Vibrio vulnificus CMCP6 chromosome II, complete sequence NC_004460 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 27366534 Common - Anti-sigma regulatory factor VV2_0075 38 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 27366629 Common - Transcriptional regulator VV2_0173 181 COG0583 LysR, Transcriptional regulator Transcription 27366562 Common - Acetyltransferase VV2_0105 203 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 27366896 Common - Predicted Co/Zn/Cd cation transporter VV2_0459 35 COG3965 COG3965, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 27366469 Common - hypothetical protein VV2_0006 113 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 27367641 Common - FOG: EAL domain protein VV2_1264 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 27367250 Common - Non-ribosomal peptide synthetase modules VV2_0844 57 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 27366575 Pathogen - hypothetical protein VV2_0119 1 None None None 27367236 Common - Phosphopantetheinyl transferase component of siderophore synthetase VV2_0829 37 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 27367935 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_1590 180 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 27366601 Common - AraC-type DNA-binding domain-containing protein VV2_0145 41 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27367227 Common - hypothetical protein VV2_0819 24 None None None 27367755 Common - Transcriptional regulator VV2_1391 161 COG0583 LysR, Transcriptional regulator Transcription 27366494 Common - Zinc metalloprotease VV2_0032 46 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 27367687 Pathogen - hypothetical protein VV2_1315 1 None None None 27366665 Common - Response regulator VV2_0210 215 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 27366917 Common - Membrane-fusion protein VV2_0483 130 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27366571 Common - hypothetical protein VV2_0115 12 None None None 27367380 Common - TRAP-type uncharacterized transport system, periplasmic component VV2_0985 82 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 27367941 Common - Flavodoxin reductase family 1 protein VV2_1598 164 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 27367971 Common - Predicted membrane protein VV2_1630 27 COG3619 COG3619, Predicted membrane protein Function unknown 27367206 Common - L-lactate permease VV2_0797 102 COG1620 LldP, L-lactate permease Energy production and conversion 27367217 Common - Zn-dependent hydrolase VV2_0809 111 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 27367879 Common - ABC-type cobalt transport system VV2_1532 72 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 27366510 Common - hypothetical protein VV2_0050 41 COG1288 COG1288, Predicted membrane protein Function unknown 27367151 Common - N-acetylglucosamine-6-phosphate deacetylase VV2_0736 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 27366774 Common - hypothetical protein VV2_0331 7 COG3111 COG3111, Uncharacterized conserved protein Function unknown 27367938 Common - hypothetical protein VV2_1594 61 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 27367412 Common - Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC VV2_1021 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 27366844 Common glpT sn-glycerol-3-phosphate transporter VV2_0405 91 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 27366645 Common - Predicted transcriptional regulator VV2_0189 103 COG1396 HipB, Predicted transcriptional regulators Transcription 27367491 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease component VV2_1102 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 27366663 Common - ABC-type Fe3+ transport system, periplasmic component VV2_0208 38 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 27366620 Common - FOG: TPR repeat protein VV2_0164 15 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 27367131 Pathogen - Outer membrane receptor protein VV2_0713 1 None None None 27367740 Common - Uridine phosphorylase VV2_1373 101 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 27366813 Common - FOG: WD40 repeat VV2_0373 19 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 27367173 Common - Na+-driven multidrug efflux pump VV2_0760 139 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 27367259 Common - Uncharacterized copper-binding protein VV2_0853 30 COG4454 COG4454, Uncharacterized copper-binding protein Inorganic ion transport and metabolism 27367162 Pathogen - hypothetical protein VV2_0748 1 None None None 27367809 Common - hypothetical protein VV2_1455 58 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 27367220 Common - Small-conductance mechanosensitive channel VV2_0812 12 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 27366670 Common - Formyltetrahydrofolate synthetase VV2_0216 88 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 27367626 Common - transcriptional regulator MalT VV2_1247 103 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 27367919 Common - Membrane-fusion protein VV2_1573 114 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27366902 Common - Aromatic ring-cleaving dioxygenase VV2_0466 14 COG3805 DodA, Aromatic ring-cleaving dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 27366992 Common - hypothetical protein VV2_0562 5 None None None 27366608 Common - Arylsulfatase regulator VV2_0152 104 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 27367449 Common - hypothetical protein VV2_1059 3 None None None 27366878 Common - hypothetical protein VV2_0441 46 COG3523 IcmF, Uncharacterized protein conserved in bacteria Function unknown 27367793 Common - Transcriptional regulator VV2_1431 2 COG1309 AcrR, Transcriptional regulator Transcription 27366876 Common - Serine/threonine protein phosphatase VV2_0439 137 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 27367245 Common - isochorismate-pyruvate lyase VV2_0839 31 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 27367552 Common - Predicted P-loop ATPase fused to an acetyltransferase VV2_1171 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 27366940 Common - Putative NADP-dependent oxidoreductase VV2_0507 101 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 27367747 Common - Argininosuccinate synthase VV2_1381 178 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 27367656 Common - hypothetical protein VV2_1280 23 COG3915 COG3915, Uncharacterized protein conserved in bacteria Function unknown 27367086 Common - Endonuclease I VV2_0661 29 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 27367697 Common - ABC-type sugar transport system, periplasmic component VV2_1326 80 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 27367603 Pathogen - hypothetical protein VV2_1223 1 None None None 27366695 Common - hypothetical protein VV2_0246 6 None None None 27367277 Common - ABC-type sugar transport system, periplasmic component VV2_0872 89 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 27367635 Common - hypothetical protein VV2_1258 19 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 27366812 Common - Methyl-accepting chemotaxis protein VV2_0372 156 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367646 Common - Predicted Zn-dependent peptidase VV2_1270 199 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 27366926 Common - Acyl-CoA dehydrogenase VV2_0492 168 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 27367106 Common - ABC-type sulfate transport system, periplasmic component VV2_0685 93 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 27367982 Common - Nucleoside permease VV2_1641 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 27367822 Common - putative hydrolase VV2_1469 62 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 27366997 Common - Cytochrome c, mono- and diheme variants VV2_0568 160 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 27366762 Common - hypothetical protein VV2_0319 6 None None None 27367460 Common - glucuronate isomerase VV2_1070 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 27367706 Common - Uncharacterized FAD-dependent dehydrogenase VV2_1336 83 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 27367304 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase VV2_0904 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 27366751 Pathogen - hypothetical protein VV2_0307 1 None None None 27367405 Common - iron-hydroxamate transporter permease subunit VV2_1013 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 27367662 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta-galactosidase VV2_1287 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 27368021 Common - D-alanyl-D-alanine carboxypeptidase VV2_1681 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 27366867 Common - ATPase with chaperone activity, ATP-binding subunit VV2_0430 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 27367870 Common - Methyl-accepting chemotaxis protein VV2_1523 8 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366507 Common - hypothetical protein VV2_0047 16 COG3097 COG3097, Uncharacterized protein conserved in bacteria Function unknown 27366639 Common - Deoxycytidylate deaminase VV2_0183 34 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 27366835 Common - hypothetical protein VV2_0396 140 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 27367421 Common - Diaminopimelate decarboxylase VV2_1030 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 27367065 Pathogen - hypothetical protein VV2_0639 1 None None None 27367865 Common - Outer membrane protein, putative VV2_1518 51 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 27367324 Common - Small-conductance mechanosensitive channel VV2_0925 134 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 161501864 Common - hypothetical protein VV2_0460 49 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 27366966 Common - hypothetical protein VV2_0533 10 None None None 27367616 Common - Amino acid transporter VV2_1236 165 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 27367349 Pathogen - hypothetical protein VV2_0954 1 None None None 27366769 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_0326 44 None None None 27366630 Common - hypothetical protein VV2_0174 80 COG2128 COG2128, Uncharacterized conserved protein Function unknown 27366826 Common - FOG: GGDEF domain VV2_0387 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27368010 Common - ABC-type Fe3+ transport system, permease component VV2_1670 217 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 27366947 Common - Phosphomannose isomerase VV2_0514 41 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 27367047 Common - Transposase VV2_0619 61 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 27366514 Common - NTP pyrophosphohydrolase VV2_0054 181 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 27367958 Common - Putative heme iron utilization protein VV2_1616 18 COG3721 HugX, Putative heme iron utilization protein Inorganic ion transport and metabolism 27366531 Common - Methyl-accepting chemotaxis protein VV2_0072 163 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366859 Common - hypothetical protein VV2_0422 2 None None None 27367266 Common - Phosphotransferase system mannitol VV2_0860 64 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 27367995 Common - Transcriptional regulator VV2_1654 186 COG0583 LysR, Transcriptional regulator Transcription 27367411 Common - Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID VV2_1020 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 27366529 Common - Histone acetyltransferase HPA2 VV2_0070 19 COG0456 RimI, Acetyltransferases General function prediction only 27366885 Common - Transcriptional regulator VV2_0448 90 COG1309 AcrR, Transcriptional regulator Transcription 27367613 Common - Type II secretory pathway protein VV2_1233 111 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 27366627 Common - Transcriptional regulator VV2_0171 4 None None None 27366900 Common - Signal transduction histidine kinase VV2_0464 159 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 27367578 Common - Na+/glutamate symporter VV2_1198 53 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 27368017 Common - L-serine deaminase VV2_1677 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 27366781 Common - Metal-dependent hydrolase VV2_0338 8 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 27366994 Common - Heme/copper-type cytochrome/quinol oxidase, subunit 3 VV2_0565 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 27367015 Common - Permease of the major facilitator superfamily VV2_0586 216 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 27367149 Common - N-acetylmannosamine-6-phosphate 2-epimerase VV2_0734 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 27367885 Common - ATP-dependent transcriptional regulator VV2_1538 2 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 27368009 Common - ABC-type spermidine/putrescine transport system, ATPase component VV2_1669 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 27367118 Common - Putative GTPase VV2_0699 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 27367004 Common - 2-keto-4-pentenoate hydratase VV2_0575 178 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 27366582 Pathogen - hypothetical protein VV2_0126 1 None None None 27367135 Common - hypothetical protein VV2_0717 2 None None None 27367053 Common - Methyl-accepting chemotaxis protein VV2_0626 3 None None None 27367672 Common - Transcriptional regulator VV2_1297 129 COG1609 PurR, Transcriptional regulators Transcription 27367844 Common - Plasmid stabilization system protein VV2_1493 11 COG3668 ParE, Plasmid stabilization system protein General function prediction only 27367745 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_1379 98 None None None 27367623 Common - Predicted membrane protein VV2_1243 50 COG2035 COG2035, Predicted membrane protein Function unknown 27366921 Common - hypothetical protein VV2_0487 3 None None None 27366806 Common - hypothetical protein VV2_0365 60 COG1432 COG1432, Uncharacterized conserved protein Function unknown 27367326 Common - Cation/multidrug efflux pump VV2_0928 179 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 27366788 Common - Rhodanese-related sulfurtransferase VV2_0346 242 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 27366520 Common - ABC-type ribose transport system, auxiliary component VV2_0061 48 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 27366807 Common - hypothetical protein VV2_0366 7 None None None 27367462 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase VV2_1072 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 27367681 Common - Multidrug resistance efflux pump VV2_1308 142 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27367287 Common - Mg2+ and Co2+ transporter VV2_0884 2 None None None 27366799 Common - anaerobic C4-dicarboxylate transporter VV2_0358 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 27367509 Common - Membrane-fusion protein VV2_1125 122 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27367862 Common - Toxin secretion ATP-binding protein VV2_1515 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 27366596 Pathogen - hypothetical protein VV2_0140 2 None None None 27367977 Common - Glycosyltransferase involved in cell wall biogenesis VV2_1636 16 COG4262 COG4262, Predicted spermidine synthase with an N-terminal membrane domain General function prediction only 27366909 Common - Electron transfer flavoprotein, beta subunit VV2_0474 149 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 27367365 Common - Predicted hydrolase/acyltransferase VV2_0970 10 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 27367022 Common - Putative translation initiation inhibitor, yjgF family VV2_0593 149 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 27367813 Common - Outer membrane receptor for ferrienterochelin and colicins VV2_1460 118 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 27367554 Common - ATPase involved in chromosome partitioning VV2_1173 193 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 27367397 Common - ABC-type antimicrobial peptide transport system, permease component VV2_1005 149 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 27367714 Common - nitric oxide reductase VV2_1344 204 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 27367660 Common - ABC-type sugar transport system, permease component VV2_1284 165 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 27367040 Common - acetyltransferase VV2_0612 41 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 27366655 Common - fructose-specific PTS IIA/HPr components VV2_0200 112 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 27367984 Common - Alkylated DNA repair protein VV2_1643 41 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 27367156 Common - acetoacetyl-CoA reductase VV2_0742 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 27366932 Common - Enoyl-CoA hydratase/carnithine racemase VV2_0498 183 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 161501857 Common lacZ beta-D-galactosidase VV2_1327 72 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 27367703 Pathogen - hypothetical protein VV2_1333 1 None None None 27366956 Common - Outer membrane protein VV2_0523 129 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 27366647 Common - Secreted trypsin-like serine protease VV2_0191 19 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 27367502 Common - Delta 1-pyrroline-5-carboxylate dehydrogenase VV2_1117 31 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 27367312 Common - hypothetical protein VV2_0912 45 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 27366473 Common glpA sn-glycerol-3-phosphate dehydrogenase subunit A VV2_0010 167 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 27367778 Common - Response regulator VV2_1414 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 27366492 Common - Cation/multidrug efflux pump VV2_0030 180 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 27366701 Common - hypothetical protein VV2_0252 83 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 27367335 Common - Permease of the major facilitator superfamily VV2_0937 3 None None None 27367604 Common - Rhs family protein VV2_1224 77 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 27366746 Pathogen - hypothetical protein VV2_0302 1 None None None 27367075 Common - Methyl-accepting chemotaxis protein VV2_0649 21 None None None 27368012 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_1672 45 COG2510 COG2510, Predicted membrane protein Function unknown 27367296 Common - Predicted transcriptional regulator VV2_0894 142 COG0640 ArsR, Predicted transcriptional regulators Transcription 27367655 Common - FOG: GGDEF domain VV2_1279 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367829 Common - Lactoylglutathione lyase VV2_1477 49 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 27367234 Common - Predicted phosphatase VV2_0827 64 COG3211 PhoX, Predicted phosphatase General function prediction only 27367571 Common - Predicted Zn-dependent hydrolase of the beta-lactamase fold VV2_1191 3 None None None 27366838 Common - Acetyltransferase VV2_0399 59 COG0456 RimI, Acetyltransferases General function prediction only 27366933 Common - Isopropylmalate/homocitrate/citramalate synthase VV2_0499 87 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 27367199 Common - cytosine deaminase VV2_0789 71 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 27367692 Common - Membrane-fusion protein VV2_1321 98 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27366667 Common - AraC-type DNA-binding domain-containing protein VV2_0212 124 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27367851 Common - Transcriptional regulator, LysR family VV2_1503 130 COG0583 LysR, Transcriptional regulator Transcription 27367125 Pathogen - hypothetical protein VV2_0707 1 None None None 27366541 Common - Transcriptional regulator VV2_0083 155 COG0583 LysR, Transcriptional regulator Transcription 27367303 Common malS periplasmic alpha-amylase precursor VV2_0903 156 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 27366720 Common - Allophanate hydrolase subunit 1 VV2_0272 99 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 27367521 Common - hypothetical protein VV2_1137 37 COG1434 COG1434, Uncharacterized conserved protein Function unknown 27367110 Pathogen - Transcriptional regulator VV2_0689 1 None None None 27367282 Common - tyrosyl-tRNA synthetase VV2_0878 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 27367073 Common - Thiol-disulfide isomerase VV2_0647 14 None None None 27367492 Common - ABC-type dipeptide transport system, periplasmic component VV2_1104 143 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 27367738 Common - hypothetical protein VV2_1371 4 None None None 27366729 Common - hypothetical protein VV2_0281 2 None None None 27366733 Pathogen - hypothetical