Bartonella quintana str. Toulouse, complete genome NC_005955 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 49473933 Common aldA Aldehyde dehydrogenase BQ02840 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 49474723 Common - ABC transporter, ATP-binding protein BQ12380 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 49474202 Common prfB peptide chain release factor 2 BQ05900 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 49474416 Common - hypothetical protein BQ08360 3 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 49474261 Common recJ Single-stranded-DNA-specific exonuclease BQ06620 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 49473936 Common - hypothetical protein BQ02870 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 49474618 Common - hypothetical protein BQ11070 2 None None None 49473942 Common pgl 6-phosphogluconolactonase BQ02940 115 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 49474156 Common - hypothetical protein BQ05360 8 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 49473788 Common dnaA chromosomal replication initiation protein BQ01110 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 49474741 Pathogen trwL8 trwL8 protein BQ12560 1 None None None 49474174 Common folE GTP cyclohydrolase I BQ05540 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 49474139 Common clpP ATP-dependent Clp protease proteolytic subunit BQ05040 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 49474046 Common thiG thiazole synthase BQ04080 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 49474556 Common - hypothetical protein BQ10180 11 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 49474375 Common alaS alanyl-tRNA synthetase BQ07940 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49474798 Common xerD Integrase /recombinase xerD BQ13260 229 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 49473832 Common - Polysialic acid capsule expression protein BQ01650 163 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 49474458 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase BQ08880 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 49474629 Common maf-2 Septum formation maf protein BQ11190 184 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 49474420 Common - hypothetical protein BQ08440 6 None None None 49474272 Common gltX glutamyl-tRNA synthetase BQ06770 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 49474770 Common - hypothetical protein BQ12880 44 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 49474194 Common lolC Lipoprotein releasing system transmembrane protein lolC BQ05810 226 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 49474131 Common lipA lipoyl synthase BQ04950 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 49473973 Common pth peptidyl-tRNA hydrolase BQ03280 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 49473689 Common - hypothetical protein BQ00010 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 49473909 Common - hypothetical protein BQ02470 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 49474451 Common ftsA Cell division protein ftsA BQ08810 183 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 49473825 Common - hypothetical protein BQ01570 52 COG1872 COG1872, Uncharacterized conserved protein Function unknown 49474013 Common mutY A/G-specific adenine glycosylase BQ03730 237 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 49474604 Common - hypothetical protein BQ10850 5 None None None 49474548 Common fpr Ferredoxin-NADP reductase BQ10090 107 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 49473901 Common rnd1 Ribonuclease d BQ02390 104 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 49474050 Common hmuV hmuV protein BQ04120 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 49474130 Common pdhD2 dihydrolipoamide dehydrogenase BQ04940 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 49473727 Common infC translation initiation factor IF-3 BQ00430 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 49474483 Common carB carbamoyl phosphate synthase large subunit BQ09240 233 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 49473757 Common nth Endonuclease III BQ00740 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 49474527 Common - hypothetical protein BQ09730 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 49474287 Common lpxA UDP-N-acetylglucosamine acyltransferase BQ06920 165 COG1043 LpxA, Acyl- acyl carrier protein 49474702 Common - transcriptional factor regulator BQ12150 83 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 49473775 Common secB preprotein translocase subunit SecB BQ00950 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 49474622 Common - hypothetical protein BQ11110 8 None None None 49474704 Common ispA Geranyltranstransferase (farnesyl-diphosphate synthase) BQ12170 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 49474422 Pathogen - hypothetical protein BQ08460 1 None None None 49473791 Common aroQ 3-dehydroquinate dehydratase BQ01140 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 49474804 Common phaF putative monovalent cation/H+ antiporter subunit F BQ13320 52 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 49474460 Common murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6- diaminopimelate-D-alanyl-D-alanine ligase BQ08900 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 49474280 Common gltA type II citrate synthase BQ06850 194 COG0372 GltA, Citrate synthase Energy production and conversion 49473734 Common grpE Heat shock protein (hsp-70 cofactor) grpE BQ00500 233 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 49474817 Common mdh malate dehydrogenase BQ13450 177 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 49474165 Common - hypothetical protein BQ05450 25 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 49473712 Common - Chlorosome protein BQ00270 200 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 49474541 Common - Transcriptional regulator BQ10010 84 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 49474488 Common trkH trk system potassium uptake protein trkH BQ09290 126 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 49473781 Common dsbE Thiol 3A-disulfide interchange protein BQ01040 148 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 49474672 Common tolA tolA protein BQ11830 12 None None None 49474335 Common - hypothetical protein BQ07480 83 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 49473946 Common gshA Glutamate-cysteine ligase BQ02990 54 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 49474036 Common - Two-component response regulator BQ03980 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 49474727 Common - Outer membrane lipoprotein carrier protein BQ12420 34 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 49473994 Common fabI2 enoyl-(acyl carrier protein) reductase BQ03500 223 COG0623 FabI, Enoyl- acyl-carrier-protein 49473798 Common fabB 3-oxoacyl-(acyl carrier protein) synthase I BQ01210 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 49474500 Common - hypothetical protein BQ09410 189 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 49474142 Common hupB DNA-binding protein BQ05070 212 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 49473694 Common polA DNA polymerase I BQ00060 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 49474469 Common pncA Pyrazinamidase /nicotinamidase pnca BQ09020 118 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 49474109 Common - hypothetical protein BQ04720 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 49474539 Pathogen - hypothetical protein BQ09920 1 None None None 49474108 Common uvrC excinuclease ABC subunit C BQ04710 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 49474080 Common - Oxidoreductase BQ04420 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 49474004 Common rnhA Ribonuclease HI BQ03620 176 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 49474213 Pathogen - hypothetical protein BQ06010 1 None None None 49474574 Common - hypothetical protein BQ10480 80 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 49473774 Common maeB malic enzyme BQ00940 216 COG0281 SfcA, Malic enzyme Energy production and conversion 49474154 Common hfq RNA-binding protein Hfq BQ05340 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 49474475 Common - Outer membrane protein BQ09140 100 COG2968 COG2968, Uncharacterized conserved protein Function unknown 49474540 Common - hypothetical protein BQ09930 5 None None None 49474652 Pathogen - hypothetical protein BQ11520 1 None None None 49474718 Common - hypothetical protein BQ12320 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 49474631 Common - hypothetical protein BQ11210 18 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 49474673 Common tolR tolR protein BQ11840 127 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 49474756 Common sdhD Succinate dehydrogenase hydrophobic membrane anchor protein BQ12710 42 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 49474812 Common pdhD1 dihydrolipoamide dehydrogenase BQ13400 246 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 49474663 Pathogen - hypothetical protein BQ11720 3 COG4575 ElaB, Uncharacterized conserved protein Function unknown 49474122 Common pyrG CTP synthetase BQ04860 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 49473900 Common - hypothetical protein BQ02380 129 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 49473855 Common - Peptidyl-prolyl cis-trans isomerase BQ01880 159 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 49473967 Common - hypothetical protein BQ03210 37 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 49474685 Common - ABC transporter, ATP-binding protein BQ11960 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 49473911 Pathogen - hypothetical protein BQ02490 2 None None None 49474228 Common map methionine aminopeptidase BQ06230 246 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 49473957 Common engA GTP-binding protein EngA BQ03110 232 COG1160 COG1160, Predicted GTPases General function prediction only 49474515 Common - ABC transporter, periplasmic oligopeptide-binding protein BQ09580 195 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 49473726 Common msbA ABC transporter, ATP-binding protein BQ00420 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 49474360 Common glpX fructose 1,6-bisphosphatase II BQ07740 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 49474242 Common - Acyl-CoA dehydrogenase BQ06370 63 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 49474575 Pathogen - hypothetical protein BQ10500 1 None None None 49473876 Common - Transcriptional regulator BQ02090 42 COG1396 HipB, Predicted transcriptional regulators Transcription 49474403 Common rplD 50S ribosomal protein L4 BQ08220 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 49474309 Common rplJ 50S ribosomal protein L10 BQ07150 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 49474083 Common radA DNA repair protein RadA BQ04450 214 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 49474468 Pathogen - hypothetical protein BQ09010 1 None None None 49473701 Common - hypothetical protein BQ00140 14 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 49474090 Common fabD acyl-carrier-protein S-malonyltransferase BQ04520 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 49474560 Common - hypothetical protein BQ10260 74 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 49474113 Common serS seryl-tRNA synthetase BQ04770 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 49474769 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase BQ12870 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 49474026 Common - hypothetical protein BQ03880 18 COG5402 COG5402, Uncharacterized conserved protein Function unknown 49474267 Common - Amino acid permease BQ06710 144 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 49474399 Common rplV 50S ribosomal protein L22 BQ08180 215 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 49474730 Common hvrA Trans-acting regulatory protein hvrA BQ12450 17 COG2916 Hns, DNA-binding protein H-NS General function prediction only 49474070 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase BQ04320 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 49473811 Common badA2 Surface protein/Bartonella adhesin BQ01400 21 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 49473765 Common yfeD Iron transport system membrane protein yfeD BQ00820 189 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 49474187 Common nuoK NADH dehydrogenase subunit K BQ05740 80 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 49473769 Common rpsA 30S ribosomal protein S1 BQ00860 215 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 49473748 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase BQ00650 137 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 49474392 Common rplE 50S ribosomal protein L5 BQ08110 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 49473844 Common - ABC transporter, periplasmic binding protein BQ01770 175 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 49474315 Common - tRNA /rRNA methyltransferase BQ07240 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 49474058 Common smpB SsrA-binding protein BQ04200 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 49474068 Common recO DNA repair protein RecO BQ04300 88 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 49474381 Common rpsK 30S ribosomal protein S11 BQ08000 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 49473893 Common - ABC transporter permease protein BQ02310 223 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 49473890 Common moeB molybdopterin biosynthesis protein MoeB BQ02280 220 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 49474588 Common traG Conjugal transfer protein traG BQ10640 66 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 49474345 Common ppk polyphosphate kinase BQ07590 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 49474683 Common efp elongation factor P BQ11940 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 49474196 Common - hypothetical protein BQ05830 37 COG2938 COG2938, Uncharacterized conserved protein Function unknown 49474387 Common rpsE 30S ribosomal protein S5 BQ08060 245 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 49474143 Common - Response regulator BQ05210 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 49473862 Common hslV ATP-dependent protease peptidase subunit BQ01950 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 49473962 Common atpF2 F0F1 ATP synthase subunit B BQ03160 22 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 49474061 Common spoT GTP pyrophosphokinase BQ04230 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 49474302 Common dacA2 Penicillin-binding protein BQ07070 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 49474479 Common - hypothetical protein BQ09200 9 COG2261 COG2261, Predicted membrane protein Function unknown 49474293 Common frr ribosome recycling factor BQ06980 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 49473820 Common filA Filament-A percursor BQ01520 133 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 49473927 Pathogen - hypothetical protein BQ02730 1 None None None 49473950 Common grxC Glutaredoxin BQ03040 124 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 49474047 Common thiG1 thiamine