Lactobacillus plantarum WCFS1, complete genome NC_004567 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 28379694 Common - hypothetical protein lp_3346 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 28377168 Nonpathogen - hypothetical protein lp_0240 1 None None None 28379480 Common hpk9 histidine protein kinase; sensor protein lp_3063 11 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 28377174 Nonpathogen - hypothetical protein lp_0248 1 None None None 28379310 Common - hypothetical protein lp_2839 2 None None None 28379856 Common gutB L-iditol 2-dehydrogenase lp_3545 208 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 28379317 Common - extracellular protein lp_2847 5 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 28377561 Common nrdF ribonucleotide-diphosphate reductase subunit beta lp_0692 142 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 28378615 Common rpsU 30S ribosomal protein S21 lp_1973 115 None None None 28378351 Common - hypothetical protein lp_1659 75 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 28377284 Common gshR1 glutathione reductase lp_0369 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 28377321 Common plnC response regulator PlnC, activator lp_0417 9 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 28379497 Common - transcription regulator (putative) lp_3081 139 COG1733 COG1733, Predicted transcriptional regulators Transcription 28377797 Common asnB1 asparagine synthase (glutamine-hydrolysing) lp_0980 162 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 28377505 Common - prophage Lp1 protein 8 lp_0631 29 COG1396 HipB, Predicted transcriptional regulators Transcription 28379093 Common hisB imidazoleglycerol-phosphate dehydratase lp_2558 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 28379822 Common - transcription regulator lp_3506 44 COG2188 PhnF, Transcriptional regulators Transcription 28379693 Common nrpR4 negative regulator of proteolysis lp_3345 21 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 28379962 Common adhE bifunctional protein: alcohol dehydrogenase; acetaldehyde dehydrogenase lp_3662 188 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 28377662 Common exoA exodeoxyribonuclease III lp_0812 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 28379485 Common - extracellular protein, N-terminal fragment lp_3067 5 None None None 28379499 Common - cell surface protein, ErfK family lp_3084 8 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 28378325 Common - hypothetical protein lp_1626 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 28379222 Common purK1 phosphoribosylaminoimidazole carboxylase, ATPase subunit lp_2728 194 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 28377522 Nonpathogen - prophage Lp1 protein 26 lp_0649 1 None None None 28379001 Nonpathogen - prophage Lp2 protein 21 lp_2436 1 None None None 28377085 Common - oxidoreductase lp_0137 197 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 28379466 Common - ABC transporter, ATP-binding and permease protein lp_3042 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 28379381 Common nrdG anaerobic ribonucleotide reductase activator protein lp_2931 60 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 28378460 Common cat chloramphenicol O-acetyltransferase lp_1787 20 COG4845 COG4845, Chloramphenicol O-acetyltransferase Defense mechanisms 28378198 Common - hypothetical protein lp_1482 146 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 28378109 Nonpathogen - hypothetical protein lp_1371 1 None None None 28378744 Common - multidrug transport protein lp_2124 186 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28379656 Nonpathogen - hypothetical protein lp_3292 1 None None None 28378259 Common - integral membrane protein lp_1552 3 COG5658 COG5658, Predicted integral membrane protein Function unknown 28378430 Common - ABC transporter, ATP-binding protein lp_1750 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 28379590 Common - aminotransferase lp_3207 228 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 28377888 Common mtsA manganese ABC transporter, substrate binding protein lp_1097 168 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 28378519 Common ctpA carboxy-terminal processing proteinase lp_1864 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 28379165 Common rluA pseudouridylate synthase lp_2653 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 28377490 Common sigH DNA-directed RNA polymerase, sigma factor 30 lp_0614 22 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 28379258 Common natC2 nicotinate phosphoribosyltransferase lp_2771 123 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 28377651 Common smpB SsrA-binding protein lp_0799 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 28378219 Nonpathogen - integral membrane protein lp_1505 1 None None None 28377742 Common - 2-nitropropane dioxygenase lp_0912 142 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 28379412 Common - extracellular protein lp_2975 5 None None None 28379166 Common - transcription regulator lp_2654 13 COG1396 HipB, Predicted transcriptional regulators Transcription 28377896 Common citE citrate lyase, beta chain lp_1108 111 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 28378027 Common oppA oligopeptide ABC transporter, substrate binding protein lp_1261 178 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 28379325 Common dapE2 succinyl-diaminopimelate desuccinylase lp_2855 209 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 28377134 Common - hypothetical protein lp_0199 7 COG1396 HipB, Predicted transcriptional regulators Transcription 28379622 Nonpathogen - hypothetical protein lp_3246 1 None None None 28378566 Common - oxidoreductase lp_1918 163 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 28377989 Common cps3B glycosyltransferase lp_1216 73 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 28379926 Common srlR1 sorbitol operon transcription regulator lp_3622 18 COG3711 BglG, Transcriptional antiterminator Transcription 28377805 Common - hypothetical protein lp_0992 6 COG0789 SoxR, Predicted transcriptional regulators Transcription 28378556 Common - hypothetical protein lp_1906 30 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 28377976 Common cps2F glycosyltransferase lp_1202 211 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28378346 Common trpD anthranilate phosphoribosyltransferase lp_1654 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 28378277 Common - hypothetical protein lp_1572 9 COG4483 COG4483, Uncharacterized protein conserved in bacteria Function unknown 28379661 Common folE GTP cyclohydrolase I lp_3297 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 28378378 Common - transport protein lp_1689 178 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28378163 Common - transcription regulator lp_1442 101 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 28379935 Common - transcription regulator lp_3633 142 COG1609 PurR, Transcriptional regulators Transcription 28379512 Common - integral membrane protein lp_3099 20 COG3548 COG3548, Predicted integral membrane protein Function unknown 28377326 Common plnG bacteriocin ABC-transporter, ATP-binding and permease protein PlnG lp_0423 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 28378935 Common - ribosomal protein acetylating enzyme lp_2360 124 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 28378788 Common mtn methylthioadenosine nucleosidase; S-adenosylhomocysteine nucleosidase lp_2181 84 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 28378214 Common narH nitrate reductase, beta chain lp_1498 157 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 28378020 Common gshR2 glutathione reductase lp_1253 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 28377465 Common - transport protein (putative) lp_0584 22 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 28377736 Common bglG2 transcription antiterminator lp_0904 29 COG3711 BglG, Transcriptional antiterminator Transcription 28377731 Nonpathogen - hypothetical protein lp_0899 1 None None None 28378753 Common - N6-adenine-specific methylase (putative) lp_2134 216 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 28379330 Common sip2 signal peptidase I lp_2863 105 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 28378711 Common recJ single-strand DNA-specific exonuclease RecJ lp_2087 194 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 28379397 Common - integral membrane protein (putative) lp_2954 14 COG3641 PfoR, Predicted membrane protein, putative toxin regulator General function prediction only 28379054 Common - hypothetical protein lp_2507 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 28377109 Common dak2 dihydroxyacetone kinase, phosphatase domain dak2 lp_0169 74 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 28379676 Common - hypothetical protein lp_3321 5 None None None 28377100 Common - short-chain dehydrogenase/oxidoreductase lp_0159 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 28377479 Common pepC1 cysteine aminopeptidase lp_0601 16 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 28379891 Common agrB accesory gene regulator protein B lp_3582 4 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 28378184 Nonpathogen - hypothetical protein lp_1467 1 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 28379443 Common - extracellular protein lp_3015 15 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 28378603 Nonpathogen - hypothetical protein lp_1960 1 None None None 28379602 Nonpathogen - hypothetical protein lp_3222 1 None None None 28379123 Common pflA1 formate acetyltransferase activating enzyme lp_2596 79 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 28378191 Common fecE iron chelatin ABC transporter, ATP-binding protein lp_1475 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 28378334 Common rpsP 30S ribosomal protein S16 lp_1636 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 28378943 Common atpE H(+)-transporting two-sector ATPase, C subunit lp_2369 24 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 28377723 Common - integral membrane protein lp_0891 11 None None None 28378960 Common - ABC transporter, ATP-binding and permease protein lp_2394 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 28379760 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase lp_3431 224 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 28379549 Common - hypothetical protein lp_3142 21 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 28379551 Common - cell surface protein, ErfK family lp_3155 11 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 28379367 Common uvrA3 excinuclease ABC, subunit A lp_2915 230 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 28379083 Common npr2 NADH peroxidase lp_2544 240 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 28379767 Common - stress induced DNA binding protein (putative) lp_3441 12 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 28379704 Common - integral membrane protein lp_3359 80 COG1814 COG1814, Uncharacterized membrane protein Function unknown 28378308 Common opuB glycine betaine/carnitine/choline ABC transporter, permease protein lp_1608 185 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 28377634 Common - hypothetical protein lp_0779 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 28378677 Common - hypothetical protein lp_2044 156 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 28378449 Common - hydrolase (putative) lp_1774 8 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 28377034 Common - hypothetical protein lp_0072 35 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 28378158 Common - integral membrane protein lp_1435 9 COG4485 COG4485, Predicted membrane protein Function unknown 28377488 Common trmH tRNA/rRNA methyltransferase lp_0612 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 28378151 Common - fumarate reductase, flavoprotein subunit precursor lp_1425 219 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 28377078 Common - integral membrane protein lp_0130 4 None None None 28379593 Common - amino acid ABC transporter, ATP-binding protein lp_3211 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 28379558 Nonpathogen - transposase, fragment lp_3168 1 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 28377711 Common - bifunctional protein: amino acid aminotransferase; 2-hydroxyacid dehydrogenase lp_0874 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 28377221 Common - ABC transporter, permease protein lp_0298 34 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 28379297 Common - integral membrane protein lp_2820 16 COG3477 COG3477, Predicted periplasmic/secreted protein Function unknown 28377995 Nonpathogen cps3H polysaccharide biosynthesis protein (putative) lp_1225 2 None None None 28377202 Nonpathogen - extracellular protein lp_0277 1 None None None 28377497 Common rplJ ribosomal protein L10 lp_0621 214 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 28378285 Common glnA glutamate--ammonia ligase lp_1581 232 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 28378716 Common obgE GTPase ObgE lp_2094 249 COG0536 Obg, Predicted GTPase General function prediction only 28377148 Common - ABC transporter, ATP-binding protein lp_0215 234 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 28377156 Common - integral membrane protein lp_0224 3 None None None 28378452 Nonpathogen esbA pore-forming protein lp_1778 2 None None None 28377920 Common - hypothetical protein lp_1140 20 COG4843 COG4843, Uncharacterized protein conserved in bacteria Function unknown 28379503 Common - transcription regulator (putative) lp_3090 17 COG1309 AcrR, Transcriptional regulator Transcription 28378273 Common - integral membrane protein lp_1567 11 COG4485 COG4485, Predicted membrane protein Function unknown 28377149 Common ISP2 transposase lp_0216 25 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 28379956 Common srlR2 sorbitol operon transcription regulator lp_3656 26 COG3711 BglG, Transcriptional antiterminator Transcription 28379741 Common - transcription regulator (putative) lp_3409 33 COG1309 AcrR, Transcriptional regulator Transcription 28379423 Common gtcA3 teichoic acid glycosylation protein (putative) lp_2989 12 COG2246 COG2246, Predicted membrane protein Function unknown 28379815 Common aroD4 shikimate 5-dehydrogenase lp_3499 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 28378709 Nonpathogen - hypothetical protein lp_2085 2 None None None 28378793 Common divIVA cell division initiation protein DivIVA lp_2189 47 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 28378093 Nonpathogen - hypothetical protein lp_1351 4 None None None 28379176 Nonpathogen - hypothetical protein lp_2667 2 None None None 28378396 Common - hypothetical protein lp_1708 11 None None None 28377405 Common - hypothetical protein lp_0517 5 None None None 28378262 Common - rRNA methylase lp_1555 199 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 28377621 Common - hypothetical protein lp_0763 6 None None None 28379202 Common pyrC dihydroorotase lp_2702 216 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 28377430 Common hprT hypoxanthine-guanine phosphoribosyltransferase lp_0546 152 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 28378765 Common pdhC pyruvate dehydrogenase complex, E2 component; dihydrolipoamide S-acetyltransferase lp_2152 194 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 28379154 Common - hypothetical protein lp_2638 6 None None None 28378884 Common hexA DNA mismatch repair protein lp_2298 205 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 28377870 Common truA tRNA pseudouridine synthase A lp_1076 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 28379288 Common tyrS tyrosine--tRNA ligase lp_2807 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28378052 Common hemH ferrochelatase lp_1296 159 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 28377437 Nonpathogen - hypothetical protein lp_0554 1 None None None 28378402 Common - potassium transport protein lp_1716 31 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 28379100 Nonpathogen - hypothetical protein lp_2566 1 None None None 28378985 Common - prophage Lp2 protein 37 lp_2420 7 None None None 28378815 Common - transport protein lp_2217 205 COG0628 PerM, Predicted permease General function prediction only 28379618 Common nth2 DNA-(apurinic or apyrimidinic site) lyase lp_3241 54 COG2231 COG2231, Uncharacterized protein related to Endonuclease III DNA replication, recombination, and repair 28378459 Common - hypothetical protein lp_1786 6 COG5646 COG5646, Uncharacterized conserved protein Function unknown 28377511 Nonpathogen - prophage Lp1 protein 14 lp_0637 1 None None None 28379110 Common - acetyltransferase (putative) lp_2579 73 COG2153 ElaA, Predicted acyltransferase General function prediction only 28378505 Common hslV ATP-dependent protease peptidase subunit lp_1846 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 28378952 Common murC UDP-N-acetylmuramyl tripeptide synthase (putative) lp_2380 47 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 28378992 Nonpathogen - prophage Lp2 protein 30 lp_2427 1 None None None 28379455 Nonpathogen - integral membrane protein lp_3027 2 None None None 28379227 Common ptp3 protein-tyrosine phosphatase (putative) lp_2735 48 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 28379615 Common - hypothetical protein lp_3238 6 COG0789 SoxR, Predicted transcriptional regulators Transcription 28377753 Common - acyltransferase lp_0925 99 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 28377215 Nonpathogen - hypothetical protein lp_0292 1 None None None 28379886 Common kat catalase lp_3578 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 28379948 Common - ABC transporter, ATP-binding and permease protein lp_3647 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 28377778 Common asnC asparaginyl-tRNA synthetase lp_0956 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 28379866 Common araB L-ribulokinase (putative) lp_3556 75 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 28378136 Common dltC2 D-alanine--poly(phosphoribitol) ligase subunit 2 lp_1406 12 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 28379304 Nonpathogen - integral membrane protein lp_2828 4 COG2364 COG2364, Predicted membrane protein Function unknown 28377925 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C lp_1147 121 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 28378016 Common tagD2 glycerol-3-phosphate cytidylyltransferase lp_1248 105 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 28377767 Common - integrase lp_0941 71 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 28379539 Common bglG3 transcription antiterminator lp_3131 29 COG3711 BglG, Transcriptional antiterminator Transcription 28377675 Common galM1 aldose 1-epimerase lp_0826 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 28378806 Common mraZ hypothetical protein lp_2203 138 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 28378987 Common - prophage Lp2 protein 35 lp_2422 8 COG1783 XtmB, Phage terminase large subunit General function prediction only 28377529 Common - prophage Lp1 protein 33 lp_0656 3 None None None 28377693 Common ribC1 bifunctional protein: riboflavin kinase; FMN adenylyltransferase lp_0850 206 COG0196 RibF, FAD synthase Coenzyme metabolism 28377366 Common bla1 beta-lactamase lp_0469 15 COG2367 PenP, Beta-lactamase class A Defense mechanisms 28379578 Common - integral membrane protein lp_3192 23 COG3619 COG3619, Predicted membrane protein Function unknown 28379541 Common pts24BCA beta-glucosides PTS, EIIBCA lp_3133 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 28379109 Common - cell surface protein precursor lp_2578 51 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 28379175 Common - hypothetical protein lp_2666 6 None None None 28379355 Nonpathogen - hypothetical protein lp_2899 1 None None None 28377760 Nonpathogen - lipoprotein precursor lp_0932 3 None None None 28377941 Common pts14C cellobiose PTS, EIIC lp_1164 37 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 28379794 Common - transcription regulator lp_3478 4 COG2944 COG2944, Predicted transcriptional regulator Transcription 28377573 Common - hypothetical protein lp_0706 14 COG4467 COG4467, Uncharacterized protein conserved in bacteria Function unknown 28377051 Common - adenylyl transferase (putative) lp_0098 23 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 28379251 Common - cell-cycle regulation histidine triad protein lp_2763 205 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 28377518 Nonpathogen - prophage Lp1 protein 22 lp_0645 1 None None None 28377210 Common pts6C cellobiose PTS, EIIC lp_0286 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 28379976 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA lp_3681 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 28378578 Common - hypothetical protein lp_1931 14 COG4715 COG4715, Uncharacterized conserved protein Function unknown 28378119 Common - sodium/sulfate symport protein (putative) lp_1385 129 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 28376997 Common amy1 alpha-amylase lp_0025 163 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 28379357 Common - integral membrane protein lp_2901 95 COG1511 COG1511, Predicted membrane protein Function unknown 28377350 Nonpathogen - hypothetical protein lp_0448 3 None None None 161501981 Common cbiM cobalt transport protein CbiM lp_0102 69 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 28376988 Common proB gamma-glutamyl kinase lp_0016 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 28378373 Common - integral membrane protein lp_1684 47 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 28378914 Common - integral membrane protein lp_2334 10 None None None 28377120 Common msmK1 multiple sugar ABC transporter, ATP-binding protein lp_0180 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 28377713 Common glnQ2 glutamine ABC transporter, ATP-binding protein lp_0878 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 28378227 Common dnaI primosomal protein DnaI lp_1513 32 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 28378840 Common ack3 acetate kinase lp_2242 161 COG0282 ackA, Acetate kinase Energy production and conversion 28378828 Common - hypothetical protein lp_2230 4 None None None 28378778 Common - hypothetical protein lp_2169 7 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 28378298 Common asp3 alkaline shock protein lp_1597 38 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 28377252 Common - hypothetical protein lp_0332 215 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 28379903 Common - sugar transport protein lp_3596 164 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28378104 Nonpathogen - hypothetical protein lp_1362 1 None None None 28378443 Common - hypothetical protein lp_1766 3 None None None 28378345 Common trpG anthranilate synthase, component II lp_1653 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 28379641 Common ptp2 protein-tyrosine phosphatase lp_3272 48 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 28377117 Common malG maltose/maltodextrin ABC transporter, permease protein lp_0177 149 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 28377319 Nonpathogen plnA plantaricin A precursor peptide, induction factor lp_0415 1 None None None 28379350 Common patB aminotransferase lp_2888 220 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 28377604 Common hpk3 histidine protein kinase; sensor protein lp_0744 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 28378584 Common - hypothetical protein lp_1937 12 COG4334 COG4334, Uncharacterized protein conserved in bacteria Function unknown 28377060 Common - hypothetical protein lp_0109 67 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 28377527 Nonpathogen - prophage Lp1 protein 31 lp_0654 1 None None None 28379967 Common - acetyltransferase (putative) lp_3668 17 COG0456 RimI, Acetyltransferases General function prediction only 28377290 Nonpathogen - hypothetical protein lp_0375 1 None None None 28378950 Common prfA peptide chain release factor 1 lp_2378 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 28377910 Common cydA cytochrome D ubiquinol oxidase, subunit I lp_1125 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 28376999 Common pgmB1 beta-phosphoglucomutase lp_0027 158 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 28377016 Common - hypothetical protein lp_0053 7 None None None 28377312 Nonpathogen plnK bacteriocin precursor peptide PlnK (putative) lp_0405 1 None None None 28378901 Common mreB1 cell shape determining protein MreB lp_2319 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 28378648 Common - transposase, fragment lp_2013 4 None None None 28377304 Common - hydrolase, HAD superfamily, Cof family lp_0395 50 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28376990 Common - lipoprotein precursor, peptide binding protein OppA homolog lp_0018 159 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 28378203 Common rrp4 response regulator lp_1487 203 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 28379030 Nonpathogen - prophage Lp3 protein 10 lp_2471 1 None None None 28377545 Common - prophage Lp1 protein 50 lp_0673 25 COG5412 COG5412, Phage-related protein Function unknown 28378795 Common - cell division protein (putative) lp_2191 62 COG0762 COG0762, Predicted integral membrane protein Function unknown 28379772 Common nox5 NADH oxidase lp_3449 241 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 28379519 Common fhuG ferrichrome ABC transporter, permease protein lp_3106 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 28377277 Common accB3 acetyl-CoA carboxylase, biotin carboxyl carrier protein lp_0362 165 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 28378572 Common nox3 NADH oxidase (putative) lp_1925 243 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 28378437 Common - transport protein lp_1759 224 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28378857 Common - amino acid amidohydrolase lp_2263 167 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 28377819 Common dacB serine-type D-Ala-D-Ala carboxypeptidase lp_1010 41 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 28377967 Nonpathogen - hypothetical protein lp_1193 1 None None None 28378335 Common - hypothetical protein lp_1637 58 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 28377004 Common rrp1 response regulator lp_0036 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 28379039 Nonpathogen - hypothetical protein lp_2482 2 None None None 28377579 Common phnE1 phosphonates ABC transporter, permease protein lp_0712 114 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 28379133 Common - Na(+)/H(+) antiporter lp_2608 146 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 28378236 Common racD aspartate racemase lp_1523 76 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 28378395 Common - integral membrane protein lp_1706 5 COG2261 COG2261, Predicted membrane protein Function unknown 28377237 Common potD spermidine/putrescine ABC transporter, substrate binding protein lp_0315 133 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 28379471 Common - hypothetical protein lp_3048 6 COG1476 COG1476, Predicted transcriptional regulators Transcription 28377067 Nonpathogen - hypothetical protein lp_0118 1 None None None 28377853 Common adk adenylate kinase lp_1058 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 28379034 Nonpathogen - prophage Lp3 protein 6 lp_2475 1 None None None 28377335 Common - DNA helicase (putative) lp_0432 45 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 28377588 Common - redox-sensing transcriptional repressor Rex lp_0725 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 28377539 Nonpathogen - prophage Lp1 protein 44 lp_0667 1 None None None 28377231 Nonpathogen - integral membrane protein lp_0309 1 None None None 28377554 Nonpathogen - prophage Lp1 protein 59 lp_0682 1 None None None 28377688 Common licD lipopolysaccharide biosynthesis protein LicD lp_0844 15 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 28378863 Common - hypothetical protein lp_2269 7 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 28377520 Common - prophage Lp1 protein 24 lp_0647 16 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 28377610 Common phoU phosphate transport system protein lp_0751 193 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 28377359 Common - hypothetical protein lp_0459 18 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 28377957 Common cps1G glycosyltransferase lp_1183 147 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28379287 Common - integral membrane protein lp_2806 14 COG4720 COG4720, Predicted membrane protein Function unknown 28377846 Common rpsH 30S ribosomal protein S8 lp_1050 248 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 28378054 Common mmuM homocysteine methyltransferase lp_1298 165 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 28379582 Common - hypothetical protein lp_3197 27 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 28378593 Common - acetyltransferase (putative) lp_1947 49 COG0456 RimI, Acetyltransferases General function prediction only 28378842 Nonpathogen - hypothetical protein lp_2244 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 28378707 Common - hypothetical protein lp_2083 102 COG0393 COG0393, Uncharacterized conserved protein Function unknown 28377673 Common - hydrolase, HAD superfamily, Cof family lp_0824 106 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28379919 Common - oxidoreductase lp_3614 163 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 28378879 Common ruvA holliday junction DNA helicase RuvA lp_2287 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 28377375 Common pyrG CTP synthetase lp_0481 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 28378483 Nonpathogen - integral membrane protein lp_1815 1 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 28378598 Common - ABC transporter, permease protein lp_1955 3 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 28377332 Common plnW integral membrane protein PlnW, membrane-bound protease CAAX family lp_0429 5 None None None 28377243 Common - acetyltransferase (putative) lp_0321 10 COG0456 RimI, Acetyltransferases General function prediction only 28378114 Common - hypothetical protein lp_1377 17 COG3551 COG3551, Uncharacterized protein conserved in bacteria Function unknown 28377744 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein lp_0914 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 28378874 Common dinP DNA-damage-inducible protein P lp_2280 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 28377388 Common deoC deoxyribose-phosphate aldolase lp_0497 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 28378006 Nonpathogen - hypothetical protein lp_1237 1 None None None 28377176 Common - dihydroorotase lp_0250 26 COG3964 COG3964, Predicted amidohydrolase General function prediction only 28377783 Common recQ1 ATP-dependent DNA helicase RecQ lp_0962 232 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 28378976 Nonpathogen - prophage Lp2 protein 46 lp_2411 1 None None None 28379970 Common pepC2 cysteine aminopeptidase lp_3673 17 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 28379183 Common - transcription regulator lp_2676 19 COG0789 SoxR, Predicted transcriptional regulators Transcription 28379075 Common - DegV family protein lp_2534 49 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 28379231 Common - ABC transporter, ATP-binding protein lp_2739 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 28377270 Common rpiA2 ribose 5-phosphate epimerase lp_0354 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 28377624 Common nox2 NADH oxidase lp_0766 239 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 28379825 Common - N-acetylglucosamine kinase (putative) lp_3509 40 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 28377403 Common - hypothetical protein lp_0515 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 28379652 Common - transcription regulator lp_3287 70 COG0640 ArsR, Predicted transcriptional regulators Transcription 28377866 Common apbE1 thiamin biosynthesis lipoprotein ApbE lp_1072 132 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 28379013 Nonpathogen - prophage Lp2 protein 7 lp_2450 1 None None None 28379719 Common - prophage Lp4 protein 8, DNA primase/helicase lp_3382 26 COG3378 COG3378, Predicted ATPase General function prediction only 28378632 Common - N-methylpurine-DNA glycosylase (putative) lp_1991 84 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 28379454 Common - short-chain dehydrogenase/oxidoreductase lp_3026 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 28377827 Common - type 4 prepilin-like proteins leader peptide processing enzyme (putative) lp_1023 71 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 28378668 Common aroE 3-phosphoshikimate 1-carboxyvinyltransferase lp_2035 225 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 28379306 Common aspA aspartate ammonia-lyase lp_2830 235 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 28377228 Common - hypothetical protein lp_0306 7 None None None 28377703 Common pdx pyridoxal kinase lp_0863 30 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 28379609 Common pts27BCA beta-glucosides PTS, EIIBCA lp_3229 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28378866 Common - hypothetical protein lp_2272 4 None None None 28379243 Nonpathogen - hypothetical protein lp_2754 1 None None None 28379260 Common - ABC transporter, permease protein lp_2773 130 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 28377619 Common trxB1 thioredoxin reductase (NADPH) lp_0761 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 28379244 Nonpathogen - integral membrane protein (putative) lp_2755 1 None None None 28378836 Common - 5'-nucleotidase (putative) lp_2237 84 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 28379804 Common galR2 galactose operon repressor lp_3488 123 COG1609 PurR, Transcriptional regulators Transcription 28379252 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase lp_2764 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 28378548 Common pyk pyruvate kinase lp_1897 234 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 28379337 Common - transcription regulator lp_2871 186 COG0583 LysR, Transcriptional regulator Transcription 28379873 Common - transport protein lp_3563 135 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 28378937 Common atpC H(+)-transporting two-sector ATPase, epsilon subunit lp_2363 165 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 28379527 Nonpathogen - extracellular protein lp_3116 1 None None None 28379734 Common - transport protein lp_3402 14 COG0679 COG0679, Predicted permeases General function prediction only 28378161 Common - hypothetical protein lp_1439 23 COG3575 COG3575, Uncharacterized protein conserved in bacteria Function unknown 28377444 Common nagA N-acetylglucosamine-6-phosphate deacetylase lp_0562 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 28379021 Nonpathogen - prophage Lp3 protein 21 lp_2460 1 None None None 28378076 Common glpQ1 glycerophosphodiester phosphodiesterase lp_1328 155 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 28379117 Common - hypothetical protein lp_2589 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 28377591 Common groEL chaperonin GroEL lp_0728 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 28377841 Common rpsQ 30S ribosomal protein S17 lp_1044 232 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 28379501 Common rrp10 response regulator lp_3087 43 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 28379446 Common - ABC transporter substrate binding protein lp_3018 132 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 28378654 Common dltA D-alanine--D-alanyl carrier protein ligase lp_2019 217 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 28377681 Common nrpR1 negative regulator of proteolysis lp_0836 22 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 28378148 Common nsr nisin resistance protein (putative) lp_1420 2 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 28377094 Nonpathogen - hypothetical protein lp_0151 1 None None None 28378891 Common - zinc-dependent proteinase lp_2305 194 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 28377916 Common - prenyltransferase lp_1135 82 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 28379713 Nonpathogen - hypothetical protein lp_3375 1 None None None 28376986 Common dnaC replicative DNA helicase DnaC lp_0014 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 28378126 Nonpathogen - hypothetical protein lp_1394 1 None None None 28378688 Common ldhD D-lactate dehydrogenase lp_2057 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 28377836 Common rpsS 30S ribosomal protein S19 lp_1038 242 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 28378244 Common - hypothetical protein lp_1532 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 28378425 Common - amino acid ABC transporter, permease protein lp_1745 103 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 28378224 Common coaE dephospho-CoA kinase lp_1510 204 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 28378221 Common - integral membrane protein lp_1507 102 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 28379861 Common xpk2 putative phosphoketolase lp_3551 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 28379561 Common - transport protein lp_3171 51 COG0628 PerM, Predicted permease General function prediction only 28378492 Common - glycosyltransferase (putative) lp_1824 22 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 28379215 Common purN phosphoribosylglycinamide formyltransferase lp_2721 227 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 28379872 Common - lipase/esterase (putative) lp_3562 56 COG0657 Aes, Esterase/lipase Lipid metabolism 28379566 Common pkn2 serine/threonine protein kinase lp_3176 113 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 28379346 Common chpA cell growth regulatory protein lp_2882 33 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 28377900 Common fumC fumarate hydratase lp_1112 230 COG0114 FumC, Fumarase Energy production and conversion 28378143 Common - hypothetical protein lp_1415 17 COG3679 COG3679, Uncharacterized conserved protein Function unknown 28378617 Common - short-chain dehydrogenase/oxidoreductase lp_1975 193 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 28378781 Common - cell surface protein precursor lp_2174 8 None None None 28377088 Nonpathogen - extracellular protein lp_0141 1 None None None 28378768 Common def peptide deformylase lp_2155 206 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 28378523 Common - DegV family protein lp_1868 52 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 28378512 Nonpathogen - hypothetical protein lp_1855 1 None None None 28377297 Nonpathogen - hypothetical protein lp_0384 2 None None None 28379627 Common - acetyltransferase (putative) lp_3252 84 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 28378131 Common pts15B beta-glucosides PTS, EIIB lp_1399 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 28377598 Common - ribosomal protein S30EA lp_0737 178 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 28378083 Common - ABC transporter, ATP-binding protein lp_1336 179 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28377530 Nonpathogen - prophage Lp1 protein 35 lp_0658 1 None None None 28377463 Common npsC 4'-phosphopantetheinyl transferase lp_0582 5 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 28378046 Common - adenine phosphoribosyltransferase lp_1289 7 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 28379210 Nonpathogen - hypothetical protein lp_2715 3 None None None 28379785 Common lacS1 lactose transport protein lp_3468 86 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 28376978 Common recF recombination protein F lp_0005 165 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 28377259 Common - transaminase lp_0339 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 28377264 Common - transcription regulator (putative) lp_0347 15 COG1695 COG1695, Predicted transcriptional regulators