protein VV2_0286 1 None None None 27367472 Common araD L-ribulose-5-phosphate 4-epimerase VV2_1082 121 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 27367058 Common - hypothetical protein VV2_0632 8 None None None 27367092 Common - Integrase VV2_0667 24 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 27367545 Common - Methylase of chemotaxis methyl-accepting protein VV2_1163 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 27367318 Common - hypothetical protein VV2_0918 9 None None None 27367008 Common - Thiol-disulfide isomerase VV2_0579 156 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 27366981 Common - Chitinase VV2_0549 43 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 27366547 Common - Flp pilus assembly protein VV2_0089 156 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 27367294 Common - Diadenosine tetraphosphate hydrolase VV2_0892 91 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 27366846 Common - Predicted Zn-dependent protease VV2_0408 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 27366635 Common - ABC-type multidrug transport system, ATPase and permease component VV2_0179 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 27366999 Common - Histone acetyltransferase HPA2 VV2_0570 30 COG0456 RimI, Acetyltransferases General function prediction only 27367653 Common - Signal transduction histidine kinase VV2_1277 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27367608 Common - hypothetical protein VV2_1228 17 None None None 27366863 Common - NAD/NADP transhydrogenase beta subunit VV2_0426 2 None None None 27367531 Pathogen - hypothetical protein VV2_1147 1 None None None 27366612 Common - hypothetical protein VV2_0156 6 None None None 27367506 Common - pyridoxamine 5'-phosphate oxidase VV2_1122 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 27366687 Common - Predicted ATP-dependent endonuclease of the OLD family VV2_0236 31 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 27367717 Common - DNA-binding HTH domain-containing protein VV2_1347 16 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 27366675 Common - Response regulator VV2_0221 131 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 27367517 Pathogen - hypothetical protein VV2_1133 1 None None None 27367056 Pathogen - hypothetical protein VV2_0630 1 None None None 27367917 Common - Calcium binding protein VV2_1571 24 None None None 27367377 Common - Acyl-CoA synthetase VV2_0982 2 None None None 27367763 Common - hypothetical protein VV2_1399 6 None None None 27367359 Common - Transcriptional regulator VV2_0964 178 COG0583 LysR, Transcriptional regulator Transcription 27367596 Common - Predicted hydrolase or acyltransferase VV2_1216 30 COG2267 PldB, Lysophospholipase Lipid metabolism 27367624 Pathogen - hypothetical protein VV2_1244 1 None None None 27367407 Common - Outer membrane receptor protein VV2_1016 108 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 27367252 Common - Glutathione synthase VV2_0846 162 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 27367083 Common - hypothetical protein VV2_0658 12 None None None 27367061 Common - ATPase involved in DNA repair VV2_0635 25 COG2433 COG2433, Uncharacterized conserved protein Function unknown 27367254 Common - Zn-dependent hydrolase VV2_0848 28 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 27366898 Common - isoprenoid biosynthesis protein with amidotransferase-like domain VV2_0462 40 COG3155 ElbB, Uncharacterized protein involved in an early stage of isoprenoid biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 27366680 Common - FOG: EAL domain protein VV2_0228 148 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 27367208 Common - hypothetical protein VV2_0799 95 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 27366564 Pathogen - Predicted pyrophosphatase VV2_0107 1 COG1694 MazG, Predicted pyrophosphatase General function prediction only 27367129 Common - Integrase VV2_0711 132 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 27367013 Pathogen - hypothetical protein VV2_0584 1 None None None 27367694 Common - Transcriptional regulator VV2_1323 128 COG1609 PurR, Transcriptional regulators Transcription 27367947 Common - Leucine-rich repeat protein VV2_1604 3 None None None 27367937 Common - Predicted deacylase VV2_1593 11 COG3608 COG3608, Predicted deacylase General function prediction only 27367699 Common - hypothetical protein VV2_1328 4 None None None 27366677 Common - Methyl-accepting chemotaxis protein VV2_0224 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366573 Common - Hydroxymethylglutaryl-CoA reductase VV2_0117 41 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 27367601 Pathogen - High-affinity K+ transport system, ATPase chain B VV2_1221 1 None None None 27367753 Common - Transcriptional regulator VV2_1388 81 COG1309 AcrR, Transcriptional regulator Transcription 27367229 Common - FOG: EAL domain protein VV2_0821 160 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 27366689 Common - Membrane protein TerC VV2_0239 96 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 27367538 Common - Membrane-fusion protein VV2_1156 10 None None None 27367998 Common - Phosphoenolpyruvate-protein kinase VV2_1657 6 None None None 27367124 Common - hypothetical protein VV2_0706 11 None None None 27366819 Common - Response regulator VV2_0379 218 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 27366532 Common - Anti-anti-sigma regulatory factor VV2_0073 51 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 27366603 Common - Superfamily II DNA and RNA helicase VV2_0147 243 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 27367152 Common - ABC-type uncharacterized transport system, periplasmic component VV2_0738 96 COG4533 COG4533, ABC-type uncharacterized transport system, periplasmic component General function prediction only 27367643 Common - putative glutathione S-transferase YghU VV2_1267 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 27367389 Common - Multidrug resistance efflux pump VV2_0994 144 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27367402 Common - hypothetical protein VV2_1010 6 None None None 27367973 Common - hypothetical protein VV2_1632 2 None None None 27366821 Common - Arginase/agmatinase/formimionoglutamate hydrolase, arginase family VV2_0381 3 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 27366772 Common - ABC-type molybdate transport system, periplasmic component VV2_0329 119 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 27367161 Pathogen - SH3 domain protein VV2_0747 1 None None None 27367669 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component VV2_1294 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 27366748 Common - hypothetical protein VV2_0304 3 None None None 27366753 Pathogen - hypothetical protein VV2_0310 1 COG3140 COG3140, Uncharacterized protein conserved in bacteria Function unknown 27367610 Common malE maltose ABC transporter periplasmic protein VV2_1230 85 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 27367474 Common ulaD 3-keto-L-gulonate-6-phosphate decarboxylase VV2_1084 56 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 27367541 Common - Anti-anti-sigma regulatory factor VV2_1159 27 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 27367708 Common - hypothetical protein VV2_1338 137 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 27366661 Common - pyruvate kinase VV2_0206 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 27367863 Common - Secretion protein, HlyD family VV2_1516 131 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27367212 Common - Uncharacterized protein containing a von Willebrand factor type A (vWA) domain VV2_0803 42 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 27366828 Common - Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenase VV2_0389 46 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 27366509 Common - Predicted deacylase VV2_0049 53 COG3608 COG3608, Predicted deacylase General function prediction only 27367147 Common - TRAP-type C4-dicarboxylate transport system, small permease component VV2_0732 63 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 27367831 Common - Permease of the major facilitator superfamily VV2_1479 147 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 161501866 Common - hypothetical protein VV2_0273 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 27367306 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_0906 90 COG2962 RarD, Predicted permeases General function prediction only 27367807 Common - Permease of the major facilitator superfamily VV2_1453 37 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 27367423 Common - Alkyl sulfatase VV2_1032 45 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 27366545 Pathogen - ATPase with chaperone activity VV2_0087 1 COG5461 COG5461, Type IV pili component Cell motility and secretion 27367144 Common - Transcriptional regulator VV2_0729 108 COG1737 RpiR, Transcriptional regulators Transcription 27366637 Common - Inorganic pyrophosphatase/exopolyphosphatase VV2_0181 12 None None None 27367342 Common - Predicted DNA-binding protein VV2_0946 24 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 27366502 Common - Methyl-accepting chemotaxis protein VV2_0042 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367921 Common - Membrane protein involved in the export of O-antigen and teichoic acid VV2_1575 26 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 27367067 Common - hypothetical protein VV2_0641 26 None None None 27366968 Common - Predicted transcriptional regulator VV2_0535 7 None None None 27367243 Common - Siderophore-interacting protein VV2_0837 63 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 27366735 Pathogen - hypothetical protein VV2_0289 1 None None None 27367241 Common - Isochorismate synthase VV2_0835 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 27367928 Common - Sugar transferase involved in lipopolysaccharide synthesis VV2_1582 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 27367784 Common - 1,4-alpha-glucan branching enzyme VV2_1421 15 None None None 27367350 Common - hypothetical protein VV2_0955 2 None None None 27367175 Common - hypothetical protein VV2_0762 7 None None None 27367442 Common - Putative threonine efflux protein VV2_1051 111 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 27367894 Common - Protease II VV2_1548 106 COG1770 PtrB, Protease II Amino acid transport and metabolism 27367279 Common - Transcriptional regulator VV2_0874 178 COG0583 LysR, Transcriptional regulator Transcription 27367454 Common - mannonate dehydratase VV2_1064 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 27367860 Common - hypothetical protein VV2_1513 25 COG3111 COG3111, Uncharacterized conserved protein Function unknown 27367586 Common - Transcriptional regulator VV2_1206 174 COG0583 LysR, Transcriptional regulator Transcription 27367523 Common - tRNA and rRNA cytosine-C5-methylase VV2_1139 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 27366950 Common - hypothetical protein VV2_0517 15 COG2966 COG2966, Uncharacterized conserved protein Function unknown 27367369 Common - Zinc metalloprotease VV2_0974 48 COG3227 LasB, Zinc metalloprotease (elastase) Amino acid transport and metabolism 27366810 Common nirD nitrite reductase small subunit VV2_0369 45 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 27367215 Common - Outer membrane protein VV2_0807 2 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 27366693 Common - hypothetical protein VV2_0244 9 COG4538 COG4538, Uncharacterized conserved protein Function unknown 27366718 Common - hypothetical protein VV2_0270 8 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 27367710 Pathogen - hypothetical protein VV2_1340 1 None None None 27367872 Common - hypothetical protein VV2_1525 2 None None None 27366975 Common folE GTP cyclohydrolase I VV2_0543 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 27367360 Common - hypothetical protein VV2_0965 33 COG1359 COG1359, Uncharacterized conserved protein Function unknown 27367981 Common - hypothetical protein VV2_1640 3 None None None 27366800 Common - FOG: TPR repeat protein VV2_0359 11 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 27367496 Common - Arylsulfatase A VV2_1108 85 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 27367029 Common - Predicted dehydrogenase VV2_0600 82 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 27368023 Common - Membrane protein VV2_1684 130 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 27367556 Common - hypothetical protein VV2_1176 2 None None None 27367590 Pathogen - hypothetical protein VV2_1210 2 None None None 27367815 Common - GGDEF domain containing protein VV2_1462 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367810 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_1456 114 COG2962 RarD, Predicted permeases General function prediction only 27367436 Common - Glutaredoxin VV2_1045 122 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 27367320 Common - Predicted amidohydrolase VV2_0920 195 COG0388 COG0388, Predicted amidohydrolase General function prediction only 27367484 Common - UDP-glucose 4-epimerase VV2_1095 230 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 27366809 Common - Formate/nitrite family of transporter VV2_0368 94 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 27367329 Common - Signal transduction histidine kinase VV2_0931 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27367621 Common - Uncharacterized protein SCO1/SenC/PrrC VV2_1241 93 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 27367500 Common - Transcriptional regulator VV2_1112 163 COG1522 Lrp, Transcriptional regulators Transcription 27366483 Pathogen - hypothetical protein VV2_0021 1 None None None 27366996 Common - Heme/copper-type cytochrome/quinol oxidase, subunit 1 VV2_0567 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 27367679 Common - Na+-driven multidrug efflux pump VV2_1306 176 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 27367431 Common - hypothetical protein VV2_1040 5 None None None 27367045 Common - Predicted SpoU class rRNA methylase VV2_0617 23 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 27367716 Common - Autotransporter adhesin VV2_1346 9 None None None 27367201 Common - Predicted ATP-dependent protease VV2_0792 91 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 27367452 Common - PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities VV2_1062 232 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 27366930 Common - Acyl-CoA dehydrogenase VV2_0496 169 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 27367742 Common - cAMP-binding protein VV2_1376 7 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 27367674 Common - Beta-glucanase/Beta-glucan synthetase VV2_1300 49 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 27367469 Common - Transcriptional regulator of sugar metabolism VV2_1079 110 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 27367190 Common - Response regulator VV2_0779 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 27366756 Common - Response regulator VV2_0313 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 27366657 Common - hypothetical protein VV2_0202 14 None None None 27367507 Common - Signal transduction histidine kinase regulating C4-dicarboxylate transport system VV2_1123 220 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 27366915 Pathogen - Peptide chain release factor 1 VV2_0481 3 None None None 27366857 Common - Polyribonucleotide nucleotidyltransferase VV2_0420 27 None None None 27367923 Pathogen - hypothetical protein VV2_1577 2 None None None 27366824 Common - Putative GTPase VV2_0385 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 27367858 Common - Response regulator VieA VV2_1511 167 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 27366625 Common - Permease of the major facilitator superfamily VV2_0169 185 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 27367896 Common - Regulatory P domain of the subtilisin-like proprotein convertase VV2_1550 8 COG4935 COG4935, Regulatory P domain of the subtilisin-like proprotein convertases and other proteases Posttranslational modification, protein turnover, chaperones 27367903 Common - ABC-type phosphate transport system, permease component VV2_1557 226 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 27366558 Common - Predicted lipase VV2_0101 8 COG3675 COG3675, Predicted lipase Lipid metabolism 27366488 Pathogen - hypothetical protein VV2_0026 1 None None None 27367722 Common - Phosphotransferase system fructose-specific component IIB VV2_1352 68 COG1445 FrwB, Phosphotransferase system fructose-specific component IIB Carbohydrate transport and metabolism 27366978 Pathogen - hypothetical protein VV2_0546 1 None None None 27368019 Common - Exopolyphosphatase-related protein VV2_1679 12 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 27366928 Common - Acetyl-CoA acetyltransferase VV2_0494 170 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 27366783 Common - Membrane-fusion protein VV2_0341 137 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 27366522 Common rbsC ribose ABC transporter permease protein VV2_0063 123 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 27367883 Common - GTPase VV2_1536 11 None None None 27368004 Common - 4-aminobutyrate aminotransferase VV2_1663 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 27366939 Common - Transcriptional regulator VV2_0506 96 COG1309 AcrR, Transcriptional regulator Transcription 27366852 Common - Succinyl-CoA synthetase, alpha subunit VV2_0414 21 None None None 27366589 Common - Decaheme cytochrome c related protein VV2_0133 7 None None None 27366724 Common - Outer membrane receptor protein VV2_0276 121 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 27366498 Common - Amino acid permease VV2_0037 33 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 27366983 Common - transaldolase B VV2_0552 184 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 27367116 Common - hypothetical protein VV2_0697 17 COG5476 COG5476, Uncharacterized conserved protein Function unknown 27367043 Common - Histone acetyltransferase HPA2 VV2_0615 29 COG0456 RimI, Acetyltransferases General function prediction only 27367197 Common - DNA gyrase inhibitor VV2_0787 154 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27366650 Common - Membrane-fusion protein VV2_0194 149 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 27367347 Common - hypothetical protein VV2_0952 20 None None None 27367846 Common - hypothetical protein VV2_1496 2 None None None 27367566 Common - Transcriptional regulator VV2_1186 78 COG0583 LysR, Transcriptional regulator Transcription 27366679 Common - Superfamily II DNA and RNA helicase VV2_0227 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 27367051 Pathogen - ATPase involved in DNA repair VV2_0624 1 None None None 27367098 Common - Predicted amino acid racemase VV2_0675 16 COG3457 COG3457, Predicted amino acid racemase Amino acid transport and metabolism 27367515 Common - isoaspartyl dipeptidase VV2_1131 31 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 27367494 Common - Arylsulfatase A VV2_1106 82 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 27367637 Pathogen - hypothetical protein VV2_1260 1 None None None 27366605 Common - Arylsulfatase A VV2_0149 77 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 27367480 Common - hypothetical protein VV2_1091 4 None None None 27367751 Common - Outer membrane protein/protective antigen OMA87 VV2_1386 20 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 27366865 Common - hypothetical protein VV2_0428 65 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 27367945 Common - AraC-type DNA-binding domain-containing protein VV2_1602 3 None None None 27367009 Common - Outer membrane protein VV2_0580 34 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 27367104 Common - Transcriptional regulator VV2_0683 170 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 27367280 Common - Predicted epimerase VV2_0875 120 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 27367729 Pathogen - hypothetical protein VV2_1359 1 None None None 27367962 Common - Parvulin-like peptidyl-prolyl isomerase VV2_1620 134 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 27366961 Common - Methyl-accepting chemotaxis protein VV2_0528 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367828 Common - Uncharacterized iron-regulated membrane protein VV2_1476 62 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 27367837 Common tdh L-threonine 3-dehydrogenase VV2_1485 207 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 27367038 Common - Acetyltransferase VV2_0610 145 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 27366512 Common - Cytochrome c553 VV2_0052 59 COG2863 COG2863, Cytochrome c553 Energy production and conversion 27366708 Common - Predicted membrane protein VV2_0259 40 COG3647 COG3647, Predicted membrane protein Function unknown 27367020 