Legionella pneumophila str. Paris, complete genome NC_006368 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 54296389 Common rpsD 30S ribosomal protein S4 lpp0418 228 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 54298503 Pathogen - hypothetical protein lpp2567 1 None None None 54296046 Common - hypothetical protein lpp0063 2 None None None 54296289 Common - hypothetical protein lpp0318 106 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 54297436 Common pilD Type 4 prepilin-like proteins leader peptide processing enzyme lpp1481 142 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 54297181 Common flgD flagellar basal body rod modification protein lpp1226 90 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 54296421 Common uvrA excinuclease ABC subunit A lpp0451 244 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 54298090 Pathogen - hypothetical protein lpp2147 1 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 54296919 Common mutY hypothetical protein lpp0960 234 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 54298879 Common - hypothetical protein lpp2946 165 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 54297837 Common - hypothetical protein lpp1889 32 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 54296356 Common rplJ 50S ribosomal protein L10 lpp0385 206 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 54297850 Common - hypothetical protein lpp1902 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 54297903 Common - major outer membrane protein lpp1958 3 None None None 54296170 Pathogen - hypothetical protein lpp0193 4 None None None 54298984 Common parC DNA topoisomerase IV subunit A lpp3051 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 54298004 Common - hypothetical protein lpp2061 102 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 54296839 Common clpA ATP-dependent Clp protease ATP-binding subunit ClpA lpp0880 225 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 54295989 Common speA arginine decarboxylase lpp0006 124 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 54298473 Common hypD Hydrogenase expression/formation protein HypD lpp2537 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 54296340 Common - hypothetical protein lpp0369 43 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 54297930 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase lpp1985 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 54297580 Pathogen - hypothetical protein lpp1631 1 None None None 54297774 Common - hypothetical protein lpp1825 143 None None None 54298051 Pathogen - hypothetical protein lpp2108 1 None None None 54296751 Common - hypothetical protein lpp0790 34 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 54297141 Pathogen - hypothetical protein lpp1186 1 None None None 54296765 Common - hypothetical protein lpp0804 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 54298048 Common - hypothetical protein lpp2105 93 COG2378 COG2378, Predicted transcriptional regulator Transcription 54298307 Pathogen - hypothetical protein lpp2365 1 None None None 54298885 Common - hypothetical protein lpp2952 46 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 54296796 Pathogen - hypothetical protein lpp0836 1 None None None 54296268 Common cyoD Cytochrome o ubiquinol oxidase subunit IV lpp0297 56 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 54297171 Pathogen - hypothetical protein lpp1216 1 None None None 54298262 Pathogen - hypothetical protein lpp2320 1 None None None 54298251 Common dnaG DNA primase lpp2309 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 54298184 Common - hypothetical protein lpp2241 154 COG0546 Gph, Predicted phosphatases General function prediction only 54298353 Pathogen - hypothetical protein lpp2413 1 None None None 54297256 Common - hypothetical protein lpp1301 47 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 54297602 Common - hypothetical protein lpp1653 161 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 54296200 Common - hypothetical protein lpp0226 51 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 54298464 Common - hypothetical protein lpp2528 6 COG0500 SmtA, SAM-dependent methyltransferases Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54297073 Pathogen - hypothetical protein lpp1118 1 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 54298420 Pathogen - hypothetical protein lpp2484 1 None None None 54296439 Common - hypothetical protein lpp0470 102 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 54297643 Common - hypothetical protein lpp1694 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 54296937 Common murE hypothetical protein lpp0978 215 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 54298013 Pathogen - hypothetical protein lpp2070 1 None None None 54297968 Common - hypothetical protein lpp2023 22 COG3407 MVD1, Mevalonate pyrophosphate decarboxylase Lipid metabolism 54298136 Common - hypothetical protein lpp2193 28 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54298665 Common dotC defect in organelle trafficking lipoprotein DotC lpp2729 10 None None None 54297624 Common - hypothetical protein lpp1675 2 COG3245 CycB, Cytochrome c5 Energy production and conversion 54296692 Common - hypothetical protein lpp0723 28 None None None 54297827 Common - hypothetical protein lpp1879 61 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 54298583 Common fmt hypothetical protein lpp2647 220 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 54298290 Common - hypothetical protein lpp2348 21 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 54296599 Common gor glutathione reductase lpp0630 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 54296070 Common - hypothetical protein lpp0088 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 54297123 Pathogen - hypothetical protein lpp1168 1 None None None 54298063 Common - hypothetical protein lpp2120 5 None None None 54298632 Pathogen - hypothetical protein lpp2696 1 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 54297410 Pathogen - hypothetical protein lpp1455 1 None None None 54296846 Common - hypothetical protein lpp0887 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 54298639 Common rpmA 50S ribosomal protein L27 lpp2703 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 54296771 Common lipA lipoyl synthase lpp0810 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 54296703 Common - hypothetical protein lpp0734 154 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 54297442 Common prpC 2-methylcitrate synthase lpp1487 194 COG0372 GltA, Citrate synthase Energy production and conversion 54297986 Common dbpA ATP-dependent RNA helicase DbpA lpp2042 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 54296000 Pathogen - hypothetical protein lpp0017 1 COG1289 COG1289, Predicted membrane protein Function unknown 54296282 Common - hypothetical protein lpp0311 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 54295990 Common - hypothetical protein lpp0007 199 COG0388 COG0388, Predicted amidohydrolase General function prediction only 54296651 Common - hypothetical protein lpp0682 40 COG3419 PilY1, Tfp pilus assembly protein, tip-associated adhesin PilY1 Cell motility and secretion / Intracellular trafficking and secretion 54298269 Common - hypothetical protein lpp2327 3 None None None 54298852 Common - hypothetical protein lpp2919 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 54298463 Pathogen - hypothetical protein lpp2527 1 None None None 54297038 Common - hypothetical protein lpp1080 71 COG3727 Vsr, DNA G:T-mismatch repair endonuclease DNA replication, recombination, and repair 54296138 Common - hypothetical protein lpp0160 3 None None None 54297109 Pathogen - hypothetical protein lpp1154 1 None None None 54297847 Pathogen - hypothetical protein lpp1899 1 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 54296934 Common - hypothetical protein lpp0975 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 54296538 Common - hypothetical protein lpp0569 155 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 54296811 Common - hypothetical protein lpp0851 3 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 54297555 Common - hypothetical protein lpp1605 13 COG5485 COG5485, Predicted ester cyclase General function prediction only 54297099 Common - hypothetical protein lpp1144 43 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54297514 Pathogen - hypothetical protein lpp1561 1 None None None 54297584 Common - hypothetical protein lpp1635 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 54296428 Common - hypothetical protein lpp0459 148 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 54297859 Pathogen - hypothetical protein lpp1914 1 None None None 54296362 Common fusA elongation factor G lpp0391 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 54297522 Common - hypothetical protein lpp1570 27 None None None 54296142 Common prpA hypothetical protein lpp0165 14 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 54298865 Common asg hypothetical protein lpp2932 135 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 54296747 Common - hypothetical protein lpp0786 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 54296327 Pathogen - hypothetical protein lpp0356 1 None None None 54297636 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein lpp1687 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 54296254 Common - hypothetical protein lpp0281 204 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 54296373 Common rpmC 50S ribosomal protein L29 lpp0402 131 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 54297804 Common - hypothetical protein lpp1855 2 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 54297766 Common - hypothetical protein lpp1817 163 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 54296631 Common - hypothetical protein lpp0662 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 54297301 Common rpmF 50S ribosomal protein L32 lpp1346 68 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 54297221 Common truA tRNA pseudouridine synthase A lpp1266 234 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 54297733 Common pyrD dihydroorotate dehydrogenase 2 lpp1784 225 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 54296400 Pathogen - hypothetical protein lpp0429 1 None None None 54297864 Common - hypothetical protein lpp1919 61 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 54296451 Pathogen - hypothetical protein lpp0482 1 None None None 54298660 Common - hypothetical protein lpp2724 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 54298679 Pathogen icmX Intracellular multiplication protein IcmX lpp2743 2 None None None 54296788 Common - hypothetical protein lpp0827 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 54298022 Common - hypothetical protein lpp2079 98 COG1733 COG1733, Predicted transcriptional regulators Transcription 54296209 Common - hypothetical protein lpp0235 182 COG0583 LysR, Transcriptional regulator Transcription 54296787 Common rmlA glucose-1-phosphate thymidylyltransferase lpp0826 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 54297243 Common - hypothetical protein lpp1288 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 54297661 Common - hypothetical protein lpp1712 213 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 54297545 Pathogen - hypothetical protein lpp1595 1 None None None 54297831 Common gst glutathione S-transferase lpp1883 91 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 54297008 Common - hypothetical protein lpp1049 4 None None None 54296063 Pathogen - hypothetical protein lpp0081 1 None None None 54297493 Common - hypothetical protein lpp1538 91 COG3038 CybB, Cytochrome B561 Energy production and conversion 54297695 Common fliA flagellar biosynthesis sigma factor lpp1746 215 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 54298540 Pathogen - hypothetical protein lpp2604 1 None None None 54298768 Common nuoE NADH dehydrogenase I chain E lpp2832 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 54297276 Common - hypothetical protein lpp1321 54 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 54296095 Common lpxD hypothetical protein lpp0114 163 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 54298720 Common tgt hypothetical protein lpp2784 227 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 54297956 Common folB hypothetical protein lpp2011 108 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 54296382 Common rpsE 30S ribosomal protein S5 lpp0411 228 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 54297213 Common gloB hydroxyacylglutathione hydrolase (glyoxalase II) lpp1258 134 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 54296273 Common - hypothetical protein lpp0302 96 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 54297504 Common rpsR 30S ribosomal protein S18 lpp1549 213 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 54298924 Common - hypothetical protein lpp2991 159 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 54297541 Pathogen - hypothetical protein lpp1591 1 None None None 54298532 Common - hypothetical protein lpp2596 177 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 54296503 Common - hypothetical protein lpp0534 67 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 54296676 Common - hypothetical protein lpp0707 143 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 54298907 Pathogen tatB Putative TatB protein (twin arginine translocation) lpp2974 1 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 54297891 Common - hypothetical protein lpp1946 197 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 54297401 Common - hypothetical protein lpp1446 122 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 54296103 Pathogen - hypothetical protein lpp0122 1 None None None 54298611 Common - hypothetical protein lpp2675 3 COG4870 COG4870, Cysteine protease Posttranslational modification, protein turnover, chaperones 54298312 Common helA HelA protein lpp2371 177 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 54298592 Pathogen - hypothetical protein lpp2656 1 None None None 54296018 Common - hypothetical protein lpp0035 12 None None None 54296590 Common - hypothetical protein lpp0621 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54297033 Common - hypothetical protein lpp1075 2 None None None 54296713 Common - hypothetical protein lpp0744 127 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 54296347 Common surA hypothetical protein lpp0376 165 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 54296051 Pathogen - hypothetical protein lpp0069 1 None None None 54297146 Common - hypothetical protein lpp1191 4 None None None 54297029 Common - hypothetical protein lpp1071 21 None None None 54297356 Common scpB hypothetical protein lpp1401 153 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 54298486 Common algC phosphomannomutase lpp2550 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 54296556 Pathogen - hypothetical protein lpp0587 2 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 54297793 Common - hypothetical protein lpp1844 35 COG1626 TreA, Neutral trehalase Carbohydrate transport and metabolism 54297568 Common - hypothetical protein lpp1619 29 COG5572 COG5572, Predicted integral membrane protein Function unknown 54298539 Common - hypothetical protein lpp2603 60 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 54298226 Common prfA peptide chain release factor 1 lpp2284 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 54297121 Common - acetylornithine deacetylase lpp1166 207 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 54297870 Common - hypothetical protein lpp1925 82 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 54298214 Common - hypothetical protein lpp2272 5 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 54297248 Pathogen - hypothetical protein lpp1293 1 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 54296235 Common - hypothetical protein lpp0261 34 COG3752 COG3752, Predicted membrane protein Function unknown 54296261 Pathogen - hypothetical protein lpp0288 1 None None None 54298822 Common - hypothetical protein lpp2889 2 None None None 54297293 Common rnhA hypothetical protein lpp1338 177 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 54298990 Common atpF hypothetical protein lpp3057 115 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 54297016 Common - hypothetical protein lpp1058 22 None None None 54297741 Common - hypothetical protein lpp1792 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 54297685 Common - hypothetical protein lpp1736 21 COG3698 COG3698, Predicted periplasmic protein Function unknown 54297892 Pathogen - hypothetical protein lpp1947 1 None None None 54298174 Common - hypothetical protein lpp2231 101 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 54296982 Common - hypothetical protein lpp1023 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 54297368 Common relA GTP pyrophosphokinase lpp1413 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 54296155 Common lvhB10 Legionella vir homologue protein lpp0178 59 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 54296968 Common - hypothetical protein lpp1009 111 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 54297425 Common lssY Legionella secretion system protein Y lpp1470 159 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 54298274 Common - hypothetical protein lpp2332 48 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 54297840 Common - hypothetical protein lpp1892 97 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 54296816 Common - hypothetical protein lpp0856 111 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54298515 Common sidC SidC protein (substrate of the Dot/Icm system) lpp2579 4 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 54297974 Common - hypothetical protein lpp2029 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 54296664 Common hslU ATP-dependent protease ATP-binding subunit lpp0695 216 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 54298187 Common rne Ribonuclease E lpp2244 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 54298159 Common ack acetate kinase lpp2216 162 COG0282 ackA, Acetate kinase Energy production and conversion 54296066 Common - hypothetical protein lpp0084 2 None None None 54298623 Common - hypothetical protein lpp2687 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 54298231 Common djlA Dna-J like membrane chaperone protein lpp2289 68 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 54297232 Common - hypothetical protein lpp1277 105 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 54297455 Common - hypothetical protein lpp1500 61 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 54297100 Common - hypothetical protein lpp1145 207 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 54298433 Common - hypothetical protein lpp2497 45 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 54297853 Common - hypothetical protein lpp1905 36 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 54296605 Common - hypothetical protein lpp0636 128 COG1678 COG1678, Putative transcriptional regulator Transcription 54298528 Common - hypothetical protein lpp2592 3 None None None 54297612 Common - hypothetical protein lpp1663 15 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 54298126 Pathogen - hypothetical protein lpp2183 1 None None None 54298799 Pathogen - hypothetical protein lpp2863 1 None None None 54298890 Pathogen - hypothetical protein lpp2957 1 None None None 54298759 Common nuoN NADH dehydrogenase subunit N lpp2823 209 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 54298966 Common - major outer membrane protein precursor lpp3033 2 None None None 54297052 Pathogen - hypothetical protein lpp1094 1 None None None 54298534 Common aspB hypothetical protein lpp2598 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 54297030 Pathogen - hypothetical protein lpp1072 1 None None None 54297265 Common - hypothetical protein lpp1310 114 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 54298329 Common - hypothetical protein lpp2388 14 None None None 54298606 Common mraY Phospho-N-acetylmuramoyl-pentapeptide- transferase lpp2670 219 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 54298693 Common sspA hypothetical protein lpp2757 111 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 54298292 Pathogen cecA Chemiosmotic efflux system C protein A lpp2350 1 None None None 54296873 Pathogen - hypothetical protein lpp0914 1 None None None 54298900 Common - hypothetical protein lpp2967 2 None None None 54297946 Common - hypothetical protein lpp2001 107 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 54297757 Common - D-tyrosyl-tRNA deacylase lpp1808 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 54296681 Pathogen - hypothetical protein lpp0712 1 None None None 54296029 Pathogen - hypothetical protein lpp0046 1 None None None 54296179 Common - hypothetical protein lpp0203 52 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 54296558 Common - hypothetical protein lpp0589 8 None None None 54296193 Common - hypothetical protein lpp0219 185 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 54297938 Common - hypothetical protein lpp1993 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 54298336 Common - hypothetical protein lpp2395 21 None None None 54298322 Common - hypothetical protein lpp2381 20 None None None 54297250 Common accD hypothetical protein lpp1295 205 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 54296850 Common - hypothetical protein lpp0891 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 54298790 Common aroE shikimate 5-dehydrogenase lpp2854 220 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 54297791 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein lpp1842 160 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 54297659 Common IscS hypothetical protein lpp1710 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 54296704 Common glnE hypothetical protein lpp0735 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 54296656 Common - hypothetical protein lpp0687 24 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 54297085 Pathogen - hypothetical protein lpp1130 1 None None None 54298819 Common - transposase/IS protein lpp2885 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 54298633 Common - hypothetical protein lpp2697 100 None None None 54298921 Common - hypothetical protein lpp2988 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 54297385 Common bioH Biotin biosynthesis protein BioH lpp1430 163 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54297573 Common - hypothetical protein lpp1624 121 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54298997 Common - hypothetical protein lpp3064 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 54296184 Pathogen - hypothetical protein lpp0209 1 None None None 54296922 Pathogen - hypothetical protein lpp0963 1 None None None 54296867 Common - hypothetical protein lpp0908 52 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 54296834 Common mreD Rod shape-determining protein MreD lpp0875 23 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 54298775 Common lepA effector protein A, substrate of the Dot/Icm secretion system lpp2839 15 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 54296467 Pathogen - hypothetical protein lpp0498 1 None None None 54297337 Common - hypothetical protein lpp1382 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 54298394 Pathogen sdbC SdbC proteins, putative substrate of the Dot/Icm system lpp2458 1 None None None 54296633 Pathogen - hypothetical protein lpp0664 1 None None None 54297018 Common - hypothetical protein lpp1060 26 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 54297553 Common - hypothetical protein lpp1603 2 None None None 54297714 Common recA RecA protein lpp1765 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 54298000 Pathogen - hypothetical protein lpp2057 1 None None None 54298288 Common - hypothetical protein lpp2346 3 COG4244 COG4244, Predicted membrane protein Function unknown 54298706 Common thrS Threonyl tRNA synthetase lpp2770 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54296878 Common ccmB heme exporter protein CcmB lpp0919 52 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 54296665 Pathogen - hypothetical protein lpp0696 1 None None None 54298344 Common - hypothetical protein lpp2403 8 None None None 54296224 Pathogen - hypothetical protein lpp0250 1 None None None 54298098 Common - hypothetical protein lpp2155 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 54298083 Pathogen - hypothetical protein lpp2140 2 None None None 54297417 Pathogen - hypothetical protein lpp1462 1 None None None 54298302 Common - hypothetical protein lpp2360 133 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 54297489 Common ruvB Holliday junction DNA helicase B lpp1534 227 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 54298077 Common - hypothetical protein lpp2134 34 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 54297340 Common ubiA prenyltransferase lpp1385 162 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 54296024 Common - hypothetical protein lpp0041 23 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 54298922 Common - hypothetical protein lpp2989 159 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 54297206 Common ruvA holliday junction DNA helicase lpp1251 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 54297674 Common fliE Flagellar hook-basal body complex protein lpp1725 76 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 54298736 Pathogen - hypothetical protein lpp2800 1 None None None 54297824 Common - hypothetical protein lpp1876 47 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54296640 Common - hypothetical protein lpp0671 3 None None None 54296859 Common - hypothetical protein lpp0900 5 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 54296597 Common tyrS tyrosyl-tRNA synthetase lpp0628 243 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54296436 Common ffh hypothetical protein lpp0467 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 54297128 Pathogen - hypothetical protein lpp1173 1 None None None 54295999 Pathogen - hypothetical protein lpp0016 1 None None None 54297750 Common - hypothetical protein lpp1801 51 None None None 54298955 Common cysK hypothetical protein lpp3022 218 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 54296476 Common icmT hypothetical protein lpp0507 4 None None None 54296283 Common - hypothetical protein lpp0312 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 54298757 Common nusA transcription elongation factor NusA lpp2821 216 COG0195 NusA, Transcription elongation factor Transcription 54297065 Pathogen - hypothetical protein lpp1110 1 None None None 54296157 Common lvhD4 Legionella vir homologue protein lpp0180 70 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 54297786 Common - GTP-binding protein LepA lpp1837 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 54298802 Pathogen - hypothetical protein lpp2867 1 None None None 54298882 Common gidB hypothetical protein lpp2949 205 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 54298053 Common - hypothetical protein lpp2110 134 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 54298516 Common lmxF hypothetical protein lpp2580 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 54298979 Common psd Phosphatidylserine decarboxylase lpp3046 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 54297506 Common - hypothetical protein lpp1551 2 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 54296211 Common - hypothetical protein lpp0237 14 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 54297709 Common - hypothetical protein lpp1760 184 COG0583 LysR, Transcriptional regulator Transcription 54296520 Common - hypothetical protein lpp0551 24 COG5553 COG5553, Predicted metal-dependent enzyme of the double-stranded beta helix superfamily General function prediction only 54296647 Pathogen - hypothetical protein lpp0678 1 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 54298105 Common - hypothetical protein lpp2162 127 COG0432 COG0432, Uncharacterized conserved protein Function unknown 54298111 Common - hypothetical protein lpp2168 2 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 54296723 Common tolC hypothetical protein lpp0754 128 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54298378 Common - hypothetical protein lpp2442 8 None None None 54296124 Common - hypothetical protein lpp0143 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 54296086 Pathogen - hypothetical protein lpp0104 1 None None None 54296060 Common - hypothetical protein lpp0078 165 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 54296642 Common - hypothetical protein lpp0673 43 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 54298404 Common - hypothetical protein lpp2468 18 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 54298872 Common nth Endonuclease III lpp2939 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 54298133 Common - hypothetical protein lpp2190 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 54297395 Pathogen - hypothetical protein lpp1440 1 None None None 54297435 Common pilC pilus assembly protein PilC lpp1480 153 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 54296116 Common - hypothetical protein lpp0135 124 COG4986 COG4986, ABC-type anion transport system, duplicated permease component Inorganic ion transport and metabolism 54298218 Pathogen - hypothetical protein lpp2276 1 None None None 54298222 Common - hypothetical protein lpp2280 174 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 54298656 Common - hypothetical protein lpp2720 18 COG2267 PldB, Lysophospholipase Lipid metabolism 54296904 Pathogen - hypothetical protein lpp0945 1 None None None 54297595 Common purF amidophosphoribosyltransferase lpp1646 236 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 54296161 Pathogen - hypothetical protein lpp0184 1 None None None 54297116 Common - hypothetical protein lpp1161 6 COG2510 COG2510, Predicted membrane protein Function unknown 54297476 Common - hypothetical protein lpp1521 85 COG1814 COG1814, Uncharacterized membrane protein Function unknown 54297310 Common - hypothetical protein lpp1355 216 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 54296956 Common - hypothetical protein lpp0997 17 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 54297159 Common cydA cytochrome d ubiquinol oxidase subunit I lpp1204 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 54298499 Common - hypothetical protein lpp2563 162 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 54297807 Common - hypothetical protein lpp1858 5 None None None 54296728 Common - hypothetical protein lpp0759 3 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 54296292 Common - hypothetical protein lpp0321 65 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 54298444 Common - hypothetical protein lpp2508 67 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 54297196 Common - hypothetical protein lpp1241 4 None None None 54296942 Pathogen - hypothetical protein lpp0983 1 None None None 54296177 Common - hypothetical protein lpp0201 52 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 54296393 Common - hypothetical protein lpp0422 188 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54298942 Pathogen - hypothetical protein lpp3009 1 None None None 54297839 Common - hypothetical protein lpp1891 76 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 54296466 Common - hypothetical protein lpp0497 130 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 54296988 Pathogen - hypothetical protein lpp1029 1 None None None 54298830 Common - hypothetical protein lpp2897 110 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 54298427 Pathogen - hypothetical protein lpp2491 1 None None None 54296485 Common icmK/dotH hypothetical protein lpp0516 10 None None None 54296973 Common - hypothetical protein lpp1014 128 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 54296336 Common efp hypothetical protein lpp0365 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 54298738 Common dnaX DNA polymerase III, gamma and tau subunits lpp2802 243 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 54295987 Common gyrB DNA gyrase, subunit B (type II topoisomerase) lpp0004 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 54296733 Common hutG hypothetical protein lpp0764 122 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 54296794 Common - hypothetical protein lpp0834 21 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 54298746 Pathogen - hypothetical protein lpp2810 1 None None None 54297609 Common - hypothetical protein lpp1660 171 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 54296445 Common - hypothetical protein lpp0476 55 COG3346 COG3346, Uncharacterized conserved protein Function unknown 54296885 Common - hypothetical protein lpp0926 54 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 54296203 Common - hypothetical protein lpp0229 136 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 54297960 Common recG ATP-dependent DNA helicase RecG lpp2015 212 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 54297378 Common - hypothetical protein lpp1423 207 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 54296458 Common - hypothetical protein lpp0489 12 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 54297464 Common - UDP-2,3-diacylglucosamine hydrolase lpp1509 79 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 54297048 Common - hypothetical protein lpp1090 85 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 54297371 Common - hypothetical protein lpp1416 6 COG4255 COG4255, Uncharacterized protein conserved in bacteria Function unknown 54297744 Pathogen - hypothetical protein lpp1795 4 None None None 54297024 Pathogen - hypothetical protein lpp1066 1 None None None 54296546 Pathogen - hypothetical protein lpp0577 1 None None None 54296813 Common - hypothetical protein lpp0853 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 54297534 Common - hypothetical protein lpp1584 45 COG2320 GrpB, Uncharacterized conserved protein Function unknown 54297798 Pathogen - hypothetical protein lpp1849 1 None None None 54297070 Common - hypothetical protein lpp1115 24 None None None 54297322 Common - hypothetical protein lpp1367 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 54297619 Common - hypothetical protein lpp1670 119 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 54296415 Common - hypothetical protein lpp0445 9 COG2170 COG2170, Uncharacterized conserved protein Function unknown 54297176 Common - hypothetical protein lpp1221 7 None None None 54296561 Common - hypothetical protein lpp0592 44 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 54297924 Common hisC hypothetical protein lpp1979 232 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 54298169 Common - hypothetical protein lpp2226 20 COG5472 COG5472, Predicted small integral membrane protein Function unknown 54296168 Common - hypothetical protein lpp0191 11 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 54298786 Pathogen - hypothetical protein lpp2850 1 None None None 54298455 Pathogen - hypothetical protein lpp2519 1 None None None 54298379 Pathogen - hypothetical protein lpp2443 1 None None None 54298150 Common - hypothetical protein lpp2207 22 None None None 54296714 Common - hypothetical protein lpp0745 20 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 54296111 Common gcsA glycine dehydrogenase subunit 1 lpp0130 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 54297414 Common lpd Lipoamide dehydrogenase lpp1459 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 54298125 Common - hypothetical protein lpp2182 218 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54298253 Common - hypothetical protein lpp2311 65 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 54297480 Common thiG thiazole synthase lpp1525 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 54296994 Common - hypothetical protein lpp1035 65 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 54298191 Common - hypothetical protein lpp2249 74 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 54296629 Common - hypothetical protein lpp0660 76 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 54296402 Common dapF Diaminopimelate epimerase lpp0431 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 54298010 Common - hypothetical protein lpp2067 18 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 54297725 Common - hypothetical protein lpp1776 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 54296569 Common sucD succinyl-CoA synthetase, alpha subunit lpp0600 214 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 54297284 Common mrdA penicillin-binding protein 2 lpp1329 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 54295996 Common - hypothetical protein lpp0013 148 COG1741 COG1741, Pirin-related protein General function prediction only 54296844 Pathogen - hypothetical protein lpp0885 1 None None None 54298581 Common - hypothetical protein lpp2645 7 None None None 54298009 Common - hypothetical protein lpp2066 34 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54298480 Common - hypothetical protein lpp2544 34 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 54298691 Common - hypothetical protein lpp2755 221 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 54296378 Common rpsN 30S ribosomal protein S14 lpp0407 211 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 54298065 Common - hypothetical protein lpp2122 3 None None None 54298070 Common - hypothetical protein lpp2127 35 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 54298134 Common - hypothetical protein lpp2191 26 COG3686 COG3686, Predicted membrane protein Function unknown 54298069 Pathogen - hypothetical protein lpp2126 1 None None None 54296773 Common iraB di/tripeptide transporter homolog IraB lpp0812 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 54297353 Common - hypothetical protein lpp1398 230 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 54296380 Common rplF 50S ribosomal protein L6 lpp0409 226 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 54298867 Common glmU Bifunctional GlmU protein, UDP-N-acetylglucosamine pyrophosphorylase and Glucosamine-1-phosphate N-acetyltransferase lpp2934 233 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 54298773 Common secG preprotein translocase subunit SecG lpp2837 63 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 54296144 Pathogen lvrB Legionella vir region protein lpp0167 1 None None None 54296536 Common cdsA phosphatidate cytidylyltransferase lpp0567 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 54297094 Pathogen - hypothetical protein lpp1139 1 None None None 54298916 Common - hypothetical protein lpp2983 42 COG3153 COG3153, Predicted acetyltransferase General function prediction only 54297904 Common - hypothetical protein lpp1959 13 COG5184 ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins Cell division and chromosome partitioning / Cytoskeleton 54297444 Common - hypothetical protein lpp1489 93 COG4121 COG4121, Uncharacterized conserved protein Function unknown 54297626 Common pyrH Uridylate kinase (UK) (Uridine monophosphate kinase) lpp1677 237 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 54296426 Pathogen - hypothetical protein lpp0456 1 None None None 54297894 Common - hypothetical protein lpp1949 72 COG1309 AcrR, Transcriptional regulator Transcription 54297719 Common - hypothetical protein lpp1770 71 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 54296080 Common - hypothetical protein lpp0098 19 None None None 54298103 Common - hypothetical protein lpp2160 131 COG1881 COG1881, Phospholipid-binding protein General function prediction only 54297582 Pathogen - hypothetical protein lpp1633 1 None None None 54298272 Common - hypothetical protein lpp2330 11 None None None 54298395 Pathogen - hypothetical protein lpp2459 2 None None None 54297112 Common - hypothetical protein lpp1157 218 COG3961 COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only 54296741 Common - hypothetical protein lpp0780 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 54296325 Common - hypothetical protein lpp0354 39 COG3287 COG3287, Uncharacterized conserved protein Function unknown 54296256 Common - hypothetical protein lpp0283 109 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 54298722 Common - hypothetical protein lpp2786 45 COG3245 CycB, Cytochrome c5 Energy production and conversion 54296479 Pathogen icmQ hypothetical protein lpp0510 2 None None None 54298333 Common - hypothetical protein lpp2392 24 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 54297984 Pathogen - hypothetical protein lpp2039 1 None None None 54297640 Common fadE acyl-CoA dehydrogenase lpp1691 152 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 54298002 Common - hypothetical protein lpp2059 2 None None None 54297426 Pathogen lssZ Legionella secretion system protein Z lpp1471 1 None None None 54296364 Common rpsJ 30S ribosomal protein S10 lpp0393 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 54296680 Common - hypothetical protein lpp0711 123 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 54298476 Common hypB hydrogenase nickel incorporation protein HypB lpp2540 148 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 54296699 Common - hypothetical protein lpp0730 82 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 54298569 Common - hypothetical protein lpp2633 174 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 54296387 Common rpsM 30S ribosomal protein S13 lpp0416 216 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 54296153 Common lvhB8 Legionella vir homologue protein lpp0176 19 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 54297539 Common - hypothetical protein lpp1589 203 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 54298471 Common - hypothetical protein lpp2535 32 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 54296172 Common - hypothetical protein lpp0195 9 COG5340 COG5340, Predicted transcriptional regulator Transcription 54296767 Common - hypothetical protein lpp0806 120 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 54298258 Common - hypothetical protein lpp2316 111 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54296708 Common - hypothetical protein lpp0739 145 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 54297589 Pathogen - hypothetical protein lpp1640 1 None None None 54296716 Common - hypothetical protein lpp0747 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 54298033 Common - hypothetical protein lpp2090 10 None None None 54296901 Common - hypothetical protein lpp0942 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 54296048 Common hipB hypothetical protein lpp0065 16 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 54296349 Common folA dihydrofolate reductase FolA lpp0378 148 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 54298560 Common - hypothetical protein lpp2624 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 54298537 Common - hypothetical protein lpp2601 19 COG2346 COG2346, Truncated hemoglobins General function prediction only 54296947 Pathogen - hypothetical protein lpp0988 1 None None None 54297178 Common hemF coproporphyrinogen III oxidase lpp1223 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 54296582 Common sugE hypothetical protein lpp0613 145 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 54297911 Common - hypothetical protein lpp1966 151 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 54296164 Common - hypothetical protein lpp0187 36 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 54297530 Common - hypothetical protein lpp1578 46 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 54298309 Common - hypothetical protein lpp2367 14 None None None 54296512 Common rpmG 50S ribosomal protein L33 lpp0543 55 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 54296407 Common - hypothetical protein lpp0436 66 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 54297701 Common fliQ Flagellar biosynthetic protein FliQ lpp1752 81 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 54297645 Common - hypothetical protein lpp1696 166 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 54296927 Common - hypothetical protein lpp0968 6 COG3418 COG3418, Flagellar biosynthesis/type III secretory pathway chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 54297292 Common - short chain dehydrogenase lpp1337 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54296678 Common - hypothetical protein lpp0709 37 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 54298797 Common - hypothetical protein lpp2861 15 COG3435 COG3435, Gentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 54297829 Common - hypothetical protein lpp1881 31 COG3101 COG3101, Uncharacterized protein conserved in bacteria Function unknown 54296299 Common - hypothetical protein lpp0328 2 None None None 54297245 Common - hypothetical protein lpp1290 12 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 54296913 Common - hypothetical protein lpp0954 6 None None None 54296611 Common glnB Nitrogen regulatory protein lpp0642 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 54296781 Common - hypothetical protein lpp0820 155 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 54296338 Common ppk polyphosphate kinase lpp0367 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 54296576 Common prs Ribose-phosphate pyrophosphokinase lpp0607 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 54297299 Common trmU hypothetical protein lpp1344 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 54297712 Common alaS alanyl-tRNA synthetase lpp1763 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54298224 Pathogen - hypothetical protein lpp2282 1 None None None 54297351 Common - hypothetical protein lpp1396 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 54297358 Common - hypothetical protein lpp1403 20 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 54296053 Pathogen - hypothetical protein lpp0071 1 None None None 54297027 Common - hypothetical protein lpp1069 21 None None None 54297832 Pathogen - hypothetical protein lpp1884 1 None None None 54297173 Common - hypothetical protein lpp1218 42 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 54298197 Common grx hypothetical protein lpp2255 126 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 54296505 Common - hypothetical protein lpp0536 169 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 54298368 Common - hypothetical protein lpp2432 22 COG0439 AccC, Biotin carboxylase Lipid metabolism 54298572 Pathogen - hypothetical protein lpp2636 1 None None None 54297944 Pathogen - hypothetical protein lpp1999 1 None None None 54296460 Common - hypothetical protein lpp0491 8 None None None 54297616 Pathogen - hypothetical protein lpp1667 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54298547 Common - hypothetical protein lpp2611 86 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 54298618 Common - hypothetical protein lpp2682 121 COG0795 COG0795, Predicted permeases General function prediction only 54296753 Common - hypothetical protein lpp0792 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 54297795 Common - hypothetical protein lpp1846 124 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 54298279 Common - hypothetical protein lpp2337 150 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 54297465 Common - hypothetical protein lpp1510 89 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 54299010 Common rpmH 50S ribosomal protein L34 lpp3077 191 None None None 54298163 Common - hypothetical protein lpp2220 30 COG3310 COG3310, Uncharacterized protein conserved in bacteria Function unknown 54298590 Common - hypothetical protein lpp2654 7 COG3428 COG3428, Predicted membrane protein Function unknown 54297516 Common - transposase/IS protein lpp1564 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 54297107 Common - hypothetical protein lpp1152 189 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 54297366 Common - hypothetical protein lpp1411 2 None None None 54296820 Common nadA quinolinate synthetase lpp0861 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 54297161 Common pyrE orotate phosphoribosyltransferase lpp1206 108 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 54296818 Pathogen - hypothetical protein lpp0859 1 None None None 54298930 Common tatC hypothetical protein lpp2997 203 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 54297406 Common - hypothetical protein lpp1451 7 None None None 54297487 Common tolQ hypothetical protein lpp1532 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 54296888 Common - hypothetical protein lpp0929 83 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 54296506 Pathogen dotV hypothetical protein lpp0537 2 None None None 54296989 Pathogen - hypothetical protein lpp1030 2 None None None 54296090 Common - ribose-5-phosphate isomerase A lpp0108 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 54297820 Common - hypothetical protein lpp1872 38 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 54297104 Pathogen - hypothetical protein lpp1149 1 None None None 54298024 Pathogen - hypothetical protein lpp2081 1 None None None 54296939 Common - hypothetical protein lpp0980 100 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 54298351 Common - hypothetical protein lpp2410 65 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 54296285 Common - hypothetical protein lpp0314 240 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 54296395 Common - hypothetical protein lpp0424 2 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54296620 Common - hypothetical protein lpp0651 152 COG1959 COG1959, Predicted transcriptional regulator Transcription 54298060 Common - hypothetical protein lpp2117 36 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 54296952 Common pilQ type IV pilus (Tfp) assembly protein PilQ lpp0993 140 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 54298361 Pathogen - hypothetical protein lpp2424 1 None None None 54297490 Common rpoE Sigma factor RpoE (sigma 24) lpp1535 166 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 54297857 Pathogen - hypothetical protein lpp1912 1 None None None 54296233 Common qxtA hypothetical protein lpp0259 167 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 54296207 Pathogen - hypothetical protein lpp0233 1 None None None 54297211 Common - hypothetical protein lpp1256 91 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 54297936 Common rpoZ RNA polymerase omega subunit lpp1991 114 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 54298677 Pathogen icmV intracellular multiplication protein IcmV lpp2741 2 None None None 54297303 Common fabH 3-oxoacyl-[acyl-carrier-protein] synthase III lpp1348 224 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 54297010 Common - hypothetical protein lpp1051 8 None None None 54298530 Pathogen - hypothetical protein lpp2594 1 None None None 54298875 Common - hypothetical protein lpp2942 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 54297080 Pathogen - hypothetical protein lpp1125 1 None None None 54296724 Common - hypothetical protein lpp0755 156 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 54297693 Common motB flagellar motor protein MotD lpp1744 162 COG1360 MotB, Flagellar motor protein Cell motility and secretion 54296083 Common - hypothetical protein lpp0101 12 None None None 54298630 Common enhA enhanced entry protein EnhA lpp2694 7 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 54296331 Pathogen - hypothetical protein lpp0360 1 None None None 54298637 Common - hypothetical protein lpp2701 157 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 54296093 Pathogen - hypothetical protein lpp0112 1 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 54297183 Common flgF flagellar basal body rod protein FlgF lpp1228 125 COG4787 FlgF, Flagellar basal body rod protein Cell motility and secretion 54297274 Common - hypothetical protein lpp1319 17 None None None 54297819 Common - hypothetical protein lpp1871 175 COG0714 COG0714, MoxR-like ATPases General function prediction only 54298713 Common - hypothetical protein lpp2777 8 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 54296275 Common sidE SidE protein, substrate of the Dot/Icm system lpp0304 4 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 54298828 Common - hypothetical protein lpp2895 14 None None None 54297651 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B lpp1702 210 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 54297543 Common - hypothetical protein lpp1593 88 COG0585 COG0585, Uncharacterized conserved protein Function unknown 54297001 Pathogen - hypothetical protein lpp1042 1 None None None 54296016 Common - hypothetical protein lpp0033 2 None None None 54298416 Pathogen - hypothetical protein lpp2480 1 None None None 54298935 Common rho transcription termination factor Rho lpp3002 202 COG1158 Rho, Transcription termination factor Transcription 54297223 Common trpB tryptophan synthase subunit beta lpp1268 227 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 54298314 Common helC HelC protein lpp2373 49 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54298959 Common himD hypothetical protein lpp3026 199 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 54297339 Common - hypothetical protein lpp1384 2 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 54296832 Common mreB Rod shape-determining protein MreB lpp0873 234 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 54298518 Common lprN hypothetical protein lpp2582 127 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54298388 Common - outer membrane protease lpp2452 12 COG4571 OmpT, Outer membrane protease Cell envelope biogenesis, outer membrane 54296883 Common ccmG cytochrome C biogenesis protein lpp0924 122 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 54296248 Common - hypothetical protein lpp0275 69 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 54298264 Common - hypothetical protein lpp2322 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54297148 Common - hypothetical protein lpp1193 169 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 54298096 Common - hypothetical protein lpp2153 15 None None None 54296469 Common - hypothetical protein lpp0500 145 COG1733 COG1733, Predicted transcriptional regulators Transcription 54298327 Pathogen - hypothetical protein lpp2386 1 None None None 54297508 Common - hypothetical protein lpp1553 95 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 54298081 Common - hypothetical protein lpp2138 101 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 54296474 Pathogen - hypothetical protein lpp0505 1 None None None 54296501 Common proA zinc metalloproteinase precursor lpp0532 43 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 54296488 Pathogen icmC/dotE hypothetical protein lpp0519 2 None None None 54297551 Common - 3-oxoacyl-(acyl carrier protein) synthase III lpp1601 204 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 54297456 Common hisS histidyl-tRNA synthetase lpp1501 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54298704 Common rpmI 50S ribosomal protein L35 lpp2768 148 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 54296865 Common - hypothetical protein lpp0906 82 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 54298031 Pathogen - hypothetical protein lpp2088 1 None None None 54296595 Common - hypothetical protein lpp0626 44 COG0700 SpmB, Uncharacterized membrane protein Function unknown 54298810 Common typA hypothetical protein lpp2875 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 54297778 Common clpP ATP-dependent Clp protease proteolytic subunit lpp1829 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 54298800 Pathogen - hypothetical protein lpp2865 1 None None None 54298928 Common ksgA dimethyladenosine transferase lpp2995 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 54296278 Common - hypothetical protein lpp0307 186 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54297752 Common glyS glycyl-tRNA synthetase beta chain lpp1803 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 54296022 Common - hypothetical protein lpp0039 38 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54298131 Common - hypothetical protein lpp2188 75 COG3000 ERG3, Sterol desaturase Lipid metabolism 54296875 Pathogen - hypothetical protein lpp0916 1 None None None 54297050 Pathogen - hypothetical protein lpp1092 1 None None None 54298247 Common - hypothetical protein lpp2305 170 COG0344 COG0344, Predicted membrane protein Function unknown 54298240 Common - hypothetical protein lpp2298 27 COG2128 COG2128, Uncharacterized conserved protein Function unknown 54298715 Common - hypothetical protein lpp2779 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 54297079 Common - hypothetical protein lpp1124 106 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 54297955 Common hemE Uroporphyrinogen decarboxylase lpp2010 182 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 54297063 Common - hypothetical protein lpp1108 2 COG2267 PldB, Lysophospholipase Lipid metabolism 54296006 Common - hypothetical protein lpp0023 23 COG4539 COG4539, Predicted membrane protein Function unknown 54297520 Common plaB phospholipase lpp1568 9 None None None 54296857 Common - hypothetical protein lpp0898 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 54298766 Common nuoG NADH dehydrogenase subunit G lpp2830 195 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 54296672 Common xthA hypothetical protein lpp0703 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 54298615 Pathogen - hypothetical protein lpp2679 2 None None None 54298977 Common - hypothetical protein lpp3044 231 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 54298152 Common - hypothetical protein lpp2209 10 None None None 54296131 Common sdhB SdhB protein, substrate of the Dot/Icm system lpp0150 5 None None None 54298664 Common dotD lipoprotein DotD lpp2728 4 None None None 54296683 Common - hypothetical protein lpp0714 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 54298145 Pathogen - hypothetical protein lpp2202 1 None None None 54296068 Common uvrB excinuclease ABC subunit B lpp0086 231 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 54296603 Common - hypothetical protein lpp0634 36 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 54298431 Common - hypothetical protein lpp2495 26 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 54298621 Common holC hypothetical protein lpp2685 59 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 54297349 Common - hypothetical protein lpp1394 217 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 54296902 Pathogen - hypothetical protein lpp0943 1 None None None 54298523 Pathogen - hypothetical protein lpp2587 1 None None None 54297923 Pathogen - hypothetical protein lpp1978 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 54296739 Pathogen - hypothetical protein lpp0778 1 None None None 54298968 Common pyrC dihydroorotase lpp3035 100 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 54297252 Common - hypothetical protein lpp1297 3 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 54297657 Common - hypothetical protein lpp1708 162 COG0316 IscA, Uncharacterized conserved protein Function unknown 54297331 Common rpsA 30S ribosomal protein S1 lpp1376 215 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 54298511 Pathogen - hypothetical protein lpp2575 1 None None None 54297408 Pathogen - hypothetical protein lpp1453 1 None None None 54298189 Common hepA ATP-dependent helicase HepA lpp2247 145 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 54298128 Common - hypothetical protein lpp2185 201 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 54297915 Pathogen - hypothetical protein lpp1970 1 COG3788 COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily General function prediction only 54296312 Common - hypothetical protein lpp0341 170 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 54297593 Common purN Phosphoribosylglycinamide formyltransferase lpp1644 222 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 54297319 Common - hypothetical protein lpp1364 32 COG3298 COG3298, Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA replication, recombination, and repair 54298492 Common - hypothetical protein lpp2556 48 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 54297102 Pathogen - hypothetical protein lpp1147 1 None None None 54298899 Common - hypothetical protein lpp2966 82 COG1279 COG1279, Lysine efflux permease General function prediction only 54296962 Pathogen - hypothetical protein lpp1003 1 COG1822 COG1822, Predicted archaeal membrane protein Function unknown 54297566 Common - hypothetical protein lpp1617 78 COG3038 CybB, Cytochrome B561 Energy production and conversion 54297308 Common - hypothetical protein lpp1353 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 54298961 Common - hypothetical protein lpp3028 200 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 54296195 Common - hypothetical protein lpp0221 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 54296425 Common - hypothetical protein lpp0455 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 54298748 Common ppa Inorganic pyrophosphatase lpp2812 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 54297234 Common - hypothetical protein lpp1279 61 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54296924 Common - hypothetical protein lpp0965 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 54298608 Common - hypothetical protein lpp2672 41 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 54296662 Common deoB phosphopentomutase lpp0693 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 54297198 Common sfcA malate oxidoreductase lpp1243 202 COG0281 SfcA, Malic enzyme Energy production and conversion 54298320 Common - hypothetical protein lpp2379 9 None None None 54297083 Common - hypothetical protein lpp1128 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54296297 Common - hypothetical protein lpp0326 18 COG1289 COG1289, Predicted membrane protein Function unknown 54297867 Common - hypothetical protein lpp1922 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 54297288 Common - hypothetical protein lpp1333 81 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 54298550 Pathogen - hypothetical protein lpp2614 1 None None None 54297046 Common - hypothetical protein lpp1088 132 COG0582 XerC, Integrase DNA replication, recombination, and repair 54297683 Common infA Translation initiation factor IF-1 lpp1734 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 54297992 Pathogen - hypothetical protein lpp2048 1 None None None 54298422 Pathogen - hypothetical protein lpp2486 1 None None None 54298957 Pathogen - hypothetical protein lpp3024 1 None None None 54296992 Pathogen - hypothetical protein lpp1033 3 COG5371 COG5371, Golgi nucleoside diphosphatase Carbohydrate transport and metabolism / Posttranslational modification, protein turnover, chaperones 54297282 Common rnhB hypothetical protein lpp1327 234 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 54297873 Pathogen - hypothetical protein lpp1928 1 None None None 54297376 Pathogen - hypothetical protein lpp1421 1 None None None 54296166 Common - hypothetical protein lpp0189 46 COG1738 COG1738, Uncharacterized conserved protein Function unknown 54296627 Common - hypothetical protein lpp0658 227 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 54298914 Pathogen - hypothetical protein lpp2981 1 None None None 54295985 Common dnaN DNA polymerase III, beta chain lpp0002 213 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 54296307 Pathogen - hypothetical protein lpp0336 1 None None None 54298642 Common pth peptidyl-tRNA hydrolase lpp2706 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 54298457 Pathogen - hypothetical protein lpp2521 1 None None None 54297691 Common prfB hypothetical protein lpp1742 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 54296807 Common birA biotin-[acetylCoA carboxylase] holoenzyme synthetase and biotin operon repressor lpp0847 221 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 54297022 Common - hypothetical protein lpp1064 17 None None None 54297532 Common - hypothetical protein lpp1582 86 COG0789 SoxR, Predicted transcriptional regulators Transcription 54298788 Pathogen - hypothetical protein lpp2852 1 None None None 54296122 Common acsB hypothetical protein lpp0141 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 54297610 Common putA bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase lpp1661 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 54297002 Pathogen - hypothetical protein lpp1043 1 None None None 54296567 Common sucB dihydrolipoamide succinyltransferase, E2 subunit lpp0598 196 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 54296483 Pathogen icmM/dotJ hypothetical protein lpp0514 1 None None None 54296008 Common rcp palmitoyl transferase for Lipid A lpp0025 14 None None None 54298220 Common - hypothetical protein lpp2278 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 54298055 Common - hypothetical protein lpp2112 2 None None None 54296529 Common - hypothetical protein lpp0560 5 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 54297412 Common - hypothetical protein lpp1457 205 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54298018 Common ceaC Chemiosmotic efflux system protein C-like protein lpp2075 92 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54298998 Common - hypothetical protein lpp3065 148 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 54296342 Common - acyl-CoA dehydrogenase lpp0371 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 54297668 Common - hypothetical protein lpp1719 55 COG3164 COG3164, Predicted membrane protein Function unknown 54297676 Common fleS hypothetical protein lpp1727 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 54298489 Common radC DNA repair protein RadC lpp2553 177 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 54297204 Common - hypothetical protein lpp1249 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 54296548 Pathogen - hypothetical protein lpp0579 1 None None None 54298208 Common motA2 flagellar motor protein MotA lpp2266 108 COG1291 MotA, Flagellar motor component Cell motility and secretion 54297239 Common - hypothetical protein lpp1284 4 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 54296443 Common lidJ hypothetical protein lpp0474 13 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 54298880 Pathogen - hypothetical protein lpp2947 1 None None None 54296792 Common - hypothetical protein lpp0832 2 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 54296553 Common - hypothetical protein lpp0584 21 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 54297962 Common - hypothetical protein lpp2017 206 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 54296915 Common - hypothetical protein lpp0956 2 COG3031 PulC, Type II secretory pathway, component PulC Intracellular trafficking and secretion 54297617 Common umuC hypothetical protein lpp1668 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 54297324 Common glpK Glycerol kinase lpp1369 178 COG0554 GlpK, Glycerol kinase Energy production and conversion 54298079 Common - hypothetical protein lpp2136 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 54296584 Common - hypothetical protein lpp0615 5 None None None 54296975 Common mfd Transcription-repair coupling factor lpp1016 234 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 54298824 Common - hypothetical protein lpp2891 160 COG2183 Tex, Transcriptional accessory protein Transcription 54298944 Pathogen - hypothetical protein lpp3011 1 None None None 54297884 Pathogen - hypothetical protein lpp1939 2 None None None 54298117 Common - hypothetical protein lpp2174 119 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 54296074 Common ubiH hypothetical protein lpp0092 118 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 54297114 Common - hypothetical protein lpp1159 32 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 54298832 Common - hypothetical protein lpp2899 226 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 54298118 Pathogen - hypothetical protein lpp2175 1 None None None 54298072 Common - hypothetical protein lpp2129 155 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 54296958 Common ileS isoleucyl-tRNA synthetase lpp0999 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54296049 Common - hypothetical protein lpp0067 7 None None None 54298649 Common - hypothetical protein lpp2713 100 COG1485 COG1485, Predicted ATPase General function prediction only 54296908 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase lpp0949 142 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 54296409 Common fur Ferric uptake regulation protein lpp0438 196 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 54298684 Common - hypothetical protein lpp2748 10 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 54298982 Common - hypothetical protein lpp3049 41 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 54297478 Common - hypothetical protein lpp1523 61 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 54297154 Common hisB imidazole glycerol-phosphate dehydratase/histidinol phosphatase lpp1199 217 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 54298372 Pathogen - hypothetical protein lpp2436 1 None None None 54297157 Common hisG ATP phosphoribosyltransferase lpp1202 207 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 54298446 Pathogen - hypothetical protein lpp2510 1 None None None 54297289 Common hutU urocanate hydratase lpp1334 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 54298497 Common - hypothetical protein lpp2561 81 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 54298294 Common cecB Chemiosmotic efflux system C protein B lpp2352 173 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 54298448 Common - hypothetical protein lpp2512 3 None None None 54296644 Pathogen sidA SidA protein, substrate of the Dot/Icm transport system lpp0675 1 None None None 54297393 Pathogen - hypothetical protein lpp1438 1 None None None 54298904 Common - hypothetical protein lpp2971 42 COG3165 COG3165, Uncharacterized protein conserved in bacteria Function unknown 54296837 Common icd isocitrate dehydrogenase lpp0878 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 54298654 Common - acetyl-CoA carboxylase lpp2718 236 COG0439 AccC, Biotin carboxylase Lipid metabolism 54298731 Common - hypothetical protein lpp2795 216 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 54298845 Common - hypothetical protein lpp2912 39 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 54296825 Common - hypothetical protein lpp0866 48 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 54296815 Common mip macrophage infectivity potentiator lpp0855 135 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 54297558 Common - hypothetical protein lpp1608 123 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54296944 Common etfA Electron transfer flavoprotein, alpha subunit lpp0985 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 54296290 Common - hypothetical protein lpp0319 67 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 54299007 Common - hypothetical protein lpp3074 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 54298340 Pathogen - hypothetical protein lpp2399 1 None None None 54298429 Common - hypothetical protein lpp2493 27 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 54297707 Common - hypothetical protein lpp1758 50 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 54296038 Common - hypothetical protein lpp0055 6 None None None 54298346 Common - hypothetical protein lpp2405 35 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 54298755 Common rbfA Ribosome-binding factor A lpp2819 135 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 54298401 Common - hypothetical protein lpp2465 4 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 54297131 Common pilR hypothetical protein lpp1176 226 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 54296743 Pathogen - hypothetical protein lpp0782 1 None None None 54296147 Common lvhB3 Legionella vir homologue protein lpp0170 6 COG3702 VirB3, Type IV secretory pathway, VirB3 components Intracellular trafficking and secretion 54296369 Common rpsS 30S ribosomal protein S19 lpp0398 242 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 54298412 Pathogen - hypothetical protein lpp2476 1 None None None 54297736 Common - hypothetical protein lpp1787 171 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 54298293 Common cecA Chemiosmotic efflux system protein A-like protein lpp2351 177 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 54298315 Pathogen - hypothetical protein lpp2374 1 None None None 54296151 Pathogen lvrD Legionella vir region protein lpp0174 1 None None None 54297762 Common - hypothetical protein lpp1813 14 None None None 54297012 Pathogen - hypothetical protein lpp1054 1 None None None 54296731 Common - hypothetical protein lpp0762 41 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 54296014 Common - hypothetical protein lpp0031 52 COG2234 Iap, Predicted aminopeptidases General function prediction only 54298933 Common - hypothetical protein lpp3000 91 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 54297296 Pathogen - hypothetical protein lpp1341 2 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 54298938 Common fumC fumarate hydratase lpp3005 214 COG0114 FumC, Fumarase Energy production and conversion 54297485 Common - hypothetical protein lpp1530 28 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 54298027 Common stuC sensor histidine kinase lpp2084 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 54298504 Common - hypothetical protein lpp2568 131 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 54297738 Pathogen - hypothetical protein lpp1789 1 None None None 54296385 Common secY preprotein translocase subunit SecY lpp0414 227 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 54296517 Common hflK protease subunit HflK lpp0548 213 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 54297496 Common - hypothetical protein lpp1541 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 54296221 Common - hypothetical protein lpp0247 38 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 54297208 Common - hypothetical protein lpp1253 2 None None None 54298809 Common - hypothetical protein lpp2874 200 COG0062 COG0062, Uncharacterized conserved protein Function unknown 54296043 Common - hypothetical protein lpp0060 126 COG0789 SoxR, Predicted transcriptional regulators Transcription 54296615 Common - hypothetical protein lpp0646 86 COG0398 COG0398, Uncharacterized conserved protein Function unknown 54296826 Common ppsA phosphoenolpyruvate synthase lpp0867 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 54298960 Common dcd deoxycytidine triphosphate deaminase lpp3027 151 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 54298607 Common murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alani ne ligase lpp2671 212 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 54296508 Common pssA hypothetical protein lpp0539 152 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 54297305 Common fabG 3-oxoacyl-[acyl-carrier protein] reductase (3-ketoacyl-acyl carrier protein reductase) lpp1350 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54297763 Pathogen - hypothetical protein lpp1814 1 None None None 54297874 Pathogen - hypothetical protein lpp1929 1 None None None 54297382 Common bioA adenosylmethionine-8-amino-7-oxononanoate aminotransferase lpp1427 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 54298347 Pathogen - hypothetical protein lpp2406 1 None None None 54296270 Common - hypothetical protein lpp0299 182 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 54298839 Common - hypothetical protein lpp2906 35 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 54297225 Common glnS glutaminyl-tRNA synthetase lpp1270 244 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 54297290 Common hutH hypothetical protein lpp1335 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 54296650 Common pilE type-IV pilin lpp0681 44 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 54296635 Common - hypothetical protein lpp0666 211 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 54296333 Common - hypothetical protein lpp0362 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 54297548 Common - hypothetical protein lpp1598 29 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 54298847 Common - hypothetical protein lpp2914 85 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 54298855 Common - hypothetical protein lpp2922 93 COG1565 COG1565, Uncharacterized conserved protein Function unknown 54296204 Common - hypothetical protein lpp0230 19 COG3009 COG3009, Uncharacterized protein conserved in bacteria Function unknown 54296264 Pathogen - hypothetical protein lpp0293 2 None None None 54297699 Common flhB flagellar biosynthesis protein FlhB lpp1750 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 54297934 Common - hypothetical protein lpp1989 188 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 54297105 Pathogen - hypothetical protein lpp1150 1 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 54297142 Common - hypothetical protein lpp1187 81 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 54296390 Common rpoA DNA-directed RNA polymerase subunit alpha lpp0419 217 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 54296581 Common - hypothetical protein lpp0612 144 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 54297247 Common fliD hypothetical protein lpp1292 100 COG1345 FliD, Flagellar capping protein Cell motility and secretion 54296514 Common - hypothetical protein lpp0545 176 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 54296454 Common edd phosphogluconate dehydratase lpp0485 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 54298877 Pathogen - hypothetical protein lpp2944 1 None None None 54298600 Common ftsQ Cell division protein FtsQ lpp2664 67 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 54296594 Common - hypothetical protein lpp0625 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 54298419 Pathogen - hypothetical protein lpp2483 1 None None None 54296091 Common - hypothetical protein lpp0109 6 None None None 54296760 Pathogen - hypothetical protein lpp0799 1 None None None 54296217 Pathogen - hypothetical protein lpp0243 1 None None None 54298056 Pathogen - hypothetical protein lpp2113 1 None None None 54297363 Common - hypothetical protein lpp1408 74 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54298139 Common upp hypothetical protein lpp2196 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 54297937 Common gmk guanylate kinase lpp1992 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 54296243 Common - hypothetical protein lpp0270 65 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 54298130 Common - hypothetical protein lpp2187 224 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54297681 Common aat leucyl/phenylalanyl-tRNA--protein transferase lpp1732 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 54298229 Pathogen - hypothetical protein lpp2287 3 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54297365 Common - hypothetical protein lpp1410 187 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54297942 Common proC hypothetical protein lpp1997 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 54298165 Pathogen - hypothetical protein lpp2222 1 None None None 54297088 Common cfa cyclopropane fatty acyl phospholipid synthase lpp1133 132 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 54297188 Common flgK flagellar hook-associated protein FlgK lpp1233 121 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 54298270 Common - F0F1 ATP synthase subunit beta lpp2328 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 54296540 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase lpp0571 167 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 54296549 Common - hypothetical protein lpp0580 117 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 54298359 Common - hypothetical protein lpp2421 35 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 54296123 Common - hypothetical protein lpp0142 173 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 54297722 Common - hypothetical protein lpp1773 69 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 54298841 Common - hypothetical protein lpp2908 177 COG1278 CspC, Cold shock proteins Transcription 54297056 Pathogen - hypothetical protein lpp1101 1 None None None 54298574 Common - hypothetical protein lpp2638 41 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 54298912 Common tynA tyramine oxidase lpp2979 22 COG3733 TynA, Cu2+-containing amine oxidase Secondary metabolites biosynthesis, transport, and catabolism 54298380 Pathogen - hypothetical protein lpp2444 1 None None None 54297433 Common - hypothetical protein lpp1478 22 None None None 54297216 Common FolD methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase lpp1261 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 54296141 Common - hypothetical protein lpp0163 9 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 54298549 Pathogen - hypothetical protein lpp2613 1 None None None 54297690 Common lysS hypothetical protein lpp1741 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 54297297 Pathogen - hypothetical protein lpp1342 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54297813 Pathogen - hypothetical protein lpp1864 1 None None None 54296527 Common argF Ornithine carbamoyltransferase lpp0558 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 54298545 Pathogen - hypothetical protein lpp2609 1 None None None 54298408 Pathogen lidE hypothetical protein lpp2472 1 None None None 54296613 Pathogen - hypothetical protein lpp0644 1 None None None 54297041 Common - hypothetical protein lpp1083 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 54298041 Common - hypothetical protein lpp2098 50 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 54296069 Common - hypothetical protein lpp0087 158 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 54296748 Common - hypothetical protein lpp0787 159 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 54296473 Pathogen - hypothetical protein lpp0504 1 None None None 54297326 Common - hypothetical protein lpp1371 75 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 54297004 Common - hypothetical protein lpp1045 190 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 54298298 Common copA1 hypothetical protein lpp2356 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 54298479 Common - hypothetical protein lpp2543 199 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 54296181 Pathogen - hypothetical protein lpp0205 1 None None None 54296769 Common - hypothetical protein lpp0808 23 COG3369 COG3369, Uncharacterized conserved protein Function unknown 54298860 Common thyA thymidylate synthase lpp2927 138 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 54296353 Common nusG transcription antitermination protein NusG lpp0382 214 COG0250 NusG, Transcription antiterminator Transcription 54297906 Pathogen - hypothetical protein lpp1961 3 COG3774 OCH1, Mannosyltransferase OCH1 and related enzymes Cell envelope biogenesis, outer membrane 54296448 Common - protoheme IX farnesyltransferase lpp0479 177 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 54297790 Pathogen - hypothetical protein lpp1841 1 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 54297576 Common - hypothetical protein lpp1627 19 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 54296231 Common - hypothetical protein lpp0257 30 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 54296933 Common - hypothetical protein lpp0974 146 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 54296322 Common - hypothetical protein lpp0351 160 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 54298008 Pathogen - hypothetical protein lpp2065 2 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 54298091 Common - hypothetical protein lpp2148 76 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 54296146 Common lvhB2 Legionella vir homologue protein lpp0169 4 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 54296896 Common pntB NAD(P) transhydrogenase subunit beta (Pyridine nucleotide transhydrogenase subunit beta) lpp0937 122 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 54296365 Common rplC 50S ribosomal protein L3 lpp0394 246 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 54296775 Common - hypothetical protein lpp0814 16 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 54296422 Common - hypothetical protein lpp0452 129 COG1704 LemA, Uncharacterized conserved protein Function unknown 54298988 Common atpA F0F1 ATP synthase subunit alpha lpp3055 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 54296880 Pathogen ccmD heme exporter protein CcmD lpp0921 1 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 54297822 Common - hypothetical protein lpp1874 53 COG2850 COG2850, Uncharacterized conserved protein Function unknown 54297844 Common - hypothetical protein lpp1896 188 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 54296134 Common gap glyceraldehyde 3-phosphate dehydrogenase lpp0153 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 54297918 Pathogen - hypothetical protein lpp1973 1 None None None 54296077 Pathogen - hypothetical protein lpp0095 1 None None None 54296963 Common era GTP-binding protein Era lpp1004 236 COG1159 Era, GTPase General function prediction only 54297978 Pathogen - hypothetical protein lpp2033 1 None None None 54297451 Common folK hypothetical protein lpp1496 194 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 54297881 Pathogen - hypothetical protein lpp1936 1 None None None 54296911 Common - hypothetical protein lpp0952 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 54296404 Pathogen - hypothetical protein lpp0433 1 None None None 54298062 Pathogen - hypothetical protein lpp2119 1 None None None 54296573 Common - hypothetical protein lpp0604 126 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 54298310 Common - hypothetical protein lpp2368 44 COG3439 COG3439, Uncharacterized conserved protein Function unknown 54298071 Common - hypothetical protein lpp2128 81 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 54296434 Common rimM hypothetical protein lpp0465 154 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 54297389 Common aspS aspartyl-tRNA synthetase lpp1434 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54297909 Pathogen - hypothetical protein lpp1964 2 None None None 54297703 Pathogen fliO Flagellar protein fliO lpp1754 1 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 54297808 Pathogen - hypothetical protein lpp1859 3 None None None 54298188 Common - hypothetical protein lpp2246 13 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54297647 Common clcA chloride channel protein lpp1698 142 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 54297642 Pathogen - hypothetical protein lpp1693 2 None None None 54297474 Common - hypothetical protein lpp1519 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 54296754 Common nusB hypothetical protein lpp0793 158 COG0781 NusB, Transcription termination factor Transcription 54296108 Common - hypothetical protein lpp0127 54 COG3434 COG3434, Predicted signal transduction protein containing EAL and modified HD-GYP domains Signal transduction mechanisms 54298927 Common - hypothetical protein lpp2994 23 None None None 54297413 Common - hypothetical protein lpp1458 155 COG0456 RimI, Acetyltransferases General function prediction only 54298703 Common rplT 50S ribosomal protein L20 lpp2767 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 54296319 Common - hypothetical protein lpp0348 173 COG0583 LysR, Transcriptional regulator Transcription 54298614 Common carB carbamoyl-phosphate synthase large subunit lpp2678 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 54297355 Common scpA hypothetical protein lpp1400 137 COG1354 COG1354, Uncharacterized conserved protein Function unknown 54298304 Common cebB Chemiosmotic efflux system B protein B lpp2362 161 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 54298587 Common - hypothetical protein lpp2651 2 None None None 54298827 Common - hypothetical protein lpp2894 30 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 54296535 Common uppS Undecaprenyl pyrophosphate synthetase lpp0566 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 54297257 Common leuS leucyl-tRNA synthetase lpp1302 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54295994 Common - hypothetical protein lpp0011 114 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 54297771 Pathogen - hypothetical protein lpp1822 1 None None None 54296719 Common - hypothetical protein lpp0750 45 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 54297588 Common - hypothetical protein lpp1639 3 None None None 54297952 Common dnaK Chaperone protein DnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70) lpp2007 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 54298714 Common - hypothetical protein lpp2778 36 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 54297526 Common proA gamma-glutamyl phosphate reductase lpp1574 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 54297834 Common gltX Glutamyl-tRNA synthetase, catalytic subunit lpp1886 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 54297175 Common - hypothetical protein lpp1220 11 None None None 54297316 Common - hypothetical protein lpp1361 152 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 54298067 Pathogen - hypothetical protein lpp2124 1 None None None 54297446 Common hemL hypothetical protein lpp1491 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 54298357 Common - hypothetical protein lpp2419 20 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 54297632 Pathogen - hypothetical protein lpp1683 1 COG2940 COG2940, Proteins containing SET domain General function prediction only 54298562 Common - hypothetical protein lpp2626 82 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 54298101 Common - hypothetical protein lpp2158 25 None None None 54297445 Common - hypothetical protein lpp1490 77 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 54297855 Common - hypothetical protein lpp1910 55 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 54297982 Common - hypothetical protein lpp2037 65 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 54298754 Common truB tRNA pseudouridine synthase B lpp2818 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 54298426 Pathogen - hypothetical protein lpp2490 1 None None None 54298495 Common - hypothetical protein lpp2559 163 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 54296841 Common - hypothetical protein lpp0882 38 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54298350 Common - hypothetical protein lpp2409 11 None None None 54297550 Common - hypothetical protein lpp1600 221 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 54296524 Common - hypothetical protein lpp0555 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 54296809 Common accA acetyl-CoA carboxylase carboxyl transferase subunit alpha lpp0849 213 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 54297654 Pathogen - hypothetical protein lpp1705 1 None None None 54298469 Common - hypothetical protein lpp2533 46 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 54298771 Common nuoB NADH dehydrogenase subunit B lpp2835 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 54298450 Common - hypothetical protein lpp2514 32 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 54298975 Common - hypothetical protein lpp3042 116 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 54296446 Common - hypothetical protein lpp0477 10 None None None 54296163 Common - hypothetical protein lpp0186 6 None None None 54296697 Common - acetoacetate decarboxylase lpp0728 20 COG4689 Adc, Acetoacetate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 54298109 Pathogen - hypothetical protein lpp2166 1 None None None 54296679 Common - hypothetical protein lpp0710 33 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 54297166 Common - hypothetical protein lpp1211 120 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 54298257 Common - hypothetical protein lpp2315 60 COG0456 RimI, Acetyltransferases General function prediction only 54297314 Common - hypothetical protein lpp1359 180 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 54298016 Common ceaA Chemiosmotic efflux system protein A-like protein lpp2073 177 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 54296296 Common - hypothetical protein lpp0325 104 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54298752 Common pnp polynucleotide phosphorylase/polyadenylase lpp2816 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 54298652 Common panC hypothetical protein lpp2716 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 54298306 Common ctpA hypothetical protein lpp2364 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 54296165 Common - hypothetical protein lpp0188 110 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 54296587 Common - hypothetical protein lpp0618 64 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 54296310 Common - hypothetical protein lpp0339 119 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 54297910 Common - hypothetical protein lpp1965 38 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 54298596 Common - hypothetical protein lpp2660 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 54297152 Common hisA phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase lpp1197 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 54296623 Common - hypothetical protein lpp0654 173 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 54298417 Common ampC beta-lactamase lpp2481 136 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 54298576 Common - hypothetical protein lpp2640 21 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 54298689 Common - hypothetical protein lpp2753 178 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 54296977 Common - hypothetical protein lpp1018 2 None None None 54298140 Pathogen - hypothetical protein lpp2197 1 None None None 54298645 Common ispB hypothetical protein lpp2709 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 54298902 Common - hypothetical protein lpp2969 23 None None None 54298946 Common - hypothetical protein lpp3013 76 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 54298834 Common - hypothetical protein lpp2901 199 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 54298950 Pathogen - hypothetical protein lpp3017 1 None None None 54296115 Pathogen - hypothetical protein lpp0134 2 None None None 54297591 Pathogen - hypothetical protein lpp1642 1 None None None 54297263 Pathogen - hypothetical protein lpp1308 1 None None None 54296984 Pathogen - hypothetical protein lpp1025 1 None None None 54298741 Common - hypothetical protein lpp2805 24 None None None 54298195 Common - hypothetical protein lpp2253 103 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 54296377 Common rplE 50S ribosomal protein L5 lpp0406 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 54298088 Common - hypothetical protein lpp2145 101 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 54296036 Common - hypothetical protein lpp0053 35 COG2323 COG2323, Predicted membrane protein Function unknown 54296951 Common pilP Tfp pilus assembly protein PilP lpp0992 37 COG3168 PilP, Tfp pilus assembly protein PilP Cell motility and secretion / Intracellular trafficking and secretion 54296800 Common - hypothetical protein lpp0840 86 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 54296370 Common rplV 50S ribosomal protein L22 lpp0399 224 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 54296737 Common - hypothetical protein lpp0768 42 COG1297 COG1297, Predicted membrane protein Function unknown 54298424 Common - hypothetical protein lpp2488 2 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 54297856 Pathogen - hypothetical protein lpp1911 1 None None None 54297086 Common ladC adenylate cyclase lpp1131 93 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 54296999 Common - hypothetical protein lpp1040 182 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 54296418 Common - hypothetical protein lpp0448 6 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 54296900 Pathogen - hypothetical protein lpp0941 1 None None None 54297333 Common - hypothetical protein lpp1378 68 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 54297134 Common - hypothetical protein lpp1179 128 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 54297439 Pathogen - hypothetical protein lpp1484 1 None None None 54297821 Common - hypothetical protein lpp1873 83 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 54296186 Pathogen - hypothetical protein lpp0212 1 None None None 54298669 Common - hypothetical protein lpp2733 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 54298211 Common sdaC hypothetical protein lpp2269 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 54298869 Pathogen - hypothetical protein lpp2936 2 None None None 54296828 Common nadC nicotinate-nucleotide pyrophosphorylase lpp0869 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 54298460 Common shkA hypothetical protein lpp2524 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 54298941 Common - hypothetical protein lpp3008 4 None None None 54297605 Pathogen - hypothetical protein lpp1656 1 None None None 54297037 Pathogen - hypothetical protein lpp1079 1 None None None 54297219 Common - hypothetical protein lpp1264 25 COG5528 COG5528, Predicted integral membrane protein Function unknown 54297501 Pathogen - hypothetical protein lpp1546 1 None None None 54296302 Common - hypothetical protein lpp0331 37 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54297994 Common - hypothetical protein lpp2051 38 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54298459 Common - hypothetical protein lpp2523 142 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 54298557 Common - hypothetical protein lpp2621 18 COG2510 COG2510, Predicted membrane protein Function unknown 54298812 Common recN DNA repair protein recN lpp2877 206 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 54298355 Pathogen - hypothetical protein lpp2417 1 None None None 54297468 Common - hypothetical protein lpp1513 119 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 54297877 Common ralF RalF protein, translocated into host cells by the Dot/Icm system lpp1932 2 COG5307 COG5307, SEC7 domain proteins General function prediction only 54297887 Pathogen - hypothetical protein lpp1942 1 None None None 54296625 Common - hypothetical protein lpp0656 167 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 54296948 Common pilM Tfp pilus assembly protein, ATPase PilM lpp0989 82 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 54297458 Common - hypothetical protein lpp1503 77 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 54297895 Common - hypothetical protein lpp1950 20 None None None 54297374 Common secA preprotein translocase subunit SecA lpp1419 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 54297137 Common ribA Riboflavin biosynthesis protein RibA lpp1182 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 54296413 Common sdhA SdhA, substrate of the Dot/Icm system lpp0443 3 None None None 54297280 Common lpxB hypothetical protein lpp1325 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 54296756 Common pgpA Phosphatidylglycerophosphatase A lpp0795 105 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 54298202 Pathogen - hypothetical protein lpp2260 1 None None None 54296823 Common - hypothetical protein lpp0864 162 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 54298206 Common - 3-hydroxybutyrate dehydrogenase lpp2264 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54296990 Pathogen - hypothetical protein lpp1031 1 None None None 54297472 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 lpp1517 196 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 54296543 Common - hypothetical protein lpp0574 48 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 54297020 Common - hypothetical protein lpp1062 21 None None None 54297044 Pathogen - hypothetical protein lpp1086 1 None None None 54298553 Common - hypothetical protein lpp2617 87 COG2962 RarD, Predicted permeases General function prediction only 54298682 Pathogen - hypothetical protein lpp2746 1 None None None 54296062 Pathogen - hypothetical protein lpp0080 1 None None None 54296565 Common sdhB succinate dehydrogenase iron-sulfur subunit lpp0596 205 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 54296441 Common - hypothetical protein lpp0472 73 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 54296555 Common - hypothetical protein lpp0586 23 COG3153 COG3153, Predicted acetyltransferase General function prediction only 54296120 Common - GTPase EngB lpp0139 179 COG0218 COG0218, Predicted GTPase General function prediction only 54298732 Common - hypothetical protein lpp2796 66 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 54297637 Common guaB hypothetical protein lpp1688 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 54296129 Common - hypothetical protein lpp0148 24 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 54297479 Common thiS hypothetical protein lpp1524 4 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 54296579 Common - hypothetical protein lpp0610 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 54297991 Common - hypothetical protein lpp2047 2 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 54299001 Common - hypothetical protein lpp3068 26 None None None 54296929 Common flgA flagellar basal body P-ring biosynthesis protein FlgA lpp0970 63 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 54296228 Pathogen - hypothetical protein lpp0254 1 None None None 54297302 Common plsX fatty acid/phospholipid synthesis protein lpp1347 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 54296216 Common - hypothetical protein lpp0242 33 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 54296477 Pathogen icmS hypothetical protein lpp0508 2 None None None 54296433 Common trmD hypothetical protein lpp0464 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 54297237 Common - hypothetical protein lpp1282 4 None None None 54298525 Pathogen - hypothetical protein lpp2589 1 None None None 54297860 Common - hypothetical protein lpp1915 58 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 54297068 Common - hypothetical protein lpp1113 6 None None None 54297678 Common - hypothetical protein lpp1729 91 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 54296862 Common - hypothetical protein lpp0903 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 54297429 Common lssD Legionella secretion system protein D lpp1474 142 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 54296701 Common - hypothetical protein lpp0732 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 54298601 Common ddlA D-alanine--D-alanine ligase A lpp2665 215 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 54297560 Common - hypothetical protein lpp1610 75 COG2119 COG2119, Predicted membrane protein Function unknown 54296660 Common - hypothetical protein lpp0691 184 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 54297670 Common fliI flagellum-specific ATP synthase FliI lpp1721 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 54298531 Common aroF phospho-2-dehydro-3-heoxyheptonate aldolase lpp2595 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 54297261 Common - hypothetical protein lpp1306 163 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 54297928 Common - hypothetical protein lpp1983 173 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 54298795 Common - hypothetical protein lpp2859 176 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 54296685 Common - hypothetical protein lpp0716 14 None None None 54296175 Common - hypothetical protein lpp0198 35 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 54298239 Common sodC Superoxide dismutase [Cu-Zn] precursor lpp2297 84 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 54298170 Common ugpB hypothetical protein lpp2227 78 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 54297921 Pathogen - hypothetical protein lpp1976 1 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 54298896 Common - hypothetical protein lpp2963 74 COG3245 CycB, Cytochrome c5 Energy production and conversion 54298783 Common - hypothetical protein lpp2847 189 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 54297720 Common hemB delta-aminolevulinic acid dehydratase lpp1771 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 54296491 Common icmB/dotO hypothetical protein lpp0522 10 None None None 54297788 Common - hypothetical protein lpp1839 13 COG3297 PulL, Type II secretory pathway, component PulL Intracellular trafficking and secretion 54296941 Pathogen - hypothetical protein lpp0982 1 None None None 54297557 Common - hypothetical protein lpp1607 70 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 54298058 Pathogen - hypothetical protein lpp2115 1 None None None 54298043 Common - hypothetical protein lpp2100 25 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 54298143 Pathogen - hypothetical protein lpp2200 1 None None None 54297564 Pathogen - hypothetical protein lpp1615 1 None None None 54298482 Pathogen sdbB SdbB protein (putative substrate of the Dot/Icm system) lpp2546 1 None None None 54298155 Pathogen - hypothetical protein lpp2212 1 None None None 54296136 Pathogen - hypothetical protein lpp0155 1 None None None 54296055 Common - hypothetical protein lpp0073 30 COG4679 COG4679, Phage-related protein Function unknown 54298035 Common sdeC SdeC protein, substrate of the Dot/Icm system lpp2092 9 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 54298342 Common - hypothetical protein lpp2401 15 None None None 54297751 Common - D,D-heptose 1,7-bisphosphate phosphatase lpp1802 131 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 54297782 Common - hypothetical protein lpp1833 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 54297869 Common - hypothetical protein lpp1924 5 None None None 54296004 Common - hypothetical protein lpp0021 62 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 54297344 Common xapA purine nucleoside phosphorylase lpp1389 167 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 54298398 Common - hypothetical protein lpp2462 61 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 54297061 Common - hypothetical protein lpp1106 36 COG4325 COG4325, Predicted membrane protein Function unknown 54298386 Common - hypothetical protein lpp2450 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 54297524 Common - hypothetical protein lpp1572 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 54296874 Common fleQ transcriptional regulator FleQ lpp0915 172 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 54298764 Common nuoI NADH dehydrogenase subunit I lpp2828 188 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 54298676 Common dotA defect in organelle trafficking protein DotA lpp2740 12 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 54298438 Pathogen - hypothetical protein lpp2502 1 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 54296830 Common - hypothetical protein lpp0871 116 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 54297519 Common - hypothetical protein lpp1567 2 COG5238 RNA1, Ran GTPase-activating protein (RanGAP) involved in mRNA processing and transport Signal transduction mechanisms / RNA processing and modification 54298724 Common - hypothetical protein lpp2788 16 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 54296494 Common dotU hypothetical protein lpp0525 31 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 54297077 Pathogen - hypothetical protein lpp1122 1 None None None 54298936 Common trxA hypothetical protein lpp3003 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 54298962 Common - hypothetical protein lpp3029 74 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 54296855 Common trpD anthranilate phosphoribosyltransferase lpp0896 222 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 54298931 Common - hypothetical protein lpp2998 36 COG3785 COG3785, Uncharacterized conserved protein Function unknown 54297727 Common oxyR Hydrogen peroxide-inducible genes activator lpp1778 193 COG0583 LysR, Transcriptional regulator Transcription 54298644 Common - hypothetical protein lpp2708 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 54297503 Common - hypothetical protein lpp1548 10 None None None 54297666 Common mpl hypothetical protein lpp1717 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 54297229 Common lspE type II protein secretion ATPase LspE lpp1274 216 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 54296028 Common - hypothetical protein lpp0045 76 COG3000 ERG3, Sterol desaturase Lipid metabolism 54298627 Pathogen - hypothetical protein lpp2691 1 None None None 54298410 Pathogen - hypothetical protein lpp2474 1 None None None 54298182 Common - hypothetical protein lpp2239 172 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 54297103 Common - hypothetical protein lpp1148 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 54296020 Pathogen - hypothetical protein lpp0037 1 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 54297767 Pathogen - hypothetical protein lpp1818 1 None None None 54296242 Pathogen - hypothetical protein lpp0269 1 None None None 54298245 Common hemN hypothetical protein lpp2303 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 54296472 Pathogen - hypothetical protein lpp0503 1 None None None 54297510 Common - acetyl-CoA acetyltransferase lpp1555 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 54297628 Common rpsB 30S ribosomal protein S2 lpp1679 225 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 54297754 Common - hypothetical protein lpp1805 106 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 54296630 Common - hypothetical protein lpp0661 130 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 54296416 Common - hypothetical protein lpp0446 52 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 54298634 Common uvrC hypothetical protein lpp2698 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 54296762 Common - hypothetical protein lpp0801 144 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 54296858 Common - hypothetical protein lpp0899 33 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 54297207 Pathogen - hypothetical protein lpp1252 1 None None None 54297240 Common htrA periplasmic serine protease Do; heat shock protein HtrA lpp1285 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 54296258 Common - hypothetical protein lpp0285 10 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54298992 Common atpB F0F1 ATP synthase subunit A lpp3059 202 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 54298151 Common - hypothetical protein lpp2208 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 54298778 Common ftsH Cell division protease ftsH lpp2842 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 54296280 Common gabT hypothetical protein lpp0309 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 54296592 Pathogen - hypothetical protein lpp0623 1 None None None 54297971 Common pal Peptidoglycan-associated lipoprotein precursor (19 kDa surface antigen) (PPL) lpp2026 150 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 54297321 Common adk adenylate kinase lpp1366 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 54297724 Common - hypothetical protein lpp1775 229 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 54298716 Common - hypothetical protein lpp2780 45 COG0640 ArsR, Predicted transcriptional regulators Transcription 54296317 Common - hypothetical protein lpp0346 21 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 54298330 Common - hypothetical protein lpp2389 22 None None None 54298543 Pathogen - hypothetical protein lpp2607 1 None None None 54296694 Common - hypothetical protein lpp0725 26 COG5572 COG5572, Predicted integral membrane protein Function unknown 54298227 Common hemK hypothetical protein lpp2285 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 54298235 Pathogen - hypothetical protein lpp2293 1 None None None 54298283 Common - hypothetical protein lpp2341 43 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 54298275 Common - hypothetical protein lpp2333 29 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 54298698 Common rplM 50S ribosomal protein L13 lpp2762 233 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 54296156 Common lvhB11 Legionella vir homologue protein lpp0179 216 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 54297815 Common - hypothetical protein lpp1866 195 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 54296720 Pathogen - hypothetical protein lpp0751 1 None None None 54297634 Common glnD hypothetical protein lpp1685 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 54297940 Common - hypothetical protein lpp1995 218 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 54297604 Common - hypothetical protein lpp1655 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 54298986 Common atpD F0F1 ATP synthase subunit beta lpp3053 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 54297801 Common - hypothetical protein lpp1852 38 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54297948 Common sahH S-adenosyl-L-homocysteine hydrolase lpp2003 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 54297611 Common - hypothetical protein lpp1662 25 None None None 54296617 Pathogen - hypothetical protein lpp0648 1 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 54298325 Pathogen - hypothetical protein lpp2384 1 None None None 54297512 Pathogen - hypothetical protein lpp1557 1 None None None 54297811 Pathogen - hypothetical protein lpp1862 1 None None None 54296098 Common - hypothetical protein lpp0117 22 COG0456 RimI, Acetyltransferases General function prediction only 54298893 Common ctaG cytochrome C oxidase assembly protein lpp2960 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 54296729 Common - hypothetical protein lpp0760 67 COG2391 COG2391, Predicted transporter component General function prediction only 54297664 Pathogen - hypothetical protein lpp1715 1 None None None 54297697 Common flhF flagellar biosynthesis regulator FlhF lpp1748 231 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 54298910 Common - bifunctional methionine sulfoxide reductase B/A protein lpp2977 206 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 54298807 Common - hypothetical protein lpp2872 7 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 54298506 Common - hypothetical protein lpp2570 162 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54297402 Pathogen - hypothetical protein lpp1447 2 None None None 54296196 Common - hypothetical protein lpp0222 24 None None None 54296778 Common neuA CMP-N-acetlyneuraminic acid synthetase lpp0817 92 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 54297916 Pathogen - hypothetical protein lpp1971 1 None None None 54297227 Common - hypothetical protein lpp1272 81 COG3083 COG3083, Predicted hydrolase of alkaline phosphatase superfamily General function prediction only 54298414 Common - hypothetical protein lpp2478 17 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 54296033 Common - hypothetical protein lpp0050 128 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 54297792 Common - hypothetical protein lpp1843 35 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54298181 Common - hypothetical protein lpp2238 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 54298743 Pathogen - hypothetical protein lpp2807 1 None None None 54297328 Common serC phosphoserine aminotransferase lpp1373 122 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 54298376 Pathogen - hypothetical protein lpp2440 1 None None None 54296272 Common - hypothetical protein lpp0301 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 54297307 Common fabF 3-oxoacyl-[acyl-carrier-protein] synthase II (Beta-ketoacyl-ACP synthase II) lpp1352 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54296399 Common - hypothetical protein lpp0428 111 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 54297498 Pathogen - hypothetical protein lpp1543 2 None None None 54298349 Common - hypothetical protein lpp2408 20 COG2253 COG2253, Uncharacterized conserved protein Function unknown 54298954 Pathogen - hypothetical protein lpp3021 1 None None None 54296148 Common lvhB4 Legionella vir homologue protein lpp0171 59 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 54297731 Common msbA Lipid A export ATP-binding/permease protein MsbA lpp1782 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 54296375 Common rplN 50S ribosomal protein L14 lpp0404 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 54296012 Common - hypothetical protein lpp0029 196 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 54297483 Common - hypothetical protein lpp1528 20 None None None 54297074 Common - hypothetical protein lpp1119 132 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 54296383 Common rpmD 50S ribosomal protein L30 lpp0412 111 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 54296502 Common - hypothetical protein lpp0533 137 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54298179 Common asnC asparaginyl-tRNA synthetase lpp2236 231 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 54296791 Pathogen - hypothetical protein lpp0831 1 None None None 54298192 Common asd Aspartate-semialdehyde dehydrogenase lpp2250 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 54296985 Common - phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase lpp1026 61 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 54296266 Common cyoB cytochrome o ubiquinol oxidase subunit I lpp0295 171 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 54298405 Pathogen - hypothetical protein lpp2469 1 None None None 54298317 Common - hypothetical protein lpp2376 5 None None None 54297380 Common - hypothetical protein lpp1425 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 54297932 Common - hypothetical protein lpp1987 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 54296057 Common - hypothetical protein lpp0075 4 None None None 54297462 Common - hypothetical protein lpp1507 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 54296105 Common - hypothetical protein lpp0124 22 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 54297278 Common htpG heat shock protein 90 lpp1323 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 54296087 Pathogen - hypothetical protein lpp0105 2 None None None 54297014 Pathogen - hypothetical protein lpp1056 1 None None None 54296392 Common ssb Single-strand binding protein (SSB) (Helix-destabilizing protein) lpp0421 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 54296980 Common - hypothetical protein lpp1021 122 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 54298862 Common - hypothetical protein lpp2929 66 COG0730 COG0730, Predicted permeases General function prediction only 54297898 Common - hypothetical protein lpp1953 102 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 54296245 Common - hypothetical protein lpp0272 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 54297144 Common rdgC recombination associated protein lpp1189 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 54296522 Common - hypothetical protein lpp0553 186 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 54297452 Common - hypothetical protein lpp1497 78 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 54298260 Pathogen - hypothetical protein lpp2318 1 None None None 54297168 Common - hypothetical protein lpp1213 125 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 54296799 Pathogen - hypothetical protein lpp0839 1 None None None 54297656 Common - hypothetical protein lpp1707 66 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 54298578 Common - hypothetical protein lpp2642 109 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 54297361 Common - hypothetical protein lpp1406 131 COG1881 COG1881, Phospholipid-binding protein General function prediction only 54298585 Common - hypothetical protein lpp2649 46 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 54296848 Common - hypothetical protein lpp0889 131 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54297035 Common - hypothetical protein lpp1077 3 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 54298176 Common - hypothetical protein lpp2233 83 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 54298708 Common - hypothetical protein lpp2772 53 COG1872 COG1872, Uncharacterized conserved protein Function unknown 54297546 Common - hypothetical protein lpp1596 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 54297129 Common lidL hypothetical protein lpp1174 122 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 54297054 Common - hypothetical protein lpp1096 47 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 54296533 Pathogen - hypothetical protein lpp0564 1 None None None 54297259 Common - hypothetical protein lpp1304 31 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 54298365 Pathogen - hypothetical protein lpp2428 1 None None None 54298857 Common priA Primosomal protein N' (replication factor Y) lpp2924 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 54296345 Common - hypothetical protein lpp0374 90 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 54297096 Common potC hypothetical protein lpp1141 134 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 54298858 Common - hypothetical protein lpp2925 77 COG0824 FcbC, Predicted thioesterase General function prediction only 54296329 Common - hypothetical protein lpp0358 58 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 54297090 Common - hypothetical protein lpp1135 124 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 54297980 Common - hypothetical protein lpp2035 56 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 54296519 Common purA Adenylosuccinate synthetase (IMP--aspartate ligase) (AdSS) (AMPSase) lpp0550 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 54296360 Common rpsL 30S ribosomal protein S12 lpp0389 245 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 54297448 Common - hypothetical protein lpp1493 89 COG1981 COG1981, Predicted membrane protein Function unknown 54298701 Common pheT Phenylalanyl-tRNA synthetase, beta subunit lpp2765 246 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 54297586 Pathogen - hypothetical protein lpp1637 1 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 54298107 Pathogen - hypothetical protein lpp2164 1 None None None 54298452 Common - hypothetical protein lpp2516 33 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 54296007 Pathogen hbp hemin binding protein lpp0024 1 None None None 54297989 Common - hypothetical protein lpp2045 62 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 54297760 Common - hypothetical protein lpp1811 27 None None None 54296279 Common - hypothetical protein lpp0308 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 54297784 Common - hypothetical protein lpp1835 10 None None None 54298726 Common - hypothetical protein lpp2790 163 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 54297705 Common fliM Flagellar motor switch protein FliM lpp1756 111 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 54296711 Common groES co-chaperonin GroES lpp0742 214 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 54298780 Common - hypothetical protein lpp2844 99 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 54297528 Common - hypothetical protein lpp1576 35 COG0456 RimI, Acetyltransferases General function prediction only 54297639 Common minE Septum formation topological specificity factor lpp1690 84 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 54298267 Common - hypothetical protein lpp2325 18 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 54296966 Common - hypothetical protein lpp1007 17 None None None 54298973 Common argD acetylornithine aminotransferase lpp3040 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 54297214 Common - hypothetical protein lpp1259 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 54298233 Common plaA lysophospholipase A lpp2291 45 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 54298843 Common - hypothetical protein lpp2910 215 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 54297260 Common - hypothetical protein lpp1305 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 54297649 Common gatC Glutamyl-tRNA(Gln) amidotransferase (subunit C) lpp1700 56 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 54296106 Common - hypothetical protein lpp0125 15 None None None 54296777 Common hisH imidazole glycerol phosphate synthase subunit HisH lpp0816 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 54296695 Common - hypothetical protein lpp0726 42 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 54298793 Common - hypothetical protein lpp2857 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 54296637 Common - hypothetical protein lpp0668 68 COG2170 COG2170, Uncharacterized conserved protein Function unknown 54296707 Common - hypothetical protein lpp0738 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 54298149 Common - hypothetical protein lpp2206 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 54296320 Pathogen sdbA SdbA protein, putative substrate of the Dot/Icm system lpp0349 1 None None None 54296607 Common pyrB aspartate carbamoyltransferase catalytic subunit lpp0638 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 54297644 Common - hypothetical protein lpp1695 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 54297900 Pathogen - hypothetical protein lpp1955 1 None None None 54296287 Pathogen - hypothetical protein lpp0316 1 None None None 54296367 Common rplW 50S ribosomal protein L23 lpp0396 107 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 54297842 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase lpp1894 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 54296358 Common rpoB DNA-directed RNA polymerase subunit beta lpp0387 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 54296657 Pathogen - hypothetical protein lpp0688 1 None None None 54296183 Common - hypothetical protein lpp0208 3 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 54296785 Common rmlB dTDP-D-glucose 4,6-dehydratase lpp0824 233 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 54296351 Common tufA elongation factor Tu lpp0380 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 54296621 Common - cysteine desulfurase activator complex subunit SufB lpp0652 185 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 54298337 Pathogen - hypothetical protein lpp2396 1 None None None 54297093 Pathogen - hypothetical protein lpp1138 1 None None None 54298049 Common - hypothetical protein lpp2106 8 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 54296202 Common - hypothetical protein lpp0228 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 54298521 Common - hypothetical protein lpp2585 138 COG1522 Lrp, Transcriptional regulators Transcription 54297387 Common - hypothetical protein lpp1432 73 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 54297342 Common - hypothetical protein lpp1387 31 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 54296674 Common - hypothetical protein lpp0705 202 COG0281 SfcA, Malic enzyme Energy production and conversion 54297475 Pathogen - hypothetical protein lpp1520 1 None None None 54296898 Common pntA pyridine nucleotide transhydrogenase, alpha subunit lpp0939 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 54296251 Common - hypothetical protein lpp0278 11 None None None 54298037 Pathogen - hypothetical protein lpp2094 1 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 54298981 Pathogen - hypothetical protein lpp3048 1 None None None 54298392 Pathogen - hypothetical protein lpp2456 1 None None None 54298662 Common - hypothetical protein lpp2726 177 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 54298073 Common - hypothetical protein lpp2130 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 54297598 Common purM phosphoribosylaminoimidazole synthetase lpp1649 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 54298851 Pathogen - hypothetical protein lpp2918 1 None None None 54297537 Common - hypothetical protein lpp1587 10 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 54296481 Common icmO/dotL hypothetical protein lpp0512 17 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 54298006 Common - hypothetical protein lpp2063 32 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 54296575 Common - hypothetical protein lpp0606 86 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 54298466 Common - hypothetical protein lpp2530 38 COG3555 COG3555, Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases Posttranslational modification, protein turnover, chaperones 54298918 Pathogen - hypothetical protein lpp2985 1 None None None 54297430 Common lssE hypothetical protein lpp1475 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 54296600 Common add adenosine deaminase lpp0631 113 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 54296397 Common - hypothetical protein lpp0426 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54299006 Common trmE tRNA modification GTPase TrmE lpp3073 227 COG0486 ThdF, Predicted GTPase General function prediction only 54296970 Common - hypothetical protein lpp1011 127 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 54296411 Pathogen - hypothetical protein lpp0441 1 None None None 54298441 Common sflR hypothetical protein lpp2505 198 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54296810 Common - hypothetical protein lpp0850 219 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 54297688 Common rir2 ribonucleotide-diphosphate reductase subunit beta lpp1739 157 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 54297203 Common hmgA homogentisate 1,2-dioxygenase lpp1248 47 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 54297398 Common - hypothetical protein lpp1443 7 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 54298559 Common - hypothetical protein lpp2623 129 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 54297441 Common prpD 2-methylcitrate dehydratase lpp1486 62 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 54296081 Common - hypothetical protein lpp0099 24 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 54297997 Pathogen - hypothetical protein lpp2054 1 None None None 54297372 Common recJ Single-stranded-DNA-specific exonuclease RecJ lpp1417 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 54297716 Common - hypothetical protein lpp1767 191 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 54298512 Pathogen - hypothetical protein lpp2576 1 None None None 54297889 Common - hypothetical protein lpp1944 38 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54296759 Common - hypothetical protein lpp0798 23 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 54298225 Common hemA glutamyl tRNA reductase lpp2283 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 54296127 Common dapB hypothetical protein lpp0146 212 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 54296667 Common - hypothetical protein lpp0698 95 COG1295 Rbn, Predicted membrane protein Function unknown 54297139 Common pyrG CTP synthetase lpp1184 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 54298711 Pathogen - hypothetical protein lpp2775 1 None None None 54296563 Common sdhD succinate dehydrogenase, hydrophobic membrane anchor protein lpp0594 54 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 54298200 Common murI hypothetical protein lpp2258 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 54298114 Common - hypothetical protein lpp2171 12 None None None 54296853 Common - hypothetical protein lpp0894 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 54297879 Common - hypothetical protein lpp1934 61 COG1409 Icc, Predicted phosphohydrolases General function prediction only 54298555 Pathogen - hypothetical protein lpp2619 2 None None None 54298493 Common - hypothetical protein lpp2557 166 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 54297951 Common dnaJ chaperone protein DnaJ (heat shock protein) lpp2006 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 54296750 Common - hypothetical protein lpp0789 4 None None None 54296309 Pathogen - hypothetical protein lpp0338 1 None None None 54296645 Common - hypothetical protein lpp0676 5 None None None 54298204 Common dapA dihydrodipicolinate synthase lpp2262 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 54297230 Common lspD type II protein secretion LspD lpp1275 128 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 54296871 Common - hypothetical protein lpp0912 201 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 54296726 Common tdh L-threonine 3-dehydrogenase lpp0757 206 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 54296300 Common - hypothetical protein lpp0329 7 None None None 54297972 Common - hypothetical protein lpp2027 7 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 54297423 Common - hypothetical protein lpp1468 37 COG2921 COG2921, Uncharacterized conserved protein Function unknown 54297042 Pathogen - hypothetical protein lpp1084 1 None None None 54296075 Common - hypothetical protein lpp0093 116 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 54296132 Common - hypothetical protein lpp0151 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 54296545 Common - hypothetical protein lpp0576 11 COG2320 GrpB, Uncharacterized conserved protein Function unknown 54298075 Common - hypothetical protein lpp2132 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 54296214 Common - hypothetical protein lpp0240 33 COG0439 AccC, Biotin carboxylase Lipid metabolism 54297969 Common - hypothetical protein lpp2024 167 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 54298718 Common - hypothetical protein lpp2782 134 COG2860 COG2860, Predicted membrane protein Function unknown 54298750 Common folE GTP cyclohydrolase I lpp2814 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 54298647 Common feoB ferrous iron transporter B lpp2711 168 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 54297965 Common eno enolase lpp2020 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 54298308 Pathogen - hypothetical protein lpp2366 1 None None None 54298029 Pathogen - hypothetical protein lpp2086 1 None None None 54298123 Common - hypothetical protein lpp2180 190 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 54298658 Common ftsX hypothetical protein lpp2722 106 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 54296267 Common cyoC Cytochrome o ubiquinol oxidase subunit III cyoC lpp0296 154 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 54298594 Common - hypothetical protein lpp2658 2 COG4278 COG4278, Uncharacterized conserved protein Function unknown 54296113 Common gcvT glycine cleavage system aminomethyltransferase T lpp0132 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 54297312 Common lidH hypothetical protein lpp1357 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 54297896 Pathogen - hypothetical protein lpp1951 1 None None None 54297802 Common - hypothetical protein lpp1853 115 COG1254 AcyP, Acylphosphatases Energy production and conversion 54297614 Common - hypothetical protein lpp1665 19 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 54298354 Pathogen - hypothetical protein lpp2414 1 None None None 54296979 Common lig DNA ligase lpp1020 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 54298014 Common - hypothetical protein lpp2071 184 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 54296294 Common - hypothetical protein lpp0323 88 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 54296570 Common pdxH hypothetical protein lpp0601 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 54298820 Pathogen - hypothetical protein lpp2887 1 COG5113 UFD2, Ubiquitin fusion degradation protein 2 Posttranslational modification, protein turnover, chaperones 54298113 Common - hypothetical protein lpp2170 66 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 54297118 Common - hypothetical protein lpp1163 73 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 54297492 Common - hypothetical protein lpp1537 65 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 54296804 Common - hypothetical protein lpp0844 211 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 54297158 Common - hypothetical protein lpp1203 21 COG4496 COG4496, Uncharacterized protein conserved in bacteria Function unknown 54296802 Common - hypothetical protein lpp0842 96 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 54297285 Pathogen - hypothetical protein lpp1330 2 None None None 54297072 Common - hypothetical protein lpp1117 22 COG3469 COG3469, Chitinase Carbohydrate transport and metabolism 54296675 Common - hypothetical protein lpp0706 173 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 54297066 Pathogen - hypothetical protein lpp1111 1 None None None 54298785 Pathogen - hypothetical protein lpp2849 2 None None None 54298650 Common - hypothetical protein lpp2714 77 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 54297136 Common ribE riboflavin synthase subunit alpha lpp1181 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 54298849 Common - hypothetical protein lpp2916 98 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 54296589 Common - hypothetical protein lpp0620 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54297191 Pathogen - hypothetical protein lpp1236 1 None None None 54297499 Pathogen - hypothetical protein lpp1544 1 None None None 54296188 Common - hypothetical protein lpp0214 57 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 54297151 Common hisF imidazole glycerol phosphate synthase subunit HisF lpp1196 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 54298952 Common - hypothetical protein lpp3019 27 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 54298948 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase lpp3015 180 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 54296953 Common aroK shikimate kinase I lpp0994 203 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 54296876 Common - predicted inner membrane peptidase lpp0917 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 54297746 Common - hypothetical protein lpp1797 112 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 54298814 Common - hypothetical protein lpp2879 164 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 54298384 Common - hypothetical protein lpp2448 105 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 54298331 Common - hypothetical protein lpp2390 21 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 54298762 Common nuoK NADH-quinone oxidoreductase chain K lpp2826 155 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 54298323 Common - hypothetical protein lpp2382 21 None None None 54298281 Common - hypothetical protein lpp2339 13 None None None 54298277 Common - hypothetical protein lpp2335 19 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 54298887 Pathogen - hypothetical protein lpp2954 1 None None None 54297505 Common rpsF 30S ribosomal protein S6 lpp1550 173 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 54296496 Common prmA Ribosomal protein L11 methyltransferase lpp0527 179 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 54296887 Common - hypothetical protein lpp0928 7 None None None 54297419 Common - hypothetical protein lpp1464 205 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 54297958 Common argS arginyl-tRNA synthetase lpp2013 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54296735 Common hutI hypothetical protein lpp0766 101 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 54296497 Common accC Biotin carboxylase (A subunit of acetyl-CoA carboxylase) lpp0528 222 COG0439 AccC, Biotin carboxylase Lipid metabolism 54297662 Common - hypothetical protein lpp1713 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 54296026 Common - hypothetical protein lpp0043 53 COG3781 COG3781, Predicted membrane protein Function unknown 54298688 Common mutL DNA mismatch repair protein MutL lpp2752 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 54298285 Pathogen - hypothetical protein lpp2343 1 None None None 54296632 Common - hypothetical protein lpp0663 202 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 54298964 Common - hypothetical protein lpp3031 3 None None None 54298674 Common - hypothetical protein lpp2738 6 None None None 54296869 Common - hypothetical protein lpp0910 95 COG0327 COG0327, Uncharacterized conserved protein Function unknown 54297756 Common - hypothetical protein lpp1807 104 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54296654 Common - hypothetical protein lpp0685 24 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 54297357 Common rluB hypothetical protein lpp1402 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 54298243 Common mdh malate dehydrogenase lpp2301 134 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 54298668 Common - hypothetical protein lpp2732 77 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 54298671 Common - hypothetical protein lpp2735 54 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 54296019 Common - hypothetical protein lpp0036 158 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 54296539 Common - hypothetical protein lpp0570 90 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 54296470 Common - hypothetical protein lpp0501 3 COG4278 COG4278, Uncharacterized conserved protein Function unknown 54298734 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase lpp2798 212 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 54298255 Pathogen - hypothetical protein lpp2313 1 COG0456 RimI, Acetyltransferases General function prediction only 54298836 Pathogen - hypothetical protein lpp2903 1 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 54296238 Common - hypothetical protein lpp0264 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54298760 Common nuoM NADH-quinone oxidoreductase chain M lpp2824 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 54298603 Common murC UDP-N-acetylmuramate--L-alanine ligase lpp2667 210 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 54296744 Common - hypothetical protein lpp0783 2 None None None 54299003 Pathogen - hypothetical protein lpp3070 2 None None None 54297729 Pathogen - hypothetical protein lpp1780 1 None None None 54298995 Common - hypothetical protein lpp3062 61 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 54298436 Pathogen - hypothetical protein lpp2500 1 None None None 54296225 Pathogen - hypothetical protein lpp0251 1 None None None 54297126 Common - hypothetical protein lpp1171 78 COG1355 COG1355, Predicted dioxygenase General function prediction only 54296064 Pathogen - hypothetical protein lpp0082 1 None None None 54296860 Common - hypothetical protein lpp0901 113 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 54298509 Pathogen - hypothetical protein lpp2573 1 None None None 54297469 Common pabB hypothetical protein lpp1514 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 54296557 Common - hypothetical protein lpp0588 25 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 54298527 Pathogen - hypothetical protein lpp2591 2 None None None 54297400 Pathogen - hypothetical protein lpp1445 1 None None None 54296687 Common - hypothetical protein lpp0718 189 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 54296431 Common - hypothetical protein lpp0462 208 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 54297672 Common fliG Flagellar motor switch protein lpp1723 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 54298636 Common phhA phenylalanine 4-monooxygenase lpp2700 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 54297391 Common mutH DNA mismatch repair protein lpp1436 30 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 54297437 Common - hypothetical protein lpp1482 27 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 54298045 Common - hypothetical protein lpp2102 4 None None None 54297562 Common thrC threonine synthase lpp1613 180 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 54296464 Common - hypothetical protein lpp0495 3 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 54296158 Common lvrE Legionella vir region protein lpp0181 5 None None None 54298564 Common - hypothetical protein lpp2628 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 54297578 Common - hypothetical protein lpp1629 64 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 54296916 Pathogen - hypothetical protein lpp0957 1 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 54297267 Common lspK type II secretory pathway protein lpp1312 34 COG3156 PulK, Type II secretory pathway, component PulK Intracellular trafficking and secretion 54298237 Common - hypothetical protein lpp2295 91 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 54296191 Pathogen - hypothetical protein lpp0217 1 None None None 54297271 Common lspG type II secretory pathway protein LspG lpp1316 106 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 54296920 Common - hypothetical protein lpp0961 5 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 54296892 Common - hypothetical protein lpp0933 165 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 54298745 Pathogen - hypothetical protein lpp2809 1 None None None 54296438 Common - hypothetical protein lpp0469 18 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 54298086 Common - hypothetical protein lpp2143 146 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 54296997 Common - hypothetical protein lpp1038 110 COG2135 COG2135, Uncharacterized conserved protein Function unknown 54298213 Common - hypothetical protein lpp2271 160 COG5008 PilU, Tfp pilus assembly protein, ATPase PilU Cell motility and secretion / Intracellular trafficking and secretion 54296198 Pathogen - hypothetical protein lpp0224 1 None None None 54298157 Common - hypothetical protein lpp2214 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 54297571 Common iolCB hypothetical protein lpp1622 163 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 54298894 Common coxA cytochrome c oxidase, subunit I lpp2961 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 54297335 Common pyrF orotidine 5`-phosphate decarboxylase lpp1380 171 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 54298520 Common smlA hypothetical protein lpp2584 136 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54296872 Common - hypothetical protein lpp0913 178 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 54298215 Common - hypothetical protein lpp2273 25 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 54297572 Common iolG hypothetical protein lpp1623 139 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 54296851 Common - hypothetical protein lpp0892 7 COG3319 COG3319, Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases Secondary metabolites biosynthesis, transport, and catabolism 54298901 Pathogen - hypothetical protein lpp2968 1 None None None 54298908 Pathogen - hypothetical protein lpp2975 1 None None None 54298898 Common - hypothetical protein lpp2965 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 54297742 Common - hypothetical protein lpp1793 155 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 54297673 Common fliF flagellar MS-ring protein lpp1724 128 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 54298039 Common sdeA hypothetical protein lpp2096 4 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 54297266 Common - hypothetical protein lpp1311 184 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 54297084 Common - hypothetical protein lpp1129 189 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 54297852 Pathogen - hypothetical protein lpp1904 1 None None None 54296192 Pathogen - hypothetical protein lpp0218 1 None None None 54296559 Pathogen lvgA hypothetical protein lpp0590 1 None None None 54297477 Common - hypothetical protein lpp1522 78 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 54297535 Common - hypothetical protein lpp1585 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 54298335 Common - hypothetical protein lpp2394 22 None None None 54297064 Pathogen - hypothetical protein lpp1109 1 None None None 54298299 Pathogen - hypothetical protein lpp2357 1 None None None 54296185 Pathogen - hypothetical protein lpp0211 2 None None None 54296705 Common - hypothetical protein lpp0736 29 COG2267 PldB, Lysophospholipase Lipid metabolism 54296996 Pathogen - hypothetical protein lpp1037 1 None None None 54298089 Common - hypothetical protein lpp2146 13 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 54298791 Common pepN aminopeptidase N lpp2855 158 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 54296212 Common - hypothetical protein lpp0238 95 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 54297135 Common ribD Riboflavin biosynthesis protein RibD lpp1180 205 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 54297283 Common rodA Rod shape-determining protein rodA lpp1328 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 54298080 Pathogen - hypothetical protein lpp2137 1 None None None 54298996 Common - hypothetical protein lpp3063 62 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 54297384 Common bioF 8-amino-7-oxononanoate synthase lpp1429 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 54298978 Pathogen - hypothetical protein lpp3045 1 None None None 54298127 Common - hypothetical protein lpp2184 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54296663 Common hslV ATP-dependent protease peptidase subunit lpp0694 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 54298624 Common - hypothetical protein lpp2688 190 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 54296967 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ lpp1008 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 54298883 Common parA hypothetical protein lpp2950 224 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 54297579 Common - hypothetical protein lpp1630 14 None None None 54297871 Common - hypothetical protein lpp1926 15 COG5212 PDE1, Low-affinity cAMP phosphodiesterase Signal transduction mechanisms 54298625 Common rpsT 30S ribosomal protein S20 lpp2689 210 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 54298371 Common - hypothetical protein lpp2435 83 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 54298232 Pathogen - hypothetical protein lpp2290 1 None None None 54297816 Pathogen - hypothetical protein lpp1868 1 None None None 54296510 Common - hypothetical protein lpp0541 122 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 54297569 Common iolE hypothetical protein lpp1620 67 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 54296315 Common pncB nicotinate phosphoribosyltransferase lpp0344 138 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 54298535 Common - tellurite resistance protein TehB lpp2599 30 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 54298434 Common - hypothetical protein lpp2498 71 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 54297313 Common anmK anhydro-N-acetylmuramic acid kinase lpp1358 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 54297454 Common - hypothetical protein lpp1499 126 COG1520 COG1520, FOG: WD40-like repeat Function unknown 54297407 Pathogen - hypothetical protein lpp1452 1 None None None 54297975 Common - hypothetical protein lpp2030 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 54297053 Pathogen - hypothetical protein lpp1095 1 None None None 54297127 Common - hypothetical protein lpp1172 109 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 54297336 Common - hypothetical protein lpp1381 51 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 54297758 Common - hypothetical protein lpp1809 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 54298491 Common lepB effector protein B, substrate of the Dot/Icm secretion system lpp2555 127 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54297507 Common - hypothetical protein lpp1552 3 None None None 54296489 Pathogen icmD hypothetical protein lpp0520 2 None None None 54298672 Pathogen - hypothetical protein lpp2736 2 None None None 54297193 Common - hypothetical protein lpp1238 135 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 54298923 Common - hypothetical protein lpp2990 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 54296023 Common - hypothetical protein lpp0040 5 None None None 54297235 Common - hypothetical protein lpp1280 50 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 54297755 Common uvrD DNA-dependent helicase II lpp1806 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 54295998 Common - hypothetical protein lpp0015 117 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 54298248 Common gcp hypothetical protein lpp2306 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 54297205 Common ruvC Crossover junction endodeoxyribonuclease ruvC lpp1250 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 54296971 Common - hypothetical protein lpp1012 203 COG0388 COG0388, Predicted amidohydrolase General function prediction only 54296588 Pathogen - hypothetical protein lpp0619 1 None None None 54298943 Common - hypothetical protein lpp3010 2 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54298610 Common - hypothetical protein lpp2674 9 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 54298566 Pathogen - hypothetical protein lpp2630 1 None None None 54297825 Common - hypothetical protein lpp1877 3 None None None 54296499 Common aroQ 3-dehydroquinate dehydratase lpp0530 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 54297521 Common - hypothetical protein lpp1569 27 None None None 54296861 Common kdsD hypothetical protein lpp0902 154 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 54297359 Pathogen - hypothetical protein lpp1404 1 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 54298595 Common - hypothetical protein lpp2659 59 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 54298199 Common gpsA hypothetical protein lpp2257 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 54298011 Pathogen - hypothetical protein lpp2068 1 None None None 54296722 Common - hypothetical protein lpp0753 157 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 54298153 Common - hypothetical protein lpp2210 128 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 54298393 Common - hypothetical protein lpp2457 123 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54296882 Common ccmF cytochrome C-type biogenesis protein CcmF lpp0923 122 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 54298363 Common - hypothetical protein lpp2426 7 COG1476 COG1476, Predicted transcriptional regulators Transcription 54296655 Common - hypothetical protein lpp0686 33 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 54296604 Common - hypothetical protein lpp0635 7 None None None 54296468 Pathogen - hypothetical protein lpp0499 1 COG1289 COG1289, Predicted membrane protein Function unknown 54296208 Pathogen - hypothetical protein lpp0234 1 None None None 54297162 Common - hypothetical protein lpp1207 179 COG1278 CspC, Cold shock proteins Transcription 54297470 Common - hypothetical protein lpp1515 157 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 54298144 Common - hypothetical protein lpp2201 131 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 54297890 Common - hypothetical protein lpp1945 14 None None None 54298389 Common - hypothetical protein lpp2453 118 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 54298769 Common nuoD NADH dehydrogenase subunit D lpp2833 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 54296178 Common - hypothetical protein lpp0202 5 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 54298971 Common grlA glutaredoxin-like protein lpp3038 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 54298095 Common - hypothetical protein lpp2152 42 COG1371 COG1371, Uncharacterized conserved protein Function unknown 54298891 Pathogen - hypothetical protein lpp2958 1 None None None 54298343 Common - hypothetical protein lpp2402 65 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 54298710 Pathogen - hypothetical protein lpp2774 1 None None None 54296634 Common - hypothetical protein lpp0665 13 None None None 54297783 Common rnc hypothetical protein lpp1834 216 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 54298250 Common lporfX hypothetical protein lpp2308 151 COG1610 COG1610, Uncharacterized conserved protein Function unknown 54297416 Common aceE pyruvate dehydrogenase subunit E1 lpp1461 138 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 54298241 Common - hypothetical protein lpp2299 224 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 54296176 Common - hypothetical protein lpp0199 62 None None None 54297684 Common pmbA hypothetical protein lpp1735 157 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 54298301 Common - thymidine phosphorylase lpp2359 133 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 54298696 Common petA hypothetical protein lpp2760 93 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 54296950 Common pilO Tfp pilus assembly protein PilO lpp0991 46 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 54298428 Pathogen - hypothetical protein lpp2492 1 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 54296583 Common dinP hypothetical protein lpp0614 184 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 54298078 Common - hypothetical protein lpp2135 21 None None None 54296943 Common etfB Electron transfer flavoprotein beta-subunit (Beta-ETF) lpp0984 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 54298180 Pathogen - hypothetical protein lpp2237 1 None None None 54297124 Common - nucleotide-binding protein lpp1169 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 54296253 Common - hypothetical protein lpp0280 40 COG3002 COG3002, Uncharacterized protein conserved in bacteria Function unknown 54296987 Common - hypothetical protein lpp1028 151 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 54298571 Common - hypothetical protein lpp2635 103 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 54297130 Common pilS hypothetical protein lpp1175 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 54298190 Common - hypothetical protein lpp2248 28 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 54296486 Common icmE/dotG hypothetical protein lpp0517 64 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 54296213 Common - hypothetical protein lpp0239 105 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54298831 Common smpB SsrA-binding protein lpp2898 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 54298403 Common - hypothetical protein lpp2467 92 COG0583 LysR, Transcriptional regulator Transcription 54296806 Common - hypothetical protein lpp0846 97 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 54297156 Common hisD histidinol dehydrogenase lpp1201 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 54298110 Common - hypothetical protein lpp2167 3 None None None 54296995 Pathogen - hypothetical protein lpp1036 2 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 54296199 Common - hypothetical protein lpp0225 121 COG0432 COG0432, Uncharacterized conserved protein Function unknown 54296903 Pathogen - hypothetical protein lpp0944 1 None None None 54297481 Common thiDE hypothetical protein lpp1526 228 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 54298119 Common - hypothetical protein lpp2176 10 None None None 54298873 Common - hypothetical protein lpp2940 134 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 54296641 Common tag hypothetical protein lpp0672 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 54296003 Common - hypothetical protein lpp0020 11 None None None 54296835 Common - hypothetical protein lpp0876 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 54297596 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase lpp1647 217 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 54297394 Common - hypothetical protein lpp1439 37 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 54297067 Pathogen - hypothetical protein lpp1112 1 None None None 54296085 Common - hypothetical protein lpp0103 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 54297927 Common secD preprotein translocase subunit SecD lpp1982 205 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 54296011 Common - hypothetical protein lpp0028 47 COG2941 CAT5, Ubiquinone biosynthesis protein COQ7 Coenzyme metabolism 54296955 Common - hypothetical protein lpp0996 11 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 54297914 Common - hypothetical protein lpp1969 62 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 54297115 Pathogen - hypothetical protein lpp1160 1 None None None 54296119 Common - hypothetical protein lpp0138 61 COG2863 COG2863, Cytochrome c553 Energy production and conversion 54298443 Common - hypothetical protein lpp2507 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 54296732 Pathogen - hypothetical protein lpp0763 2 None None None 54298967 Common - hypothetical protein lpp3034 143 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 54296668 Common rtxA-1 structural toxin protein RtxA lpp0699 93 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 54298052 Common - hypothetical protein lpp2109 25 COG5628 COG5628, Predicted acetyltransferase General function prediction only 54296560 Common - hypothetical protein lpp0591 2 None None None 54297323 Common glpD glycerol-3-phosphate dehydrogenase lpp1368 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 54296130 Common - hypothetical protein lpp0149 5 None None None 54298787 Common - hypothetical protein lpp2851 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 54297726 Common - hypothetical protein lpp1777 5 None None None 54298221 Common - hypothetical protein lpp2279 172 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 54299008 Common - hypothetical protein lpp3075 183 COG0759 COG0759, Uncharacterized conserved protein Function unknown 54298439 Pathogen - hypothetical protein lpp2503 4 None None None 54298454 Pathogen - hypothetical protein lpp2518 1 None None None 54296169 Pathogen - hypothetical protein lpp0192 1 None None None 54298121 Common - hypothetical protein lpp2178 157 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 54298844 Common - hypothetical protein lpp2911 34 None None None 54298655 Common - hypothetical protein lpp2719 81 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 54296110 Common - hypothetical protein lpp0129 38 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 54298917 Common - hypothetical protein lpp2984 14 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 54296306 Common - hypothetical protein lpp0335 8 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 54296682 Common - hypothetical protein lpp0713 165 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 54296368 Common rplB 50S ribosomal protein L2 lpp0397 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 54298551 Pathogen - hypothetical protein lpp2615 2 None None None 54298252 Common rpoD RNA polymerase sigma factor rpoD (Sigma-70) lpp2310 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 54296145 Common lvrC Legionella vir region protein lpp0168 33 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 54297049 Common - hypothetical protein lpp1091 103 COG3177 COG3177, Uncharacterized conserved protein Function unknown 54297961 Pathogen - hypothetical protein lpp2016 1 None None None 54298209 Common motB flagellar motor protein MotB lpp2267 110 COG1360 MotB, Flagellar motor protein Cell motility and secretion 54296403 Pathogen - hypothetical protein lpp0432 1 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 54297999 Common - hypothetical protein lpp2056 47 COG5421 COG5421, Transposase DNA replication, recombination, and repair 54296237 Common - hypothetical protein lpp0263 53 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 54296568 Common sucC succinyl-CoA synthetase, beta subunit lpp0599 207 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 54298168 Pathogen - hypothetical protein lpp2225 1 None None None 54296923 Common - hypothetical protein lpp0964 11 None None None 54297370 Common - aminotransferase lpp1415 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 54297866 Common - hypothetical protein lpp1921 219 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 54297883 Common - hypothetical protein lpp1938 143 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 54298158 Common pta bifunctional enoyl-CoA hydratase/phosphate acetyltransferase lpp2215 115 COG0280 Pta, Phosphotransacetylase Energy production and conversion 54298641 Common - 50S ribosomal protein L25/general stress protein Ctc lpp2705 192 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 54297779 Common tig trigger factor lpp1830 214 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 54296414 Common - hypothetical protein lpp0444 32 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 54297025 Pathogen - hypothetical protein lpp1067 1 None None None 54298135 Pathogen - hypothetical protein lpp2192 1 None None None 54296444 Common - hypothetical protein lpp0475 21 None None None 54297463 Pathogen - hypothetical protein lpp1508 1 None None None 54297379 Pathogen - hypothetical protein lpp1424 1 None None None 54296073 Common pepP hypothetical protein lpp0091 243 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 54298683 Common - hypothetical protein lpp2747 81 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 54298735 Common - hypothetical protein lpp2799 163 COG1162 COG1162, Predicted GTPases General function prediction only 54297404 Pathogen - hypothetical protein lpp1449 1 None None None 54296812 Pathogen - hypothetical protein lpp0852 1 None None None 54295988 Common - hypothetical protein lpp0005 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 54298003 Common - hypothetical protein lpp2060 182 COG0583 LysR, Transcriptional regulator Transcription 54297797 Common - hypothetical protein lpp1848 75 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54298956 Pathogen - hypothetical protein lpp3023 1 None None None 54297031 Common - hypothetical protein lpp1073 17 None None None 54296702 Pathogen - hypothetical protein lpp0733 1 None None None 54296335 Pathogen - hypothetical protein lpp0364 1 None None None 54296715 Common parE DNA topoisomerase IV subunit B lpp0746 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 54296537 Common ecfE hypothetical protein lpp0568 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 54298538 Common - hypothetical protein lpp2602 93 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 54296104 Pathogen - hypothetical protein lpp0123 1 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 54297032 Common - hypothetical protein lpp1074 4 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 54298465 Common - hypothetical protein lpp2529 194 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54298047 Pathogen - hypothetical protein lpp2104 1 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 54298161 Common - hypothetical protein lpp2218 22 None None None 54296763 Common - hypothetical protein lpp0802 34 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 54297443 Common - hypothetical protein lpp1488 120 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 54296408 Common - hypothetical protein lpp0437 53 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 54297007 Common - hypothetical protein lpp1048 19 None None None 54297652 Pathogen - hypothetical protein lpp1703 1 None None None 54297095 Common potD hypothetical protein lpp1140 136 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 54298475 Common hypF Hydrogenase maturation protein HypF lpp2539 112 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 54298352 Pathogen - hypothetical protein lpp2412 1 None None None 54296795 Pathogen - hypothetical protein lpp0835 1 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 54298339 Common - hypothetical protein lpp2398 35 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 54296779 Common neuB N-acetylneuraminic acid condensing enzyme lpp0818 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 54297700 Common fliR Flagellar biosynthetic protein fliR lpp1751 104 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 54298884 Common parB hypothetical protein lpp2951 187 COG1475 Spo0J, Predicted transcriptional regulators Transcription 54298723 Common - hypothetical protein lpp2787 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 54296223 Common - hypothetical protein lpp0249 114 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 54296918 Pathogen - hypothetical protein lpp0959 1 None None None 54296894 Common prfC peptide chain release factor 3 lpp0935 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 54297775 Common hubB hypothetical protein lpp1826 212 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 54298147 Common - hypothetical protein lpp2204 176 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 54296420 Pathogen - hypothetical protein lpp0450 1 None None None 54297836 Common pfp 6-phosphofructokinase lpp1888 154 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 54296677 Common dam DNA adenine methylase lpp0708 93 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 54296357 Common rplL 50S ribosomal protein L7/L12 lpp0386 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 54298878 Common - hypothetical protein lpp2945 177 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 54296045 Pathogen - hypothetical protein lpp0062 1 COG3428 COG3428, Predicted membrane protein Function unknown 54297851 Common - hypothetical protein lpp1903 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 54297902 Pathogen - hypothetical protein lpp1957 1 None None None 54297646 Common - hypothetical protein lpp1697 189 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 54297184 Common flgG flagellar basal body rod protein FlgG lpp1229 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 54295991 Pathogen - hypothetical protein lpp0008 1 None None None 54297967 Common - hypothetical protein lpp2022 32 COG1577 ERG12, Mevalonate kinase Lipid metabolism 54296171 Common - hypothetical protein lpp0194 96 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 54296350 Pathogen - hypothetical protein lpp0379 1 None None None 54297905 Common - hypothetical protein lpp1960 127 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 54298472 Common hypE Hydrogenase expression/formation protein HypE lpp2536 164 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 54298166 Common lidB hypothetical protein lpp2223 28 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 54297925 Common - hypothetical protein lpp1980 95 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 54297581 Common - hypothetical protein lpp1632 18 COG4299 COG4299, Uncharacterized protein conserved in bacteria Function unknown 54297140 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase lpp1185 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 54296341 Pathogen - hypothetical protein lpp0370 1 None None None 54297306 Common acp Acyl carrier protein (ACP) lpp1351 211 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54296059 Common - hypothetical protein lpp0077 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 54297177 Common - hypothetical protein lpp1222 89 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54297253 Common - hypothetical protein lpp1298 99 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 54296764 Common dnaB Replicative DNA helicase lpp0803 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 54296752 Common glyA hypothetical protein lpp0791 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 54298853 Pathogen - hypothetical protein lpp2920 1 None None None 54297789 Common - hypothetical protein lpp1840 11 COG3149 PulM, Type II secretory pathway, component PulM Intracellular trafficking and secretion 54296348 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase PdxA lpp0377 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 54296361 Common rpsG 30S ribosomal protein S7 lpp0390 216 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 54298561 Pathogen - hypothetical protein lpp2625 1 None None None 54296935 Pathogen - hypothetical protein lpp0976 1 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 54297848 Pathogen - hypothetical protein lpp1900 1 None None None 54297215 Pathogen - hypothetical protein lpp1260 1 None None None 54297554 Common - hypothetical protein lpp1604 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 54296972 Common tldD TldD protein lpp1013 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 54298666 Common dotB defect in organelle trafficking protein DotB (ATPase) lpp2730 198 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 54296652 Common - hypothetical protein lpp0683 10 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 54297585 Common - hypothetical protein lpp1636 80 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 54296429 Pathogen - hypothetical protein lpp0460 1 None None None 54296746 Common valS valyl-tRNA synthetase lpp0785 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54298383 Pathogen - hypothetical protein lpp2447 1 None None None 54296291 Common rhlE hypothetical protein lpp0320 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 54297098 Common potA putrescine/spermidine ABC transporter ATPase protein lpp1143 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 54296326 Common - hypothetical protein lpp0355 191 COG0583 LysR, Transcriptional regulator Transcription 54298104 Common - hypothetical protein lpp2161 2 None None None 54298864 Common - dinucleoside polyphosphate hydrolase lpp2931 111 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 54297523 Common - hypothetical protein lpp1571 21 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 54298568 Common gcdH hypothetical protein lpp2632 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 54298871 Pathogen - hypothetical protein lpp2938 1 None None None 54296770 Common - hypothetical protein lpp0809 182 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 54298609 Common smc hypothetical protein lpp2673 186 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54298064 Pathogen - hypothetical protein lpp2121 1 None None None 54297826 Pathogen - hypothetical protein lpp1878 2 None None None 54298582 Common - hypothetical protein lpp2646 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 54296789 Common wecA alpha-N-acetylglucosaminyltransferase lpp0828 194 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 54297396 Pathogen - hypothetical protein lpp1441 2 None None None 54296521 Common - hypothetical protein lpp0552 59 COG1438 ArgR, Arginine repressor Transcription 54296246 Common - hypothetical protein lpp0273 9 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 54298985 Common atpC F0F1 ATP synthase subunit epsilon lpp3052 146 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 54296001 Common - hypothetical protein lpp0018 108 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54296845 Common - hypothetical protein lpp0886 30 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 54296838 Common - hypothetical protein lpp0879 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 54296693 Common - hypothetical protein lpp0724 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 54297957 Common - hypothetical protein lpp2012 28 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 54298236 Common deaD hypothetical protein lpp2294 247 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 54297830 Pathogen - hypothetical protein lpp1882 1 None None None 54297694 Common motC flagellar motor protein lpp1745 124 COG1291 MotA, Flagellar motor component Cell motility and secretion 54296260 Common - hypothetical protein lpp0287 178 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 54298409 Common - hypothetical protein lpp2473 192 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54296574 Common - hypothetical protein lpp0605 15 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 54296274 Pathogen - hypothetical protein lpp0303 1 None None None 54296530 Common - hypothetical protein lpp0561 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 54298906 Common tatA Putative TatA protein(twin arginine translocation) lpp2973 4 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 54296252 Common - hypothetical protein lpp0279 7 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 54297988 Pathogen - hypothetical protein lpp2044 1 None None None 54298991 Common atpE F0F1 ATP synthase subunit C lpp3058 66 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 54296780 Common neuC N-acylglucosamine 2-epimerase lpp0819 120 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 54298686 Common - hypothetical protein lpp2750 26 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 54298021 Common - hypothetical protein lpp2078 131 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 54297212 Common - hypothetical protein lpp1257 141 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 54296096 Pathogen - hypothetical protein lpp0115 1 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 54298311 Common cadA2 hypothetical protein lpp2370 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 54296017 Pathogen - hypothetical protein lpp0034 1 None None None 54297275 Common - hypothetical protein lpp1320 81 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 54298500 Common - hypothetical protein lpp2564 22 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 54298728 Common hemD Uroporphyrinogen-III synthetase lpp2792 101 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 54296284 Common - short chain dehydrogenase lpp0313 41 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54297863 Common - hypothetical protein lpp1918 21 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 54297488 Common - hypothetical protein lpp1533 134 COG0824 FcbC, Predicted thioesterase General function prediction only 54298863 Common ptsP phosphoenolpyruvate-protein phosphotransferase PtsP lpp2930 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 54297540 Common - hypothetical protein lpp1590 47 COG3682 COG3682, Predicted transcriptional regulator Transcription 54298517 Common lmxE hypothetical protein lpp2581 149 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 54297515 Common - hypothetical protein lpp1563 82 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 54297147 Common - hypothetical protein lpp1192 142 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 54297167 Common - hypothetical protein lpp1212 107 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 54298421 Pathogen - hypothetical protein lpp2485 1 None None None 54296031 Common - hypothetical protein lpp0048 176 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 54298776 Common msrA hypothetical protein lpp2840 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 54296866 Pathogen - hypothetical protein lpp0907 1 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 54298177 Common - hypothetical protein lpp2234 70 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 54296374 Common rpsQ 30S ribosomal protein S17 lpp0403 240 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 54297669 Common fliJ hypothetical protein lpp1720 16 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 54297360 Common - hypothetical protein lpp1405 24 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 54296259 Pathogen - hypothetical protein lpp0286 1 None None None 54297732 Common - hypothetical protein lpp1783 9 None None None 54297987 Common - hypothetical protein lpp2043 80 COG3965 COG3965, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 54297309 Common tmk hypothetical protein lpp1354 232 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 54298084 Common gspA global stress protein GspA lpp2141 83 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 54296550 Pathogen - hypothetical protein lpp0581 1 None None None 54297494 Common - hypothetical protein lpp1539 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 54297917 Common - hypothetical protein lpp1972 24 COG3714 COG3714, Predicted membrane protein Function unknown 54297899 Common - hypothetical protein lpp1954 92 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 54297544 Common - hypothetical protein lpp1594 68 COG0429 COG0429, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 54296899 Common - hypothetical protein lpp0940 43 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 54297386 Common bioD Dethiobiotin synthetase lpp1431 153 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 54298805 Common - hypothetical protein lpp2870 137 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 54297841 Common - hypothetical protein lpp1893 9 None None None 54297017 Common - hypothetical protein lpp1059 22 None None None 54298040 Common - hypothetical protein lpp2097 167 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 54298514 Pathogen sdcA SdcA protein, paralog of SidC (substrate of the Dot/Icm system) lpp2578 2 None None None 54297633 Common - hypothetical protein lpp1684 242 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 54298721 Common - hypothetical protein lpp2785 54 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 54297939 Common rph Ribonuclease PH (RNase PH) (tRNA nucleotidyltransferase) lpp1994 181 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 54296301 Common - hypothetical protein lpp0330 5 None None None 54297369 Common - hypothetical protein lpp1414 32 COG3737 COG3737, Uncharacterized conserved protein Function unknown 54297517 Common - hypothetical protein lpp1565 4 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 54296965 Pathogen - hypothetical protein lpp1006 1 None None None 54297686 Common - hypothetical protein lpp1737 6 COG2850 COG2850, Uncharacterized conserved protein Function unknown 54296154 Common lvhB9 Legionella vir homologue protein lpp0177 55 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 54296598 Common - hypothetical protein lpp0629 186 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 54296817 Common - hypothetical protein lpp0857 60 None None None 54296856 Common trpG Anthranilate synthase component II lpp0897 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 54298234 Pathogen - hypothetical protein lpp2292 1 None None None 54297160 Common cydB cytochrome d ubiquinol oxidase subunit II lpp1205 154 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 54296052 Pathogen - hypothetical protein lpp0070 1 None None None 54297201 Common nlpD novel lipoprotein homolog NlpD lpp1246 150 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 54296247 Common - hypothetical protein lpp0274 192 COG0583 LysR, Transcriptional regulator Transcription 54298485 Common - hypothetical protein lpp2549 149 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 54298709 Pathogen - hypothetical protein lpp2773 1 None None None 54298362 Common - hypothetical protein lpp2425 3 None None None 54297028 Pathogen - hypothetical protein lpp1070 4 None None None 54298223 Common - hypothetical protein lpp2281 207 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 54298369 Common - hypothetical protein lpp2433 11 None None None 54296610 Common - hypothetical protein lpp0641 53 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 54297794 Pathogen - hypothetical protein lpp1845 1 None None None 54297621 Common astD Succinylglutamic semialdehyde dehydrogenase lpp1672 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 54297931 Pathogen - hypothetical protein lpp1986 1 None None None 54297249 Common flaA flagellin lpp1294 134 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 54298196 Common - hypothetical protein lpp2254 111 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 54295993 Common - hypothetical protein lpp0010 230 COG2262 HflX, GTPases General function prediction only 54297220 Common - hypothetical protein lpp1265 72 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 54298619 Common - hypothetical protein lpp2683 75 COG0795 COG0795, Predicted permeases General function prediction only 54297055 Common - hypothetical protein lpp1100 4 None None None 54296504 Common - hypothetical protein lpp0535 51 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 54298816 Common - hypothetical protein lpp2881 15 COG4874 COG4874, Uncharacterized protein conserved in bacteria containing a pentein-type domain Function unknown 54297294 Common dnaQ hypothetical protein lpp1339 186 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 54297947 Common - hypothetical protein lpp2002 101 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 54297078 Common - hypothetical protein lpp1123 112 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 54298382 Common kup hypothetical protein lpp2446 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 54299002 Common - hypothetical protein lpp3069 93 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 54297559 Common - hypothetical protein lpp1609 2 None None None 54298020 Common - hypothetical protein lpp2077 84 COG0583 LysR, Transcriptional regulator Transcription 54298969 Common rnsT ribonuclease T lpp3036 53 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 54298605 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase lpp2669 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 54297071 Common - circadian clock protein KaiC lpp1116 92 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 54296236 Common - hypothetical protein lpp0262 6 None None None 54298920 Pathogen - hypothetical protein lpp2987 1 None None None 54297058 Common - hypothetical protein lpp1103 3 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 54298246 Common - hypothetical protein lpp2304 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 54298681 Common - hypothetical protein lpp2745 228 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 54297542 Pathogen - hypothetical protein lpp1592 1 None None None 54298423 Pathogen - hypothetical protein lpp2487 1 None None None 54296671 Common exoA hypothetical protein lpp0702 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 54297954 Common - hypothetical protein lpp2009 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 54298663 Common - hypothetical protein lpp2727 211 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 54296931 Common - hypothetical protein lpp0972 3 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 54298387 Pathogen - hypothetical protein lpp2451 1 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 54298399 Common - hypothetical protein lpp2463 32 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 54298976 Common - hypothetical protein lpp3043 87 COG0281 SfcA, Malic enzyme Energy production and conversion 54298616 Common - hypothetical protein lpp2680 137 COG2081 COG2081, Predicted flavoproteins General function prediction only 54296219 Pathogen - hypothetical protein lpp0245 1 None None None 54298054 Common - hypothetical protein lpp2111 4 None None None 54298030 Pathogen - hypothetical protein lpp2087 1 None None None 54297222 Common trpF N-(5'-phosphoribosyl)anthranilate isomerase lpp1267 198 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 54297210 Common - hypothetical protein lpp1255 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 54297552 Common - hypothetical protein lpp1602 230 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 54298747 Common - hypothetical protein lpp2811 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 54297164 Common - hypothetical protein lpp1209 35 COG2606 EbsC, Uncharacterized conserved protein Function unknown 54297338 Pathogen - hypothetical protein lpp1383 1 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 54298440 Pathogen - hypothetical protein lpp2504 1 None None None 54298263 Common - hypothetical protein lpp2321 169 COG1278 CspC, Cold shock proteins Transcription 54298670 Common - hypothetical protein lpp2734 65 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 54298328 Pathogen - hypothetical protein lpp2387 1 None None None 54298782 Common frgA FrgA protein lpp2846 47 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 54298813 Common - hypothetical protein lpp2878 172 COG1278 CspC, Cold shock proteins Transcription 54297769 Common udk uridine kinase lpp1820 81 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 54297747 Common - hypothetical protein lpp1798 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 54298093 Pathogen - hypothetical protein lpp2150 1 None None None 54298712 Common - hypothetical protein lpp2776 68 COG2170 COG2170, Uncharacterized conserved protein Function unknown 54297713 Common recX recombination regulator RecX lpp1764 93 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 54298172 Pathogen - hypothetical protein lpp2229 3 None None None 54297341 Pathogen - hypothetical protein lpp1386 1 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 54296689 Common - hypothetical protein lpp0720 167 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 54296843 Common - hypothetical protein lpp0884 8 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 54297777 Common clpX ATP-dependent protease ATP-binding subunit lpp1828 225 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 54298737 Pathogen - hypothetical protein lpp2801 1 None None None 54298694 Common petC hypothetical protein lpp2758 49 COG2857 CYT1, Cytochrome c1 Energy production and conversion 54296194 Common - hypothetical protein lpp0220 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 54297845 Common - hypothetical protein lpp1897 140 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 54298798 Common - hypothetical protein lpp2862 188 COG0583 LysR, Transcriptional regulator Transcription 54296461 Common hemH ferrochelatase lpp0492 158 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 54298287 Common copA2 hypothetical protein lpp2345 119 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 54297567 Common - hypothetical protein lpp1618 116 COG2353 COG2353, Uncharacterized conserved protein Function unknown 54298291 Pathogen - hypothetical protein lpp2349 1 None None None 54297799 Pathogen - hypothetical protein lpp1850 1 None None None 54297509 Common - hypothetical protein lpp1554 169 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 54296895 Pathogen - hypothetical protein lpp0936 1 None None None 54296925 Common - hypothetical protein lpp0966 57 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 54297675 Common fleR hypothetical protein lpp1726 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 54297785 Common lepB Signal peptidase I lpp1836 210 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 54296424 Common - hypothetical protein lpp0454 143 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 54298519 Common - hypothetical protein lpp2583 54 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 54298881 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA lpp2948 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 54296442 Pathogen - hypothetical protein lpp0473 1 None None None 54297082 Common - hypothetical protein lpp1127 7 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 54298801 Common - hypothetical protein lpp2866 20 COG2234 Iap, Predicted aminopeptidases General function prediction only 54296210 Common - hypothetical protein lpp0236 11 COG3207 DIT1, Pyoverdine/dityrosine biosynthesis protein Secondary metabolites biosynthesis, transport, and catabolism 54298767 Common nuoF NADH dehydrogenase I chain F lpp2831 168 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 54297471 Common - hypothetical protein lpp1516 218 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 54296961 Pathogen lidA LidA protein, substrate of the Dot/Icm system lpp1002 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54296437 Pathogen - hypothetical protein lpp0468 1 None None None 54298758 Common - hypothetical protein lpp2822 179 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 54298593 Common - hypothetical protein lpp2657 81 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 54296833 Common mreC Rod shape-determining protein MreC lpp0874 153 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 54298186 Pathogen - hypothetical protein lpp2243 1 None None None 54298617 Common - hypothetical protein lpp2681 45 COG1434 COG1434, Uncharacterized conserved protein Function unknown 54297976 Pathogen - hypothetical protein lpp2031 1 None None None 54296889 Common - hypothetical protein lpp0930 234 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 54298622 Common - hypothetical protein lpp2686 15 None None None 54297922 Pathogen - hypothetical protein lpp1977 1 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 54297348 Common cpxR transcriptional regulatory protein CpxR lpp1393 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 54298230 Common kdtA 3-Deoxy-D-manno-oct-2-ulosonic acid transferase lpp2288 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 54298825 Common - thiopurine S-methyltransferase lpp2892 36 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 54296050 Common - hypothetical protein lpp0068 12 None None None 54297740 Common - hypothetical protein lpp1791 174 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 54297318 Common - hypothetical protein lpp1363 19 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 54298373 Common - hypothetical protein lpp2437 11 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 54298432 Common - hypothetical protein lpp2496 6 None None None 54297300 Pathogen - hypothetical protein lpp1345 1 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 54298929 Common panD aspartate alpha-decarboxylase lpp2996 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 54297886 Pathogen - hypothetical protein lpp1941 1 None None None 54297658 Common - hypothetical protein lpp1709 5 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 54298522 Pathogen - hypothetical protein lpp2586 1 None None None 54297051 Common - hypothetical protein lpp1093 172 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 54296666 Pathogen - hypothetical protein lpp0697 1 None None None 54296864 Common - hypothetical protein lpp0905 100 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 54298082 Pathogen - hypothetical protein lpp2139 1 None None None 54296493 Common icmF hypothetical protein lpp0524 42 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 54297594 Common purD Phosphoribosylamine-glycine ligase lpp1645 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 54298456 Common - hypothetical protein lpp2520 84 COG2153 ElaA, Predicted acyltransferase General function prediction only 54296602 Common - hypothetical protein lpp0633 137 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 54297409 Common - hypothetical protein lpp1454 158 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 54296684 Common - hypothetical protein lpp0715 145 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 54298129 Common - hypothetical protein lpp2186 10 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54297330 Common kcy Cytidylate kinase lpp1375 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 54298705 Common infC translation initiation factor IF-3 lpp2769 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 54298533 Common - hypothetical protein lpp2597 28 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 54296912 Common - hypothetical protein lpp0953 79 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 54296766 Common - hypothetical protein lpp0805 19 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 54298789 Common - hypothetical protein lpp2853 36 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 54297003 Common - hypothetical protein lpp1044 19 COG4734 ArdA, Antirestriction protein General function prediction only 54297023 Pathogen - hypothetical protein lpp1065 1 None None None 54297101 Pathogen - hypothetical protein lpp1146 1 None None None 54296167 Pathogen - hypothetical protein lpp0190 1 None None None 54296814 Common sdhL hypothetical protein lpp0854 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 54296239 Common - hypothetical protein lpp0266 3 COG4852 COG4852, Predicted membrane protein Function unknown 54296566 Common kgd alpha-ketoglutarate decarboxylase lpp0597 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 54296528 Common - hypothetical protein lpp0559 42 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 54298437 Common - hypothetical protein lpp2501 36 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 54296639 Common queF 7-cyano-7-deazaguanine reductase lpp0670 81 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 54298334 Common - hypothetical protein lpp2393 22 None None None 54296738 Common - hypothetical protein lpp0771 73 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 54296552 Pathogen - hypothetical protein lpp0583 1 None None None 54297238 Common - hypothetical protein lpp1283 2 None None None 54297311 Common pilZ hypothetical protein lpp1356 34 COG3215 PilZ, Tfp pilus assembly protein PilZ Cell motility and secretion / Intracellular trafficking and secretion 54297325 Common gltA citrate synthase lpp1370 193 COG0372 GltA, Citrate synthase Energy production and conversion 54297618 Common umuD hypothetical protein lpp1669 143 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 54298945 Common - hypothetical protein lpp3012 123 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 54297281 Common - hypothetical protein lpp1326 173 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 54297692 Common - hypothetical protein lpp1743 2 None None None 54298756 Common infB translation initiation factor IF-2 lpp2820 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 54298888 Common - hypothetical protein lpp2955 5 None None None 54297708 Common - hypothetical protein lpp1759 59 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 54297993 Pathogen - hypothetical protein lpp2049 1 None None None 54297885 Common - hypothetical protein lpp1940 7 None None None 54298132 Common - hypothetical protein lpp2189 82 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 54297287 Common - hypothetical protein lpp1332 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 54297963 Common - hypothetical protein lpp2018 11 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 54298915 Pathogen - hypothetical protein lpp2982 1 None None None 54296513 Common rpmB 50S ribosomal protein L28 lpp0544 164 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 54296628 Common - hypothetical protein lpp0659 49 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 54297377 Common - hypothetical protein lpp1422 37 COG4582 COG4582, Uncharacterized protein conserved in bacteria Function unknown 54297533 Common - hypothetical protein lpp1583 6 COG0456 RimI, Acetyltransferases General function prediction only 54295986 Common recF RecF recombinational DNA repair ATPase lpp0003 154 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 54296304 Common - hypothetical protein lpp0333 157 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 54296456 Common eda hypothetical protein lpp0487 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 54298025 Pathogen - hypothetical protein lpp2082 1 None None None 54298643 Common - translation-associated GTPase lpp2707 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 54296945 Common ald hypothetical protein lpp0986 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 54299000 Common - hypothetical protein lpp3067 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 54296609 Common - hypothetical protein lpp0640 197 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 54297912 Pathogen - hypothetical protein lpp1967 1 COG4643 COG4643, Uncharacterized protein conserved in bacteria Function unknown 54296372 Common rplP 50S ribosomal protein L16 lpp0401 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 54297434 Common pilB pilus assembly protein PilB lpp1479 221 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 54298087 Pathogen - hypothetical protein lpp2144 1 None None None 54296071 Common - hypothetical protein lpp0089 7 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 54298142 Common - hypothetical protein lpp2199 141 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 54298345 Common - hypothetical protein lpp2404 20 None None None 54298321 Pathogen - hypothetical protein lpp2380 1 None None None 54296030 Pathogen - hypothetical protein lpp0047 1 None None None 54296037 Common prpB 2-methylisocitrate lyase lpp0054 135 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 54297495 Common - hypothetical protein lpp1540 24 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 54296041 Common - hypothetical protein lpp0058 4 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 54296824 Common - hypothetical protein lpp0865 141 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 54297132 Pathogen - hypothetical protein lpp1177 1 None None None 54296808 Common - hypothetical protein lpp0848 64 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 54296379 Common rpsH 30S ribosomal protein S8 lpp0408 238 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 54296740 Common - hypothetical protein lpp0779 66 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 54298653 Common - hypothetical protein lpp2717 25 COG3911 COG3911, Predicted ATPase General function prediction only 54296585 Common mutM hypothetical protein lpp0616 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 54296793 Common - hypothetical protein lpp0833 75 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 54296974 Common - hypothetical protein lpp1015 209 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 54297660 Common - hypothetical protein lpp1711 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 54297111 Pathogen - hypothetical protein lpp1156 1 None None None 54297872 Common - hypothetical protein lpp1927 30 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 54296125 Pathogen - hypothetical protein lpp0144 1 COG3360 COG3360, Uncharacterized conserved protein Function unknown 54298498 Common - hypothetical protein lpp2562 25 COG5310 COG5310, Homospermidine synthase Secondary metabolites biosynthesis, transport, and catabolism 54296907 Common dapE succinyl-diaminopimelate desuccinylase lpp0948 208 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 54296478 Pathogen icmR hypothetical protein lpp0509 1 None None None 54298116 Pathogen - hypothetical protein lpp2173 1 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 54296957 Common ribF Riboflavin biosynthesis protein RibF (Riboflavin kinase/FMN adenylyltransferase) lpp0998 211 COG0196 RibF, FAD synthase Coenzyme metabolism 54297113 Common - hypothetical protein lpp1158 10 COG2234 Iap, Predicted aminopeptidases General function prediction only 54296117 Common - hypothetical protein lpp0136 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 54296101 Common - hypothetical protein lpp0120 134 COG2252 COG2252, Permeases General function prediction only 54296730 Common - hypothetical protein lpp0761 70 COG2391 COG2391, Predicted transporter component General function prediction only 54296643 Common - hypothetical protein lpp0674 27 COG5579 COG5579, Uncharacterized conserved protein Function unknown 54296547 Common - hypothetical protein lpp0578 4 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 54297195 Common - hypothetical protein lpp1240 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 54298447 Pathogen - hypothetical protein lpp2511 1 None None None 54296690 Common rpe ribulose-phosphate 3-epimerase lpp0721 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 54296484 Common icmL/dotI hypothetical protein lpp0515 9 None None None 54298445 Common - hypothetical protein lpp2509 67 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 54296277 Pathogen - hypothetical protein lpp0306 1 None None None 54297392 Pathogen - hypothetical protein lpp1437 1 None None None 54297155 Common hisC Histidinol-phosphate aminotransferase (Imidazole acetol-phosphate transaminase) lpp1200 236 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 54298217 Pathogen - hypothetical protein lpp2275 1 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 54297806 Common - hypothetical protein lpp1857 6 None None None 54298905 Common ubiB hypothetical protein lpp2972 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 54296854 Common trpC indole-3-glycerol phosphate synthase lpp0895 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 54296269 Pathogen - hypothetical protein lpp0298 1 None None None 54297985 Common - hypothetical protein lpp2041 175 COG1278 CspC, Cold shock proteins Transcription 54298396 Common - hypothetical protein lpp2460 16 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 54298854 Common - pteridine reductase lpp2921 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54296139 Common - hypothetical protein lpp0161 96 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 54297415 Common aceF dihydrolipoamide acetyltransferase lpp1460 204 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 54297780 Pathogen - hypothetical protein lpp1831 1 None None None 54297549 Common - hypothetical protein lpp1599 50 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 54298273 Common - hypothetical protein lpp2331 178 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 54297583 Pathogen - hypothetical protein lpp1634 1 None None None 54296946 Common mrcA hypothetical protein lpp0987 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 54296427 Common - hypothetical protein lpp0458 35 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 54297170 Common - hypothetical protein lpp1215 32 COG3911 COG3911, Predicted ATPase General function prediction only 54298866 Pathogen - hypothetical protein lpp2933 1 None None None 54297525 Common - hypothetical protein lpp1573 74 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 54297255 Common - hypothetical protein lpp1300 66 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 54296363 Common tufA elongation factor Tu lpp0392 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 54297846 Common - hypothetical protein lpp1898 145 COG1146 COG1146, Ferredoxin Energy production and conversion 54298175 Common lly 4-hydroxyphenylpyruvate dioxygenase (legiolysin) lpp2232 78 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 54297039 Pathogen - hypothetical protein lpp1081 1 None None None 54297635 Common - hypothetical protein lpp1686 216 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 54298160 Common cbpA hypothetical protein lpp2217 234 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 54296749 Pathogen - hypothetical protein lpp0788 1 None None None 54298487 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase lpp2551 178 COG0756 Dut, dUTPase Nucleotide transport and metabolism 54296099 Common - hypothetical protein lpp0118 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 54297327 Common gyrA DNA gyrase, subunit A, type II topoisomerase lpp1372 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 54297893 Pathogen - hypothetical protein lpp1948 1 None None None 54298462 Pathogen - hypothetical protein lpp2526 2 None None None 54298042 Pathogen - hypothetical protein lpp2099 1 None None None 54297420 Common - hypothetical protein lpp1465 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 54298580 Pathogen - hypothetical protein lpp2644 1 None None None 54298692 Common sspB ClpXP protease specificity-enhancing factor lpp2756 64 COG2969 SspB, Stringent starvation protein B General function prediction only 54296772 Common - hypothetical protein lpp0811 56 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54296909 Common - hypothetical protein lpp0950 29 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 54297427 Common lssA Legionella secretion system protein A lpp1472 48 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 54296831 Common - hypothetical protein lpp0872 69 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 54298066 Common - hypothetical protein lpp2123 202 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 54298102 Common - hypothetical protein lpp2159 175 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 54296015 Pathogen - hypothetical protein lpp0032 1 None None None 54296836 Common - hypothetical protein lpp0877 3 None None None 54295997 Common - hypothetical protein lpp0014 79 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 54298730 Common hemY protoporphyrinogen IX and coproporphyrinogen III oxidase HemY lpp2794 58 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 54298983 Common - hypothetical protein lpp3050 50 COG5495 COG5495, Uncharacterized conserved protein Function unknown 54298840 Common - hypothetical protein lpp2907 17 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 54298739 Common - hypothetical protein lpp2803 169 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 54297352 Common - hypothetical protein lpp1397 127 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 54298999 Common - hypothetical protein lpp3066 46 COG3107 LppC, Putative lipoprotein General function prediction only 54298259 Common - hypothetical protein lpp2317 45 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 54296337 Common - hypothetical protein lpp0366 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 54296009 Common - hypothetical protein lpp0026 160 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 54296102 Common - hypothetical protein lpp0121 10 COG1723 COG1723, Uncharacterized conserved protein Function unknown 54298407 Common - hypothetical protein lpp2471 2 None None None 54296636 Common - hypothetical protein lpp0667 63 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 54296406 Common - hypothetical protein lpp0435 103 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 54298019 Pathogen - hypothetical protein lpp2076 1 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 54297179 Common flgB flagellar basal body rod protein FlgB lpp1224 89 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 54297702 Common fliP flagellar biosynthesis protein FliP lpp1753 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 54298001 Common - hypothetical protein lpp2058 102 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 54296700 Common - hypothetical protein lpp0731 23 None None None 54296201 Pathogen - hypothetical protein lpp0227 4 None None None 54298631 Common - hypothetical protein lpp2695 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 54298488 Common dfp hypothetical protein lpp2552 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 54296526 Common argH Argininosuccinate lyase lpp0557 235 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 54296515 Common - hypothetical protein lpp0546 89 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 54298316 Common - hypothetical protein lpp2375 5 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 54296926 Common - hypothetical protein lpp0967 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54296819 Pathogen - hypothetical protein lpp0860 1 None None None 54296255 Common - hypothetical protein lpp0282 179 COG0583 LysR, Transcriptional regulator Transcription 54297828 Pathogen - hypothetical protein lpp1880 3 COG5371 COG5371, Golgi nucleoside diphosphatase Carbohydrate transport and metabolism / Posttranslational modification, protein turnover, chaperones 54296936 Common ftsI Peptidoglycan synthetase FtsI precursor lpp0977 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 54296993 Pathogen - hypothetical protein lpp1034 1 None None None 54298207 Common - hypothetical protein lpp2265 43 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 54298478 Common - hypothetical protein lpp2542 3 COG3376 HoxN, High-affinity nickel permease Inorganic ion transport and metabolism 54297858 Pathogen - hypothetical protein lpp1913 1 None None None 54297538 Common - hypothetical protein lpp1588 37 COG2602 COG2602, Beta-lactamase class D Defense mechanisms 54297630 Pathogen - hypothetical protein lpp1681 1 None None None 54296222 Common - hypothetical protein lpp0248 176 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 54296355 Common rplA 50S ribosomal protein L1 lpp0384 247 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 54296173 Common - hypothetical protein lpp0196 22 COG2253 COG2253, Uncharacterized conserved protein Function unknown 54297907 Common - hypothetical protein lpp1962 2 None None None 54298477 Common hypA Hydrogenase nickel incorporation protein HypA lpp2541 93 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 54296343 Pathogen - hypothetical protein lpp0372 1 None None None 54296388 Common rpsK 30S ribosomal protein S11 lpp0417 246 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 54298034 Common - hypothetical protein lpp2091 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 54296047 Common hipA HipA protein, DNA binding regulator lpp0064 62 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 54297574 Pathogen - hypothetical protein lpp1625 1 None None None 54297600 Common - hypothetical protein lpp1651 9 None None None 54298536 Common - hypothetical protein lpp2600 151 COG1959 COG1959, Predicted transcriptional regulator Transcription 54298470 Common - hypothetical protein lpp2534 117 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 54297648 Common trpE Anthranilate synthase lpp1699 235 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 54296717 Common - hypothetical protein lpp0748 8 None None None 54296475 Pathogen - hypothetical protein lpp0506 1 None None None 54297607 Pathogen - hypothetical protein lpp1658 1 None None None 54297186 Common flgI flagellar basal body P-ring protein lpp1231 103 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 54296596 Common - hypothetical protein lpp0627 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 54296381 Common rplR 50S ribosomal protein L18 lpp0410 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 54297466 Common fadD/lidS hypothetical protein lpp1511 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54297081 Common - hypothetical protein lpp1126 149 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 54298358 Pathogen - hypothetical protein lpp2420 1 None None None 54297346 Pathogen - hypothetical protein lpp1391 1 None None None 54298823 Common - hypothetical protein lpp2890 132 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 54296152 Common lvhB6 Legionella vir homologue protein lpp0175 36 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 54295984 Common dnaA Chromosomal replication initiator protein DnaA lpp0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 54297367 Common rumA 23S rRNA 5-methyluridine methyltransferase lpp1412 201 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 54298934 Common ubiD hypothetical protein lpp3001 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 54296457 Common - hypothetical protein lpp0488 110 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54296661 Common - hypothetical protein lpp0692 159 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 54296691 Common - hypothetical protein lpp0722 23 COG2259 COG2259, Predicted membrane protein Function unknown 54298774 Common tpi triosephosphate isomerase lpp2838 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 54298803 Common rep ATP-dependent DNA helicase Rep lpp2868 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 54298219 Common xseB hypothetical protein lpp2277 143 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 54296821 Common nadB L-aspartate oxidase lpp0862 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 54297718 Common - hypothetical protein lpp1769 93 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 54297711 Pathogen - hypothetical protein lpp1762 1 None None None 54298940 Common - hypothetical protein lpp3007 9 None None None 54296577 Common - hypothetical protein lpp0608 31 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 54296782 Common - hypothetical protein lpp0821 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 54298707 Pathogen - hypothetical protein lpp2771 1 None None None 54298974 Common - hypothetical protein lpp3041 23 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 54297623 Common - hypothetical protein lpp1674 3 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 54297818 Common - hypothetical protein lpp1870 53 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 54297019 Pathogen - hypothetical protein lpp1061 1 None None None 54296054 Common - hypothetical protein lpp0072 139 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 54298563 Common - hypothetical protein lpp2627 9 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 54296240 Common - hypothetical protein lpp0267 76 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 54297945 Common - hypothetical protein lpp2000 5 None None None 54298367 Common - hypothetical protein lpp2431 20 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 54297615 Pathogen - hypothetical protein lpp1666 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54298546 Pathogen - hypothetical protein lpp2610 1 None None None 54298296 Common - hypothetical protein lpp2354 2 None None None 54296206 Common - hypothetical protein lpp0232 5 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 54297122 Common - hypothetical protein lpp1167 47 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 54296313 Common - hypothetical protein lpp0342 42 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 54296450 Common - hypothetical protein lpp0481 159 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 54297350 Common - hypothetical protein lpp1395 145 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 54297026 Pathogen - hypothetical protein lpp1068 1 None None None 54297796 Common - hypothetical protein lpp1847 55 COG2862 COG2862, Predicted membrane protein Function unknown 54298573 Pathogen sidF Substrate of the Dot/Icm system lpp2637 1 COG0170 SEC59, Dolichol kinase Lipid metabolism 54296234 Common qxtB hypothetical protein lpp0260 151 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 54296249 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit lpp0276 195 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 54297450 Common pcnB Poly(A) polymerase (PAP) (Plasmid copy number protein) lpp1495 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 54298829 Common - hypothetical protein lpp2896 38 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54298598 Common ftsZ cell division protein FtsZ lpp2662 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 54296262 Common - hypothetical protein lpp0291 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54298874 Common metG methionyl-tRNA synthetase lpp2941 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54297011 Pathogen - hypothetical protein lpp1053 1 None None None 54297190 Common - hypothetical protein lpp1235 11 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 54297242 Common rluD Ribosomal large subunit pseudouridine synthase D (Pseudouridylate synthase) (Uracil hydrolyase) lpp1287 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 54296084 Common - hypothetical protein lpp0102 126 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 54298638 Common obgE GTPase ObgE lpp2702 249 COG0536 Obg, Predicted GTPase General function prediction only 54298415 Common - hypothetical protein lpp2479 18 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 54296094 Common polA DNA polymerase I lpp0113 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 54296065 Common - hypothetical protein lpp0083 74 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 54297734 Pathogen - hypothetical protein lpp1785 1 None None None 54296276 Common - hypothetical protein lpp0305 13 COG3791 COG3791, Uncharacterized conserved protein Function unknown 54297197 Common - hypothetical protein lpp1242 8 COG5513 COG5513, Predicted secreted protein Function unknown 54297765 Pathogen - hypothetical protein lpp1816 1 None None None 54298958 Common - hypothetical protein lpp3025 7 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 54297486 Common tolR hypothetical protein lpp1531 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 54297000 Pathogen - hypothetical protein lpp1041 1 None None None 54298589 Common - hypothetical protein lpp2653 115 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 54296330 Common - formate dehydrogenase lpp0359 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 54296725 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase lpp0756 192 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 54296114 Pathogen - hypothetical protein lpp0133 1 None None None 54297273 Common glnA glutamine synthetase lpp1318 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 54296981 Common - hypothetical protein lpp1022 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 54298313 Common helB HelB protein lpp2372 108 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 54298591 Common - hypothetical protein lpp2655 3 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 54297062 Common - hypothetical protein lpp1107 5 COG2510 COG2510, Predicted membrane protein Function unknown 54296401 Pathogen - hypothetical protein lpp0430 1 None None None 54298502 Pathogen - hypothetical protein lpp2566 1 None None None 54298811 Common - hypothetical protein lpp2876 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 54297773 Common - hypothetical protein lpp1824 4 None None None 54296324 Common - hypothetical protein lpp0353 206 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 54296021 Common - hypothetical protein lpp0038 14 None None None 54298678 Common icmW Intracellular multiplication protein IcmW lpp2742 3 None None None 54296286 Common - hypothetical protein lpp0315 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 54298265 Common - hypothetical protein lpp2323 76 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 54296659 Common tdk thymidine kinase lpp0690 100 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 54298818 Common - hypothetical protein lpp2884 82 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 54297865 Common - hypothetical protein lpp1920 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 54296010 Common - hypothetical protein lpp0027 165 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 54298023 Common - hypothetical protein lpp2080 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54296500 Common dcoA pyruvate carboxylase subunit B lpp0531 207 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 54296487 Pathogen icmG/dotF hypothetical protein lpp0518 3 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 54298541 Pathogen - hypothetical protein lpp2605 1 None None None 54296394 Common - enoyl-(acyl carrier protein) reductase lpp0423 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54296612 Common - hypothetical protein lpp0643 184 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 54296507 Common - hypothetical protein lpp0538 19 None None None 54296619 Common - hypothetical protein lpp0650 73 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 54297009 Pathogen - hypothetical protein lpp1050 1 None None None 54297749 Pathogen - hypothetical protein lpp1800 1 None None None 54297149 Common - hypothetical protein lpp1194 104 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 54298032 Pathogen - hypothetical protein lpp2089 1 None None None 54298194 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase lpp2252 220 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 54296736 Common - hypothetical protein lpp0767 11 None None None 54298496 Pathogen - hypothetical protein lpp2560 1 None None None 54298835 Common - hypothetical protein lpp2902 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 54296128 Pathogen - hypothetical protein lpp0147 1 None None None 54297138 Common ribH riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synthase) lpp1183 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 54296463 Common - hypothetical protein lpp0494 63 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 54296035 Pathogen - hypothetical protein lpp0052 1 None None None 54297110 Common - hypothetical protein lpp1155 52 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 54298074 Common - hypothetical protein lpp2131 237 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 54297592 Common - hypothetical protein lpp1643 7 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 54297264 Pathogen sidG SidG protein, substrate of the Dot/Icm system lpp1309 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54296359 Common rpoC DNA-directed RNA polymerase subunit beta' lpp0388 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 54296440 Pathogen - hypothetical protein lpp0471 1 None None None 54296983 Common dnaE DNA polymerase III, alpha chain lpp1024 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 54297120 Common - hypothetical protein lpp1165 134 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54298115 Common - hypothetical protein lpp2172 2 None None None 54296801 Common lag-1 O-acetyltransferase lpp0841 17 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 54298784 Common - hypothetical protein lpp2848 186 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 54297876 Common - hypothetical protein lpp1931 2 None None None 54298740 Common recR Recombination and repair protein recR lpp2804 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 54296646 Common - hypothetical protein lpp0677 3 None None None 54298148 Common - hypothetical protein lpp2205 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 54298765 Common nuoH NADH-quinone oxidoreductase chain H lpp2829 189 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 54296954 Common aroB 3-dehydroquinate synthase lpp0995 210 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 54297150 Common hisI phosphoribosyl-AMP cyclohydrolase (PRA-CH) / phosphoribosyl-ATP pyrophosphatase (PRA-PH) lpp1195 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 54298806 Common - hypothetical protein lpp2871 5 None None None 54296187 Pathogen - hypothetical protein lpp0213 1 None None None 54296482 Common lphA hypothetical protein lpp0513 37 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 54296318 Common - hypothetical protein lpp0347 141 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54296396 Common - hypothetical protein lpp0425 6 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 54296776 Common hisF hypothetical protein lpp0815 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 54296976 Common - hypothetical protein lpp1017 140 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 54298256 Common - hypothetical protein lpp2314 145 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 54297990 Common - hypothetical protein lpp2046 72 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 54297835 Common gacS/letS Legionella transmission sensor LetS lpp1887 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 54298651 Common panB hypothetical protein lpp2715 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 54296162 Common - hypothetical protein lpp0185 5 None None None 54296067 Common - hypothetical protein lpp0085 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 54296295 Pathogen - hypothetical protein lpp0324 1 None None None 54296107 Pathogen - hypothetical protein lpp0126 1 None None None 54298848 Common - hypothetical protein lpp2915 27 None None None 54298458 Pathogen - hypothetical protein lpp2522 1 None None None 54298360 Common - hypothetical protein lpp2423 27 COG5340 COG5340, Predicted transcriptional regulator Transcription 54298659 Common ftsE hypothetical protein lpp2723 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 54296649 Common - hypothetical protein lpp0680 190 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 54297202 Common rpoS RNA polymerase sigma factor RpoS lpp1247 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 54298753 Common rpsO 30S ribosomal protein S15 lpp2817 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 54297888 Pathogen - hypothetical protein lpp1943 1 COG3774 OCH1, Mannosyltransferase OCH1 and related enzymes Cell envelope biogenesis, outer membrane 54298418 Pathogen - hypothetical protein lpp2482 1 None None None 54298646 Pathogen - hypothetical protein lpp2710 1 None None None 54296727 Common - putative ABC transporter ATP-binding protein lpp0758 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 54298937 Common - hypothetical protein lpp3004 207 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 54297680 Common trxB Thioredoxin reductase lpp1731 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 54297983 Common - hypothetical protein lpp2038 75 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 54298289 Pathogen - hypothetical protein lpp2347 1 None None None 54298903 Common ubiE Ubiquinone/menaquinone biosynthesis methyltransferase lpp2970 218 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 54297153 Common hisH imidazole glycerol phosphate synthase subunit HisH lpp1198 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 54298510 Common - hypothetical protein lpp2574 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 54296542 Common lpxA UDP-N-acetylglucosamine acyltransferase lpp0573 166 COG1043 LpxA, Acyl- acyl carrier protein 54296180 Common - hypothetical protein lpp0204 5 None None None 54298356 Pathogen - hypothetical protein lpp2418 1 None None None 54298552 Common - hypothetical protein lpp2616 63 COG0073 ARC1, EMAP domain General function prediction only 54299009 Common rnpA hypothetical protein lpp3076 82 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 54298205 Pathogen - hypothetical protein lpp2263 1 None None None 54296554 Common - hypothetical protein lpp0585 33 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 54296991 Common - hypothetical protein lpp1032 139 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 54297045 Common - hypothetical protein lpp1087 3 COG3311 AlpA, Predicted transcriptional regulator Transcription 54298749 Common - hypothetical protein lpp2813 235 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 54298201 Pathogen - hypothetical protein lpp2259 1 None None None 54298449 Pathogen - hypothetical protein lpp2513 1 None None None 54296578 Common - hypothetical protein lpp0609 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 54297021 Common - hypothetical protein lpp1063 21 None None None 54296308 Pathogen - hypothetical protein lpp0337 1 None None None 54297809 Common - hypothetical protein lpp1860 134 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 54296564 Common sdhA succinate dehydrogenase flavoprotein subunit lpp0595 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 54297710 Pathogen - hypothetical protein lpp1761 1 COG5185 HEC1, Protein involved in chromosome segregation, interacts with SMC proteins Cell division and chromosome partitioning 54296959 Common lspA Lipoprotein signal peptidase lpp1000 196 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54299004 Common - hypothetical protein lpp3071 8 None None None 54297231 Common - hypothetical protein lpp1276 153 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 54297286 Common - hypothetical protein lpp1331 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 54297421 Common - hypothetical protein lpp1466 157 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 54297745 Common - hypothetical protein lpp1796 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 54297995 Common - hypothetical protein lpp2052 10 None None None 54296303 Pathogen - hypothetical protein lpp0332 1 None None None 54298868 Common lrsB arsenite efflux membrane component-like protein lpp2935 123 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 54297347 Common cpxA Sensor histidine kinase lpp1392 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 54296626 Common - hypothetical protein lpp0657 154 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 54298815 Common - hypothetical protein lpp2880 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 54297575 Common - hypothetical protein lpp1626 40 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 54298442 Common - hypothetical protein lpp2506 113 COG0431 COG0431, Predicted flavoprotein General function prediction only 54298556 Common - hypothetical protein lpp2620 8 None None None 54296822 Common purB adenylosuccinate lyase lpp0863 235 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 54297467 Common - hypothetical protein lpp1512 163 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 54296624 Common - hypothetical protein lpp0655 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 54296078 Pathogen - hypothetical protein lpp0096 1 None None None 54297457 Common - hypothetical protein lpp1502 72 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 54296571 Pathogen letE transmission trait enhancer protein LetE lpp0602 1 None None None 54297717 Common mutS DNA mismatch repair protein lpp1768 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 54297996 Pathogen - hypothetical protein lpp2053 1 None None None 54297375 Common mutT Mutator protein MutT lpp1420 172 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 54296082 Pathogen - hypothetical protein lpp0100 1 None None None 54297613 Common ubiG 3-demethylubiquinone-9 3-methyltransferase lpp1664 177 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 54296412 Pathogen - hypothetical protein lpp0442 1 None None None 54298796 Common - hypothetical protein lpp2860 233 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 54298897 Common - hypothetical protein lpp2964 42 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 54296490 Pathogen icmJ/dotN hypothetical protein lpp0521 5 None None None 54296174 Common - hypothetical protein lpp0197 135 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 54296949 Common pilN Tfp pilus assembly protein PilN lpp0990 43 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 54298017 Common ceaB Chemiosmotic efflux system protein B-like protein lpp2074 175 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 54298085 Common - hypothetical protein lpp2142 128 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 54298680 Common lphB unknown, LphB lpp2744 6 None None None 54298742 Common - hypothetical protein lpp2806 7 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 54298483 Common - hypothetical protein lpp2547 87 COG2128 COG2128, Uncharacterized conserved protein Function unknown 54297565 Common - hypothetical protein lpp1616 80 COG2353 COG2353, Uncharacterized conserved protein Function unknown 54298599 Common ftsA ATP-binding cell division protein FtsA lpp2663 177 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 54298402 Common - hypothetical protein lpp2466 5 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 54296742 Common - hypothetical protein lpp0781 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 54296189 Pathogen - hypothetical protein lpp0215 1 None None None 54296891 Common - hypothetical protein lpp0932 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 54298295 Common cecC Chemiosmotic efflux system C protein C lpp2353 58 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54298057 Pathogen - hypothetical protein lpp2114 1 None None None 54296229 Common - hypothetical protein lpp0255 104 COG0393 COG0393, Uncharacterized conserved protein Function unknown 54297185 Common flgH flagellar basal body L-ring protein lpp1230 99 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 54298524 Pathogen - hypothetical protein lpp2588 1 None None None 54298122 Common - hypothetical protein lpp2179 2 None None None 54297964 Common - hypothetical protein lpp2019 189 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 54296218 Common htpX hypothetical protein lpp0244 192 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 54298332 Common - hypothetical protein lpp2391 21 None None None 54297608 Common acnA aconitate hydratase lpp1659 223 COG1048 AcnA, Aconitase A Energy production and conversion 54298430 Common - malonate decarboxylase subunit beta lpp2494 171 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 54296432 Common rplS 50S ribosomal protein L19 lpp0463 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 54296852 Common - hypothetical protein lpp0893 86 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 54297089 Pathogen - hypothetical protein lpp1134 1 None None None 54297428 Common lssB Legionella secretion system protein B lpp1473 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 54297460 Common ndk hypothetical protein lpp1505 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 54297861 Common - hypothetical protein lpp1916 9 COG1395 COG1395, Predicted transcriptional regulator Transcription 54297677 Common - recombination factor protein RarA lpp1728 217 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 54297920 Common mltA hypothetical protein lpp1975 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 54297236 Common - hypothetical protein lpp1281 3 None None None 54298266 Common - hypothetical protein lpp2324 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 54298628 Common enhC enhanced entry protein EnhC lpp2692 107 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 54298183 Common pgsA hypothetical protein lpp2240 202 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 54297959 Common - hypothetical protein lpp2014 180 COG0628 PerM, Predicted permease General function prediction only 54297561 Common - hypothetical protein lpp1611 174 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 54297390 Common - hypothetical protein lpp1435 207 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 54298602 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase lpp2666 185 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 54297728 Common - hypothetical protein lpp1779 117 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 54298620 Common pepA hypothetical protein lpp2684 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 54296914 Common - hypothetical protein lpp0955 104 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 54296881 Common ccmE cytochrome c-type biogenesis protein CcmE lpp0922 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 54298886 Common - hypothetical protein lpp2953 68 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 54297667 Common - hypothetical protein lpp1718 3 None None None 54298588 Common topA DNA topoisomerase I lpp2652 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 54298675 Common sbpA hypothetical protein lpp2739 56 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 54298390 Common katB catalase-peroxidase KatB lpp2454 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 54296783 Common rmlC dTDP-4-dehydrorhamnose 3,5-epimerase lpp0822 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 54298284 Pathogen - hypothetical protein lpp2342 1 None None None 54298326 Pathogen - hypothetical protein lpp2385 1 None None None 54296027 Pathogen - hypothetical protein lpp0044 1 None None None 54298341 Pathogen - hypothetical protein lpp2400 1 None None None 54298244 Common nudE ADP-ribose diphosphatase NudE lpp2302 129 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 54297332 Common - hypothetical protein lpp1377 6 COG3771 COG3771, Predicted membrane protein Function unknown 54298629 Pathogen enhB enhanced entry protein EnhB lpp2693 2 None None None 54297399 Pathogen - hypothetical protein lpp1444 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54296877 Common ccmA heme exporter protein CcmA lpp0918 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 54298385 Common - hypothetical protein lpp2449 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 54297620 Common astA arginine N-succinyltransferase, beta chain lpp1671 37 COG3138 AstA, Arginine/ornithine N-succinyltransferase beta subunit Amino acid transport and metabolism 54297076 Pathogen - hypothetical protein lpp1121 1 None None None 54296298 Common - hypothetical protein lpp0327 81 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 54298094 Common - hypothetical protein lpp2151 120 COG1690 RtcB, Uncharacterized conserved protein Function unknown 54298932 Pathogen - hypothetical protein lpp2999 1 None None None 54297060 Pathogen - hypothetical protein lpp1105 1 None None None 54298099 Pathogen - hypothetical protein lpp2156 1 None None None 54296886 Common - hypothetical protein lpp0927 38 COG3360 COG3360, Uncharacterized conserved protein Function unknown 54296670 Common - hypothetical protein lpp0701 45 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 54298280 Common - hypothetical protein lpp2338 7 None None None 54296040 Common - hypothetical protein lpp0057 168 COG0583 LysR, Transcriptional regulator Transcription 54296495 Common purH hypothetical protein lpp0526 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 54298397 Pathogen - hypothetical protein lpp2461 1 None None None 54297518 Common - hypothetical protein lpp1566 60 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 54297759 Common gshB glutathione synthetase lpp1810 122 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 54297262 Common fadA acetyl-CoA acetyltransferase lpp1307 175 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 54298725 Common - hypothetical protein lpp2789 31 COG3247 HdeD, Uncharacterized conserved protein Function unknown 54296332 Pathogen - hypothetical protein lpp0361 1 None None None 54296784 Common rmlD dTDP-4-keto-L-rhamnose reductase lpp0823 173 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 54296638 Common - hypothetical protein lpp0669 34 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 54298846 Common - hypothetical protein lpp2913 47 None None None 54297224 Common trpA tryptophan synthase subunit alpha lpp1269 218 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 54298699 Common - hypothetical protein lpp2763 89 COG3411 COG3411, Ferredoxin Energy production and conversion 54296580 Common - hypothetical protein lpp0611 118 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 54297218 Common fimV FimV protein lpp1263 98 COG3170 FimV, Tfp pilus assembly protein FimV Cell motility and secretion / Intracellular trafficking and secretion 54298838 Pathogen - hypothetical protein lpp2905 2 None None None 54297511 Pathogen - hypothetical protein lpp1556 1 None None None 54297935 Common spoT guanosine-3',5'-bis(diphosphate) 3'-pyrophosphohydrolase lpp1990 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 54297531 Common - hypothetical protein lpp1581 88 COG0789 SoxR, Predicted transcriptional regulators Transcription 54298544 Pathogen - hypothetical protein lpp2608 1 None None None 54297977 Pathogen - hypothetical protein lpp2032 1 None None None 54297106 Pathogen - hypothetical protein lpp1151 1 None None None 54297403 Common aph spectinomycin phosphotransferase lpp1448 6 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 54297279 Common - hypothetical protein lpp1324 89 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 54296462 Common cspD hypothetical protein lpp0493 179 COG1278 CspC, Cold shock proteins Transcription 54296525 Common argG Argininosuccinate synthase lpp0556 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 54297143 Common - hypothetical protein lpp1188 127 COG4105 ComL, DNA uptake lipoprotein General function prediction only 54297013 Common - hypothetical protein lpp1055 37 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 54296938 Common pdxB hypothetical protein lpp0979 230 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 54298876 Pathogen - hypothetical protein lpp2943 1 None None None 54296092 Pathogen - hypothetical protein lpp0110 1 None None None 54298435 Common - hypothetical protein lpp2499 28 None None None 54296455 Common glk hypothetical protein lpp0486 89 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 54297461 Pathogen - hypothetical protein lpp1506 2 None None None 54296263 Common - hypothetical protein lpp0292 125 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54297737 Common - hypothetical protein lpp1788 185 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 54297735 Common - hypothetical protein lpp1786 14 None None None 54298833 Common - hypothetical protein lpp2900 226 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54297484 Common tolB TolB protein lpp1529 157 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 54298808 Common - hypothetical protein lpp2873 201 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 54297497 Common lidK hypothetical protein lpp1542 27 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 54298913 Pathogen - hypothetical protein lpp2980 1 None None None 54297875 Pathogen - hypothetical protein lpp1930 1 None None None 54298271 Common - hypothetical protein lpp2329 3 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 54296241 Pathogen - hypothetical protein lpp0268 1 None None None 54296220 Pathogen - hypothetical protein lpp0246 1 None None None 54298411 Pathogen - hypothetical protein lpp2475 1 None None None 54298505 Common - hypothetical protein lpp2569 105 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 54296516 Pathogen - hypothetical protein lpp0547 1 None None None 54298026 Common - hypothetical protein lpp2083 173 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 54297625 Common rrf Ribosome recycling factor lpp1676 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 54296616 Common - hypothetical protein lpp0647 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54297764 Common - hypothetical protein lpp1815 130 None None None 54297209 Common - hypothetical protein lpp1254 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 54298963 Common - hypothetical protein lpp3030 7 None None None 54297228 Pathogen - hypothetical protein lpp1273 1 None None None 54297868 Common - hypothetical protein lpp1923 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 54296509 Common - hypothetical protein lpp0540 151 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 54296930 Common - hypothetical protein lpp0971 41 COG3245 CycB, Cytochrome c5 Energy production and conversion 54298348 Common - hypothetical protein lpp2407 22 COG4734 ArdA, Antirestriction protein General function prediction only 54298889 Common - hypothetical protein lpp2956 112 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 54298548 Pathogen - hypothetical protein lpp2612 1 None None None 54297383 Common bioB Biotin synthase lpp1428 185 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 54297059 Common - methionine sulfoxide reductase B lpp1104 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 54297748 Common - hypothetical protein lpp1799 2 None None None 54297040 Common - hypothetical protein lpp1082 138 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 54296305 Common - hypothetical protein lpp0334 72 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 54296686 Common - hypothetical protein lpp0717 38 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54296969 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta lpp1010 137 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 54297163 Common - hypothetical protein lpp1208 22 None None None 54298772 Common nuoA NADH dehydrogenase I chain A lpp2836 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 54298210 Pathogen - hypothetical protein lpp2268 1 None None None 54298366 Pathogen - hypothetical protein lpp2430 1 None None None 54296709 Common - hypothetical protein lpp0740 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 54296768 Common - hypothetical protein lpp0807 7 None None None 54298044 Common - hypothetical protein lpp2101 2 None None None 54298972 Common sodB superoxide dismutase, iron lpp3039 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 54298297 Common - hypothetical protein lpp2355 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 54298173 Common - hypothetical protein lpp2230 126 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 54296056 Common - hypothetical protein lpp0074 46 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 54296137 Common prlC Oligopeptidase A lpp0156 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 54296097 Common fabF hypothetical protein lpp0116 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54296150 Pathogen lvhB7 Legionella vir homologue protein lpp0173 1 None None None 54298138 Common - hypothetical protein lpp2195 10 None None None 54298575 Common - hypothetical protein lpp2639 2 COG4870 COG4870, Cysteine protease Posttranslational modification, protein turnover, chaperones 54296232 Common - hypothetical protein lpp0258 5 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 54297298 Common - hypothetical protein lpp1343 163 COG0316 IscA, Uncharacterized conserved protein Function unknown 54296386 Common rpmJ 50S ribosomal protein L36 lpp0415 133 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 54298381 Common - hypothetical protein lpp2445 164 COG0583 LysR, Transcriptional regulator Transcription 54298154 Pathogen - hypothetical protein lpp2211 1 None None None 54297047 Common - hypothetical protein lpp1089 124 COG2320 GrpB, Uncharacterized conserved protein Function unknown 54298481 Common - hypothetical protein lpp2545 126 COG2510 COG2510, Predicted membrane protein Function unknown 54297682 Common - hypothetical protein lpp1733 109 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 54297329 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase lpp1374 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 54296316 Common pncA nicotinamidase/ pyrazinamidase lpp0345 112 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 54297721 Pathogen - hypothetical protein lpp1772 1 None None None 54298374 Pathogen - hypothetical protein lpp2438 1 None None None 54296271 Pathogen - hypothetical protein lpp0300 1 COG5278 COG5278, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 54297547 Common - hypothetical protein lpp1597 14 None None None 54298717 Pathogen - hypothetical protein lpp2781 1 None None None 54297172 Pathogen - hypothetical protein lpp1217 1 None None None 54296541 Common fabZ (3R)-hydroxymyristoyl-[acyl carrier protein]dehydratase lpp0572 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 54297943 Common - hypothetical protein lpp1998 44 None None None 54296013 Pathogen - hypothetical protein lpp0030 1 None None None 54297432 Common - hypothetical protein lpp1477 15 COG4517 COG4517, Uncharacterized protein conserved in bacteria Function unknown 54298278 Pathogen - hypothetical protein lpp2336 1 None None None 54297447 Common - hypothetical protein lpp1492 115 COG1773 COG1773, Rubredoxin Energy production and conversion 54296435 Common rpsP 30S ribosomal protein S16 lpp0466 211 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 54296601 Common - hypothetical protein lpp0632 2 None None None 54298842 Pathogen - hypothetical protein lpp2909 2 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 54296910 Common metB hypothetical protein lpp0951 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 54297291 Common - hypothetical protein lpp1336 218 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 54297317 Common - hypothetical protein lpp1362 42 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 54297880 Pathogen - hypothetical protein lpp1935 1 None None None 54296072 Common - hypothetical protein lpp0090 40 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 54296906 Common - hypothetical protein lpp0947 157 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 54297473 Common - hypothetical protein lpp1518 217 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 54297527 Common proB gamma-glutamyl kinase lpp1575 193 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 54298007 Common - hypothetical protein lpp2064 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 54298318 Pathogen - hypothetical protein lpp2377 1 None None None 54296710 Common dsbD/lidC hypothetical protein lpp0741 155 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 54297638 Common minD Septum site-determining protein (Cell division inhibitor) lpp1689 137 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 54297908 Pathogen - hypothetical protein lpp1963 1 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 54298980 Pathogen - hypothetical protein lpp3047 1 None None None 54296755 Common thiL Thiamine-monophosphate kinase lpp0794 203 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 54297704 Common fliN Flagellar motor switch protein FliN lpp1755 123 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 54296149 Common lvhB5 Legionella vir homologue protein B5 lpp0172 4 None None None 54297244 Common - hypothetical protein lpp1289 162 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 54297653 Common - hypothetical protein lpp1704 88 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 54296371 Common rpsC 30S ribosomal protein S3 lpp0400 247 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 54297698 Common flhA flagellar biosynthesis protein A lpp1749 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 54296673 Common rpmE 50S ribosomal protein L31 lpp0704 202 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 54296323 Common - hypothetical protein lpp0352 184 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 54296339 Common - hypothetical protein lpp0368 11 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 54298850 Common - hypothetical protein lpp2917 174 COG0714 COG0714, MoxR-like ATPases General function prediction only 54296449 Common - hypothetical protein lpp0480 101 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 54297169 Common - hypothetical protein lpp1214 23 COG1846 MarR, Transcriptional regulators Transcription 54298661 Common - hypothetical protein lpp2725 200 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 54298461 Common - hypothetical protein lpp2525 15 None None None 54297577 Common - hypothetical protein lpp1628 32 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 54298303 Common cebA Chemiosmotic efflux system B protein A lpp2361 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 54297459 Common - hypothetical protein lpp1504 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 54296423 Common - heat shock protein HtpX lpp0453 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 54296042 Pathogen - hypothetical protein lpp0059 1 None None None 54297036 Common - hypothetical protein lpp1078 133 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 54296614 Common - hypothetical protein lpp0645 194 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 54296140 Common - hypothetical protein lpp0162 3 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 54297097 Common potB hypothetical protein lpp1142 197 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 54298989 Common atpH hypothetical protein lpp3056 96 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 54297812 Pathogen - hypothetical protein lpp1863 2 None None None 54296964 Common recO DNA repair protein recO lpp1005 55 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 54296354 Common rplK 50S ribosomal protein L11 lpp0383 248 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 54297269 Pathogen lspI type II secretory pathway protein LspI lpp1314 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 54297803 Pathogen - hypothetical protein lpp1854 1 None None None 54297251 Common folC hypothetical protein lpp1296 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 54296447 Common - hypothetical protein lpp0478 101 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 54298425 Pathogen - hypothetical protein lpp2489 1 None None None 54298162 Common - hypothetical protein lpp2219 45 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 54296890 Common - hypothetical protein lpp0931 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 54298951 Common - hypothetical protein lpp3018 102 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 54298947 Common lpxB hypothetical protein lpp3014 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 54296842 Common - hypothetical protein lpp0883 142 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 54298577 Common - hypothetical protein lpp2641 3 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 54298727 Common hemC Porphobilinogen deaminase HemC lpp2791 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 54296593 Common - hypothetical protein lpp0624 17 None None None 54297108 Pathogen - hypothetical protein lpp1153 1 None None None 54298108 Common - hypothetical protein lpp2165 105 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 54296798 Common wzt ABC transporter of LPS O-antigen, Wzt lpp0838 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 54298451 Common - hypothetical protein lpp2515 5 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 54298490 Pathogen - hypothetical protein lpp2554 1 None None None 54296698 Common - hypothetical protein lpp0729 13 COG5572 COG5572, Predicted integral membrane protein Function unknown 54296100 Common - hypothetical protein lpp0119 48 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 54297119 Pathogen - hypothetical protein lpp1164 1 None None None 54298391 Pathogen - hypothetical protein lpp2455 1 None None None 54298826 Common glmS Glucosamine--fructose-6-phosphate aminotransferase lpp2893 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 54297199 Pathogen - hypothetical protein lpp1244 1 None None None 54297641 Common - hypothetical protein lpp1692 23 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54296109 Common gcsB glycine dehydrogenase subunit 2 lpp0128 174 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 54298702 Common pheS Phenylalanyl-tRNA synthetase, alpha subunit lpp2766 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 54296534 Common - hypothetical protein lpp0565 2 None None None 54297913 Common - hypothetical protein lpp1968 32 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 54298586 Common - hypothetical protein lpp2650 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 54298613 Common greA transcription elongation factor GreA lpp2677 204 COG0782 GreA, Transcription elongation factor Transcription 54298068 Common - hypothetical protein lpp2125 5 None None None 54295995 Common - hypothetical protein lpp0012 2 None None None 54297772 Pathogen - hypothetical protein lpp1823 1 None None None 54297833 Common - hypothetical protein lpp1885 113 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 54297901 Pathogen - hypothetical protein lpp1956 1 None None None 54297354 Common trpS tryptophanyl-tRNA synthetase lpp1399 227 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54296827 Common - hypothetical protein lpp0868 128 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 54297953 Common grpE Heat-shock protein GrpE(HSP-70 cofactor) lpp2008 230 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 54298100 Pathogen - hypothetical protein lpp2157 1 None None None 54296718 Common proS prolyl-tRNA synthetase lpp0749 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54298856 Common - hypothetical protein lpp2923 11 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 54296849 Common - hypothetical protein lpp0890 30 COG3672 COG3672, Predicted periplasmic protein Function unknown 54297091 Common - hypothetical protein lpp1136 9 COG1309 AcrR, Transcriptional regulator Transcription 54296344 Common - hypothetical protein lpp0373 189 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 54296079 Common - hypothetical protein lpp0097 19 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 54296774 Common iraA small-molecule methyltransferase IraA lpp0813 2 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 54297590 Common - hypothetical protein lpp1641 13 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 54298926 Common apaH diadenosine tetraphosphatase lpp2993 77 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 54297258 Common - hypothetical protein lpp1303 154 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 54297950 Common carA carbamoyl phosphate synthase small subunit lpp2005 237 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 54296758 Common - hypothetical protein lpp0797 2 None None None 54297117 Pathogen - hypothetical protein lpp1162 1 None None None 54296471 Common - hypothetical protein lpp0502 6 COG0500 SmtA, SAM-dependent methyltransferases Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54296544 Common serS seryl-tRNA synthetase lpp0575 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 54297502 Common rplI 50S ribosomal protein L9 lpp1547 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 54296960 Common - hypothetical protein lpp1001 50 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 54298870 Common corA putative cobalt/magnesium uptake transporter lpp2937 180 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 54297599 Common purL Phosphoribosylformylglycinamidine synthase II (FGAM synthase II) lpp1650 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 54296757 Common - hypothetical protein lpp0796 38 COG0628 PerM, Predicted permease General function prediction only 54297882 Common - hypothetical protein lpp1937 6 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 54298167 Common - hypothetical protein lpp2224 71 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 54296121 Pathogen - hypothetical protein lpp0140 1 None None None 54297422 Common ala hypothetical protein lpp1467 186 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 54298953 Common - hypothetical protein lpp3020 92 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 54296076 Pathogen - hypothetical protein lpp0094 1 None None None 54296133 Common pgk phosphoglycerate kinase lpp0152 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 54296998 Common - hypothetical protein lpp1039 167 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 54295992 Common - hypothetical protein lpp0009 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 54297606 Common - hypothetical protein lpp1657 42 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 54296562 Common sdhC succinate dehydrogenase, cytochrome b556 subunit lpp0593 52 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 54297973 Common - hypothetical protein lpp2028 97 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 54297966 Common - hypothetical protein lpp2021 64 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 54298554 Common - hypothetical protein lpp2618 123 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 54298558 Pathogen - hypothetical protein lpp2622 1 None None None 54298949 Common lpxA UDP-N-acetylglucosamine acyltransferase lpp3016 147 COG1043 LpxA, Acyl- acyl carrier protein 54296005 Common - hypothetical protein lpp0022 148 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 54297192 Common - hypothetical protein lpp1237 19 None None None 54298212 Pathogen - hypothetical protein lpp2270 1 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 54298994 Pathogen - hypothetical protein lpp3061 1 None None None 54297431 Common ppt hypoxanthine-guanine phosphoribosyltransferase lpp1476 158 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 54298733 Common - oligoribonuclease lpp2797 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 54296606 Common - hypothetical protein lpp0637 184 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 54297687 Common rir1 ribonucleotide-diphosphate reductase subunit alpha lpp1738 222 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 54296884 Common ccmH Cytochrome c-type biogenesis protein CcmH lpp0925 90 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 54296410 Common - hypothetical protein lpp0440 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 54297665 Pathogen - hypothetical protein lpp1716 1 None None None 54296622 Common - hypothetical protein lpp0653 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 54296459 Common - hypothetical protein lpp0490 51 COG3655 COG3655, Predicted transcriptional regulator Transcription 54297006 Pathogen - hypothetical protein lpp1047 1 None None None 54297373 Common - tRNA-dihydrouridine synthase A lpp1418 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 54298513 Common sdeD SdeD protein (substrate of the Dot/Icm system) lpp2577 2 None None None 54298919 Common - hypothetical protein lpp2986 14 COG5628 COG5628, Predicted acetyltransferase General function prediction only 54296863 Common - hypothetical protein lpp0904 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 54299005 Pathogen - hypothetical protein lpp3072 1 None None None 54298146 Common - hypothetical protein lpp2203 115 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 54297998 Common - hypothetical protein lpp2055 35 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54296480 Common icmP/dotM hypothetical protein lpp0511 11 None None None 54297776 Common lon hypothetical protein lpp1827 216 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 54296803 Common - hypothetical protein lpp0843 130 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 54297397 Common - hypothetical protein lpp1442 150 COG1522 Lrp, Transcriptional regulators Transcription 54297929 Common - hypothetical protein lpp1984 30 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 54298494 Common - hypothetical protein lpp2558 206 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 54297491 Common - hypothetical protein lpp1536 52 COG2938 COG2938, Uncharacterized conserved protein Function unknown 54297438 Pathogen - hypothetical protein lpp1483 1 None None None 54297254 Common nadD hypothetical protein lpp1299 170 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 54296572 Pathogen - hypothetical protein lpp0603 1 None None None 54298076 Common - hypothetical protein lpp2133 148 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 54296805 Common csrA global regulator CsrA lpp0845 81 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 54296061 Common - hypothetical protein lpp0079 120 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54298781 Common - hypothetical protein lpp2845 125 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 54296940 Common - hypothetical protein lpp0981 46 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 54298300 Common - phosphoribosylpyrophosphate synthetase lpp2358 243 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 54298719 Common ppiB Peptidyl-prolyl cis-trans isomerase B (cyclophilin-type PPIase family) lpp2783 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 54297655 Common - hypothetical protein lpp1706 5 COG4254 COG4254, Uncharacterized protein conserved in bacteria Function unknown 54298657 Common rpoH RNA polymerase factor sigma-32 lpp2721 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 54298112 Common - hypothetical protein lpp2169 20 None None None 54298648 Common feoA ferrous iron transporter A lpp2712 56 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 54297897 Common - hypothetical protein lpp1952 7 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 54298751 Common - hypothetical protein lpp2815 70 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 54296419 Common - hypothetical protein lpp0449 36 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 54298837 Common - hypothetical protein lpp2904 6 COG1647 COG1647, Esterase/lipase General function prediction only 54296978 Common - hypothetical protein lpp1019 2 None None None 54296112 Common gcvH hypothetical protein lpp0131 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 54298667 Common - hypothetical protein lpp2731 130 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 54298821 Common - hypothetical protein lpp2888 19 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 54296452 Common zwf glucose-6-phosphate 1-dehydrogenase lpp0483 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 54296311 Pathogen - hypothetical protein lpp0340 2 None None None 54297440 Common - hypothetical protein lpp1485 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 54296734 Common - hypothetical protein lpp0765 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 54296293 Common - hypothetical protein lpp0322 70 COG1738 COG1738, Uncharacterized conserved protein Function unknown 54296334 Common - hypothetical protein lpp0363 3 None None None 54296328 Common - hypothetical protein lpp0357 177 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 54296089 Common - hypothetical protein lpp0107 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 54296648 Common - hypothetical protein lpp0679 18 None None None 54297200 Common surE Acid phosphatase SurE (Stationary phase survival protein ) lpp1245 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 54297753 Common glyQ glycyl-tRNA synthetase subunit alpha lpp1804 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 54298050 Common - hypothetical protein lpp2107 22 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 54296025 Pathogen - hypothetical protein lpp0042 1 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 54298484 Common - hypothetical protein lpp2548 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 54296653 Common - hypothetical protein lpp0684 17 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 54297556 Common - hypothetical protein lpp1606 27 None None None 54297679 Common ftsK hypothetical protein lpp1730 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 54298673 Common dlpA DlpA protein (isocitrate and isopropylmalate dehydrogenase family protein) lpp2737 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 54296190 Pathogen - hypothetical protein lpp0216 1 None None None 54298242 Pathogen - hypothetical protein lpp2300 1 None None None 54296531 Common - hypothetical protein lpp0562 182 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 54298286 Common gdhA hypothetical protein lpp2344 175 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 54298254 Common - hypothetical protein lpp2312 62 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 54298761 Common nuoL NADH-quinone oxidoreductase chain L lpp2825 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 54297125 Common - hypothetical protein lpp1170 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 54297334 Common - hypothetical protein lpp1379 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 54297743 Common - acetyl-CoA synthetase lpp1794 204 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 54297781 Common - hypothetical protein lpp1832 26 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 54296921 Pathogen - hypothetical protein lpp0962 1 None None None 54298324 Common - hypothetical protein lpp2383 21 None None None 54298685 Common - hypothetical protein lpp2749 116 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 54297345 Common - hypothetical protein lpp1390 116 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 54296215 Pathogen - hypothetical protein lpp0241 1 None None None 54296879 Common ccmC heme exporter protein CcmC lpp0920 112 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 54298282 Pathogen - hypothetical protein lpp2340 1 None None None 54298804 Pathogen - hypothetical protein lpp2869 1 None None None 54296745 Common - hypothetical protein lpp0784 144 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 54297622 Common astB succinylarginine dihydrolase lpp1673 34 COG3724 AstB, Succinylarginine dihydrolase Amino acid transport and metabolism 54298377 Common - hypothetical protein lpp2441 123 COG0583 LysR, Transcriptional regulator Transcription 54297180 Common flgC flagellar basal body rod protein FlgC lpp1225 125 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 54296847 Common xseA Exonuclease VII, large subunit lpp0888 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 54298777 Common folP Dihydropteroate synthase lpp2841 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 54298249 Common rpsU 30S ribosomal protein S21 lpp2307 138 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 54298097 Common - hypothetical protein lpp2154 11 None None None 54298501 Common - hypothetical protein lpp2565 5 COG4095 COG4095, Uncharacterized conserved protein Function unknown 54297187 Common flgJ peptidoglycan hydrolase lpp1232 70 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 54296498 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein lpp0529 192 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 54297787 Common - hypothetical protein lpp1838 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 54297418 Common - hypothetical protein lpp1463 14 COG3725 AmpE, Membrane protein required for beta-lactamase induction Defense mechanisms 54297663 Common clpB endopeptidase Clp ATP-binding chain B (ClpB) lpp1714 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 54297563 Pathogen - hypothetical protein lpp1614 1 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 54296669 Common wrbA hypothetical protein lpp0700 111 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 54296032 Common - hypothetical protein lpp0049 10 COG3393 COG3393, Predicted acetyltransferase General function prediction only 54298626 Pathogen - hypothetical protein lpp2690 1 None None None 54298059 Common - hypothetical protein lpp2116 36 COG1396 HipB, Predicted transcriptional regulators Transcription 54296893 Pathogen - hypothetical protein lpp0934 1 None None None 54298319 Common - hypothetical protein lpp2378 3 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 54298036 Common - hypothetical protein lpp2093 2 None None None 54296465 Common - hypothetical protein lpp0496 109 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54298640 Common rplU 50S ribosomal protein L21 lpp2704 204 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 54298542 Common - hypothetical protein lpp2606 137 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 54297949 Common metK S-adenosylmethionine synthetase lpp2004 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 54296917 Common - hypothetical protein lpp0958 109 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 54298238 Common fadH hypothetical protein lpp2296 199 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 54296159 Pathogen - hypothetical protein lpp0182 1 None None None 54298794 Common - hypothetical protein lpp2858 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 54296492 Common citA/tphA proline/betaine transport protein homolog lpp0523 128 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54298763 Common nuoJ NADH-quinone oxidoreductase chain J lpp2827 115 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 54297629 Pathogen - hypothetical protein lpp1680 1 COG3678 CpxP, P pilus assembly/Cpx signaling pathway, periplasmic inhibitor/zinc-resistance associated protein Intracellular trafficking and secretion / Cell motility and secretio / Signal transduction mechanisms / Inorganic ion transport and metabolism 54297768 Common - hypothetical protein lpp1819 18 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 54298185 Common rluC Ribosomal large subunit pseudouridine synthase lpp2242 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 54297087 Pathogen - hypothetical protein lpp1132 1 None None None 54297133 Common - hypothetical protein lpp1178 24 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 54297268 Common lspJ type II secretory pathway protein LspJ lpp1313 31 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 54298744 Common - hypothetical protein lpp2808 203 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 54297849 Common - hypothetical protein lpp1901 5 None None None 54298817 Pathogen - hypothetical protein lpp2882 1 None None None 54297603 Pathogen - hypothetical protein lpp1654 1 None None None 54296551 Pathogen - hypothetical protein lpp0582 1 None None None 54298565 Pathogen - hypothetical protein lpp2629 1 None None None 54298156 Common - hypothetical protein lpp2213 5 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 54298895 Common coxB cytochrome c oxidase, subunit II lpp2962 163 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 54298400 Common - hypothetical protein lpp2464 23 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 54298015 Common tphB proline/glycine betaine transporter-like protein lpp2072 129 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54297043 Pathogen - hypothetical protein lpp1085 1 None None None 54298203 Common - hypothetical protein lpp2261 16 COG3930 COG3930, Uncharacterized protein conserved in bacteria Function unknown 54296870 Common - hypothetical protein lpp0911 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 54297272 Common lspF type II secretory pathway protein LspF lpp1317 149 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 54298690 Common - hypothetical protein lpp2754 202 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 54296227 Pathogen - hypothetical protein lpp0253 1 None None None 54298604 Common ftsW Cell division protein ftsW lpp2668 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 54296430 Pathogen - hypothetical protein lpp0461 1 None None None 54296586 Pathogen - hypothetical protein lpp0617 1 None None None 54297838 Common - hypothetical protein lpp1890 32 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 54296226 Common katG catalase-peroxidase lpp0252 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 54296928 Common flgM hypothetical protein lpp0969 6 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 54297570 Common iolD hypothetical protein lpp1621 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 54296905 Common - hypothetical protein lpp0946 176 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 54296039 Pathogen - hypothetical protein lpp0056 1 None None None 54297862 Common - hypothetical protein lpp1917 52 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 54298508 Pathogen - hypothetical protein lpp2572 1 None None None 54297069 Common - hypothetical protein lpp1114 176 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 54298635 Common gacA/letA Legionella transmission activator LetA lpp2699 224 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 54298965 Common - major outer membrane protein lpp3032 2 None None None 54298526 Common - hypothetical protein lpp2590 62 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 54298046 Pathogen - hypothetical protein lpp2103 1 None None None 54296868 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase lpp0909 220 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 54296160 Common - hypothetical protein lpp0183 137 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 54298124 Common - hypothetical protein lpp2181 213 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54298370 Common - hypothetical protein lpp2434 11 None None None 54297233 Common - hypothetical protein lpp1278 151 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54296688 Common - hypothetical protein lpp0719 139 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54297671 Common fliH Polar flagellar assembly protein FliH lpp1722 12 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 54298597 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase lpp2661 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 54297217 Pathogen - hypothetical protein lpp1262 2 None None None 54296205 Common - hypothetical protein lpp0231 35 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 54297270 Common lspH type II secretory pathway protein LspH lpp1315 3 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 54297627 Common tsf elongation factor Ts lpp1678 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 54297814 Common - hypothetical protein lpp1865 114 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 54298276 Common - F0F1 ATP synthase subunit alpha lpp2334 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 54298970 Common ahpC alkyl hydroperoxide reductase lpp3037 215 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 54297800 Common - hypothetical protein lpp1851 14 None None None 54298038 Common sdeB substrates of the Legionella pneumophila Dot/Icm system SdeB lpp2095 29 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 54296618 Pathogen - hypothetical protein lpp0649 1 None None None 54298406 Common - hypothetical protein lpp2470 9 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 54298261 Common - hypothetical protein lpp2319 2 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 54297165 Common - hypothetical protein lpp1210 134 COG1846 MarR, Transcriptional regulators Transcription 54298137 Common - hypothetical protein lpp2194 144 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 54296143 Common lvrA Legionella vir region protein lpp0166 5 None None None 54298120 Common - hypothetical protein lpp2177 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 54297246 Common fliS hypothetical protein lpp1291 86 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 54296058 Pathogen - hypothetical protein lpp0076 1 None None None 54297810 Common - hypothetical protein lpp1861 56 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 54296230 Pathogen - hypothetical protein lpp0256 1 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 54297241 Common - hypothetical protein lpp1286 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 54296453 Common pgl hypothetical protein lpp0484 117 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 54296244 Common - hypothetical protein lpp0271 142 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 54297941 Common - hypothetical protein lpp1996 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 54296346 Common - hypothetical protein lpp0375 120 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 54298216 Common radA DNA repair protein RadA lpp2274 205 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 54298993 Common atpI hypothetical protein lpp3060 37 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 54297601 Pathogen - hypothetical protein lpp1652 1 None None None 54296761 Common - hypothetical protein lpp0800 222 COG0171 NadE, NAD synthase Coenzyme metabolism 54297320 Common - hypothetical protein lpp1365 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 54298012 Pathogen - hypothetical protein lpp2069 1 None None None 54298567 Pathogen - hypothetical protein lpp2631 1 None None None 54297970 Common - hypothetical protein lpp2025 86 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 54297411 Pathogen - hypothetical protein lpp1456 1 None None None 54296281 Pathogen - hypothetical protein lpp0310 1 None None None 54296417 Common - hypothetical protein lpp0447 4 None None None 54297723 Common lysAC bifunctional aspartate kinase/diaminopimelate decarboxylase protein lpp1774 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 54298228 Common dksA hypothetical protein lpp2286 155 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 54297817 Common - hypothetical protein lpp1869 45 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 54297015 Common - hypothetical protein lpp1057 21 None None None 54296265 Common cyoA cytochrome o ubiquinol oxidase subunit II lpp0294 112 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 54296797 Common wzm ABC transporter of LPS O-antigen, Wzm lpp0837 114 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 54298193 Common aroC chorismate synthase lpp2251 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 54298779 Common rrmJ Ribosomal RNA large subunit methyltransferase (Cell division protein FtsJ) lpp2843 141 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 54297689 Pathogen - hypothetical protein lpp1740 1 None None None 54298687 Common miaA hypothetical protein lpp2751 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 54296721 Common - hypothetical protein lpp0752 184 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 54297933 Common - hypothetical protein lpp1988 49 COG3577 COG3577, Predicted aspartyl protease General function prediction only 54297449 Common - hypothetical protein lpp1494 116 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 54296405 Common - hypothetical protein lpp0434 84 COG0400 COG0400, Predicted esterase General function prediction only 54296790 Pathogen - hypothetical protein lpp0830 1 None None None 54297381 Common - hypothetical protein lpp1426 22 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 54297513 Common - hypothetical protein lpp1558 26 None None None 54296034 Common - hypothetical protein lpp0051 12 None None None 54297277 Pathogen - hypothetical protein lpp1322 1 None None None 54297005 Pathogen - hypothetical protein lpp1046 1 None None None 54297145 Common - hypothetical protein lpp1190 89 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 54298178 Common - hypothetical protein lpp2235 2 None None None 54296118 Common dsbA thiol:disulfide interchange protein precursor DsbA lpp0137 55 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 54297739 Common - hypothetical protein lpp1790 144 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 54297529 Common - hypothetical protein lpp1577 4 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 54297182 Common flgE flagellar hook protein FlgE lpp1227 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 54296391 Common rplQ 50S ribosomal protein L17 lpp0420 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 54298695 Common petB hypothetical protein lpp2759 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 54296197 Pathogen - hypothetical protein lpp0223 1 None None None 54296376 Common rplX 50S ribosomal protein L24 lpp0405 196 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 54297226 Common cysS cysteine tRNA synthetase lpp1271 242 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 54297295 Pathogen - hypothetical protein lpp1340 1 None None None 54297730 Common lpxK hypothetical protein lpp1781 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 54298909 Pathogen - hypothetical protein lpp2976 1 None None None 54298911 Common - hypothetical protein lpp2978 8 None None None 54297362 Pathogen - hypothetical protein lpp1407 1 None None None 54298697 Common rpsI 30S ribosomal protein S9 lpp2761 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 54296398 Common - hypothetical protein lpp0427 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 54297761 Common - hypothetical protein lpp1812 38 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 54298164 Common - hypothetical protein lpp2221 77 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 54297364 Pathogen - hypothetical protein lpp1409 1 None None None 54297189 Common flgL flagellar hook-associated protein FlgL lpp1234 98 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 54298413 Common - hypothetical protein lpp2477 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 54298939 Common - hypothetical protein lpp3006 42 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 54297194 Common - hypothetical protein lpp1239 115 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 54298028 Common - hypothetical protein lpp2085 39 COG5507 COG5507, Uncharacterized conserved protein Function unknown 54298171 Common - hypothetical protein lpp2228 157 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 54298375 Common - hypothetical protein lpp2439 10 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54297482 Common - hypothetical protein lpp1527 210 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 54298507 Common - hypothetical protein lpp2571 2 None None None 54296384 Common rplO 50S ribosomal protein L15 lpp0413 213 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 54297650 Common gatA Glutamyl-tRNA(Gln) amidotransferase (subunit A) lpp1701 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 54297075 Pathogen map Major acid phosphatase Map (histidine-acid phosphatase) lpp1120 2 None None None 54297631 Pathogen - hypothetical protein lpp1682 2 None None None 54298268 Pathogen - hypothetical protein lpp2326 1 COG1396 HipB, Predicted transcriptional regulators Transcription 54296002 Common - hypothetical protein lpp0019 41 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 54298700 Common himA hypothetical protein lpp2764 202 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 54296518 Common hflC membrane protease subunit HflC lpp0549 189 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 54297587 Common - hypothetical protein lpp1638 8 None None None 54297854 Pathogen - hypothetical protein lpp1909 1 None None None 54296840 Common - hypothetical protein lpp0881 14 None None None 54297981 Pathogen - hypothetical protein lpp2036 2 COG1577 ERG12, Mevalonate kinase Lipid metabolism 54298453 Common - hypothetical protein lpp2517 2 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 54298364 Pathogen - hypothetical protein lpp2427 1 None None None 54297388 Common - hypothetical protein lpp1433 80 COG2928 COG2928, Uncharacterized conserved protein Function unknown 54298106 Pathogen - hypothetical protein lpp2163 1 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 54298729 Common hemX hypothetical protein lpp2793 52 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 54296897 Common pnaB NAD(P) transhydrogenase subunit beta (Pyridine nucleotide transhydrogenase subunit alpha II) lpp0938 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 54298468 Common - hypothetical protein lpp2532 76 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 54297536 Common - hypothetical protein lpp1586 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 54296314 Common - hypothetical protein lpp0343 78 COG0433 COG0433, Predicted ATPase General function prediction only 54298579 Common parB hypothetical protein lpp2643 188 COG1475 Spo0J, Predicted transcriptional regulators Transcription 54297770 Common fabI hypothetical protein lpp1821 236 COG0623 FabI, Enoyl- acyl-carrier-protein 54296932 Common - pantothenate kinase lpp0973 137 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 54296523 Common - hypothetical protein lpp0554 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 54297926 Common secF preprotein translocase subunit SecF lpp1981 215 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 54298584 Common def hypothetical protein lpp2648 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 54298005 Common - hypothetical protein lpp2062 3 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 54296591 Common - hypothetical protein lpp0622 66 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 54297979 Common - isopentenyl pyrophosphate isomerase lpp2034 80 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 54297174 Common - hypothetical protein lpp1219 21 None None None 54296088 Common rnr/lidP hypothetical protein lpp0106 194 COG0557 VacB, Exoribonuclease R Transcription 54297500 Common - hypothetical protein lpp1545 61 None None None 54296532 Common gpmI phosphoglyceromutase lpp0563 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 54296712 Common groEL chaperonin GroEL lpp0743 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 54297057 Common - hypothetical protein lpp1102 19 None None None 54296135 Common tkt transketolase lpp0154 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 54298859 Pathogen - hypothetical protein lpp2926 1 None None None 54298198 Common secB preprotein translocase subunit SecB lpp2256 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 54296829 Common murG N-acetylglucosaminyl transferase lpp0870 204 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 54296986 Common - hypothetical protein lpp1027 8 None None None 54296786 Common gpi Glucose-6-phosphate isomerase lpp0825 198 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 54297878 Common - hypothetical protein lpp1933 95 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 54298529 Common - hypothetical protein lpp2593 10 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 54297706 Pathogen - hypothetical protein lpp1757 1 None None None 54298338 Pathogen - hypothetical protein lpp2397 1 None None None 54296126 Pathogen - hypothetical protein lpp0145 1 None None None 54296696 Common - hypothetical protein lpp0727 192 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 54298467 Common - hypothetical protein lpp2531 22 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 54296044 Common - hypothetical protein lpp0061 22 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 54298892 Common coxC cytochrome c oxidase, subunit III lpp2959 149 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 54297424 Common lssX Legionella secretion system protein X lpp1469 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 54297453 Common engA GTP-binding protein EngA lpp1498 231 COG1160 COG1160, Predicted GTPases General function prediction only 54297597 Common purQ Phosphoribosylformylglycinamidine synthase I (FGAM synthase I) lpp1648 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 54296706 Common - hypothetical protein lpp0737 32 None None None 54297405 Pathogen - hypothetical protein lpp1450 1 None None None 54297715 Pathogen - hypothetical protein lpp1766 1 None None None 54297696 Common fleN hypothetical protein lpp1747 238 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 54298612 Common - hypothetical protein lpp2676 32 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 54298141 Pathogen - hypothetical protein lpp2198 1 None None None 54298770 Common nuoC NADH dehydrogenase I chain C lpp2834 168 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 54297034 Common - hypothetical protein lpp1076 5 None None None 54297805 Common - hypothetical protein lpp1856 132 COG0657 Aes, Esterase/lipase Lipid metabolism 54298925 Common - hypothetical protein lpp2992 78 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54298861 Common lgt prolipoprotein diacylglyceryl transferase lpp2928 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 54296658 Common - hypothetical protein lpp0689 86 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 54296257 Common - hypothetical protein lpp0284 19 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 54298305 Common cebC Chemiosmotic efflux system B protein C lpp2363 53 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54296288 Pathogen - hypothetical protein lpp0317 1 None None None 54296321 Pathogen - hypothetical protein lpp0350 1 None None None 54298987 Common atpG F0F1 ATP synthase subunit gamma lpp3054 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 54298792 Common - hypothetical protein lpp2856 70 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 54296250 Common purE Phosphoribosylaminoimidazole carboxylase catalytic subunit lpp0277 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 54296511 Common rpoN RNA polymerase factor sigma-54 lpp0542 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 54298474 Common hypC Hydrogenase expression/formation protein HypC lpp2538 89 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 54298570 Common - hypothetical protein lpp2634 6 None None None 54297304 Common fabD Malonyl CoA-acyl carrier protein transacylase lpp1349 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 54296608 Pathogen - hypothetical protein lpp0639 1 None None None 54296182 Common - hypothetical protein lpp0207 52 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 54296352 Common secE preprotein translocase subunit SecE lpp0381 34 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 54298092 Pathogen - hypothetical protein lpp2149 1 None None None 54297315 Common - hypothetical protein lpp1360 142 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54297343 Common deoC hypothetical protein lpp1388 131 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 54297823 Pathogen - hypothetical protein lpp1875 1 None None None 54297092 Common - hypothetical protein lpp1137 35 None None None 54298061 Common - hypothetical protein lpp2118 7 None None None 54297919 Common - hypothetical protein lpp1974 19 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 54296366 Common rplD 50S ribosomal protein L4 lpp0395 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 54297843 Common - hypothetical protein lpp1895 94 COG2835 COG2835, Uncharacterized conserved protein Function unknown