biosynthesis protein ThiS BQ04090 14 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 49473926 Common - Biotin synthase BQ02720 8 COG1268 BioY, Uncharacterized conserved protein General function prediction only 49474728 Common ftsK Cell division protein ftsK BQ12430 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 49474421 Common - hypothetical protein BQ08450 140 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 49474356 Common argS arginyl-tRNA synthetase BQ07700 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49473996 Common ribA GTP cyclohydrolase II BQ03520 226 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 49474493 Common - RNA methyltransferase BQ09340 161 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 49474180 Common nuoD NADH dehydrogenase subunit D BQ05670 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 49474417 Common - Outer membrane protein BQ08370 144 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 49473780 Common - hypothetical protein BQ01020 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 49473713 Common - Sensor histidine kinase protein BQ00280 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 49474665 Common mrsA Phosphoglucomutase /phosphomannomutasefamily protein mrsA BQ11740 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 49474059 Common - hypothetical protein BQ04210 66 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 49474449 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase BQ08790 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 49473974 Common rplY 50S ribosomal protein L25/general stress protein Ctc BQ03290 185 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 49474051 Common hutC Hemin ABC transporter, permease protein BQ04130 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 49474262 Common rplM 50S ribosomal protein L13 BQ06630 229 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 49474620 Common - hypothetical protein BQ11090 5 None None None 49474591 Common - hypothetical protein BQ10670 2 None None None 49474557 Common nodN Nodulation protein n BQ10220 82 COG2030 MaoC, Acyl dehydratase Lipid metabolism 49474060 Common rpoZ DNA-directed RNA polymerase subunit omega BQ04220 115 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 49473764 Common yfeC Iron transport system membrane protein yfeC BQ00810 178 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 49473802 Common rpsU 30S ribosomal protein S21 BQ01250 39 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 49473695 Common - hypothetical protein BQ00070 67 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 49474155 Common hflX GTP-binding protein hflX BQ05350 222 COG2262 HflX, GTPases General function prediction only 49474123 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase BQ04870 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 49474141 Common lon1 ATP-dependent protease lon BQ05060 220 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 49474617 Common - 35 kDa protein homolog BQ11060 37 COG4675 MdpB, Microcystin-dependent protein Function unknown 49473952 Common lysC aspartate kinase BQ03060 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 49474797 Common accA acetyl-CoA carboxylase carboxyltransferase subunit alpha BQ13250 178 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 49474803 Common phaG putative monovalent cation/H+ antiporter subunit G BQ13310 12 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 49474203 Common bcp Bacterioferritin comigratory protein BQ05910 210 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 49474223 Common lexA LexA repressor BQ06160 164 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 49473934 Common - Cell division transmembrane protein BQ02850 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 49474512 Common - ABC transporter, permease protein BQ09550 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 49474820 Common dapF Diaminopimelate epimerase BQ13480 186 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 49473902 Pathogen - hypothetical protein BQ02400 1 None None None 49473945 Common - hypothetical protein BQ02980 160 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 49473870 Common infB translation initiation factor IF-2 BQ02030 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 49474595 Common - hypothetical protein BQ10710 26 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 49474671 Common tolB translocation protein TolB BQ11820 147 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 49474425 Common - hypothetical protein BQ08500 54 COG0392 COG0392, Predicted integral membrane protein Function unknown 49474699 Common rpoH2 RNA polymerase factor sigma-32 BQ12120 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 49473941 Common zwf glucose-6-phosphate 1-dehydrogenase BQ02930 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 49474473 Pathogen - phage related protein BQ09070 1 None None None 49473993 Common dnaJ2 Heat shock protein DnaJ BQ03490 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 49474241 Common - hypothetical protein BQ06360 165 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 49473799 Common fabA 3-hydroxydecanoyl-(acyl carrier protein) dehydratase BQ01220 80 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 49473884 Common recR recombination protein RecR BQ02180 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 49474170 Common - hypothetical protein BQ05500 92 COG0789 SoxR, Predicted transcriptional regulators Transcription 49474027 Common mrcA1 Penicillin-binding protein mrcA BQ03890 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 49474107 Common pgsA CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase BQ04700 204 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 49474063 Common - hypothetical protein BQ04250 26 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 49474164 Common nusB transcription antitermination protein NusB BQ05440 179 COG0781 NusB, Transcription termination factor Transcription 49474175 Common - hypothetical protein BQ05560 26 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 49474784 Common - Two-component response regulator BQ13040 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 49474790 Common tyrC cyclohexadienyl dehydrogenase BQ13130 167 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 49473754 Common - hypothetical protein BQ00710 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 49474081 Common purF amidophosphoribosyltransferase BQ04430 239 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 49474796 Common - hypothetical protein BQ13240 51 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 49474524 Common proC pyrroline-5-carboxylate reductase BQ09700 41 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 49474249 Common rpmG 50S ribosomal protein L33 BQ06440 124 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 49474326 Common purN Phosphoribosylglycinamide formyltransferase BQ07390 224 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 49474703 Common rpmF 50S ribosomal protein L32 BQ12160 109 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 49474691 Common - hypothetical protein BQ12030 11 None None None 49474749 Pathogen trwH2 hypothetical protein BQ12640 1 None None None 49474641 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase BQ11390 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 49473733 Common hrcA heat-inducible transcription repressor BQ00490 150 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 49474825 Common parB Chromosome partitioning protein, parb BQ13530 182 COG1475 Spo0J, Predicted transcriptional regulators Transcription 49474806 Common phaD putative monovalent cation/H+ antiporter subunit D BQ13340 209 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 49474404 Common rplC 50S ribosomal protein L3 BQ08230 217 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 49474197 Common mfd Transcription repair coupling factor BQ05840 215 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 49474684 Common suhB Extragenic suppressor protein suhb BQ11950 214 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 49474783 Common - hypothetical protein BQ13020 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 49473702 Common - hypothetical protein BQ00150 30 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 49473696 Common - hypothetical protein BQ00080 143 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 49474082 Common cvpA Colicin v production protein BQ04440 77 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 49474818 Common - hypothetical protein BQ13460 94 COG1485 COG1485, Predicted ATPase General function prediction only 49474659 Common - hypothetical protein BQ11660 24 COG1633 COG1633, Uncharacterized conserved protein Function unknown 49474091 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase BQ04530 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 49473875 Common metK S-adenosylmethionine synthetase BQ02080 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 49474098 Common - hypothetical protein BQ04600 70 None None None 49474220 Common tmk Thymidylate kinase BQ06110 226 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 49474482 Common - Probable transporter BQ09230 156 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 49474561 Common - hypothetical protein BQ10280 11 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 49474114 Common pcm protein-L-isoaspartate O-methyltransferase BQ04780 146 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 49473819 Common nadD nicotinic acid mononucleotide adenyltransferase BQ01490 137 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 49473740 Common - Transcriptional regulator BQ00560 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 49473948 Common - hypothetical protein BQ03020 66 None None None 49473833 Common - Outer membrane lipoprotein precursor BQ01660 7 None None None 49473925 Common - hypothetical protein BQ02710 63 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 49473783 Common ccmC Heme exporter protein C BQ01060 126 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 49474467 Common - putative ABC transporter ATP-binding protein BQ09000 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 49474020 Common - Transcriptional regulatory protein, ros/mucR family BQ03800 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 49473856 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein BQ01890 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 49474686 Common rpmE 50S ribosomal protein L31 BQ11970 126 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 49474692 Common - hypothetical protein BQ12040 29 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 49473912 Common pmbA pmbA protein, maturation of antibiotic mccb17 BQ02510 159 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 49474568 Common - hypothetical protein BQ10380 12 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 49474388 Common rplR 50S ribosomal protein L18 BQ08070 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 49473801 Common - hypothetical protein BQ01240 46 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 49474627 Common clpB ATP-dependent clp protease, ATP-binding subunit clpB BQ11170 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 49473772 Common - hypothetical protein BQ00890 17 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 49473826 Common ppa inorganic pyrophosphatase BQ01580 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 49474263 Common rpsI 30S ribosomal protein S9 BQ06640 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 49473961 Common atpF1 F0F1 ATP synthase subunit B' BQ03150 96 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 49473989 Common - hypothetical protein BQ03450 7 None None None 49474434 Common hflK Protease subunit hflK BQ08610 197 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 49473768 Common - Cyclic beta 1-2 glucan synthetase BQ00850 46 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 49473863 Common hslU ATP-dependent protease ATP-binding subunit BQ01960 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 49474474 Pathogen - hypothetical protein BQ09100 1 None None None 49474006 Common - hypothetical protein BQ03650 177 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 49474005 Common - hypothetical protein BQ03640 127 COG1678 COG1678, Putative transcriptional regulator Transcription 49474235 Common livH Branched chain amino acid ABC transporter, permease protein BQ06300 153 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 49474303 Common - hypothetical protein BQ07080 2 None None None 49474153 Common - hypothetical protein BQ05330 124 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 49474724 Common - hypothetical protein BQ12390 172 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 49474478 Common - hypothetical protein BQ09180 107 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 49473749 Common - hypothetical protein BQ00660 107 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 49474717 Common leuS leucyl-tRNA synthetase BQ12310 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49474264 Common divK Response regulator BQ06650 224 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 49474188 Common nuoL NADH dehydrogenase subunit L BQ05750 206 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 49474014 Common - hypothetical protein BQ03740 14 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 49473777 Common - hypothetical protein BQ00970 42 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 49474666 Common ftsH Cell division protein ftsH BQ11750 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 49474503 Common - hypothetical protein BQ09450 14 None None None 49474459 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase BQ08890 216 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 49474338 Common - hypothetical protein BQ07510 77 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 49474492 Common uvrB excinuclease ABC subunit B BQ09330 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 49474601 Common - hypothetical protein BQ10800 108 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 49474634 Common purK Phosphoribosylaminoimidazole carboxylase II BQ11290 192 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 49474215 Common pcsA Phosphatidylcholine synthase BQ06040 25 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 49474357 Common - hypothetical protein BQ07710 14 None None None 49474212 Pathogen - hypothetical protein BQ06000 2 None None None 49474344 Common - Exopolyphosphatase BQ07580 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 49474367 Common ssb Single-strand binding protein (ssb) BQ07860 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 49473818 Common proA Gamma-glutamyl phosphate reductase BQ01480 189 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 49474314 Common tuf elongation factor Tu BQ07210 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 49474401 Common rplB 50S ribosomal protein L2 BQ08200 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 49474619 Pathogen - hypothetical protein BQ11080 1 None None None 49474028 Common - hypothetical protein BQ03900 4 None None None 49474144 Common - Lysophospholipase l2 BQ05220 16 COG2267 PldB, Lysophospholipase Lipid metabolism 49474497 Common - hypothetical protein BQ09380 31 None None None 49474397 Common