Transcription 28378720 Common - lipoprotein precursor lp_2098 13 COG1409 Icc, Predicted phosphohydrolases General function prediction only 28377815 Common - acetyltransferase (putative) lp_1003 97 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 28379329 Common sip1 signal peptidase I lp_2862 166 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 28379707 Common copB copper transporting ATPase lp_3363 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 28378411 Common map3 maltose phosphorylase lp_1730 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 28377328 Nonpathogen plnS plantaricin biosynthesis protein PlnS lp_0424a 1 None None None 28379668 Common ISP1 transposase lp_3308 49 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28378102 Common - membrane-bound protease, CAAX family lp_1359 23 None None None 28379435 Common - transcription regulator lp_3006 6 COG1396 HipB, Predicted transcriptional regulators Transcription 28378048 Nonpathogen - hypothetical protein lp_1291 1 None None None 28379802 Common lacS2 sugar transport protein lp_3486 87 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 28377424 Common mfd transcription-repair coupling factor lp_0539 236 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 28379457 Common - oxidoreductase (putative) lp_3029 23 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 28378279 Common - hypothetical protein lp_1574 3 COG3340 PepE, Peptidase E Amino acid transport and metabolism 28377544 Nonpathogen - prophage Lp1 protein 49 lp_0672 1 None None None 28379773 Common - extracellular protein lp_3450 4 None None None 28379743 Common - extracellular protein lp_3411 11 COG4086 COG4086, Predicted secreted protein Function unknown 28379308 Common - 2-haloacid dehalogenase (putative) lp_2835 33 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 28379246 Common thrC threonine synthase lp_2758 132 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 28379056 Common - transport protein lp_2509 62 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 28377786 Common - integral membrane protein lp_0966 8 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 28379399 Common wapA cell surface protein precursor lp_2958 5 COG5099 COG5099, RNA-binding protein of the Puf family, translational repressor Translation, ribosomal structure and biogenesis 28379843 Common map4 maltose phosphorylase lp_3530 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 28379700 Nonpathogen - hypothetical protein lp_3353 1 None None None 28378423 Nonpathogen - hypothetical protein lp_1742 1 None None None 28379332 Common - acetyltransferase (putative) lp_2865 22 COG0456 RimI, Acetyltransferases General function prediction only 28379195 Common rexB ATP-dependent nuclease, subunit B lp_2694 23 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 28376975 Common dnaA chromosomal replication initiation protein DnaA lp_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 28379975 Common - extracellular protein lp_3679 7 None None None 28379383 Nonpathogen - lipoprotein precursor lp_2934 1 None None None 28377028 Common pgmB2 beta-phosphoglucomutase lp_0066 168 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 28378117 Common - exopolyphosphatase-related protein (putative) lp_1380 75 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 28379827 Common pbg8 6-phospho-beta-glucosidase lp_3512 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 28378081 Common - ABC transporter, permease protein lp_1334 5 None None None 28379390 Common - transport protein lp_2943 89 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 28379597 Common - integral membrane protein (putative) lp_3217 5 COG4709 COG4709, Predicted membrane protein Function unknown 28379933 Common - alpha-mannosidase (putative) lp_3631 42 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 28378264 Common - transcription regulator (putative) lp_1557 127 COG1733 COG1733, Predicted transcriptional regulators Transcription 28379136 Nonpathogen - ABC transporter, permease protein lp_2613 2 None None None 28379008 Nonpathogen - prophage Lp2 protein 12 lp_2445 1 None None None 28378332 Common - hypothetical protein lp_1634 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 28379514 Common - transport protein lp_3101 182 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28379360 Common endA DNA-entry nuclease lp_2906 6 None None None 28378786 Common - hypothetical protein lp_2179 7 None None None 28379085 Common - integral membrane protein lp_2549 134 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 28378601 Common - ABC transporter, ATP-binding protein lp_1958 248 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28377188 Common treR transcription regulator lp_0262 96 COG2188 PhnF, Transcriptional regulators Transcription 28379044 Nonpathogen - hypothetical protein lp_2488 1 None None None 28377066 Common - hypothetical protein lp_0117 120 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 28377090 Common - oxidoreductase lp_0146 176 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 28379702 Common - acetyltransferase (putative) lp_3356 82 COG2153 ElaA, Predicted acyltransferase General function prediction only 28378469 Common - acetyltransferase (putative) lp_1797 45 COG2153 ElaA, Predicted acyltransferase General function prediction only 28378193 Common - flavodoxin lp_1477 76 COG0716 FldA, Flavodoxins Energy production and conversion 28379266 Common pts20B cellobiose PTS, EIIB lp_2781 28 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 28379547 Nonpathogen - integral membrane protein (putative) lp_3139 2 COG3152 COG3152, Predicted membrane protein Function unknown 28378212 Common moeB molybdopterin biosynthesis protein MoeB lp_1496 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 28378839 Common - amino acid transport protein lp_2240 122 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 28379312 Common - integral membrane protein lp_2841 119 COG2855 COG2855, Predicted membrane protein Function unknown 28379319 Common - ABC transporter, ATP-binding protein lp_2849 249 COG4152 COG4152, ABC-type uncharacterized transport system, ATPase component General function prediction only 28378170 Common - extracellular protein lp_1450 6 None None None 28377282 Common choS glycine betaine/carnitine/choline ABC transporter, substrate binding and permease protein lp_0367 126 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 28378957 Common bcaT branched-chain amino acid aminotransferase lp_2390 191 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 28379327 Common nth1 DNA-(apurinic or apyrimidinic site) lyase lp_2860 237 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 28379450 Nonpathogen - hypothetical protein lp_3022 1 None None None 28379470 Nonpathogen - hypothetical protein lp_3047 2 None None None 28379831 Common metC2 cystathionine beta-lyase lp_3517 227 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 28377492 Common secE preprotein translocase subunit SecE lp_0616 5 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 28379314 Common tagE5 poly(glycerol-phosphate) alpha-glucosyltransferase lp_2843 178 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28379964 Common padR regulator of phenolic acid metabolism PadR lp_3664 55 COG1695 COG1695, Predicted transcriptional regulators Transcription 28379271 Common - hydrolase, HAD superfamily, Cof family lp_2787 119 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28379278 Common - cell surface protein precursor lp_2795 19 None None None 28377499 Common - prophage Lp1 protein 1, integrase lp_0624 56 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 28379483 Common - cell surface protein precursor lp_3066 8 None None None 28379163 Common - transcription regulator lp_2651 117 COG2188 PhnF, Transcriptional regulators Transcription 28379709 Nonpathogen - hypothetical protein lp_3366 1 None None None 28379068 Common - protein containing diguanylate cyclase/phosphodiesterase domain 1 (GGDEF) lp_2524 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 28379925 Common srlM1 sorbitol operon activator lp_3621 15 COG4578 GutM, Glucitol operon activator Transcription 28379477 Nonpathogen - cell surface protein precursor lp_3059 4 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 28378723 Nonpathogen cps4H polysaccharide polymerase lp_2101 1 None None None 28377441 Common - cation transport protein lp_0558 51 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 28378367 Common fabZ2 (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase lp_1677 169 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 28377660 Common - acetyltransferase (putative) lp_0810 34 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 28378404 Nonpathogen - lipoprotein precursor (putative) lp_1718 1 None None None 28379490 Common - extracellular protein lp_3073 6 None None None 28379256 Common - transport protein lp_2768 18 None None None 28378727 Common galE3 UDP-glucose 4-epimerase lp_2105 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28379414 Common - cell surface protein precursor lp_2977 8 None None None 28378513 Common - hypothetical protein lp_1856 39 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 28378696 Common mvaS hydroxymethylglutaryl-CoA synthase lp_2067 51 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 28378257 Common sbcC exonuclease SbcC lp_1548 106 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 28379236 Nonpathogen - ABC transporter, permease protein lp_2744 2 None None None 28378324 Common - hypothetical protein lp_1625 33 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 28378268 Common udk uridine kinase lp_1562 78 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 28379415 Nonpathogen - extracellular protein lp_2978 1 None None None 28379571 Nonpathogen - transport protein lp_3183 3 COG0730 COG0730, Predicted permeases General function prediction only 28378134 Common - transport protein lp_1402 18 None None None 28379135 Common - pyrazinamidase/nicotinamidase lp_2612 133 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 28377751 Common - cell surface protein precursor lp_0923 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 28377217 Common - transcription regulator (putative) lp_0294 18 COG1309 AcrR, Transcriptional regulator Transcription 28378804 Common ftsL cell division protein FtsL (putative) lp_2201 6 COG4839 FtsL, Protein required for the initiation of cell division Cell division and chromosome partitioning 28378849 Common - hypothetical protein lp_2254 21 COG1416 COG1416, Uncharacterized conserved protein Function unknown 28377364 Common purR purine operon repressor lp_0466 102 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 28379576 Common hpk11 histidine protein kinase; sensor protein lp_3190 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 28378994 Nonpathogen - prophage Lp2 protein 28 lp_2429 1 None None None 28379225 Common - oxidoreductase (putative) lp_2733 114 COG0431 COG0431, Predicted flavoprotein General function prediction only 28378817 Common - hypothetical protein lp_2219 61 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 28377762 Common - hypothetical protein lp_0935 3 None None None 28379220 Common purS conserved purine biosynthesis cluster protein lp_2726 99 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 28379229 Common - cell surface hydrolase, membrane-bound (putative) lp_2737 8 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 28378457 Common pyrAA2 carbamoyl phosphate synthase small subunit lp_1783 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 28379881 Common - oxidoreductase lp_3572 234 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 28379375 Common - transcription regulator lp_2924 70 COG2188 PhnF, Transcriptional regulators Transcription 28377927 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B lp_1149 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 28378217 Nonpathogen - hypothetical protein lp_1502 1 None None None 28379353 Common - ABC transporter, ATP-binding and permease protein lp_2893 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 28377582 Common phnD phosphonates ABC transporter, substrate binding protein (putative) lp_0715 52 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 28379778 Common - transcription regulator (putative) lp_3458 69 COG1309 AcrR, Transcriptional regulator Transcription 28378731 Common uvrC excinuclease ABC subunit C lp_2109 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 28378529 Common dapB dihydrodipicolinate reductase lp_1874 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 28379565 Common - integral membrane protein lp_3175 5 None None None 28377031 Common ptp1 protein-tyrosine phosphatase lp_0069 50 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 28379495 Common - transcription regulator (putative) lp_3079 57 COG1695 COG1695, Predicted transcriptional regulators Transcription 28378146 Common - hypothetical protein lp_1418 47 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 28377323 Nonpathogen plnI immunity protein PlnI, membrane-bound protease CAAX family lp_0419 2 COG4449 COG4449, Predicted protease of the Abi (CAAX) family General function prediction only 28377575 Common fat oleoyl-[acyl-carrier protein] thioesterase (putative) lp_0708 22 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 28377102 Common - ABC transporter, permease protein lp_0161 18 COG3559 TnrB3, Putative exporter of polyketide antibiotics Cell envelope biogenesis, outer membrane 28379171 Common - transcription regulator (putative) lp_2662 108 COG2606 EbsC, Uncharacterized conserved protein Function unknown 28377289 Common - extracellular protein lp_0374 4 None None None 28377639 Common clpP ATP-dependent Clp protease proteolytic subunit lp_0786 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 28378718 Common fruK 1-phosphofructokinase lp_2096 100 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 28379107 Common - integral membrane protein lp_2574 38 COG3548 COG3548, Predicted integral membrane protein Function unknown 28379809 Common aroD 3-dehydroquinate dehydratase lp_3493 55 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 28377454 Common thrB homoserine kinase lp_0572 122 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 28378360 Common fabZ1 (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase lp_1670 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 28378844 Common comGC ComG operon protein 3 precursor lp_2247 22 COG4537 ComGC, Competence protein ComGC Intracellular trafficking and secretion 28379950 Common - transcription regulator lp_3649 122 COG1609 PurR, Transcriptional regulators Transcription 28379635 Common glyK glycerate kinase lp_3266 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 28378967 Nonpathogen - prophage Lp2 protein 55 lp_2402 1 None None None 28378391 Common - integral membrane protein lp_1702 27 COG3152 COG3152, Predicted membrane protein Function unknown 28377166 Nonpathogen - integral membrane protein lp_0237 1 None None None 28378398 Common pepD4 dipeptidase lp_1711 25 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 28379738 Nonpathogen - hypothetical protein lp_3406 1 None None None 28378306 Common recN DNA repair protein RecN lp_1605 202 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 28378623 Common hisS histidyl-tRNA synthetase lp_1981 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28377568 Common recR recombination protein RecR lp_0700 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 28377154 Common - oxidoreductase lp_0221 167 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 28378283 Common miaA tRNA isopentenyltransferase lp_1579 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 28378908 Common csd3 cysteine desulfurase lp_2326 236 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 28377483 Common radA DNA repair protein RadA lp_0606 206 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 28377071 Common hpo halo peroxidase lp_0122 119 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 28378675 Common - hypothetical protein lp_2042 35 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 28378546 Common - hypothetical protein lp_1893 40 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 28377058 Common - NCAIR mutase, PurE-related protein lp_0105 64 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 28378625 Common - hypothetical protein lp_1983 70 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 28379654 Common - transcription regulator lp_3290 10 COG1396 HipB, Predicted transcriptional regulators Transcription 28378589 Common hpk6 histidine protein kinase; sensor protein lp_1943 133 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 28379813 Common - transport protein lp_3497 11 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377146 Common - integral membrane protein lp_0213 88 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 28377310 Nonpathogen plnR plantaricin biosynthesis protein PlnR lp_0403 1 None None None 28378450 Common - oxidoreductase lp_1776 55 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 28379554 Common - transport protein lp_3160 196 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377432 Common hsp33 heat shock protein HSP33 lp_0548 133 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 28378058 Common - multidrug transport protein lp_1302 231 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28378275 Common fthC 5-formyltetrahydrofolate cyclo-ligase lp_1570 133 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 28378700 Common - transposase, fragment lp_2074 5 None None None 28378066 Common leuS leucyl-tRNA synthetase lp_1316 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28377733 Common pgm4 phosphoglycerate mutase lp_0901 166 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 28377407 Common rhe1 ATP-dependent RNA helicase lp_0520 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 28378798 Common ftsA cell division protein FtsA lp_2194 185 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 28377668 Common - hypothetical protein lp_0818 74 COG1624 COG1624, Uncharacterized conserved protein Function unknown 28379299 Common - ABC transporter, ATP-binding protein lp_2823 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 28379958 Common rbsU ribose transport protein lp_3658 11 COG4975 GlcU, Putative glucose uptake permease Carbohydrate transport and metabolism 28378376 Common - GTPase lp_1687 163 COG1162 COG1162, Predicted GTPases General function prediction only 28379894 Common pox4 pyruvate oxidase lp_3587 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 28377439 Common - hypothetical protein lp_0556 36 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 28377208 Nonpathogen - hypothetical protein lp_0284 1 None None None 28379756 Common - hypothetical protein lp_3426 6 COG4367 COG4367, Uncharacterized protein conserved in bacteria Function unknown 28378661 Common grpE heat shock protein GrpE lp_2028 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 28379461 Common - short-chain dehydrogenase/oxidoreductase lp_3033 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 28379204 Common pyrR1 pyrimidine regulatory protein PyrR lp_2704 111 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 28378882 Nonpathogen - hypothetical protein lp_2292 1 None None None 28379556 Common - transcription regulator (putative) lp_3164 12 COG1309 AcrR, Transcriptional regulator Transcription 28378763 Common - hypothetical protein lp_2149 11 COG4476 COG4476, Uncharacterized protein conserved in bacteria Function unknown 28377894 Common citC [citrate (pro-3S)-lyase] ligase lp_1106 25 COG3053 CitC, Citrate lyase synthetase Energy production and conversion 28377803 Common - hypothetical protein lp_0990 7 None None None 28377875 Common - malate / lactate dehydrogenase lp_1082 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 28377844 Common rplE 50S ribosomal protein L5 lp_1047 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 28379157 Common lplA1 lipoate-protein ligase lp_2643 76 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 28379040 Nonpathogen - hypothetical protein lp_2483 1 None None None 28378595 Common - integral membrane protein lp_1949 14 COG2364 COG2364, Predicted membrane protein Function unknown 28377931 Common - cation transporting P-type ATPase lp_1154 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 28378314 Common dfp pantothenate metabolism flavoprotein Dfp lp_1614 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 28377552 Nonpathogen - prophage Lp1 protein 57 lp_0680 1 None None None 28379941 Common - integral membrane protein lp_3640 6 COG5578 COG5578, Predicted integral membrane protein Function unknown 28378809 Common ftsK2 cell division protein FtsK lp_2210 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 28379362 Common - acetyltransferase (putative) lp_2909 81 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 28377026 Common - hypothetical protein lp_0063 20 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 28379761 Common - hypothetical protein lp_3432 10 COG1434 COG1434, Uncharacterized conserved protein Function unknown 28378924 Common - oxidoreductase lp_2346 167 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 28379285 Common - oxidoreductase lp_2803 186 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 28379036 Nonpathogen - prophage Lp3 protein 4 lp_2477 1 None None None 28379120 Common rnh ribonuclease H (putative) lp_2593 179 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 28377414 Common argC2 N-acetyl-gamma-glutamyl-phosphate reductase lp_0528 197 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 28377817 Common als acetolactate synthase lp_1005 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 28378455 Common rluD1 pseudouridylate synthase lp_1781 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 28377377 Nonpathogen - hypothetical protein lp_0483 1 None None None 28378558 Common drrB ABC transporter, permease protein lp_1909 146 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 28378996 Common - prophage Lp2 protein 26 lp_2431 6 None None None 28378337 Common trmD tRNA (guanine-N1-)-methyltransferase lp_1639 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 28379051 Common - hypothetical protein lp_2504 23 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 28377233 Common - acetyltransferase (putative) lp_0311 67 COG2153 ElaA, Predicted acyltransferase General function prediction only 28378941 Common atpH H(+)-transporting two-sector ATPase, delta subunit lp_2367 177 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 28377193 Common tagD1 glycerol-3-phosphate cytidylyltransferase lp_0267 99 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 28377337 Common trpS tryptophanyl-tRNA synthetase II lp_0434 248 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28378861 Common xtp1 xanthosine triphosphate pyrophosphatase lp_2267 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 28378382 Nonpathogen - transcription regulator, C-terminal fragment (putative) lp_1693a 1 None None None 28377503 Nonpathogen - prophage Lp1 protein 6 lp_0629 1 None None None 28377949 Common glpF4 glycerol uptake facilitator protein lp_1175 77 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 28379917 Common iolG4 myo-inositol 2-dehydrogenase lp_3612 181 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 28379463 Common ISP1 transposase lp_3036 49 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28379032 Common - prophage Lp3 protein 8, helicase lp_2473 32 COG5545 COG5545, Predicted P-loop ATPase and inactivated derivatives General function prediction only 28377822 Common ctsR transcription regulator lp_1018 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 28378577 Common - oxidoreductase (putative) lp_1930 9 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 28377045 Common - cation efflux protein (putative) lp_0085 148 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 28377788 Common - integral membrane protein lp_0968 28 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 28377653 Common glnPH1 glutamine ABC transporter, substrate binding and permease protein lp_0802 178 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 28377343 Common - sugar kinase and transcription regulator lp_0441 116 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 28378229 Common infC translation initiation factor IF-3 lp_1515 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 28378646 Common - hypothetical protein lp_2010 8 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 28379900 Common rhaA L-rhamnose isomerase lp_3593 23 COG4806 RhaA, L-rhamnose isomerase Carbohydrate transport and metabolism 28378036 Common ptsI phosphoenolpyruvate--protein phosphatase lp_1274 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 28379066 Nonpathogen - hypothetical protein lp_2522 1 None None None 28378916 Common - bifunctional glutamate--cysteine ligase/glutathione synthetase lp_2336 93 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 28377626 Common - multidrug transport protein lp_0770 223 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377348 Common ppx1 exopolyphosphatase lp_0446 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 28376995 Common glgA starch (bacterial glycogen) synthase lp_0023 149 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 28378435 Common - hypothetical protein lp_1756 133 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 28379969 Common - transcription regulator lp_3672 10 COG1396 HipB, Predicted transcriptional regulators Transcription 28377069 Common - amino acid transport protein lp_0120 143 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 28378164 Nonpathogen - transcription regulator lp_1443 7 COG1309 AcrR, Transcriptional regulator Transcription 28378357 Nonpathogen - integral membrane protein lp_1667 1 None None None 28378826 Common nrpR3 negative regulator of proteolysis lp_2228 53 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 28377809 Common cspC cold shock protein CspC lp_0997 182 COG1278 CspC, Cold shock proteins Transcription 28379077 Common metY O-acetylhomoserine (thiol)-lyase lp_2536 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 28377212 Nonpathogen - hypothetical protein lp_0289 1 None None None 28377395 Common sdhA L-serine dehydratase, alpha subunit lp_0506 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 28379373 Common npp nucleotide pyrophosphatase (putative) lp_2922 35 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 28378850 Nonpathogen - hypothetical protein lp_2255 1 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 28379011 Common - prophage Lp2 protein 9 lp_2448 24 COG1396 HipB, Predicted transcriptional regulators Transcription 28377525 Nonpathogen - prophage Lp1 protein 29 lp_0652 1 None None None 28379670 Common - esterase (putative) lp_3312 121 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 28377708 Nonpathogen - extracellular protein lp_0869 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 28378021 Common prfC peptide chain release factor 3 lp_1255 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 28378059 Nonpathogen sdr cell surface SD repeat protein precursor lp_1303a 1 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 28379025 Common - prophage Lp3 protein 17, portal protein lp_2464 34 COG4695 COG4695, Phage-related protein Function unknown 28377790 Common - acetyltransferase (putative) lp_0970 30 COG0456 RimI, Acetyltransferases General function prediction only 28377965 Nonpathogen - transposase, fragment lp_1191 2 None None None 28379537 Nonpathogen - hypothetical protein lp_3129 1 None None None 28378586 Common - oxidoreductase lp_1939 204 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 28378176 Common - hypothetical protein lp_1457 9 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 28379599 Common pts24BCA sucrose PTS, EIIBCA lp_3219 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28377014 Common pnb p-nitrobenzoate reductase lp_0050 53 COG0778 NfnB, Nitroreductase Energy production and conversion 28377701 Common - amino acid transport protein (putative) lp_0861 192 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 28377352 Common - hypothetical protein lp_0450 69 COG1801 COG1801, Uncharacterized conserved protein Function unknown 28379262 Common dsdA D-serine dehydratase lp_2776 135 COG3048 DsdA, D-serine dehydratase Amino acid transport and metabolism 28378201 Nonpathogen - hypothetical protein lp_1485 1 None None None 28378704 Common rodA1 rod-shape determining protein lp_2078 204 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 28379186 Common gpd glucose-6-phosphate 1-dehydrogenase lp_2681 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 28377115 Common malE maltose/maltodextrin ABC transporter, substrate binding protein lp_0175 81 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 28378350 Common trpA tryptophan synthase subunit alpha lp_1658 214 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 28379129 Common ccpB catabolite control protein B lp_2602 127 COG1609 PurR, Transcriptional regulators Transcription 28377738 Common pbg2 6-phospho-beta-glucosidase lp_0906 102 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 28379196 Common - integral membrane protein lp_2696 60 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 28379620 Common - oxidoreductase (putative) lp_3244 117 COG0431 COG0431, Predicted flavoprotein General function prediction only 28377903 Common mleR2 malolactic regulator (putative) lp_1115 168 COG0583 LysR, Transcriptional regulator Transcription 28379238 Common gtcA2 teichoic acid glycosylation protein lp_2747 11 COG2246 COG2246, Predicted membrane protein Function unknown 28377470 Common accB1 acetyl-CoA carboxylase, biotin carboxyl carrier protein lp_0589 100 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 28378246 Common - hypothetical protein lp_1534 27 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 28378834 Common - sugar phosphatase of the HAD superfamily (putative) lp_2235 104 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 28378239 Common - hydrolase, HAD superfamily lp_1527 43 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 28377383 Common - hypothetical protein lp_0490 14 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 28377081 Common - transcription regulator lp_0133 31 COG0640 ArsR, Predicted transcriptional regulators Transcription 28379780 Common - hypothetical protein lp_3460 12 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 28377644 Common tpiA triosephosphate isomerase lp_0791 217 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 28379791 Common - sugar transport protein lp_3474 82 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377917 Common - oxidoreductase (putative) lp_1136 145 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 28378141 Nonpathogen - hypothetical protein lp_1412 1 None None None 28378498 Common - putative manganese-dependent inorganic pyrophosphatase lp_1837 56 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 28378824 Common coiA competence protein lp_2226 15 COG4469 CoiA, Competence protein General function prediction only 28377826 Common rpoC DNA-directed RNA polymerase subunit beta' lp_1022 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 28378652 Common dltC1 D-alanine--poly(phosphoribitol) ligase subunit 2 lp_2017 12 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 28378897 Common minD septum site-determining protein MinD lp_2315 155 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 28377275 Common - transcription regulator (putative) lp_0360 30 COG1959 COG1959, Predicted transcriptional regulator Transcription 28377096 Common - hypothetical protein lp_0154 5 COG1695 COG1695, Predicted transcriptional regulators Transcription 28379400 Common - transport protein lp_2959 125 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 28379385 Common apbE2 thiamin biosynthesis lipoprotein ApbE lp_2936 126 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 28379269 Common pgm7 phosphoglycerate mutase lp_2785 121 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 28378375 Common - acyl-CoA thioester hydrolase (putative) lp_1686 79 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 28378186 Common - ABC transporter component (putative) lp_1469 182 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 28379213 Common purD phosphoribosylamine--glycine ligase lp_2719 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 28378774 Common - extracellular protein, gamma-D-glutamate-meso-diaminopimelate muropeptidase (putative) lp_2162 115 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 28377295 Nonpathogen - integral membrane protein lp_0382 1 None None None 28377537 Common - prophage Lp1 protein 42 lp_0665 6 None None None 28379787 Common lacR transcription regulator of beta-galactosidase gene lp_3470 111 COG1609 PurR, Transcriptional regulators Transcription 28378127 Nonpathogen - hypothetical protein lp_1395 1 None None None 28377864 Common ndh2 NADH dehydrogenase lp_1069 167 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 28378485 Common - ribitol-5-phosphate 2-dehydrogenase (putative) lp_1817 32 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 28378872 Common rhe3 ATP-dependent RNA helicase lp_2278 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 28377960 Common rfbA glucose-1-phosphate thymidylyltransferase lp_1186 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 28378930 Common gcsH2 glycine cleavage system, H protein lp_2353 178 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 28378112 Common metH bifunctional homocysteine S-methyltransferase/5,10-methylenetetrahydrofolate reductase protein lp_1374 176 COG0646 MetH, Methionine synthase I (cobalamin-dependent), methyltransferase domain Amino acid transport and metabolism 28378120 Common - cation efflux protein (putative) lp_1386 162 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 28378296 Common pepP Xaa-Pro aminopeptidase (putative) lp_1595 239 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 28379525 Common - cell surface protein precursor lp_3114 23 None None None 28378486 Common tagB1 teichoic acid biosynthesis protein lp_1818 20 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 28377122 Common - mannosyl-glycoprotein endo-beta-N-acetylglucosaminidase lp_0182 33 COG4724 COG4724, Endo-beta-N-acetylglucosaminidase D Carbohydrate transport and metabolism 28377781 Nonpathogen - hypothetical protein lp_0960 1 None None None 28379407 Common - nitroreductase lp_2968 38 COG0778 NfnB, Nitroreductase Energy production and conversion 28377934 Common - transcription regulator lp_1157 86 COG1737 RpiR, Transcriptional regulators Transcription 28377074 Common - stress-responsive transcription regulator (putative) lp_0126 22 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 28377691 Common - transport protein lp_0848 137 COG2252 COG2252, Permeases General function prediction only 28378343 Common - ABC transporter, permease protein lp_1649 3 None None None 28378478 Common - integral membrane protein lp_1809 23 COG2035 COG2035, Predicted membrane protein Function unknown 28378766 Common pdhB pyruvate dehydrogenase complex, E1 component, beta subunit lp_2153 202 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 28378491 Nonpathogen - integral membrane protein lp_1823 1 None None None 28379185 Nonpathogen - integral membrane protein lp_2680 1 None None None 28377837 Common rplV 50S ribosomal protein L22 lp_1039 221 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 28378008 Nonpathogen - hypothetical protein lp_1239 1 None None None 28379339 Common adh2 alcohol dehydrogenase lp_2873 205 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 28379736 Common - integral membrane protein lp_3404 32 COG2966 COG2966, Uncharacterized conserved protein Function unknown 28379650 Common qacH quaternary ammonium compound-resistance protein lp_3285 123 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 28378783 Common ktrA potassium uptake protein lp_2176 121 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 28378508 Common topA DNA topoisomerase I lp_1850 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 28378974 Common - prophage Lp2 protein 48 lp_2409 18 COG5412 COG5412, Phage-related protein Function unknown 28378194 Common moaE molybdopterin biosynthesis protein, E chain lp_1478 152 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 28377258 Common - hypothetical protein lp_0338 14 COG4357 COG4357, Uncharacterized conserved protein Function unknown 28377746 Common - transcription regulator lp_0917 12 COG1396 HipB, Predicted transcriptional regulators Transcription 28378252 Common gnd2 6-phosphogluconate dehydrogenase lp_1541 183 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 28379607 Nonpathogen - hypothetical protein lp_3227 1 None None None 28378698 Nonpathogen - hypothetical protein lp_2069 1 None None None 28378686 Common rpsB 30S ribosomal protein S2 lp_2055 247 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 28379146 Nonpathogen - acetyltransferase (putative) lp_2625 1 None None None 28379115 Common - cell surface hydrolase, membrane-bound (putative) lp_2586 10 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 28378531 Common - hypothetical protein lp_1877 80 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 28377422 Common ldhL1 L-lactate dehydrogenase lp_0537 175 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 28377612 Common - integral membrane protein lp_0753 8 COG1950 COG1950, Predicted membrane protein Function unknown 28377628 Common uvrB excinuclease ABC subunit B lp_0772 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 28379145 Nonpathogen - hypothetical protein lp_2624 1 COG3506 COG3506, Uncharacterized conserved protein Function unknown 28379875 Common - hypothetical protein lp_3566 13 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 28378889 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase lp_2303 205 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 28376984 Common - exopolyphosphatase-related protein (putative) lp_0012 88 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 28379191 Common - transcription regulator lp_2689 153 COG0583 LysR, Transcriptional regulator Transcription 28378078 Common mscL large-conductance mechanosensitive channel lp_1330 140 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 28377446 Common tagA teichoic acid biosynthesis protein A lp_0564 112 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 28379715 Common - prophage Lp4 protein 12 lp_3378 2 None None None 28378705 Nonpathogen - hypothetical protein lp_2081 1 None None None 28377172 Common - transcription regulator lp_0245 115 COG2188 PhnF, Transcriptional regulators Transcription 28377600 Nonpathogen prfB-N peptide chain release factor 2, N-terminal fragment lp_0740 1 None None None 28377169 Common ndk nucleoside-diphosphate kinase lp_0242 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 28378846 Common comGA ComG operon protein 1 lp_2249 205 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 28378456 Common pyrR2 pyrimidine regulatory protein PyrR lp_1782 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 28378289 Nonpathogen - hypothetical protein lp_1586 1 None None None 28377056 Common - transcription regulator lp_0103 17 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 28378270 Common - integral membrane protein lp_1564 4 None None None 28378888 Common cinA competence-damage protein lp_2302 213 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 28378697 Nonpathogen - hypothetical protein lp_2068 1 None None None 28378533 Nonpathogen - hypothetical protein lp_1880 1 None None None 28378250 Common - lipoprotein precursor lp_1539 13 COG3212 COG3212, Predicted membrane protein Function unknown 28377971 Common cps2A exopolysaccharide biosynthesis protein lp_1197 24 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 28377640 Common rpoN RNA polymerase factor sigma-54 lp_0787 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 28378090 Nonpathogen - hypothetical protein lp_1347 5 COG2267 PldB, Lysophospholipase Lipid metabolism 28378157 Common - MutT/NudX family protein (putative) lp_1433 3 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 28379291 Common - hypothetical protein lp_2812 5 COG4990 COG4990, Uncharacterized protein conserved in bacteria Function unknown 28378362 