Common - Translation initiation factor 2 VV2_0591 58 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 27367081 Common - hypothetical protein VV2_0656 4 None None None 27367367 Common - Transglutaminase-like enzyme VV2_0972 11 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 27366941 Common - Glutathione S-transferase VV2_0508 86 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 27366904 Common - adenosine deaminase VV2_0468 110 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 27367997 Common - AraC-type DNA-binding domain-containing protein VV2_1656 102 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27366883 Common - Serine/threonine protein kinase VV2_0446 143 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 27366471 Common - Regulatory P domain of the subtilisin-like proprotein convertase VV2_0008 10 COG4935 COG4935, Regulatory P domain of the subtilisin-like proprotein convertases and other proteases Posttranslational modification, protein turnover, chaperones 27367471 Common - Phosphotransferase system mannitol/fructose-specific IIA domain VV2_1081 49 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 27367417 Common - Transcriptional regulator of sugar metabolism VV2_1026 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 27366722 Pathogen - hypothetical protein VV2_0274 1 None None None 27367158 Common - Preprotein translocase subunit SecD VV2_0744 201 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 27366923 Common - 3-hydroxyisobutyrate dehydrogenase VV2_0489 180 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 27367573 Common - Response regulator of the LytR/AlgR family VV2_1193 217 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 27367261 Common - Amino acid permease VV2_0855 31 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 27367011 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_0582 109 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 27367598 Common - hypothetical protein VV2_1218 1 None None None 27367375 Common - FOG: CheY-like receiver VV2_0980 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27367337 Common - FOG: GGDEF domain VV2_0940 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367445 Pathogen - hypothetical protein VV2_1054 1 None None None 27367308 Common - Molybdenum cofactor biosynthesis enzyme VV2_0908 12 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 27367419 Common - AraC-type DNA-binding domain-containing protein VV2_1028 152 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27367520 Common - Acetyltransferase VV2_1136 192 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 27367127 Common - hypothetical protein VV2_0709 2 None None None 27367581 Common - hypothetical protein VV2_1201 4 None None None 27367292 Common - Cytochrome b VV2_0890 28 COG3658 COG3658, Cytochrome b Energy production and conversion 27367203 Common - ABC-type uncharacterized transport system, duplicated ATPase component VV2_0794 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 27367805 Common - hypothetical protein VV2_1451 13 None None None 27367840 Pathogen - hypothetical protein VV2_1488 2 None None None 27367511 Common - FOG: EAL domain protein VV2_1127 157 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 27367557 Common - ABC-type oligopeptide transport system, ATPase component VV2_1177 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 27367725 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_1355 59 None None None 27367817 Common - hypothetical protein VV2_1464 104 COG0393 COG0393, Uncharacterized conserved protein Function unknown 27367429 Common - Peptide methionine sulfoxide reductase VV2_1038 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 27366717 Common - Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component VV2_0268 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 27366690 Common - hypothetical protein VV2_0240 2 None None None 27367874 Common - Predicted acetyltransferase VV2_1527 23 COG2388 COG2388, Predicted acetyltransferase General function prediction only 27367170 Common - hypothetical protein VV2_0756 41 COG3132 COG3132, Uncharacterized protein conserved in bacteria Function unknown 27367752 Common - hypothetical protein VV2_1387 9 None None None 27366880 Common - hypothetical protein VV2_0443 49 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 27366712 Common - Predicted ATPase of the ABC class VV2_0263 26 COG3044 COG3044, Predicted ATPase of the ABC class General function prediction only 27367588 Common - 3-methyladenine DNA glycosylase VV2_1208 122 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 27366970 Pathogen - hypothetical protein VV2_0537 1 None None None 27366503 Common - Glutamate decarboxylase VV2_0043 89 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 27367089 Pathogen - Cysteinyl-tRNA synthetase VV2_0664 1 None None None 27367639 Common - Methyl-accepting chemotaxis protein VV2_1262 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367248 Common - ABC-type enterochelin transport system, periplasmic component VV2_0842 74 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 27367425 Common - Dihydrofolate reductase VV2_1034 74 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 27367898 Common - hypothetical protein VV2_1552 8 None None None 161501860 Common - putative L-ascorbate 6-phosphate lactonase VV2_1078 41 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 27366699 Common - Zn-dependent protease VV2_0250 25 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 27367301 Common - hypothetical protein VV2_0900 13 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 27367109 Common - ABC-type sulfate/molybdate transport system, ATPase component VV2_0688 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 27367328 Common - hypothetical protein VV2_0930 27 COG3915 COG3915, Uncharacterized protein conserved in bacteria Function unknown 27367355 Common - hypothetical protein VV2_0960 19 COG3110 COG3110, Uncharacterized protein conserved in bacteria Function unknown 27366765 Common - Response regulator VV2_0322 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 27367730 Common - NADPH-dependent glutamate synthase beta chain VV2_1360 235 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 27367483 Common - galactose-1-phosphate uridylyltransferase VV2_1094 79 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 27367857 Common - Response regulator VV2_1510 128 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 27366840 Common - Methyl-accepting chemotaxis protein VV2_0401 157 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367256 Common - Outer membrane protein VV2_0850 51 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 27367019 Common - 3-carboxymuconate cyclase VV2_0590 54 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 27366566 Pathogen - hypothetical protein VV2_0109 1 None None None 27367922 Common - Glycosyltransferase VV2_1576 56 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 27367782 Common - Transcriptional regulator VV2_1419 153 COG0583 LysR, Transcriptional regulator Transcription 27367739 Common - Nicotinamide mononucleotide transporter VV2_1372 57 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 27367761 Common - hypothetical protein VV2_1397 8 None None None 27367649 Common - Transcriptional regulator VV2_1273 95 COG0583 LysR, Transcriptional regulator Transcription 27366538 Common - DNA repair exonuclease VV2_0079 107 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 27367223 Common artP arginine transporter ATP-binding subunit VV2_0815 249 COG4161 ArtP, ABC-type arginine transport system, ATPase component Amino acid transport and metabolism 27367400 Common - Membrane-fusion protein VV2_1008 167 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 27366741 Pathogen - hypothetical protein VV2_0295 1 None None None 27366673 Common - hypothetical protein VV2_0219 50 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 27367548 Common - Chemotaxis signal transduction protein VV2_1167 125 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 27366490 Common - Cation/multidrug efflux pump VV2_0028 42 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 27366481 Common - Alcohol dehydrogenase, class IV VV2_0019 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 27366912 Common alr alanine racemase VV2_0478 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 27366624 Common - FOG: Transposase VV2_0168 28 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 27367666 Common - ABC-type dipeptide transport system, periplasmic component VV2_1291 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 27366685 Common - Transcriptional regulator VV2_0234 189 COG0583 LysR, Transcriptional regulator Transcription 27367930 Common malE maltose ABC transporter periplasmic protein VV2_1585 96 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 27367536 Common - hypothetical protein VV2_1153 6 None None None 27367430 Common - hypothetical protein VV2_1039 30 None None None 27366633 Common - Predicted amidohydrolase VV2_0177 70 COG0388 COG0388, Predicted amidohydrolase General function prediction only 27367942 Common nadE NAD synthetase VV2_1599 195 COG0171 NadE, NAD synthase Coenzyme metabolism 27367733 Common - purine nucleoside phosphorylase VV2_1364 147 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 27367992 Common - Acetyltransferase VV2_1651 175 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 27367386 Common - Response regulator VV2_0991 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 27366977 Common - molybdopterin biosynthesis protein MoeB VV2_0545 222 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 27367315 Common - Transcriptional regulator VV2_0915 124 COG1414 IclR, Transcriptional regulator Transcription 27366586 Common - hypothetical protein VV2_0130 100 COG1262 COG1262, Uncharacterized conserved protein Function unknown 27366862 Common - Predicted nucleotidyltransferase VV2_0425 70 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 27366770 Common modC molybdate transporter ATP-binding protein VV2_0327 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 27367915 Common - DNA-binding HTH domain-containing protein VV2_1569 152 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 27367961 Common - Chemotaxis protein CheV, putative VV2_1619 126 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 27366848 Common - hypothetical protein VV2_0410 3 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 27367651 Common - Uncharacterized membrane-associated protein VV2_1275 82 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 27367952 Common - ABC-type Fe3+-siderophore transport system, permease component VV2_1610 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 27366779 Common nrdG anaerobic ribonucleotide reductase-activating protein VV2_0336 60 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 27367744 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_1378 2 None None None 27366578 Common helD DNA helicase IV VV2_0122 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 27367274 Common - NAD-dependent aldehyde dehydrogenase VV2_0869 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 27367323 Common - Histone acetyltransferase HPA2 VV2_0924 3 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 27367439 Common - hypothetical protein VV2_1048 12 None None None 27367913 Common - Methyl-accepting chemotaxis protein VV2_1567 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366550 Common - Flp pilus assembly protein TadD VV2_0092 14 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 27367284 Common - Long-chain fatty acid transport protein VV2_0881 70 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 27366988 Common - phospho-2-dehydro-3-heoxyheptonate aldolase VV2_0558 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 27367907 Common - hypothetical protein VV2_1561 25 None None None 27367063 Common - hypothetical protein VV2_0637 13 None None None 27367133 Common - FOG: PAS/PAC domain VV2_0715 17 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 27366477 Common - Threonine aldolase VV2_0014 74 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 27366604 Common - acetate kinase VV2_0148 162 COG0282 ackA, Acetate kinase Energy production and conversion 27367789 Common - hypothetical protein VV2_1427 2 None None None 27367834 Common - Regulatory P domain of the subtilisin-like proprotein convertase VV2_1482 138 COG4935 COG4935, Regulatory P domain of the subtilisin-like proprotein convertases and other proteases Posttranslational modification, protein turnover, chaperones 27366872 Common - hypothetical protein VV2_0435 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 27367855 Common - Putative two-component response regulator VV2_1508 170 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 27367772 Common - Glycosidase VV2_1408 162 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 27367724 Common - Transcriptional regulator VV2_1354 197 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 27367849 Common - Outer membrane protein V VV2_1501 14 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 27367050 Pathogen - ATPase involved in DNA repair VV2_0623 5 None None None 27367143 Common - hypothetical protein VV2_0727 9 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 27366524 Common - ribokinase VV2_0065 164 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 27367194 Common - Permease of the major facilitator superfamily VV2_0783 4 None None None 27366495 Pathogen - Signal recognition particle GTPase VV2_0033 1 None None None 27367010 Common - FOG: EAL domain protein VV2_0581 171 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 27367331 Common - Phospholipid-binding protein VV2_0933 120 COG1881 COG1881, Phospholipid-binding protein General function prediction only 27367238 Common - Non-ribosomal peptide synthetase modules VV2_0831 217 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 27366795 Common - Na+-driven multidrug efflux pump VV2_0353 172 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 27367169 Pathogen - Predicted endonuclease containing a URI domain VV2_0755 1 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 27367033 Common - Transcriptional regulator VV2_0605 84 COG1846 MarR, Transcriptional regulators Transcription 27366986 Common - Predicted signal transduction protein VV2_0556 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 27367027 Common - ABC-type multidrug transport system, ATPase component VV2_0598 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 27368025 Common - transcriptional regulator BetI VV2_1686 51 COG1309 AcrR, Transcriptional regulator Transcription 27367373 Common - hypothetical protein VV2_0978 35 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 27367121 Common - Phosphatidylserine/phosphatidylglycerophosphate/cardiolipin synthase VV2_0702 126 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 27367078 Pathogen - GTPase VV2_0652 1 None None None 27367561 Common - ABC-type amino acid transport/signal transduction system VV2_1181 7 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 27367459 Common - Mannitol-1-phosphate/altronate dehydrogenase VV2_1069 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 27367187 Common - Transcriptional regulator VV2_0776 194 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 27367093 Common - hypothetical protein VV2_0669 39 COG3367 COG3367, Uncharacterized conserved protein Function unknown 27367964 Common - Glycosidase VV2_1622 37 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 27367568 Common - ABC-type antimicrobial peptide transport system, ATPase component VV2_1188 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 27367990 Common - bifunctional methionine sulfoxide reductase A/B protein VV2_1649 206 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 27367113 Common - Transposase VV2_0693 12 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 27367041 Common - hypothetical protein VV2_0613 10 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 27367307 Common - FOG: Ankyrin repeat VV2_0907 35 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 27366543 Common - hypothetical protein VV2_0085 2 None None None 27366643 Common - glycine cleavage system protein H VV2_0187 188 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 27366622 Common - Permease of the major facilitator superfamily VV2_0166 145 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 27367957 Common - coproporphyrinogen III oxidase VV2_1615 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 27366938 Common - Ca2+/Na+ antiporter VV2_0505 129 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 27367882 Common - Multidrug resistance efflux pump VV2_1535 124 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27367343 Pathogen - hypothetical protein VV2_0947 1 None None None 27367876 Common - hypothetical protein VV2_1529 142 COG4946 COG4946, Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system Function unknown 27367155 Common - acetyl-CoA acetyltransferase VV2_0741 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 27366855 Pathogen - Predicted transcriptional regulator VV2_0418 1 None None None 27366738 Common - hypothetical protein VV2_0292 2 None None None 27367823 Common - Soluble cytochrome b562 VV2_1470 6 COG3783 CybC, Soluble cytochrome b562 Energy production and conversion 27367414 Common - Predicted phosphosugar isomerase VV2_1023 33 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 27366519 Common - Putative threonine efflux protein VV2_0059 100 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 27367890 Common - Deoxyribodipyrimidine photolyase VV2_1543 133 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 27366791 Common - 3-oxoacyl-(acyl carrier protein) synthase III VV2_0349 222 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 27367948 Pathogen - hypothetical protein VV2_1605 2 None None None 27366785 Common - Predicted transporter component VV2_0343 69 COG2391 COG2391, Predicted transporter component General function prediction only 27367592 Common - hypothetical protein VV2_1212 53 COG3791 COG3791, Uncharacterized conserved protein Function unknown 27366726 Common - Histone acetyltransferase HPA2 VV2_0278 151 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 27366465 Common - ABC-type proline/glycine betaine transport system, ATPase component VV2_0002 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 27368013 Common - Glycine/D-amino acid oxidase VV2_1673 97 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 27366850 Common - hypothetical protein VV2_0412 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 27367498 Common - hypothetical protein VV2_1110 12 None None None 27367599 Common - hypothetical protein VV2_1219 52 COG3123 COG3123, Uncharacterized protein conserved in bacteria Function unknown 27366782 Common - Cation/multidrug efflux pump VV2_0340 178 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 27368006 Common - ABC-type Fe3+ transport system, periplasmic component VV2_1665 107 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 27367398 Common - ABC-type antimicrobial peptide transport system, permease component VV2_1006 163 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 27366802 Common - Biopolymer transport protein VV2_0361 54 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 27367685 Common - hypothetical protein VV2_1312 2 COG2433 COG2433, Uncharacterized conserved protein Function unknown 27367486 Common - hypothetical protein VV2_1097 13 None None None 27367749 Common - Na+/H+-dicarboxylate symporter VV2_1383 165 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 27366470 Common - hypothetical protein VV2_0007 21 None None None 27366889 Common - hypothetical protein VV2_0452 15 None None None 27367139 Common - Anaerobic dehydrogenase, typically selenocysteine-containing VV2_0721 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 27367466 Common - glutaredoxin 2 VV2_1076 18 COG2999 GrxB, Glutaredoxin 2 Posttranslational modification, protein turnover, chaperones 27367096 Common - Na+/H+ antiporter VV2_0672 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 27367180 Common - Adenylosuccinate synthase VV2_0768 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 27366614 Common - FOG: TPR repeat protein VV2_0158 56 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 27366648 Common - Transcriptional regulator VV2_0192 29 COG1309 AcrR, Transcriptional regulator Transcription 27366555 Common - Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase component VV2_0097 2 None None None 27366803 Common - Biopolymer transport protein VV2_0362 72 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 27367102 Common - hypothetical protein VV2_0681 5 None None None 27366706 Common - Transcriptional regulator VV2_0257 186 COG0583 LysR, Transcriptional regulator Transcription 27367177 Common - glyceraldehyde-3-phosphate dehydrogenase VV2_0764 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 27366958 Common - Thiol-disulfide isomerase VV2_0525 18 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 27367880 Common - ABC-type cobalt transport system, ATPase component VV2_1533 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 27367450 Common - Transcriptional regulator VV2_1060 127 COG1609 PurR, Transcriptional regulators Transcription 27367390 Common - Permease of the major facilitator superfamily VV2_0995 11 None None None 27367839 Pathogen - hypothetical protein VV2_1487 1 None None None 27366660 Common - FOG: EAL domain protein VV2_0205 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 161501862 Common ulaA ascorbate-specific PTS system enzyme IIC VV2_0862 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 27367410 Common - Phosphotransferase system, mannose/fructose-specific component IIA VV2_1019 83 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 27367120 Common - Beta-lactamase class C VV2_0701 116 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 27366710 Common - DnaJ-class molecular chaperone VV2_0261 15 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 27367427 Common - FOG: TPR repeat protein, SEL1 subfamily VV2_1036 107 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 27366505 Common - Predicted permease VV2_0045 98 COG2962 RarD, Predicted permeases General function prediction only 27366972 Common - chloride channel protein VV2_0540 157 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 27366526 Common - hypothetical protein VV2_0067 2 None None None 27366832 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component VV2_0393 80 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 27366767 Common - hypothetical protein VV2_0324 2 None None None 27366815 Common - Acyl dehydratase VV2_0375 61 COG2030 MaoC, Acyl dehydratase Lipid metabolism 27368001 Common - Transcriptional regulator VV2_1660 223 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 27367357 Common - Flavodoxin reductase family 1 protein VV2_0962 103 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 27366515 Common - MoxR-like ATPase VV2_0055 83 COG0714 COG0714, MoxR-like ATPases General function prediction only 27367164 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_0750 42 COG2510 COG2510, Predicted membrane protein Function unknown 27367732 Common - Transcriptional regulator VV2_1363 16 COG0583 LysR, Transcriptional regulator Transcription 27366606 Common - Transcriptional regulator VV2_0150 147 COG0583 LysR, Transcriptional regulator Transcription 27366731 Common - S-adenosylhomocysteine hydrolase VV2_0283 2 None None None 27367218 Common - hypothetical protein VV2_0810 2 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 27367701 Common - Alpha-galactosidase VV2_1330 43 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 27367630 Common - Methyl-accepting chemotaxis protein VV2_1253 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367689 Common - Pseudouridylate synthase, 23S RNA-specific VV2_1318 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 27367443 Common - Transcriptional regulator VV2_1052 145 COG1522 Lrp, Transcriptional regulators Transcription 27367447 Pathogen - hypothetical protein VV2_1056 1 None None None 27367924 Common - Glycosyltransferase VV2_1578 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 27366697 Common - Hydrolases of the alpha/beta superfamily VV2_0248 9 None None None 27367276 Common - FOG: GGDEF domain VV2_0871 194 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367629 Common - glycogen branching enzyme VV2_1252 147 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 27367179 Common - Transcriptional regulator VV2_0767 188 COG0583 LysR, Transcriptional regulator Transcription 27367290 Common - Transcriptional regulator VV2_0888 152 COG0583 LysR, Transcriptional regulator Transcription 27366963 Common - Membrane-fusion protein VV2_0530 147 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 27366715 Common - Lysophospholipase L1 VV2_0266 100 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 27367644 Common - HD-GYP domain VV2_1268 121 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 27368020 Common - NTP pyrophosphohydrolase VV2_1680 15 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 27367905 Common - ABC-type phosphate transport system, ATPase component VV2_1559 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 27367527 Common - Outer membrane protein VV2_1143 23 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 27367211 Common - Predicted transcriptional regulator VV2_0802 16 None None None 27367463 Common - hypothetical protein VV2_1073 17 None None None 27366979 Common - Rhodanese-related sulfurtransferase VV2_0547 146 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 27367819 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_1466 14 None None None 27367205 Common - Transcriptional regulator VV2_0796 152 COG0583 LysR, Transcriptional regulator Transcription 27367333 Common - hypothetical protein VV2_0935 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 27366616 Common - Transcriptional regulator VV2_0160 146 COG0583 LysR, Transcriptional regulator Transcription 27367544 Common - Chemotaxis protein VV2_1162 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 27367298 Pathogen - hypothetical protein VV2_0897 1 COG2433 COG2433, Uncharacterized conserved protein Function unknown 27367918 Common - ABC-type protease/lipase transport system, ATPase and permease component VV2_1572 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 27367559 Common - hypothetical protein VV2_1179 2 None None None 27367477 Common - hypothetical protein VV2_1087 15 COG4874 COG4874, Uncharacterized protein conserved in bacteria containing a pentein-type domain Function unknown 27366728 Common ddl D-alanyl-alanine synthetase A VV2_0280 214 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 27367433 Common - Methyl-accepting chemotaxis protein VV2_1042 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366653 Common - Phosphotransferase system, fructose-specific IIC component VV2_0198 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 27367950 Common - Transcriptional regulator LuxT VV2_1607 3 COG1309 AcrR, Transcriptional regulator Transcription 27366891 Common phhB pterin-4-alpha-carbinolamine dehydratase VV2_0454 71 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 27366833 Common - Response regulator VV2_0394 44 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 27367031 Common - Predicted Zn-dependent hydrolase of the beta-lactamase fold VV2_0602 87 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 27367842 Common - hypothetical protein VV2_1491 96 COG1262 COG1262, Uncharacterized conserved protein Function unknown 27367795 Common - phosphomethylpyrimidine kinase VV2_1433 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 27366860 Common - hypothetical protein VV2_0423 2 None None None 27367513 Common - Multimeric flavodoxin WrbA VV2_1129 115 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 27367183 Common - Transcriptional regulator VV2_0772 128 COG0583 LysR, Transcriptional regulator Transcription 27366843 Common - Cytolysin VV2_0404 3 None None None 27367501 Common - Na+/proline symporter VV2_1116 155 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 27366568 Common - ABC-type enterochelin transport system, permease component VV2_0111 172 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 27366874 Common - hypothetical protein VV2_0437 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 27367695 Common mglC beta-methylgalactoside transporter inner membrane component VV2_1324 132 COG4211 MglC, ABC-type glucose/galactose transport system, permease component Carbohydrate transport and metabolism 27366584 Common - Type IIA topoisomerase, B subunit VV2_0128 15 None None None 27366611 Common - hypothetical protein VV2_0155 101 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 27367658 Common - Transcriptional regulator VV2_1282 130 COG1609 PurR, Transcriptional regulators Transcription 27367264 Common - Predicted ferric reductase VV2_0858 68 COG4097 COG4097, Predicted ferric reductase Inorganic ion transport and metabolism 27366536 Common - FOG: CheY-like receiver VV2_0077 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27367225 Common - arginine transporter permease subunit ArtQ VV2_0817 175 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 27366869 Common - hypothetical protein VV2_0432 48 COG3519 COG3519, Uncharacterized protein conserved in bacteria Function unknown 27367233 Common - ABC-type amino acid transport/signal transduction system VV2_0826 86 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 27366561 Common - Response regulator of citrate/malate metabolism VV2_0104 190 COG4565 CitB, Response regulator of citrate/malate metabolism Transcription / Signal transduction mechanisms 27367932 Common malG maltose transporter permease VV2_1587 179 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 27366464 Common - ABC-type proline/glycine betaine transport system, permease component VV2_0001 215 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 27367117 Common - D-glutamate deacylase VV2_0698 70 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 27367826 Common - Catalase VV2_1473 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 27367735 Common - hypothetical protein VV2_1367 13 None None None 27367167 Common - ABC-type sugar transport system, periplasmic component VV2_0753 27 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 27366576 Pathogen - hypothetical protein VV2_0120 1 None None None 27367614 Pathogen - hypothetical protein VV2_1234 1 None None None 27367605 Common - FOG: GGDEF domain VV2_1225 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367550 Common - FOG: CheY-like receiver VV2_1169 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 27367684 Common - Histone acetyltransferase HPA2 VV2_1311 25 COG3153 COG3153, Predicted acetyltransferase General function prediction only 27367384 Common - Alkyl sulfatase VV2_0989 44 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 27367522 Common - hypothetical protein VV2_1138 11 COG3904 COG3904, Predicted periplasmic protein Function unknown 27367750 Common - hypothetical protein VV2_1385 6 None None None 27367664 Common - Transcriptional regulator VV2_1289 130 COG1609 PurR, Transcriptional regulators Transcription 27367563 Common - hypothetical protein VV2_1183 2 None None None 27367926 Common - Periplasmic protein involved in polysaccharide export VV2_1580 90 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 27367091 Pathogen - hypothetical protein VV2_0666 1 None None None 27367619 Common - ribosome-associated GTPase VV2_1239 163 COG1162 COG1162, Predicted GTPases General function prediction only 27367371 Common - Transcriptional antiterminator VV2_0976 5 COG4568 Rof, Transcriptional antiterminator Transcription 27367690 Common - FOG: GGDEF domain VV2_1319 184 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367189 Common - Signal transduction histidine kinase VV2_0778 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27367464 Common - Transcriptional regulator VV2_1074 156 COG0583 LysR, Transcriptional regulator Transcription 27367534 Common - hypothetical protein VV2_1150 31 COG4807 COG4807, Uncharacterized protein conserved in bacteria Function unknown 27367594 Common - Fucose 4-O-acetylase VV2_1214 3 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 27366907 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 VV2_0471 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 27367071 Common - mating pair stabilization protein VV2_0645 25 None None None 27367338 Common - Histone acetyltransferase HPA2 VV2_0941 58 COG0456 RimI, Acetyltransferases General function prediction only 27366946 Common - regulatory protein UhpC VV2_0513 144 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 27367525 Common murQ N-acetylmuramic acid-6-phosphate etherase VV2_1141 86 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 27366641 Common - Superfamily I DNA and RNA helicase VV2_0185 10 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 27367607 Common - Maltoporin VV2_1227 15 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 27367140 Common - Nitrate reductase cytochrome c-type subunit VV2_0722 41 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 27367909 Common - Uncharacterized protein containing a von Willebrand factor type A (vWA) domain VV2_1563 83 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 27366973 Common - Tellurite resistance protein VV2_0541 37 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 27367130 Common - guanosine 5'-monophosphate oxidoreductase VV2_0712 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 27367853 Common - hypothetical protein VV2_1505 4 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 27367111 Pathogen - hypothetical protein VV2_0691 1 None None None 27367362 Common - Predicted hydrolase/acyltransferase VV2_0967 47 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 27367100 Pathogen - Ribosomal protein S2 VV2_0678 1 None None None 27366954 Common - hypothetical protein VV2_0521 2 None None None 27367379 Common - TRAP-type uncharacterized transport system, fused permease component VV2_0984 115 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 27366743 Common - Outer membrane receptor protein VV2_0298 2 None None None 27366760 Common pntA NAD(P) transhydrogenase subunit alpha VV2_0317 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 27366475 Common glpC sn-glycerol-3-phosphate dehydrogenase subunit C VV2_0012 180 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 27367006 Common - Predicted redox protein, regulator of disulfide bond formation VV2_0577 89 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 27367409 Common - N-acetylglucosamine-6-phosphate deacetylase VV2_1018 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 27367107 Common - ABC-type sulfate transport system, permease component VV2_0686 221 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 27367395 Common - DNA polymerase III, alpha subunit VV2_1003 193 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 27367435 Common - Predicted membrane protein VV2_1044 20 COG3059 COG3059, Predicted membrane protein Function unknown 27366702 Common - Phosphotransferase system IIA component VV2_0253 4 None None None 27366704 Common - hypothetical protein VV2_0255 7 None None None 27367836 Common - 2-amino-3-ketobutyrate coenzyme A ligase VV2_1484 191 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 27367317 Common - DNA polymerase III, epsilon subunit VV2_0917 35 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 27367137 Common - nitrate/nitrite sensor protein NarQ VV2_0719 146 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 161501859 Common murP N-acetylmuramic acid phosphotransfer permease VV2_1142 43 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 27367341 Common - hypothetical protein VV2_0945 5 COG1433 COG1433, Uncharacterized conserved protein Function unknown 27367490 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease component VV2_1101 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 27366683 Common - hypothetical protein VV2_0231 115 COG2353 COG2353, Uncharacterized conserved protein Function unknown 27367231 Common - ABC-type amino acid transport/signal transduction systems VV2_0823 23 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 27367002 Common - Predicted branched-chain amino acid permease VV2_0573 105 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 27366887 Common - hypothetical protein VV2_0450 42 COG3530 COG3530, Uncharacterized protein conserved in bacteria Function unknown 27367788 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase VV2_1426 228 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 27366797 Common - hypothetical protein VV2_0355 8 None None None 27367889 Common - Transcriptional regulator, MerR family VV2_1542 53 COG0789 SoxR, Predicted transcriptional regulators Transcription 27366935 Common - Peroxiredoxin VV2_0501 218 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 27367025 Common - Transcriptional regulator VV2_0596 91 COG1737 RpiR, Transcriptional regulators Transcription 27367271 Common - hypothetical protein VV2_0865 2 None None None 27367289 Common - FOG: TPR repeat protein VV2_0887 11 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 27366669 Common glgC glucose-1-phosphate adenylyltransferase VV2_0214 194 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 27366998 Common - Phosphomannomutase VV2_0569 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 27367727 Common - Phosphotransferase system mannitol VV2_1357 73 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 27366631 Common - hypothetical protein VV2_0175 7 None None None 27367663 Common - ABC-type sugar transport system, ATPase component VV2_1288 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 27367675 Common - Maltoporin VV2_1301 24 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 27366842 Pathogen - Membrane-fusion protein VV2_0403 1 None None None 27367711 Pathogen - Mg-dependent DNase VV2_1341 1 None None None 27367811 Common - Malate/lactate dehydrogenase VV2_1457 153 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 27367069 Pathogen - hypothetical protein VV2_0643 1 None None None 27367768 Common - hypothetical protein VV2_1404 6 None None None 27367392 Common - hypothetical protein VV2_0997 24 None None None 27366553 Common - Flp pilus assembly protein TadG VV2_0095 3 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 27367775 Common - Predicted membrane-associated metal-dependent hydrolase VV2_1411 61 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 27366805 Common - Chromosome segregation ATPase VV2_0364 18 None None None 27367955 Common - Biopolymer transport protein VV2_1613 3 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 27368022 Common - Chitinase, putative VV2_1682 42 None None None 27366487 Common - Transcriptional regulator, effector-binding domain/component VV2_0025 23 None None None 27366920 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component VV2_0486 16 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 27366910 Common - Dehydrogenase VV2_0476 114 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 27367504 Common - AraC-type DNA-binding domain-containing protein VV2_1119 137 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27367878 Common - Permease of the major facilitator superfamily VV2_1531 18 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 27367987 Common - Predicted transcriptional regulator VV2_1646 4 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 27367457 Common - TRAP-type C4-dicarboxylate transport system, small permease component VV2_1067 47 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 27368008 Pathogen - hypothetical protein VV2_1668 1 None None None 27367821 Common - 2-oxoglutarate dehydrogenase complex, dehydrogenase component VV2_1468 5 COG3832 COG3832, Uncharacterized conserved protein Function unknown 27367023 Common - N-acyl-D-aspartate/D-glutamate deacylase VV2_0594 55 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 27368015 Common - hypothetical protein VV2_1675 12 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 27367383 Common - hypothetical protein VV2_0988 2 None None None 27367975 Common - Predicted phosphatase/phosphohexomutase VV2_1634 186 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 27367489 Common - ATPase component of various ABC-type transport system VV2_1100 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 27367017 Common - Predicted signal transduction protein VV2_0588 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 27366517 Common - hypothetical protein VV2_0057 40 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 27366951 Common - hypothetical protein VV2_0518 17 COG3036 COG3036, Uncharacterized protein conserved in bacteria Function unknown 27367967 Common - Predicted membrane protein VV2_1626 40 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 27367583 Common - hypothetical protein VV2_1203 7 COG3930 COG3930, Uncharacterized protein conserved in bacteria Function unknown 27367887 Common - purine nucleoside phosphorylase VV2_1540 94 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 27366919 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component VV2_0485 30 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 27366594 Common - FOG: EAL domain protein VV2_0138 203 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 27366793 Common - Permease of the major facilitator superfamily VV2_0351 115 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 27366787 Common - Rhodanese-related sulfurtransferase VV2_0345 40 None None None 27367892 Pathogen - Murein lipoprotein VV2_1545 1 None None None 27367192 Pathogen - hypothetical protein VV2_0781 1 None None None 27366580 Common - periplasmic sensory protein associated with the TorRS two-component regulatory system VV2_0124 14 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 27367576 Common - hypothetical protein VV2_1196 8 None None None 27366590 Common - Nitrate/TMAO reductase VV2_0134 36 None None None 27366597 Common - Predicted signal transduction protein VV2_0141 169 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 27368003 Common - Predicted phosphatase/phosphohexomutase VV2_1662 25 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 27366786 Common - Predicted transcriptional regulator VV2_0344 164 COG0640 ArsR, Predicted transcriptional regulators Transcription 27367072 Common - hypothetical protein VV2_0646 18 None None None 27367148 Common - TRAP-type C4-dicarboxylate transport system, periplasmic component VV2_0733 99 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 27367003 Common - Predicted membrane protein VV2_0574 19 COG4392 COG4392, Predicted membrane protein Function unknown 161501858 Common - hypothetical protein VV2_1184 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 27366755 Common - hypothetical protein VV2_0312 2 None None None 27366499 Common - Diadenosine tetraphosphatase VV2_0038 75 None None None 27366745 Common - hypothetical protein VV2_0301 2 None None None 27366588 Common - Cytochrome c553 VV2_0132 50 COG2863 COG2863, Cytochrome c553 Energy production and conversion 27366924 Common - Enoyl-CoA hydratase/carnithine racemase VV2_0490 131 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 27367420 Pathogen - Predicted choline kinase involved in LPS biosynthesis VV2_1029 3 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 27366789 Common - hypothetical protein VV2_0347 47 COG5267 COG5267, Uncharacterized protein conserved in bacteria Function unknown 27367671 Common - hypothetical protein VV2_1296 4 None None None 27366548 Common - Flp pilus assembly protein TadB VV2_0090 70 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 27366901 Common - Response regulator VV2_0465 124 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 27366583 Common - Fatty acid cis/trans isomerase VV2_0127 15 None None None 27367311 Common - hypothetical protein VV2_0911 22 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 27366528 Common - Fatty-acid desaturase VV2_0069 63 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 27367007 Common - Outer membrane protein VV2_0578 25 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 27367786 Common - Thiol-disulfide isomerase VV2_1424 69 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 27367455 Common - Transcriptional regulator VV2_1065 145 COG2186 FadR, Transcriptional regulators Transcription 27368018 Pathogen - hypothetical protein VV2_1678 1 COG1434 COG1434, Uncharacterized conserved protein Function unknown 27367769 Common - ABC-type amino acid transport/signal transduction systems VV2_1405 20 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 27366530 Common rbgA ribosomal biogenesis GTPase VV2_0071 110 COG1161 COG1161, Predicted GTPases General function prediction only 27367893 Common - ATP-dependent RNA helicase, DEAD box family VV2_1546 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 27367434 Pathogen - hypothetical protein VV2_1043 1 None None None 27366853 Common - Rhs family protein VV2_0415 46 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 27367612 Common - FOG: TPR repeat protein, SEL1 subfamily VV2_1232 88 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 27367134 Common - Response regulator VV2_0716 210 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 27366886 Common - Predicted DNA-binding protein VV2_0449 19 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 27367884 Common - GGDEF family protein VV2_1537 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367838 Pathogen - hypothetical protein VV2_1486 1 None None None 27366925 Common - enoyl-CoA hydratase VV2_0491 184 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 27367713 Common - anaerobic nitric oxide reductase flavorubredoxin VV2_1343 121 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 27367661 Common - ABC-type sugar transport system, permease component VV2_1286 162 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 27367267 Common - Phosphotransferase system, galactitol-specific IIB component VV2_0861 29 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 27367141 Common - Nitrate/TMAO reductase, membrane-bound tetraheme cytochrome c subunit VV2_0723 46 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 27367622 Common - hypothetical protein VV2_1242 2 None None None 27366984 Common - transketolase VV2_0553 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 27366513 Common - Threonine aldolase VV2_0053 94 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 27367016 Common - Transcriptional regulator VV2_0587 177 COG0583 LysR, Transcriptional regulator Transcription 27367048 Pathogen - hypothetical protein VV2_0620 1 None None None 27367553 Common - Predicted transcriptional regulator VV2_1172 18 COG1475 Spo0J, Predicted transcriptional regulators Transcription 27367097 Common - hypothetical protein VV2_0673 11 None None None 27367288 Common - Alkyl sulfatase VV2_0885 42 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 27367759 Common - Probable taurine catabolism dioxygenase VV2_1395 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 27367766 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_1402 55 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 27368027 Common - choline dehydrogenase VV2_1688 93 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 27367327 Common - Membrane-fusion protein VV2_0929 88 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 27366559 Common - Di- and tricarboxylate transporter VV2_0102 79 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 27366618 Common - hypothetical protein VV2_0162 95 COG1262 COG1262, Uncharacterized conserved protein Function unknown 27367394 Common - FOG: GGDEF domain VV2_1000 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367776 Common - Diacylglycerol kinase VV2_1412 58 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 27366808 Common - Uroporphyrinogen-III methylase VV2_0367 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 27367334 Common - Predicted transcriptional regulator VV2_0936 101 COG0789 SoxR, Predicted transcriptional regulators Transcription 27366491 Common - Cation/multidrug efflux pump VV2_0029 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 27367057 Pathogen - hypothetical protein VV2_0631 1 None None None 27367364 Pathogen - FOG: TPR repeat protein VV2_0969 1 None None None 27367777 Common - Signal transduction histidine kinase VV2_1413 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27367814 Common - Valyl-tRNA synthetase VV2_1461 3 None None None 27367441 Common - Alpha-galactosidase/6-phospho-beta-glucosidase VV2_1050 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 27367654 Common - Response regulator VV2_1278 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 27366903 Pathogen - hypothetical protein VV2_0467 1 None None None 27367030 Common - Transcriptional regulator VV2_0601 61 COG1309 AcrR, Transcriptional regulator Transcription 27367115 Pathogen - Transposase VV2_0695 8 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 27366942 Common - hypothetical protein VV2_0509 5 None None None 27367579 Common - hypothetical protein VV2_1199 8 None None None 27367198 Common codB cytosine permease VV2_0788 72 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 27367721 Common - Phosphotransferase system mannitol VV2_1351 12 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 27367014 Common - hypothetical protein VV2_0585 2 None None None 27367456 Common - TRAP-type C4-dicarboxylate transport system, periplasmic component VV2_1066 118 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 27366666 Common - Uncharacterized oxidoreductase VV2_0211 167 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 27366837 Common - Anaerobic dehydrogenase, typically selenocysteine-containing VV2_0398 190 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 27367529 Common - Fructose-2,6-bisphosphatase VV2_1145 39 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 27367682 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_1309 4 None None None 27367996 Common - nucleotidase VV2_1655 116 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 27367704 Common - rRNA methylase VV2_1334 200 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 27366955 Common - Glutaredoxin VV2_0522 22 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 27366474 Common - anaerobic glycerol-3-phosphate dehydrogenase subunit B VV2_0011 32 COG3075 GlpB, Anaerobic glycerol-3-phosphate dehydrogenase Amino acid transport and metabolism 27367103 Common - Transposase VV2_0682 6 None None None 27366511 Common - NAD-dependent aldehyde dehydrogenase VV2_0051 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 27367052 Common - hypothetical protein VV2_0625 2 None None None 27367090 Pathogen - hypothetical protein VV2_0665 1 None None None 27367191 Pathogen - hypothetical protein VV2_0780 1 None None None 27367260 Common tnaA tryptophanase VV2_0854 44 COG3033 TnaA, Tryptophanase Amino acid transport and metabolism 27366656 Common - DNA-binding transcriptional regulator FruR VV2_0201 123 COG1609 PurR, Transcriptional regulators Transcription 27367376 Common - Response regulator VV2_0981 224 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 27367479 Common - hypothetical protein VV2_1090 13 None None None 27367595 Common - Transcriptional regulator VV2_1215 39 COG1309 AcrR, Transcriptional regulator Transcription 27367080 Common - Integrase VV2_0655 35 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 27367691 Common - Cation/multidrug efflux pump VV2_1320 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 27367852 Pathogen - hypothetical protein VV2_1504 1 None None None 27366646 Common - Glycine cleavage system T protein VV2_0190 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 27367037 Common - Ribosome recycling factor VV2_0609 4 None None None 27367845 Common - hypothetical protein VV2_1495 3 None None None 27367126 Common - hypothetical protein VV2_0708 8 None None None 27367346 Pathogen - Translation initiation factor 1 VV2_0951 1 None None None 27366949 Common - FOG: GGDEF domain VV2_0516 181 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27366777 Common - aromatic amino acid aminotransferase VV2_0334 71 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 27367970 Common - hypothetical protein VV2_1629 15 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 27367539 Common - Predicted polymerase VV2_1157 37 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 27366714 Common - Uncharacterized paraquat-inducible protein B VV2_0265 25 COG3007 COG3007, Uncharacterized paraquat-inducible protein B Function unknown 27366506 Common - hypothetical protein VV2_0046 14 None None None 27367693 Common - Transcriptional regulator VV2_1322 61 COG1309 AcrR, Transcriptional regulator Transcription 27366768 Common - Transcriptional regulator VV2_0325 99 COG1846 MarR, Transcriptional regulators Transcription 27367207 Common - Fe-S oxidoreductase VV2_0798 159 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 27366628 Common - hypothetical protein VV2_0172 102 COG3177 COG3177, Uncharacterized conserved protein Function unknown 27367473 Common - Predicted hydrolase of the HAD superfamily VV2_1083 116 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 27367783 Common - hypothetical protein VV2_1420 27 None None None 27367159 Common - Preprotein translocase subunit SecD VV2_0745 174 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 27366750 Pathogen - Quinolinate synthase VV2_0306 1 None None None 27366563 Common - NTP pyrophosphohydrolase including oxidative damage repair enzyme VV2_0106 11 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 27367532 Common - Acetyl-CoA carboxylase beta subunit VV2_1148 167 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 27366574 Pathogen - hypothetical protein VV2_0118 1 None None None 27367319 Common - hypothetical protein VV2_0919 21 COG3602 COG3602, Uncharacterized protein conserved in bacteria Function unknown 27367235 Common - hypothetical protein VV2_0828 6 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 27366535 Common - Serine phosphatase RsbU, regulator of sigma subunit VV2_0076 22 None None None 27366829 Common - NAD(P)H-nitrite reductase VV2_0390 196 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 27367381 Common - Response regulator VV2_0986 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 27367640 Common - hypothetical protein VV2_1263 2 None None None 27366577 Common - Predicted membrane protein VV2_0121 51 COG1289 COG1289, Predicted membrane protein Function unknown 27367756 Common - Zn-dependent hydrolase VV2_1392 26 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 27366681 Common - hypothetical protein VV2_0229 2 None None None 27367226 Common artM arginine transporter permease subunit ArtM VV2_0818 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 27367632 Common - Putative threonine efflux protein VV2_1255 66 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 27367388 Common - Transcriptional regulator VV2_0993 132 COG0583 LysR, Transcriptional regulator Transcription 27366866 Common - Hemolysin-coregulated protein VV2_0429 23 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 27367258 Common - Putative silver efflux pump VV2_0852 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 27367627 Common - Glucan phosphorylase VV2_1250 143 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 27367185 Common - inner membrane protein YjeH VV2_0774 145 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 27367677 Pathogen - hypothetical protein VV2_1303 1 None None None 27367900 Common - Methyl-accepting chemotaxis protein VV2_1554 24 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 27367221 Common - Phenylalanyl-tRNA synthetase beta subunit VV2_0813 9 None None None 27366991 Common - Uncharacterized protein required for cytochrome oxidase assembly VV2_0561 67 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 27366877 Common - hypothetical protein VV2_0440 18 COG3913 SciT, Uncharacterized protein conserved in bacteria Function unknown 27367911 Common - hypothetical protein VV2_1565 100 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 27366671 Common - Formyltetrahydrofolate synthetase VV2_0217 88 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 27366875 Common - hypothetical protein VV2_0438 28 COG3515 COG3515, Uncharacterized protein conserved in bacteria Function unknown 27367542 Common - Methyl-accepting chemotaxis protein VV2_1160 26 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367295 Common - Arsenite efflux pump ACR3 VV2_0893 131 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 27366709 Common - Isopenicillin N synthase VV2_0260 54 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 27366600 Pathogen - hypothetical protein VV2_0144 1 None None None 27367516 Common - Transcriptional regulator VV2_1132 143 COG0583 LysR, Transcriptional regulator Transcription 27367868 Common - Small-conductance mechanosensitive channel VV2_1521 167 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 27366613 Common - Uncharacterized protein containing a von Willebrand factor type A (vWA) domain VV2_0157 75 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 27367861 Common - Autotransporter adhesin VV2_1514 111 None None None 27367172 Common - hypothetical protein VV2_0759 22 COG2926 COG2926, Uncharacterized protein conserved in bacteria Function unknown 27367585 Common - hypothetical protein VV2_1205 23 COG3085 COG3085, Uncharacterized protein conserved in bacteria Function unknown 27366811 Common - NAD(P)H-nitrite reductase VV2_0370 194 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 27367105 Common - Predicted esterase of the alpha/beta hydrolase fold VV2_0684 54 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 27367039 Common - hypothetical protein VV2_0611 3 None None None 27366560 Common - Signal transduction histidine kinase regulating citrate/malate metabolism VV2_0103 61 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 27367278 Common - Glutathione S-transferase VV2_0873 66 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 27366836 Common - Uroporphyrinogen-III methylase VV2_0397 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 27367705 Common - Ferredoxin VV2_1335 130 COG1146 COG1146, Ferredoxin Energy production and conversion 27367448 Pathogen - hypothetical protein VV2_1057 1 None None None 27366585 Common - Chromosome segregation ATPase VV2_0129 5 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 27367461 Common - Sugar kinase, ribokinase family VV2_1071 104 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 27367351 Common - AraC-type DNA-binding domain-containing protein VV2_0956 67 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27367929 Common - maltose/maltodextrin transporter ATP-binding protein VV2_1584 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 27367246 Common - Peptide arylation enzyme VV2_0840 222 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 27366763 Common - FOG: GGDEF domain VV2_0320 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367087 Common - hypothetical protein VV2_0662 4 None None None 27367214 Common - Predicted acetyltransferase/hydrolase VV2_0805 27 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 27367830 Common - Transcriptional regulator VV2_1478 182 COG0583 LysR, Transcriptional regulator Transcription 27367748 Common - Transcriptional regulator VV2_1382 173 COG0583 LysR, Transcriptional regulator Transcription 27366798 Common - Methyl-accepting chemotaxis protein VV2_0356 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366893 Common - acetyl-CoA synthetase VV2_0456 204 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 27366965 Common - peptidase T VV2_0532 60 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 27367939 Common - Sensor histidine kinase VV2_1595 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 27366570 Common - Predicted transcriptional regulator VV2_0113 98 COG0789 SoxR, Predicted transcriptional regulators Transcription 27366825 Common - Predicted SAM-dependent methyltransferase VV2_0386 9 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 27367617 Common - Pyridoxal/pyridoxine/pyridoxamine kinase VV2_1237 87 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 27367165 Common - hypothetical protein VV2_0751 4 None None None 27367348 Common - Transcriptional regulator VV2_0953 57 COG0583 LysR, Transcriptional regulator Transcription 27366948 Common - Phosphomannose isomerase VV2_0515 41 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 27367969 Common - hypothetical protein VV2_1628 20 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 27366757 Common - Signal transduction histidine kinase VV2_0314 149 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27366976 Common - Molybdopterin biosynthesis enzyme VV2_0544 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 27366734 Common - hypothetical protein VV2_0287 2 None None None 27367796 Common - hypothetical protein VV2_1434 21 COG1901 COG1901, Uncharacterized conserved protein Function unknown 27366485 Common - hypothetical protein VV2_0023 5 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 27366868 Common - hypothetical protein VV2_0431 44 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 27367871 Common - Methyl-accepting chemotaxis protein VV2_1524 133 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 161501865 Common - hypothetical protein VV2_0311 10 None None None 27366638 Pathogen - hypothetical protein VV2_0182 1 None None None 27366960 Common - Predicted phosphatase/phosphohexomutase VV2_0527 128 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 27366540 Common - hypothetical protein VV2_0082 43 COG4412 COG4412, Uncharacterized protein conserved in bacteria Function unknown 27366993 Common - hypothetical protein VV2_0563 21 COG3346 COG3346, Uncharacterized conserved protein Function unknown 27367555 Common - Translation elongation factors VV2_1175 2 None None None 27367741 Common - Predicted membrane protein VV2_1374 53 COG3326 COG3326, Predicted membrane protein Function unknown 27367046 Common - Transposase VV2_0618 13 None None None 27367508 Common - Response regulator VV2_1124 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 27367989 Common - GGDEF family protein VV2_1648 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367715 Common - hypothetical protein VV2_1345 19 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 27367021 Common - Na+/proline symporter VV2_0592 166 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 27367620 Common - hypothetical protein VV2_1240 85 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 27367437 Common - AraC-type DNA-binding domain-containing protein VV2_1046 142 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27366801 Common - Periplasmic protein TonB VV2_0360 38 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 27367757 Common - nitroreductase A VV2_1393 70 COG0778 NfnB, Nitroreductase Energy production and conversion 27367980 Common - Acetyltransferase VV2_1639 125 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 27366884 Common - Glutathione S-transferase VV2_0447 92 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 27367791 Common - Predicted hydrolase of the HAD superfamily VV2_1429 115 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 27367396 Common - ABC-type antimicrobial peptide transport system, ATPase component VV2_1004 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 27367485 Common - Sulfate permease VV2_1096 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 27367186 Common - Predicted glutamine amidotransferase VV2_0775 44 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 27367321 Common - Small-conductance mechanosensitive channel VV2_0921 21 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 27367493 Common - hypothetical protein VV2_1105 18 COG4289 COG4289, Uncharacterized protein conserved in bacteria Function unknown 27367847 Common - ATPase involved in DNA repair VV2_1497 12 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 27366927 Common - NAD-dependent aldehyde dehydrogenase VV2_0493 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 27367035 Common - hypothetical protein VV2_0607 7 None None None 27367816 Common - hypothetical protein VV2_1463 5 None None None 27366521 Common - D-ribose transporter ATP binding protein VV2_0062 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 27368005 Common - Serine-pyruvate aminotransferase VV2_1664 194 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 27367895 Common - Outer membrane receptor protein VV2_1549 130 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 27367195 Common - Multidrug resistance efflux pump VV2_0784 135 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27366496 Pathogen - Protein chain release factor A VV2_0034 1 None None None 27366636 Common - S-adenosylhomocysteine hydrolase VV2_0180 14 None None None 27367944 Common - hypothetical protein VV2_1601 2 None None None 27366694 Common - Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism VV2_0245 85 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 27367344 Common - Cytochrome c peroxidase VV2_0949 96 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 27367132 Common - Predicted sugar kinase VV2_0714 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 27366725 Common - Transcriptional regulator VV2_0277 142 COG0583 LysR, Transcriptional regulator Transcription 27366599 Common - ABC-type phosphate transport system, periplasmic component VV2_0143 150 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 27366467 Common - FOG: Transposase VV2_0004 28 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 27367237 Common - Non-ribosomal peptide synthetase modules VV2_0830 63 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 27366914 Common - ACP:hemolysin acyltransferase VV2_0480 13 COG2994 HlyC, ACP:hemolysin acyltransferase (hemolysin-activating protein) Posttranslational modification, protein turnover, chaperones 27366858 Common - Transposase VV2_0421 19 None None None 27367723 Common - Phosphotransferase system, fructose-specific IIC component VV2_1353 132 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 27367959 Common - Putative heme iron utilization protein VV2_1617 24 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 27366780 Common - anaerobic ribonucleoside triphosphate reductase VV2_0337 101 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 27367453 Common - Superfamily II DNA and RNA helicase VV2_1063 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 27367095 Common - Membrane protease subunit VV2_0671 160 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 27366626 Common - Multidrug resistance efflux pump VV2_0170 149 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27367832 Common - Transposase VV2_1480 28 None None None 27367146 Common - TRAP-type C4-dicarboxylate transport system, large permease component VV2_0731 125 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 27367902 Common - ABC-type phosphate transport system, periplasmic component VV2_1556 188 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 27366658 Common - ABC-type amino acid transport/signal transduction systems, periplasmic component/domain VV2_0203 10 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 27367597 Common - hypothetical protein VV2_1217 54 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 27367574 Pathogen - hypothetical protein VV2_1194 1 None None None 27367963 Common - Universal stress protein UspA VV2_1621 25 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 27367467 Common - NADH:flavin oxidoreductase VV2_1077 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 27366962 Common - Cation/multidrug efflux pump VV2_0529 180 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 27367976 Common - Spermidine synthase VV2_1635 83 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 27367076 Common - hypothetical protein VV2_0650 11 None None None 27367269 Common def peptide deformylase VV2_0863 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 27367470 Common ulaA ascorbate-specific PTS system enzyme IIC/IIB VV2_1080 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 27367262 Common - ATPase component of ABC transporter with duplicated ATPase domains VV2_0856 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 27367827 Pathogen - hypothetical protein VV2_1475 1 None None None 27366479 Common - Glucose/sorbosone dehydrogenase VV2_0016 114 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 27367074 Common - hypothetical protein VV2_0648 24 None None None 27367481 Common - Highly conserved protein containing a thioredoxin domain VV2_1092 19 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 27367209 Common - hypothetical protein VV2_0800 77 COG1556 COG1556, Uncharacterized conserved protein Function unknown 27366651 Common - Cation/multidrug efflux pump VV2_0195 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 161501856 Common rumB 23S rRNA metyluridine methyltransferase VV2_1394 183 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 27367850 Common - Zn-dependent hydrolase VV2_1502 36 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 27366546 Common - ATPase involved in chromosome partitioning VV2_0088 11 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 27367770 Common - Endonuclease I VV2_1406 28 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 27367859 Common - Probable sensor kinase VieS VV2_1512 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27367374 Common - Methyl-accepting chemotaxis protein VV2_0979 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366644 Common - serine hydroxymethyltransferase VV2_0188 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 27367999 Common - Methyl-accepting chemotaxis protein VV2_1658 119 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366602 Common - exoribonuclease II VV2_0146 192 COG4776 Rnb, Exoribonuclease II Transcription 27367565 Common - Permease of the major facilitator superfamily VV2_1185 1 None None None 27367636 Common - hypothetical protein VV2_1259 2 None None None 27366700 Common - Zn-dependent protease with chaperone function VV2_0251 129 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 27367737 Common - Cell division protein FtsI VV2_1370 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 27367336 Common - ABC-type branched-chain amino acid transport system, periplasmic component VV2_0939 143 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 27366649 Common - Membrane-fusion protein VV2_0193 157 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 27366557 Pathogen - hypothetical protein VV2_0100 1 None None None 27367150 Common - N-acetylmannosamine kinase VV2_0735 155 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 27366747 Pathogen - hypothetical protein VV2_0303 1 None None None 27368024 Common - TPR repeat containing protein VV2_1685 17 COG2912 COG2912, Uncharacterized conserved protein Function unknown 27367055 Common - IMP dehydrogenase/GMP reductase VV2_0629 24 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 27367779 Common - Putative NADH-flavin reductase VV2_1416 64 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 27367012 Common - Glutaredoxin VV2_0583 51 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 27367416 Common - Transcriptional regulator of sugar metabolism VV2_1025 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 27367652 Common - ABC-type amino acid transport/signal transduction system VV2_1276 2 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 27367044 Common - nucleoside diphosphate kinase regulator VV2_0616 73 COG0782 GreA, Transcription elongation factor Transcription 27366905 Common - Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component, eukaryotic type, alpha subunit VV2_0469 153 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 27367366 Pathogen - hypothetical protein VV2_0971 1 None None None 27366493 Common - Predicted membrane protein VV2_0031 59 COG3174 COG3174, Predicted membrane protein Function unknown 27366472 Pathogen - hypothetical protein VV2_0009 2 None None None 27367313 Common - Permease of the major facilitator superfamily VV2_0913 15 None None None 27367163 Common - Transcriptional regulator VV2_0749 168 COG1522 Lrp, Transcriptional regulators Transcription 27366664 Common - Signal transduction histidine kinase VV2_0209 219 COG4192 COG4192, Signal transduction histidine kinase regulating phosphoglycerate transport system Signal transduction mechanisms 27367764 Common - Oligoendopeptidase F VV2_1400 17 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 27367281 Common - DNA-binding HTH domain-containing protein VV2_0877 46 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 27367518 Common groEL chaperonin GroEL VV2_1134 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 27367293 Common - hypothetical protein VV2_0891 17 COG5591 COG5591, Uncharacterized conserved protein Function unknown 27367273 Common - Acetyltransferase VV2_0868 47 COG0456 RimI, Acetyltransferases General function prediction only 27367066 Common - hypothetical protein VV2_0640 25 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 27366879 Common - Flagellar motor protein VV2_0442 110 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 27367546 Common - Methyl-accepting chemotaxis protein VV2_1165 155 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367718 Common - Phosphomannose isomerase VV2_1348 42 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 27367253 Common - hypothetical protein VV2_0847 39 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 27367540 Common - Serine phosphatase RsbU, regulator of sigma subunit VV2_1158 214 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 27367979 Common - Signal transduction histidine kinase VV2_1638 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 27367625 Pathogen - hypothetical protein VV2_1245 1 None None None 27367286 Common - Multidrug resistance efflux pump VV2_0883 110 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27366864 Common - hypothetical protein VV2_0427 29 COG4104 COG4104, Uncharacterized conserved protein Function unknown 27367707 Common - Outer membrane receptor protein VV2_1337 121 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 27367082 Common - hypothetical protein VV2_0657 13 None None None 27367505 Common - DNA-binding HTH domain-containing protein VV2_1121 17 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 27366686 Common - Chloride channel protein EriC VV2_0235 16 None None None 27367866 Common - ABC-type phosphate transport system, periplasmic component VV2_1519 25 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 27366688 Common - 5'-nucleotidase/2',3'-cyclic phosphodiesterase VV2_0237 135 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 27367700 Common - Maltoporin VV2_1329 27 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 27366723 Common - FOG: GGDEF domain VV2_0275 183 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367153 Common - Poly(3-hydroxyalkanoate) synthetase VV2_0739 74 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 27367475 Common - putative L-xylulose 5-phosphate 3-epimerase VV2_1085 25 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 27367537 Common - Serine/threonine protein kinase VV2_1154 136 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 27367572 Common - Predicted signal transduction protein VV2_1192 101 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 27366775 Common - hypothetical protein VV2_0332 2 None None None 27366916 Common - ABC-type bacteriocin/lantibiotic exporter VV2_0482 243 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 27366870 Common - hypothetical protein VV2_0433 23 COG3518 COG3518, Uncharacterized protein conserved in bacteria Function unknown 27367873 Common - hypothetical protein VV2_1526 2 None None None 27367160 Pathogen - hypothetical protein VV2_0746 1 None None None 27366533 Common - Anti-anti-sigma regulatory factor VV2_0074 31 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 27367668 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease component VV2_1293 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 27366565 Pathogen - hypothetical protein VV2_0108 1 None None None 27367642 Common - NAD-dependent aldehyde dehydrogenase VV2_1266 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 27367972 Pathogen - hypothetical protein VV2_1631 1 None None None 27366752 Common - Predicted transcriptional regulator VV2_0308 3 None None None 27366989 Common - Outer membrane protein VV2_0559 169 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 27367916 Common - DNA-binding HTH domain-containing protein VV2_1570 137 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 27367510 Common - Predicted periplasmic protein VV2_1126 32 COG3672 COG3672, Predicted periplasmic protein Function unknown 27366634 Common - Predicted nucleotidyltransferase VV2_0178 8 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 27367794 Common - Membrane-associated phospholipid phosphatase VV2_1432 26 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 27366749 Pathogen - hypothetical protein VV2_0305 1 None None None 27367602 Common - FOG: GGDEF domain VV2_1222 174 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27366845 Common glpQ glycerophosphodiester phosphodiesterase VV2_0407 115 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 27367251 Pathogen - hypothetical protein VV2_0845 1 None None None 27366895 Common - Transcriptional regulator VV2_0458 172 COG0583 LysR, Transcriptional regulator Transcription 27367688 Common - hypothetical protein VV2_1316 6 None None None 27367946 Common - hypothetical protein VV2_1603 17 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 27367196 Common - Mg/Co/Ni transporter MgtE VV2_0785 154 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 27367530 Common - hypothetical protein VV2_1146 16 None None None 27367413 Common - N-acetylgalactosamine-specific PTS system transporter subunit IIB VV2_1022 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 27367670 Common - ABC-type oligopeptide transport system, ATPase component VV2_1295 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 27367228 Common - Uncharacterized protein contain chitin-binding domain type 3 VV2_0820 9 None None None 27367580 Common nagB glucosamine-6-phosphate deaminase VV2_1200 83 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 27367587 Pathogen - hypothetical protein VV2_1207 1 None None None 27366678 Common - hypothetical protein VV2_0226 32 COG3124 COG3124, Uncharacterized protein conserved in bacteria Function unknown 27367754 Pathogen - hypothetical protein VV2_1389 1 None None None 27366572 Pathogen - hypothetical protein VV2_0116 1 None None None 27366818 Common - Chemotaxis response regulator contains a CheY-like receiver domain and a methylesterase domain VV2_0378 150 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 27366500 Common - Predicted permease VV2_0040 25 None None None 27366736 Common - Ribonuclease G and E VV2_0290 14 None None None 27366967 Common - Predicted oxidoreductase VV2_0534 177 COG4989 COG4989, Predicted oxidoreductase General function prediction only 27368011 Common - Repressor protein PhnR, putative VV2_1671 122 COG2188 PhnF, Transcriptional regulators Transcription 27366523 Common - D-ribose transporter subunit RbsB VV2_0064 132 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 27366544 Common - Flp pilus assembly protein VV2_0086 139 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 27366759 Common - NAD/NADP transhydrogenase beta subunit VV2_0316 122 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 27366692 Common - Arginase/agmatinase/formimionoglutamate hydrolase VV2_0243 131 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 27366882 Common - hypothetical protein VV2_0445 26 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 27366662 Common - Sugar phosphate permease VV2_0207 81 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 27367060 Common - hypothetical protein VV2_0634 6 None None None 27367305 Common - Sugar kinase, ribokinase family VV2_0905 153 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 27367781 Common - Short-chain alcohol dehydrogenase of unknown specificity VV2_1418 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 27367213 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase VV2_0804 143 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 161501867 Common - ATP-dependent RNA helicase DbpA VV2_0136 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 27367667 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease component VV2_1292 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 27367353 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_0958 80 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 27366823 Common - hypothetical protein VV2_0383 9 None None None 27366508 Common - Membrane-associated phospholipid phosphatase VV2_0048 26 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 27367123 Common - Multidrug resistance efflux pump VV2_0704 122 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27367524 Common - Transcriptional regulator VV2_1140 125 COG1737 RpiR, Transcriptional regulators Transcription 27367820 Common - Chemotactic transducer-related protein VV2_1467 117 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 27367361 Common - dihydropteridine reductase VV2_0966 75 COG0778 NfnB, Nitroreductase Energy production and conversion 27367634 Common - pyrrolidone-carboxylate peptidase VV2_1257 58 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 27366719 Common - Allophanate hydrolase subunit 2 VV2_0271 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 27367200 Common - Predicted ATP-dependent protease VV2_0791 57 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 161501855 Common - hypothetical protein VV2_1409 43 COG3304 COG3304, Predicted membrane protein Function unknown 27367983 Common - hypothetical protein VV2_1642 3 None None None 27367920 Pathogen - hypothetical protein VV2_1574 1 None None None 27367422 Common - Transcriptional regulator VV2_1031 99 COG0583 LysR, Transcriptional regulator Transcription 27367242 Common - Peptide arylation enzyme VV2_0836 221 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 27367720 Common - AraC-type DNA-binding domain-containing protein VV2_1350 123 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27367358 Common - Predicted thioesterase VV2_0963 74 COG0824 FcbC, Predicted thioesterase General function prediction only 27367244 Common - Aryl carrier domain VV2_0838 74 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 27367404 Common - ABC-type Fe3+-hydroxamate transport system, periplasmic component VV2_1012 86 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 27367145 Common - Dihydrodipicolinate synthase/N-acetylneuraminate lyase VV2_0730 218 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 27367934 Common - Acyl-CoA hydrolase VV2_1589 130 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 27366827 Common - hypothetical protein VV2_0388 11 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 27367808 Common - ABC-type amino acid transport/signal transduction system VV2_1454 2 None None None 27367174 Common - FOG: CheY-like receiver VV2_0761 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27366830 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component VV2_0391 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 27367085 Common - hypothetical protein VV2_0660 6 None None None 27367991 Common - Predicted redox protein, regulator of disulfide bond formation VV2_1650 84 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 27367119 Common - Beta-lactamase class A VV2_0700 72 COG2367 PenP, Beta-lactamase class A Defense mechanisms 27367363 Common - Superfamily II DNA and RNA helicase VV2_0968 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 27367142 Common - hypothetical protein VV2_0726 13 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 27367650 Common - Ca2+/H+ antiporter VV2_1274 50 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 27367825 Common - AnkB protein VV2_1472 58 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 27366707 Common - hypothetical protein VV2_0258 113 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 27367330 Common - NTP pyrophosphohydrolase VV2_0932 2 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 27367230 Common - hypothetical protein VV2_0822 14 None None None 27367193 Common - AraC-type DNA-binding domain-containing protein VV2_0782 11 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27368026 Common - betaine aldehyde dehydrogenase VV2_1687 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 27367497 Common - Arylsulfatase A VV2_1109 82 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 27366478 Common - hypothetical protein VV2_0015 80 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 27367340 Common - hypothetical protein VV2_0944 21 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 27367352 Common - Permease of the major facilitator superfamily VV2_0957 220 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 27367034 Common - Lactoylglutathione lyase VV2_0606 25 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 27367094 Common - Membrane protease subunit VV2_0670 163 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 27367906 Common - GGDEF family protein VV2_1560 176 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367833 Pathogen - ATPase of the AAA+ class VV2_1481 1 None None None 27367368 Common - hypothetical protein VV2_0973 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 27367771 Pathogen - hypothetical protein VV2_1407 1 None None None 27367965 Common - Methyl-accepting chemotaxis protein VV2_1623 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367114 Common - Predicted permease VV2_0694 62 COG0628 PerM, Predicted permease General function prediction only 27366642 Common - glycine dehydrogenase VV2_0186 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 27367049 Pathogen - hypothetical protein VV2_0622 1 None None None 27367042 Common - Chromosome segregation ATPase VV2_0614 2 None None None 27367591 Common - hypothetical protein VV2_1211 49 COG1284 COG1284, Uncharacterized conserved protein Function unknown 27367387 Common - Signal transduction histidine kinase VV2_0992 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27367314 Common - 2-deoxy-D-gluconate 3-dehydrogenase VV2_0914 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 27367339 Common - elongation factor G VV2_0942 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 27366985 Common - hypothetical protein VV2_0555 20 None None None 27367182 Common - Putative threonine efflux protein VV2_0771 83 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 27366737 Pathogen - Chaperonin GroEL VV2_0291 1 None None None 27367734 Common - Transcriptional regulator VV2_1365 187 COG0583 LysR, Transcriptional regulator Transcription 27367122 Common - Permease of the major facilitator superfamily VV2_0703 3 COG1289 COG1289, Predicted membrane protein Function unknown 27367372 Common - Uncharacterized low-complexity protein VV2_0977 82 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 27367978 Common - 3-hydroxyisobutyrate dehydrogenase VV2_1637 192 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 27367285 Common - Transcriptional regulator VV2_0882 57 COG0583 LysR, Transcriptional regulator Transcription 27366740 Pathogen - Mg-dependent DNase VV2_0294 1 None None None 27367077 Common - Permease of the major facilitator superfamily VV2_0651 27 None None None 27367560 Common - GTP cyclohydrolase II VV2_1180 195 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 27367856 Common - GGDEF family protein VV2_1509 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27366804 Common - Biopolymer transport protein VV2_0363 38 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 27366466 Common - Predicted membrane protein VV2_0003 21 COG3059 COG3059, Predicted membrane protein Function unknown 27366790 Common - hypothetical protein VV2_0348 34 COG4102 COG4102, Uncharacterized protein conserved in bacteria Function unknown 27367488 Common - Methyl-accepting chemotaxis protein VV2_1099 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367712 Common - anaerobic nitric oxide reductase transcription regulator VV2_1342 171 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 27366764 Common - hypothetical protein VV2_0321 3 None None None 27367567 Common - hypothetical protein VV2_1187 4 None None None 27366593 Common - Signal transduction histidine kinase VV2_0137 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27366727 Common - hypothetical protein VV2_0279 5 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 27368007 Pathogen - hypothetical protein VV2_1666 1 None None None 27366851 Common - Zn-dependent protease with chaperone function VV2_0413 182 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 27368000 Common - Lipoate-protein ligase A VV2_1659 17 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 27366911 Common - Methyl-accepting chemotaxis protein VV2_0477 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366623 Common - NADH:ubiquinone oxidoreductase subunit 2 VV2_0167 2 None None None 27367028 Common - ABC-type multidrug transport system, permease component VV2_0599 183 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 27367611 Common - Glycosidase VV2_1231 78 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 27367154 Common - hypothetical protein VV2_0740 9 None None None 27367881 Common - Predicted membrane protein VV2_1534 12 COG4720 COG4720, Predicted membrane protein Function unknown 27366598 Common - Bacterial surface protein containing Ig-like domain VV2_0142 23 None None None 27367875 Common - Histone acetyltransferase HPA2 VV2_1528 70 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 27366937 Common - Cold shock protein VV2_0503 183 COG1278 CspC, Cold shock proteins Transcription 27367000 Common - Putative threonine efflux protein VV2_0571 61 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 27367415 Common - Predicted tagatose 6-phosphate kinase VV2_1024 34 COG4573 GatZ, Predicted tagatose 6-phosphate kinase Carbohydrate transport and metabolism 27367451 Common - Na+/H+ antiporter VV2_1061 48 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 27366856 Pathogen - Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein VV2_0419 5 None None None 27366957 Pathogen - hypothetical protein VV2_0524 1 None None None 27366739 Common - Methyl-accepting chemotaxis protein VV2_0293 2 None None None 27366881 Common - hypothetical protein VV2_0444 28 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 27366817 Common - Methylase of chemotaxis methyl-accepting protein VV2_0377 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 27367790 Common - Amidase related to nicotinamidase VV2_1428 73 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 27367949 Common - hypothetical protein VV2_1606 3 COG3691 COG3691, Uncharacterized protein conserved in bacteria Function unknown 27366615 Common - hypothetical protein VV2_0159 25 None None None 27367465 Common - Dehydrogenase VV2_1075 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 27367391 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase VV2_0996 145 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 27367575 Common - Methyl-accepting chemotaxis protein VV2_1195 114 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366486 Common - hypothetical protein VV2_0024 2 None None None 27367495 Common - Arylsulfatase regulator VV2_1107 109 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 27366711 Common - Acetyltransferase VV2_0262 64 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 27367797 Common - hypothetical protein VV2_1435 8 None None None 27366554 Common - Outer membrane protein VV2_0096 86 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 27366794 Common - AraC-type DNA-binding domain-containing protein VV2_0352 105 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27367956 Common - Periplasmic protein TonB VV2_1614 57 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 27366936 Common - Alkyl hydroperoxide reductase, large subunit VV2_0502 246 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 27367719 Common - Phosphotransferase system fructose-specific component IIB VV2_1349 139 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 27367188 Common - Predicted flavin-nucleotide-binding protein VV2_0777 31 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 27368014 Common - Transcriptional regulator VV2_1674 162 COG0583 LysR, Transcriptional regulator Transcription 27367676 Common - AraC-type DNA-binding domain-containing protein VV2_1302 120 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 27366758 Common - NAD/NADP transhydrogenase beta subunit VV2_0315 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 27367988 Common - malate synthase VV2_1647 48 COG2225 AceB, Malate synthase Energy production and conversion 27366929 Common - Predicted transcriptional regulator VV2_0495 59 COG0789 SoxR, Predicted transcriptional regulators Transcription 27366906 Common - Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase component, eukaryotic type, beta subunit VV2_0470 203 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 27367726 Common - Phosphotransferase system fructose-specific component IIB VV2_1356 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 27366518 Common - Predicted membrane protein VV2_0058 26 COG4539 COG4539, Predicted membrane protein Function unknown 27367181 Common - Peroxiredoxin VV2_0770 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 27367503 Common - bifunctional proline dehydrogenase/pyrroline-5-carboxylate dehydrogenase VV2_1118 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 27367888 Common - hypothetical protein VV2_1541 71 COG3272 COG3272, Uncharacterized conserved protein Function unknown 27367487 Common - CBS-domain-containing membrane protein VV2_1098 15 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 27367138 Common - hypothetical protein VV2_0720 24 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 27366952 Common - Cold shock protein VV2_0519 182 COG1278 CspC, Cold shock proteins Transcription 27367249 Common - Outer membrane receptor protein VV2_0843 85 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 27367101 Common - Permease of the major facilitator superfamily VV2_0680 12 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 27366556 Common - hypothetical protein VV2_0099 9 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 27366822 Common - Superfamily II DNA and RNA helicase VV2_0382 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 27367176 Common - hypothetical protein VV2_0763 12 None None None 27367792 Common - hypothetical protein VV2_1430 2 None None None 27367609 Common - Glycogen debranching enzyme VV2_1229 62 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 27367270 Common - hypothetical protein VV2_0864 5 None None None 27367589 Common - Methylated DNA-protein cysteine methyltransferase VV2_1209 220 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 27367665 Common - hypothetical protein VV2_1290 14 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 27367444 Common - AraC-type DNA-binding domain-containing protein VV2_1053 88 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27367036 Common - Superfamily II DNA and RNA helicase VV2_0608 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 27366847 Common - Predicted Zn-dependent protease VV2_0409 155 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 27367818 Common - Transcriptional regulator VV2_1465 167 COG0583 LysR, Transcriptional regulator Transcription 27366587 Common - Nitrate/TMAO reductase VV2_0131 48 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 27368016 Common - Dipeptide/tripeptide permease VV2_1676 74 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 27367897 Common - hypothetical protein VV2_1551 8 None None None 27367600 Common - Pirin-related protein VV2_1220 147 COG1741 COG1741, Pirin-related protein General function prediction only 27367925 Common - ATPase involved in chromosome partitioning VV2_1579 147 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 27367806 Common - AraC-type DNA-binding domain-containing protein VV2_1452 99 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27367936 Common - AraC-type DNA-binding domain-containing protein VV2_1592 96 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27367202 Common - hypothetical protein VV2_0793 2 None None None 27367686 Common - Chromosome segregation ATPase VV2_1314 19 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 27367240 Common - 2,3-dihydroxybenzoate-2,3-dehydrogenase VV2_0834 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 27366676 Common - Predicted phosphatase/phosphohexomutase VV2_0222 92 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 27367291 Common - Predicted membrane-associated metal-dependent hydrolase VV2_0889 61 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 27366468 Common - phosphoenolpyruvate synthase VV2_0005 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 27367780 Common - Transcriptional regulator VV2_1417 150 COG0583 LysR, Transcriptional regulator Transcription 27367482 Common - 2-deoxy-D-gluconate 3-dehydrogenase VV2_1093 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 27367210 Common - Fe-S oxidoreductase VV2_0801 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 27366969 Pathogen - hypothetical protein VV2_0536 1 None None None 27367476 Common - hypothetical protein VV2_1086 2 None None None 27367767 Common - FOG: GGDEF domain VV2_1403 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 27367300 Common - hypothetical protein VV2_0899 15 COG0700 SpmB, Uncharacterized membrane protein Function unknown 27367709 Common - hypothetical protein VV2_1339 6 None None None 27367428 Common - Conserved domain frequently associated with peptide methionine sulfoxide reductase VV2_1037 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 27367582 Common - hypothetical protein VV2_1202 16 COG3930 COG3930, Uncharacterized protein conserved in bacteria Function unknown 27366698 Common - Long-chain fatty acid transport protein VV2_0249 77 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 27366730 Common - translation initiation factor Sui1 VV2_0282 51 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 27366888 Pathogen - hypothetical protein VV2_0451 1 None None None 27367406 Common - Transcriptional regulator VV2_1014 17 COG1802 GntR, Transcriptional regulators Transcription 27367354 Common - ATPase involved in DNA repair VV2_0959 8 None None None 27366691 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_0241 138 COG2962 RarD, Predicted permeases General function prediction only 27367062 Common - hypothetical protein VV2_0636 3 None None None 27366944 Common - Response regulator VV2_0511 184 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 27367084 Common - Type IV secretory pathway, VirD4 component VV2_0659 33 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 27366501 Common - Predicted permease VV2_0041 11 COG0730 COG0730, Predicted permeases General function prediction only 27366713 Common - Predicted signal transduction protein VV2_0264 165 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 27366831 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, permease component VV2_0392 148 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 161501868 Common - putative chaperone VV2_0020 228 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 27367275 Common - Transcriptional activator of acetoin/glycerol metabolism VV2_0870 178 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 27367702 Common - melibiose:sodium symporter VV2_1332 80 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 161501861 Common - Uncharacterized membrane protein required for alginate biosynthesis VV2_0950 14 COG3136 GlpM, Uncharacterized membrane protein required for alginate biosynthesis General function prediction only 27366964 Common - Deoxycytidylate deaminase VV2_0531 79 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 27367931 Common malF maltose transporter membrane protein VV2_1586 158 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 27366773 Common - cobyric acid synthase VV2_0330 156 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 27367628 Common malQ 4-alpha-glucanotransferase VV2_1251 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 27367535 Common - Transposase VV2_1151 79 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 27367974 Common - Membrane protein VV2_1633 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 27367424 Common - Predicted acetyltransferase VV2_1033 31 COG3153 COG3153, Predicted acetyltransferase General function prediction only 27367645 Common - Na+/phosphate symporter VV2_1269 90 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 27366913 Common - Autotransporter adhesin VV2_0479 137 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 27366632 Common - hypothetical protein VV2_0176 2 None None None 27367943 Common - nicotinic acid mononucleotide adenylyltransferase VV2_1600 18 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 27367659 Common - ABC-type sugar transport system, periplasmic component VV2_1283 84 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 27367547 Common - Chemotaxis signal transduction protein VV2_1166 128 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 27367696 Common - galactose/methyl galaxtoside transporter ATP-binding protein VV2_1325 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 27367168 Common - hypothetical protein VV2_0754 10 None None None 27367762 Pathogen - hypothetical protein VV2_1398 1 None None None 27367378 Common - hypothetical protein VV2_0983 96 COG0579 COG0579, Predicted dehydrogenase General function prediction only 27367438 Common - FOG: Transposase VV2_1047 28 COG3385 COG3385, FOG: Transposase and inactivated derivatives DNA replication, recombination, and repair 27367222 Common - Uncharacterized lipoprotein NlpE VV2_0814 24 COG3015 CutF, Uncharacterized lipoprotein NlpE involved in copper resistance Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism 27367403 Common - ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component VV2_1011 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 27366480 Common - Predicted membrane protein VV2_0018 34 COG3326 COG3326, Predicted membrane protein Function unknown 27367648 Common - Transcriptional regulator VV2_1272 164 COG0583 LysR, Transcriptional regulator Transcription 27366778 Common - Methyl-accepting chemotaxis protein VV2_0335 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366567 Common - ABC-type enterochelin transport system, permease component VV2_0110 125 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 27366489 Common - Membrane-fusion protein VV2_0027 173 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 27367912 Common - MoxR-like ATPase VV2_1566 186 COG0714 COG0714, MoxR-like ATPases General function prediction only 27367953 Common - ABC-type hemin transport system, periplasmic component VV2_1611 123 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 27366684 Common - FOG: CBS domain VV2_0232 114 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 27367322 Common - hypothetical protein VV2_0922 31 None None None 27366890 Common - Predicted signal transduction protein VV2_0453 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 27366995 Common - cytochrome C oxidase assembly protein VV2_0566 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 27366551 Common - hypothetical protein VV2_0093 3 None None None 27367673 Common - Exo-beta-1,3-glucanase VV2_1298 15 COG5309 COG5309, Exo-beta-1,3-glucanase Carbohydrate transport and metabolism 27366607 Common - Arylsulfatase A VV2_0151 82 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 27367848 Common - Bacterial lipocalin VV2_1500 67 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 27366871 Common - Protein of avirulence locus VV2_0434 21 COG4455 ImpE, Protein of avirulence locus involved in temperature-dependent protein secretion General function prediction only 27367512 Common - ABC-type bacteriocin/lantibiotic exporter VV2_1128 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 27367068 Pathogen - hypothetical protein VV2_0642 1 None None None 27366659 Common - hypothetical protein VV2_0204 21 COG2501 COG2501, Uncharacterized conserved protein Function unknown 27367255 Pathogen - hypothetical protein VV2_0849 1 None None None 27367960 Common - hypothetical protein VV2_1618 47 COG2096 COG2096, Uncharacterized conserved