COG1678, Putative transcriptional regulator Transcription 59710970 Common - general secretion pathway protein F VF0363 151 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 161986793 Common fxsA FxsA VF2352 69 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 59712122 Common - hypothetical protein VF1515 178 COG3614 COG3614, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 59712699 Common - sigma-E factor negative regulatory protein VF2092 27 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 59710618 Common recF recombination protein F VF0011 166 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 59711247 Common - hypothetical protein VF0640 48 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 59713070 Common - ADP-ribose pyrophosphatase VF2463 131 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 59712163 Common - phospholipase A1 VF1556 51 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 59711330 Common - 16S rRNA m(2)G 966 methyltransferase VF0723 79 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 59711386 Common - SMR/MUTS family protein VF0779 98 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 59711841 Common - hemin receptor VF1234 131 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 59711957 Common - hypothetical protein VF1350 180 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 59711262 Common - endochitinase VF0655 68 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 59711961 Common - ATP-dependent DNA helicase recG VF1354 56 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 59712615 Common - tail sheath protein VF2008 21 COG4386 COG4386, Mu-like prophage tail sheath protein gpL General function prediction only 59710981 Common - rod shape-determining protein MreD VF0374 47 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 59710907 Common - hypothetical protein VF0300 5 COG3137 COG3137, Putative salt-induced outer membrane protein Cell envelope biogenesis, outer membrane 59711120 Common - general secretion pathway protein D VF0513 139 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 59711997 Common - carbohydrate binding domain protein VF1390 23 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 59711964 Common - formate dehydrogenase, cytochrome B556 subunit VF1357 45 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 59712862 Common - hypothetical protein VF2255 4 None None None 59712939 Common - transporter, drug/metabolite exporter family VF2332 22 COG2510 COG2510, Predicted membrane protein Function unknown 59711401 Common hemH ferrochelatase VF0794 158 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 59711649 Nonpathogen - hypothetical protein VF1042 1 None None None 59712504 Common - glucose-specific PTS system component VF1897 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 59712199 Common - hypothetical protein VF1592 59 COG2850 COG2850, Uncharacterized conserved protein Function unknown 59710663 Common - ATP-dependent RNA helicase RhlB VF0056 210 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 59710884 Common - farnesyl pyrophosphate synthetase VF0277 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 59712467 Common fliD flagellar capping protein VF1860 91 COG1345 FliD, Flagellar capping protein Cell motility and secretion 59713050 Common - glycerol-3-phosphate acyltransferase VF2443 48 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 59710945 Common - aspartate kinase III VF0338 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 59711237 Common hisS histidyl-tRNA synthetase VF0630 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59712726 Common - ribonuclease activity regulator protein RraA VF2119 89 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 59711252 Common - glutathione-dependent formaldehyde dehydrogenase VF0645 194 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 59710760 Common - cleavage and polyadenylation VF0153 120 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 59713143 Common - SUA5 protein VF2536 238 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 59712606 Common - small protein A VF1999 63 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 59712626 Nonpathogen - hypothetical protein VF2019 1 None None None 59710611 Common rnpA ribonuclease P VF0004 79 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 59712454 Common - flagellar hook-length control protein VF1847 31 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 59711806 Common - ferredoxin VF1199 48 COG0633 Fdx, Ferredoxin Energy production and conversion 59712810 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase VF2203 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 59711203 Common - diguanylate cyclase/phosphodiesterase domain 1 (GGDEF) VF0596 171 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 59711774 Common - exonuclease subunit SbcD VF1167 104 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 59711794 Common - hypothetical protein VF1187 2 None None None 59712447 Common fliR flagellar biosynthesis protein FliR VF1840 116 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 59711116 Common serB phosphoserine phosphatase VF0509 151 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 59712051 Common - high affinity ribose transport protein RbsD VF1444 48 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 59711538 Common - electron transport complex protein RnfG VF0931 56 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 59712047 Nonpathogen - hypothetical protein VF1440 1 None None None 59712835 Common - DNA topoisomerase IV subunit B VF2228 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 59711129 Common - TadG-like protein VF0522 5 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 59712850 Common - general secretion pathway protein A VF2243 74 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 59710826 Common - glutathione-regulated potassium-efflux system ancillary protein KefG VF0219 67 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 59712272 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase VF1665 161 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 59711543 Common - excinuclease ABC subunit B VF0936 232 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 59711135 Common - DNA repair protein RadA VF0528 213 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 59710968 Common - tetratricopeptide repeat family protein VF0361 21 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 59712058 Common - nuclease VF1451 48 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 59710839 Common - elongation factor G VF0232 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 59711744 Common - putative lipoprotein VF1137 40 COG3417 FlgN, Collagen-binding surface adhesin SpaP (antigen I/II family) General function prediction only 59712806 Common - cell division protein FtsQ VF2199 61 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 59711268 Common - hypothetical protein VF0661 6 None None None 59711653 Nonpathogen - hypothetical protein VF1046 3 None None None 59711660 Common - sensory transduction protein kinase VF1053 158 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 59712930 Common hfq RNA-binding protein Hfq VF2323 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 59711608 Common - hypothetical protein VF1001 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 59711919 Common - hypothetical protein VF1312 6 None None None 59712472 Common - flagellin VF1865 125 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 59712713 Common - D-3-phosphoglycerate dehydrogenase VF2106 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 59711580 Common - glutamate--cysteine ligase VF0973 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 59712774 Common - poly(A) polymerase VF2167 66 None None None 59711300 Common - hypothetical protein VF0693 2 COG3895 COG3895, Predicted periplasmic protein General function prediction only 59710863 Common - LSU ribosomal protein L15P VF0256 168 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 59711067 Common thyA thymidylate synthase VF0460 136 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 59712126 Common - hypothetical protein VF1519 6 None None None 59711879 Common - elongation factor P VF1272 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 59710716 Common - transporter, drug/metabolite exporter family VF0109 136 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 59710696 Common - hypothetical outer membrane protein VF0089 4 COG3650 COG3650, Predicted membrane protein Function unknown 59710991 Common - hypothetical protein VF0384 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 59711322 Common motB flagellar motor protein MotB VF0715 152 COG1360 MotB, Flagellar motor protein Cell motility and secretion 59711291 Common metQ DL-methionine transporter substrate-binding subunit VF0684 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 59712654 Nonpathogen - hypothetical protein VF2047 2 None None None 59713177 Common - F0F1 ATP synthase subunit A VF2570 207 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 59712025 Common - hypothetical protein VF1418 90 COG1262 COG1262, Uncharacterized conserved protein Function unknown 59712840 Common tolC outer membrane channel protein VF2233 139 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 59710767 Common - WbfD protein VF0160 12 None None None 59711589 Common - transporter, drug/metabolite exporter family VF0982 27 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 59712847 Common - low-affinity inorganic phosphate transporter VF2240 176 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 59711423 Common - phosphoglucomutase VF0816 232 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 59711144 Common - aspartate kinase VF0537 233 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 59711242 Common - hypothetical protein VF0635 10 None None None 59711573 Common - hypothetical protein VF0966 4 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 59710638 Common - chloride channel protein VF0031 124 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 59710771 Common - Protein tyrosine phosphatase VF0164 126 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 59712707 Common - 2-octaprenyl-6-methoxyphenol hydroxylase VF2100 132 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 59710652 Common - RmuC family protein VF0045 91 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 59713088 Common - lysophospholipase L2 VF2481 91 COG2267 PldB, Lysophospholipase Lipid metabolism 59710988 Common - peptidase PmbA VF0381 158 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 59711477 Common - hypothetical protein VF0870 9 COG3153 COG3153, Predicted acetyltransferase General function prediction only 59711614 Common - primosomal replication protein N' VF1007 17 COG3923 PriC, Primosomal replication protein N'' DNA replication, recombination, and repair 59712731 Common - glutamate synthase [NADPH] large chain VF2124 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 59713020 Common - DNA-directed RNA polymerase beta chain VF2413 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 59711106 Common - ribosomal-protein-S18-alanine acetyltransferase VF0499 177 COG0456 RimI, Acetyltransferases General function prediction only 59710810 Common - Na(+) driven multidrug efflux pump VF0203 172 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 59712665 Common - predicted lysine/cadaverine transporter VF2058 170 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 59710916 Common - hypothetical protein VF0309 2 None None None 59711640 Common - anthranilate synthase component I VF1033 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 59712523 Common - hypothetical protein VF1916 1 None None None 59711971 Common - hypothetical protein VF1364 9 None None None 59710817 Common - transcriptional regulator VF0210 21 COG3074 COG3074, Uncharacterized protein conserved in bacteria Function unknown 59711667 Common - peptidase T VF1060 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 59712006 Common - glycosyltransferase involved in cell wall biogenesis VF1399 177 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 59712642 Nonpathogen - hypothetical protein VF2035 1 None None None 59711521 Common - methionine sulfoxide reductase B VF0914 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 59711857 Common - hypothetical protein VF1250 21 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 59712076 Common - DNA-binding transcriptional regulator VF1469 21 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 59712078 Common - hypothetical protein VF1471 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 59711251 Common - S-formylglutathione hydrolase VF0644 94 COG0627 COG0627, Predicted esterase General function prediction only 59712353 Common - septum formation protein Maf VF1746 191 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 59711227 Common hscB co-chaperone HscB VF0620 55 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 59711715 Common - chaperone protein DnaJ VF1108 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 59711787 Common - fumarate