Common acpA2 acyl carrier protein lp_1672 22 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 28379292 Common - hypothetical protein lp_2813 4 COG5506 COG5506, Uncharacterized conserved protein Function unknown 28379535 Common - cell surface protein precursor, GY family lp_3127 14 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 28378322 Common - hypothetical protein lp_1622 34 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 28379841 Common pts33BCA beta-glucosides PTS, EIIBCA lp_3527 61 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28379430 Common - ABC transporter, ATP-binding and permease protein lp_3000 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 28378436 Nonpathogen - transcription regulator lp_1757 2 COG4189 COG4189, Predicted transcriptional regulator Transcription 28377873 Common - DegV family protein lp_1079 53 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 28377963 Common rfbB dTDP-glucose 4,6-dehydratase lp_1189 229 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 28377152 Common - ABC transporter subunit (putative) lp_0219 21 COG4721 COG4721, Predicted membrane protein Function unknown 28379206 Common pucK xanthine / uracil transport protein lp_2710 128 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 28378649 Nonpathogen - transposase, fragment lp_2014 2 None None None 28377240 Common potA spermidine/putrescine ABC transporter, ATP-binding protein lp_0318 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 28378981 Nonpathogen - prophage Lp2 protein 41 lp_2416 3 None None None 28379234 Common - transcription regulator lp_2742 69 COG1725 COG1725, Predicted transcriptional regulators Transcription 28379746 Common - extracellular protein lp_3414 4 None None None 28377073 Common - purine nucleoside phosphorylase (putative) lp_0125 34 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 28377566 Common dnaX DNA-directed DNA polymerase III, gamma/tau subunit lp_0698 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 28379892 Common clpL ATP-dependent Clp protease, ATP-binding subunit ClpL lp_3583 223 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 28377030 Common - integral membrane protein lp_0068 47 COG2966 COG2966, Uncharacterized conserved protein Function unknown 28378832 Common - integral membrane protein lp_2232 167 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 28379688 Common - amino acid transport protein lp_3339 109 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 28377480 Common rpiA1 ribose-5-phosphate isomerase A lp_0602 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 28379098 Common - integral membrane protein lp_2564 9 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 28378467 Common - transcription regulator lp_1795 7 COG1846 MarR, Transcriptional regulators Transcription 28377213 Common - transcription regulator lp_0290 64 COG1316 LytR, Transcriptional regulator Transcription 28377459 Common npsA non-ribosomal peptide synthetase NpsA lp_0578 222 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 28378712 Nonpathogen - hypothetical protein lp_2088 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 28379614 Common - hydrolase, HAD superfamily, Cof family lp_3237 122 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28378773 Nonpathogen - hypothetical protein lp_2160 1 None None None 28379845 Common - sugar transport protein lp_3533 30 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 28378062 Common tagE3 poly(glycerol-phosphate) alpha-glucosyltransferase lp_1312 200 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28378097 Nonpathogen pltA peptide pheromone precursor lp_1354a 1 None None None 28379574 Common bar phosphinothricin N-acetyltransferase lp_3187 86 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 28377823 Common clpC ATP-dependent Clp protease, ATP-binding subunit ClpC lp_1019 224 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 28377401 Common - hypothetical protein lp_0513 20 None None None 28377774 Common - transcription regulator lp_0951 164 COG0583 LysR, Transcriptional regulator Transcription 28377922 Common pcrA ATP-dependent DNA helicase PcrA lp_1144 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 28379952 Common pts38A sorbitol PTS, EIIA lp_3652 23 COG3731 SrlB, Phosphotransferase system sorbitol-specific component IIA Carbohydrate transport and metabolism 28379806 Common - FMN-binding protein lp_3490 8 None None None 28378811 Common - hypothetical protein lp_2212 56 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 28379017 Common - prophage Lp2 protein 3 lp_2454 36 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 28379973 Nonpathogen - cell surface protein precursor lp_3677 1 None None None 28377299 Nonpathogen - hypothetical protein lp_0387 1 None None None 28377616 Common galU UTP--glucose-1-phosphate uridylyltransferase lp_0757 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 28379105 Common bsh4 choloylglycine hydrolase lp_2572 26 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 28378733 Common glnPH2 glutamine ABC transporter, substrate binding and permease protein lp_2111 184 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 28378621 Common msrA4 protein-methionine-S-oxide reductase lp_1979 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 28378690 Common - methyltransferase (putative) lp_2059 81 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 28378294 Common - ribosomal protein (putative) lp_1593 18 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 28377578 Common phnX phosphonoacetaldehyde hydrolase lp_0711 27 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 28378640 Common - transcription regulator (putative) lp_2003 50 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 28377287 Common glpF3 glycerol uptake facilitator protein lp_0372 132 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 28377137 Common - acetyltransferase (putative) lp_0202 28 COG0456 RimI, Acetyltransferases General function prediction only 28379916 Common - sugar transport protein lp_3611 169 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377039 Common - hypothetical protein lp_0077 3 None None None 28379788 Common ram1 alpha-L-rhamnosidase (putative) lp_3471 13 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 28377768 Common - hypothetical protein lp_0945 4 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 28378607 Common glyS glycine--tRNA ligase, beta chain lp_1964 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 28377183 Common pepM methionyl aminopeptidase lp_0257 241 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 28377728 Common - GTPase lp_0896 210 COG2262 HflX, GTPases General function prediction only 28377763 Common pepN membrane alanine aminopeptidase lp_0937 163 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 28377423 Common pth peptidyl-tRNA hydrolase lp_0538 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 28378019 Common gnd1 6-phosphogluconate dehydrogenase-like protein lp_1251 156 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 28378756 Common ftsW cell division protein FtsW lp_2137 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 28379316 Common - extracellular protein lp_2845 8 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 28379489 Common - cell surface protein precursor lp_3072 8 None None None 28379059 Nonpathogen - hypothetical protein lp_2513 1 None None None 28378515 Common mrr mrr restriction system protein lp_1858 41 COG1715 Mrr, Restriction endonuclease Defense mechanisms 28379080 Common - ABC transporter, substrate binding protein lp_2541 55 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 28379431 Common - cell surface protein precursor (putative) lp_3001 17 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 28379906 Common pts36A galactitol PTS, EIIA lp_3599 23 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 28379416 Common livE branched-chain amino acid ABC transporter, ATP-binding protein lp_2981 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 28379169 Common est1 acetylesterase lp_2660 37 COG0627 COG0627, Predicted esterase General function prediction only 28377632 Common argH argininosuccinate lyase lp_0776 237 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 28378802 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase lp_2199 225 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 28378180 Common ftsK1 cell division protein FtsK lp_1461 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 28377177 Common selA L-seryl-tRNA(Sec) selenium transferase (putative) lp_0251 72 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 28379065 Common - transcription regulator, AsnC-type lp_2521 154 COG1522 Lrp, Transcriptional regulators Transcription 28378038 Common - glycosyltransferase lp_1276 101 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28377130 Common nha1 Na(+)/H(+) antiporter lp_0192 50 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 28378876 Common tgt queuine tRNA-ribosyltransferase lp_2282 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 28378023 Common - hypothetical protein lp_1257 4 None None None 28379484 Nonpathogen - extracellular protein, C-terminal fragment lp_3066a 1 None None None 28377671 Common glmS1 D-fructose-6-phosphate amidotransferase lp_0822 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 28379698 Nonpathogen - hypothetical protein lp_3351 1 None None None 28377595 Common - hypothetical protein lp_0734 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 28377892 Common citR citrate lyase regulator lp_1103 64 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 28378269 Common greA2 transcription elongation factor GreA lp_1563 201 COG0782 GreA, Transcription elongation factor Transcription 28379867 Common araT arabinose transport protein lp_3557 133 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28379824 Common - N-acetylmuramic acid-6-phosphate etherase lp_3508 84 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 28378729 Common cps4B exopolysaccharide biosynthesis protein; chain length determinator lp_2107 175 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 28377666 Common - transcription regulator (putative) lp_0816 8 COG1846 MarR, Transcriptional regulators Transcription 28379507 Common - hypothetical protein lp_3094 7 None None None 28378479 Common - amino acid transport protein lp_1811 163 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 28378905 Common tpx thiol peroxidase lp_2323 93 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 28379440 Common - oxidoreductase (putative) lp_3012 113 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28379647 Common - transport protein lp_3281 106 COG0628 PerM, Predicted permease General function prediction only 28378955 Common - esterase (putative) lp_2385 139 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 28377985 Common - transposase lp_1212 143 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 28379336 Nonpathogen - hypothetical protein lp_2870 4 None None None 28379321 Common - short-chain dehydrogenase/oxidoreductase lp_2851 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 28378464 Common - ABC transporter, ATP-binding protein lp_1791 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28377802 Nonpathogen - integral membrane protein lp_0989 1 None None None 28378014 Common hicD2 L-2-hydroxyisocaproate dehydrogenase lp_1245 146 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 28379437 Common pts23B cellobiose PTS, EIIB lp_3009 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 28378761 Common typA GTP-binding protein TypA lp_2146 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 28379386 Common - transcription regulator lp_2937 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 28377857 Common rpsK 30S ribosomal protein S11 lp_1061 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 28378541 Common rluB pseudouridylate synthase lp_1888 205 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 28378972 Common - prophage Lp2 protein 50 lp_2407 4 None None None 28379705 Common - integral membrane protein lp_3360 80 COG1814 COG1814, Uncharacterized membrane protein Function unknown 28378421 Common asnC asparaginyl-tRNA synthetase lp_1740 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 28378086 Common - hypothetical protein lp_1342 8 None None None 28378931 Common rodA2 rod-shape determining protein lp_2354 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 28377884 Common - transcription regulator lp_1092 127 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 28379138 Common - transcription regulator lp_2615 51 COG1725 COG1725, Predicted transcriptional regulators Transcription 28377812 Common - transcription regulator lp_1000 63 COG1316 LytR, Transcriptional regulator Transcription 28378304 Common - hemolysin homolog lp_1603 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 28379087 Common hisC histidinol-phosphate aminotransferase lp_2551 240 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 28377951 Common cps1A polysaccharide biosynthesis protein lp_1177 8 None None None 28378748 Common comEC ComE operon protein 3 lp_2129 121 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 28378743 Common dapA1 dihydrodipicolinate synthase lp_2123 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 28377678 Common - nitro/flavin reductase lp_0829 62 COG0778 NfnB, Nitroreductase Energy production and conversion 28377881 Common - hypothetical protein lp_1088 139 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 28379275 Common - oxidoreductase lp_2792 52 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 28378725 Common cps4F glycosyltransferase lp_2103 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28379276 Nonpathogen - hypothetical protein lp_2793 2 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 28379829 Common bglG4 transcription antiterminator lp_3514 29 COG3711 BglG, Transcriptional antiterminator Transcription 28377485 Common gltX glutamyl-tRNA synthetase lp_0609 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 28379006 Common - prophage Lp2 protein 14 lp_2443 7 COG3422 COG3422, Uncharacterized conserved protein Function unknown 28378771 Common - metallo-beta-lactamase superfamily protein (putative) lp_2158 157 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 28379659 Common xtp2 xanthosine triphosphate pyrophosphatase lp_3295 200 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 28377452 Common - hypothetical protein lp_0570 12 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 28379493 Nonpathogen - extracellular protein (putative) lp_3077 1 None None None 28378445 Common - bacteriocin immunity protein (putative) lp_1768 75 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 28377684 Common - transport protein lp_0840 177 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28379857 Common pts35C galacitol PTS, EIIC lp_3546 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 28377899 Nonpathogen - hypothetical protein lp_1111 1 None None None 28378830 Common - polyribonucleotide nucleotidyltransferase (putative) lp_2231b 230 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 28379447 Nonpathogen - hypothetical protein lp_3019 1 None None None 28378195 Nonpathogen moaD molybdopterin biosynthesis protein, D chain lp_1479 2 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 28378330 Common smc cell division protein Smc lp_1632 183 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 28379764 Common glpF5 glycerol uptake facilitator protein lp_3436 132 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 28377704 Nonpathogen - hypothetical protein lp_0864 4 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 28377195 Common tagF2 teichoic acid biosynthesis protein lp_0269 189 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 28378405 Common - 4-aminobutyrate aminotransferase lp_1721 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 28379683 Nonpathogen ISP2-C transposase, C-terminal fragment lp_3332 1 None None None 28379938 Common sacK2 fructokinase lp_3637 38 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 28378313 Common rpoZ DNA-directed RNA polymerase, omega subunit lp_1613 18 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 28378392 Common - hypothetical protein lp_1703 69 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 28378567 Common mntA cadmium-/manganese-transporting P-type ATPase lp_1919 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 28379378 Common pts21A PTS, EIIA lp_2927 20 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 28377773 Common - transcription regulator lp_0950 18 COG1476 COG1476, Predicted transcriptional regulators Transcription 28378043 Common - alkaline phosphatase superfamily protein lp_1283 48 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 28378407 Common - hydrolase, HAD superfamily, Cof family lp_1723 120 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28378388 Nonpathogen - hypothetical protein lp_1699 2 None None None 28378684 Common pyrH uridylate kinase lp_2053 245 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 28379915 Common iolG3 myo-inositol 2-dehydrogenase lp_3608 160 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 28379877 Common nanA N-acetylneuraminate lyase lp_3568 234 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 28378477 Common - hypothetical protein lp_1807 36 COG4420 COG4420, Predicted membrane protein Function unknown 28377112 Common - transcription regulator lp_0172 126 COG1609 PurR, Transcriptional regulators Transcription 28377261 Common tagG teichoic acid ABC transporter, permease protein lp_0343 115 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 28378502 Common - integral membrane protein lp_1842 170 COG0344 COG0344, Predicted membrane protein Function unknown 28377919 Common xpt xanthine phosphoribosyltransferase lp_1139 39 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 28377042 Common - intracellular protease/amidase (putative) lp_0081 81 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 28377260 Nonpathogen - hypothetical protein lp_0340 1 None None None 28377448 Common nadE NAD synthetase lp_0566 175 COG0171 NadE, NAD synthase Coenzyme metabolism 28378488 Common - transcription repressor lp_1820 41 COG0456 RimI, Acetyltransferases General function prediction only 28379143 Common - transcription regulator lp_2622 9 COG1396 HipB, Predicted transcriptional regulators Transcription 28379522 Common - short-chain dehydrogenase/oxidoreductase lp_3110 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 28379520 Common - transcription regulator (putative) lp_3107 15 COG1309 AcrR, Transcriptional regulator Transcription 28379239 Nonpathogen - hypothetical protein lp_2748 1 None None None 28378979 Nonpathogen - prophage Lp2 protein 43 lp_2414 1 None None None 28377274 Common - hypothetical protein lp_0359 17 COG3410 COG3410, Uncharacterized conserved protein Function unknown 28377637 Common - lipoprotein precursor, peptide binding protein OppA homolog lp_0783 174 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 28377267 Common hicD1 L-2-hydroxyisocaproate dehydrogenase lp_0350 146 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 28377726 Common - transport protein lp_0894 5 COG0730 COG0730, Predicted permeases General function prediction only 28378001 Common - repeat unit transporter lp_1231 52 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 28378821 Common - GTP pyrophosphokinase (putative) lp_2223 116 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 28379082 Common - ABC transporter, ATP-binding protein lp_2543 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 28377534 Common - prophage Lp1 protein 39 lp_0662 7 None None None 28378413 Common idi1 isopentenyl pyrophosphate isomerase lp_1732 81 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 28379079 Nonpathogen - hypothetical protein lp_2540 1 None None None 28379753 Nonpathogen - hypothetical protein lp_3422 1 None None None 28377139 Common serC phosphoserine aminotransferase lp_0204 117 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 28379027 Common - prophage Lp3 protein 14, terminase small subunit lp_2467 17 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 28378964 Nonpathogen - prophage Lp2 protein 58 lp_2399 2 COG5546 COG5546, Small integral membrane protein Function unknown 28377475 Common mleP1 malate transport protein lp_0594 160 COG0679 COG0679, Predicted permeases General function prediction only 28377206 Common hpk2 histidine protein kinase; sensor protein lp_0282 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 28378561 Common pps phosphoenolpyruvate synthase lp_1912 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 28379808 Common apbE3 thiamin biosynthesis lipoprotein ApbE lp_3492 135 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 28376983 Common rpsR 30S ribosomal protein S18 lp_0011 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 28378110 Common gtcA1 teichoic acid glycosylation protein (putative) lp_1372 10 COG2246 COG2246, Predicted membrane protein Function unknown 28377706 Common gmk2 guanylate kinase lp_0866 208 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 28378240 Common - GTPase lp_1528 23 COG1161 COG1161, Predicted GTPases General function prediction only 28379710 Common - hypothetical protein lp_3367 4 None None None 28378123 Common argS arginyl-tRNA synthetase lp_1391 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28378267 Common - hypothetical protein lp_1561 186 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 28378528 Common papL tRNA CCA-pyrophosphorylase lp_1873 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 28378741 Common - hypothetical protein lp_2121 5 None None None 28379677 Nonpathogen - hypothetical protein lp_3322 2 None None None 28378651 Common dltD D-alanyl transfer protein DltD lp_2016 13 COG3966 DltD, Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 28377198 Common - transcription regulator (putative) lp_0273 60 COG1959 COG1959, Predicted transcriptional regulator Transcription 28377223 Nonpathogen - membrane-bound protease, CAAX family lp_0300 5 None None None 28378073 Common - sugar ABC transporter, permease protein (putative) lp_1325 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 28378220 Common - transcription regulator (putative) lp_1506 52 COG3655 COG3655, Predicted transcriptional regulator Transcription 28377646 Nonpathogen - hypothetical protein lp_0793 1 None None None 28379425 Common mntH2 manganese transport protein lp_2992 91 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 28377937 Common cspP cold shock protein CspP lp_1160 181 COG1278 CspC, Cold shock proteins Transcription 28378068 Common rsuA pseudouridylate synthase lp_1319 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 28377125 Common pts1BCA sucrose PTS, EIIBCA lp_0185 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28378926 Common hicD3 L-2-hydroxyisocaproate dehydrogenase lp_2349 155 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 28379782 Common glpF6 glycerol uptake facilitator protein lp_3463 122 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 28377863 Common - hypothetical protein lp_1068 12 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 28378509 Common dprA DNA processing protein lp_1852 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 28379505 Common gabD succinate-semialdehyde dehydrogenase (NAD(P)+) lp_3092 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 28379211 Common ica3 glycosyltransferase (putative) lp_2716 206 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 28377429 Common mesJ cell cycle protein MesJ lp_0545 215 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 28379070 Common - acetyltransferase (putative) lp_2526 21 COG0456 RimI, Acetyltransferases General function prediction only 28378658 Common - transposase, fragment lp_2023 46 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28377557 Common - prophage Lp1 protein 65 lp_0688 7 None None None 28377098 Nonpathogen - hypothetical protein lp_0156 1 None None None 28378613 Common phoH phosphate starvation-inducible protein lp_1970 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 28378499 Common - transcription regulator lp_1838 184 COG0583 LysR, Transcriptional regulator Transcription 28377393 Common sdaC serine transporter lp_0502 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 28379838 Common - hypothetical protein lp_3524 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 28378129 Common - hypothetical protein lp_1397 2 None None None 28377830 Common fusA2 elongation factor G lp_1027 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 28377309 Nonpathogen - hypothetical protein lp_0402 1 None None None 28377807 Nonpathogen - hypothetical protein lp_0995 1 None None None 28377907 Common - amino acid transport protein lp_1120 183 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 28378329 Common rnc ribonuclease III lp_1631 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 28378340 Common - cell surface protein precursor lp_1643 13 None None None 28379908 Common pts36C galactitol PTS, EIIC lp_3601 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 28379869 Common - transcription regulator lp_3559 164 COG1737 RpiR, Transcriptional regulators Transcription 28377850 Common rpmD 50S ribosomal protein L30 lp_1054 39 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 28378178 Common - hypothetical protein lp_1459 6 COG5584 COG5584, Predicted small secreted protein Function unknown 28377800 Nonpathogen - hypothetical protein lp_0984 1 COG0789 SoxR, Predicted transcriptional regulators Transcription 28378122 Common - acetyltransferase (putative) lp_1390 68 COG2153 ElaA, Predicted acyltransferase General function prediction only 28379334 Nonpathogen - hypothetical protein lp_2867 1 None None None 28379660 Common folC2 folylpolyglutamate synthase lp_3296 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 28377501 Nonpathogen - prophage Lp1 protein 4 lp_0627 1 None None None 28377302 Common thgA1 galactoside O-acetyltransferase lp_0393 184 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 28377467 Common pts10A mannose PTS, EIIA lp_0586 93 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 28378878 Common ruvB Holliday junction DNA helicase B lp_2286 218 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 28379343 Common maa2 maltose O-acetyltransferase lp_2878 104 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 28379401 Common - metal-dependent hydrolase (putative) lp_2961 29 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 28379091 Common hisA phosphoribosylformimino-5-aminoimidazole carboxamideribotide isomerase lp_2556 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 28377718 Common bglG1 transcription antiterminator lp_0885 29 COG3711 BglG, Transcriptional antiterminator Transcription 28379606 Common - RNA methyltransferase lp_3226 196 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 28377904 Common mleR1 malolactic regulator lp_1116 160 COG0583 LysR, Transcriptional regulator Transcription 28377365 Common glmU UDP-N-acetylglucosamine pyrophosphorylase lp_0467 234 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 28379645 Common kup2 potassium uptake protein lp_3279 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 28378115 Common sat sulfate adenylyltransferase lp_1378 64 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 28378644 Common - transposase, fragment lp_2007 19 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28379722 Nonpathogen - prophage Lp4 protein 5 lp_3385 1 None None None 28377001 Nonpathogen - hypothetical protein lp_0030 1 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 28379046 Common - ABC transporter, ATP-binding and permease protein lp_2497 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 28377245 Nonpathogen - hypothetical protein lp_0324 1 None None None 28378368 Common accC2 acetyl-CoA carboxylase, biotin carboxylase subunit lp_1678 228 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 28379441 Common - transcription regulator lp_3013 94 COG0789 SoxR, Predicted transcriptional regulators Transcription 28378050 Common - hypothetical protein lp_1293 61 COG0622 COG0622, Predicted phosphoesterase General function prediction only 28379923 Common pts37BC sorbitol PTS, EIIBC lp_3619 22 COG3732 SrlE, Phosphotransferase system sorbitol-specific component IIBC Carbohydrate transport and metabolism 28377354 Common metS methionine--tRNA ligase lp_0454 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28379181 Common - Na(+)/H(+) antiporter lp_2674 118 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 28377043 Common - oxidoreductase lp_0082 181 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 28379179 Common - integral membrane protein lp_2671 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 28378853 Common - transcription regulator lp_2259 122 COG0789 SoxR, Predicted transcriptional regulators Transcription 28379392 Nonpathogen - hypothetical protein lp_2946 1 None None None 28378588 Common rrp6 response regulator lp_1942 206 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 28378318 Common pppL serine/threonine specific protein phosphatase (putative) lp_1618 138 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 28379376 Nonpathogen - cell surface protein precursor lp_2925 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 28379981 Common - cell division protein lp_3687 210 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 28377609 Common pstA phosphate ABC transporter, ATP-binding protein lp_0750 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 28378672 Common rbfA ribosome-binding factor A lp_2039 131 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 28379672 Common pflA2 formate acetyltransferase activating enzyme lp_3314 90 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 28377340 Common - hypothetical protein lp_0438 4 None None None 28377008 Common - hydrolase lp_0041 60 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 28379188 Common araT2 aromatic amino acid specific aminotransferase lp_2684 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 28378571 Common dapE1 succinyl-diaminopimelate desuccinylase lp_1923 211 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 28378910 Common - signaling protein containing GAF domain (putative) lp_2330 80 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 28378171 Common prsA peptidylprolyl isomerase lp_1452 74 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 28377698 Common pepX x-prolyl-dipeptidyl aminopeptidase lp_0857 12 COG2936 COG2936, Predicted acyl esterases General function prediction only 28377084 Common - oxidoreductase lp_0136 178 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 28377256 Common - integral membrane protein lp_0336 50 COG1268 BioY, Uncharacterized conserved protein General function prediction only 28377420 Common - hypothetical protein lp_0535 8 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 28377936 Common - hypothetical protein lp_1159 3 None None None 28376976 Common dnaN DNA-directed DNA polymerase III, beta chain lp_0002 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 28377614 Common lgt prolipoprotein diacylglyceryl transferase lp_0755 191 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 28376993 Common glgC glucose-1-phosphate adenylyltransferase lp_0021 223 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 28379626 Common - 3',5'-cyclic-nucleotide phosphodiesterase lp_3251 91 COG1409 Icc, Predicted phosphohydrolases General function prediction only 28378448 Nonpathogen - integral membrane protein lp_1773 1 None None None 28378917 Common cshA3 recombination factor protein RarA lp_2337 247 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 28378057 Common metK S-adenosylmethionine synthetase lp_1301 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 28377346 Nonpathogen - hypothetical protein lp_0444 1 None None None 28377982 Nonpathogen - hypothetical protein lp_1208 1 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 28378237 Common ica1 glycosyltransferase lp_1524 211 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 28377620 Common - hypothetical protein lp_0762 42 COG2323 COG2323, Predicted membrane protein Function unknown 28377203 Nonpathogen - hypothetical protein lp_0279 2 None None None 28379882 Common - hypothetical protein lp_3573 6 None None None 28378231 Common rplT 50S ribosomal protein L20 lp_1517 186 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 28377370 Common - hydrolase, HAD superfamily, Cof family lp_0475 123 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28377186 Common - hypothetical protein lp_0260 12 COG3877 COG3877, Uncharacterized protein conserved in bacteria Function unknown 28377020 Common - transcription regulator lp_0057 166 COG0583 LysR, Transcriptional regulator Transcription 28379194 Common rexA ATP-dependent nuclease, subunit A lp_2693 227 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 28379798 Common galK galactokinase lp_3482 91 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 28379127 Common tal1 fructose-6-phosphate aldolase lp_2600 103 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 28379775 Common - extracellular protein lp_3452 6 None None None 28377029 Common bsh2 choloylglycine hydrolase lp_0067 53 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 28378739 Common tig trigger factor lp_2118 215 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 28378339 Nonpathogen - hypothetical protein lp_1642 3 None None None 28378637 Nonpathogen - hypothetical protein lp_2000 1 None None None 28378799 Common ftsQ cell division initiation protein FtsQ lp_2195 12 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 28377515 Common - prophage Lp1 protein 19 lp_0642 5 None None None 28379462 Common - oxidoreductase (putative) lp_3034 17 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 28378574 Common mutT 7,8-dihydro-8-oxoguanine-triphosphatase (putative) lp_1927 46 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 28377999 Common - cell surface protein precursor lp_1229 9 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 28377419 Common - integral membrane protein lp_0533 11 COG4708 COG4708, Predicted membrane protein Function unknown 28379744 Common - extracellular protein lp_3412 7 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 28378166 Common - extracellular protein lp_1446 14 COG5665 NOT5, CCR4-NOT transcriptional regulation complex, NOT5 subunit Transcription 28377541 Nonpathogen - prophage Lp1 protein 46 lp_0669 1 None None None 28377064 Common thiE thiamine-phosphate pyrophosphorylase lp_0115 198 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 28378594 Common - transcription regulator lp_1948 35 COG1846 MarR, Transcriptional regulators Transcription 28378988 Common - prophage Lp2 protein 34 lp_2423 17 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 28379158 Common acm2 muramidase lp_2645 68 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 28378609 Common recO DNA repair protein RecO lp_1966 37 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 28377410 Common - hypothetical protein lp_0524 56 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 28377105 Common - integral membrane protein lp_0164 4 None None None 28377787 Nonpathogen - hypothetical protein lp_0967 1 None None None 28378947 Common glyA glycine hydroxymethyltransferase lp_2375 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 28377385 Common - hypothetical protein lp_0493 97 COG0439 AccC, Biotin carboxylase Lipid metabolism 28378958 Nonpathogen - hypothetical protein lp_2391 2 None None None 28378361 Common fabH2 3-oxoacyl-(acyl carrier protein) synthase III lp_1671 203 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 28377956 Nonpathogen cps1F exopolysaccharide biosynthesis protein lp_1182 1 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 28377716 Common glnP glutamine ABC transporter, permease protein lp_0883 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 28377236 Nonpathogen - integral membrane protein lp_0314 1 None None None 28377550 Nonpathogen - prophage Lp1 protein 55 lp_0678 1 None None None 28379726 Common - prophage Lp4 protein 1, integrase lp_3390 126 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 28378699 Common - glycosyltransferase lp_2071 173 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 28379801 Common melA alpha-galactosidase lp_3485 43 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 28378692 Common - hypothetical protein lp_2061 15 COG3763 COG3763, Uncharacterized protein conserved in bacteria Function unknown 28378991 Common - prophage Lp2 protein 31 lp_2426 3 None None None 28377416 Common argB acetylglutamate kinase lp_0530 213 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 28377460 Common panD aspartate alpha-decarboxylase lp_0579 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 28378208 Common moaC molybdenum cofactor biosynthesis protein C lp_1492 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 28378381 Nonpathogen - transcription regulator, N-terminal fragment (putative) lp_1693 2 COG1309 AcrR, Transcriptional regulator Transcription 28378933 Common hlyA alpha-hemolysin homolog lp_2358 186 COG0759 COG0759, Uncharacterized conserved protein Function unknown 28377220 Common - extracellular protein lp_0297 3 None None None 28379500 Common asnB2 asparagine synthase (glutamine-hydrolysing) lp_3085 161 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 28378813 Common rrmA rRNA large subunit methyltransferase A lp_2215 63 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 28379103 Common - hypothetical protein lp_2569 5 None None None 28379569 Common - hypothetical protein lp_3179 3 None None None 28377924 Common - lipoprotein precursor lp_1146 9 COG4851 CamS, Protein involved in sex pheromone biosynthesis General function prediction only 28379638 Common purB adenylosuccinate lyase lp_3269 241 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 28379302 Common - reductase (putative) lp_2826 76 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 28379572 Common - integral membrane protein lp_3184 16 COG4392 COG4392, Predicted membrane protein Function unknown 28379419 Common livB branched-chain amino acid ABC transporter, permease protein lp_2984 175 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 28379248 Common - hypothetical protein lp_2760 57 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 28379371 Common - amino acid transport protein lp_2920 184 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 28377571 Common - hypothetical protein lp_0704 20 COG3870 COG3870, Uncharacterized protein conserved in bacteria Function unknown 28377075 Common - oxidoreductase (putative) lp_0127 73 COG0431 COG0431, Predicted flavoprotein General function prediction only 28377157 Common - transcription regulator lp_0225 43 COG1476 COG1476, Predicted transcriptional regulators Transcription 28378848 Common - hypothetical protein lp_2253 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 28378471 Nonpathogen - hypothetical protein lp_1799 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 28377829 Common rpsG 30S ribosomal protein S7 lp_1026 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 28377911 Common cydB cytochrome D ubiquinol oxidase, subunit II lp_1126 152 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 28378302 Common xseB exodeoxyribonuclease VII, small subunit lp_1601 80 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 28377379 Nonpathogen - hypothetical protein lp_0485 1 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 28377734 Common napA2 Na(+)/H(+) antiporter lp_0902 67 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 28377037 Common - acyl carrier protein phosphodiesterase (putative) lp_0075 89 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 28378807 Common - integral membrane protein lp_2205 3 None None None 28379860 Common - transcription regulator lp_3549 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 28379560 Common pmg9 phosphoglyceromutase lp_3170 157 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 28379348 Nonpathogen - integral membrane protein lp_2885 1 None None None 28377450 Common - hypothetical protein lp_0568 5 None None None 28378714 Common - metal-dependent hydrolase of the beta-lactamase superfamily III (putative) lp_2090 126 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 28378628 Common relA GTP pyrophosphokinase lp_1987 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 28378674 Common - ribosomal protein HS6-type (S12/L30/L7a) lp_2041 17 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 28378182 Common ISP1 transposase lp_1463 49 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28377247 Common - ABC transporter, ATP-binding protein lp_0326 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28379445 Nonpathogen - hypothetical protein lp_3017 3 COG4043 COG4043, Uncharacterized conserved protein Function unknown 28379048 Common - ABC transporter, ATP-binding and permease protein lp_2499 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 28377992 Nonpathogen cps3E polysaccharide biosynthesis protein (putative) lp_1221 1 None None None 28377285 Common glpK glycerol kinase lp_0370 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 28378292 Common - transcription regulator lp_1591 21 COG1309 AcrR, Transcriptional regulator Transcription 28378280 Common - hypothetical protein lp_1576 96 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 28379015 Nonpathogen - prophage Lp2 protein 5 lp_2452 1 None None None 28379600 Common agl4 alpha-glucosidase lp_3220 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 28378837 Common - phosphoesterase (putative) lp_2238 21 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 28377307 Common brnQ1 branched-chain amino acid transport protein lp_0399 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 28379131 Common - oxidoreductase lp_2604 166 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 28379930 Common agl6 alpha-glucosidase lp_3627 167 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 28378142 Common pbp2A penicillin binding protein 2A lp_1413 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 28378735 Common - hypothetical protein lp_2113 3 None None None 28377954 Common cps1D glycosyltransferase lp_1180 14 None None None 28377495 Common rplK 50S ribosomal protein L11 lp_0619 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 28378454 Common lspA signal peptidase II lp_1780 198 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 28377756 Nonpathogen - hypothetical protein lp_0928 1 None None None 28379748 Common - transcription regulator (putative) lp_3416 10 COG1846 MarR, Transcriptional regulators Transcription 28379020 Nonpathogen - prophage Lp3 protein 24 lp_2457 1 None None None 28378155 Common - glycosyltransferase lp_1430 174 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 28377225 Common - extracellular protein lp_0302 13 COG3889 COG3889, Predicted solute binding protein General function prediction only 28379388 Nonpathogen - cell surface protein precursor lp_2940 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 28377170 Common - hypothetical protein lp_0243 25 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 28377564 Common rsmc 16S RNA methylase lp_0695 99 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 28377161 Common mtlR transcription regulator, mannitol operon lp_0231 28 COG3711 BglG, Transcriptional antiterminator Transcription 28377181 Common metC1 cystathionine beta-lyase lp_0255 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 28378665 Common truB pseudouridylate synthase lp_2032 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 28379724 Common - prophage Lp4 protein 3, phage-like repressor lp_3388 8 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 28379818 Common - transcription regulator lp_3502 182 COG0583 LysR, Transcriptional regulator Transcription 28378564 Nonpathogen - lipoprotein precursor lp_1915 1 None None None 28379208 Common - hypothetical protein lp_2713 22 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28379544 Common ulaA ascorbate-specific PTS system enzyme IIC lp_3136 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 28377314 Common plnM immunity protein PlnM lp_0409 2 None None None 28378287 Nonpathogen - hypothetical protein lp_1584 4 None None None 28379811 Common - transcription regulator lp_3495 191 COG0583 LysR, Transcriptional regulator Transcription 28378133 Common pbg3 6-phospho-beta-glucosidase lp_1401 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 28379421 Nonpathogen - hypothetical protein lp_2987 3 None None None 28377947 Common - UDP-N-acetylglucosamine 2-epimerase lp_1173 156 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 28379173 Common - hypothetical protein lp_2664 59 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 28378260 Common - integral membrane protein lp_1553 208 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 28377871 Common rplM 50S ribosomal protein L13 lp_1077 220 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 28379733 Common pacL3 cation transporting P-type ATPase lp_3398 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 28377054 Common - cobalt transport protein lp_0101 14 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 28377107 Common dak1A glycerone kinase lp_0166 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 28378939 Common atpG F0F1 ATP synthase subunit gamma lp_2365 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 28377721 Common - amino acid transport protein lp_0888 170 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 28378316 Common fmt methionyl-tRNA formyltransferase lp_1616 222 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 28378746 Common rpsT 30S ribosomal protein S20 lp_2126 119 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 28378364 Common fabG1 3-oxoacyl-[acyl-carrier protein] reductase lp_1674 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 28377878 Common aroA 3-deoxy-7-phosphoheptulonate synthase lp_1085 183 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 28377642 Common gapB glyceraldehyde 3-phosphate dehydrogenase lp_0789 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 28378434 Common - methylase (putative) lp_1754 20 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 28379294 Common - transport protein lp_2816 47 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 28378886 Common - hypothetical protein lp_2300 88 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 28379289 Nonpathogen - hypothetical protein lp_2809 1 None None None 28378394 Nonpathogen - hypothetical protein lp_1705 1 None None None 28377136 Common - lipoprotein precursor, peptide binding protein OppA homolog lp_0201 186 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 28377150 Common - ABC transporter, permease protein lp_0217 14 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 28378791 Common dapF diaminopimelate epimerase lp_2185 201 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 28378983 Common - prophage Lp2 protein 39 lp_2418 5 None None None 28379586 Common gidB glucose-inhibited division protein B lp_3201 178 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 28377369 Nonpathogen - lipoprotein precursor (putative) lp_0473 1 None None None 28377886 Common mtsC manganese ABC transporter, ATP-binding protein lp_1095 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 28378921 Common - hypothetical protein lp_2342 6 COG1476 COG1476, Predicted transcriptional regulators Transcription 28377435 Common dtpT di-/tripeptide transport protein lp_0551 81 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 28378256 Common - prenyltransferase lp_1546 18 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 28379241 Common - aminotransferase lp_2751 219 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 28378503 Common - hypothetical protein lp_1843 42 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 28378474 Common - transport protein lp_1803 60 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28379224 Common - oxidoreductase (putative) lp_2732 124 COG0431 COG0431, Predicted flavoprotein General function prediction only 28379954 Common pts38C sorbitol PTS, EIIC lp_3654 22 COG3730 SrlA, Phosphotransferase system sorbitol-specific component IIC Carbohydrate transport and metabolism 28377360 Common ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase lp_0460 177 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 28378091 Nonpathogen - hypothetical protein lp_1348 4 None None None 28379160 Common pts19D N-acetylgalactosamine-specific PTS system transporter subunit IID lp_2648 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 28379703 Common - transport protein lp_3358 145 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 28378189 Common - ABC transporter component, iron regulated (putative) lp_1472 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 28379516 Common fhuD ferrichrome ABC transporter, substrate binding lipo protein lp_3103 58 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 28378855 Common - hypothetical protein lp_2261 11 COG4768 COG4768, Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain General function prediction only 28378755 Common pycA pyruvate carboxylase lp_2136 240 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 28377462 Common npsB non-ribosomal peptide synthetase NpsB lp_0581 186 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 28377776 Common - transcription regulator lp_0954 15 COG1846 MarR, Transcriptional regulators Transcription 28377380 Common - hypothetical protein lp_0486 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 28378439 Common - hypothetical protein lp_1762 5 None None None 28379789 Common - sugar transport protein lp_3472 135 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28379453 Nonpathogen - hypothetical protein lp_3025 1 None None None 28379273 Common - transport protein lp_2789 53 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 28378569 Common - transport protein lp_1921 191 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377540 Nonpathogen - prophage Lp1 protein 45 lp_0668 1 None None None 28378106 Common uvrA2 excinuclease ABC, subunit A lp_1364 244 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 28377547 Common - prophage Lp1 protein 52, endolysin lp_0675 27 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 28377799 Common - amino acid transport protein lp_0982 111 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 28377792 Nonpathogen - hypothetical protein lp_0972 2 None None None 28378160 Common ribH riboflavin synthase, beta chain lp_1438 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 28377477 Common pgm2 phosphoglycerate mutase lp_0597 157 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 28379552 Common - oxidoreductase (putative) lp_3158 28 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 28377810 Common - integral membrane protein lp_0998 47 COG2966 COG2966, Uncharacterized conserved protein Function unknown 28379394 Nonpathogen - integral membrane protein lp_2949 1 COG4640 COG4640, Predicted membrane protein Function unknown 28379960 Common rbsK3 ribokinase lp_3660 213 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 28377143 Common - hypothetical protein lp_0208 15 COG5646 COG5646, Uncharacterized conserved protein Function unknown 28379657 Common tag3 DNA-3-methyladenine glycosylase I lp_3293 130 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 28379685 Common adeC adenine deaminase lp_3334 69 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 28379854 Common - multidomain protein lp_3543 40 COG3711 BglG, Transcriptional antiterminator Transcription 28378197 Common narK nitrite extrusion protein lp_1481 121 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 28377974 Common galE2 UDP-glucose 4-epimerase lp_1200 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28379936 Common - alpha-1,2-mannosidase (putative) lp_3634 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 28377024 Common - acetoacetate decarboxylase (putative) lp_0061 4 COG4689 Adc, Acetoacetate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 28378928 Common - amino acid ABC transporter, permease protein lp_2351 119 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 28379899 Common rhaD rhamnulose-1-phosphate aldolase lp_3592 41 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 28379089 Common hisI phosphoribosyl-AMP cyclohydrolase lp_2553 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 28379679 Common - glycine betaine/carnitine/choline transport protein lp_3324 95 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 28378169 Common - extracellular protein lp_1449 5 None None None 28379198 Common pyrF orotidine-5'-phosphate decarboxylase lp_2698 154 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 28378409 Nonpathogen - hypothetical protein lp_1726 3 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 28379004 Common - prophage Lp2 protein 17 lp_2440 4 COG1100 COG1100, GTPase SAR1 and related small G proteins General function prediction only 28377771 Common - hypothetical protein lp_0948 12 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 28379681 Common - hypothetical protein lp_3330 12 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 28378349 Common trpA tryptophan synthase subunit beta lp_1657 226 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 28379859 Common pts35A galacitol PTS, EIIA lp_3548 26 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 28379982 Common rnpA ribonuclease P lp_3688 40 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 28377897 Common citF citrate lyase, alpha chain lp_1109 28 COG3051 CitF, Citrate lyase, alpha subunit Energy production and conversion 28379584 Common parA chromosome partitioning protein, membrane-associated ATPase lp_3199 218 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 28378605 Common rpoD RNA polymerase sigma factor RpoD lp_1962 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 28378777 Common recD exodeoxyribonuclease V, alpha chain lp_2168 143 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 28377987 Common - hypothetical protein lp_1214 3 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 28378703 Common - nitrate ABC transporter, permease protein lp_2077 84 COG4986 COG4986, ABC-type anion transport system, duplicated permease component Inorganic ion transport and metabolism 28377759 Common hpaG 2-hydroxyhepta-2,4-diene-1,7-dioateisomerase / 5-carboxymethyl-2-oxo-hex-3-ene-1,7-dioatedecarboxylase (putative) lp_0931 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 28379042 Common - hypothetical protein lp_2485 62 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 28379309 Common - multidrug transport protein lp_2836 208 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28379696 Common mutY A/G-specific adenine glycosylase (putative) lp_3349 211 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 28379167 Common - glycosyltransferase (putative) lp_2658 191 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28378462 Common - hypothetical protein lp_1789 8 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 28379595 Nonpathogen - hypothetical protein lp_3215 1 None None None 28378600 Nonpathogen - ABC transporter, permease protein lp_1957 1 None None None 28379474 Common dhaT 1,3-propanediol dehydrogenase lp_3051 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 28378272 Common - hypothetical protein lp_1566 6 COG4841 COG4841, Uncharacterized protein conserved in bacteria Function unknown 28377664 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase lp_0814 207 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 28379364 Common - ABC transporter, ATP-binding protein lp_2912 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 28377765 Common hsdM site-specific DNA-methyltransferase (adenine-specific), HsdM subunit lp_0939 162 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 28379253 Common - hypothetical protein lp_2765 6 None None None 28377630 Common luxS S-ribosylhomocysteinase lp_0774 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 28377741 Common ISP2 transposase lp_0911 25 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 28378174 Common ecsA ABC transporter, ATP-binding protein lp_1455 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28377036 Common - hypothetical protein lp_0074 16 COG2378 COG2378, Predicted transcriptional regulator Transcription 28378432 Common recU Holliday junction-specific endonuclease lp_1752 17 COG3331 PrfA, Penicillin-binding protein-related factor A, putative recombinase General function prediction only 28379113 Nonpathogen - hypothetical protein lp_2584 1 None None None 28379318 Common ogt methylated-DNA--[protein]-cysteine S-methyltransferase lp_2848 215 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 28378517 Common - oxidoreductase lp_1860 80 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 28378242 Common nadD nicotinate-nucleotide adenylyltransferase lp_1530 189 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 28379487 Common - hypothetical protein lp_3070 3 None None None 28378873 Common - exopolyphosphatase-related protein (putative) lp_2279 69 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 28379351 Common - hypothetical protein lp_2889 7 None None None 28379482 Nonpathogen - cell surface protein precursor lp_3065 1 None None None 28378751 Common lon endopeptidase La (putative) lp_2132 52 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 28377127 Common sacR sucrose operon repressor lp_0188 129 COG1609 PurR, Transcriptional regulators Transcription 28379418 Common livC branched-chain amino acid ABC transporter, permease protein lp_2983 140 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 28379611 Nonpathogen - hypothetical protein lp_3233 4 None None None 28379533 Common - transcription regulator lp_3124 181 COG0583 LysR, Transcriptional regulator Transcription 28379358 Common - transcription regulator lp_2902 10 COG1309 AcrR, Transcriptional regulator Transcription 28379420 Common livA branched-chain amino acid ABC transporter, substrate binding protein lp_2985 148 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 28379663 Common folB dihydroneopterin aldolase lp_3299 102 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 28377748 Common - membrane-bound protease, CAAX family lp_0919 10 None None None 28377006 Common - hypothetical protein lp_0038 7 COG4863 COG4863, Uncharacterized protein conserved in bacteria Function unknown 28379369 Common ropB transcription regulator lp_2918 4 COG1396 HipB, Predicted transcriptional regulators Transcription 28379758 Common - hypothetical protein lp_3429 3 COG1309 AcrR, Transcriptional regulator Transcription 28378618 Common nfo endonuclease IV lp_1976 100 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 28378903 Common folC1 folylpolyglutamate synthase lp_2321 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 28379323 Common - hypothetical protein lp_2853 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 28377119 Common amy2 alpha-amylase lp_0179 169 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 28377049 Common - extracellular protein, peptide binding protein OppA homolog lp_0092 150 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 28377563 Common nrdH glutaredoxin-like protein NrdH lp_0694 37 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 28379063 Common - cell surface hydrolase (putative) lp_2519 10 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 28378400 Common lysA diaminopimelate decarboxylase lp_1713 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 28379232 Common - ABC transporter, permease protein lp_2740 18 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 28379427 Nonpathogen - hypothetical protein lp_2994 1 None None None 28377743 Common coaA pantothenate kinase lp_0913 80 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 28378970 Nonpathogen - prophage Lp2 protein 52 lp_2405 2 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 28378998 Nonpathogen - prophage Lp2 protein 24 lp_2433 4 None None None 28379624 Common - bacteriocin immunity protein lp_3248 2 None None None 28377939 Common rhe2 ATP-dependent RNA helicase lp_1162 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 28379911 Common - sugar transport protein lp_3604 137 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28378510 Common rnhB ribonuclease HII lp_1853 223 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 28377868 Common - ABC transporter, ATP-binding protein lp_1074 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 28379784 Common brnQ3 branched-chain amino acid transport protein lp_3466 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 28378797 Common ftsZ cell division protein FtsZ lp_2193 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 28378328 Common acpA1 acyl carrier protein lp_1629 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 28378497 Common msrA3 methionine sulfoxide reductase B lp_1836 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 28378125 Common - ABC transporter, ATP-binding and permease protein lp_1393 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 28378055 Common tagE1 poly(glycerol-phosphate) alpha-glucosyltransferase lp_1299 180 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28378494 Nonpathogen - hypothetical protein lp_1833 1 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 28379218 Common purL phosphoribosylformylglycinamidine synthase II lp_2724 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 28378481 Nonpathogen - hypothetical protein lp_1813 1 None None None 28379072 Nonpathogen - hypothetical protein lp_2529 1 None None None 28378551 Nonpathogen - integral membrane protein lp_1900 2 None None None 28378656 Common pbpX2 serine-type D-Ala-D-Ala carboxypeptidase lp_2021 99 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 28379836 Common pts32BC sucrose PTS, EIIBC lp_3522 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28377905 Common mleS malolactic enzyme lp_1118 200 COG0281 SfcA, Malic enzyme Energy production and conversion 28378634 Nonpathogen - hypothetical protein lp_1994 1 None None None 28379946 Common - hypothetical protein lp_3645 21 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 28377647 Common eriC chloride channel protein lp_0794 149 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 28378226 Common dnaB replication initiation and membrane attachment protein DnaB lp_1512 11 COG3611 DnaB, Replication initiation/membrane attachment protein DNA replication, recombination, and repair 28377387 Nonpathogen - hypothetical protein lp_0496 1 None None None 28379863 Common maa3 maltose O-acetyltransferase lp_3553 160 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 28377300 Common - hypothetical protein lp_0388 2 None None None 28377091 Common - ABC transporter, permease protein lp_0148 54 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 28379491 Nonpathogen - cell surface protein precursor lp_3074 1 None None None 28377586 Common gcp O-sialoglycoprotein endopeptidase lp_0721 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 28377806 Nonpathogen - hypothetical protein lp_0994 1 None None None 28377714 Common glnH1 glutamine ABC transporter, substrate binding protein lp_0881 179 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 28377469 Common fabH1 3-oxoacyl-(acyl carrier protein) synthase III lp_0588 215 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 28378017 Common gntP gluconate transport protein lp_1249 76 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 28379096 Common hisX histidine--tRNA ligase (putative) lp_2561 206 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 28377427 Common - hypothetical protein lp_0542 5 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 28379341 Nonpathogen - hypothetical protein lp_2876 1 None None None 28379890 Nonpathogen agrD accesory gene regulator protein D, peptide pheromone precursor lp_3581a 1 None None None 28377902 Common citX apo-citrate lyase phosphoribosyl-ft dephospho-CoA transferase lp_1114 24 COG3697 CitX, Phosphoribosyl-dephospho-CoA transferase (holo-ACP synthetase) Coenzyme metabolism / Lipid metabolism 28378896 Common glnP2 glutamine ABC transporter, permease protein lp_2314 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 28379265 Common pts20A cellobiose PTS, EIIA lp_2780 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 28377943 Nonpathogen - hypothetical protein lp_1166 1 None None None 28379665 Common - ABC transporter substrate binding protein lp_3302 142 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 28377279 Common - short chain dehydrogenase lp_0364 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 28377686 Common ppk polyphosphate kinase lp_0842 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 28377339 Common pts7C cellobiose PTS, EIIC lp_0436 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 28378893 Common thrA2 aspartate kinase lp_2308 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 28379403 Nonpathogen - transcription regulator (putative) lp_2964 1 COG1733 COG1733, Predicted transcriptional regulators Transcription 28378682 Common uppS di-trans-poly-cis-decaprenylcistransferase lp_2051 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 28377993 Nonpathogen cps3F polysaccharide polymerase lp_1222 1 None None None 28378371 Common fabI enoyl-(acyl carrier protein) reductase lp_1681 226 COG0623 FabI, Enoyl- acyl-carrier-protein 28377241 Common - transcription regulator lp_0319 106 COG1396 HipB, Predicted transcriptional regulators Transcription 28379655 Nonpathogen - hypothetical protein lp_3291 1 None None None 28378694 Common lexA LexA repressor lp_2063 167 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 28377040 Common - transport protein lp_0078 42 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 28378003 Nonpathogen - hypothetical protein lp_1234 1 None None None 28378069 Common - hypothetical protein lp_1320 185 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 28378247 Common - hypothetical protein lp_1535 15 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 28379433 Common - hypothetical protein lp_3003 51 COG0622 COG0622, Predicted phosphoesterase General function prediction only 28379717 Nonpathogen - prophage Lp4 protein 10 lp_3380 1 None None None 28377635 Common - hypothetical protein lp_0780 94 COG0391 COG0391, Uncharacterized conserved protein Function unknown 28378945 Common pyrP uracil transport protein lp_2371 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 28379149 Common - lipase/esterase (putative) lp_2631 17 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 28377086 Common - hypothetical protein lp_0138 13 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 28379879 Common - transposase (putative) lp_3570 77 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 28377443 Common proC pyrroline-5-carboxylate reductase lp_0561 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 28379548 Nonpathogen - hypothetical protein lp_3141 1 None None None 28379550 Common - malate dehydrogenase (putative) lp_3150 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 28378949 Common hemK protoporphyrinogen oxidase (putative) lp_2377 228 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 28378663 Common aldB alpha-acetolactate decarboxylase lp_2030 40 COG3527 AlsD, Alpha-acetolactate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 28377978 Common cps2H polysaccharide polymerase lp_1204 7 None None None 28377834 Common rplW 50S ribosomal protein L23 lp_1035 73 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 28378152 Nonpathogen - hypothetical protein lp_1426 1 None None None 28379563 Common - hypothetical protein lp_3173 3 None None None 28379255 Common - acetyltransferase (putative) lp_2767 24 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 28379847 Common bsh1 choloylglycine hydrolase lp_3536 32 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 28377280 Common - integral membrane protein lp_0365 4 None None None 28379712 Common - purine-cytosine transport protein lp_3374 81 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 28378689 Common - endonuclease containing a URI domain (putative) lp_2058 73 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 28376981 Common rpsF 30S ribosomal protein S6 lp_0009 174 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 28377292 Nonpathogen - integral membrane protein lp_0377 1 None None None 28378301 Common xseA exodeoxyribonuclease VII large subunit lp_1600 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 28378635 Nonpathogen - hypothetical protein lp_1995 2 None None None 28379451 Common umuC UV-damage repair protein lp_3023 126 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 28377324 Nonpathogen plnF bacteriocin precursor peptide PlnF (putative) lp_0421 1 None None None 28377110 Common - hypothetical protein lp_0170 37 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 28378012 Common - transcription regulator lp_1243 6 COG1396 HipB, Predicted transcriptional regulators Transcription 28379816 Common - short-chain dehydrogenase/oxidoreductase lp_3500 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 28377593 Common tagO undecaprenyl-phosphate N-acetyl-glucosaminyl transferase lp_0730 229 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 28379730 Common - hypothetical protein lp_3394 6 None None None 28378347 Common trpC indole-3-glycerol-phosphate synthase lp_1655 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 28377272 Common - integral membrane protein lp_0357 33 COG3759 COG3759, Predicted membrane protein Function unknown 28379529 Common - transcription regulator lp_3119 40 COG1309 AcrR, Transcriptional regulator Transcription 28378535 Common rpsA 30S ribosomal protein S1 lp_1882 227 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 28378441 Common - bacteriocin immunity protein (putative) lp_1764 55 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 28379884 Common - integral membrane protein lp_3575 11 None None None 28378144 Common - phosphoesterase lp_1416 72 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 28377532 Common - prophage Lp1 protein 37 lp_0660 11 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 28379140 Common ISP1 transposase lp_2617 49 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28378591 Common - ABC transporter, ATP-binding protein lp_1945 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28377372 Common - hypothetical protein lp_0477 19 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 28377163 Common mtlD mannitol-1-phosphate 5-dehydrogenase lp_0233 87 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 28379366 Common - integral membrane protein lp_2914 15 COG4907 COG4907, Predicted membrane protein Function unknown 28377523 Nonpathogen - prophage Lp1 protein 27 lp_0650 1 None None None 28378583 Common - oxidoreductase (putative) lp_1936 25 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 28377019 Common - cation transport protein lp_0056 103 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 28377022 Common arsC arsenate reductase lp_0059 144 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 28377861 Common hepB1 trans-hexaprenyltranstransferase, component II lp_1066 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 28379192 Common - hypothetical protein lp_2690 82 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28378216 Common narI nitrate reductase, gamma chain lp_1500 59 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 28379728 Common - transport protein lp_3392 156 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377391 Common rbsK1 ribokinase lp_0500 194 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 28379152 Nonpathogen - integral membrane protein lp_2635 1 None None None 28378039 Common - integral membrane protein lp_1277 22 COG0392 COG0392, Predicted integral membrane protein Function unknown 28379751 Common gadB glutamate decarboxylase lp_3420 65 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 28379037 Common - prophage Lp3 protein 2 lp_2479 18 COG1476 COG1476, Predicted transcriptional regulators Transcription 28378611 Common dgk diacylglycerol kinase lp_1968 36 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 28379151 Common metB O-succinylhomoserine (thiol)-lyase lp_2634 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 28377848 Common rplR ribosomal protein L18 lp_1052 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 28378415 Common mvaD diphosphomevalonate decarboxylase lp_1734 32 COG3407 MVD1, Mevalonate pyrophosphate decarboxylase Lipid metabolism 28379870 Common - hypothetical protein lp_3560 8 COG5506 COG5506, Uncharacterized conserved protein Function unknown 28379945 Common - sugar ABC transporter, permease protein lp_3644 141 COG4209 LplB, ABC-type polysaccharide transport system, permease component Carbohydrate transport and metabolism 28377457 Common pts9C mannose PTS, EIIC lp_0576 34 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 28377583 Common gpp glycoprotein endopeptidase lp_0717 201 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 28379468 Common amd aminoacylase lp_3044 167 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 28378385 Common cfa1 cyclopropane-fatty-acyl-phospholipid synthase lp_1696 127 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 28379765 Common trxA3 thioredoxin lp_3437 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 28377855 Common rpmJ 50S ribosomal protein L36 lp_1059a 139 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 28377785 Common - transcription regulator lp_0965 16 COG0640 ArsR, Predicted transcriptional regulators Transcription 28377845 Common rpsN ribosomal protein S14 lp_1048 189 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 28377513 Nonpathogen - prophage Lp1 protein 17 lp_0640 1 None None None 28377813 Common - phosphatase (putative) lp_1001 53 None None None 28377676 Nonpathogen - hypothetical protein lp_0827 4 None None None 28377265 Common - transport protein lp_0348 177 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28378962 Common - hypothetical protein lp_2396 5 COG5294 COG5294, Uncharacterized protein conserved in bacteria Function unknown 28379588 Common - hypothetical protein lp_3205 8 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 28378386 Common - extracellular protein lp_1697 26 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 28378993 Nonpathogen - prophage Lp2 protein 29 lp_2428 1 None None None 28379604 Common - transport protein lp_3224 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 28379913 Common iolG2 myo-inositol 2-dehydrogenase lp_3606 179 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 28378969 Common - prophage Lp2 protein 53 lp_2404 33 None None None 28378710 Common apt adenine phosphoribosyltransferase lp_2086 184 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 28379631 Common - zinc-dependent proteinase (putative) lp_3259 39 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 28377362 Common - zinc/iron ABC transporter, ATP-binding protein lp_0463 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 28379024 Common - prophage Lp3 protein 18 lp_2463 22 COG3740 COG3740, Phage head maturation protease General function prediction only 28378311 Nonpathogen - hypothetical protein lp_1611 1 None None None 28378525 Common thyA thymidylate synthase lp_1870 147 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 28379795 Common galR1 galactose operon repressor lp_3479 122 COG1609 PurR, Transcriptional regulators Transcription 28378596 Common - hypothetical protein lp_1953 3 None None None 28379979 Common - hypothetical protein lp_3684 88 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 28378206 Nonpathogen - hypothetical protein lp_1490 1 None None None 28379643 Nonpathogen - hypothetical protein lp_3275 1 None None None 28379920 Common rihA ribonucleoside hydrolase 1 lp_3615 87 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 28377344 Common - transcription regulator lp_0442 72 COG1737 RpiR, Transcriptional regulators Transcription 28377606 Common pstD phosphate ABC transporter, permease protein lp_0747 228 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 28377945 Common gdh glutamate dehydrogenase lp_1169 168 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 28378868 Common - Holliday junction resolvase-like protein lp_2274 178 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 28377607 Common pstC phosphate ABC transporter, permease protein lp_0748 226 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 28378953 Common cobQ cobyric acid synthase (putative) lp_2382 54 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 28379061 Common - hypothetical protein lp_2515 55 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 28377832 Common rplC 50S ribosomal protein L3 lp_1033 240 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 28377330 Common plnU integral membrane protein PlnU, membrane-bound protease CAAX family lp_0426 16 None None None 28378912 Common - hypothetical protein lp_2332 8 COG4493 COG4493, Uncharacterized protein conserved in bacteria Function unknown 28377622 Common pgm phosphoglucomutase lp_0764 230 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 28377356 Common - DNAse (putative) lp_0456 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 28379475 Common - aryl-alcohol dehydrogenase lp_3054 208 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 28378032 Common - transcription regulator (putative) lp_1267 15 COG1846 MarR, Transcriptional regulators Transcription 28377012 Common aldH aldehyde dehydrogenase lp_0047 218 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 28378138 Common - amino acid efflux protein lp_1409 57 COG1279 COG1279, Lysine efflux permease General function prediction only 28379029 Nonpathogen - prophage Lp3 protein 11 lp_2470 3 None None None 28377794 Common xylP2 sugar transport protein lp_0975 78 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 28379282 Common - amino acid transport protein lp_2799 70 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 28376991 Nonpathogen - hypothetical protein lp_0019 1 None None None 28377617 Common - protein containing diguanylate cyclase/phosphodiesterase domain 2 (EAL) lp_0758 106 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 28377984 Nonpathogen - hypothetical protein lp_1211 1 None None None 28377398 Common murA1 UDP-N-acetylglucosamine 1-carboxyvinyltransferase lp_0510 213 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 28377961 Nonpathogen - hypothetical protein lp_1187 5 None None None 28377316 Common plnO plantaricin biosynthesis protein PlnO lp_0411 53 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 28377508 Common - prophage Lp1 protein 11 lp_0634 2 COG1396 HipB, Predicted transcriptional regulators Transcription 28377658 Common eutD phosphotransacetylase lp_0807 166 COG0280 Pta, Phosphotransacetylase Energy production and conversion 28378353 Common - acetyltransferase (putative) lp_1662 6 None None None 28378642 Common - transposase, fragment lp_2005 8 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28378919 Common - hypothetical protein lp_2340 115 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 28377201 Nonpathogen - hypothetical protein lp_0276 1 None None None 28379690 Common - low temperature requirement C protein (putative) lp_3342 13 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 28378173 Common - cell-cycle regulation histidine triad protein lp_1454 199 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 28376998 Common - hydrolase, HAD superfamily, Cof family lp_0026 94 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28378175 Common ecsB ABC transporter, permease protein lp_1456 12 COG4473 EcsB, Predicted ABC-type exoprotein transport system, permease component Intracellular trafficking and secretion 28378900 Common mreC cell shape determining protein MreC lp_2318 156 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 28378358 Common - short chain dehydrogenase lp_1668 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 28377253 Nonpathogen - hypothetical protein lp_0333 1 None None None 28377587 Common - ABC transporter, ATP-binding protein lp_0723 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 28378610 Common era GTP-binding protein Era lp_1967 237 COG1159 Era, GTPase General function prediction only 28379642 Common cls cardiolipin synthetase 2 lp_3273 156 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 28379472 Common - amino acid transport protein lp_3049 90 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 28378103 Common - transcription regulator lp_1360 98 COG1846 MarR, Transcriptional regulators Transcription 28378827 Common - metal-dependent hydrolase of the beta-lactamase superfamily III (putative) lp_2229 73 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 28377396 Common - hypothetical protein lp_0507 46 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 28376980 Common gyrA DNA gyrase, A subunit lp_0007 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 28379026 Common - prophage Lp3 protein 15, terminase large subunit lp_2466 45 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 28379542 Common - hypothetical protein lp_3134 6 COG5294 COG5294, Uncharacterized protein conserved in bacteria Function unknown 28377519 Nonpathogen - prophage Lp1 protein 23 lp_0646 1 None None None 28377528 Nonpathogen - prophage Lp1 protein 32 lp_0655 1 None None None 28378053 Common - amino acid transport protein lp_1297 186 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 28377305 Common - transcription regulator lp_0396 103 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 28377512 Nonpathogen - prophage Lp1 protein 15 lp_0638 1 None None None 28376996 Common glgP glycogen phosphorylase lp_0024 142 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 28379904 Common - transcription regulator lp_3597 52 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 28378951 Common tdk thymidine kinase lp_2379 100 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 28378035 Common hpr phosphocarrier protein Hpr lp_1273 81 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 28377599 Common secA preprotein translocase subunit SecA lp_0739 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 28377944 Nonpathogen - hypothetical protein lp_1168 1 None None None 28379479 Common - hypothetical protein lp_3062 9 None None None 28377015 Common - hypothetical protein lp_0052 17 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 28378779 Common pgm6 phosphoglycerate mutase lp_2170 170 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 28378233 Common cshA1 recombination factor protein RarA lp_1519 245 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 28378871 Common alaS alanine--tRNA ligase lp_2277 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28378592 Nonpathogen - hypothetical protein lp_1946 1 None None None 28378587 Common nox4 NADH oxidase lp_1941 236 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 28377351 Common - NAD-dependent deacetylase lp_0449 147 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 28379966 Common - 2-oxo-hept-3-ene-1,7-dioate hydratase; 2-oxo-hept-4-ene-1,7-dioate hydratase lp_3666 60 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 28378693 Common - hypothetical protein lp_2062 8 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 28379464 Common - ABC transporter, permease protein (putative) lp_3038 5 None None None 28379940 Common hpk12 histidine protein kinase; sensor protein lp_3639 100 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 28377555 Nonpathogen - prophage Lp1 protein 60 lp_0683 2 COG5546 COG5546, Small integral membrane protein Function unknown 28378511 Common - GTPase lp_1854 119 COG1161 COG1161, Predicted GTPases General function prediction only 28378633 Nonpathogen - hypothetical protein lp_1992 2 None None None 28378869 Common - hypothetical protein lp_2275 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 28378495 Nonpathogen - hypothetical protein lp_1834 1 None None None 28377754 Common - integral membrane protein lp_0926 13 COG2261 COG2261, Predicted membrane protein Function unknown 28377654 Common glnQ1 glutamine ABC transporter, ATP-binding protein lp_0803 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 28379074 Common panE1 2-dehydropantoate 2-reductase lp_2532 99 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 28377061 Common - oxidoreductase lp_0111 194 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 28378706 Common - methyltransferase (putative) lp_2082 13 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 28377833 Common rplD 50S ribosomal protein L4 lp_1034 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 28379033 Common - prophage Lp3 protein 7 lp_2474 5 None None None 28377232 Common ack2 acetate kinase lp_0310 162 COG0282 ackA, Acetate kinase Energy production and conversion 28378444 Common - lysin lp_1767 6 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 28378299 Common nusB transcription antitermination protein NusB lp_1598 186 COG0781 NusB, Transcription termination factor Transcription 28377334 Common plnY plantaricin biosynthesis protein PlnY (putative) lp_0431 58 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 28377025 Common - nitroreductase lp_0062 77 COG0778 NfnB, Nitroreductase Energy production and conversion 28378636 Common - integrase, fragment lp_1997 107 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 28377603 Common rrp3 response regulator lp_0743 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 28378864 Common trxA2 thioredoxin lp_2270 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 28379887 Common nrpR5 negative regulator of proteolysis lp_3579 45 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 28377504 Nonpathogen - prophage Lp1 protein 7 lp_0630 3 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 28379197 Common pyrE orotate phosphoribosyltransferase lp_2697 156 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 28377412 Common carB carbamoyl-phosphate synthase, large subunit lp_0526 232 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 28377313 Nonpathogen plnJ bacteriocin precursor peptide PlnJ (putative) lp_0406 1 None None None 28379060 Common - transport protein lp_2514 150 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28379286 Common - transcription regulator lp_2804 74 COG0583 LysR, Transcriptional regulator Transcription 28379583 Common parB1 chromosome partitioning protein, DNA-binding protein lp_3198 187 COG1475 Spo0J, Predicted transcriptional regulators Transcription 28377238 Common potC spermidine/putrescine ABC transporter, permease protein lp_0316 163 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 28378309 Common opuC glycine betaine/carnitine/choline ABC transporter, substrate binding protein lp_1609 87 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 28379050 Common - sugar transport protein lp_2503 12 COG4975 GlcU, Putative glucose uptake permease Carbohydrate transport and metabolism 28378383 Nonpathogen - hypothetical protein lp_1694 1 None None None 28379511 Common - oxidoreductase (putative) lp_3098 123 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28377745 Nonpathogen - integral membrane protein lp_0915 1 None None None 28379559 Nonpathogen - hypothetical protein lp_3169 1 None None None 28377930 Common - transcription regulator (putative) lp_1153 12 COG1309 AcrR, Transcriptional regulator Transcription 28377968 Common - transposase, fragment (putative) lp_1194 5 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 28377994 Nonpathogen cps3G polysaccharide biosynthesis protein (putative) lp_1224 1 None None None 28377342 Common pbg1 6-phospho-beta-glucosidase lp_0440 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 28377194 Common tagF1 teichoic acid biosynthesis protein lp_0268 35 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 28377489 Common - hypothetical protein lp_0613 28 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 28378647 Common - transposase, fragment (putative) lp_2011 5 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 28379153 Nonpathogen - hypothetical protein lp_2636 1 None None None 28377249 Common acdH acetaldehyde dehydrogenase lp_0329 92 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 28378547 Common - integral membrane protein lp_1894 28 COG2707 COG2707, Predicted membrane protein Function unknown 28377860 Common ISP1 transposase lp_1064 49 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28377680 Nonpathogen - hypothetical protein lp_0835 1 None None None 28378995 Nonpathogen - prophage Lp2 protein 27 lp_2430 1 None None None 28379910 Common - hypothetical protein lp_3603 49 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 28377674 Common - transcription regulator (putative) lp_0825 9 COG1309 AcrR, Transcriptional regulator Transcription 28376989 Common proA glutamate-5-semialdehyde dehydrogenase lp_0017 190 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 28378915 Common - transcription regulator lp_2335 105 COG0640 ArsR, Predicted transcriptional regulators Transcription 28378274 Common pbp2B1 penicillin binding protein 2B lp_1568 191 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 28378410 Common - sugar transport protein (putative) lp_1729 40 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 28378784 Common ntpJ sodium ATP synthase, Na(+) translocating subunit J lp_2177 121 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 28379022 Nonpathogen - prophage Lp3 protein 20 lp_2461 1 None None None 28377709 Nonpathogen - hypothetical protein lp_0871 4 None None None 28379230 Common - L-asparaginase lp_2738 135 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 28379338 Common - oxidoreductase (putative) lp_2872 20 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 28377227 Common gcsH1 glycine cleavage system, H protein lp_0305 63 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 28378000 Nonpathogen - transcription regulator lp_1230 4 COG1846 MarR, Transcriptional regulators Transcription 28379598 Common - hypothetical protein lp_3218 8 None None None 28379711 Nonpathogen - hypothetical protein lp_3373 1 COG5562 COG5562, Phage envelope protein General function prediction only 28379147 Common pox3 pyruvate oxidase lp_2629 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 28379261 Common - ABC transporter, ATP-binding protein lp_2774 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28377979 Common cps2I repeat unit transporter lp_1205 17 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 28379803 Common galM3 aldose 1-epimerase lp_3487 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 28378140 Common argR1 arginine catabolic regulator lp_1411 74 COG1438 ArgR, Arginine repressor Transcription 28379735 Common - oxidoreductase lp_3403 190 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 28377531 Nonpathogen - prophage Lp1 protein 36 lp_0659 1 None None None 28377687 Common ppx3 exopolyphosphatase lp_0843 72 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 28377276 Nonpathogen - hypothetical protein lp_0361 1 None None None 28377116 Common malF maltose/maltodextrin ABC transporter, permease protein lp_0176 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 28378660 Common dnaK molecular chaperone DnaK lp_2027 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 28378942 Common atpF H(+)-transporting two-sector ATPase, B subunit lp_2368 181 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 28377093 Common - integral membrane protein lp_0150 15 COG4720 COG4720, Predicted membrane protein Function unknown 28378667 Common tyrA prephenate dehydrogenase lp_2034 149 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 28378532 Common hbsU DNA-binding protein II lp_1879 213 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 28377592 Common - transport protein lp_0729 63 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 28379268 Common - glycosyltransferase lp_2783 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 28377699 Common - redox protein, regulator of disulfide bond formation (putative) lp_0858 31 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 28379771 Nonpathogen - hypothetical protein lp_3448 2 None None None 28379518 Common fhuB ferrichrome ABC transporter, permease protein lp_3105 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 28376979 Common gyrB DNA gyrase, B subunit lp_0006 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 28377946 Common pbpX1 serine-type D-Ala-D-Ala carboxypeptidase lp_1171 103 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 28377046 Common pepI prolyl aminopeptidase lp_0088 107 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 28378977 Nonpathogen - prophage Lp2 protein 45 lp_2412 1 None None None 28378482 Common - L-lactate transport protein (putative) lp_1814 105 COG1620 LldP, L-lactate permease Energy production and conversion 28379524 Common - transcription regulator lp_3113 32 COG0789 SoxR, Predicted transcriptional regulators Transcription 28379190 Common - transport protein lp_2688 59 COG0730 COG0730, Predicted permeases General function prediction only 28379396 Common - esterase (putative) lp_2953 84 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 28379714 Nonpathogen - prophage Lp4 protein 13 lp_3377 1 None None None 28378892 Common - hypothetical protein lp_2306 19 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 28377780 Common pepD3 dipeptidase lp_0959 24 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 28377244 Common - acetyltransferase (putative) lp_0322 4 COG0456 RimI, Acetyltransferases General function prediction only 28379874 Common napA4 Na(+)/H(+) antiporter lp_3565 213 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 28378254 Common rrp5 response regulator lp_1544 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 28379012 Common - prophage Lp2 protein 8 lp_2449 3 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 28379971 Common sip3 signal peptidase I lp_3675 173 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 28378162 Nonpathogen - hypothetical protein lp_1440 2 None None None 28377867 Common - ABC transporter, ATP-binding protein lp_1073 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 28378005 Nonpathogen - hypothetical protein lp_1236 1 None None None 28379182 Common - multidrug transport protein, major facilitator superfamily lp_2675 95 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28378336 Common rimM 16S rRNA processing protein lp_1638 173 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 28378426 Common - amino acid ABC transporter, substrate binding protein lp_1746 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 28379849 Common tkt4 transketolase lp_3538 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 28377471 Common accC1 acetyl-CoA carboxylase, biotin carboxylase subunit lp_0590 226 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 28377382 Common - bifunctional protein: acetyl-glutamate kinase; acetyl-ornithine deacetylase (putative) lp_0488 51 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 28378687 Common - hydrolase, HAD superfamily lp_2056 106 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 28378553 Common clpB ATP-dependent Clp protease, ATP-binding subunit ClpB lp_1903 225 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 28379340 Common - short chain dehydrogenase lp_2874 188 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 28377133 Common - cell surface protein precursor lp_0197 18 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 28378192 Common fecD iron chelatin ABC transporter, permease protein lp_1476 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 28377702 Common - hypothetical protein lp_0862 7 None None None 28378372 Common - phosphopantetheinyltransferase lp_1682 26 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 28377854 Common infA translation initiation factor IF-1 lp_1059 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 28379219 Common purQ phosphoribosylformylglycinamidine synthase I lp_2725 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 28378835 Common - hypothetical protein lp_2236 11 COG4470 COG4470, Uncharacterized protein conserved in bacteria Function unknown 28377296 Nonpathogen - hypothetical protein lp_0383 1 None None None 28377913 Common cydD cytochrome D ABC transporter, ATP-binding and permease protein lp_1129 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 28378769 Nonpathogen - hypothetical protein lp_2156 2 None None None 28378130 Common pts15A beta-glucosides PTS, EIIA lp_1398 31 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 28377121 Common map2 maltose phosphorylase lp_0181 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 28379912 Common iolG1 myo-inositol 2-dehydrogenase lp_3605 185 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 28378819 Common rluD2 pseudouridylate synthase lp_2221 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 28379124 Common - transcription regulator lp_2597 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 28379621 Common - hypothetical protein lp_3245 3 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 28378290 Nonpathogen - hypothetical protein lp_1587 1 None None None 28378417 Nonpathogen - hypothetical protein lp_1736 1 None None None 28378075 Common - sugar ABC transporter, substrate binding protein (putative) lp_1327 87 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 28379573 Common - branched-chain amino acid transport protein lp_3185 95 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 28378539 Common - hypothetical protein lp_1886 7 COG4955 COG4955, Uncharacterized protein conserved in bacteria Function unknown 28378149 Common - transcription regulator lp_1422 158 COG0583 LysR, Transcriptional regulator Transcription 28378653 Common dltB D-alanyl transfer protein DltB lp_2018 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 28379567 Nonpathogen - integral membrane protein lp_3177 1 None None None 28378780 Common - extracellular protein lp_2173 7 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 28379409 Common - ABC transporter, ATP-binding protein lp_2972 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 28378249 Common ISP1 transposase lp_1537 49 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28378243 Common - hypothetical protein lp_1531 43 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 28376987 Common - transport protein lp_0015 79 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28378113 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase lp_1375 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 28379862 Common - hypothetical protein lp_3552 8 COG5506 COG5506, Uncharacterized conserved protein Function unknown 28379673 Common - hypothetical protein lp_3316 136 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 28378222 Common polA DNA-directed DNA polymerase I lp_1508 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 28379897 Common - hypothetical protein lp_3590 8 COG5506 COG5506, Uncharacterized conserved protein Function unknown 28377906 Common mleP2 malate transport protein lp_1119 132 COG0679 COG0679, Predicted permeases General function prediction only 28377831 Common rpsJ 30S ribosomal protein S10 lp_1032 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 28379406 Common - transcription regulator lp_2967 100 COG1846 MarR, Transcriptional regulators Transcription 28379465 Common - ABC transporter, ATP-binding protein lp_3040 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 28379653 Common - cation efflux protein lp_3288 174 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 28379009 Nonpathogen - prophage Lp2 protein 11 lp_2446 1 None None None 28378365 Common fabF 3-oxoacyl-[acyl-carrier protein] synthase II lp_1675 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 28377047 Common - hypothetical protein lp_0089 79 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 28377498 Common rplL ribosomal protein L12/L7 lp_0622 213 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 28379164 Common - hypothetical protein lp_2652 102 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 28378461 Nonpathogen - hypothetical protein lp_1788 5 None None None 28378185 Common - ABC transporter, ATP-binding protein lp_1468 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 28377652 Common - cell surface protein precursor lp_0800 61 None None None 28379413 Nonpathogen - cell surface protein precursor (putative) lp_2976 1 None None None 28379934 Common - hypothetical protein lp_3632 19 COG3538 COG3538, Uncharacterized conserved protein Function unknown 28377315 Nonpathogen plnN bacteriocin precursor peptide PlnN (putative) lp_0410 1 None None None 28378084 Common mrsA1 protein-methionine-S-oxide reductase lp_1339 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 28379259 Common - transcription regulator (putative) lp_2772 71 COG1309 AcrR, Transcriptional regulator Transcription 28377329 Common plnT integral membrane protein PlnT, membrane-bound protease CAAX family lp_0425 13 None None None 28377135 Common - lipoprotein precursor, peptide binding protein OppA homolog lp_0200 180 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 28377050 Nonpathogen - hypothetical protein lp_0096 1 None None None 28379612 Common - transcription regulator lp_3234 190 COG0583 LysR, Transcriptional regulator Transcription 28378045 Common - transposase lp_1288 49 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28379644 Common - amino acid transport protein lp_3278 184 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 28379546 Common - transcription regulator lp_3138 41 COG3711 BglG, Transcriptional antiterminator Transcription 28377080 Common - transport protein lp_0132 213 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28378070 Common pepV dipeptidase PepV lp_1321 155 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 28379094 Common hisD histidinol dehydrogenase lp_2559 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 28377173 Common pts3C cellobiose PTS, EIIC lp_0247 37 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 28379498 Common - transport protein lp_3082 131 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28378077 Common dgk2 deoxyguanosine kinase lp_1329 40 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 28378352 Common - oxidoreductase lp_1660 165 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 28378616 Common - hypothetical protein lp_1974 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 28377010 Common - hypothetical protein lp_0045 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 28379636 Common gshR4 glutathione reductase lp_3267 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 28379695 Nonpathogen - hypothetical protein lp_3348 1 None None None 28377361 Common - cell surface hydrolase, membrane-bound (putative) lp_0461 63 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 28379069 Common - ABC transporter, ATP-binding protein lp_2525 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 28377017 Common - hypothetical protein lp_0054 13 None None None 28379053 Common rrp7 response regulator lp_2506 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 28378251 Common - cation transport protein lp_1540 10 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 28378111 Common - integral membrane protein lp_1373 2 None None None 28378403 Nonpathogen - hypothetical protein lp_1717 1 None None None 28379692 Common - transcription regulator lp_3344 45 COG1846 MarR, Transcriptional regulators Transcription 28378701 Common - transcription regulator lp_2075 59 COG1316 LytR, Transcriptional regulator Transcription 28378537 Nonpathogen - hypothetical protein lp_1884 2 None None None 28378034 Common clpE ATP-dependent Clp protease, ATP-binding subunit ClpE lp_1269 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 28377035 Common - hypothetical protein lp_0073 112 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 28378026 Common - integral membrane protein lp_1260 5 COG4272 COG4272, Predicted membrane protein Function unknown 28377506 Common - prophage Lp1 protein 9 lp_0632 3 COG1476 COG1476, Predicted transcriptional regulators Transcription 28379750 Common pck phosphoenolpyruvate carboxykinase (ATP) lp_3418 19 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 28379184 Common - oxidoreductase lp_2677 193 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 28377187 Nonpathogen - integral membrane protein lp_0261 1 None None None 28379963 Common - hypothetical protein lp_3663 9 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 28379701 Common - oxidoreductase (putative) lp_3355 42 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28378604 Nonpathogen - hypothetical protein lp_1961 1 None None None 28379382 Common nrdD anaerobic ribonucleoside triphosphate reductase lp_2932 94 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 28379777 Nonpathogen - hypothetical protein lp_3454 1 None None None 28379587 Common nupC nucleoside transport protein lp_3204 67 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 28377101 Common - ABC transporter, ATP-binding protein lp_0160 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28378747 Common holA DNA polymerase III subunit delta lp_2128 72 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 28379686 Nonpathogen - hypothetical protein lp_3337 1 None None None 28378010 Common - hypothetical protein lp_1241 17 COG3557 COG3557, Uncharacterized domain/protein associated with RNAses G and E Translation, ribosomal structure and biogenesis 28377175 Common - hypothetical protein lp_0249 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 28378789 Nonpathogen - hypothetical protein lp_2182 1 None None None 28377191 Common pts5ABC beta-glucosides PTS, EIIABC lp_0265 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28379853 Common - multidomain protein lp_3542 39 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 28379669 Nonpathogen - integral membrane protein lp_3310 2 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 28378333 Common ffh signal recognition particle protein Ffh lp_1635 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 28377796 Common thrA1 aspartate kinase I lp_0979 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 28379850 Common tal2 putative translaldolase lp_3539 161 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 28377887 Common mtsB manganese ABC transporter, permease protein lp_1096 195 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 28377696 Common birA2 biotin--[acetyl-CoA-carboxylase] ligase and biotin operon repressor lp_0854 217 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 28377140 Common pgm1 phosphoglycerate mutase (putative) lp_0205 130 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 28379368 Common - integral membrane protein lp_2917 5 None None None 28377890 Common ldh L-lactate dehydrogenase lp_1101 174 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 28379118 Common - nitroreductase lp_2590 70 COG0778 NfnB, Nitroreductase Energy production and conversion 28379372 Common - integral membrane protein lp_2921 71 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 28378555 Common - hypothetical protein lp_1905 83 COG0327 COG0327, Uncharacterized conserved protein Function unknown 28378721 Common cps4J repeat unit transporter lp_2099 34 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 28377649 Common - carboxylesterase lp_0796 24 COG1647 COG1647, Esterase/lipase General function prediction only 28378936 Common murA2 UDP-N-acetylglucosamine 1-carboxyvinyltransferase lp_2361 216 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 28378278 Common glk glucokinase lp_1573 145 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 28379570 Nonpathogen - integral membrane protein lp_3180 1 None None None 28377180 Common cysE serine O-acetyltransferase lp_0254 198 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 28378428 Common - ABC transporter, permease protein lp_1748 198 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 28378101 Nonpathogen - integral membrane protein lp_1358 1 None None None 28377389 Common - fucose transport protein lp_0498 49 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 28379592 Common - amino acid ABC transporter, permease protein lp_3210 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 28378563 Common - transcription regulator lp_1914 56 COG1846 MarR, Transcriptional regulators Transcription 28379043 Common - cell surface protein precursor, GY family lp_2486 144 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 28379326 Common - ABC transporter, permease protein (putative) lp_2856 60 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 28379513 Common - oxidoreductase lp_3100 193 COG4989 COG4989, Predicted oxidoreductase General function prediction only 28377464 Common - hypothetical protein lp_0583 10 COG4687 COG4687, Uncharacterized protein conserved in bacteria Function unknown 28379279 Common - cell surface protein precursor lp_2796 12 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 28379826 Common - hypothetical protein lp_3510 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 28379486 Common - oxidoreductase lp_3069 168 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 28379245 Common - glucan 1,4-alpha-maltohydrolase lp_2757 169 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 28377975 Common cps2E priming glycosyltransferase lp_1201 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 28378752 Common kdtB pantetheine-phosphate adenylyltransferase lp_2133 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 28378199 Common - hypothetical protein lp_1483 5 None None None 28379305 Common mleP3 malate transport protein (putative) lp_2829 140 COG0679 COG0679, Predicted permeases General function prediction only 28379398 Common - hypothetical protein lp_2956 6 COG0657 Aes, Esterase/lipase Lipid metabolism 28379651 Common hly hemolysin III lp_3286 118 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 28379424 Common - transcription regulator lp_2991 18 COG1396 HipB, Predicted transcriptional regulators Transcription 28379957 Common srlD2 sorbitol-6-phosphate 2-dehydrogenase lp_3657 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 28378792 Common ileS isoleucine--tRNA ligase lp_2187 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28377431 Common ftsH cell division protein FtsH, ATP-dependent zinc metallopeptidase lp_0547 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 28379729 Common - cell surface hydrolase, membrane-bound (putative) lp_3393 54 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 28378764 Common pdhD dihydrolipoamide dehydrogenase lp_2151 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 28379531 Common - Na(+)/H(+) antiporter lp_3122 130 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 28378624 Common lytH N-acetylmuramoyl-L-alanine amidase lp_1982 175 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 28378092 Common nox6 NADH oxidase lp_1350 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 28377722 Common - transcription regulator lp_0889 98 COG1846 MarR, Transcriptional regulators Transcription 28379937 Common msmK2 multiple sugar ABC transporter, ATP-binding protein lp_3635 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 28378984 Common - prophage Lp2 protein 38 lp_2419 4 None None None 28378883 Common mutL DNA mismatch repair protein lp_2297 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 28377562 Common nrdE ribonucleotide-diphosphate reductase subunit alpha lp_0693 216 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 28378626 Common - hydrolase, HAD superfamily lp_1985 26 COG0546 Gph, Predicted phosphatases General function prediction only 28377876 Common tkt2 transketolase lp_1083 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 28379280 Nonpathogen - hypothetical protein lp_2797 1 None None None 28378841 Common - type I restriction-modification system methyltransferase subunit (putative) lp_2243 10 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 28377406 Common murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamino pimelate--D-alanyl-D-alanine ligase lp_0518 211 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 28377928 Common - putative lipid kinase lp_1150 112 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 28378473 Common - integral membrane protein lp_1801 6 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 28378099 Common pltR response regulator lp_1356 23 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 28379201 Common pyrAA carbamoyl phosphate synthase small subunit lp_2701 237 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 28379084 Common hibD 3-hydroxyisobutyrate dehydrogenase lp_2548 179 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 28378506 Common codV integrase/recombinase lp_1847 229 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 28379732 Common - hypothetical protein lp_3397 9 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 28377141 Common - oxidoreductase lp_0206 164 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 28377633 Common - integral membrane protein lp_0778 8 COG3247 HdeD, Uncharacterized conserved protein Function unknown 28377779 Common asnA asparagine synthetase AsnA lp_0957 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 28377155 Common greA transcription elongation factor GreA lp_0223 199 COG0782 GreA, Transcription elongation factor Transcription 28379585 Common parB2 chromosome partitioning protein, DNA-binding protein lp_3200 185 COG1475 Spo0J, Predicted transcriptional regulators Transcription 28377059 Common glpF1 glycerol uptake facilitator protein lp_0108 118 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 28377487 Common - hypothetical protein lp_0611 37 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 28379296 Common - proton/sodium-glutamate symport protein lp_2818 165 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 28377077 Common hsp1 small heat shock protein lp_0129 138 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 28378379 Common - integral membrane protein lp_1690 49 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 28378678 Common polC DNA-directed DNA polymerase III, alpha chain PolC-type lp_2045 216 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 28378284 Common glnR glutamine synthetase repressor lp_1580 42 COG0789 SoxR, Predicted transcriptional regulators Transcription 28379132 Common - oxidoreductase lp_2606 153 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 28378923 Common ddl D-alanine--D-alanine ligase lp_2345 213 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 28377996 Common cps3I O-acetyltransferase lp_1226 14 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 28378825 Common mecA adaptor protein lp_2227 14 COG4862 MecA, Negative regulator of genetic competence, sporulation and motility Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion 28379295 Common - transcription regulator of multidrug-efflux transporter lp_2817 84 COG0789 SoxR, Predicted transcriptional regulators Transcription 28378530 Common - hydrolase, HAD superfamily, Cof family lp_1876 101 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28379840 Common pbg10 6-phospho-beta-glucosidase lp_3526 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 28377072 Common pacL1 cation transporting P-type ATPase lp_0124 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 28378800 Common murG N-acetylglucosaminyl transferase lp_2196 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 28377521 Nonpathogen - prophage Lp1 protein 25 lp_0648 1 None None None 28377147 Nonpathogen - integral membrane protein lp_0214 1 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 28379108 Common - integral membrane protein lp_2575 11 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 28378064 Common - methyltransferase (putative) lp_1314 28 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 28377517 Nonpathogen - prophage Lp1 protein 21 lp_0644 1 None None None 28377942 Common - cell surface hydrolase (putative) lp_1165 9 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 28379540 Common pbg7 6-phospho-beta-glucosidase lp_3132 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 28379579 Common prtM2 peptidylprolyl isomerase lp_3193 15 None None None 28379814 Common aroD3 shikimate 5-dehydrogenase lp_3498 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 28378717 Common fruR transcription regulator of fructose operon lp_2095 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 28378326 Common recG ATP-dependent DNA helicase RecG lp_1627 223 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 28378902 Common - DNA repair protein lp_2320 173 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 28377761 Nonpathogen - hypothetical protein lp_0934 1 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 28377207 Common rrp2 response regulator lp_0283 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 28377732 Common pgm3 phosphoglycerate mutase lp_0900 149 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 28378150 Common - oxidoreductase (putative) lp_1424 108 COG0431 COG0431, Predicted flavoprotein General function prediction only 28378468 Common - DegV family protein lp_1796 52 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 28378545 Common - integrase/recombinase lp_1892 233 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 28377929 Common - RNA methyltransferase lp_1151 199 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 28377804 Common - multidrug transport protein lp_0991 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377455 Common - hypothetical protein lp_0574 6 COG4990 COG4990, Uncharacterized protein conserved in bacteria Function unknown 28377574 Common - methyltransferase (putative) lp_0707 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 28379664 Common - integral membrane protein (putative) lp_3301 12 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 28379834 Common pts32A glucose PTS, EIIA lp_3520 59 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 28379356 Nonpathogen - integral membrane protein lp_2900 1 None None None 28377222 Common - ABC transporter, ATP-binding protein lp_0299 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 28378211 Common moaB molybdopterin biosynthesis protein MoaB lp_1495 158 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 28378986 Common - prophage Lp2 protein 36 lp_2421 15 COG1783 XtmB, Phage terminase large subunit General function prediction only 28377553 Common - prophage Lp1 protein 58, lysin lp_0681 10 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 28377438 Common - hypothetical protein lp_0555 2 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 28379228 Common cah carbonate dehydratase lp_2736 52 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 161501980 Common - hypothetical protein lp_2508 36 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 28379865 Common araD L-ribulose-5-phosphate 4-epimerase lp_3555 130 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 28379617 Common pts28ABC beta-glucosides PTS, EIIABC lp_3240 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28379111 Common - alkaline phosphatase superfamily protein lp_2580 36 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 28377712 Nonpathogen - hypothetical protein lp_0875 2 None None None 28379929 Common - sugar transport protein lp_3626 53 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 28377752 Common - hypothetical protein lp_0924 5 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 28379174 Common rrp8 response regulator lp_2665 15 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 28379509 Common - short-chain dehydrogenase/oxidoreductase lp_3096 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 28377320 Common plnB histidine protein kinase PlnB; sensor protein lp_0416 31 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 28377661 Common - DNA-directed DNA polymerase III, epsilon chain (putative) lp_0811 168 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 28378816 Common pts17A glucitol/sorbitol PTS, EIIA lp_2218 5 COG3731 SrlB, Phosphotransferase system sorbitol-specific component IIA Carbohydrate transport and metabolism 28379949 Common - ABC transporter, ATP-binding and permease protein lp_3648 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 28378015 Common - transport protein lp_1247 144 COG0628 PerM, Predicted permease General function prediction only 28379844 Common - transcription regulator lp_3531 126 COG1609 PurR, Transcriptional regulators Transcription 28378137 Common - aminotransferase with N-terminal regulator domain lp_1407 224 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 28379303 Common napA3 Na(+)/H(+) antiporter lp_2827 211 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 28379502 Common hpk10 histidine protein kinase; sensor protein lp_3088 9 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 28377216 Common - GTP pyrophosphokinase (putative) lp_0293 134 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 28379538 Nonpathogen - hypothetical protein lp_3130 1 None None None 28377818 Common lysP lysine transport protein lp_1008 160 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 28378344 Common trpE anthranilate synthase, component I lp_1652 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 28377821 Common serS2 seryl-tRNA synthetase lp_1012 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 28379769 Common - transcription regulator lp_3444 179 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 28379121 Common - sugar transport protein lp_2594 11 COG4975 GlcU, Putative glucose uptake permease Carbohydrate transport and metabolism 28377384 Common - transport protein lp_0492 147 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 28378446 Nonpathogen - transport protein lp_1770 1 None None None 28379909 Nonpathogen - hypothetical protein lp_3602 1 None None None 28377473 Common accA1 acetyl-CoA carboxylase, carboxyl transferase subunit alpha lp_0592 179 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 28379052 Common hpk7 histidine protein kinase; sensor protein lp_2505 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 28379035 Nonpathogen - prophage Lp3 protein 5 lp_2476 1 None None None 28377611 Common - stress-responsive transcription regulator (putative) lp_0752 30 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 28379010 Common - prophage Lp2 protein 10 lp_2447 7 COG1476 COG1476, Predicted transcriptional regulators Transcription 28377772 Nonpathogen - hypothetical protein lp_0949 2 COG1396 HipB, Predicted transcriptional regulators Transcription 28378067 Common - integral membrane protein lp_1317 35 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 28377336 Common - hypothetical protein lp_0433 211 COG0388 COG0388, Predicted amidohydrolase General function prediction only 28377234 Common - transcription regulator lp_0312 18 COG1846 MarR, Transcriptional regulators Transcription 28377958 Common cps1H glycosyltransferase (rhamnosyltransferase) lp_1184 141 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 28379786 Common lacA beta-galactosidase I lp_3469 39 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 28377239 Common potB spermidine/putrescine ABC transporter, permease protein lp_0317 204 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 28378204 Common hpk4 histidine protein kinase; sensor protein (putative) lp_1488 140 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 28379298 Common - ABC transporter, permease protein (putative) lp_2822 15 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 28377789 Common - integral membrane protein lp_0969 9 COG5438 COG5438, Predicted multitransmembrane protein Function unknown 28377415 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein lp_0529 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 28379762 Nonpathogen - hypothetical protein lp_3433 5 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 28378862 Common murI glutamate racemase lp_2268 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 28379284 Common - oxidoreductase lp_2802 164 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 28378907 Common thiI thiamine biosynthesis protein ThiI lp_2325 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 28377311 Common plnL immunity protein PlnL lp_0404 2 None None None 28378940 Common atpA F0F1 ATP synthase subunit alpha lp_2366 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 28377466 Common - transcription regulator lp_0585 154 COG3933 COG3933, Transcriptional antiterminator Transcription 28378315 Common priA primosomal protein N' lp_1615 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 28379203 Common pyrB aspartate carbamoyltransferase catalytic subunit lp_2703 239 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 28379031 Nonpathogen - prophage Lp3 protein 9 lp_2472 1 None None None 28379605 Common - ABC transporter, ATP-binding protein lp_3225 249 COG4619 COG4619, ABC-type uncharacterized transport system, ATPase component General function prediction only 28378389 Common tspO sensory protein lp_1700 59 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 28378997 Nonpathogen - prophage Lp2 protein 25 lp_2432 1 None None None 28377719 Common pts11BC beta-glucosides PTS, EIIBC lp_0886 45 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28377842 Common rplN ribosomal protein L14 lp_1045 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 28377932 Common pts13C cellobiose PTS, EIIC lp_1155 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 28379793 Common fic cell filamentation protein Fic lp_3477 33 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 28379144 Nonpathogen - hypothetical protein lp_2623 4 None None None 28379156 Nonpathogen - integral membrane protein lp_2642 1 None None None 28378858 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase lp_2264 187 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 28377003 Nonpathogen - hypothetical protein lp_0032 2 None None None 28379361 Common - acetyltransferase (putative) lp_2907 16 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 28378165 Common npr1 NADH peroxidase lp_1445 243 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 28378235 Common - transcription regulator (putative) lp_1522 144 COG1733 COG1733, Predicted transcriptional regulators Transcription 28379902 Common rhaB rhamnulokinase lp_3595 84 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 28379374 Common - lipase/esterase (putative) lp_2923 35 COG0657 Aes, Esterase/lipase Lipid metabolism 28377394 Common sdhB L-serine dehydratase, beta subunit lp_0505 24 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 28377966 Common - transposase, fragment (putative) lp_1192 77 None None None 28377707 Common - metal uptake regulator lp_0868 135 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 28379837 Common murQ N-acetylmuramic acid-6-phosphate etherase lp_3523 83 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 28377602 Common - integral membrane protein lp_0742 5 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 28377791 Common - alpha-ribazole-5'-phosphate phosphatase (putative) lp_0971 151 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 28377980 Common cps2J glycosyltransferase lp_1206 199 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28377739 Common - DedA protein lp_0907 161 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 28378877 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase lp_2285 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 28378562 Common - hypothetical protein lp_1913 3 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 28377526 Common - prophage Lp1 protein 30 lp_0653 8 None None None 28377581 Common phnC phosphonates ABC transporter, ATP-binding protein lp_0714 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 28377013 Common - hypothetical protein lp_0048 56 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 28378030 Common oppD oligopeptide ABC transporter, ATP-binding protein lp_1264 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 28378581 Common - transcription regulator lp_1934 70 COG1737 RpiR, Transcriptional regulators Transcription 28378051 Common mntH3 cation transport protein lp_1295 87 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 28377358 Common ksgA dimethyladenosine transferase lp_0458 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 28378230 Common rpmI ribosomal protein L35 lp_1516 109 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 28377349 Common mvaA hydroxymethylglutaryl-CoA reductase lp_0447 33 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 28377510 Nonpathogen - prophage Lp1 protein 13 lp_0636 1 None None None 28379564 Common cfa2 cyclopropane-fatty-acyl-phospholipid synthase lp_3174 136 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 28376994 Common glgD glucose-1-phosphate adenylyltransferase, subunit lp_0022 120 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 28378029 Common oppC oligopeptide ABC transporter, permease protein lp_1263 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 28379901 Common - hypothetical protein lp_3594 44 COG3254 COG3254, Uncharacterized conserved protein Function unknown 28379649 Common qacC quaternary ammonium compound-resistance protein lp_3284 136 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 28378576 Common - hypothetical protein lp_1929 8 COG3272 COG3272, Uncharacterized conserved protein Function unknown 28378438 Common - lipase/esterase (putative) lp_1760 18 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 28378177 Common - methyl transferase (putative) lp_1458 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 28378573 Common - transcription regulator lp_1926 110 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 28379968 Common - DegV family protein lp_3669 51 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 28377374 Common rpoE DNA-directed RNA polymerase subunit delta lp_0480 14 COG3343 RpoE, DNA-directed RNA polymerase, delta subunit Transcription 28378579 Common gph2 phosphoglycolate phosphatase lp_1932 126 COG0546 Gph, Predicted phosphatases General function prediction only 28377843 Common rplX ribosomal protein L24 lp_1046 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 28378458 Common pgm5 phosphoglycerate mutase (putative) lp_1785 131 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 28377123 Common - integral membrane protein lp_0183 10 None None None 28377509 Common - prophage Lp1 protein 12 lp_0635 12 COG1476 COG1476, Predicted transcriptional regulators Transcription 28378356 Common adh1 alcohol dehydrogenase lp_1665 206 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 28378650 Common lepA1 GTP-binding protein LepA lp_2015 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 28377623 Common - protein containing diguanylate cyclase/phosphodiesterase domain 2 (EAL) lp_0765 123 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 28378338 Common rplS 50S ribosomal protein L19 lp_1640 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 28378397 Nonpathogen - integral membrane protein lp_1709 1 None None None 28378631 Common - ribosomal protein L11 methyltransferase (putative) lp_1990 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 28378088 Nonpathogen - hypothetical protein lp_1345 1 None None None 28378614 Common - hypothetical protein lp_1972 156 COG1610 COG1610, Uncharacterized conserved protein Function unknown 28378374 Common - transcription regulator lp_1685 185 COG0583 LysR, Transcriptional regulator Transcription 28378493 Common - integral membrane protein lp_1825 6 None None None 28377835 Common rplB 50S ribosomal protein L2 lp_1036 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 28377918 Common acm1 muramidase lp_1138 67 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 28377700 Nonpathogen - transposase, fragment lp_0860 1 None None None 28377852 Common secY preprotein translocase subunit SecY lp_1056 233 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 28378775 Common ISP1 transposase lp_2164 49 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28377915 Common hepB2 trans-hexaprenyltranstransferase, component II lp_1134 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 28378898 Common minC septum site-determining protein MinC lp_2316 14 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 28377717 Common pts11A PTS, EIIA (putative) lp_0884 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 28377538 Nonpathogen - prophage Lp1 protein 43 lp_0666 3 None None None 28379237 Common - hypothetical protein lp_2745 79 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 28377825 Common rpoB DNA-directed RNA polymerase subunit beta lp_1021 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 28379740 Common - hypothetical protein lp_3408 115 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 28378323 Common rpmB ribosomal protein L28 lp_1624 38 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 28378767 Common pdhA pyruvate dehydrogenase complex, E1 component, alpha subunit lp_2154 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 28376985 Common rplI 50S ribosomal protein L9 lp_0013 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 28377682 Nonpathogen - hypothetical protein lp_0837 1 None None None 28377294 Common - hypothetical protein lp_0381 9 None None None 28377082 Common - transport protein lp_0134 76 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 28379328 Common thgA3 galactoside O-acetyltransferase lp_2861 81 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 28379943 Common - sugar ABC transporter, substrate binding protein lp_3642 9 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 28378833 Common - integral membrane protein lp_2234 9 COG4478 COG4478, Predicted membrane protein Function unknown 28379408 Common pts22CBA N-acetylglucosamine PTS, EIICBA lp_2969 58 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28378645 Common - transposase, fragment lp_2009 5 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28377747 Common - hypothetical protein lp_0918 60 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 28379122 Common - sugar kinase and transcription regulator lp_2595 145 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 28377656 Common - hydrolase, HAD superfamily, Cof family lp_0805 118 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28377200 Common mntH1 manganese transport protein lp_0275 97 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 28378041 Common araT1 aromatic amino acid aminotransferase lp_1280 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 28379263 Common pbg4 6-phospho-beta-glucosidase lp_2777 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 28377590 Common groES co-chaperonin GroES lp_0727 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 28379792 Common - transcription regulator lp_3476 59 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 28378265 Common pheS phenylalanine--tRNA ligase, alpha chain lp_1558 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 28379871 Common - lipase/esterase (putative) lp_3561 34 COG0657 Aes, Esterase/lipase Lipid metabolism 28379469 Common - short-chain dehydrogenase/oxidoreductase lp_3045 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 28377643 Common pgk phosphoglycerate kinase lp_0790 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 28378245 Common - methyltransferase (putative) lp_1533 109 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 28377909 Common - cell surface hydrolase lp_1124 21 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 28377211 Nonpathogen - hypothetical protein lp_0287 1 None None None 28379057 Nonpathogen - hypothetical protein lp_2510 1 None None None 28379675 Common - hypothetical protein lp_3319 44 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 28377491 Common rpmG 50S ribosomal protein L33 lp_0615 59 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 28379720 Common - prophage Lp4 protein 7, DNA replication lp_3383 12 None None None 28377114 Common agl1 alpha-glucosidase lp_0174 169 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 28379345 Common - hypothetical protein lp_2880 2 None None None 28377724 Common - transcription regulator (putative) lp_0892 16 COG1846 MarR, Transcriptional regulators Transcription 28377251 Common - sugar transport protein lp_0331 78 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 28379932 Common - sugar kinase and transcription regulator lp_3630 165 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 28378925 Common - hypothetical protein lp_2347 11 None None None 28379716 Common - prophage Lp4 protein 11, DNA replication lp_3379 3 None None None 28377087 Common - hypothetical protein lp_0139 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 28377132 Common - transcription regulator lp_0194 171 COG0583 LysR, Transcriptional regulator Transcription 28379028 Common - prophage Lp3 protein 12 lp_2469 27 None None None 28377263 Nonpathogen - integral membrane protein lp_0346 1 None None None 28377478 Nonpathogen zmp2 extracellular zinc metalloproteinase (putative) lp_0600 1 COG1913 COG1913, Predicted Zn-dependent proteases General function prediction only 28378534 Common engA GTP-binding protein EngA lp_1881 222 COG1160 COG1160, Predicted GTPases General function prediction only 28379216 Common purM phosphoribosylaminoimidazole synthetase lp_2722 231 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 28378782 Nonpathogen - extracellular protein lp_2175 2 None None None 28379116 Common - cell surface protein precursor lp_2588 3 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 28377597 Common comFC late competence protein lp_0736 38 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 28379580 Common - integral membrane protein lp_3195 8 COG4858 COG4858, Uncharacterized membrane-bound protein conserved in bacteria Function unknown 28379628 Common lrgA effector of murein hydrolase (putative) lp_3254 27 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 28377692 Common pox1 pyruvate oxidase lp_0849 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 28378524 Common dfrA dihydrofolate reductase lp_1869 145 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 28377445 Common - transcription regulator lp_0563 157 COG2188 PhnF, Transcriptional regulators Transcription 28377865 Common - lipoprotein precursor lp_1070 10 COG4939 COG4939, Major membrane immunogen, membrane-anchored lipoprotein Function unknown 28378639 Common - hypothetical protein lp_2002 2 None None None 28379076 Common hom1 homoserine dehydrogenase lp_2535 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 28378007 Nonpathogen - hypothetical protein lp_1238 2 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 28378095 Common - hydrolase, HAD superfamily, Cof family lp_1353 96 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28378297 Common efp elongation factor P lp_1596 219 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 28378975 Nonpathogen - prophage Lp2 protein 47 lp_2410 1 None None None 28378419 Common - hypothetical protein lp_1738 5 COG5353 COG5353, Uncharacterized protein conserved in bacteria Function unknown 28378484 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase lp_1816 191 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 28378412 Common galM2 aldose 1-epimerase lp_1731 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 28379922 Common pts37A sorbitol PTS, EIIA lp_3618 21 COG3731 SrlB, Phosphotransferase system sorbitol-specific component IIA Carbohydrate transport and metabolism 28377044 Common - transcription regulator lp_0083 40 COG0640 ArsR, Predicted transcriptional regulators Transcription 28377179 Common kdgK 2-keto-3-deoxygluconate kinase lp_0253 54 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 28378500 Common parC DNA topoisomerase IV subunit A lp_1839 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 28378424 Common - amino acid ABC transporter, ATP-binding protein lp_1744 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 28378470 Common - integral membrane protein lp_1798 10 COG5523 COG5523, Predicted integral membrane protein Function unknown 28377689 Common - transcription regulator lp_0845 11 COG1846 MarR, Transcriptional regulators Transcription 28378263 Common - hypothetical protein lp_1556 11 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 28377838 Common rpsC 30S ribosomal protein S3 lp_1040 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 28379708 Common copR transcription regulator lp_3365 30 COG3682 COG3682, Predicted transcriptional regulator Transcription 28378685 Common tsf elongation factor Ts lp_2054 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 28379828 Common pts30BCA beta-glucosides PTS, EIIBCA lp_3513 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28378071 Common - hypothetical protein lp_1322 78 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 28377889 Nonpathogen - hypothetical protein lp_1098 2 None None None 28378040 Common dacA2 serine-type D-Ala-D-Ala carboxypeptidase lp_1278 142 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 28378118 Common astA arylsulfate sulfotransferase lp_1381 11 None None None 28377145 Nonpathogen - hypothetical protein lp_0211 1 None None None 28379596 Common - transcription regulator (putative) lp_3216 46 COG1695 COG1695, Predicted transcriptional regulators Transcription 28378602 Common - transcription regulator lp_1959 85 COG1725 COG1725, Predicted transcriptional regulators Transcription 28378745 Common rpsO ribosomal protein S15 lp_2125 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 28377969 Nonpathogen - transposase, fragment (putative) lp_1195 1 None None None 28377453 Common hom2 homoserine dehydrogenase lp_0571 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 28379267 Common - transcription regulator lp_2782 86 COG2188 PhnF, Transcriptional regulators Transcription 28377027 Nonpathogen - hypothetical protein lp_0064 1 None None None 28379667 Nonpathogen - hypothetical protein lp_3305 1 None None None 28378331 Common ftsY signal recognition particle receptor FtsY lp_1633 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 28378831 Common ppiB peptidylprolyl isomerase lp_2231c 198 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 28378258 Common sbcD exonuclease SbcD lp_1549 118 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 28378507 Common gidC tRNA (uracil-5-)-methyltransferase Gid lp_1848 185 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 28378543 Common - hypothetical protein lp_1890 142 COG1354 COG1354, Uncharacterized conserved protein Function unknown 28379086 Common maa1 maltose O-acetyltransferase lp_2550 118 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 28378209 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein MobB lp_1493 91 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 28379855 Common gph3 phosphoglycolate phosphatase (putative) lp_3544 137 COG0546 Gph, Predicted phosphatases General function prediction only 28379876 Common - sugar kinase and transcription regulator lp_3567 94 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 28378758 Common ica2 glycosyltransferase (putative) lp_2142 148 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 28378851 Common ccpA catabolite control protein A lp_2256 128 COG1609 PurR, Transcriptional regulators Transcription 28377560 Common - hypothetical protein lp_0691 116 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 28379436 Common pts23A cellobiose PTS, EIIA lp_3008 12 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 28379307 Common - transport protein lp_2833 64 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377816 Common - transcription regulator (putative) lp_1004 75 COG1959 COG1959, Predicted transcriptional regulator Transcription 28377493 Common nusG transcription antitermination protein NusG lp_0617 215 COG0250 NusG, Transcription antiterminator Transcription 28379774 Common - cell surface protein precursor lp_3451 8 None None None 28377425 Common - integral membrane protein lp_0540 27 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 28379270 Nonpathogen - hypothetical protein lp_2786 1 None None None 28379456 Nonpathogen - integral membrane protein lp_3028 1 None None None 28377659 Common - ATPase or kinase (putative) lp_0809 191 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 28379247 Common - hydrolase, HAD superfamily, Cof family lp_2759 116 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28379852 Common pts34B PTS, EIIB lp_3541 27 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 28379608 Common - metal-dependent hydrolase (putative) lp_3228 27 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 28379277 Common - flavodoxin lp_2794 42 COG0716 FldA, Flavodoxins Energy production and conversion 28379846 Common agl5 alpha-glucosidase lp_3534 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 28377367 Common prs1 ribose-phosphate pyrophosphokinase lp_0471 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 28377543 Nonpathogen - prophage Lp1 protein 48 lp_0671 1 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 28379384 Common def2 peptide deformylase lp_2935 176 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 28378089 Common asd1 aspartate-semialdehyde dehydrogenase lp_1346 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 28377679 Common glpK glycerol kinase lp_0834 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 28379924 Common pts37C sorbitol PTS, EIIC lp_3620 22 COG3730 SrlA, Phosphotransferase system sorbitol-specific component IIC Carbohydrate transport and metabolism 28379067 Nonpathogen - hypothetical protein lp_2523 1 None None None 28378514 Common - transcription regulator lp_1857 177 COG0583 LysR, Transcriptional regulator Transcription 28378622 Common aspS aspartyl-tRNA synthetase lp_1980 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28378082 Common - ABC transporter, ATP-binding protein lp_1335 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28379300 Common - integral membrane protein lp_2824 18 None None None 28379821 Common est2 acetylesterase lp_3505 104 COG0627 COG0627, Predicted esterase General function prediction only 28377440 Common - hypothetical protein lp_0557 40 None None None 28379591 Common - amino acid ABC transporter, substrate binding protein lp_3209 176 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 28378726 Common cps4E priming glycosyltransferase lp_2104 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 28378028 Common oppB oligopeptide ABC transporter, permease protein lp_1262 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 28378047 Common - integral membrane protein lp_1290 3 COG2252 COG2252, Permeases General function prediction only 28378366 Common accB2 acetyl-CoA carboxylase, biotin carboxyl carrier protein lp_1676 191 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 28378187 Common csd1 cysteine desulfurase lp_1470 238 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 28377895 Common citD citrate lyase subunit gamma lp_1107 25 COG3052 CitD, Citrate lyase, gamma subunit Energy production and conversion 28379768 Common - hypothetical protein lp_3442 30 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 28377095 Common - transcription regulator lp_0152 117 COG2188 PhnF, Transcriptional regulators Transcription 28378823 Common pepF1 oligoendopeptidase F lp_2225 84 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 28378722 Common cps4I glycosyltransferase lp_2100 169 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 28379610 Nonpathogen - hypothetical protein lp_3232 7 None None None 28378695 Nonpathogen - hypothetical protein lp_2066 2 None None None 28379257 Common - hypothetical protein lp_2770 15 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 28378956 Nonpathogen - hypothetical protein lp_2388 1 None None None 28378466 Common - adherence protein lp_1793 74 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 28378737 Common - GTPase EngB lp_2115 186 COG0218 COG0218, Predicted GTPase General function prediction only 28379331 Nonpathogen - integral membrane protein lp_2864 1 None None None 28379002 Common - prophage Lp2 protein 20 lp_2437 2 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 28378550 Common dnaE DNA-directed DNA polymerase III, alpha chain lp_1899 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 28379496 Common - integral membrane protein lp_3080 6 None None None 28379311 Common - ribosomal protein acetylating enzyme lp_2840 44 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 28378787 Common csd2 cysteine desulfurase lp_2180 237 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 28379444 Nonpathogen - integral membrane protein lp_3016 3 None None None 28377500 Common - prophage Lp1 protein 2 lp_0625 4 None None None 28378490 Common gshR3 glutathione reductase lp_1822 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 28379965 Common pdc p-coumaric acid decarboxylase lp_3665 11 COG3479 COG3479, Phenolic acid decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 28379577 Common rrp11 response regulator lp_3191 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 28377981 Nonpathogen - hypothetical protein lp_1207 1 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 28379974 Common - cell surface protein precursor lp_3678 8 None None None 28379839 Common pbg9 6-phospho-beta-glucosidase lp_3525 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 28379313 Common - transcription regulator lp_2842 181 COG0583 LysR, Transcriptional regulator Transcription 28379078 Common metA homoserine O-succinyltransferase lp_2537 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 28379354 Common - ABC transporter, ATP-binding and permease protein lp_2894 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 28379779 Nonpathogen - hypothetical protein lp_3459 2 None None None 28379742 Common - integral membrane protein (putative) lp_3410 3 None None None 28379868 Common araR arabinose operon repressor lp_3558 134 COG1609 PurR, Transcriptional regulators Transcription 28378159 Common ribA GTP cyclohydrolase II lp_1437 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 28378730 Common cps4A exopolysaccharide biosynthesis protein lp_2108 19 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 28377303 Common - transport protein lp_0394 21 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377694 Common pox2 pyruvate oxidase lp_0852 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 28377576 Common galE1 UDP-glucose 4-epimerase lp_0709 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 28377667 Common - integral membrane protein lp_0817 19 COG4330 COG4330, Predicted membrane protein Function unknown 28377322 Common plnD response regulator PlnD, repressor lp_0418 12 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 28378719 Common pts16ABC fructose PTS, EIIABC lp_2097 138 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 28379601 Common - transcription regulator lp_3221 128 COG1609 PurR, Transcriptional regulators Transcription 28379106 Nonpathogen - hypothetical protein lp_2573 1 None None None 28379662 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase lp_3298 200 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 28377353 Common - hypothetical protein lp_0452 34 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 28379226 Common lplA2 lipoate-protein ligase lp_2734 74 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 28377710 Common gph1 phosphoglycolate phosphatase (putative) lp_0872 179 COG0546 Gph, Predicted phosphatases General function prediction only 28377559 Common - integral membrane protein (putative) lp_0690 59 COG2898 COG2898, Uncharacterized conserved protein Function unknown 28379918 Common - hypothetical protein lp_3613 20 COG4702 COG4702, Uncharacterized conserved protein Function unknown 28377103 Common - transcription regulator (putative) lp_0162 28 COG1309 AcrR, Transcriptional regulator Transcription 28378670 Common aroF chorismate synthase lp_2037 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 28378390 Common - hypothetical protein lp_1701 103 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 28377032 Common - 4-hydroxyphenylacetate-3-hydroxylase lp_0070 50 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 28377224 Common - membrane-bound protease, CAAX family lp_0301 9 None None None 28377218 Common - transport protein lp_0295 103 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 28379536 Common - stress induced DNA binding protein lp_3128 126 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 28379162 Common pts19B N-acetylgalactosamine-specific PTS system transporter subunit IIB lp_2650 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 28379889 Common agrC histidine protein kinase; sensor protein lp_3581 11 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 28377482 Common dut trimetaphosphatase lp_0604 51 COG0756 Dut, dUTPase Nucleotide transport and metabolism 28377750 Common - transport protein lp_0922 213 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28379880 Common - N-acetylmannosamine-6-phosphate 2-epimerase lp_3571 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 28378521 Common - hypothetical protein lp_1866 11 COG4698 COG4698, Uncharacterized protein conserved in bacteria Function unknown 28378818 Common cutC copper homeostasis protein lp_2220 56 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 28378276 Common - integral membrane protein lp_1571 113 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 28379504 Common - hypothetical protein lp_3091 32 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28378108 Nonpathogen - lipoprotein precursor (putative) lp_1369 1 None None None 28378218 Nonpathogen - hypothetical protein lp_1503 2 None None None 28378135 Common - cell surface protein, ErfK family lp_1403 15 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 28379616 Common - oxidoreductase lp_3239 65 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28377990 Common glf2 UDP-galactopyranose mutase lp_1219 55 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 28378557 Common - integral membrane protein lp_1908 4 None None None 28378002 Common - priming glycosyltransferase lp_1233 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 28379177 Common hsp2 small heat shock protein lp_2668 110 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 28378065 Common - phosphatase (putative) lp_1315 83 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 28378762 Common suhB myo-inositol-1(or 4)-monophosphatase lp_2147 189 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 28379007 Nonpathogen - prophage Lp2 protein 13 lp_2444 1 None None None 28379134 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase lp_2610 219 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 28377283 Common choQ glycine betaine/carnitine/choline ABC transporter, ATP-binding protein lp_0368 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 28379755 Common - hypothetical protein lp_3425 7 None None None 28379959 Common rbsD ribose transport protein, membrane-associated protein lp_3659 44 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 28377997 Common cps3J polysaccharide biosynthesis protein lp_1227 14 None None None 28379555 Nonpathogen - hypothetical protein lp_3161 3 None None None 28377672 Common - protein containing diguanylate cyclase/phosphodiesterase domain 2 (EAL) lp_0823 86 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 28378094 Common - transcription regulator (putative) lp_1352 82 COG1733 COG1733, Predicted transcriptional regulators Transcription 28378881 Common - integral membrane protein lp_2290 9 COG4485 COG4485, Predicted membrane protein Function unknown 28377408 Common acpS holo-[acyl-carrier protein] synthase lp_0522 133 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 28379155 Nonpathogen - hypothetical protein lp_2641 2 None None None 28378377 Common - transcription regulator (putative) lp_1688 14 COG1309 AcrR, Transcriptional regulator Transcription 28378565 Common - integral membrane protein lp_1916 4 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 28377433 Common - transcription regulator lp_0549 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 28377874 Nonpathogen - hypothetical protein lp_1081 1 None None None 28379895 Common - transcription regulator (putative) lp_3588 57 COG1959 COG1959, Predicted transcriptional regulator Transcription 28379927 Common srlD1 sorbitol-6-phosphate 2-dehydrogenase lp_3623 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 28379557 Common - transposase, fragment lp_3165 17 None None None 28378966 Common - prophage Lp2 protein 56, lysin lp_2401 9 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 28379250 Common - ADP-ribose pyrophosphatase lp_2762 170 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 28377229 Common - hypothetical protein lp_0307 5 None None None 28378307 Common opuA glycine betaine/carnitine/choline ABC transporter, ATP-binding protein lp_1607 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 28378843 Nonpathogen - hypothetical protein lp_2246 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 28377160 Common pts2CB mannitol PTS, EIICB lp_0230 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 28379977 Common trmE tRNA modification GTPase TrmE lp_3682 225 COG0486 ThdF, Predicted GTPase General function prediction only 28379951 Common - regulator lp_3650 11 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 28379634 Common - cell surface hydrolase, membrane-bound (putative) lp_3265 64 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 28379170 Common - transcription regulator lp_2661 113 COG2188 PhnF, Transcriptional regulators Transcription 28379737 Common - integral membrane protein lp_3405 22 COG3610 COG3610, Uncharacterized conserved protein Function unknown 28377569 Nonpathogen - hypothetical protein lp_0701 2 None None None 28377167 Nonpathogen - hypothetical protein lp_0239 2 None None None 28378662 Common hrcA heat-inducible transcription repressor lp_2029 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 28378909 Common ezrA septation ring formation regulator EzrA lp_2328 37 COG4477 EzrA, Negative regulator of septation ring formation Cell division and chromosome partitioning 28377153 Common gpo glutathione peroxidase lp_0220 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 28378805 Common mraW cell division protein MraW lp_2202 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 28378676 Common nusA transcription elongation factor NusA lp_2043 218 COG0195 NusA, Transcription elongation factor Transcription 28377033 Nonpathogen - hypothetical protein lp_0071 1 None None None 28377159 Common pepD1 dipeptidase lp_0228 23 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 28377318 Nonpathogen plnQ plantaricin biosynthesis protein PlnQ lp_0413 1 None None None 28378669 Nonpathogen - hypothetical protein lp_2036 3 None None None 28378282 Common glpQ2 glycerophosphodiester phosphodiesterase lp_1578 179 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 28377057 Common - hypothetical protein lp_0104 27 COG3875 COG3875, Uncharacterized conserved protein Function unknown 28379842 Common bglG5 transcription antiterminator lp_3529 29 COG3711 BglG, Transcriptional antiterminator Transcription 28377079 Common - hypothetical protein lp_0131 5 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 28379749 Common - transcription regulator (putative) lp_3417 13 COG1309 AcrR, Transcriptional regulator Transcription 28378079 Common - integral membrane protein lp_1332 58 COG1511 COG1511, Predicted membrane protein Function unknown 28377535 Common - prophage Lp1 protein 40 lp_0663 5 None None None 28378429 Common - ABC transporter, substrate binding protein lp_1749 125 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 28379835 Common - transcription regulator lp_3521 84 COG1737 RpiR, Transcriptional regulators Transcription 28378414 Common mvaK2 phosphomevalonate kinase lp_1733 19 COG1577 ERG12, Mevalonate kinase Lipid metabolism 28378501 Common parE DNA topoisomerase IV subunit B lp_1840 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 28379283 Nonpathogen - transcription regulator (putative) lp_2800 4 COG1846 MarR, Transcriptional regulators Transcription 28378946 Common upp uracil phosphoribosyltransferase lp_2374 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 28377683 Nonpathogen - integral membrane protein lp_0838 1 None None None 28379081 Common - ABC transporter, permease protein (putative) lp_2542 48 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 28377205 Common - transcription regulator lp_0281 58 COG0789 SoxR, Predicted transcriptional regulators Transcription 28379807 Common - fumarate reductase, flavoprotein subunit precursor lp_3491 118 COG0431 COG0431, Predicted flavoprotein General function prediction only 28377376 Common - transcription regulator lp_0482 8 COG1476 COG1476, Predicted transcriptional regulators Transcription 28379187 Common - aminotransferase with N-terminal regulator domain lp_2683 173 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 28378056 Nonpathogen - integral membrane protein lp_1300 3 None None None 28379264 Common pbg5 6-phospho-beta-glucosidase lp_2778 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 28377705 Nonpathogen - hypothetical protein lp_0865 2 None None None 28378965 Nonpathogen - prophage Lp2 protein 57 lp_2400 1 None None None 28379739 Common uppP undecaprenyl pyrophosphate phosphatase lp_3407 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 28377268 Nonpathogen - integral membrane protein lp_0351 1 None None None 28378683 Common frr ribosome recycling factor lp_2052 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 28377625 Common aad D-alanyl-D-alanine dipeptidase lp_0769 51 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 28377933 Common - cell surface hydrolase (putative) lp_1156 10 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 28378009 Common recX recombination regulator RecX lp_1240 53 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 28379878 Common - transposase (putative) lp_3569 63 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 28378406 Common - amino acid transport protein lp_1722 131 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 28378973 Common - prophage Lp2 protein 49 lp_2408 4 None None None 28377638 Common serA2 phosphoglycerate dehydrogenase lp_0785 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 28377400 Common rpmE ribosomal protein L31 lp_0512 145 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 28378476 Common - hypothetical protein lp_1806 4 None None None 28379528 Common - cell surface protein (putative) lp_3117 26 COG3889 COG3889, Predicted solute binding protein General function prediction only 28378487 Common tagB2 teichoic acid biosynthesis protein lp_1819 33 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 28377262 Common tagH teichoic acid ABC transporter, ATP-binding protein lp_0344 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 28379128 Common - hydrolase, HAD superfamily, Cof family lp_2601 99 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28377749 Common - transcription regulator (putative) lp_0921 121 COG1733 COG1733, Predicted transcriptional regulators Transcription 28379521 Common - oxidoreductase (putative) lp_3108 36 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28377858 Common rpoA DNA-directed RNA polymerase subunit alpha lp_1062 219 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 28378248 Common rpmF 50S ribosomal protein L32 lp_1535a 52 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 28378927 Common - amino acid ABC transporter, substrate binding protein lp_2350 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 28377851 Common rplO ribosomal protein L15 lp_1055 175 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 28378664 Common ribC2 bifunctional protein: riboflavin kinase; FMN adenylyltransferase lp_2031 210 COG0196 RibF, FAD synthase Coenzyme metabolism 28377417 Common argD acetylornithine aminotransferase lp_0531 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 28379523 Common - short-chain dehydrogenase/oxidoreductase lp_3112 138 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 28378004 Nonpathogen - hypothetical protein lp_1235 2 None None None 28377474 Common - transcription regulator lp_0593 63 COG1316 LytR, Transcriptional regulator Transcription 28379947 Common - transcription regulator lp_3646 144 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 28379088 Common hisE phosphoribosyl-ATP pyrophosphatase lp_2552 194 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 28377269 Common zmp1 extracellular zinc metalloproteinase (putative) lp_0353 2 COG5549 COG5549, Predicted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 28378852 Common pepQ Xaa-Pro dipeptidase lp_2258 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 28377009 Common htrA serine protease HtrA lp_0043 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 28377386 Common deoR deoxyribonucleoside regulator lp_0495 68 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 28377648 Common secG preprotein translocase subunit SecG lp_0795 5 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 28378100 Nonpathogen - extracellular protein, membrane-anchored (putative) lp_1357 1 None None None 28378612 Common - hypothetical protein lp_1969 198 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 28378736 Common - hypothetical protein lp_2114 15 COG1694 MazG, Predicted pyrophosphatase General function prediction only 28379119 Common - purine nucleosidase lp_2591 87 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 28377596 Common comFA ATP-dependent DNA helicase/translocase (putative) lp_0735 38 COG4098 comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) DNA replication, recombination, and repair 28378522 Common - hypothetical protein lp_1867 12 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 28378890 Common - hypothetical protein lp_2304 62 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 28377126 Common sacA beta-fructofuranosidase lp_0187 52 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 28379754 Nonpathogen - hypothetical protein lp_3423 1 None None None 28377293 Nonpathogen - hypothetical protein lp_0379 1 None None None 28378659 Common dnaJ chaperone protein DnaJ lp_2026 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 28379481 Common - extracellular protein lp_3064 46 None None None 28379180 Common nrdI hypothetical protein lp_2673 22 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 28377840 Common rpmC 50S ribosomal protein L29 lp_1043 151 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 28379141 Common - cell surface hydrolase, membrane-bound (putative) lp_2620 72 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 28379799 Common lacL beta-galactosidase, large subunit lp_3483 69 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 28379335 Common pgm8 phosphoglycerate mutase (putative) lp_2868 33 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 28378147 Nonpathogen - hypothetical protein lp_1419 1 None None None 28378895 Common glnQ4 glutamine ABC transporter, ATP-binding protein lp_2313 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 28378128 Common - transcription regulator levR (putative) lp_1396 14 COG3933 COG3933, Transcriptional antiterminator Transcription 28378121 Nonpathogen - hypothetical protein lp_1388 3 None None None 28378870 Nonpathogen - hypothetical protein lp_2276 1 None None None 28378202 Nonpathogen - hypothetical protein lp_1486 1 None None None 28379678 Common - hypothetical protein lp_3323 5 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 28378657 Common - transposase, fragment lp_2022 5 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 28379603 Common - integral membrane protein lp_3223 39 COG1434 COG1434, Uncharacterized conserved protein Function unknown 28379790 Common ram2 alpha-L-rhamnosidase (putative) lp_3473 9 None None None 28379402 Common - transcription regulator (putative) lp_2963 10 COG1309 AcrR, Transcriptional regulator Transcription 28377645 Common enoA1 phosphopyruvate hydratase lp_0792 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 28379781 Common - hypothetical protein lp_3461 27 COG3899 COG3899, Predicted ATPase General function prediction only 28378072 Common - sugar ABC transporter, ATP-binding protein (putative) lp_1324 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 28379142 Common pepF2 oligoendopeptidase F lp_2621 88 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 28377769 Common - cell surface protein precursor, GY family lp_0946 14 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 28377938 Common - oxidoreductase (putative) lp_1161 114 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 28379625 Nonpathogen - hypothetical protein lp_3250 2 None None None 28378740 Common tuf elongation factor Tu lp_2119 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 28378829 Nonpathogen - hypothetical protein lp_2231a 1 None None None 28379426 Common - hypothetical protein lp_2993 34 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 28377097 Nonpathogen - hypothetical protein lp_0155 1 None None None 28379562 Common xylR xylose operon regulator lp_3172 93 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 28378527 Common - hypothetical protein lp_1872 2 None None None 28379391 Common ubiD 3-octaprenyl-4-hydroxybenzoate carboxy-lyase lp_2945 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 28379633 Common crtM phytoene synthase lp_3263 99 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 28379478 Common - transcription regulator lp_3060 46 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 28377341 Common pts8C cellobiose PTS, EIIC lp_0439 39 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 28378918 Nonpathogen - integral membrane protein lp_2339 1 None None None 28378570 Common - transcription regulator (putative) lp_1922 10 COG1846 MarR, Transcriptional regulators Transcription 28378179 Common - hypothetical protein lp_1460 177 COG0073 ARC1, EMAP domain General function prediction only 28377399 Common rho transcription termination factor Rho lp_0511 202 COG1158 Rho, Transcription termination factor Transcription 28377347 Common - hypothetical protein lp_0445 6 None None None 28377257 Common birA1 biotin--[acetyl-CoA-carboxylase] ligase and biotin operon repressor lp_0337 204 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 28378630 Common - hypothetical protein lp_1989 129 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 28377998 Nonpathogen - hypothetical protein lp_1228 2 None None None 28378031 Common oppF oligopeptide ABC transporter, ATP-binding protein lp_1265 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 28377197 Nonpathogen - hypothetical protein lp_0272 4 None None None 28378643 Common ISP2 transposase lp_2006 23 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 28378354 Common - integral membrane protein lp_1663 7 None None None 28378920 Common bla2 beta-lactamase (putative) lp_2341 47 COG2367 PenP, Beta-lactamase class A Defense mechanisms 28379214 Common purH bifunctional protein: phosphoribosylaminoimidazolecarboxamide formyltransferase; IMP cyclohydrolase lp_2720 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 28377940 Common - nucleotide-binding protein, universal stress protein UspA family lp_1163 86 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 28378536 Common cmk cytidylate kinase lp_1883 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 28378433 Common - hypothetical protein lp_1753 11 COG4474 COG4474, Uncharacterized protein conserved in bacteria Function unknown 28378172 Nonpathogen - hypothetical protein lp_1453 1 None None None 28379449 Common - protein containing diguanylate cyclase/phosphodiesterase domain 1 (GGDEF) lp_3021 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 28378560 Common - transcription regulator (putative) lp_1911 14 COG1846 MarR, Transcriptional regulators Transcription 28378295 Common rpmA 50S ribosomal protein L27 lp_1594 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 28376992 Common glgB glycogen branching enzyme lp_0020 143 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 28378597 Common - ABC transporter, ATP-binding protein lp_1954 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28377246 Common - transcription regulator lp_0325 114 COG1725 COG1725, Predicted transcriptional regulators Transcription 28378369 Common accD2 acetyl-CoA carboxylase, carboxyl transferase subunit beta lp_1679 195 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 28378580 Common thgA2 galactoside O-acetyltransferase lp_1933 94 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 28377565 Common - cytosine/adenosine deaminase lp_0696 214 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 28379344 Common - hydrolase, HAD superfamily lp_2879 76 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 28377627 Common - HD superfamily hydrolase (putative) lp_0771 30 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 28377021 Nonpathogen - hypothetical protein lp_0058 5 None None None 28378232 Nonpathogen - hypothetical protein lp_1518 2 None None None 28379045 Nonpathogen - hypothetical protein lp_2493 1 None None None 28378713 Common - short-chain dehydrogenase/oxidoreductase lp_2089 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 28377331 Common plnV integral membrane protein plnV, membrane-bound protease CAAX family lp_0428 6 None None None 28377355 Common - transport protein lp_0455 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377392 Common serS1 seryl-tRNA synthetase lp_0501 245 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 28377608 Common pstB phosphate ABC transporter, ATP-binding protein lp_0749 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 28379442 Common - extracellular protein lp_3014 10 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 28378342 Common - ABC transporter, ATP-binding protein lp_1648 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28379944 Common - sugar ABC transporter, permease protein lp_3643 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 28377428 Common - hypothetical protein lp_0543 222 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 28376977 Common - hypothetical protein lp_0004 30 COG2501 COG2501, Uncharacterized conserved protein Function unknown 28378310 Common opuD glycine betaine/carnitine/choline ABC transporter, ATP-binding protein lp_1610 191 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 28377002 Common cspL cold shock protein CspL lp_0031 183 COG1278 CspC, Cold shock proteins Transcription 28377650 Common - ribonuclease R lp_0797 193 COG0557 VacB, Exoribonuclease R Transcription 28377068 Common - NTP pyrophosphohydrolase lp_0119 57 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 28378989 Common - prophage Lp2 protein 33 lp_2424 8 None None None 28378225 Common - hypothetical protein lp_1511 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 28377151 Common - ABC transporter, ATP-binding protein lp_0218 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 28379467 Common zmp4 extracellular zinc metalloproteinase lp_3043 2 COG5549 COG5549, Predicted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 28378167 Nonpathogen - cell surface protein precursor lp_1447 1 None None None 28378810 Common cspR rRNA methyltransferase lp_2211 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 28377558 Nonpathogen - prophage Lp1 protein 66, lipoprotein precursor lp_0689 2 None None None 28377955 Common cps1E acyltransferase/acetyltransferase lp_1181 26 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 28379800 Common lacM beta-galactosidase, small subunit lp_3484 36 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 28377468 Common pts10B mannose PTS, EIIB lp_0587 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 28377784 Common rluE pseudouridylate synthase lp_0963 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 28377972 Common cps2B exopolysaccharide biosynthesis protein; chain length determinator Wzz lp_1198 177 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 28377715 Common glnM glutamine ABC transporter, permease protein lp_0882 183 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 28377250 Common fba fructose-bisphosphate aldolase lp_0330 177 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 28378796 Common - cell division protein (putative) lp_2192 54 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 28377572 Common holB DNA polymerase III subunit delta' lp_0705 216 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 28379515 Common - transcription regulator lp_3102 17 COG1309 AcrR, Transcriptional regulator Transcription 28377618 Common nox1 NADH oxidase lp_0760 240 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 28377104 Common - hypothetical protein lp_0163 148 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 28378207 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein MobA (putative) lp_1491 7 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 28377613 Common hprK HPr kinase/phosphorylase lp_0754 79 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 28377411 Common kup1 potassium uptake protein lp_0525 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 28377447 Common nadC1 nicotinate phosphoribosyltransferase lp_0565 122 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 28377065 Common - purine-cytosine transport protein lp_0116 54 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 28378387 Common - hypothetical protein lp_1698 14 COG1359 COG1359, Uncharacterized conserved protein Function unknown 28377542 Nonpathogen - prophage Lp1 protein 47 lp_0670 1 None None None 28378380 Common - integral membrane protein lp_1692 3 None None None 28379721 Nonpathogen - prophage Lp4 protein 6 lp_3384 1 None None None 28377461 Common - HD superfamily hydrolase lp_0580 33 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 28377549 Nonpathogen - prophage Lp1 protein 54 lp_0677 2 None None None 28377551 Nonpathogen - prophage Lp1 protein 56 lp_0679 1 None None None 28378440 Common - glycosyltransferase lp_1763 105 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 28379725 Common - prophage Lp4 protein 2, CI-like repressor lp_3389 2 COG1396 HipB, Predicted transcriptional regulators Transcription 28377536 Common - prophage Lp1 protein 41 lp_0664 6 None None None 28377185 Common - integral membrane protein lp_0259 12 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 28377964 Common rfbD dTDP-4-dehydrorhamnose reductase lp_1190 181 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 28379038 Common - prophage Lp3 protein 1, integrase lp_2480 139 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 28378859 Common - hypothetical protein lp_2265 13 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 28378980 Nonpathogen - prophage Lp2 protein 42 lp_2415 1 None None None 28378959 Nonpathogen - lipoprotein precursor lp_2393 1 None None None 28379883 Nonpathogen - hypothetical protein lp_3574 1 None None None 28378887 Common recA recombinase A lp_2301 242 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 28378867 Common - hypothetical protein lp_2273 16 COG3906 COG3906, Uncharacterized protein conserved in bacteria Function unknown 28377190 Common pts4ABC beta-glucosides PTS, EIIABC lp_0264 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28378911 Common rpsD 30S ribosomal protein S4 lp_2331 248 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 28377859 Common rplQ ribosomal protein L17 lp_1063 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 28378544 Common - hypothetical protein lp_1891 6 None None None 28379193 Common - acetyltransferase (putative) lp_2691 14 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 28377849 Common rpsE 30S ribosomal protein S5 lp_1053 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 28377584 Common rimI1 ribosomal-protein-alanine N-acetyltransferase lp_0718 169 COG0456 RimI, Acetyltransferases General function prediction only 28378319 Common pkn1 serine/threonine protein kinase (putative) lp_1619 157 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 28378210 Common moeA molybdopterin biosynthesis protein MoeA lp_1494 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 28377092 Common - ABC transporter, ATP-binding protein lp_0149 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 28377516 Common - prophage Lp1 protein 20 lp_0643 7 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 28377106 Common - transcription regulator (putative) lp_0165 7 COG1309 AcrR, Transcriptional regulator Transcription 28378620 Common - integral membrane protein lp_1978 81 COG1284 COG1284, Uncharacterized conserved protein Function unknown 28377879 Common aroB 3-dehydroquinate synthase lp_1086 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 28377872 Common rpsI 30S ribosomal protein S9 lp_1078 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 28379240 Nonpathogen - hypothetical protein lp_2749 1 None None None 28377484 Common - ATPase of the PilT family lp_0607 46 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 28379047 Common tagE4 poly(glycerol-phosphate) alpha-glucosyltransferase lp_2498 169 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28379459 Common - hypothetical protein lp_3031 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 28379290 Common - lysin lp_2810 7 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 28377402 Common srtA sortase lp_0514 15 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 28379812 Common ISP2 transposase lp_3496 25 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 28377371 Common - hydrolase (putative) lp_0476 87 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 28378281 Common - hypothetical protein lp_1577 5 None None None 28379953 Common pts38BC sorbitol PTS, EIIBC lp_3653 22 COG3732 SrlE, Phosphotransferase system sorbitol-specific component IIBC Carbohydrate transport and metabolism 28378132 Common pts15C beta-glucosides PTS, EIIC lp_1400 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 28377893 Common mae malic enzyme, NAD-dependent lp_1105 202 COG0281 SfcA, Malic enzyme Energy production and conversion 28379687 Common nha2 Na(+)/H(+) antiporter lp_3338 58 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 28377775 Common - fumarate reductase, flavoprotein subunit precursor lp_0952 62 COG3976 COG3976, Uncharacterized protein conserved in bacteria Function unknown 28377670 Common glmM phosphoglucosamine mutase lp_0820 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 28379235 Common - ABC transporter, ATP-binding protein lp_2743 248 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28377281 Nonpathogen - hypothetical protein lp_0366 2 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 28377089 Nonpathogen - hypothetical protein lp_0145 1 None None None 28379888 Common agrA response regulator; accesory gene regulator protein A lp_3580 46 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 28377567 Common - hypothetical protein lp_0699 123 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 28378702 Common - nitrate ABC transporter, ATP-binding protein lp_2076 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 28377601 Common prfB peptide chain release factor 2 lp_0741 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 28377171 Common - oxidoreductase (putative) lp_0244 104 COG0431 COG0431, Predicted flavoprotein General function prediction only 28379832 Common pts31BC putative PTS transporter components IIBC lp_3518 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 28379333 Nonpathogen - integral membrane protein (putative) lp_2866 1 None None None 28378845 Common comGB ComG operon protein 2 lp_2248 12 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 28378453 Common fhs formate--tetrahydrofolate ligase lp_1779 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 28379209 Common - protein containing diguanylate cyclase/phosphodiesterase domain 2 (EAL) lp_2714 8 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 28377481 Common - acetyltransferase (putative) lp_0603 31 COG2388 COG2388, Predicted acetyltransferase General function prediction only 28378559 Common drrA ABC transporter, ATP-binding protein lp_1910 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28379819 Common - transport protein lp_3503 16 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 28379745 Common - cell surface protein precursor lp_3413 7 None None None 28379205 Common pucR purine transport regulator lp_2708 27 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 28377214 Common - oxidoreductase lp_0291 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 28379104 Common asd2 aspartate-semialdehyde dehydrogenase lp_2570 235 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 28377458 Common pts9D mannose PTS, EIID lp_0577 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 28378156 Common - integral membrane protein lp_1431 4 None None None 28378096 Nonpathogen - hypothetical protein lp_1354 1 None None None 28379763 Common cadA cadmium transporting P-type ATPase lp_3435 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 28378288 Common - hypothetical protein lp_1585 7 COG4508 COG4508, Uncharacterized protein conserved in bacteria Function unknown 28377970 Common - integrase/recombinase, fragment (putative) lp_1196 80 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 28379000 Nonpathogen - prophage Lp2 protein 22 lp_2435 1 None None None 28378305 Common argR2 arginine catabolic regulator lp_1604 58 COG1438 ArgR, Arginine repressor Transcription 28379575 Common dacA1 serine-type D-Ala-D-Ala carboxypeptidase lp_3189 144 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 28377434 Common lysS lysyl-tRNA synthetase lp_0550 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 28378196 Common moaA molybdenum cofactor biosynthesis protein A lp_1480 207 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 28378087 Common - transport protein lp_1343 48 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 28379137 Common - ABC transporter, ATP-binding protein lp_2614 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 28377076 Common - transcription regulator (putative) lp_0128 3 COG1846 MarR, Transcriptional regulators Transcription 28378042 Common - hypothetical protein lp_1281 7 COG4703 COG4703, Uncharacterized protein conserved in bacteria Function unknown 28377255 Nonpathogen - hypothetical protein lp_0335 2 None None None 28377138 Common serA1 phosphoglycerate dehydrogenase lp_0203 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 28378679 Common proS prolyl-tRNA synthetase lp_2048 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28378963 Common - prophage Lp2 protein 59; xylanase/chitin deacetylase (putative) lp_2397 73 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 28377451 Common tex transcription accessory protein lp_0569 202 COG2183 Tex, Transcriptional accessory protein Transcription 28377991 Nonpathogen cps3D polysaccharide biosynthesis protein (putative) lp_1220 1 None None None 28379223 Common purE phosphoribosylaminoimidazole carboxylase, catalytic subunit lp_2729 230 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 28379639 Common purA adenylosuccinate synthase lp_3270 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 28378255 Common hpk5 histidine protein kinase; sensor protein lp_1545 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 28379018 Common - prophage Lp2 protein 2, integrase lp_2455 53 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 28378629 Nonpathogen - integral membrane protein lp_1988 1 None None None 28377164 Nonpathogen - hypothetical protein lp_0235 1 None None None 28379893 Common lox lactate oxidase lp_3586 114 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 28377204 Common - transport protein lp_0280 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28379613 Common - hypothetical protein lp_3236 67 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28378293 Common rplU ribosomal protein L21 lp_1592 214 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 28379387 Nonpathogen - hypothetical protein lp_2939 1 None None None 28377589 Common - membrane-bound protease, CAAX family lp_0726 22 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 28377288 Common - cell surface protein precursor (putative) lp_0373 4 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 28377697 Common - acyltransferase (putative) lp_0856 100 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 28377570 Common tmk thymidylate kinase lp_0703 229 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 28379099 Common - Mg2+ and Co2+ transport protein lp_2565 33 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 28378060 Common - hypothetical protein lp_1310 8 None None None 28378061 Common tagE2 poly(glycerol-phosphate) alpha-glucosyltransferase lp_1311 92 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28379534 Common - fumarate reductase, flavoprotein subunit precursor, N-terminally truncated lp_3125 73 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 28379458 Common - hypothetical protein lp_3030 28 COG1881 COG1881, Phospholipid-binding protein General function prediction only 28378772 Common - transcription regulator lp_2159 102 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 28377921 Common purK2 phosphoribosylaminoimidazole carboxylase, ATPase subunit lp_1141 195 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 28377158 Common gnp glucosamine-6-phosphate isomerase lp_0226 89 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 28377129 Common - oxidoreductase lp_0190 170 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 28377824 Common - transcription regulator (putative) lp_1020 116 COG1309 AcrR, Transcriptional regulator Transcription 28378906 Common gshA glutamate--cysteine ligase (putative) lp_2324 58 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 28379178 Nonpathogen - hypothetical protein lp_2669 1 None None None 28378671 Common - transport protein lp_2038 14 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 28378341 Common - hypothetical protein lp_1645 13 None None None 28379648 Common - hypothetical protein lp_3283 61 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 28379972 Common - extracellular protein lp_3676 3 None None None 28378022 Nonpathogen - extracellular protein lp_1256 1 None None None 28378875 Common - preprotein translocase, subunit (putative) lp_2281 35 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 28378049 Common - acetyltransferase (putative) lp_1292 17 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 28379439 Common pbg6 6-phospho-beta-glucosidase lp_3011 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 28377124 Common sacK1 fructokinase lp_0184 128 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 28379699 Common hsp3 small heat shock protein lp_3352 151 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 28379005 Nonpathogen - prophage Lp2 protein 16 lp_2441 2 None None None 28379545 Common pts25B PTS, EIIB lp_3137 23 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 28377502 Common - prophage Lp1 protein 5 lp_0628 10 None None None 28379320 Common - ABC transporter, permease protein (putative) lp_2850 23 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 28379200 Common carB carbamoyl phosphate synthase large subunit lp_2700 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 28379494 Common - hydrolase, HAD superfamily lp_3078 173 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 28378608 Common glyQ glycyl-tRNA synthetase subunit alpha lp_1965 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 28377655 Common - hypothetical protein lp_0804 6 COG4894 COG4894, Uncharacterized conserved protein Function unknown 28379759 Common - iron dependent peroxidase (putative) lp_3430 49 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 28379506 Common - muramidase (putative) lp_3093 9 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 28378271 Common - hypothetical protein lp_1565 7 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 28378465 Common - ABC transporter, permease protein lp_1792 3 None None None 28379322 Common - 4-carboxymuconolactone decarboxylase (putative) lp_2852 71 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 28379064 Common - extracellular protein, gamma-D-glutamate-meso-diaminopimelate muropeptidase (putative) lp_2520 151 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 28378728 Common cps4C exopolysaccharide biosynthesis protein lp_2106 40 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 28377494 Common - cell surface hydrolase, membrane-bound (putative) lp_0618 10 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 28378954 Common pmi mannose-6-phosphate isomerase lp_2384 51 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 28379092 Common hisH imidazole glycerol phosphate synthase subunit HisH lp_2557 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 28377758 Common asp2 alkaline shock protein lp_0930 3 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 28377757 Common asp1 alkaline shock protein lp_0929 37 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 28378803 Common pbp2B2 penicillin binding protein 2B lp_2200 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 28377986 Common - hypothetical protein lp_1213 4 None None None 28379706 Common bsh3 choloylglycine hydrolase lp_3362 46 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 28377725 Common - multidrug transport protein lp_0893 108 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28377764 Common hsdR type I site-specific deoxyribonuclease, HsdR subunit lp_0938 140 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 28377144 Common ack1 acetate kinase lp_0210 161 COG0282 ackA, Acetate kinase Energy production and conversion 28378037 Common - glycosyltransferase lp_1275 220 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28377113 Common - transcription regulator lp_0173 126 COG1609 PurR, Transcriptional regulators Transcription 28378399 Common xylH 4-oxalocrotonate tautomerase lp_1712 26 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 28377219 Common tag1 DNA-3-methyladenine glycosylase I lp_0296 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 28377631 Common argG argininosuccinate synthase lp_0775 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 28378355 Common - aminohydrolase lp_1664 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 28379640 Common guaC guanosine 5'-monophosphate oxidoreductase lp_3271 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 28378549 Common pfkA 6-phosphofructokinase lp_1898 155 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 28379417 Common livD branched-chain amino acid ABC transporter, ATP-binding protein lp_2982 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 28378516 Common - hypothetical protein lp_1859 42 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 28379907 Common pts36B galactitol PTS, EIIB lp_3600 3 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 28378724 Common cps4G glycosyltransferase lp_2102 97 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28378181 Common murC UDP-N-acetylmuramate--L-alanine ligase lp_1462 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 28379315 Common tagE6 poly(glycerol-phosphate) alpha-glucosyltransferase lp_2844 183 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28379858 Common pts35B galactitol PTS, EIIB lp_3547 18 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 28378759 Nonpathogen - integral membrane protein lp_2143 4 None None None 28377165 Common trxA1 thioredoxin lp_0236 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 28379682 Common ISP2-N transposase, N-terminal fragment lp_3331 19 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 28377801 Common - lipoprotein precursor lp_0988 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 28377808 Common - metal-dependent regulator lp_0996 104 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 28379432 Nonpathogen - integral membrane protein lp_3002 1 None None None 28379581 Common - translation-associated GTPase lp_3196 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 28379058 Common - integral membrane protein lp_2512 4 COG4720 COG4720, Predicted membrane protein Function unknown 28378312 Common gmk1 guanylate kinase lp_1612 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 28379377 Nonpathogen - hypothetical protein lp_2926 1 COG4892 COG4892, Predicted heme/steroid binding protein General function prediction only 28378080 Nonpathogen - hypothetical protein lp_1333 2 None None None 28379851 Common ulaA ascorbate-specific PTS system enzyme IIC lp_3540 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 28378266 Common pheT phenylalanyl-tRNA synthetase subunit beta lp_1559 248 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 28378408 Common - rRNA methylase (putative) lp_1724 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 28377196 Common vdcB 3-octaprenyl-4-hydroxybenzoate carboxy-lyase lp_0271 154 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 28378785 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase lp_2178 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 28377184 Nonpathogen - hypothetical protein lp_0258 1 None None None 28379393 Common - hypothetical protein lp_2948 8 COG4640 COG4640, Predicted membrane protein Function unknown 28378013 Nonpathogen - hypothetical protein lp_1244 1 None None None 28379041 Common - transcription regulator (putative) lp_2484 9 COG1846 MarR, Transcriptional regulators Transcription 28379438 Common pts23C cellobiose PTS, EIIC lp_3010 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 28377472 Common accD1 acetyl-CoA carboxylase, carboxyl transferase subunit beta lp_0591 210 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 28377882 Common ttdB L(+)-tartrate dehydratase subunit beta lp_1089 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 28378188 Common nifU NifU-like protein lp_1471 147 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 28379161 Common pts19C N-acetylgalactosamine PTS, EIIC lp_2649 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 28378742 Common - metallo-beta-lactamase superfamily protein (putative) lp_2122 157 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 28378932 Nonpathogen - hypothetical protein lp_2357 2 None None None 28377131 Common agl3 alpha-glucosidase lp_0193 166 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 28378760 Nonpathogen - extracellular protein lp_2145 2 COG3889 COG3889, Predicted solute binding protein General function prediction only 28377665 Common - Na(+)/H(+) antiporter (putative) lp_0815 102 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 28377856 Common rpsM 30S ribosomal protein S13 lp_1060 244 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 28378542 Common - transcription regulator (putative) lp_1889 148 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 28377793 Common - lipase/esterase lp_0973 110 COG0657 Aes, Esterase/lipase Lipid metabolism 28377735 Common - 7,8-dihydro-8-oxoguanine-triphosphatase (putative) lp_0903 24 COG2320 GrpB, Uncharacterized conserved protein Function unknown 28378422 Common dnaD DNA replication protein DnaD lp_1741 19 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 28379274 Common serA3 phosphoglycerate dehydrogenase lp_2790 229 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 28378105 Nonpathogen - hypothetical protein lp_1363 2 None None None 28378568 Common eno phosphopyruvate hydratase lp_1920 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 28377273 Common - hypothetical protein lp_0358 103 COG1881 COG1881, Phospholipid-binding protein General function prediction only 28379363 Nonpathogen - membrane-bound protease, CAAX family lp_2911 6 COG4449 COG4449, Predicted protease of the Abi (CAAX) family General function prediction only 28377952 Common cps1B polysaccharide biosynthesis protein lp_1178 117 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 28377883 Common ttdA tartrate dehydratase subunit alpha lp_1090 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 28378431 Common pbp1A penicillin binding protein 1A lp_1751 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 28377677 Nonpathogen - hypothetical protein lp_0828 1 None None None 28379168 Common xpk1 putative phosphoketolase lp_2659 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 28379114 Common trxB2 thioredoxin reductase (NADPH) lp_2585 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 28377548 Common - prophage Lp1 protein 53 lp_0676 3 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 28378018 Common gntK gluconokinase lp_1250 184 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 28378241 Common - hypothetical protein lp_1529 81 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 28379095 Common hisG ATP phosphoribosyltransferase lp_2560 212 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 28379666 Common - multidrug transport protein (putative) lp_3303 180 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28378899 Common mreD cell shape determining protein MreD lp_2317 13 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 28379864 Common araA L-arabinose isomerase lp_3554 35 COG2160 AraA, L-arabinose isomerase Carbohydrate transport and metabolism 28377811 Common - integral membrane protein lp_0999 15 COG3610 COG3610, Uncharacterized conserved protein Function unknown 28377901 Common - fumarate reductase, flavoprotein subunit precursor, N-terminally truncated lp_1113 224 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 28378638 Common - integral membrane protein lp_2001 3 None None None 28378990 Nonpathogen - prophage Lp2 protein 32 lp_2425 1 None None None 28377298 Nonpathogen - hypothetical protein lp_0385 2 None None None 28377128 Common agl2 alpha-glucosidase lp_0189 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 28377839 Common rplP 50S ribosomal protein L16 lp_1041 220 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 28377914 Common - hypothetical protein lp_1132 3 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 28377594 Common pstF phosphate ABC transporter, substrate binding protein lp_0733 177 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 28378820 Common ppnK inorganic polyphosphate/ATP-NAD kinase lp_2222 232 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 28379404 Common - sugar kinase and transcription regulator lp_2965 140 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 28377426 Common - hypothetical protein lp_0541 47 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 28379342 Common - hypothetical protein lp_2877 51 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 28379428 Common - integral membrane protein lp_2995 4 COG0398 COG0398, Uncharacterized conserved protein Function unknown 28378894 Common glnH2 glutamine ABC transporter, substrate binding protein lp_2312 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 28378025 Common - transport protein lp_1259 42 COG0730 COG0730, Predicted permeases General function prediction only 28379405 Common lmrA multidrug ABC transporter, ATP-binding and permease protein lp_2966 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 28378320 Common - translation factor, GTPase (putative) lp_1620 163 COG1162 COG1162, Predicted GTPases General function prediction only 28377301 Nonpathogen - integral membrane protein lp_0391 1 None None None 28378538 Common recQ2 ATP-dependent DNA helicase RecQ lp_1885 232 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 28379783 Common - protein kinase, ABC1 family lp_3464 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 28378223 Common fpg formamidopyrimidine-DNA glycosylase lp_1509 179 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 28378145 Common - hypothetical protein lp_1417 21 COG4717 COG4717, Uncharacterized conserved protein Function unknown 28378370 Common accA2 acetyl-CoA carboxylase, carboxyl transferase subunit alpha lp_1680 186 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 28378655 Common dltX D-Ala-teichoic acid biosynthesis protein (putative) lp_2020 7 None None None 28379212 Common - hypothetical protein lp_2718 22 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 28379217 Common purF amidophosphoribosyltransferase precursor lp_2723 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 28378999 Nonpathogen - prophage Lp2 protein 23 lp_2434 1 None None None 28377580 Common phnE2 phosphonates ABC transporter, permease protein lp_0713 85 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 28377345 Common - hypothetical protein lp_0443 204 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 28379349 Common - hypothetical protein lp_2887 28 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 28379914 Common iolE inositol catabolism protein IolE lp_3607 72 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 28379623 Common fur ferric uptake regulator lp_3247 207 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 28378738 Common clpX ATP-dependent protease ATP-binding subunit lp_2116 224 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 28379718 Nonpathogen - prophage Lp4 protein 9 lp_3381 1 None None None 28377291 Nonpathogen - integral membrane protein lp_0376 1 None None None 28378327 Common plsX fatty acid/phospholipid synthesis protein lp_1628 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 28378520 Common - hypothetical protein lp_1865 12 COG4479 COG4479, Uncharacterized protein conserved in bacteria Function unknown 28379629 Common lrgB effector of murein hydrolase (putative) lp_3255 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 28377099 Common - hypothetical protein lp_0158 12 None None None 28377862 Common - integral membrane protein lp_1067 12 COG4769 COG4769, Predicted membrane protein Function unknown 28377308 Common napA1 Na(+)/H(+) antiporter lp_0400 209 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 28378552 Nonpathogen - hypothetical protein lp_1901 1 None None None 28379254 Common - hypothetical protein lp_2766 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 28378124 Nonpathogen - hypothetical protein lp_1392 1 None None None 28378451 Common esbB cell wall enzyme lp_1777 7 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 28377070 Nonpathogen - hypothetical protein lp_0121 1 None None None 28377908 Common - integral membrane protein lp_1121 13 COG4684 COG4684, Predicted membrane protein Function unknown 28377325 Nonpathogen plnE bacteriocin precursor peptide PlnE (putative) lp_0422 1 None None None 28377476 Common - transport protein lp_0595 42 COG2510 COG2510, Predicted membrane protein Function unknown 28377669 Common - hypothetical protein lp_0819 12 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 28377118 Common malA maltose/maltodextrin ABC transporter subunit (putatie) lp_0178 4 COG5521 COG5521, Predicted integral membrane protein Function unknown 28377514 Common - prophage Lp1 protein 18 lp_0641 17 COG3723 RecT, Recombinational DNA repair protein (RecE pathway) DNA replication, recombination, and repair 28377977 Common cps2G glycosyltransferase lp_1203 20 None None None 28379898 Common - sugar specific permease (putative) lp_3591 8 COG2364 COG2364, Predicted membrane protein Function unknown 28377636 Common - hypothetical protein lp_0781 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 28378865 Common mutS DNA mismatch repair protein MutS2 lp_2271 200 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 28379189 Common dapA2 dihydrodipicolinate synthase lp_2685 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 28379671 Common pflB2 formate C-acetyltransferase lp_3313 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 28378480 Common - lipoprotein precursor (putative) lp_1812 2 None None None 28377421 Common - hypothetical protein lp_0536 9 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 28377533 Common - prophage Lp1 protein 38 lp_0661 16 COG1783 XtmB, Phage terminase large subunit General function prediction only 28378300 Common folD bifunctional protein: methylenetetrahydrofolate dehydrogenase; methenyltetrahydrofolate cyclohydrolase lp_1599 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 28378074 Common - sugar ABC transporter, permease protein (putative) lp_1326 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 28377629 Common uvrA1 excinuclease ABC, subunit A lp_0773 237 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 28379848 Common - hydrolase, HAD superfamily, Cof family lp_3537 131 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28378619 Common tagB3 teichoic acid biosynthesis protein lp_1977 26 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 28379003 Nonpathogen - prophage Lp2 protein 18 lp_2439 2 None None None 28379731 Nonpathogen - hypothetical protein lp_3396 1 None None None 28377083 Nonpathogen - hypothetical protein lp_0135 1 None None None 28377685 Common ppx2 exopolyphosphatase lp_0841 182 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 28377449 Common pacL2 cation transporting P-type ATPase lp_0567 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 28379148 Nonpathogen - integral membrane protein lp_2630 1 None None None 28378794 Common - cell division protein (putative) lp_2190 32 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 28379150 Common trxH thioredoxin H-type lp_2633 44 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 28377048 Common - hypothetical protein lp_0091 4 None None None 28378590 Common - ABC transporter, permease protein lp_1944 12 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 28379071 Common - ring-cleaving dioxygenase (putative) lp_2528 40 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 28377271 Common sufI cell division protein SufI lp_0355 109 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 28377266 Common amtB ammonium transport protein lp_0349 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 28377869 Common - ABC transporter, permease protein lp_1075 80 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 28379452 Common - transcription regulator lp_3024 170 COG0583 LysR, Transcriptional regulator Transcription 28378944 Common atpB F0F1 ATP synthase subunit A lp_2370 199 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 28377442 Common - transport protein lp_0559 27 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 28378978 Nonpathogen - prophage Lp2 protein 44 lp_2413 1 None None None 28377242 Common - hypothetical protein lp_0320 33 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 28377381 Common argC1 N-acetyl-gamma-glutamyl-phosphate reductase lp_0487 191 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 28378822 Common - hypothetical protein lp_2224 9 None None None 28378489 Common - transcription regulator lp_1821 100 COG1846 MarR, Transcriptional regulators Transcription 28379980 Common - lipoprotein precursor, peptide binding protein OppA homolog lp_3686 124 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 28378496 Common msrA2 protein-methionine-S-oxide reductase lp_1835 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 28379942 Common dexB glucan 1,6-alpha-glucosidase lp_3641 157 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 28378681 Common cdsA phosphatidate cytidylyltransferase lp_2050 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 28379526 Common - cell surface protein precursor lp_3115 8 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 28378416 Common mvaK1 mevalonate kinase lp_1735 60 COG1577 ERG12, Mevalonate kinase Lipid metabolism 28378971 Nonpathogen - prophage Lp2 protein 51 lp_2406 1 None None None 28378599 Nonpathogen - ABC transporter, permease protein lp_1956 1 None None None 28378948 Common - SUA5 family translation factor (putative) lp_2376 237 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 28378575 Common nrpR2 negative regulator of proteolysis lp_1928 43 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 28377556 Nonpathogen - prophage Lp1 protein 61 lp_0684 1 None None None 28377814 Common - lipase/esterase (putative) lp_1002 34 COG0657 Aes, Esterase/lipase Lipid metabolism 28379766 Common - hypothetical protein lp_3438 76 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 28377063 Common thiD phosphomethylpyrimidine kinase lp_0114 216 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 28377418 Common argF ornithine carbamoyltransferase lp_0532 236 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 28378427 Common - hypothetical protein lp_1747 119 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 28378317 Common sunL rRNA methylase (putative) lp_1617 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 28378732 Common glnQ3 glutamine ABC transporter, ATP-binding protein lp_2110 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 28378384 Nonpathogen - integral membrane protein lp_1695 1 None None None 28377935 Common lys lysozyme (putative) lp_1158 23 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 28377962 Common rfbC dTDP-4-dehydrorhamnose 3,5-epimerase lp_1188 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 28379797 Common galE4 UDP-glucose 4-epimerase lp_3481 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 28377615 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase lp_0756 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 28378200 Nonpathogen - hypothetical protein lp_1484 1 None None None 28379632 Common crtN squalene synthase lp_3262 93 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 28379747 Common - transcription regulator lp_3415 111 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 28378582 Common - cell surface hydrolase (putative) lp_1935 10 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 28379885 Common - integral membrane protein lp_3577 7 COG2261 COG2261, Predicted membrane protein Function unknown 28377230 Common - DNA helicase (putative) lp_0308 102 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 28378442 Nonpathogen - hypothetical protein lp_1765 1 None None None 28379530 Common lepA2 GTP-binding protein LepA lp_3120 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 28379723 Common - prophage Lp4 protein 4 lp_3387 2 None None None 28378938 Common atpD F0F1 ATP synthase subunit beta lp_2364 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 28377695 Common pepR1 prolyl aminopeptidase lp_0853 77 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 28378680 Common - zinc-dependent protease, membrane associated (putative) lp_2049 204 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 28377278 Common - ribonucleoside hydrolase RihC lp_0363 87 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 28377333 Common plnX plantaricin biosynthesis protein PlnX (putative) lp_0430 53 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 28377847 Common rplF 50S ribosomal protein L6 lp_1051 245 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 28378215 Common narJ nitrate reductase, delta chain lp_1499 3 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 28378063 Nonpathogen - hypothetical protein lp_1313 1 None None None 28377235 Common ndh1 NADH dehydrogenase lp_0313 185 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 28377507 Nonpathogen - prophage Lp1 protein 10 lp_0633 1 None None None 28377192 Nonpathogen - hypothetical protein lp_0266 1 None None None 28377413 Common carA carbamoyl phosphate synthase small subunit lp_0527 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 28378812 Common brnQ2 branched-chain amino acid transport protein lp_2213 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 28377007 Common - hypothetical protein lp_0039 8 COG4853 COG4853, Uncharacterized protein conserved in bacteria Function unknown 28379365 Common - hydrolase, HAD superfamily, Cof family lp_2913 108 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28379833 Common pts31A PTS, EIIA lp_3519 130 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 28379281 Common aroC1 3-dehydroquinate dehydratase lp_2798 17 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 28378238 Nonpathogen - hypothetical protein lp_1525 3 None None None 28377053 Common - cobalt ABC transporter, ATP-binding protein (putative) lp_0100 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 28379691 Common - hypothetical protein lp_3343 80 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 28377199 Common - transcription regulator (putative) lp_0274 103 COG1309 AcrR, Transcriptional regulator Transcription 28378153 Common - hypothetical protein lp_1427 6 COG3613 COG3613, Nucleoside 2-deoxyribosyltransferase Nucleotide transport and metabolism 28377795 Common murE1 UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diami nopimelate ligase lp_0977 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 28379159 Common pts19A N-acetylglucosamine/galactosamine PTS, EIIA lp_2647 27 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 28378913 Common - hypothetical protein lp_2333 9 COG5506 COG5506, Uncharacterized conserved protein Function unknown 28378922 Common glpQ3 glycerophosphodiester phosphodiesterase lp_2344 65 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 28377018 Common - fumarate reductase, flavoprotein subunit precursor lp_0055 118 COG0431 COG0431, Predicted flavoprotein General function prediction only 28379928 Common - transcription regulator lp_3625 125 COG1609 PurR, Transcriptional regulators Transcription 28377524 Nonpathogen - prophage Lp1 protein 28 lp_0651 1 None None None 28378585 Common - transcription regulator lp_1938 192 COG0583 LysR, Transcriptional regulator Transcription 28377486 Common cysS cysteine--tRNA ligase lp_0610 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28379727 Nonpathogen - hypothetical protein lp_3391 1 None None None 28379978 Common - hypothetical protein lp_3683 68 COG1847 Jag, Predicted RNA-binding protein General function prediction only 28377390 Common - hypothetical protein lp_0499 14 None None None 28379014 Common - prophage Lp2 protein 6 lp_2451 41 COG4748 COG4748, Uncharacterized conserved protein Function unknown 28378691 Common plsC 1-acylglycerol-3-phosphate O-acyltransferase lp_2060 100 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 28378447 Common - ABC transporter, ATP-binding protein lp_1771 246 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 28377397 Nonpathogen - hypothetical protein lp_0509 1 None None None 28377317 Common plnP immunity protein PlnP, membrane-bound protease CAAX family lp_0412 8 None None None 28377373 Common - hypothetical protein lp_0479 9 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 28377983 Common - hypothetical protein lp_1210 6 COG4715 COG4715, Uncharacterized conserved protein Function unknown 28376982 Common ssb single-strand binding protein lp_0010 206 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 28377953 Common cps1C repeat unit transporter lp_1179 101 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 28378363 Common fabD [acyl-carrier protein] S-malonyltransferase lp_1673 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 28378033 Common - integrase/recombinase, fragment (putative) lp_1268 66 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 28378641 Nonpathogen - integral membrane protein lp_2004 1 None None None 28378359 Common - transcription regulator lp_1669 68 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 28377011 Common - transcription regulator lp_0046 5 COG1309 AcrR, Transcriptional regulator Transcription 28377820 Common dgk1 deoxyguanosine kinase lp_1011 40 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 28379776 Common - extracellular protein lp_3453 7 None None None 28377338 Common - transcription regulator lp_0435 98 COG2188 PhnF, Transcriptional regulators Transcription 28379126 Common - transcription regulator lp_2599 68 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 28377363 Common - zinc/iron ABC transporter, permease protein lp_0464 170 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 28377357 Common - hypothetical protein lp_0457 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 28377378 Common rimK ribosomal protein S6 modification protein lp_0484 97 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 28379023 Common - prophage Lp3 protein 19, head-to-tail joining lp_2462 3 None None None 28379646 Common - cation efflux protein lp_3280 26 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 28379905 Common - transcription regulator lp_3598 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 28378234 Common - oxidoreductase lp_1521 160 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 28379921 Common tal3 fructose-6-phosphate aldolase lp_3617 109 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 28378205 Common - hypothetical protein lp_1489 4 None None None 28378880 Nonpathogen - hypothetical protein lp_2289 1 None None None 28377248 Nonpathogen - hypothetical protein lp_0327 1 None None None 28378860 Common - phosphoesterase (putative) lp_2266 31 COG0622 COG0622, Predicted phosphoesterase General function prediction only 28377585 Common rimI2 ribosomal-protein-alanine N-acetyltransferase lp_0720 177 COG0456 RimI, Acetyltransferases General function prediction only 28377828 Common rpsL 30S ribosomal protein S12 lp_1025 237 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 28378228 Common thrS threonine--tRNA ligase 1 lp_1514 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28379062 Nonpathogen - hypothetical protein lp_2516 1 None None None 28378854 Nonpathogen - hypothetical protein lp_2260 1 None None None 28377000 Common map1 maltose phosphorylase lp_0028 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 28379476 Common copA copper transporting ATPase lp_3055 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 28377912 Common cydC cytochrome D ABC transporter, ATP-binding and permease protein lp_1128 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 28379102 Common - short-chain dehydrogenase/oxidoreductase lp_2568 229 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 28377605 Common pstE phosphate ABC transporter, substrate binding protein lp_0746 141 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 28378116 Common cysC adenylylsulfate kinase lp_1379 144 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 28377766 Common hsdS1 type Ic restriction-modification system, HsdS subunit lp_0940 83 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 28378673 Common infB translation initiation factor IF-2 lp_2040 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 28378715 Nonpathogen - hypothetical protein lp_2093 1 None None None 28379352 Common - oxidoreductase lp_2890 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 28377730 Common sugE GroEL supressor protein SugE lp_0898 131 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 28378627 Common - D-tyrosyl-tRNA deacylase lp_1986 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 28379395 Nonpathogen - hypothetical protein lp_2952 1 None None None 28378961 Common - ABC transporter, ATP-binding and permease protein lp_2395 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 28379139 Nonpathogen - hypothetical protein lp_2616 1 None None None 28378518 Common - transport protein lp_1863 209 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 28379532 Common - pyrophosphatase (putative) lp_3123 106 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 28379130 Common - transcription regulator lp_2603 76 COG1737 RpiR, Transcriptional regulators Transcription 28377306 Common - hydrolase, HAD superfamily, Cof family lp_0397 127 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 28378139 Common arcT transaminase lp_1410 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 28377286 Common glpD glycerol-3-phosphate dehydrogenase lp_0371 146 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 28378190 Common fecB iron chelatin ABC transporter, substrate binding protein (putative) lp_1473 70 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 28377755 Nonpathogen - hypothetical protein lp_0927 1 None None None 28378526 Common - ABC transporter, ATP-binding protein lp_1871 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 28377988 Common cps3A glycosyltransferase lp_1215 77 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 28377657 Common ung uracil-DNA glycosylase lp_0806 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 28378393 Common - integral membrane protein lp_1704 9 None None None 28377162 Common pts2A mannitol PTS, EIIA lp_0232 60 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 28379347 Nonpathogen - hypothetical protein lp_2883 1 None None None 28378213 Common narG nitrate reductase, alpha chain lp_1497 104 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 28379016 Common - prophage Lp2 protein 4 lp_2453 5 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 28378808 Common - Mg2+ and Co2+ transport protein lp_2206 51 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 28379931 Common bgl beta-glucosidase lp_3629 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 28378291 Nonpathogen - integral membrane protein lp_1590 1 None None None 28379233 Nonpathogen - integral membrane protein (putative) lp_2741 1 None None None 28379249 Common - O-acetyltransferase lp_2761 176 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 28379324 Common - transcription regulator lp_2854 109 COG0789 SoxR, Predicted transcriptional regulators Transcription 28379543 Common tkt3 transketolase lp_3135 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 28379637 Nonpathogen - hypothetical protein lp_3268 1 None None None 28379301 Common - purine nucleosidase lp_2825 87 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 28378814 Common rpsN2 ribosomal protein S14-2 lp_2216 207 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 28379097 Common hisK histidinol-phosphatase lp_2563 32 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 28379796 Common galT galactose-1-phosphate uridylyltransferase lp_3480 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 28379370 Common pepR2 prolyl aminopeptidase lp_2919 76 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 28379805 Common - oxidoreductase lp_3489 187 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 28377038 Common fusA1 elongation factor G lp_0076 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 28378472 Nonpathogen - hypothetical protein lp_1800 1 COG1598 COG1598, Uncharacterized conserved protein Function unknown 28377923 Common ligA DNA ligase (NAD+) lp_1145 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 28377737 Common pts12BCA beta-glucosides PTS, EIIBCA lp_0905 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28379422 Common zmp3 extracellular zinc metalloproteinase (putative) lp_2988 4 COG1913 COG1913, Predicted Zn-dependent proteases General function prediction only 28377926 Common gatA glutamyl-tRNA amidotransferase, subunit A lp_1148 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 28379389 Common - transcription regulator lp_2942 188 COG0583 LysR, Transcriptional regulator Transcription 28379810 Common aroE shikimate 5-dehydrogenase lp_3494 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 28377641 Common cggR central glycolytic genes regulator lp_0788 25 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 28377368 Common - integral membrane protein lp_0472 59 COG1434 COG1434, Uncharacterized conserved protein Function unknown 28377720 Common - hypothetical protein lp_0887 41 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 28377959 Nonpathogen cps1I polysaccharide polymerase lp_1185 2 None None None 28378475 Nonpathogen - hypothetical protein lp_1805 2 None None None 28379293 Nonpathogen - hypothetical protein lp_2814 1 None None None 28378790 Common - ADP-ribose pyrophosphatase lp_2183 164 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 28377690 Nonpathogen - hypothetical protein lp_0846 2 None None None 28378321 Common rpe ribulose-phosphate 3-epimerase lp_1621 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 28377108 Common dak1B glycerone kinase lp_0168 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 28379429 Common - integral membrane protein lp_2998 7 COG4300 CadD, Predicted permease, cadmium resistance protein Inorganic ion transport and metabolism 28377877 Common aroD1 shikimate 5-dehydrogenase lp_1084 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 28378885 Common - hypothetical protein lp_2299 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 28378504 Common hslU ATP-dependent protease ATP-binding subunit lp_1845 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 28379619 Nonpathogen - hypothetical protein lp_3243 1 None None None 28378982 Common - prophage Lp2 protein 40 lp_2417 6 None None None 28377729 Common - NTP pyrophosphohydrolase (putative) lp_0897 74 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 28378968 Nonpathogen - prophage Lp2 protein 54 lp_2403 1 None None None 28378934 Common mreB2 cell shape determining protein MreB lp_2359 220 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 28377254 Common pepD2 dipeptidase lp_0334 24 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 28379242 Common - hypothetical protein lp_2753 3 None None None 28379955 Common srlM2 sorbitol operon activator lp_3655 9 COG4578 GutM, Glucitol operon activator Transcription 28377436 Common - hypothetical protein lp_0552 8 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 28379630 Common - DegV family protein lp_3256 48 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 28378154 Nonpathogen - hypothetical protein lp_1428 1 None None None 28377948 Common - integral membrane protein lp_1174 98 COG1295 Rbn, Predicted membrane protein Function unknown 28379207 Common - transport protein lp_2712 142 COG2252 COG2252, Permeases General function prediction only 28378734 Nonpathogen - hypothetical protein lp_2112 1 None None None 28378801 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase lp_2197 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 28379830 Common - putative frv operon regulatory protein lp_3516 3 COG3711 BglG, Transcriptional antiterminator Transcription 28377409 Common alr alanine racemase lp_0523 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 28377777 Common - acyl carrier protein phosphodiesterase lp_0955 94 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 28377456 Common pts9AB mannose PTS, EIIAB lp_0575 80 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 28378401 Common - prenyltransferase lp_1715 30 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 28378286 Nonpathogen - hypothetical protein lp_1583 5 None None None 28378666 Common aroI shikimate kinase lp_2033 195 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 28379752 Common - extracellular protein, gamma-D-glutamate-meso-diaminopimelate muropeptidase (putative) lp_3421 93 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 28377404 Common htpX heat shock protein HtpX lp_0516 182 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 28379359 Common - transcription regulator lp_2903 23 COG0640 ArsR, Predicted transcriptional regulators Transcription 28377226 Common - extracellular protein lp_0304 6 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 28379817 Common - hypothetical protein lp_3501 18 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 28377327 Common plnH bacteriocin ABC transporter, accessory factor PlnH lp_0424 8 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 28378098 Common pltK histidine protein kinase; sensor protein lp_1355 20 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 28379589 Common - transcription regulator lp_3206 190 COG0583 LysR, Transcriptional regulator Transcription 28378303 Common ispA geranyltranstransferase lp_1602 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 28379125 Common pflB1 formate C-acetyltransferase lp_2598 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 28377142 Nonpathogen - hypothetical protein lp_0207 1 None None None 28379112 Common glpQ4 glycerophosphodiester phosphodiesterase lp_2582 52 COG4781 COG4781, Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase Energy production and conversion 28378750 Common comEA ComE operon protein 1 lp_2131 111 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 28379199 Common pyrD dihydroorotate oxidase lp_2699 231 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 28379658 Common folP dihydropteroate synthase lp_3294 217 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 28379770 Common pepO endopeptidase PepO lp_3445 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 28378168 Common - cell surface protein precursor lp_1448 8 None None None 28379460 Nonpathogen - hypothetical protein lp_3032 1 COG4925 COG4925, Uncharacterized conserved protein Function unknown 28378085 Common - transcription regulator lp_1341 36 COG0789 SoxR, Predicted transcriptional regulators Transcription 28379448 Common tag2 DNA-3-methyladenine glycosylase I lp_3020 131 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 28379434 Nonpathogen - hypothetical protein lp_3004 1 None None None 28378463 Common - ADP-ribose pyrophosphatase (putative) lp_1790 8 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 28379697 Nonpathogen - hypothetical protein lp_3350 1 None None None 28378708 Common - integral membrane protein lp_2084 8 None None None 28379594 Common - amino acid ABC transporter, substrate binding protein lp_3214 149 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 28377885 Common citG triphosphoribosyl-dephospho-CoA synthase lp_1093 47 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 28377577 Common phnW (2-aminoethyl)phosphonate--pyruvate aminotransferase lp_0710 161 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 28379379 Common - protein containing diguanylate cyclase/phosphodiesterase domain 1 (GGDEF) lp_2929 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 28379680 Common cadA cadmium-/zinc-/cobalt-transporting ATPase lp_3327 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 28379896 Common pox5 pyruvate oxidase lp_3589 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 28377782 Common - hypothetical protein lp_0961 6 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 28379684 Nonpathogen - hypothetical protein lp_3333 1 None None None 28377209 Common - transcription regulator lp_0285 93 COG1737 RpiR, Transcriptional regulators Transcription 28377898 Nonpathogen - hypothetical protein lp_1110 1 None None None 28378348 Common trpF phosphorybosylanthranilate isomerase lp_1656 167 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 28378044 Nonpathogen - hypothetical protein lp_1284 1 None None None 28378606 Common dnaG DNA primase DnaG lp_1963 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 28378904 Common valS valyl-tRNA synthetase lp_2322 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 28379983 Nonpathogen rpmH ribosomal protein L34 lp_3688a 1 None None None 28377052 Nonpathogen - hypothetical protein lp_0099 1 None None None 28377062 Common thiM hydroxyethylthiazole kinase lp_0113 78 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 28377182 Common cysK cysteine synthase lp_0256 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 28377189 Common treA alpha, alpha-phosphotrehalase lp_0263 161 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 28379674 Common - oxidoreductase lp_3318 199 COG4989 COG4989, Predicted oxidoreductase General function prediction only 28379272 Common panE2 2-dehydropantoate 2-reductase lp_2788 77 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 28377798 Common - integral membrane protein lp_0981 24 COG4392 COG4392, Predicted membrane protein Function unknown 28378540 Common - integral membrane protein lp_1887 15 COG3601 COG3601, Predicted membrane protein Function unknown 28378856 Common - mechanosensitive transport protein lp_2262 219 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 28379517 Common fhuC ferrichrome ABC transporter, ATP-binding protein lp_3104 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 28379689 Common - cell surface hydrolase, membrane-bound (putative) lp_3341 10 COG4814 COG4814, Uncharacterized protein with an alpha/beta hydrolase fold General function prediction only 28377546 Nonpathogen - prophage Lp1 protein 51 lp_0674 2 None None None 28378754 Common - hypothetical protein lp_2135 11 COG4471 COG4471, Uncharacterized protein conserved in bacteria Function unknown 28377770 Common - hypothetical protein lp_0947 3 None None None 28377950 Common glf1 UDP-galactopyranose mutase lp_1176 60 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 28378420 Common aspB aspartate aminotransferase lp_1739 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 28379380 Common - protein containing diguanylate cyclase/phosphodiesterase domain 2 (EAL) lp_2930 88 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 28379820 Nonpathogen - integral membrane protein (putative) lp_3504 1 None None None 28377663 Common - oxidoreductase (putative) lp_0813 134 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 28378011 Common - extracellular protein, gamma-D-glutamate-meso-diaminopimelate muropeptidase (putative) lp_1242 117 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 28377880 Common - cation transport protein lp_1087 75 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 28379553 Nonpathogen baiE bile acid 7-alpha-dehydratase lp_3159 4 None None None 28379049 Common pgi glucose-6-phosphate isomerase lp_2502 163 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 28379510 Nonpathogen - transcription regulator (putative) lp_3097 4 COG1309 AcrR, Transcriptional regulator Transcription 28377023 Common - short-chain dehydrogenase/oxidoreductase lp_0060 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 28378770 Common - hypothetical protein lp_2157 11 COG5503 COG5503, Uncharacterized conserved small protein Function unknown 28378749 Common comEB dCMP deaminase lp_2130 89 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 28377005 Common hpk1 histidine protein kinase; sensor protein lp_0037 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 28378418 Common dinG ATP-dependent helicase DinG lp_1737 204 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 28379823 Common pts29C cellobiose PTS, EIIC lp_3507 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 28379939 Common rrp12 response regulator lp_3638 190 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 28378024 Common - transcription regulator lp_1258 191 COG0583 LysR, Transcriptional regulator Transcription 28377178 Common - hypothetical protein lp_0252 15 None None None 28377973 Common cps2C exopolysaccharide biosynthesis protein lp_1199 40 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 28379411 Common - ABC transporter, substrate binding protein lp_2974 53 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 28378183 Common feoB ferrous iron transport protein B lp_1466 158 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 28379488 Common - hypothetical protein lp_3071 24 COG4832 COG4832, Uncharacterized conserved protein Function unknown 28379492 Common - cell surface protein (putative) lp_3075 23 None None None 28377891 Common - cation transport protein lp_1102 79 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 28379508 Common - transcription regulator (putative) lp_3095 139 COG1733 COG1733, Predicted transcriptional regulators Transcription 28379073 Common pts18CBA N-acetylglucosamine and glucose PTS, EIICBA lp_2531 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 28378261 Common - acylphosphatase (putative) lp_1554 79 COG1254 AcyP, Acylphosphatases Energy production and conversion 28379568 Common - extracellular protein lp_3178 5 None None None 28379101 Common - transcription regulator lp_2567 115 COG0789 SoxR, Predicted transcriptional regulators Transcription 28379757 Common - metal-dependent hydrolase (putative), N-terminal fragment lp_3427a 2 None None None 28378929 Common - amino acid ABC transporter, ATP-binding protein lp_2352 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 28377496 Common rplA 50S ribosomal protein L1 lp_0620 235 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 28377111 Common gplF2 glycerol uptake facilitator protein lp_0171 128 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 28378776 Common prs2 ribose-phosphate pyrophosphokinase lp_2166 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 28378838 Nonpathogen - hypothetical protein lp_2239 1 None None None 28378554 Common pepT peptidase T lp_1904 58 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 28377740 Common - DNA helicase (putative) lp_0910 41 COG3973 COG3973, Superfamily I DNA and RNA helicases General function prediction only 28379090 Common hisF cyclase lp_2554 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 28379473 Common - extracellular protein lp_3050 4 None None None 28378253 Common cshA2 recombination factor protein RarA lp_1543 244 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 28379172 Common - integral membrane protein lp_2663 6 None None None 28378757 Common - integral membrane protein lp_2141 6 None None None 28379221 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase lp_2727 198 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 28379961 Common rbsR ribose operon repressor lp_3661 128 COG1609 PurR, Transcriptional regulators Transcription 28377727 Common - transcription regulator (putative) lp_0895 38 COG1309 AcrR, Transcriptional regulator Transcription 28378847 Common rbsK2 ribokinase lp_2251 186 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 28377041 Common - acetyltransferase (GNAT) family (putative) lp_0080 46 COG0456 RimI, Acetyltransferases General function prediction only 28379410 Common - ABC transporter, permease protein lp_2973 133 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only