rplP 50S ribosomal protein L16 BQ08160 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 49474390 Common rpsH 30S ribosomal protein S8 BQ08090 248 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 49474795 Common dacA3 Penicillin-binding protein BQ13220 157 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 49474462 Common ftsI Penicillin-binding protein BQ08920 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 49474282 Common - ABC transporter, permease protein BQ06870 175 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 49473744 Common dnaJ1 Heat shock protein DnaJ BQ00600 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 49473886 Common dnaX DNA polymerase III subunits gamma and tau BQ02200 246 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 49474826 Common parA Chromosome partitioning protein para BQ13540 209 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 49474513 Common - ABC transporter permease protein BQ09560 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 49473729 Common - hypothetical protein BQ00450 154 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 49474366 Common gyrA DNA gyrase subunit A BQ07850 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 49474642 Common - phage related protein BQ11400 15 None None None 49473736 Common ptsH Phosphocarrier protein BQ00520 141 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 49474494 Common pcnB Poly(A) polymerase BQ09350 205 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 49474320 Common tig trigger factor BQ07290 214 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 49473721 Common gyrB DNA gyrase subunit B BQ00370 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 49474520 Pathogen - hypothetical protein BQ09660 1 None None None 49474633 Common purE Phosphoribosylaminoimidazole carboxylase I BQ11280 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 49474649 Common - hypothetical protein BQ11490 12 None None None 49474609 Common - two-component response regulator BQ10980 108 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 49474359 Common ilvE branched-chain amino acid aminotransferase BQ07730 207 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 49474439 Common - hypothetical protein BQ08680 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 49473692 Common coaE Dephospho-CoA kinase BQ00040 211 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 49474709 Common atpC ATP synthase epsilon chain BQ12220 50 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 49473944 Common - hypothetical protein BQ02970 17 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 49473852 Common prfA peptide chain release factor 1 BQ01850 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 49474002 Common cyoE protoheme IX farnesyltransferase BQ03590 166 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 49474124 Common eno Enolase BQ04880 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 49474125 Common - hypothetical protein BQ04890 5 COG2314 XynA, Predicted membrane protein Function unknown 49473940 Common - Oxidoreductase BQ02920 122 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 49474668 Common pal Peptidoglycan-associated lipoprotein BQ11770 154 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 49474590 Pathogen - hypothetical protein BQ10660 1 None None None 49474554 Common - hypothetical protein BQ10150 88 COG2835 COG2835, Uncharacterized conserved protein Function unknown 49474565 Common fatC Ferric anguibactin transport system permease protein BQ10320 41 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 49473805 Common pgi glucose-6-phosphate isomerase BQ01300 195 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 49474552 Common gcvT Glycine cleavage system protein t BQ10130 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 49474158 Common argC N-acetyl-gamma-glutamyl-phosphate reductase BQ05380 197 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 49474418 Common pcm2 Protein-L-isoaspartate(D-aspartate) O-methyltransferase BQ08380 157 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 49473859 Common pepA Leucyl aminopeptidase BQ01920 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 49474810 Common nspC Carboxynorspermidine decarboxylase BQ13380 75 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 49474176 Pathogen - hypothetical protein BQ05570 1 None None None 49473907 Common - hypothetical protein BQ02450 7 None None None 49473752 Common def Polypeptide deformylase BQ00690 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 49474102 Common - DNA polymerase III subunit chi BQ04640 34 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 49474248 Common vacB Exoribonuclease, VacB and RNase II family BQ06430 192 COG0557 VacB, Exoribonuclease R Transcription 49474491 Common - hypothetical protein BQ09320 14 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 49474376 Common recA recombinase A BQ07950 227 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 49474430 Common - hypothetical protein BQ08560 116 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 49474133 Common cinA Competence /damage-inducible protein cinA BQ04970 192 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 49474509 Common - hypothetical protein BQ09510 181 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 49474424 Common - Potassium-efflux system protein BQ08490 210 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 49474017 Common - hypothetical protein BQ03770 8 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 49473995 Common aroC chorismate synthase BQ03510 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 49474456 Common murG N-acetylglucosaminyl transferase BQ08860 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 49474596 Common - hypothetical protein BQ10720 101 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 49474448 Common comL Competence lipoprotein comL precursor BQ08780 127 COG4105 ComL, DNA uptake lipoprotein General function prediction only 49474229 Common radC DNA repair protein radC BQ06240 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 49474343 Common rnd2 Ribonuclease D BQ07560 123 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 49474700 Common - hypothetical protein BQ12130 35 None None None 49473842 Common ugpA Sn-glycerol-3-phosphate transport system permease protein ugpA BQ01750 157 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 49474531 Common - putative inner membrane protein translocase component YidC BQ09780 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 49474775 Common tyrA chorismate mutase BQ12930 49 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 49473965 Common - hypothetical protein BQ03190 151 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 49473838 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein BQ01710 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 49474016 Common ppdK pyruvate phosphate dikinase BQ03760 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 49474072 Common - hypothetical protein BQ04340 75 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 49473924 Common - ABC transporter ATP-binding protein BQ02700 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 49474189 Common nuoM NADH dehydrogenase subunit M BQ05760 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 49474207 Common - cysteine desulfurase activator complex subunit SufB BQ05950 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 49474313 Common secE preprotein translocase subunit SecE BQ07190 31 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 49474045 Common thiE thiamine-phosphate pyrophosphorylase BQ04070 146 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 49473910 Common - hypothetical protein BQ02480 209 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 49473755 Common - hypothetical protein BQ00720 13 COG5568 COG5568, Uncharacterized small protein Function unknown 49473869 Common rbfA ribosome-binding factor A BQ02020 58 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 49474477 Common dnaG DNA primase BQ09170 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 49474351 Common glmU UDP-N-acetylglucosamine pyrophosphorylase BQ07650 234 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 49473891 Common gshB glutathione synthetase BQ02290 139 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 49473804 Common acrD Acriflavin resistance protein d BQ01290 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 49474146 Common - hypothetical protein BQ05250 162 COG0316 IscA, Uncharacterized conserved protein Function unknown 49474056 Common slt Soluble lytic murein transglycosylase precursor BQ04180 143 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 49473978 Common lgt prolipoprotein diacylglyceryl transferase BQ03340 187 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 49473773 Common mutS DNA mismatch repair protein BQ00930 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 49474198 Common - hypothetical protein BQ05860 14 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 49473767 Common pncB nicotinate phosphoribosyltransferase BQ00840 60 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 49474461 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase BQ08910 213 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 49474786 Common - hypothetical protein BQ13060 46 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 49473981 Common - hypothetical protein BQ03370 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 49473800 Common fur1 Iron response regulator BQ01230 148 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 49474021 Common ptrB Protease II BQ03810 104 COG1770 PtrB, Protease II Amino acid transport and metabolism 49473867 Common - Transport transmembrane protein BQ02000 149 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 49473960 Common atpE F0F1 ATP synthase subunit C BQ03140 41 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 49473763 Common yfeB Iron transport protein yfeB BQ00800 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 49474760 Common rimM 16s rRNA processing protein rimM BQ12750 167 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 49474119 Common ppiD Peptidyl-prolyl cis-trans isomerase protein BQ04830 123 None None None 49473708 Common prfC Peptide chain release factor 3 BQ00230 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 49473938 Common pyrD dihydroorotate dehydrogenase 2 BQ02890 188 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 49474300 Common clpA Endopeptidase clp ATP-binding chain a BQ07050 237 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 49474306 Common rpoC DNA-directed RNA polymerase subunit beta' BQ07120 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 49473918 Common mutL DNA mismatch repair protein BQ02570 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 49473919 Common - 2'-deoxycytidine 5'-triphosphate deaminase BQ02580 35 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 49473839 Common - hypothetical protein BQ01720 153 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 49473959 Common atpB F0F1 ATP synthase subunit A BQ03130 205 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 49474562 Common - Probable surface protein BQ10290 18 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 49474767 Common rpmB 50S ribosomal protein L28 BQ12830 139 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 49473776 Common - hypothetical protein BQ00960 60 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 49474015 Common - hypothetical protein BQ03750 87 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 49474650 Common - phage related protein BQ11500 44 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 49474329 Common dksA DnaK suppressor protein BQ07420 154 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 49474581 Common - 17-kDa antigen precursor BQ10560 6 None None None 49474732 Common trwN trwN protein BQ12470 15 None None None 49474226 Common - RNA methyltransferase BQ06210 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 49473930 Common - hypothetical protein BQ02810 13 None None None 49474758 Common rplS 50S ribosomal protein L19 BQ12730 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 49473853 Common fur2 Iron response regulator BQ01860 194 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 49474602 Common hisS histidyl-tRNA synthetase BQ10830 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49474245 Common - hypothetical protein BQ06400 170 COG0344 COG0344, Predicted membrane protein Function unknown 49473827 Common typA GTP-binding protein typA BQ01590 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 49474765 Common cobS Cobalamin biosynthesis protein cobS BQ12800 60 COG0714 COG0714, MoxR-like ATPases General function prediction only 49474386 Common rpmD 50S ribosomal protein L30 BQ08050 37 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 49474681 Common thiE2 thiamine-phosphate pyrophosphorylase BQ11920 34 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 49474168 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III BQ05480 223 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 49474281 Common - ABC transporter, periplasmic amino acid-binding protein BQ06860 173 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 49473878 Common tlyC Hemolysin BQ02110 215 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 49473719 Common aarF Ubiquinone biosynthesis protein Aarf BQ00350 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 49473693 Common dnaQ DNA polymerase III epsilon chain BQ00050 200 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 49474085 Common rplI 50S ribosomal protein L9 BQ04470 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 49474234 Common livJ Branched chain aa ABC transporter, periplasmic aa-binding protein BQ06290 137 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 49474093 Common fabF1 3-oxoacyl-(acyl carrier protein) synthase II BQ04550 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 49474543 Common vceB Multidrug resistance protein vceB BQ10030 193 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 49474485 Common aatA aspartate aminotransferase BQ09260 236 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 49474271 Common - ATP-dependent RNA helicase BQ06760 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 49474670 Common - hypothetical protein BQ11790 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 49473790 Common recF recombination protein F BQ01130 164 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 49473943 Common folD Methylenetetrahydrofolate dehydrogenase BQ02960 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 49474510 Common - ABC transporter, ATP-binding protein BQ09530 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 49474436 Common thyA thymidylate synthase BQ08630 141 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 49473894 Common pstA Phosphate transport system permease protein BQ02320 226 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 49474655 Pathogen yopP hypothetical intracellular effector BQ11580 7 None None None 49474035 Common htrA1 Serine protease BQ03970 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 49474111 Common tatB hypothetical protein BQ04750 8 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 49474521 Common etfB Electron transfer flavoprotein beta-subunit BQ09670 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 49474321 Common - NADH-ubiquinone oxidoreductase BQ07330 36 None None None 49474086 Common - hypothetical protein BQ04480 7 None None None 49474708 Common - transport protein transmembrane BQ12210 47 None None None 49474636 Pathogen rpmJ 50S ribosomal protein L36 BQ11310 1 None None None 49474471 Common - hypothetical protein BQ09040 4 None None None 49474334 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase BQ07470 166 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 49474288 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase BQ06930 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 49474640 Pathogen - hypothetical protein BQ11380 1 None None None 49474398 Common rpsC 30S ribosomal protein S3 BQ08170 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 49473735 Common - ABC transporter (permease) BQ00510 88 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 49474563 Common fatB Ferric anguibactin-binding protein BQ10300 61 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 49473745 Common argB acetylglutamate kinase BQ00620 221 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 49473880 Common phoH Phosphate starvation-induced protein phoH BQ02130 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 49474445 Common - Aminopeptidase p protein BQ08750 230 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 49474823 Common ispZ intracellular septation protein A BQ13510 91 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 49474391 Common rpsN 30S ribosomal protein S14 BQ08100 203 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 49473885 Common - hypothetical protein BQ02190 166 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 49474069 Common panC Pantoate-beta-alanine ligase BQ04310 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 49474166 Common - hypothetical protein BQ05460 23 None None None 49474742 Common trwM trwM protein BQ12570 22 COG3702 VirB3, Type IV secretory pathway, VirB3 components Intracellular trafficking and secretion 49474427 Common cycA D-serine /D-alanine /glycine transporter BQ08530 152 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 49474621 Common - hypothetical protein BQ11100 2 None None None 49473793 Common cyoB Cytochrome o ubiquinol oxidase subunit I BQ01160 172 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 49474660 Common dut Deoxyuridine 5 27-triphosphate nucleotidohydrolase BQ11670 177 COG0756 Dut, dUTPase Nucleotide transport and metabolism 49474747 Common trwJ2 trwJ2 protein BQ12620 11 None None None 49474457 Common ftsW Cell division protein ftsW BQ08870 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 49474365 Common coaD phosphopantetheine adenylyltransferase BQ07840 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 49474610 Common - Sensory transduction histidine kinase BQ10990 35 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 49474132 Common - hypothetical protein BQ04960 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 49474815 Common sucD succinyl-CoA synthetase subunit alpha BQ13430 212 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 49474029 Common feuP Two-component system regulatory protein BQ03910 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 49474431 Common miaA RNA delta (2)-isopentenylpyrophosphate transferase BQ08580 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 49474530 Common rnpA ribonuclease P BQ09770 49 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 49473976 Common - hypothetical protein BQ03320 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 49474370 Common glnA2 Glutamine synthetase I BQ07890 227 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 49474358 Pathogen - hypothetical protein BQ07720 1 None None None 49474495 Common - Regulatory protein BQ09360 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 49474402 Common rplW 50S ribosomal protein L23 BQ08210 228 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 49473908 Common - Nitrogen fixation protein BQ02460 205 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 49474342 Common aspS aspartyl-tRNA synthetase BQ07550 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49474501 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase BQ09430 219 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 49474776 Common ffh Signal recognition particle protein BQ12940 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 49473935 Pathogen - Sensory box histidine kinase BQ02860 3 None None None 49474508 Common - degT /dnrJ /eryC1 /strS family protein BQ09500 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 49473782 Pathogen - hypothetical protein BQ01050 1 None None None 49474205 Common - hypothetical protein BQ05930 86 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 49474447 Common recN DNA repair protein recN BQ08770 213 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 49474018 Pathogen - hypothetical protein BQ03780 1 None None None 49474450 Common ftsZ cell division protein FtsZ BQ08800 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 49474553 Common lon2 ATP-dependent protease lon BQ10140 72 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 49474555 Common asd aspartate-semialdehyde dehydrogenase BQ10170 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 49474126 Common - hypothetical protein BQ04900 21 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 49474805 Common phaE putative monovalent cation/H+ antiporter subunit E BQ13330 41 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 49474538 Pathogen - hypothetical protein BQ09910 1 None None None 49474667 Common - hypothetical protein BQ11760 152 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 49474545 Common odc Ornithine decarboxylase BQ10050 215 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 49474690 Common tktA transketolase BQ12020 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 49474181 Common nuoE NADH dehydrogenase subunit E BQ05680 154 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 49474721 Common - hypothetical protein BQ12350 36 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 49473830 Common - Peptidoglycan-binding protein BQ01630 101 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 49473840 Common ugpC Sugar ABC transporter, ATP-binding protein BQ01730 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 49473954 Common - hypothetical protein BQ03080 5 None None None 49474377 Common - recombination factor protein RarA BQ07960 232 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 49474100 Common - hypothetical protein BQ04620 70 COG0795 COG0795, Predicted permeases General function prediction only 49474157 Common - Cytochrome c oxidase assembly protein BQ05370 65 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 49474101 Common - hypothetical protein BQ04630 54 COG0795 COG0795, Predicted permeases General function prediction only 49474350 Common glmS D-fructose-6-phosphate amidotransferase BQ07640 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 49473728 Common - hypothetical protein BQ00440 40 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 49473746 Common - hypothetical protein BQ00630 84 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 49474221 Common dacA1 Penicillin-binding protein BQ06120 150 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 49474237 Common livG High-affinity branched-chain amino acid transport, ATP-binding protein BQ06320 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 49473828 Common mgtE Mg2+ transport protein BQ01600 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 49473868 Common truB tRNA pseudouridine synthase B BQ02010 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 49474243 Common pyrB aspartate carbamoyltransferase catalytic subunit BQ06380 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 49474210 Common nifS2 Nitrogenase cofactor synthesis protein nifS BQ05980 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 49473803 Common - hypothetical protein BQ01280 161 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 49474145 Common ibpA2 Small heat shock protein BQ05230 73 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 49474597 Common groEL chaperonin GroEL BQ10750 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 49474301 Common - hypothetical protein BQ07060 115 COG2127 COG2127, Uncharacterized conserved protein Function unknown 49473747 Common lepA GTP-binding protein LepA BQ00640 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 49474679 Common - hypothetical protein BQ11900 15 COG5317 COG5317, Uncharacterized protein conserved in bacteria Function unknown 49474472 Pathogen - hypothetical protein BQ09050 3 COG3422 COG3422, Uncharacterized conserved protein Function unknown 49473762 Common yfeA Iron transport protein yfeA BQ00790 165 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 49473861 Common ansA L-asparaginase BQ01940 114 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 49474768 Common surF1 SurF1 family protein (Surfeit 1) BQ12840 47 COG3346 COG3346, Uncharacterized conserved protein Function unknown 49474307 Common rpoB DNA-directed RNA polymerase subunit beta BQ07130 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 49473766 Common - hypothetical protein BQ00830 71 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 49473812 Common badA3 Surface protein/Bartonella adhesin BQ01410 21 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 49474003 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase BQ03600 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 49474526 Common - hypothetical protein BQ09720 57 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 49474190 Common nuoN NADH dehydrogenase subunit N BQ05770 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 49473975 Common prsA ribose-phosphate pyrophosphokinase BQ03310 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 49474167 Common plsX fatty acid/phospholipid synthesis protein BQ05470 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 49473829 Common - hypothetical protein BQ01620 27 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 49474057 Common dapA dihydrodipicolinate synthase BQ04190 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 49473987 Common - hypothetical protein BQ03430 229 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 49474476 Common rpoD RNA polymerase sigma factor RpoD BQ09160 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 49474204 Common tyrS tyrosyl-tRNA synthetase BQ05920 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49474312 Common nusG transcription antitermination protein NusG BQ07180 215 COG0250 NusG, Transcription antiterminator Transcription 49473968 Common sohB Protease sohB BQ03220 187 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 49474785 Common - hypothetical protein BQ13050 38 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 49474657 Common - hypothetical protein BQ11640 52 COG1238 COG1238, Predicted membrane protein Function unknown 49473879 Common - hypothetical protein BQ02120 209 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 49473998 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase BQ03540 227 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 49474341 Common parC DNA topoisomerase IV subunit A BQ07540 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 49474647 Common - hypothetical protein BQ11460 2 None None None 49474044 Common thiD1 Phosphomethylpyrimidine kinase BQ04060 222 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 49474084 Common dnaB replicative DNA helicase BQ04460 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 49473877 Common lnt apolipoprotein N-acyltransferase BQ02100 163 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 49474294 Common pyrH uridylate kinase BQ06990 241 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 49473720 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase BQ00360 216 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 49474112 Common tatC Sec-independent protein translocase component BQ04760 204 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 49474682 Common - hypothetical protein BQ11930 78 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 49473700 Common ihfB integration host factor subunit beta BQ00130 207 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 49473951 Common ubiG 3-demethylubiquinone-9 3-methyltransferase BQ03050 113 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 49474299 Common - Hit-like protein involved in cell-cycle regulation BQ07040 237 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 49474766 Common cobT Cobalamin biosynthesis protein cobT BQ12810 47 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 49473843 Common ugpB Glycerol-3-phosphate-binding periplasmic protein precursor ugpB BQ01760 99 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 49474542 Common vceA Multidrug resistance protein vceA BQ10020 143 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 49474484 Common - Cold shock protein BQ09250 177 COG1278 CspC, Cold shock proteins Transcription 49474794 Common plsC 1-acyl-sn-glycerol-3-phosphate acyltransferase BQ13210 157 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 49474731 Pathogen - hypothetical protein BQ12460 1 None None None 49474073 Common pyrC1 dihydroorotase BQ04350 209 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 49474244 Common pyrC2 dihydroorotase BQ06390 208 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 49474800 Common aroB 3-dehydroquinate synthase BQ13280 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 49474437 Common kgtP Alpha-ketoglutarate permease BQ08640 156 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 49474308 Common rplL 50S ribosomal protein L7/L12 BQ07140 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 49474258 Common - hypothetical protein BQ06590 87 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 49473709 Common trxA Thioredoxin BQ00240 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 49474270 Common ppnK inorganic polyphosphate/ATP-NAD kinase BQ06750 236 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 49474580 Common virB4 virB4 protein homolog BQ10550 56 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 49474755 Common sdhA succinate dehydrogenase flavoprotein subunit BQ12700 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 49473785 Common ccmA Heme exporter protein A BQ01080 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 49473831 Common galU UTP-glucose-1-phosphate uridylyltransferase BQ01640 229 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 49474589 Common - Putative cell filamentation protein BQ10650 29 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 49474380 Common rpoA DNA-directed RNA polymerase subunit alpha BQ07990 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 49473854 Common secA preprotein translocase subunit SecA BQ01870 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 49474298 Common - hypothetical protein BQ07030 102 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 49474612 Pathogen - hypothetical protein BQ11010 1 None None None 49474008 Pathogen - hypothetical protein BQ03680 1 None None None 49474535 Common gpmA phosphoglyceromutase BQ09820 179 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 49474224 Common rpsD 30S ribosomal protein S4 BQ06190 217 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 49473860 Common coaA pantothenate kinase BQ01930 76 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 49474583 Common - 15-kDa antigen protein BQ10580 3 None None None 49474000 Common tldD tldD protein BQ03570 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 49474678 Common ruvC Holliday junction resolvase BQ11890 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 49473750 Common truA tRNA pseudouridine synthase A BQ00670 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 49474689 Common gap glyceraldehyde-3-phosphate dehydrogenase BQ12000 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 49474722 Common - hypothetical protein BQ12360 31 COG1434 COG1434, Uncharacterized conserved protein Function unknown 49474087 Common rpsR 30S ribosomal protein S18 BQ04490 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 49474734 Pathogen trwL1 trwL1 protein BQ12490 1 None None None 49474276 Common - hypothetical protein BQ06810 13 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 49473953 Common nhaA Na+/H antiporter BQ03070 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 49474763 Common bolA Transcriptional regulator bolA BQ12780 89 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 49474719 Common acs acetyl-CoA synthetase BQ12330 217 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 49474464 Common mraW S-adenosyl-methyltransferase MraW BQ08940 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 49473770 Common cmk cytidylate kinase BQ00870 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 49474579 Common virB3 virB3 protein homolog BQ10540 12 COG3702 VirB3, Type IV secretory pathway, VirB3 components Intracellular trafficking and secretion 49474648 Common - hypothetical protein BQ11480 12 COG3756 COG3756, Uncharacterized protein conserved in bacteria Function unknown 49474680 Common opgC opgC protein BQ11910 30 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 49474816 Common sucC succinyl-CoA synthetase subunit beta BQ13440 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 49474246 Common dprA DNA processing chain A BQ06410 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 49473704 Common ptsN Nitrogen regulatory IIA BQ00170 138 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 49474383 Common adk adenylate kinase BQ08020 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 49473963 Common glyS glycyl-tRNA synthetase subunit beta BQ03170 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 49473779 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein BQ01010 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 49474182 Common nuoF NADH dehydrogenase I, F subunit BQ05690 166 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 49473807 Common rpmA 50S ribosomal protein L27 BQ01330 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 49473949 Common comF Competence protein comF BQ03030 136 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 49473997 Common xseB exodeoxyribonuclease VII small subunit BQ03530 121 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 49474159 Common glyA serine hydroxymethyltransferase BQ05390 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 49473706 Common - hypothetical protein BQ00190 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 49474019 Common - hypothetical protein BQ03790 96 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 49473866 Common rpsO 30S ribosomal protein S15 BQ01990 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 49474178 Common nuoB NADH dehydrogenase subunit B BQ05650 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 49474305 Common pnbA Nitroreductase BQ07100 90 COG0778 NfnB, Nitroreductase Energy production and conversion 49474097 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase BQ04590 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 49474547 Common - hypothetical protein BQ10070 108 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 49473986 Common rnhB ribonuclease HII BQ03420 228 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 49474714 Common priA primosome assembly protein PriA BQ12280 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 49474148 Common adh Alcohol dehydrogenase (quinone oxidoreductase) BQ05280 195 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 49474199 Common rne Ribonuclease E BQ05870 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 49473761 Common pheT phenylalanyl-tRNA synthetase subunit beta BQ00780 243 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 49474216 Common - hypothetical protein BQ06070 74 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 49474043 Common - DNA polymerase, bacteriophage type BQ04050 153 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 49474256 Pathogen - hypothetical protein BQ06550 1 None None None 49474319 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B BQ07280 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 49474710 Common atpD F0F1 ATP synthase subunit beta BQ12230 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 49473724 Common - hypothetical protein BQ00400 141 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 49474231 Common - Hydrolase BQ06260 149 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 49474252 Common - Transcriptional regulator BQ06470 97 COG1522 Lrp, Transcriptional regulators Transcription 49474364 Common ppiB2 Peptidyl-prolyl cis-trans isomerase b BQ07830 198 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 49474219 Common dnaC DNA polymerase III subunit delta' BQ06100 236 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 49474455 Common murC UDP-N-acetylmuramate--L-alanine ligase BQ08850 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 49474433 Common hflC ftsH protease activity modulator hflC BQ08600 187 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 49474496 Common - hypothetical protein BQ09370 60 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 49473849 Common nrdE ribonucleotide-diphosphate reductase subunit alpha BQ01820 215 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 49474034 Common cycL Cytochrome c-type biogenesis protein cycL BQ03960 91 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 49474041 Common - Two-component sensor histidine kinase BQ04030 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 49473847 Common nrdH Glutaredoxin-like protein nrdH BQ01800 35 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 49474349 Common recG ATP-dependent DNA helicase recG BQ07630 221 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 49474117 Common - Outer membrane protein BQ04810 16 COG3737 COG3737, Uncharacterized conserved protein Function unknown 49474572 Common - hypothetical protein BQ10460 40 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 49474635 Pathogen - hypothetical protein BQ11300 1 None None None 49474269 Common hutH histidine ammonia-lyase BQ06730 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 49474697 Common - hypothetical protein BQ12100 38 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 49473923 Common pheP Phenylalanine-specific permease BQ02690 163 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 49473922 Pathogen - hypothetical protein BQ02680 1 None None None 49474076 Common - hypothetical protein BQ04380 25 COG2323 COG2323, Predicted membrane protein Function unknown 49474074 Common - hypothetical protein BQ04360 16 COG5451 COG5451, Predicted secreted protein Function unknown 49474292 Common cdsA2 Phosphatidate cytidylyltransferase BQ06970 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 49473982 Common envZ Sensor histidine kinase BQ03380 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 49474408 Common rpsG 30S ribosomal protein S7 BQ08270 231 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 49474318 Common - NADH dehydrogenase BQ07270 38 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 49474136 Common ntrY Nitrogen regulation protein BQ05000 219 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 49473784 Common ccmB Heme exporter protein B BQ01070 79 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 49474378 Common htrA2 Heat shock protein BQ07970 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 49474746 Pathogen trwH1 hypothetical protein BQ12610 1 None None None 49473738 Pathogen - hypothetical protein BQ00540 3 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 49474412 Common gltJ Amino acid permease BQ08310 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 49473821 Common ctpA Carboxy-terminal processing protease ctpA BQ01530 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 49473717 Common accD acetyl-CoA carboxylase subunit beta BQ00320 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 49474353 Common - hypothetical protein BQ07670 13 None None None 49474454 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase BQ08840 138 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 49474528 Common mrp mrp protein BQ09750 228 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 49473835 Common - Phopholipase D-family protein BQ01680 148 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 49474371 Pathogen - hypothetical protein BQ07900 2 None None None 49474600 Common pgm phosphoglucomutase BQ10790 208 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 49474372 Common - hypothetical protein BQ07910 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 49474533 Common - Glutathione S-transferase BQ09800 48 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 49474808 Common phaA putative monovalent cation/H+ antiporter subunit A BQ13360 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 49474551 Common gcvH glycine cleavage system protein H BQ10120 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 49473760 Common pheS Phenylalanyl-tRNA synthetase alpha chain BQ00770 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 49473814 Common - hypothetical protein BQ01430 4 None None None 49474340 Common - Bicyclomycin resistance protein BQ07530 229 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 49474446 Common ligA NAD-dependent DNA ligase LigA BQ08760 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 49474330 Common nmoB 4-hydroxyphenylacetate 3-monooxygenase BQ07430 104 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 49474384 Common secY preprotein translocase subunit SecY BQ08030 230 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 49474598 Common groES co-chaperonin GroES BQ10760 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 49474177 Common nuoA NADH dehydrogenase subunit A BQ05640 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 49474118 Common - hypothetical protein BQ04820 47 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 49474773 Common - hypothetical protein BQ12910 21 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 49474236 Common livM High-affinity branched-chain amino acid transporter, permease protein BQ06310 143 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 49474507 Common - hypothetical protein BQ09490 7 None None None 49474544 Common - Acetyltransferase BQ10040 72 COG3153 COG3153, Predicted acetyltransferase General function prediction only 49474209 Common - hypothetical protein BQ05970 181 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 49473699 Common - hypothetical protein BQ00120 14 None None None 49474054 Common hutA Heme receptor precursor BQ04160 106 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 49474566 Common ceuD Iron compound ABC transporter BQ10330 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 49474103 Pathogen - hypothetical protein BQ04650 1 None None None 49474419 Common hbpE Hemin binding protein E BQ08430 16 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 49474259 Common lipB lipoyltransferase BQ06600 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 49474793 Common thiD2 Phosphomethylpyrimidine kinase BQ13200 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 49474738 Pathogen trwL5 trwL5 protein BQ12530 1 None None None 49473742 Common - hypothetical protein BQ00580 75 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 49474504 Common ctrA Cell cycle transcriptional regulator ctra BQ09460 211 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 49474444 Common prmA ribosomal protein L11 methyltransferase BQ08740 177 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 49474824 Common gloB Hydroxyacylglutathione hydrolase BQ13520 198 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 49473710 Common addA ATP-dependent nuclease subunit A BQ00250 226 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 49474470 Common - hypothetical protein BQ09030 40 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 49473795 Common cyoD Cytochrome o ubiquinol oxidase subunit IV BQ01180 47 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 49474534 Common - dihydrodipicolinate reductase BQ09810 214 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 49474511 Common oppD Oligopeptide transport ATP-binding protein BQ09540 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 49474161 Common ribD Riboflavin biosynthesis protein ribD BQ05410 226 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 49474626 Common - hypothetical protein BQ11160 2 None None None 49473815 Common ftsJ Cell division protein ftsJ BQ01450 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 49474426 Common - hypothetical protein BQ08510 216 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 49474284 Common - Amino-acid ABC transporter BQ06890 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 49474518 Common - hypothetical protein BQ09640 28 None None None 49474322 Pathogen - hypothetical protein BQ07350 1 None None None 49474498 Common - hypothetical protein BQ09390 33 COG5426 COG5426, Uncharacterized membrane protein Function unknown 49473939 Common glnA1 Glutamine synthetase BQ02910 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 49474788 Common - Thiol 3adisulfide interchange protein BQ13100 120 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 49473690 Common maf-1 Septum formation maf protein BQ00020 178 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 49474707 Common - transport protein transmembrane BQ12200 118 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 49474607 Common sigH RNA polymerase sigma factor BQ10960 140 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 49473751 Common fmt Methionyl-tRNA formyltransferase BQ00680 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 49473932 Common rluD Ribosomal large subunit pseudouridine synthase D BQ02830 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 49474658 Common - hypothetical protein BQ11650 29 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 49474179 Common nuoC NADH dehydrogenase subunit C BQ05660 176 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 49473723 Common comM Competence protein comM BQ00390 196 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 49474829 Common trmE tRNA modification GTPase TrmE BQ13570 217 COG0486 ThdF, Predicted GTPase General function prediction only 49474733 Pathogen korA korA protein BQ12480 1 None None None 49473888 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase BQ02230 138 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 49473990 Common purD phosphoribosylamine--glycine ligase BQ03460 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 49473771 