hydratase VF1180 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 59710855 Common rplX 50S ribosomal protein L24 VF0248 178 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 59712913 Common argC N-acetyl-gamma-glutamyl-phosphate reductase VF2306 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 59711723 Nonpathogen - hypothetical protein VF1116 1 COG3710 CadC, DNA-binding winged-HTH domains Transcription 59712739 Common - acriflavin resistance plasma membrane protein VF2132 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 59711283 Common - urease accessory protein UreD VF0676 80 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 59712136 Common - hypothetical protein VF1529 3 None None None 59712154 Common - aspartate racemase VF1547 86 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 59711706 Common - beta-lactamase VF1099 52 COG2367 PenP, Beta-lactamase class A Defense mechanisms 59712314 Common - ribonuclease D VF1707 121 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 59712955 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase VF2348 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 59712596 Common rdgC recombination associated protein VF1989 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 59712375 Common - hypothetical protein VF1768 2 None None None 59712339 Common - glucose-specific PTS system IIBC components VF1732 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 59711921 Common - hypothetical protein VF1314 12 COG5473 COG5473, Predicted integral membrane protein Function unknown 59710796 Common - hypothetical protein VF0189 5 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 59711712 Common - transporter VF1105 96 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 59710802 Common - UDP-N-acetyl-D-quinovosamine 4-epimerase VF0195 218 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 59712307 Common - 3-oxoacyl-[acyl-carrier-protein] synthase VF1700 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 59713098 Nonpathogen - hypothetical protein VF2491 1 None None None 59711378 Common - transcriptional regulator VF0771 54 COG2912 COG2912, Uncharacterized conserved protein Function unknown 59711277 Common - urease accessory protein UreG VF0670 156 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 59712290 Common - hypothetical cytosolic protein VF1683 38 COG3148 COG3148, Uncharacterized conserved protein Function unknown 59711508 Common - cysteine/glutathione ABC transporter membrane/ATP-binding component VF0901 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 59712973 Common - high-affinity zinc uptake system protein ZnuA precursor VF2366 117 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 59711431 Common - dihydrolipoamide acetyltransferase VF0824 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 59710751 Common - sialic acid biosynthesis protein NeuD VF0144 104 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 59712494 Common gltX glutamyl-tRNA synthetase VF1887 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 59713136 Common - DNA-binding transcriptional regulator IlvY VF2529 188 COG0583 LysR, Transcriptional regulator Transcription 59710823 Common - predicted hydrolase VF0216 68 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 59711928 Common - transcriptional regulators, LysR family VF1321 166 COG0583 LysR, Transcriptional regulator Transcription 59711791 Common - acriflavin resistance plasma membrane protein VF1184 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 59710848 Common rplV 50S ribosomal protein L22 VF0241 217 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 59712381 Common - hypothetical protein VF1774 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 59712393 Common - adenylosuccinate lyase VF1786 239 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 59713114 Common - dihydroorotase VF2507 35 COG3964 COG3964, Predicted amidohydrolase General function prediction only 59712752 Common - N-acetylglucosamine kinase VF2145 55 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 59711077 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase VF0470 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 59712915 Common - phosphoenolpyruvate carboxylase VF2308 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 59711472 Common - cardiolipin synthetase VF0865 137 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 59712094 Common purT phosphoribosylglycinamide formyltransferase 2 VF1487 224 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 59711167 Common - NTPase VF0560 36 COG1986 COG1986, Uncharacterized conserved protein Function unknown 59711485 Common - multidrug resistance protein A VF0878 161 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 59710783 Common - 2-dehydro-3-deoxyphosphooctonate aldolase VF0176 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 59713120 Common - cyclic nucleotide binding protein/2 CBS domains VF2513 110 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 59712344 Common - 4-amino-4-deoxychorismate lyase VF1737 170 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 59710832 Common - vegetatible incompatibility protein HET-E-1 VF0225 47 COG2319 COG2319, FOG: WD40 repeat General function prediction only 59712092 Common - cytidine deaminase VF1485 46 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 59710927 Common - sulfate adenylyltransferase subunit 2 VF0320 138 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 59710798 Common - UDP-2-acetamido-2,6-dideoxy-alpha-D-xylo-4-hexulose 3,5-epimerase VF0191 190 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 59710956 Common - chain length regulator VF0349 100 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 59711916 Common - transcriptional regulator VF1309 98 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 59712679 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase VF2072 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 59712434 Common - CheW-like domain VF1827 14 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 59712610 Common - hypothetical protein VF2003 9 COG3617 COG3617, Prophage antirepressor Transcription 59712677 Common surE stationary phase survival protein SurE VF2070 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 59711186 Common - transcriptional regulators, LysR family VF0579 193 COG0583 LysR, Transcriptional regulator Transcription 59713011 Common - anti-RNA polymerase sigma 70 factor VF2404 24 COG3160 Rsd, Regulator of sigma D Transcription 59712395 Common - hypothetical protein VF1788 1 None None None 59712403 Common rrmA 23S rRNA methyltransferase A VF1796 62 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 59711684 Common - NirV precursor VF1077 109 COG1262 COG1262, Uncharacterized conserved protein Function unknown 59712681 Common - cell division protein FtsB VF2074 64 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 59712957 Common - rhodanese-related sulfurtransferase VF2350 116 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 59711308 Common - riboflavin synthase subunit alpha VF0701 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 59711299 Common - oligopeptide transport ATP-binding protein OppF VF0692 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 59711704 Common - BAX protein VF1097 31 COG2992 Bax, Uncharacterized FlgJ-related protein General function prediction only 59712882 Common - DNA-binding transcriptional regulator CytR VF2275 128 COG1609 PurR, Transcriptional regulators Transcription 59712764 Common - glycerate kinase VF2157 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 59713055 Common glpE thiosulfate sulfurtransferase VF2448 139 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 59710946 Common - serine--pyruvate aminotransferase VF0339 166 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 59712941 Common - fumarate reductase flavoprotein subunit VF2334 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 59710742 Common - ADP-heptose--LPS heptosyltransferase III VF0135 111 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 59712839 Common - ADP-ribose pyrophosphatase VF2232 110 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 59711955 Common - hypothetical cytosolic protein VF1348 6 None None None 59712198 Common pflA pyruvate formate lyase-activating enzyme 1 VF1591 112 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 59712231 Common - hypothetical protein VF1624 14 COG2716 GcvR, Glycine cleavage system regulatory protein Amino acid transport and metabolism 59711172 Common - hypothetical protein VF0565 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 161986797 Common - flagellin VF1862 125 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 59711850 Common - hypothetical protein VF1243 7 None None None 59711893 Common - hypothetical protein VF1286 17 None None None 59711835 Common - hypothetical protein VF1228 23 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 59710721 Common ompR osmolarity response regulator VF0114 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 59712066 Common - translation initiation inhibitor VF1459 181 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 59711550 Common - molybdopterin converting factor, large subunit VF0943 162 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 59712971 Common - NADH dehydrogenase VF2364 204 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 59712421 Common - hypothetical membrane spanning protein VF1814 40 COG3647 COG3647, Predicted membrane protein Function unknown 59711133 Common - transcriptional regulator VF0526 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 59712238 Common - DNA-binding protein H-NS VF1631 28 COG2916 Hns, DNA-binding protein H-NS General function prediction only 59711217 Common - hypothetical protein VF0610 12 None None None 59711122 Common - ATPase involved in chromosome partitioning VF0515 12 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 59712280 Common - aminotransferase AlaT VF1673 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 59710791 Common - CDP-4-dehydro-6-deoxy-D-glucose 3-dehydratase VF0184 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 59711416 Common - glutaminyl-tRNA synthetase VF0809 244 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 59712854 Common - dihydroneopterin aldolase VF2247 116 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 59712172 Common - cobalt transport ATP-binding protein CbiO VF1565 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 59713165 Common - branched-chain amino acid aminotransferase VF2558 220 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 59710670 Common - HemY protein VF0063 49 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 59712962 Common - universal stress protein A VF2355 26 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 59711150 Common - glutamate--cysteine ligase VF0543 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 59712084 Common - tetratricopeptide repeat family protein VF1477 96 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 59712543 Common rnhA ribonuclease H VF1936 176 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 59711063 Common - dinucleoside polyphosphate hydrolase VF0456 115 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 59711525 Common - acetaldehyde dehydrogenase [acetylating] VF0918 197 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 59712531 Common - hypothetical protein VF1924 12 COG3308 COG3308, Predicted membrane protein Function unknown 59712045 Common - hypothetical protein VF1438 7 None None None 59711888 Common - hypothetical protein VF1281 2 None None None 59712983 Common - hypothetical protein VF2376 52 COG4327 COG4327, Predicted membrane protein Function unknown 59711741 Common - HIT family hydrolase VF1134 232 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 59711082 Common - OmpU, outer membrane protein VF0475 40 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 59712635 Nonpathogen - hypothetical protein VF2028 1 None None None 59711942 Common - metal-dependent phosphohydrolase VF1335 64 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 59712519 Common - hypothetical protein VF1912 11 COG4104 COG4104, Uncharacterized conserved protein Function unknown 59710843 Common - LSU ribosomal protein L3P VF0236 242 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 59711952 Common - ribosomal-protein-serine acetyltransferase VF1345 126 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 59712849 Common - general secretion pathway protein B VF2242 8 None None None 59712670 Common - homoserine O-succinyltransferase VF2063 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 59712270 Common - hypothetical protein VF1663 34 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 59712056 Common - transcriptional regulator, LacI family VF1449 128 COG1609 PurR, Transcriptional regulators Transcription 59712404 Nonpathogen - hypothetical protein VF1797 1 None None None 59713008 Common - protein YhgI VF2401 28 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 59712572 Common - putative structural protein VF1965 17 COG5324 COG5324, Uncharacterized conserved protein Function unknown 59711599 Common - IcmF protein VF0992 47 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 59712016 Common - hypothetical cytosolic protein VF1409 33 COG3148 COG3148, Uncharacterized conserved protein Function unknown 59712694 Common rnc ribonuclease III VF2087 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 59711089 Common - hypothetical protein VF0482 176 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 59712119 Common - thiopurine S-methyltransferase VF1512 35 None None None 59712692 Common recO DNA repair protein RecO VF2085 101 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 59711862 Common - transcriptional repressor VF1255 127 COG1609 PurR, Transcriptional regulators Transcription 59710959 Common - undecaprenyl-phosphate beta-glucosephosphotransferase VF0352 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 59713072 Common - general secretion pathway protein M VF2465 21 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 59712112 Common - methyltransferase VF1505 137 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 59710979 Common - rod shape-determining protein MreB VF0372 234 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 59711626 Common - bifunctional phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphatase protein VF1019 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 59710757 Common - hypothetical protein VF0150 3 None None None 161986791 Common - predicted kinase VF2552 50 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 59712351 Common rpmF 50S ribosomal protein L32 VF1744 66 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 59712033 Common - tetratricopeptide repeat family protein VF1426 47 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 59711621 Common - histidinol-phosphate aminotransferase VF1014 232 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 59711848 Common - phospho-2-dehydro-3-deoxyheptonate aldolase VF1241 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 59712579 Common - isocitrate lyase VF1972 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 59711872 Nonpathogen - hypothetical protein VF1265 1 None None None 59712449 Common fliP flagellar biosynthesis protein FliP VF1842 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 59710649 Common - hypothetical protein VF0042 1 None None None 59712209 Common - UDP-2,3-diacylglucosamine hydrolase VF1602 82 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 59710665 Common rho transcription termination factor Rho VF0058 202 COG1158 Rho, Transcription termination factor Transcription 59712259 Common - hypothetical protein VF1652 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711347 Common - gamma-glutamyl kinase VF0740 191 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 59712486 Common - chemotaxis protein CheV VF1879 188 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 59710718 Common - ribonuclease PH VF0111 195 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 59712361 Common metG methionyl-tRNA synthetase VF1754 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59711591 Common - hypothetical protein VF0984 2 None None None 59712211 Common - protein translocase subunit SecA VF1604 87 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 59710625 Common - NADH dehydrogenase subunit II-related protein VF0018 2 None None None 59711869 Common - glutaredoxin VF1262 43 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 59711549 Common moaD molybdopterin synthase small subunit VF0942 63 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 59711534 Common - hypothetical protein VF0927 3 None None None 59710675 Common uvrD DNA-dependent helicase II VF0068 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 59712165 Common - NAD-dependent malic enzyme VF1558 202 COG0281 SfcA, Malic enzyme Energy production and conversion 59712822 Common - ClpXP protease specificity-enhancing factor VF2215 64 COG2969 SspB, Stringent starvation protein B General function prediction only 59711655 Nonpathogen - hypothetical protein VF1048 1 None None None 59710861 Common - SSU ribosomal protein S5P VF0254 248 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 59711000 Common - sodium-calcium exchanger VF0393 136 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 59711098 Common - lipoprotein NlpI VF0491 39 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 59712948 Common fieF ferrous iron efflux protein F VF2341 209 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 59713046 Common - soluble pyridine nucleotide transhydrogenase VF2439 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 59710711 Common - bifunctional (p)ppGpp synthetase II/ guanosine-3',5'-bis pyrophosphate 3'-pyrophosphohydrolase VF0104 208 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 59711910 Common - hypothetical protein VF1303 23 COG3198 COG3198, Uncharacterized protein conserved in bacteria Function unknown 59712301 Common - dihydrofolate synthase VF1694 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 59713152 Common - 16S rRNA m(5)C 967 methyltransferase VF2545 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 59711005 Common - toluene tolerance protein TTG2D VF0398 14 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 59713038 Nonpathogen - hypothetical protein VF2431 1 None None None 59713175 Common - F0F1 ATP synthase subunit B VF2568 161 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 59711290 Common - putative transcriptional regulator VF0683 87 COG1720 COG1720, Uncharacterized conserved protein Function unknown 59712700 Common - RNA polymerase sigma factor RpoE VF2093 168 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 59710765 Common - hypothetical protein VF0158 13 None None None 59711468 Common - heat shock protein HslJ VF0861 9 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 59711702 Common - transcriptional regulators, LysR family VF1095 180 COG0583 LysR, Transcriptional regulator Transcription 59711995 Common - dTDP-glucose 4,6-dehydratase VF1388 74 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 59711091 Common - hypothetical protein VF0484 179 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 59712497 Common ligA NAD-dependent DNA ligase LigA VF1890 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 59712318 Common - hypothetical protein VF1711 2 None None None 59712751 Common - endochitinase VF2144 10 None None None 59713104 Common - hypothetical protein VF2497 6 None None None 59711368 Common - GTP-binding protein VF0761 216 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 59711493 Common - hypothetical secreted protein VF0886 45 COG5621 COG5621, Predicted secreted hydrolase General function prediction only 59711384 Common - methyl-accepting chemotaxis protein VF0777 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59711977 Common - pyrrolidone-carboxylate peptidase VF1370 56 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 59712200 Common - oligopeptide transport ATP-binding protein OppF VF1593 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 59712179 Common - transcriptional regulator, LacI family VF1572 128 COG1609 PurR, Transcriptional regulators Transcription 59712790 Common - N-acetyl-anhydromuranmyl-L-alanine amidase VF2183 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 59711425 Common gltA type II citrate synthase VF0818 194 COG0372 GltA, Citrate synthase Energy production and conversion 59711693 Common - hypothetical protein VF1086 8 COG3710 CadC, DNA-binding winged-HTH domains Transcription 59711317 Common - hypothetical protein VF0710 7 COG1359 COG1359, Uncharacterized conserved protein Function unknown 59711766 Common asnC asparaginyl-tRNA synthetase VF1159 228 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 59711363 Common - magnesium and cobalt efflux protein CorC VF0756 218 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 59711288 Common - oligopeptide-binding protein OppA VF0681 184 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 59710805 Common - UDP-glucose 6-dehydrogenase VF0198 189 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 59710976 Common - hypothetical protein VF0369 11 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 59711281 Common - urease beta subunit VF0674 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 59713140 Common - O-acetyltransferase (cell wall biosynthesis) VF2533 188 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 59712778 Common - ABC transporter permease protein VF2171 144 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 59712817 Common - corrin/porphyrin methyltransferase VF2210 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 59711333 Common - Na(+)-translocating NADH-quinone reductase subunit B VF0726 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 59711038 Common - pili retraction protein PilT VF0431 219 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 59712799 Common - mutator MutT protein (7,8-dihydro-8-oxoguanine-triphosphatase) VF2192 165 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 59711035 Common - integral membrane protein VF0428 93 COG0762 COG0762, Predicted integral membrane protein Function unknown 59712949 Common - periplasmic protein CpxP VF2342 17 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 59710780 Common - hypothetical protein VF0173 6 None None None 59712156 Common - thiol:disulfide interchange protein TlpA VF1549 132 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 59712628 Nonpathogen - hypothetical protein VF2021 1 None None None 59712979 Common - D-fructose-6-phosphate amidotransferase VF2372 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 59711151 Common - hypothetical protein VF0544 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 59710982 Common maf Maf-like protein VF0375 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 59712333 Common - hypothetical protein VF1726 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 59712189 Common - periplasmic component of efflux system VF1582 175 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 59712292 Common recR recombination protein RecR VF1685 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 59711266 Common - ribosomal protein S6 modification protein VF0659 39 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 59712507 Common - COME operon protein 3 VF1900 12 None None None 59713158 Common - hypothetical protein VF2551 79 COG0348 NapH, Polyferredoxin Energy production and conversion 59711334 Common - Na(+)-translocating NADH-quinone reductase subunit C VF0727 48 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 59712916 Common metF 5,10-methylenetetrahydrofolate reductase VF2309 151 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 59712312 Common - cell division inhibitor MinD VF1705 138 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 59712153 Common - anaerobic C4-dicarboxylate transporter VF1546 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 59711834 Common - hypothetical protein VF1227 18 COG3721 HugX, Putative heme iron utilization protein Inorganic ion transport and metabolism 59711306 Common - hypothetical protein VF0699 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 59711695 Common - anaerobic C4-dicarboxylate transporter VF1088 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 59712715 Common - mechanosensitive ion channel VF2108 207 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 59710699 Common - adenosine deaminase VF0092 109 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 59711759 Common - heat shock protein HtpX VF1152 188 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 59713134 Common - hypothetical protein VF2527 14 None None None 59713161 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase VF2554 29 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 59711249 Common - translation initiation inhibitor VF0642 177 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 59712605 Common - recombination and repair protein VF1998 202 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 59713122 Common - glycine betaine transporter VF2515 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 59711789 Common - acriflavin resistance periplasmic protein VF1182 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 59712474 Common flgL flagellar hook-associated protein FlgL VF1867 81 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 59710709 Common - acetyltransferase VF0102 62 COG2153 ElaA, Predicted acyltransferase General function prediction only 59711178 Common - pili retraction protein PilT VF0571 2 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 59713126 Common - dipeptide transport ATP-binding protein DppD VF2519 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 59712815 Common - cell division protein FtsL VF2208 35 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 59711999 Nonpathogen - hypothetical protein VF1392 1 None None None 59712745 Common - two-component sensor histidine kinase VF2138 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59711015 Common - arginine deiminase VF0408 53 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 59711506 Common - phosphoserine aminotransferase VF0899 115 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 59711502 Common - hypothetical protein VF0895 27 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 59711127 Common - TadE-like protein VF0520 4 None None None 59711917 Common - universal stress protein UspE VF1310 41 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 59713167 Common - threonine dehydratase VF2560 208 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 59711240 Common engA GTP-binding protein EngA VF0633 238 COG1160 COG1160, Predicted GTPases General function prediction only 59710626 Common - hypothetical transcriptional regulatory protein VF0019 91 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 59712203 Common oppB oligopeptide transporter permease VF1596 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 59711716 Common - hypothetical protein VF1109 6 None None None 59712442 Common - flagellar synthesis regulator FleN VF1835 152 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 59712528 Common - transporter VF1921 137 COG0628 PerM, Predicted permease General function prediction only 59711826 Common - hypothetical protein VF1219 40 COG4097 COG4097, Predicted ferric reductase Inorganic ion transport and metabolism 59711375 Common prfA peptide chain release factor 1 VF0768 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 59711924 Common potC spermidine/putrescine ABC transporter membrane protein VF1317 216 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 59711666 Common - basic endochitinase VF1059 19 COG3979 COG3979, Uncharacterized protein contain chitin-binding domain type 3 General function prediction only 59712553 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha VF1946 193 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 59712803 Common - cell division protein FtsZ VF2196 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 59712942 Common - fumarate reductase iron-sulfur subunit VF2335 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 59711717 Common - hypothetical protein VF1110 1 None None None 59711989 Common - ribosomal-protein-alanine acetyltransferase VF1382 57 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 59710640 Common - thiamin-phosphate pyrophosphorylase VF0033 205 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 59712646 Common - hypothetical protein VF2039 6 None None None 59712878 Common - maltose operon periplasmic protein precursor VF2271 10 None None None 59710637 Nonpathogen - hypothetical protein VF0030 1 None None None 59712131 Nonpathogen - hypothetical protein VF1524 1 None None None 59711535 Common - lactoylglutathione lyase VF0928 131 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 59711479 Common - methyl-accepting chemotaxis protein VF0872 96 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59712220 Common - phosphate transport ATP-binding protein PstB VF1613 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 59711570 Common - peptidoglycan-associated lipoprotein VF0963 151 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 59710772 Common - chain length regulator (capsular polysaccharide biosynthesis) VF0165 156 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 59711983 Common - hypothetical protein VF1376 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 59711297 Common - oligopeptide-binding protein OppA VF0690 165 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 59710844 Common rplD 50S ribosomal protein L4 VF0237 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 59711239 Common - outer membrane protein assembly complex subunit YfgL VF0632 122 COG1520 COG1520, FOG: WD40-like repeat Function unknown 59711018 Common valS valyl-tRNA synthetase VF0411 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59712795 Common - type 4 prepilin peptidase VF2188 138 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 59713056 Common - RNA polymerase sigma-32 factor VF2449 146 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 59712733 Common - hypothetical protein VF2126 21 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 59711814 Common - putative chaperone VF1207 206 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 59710889 Common - hypothetical protein VF0282 21 COG2966 COG2966, Uncharacterized conserved protein Function unknown 59712644 Common - transcriptional regulator, Cro/CI family VF2037 60 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 59710882 Common - arginine repressor VF0275 73 COG1438 ArgR, Arginine repressor Transcription 59712864 Common - hypothetical protein VF2257 2 None None None 59711158 Common trmD tRNA (guanine-N(1)-)-methyltransferase VF0551 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 59712060 Common - hypothetical protein VF1453 1 None None None 59711906 Common - cytochrome c oxidase polypeptide I VF1299 151 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 59712541 Common - ferredoxin-dependent glutamate synthase VF1934 12 None None None 59712040 Common - hypothetical protein VF1433 5 COG1433 COG1433, Uncharacterized conserved protein Function unknown 59712855 Common - hypothetical protein VF2248 170 COG0344 COG0344, Predicted membrane protein Function unknown 59710658 Common - Sec-independent protein translocase protein TatC VF0051 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 59711863 Common - 3',5'-cyclic-nucleotide phosphodiesterase VF1256 19 COG5212 PDE1, Low-affinity cAMP phosphodiesterase Signal transduction mechanisms 59711222 Common - RRNA methylase, SpoU family VF0615 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 59711902 Common - hypothetical protein VF1295 19 None None None 59711274 Common - N-acetylmannosamine kinase VF0667 147 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 59712834 Common - DNA topoisomerase IV subunit A VF2227 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 59712932 Common mutL DNA mismatch repair protein VF2325 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 59710694 Common - sensory transduction protein kinase VF0087 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 59711558 Common ruvA Holliday junction DNA helicase motor protein VF0951 212 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 59712780 Common - sulfate transporter VF2173 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 59711138 Common - cytosine deaminase VF0531 71 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 59711195 Common - molybdopterin biosynthesis MoeB protein VF0588 220 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 59711341 Common - DNA polymerase IV VF0734 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 59712453 Common fliL flagellar basal body-associated protein FliL VF1846 14 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 59711216 Common - outer membrane protein S VF0609 22 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 59711950 Nonpathogen - hypothetical protein VF1343 1 None None None 59710888 Common - hypothetical protein VF0281 33 COG2966 COG2966, Uncharacterized conserved protein Function unknown 59712652 Common - maltose transport system permease protein MalG VF2045 152 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 59711434 Common - methyl-accepting chemotaxis protein VF0827 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59713096 Common - glutathione reductase VF2489 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 59712377 Common - methenyltetrahydrofolate cyclohydrolase VF1770 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 59710710 Common - tRNA guanosine-2'-O-methyltransferase VF0103 200 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 59712820 Common - phosphoheptose isomerase VF2213 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 59710876 Common - thiamine transport ATP-binding protein ThiQ VF0269 249 COG3840 ThiQ, ABC-type thiamine transport system, ATPase component Coenzyme metabolism 59712925 Common - adenylosuccinate synthetase VF2318 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 59711355 Common - cell elongation specific D,D-transpeptidase VF0748 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 59712113 Common - iron-regulated protein FrpC VF1506 131 None None None 59712149 Common - acetyltransferase VF1542 26 COG0456 RimI, Acetyltransferases General function prediction only 59711647 Common - predicted inner membrane peptidase VF1040 189 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 59711079 Common - carbamoyl phosphate synthase small subunit VF0472 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 59712302 Common - acetyl-CoA carboxylase subunit beta VF1695 179 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 59711198 Common - DNA-binding transcriptional activator GcvA VF0591 188 COG0583 LysR, Transcriptional regulator Transcription 59712391 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase VF1784 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 59711527 Common - SSU ribosomal protein S4P VF0920 5 None None None 59712613 Nonpathogen - putative phage R protein VF2006 1 None None None 59713115 Common - L-seryl-tRNA selenium transferase family VF2508 65 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 59711731 Common - di-/tripeptide transporter VF1124 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 59711325 Common - 2-dehydropantoate 2-reductase VF0718 93 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 59713081 Common - general secretion pathway protein D VF2474 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 59712488 Common - negative regulator of flagellin synthesis FlgM VF1881 13 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 59710905 Common - acriflavin resistance plasma membrane protein VF0298 181 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 59712937 Common - ribosome-associated GTPase VF2330 163 COG1162 COG1162, Predicted GTPases General function prediction only 59712893 Common - tryptophanyl-tRNA synthetase VF2286 231 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59712783 Common - hypoxanthine-guanine phosphoribosyltransferase VF2176 143 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 59712028 Common - transporter VF1421 55 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 59712763 Common - gluconate permease VF2156 81 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 59711840 Common - hypothetical protein VF1233 2 None None None 59711652 Nonpathogen - hypothetical protein VF1045 2 None None None 59712560 Common - outer membrane protein OmpH VF1953 72 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 59712031 Common - MoxR protein VF1424 98 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 59711258 Common - amino-acid abc transporter binding protein VF0651 90 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 59713153 Common trkA potassium transporter peripheral membrane component VF2546 151 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 59712196 Common - hypothetical protein VF1589 9 COG4083 COG4083, Predicted membrane protein Function unknown 59712995 Common prmA ribosomal protein L11 methyltransferase VF2388 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 59710700 Common - adenosine deaminase VF0093 94 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 59710866 Common rpsM 30S ribosomal protein S13 VF0259 241 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 59711390 Common - thioredoxin VF0783 203 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 59712317 Common - outer membrane protein Slp precursor VF1710 30 COG3065 Slp, Starvation-inducible outer membrane lipoprotein Cell envelope biogenesis, outer membrane 59710614 Common - cystine transport system permease protein VF0007 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 59711110 Common - hypothetical protein VF0503 2 COG4317 COG4317, Uncharacterized protein conserved in bacteria Function unknown 59710620 Common - small heat shock protein VF0013 70 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 59711679 Common - transcriptional regulators, LysR family VF1072 103 COG0583 LysR, Transcriptional regulator Transcription 59712004 Common - sensor protein PhoQ VF1397 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59711046 Common - S-adenosylmethionine synthetase VF0439 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 59712623 Nonpathogen - hypothetical protein VF2016 1 None None None 59712461 Common - FlrC; two-component response regulator VF1854 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 59712388 Common - nitric oxide reductase VF1781 204 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 59711699 Common - toxin corregulated pilus biosynthesis protein I VF1092 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 59712142 Common - general L-amino acid transport ATP-binding protein AapP VF1535 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 59711832 Common - TonB protein VF1225 45 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 59711847 Common - nucleotide-binding protein VF1240 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 59710813 Common tpiA triosephosphate isomerase VF0206 221 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 59711991 Common - stringent starvation protein A VF1384 38 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 59712525 Common dapA dihydrodipicolinate synthase VF1918 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 59712569 Common rpsB 30S ribosomal protein S2 VF1962 221 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 59711729 Common - prolyl endopeptidase VF1122 127 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 59711722 Common murP N-acetylmuramic acid phosphotransfer permease VF1115 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 59712342 Common - thymidylate kinase VF1735 230 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 59711606 Common - ATP-dependent protease subunit VF0999 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 59711189 Common - exodeoxyribonuclease V beta chain VF0582 226 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 161986800 Common - prolyl-tRNA synthetase VF0682 244 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59712423 Common - cytochrome c-type biogenesis protein CcmI VF1816 51 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 59711312 Common - thiamine-monophosphate kinase VF0705 202 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 59711382 Common nirD nitrite reductase small subunit VF0775 46 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 59712174 Nonpathogen - hypothetical protein VF1567 2 None None None 59711466 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase VF0859 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 59710713 Common gmk guanylate kinase VF0106 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 59711937 Common - hypothetical protein VF1330 4 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 59711491 Common - ABC transporter ATP-binding protein VF0884 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 59712848 Common - arylsulfatase VF2241 28 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 59713176 Common - F0F1 ATP synthase subunit C VF2569 122 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 59711096 Common rpsO 30S ribosomal protein S15 VF0489 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 59711026 Common - membrane-bound lytic murein transglycosylase C precursor VF0419 121 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 59712589 Common - transcriptional regulator PhoU VF1982 193 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 59711738 Common - hypothetical protein VF1131 52 COG1432 COG1432, Uncharacterized conserved protein Function unknown 59712450 Common - flagellar protein FliO VF1843 32 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 59711059 Common - bacterial peptide chain release factor 2 (RF-2) VF0452 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 59710646 Common - virulence genes transcriptional regulator PhcA VF0039 83 COG0583 LysR, Transcriptional regulator Transcription 59710935 Common - hypothetical protein VF0328 8 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 59712099 Common - tRNA-(MS[2]IO[6]A)-hydroxylase VF1492 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 59711031 Common - coproporphyrinogen III oxidase VF0424 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 59711006 Common - YrbB protein VF0399 16 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 59711764 Common - cell wall degradation protein VF1157 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 59711824 Common rpmI 50S ribosomal protein L35 VF1217 127 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 59711215 Common - transcriptional regulator, LacI family VF0608 128 COG1609 PurR, Transcriptional regulators Transcription 59711865 Common - acyl-CoA hydrolase VF1258 136 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 59710944 Common metH B12-dependent methionine synthase VF0337 179 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 59712582 Common - alkyl hydroperoxide reductase C22 protein VF1975 226 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 59711720 Common - transcriptional regulator, RpiR family VF1113 133 COG1737 RpiR, Transcriptional regulators Transcription 59712249 Common - 2,4-dienoyl-CoA reductase [NADPH] VF1642 186 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 59713112 Common - permease VF2505 11 None None None 59712545 Common - hydroxyacylglutathione hydrolase VF1938 196 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 59711084 Common - hypothetical RNA binding protein VF0477 100 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 59711913 Common - nitrogen fixation protein FixS VF1306 17 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 59713044 Common - hypothetical protein VF2437 15 None None None 59712904 Common - pili assembly protein PilM VF2297 62 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 59711052 Common - methyltransferase VF0445 100 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 59711628 Common - methyltransferase VF1021 132 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 59711727 Common - acetyltransferase VF1120 98 COG3153 COG3153, Predicted acetyltransferase General function prediction only 59712246 Common - hypothetical protein VF1639 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 59710793 Common - dTDP-glucose 4,6-dehydratase VF0186 145 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 59711044 Common - endonuclease I VF0437 32 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 59710807 Common - acetyltransferase VF0200 12 None None None 59711162 Common - TagE-like gene VF0555 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 59711940 Common - transcriptional regulators, LysR family VF1333 147 COG0583 LysR, Transcriptional regulator Transcription 59711221 Common - myo-inositol-1(or 4)-monophosphatase VF0614 212 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 59712927 Common - protease activity modulator HflC VF2320 204 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 59710830 Common - peptidyl-prolyl cis-trans isomerase VF0223 117 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 59713128 Common - ATP-dependent DNA helicase rep VF2521 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 59712017 Common - putative efflux pump component MtrF VF1410 40 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 59712446 Common flhB flagellar biosynthesis protein FlhB VF1839 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 59711697 Common - transporter VF1090 92 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 59710997 Common - probable exported protein [imported] VF0390 26 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 59710659 Common - Sec-independent protein translocase protein TatD VF0052 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 59712696 Common - GTP-binding protein LepA VF2089 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 59711927 Common - NAD-dependent deacetylase VF1320 149 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 59710667 Common - 3-polyprenyl-4-hydroxybenzoate decarboxylase VF0060 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 59710903 Common - hypothetical protein VF0296 37 COG1309 AcrR, Transcriptional regulator Transcription 59712871 Common - long-chain-fatty-acid--CoA ligase VF2264 217 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 59712499 Common - putative sulfate transport protein CysZ VF1892 45 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 59712204 Common - oligopeptide-binding protein OppA VF1597 208 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 59712775 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase VF2168 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 59711230 Common - hypothetical protein VF0623 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 59712828 Common rpsI 30S ribosomal protein S9 VF2221 223 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 59710920 Common - hypothetical protein VF0313 5 None None None 59713065 Common - hypothetical protein VF2458 2 None None None 59710677 Common - ATP-dependent DNA helicase RecQ VF0070 230 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 59711593 Common - chitodextrinase precursor VF0986 71 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 59713106 Common - hypothetical protein VF2499 2 None None None 59712742 Common - glutamate-1-semialdehyde aminotransferase VF2135 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 59712304 Common - latent nuclear antigen VF1697 23 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 59711318 Common - 1-deoxy-D-xylulose-5-phosphate synthase VF0711 222 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 59712769 Common - multimodular transpeptidase-transglycosylase PBP 1B VF2162 201 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 59713117 Common - PTS system, mannitol (cryptic)-specific IIA component VF2510 36 COG3711 BglG, Transcriptional antiterminator Transcription 59711311 Common nusB transcription antitermination protein NusB VF0704 182 COG0781 NusB, Transcription termination factor Transcription 59712956 Common - preprotein translocase subunit SecB VF2349 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 59712960 Common aspA aspartate ammonia-lyase VF2353 225 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 59712537 Common - glutamine amidotransferase class-II VF1930 70 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 59712985 Common - sodium:solute symporter family protein VF2378 54 COG4147 DhlC, Predicted symporter General function prediction only 59711565 Common - TolQ protein VF0958 147 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 161986795 Common rseB periplasmic negative regulator of sigmaE VF2091 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 59712144 Common - hypothetical protein VF1537 27 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 59713061 Common - hypothetical protein VF2454 181 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 59712417 Common fadJ multifunctional fatty acid oxidation complex subunit alpha VF1810 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 59711337 Common - Na(+)-translocating NADH-quinone reductase subunit E VF0730 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 59712352 Common - hypothetical protein VF1745 55 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 59711582 Common - multidrug resistance ABC transporter ATP-binding and permease protein VF0975 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 59711463 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase VF0856 12 None None None 59712481 Common flgE flagellar hook protein FlgE VF1874 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 59711566 Common - TolR protein VF0959 136 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 59711146 Common - pyruvate carboxylase subunit B VF0539 211 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 59710689 Common - SAM-dependent methyltransferase VF0082 51 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 59710837 Common rpsL 30S ribosomal protein S12 VF0230 244 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 59712260 Common - hypothetical protein VF1653 53 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 59712300 Common - DedD protein VF1693 33 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 59712633 Common - putative phage tail protein VF2026 12 COG4379 COG4379, Mu-like prophage tail protein gpP General function prediction only 59710950 Common - hypothetical protein VF0343 7 None None None 59710681 Common - DNA polymerase I VF0074 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 59711890 Common - hypothetical protein VF1283 9 None None None 59712875 Common - transcriptional repressor protein MetJ VF2268 23 COG3060 MetJ, Transcriptional regulator of met regulon Transcription / Amino acid transport and metabolism 59711184 Common - hypothetical protein VF0577 17 COG3141 COG3141, Uncharacterized protein conserved in bacteria Function unknown 59712406 Common - lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase VF1799 74 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 59710730 Common - Ttk protein VF0123 43 None None None 59710974 Common - hypothetical protein VF0367 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 59712793 Common - pilus assembly protein PilB VF2186 213 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 59711410 Common rfaH transcriptional activator RfaH VF0803 99 COG0250 NusG, Transcription antiterminator Transcription 59711896 Common - ABC transporter ATPase component VF1289 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 59711136 Common - elongation factor G VF0529 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 59712212 Common - hypothetical protein VF1605 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 59710647 Common - transcriptional regulatory protein VF0040 86 COG0583 LysR, Transcriptional regulator Transcription 59713018 Common - DNA-directed RNA polymerase beta' chain VF2411 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 59710748 Common - UDP-bacillosamine synthetase VF0141 190 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 59711882 Common - paraquat-inducible protein B VF1275 56 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 59711392 Common proX glycine betaine transporter periplasmic subunit VF0785 67 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 59711855 Common - hypothetical protein VF1248 6 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 59711610 Common - hypothetical protein VF1003 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 59710724 Common - competence protein F VF0117 157 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 59711938 Nonpathogen - hypothetical protein VF1331 1 None None None 59712578 Common - acetoin utilization AcuB protein VF1971 150 COG0517 COG0517, FOG: CBS domain General function prediction only 59713144 Common - phosphoribosylaminoimidazole carboxylase catalytic subunit VF2537 231 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 59710787 Common - undecaprenyl-phosphate alpha-N-acetylglucosaminephosphotransferase VF0180 175 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 59712090 Common - murein hydrolase exporter VF1483 57 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 59712285 Common - NADH-dependent butanol dehydrogenase B VF1678 169 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 59713054 Common - integral membrane protein (rhomboid family) VF2447 38 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 59712758 Common - iron(III)-binding protein VF2151 107 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 59710909 Common alr alanine racemase VF0302 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 59711448 Common - dehydrogenase VF0841 40 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 59712394 Common - transcriptional regulator, AraC family VF1787 122 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 59710891 Common - dihydrofolate reductase VF0284 146 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 59711107 Common prfC peptide chain release factor 3 VF0500 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 59712086 Common - aquaporin Z VF1479 128 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 59711552 Common - hypothetical protein VF0945 19 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 59711427 Common - succinate dehydrogenase membrane anchor subunit VF0820 53 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 59711700 Common - glutamate-gated potassium channel VF1093 46 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 59711915 Common - transcriptional regulatory protein, Fnr VF1308 23 None None None 59711686 Common - hypothetical protein VF1079 5 None None None 59712682 Common eno phosphopyruvate hydratase VF2075 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 59712257 Common - phosphoglycerol transferase MdoB and related proteins, alkaline phosphatase superfamily VF1650 47 COG3083 COG3083, Predicted hydrolase of alkaline phosphatase superfamily General function prediction only 59711978 Common - permease VF1371 28 COG3817 COG3817, Predicted membrane protein Function unknown 59713099 Common - copper sensitivity protein ScsC VF2492 70 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 59710818 Common - ribonuclease activity regulator protein RraA VF0211 71 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 59712896 Common - DNA adenine methylase VF2289 97 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 59711808 Common nrdB ribonucleotide-diphosphate reductase subunit beta VF1201 153 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 59711420 Common - hypothetical protein VF0813 8 None None None 59713075 Common - general secretion pathway protein J VF2468 33 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 59712435 Nonpathogen - hypothetical protein VF1828 1 None None None 59712325 Common - MalT protein regulator VF1718 224 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 59712232 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase VF1625 208 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 59710919 Common - phosphoadenosine phosphosulfate reductase VF0312 155 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 59712411 Common - hypothetical membrane spanning protein VF1804 133 COG2860 COG2860, Predicted membrane protein Function unknown 59712440 Common - chemotaxis protein CheY VF1833 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 59710849 Common rpsC 30S ribosomal protein S3 VF0242 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 59711344 Common - guanine-hypoxanthine permease VF0737 139 COG2252 COG2252, Permeases General function prediction only 59711768 Common - periplasmic component of efflux system VF1161 123 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 59712801 Common - hypothetical protein VF2194 14 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 59712121 Common - Exonuclease KapD VF1514 15 COG5018 KapD, Inhibitor of the KinA pathway to sporulation, predicted exonuclease General function prediction only 59712500 Common - cysteine synthase VF1893 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 59711156 Common rpsP 30S ribosomal protein S16 VF0549 196 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 59712881 Common - primosome assembly protein PriA VF2274 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 59713147 Common - hypothetical protein VF2540 40 COG2922 Smg, Uncharacterized protein conserved in bacteria Function unknown 59712009 Common - molybdate-binding protein VF1402 62 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 59710842 Common - LSU ribosomal protein L3P VF0235 5 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 59711616 Common dinG ATP-dependent DNA helicase DinG VF1009 138 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 59712226 Common - sensor protein TorS VF1619 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59711224 Common - cysteine desulfurase VF0617 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 59711200 Common - methyltransferase VF0593 45 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 59712512 Common - nitrate reductase VF1905 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 59713181 Common gidB glucose-inhibited division protein B VF2574 200 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 59712648 Common - DNA integration/recombination/invertion protein VF2041 199 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 59711545 Common - hypothetical protein VF0938 4 None None None 59712891 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein VF2284 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 161986802 Common cyaA adenylate cyclase VF0067 25 COG3072 CyaA, Adenylate cyclase Nucleotide transport and metabolism 59711578 Common - GTP-binding protein HflX VF0971 216 COG2262 HflX, GTPases General function prediction only 59712022 Common - multidrug efflux protein VF1415 177 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 59713031 Common - pantothenate kinase VF2424 72 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 59711209 Common - hypothetical protein VF0602 4 None None None 59712557 Common - UDP-N-acetylglucosamine acyltransferase VF1950 162 COG1043 LpxA, Acyl- acyl carrier protein 59711419 Common - flavodoxin FldA VF0812 73 COG0716 FldA, Flavodoxins Energy production and conversion 59711664 Common - lysine exporter protein VF1057 110 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 59711908 Common - hypothetical protein VF1301 8 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 59712857 Common rpsU 30S ribosomal protein S21 VF2250 106 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 59712251 Common ansA cytoplasmic asparaginase I VF1644 136 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 59712669 Common - hypothetical protein VF2062 60 COG2391 COG2391, Predicted transporter component General function prediction only 59711458 Common - hypothetical protein VF0851 146 COG4261 COG4261, Predicted acyltransferase General function prediction only 59712386 Common - tellurite resistance protein TehB VF1779 17 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 59713109 Common - transcriptional regulator VF2502 11 None None None 59710774 Common - Glucose-1-phosphate thymidylyltransferase VF0167 234 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 59712735 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase VF2128 110 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 59710912 Common - possible inhibitor of MCP methylation VF0305 26 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 59711904 Common - hypothetical protein VF1297 21 COG3287 COG3287, Uncharacterized conserved protein Function unknown 59711265 Common - ribosomal protein S6 modification protein VF0658 160 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 59711399 Common - heat shock protein 90 VF0792 148 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 59710692 Common - universal stress protein UspB VF0085 12 None None None 59712276 Common - naphthoate synthase VF1669 168 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 59710656 Common tatA twin argininte translocase protein A VF0049 56 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 59712038 Nonpathogen - hypothetical protein VF1431 2 None None None 59713021 Common - DNA-directed RNA polymerase beta chain VF2414 216 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 59712062 Common - mechanosensitive ion channel VF1455 207 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 59711931 Common - hypothetical protein VF1324 83 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 59711436 Common - high-affinity zinc uptake system ATP-binding protein ZnuC VF0829 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 59712072 Common - superfamily I DNA and RNA helicases VF1465 221 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 59712918 Common rpsR 30S ribosomal protein S18 VF2311 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 59712229 Common helD DNA helicase IV VF1622 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 59712335 Common - hypothetical protein VF1728 4 None None None 59711408 Common - COME operon protein 1 VF0801 86 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 59710938 Common - peptide methionine sulfoxide reductase VF0331 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 59711974 Common - two-component response regulator VF1367 120 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 59710706 Common - GTP-binding protein TypA/BipA VF0099 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 59713132 Common - hypothetical protein VF2525 42 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 59713170 Common atpC F0F1 ATP synthase subunit epsilon VF2563 173 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 59712747 Common - chitooligosaccharide transport system permease protein VF2140 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 59711481 Common secF preprotein translocase subunit SecF VF0874 206 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 59712305 Common - aspartate-semialdehyde dehydrogenase VF1698 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 59712310 Common - protein YcgL VF1703 33 COG3100 COG3100, Uncharacterized protein conserved in bacteria Function unknown 59711287 Common - oligopeptide transport system permease protein OppB VF0680 211 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 59712183 Common - glycoprotein/polysaccharide metabolism VF1576 27 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 59710952 Common - lipopolysaccharide N-acetylglucosaminyltransferase VF0345 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 59712363 Common - hypothetical protein VF1756 63 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 59712158 Common - NrfD protein VF1551 25 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 59713091 Common dapF diaminopimelate epimerase VF2484 201 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 59712603 Common - GrpE protein VF1996 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 59711949 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit VF1342 33 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 59711631 Common - acyl-CoA hydrolase VF1024 133 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 59711500 Common - hypothetical protein VF0893 2 None None None 59712002 Common - hypothetical protein VF1395 9 COG3212 COG3212, Predicted membrane protein Function unknown 59711510 Common - alanine dehydrogenase VF0903 165 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 59711761 Common - hypothetical protein VF1154 2 None None None 59713162 Common - ATPase related to magnesium chelatase subunit ChlI VF2555 204 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 59711417 Common fur ferric uptake regulator VF0810 197 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 59711783 Common - L-serine dehydratase VF1176 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 59712294 Common - DNA polymerase III subunits gamma and tau VF1687 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 59712990 Common - acetyl-coenzyme A synthetase VF2383 201 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 59711048 Common - D-erythrose 4-phosphate dehydrogenase VF0441 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 59712756 Common - ABC transporter ATP-binding protein VF2149 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 59710984 Common - hypothetical protein VF0377 56 COG3164 COG3164, Predicted membrane protein Function unknown 59712842 Common - bifunctional glutamine-synthetase adenylyltransferase/deadenyltransferase VF2235 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 59711011 Common - translation initiation inhibitor VF0404 186 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 59710642 Common thiG thiazole synthase VF0035 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 59713124 Common - dipeptide transport system permease protein DppB VF2517 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 59711637 Common - anthranilate phosphoribosyltransferase VF1030 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 59713083 Common - heat shock protein 15 VF2476 87 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 59712621 Common - terminase, ATPase subunit VF2014 23 COG5484 COG5484, Uncharacterized conserved protein Function unknown 59710635 Common hemG protoporphyrinogen oxidase VF0028 32 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 59711504 Common - hypothetical protein VF0897 4 None None None 59711845 Common - succinylglutamate desuccinylase VF1238 24 COG2988 COG2988, Succinylglutamate desuccinylase Amino acid transport and metabolism 59711922 Common potA putrescine/spermidine ABC transporter ATPase protein VF1315 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 59710898 Common - hypothetical protein VF0291 24 None None None 59712371 Common infA translation initiation factor IF-1 VF1764 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 59711112 Common deoA thymidine phosphorylase VF0505 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 59710858 Common rpsH 30S ribosomal protein S8 VF0251 222 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 59711672 Common - integral membrane protein with TrkA domains VF1065 57 COG2985 COG2985, Predicted permease General function prediction only 59711756 Common - hypothetical protein VF1149 105 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 59712551 Common - cell cycle protein MesJ VF1944 80 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 59711650 Common - hypothetical protein VF1043 7 None None None 59712760 Common - nitrogen regulatory protein GlnK VF2153 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 59712168 Common - sensory box/GGDEF family protein VF1561 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 59711960 Common - virulence gene repressor RsaL VF1353 41 COG2944 COG2944, Predicted transcriptional regulator Transcription 59711798 Common - hypothetical protein VF1191 49 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 59712349 Common - 3-oxoacyl-(acyl carrier protein) synthase III VF1742 225 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 59711256 Common - transcriptional regulators, LysR family VF0649 176 COG0583 LysR, Transcriptional regulator Transcription 59711987 Common - penicillin-binding protein VF1380 118 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 59711455 Common - DNA gyrase subunit B VF0848 24 COG4648 COG4648, Predicted membrane protein Function unknown 59712458 Common fliG flagellar motor switch protein G VF1851 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 59712140 Common - general L-amino acid transport system permease protein AapQ VF1533 173 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 59710776 Common - hypothetical protein VF0169 15 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 59711747 Common - methyltransferase VF1140 57 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 59711074 Common ileS isoleucyl-tRNA synthetase VF0467 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59712509 Common - hypothetical protein VF1902 2 None None None 59710868 Common rpsD 30S ribosomal protein S4 VF0261 218 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 59712567 Common pyrH uridylate kinase VF1960 233 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 59711353 Common - lipoprotein VF0746 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 59712954 Common - serine acetyltransferase VF2347 187 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 59711959 Common - hypothetical protein VF1352 22 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 59712997 Common - tRNA-dihydrouridine synthase VF2390 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 59712625 Nonpathogen - hypothetical protein VF2018 1 None None None 59711604 Common - phospho-specific protein-protein interaction motif FHA VF0997 29 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 59712593 Common - phosphate-binding protein VF1986 114 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 59712463 Common - FlrA; sigma-54-dependent transcriptional activator VF1856 169 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 59710886 Common rpmA 50S ribosomal protein L27 VF0279 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 59711272 Common - N-acetylglucosamine-6-phosphate deacetylase VF0665 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 59711103 Common - acetyltransferase VF0496 93 COG3153 COG3153, Predicted acetyltransferase General function prediction only 59712029 Common - hypothetical protein VF1422 58 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 59712934 Common - ATP/GTP hydrolase VF2327 208 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 59711022 Common - hypothetical membrane spanning protein VF0415 106 COG0795 COG0795, Predicted permeases General function prediction only 59712832 Common - endopeptidase DegP VF2225 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 59710851 Common rpmC 50S ribosomal protein L29 VF0244 29 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 59712650 Common - maltose/maltodextrin-binding protein VF2043 73 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 59713015 Common - regulatory protein CsgD VF2408 159 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 59712976 Common - carbonic anhydrase VF2369 177 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 59710874 Common tbpA thiamin transporter substrate binding subunit VF0267 70 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 59712516 Common - nitrate/nitrite response regulator protein NarP VF1909 222 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 59712796 Common - dephospho-CoA kinase VF2189 203 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 59711677 Common - CDP-4-dehydro-6-deoxy-D-glucose 3-dehydratase VF1070 28 COG5361 COG5361, Uncharacterized conserved protein Function unknown 59712616 Nonpathogen - hypothetical protein VF2009 1 None None None 59712965 Common - transporter, MFS superfamily VF2358 30 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 59712987 Common - putative 3-phenylpropionic acid transporter VF2380 72 None None None 59712115 Common - anaerobic C4-dicarboxylate transporter VF1508 24 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 59712900 Common - pili secretion protein PilQ VF2293 137 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 59712010 Common - molybdenum transport system permease protein ModB VF1403 172 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 59712147 Common - suppressor/enhancer of lin-12 VF1540 98 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 59711801 Common - hydroxyacylglutathione hydrolase VF1194 218 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 59711327 Common - AmpG protein VF0720 109 None None None 59712055 Common - ribokinase VF1448 202 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 59711304 Common - hypothetical protein VF0697 2 None None None 59711659 Common - transporter, divalent anion:sodium symporter family VF1052 122 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 59712789 Common pdhR transcriptional regulator PdhR VF2182 142 COG2186 FadR, Transcriptional regulators Transcription 59711719 Common - nonspecific acid phosphatase precursor VF1112 25 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 59712969 Common - GGDEF family protein VF2362 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 59713033 Common - UDP-N-acetylenolpyruvoylglucosamine reductase VF2426 203 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 59712348 Common - acyl carrier protein S-malonyltransferase VF1741 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 59711781 Common - hypothetical protein VF1174 3 None None None 59712935 Common - iron-sulfur cluster-binding protein VF2328 138 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 59713026 Common rplK 50S ribosomal protein L11 VF2419 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 59711778 Common - tyrosine-specific transport protein VF1171 33 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 59711303 Common - accessory colonization factor AcfD-like protein VF0696 3 None None None 161986792 Common - DNA-binding transcriptional repressor FabR VF2438 60 COG1309 AcrR, Transcriptional regulator Transcription 59712773 Common - poly(A) polymerase VF2166 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 59711860 Common - cystathionine beta-lyase VF1253 235 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 59711513 Common lolA outer-membrane lipoprotein carrier protein VF0906 65 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 161986803 Common fadA 3-ketoacyl-CoA thiolase VF0024 183 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 59712327 Common - DNA-binding transcriptional repressor VF1720 131 COG1609 PurR, Transcriptional regulators Transcription 59711285 Common - oligopeptide transport ATP-binding protein OppD VF0678 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 59712873 Common metL bifunctional aspartate kinase II/homoserine dehydrogenase II VF2266 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 59710973 Common - MshA, mannose-sensitive haemaglutinin VF0366 10 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 59711160 Common - phospho-2-dehydro-3-deoxyheptonate aldolase VF0553 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 59712598 Common - ferredoxin VF1991 107 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 59711595 Common - hypothetical protein VF0988 24 COG3137 COG3137, Putative salt-induced outer membrane protein Cell envelope biogenesis, outer membrane 59712019 Common - hypothetical protein VF1412 7 None None None 59711328 Common - peptidyl-prolyl cis-trans isomerase VF0721 196 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 59712686 Common - flagellin VF2079 122 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 59712631 Common - hypothetical protein VF2024 2 None None None 59712444 Common flhA flagellar biosynthesis protein A VF1837 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 59711892 Common - dihydroorotate dehydrogenase 2 VF1285 230 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 59710937 Common - hypothetical protein VF0330 14 None None None 59711726 Common - hypothetical protein VF1119 27 COG0730 COG0730, Predicted permeases General function prediction only 59712929 Common - putative GTPase HflX VF2322 230 COG2262 HflX, GTPases General function prediction only 59712963 Common dipZ thiol:disulfide interchange protein precursor VF2356 172 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 59712838 Common - phosphohydrolase (MutT/nudix family protein) VF2231 25 COG3151 COG3151, Uncharacterized protein conserved in bacteria Function unknown 59712255 Common - nucleoid-associated protein NdpA VF1648 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 59710821 Common - phosphoribulokinase VF0214 51 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 59712518 Common - hypothetical protein VF1911 9 COG4519 COG4519, Uncharacterized protein conserved in bacteria Function unknown 59711438 Common - cell wall endopeptidase, family M23/M37 VF0831 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 59711681 Common - transcriptional regulator, AraC family VF1074 134 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 59712206 Common - thymidine kinase VF1599 92 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 59712365 Common - integration host factor beta-subunit VF1758 202 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 59710669 Common fre FMN reductase VF0062 97 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 59712826 Common - ubiquinol-cytochrome c reductase iron-sulfur subunit VF2219 28 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 59713067 Common - ATP-dependent DNA helicase RecG VF2460 228 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 59712867 Common - hypothetical protein VF2260 1 None None None 59712704 Common - aminomethyltransferase homolog VF2097 97 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 59712744 Common - 16S rRNA m(2)G 1207 methyltransferase VF2137 97 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 59712767 Nonpathogen - hypothetical protein VF2160 1 None None None 59710686 Common - putative coproporphyrinogen III oxidase VF0079 11 None None None 59713108 Common - hypothetical protein VF2501 2 None None None 59711042 Common - glutathione synthetase VF0435 127 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 59711773 Common - hypothetical protein VF1166 13 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 59712548 Common - hypothetical protein VF1941 33 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 59711993 Common - acetyltransferase, GNAT family VF1386 6 COG3375 COG3375, Uncharacterized conserved protein Function unknown 59711540 Common - electron transport complex protein RnfC VF0933 103 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 59712265 Common - short chain dehydrogenase VF1658 228 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 59712477 Common flgI flagellar basal body P-ring protein VF1870 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 59712108 Common - DsrC protein homolog VF1501 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 59711003 Common - toluene tolerance protein TTG2C VF0396 93 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 59712412 Common - chorismate synthase VF1805 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 59712580 Common - malate synthase VF1973 85 COG2225 AceB, Malate synthase Energy production and conversion 59710769 Common - putative polysaccharide export protein YccZ precursor VF0162 127 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 59710715 Common - hypothetical protein VF0108 1 None None None 59712379 Common - hypothetical protein VF1772 69 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 59711762 Common - proton glutamate symport protein VF1155 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 59711602 Common - hypothetical protein VF0995 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 59711516 Common - thioredoxin 2 VF0909 228 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 59710745 Common - 3-deoxy-D-manno-octulosonic-acid transferase VF0138 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 59712331 Common dcuC C4-dicarboxylate transporter DcuC VF1724 24 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 59712587 Common - hypothetical protein VF1980 2 None None None 59711388 Common - copper-exporting ATPase VF0781 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 59711094 Common rbfA ribosome-binding factor A VF0487 166 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 59711343 Common - aminoacyl-histidine dipeptidase VF0736 60 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 59710963 Common - hypothetical protein VF0356 9 None None None 59711034 Common - hypothetical protein VF0427 75 COG1872 COG1872, Uncharacterized conserved protein Function unknown 59713042 Common - vitamin B12 receptor VF2435 129 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 59711380 Common - uroporphyrin-III C-methyltransferase VF0773 204 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 59710661 Common - guanosine pentaphosphate phosphohydrolase VF0054 181 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 59710755 Common - flagellin modification protein A VF0148 169 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 59712919 Common rpsF 30S ribosomal protein S6 VF2312 194 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 59710942 Common - hypothetical protein VF0335 4 None None None 59712217 Common - phosphate-binding protein VF1610 192 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 59711364 Common - hypothetical protein VF0757 201 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 59710644 Common - hypothetical protein VF0037 56 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 59712214 Common folE GTP cyclohydrolase I VF1607 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 59711874 Common - hypothetical protein VF1267 38 None None None 59710690 Common - universal stress protein A VF0083 37 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 59711359 Common - rare lipoprotein B precursor VF0752 33 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 59712053 Common rbsC ribose ABC transporter permease protein VF1446 118 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 59712722 Common - autonomous glycyl radical cofactor GrcA VF2115 52 COG3445 COG3445, Acid-induced glycyl radical enzyme General function prediction only 59711645 Common - ribosomal large subunit pseudouridine synthase B VF1038 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 59711449 Common - putative O-methyltransferase VF0842 25 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 59712814 Common - cell division protein FtsI VF2207 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 59712729 Common - aerobic respiration control sensor protein ArcB VF2122 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 59711554 Common - methyltransferase VF0947 53 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 59711688 Common - transcriptional regulator, TetR family VF1081 83 COG1309 AcrR, Transcriptional regulator Transcription 59712274 Common - O-succinylbenzoate synthase VF1667 74 COG1441 MenC, O-succinylbenzoate synthase Coenzyme metabolism 59713004 Common - DNA-binding protein HU VF2397 214 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 59712667 Common - DNA-binding transcriptional activator VF2060 40 COG3710 CadC, DNA-binding winged-HTH domains Transcription 59711348 Common proA gamma-glutamyl phosphate reductase VF0741 189 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 59711475 Common - hypothetical protein VF0868 6 None None None 59712550 Common - cytochrome c-554(548) VF1943 51 COG2863 COG2863, Cytochrome c553 Energy production and conversion 59711109 Common - Nucleoside permease NupC VF0502 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 59711442 Common - hypothetical protein VF0835 3 None None None 59711176 Common - hypothetical protein VF0569 2 None None None 59710785 Common - 3-deoxy-manno-octulosonate cytidylyltransferase VF0178 141 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 59712425 Common - thiol:disulfide interchange protein TlpA VF1818 125 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 59712430 Common - heme exporter protein B VF1823 83 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 59711028 Common - hypothetical protein VF0421 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 59712088 Common - penicillin binding protein transpeptidase VF1481 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 59711708 Common - hypothetical protein VF1101 26 None None None 59712438 Common - chemotaxis protein CheA VF1831 149 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 59711753 Common - chitodextrinase precursor VF1146 5 None None None 59713145 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit VF2538 194 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 59713077 Common - general secretion pathway protein H VF2470 9 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 59711816 Common - membrane metalloprotease VF1209 29 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 59712106 Common - hypothetical protein VF1499 1 None None None 59712358 Common - AsmA VF1751 60 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 59712124 Common - heat shock protein 70 VF1517 47 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 59712800 Common secA preprotein translocase subunit SecA VF2193 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 59712894 Common - phosphoglycolate phosphatase VF2287 201 COG0546 Gph, Predicted phosphatases General function prediction only 59710941 Common - hypothetical protein VF0334 4 None None None 59712749 Common - oligosaccharide transport ATP-binding protein VF2142 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 59711635 Common - tryptophan synthase subunit beta VF1028 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 59712566 Common frr ribosome recycling factor VF1959 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 59712244 Common - hypothetical protein VF1637 5 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 59711897 Common - hypothetical protein VF1290 5 None None None 59712684 Common - hypothetical protein VF2077 58 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 59712419 Common - long-chain fatty acid transport protein precursor VF1812 73 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 59711154 Common - CcsA-related protein VF0547 62 COG4137 COG4137, ABC-type uncharacterized transport system, permease component General function prediction only 59711574 Common - hypothetical protein VF0967 13 None None None 59712586 Common - transcriptional regulators, LysR family VF1979 134 COG0583 LysR, Transcriptional regulator Transcription 59712262 Common - hypothetical protein VF1655 4 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 59711339 Common - iron-sulfur cluster assembly/repair protein ApbE VF0732 135 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 59712809 Common - cell division protein FtsW VF2202 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 59710738 Common - phosphoglycerol transferase MdoB and related proteins, alkaline phosphatase superfamily VF0131 47 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 59711412 Common - glutathione-regulated potassium-efflux system protein KefC VF0805 111 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 59711314 Common - LuxP protein precursor VF0707 15 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 59711531 Common - transport protein VF0924 29 COG2056 COG2056, Predicted permease General function prediction only 59713063 Common - multiple antibiotic resistance protein MarC VF2456 154 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 59711560 Common - cytochrome d ubiquinol oxidase subunit I VF0953 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 59711585 Common - quinone oxidoreductase VF0978 169 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 59712490 Common - hypothetical protein VF1883 15 COG3018 COG3018, Uncharacterized protein conserved in bacteria Function unknown 59710687 Common - coproporphyrinogen III oxidase VF0080 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 59711528 Common - superoxide dismutase VF0921 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 59712380 Common - hypothetical protein VF1773 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 59711461 Common - hypothetical protein VF0854 24 None None None 59712483 Common flgC flagellar basal body rod protein FlgC VF1876 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 59711086 Common - cell division protein FtsH VF0479 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 59712350 Common - fatty acid/phospholipid synthesis protein VF1743 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 59711057 Common - ssDNA exonuclease RecJ VF0450 195 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 59711148 Common - hypothetical protein VF0541 76 COG1238 COG1238, Predicted membrane protein Function unknown 59712296 Common - Hnr protein VF1689 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 59712535 Common - phosphoribosylaminoimidazole synthetase VF1928 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 59712674 Common - RNA polymerase sigma factor RpoS VF2067 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 59711321 Common - flagellar motor protein PomA VF0714 98 COG1291 MotA, Flagellar motor component Cell motility and secretion 59710836 Common - intracellular sulfur oxidation protein dsrF VF0229 36 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 59712287 Common - transporter, drug/metabolite exporter family VF1680 111 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 59712886 Common - OsmC-like protein VF2279 85 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 59712807 Common murC UDP-N-acetylmuramate--L-alanine ligase VF2200 207 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 59711295 Common - oligopeptide transport system permease protein OppB VF0688 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 59711884 Common - transporter VF1277 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 59710995 Common - ABC transporter ATP-binding protein VF0388 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 59711100 Common - putative protease YhbU precursor VF0493 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 59712981 Common - two-component response regulator VF2374 159 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 59711822 Common - threonyl-tRNA synthetase VF1215 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 59712877 Common - hypothetical protein VF2270 14 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 59710795 Common - hypothetical protein VF0188 28 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 59712920 Common - 23S rRNA (guanosine-2'-O-)-methyltransferase VF2313 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 59712049 Common - hypothetical protein VF1442 12 COG0011 COG0011, Uncharacterized conserved protein Function unknown 59710732 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase VF0125 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism