Nocardia farcinica IFM 10152 plasmid pNF1, complete sequence NC_006362 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 54027761 Common - putative phosphoketolase pnf11130 62 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 54027655 Pathogen - hypothetical protein pnf170 1 None None None 54027768 Common - putative transcriptional regulator pnf11200 14 COG2188 PhnF, Transcriptional regulators Transcription 54027709 Common - putative copper oxidase pnf1600 112 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 54027697 Common - hypothetical protein pnf1480 36 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 54027792 Common - hypothetical protein pnf11440 2 None None None 54027799 Common - hypothetical protein pnf11510 4 None None None 54027750 Common - hypothetical protein pnf11020 44 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 54027712 Pathogen - putative DNA-binding protein pnf1630 1 None None None 54027777 Pathogen - hypothetical protein pnf11290 1 None None None 54027726 Pathogen - hypothetical protein pnf1780 1 None None None 54027700 Common - putative copper resistance protein pnf1510 37 COG2372 CopC, Uncharacterized protein, homolog of Cu resistance protein CopC General function prediction only 54027759 Pathogen - hypothetical protein pnf11110 1 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 54027731 Common - hypothetical protein pnf1830 45 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 54027746 Pathogen - hypothetical protein pnf1980 1 None None None 54027783 Common - hypothetical protein pnf11350 31 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 54027744 Common - hypothetical protein pnf1960 8 None None None 54027673 Common - putative transporter pnf1250 41 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54027664 Pathogen - hypothetical protein pnf1160 1 None None None 54027733 Common - putative cation-transporting ATPase pnf1850 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 54027752 Common - hypothetical protein pnf11040 2 None None None 54027714 Common - hypothetical protein pnf1650 2 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 54027651 Common - putative recombinase pnf130 16 None None None 54027657 Pathogen - hypothetical protein pnf190 1 None None None 54027766 Pathogen - hypothetical protein pnf11180 1 None None None 54027797 Pathogen - hypothetical protein pnf11490 1 None None None 54027695 Common - hypothetical protein pnf1460 119 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 54027806 Common - cytochrome P450 monooxygenase pnf11580 76 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 54027790 Common - hypothetical protein pnf11420 7 None None None 54027685 Common - putative DNA-binding protein pnf1370 14 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 54027801 Common - putative DNA-binding protein pnf11530 9 COG1476 COG1476, Predicted transcriptional regulators Transcription 54027707 Common - putative pyridoxal-phosphate dependent enzyme pnf1580 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 54027785 Pathogen - hypothetical protein pnf11370 1 None None None 54027748 Common - hypothetical protein pnf11000 2 None None None 54027775 Common - hypothetical protein pnf11270 3 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 54027728 Common - putative pyridoxal-phosphate dependent enzyme pnf1800 214 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 54027735 Common - putative ABC transporter ATP-binding protein pnf1870 248 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 54027675 Common - hypothetical protein pnf1270 23 None None None 54027666 Common - putative ATP-binding protein pnf1180 27 None None None 54027720 Pathogen - hypothetical protein pnf1720 1 None None None 54027688 Common - hypothetical protein pnf1400 60 COG3000 ERG3, Sterol desaturase Lipid metabolism 54027796 Pathogen - hypothetical protein pnf11480 1 None None None 54027692 Common - putative cation transporter pnf1440 172 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 54027717 Pathogen - hypothetical protein pnf1680 1 None None None 54027653 Common - hypothetical protein pnf150 2 None None None 54027773 Pathogen - hypothetical protein pnf11250 1 None None None 54027780 Pathogen - hypothetical protein pnf11320 1 None None None 54027703 Common - putative transporter pnf1540 186 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 54027787 Common - hypothetical protein pnf11390 12 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 54027722 Common - hypothetical protein pnf1740 11 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 54027729 Common - putative transporter pnf1810 47 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54027749 Common - hypothetical protein pnf11010 2 None None None 54027705 Pathogen - hypothetical protein pnf1560 1 None None None 54027754 Pathogen - hypothetical protein pnf11060 1 None None None 54027690 Common - hypothetical protein pnf1420 57 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 54027794 Pathogen - hypothetical protein pnf11460 1 None None None 54027771 Pathogen - hypothetical protein pnf11230 1 None None None 54027671 Common - putative multicopper oxidase pnf1230 124 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 54027686 Common - hypothetical protein pnf1380 17 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 54027678 Common - hypothetical protein pnf1300 14 COG3462 COG3462, Predicted membrane protein Function unknown 54027737 Common - hypothetical protein pnf1890 11 None None None 54027699 Common - hypothetical protein pnf1500 22 COG3336 COG3336, Predicted membrane protein Function unknown 54027719 Common - putative monooxygenase pnf1700 81 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 54027681 Common - putative cation-transporting ATPase pnf1330 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 54027763 Common - hypothetical protein pnf11150 12 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 54027805 Common - hypothetical protein pnf11570 3 None None None 54027710 Common - putative metal cation transporter pnf1610 46 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 54027803 Common - hypothetical protein pnf11550 4 None None None 54027701 Common - hypothetical protein pnf1520 10 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 54027659 Pathogen - hypothetical protein pnf1110 1 None None None 54027660 Pathogen - hypothetical protein pnf1120 1 None None None 54027782 Pathogen - hypothetical protein pnf11340 1 None None None 54027669 Common - putative resolvase pnf1210 115 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 54027662 Pathogen - hypothetical protein pnf1140 1 None None None 54027739 Common - hypothetical protein pnf1910 10 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 54027758 Common - hypothetical protein pnf11100 4 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 54027730 Common - hypothetical protein pnf1820 45 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 54027756 Common - hypothetical protein pnf11080 33 COG4646 COG4646, DNA methylase Transcription / DNA replication, recombination, and repair 54027724 Common - hypothetical protein pnf1760 4 None None None 54027696 Common - putative peptidase pnf1470 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 54027742 Pathogen - hypothetical protein pnf1940 1 None None None 54027711 Common - putative iron sulphur protein pnf1620 52 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 54027778 Pathogen - hypothetical protein pnf11300 1 None None None 54027747 Common - hypothetical protein pnf1990 5 None None None 54027725 Common - putative multicopper oxidase pnf1770 127 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 54027665 Common - putative integrase pnf1170 58 None None None 54027674 Common - hypothetical protein pnf1260 37 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 54027789 Common - hypothetical protein pnf11410 8 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 54027687 Common - hypothetical protein pnf1390 3 None None None 54027767 Pathogen - hypothetical protein pnf11190 1 None None None 54027713 Common - hypothetical protein pnf1640 2 None None None 54027804 Common - hypothetical protein pnf11560 5 None None None 54027760 Common - putative methyltransferase pnf11120 31 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 54027679 Common - hypothetical protein pnf1310 39 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 54027798 Common - hypothetical protein pnf11500 100 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 54027807 Common - hypothetical protein pnf11590 11 None None None 54027694 Common - putative thioredoxin pnf1450 112 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 54027684 Common - putative transporter pnf1360 13 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 54027791 Common - hypothetical protein pnf11430 4 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 54027740 Pathogen - hypothetical protein pnf1920 1 None None None 54027727 Pathogen - hypothetical protein pnf1790 1 None None None 54027708 Common - putative transporter pnf1590 56 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 54027676 Common - putative cation-transporting ATPase pnf1280 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 54027776 Pathogen - hypothetical protein pnf11280 1 None None None 54027732 Common - hypothetical protein pnf1840 21 None None None 54027784 Common - hypothetical protein pnf11360 40 COG0714 COG0714, MoxR-like ATPases General function prediction only 54027667 Common - hypothetical protein pnf1190 5 None None None 54027734 Pathogen - hypothetical protein pnf1860 1 None None None 54027654 Pathogen - hypothetical protein pnf160 1 None None None 54027765 Common - hypothetical protein pnf11170 68 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 54027774 Pathogen - hypothetical protein pnf11260 1 None None None 54027715 Common - putative recombinase pnf1660 7 None None None 54027800 Common - hypothetical protein pnf11520 16 None None None 54027682 Common - putative signal peptidase pnf1340 19 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 54027751 Pathogen - hypothetical protein pnf11030 1 None None None 54027668 Common - hypothetical protein pnf1200 5 None None None 54027683 Common - putative transporter pnf1350 175 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 54027736 Common - putative ABC transporter membrane protein pnf1880 4 None None None 54027808 Pathogen - hypothetical protein pnf11600 1 None None None 54027704 Common - putative esterase pnf1550 13 COG0627 COG0627, Predicted esterase General function prediction only 54027716 Common - hypothetical protein pnf1670 7 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 54027721 Pathogen - putative regulator pnf1730 1 None None None 54027741 Pathogen - hypothetical protein pnf1930 1 None None None 54027698 Common - hypothetical protein pnf1490 13 None None None 54027755 Pathogen - hypothetical protein pnf11070 1 None None None 54027706 Common - putative cation transporter pnf1570 205 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 54027786 Common - hypothetical protein pnf11380 5 None None None 54027757 Common - putative methyltransferase pnf11090 57 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 54027718 Common - hypothetical protein pnf1690 2 None None None 54027656 Pathogen - hypothetical protein pnf180 1 None None None 54027650 Common parB putative plasmid partitioning protein pnf120 156 COG1475 Spo0J, Predicted transcriptional regulators Transcription 54027689 Common - hypothetical protein pnf1410 18 None None None 54027772 Pathogen - hypothetical protein pnf11240 1 None None None 54027693 Common - hypothetical protein pnf1445 79 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 54027753 Common - hypothetical protein pnf11050 17 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 54027677 Common - hypothetical protein pnf1290 2 COG2962 RarD, Predicted permeases General function prediction only 54027680 Common - putative transcriptional regulator pnf1320 91 COG0640 ArsR, Predicted transcriptional regulators Transcription 54027795 Pathogen - hypothetical protein pnf11470 1 None None None 54027764 Common - putative hydrolase pnf11160 26 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 54027702 Common - hypothetical protein pnf1530 23 COG3682 COG3682, Predicted transcriptional regulator Transcription 54027788 Pathogen - hypothetical protein pnf11400 1 None None None 54027661 Common - hypothetical protein pnf1130 2 None None None 54027658 Common - hypothetical protein pnf1100 24 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 54027745 Common - hypothetical protein pnf1970 6 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 54027743 Common - putative recombinase pnf1950 189 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 54027663 Pathogen - hypothetical protein pnf1150 2 None None None 54027723 Pathogen - hypothetical protein pnf1750 1 None None None 54027691 Common - hypothetical protein pnf1430 20 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 54027672 Common - putative pyridoxal-phosphate dependent enzyme pnf1240 213 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 54027770 Pathogen - hypothetical protein pnf11220 1 None None None 54027793 Common - hypothetical protein pnf11450 4 None None None 54027670 Common - hypothetical protein pnf1220 2 None None None 54027738 Common - hypothetical protein pnf1900 11 None None None 54027781 Pathogen - hypothetical protein pnf11330 1 None None None 54027652 Common - putative recombinase pnf140 45 None None None 54027649 Common parA putative plasmid partitioning protein pnf110 22 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 54027802 Common - hypothetical protein pnf11540 2 None None None 54027769 Common - putative orotidine 5'-phosphate decarboxylase pnf11210 151 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 54027779 Common - putative DNA-binding protein pnf11310 6 COG1395 COG1395, Predicted transcriptional regulator Transcription 54027762 Pathogen - hypothetical protein pnf11140 1 None None None