protein Function unknown 27366617 Common - Uncharacterized protein of the AP superfamily VV2_0161 18 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 27367914 Common - Chromosome segregation ATPase VV2_1568 1 None None None 27367299 Common - Acetylornithine deacetylase VV2_0898 77 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 27367864 Common - Agglutination protein VV2_1517 133 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 27366610 Common - MoxR-like ATPase VV2_0154 176 COG0714 COG0714, MoxR-like ATPases General function prediction only 27366980 Common - Predicted signal transduction protein VV2_0548 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 27367558 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component VV2_1178 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 27366674 Common - hypothetical protein VV2_0220 2 None None None 27366542 Common - Flp pilus assembly protein VV2_0084 3 COG4907 COG4907, Predicted membrane protein Function unknown 27367886 Common - Transposase VV2_1539 11 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 27366974 Common - Mn2+ and Fe2+ transporter of the NRAMP family VV2_0542 28 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 27366484 Common - Rhodanese-related sulfurtransferase VV2_0022 133 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 27367774 Common - Phosphoglycerol transferase VV2_1410 72 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 27367680 Common - hypothetical protein VV2_1307 2 None None None 27366934 Common - Isopropylmalate/homocitrate/citramalate synthase VV2_0500 113 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 27366987 Common - Methyl-accepting chemotaxis protein VV2_0557 162 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367577 Common - Na+/glutamate symporter VV2_1197 53 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 27366640 Pathogen - hypothetical protein VV2_0184 1 None None None 27367112 Common - NAD-dependent protein deacetylase, SIR2 family VV2_0692 30 None None None 27366654 Common - Fructose-1-phosphate kinase VV2_0199 139 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 27367606 Common - Type II secretory pathway protein VV2_1226 139 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 27367993 Common - Predicted transcriptional regulator VV2_1652 106 COG2378 COG2378, Predicted transcriptional regulator Transcription 27367001 Common - AraC-type DNA-binding domain-containing protein VV2_0572 71 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27366742 Pathogen - Membrane protein VV2_0297 1 None None None 27367099 Common - hypothetical protein VV2_0676 39 COG3367 COG3367, Uncharacterized conserved protein Function unknown 27367184 Common - Transcriptional regulator VV2_0773 151 COG1522 Lrp, Transcriptional regulators Transcription 27367005 Common - Transcriptional regulator VV2_0576 131 COG1846 MarR, Transcriptional regulators Transcription 27367316 Common - Predicted signal transduction protein VV2_0916 120 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 27367370 Common - Phosphoglycerate dehydrogenase VV2_0975 229 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 27367618 Common - Na+/serine symporter VV2_1238 151 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 27367901 Common - Methyl-accepting chemotaxis protein VV2_1555 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367562 Common - Signal transduction histidine kinase VV2_1182 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27367265 Common - Transcriptional regulator VV2_0859 127 COG1609 PurR, Transcriptional regulators Transcription 27367018 Common - Putative translation initiation inhibitor, yjgF family VV2_0589 90 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 27367283 Common - Predicted dehydrogenase VV2_0879 176 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 27367854 Pathogen - hypothetical protein VV2_1506 1 None None None 27367079 Common - Transposase VV2_0654 72 None None None 27366945 Common - sensory histidine kinase UhpB VV2_0512 145 COG3851 UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific Signal transduction mechanisms 27366908 Common - Electron transfer flavoprotein, alpha subunit VV2_0473 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 27367593 Common - Na+/H+ antiporter NhaD VV2_1213 51 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 27367070 Common - hypothetical protein VV2_0644 20 None None None 27367458 Common - TRAP-type C4-dicarboxylate transport system, large permease component VV2_1068 123 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 27366894 Common - SAM-dependent methyltransferase VV2_0457 57 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 27366539 Common - ATPase involved in DNA repair VV2_0080 142 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 27367232 Common - Methyl-accepting chemotaxis protein VV2_0825 142 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367867 Common - Carbonic anhydrase VV2_1520 52 COG3338 Cah, Carbonic anhydrase Inorganic ion transport and metabolism 27367746 Common - hypothetical protein VV2_1380 33 COG4340 COG4340, Uncharacterized protein conserved in bacteria Function unknown 27366668 Common - Chitinase VV2_0213 62 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 27366525 Common - Transcriptional regulator VV2_0066 128 COG1609 PurR, Transcriptional regulators Transcription 27366761 Common - hypothetical protein VV2_0318 15 COG5453 COG5453, Uncharacterized conserved protein Function unknown 27367032 Common - Co/Zn/Cd efflux system component VV2_0603 165 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 27366922 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase VV2_0488 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 27367843 Common - DNA-damage-inducible protein J VV2_1492 4 None None None 27366476 Common - Predicted phosphatase VV2_0013 35 COG0546 Gph, Predicted phosphatases General function prediction only 27367408 Common gatY tagatose-bisphosphate aldolase VV2_1017 179 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 27366839 Common - Glycosidase VV2_0400 48 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 27366953 Common - hypothetical protein VV2_0520 52 COG4681 COG4681, Uncharacterized protein conserved in bacteria Function unknown 27367332 Common - AraC-type DNA-binding domain-containing protein VV2_0934 58 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 27367835 Common - Phospholipase/lecithinase/hemolysin VV2_1483 36 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 27367908 Common - TPR repeat containing protein VV2_1562 54 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 27366703 Common - ABC-type uncharacterized transport system, periplasmic component VV2_0254 91 COG4533 COG4533, ABC-type uncharacterized transport system, periplasmic component General function prediction only 27367108 Common - ABC-type sulfate transport system, permease component VV2_0687 222 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 27367824 Common - Cu/Zn superoxide dismutase VV2_1471 86 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 27367570 Common - hypothetical protein VV2_1190 16 None None None 27366705 Common - Glycosidase VV2_0256 158 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 27367059 Common - hypothetical protein VV2_0633 15 None None None 27366552 Common - hypothetical protein VV2_0094 4 None None None 27367136 Common - Response regulator VV2_0718 201 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 27367393 Common - Outer membrane protein VV2_0999 7 None None None 27367054 Common - hypothetical protein VV2_0627 20 COG2378 COG2378, Predicted transcriptional regulator Transcription 27367787 Common - Glutamate decarboxylase VV2_1425 15 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 27366497 Common - hypothetical protein VV2_0035 14 None None None 27366931 Common - Acetyl-CoA carboxylase, carboxyltransferase component VV2_0497 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 27366621 Common - hypothetical protein VV2_0165 12 None None None 27367678 Common - Beta-glucosidase-related glycosidase VV2_1304 89 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 27367985 Common - GGDEF family protein VV2_1644 179 COG3452 COG3452, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 27366982 Common - Transcriptional regulator VV2_0550 68 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 27367954 Common - Biopolymer transport protein VV2_1612 6 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 27367986 Common - Methyl-accepting chemotaxis protein VV2_1645 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366796 Common - hypothetical protein VV2_0354 23 None None None 27367968 Pathogen - Lipid A core - O-antigen ligase VV2_1627 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 27367728 Common - Phosphoserine phosphatase VV2_1358 66 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 27367760 Common - DNA-binding HTH domain-containing protein VV2_1396 7 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 27367891 Common - hypothetical protein VV2_1544 82 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 27368002 Common - AraC-type DNA-binding domain-containing protein VV2_1661 137 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 27366854 Common - hypothetical protein VV2_0416 10 None None None 27367940 Common - dihydroorotase VV2_1596 89 COG0418 PyrC, Dihydroorotase Nucleotide transport and metabolism 27366784 Common - Predicted transporter component VV2_0342 69 COG2391 COG2391, Predicted transporter component General function prediction only 27366591 Common - hypothetical protein VV2_0135 6 None None None 27366581 Common - FOG: CheY-like receiver VV2_0125 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27366990 Common - protoheme IX farnesyltransferase VV2_0560 192 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 27366792 Common - thioredoxin 2 VV2_0350 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 27366595 Common - Response regulator VV2_0139 40 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 27367812 Common - Spermidine/putrescine-binding periplasmic protein VV2_1458 136 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 27366959 Common - FKBP-type peptidyl-prolyl cis-trans isomerase 1 VV2_0526 136 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 27367633 Common - Transcriptional regulator VV2_1256 153 COG1522 Lrp, Transcriptional regulators Transcription 27367026 Common - Membrane-fusion protein VV2_0597 129 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 27367157 Common - Preprotein translocase subunit SecF VV2_0743 201 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 27367994 Common - hypothetical protein VV2_1653 6 None None None 27367499 Common - hypothetical protein VV2_1111 10 COG4399 COG4399, Uncharacterized protein conserved in bacteria Function unknown 27367382 Common - Signal transduction histidine kinase VV2_0987 206 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 27367399 Common - Outer membrane protein VV2_1007 124 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 27366816 Common - Signal transduction histidine kinase VV2_0376 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27367966 Common - Methyl-accepting chemotaxis protein VV2_1624 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367877 Common - Periplasmic protease VV2_1530 44 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 27366918 Common - ABC-type bacteriocin/lantibiotic exporters VV2_0484 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 27366609 Pathogen - hypothetical protein VV2_0153 1 None None None 27367519 Common groES co-chaperonin GroES VV2_1135 214 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 27367171 Pathogen - hypothetical protein VV2_0757 1 None None None 27367302 Common - hypothetical protein VV2_0902 45 COG3439 COG3439, Uncharacterized conserved protein Function unknown 27367765 Common - Transcriptional regulator VV2_1401 196 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 27366744 Common - Predicted ATPase VV2_0300 4 COG0433 COG0433, Predicted ATPase General function prediction only 27366814 Common - hypothetical protein VV2_0374 2 None None None 27367899 Common - Methyl-accepting chemotaxis protein VV2_1553 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27366732 Pathogen - hypothetical protein VV2_0284 1 None None None 27367731 Common - Beta-galactosidase/beta-glucuronidase VV2_1361 40 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 27366696 Pathogen - hypothetical protein VV2_0247 1 None None None 27367356 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_0961 136 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 27367309 Common - Thymidylate kinase VV2_0909 2 None None None 27367631 Common - 2-methylthioadenine synthetase VV2_1254 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 27367426 Common - Uncharacterized ABC-type transport system, permease component VV2_1035 43 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 27367219 Common - FOG: EAL domain protein VV2_0811 171 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 27367024 Common - Predicted amino acid aldolase or racemase VV2_0595 57 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 27367128 Common - Predicted transcriptional regulator VV2_0710 11 None None None 27366971 Common - hypothetical protein VV2_0538 3 None None None 27366549 Common - Flp pilus assembly protein TadC VV2_0091 21 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 27366516 Common yieM hypothetical protein VV2_0056 28 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 27367584 Common - glutathione synthetase VV2_1204 134 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 27367418 Common - Permease of the drug/metabolite transporter (DMT) superfamily VV2_1027 45 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 161501863 Common uhpT sugar phosphate antiporter VV2_0510 52 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 27366527 Common - FOG: CheY-like receiver VV2_0068 219 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 27366861 Pathogen - Helicase subunit of the DNA excision repair complex VV2_0424 1 None None None 27367247 Common - Aryl carrier domain VV2_0841 21 COG3433 COG3433, Aryl carrier domain Secondary metabolites biosynthesis, transport, and catabolism 27367088 Common - ATP-dependent exoDNAse, alpha subunit VV2_0663 57 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 27366834 Common - Dienelactone hydrolase VV2_0395 108 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 27367904 Common - ABC-type phosphate transport system, permease component VV2_1558 233 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 27367785 Pathogen - hypothetical protein VV2_1423 1 None None None 27367528 Common - FOG: EAL domain protein VV2_1144 150 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 27368028 Common - ABC-type proline/glycine betaine transport system, periplasmic component VV2_1689 66 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 27366841 Common - Methyl-accepting chemotaxis protein VV2_0402 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 27367239 Common - phospho-2-dehydro-3-deoxyheptonate aldolase VV2_0833 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 27366766 Common - hypothetical protein VV2_0323 2 None None None 27367657 Common - Maltoporin VV2_1281 24 COG4580 LamB, Maltoporin (phage lambda and maltose receptor) Carbohydrate transport and metabolism 27366504 Common - N-acetylglucosamine-binding protein A VV2_0044 33 COG3397 COG3397, Uncharacterized protein conserved in bacteria Function unknown 27367446 Common - hypothetical protein VV2_1055 78 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 27367440 Common - Transcriptional regulator VV2_1049 184 COG0583 LysR, Transcriptional regulator Transcription 27367178 Pathogen - hypothetical protein VV2_0766 1 None None None 27367638 Common - Phosphoserine phosphatase VV2_1261 37 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 27367272 Common - Hemolysin VV2_0867 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 27367910 Common - hypothetical protein VV2_1564 2 None None None 27366579 Common mgsA methylglyoxal synthase VV2_0123 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 27367432 Common - ABC-type sugar transport system, periplasmic component VV2_1041 65 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 27367325 Pathogen - Methyl-accepting chemotaxis protein VV2_0926 1 None None None 27367841 Pathogen - hypothetical protein VV2_1489 1 None None None 27366652 Common - Outer membrane protein VV2_0196 4 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 27366682 Common - Cytochrome B561 VV2_0230 59 COG3038 CybB, Cytochrome B561 Energy production and conversion 27366537 Common - Response regulator VV2_0078 224 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 27367869 Common - Predicted transcriptional regulator protein VV2_1522 2 None None None 27367514 Common - C4-dicarboxylate transporter VV2_1130 23 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 27366873 Common - hypothetical protein VV2_0436 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 27367385 Common - hypothetical protein VV2_0990 2 COG1568 COG1568, Predicted methyltransferases General function prediction only 27366899 Common - ABC-type sugar transport system, ATPase component VV2_0463 20 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 27367683 Pathogen - hypothetical protein VV2_1310 3 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 27367257 Common - hypothetical protein VV2_0851 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 27367543 Common - Chemotaxis response regulator VV2_1161 214 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 27366771 Common modB molybdate ABC transporter permease protein VV2_0328 234 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 27366619 Common - Arylsulfatase regulator VV2_0163 88 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 27366672 Common - Ribokinase family sugar kinase VV2_0218 65 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 27366892 Common phhA phenylalanine 4-monooxygenase VV2_0455 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 27367297 Common - ABC-type amino acid transport/signal transduction system VV2_0896 6 None None None 27367951 Common - ABC-type hemin transport system, ATPase component VV2_1609 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 27367569 Common - ABC-type transport system, involved in lipoprotein release, permease component VV2_1189 108 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 27367310 Pathogen - hypothetical protein VV2_0910 1 None None None 27367647 Common - Lactoylglutathione lyase VV2_1271 18 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 27367166 Common - Signal transduction histidine kinase VV2_0752 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 27367743 Common - Transcriptional regulator VV2_1377 168 COG0583 LysR, Transcriptional regulator Transcription 27367736 Common - hypothetical protein VV2_1369 28 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 27367615 Common - Arginine/lysine/ornithine decarboxylase VV2_1235 81 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 27367533 Common - hypothetical protein VV2_1149 13 None None None 27367064 Common - Type IV secretory pathway, VirB4 component VV2_0638 29 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 27366716 Common - Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component VV2_0267 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 27366569 Common - ABC-type enterochelin transport system, ATPase component VV2_0112 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 27367551 Pathogen - Anti-anti-sigma regulatory factor VV2_1170 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 27366820 Common - Transcriptional regulator VV2_0380 94 COG1414 IclR, Transcriptional regulator Transcription 27367927 Common - hypothetical protein VV2_1581 13 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 27366776 Common - hypothetical protein VV2_0333 39 COG4067 COG4067, Uncharacterized protein conserved in archaea Posttranslational modification, protein turnover, chaperones 27367204 Common - Serine protease of the peptidase family S9A VV2_0795 121 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 27367224 Common - ABC-type amino acid transport/signal transduction system VV2_0816 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 27366849 Common dcuC C4-dicarboxylate transporter DcuC VV2_0411 35 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 27367478 Common - ABC-type multidrug transport system, ATPase and permease component VV2_1089 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 27367933 Pathogen - hypothetical protein VV2_1588 1 None None None 27367263 Pathogen - hypothetical protein VV2_0857 1 None None None 27367549 Common - Chemotaxis protein histidine kinase VV2_1168 157 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 27367401 Common - hypothetical protein VV2_1009 1 None None None