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase BQ00880 230 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 161761284 Common rncS ribonuclease III BQ04280 216 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 49474523 Common - Electron transfer flavoprotein-ubiquinone oxidoreductase BQ09690 110 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 49474740 Pathogen trwL7 trwL7 protein BQ12550 1 None None None 49474578 Common virB2 virB2 protein homolog BQ10530 8 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 49474110 Common tatA hypothetical protein BQ04740 2 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 49474787 Common lysA Diaminopimelate decarboxylase BQ13070 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 49474802 Common - hypothetical protein BQ13300 9 COG3895 COG3895, Predicted periplasmic protein General function prediction only 49474764 Common - DnaJ related protein BQ12790 154 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 49474185 Common nuoI NADH dehydrogenase subunit I BQ05720 191 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 49474337 Common purL phosphoribosylformylglycinamidine synthase II BQ07500 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 49473778 Common hslO Hsp33-like chaperonin BQ00990 131 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 49474239 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A BQ06340 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 49474813 Common sucB dihydrolipoamide acetyltransferase BQ13410 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 49474277 Common rpiA ribose-5-phosphate isomerase A BQ06820 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 49474780 Common - hypothetical protein BQ12990 27 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 49473705 Common - hypothetical protein BQ00180 28 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 49474001 Common - hypothetical protein BQ03580 15 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 49474049 Common thiC thiamine biosynthesis protein ThiC BQ04110 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 49473707 Common lysK lysyl-tRNA synthetase BQ00220 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 49474291 Common - Membrane-associated zinc metalloprotease BQ06960 208 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 49474009 Pathogen - hypothetical protein BQ03690 1 None None None 49474297 Common - hypothetical protein BQ07020 18 None None None 49474677 Common ruvA Holliday junction DNA helicase motor protein BQ11880 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 49473787 Common rpsT 30S ribosomal protein S20 BQ01100 104 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 49474757 Common sdhC Succinate dehydrogenase cytochrome b560 subunit BQ12720 47 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 49474191 Common birA Biotin-protein ligase birA BQ05780 222 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 49474582 Common virB6 virB6 protein homolog BQ10570 39 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 49474022 Common sodB Superoxide dismutase BQ03820 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 49473871 Common - hypothetical protein BQ02040 40 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 49474400 Common rpsS 30S ribosomal protein S19 BQ08190 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 49473753 Common - hypothetical protein BQ00700 140 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 49474095 Common gmk Guanylate kinase BQ04570 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 49474010 Pathogen - hypothetical protein BQ03700 1 None None None 49474698 Common - hypothetical protein BQ12110 127 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 49474611 Common - hypothetical protein BQ11000 31 None None None 49473737 Common - Fructose-specific IIa component BQ00530 95 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 49474042 Common pepN Aminopeptidase N BQ04040 159 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 49474490 Common greA transcription elongation factor GreA BQ09310 204 COG0782 GreA, Transcription elongation factor Transcription 49473921 Common - Phage related lysozyme BQ02630 50 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 49474040 Common - Methyltransferase (fragment) BQ04020 202 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 49474211 Common - hypothetical protein BQ05990 146 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 49474075 Common cysS cysteinyl-tRNA synthetase BQ04370 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49474268 Pathogen - hypothetical protein BQ06720 1 None None None 49474573 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase BQ10470 211 COG0196 RibF, FAD synthase Coenzyme metabolism 49473837 Common sun1 SUN protein (FMU protein) BQ01700 205 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 49474409 Common rpsL 30S ribosomal protein S12 BQ08280 236 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 49474438 Common - hypothetical protein BQ08670 9 None None None 49474077 Common - ABC transporter, ATP-binding protein BQ04390 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 49473848 Common nrdI ribonucleotide reductase stimulatory protein BQ01810 39 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 49474253 Common - tRNA-dihydrouridine synthase A BQ06500 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 49473985 Common - hypothetical protein BQ03410 8 None None None 49474150 Common fabF3 3-oxoacyl-(acyl carrier protein) synthase II BQ05300 29 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 49473897 Common - hypothetical protein BQ02350 29 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 49473851 Common hemK Protoporphyrinogen oxidase protein BQ01840 228 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 49473917 Common - hypothetical protein BQ02560 22 COG3908 COG3908, Uncharacterized protein conserved in bacteria Function unknown 49474230 Common - hypothetical protein BQ06250 18 None None None 49474546 Pathogen - hypothetical protein BQ10060 1 None None None 49474147 Common - lipid A biosynthesis lauroyl acyltransferase BQ05270 95 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 49474463 Common - hypothetical protein BQ08930 16 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 49474134 Common ispDF IspD/ispF bifunctional enzyme BQ04980 196 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 49474039 Common hbpD Hemin binding protein d BQ04010 15 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 49474638 Common - hypothetical protein BQ11340 152 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 49474564 Common fatD Ferric anguibactin transport system permease protein BQ10310 189 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 49474218 Common metG methionyl-tRNA synthetase BQ06090 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49474713 Common atpH ATP synthase delta chain BQ12260 135 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 49474257 Common lemA Cytoplasmic membrane protein BQ06580 130 COG1704 LemA, Uncharacterized conserved protein Function unknown 49473889 Common - hypothetical protein BQ02240 56 COG3474 COG3474, Cytochrome c2 Energy production and conversion 49474033 Common cycK Cytochrome c-type biogenesis protein cycK BQ03950 144 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 49474623 Common - hypothetical protein BQ11120 2 None None None 49474662 Common exbB Biopolymer transport exbB protein BQ11710 139 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 49473813 Common - hypothetical protein BQ01420 4 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 49473988 Common - Oxidoreductase BQ03440 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 49474127 Common pdhA Pyruvate dehydrogenase E1 component, alpha subunit BQ04910 159 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 49474171 Common thrS threonyl-tRNA synthetase BQ05510 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49473718 Common dfp bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase BQ00340 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 49474413 Common gltK Amino acid permease BQ08320 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 49473722 Common - ABC transporter, periplasmic amino acid-binding protein BQ00380 64 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 49474055 Common tonB tonB protein BQ04170 12 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 49473711 Common - hypothetical protein BQ00260 48 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 49473906 Common ileS isoleucyl-tRNA synthetase BQ02440 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49474385 Common rplO 50S ribosomal protein L15 BQ08040 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 49474516 Common tag DNA-3-methyladenine glycosylase I BQ09600 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 49474092 Common acpP acyl carrier protein BQ04540 208 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 49474532 Common cgpA GTPase EngB BQ09790 174 COG0218 COG0218, Predicted GTPase General function prediction only 49474774 Common rpsP 30S ribosomal protein S16 BQ12920 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 49474624 Common - hypothetical protein BQ11130 11 None None None 49473841 Common ugpE Sn-glycerol-3-phosphate transport system permease protein ugpE BQ01740 145 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 49474567 Common - hypothetical protein BQ10350 4 COG1409 Icc, Predicted phosphohydrolases General function prediction only 49474584 Common virB8 virB8 protein homolog BQ10590 33 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 49473937 Common mscL Large-conductance mechanosensitive channel BQ02880 104 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 49474183 Common nuoG NADH dehydrogenase subunit G BQ05700 192 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 49474637 Common - hypothetical signal peptide protein BQ11320 27 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 49474373 Common rluC Ribosomal large subunit pseudouridine synthase c BQ07920 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 49474379 Common rplQ 50S ribosomal protein L17 BQ07980 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 49474781 Common - hypothetical protein BQ13000 15 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 49473992 Common pdxH pyridoxamine 5'-phosphate oxidase BQ03480 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 49473956 Common - hypothetical protein BQ03100 23 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 49474328 Common - hypothetical protein BQ07410 11 None None None 49474669 Common - hypothetical protein BQ11780 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 49474283 Common - ABC transporter, permease protein BQ06880 173 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 49473806 Common rplU 50S ribosomal protein L21 BQ01320 195 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 49474227 Common sfsA sugar fermentation stimulation protein A BQ06220 107 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 49473836 Common guaB inositol-5-monophosphate dehydrogenase BQ01690 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 49473966 Common ispB Octaprenyl-diphosphate synthase BQ03200 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 49474608 Pathogen - hypothetical protein BQ10970 1 None None None 49474529 Common rpmH 50S ribosomal protein L34 BQ09760 194 None None None 49474750 Common trwG trwG protein BQ12650 37 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 49474135 Common rirA iron-responsive transcriptional regulator BQ04990 160 COG1959 COG1959, Predicted transcriptional regulator Transcription 49474807 Common phaC putative monovalent cation/H+ antiporter subunit C BQ13350 81 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 49473892 Common - Periplasmic phosphate binding protein BQ02300 123 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 49474352 Common - Cytochrome c-type biogenesis protein BQ07660 98 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 49474519 Common - hypothetical protein BQ09650 34 COG0730 COG0730, Predicted permeases General function prediction only 49474499 Common - hypothetical protein BQ09400 44 COG1409 Icc, Predicted phosphohydrolases General function prediction only 49474599 Common fumC fumarate hydratase BQ10770 217 COG0114 FumC, Fumarase Energy production and conversion 49474748 Common trwI2 trwI2 protein BQ12630 15 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 49474396 Common rpmC 50S ribosomal protein L29 BQ08150 166 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 49474323 Common - hypothetical protein BQ07360 64 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 49474023 Common - hypothetical toxin secretion protein BQ03850 242 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 49473691 Common aroE Shikimate 5-dehydrogenase BQ00030 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 49474779 Common - glutamine amidotransferase BQ12980 150 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 49474653 Pathogen - hypothetical protein BQ11530 1 None None None 49474821 Common - hypothetical protein BQ13490 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 49474706 Pathogen - hypothetical protein BQ12190 1 None None None 49473899 Common mutM Formamidopyrimidine-DNA glycosylase BQ02370 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 49474745 Common trwI1 trwI1 protein BQ12600 15 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 49473872 Common nusA transcription elongation factor NusA BQ02050 220 COG0195 NusA, Transcription elongation factor Transcription 49473999 Common tlyA Hemolysin-like protein BQ03550 130 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 49473887 Pathogen - hypothetical protein BQ02210 1 None None None 49473792 Common cyoA Cytochrome o ubiquinol oxidase subunit II BQ01150 114 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 49474206 Common nifS1 Nitrogenase cofactor synthesis protein nifS BQ05940 234 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 49474814 Common kgd alpha-ketoglutarate decarboxylase BQ13420 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 49474506 Common - hypothetical protein BQ09480 22 COG5400 COG5400, Uncharacterized protein conserved in bacteria Function unknown 49473822 Common invA dinucleoside polyphosphate hydrolase BQ01540 117 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 49474067 Common era GTP-binding protein Era BQ04290 239 COG1159 Era, GTPase General function prediction only 49474331 Common rpe Pentose (ribulose)-5-phosphate-3-epimerase BQ07440 215 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 49474429 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ BQ08550 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 49473977 Common - hypothetical protein BQ03330 93 COG1565 COG1565, Uncharacterized conserved protein Function unknown 49473743 Common dnaK molecular chaperone DnaK BQ00590 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 49474443 Common - sco1/2 family protein BQ08730 104 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 49474645 Pathogen - hypothetical protein BQ11430 1 None None None 49474289 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase BQ06940 171 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 49474452 Common ftsQ Cell division protein ftsQ BQ08820 57 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 49473759 Common rplT 50S ribosomal protein L20 BQ00760 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 49474233 Common - Cold shock protein BQ06280 149 COG1278 CspC, Cold shock proteins Transcription 49473980 Pathogen - hypothetical protein BQ03360 1 None None None 49473883 Common - hypothetical protein BQ02160 197 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 49474250 Common - hypothetical protein BQ06450 41 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 49474115 Common - Antigen (virulence determinant) (lipoptrotein) BQ04790 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 49473984 Common - hypothetical protein BQ03400 200 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 49474032 Common cycJ cytochrome c-type biogenesis protein CcmE BQ03940 94 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 49473920 Common lldD L-lactate dehydrogenase BQ02590 117 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 49474347 Common - salicylate hydroxylase BQ07610 54 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 49474317 Common - hypothetical protein BQ07260 28 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 49474628 Common - zinc-binding protein BQ11180 24 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 49474254 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BQ06520 197 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 49474656 Common - phage related lysozyme BQ11590 57 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 49474071 Common - hypothetical protein BQ04330 32 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 49474481 Common carA carbamoyl phosphate synthase small subunit BQ09220 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 49474751 Common trwF trwF protein BQ12660 55 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 49473817 Common proB gamma-glutamyl kinase BQ01470 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 49473929 Common purA adenylosuccinate synthetase BQ02800 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 49474389 Common rplF 50S ribosomal protein L6 BQ08080 241 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 49474712 Common atpA F0F1 ATP synthase subunit alpha BQ12250 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 49474716 Common - hypothetical protein BQ12300 10 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 49473864 Common rsmC Ribosomal RNA small subunit methyltransferase c BQ01970 69 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 49474801 Common - hypothetical protein BQ13290 8 COG3895 COG3895, Predicted periplasmic protein General function prediction only 49474570 Pathogen - hypothetical protein BQ10440 3 None None None 49474587 Common virB11 virB11 protein homolog BQ10620 197 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 49474186 Common nuoJ NADH dehydrogenase subunit J BQ05730 86 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 49474327 Common - Sensor histidine kinase BQ07400 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 49473896 Common phoU Phosphate transport system protein phoU BQ02340 195 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 49474336 Common purQ phosphoribosylformylglycinamidine synthase subunit I BQ07490 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 49474525 Common - hypothetical protein BQ09710 4 None None None 49474089 Common - hypothetical protein BQ04510 60 None None None 49474382 Common rpsM 30S ribosomal protein S13 BQ08010 236 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 49473824 Common - hypothetical protein BQ01560 78 COG0762 COG0762, Predicted integral membrane protein Function unknown 49474149 Common fabF2 3-oxoacyl-(acyl carrier protein) synthase II BQ05290 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 49474505 Common - hypothetical protein BQ09470 29 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 49474695 Common - ABC transporter, ATP-binding protein BQ12080 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 49473845 Common - ABC transporter, permease protein BQ01780 185 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 49474333 Common - hypothetical protein BQ07460 53 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 49474737 Pathogen trwL4 trwL4 protein BQ12520 1 None None None 49474062 Common pyrE orotate phosphoribosyltransferase BQ04240 98 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 49474011 Common - Phosphatase BQ03710 160 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 49473913 Common - myo-inositol monophosphatase BQ02520 192 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 49473970 Common - hypothetical protein BQ03250 23 None None None 49474238 Common livF High-affinity branched-chain amino acid transport, ATP-binding protein BQ06330 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 49474736 Pathogen trwL3 trwL3 protein BQ12510 1 None None None 49474753 Common trwD trwD protein BQ12680 200 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 49474048 Common thiO Thiamine biosynthesis oxidoreductase BQ04100 91 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 49474744 Common trwJ1 trwJ1 protein BQ12590 10 None None None 49474687 Common fbaB Fructose-bisphosphate aldolase BQ11980 38 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 49474078 Common psdA phosphatidylserine decarboxylase BQ04400 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 49474222 Common rlpA Rare lipoprotein A BQ06130 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 49474654 Pathogen - hypothetical protein BQ11560 2 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49473857 Common mutT Mutator mutT protein BQ01900 161 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 49474031 Common cycH Cytochrome c-type biogenesis protein cycH BQ03930 18 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 49473955 Common - hypothetical protein BQ03090 117 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 49474274 Common - 2-dehydro-3-deoxyphosphoheptonatealdolase BQ06790 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 49474363 Common ppiB1 Peptidyl prolyl cis-trans isomerase b BQ07820 199 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 49473796 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase BQ01190 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 49474819 Common - Outer membrane lipoprotein BQ13470 7 None None None 49474661 Common exbD Biopolymer transport exbD protein BQ11700 127 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 49474676 Common ruvB Holliday junction DNA helicase B BQ11870 223 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 49474240 Common gatC Glutamyl-tRNA (gln) amidotransferase subunit C BQ06350 154 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 49474273 Common nadE NAD synthetase BQ06780 232 COG0171 NadE, NAD synthase Coenzyme metabolism 49474720 Common ftsE Cell division protein ftsE BQ12340 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 49473850 Common nrdF ribonucleotide-diphosphate reductase subunit beta BQ01830 148 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 49474577 Common - hypothetical protein BQ10520 6 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 49473697 Common lspA Lipoprotein signal peptidase BQ00090 53 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 49474630 Common infA translation initiation factor IF-1 BQ11200 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 49474192 Common - hypothetical protein BQ05790 152 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 49473874 Common trmB tRNA (guanine-N(7))-methyltransferase BQ02070 162 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 49474311 Common rplK 50S ribosomal protein L11 BQ07170 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 49474643 Pathogen - hypothetical protein BQ11410 1 None None None 49474799 Common aroK Shikimate kinase BQ13270 198 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 49474502 Common - hypothetical protein BQ09440 27 None None None 49474348 Common dnaE DNA polymerase III subunit alpha BQ07620 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 49474184 Common nuoH NADH dehydrogenase subunit H BQ05710 190 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 49474646 Pathogen - hypothetical protein BQ11450 1 None None None 49474038 Common glnE Glutamate-ammonia-ligase adenylyltransferase BQ04000 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 49474286 Common cdsA1 Phosphatidate cytidyltransferase BQ06910 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 49474487 Common trxB Thioredoxin reductase BQ09280 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 49474693 Common - hypothetical protein BQ12060 18 COG5480 COG5480, Predicted integral membrane protein Function unknown 49474065 Common lebB Signal peptidase I BQ04270 202 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 49473731 Common hemN coproporphyrinogen III oxidase BQ00470 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 49473882 Common - Peptide N-acetyltransferase BQ02150 174 COG0456 RimI, Acetyltransferases General function prediction only 49474536 Common - omp43 precursor BQ09890 13 None None None 49474129 Common pdhC branched-chain alpha-keto acid dehydrogenase subunit E2 BQ04930 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 49474428 Common ilvC ketol-acid reductoisomerase BQ08540 212 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 49474278 Common - DNA uptake protein BQ06830 164 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 49473732 Common - putative deoxyribonucleotide triphosphate pyrophosphatase BQ00480 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 49473714 Common ahcY S-adenosyl-L-homocysteine hydrolase BQ00290 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 49474163 Common ribH riboflavin synthase subunit beta BQ05430 208 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 49474442 Common uvrD DNA helicase II BQ08710 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 49474128 Common pdhB pyruvate dehydrogenase subunit beta BQ04920 206 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 49474778 Common - hypothetical protein BQ12970 6 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 49474701 Common fdxA Ferredoxin II BQ12140 168 COG1146 COG1146, Ferredoxin Energy production and conversion 49474827 Common gidB glucose-inhibited division protein B BQ13550 189 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 49474605 Common - hypothetical protein BQ10930 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 49474729 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase BQ12440 121 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 49474393 Common rplX 50S ribosomal protein L24 BQ08120 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 49474822 Common ftsY Cell division protein ftsY BQ13500 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 49474324 Common perM Permease protein BQ07370 151 COG0628 PerM, Predicted permease General function prediction only 49474705 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase BQ12180 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 49474423 Common secD bifunctional preprotein translocase subunit SecD/SecF BQ08480 207 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 49474106 Common ndk nucleoside diphosphate kinase BQ04690 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 49474296 Common rpsB 30S ribosomal protein S2 BQ07010 228 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 49474374 Common txpA ABC transporter, ATP-binding protein BQ07930 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 49474410 Common xthA1 Exodeoxyribonuclease III BQ08290 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 49473971 Common - translation-associated GTPase BQ03260 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 49474435 Common folA Dihydrofolate reductase BQ08620 143 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 49474725 Common - hypothetical protein BQ12400 132 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 49473741 Common - hypothetical protein BQ00570 50 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 49474152 Common - malic enzyme BQ05320 212 COG0281 SfcA, Malic enzyme Energy production and conversion 49473823 Common invB Invasion-associated protein B BQ01550 7 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 49474616 Common - hypothetical protein BQ11050 5 None None None 49474355 Common dgt deoxyguanosinetriphosphate triphosphohydrolase-like protein BQ07690 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 49474369 Common glnB Nitrogen regulatory protein p-II BQ07880 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 49474569 Common - hypothetical protein BQ10410 25 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 49473903 Common hpbC Hemin binding protein c BQ02410 15 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 49474200 Common amiB N-acetylmuramoyl-l-alanine amidase BQ05880 167 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 49473786 Common acnA aconitate hydratase BQ01090 223 COG1048 AcnA, Aconitase A Energy production and conversion 49474332 Common purB adenylosuccinate lyase BQ07450 241 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 49474138 Common trkA potassium transporter peripheral membrane component BQ05020 142 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 49474558 Common - hypothetical protein BQ10230 36 COG4091 COG4091, Predicted homoserine dehydrogenase Amino acid transport and metabolism 49474593 Common mviN Virulence factor mviN homolog BQ10690 190 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 49473758 Common rpmI 50S ribosomal protein L35 BQ00750 47 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 49474405 Common rpsJ 30S ribosomal protein S10 BQ08240 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 49474441 Common - hypothetical protein BQ08700 2 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 49474466 Pathogen - hypothetical protein BQ08980 1 None None None 49474414 Common gltL Glutamate /aspartate transport ATP-binding protein BQ08330 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 49474214 Common ubiH 2-octaprenyl-6-methoxyphenyl hydroxylase BQ06030 131 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 49474172 Common - hypothetical protein BQ05520 182 COG0759 COG0759, Uncharacterized conserved protein Function unknown 49474517 Common xseA exodeoxyribonuclease VII large subunit BQ09610 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 49473947 Common - Sodium /dicarboxylate symporter BQ03010 161 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 49474265 Pathogen - hypothetical protein BQ06660 1 None None None 49473834 Common - Sigma 54 activator homolog BQ01670 162 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 49473991 Common ubiA prenyltransferase BQ03470 193 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 49474771 Common sun2 SUN protein (FMU protein) BQ12890 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 49474024 Common - hypothetical protein BQ03860 29 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 49473809 Pathogen - hypothetical protein BQ01360 1 None None None 49474099 Common - hypothetical protein BQ04610 107 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 49474052 Common hutB Periplasmic hemin-binding protein BQ04140 115 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 49474571 Pathogen - hypothetical protein BQ10450 1 None None None 49473928 Common serC phosphoserine aminotransferase BQ02790 70 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 49473846 Common - ABC transporter, ATP-binding protein BQ01790 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 49474586 Common virB10 virB10 protein homolog BQ10610 59 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 49474480 Common ubiC chorismate pyruvate lyase BQ09210 29 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 49474247 Common topA DNA topoisomerase I BQ06420 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 49474752 Common trwE trwE protein BQ12670 59 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 49474116 Common - hypothetical protein BQ04800 45 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 49473895 Common pstB Phosphate transport system ATP-binding protein BQ02330 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 49474120 Common tpiA triosephosphate isomerase BQ04840 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 49473865 Common pnp polynucleotide phosphorylase/polyadenylase BQ01980 238 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 49474549 Common alr Alanine racemase BQ10100 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 49473756 Common ibpA1 Heat shock protein BQ00730 64 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 49474696 Pathogen - hypothetical protein BQ12090 1 None None None 49474151 Common acpP2 acyl carrier protein BQ05310 60 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 49474613 Common fdhE hypothetical protein BQ11020 28 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 49474395 Common rpsQ 30S ribosomal protein S17 BQ08140 214 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 49473964 Common glyQ glycyl-tRNA synthetase subunit alpha BQ03180 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 49474290 Common omp89 Outer membrane protein BQ06950 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 49474260 Common parE DNA topoisomerase IV subunit B BQ06610 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 49474346 Common - hypothetical protein BQ07600 14 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 49474639 Common - hypothetical protein BQ11350 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 49473969 Common thrB Isopentenyl monophosphate kinase BQ03230 169 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 49474255 Common accC acetyl-CoA carboxylase biotin carboxylase subunit BQ06530 238 COG0439 AccC, Biotin carboxylase Lipid metabolism 49473915 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase BQ02540 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 49474037 Common - Sensor histidine kinase BQ03990 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 49473983 Common ompR Transcriptional regulator ompR BQ03390 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 49474415 Common valS valyl-tRNA synthetase BQ08350 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49474576 Pathogen - hypothetical protein BQ10510 1 None None None 49474711 Common atpG F0F1 ATP synthase subunit gamma BQ12240 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 49474251 Common - hypothetical protein BQ06460 56 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 49474735 Pathogen trwL2 trwL2 protein BQ12500 1 None None None 49474232 Common - hypothetical protein BQ06270 78 COG1430 COG1430, Uncharacterized conserved protein Function unknown 49474316 Common - hypothetical protein BQ07250 27 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 49474792 Common holA DNA polymerase III subunit delta BQ13150 40 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 49474217 Common - hypothetical protein BQ06080 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 49473979 Common - hypothetical protein BQ03350 28 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 49474489 Common lpcC Lipopolysaccharide core biosynthesis mannosyltransferase lpcC BQ09300 186 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 49474782 Common - O-sialoglycoprotein endopeptidase BQ13010 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 49473810 Common badA1 Surface protein/Bartonella adhesin BQ01390 25 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 49474715 Common talC putative translaldolase BQ12290 155 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 49473725 Common - hypothetical protein BQ00410 77 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 49474603 Common pyrF Orotidine 5-phosphate decarboxylase BQ10840 66 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 49474208 Common - ATP-dependent transporter BQ05960 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 49473703 Common - ABC transporter/ATP-binding protein BQ00160 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 49474088 Common rpsF 30S ribosomal protein S6 BQ04500 203 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 49474012 Common ccrM Adenine DNA methyltransferase protein BQ03720 142 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 49474407 Common fusA elongation factor G BQ08260 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 49473873 Common - hypothetical protein BQ02060 161 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 49474304 Common sdaA L-serine dehydratase BQ07090 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 49474688 Common pgk phosphoglycerate kinase BQ11990 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 49473905 Common hbpB Hemin binding protein b BQ02430 13 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 49474295 Common tsf elongation factor Ts BQ07000 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 49474759 Common trmD tRNA (guanine-n1)-methyltransferase BQ12740 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 49474754 Common sdhB succinate dehydrogenase iron-sulfur subunit BQ12690 193 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 49473914 Common - hypothetical protein BQ02530 24 None None None 49474007 Common - Processing protease protein BQ03660 192 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 49474096 Common ksgA dimethyladenosine transferase BQ04580 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 49473858 Common - hypothetical protein BQ01910 84 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 49474079 Common pssA Phosphatidylserine synthase BQ04410 151 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 49474762 Common xerC site-specific tyrosine recombinase XerC BQ12770 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 49474279 Common gltX glutamyl-tRNA synthetase BQ06840 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 49474675 Common - hypothetical protein BQ11860 129 COG0824 FcbC, Predicted thioesterase General function prediction only 49474789 Common - Ribonuclease RNAse bn transmembrane protein BQ13120 92 COG1295 Rbn, Predicted membrane protein Function unknown 49474275 Common gor glutathione reductase BQ06800 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 49474362 Common - transport transmembrane protein BQ07790 162 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 49473789 Common dnaN DNA polymerase III subunit beta BQ01120 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 49473808 Common fruB Multiphosphoryl transfer protein (mtp) BQ01340 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 49474030 Common feuQ Sensor histidine kinase BQ03920 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 49474625 Common - phage related protein BQ11140 24 None None None 49473797 Common fabI1 enoyl-(acyl carrier protein) reductase BQ01200 222 COG0623 FabI, Enoyl- acyl-carrier-protein 49474361 Common icdA isocitrate dehydrogenase BQ07780 62 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 49473898 Common - Aminopeptidase BQ02360 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 49474606 Common - hypothetical protein BQ10950 78 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 49474585 Common virB9 virB9 protein homolog BQ10600 43 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 49474394 Common rplN 50S ribosomal protein L14 BQ08130 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 49474777 Common - hypothetical protein BQ12960 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 49474025 Common - hypothetical protein BQ03870 13 COG5436 COG5436, Predicted integral membrane protein Function unknown 49474743 Common trwK trwK protein BQ12580 65 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 49474325 Common purM phosphoribosylaminoimidazole synthetase BQ07380 227 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 49474064 Common acpS 4'-phosphopantetheinyl transferase BQ04260 153 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 49474522 Common etfA Electron transfer flavoprotein alpha-subunit BQ09680 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 49474761 Common - sapC-related protein BQ12760 26 None None None 49474432 Common htrA3 Serine protease BQ08590 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 49474105 Common - hypothetical protein BQ04680 20 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 49474828 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA BQ13560 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 49474104 Common yhjE Transport protein BQ04660 142 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 49474559 Pathogen - hypothetical protein BQ10250 1 None None None 49474674 Common tolQ Inner membrane tolQ protein BQ11850 149 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 49473730 Common dapE succinyl-diaminopimelate desuccinylase BQ00460 214 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 49474486 Common - Transcription regulator (lysr family) BQ09270 186 COG0583 LysR, Transcriptional regulator Transcription 49474162 Common ribE riboflavin synthase subunit alpha BQ05420 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 49474726 Common xthA2 Exodeoxyribonuclease III BQ12410 192 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 49474644 Pathogen - hypothetical protein BQ11420 1 None None None 49474550 Common gcvP glycine dehydrogenase BQ10110 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 49474537 Common - hypothetical protein BQ09900 76 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 49473881 Common - hypothetical protein BQ02140 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 49474632 Common - hypothetical protein BQ11240 15 None None None 49474514 Common - ABC transporter, periplasmic oligopeptide-binding protein BQ09570 204 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 49474614 Pathogen - hypothetical protein BQ11030 1 None None None 49473739 Common - Two-component sensor histidine kinase BQ00550 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 49474285 Common lpxB lipid-A-disaccharide synthase BQ06900 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 49474160 Common - hypothetical protein BQ05400 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 49473816 Common obgE GTPase ObgE BQ01460 249 COG0536 Obg, Predicted GTPase General function prediction only 49474406 Common tuf elongation factor Tu BQ08250 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 49474121 Common secG preprotein translocase subunit SecG BQ04850 6 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 49474453 Common ddl D-alanine--D-alanine ligase BQ08830 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 49473715 Common - hypothetical NADH-ubiquinone oxidoreductase BQ00300 140 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 49474310 Common rplA 50S ribosomal protein L1 BQ07160 244 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 49473794 Common cyoC Cytochrome o ubiquinol oxidase subunit III BQ01170 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 49474173 Common - hypothetical protein BQ05530 61 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 49473931 Common rpoH1 RNA polymerase factor sigma-32 BQ02820 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 49474811 Common - hypothetical protein BQ13390 49 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 49474664 Pathogen - hypothetical protein BQ11730 1 None None None 49474440 Common - hypothetical protein BQ08690 9 None None None 49474195 Common lolD Lipoprotein releasing system ATP-binding protein lolD BQ05820 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 49474465 Common - Transmembrane protein BQ08970 113 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 49474169 Common ihfA integration host factor subunit alpha BQ05490 186 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 49474772 Common - heat shock protein HtpX BQ12900 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 49474053 Common hemS Hemin degrading protein BQ04150 40 COG3720 HemS, Putative heme degradation protein Inorganic ion transport and metabolism 49473698 Common - tRNA/rRNA methyltransferase BQ00100 214 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 49474266 Common - hypothetical genomic island protein BQ06670 16 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 49474791 Pathogen - hypothetical protein BQ13140 1 None None None 49473916 Common lpxK Tetraacyldisaccharide 4 27-kinase BQ02550 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 49474094 Common - hypothetical protein BQ04560 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 49474140 Common clpX ATP-dependent protease ATP-binding subunit BQ05050 223 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 49474830 Common rho transcription termination factor Rho BQ13580 209 COG1158 Rho, Transcription termination factor Transcription 49474354 Common - hypothetical protein BQ07680 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 49474694 Common - hypothetical protein BQ12070 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 49473972 Common - hypothetical protein BQ03270 80 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 49473958 Common - hypothetical protein BQ03120 8 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 49474339 Common - hypothetical protein BQ07520 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 49473716 Common folC Folylpolyglutamate synthase BQ00310 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 49474739 Pathogen trwL6 trwL6 protein BQ12540 1 None None None 49474411 Common ybeJ Amino-acid ABC transporter binding protein BQ08300 124 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 49474809 Common - Transmembrane protein BQ13370 5 None None None 49474615 Common - hypothetical protein BQ11040 2 None None None 49474225 Common murI glutamate racemase BQ06200 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 49474651 Pathogen - hypothetical protein BQ11510 1 None None None 49474193 Common proS prolyl-tRNA synthetase BQ05800 245 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49473904 Common hbpA Hemin binding protein a BQ02420 15 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 49474201 Common mrcA2 Penicillin-binding protein 1a BQ05890 201 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 49474137 Common ntrX Nitrogen regulation protein BQ05010 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 49474594 Common trpS tryptophanyl-tRNA synthetase BQ10700 226 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 49474592 Pathogen - hypothetical protein BQ10680 1 None None None 49474368 Common uvrA excinuclease ABC subunit A BQ07870 239 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair