Brucella melitensis 16M chromosome I, complete sequence NC_003317 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 17986337 Common - CATION-TRANSPORTING ATPASE PACS BMEI0053 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 17988262 Common - O-SIALOGLYCOPROTEIN ENDOPEPTIDASE BMEI1979 190 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 17986620 Common - BIOPOLYMER TRANSPORT EXBD PROTEIN BMEI0337 138 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 17988031 Common - TRANSCRIPTIONAL REGULATOR BMEI1748 73 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 17988220 Common - OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN OPPC BMEI1937 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 17987058 Common rpmD 50S ribosomal protein L30 BMEI0775 84 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 17987927 Common - dihydropyrimidinase BMEI1644 208 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 17988021 Common - TRANSCRIPTIONAL ACTIVATOR TENA BMEI1738 74 COG0819 TenA, Putative transcription activator Transcription 17988155 Common - CELL SURFACE PROTEIN BMEI1872 31 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 17986466 Common - BIOTIN SYNTHESIS PROTEIN BIOC BMEI0182 80 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 17986831 Common - FLAVOHEMOPROTEIN BMEI0548 139 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 17986679 Common - DIHYDROXYACETONE KINASE BMEI0396 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 17986609 Common - MYO-INOSITOL-1(OR 4)-MONOPHOSPHATASE BMEI0326 215 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 17987902 Common hslO Hsp33-like chaperonin BMEI1619 130 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 17986741 Common - Hypothetical Membrane Spanning Protein BMEI0458 31 None None None 17986925 Common - UREA TRANSPORTER BMEI0642 18 COG4413 Utp, Urea transporter Amino acid transport and metabolism 17986900 Common - acetolactate synthase 3 catalytic subunit BMEI0617 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 17986456 Common - hypothetical protein BMEI0172 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 17987991 Common - 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE / 5-CARBOXYMETHYL-2-OXO-HEX-3-ENE-1,7-DIOATE DECARBOXYLASE BMEI1708 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 17988215 Pathogen - Hypothetical Cytosolic Protein BMEI1932 2 None None None 17987675 Common - RIBOSE TRANSPORT ATP-BINDING PROTEIN RBSA BMEI1392 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 17987254 Common - PHOSPHO-2-DEHYDRO-3-DEOXYHEPTONATE ALDOLASE BMEI0971 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 17986563 Common rpoH2 RNA polymerase factor sigma-32 BMEI0280 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 17986701 Common - LIPOOLIGOSACCHARIDE BIOSYNTHESIS PROTEIN LIC2B BMEI0418 30 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 17987997 Common - MALTOSE TRANSPORT SYSTEM PERMEASE PROTEIN MALG BMEI1714 183 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 17987238 Common - DIHYDRONEOPTERIN ALDOLASE BMEI0955 75 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 17986329 Common - BOLA PROTEIN BMEI0045 97 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 17986989 Common - COBC PROTEIN BMEI0706 152 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 17986922 Common - CBIM PROTEIN BMEI0639 3 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 17988274 Pathogen - hypothetical protein BMEI1991 1 None None None 17986617 Common ruvB Holliday junction DNA helicase B BMEI0334 229 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 17986862 Common murG N-acetylglucosaminyl transferase BMEI0579 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 17987048 Common - 50S ribosomal protein L29 BMEI0765 173 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 17986375 Common - hypothetical protein BMEI0091 4 None None None 17987852 Common - NITROGEN FIXATION PROTEIN FIXI (E1-E2 TYPE CATION ATPASE FIXI) BMEI1569 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 17986882 Common - D-LACTATE DEHYDROGENASE (CYTOCHROME) BMEI0599 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 17986602 Common - BIOY PROTEIN BMEI0319 105 COG1268 BioY, Uncharacterized conserved protein General function prediction only 17987787 Common - acetylspermidine deacetylase BMEI1504 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 17988177 Common - GRAMICIDIN S BIOSYNTHESIS GRST PROTEIN BMEI1894 49 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 17987350 Common - ACETYLTRANSFERASE BMEI1067 34 COG0456 RimI, Acetyltransferases General function prediction only 17987649 Pathogen - Hypothetical Membrane Spanning Protein BMEI1366 2 None None None 17987708 Pathogen - hypothetical protein BMEI1425 1 None None None 17986659 Common - hypothetical protein BMEI0376 7 None None None 17986723 Common - GLYCINE BETAINE/L-PROLINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW BMEI0440 214 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 17987003 Common - sugar fermentation stimulation protein A BMEI0720 106 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 17987065 Common rplQ 50S ribosomal protein L17 BMEI0782 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 17986380 Common - ELECTRON TRANSFER FLAVOPROTEIN BETA-SUBUNIT BMEI0096 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 17986672 Pathogen - hypothetical protein BMEI0389 1 None None None 17986956 Common - THIOSULFATE-BINDING PROTEIN PRECURSOR BMEI0673 88 COG4150 CysP, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 17986597 Pathogen - hypothetical protein BMEI0314 1 None None None 17988225 Common - DNA polymerase III subunit beta BMEI1942 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 17986366 Common - hypoxanthine-guanine phosphoribosyltransferase BMEI0082 137 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 17986525 Common - PHOSPHATE REGULON SENSOR PROTEIN PHOR BMEI0241 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 17987220 Common - PUTATIVE COMPETENCE-DAMAGE PROTEIN BMEI0937 166 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 17986635 Common - hypothetical transcription regulator BMEI0352 13 None None None 17986855 Common - hypothetical protein BMEI0572 17 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 17986825 Common - hypothetical protein BMEI0542 19 None None None 17987740 Common rnhA ribonuclease H BMEI1457 180 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 17986474 Common - PHOSPHOENOLPYRUVATE-PROTEIN PHOSPHOTRANSFERASE PTSP BMEI0190 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 17987227 Common - putative transport BMEI0944 69 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 17987345 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit BMEI1062 188 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 17986302 Common - Hypothetical Cytosolic Protein BMEI0018 21 None None None 17986387 Common - methionine gamma-lyase BMEI0103 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 17987549 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase BMEI1266 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 17986892 Common - DIHYDROFOLATE REDUCTASE BMEI0609 147 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 17987883 Common - UREASE OPERON 23 KDA ACCESSORY PROTEIN BMEI1600 5 None None None 17986313 Common - L-SORBOSE DEHYDROGENASE [FAD] BMEI0029 87 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 17987985 Common - TRANSPOSASE BMEI1702 91 COG0582 XerC, Integrase DNA replication, recombination, and repair 17988137 Pathogen - hypothetical protein BMEI1854 1 None None None 17987956 Common - zinc-binding protein BMEI1673 30 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 17987208 Common - ALCOHOL DEHYDROGENASE BMEI0925 201 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 17986627 Common - PHOSPHOGLUCOSAMINE MUTASE / PHOSPHOACETYLGLUCOSAMINE MUTASE / PHOSPHOMANNOMUTASE BMEI0344 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 17987506 Common - TRANSPOSASE BMEI1223 50 None None None 17987183 Pathogen - hypothetical protein BMEI0900 1 None None None 17986799 Common - aspartate aminotransferase BMEI0516 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 17987695 Common - TRANSPOSASE BMEI1412 50 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17986951 Common - CALCIUM BINDING PROTEIN BMEI0668 8 None None None 17987758 Common acpP acyl carrier protein BMEI1475 206 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 17986990 Common - CBIB PROTEIN BMEI0707 146 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 17986498 Common - TAIL-SPECIFIC PROTEASE BMEI0214 183 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 17987606 Common - TRANSPORTER, DME FAMILY BMEI1323 100 COG2962 RarD, Predicted permeases General function prediction only 17986769 Common - Hypothetical Cytosolic Protein BMEI0486 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 17986812 Common - SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN BMEI0529 54 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 17988081 Common - 23S ribosomal RNA methyltransferase BMEI1798 214 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 17987141 Pathogen - hypothetical protein BMEI0858 2 None None None 17987582 Common - Hypothetical Cytosolic Protein BMEI1299 62 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 17987858 Common - XANTHINE DEHYDROGENASE BMEI1575 113 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 17987666 Common - TRANSCRIPTIONAL REGULATOR, ARAC FAMILY BMEI1383 10 None None None 17987131 Common - PROBABLE CARNITINE OPERON OXIDOREDUCTASE CAIA BMEI0848 84 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 17987767 Common - CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE BMEI1484 142 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 17987701 Common - GDP-mannose 4,6-dehydratase / GDP-4-amino-4,6-dideoxy-D-mannose formyltransferase BMEI1418 222 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 17986783 Common - SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE BMEI0500 58 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 17987021 Common - hypothetical protein BMEI0738 13 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 17986762 Common - translation-associated GTPase BMEI0479 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 17987334 Pathogen - hypothetical protein BMEI1051 2 None None None 17986820 Common - INTEGRASE/RECOMBINASE BMEI0537 19 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 17986330 Pathogen - hypothetical protein BMEI0046 1 None None None 17987231 Common - hypothetical protein BMEI0948 13 COG5373 COG5373, Predicted membrane protein Function unknown 17988116 Common - FRUCTOKINASE BMEI1833 74 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 17988065 Common - ENDONUCLEASE III BMEI1782 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 17987527 Common - TRANSPORTER, DME FAMILY BMEI1244 58 COG2510 COG2510, Predicted membrane protein Function unknown 17987568 Common recO DNA repair protein RecO BMEI1285 39 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 17988088 Common - VIRULENCE FACTOR MVIN BMEI1805 189 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 17986980 Common - TRANSPORTER, DME FAMILY BMEI0697 58 COG2510 COG2510, Predicted membrane protein Function unknown 17987428 Common - NADH dehydrogenase subunit N BMEI1145 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 17986504 Common - hypothetical protein BMEI0220 3 None None None 17987934 Common ureE urease accessory protein UreE BMEI1651 62 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 17988195 Common - SUGAR TRANSPORTER BMEI1912 7 None None None 17987303 Common - MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN A BMEI1020 71 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 17988036 Common - CYSQ PROTEIN BMEI1753 144 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 17987389 Common - PHNM PROTEIN BMEI1106 53 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 17987321 Common - PHENYLACETIC ACID DEGRADATION PROTEIN PAAD BMEI1038 147 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 17987437 Common - NADH dehydrogenase subunit E BMEI1154 154 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 17988166 Common frcK putative fructose transport system kinase BMEI1883 79 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 17987561 Pathogen - hypothetical protein BMEI1278 1 None None None 17987655 Common - CYANATE TRANSPORT PROTEIN CYNX BMEI1372 81 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 17987499 Common - Hypothetical Cytosolic Protein BMEI1216 8 COG4916 COG4916, Uncharacterized protein containing a TIR (Toll-Interleukin 1-resistance) domain Function unknown 17987068 Common - TRANSCRIPTIONAL REGULATORY PROTEIN BMEI0785 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 17986495 Common - hypothetical protein BMEI0211 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 17987243 Pathogen - hypothetical protein BMEI0960 1 None None None 17986979 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase BMEI0696 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 17986511 Common rpsP 30S ribosomal protein S16 BMEI0227 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 17988069 Common - NITROGEN REGULATORY IIA PROTEIN BMEI1786 139 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 17988319 Common - TRANSCRIPTIONAL REGULATORY PROTEIN CHVI BMEI2036 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 17986687 Common - hypothetical protein BMEI0404 10 None None None 17986871 Common - DNA REPAIR PROTEIN RECN BMEI0588 198 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 17987343 Common - OUTER MEMBRANE PROTEIN BMEI1060 100 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 17986411 Pathogen - hypothetical protein BMEI0127 2 None None None 17987036 Common - 30S ribosomal protein S7 BMEI0753 246 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 17986933 Pathogen - hypothetical protein BMEI0650 1 None None None 17986747 Common - lipid A-myristate beta-hydroxylase BMEI0464 32 COG3555 COG3555, Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases Posttranslational modification, protein turnover, chaperones 17986968 Common - TRANSCRIPTIONAL REGULATOR, ARAC FAMILY BMEI0685 144 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 17987459 Pathogen - hypothetical protein BMEI1176 2 None None None 17987851 Common - NITROGEN FIXATION PROTEIN FIXH BMEI1568 22 COG5456 COG5456, Predicted integral membrane protein linked to a cation pump Inorganic ion transport and metabolism 17987940 Common - hypothetical protein BMEI1657 17 None None None 17988335 Common - MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE A BMEI2052 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 17986986 Common cbiD cobalt-precorrin-6A synthase BMEI0703 80 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 17987789 Common - chorismate synthase BMEI1506 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 17987262 Common - GLUTAMINE SYNTHETASE BMEI0979 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 17986696 Common - PUTRESCINE TRANSPORT SYSTEM PERMEASE PROTEIN POTH BMEI0413 212 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 17988007 Common - hypothetical protein BMEI1724 11 COG5514 COG5514, Uncharacterized conserved protein Function unknown 17986540 Common - D-AMINO ACID DEHYDROGENASE SMALL SUBUNIT BMEI0256 131 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 17988047 Common - OXIDOREDUCTASE BMEI1764 54 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 161511160 Common - hypothetical protein BMEI0321 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 17988123 Common - SULFATE TRANSPORT SYSTEM PERMEASE PROTEIN CYST BMEI1840 238 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 17987396 Common - 3-oxoacyl-(acyl carrier protein) synthase II BMEI1113 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 17987111 Common - PHOSPHATIDATE CYTIDYLYLTRANSFERASE BMEI0828 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 17986509 Common - SIGNAL RECOGNITION PARTICLE, SUBUNIT FFH/SRP54 BMEI0225 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 17986369 Pathogen - hypothetical protein BMEI0085 2 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 17986425 Common - dihydrolipoamide acetyltransferase BMEI0141 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 17987693 Common - TRANSPOSASE BMEI1410 35 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17986740 Common - Hypothetical Membrane Associated Protein BMEI0457 35 COG5426 COG5426, Uncharacterized membrane protein Function unknown 17987791 Common - putative lipoprotein BMEI1508 43 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 17988297 Pathogen - Hypothetical Cytosolic Protein BMEI2014 2 None None None 17988314 Common - PHOSPHOCARRIER PROTEIN HPR BMEI2031 142 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 17988145 Common - 2'-5' RNA LIGASE BMEI1862 86 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 17987519 Pathogen - Hypothetical exported proline-rich protein BMEI1236 2 None None None 17987013 Common - LACTOYLGLUTATHIONE LYASE BMEI0730 123 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 17987727 Common - ADENINE-SPECIFIC METHYLTRANSFERASE BMEI1444 142 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 17986315 Common - Hypothetical Cytosolic Protein BMEI0031 34 COG3791 COG3791, Uncharacterized conserved protein Function unknown 17986634 Common - adenylosuccinate synthetase BMEI0351 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 17986961 Common - LOW PH-INDUCED PROTEIN A BMEI0678 55 COG0392 COG0392, Predicted integral membrane protein Function unknown 17986573 Common - Hypothetical Cytosolic Protein BMEI0290 41 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 17987730 Pathogen - hypothetical protein BMEI1447 2 None None None 17986827 Pathogen - hypothetical protein BMEI0544 2 None None None 17987308 Common - OUTER MEMBRANE PROTEIN E BMEI1025 42 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 17987718 Common - POLYSACCHARIDE DEACETYLASE BMEI1435 24 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 17987087 Common - 7-cyano-7-deazaguanine reductase BMEI0804 133 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 17988280 Common - GLUCONOLACTONASE BMEI1997 76 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 17987969 Pathogen - hypothetical protein BMEI1686 2 None None None 17987100 Common - BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE (ASYMMETRICAL) BMEI0817 236 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 17986299 Common - ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN BMEI0015 53 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 17987292 Pathogen - hypothetical protein BMEI1009 1 None None None 17987483 Common - DNA topoisomerase IV subunit A BMEI1200 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 17987613 Common - PROTEASE DO BMEI1330 224 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 17987574 Common - TRANSCRIPTIONAL REGULATOR, ARAC FAMILY BMEI1291 79 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 17987299 Common - FUMARATE HYDRATASE CLASS I, AEROBIC BMEI1016 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 17987524 Common purN phosphoribosylglycinamide formyltransferase BMEI1241 221 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 17987285 Common - TRANSPOSASE BMEI1002 72 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17988288 Common pheS phenylalanyl-tRNA synthetase subunit alpha BMEI2005 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 161511146 Common gltA type II citrate synthase BMEI0836 194 COG0372 GltA, Citrate synthase Energy production and conversion 161511158 Common - 2-isopropylmalate synthase BMEI0451 209 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 17987769 Common - DNA repair protein RadA BMEI1486 216 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 17987552 Common - CHLORAMPHENICOL-SENSITIVE PROTEIN RARD BMEI1269 96 COG2962 RarD, Predicted permeases General function prediction only 17986797 Pathogen - hypothetical protein BMEI0514 1 None None None 17987336 Common - TRANSPOSASE BMEI1053 72 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987470 Common ribH riboflavin synthase subunit beta BMEI1187 206 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 17987780 Common - HEMOLYSIN BMEI1497 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 161511137 Common - NADH dehydrogenase subunit H BMEI1151 190 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 17988251 Common - hypothetical protein BMEI1968 160 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 17988300 Common - N-(5'-phosphoribosyl)anthranilate isomerase BMEI2017 189 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 17986426 Common - Hypothetical Membrane Spanning Protein BMEI0142 18 COG3686 COG3686, Predicted membrane protein Function unknown 17987374 Common - HESB PROTEIN BMEI1091 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 17987489 Common - Hypothetical Cytosolic Protein BMEI1206 15 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 17986669 Common - SUCCINATE-SEMIALDEHYDE DEHYDROGENASE (NADP+) BMEI0386 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 17986663 Common - malate synthase G BMEI0380 83 COG2225 AceB, Malate synthase Energy production and conversion 17987739 Common - THIOL PEROXIDASE BMEI1456 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 17986644 Common - ABC TRANSPORTER ATP-BINDING PROTEIN / ABC TRANSPORTER PERMEASE PROTEIN BMEI0361 168 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 17986777 Common - TRANSCRIPTIONAL REGULATORY PROTEIN PETP BMEI0494 39 COG1846 MarR, Transcriptional regulators Transcription 17987219 Common - TrpR binding protein WrbA BMEI0936 99 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 17986528 Common - putative translaldolase BMEI0244 154 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 17987271 Common - DNA polymerase III subunit delta' BMEI0988 243 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 17986910 Common - hypothetical protein BMEI0627 6 None None None 17986558 Common - acetyl-CoA acetyltransferase BMEI0274 170 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 17987631 Pathogen - hypothetical protein BMEI1348 3 None None None 161511145 Common trpC indole-3-glycerol-phosphate synthase BMEI0843 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 17987009 Common glpX fructose 1,6-bisphosphatase II BMEI0726 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 17986551 Common - MEMBRANE PROTEIN MOSC BMEI0267 71 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 17987947 Common - Hypothetical Cytosolic Protein BMEI1664 20 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 17987535 Common - CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE BMEI1252 201 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 17986818 Pathogen - hypothetical protein BMEI0535 2 None None None 17986358 Common - hypothetical protein BMEI0074 30 COG1434 COG1434, Uncharacterized conserved protein Function unknown 17987403 Common - phosphotyrosyl phosphatase activator (PTPA) BMEI1120 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 161511151 Common rpsL 30S ribosomal protein S12 BMEI0752 240 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 17988218 Common - OLIGOPEPTIDE-BINDING PROTEIN APPA PRECURSOR BMEI1935 120 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 161511129 Common gmk guanylate kinase BMEI1469 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 17987444 Common - hypothetical protein BMEI1161 3 None None None 17987153 Common - hypothetical protein BMEI0870 3 None None None 17986412 Pathogen - hypothetical protein BMEI0128 3 None None None 17988107 Common - ATP-DEPENDENT RNA HELICASE DEAD BMEI1824 244 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 17987670 Common - xylose isomerase BMEI1387 72 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 17988075 Common - hypothetical protein BMEI1792 16 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 17986393 Common aspA aspartate ammonia-lyase BMEI0109 215 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 17988212 Pathogen - hypothetical protein BMEI1929 1 None None None 17986364 Common - histidinol-phosphate aminotransferase BMEI0080 239 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 17987640 Common - HISTIDINE PROTEIN KINASE DIVJ BMEI1357 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 17988261 Common - RIBOSOMAL-PROTEIN-ALANINE ACETYLTRANSFERASE BMEI1978 180 COG0456 RimI, Acetyltransferases General function prediction only 17986442 Common - ACETYLTRANSFERASE BMEI0158 10 COG0456 RimI, Acetyltransferases General function prediction only 17987837 Common - TRANSPORTER, MFS superfamily BMEI1554 9 None None None 17987362 Common - LIPOPROTEIN NLPD BMEI1079 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 17987899 Common - 2'-deoxycytidine 5'-triphosphate deaminase BMEI1616 23 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 17987464 Common - fatty acid/phospholipid synthesis protein BMEI1181 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 17987879 Common - LrgB protein BMEI1596 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 17987531 Common - GLUTATHIONE S-TRANSFERASE BMEI1248 67 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 17988096 Common - hypothetical protein BMEI1813 3 None None None 17986405 Common secA preprotein translocase subunit SecA BMEI0121 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 17987311 Common - hypothetical protein BMEI1028 15 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 17987408 Common - MALEYLPYRUVATE ISOMERASE BMEI1125 101 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 17987596 Common - Hypothetical Cytosolic Protein BMEI1313 20 None None None 17987816 Common - hypothetical protein BMEI1533 22 None None None 17987594 Common - hypothetical protein BMEI1311 9 None None None 17986549 Common - LEUCINE-, ISOLEUCINE-, VALINE-, THREONINE-, AND ALANINE-BINDING PROTEIN PRECURSOR BMEI0265 109 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 17987890 Common - GLYCEROL METABOLISM ACTIVATOR BMEI1607 176 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 17987801 Common ubiA prenyltransferase BMEI1518 178 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 17987798 Common - 17 KD COMMON-ANTIGEN BMEI1515 7 None None None 161511152 Common rplJ 50S ribosomal protein L10 BMEI0747 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 17987163 Common - SINGLE-STRAND BINDING PROTEIN BMEI0880 211 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 17986373 Common - RIBONUCLEASE BN BMEI0089 67 COG1295 Rbn, Predicted membrane protein Function unknown 17987178 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, LYSR FAMILY BMEI0895 17 COG0583 LysR, Transcriptional regulator Transcription 17988054 Common - coproporphyrinogen III oxidase BMEI1771 216 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 17987915 Common - acyl-CoA synthetase BMEI1632 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 17988164 Pathogen - hypothetical protein BMEI1881 2 None None None 17986389 Common - L-ASPARAGINASE II BMEI0105 116 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 17987194 Common - NIFU PROTEIN BMEI0911 89 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 17986909 Common - TRANSCRIPTIONAL REGULATOR, GNTR FAMILY / MULTIPLE SUBSTRATE AMINOTRANSFERASE BMEI0626 226 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 17986756 Common - UBIQUINOL-CYTOCHROME C REDUCTASE IRON-SULFUR SUBUNIT BMEI0473 100 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 17986718 Common - DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DPPB BMEI0435 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 17987962 Pathogen - hypothetical protein BMEI1679 1 None None None 17987426 Common - METAL DEPENDENT HYDROLASE BMEI1143 155 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 17987352 Common tig trigger factor BMEI1069 214 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 17987367 Common tatA twin argininte translocase protein A BMEI1084 105 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 17987355 Common - hypothetical protein BMEI1072 7 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 17986894 Common - HFLC PROTEIN BMEI0611 120 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 17986502 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, LYSR FAMILY BMEI0218 109 COG0583 LysR, Transcriptional regulator Transcription 17988125 Common - hypothetical protein BMEI1842 8 COG1434 COG1434, Uncharacterized conserved protein Function unknown 17986382 Pathogen - hypothetical protein BMEI0098 1 None None None 17987520 Common - UDP-GLUCOSE 4-EPIMERASE BMEI1237 132 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 17987668 Common - LACI-FAMILY TRANSCRIPTION REGULATOR BMEI1385 97 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 17987650 Common - SUPEROXIDE DISMUTASE (MN) BMEI1367 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 17988223 Common - molybdopterin biosynthesis protein MoeB BMEI1940 218 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 17986347 Pathogen - Hypothetical Membrane Spanning Protein BMEI0063 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 17986655 Common - two-component response regulator BMEI0372 126 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 17988153 Common - argininosuccinate synthase BMEI1870 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 17986685 Common - 31 KDA OUTER-MEMBRANE IMMUNOGENIC PROTEIN PRECURSOR BMEI0402 28 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 17986857 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase BMEI0574 211 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 17987199 Common - hypothetical protein BMEI0916 13 None None None 17987547 Common - ORGANIC SOLVENT TOLERANCE PROTEIN BMEI1264 116 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 17987211 Common - ACETATE COA-TRANSFERASE ALPHA SUBUNIT BMEI0928 96 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 17986476 Common - METHYLTRANSFERASE BMEI0192 222 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 17986523 Common - USG PROTEIN BMEI0239 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 17988268 Common - PHOSPHATE TRANSPORT SYSTEM PROTEIN PHOU BMEI1985 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 17986889 Common - BICYCLOMYCIN RESISTANCE PROTEIN HOMOLOG BMEI0606 16 None None None 17987618 Common - 17 KD SURFACE ANTIGEN PRECURSOR BMEI1335 19 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 17986678 Common - 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE BMEI0395 208 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17988321 Common - hypothetical protein BMEI2038 109 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 17987815 Common - FARNESYL PYROPHOSPHATE SYNTHETASE / GERANYLTRANSTRANSFERASE BMEI1532 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 17988023 Common - ALDEHYDE DEHYDROGENASE BMEI1740 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 17986707 Common - hypothetical protein BMEI0424 30 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 17986621 Common - hypothetical protein BMEI0338 17 None None None 17986356 Common - CELL DIVISION ATP-BINDING PROTEIN FTSE BMEI0072 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 17986833 Common - hypothetical protein BMEI0550 18 COG3822 COG3822, ABC-type sugar transport system, auxiliary component General function prediction only 17986586 Common - Hypothetical Cytosolic Protein BMEI0303 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 17987932 Common - UREASE ACCESSORY PROTEIN UREG BMEI1649 152 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 17988298 Common - zinc metallopeptidase BMEI2015 150 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 17986339 Common - hypothetical protein BMEI0055 15 None None None 17986700 Common - NON-MOTILE AND PHAGE-RESISTANCE PROTEIN BMEI0417 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 17986650 Common - hypothetical protein BMEI0367 22 None None None 17986491 Common - gamma-glutamyl kinase BMEI0207 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 17987379 Common - SUCCINOGLYCAN BIOSYNTHESIS PROTEIN EXOI BMEI1096 59 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 17987609 Common - LPSA PROTEIN BMEI1326 22 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 17987904 Common argD bifunctional N-succinyldiaminopimelate-aminotransferase/acetylornithine transaminase protein BMEI1621 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 17986304 Common - GLUCOSE-FRUCTOSE OXIDOREDUCTASE PRECURSOR BMEI0020 183 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 17987104 Common - hypothetical protein BMEI0821 19 None None None 17988114 Common - PENICILLIN-BINDING PROTEIN 1A BMEI1831 201 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 17986615 Common ruvC Holliday junction resolvase BMEI0332 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 17988028 Common - hypothetical protein BMEI1745 42 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 17987133 Common - 2-dehydro-3-deoxyphosphooctonate aldolase BMEI0850 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 17986454 Common - TRANSPORTER, DME FAMILY BMEI0170 71 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 17987081 Common - hypothetical protein BMEI0798 6 None None None 17986323 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha BMEI0039 180 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 17986539 Pathogen - hypothetical protein BMEI0255 1 None None None 17987654 Common - hypothetical protein BMEI1371 11 None None None 17987939 Pathogen - hypothetical protein BMEI1656 1 None None None 17986958 Common - SULFATE TRANSPORT SYSTEM PERMEASE PROTEIN CYSW BMEI0675 215 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 17987629 Common - hypothetical protein BMEI1346 14 None None None 17987090 Pathogen - hypothetical protein BMEI0807 2 None None None 17988086 Common - NADP-DEPENDENT MALIC ENZYME BMEI1803 153 COG0280 Pta, Phosphotransacetylase Energy production and conversion 17987301 Common - PHOSPHORIBOSYLFORMIMINO-5-AMINOIMIDAZOLE CARBOXAMIDE RIBOTIDE ISOMERASE BMEI1018 50 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 17987323 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI1040 180 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 17987144 Common - GLUCOSE 1-DEHYDROGENASE II BMEI0861 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17987943 Common - hypothetical protein BMEI1660 4 None None None 17986608 Common - MotA/TolQ/ExbB proton channel family BMEI0325 28 None None None 17986939 Common - DAUNORUBICIN RESISTANCE TRANSMEMBRANE PROTEIN BMEI0656 119 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 17987611 Common - Sensory Transduction Histidine Kinase BMEI1328 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 17987756 Common - 3-oxoacyl-(acyl carrier protein) synthase II BMEI1473 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 17987917 Common - PHOSPHOGLYCOLATE PHOSPHATASE BMEI1634 140 COG0546 Gph, Predicted phosphatases General function prediction only 17987967 Pathogen - hypothetical protein BMEI1684 1 None None None 17987888 Common - LARGE CONDUCTANCE MECHANOSENSITIVE CHANNEL BMEI1605 107 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 17987544 Common - leucyl aminopeptidase BMEI1261 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 17987954 Common infA translation initiation factor IF-1 BMEI1671 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 17986575 Common - pyruvate kinase BMEI0292 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 17987910 Common - ARGININE-BINDING PERIPLASMIC PROTEIN BMEI1627 101 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 17986301 Common - ALKANAL MONOOXYGENASE ALPHA CHAIN BMEI0017 64 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 17986721 Common - DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DPPF BMEI0438 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 17988302 Common trpA tryptophan synthase subunit alpha BMEI2019 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 17987861 Common - hypothetical protein BMEI1578 33 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 17987435 Common - NADH dehydrogenase subunit G BMEI1152 190 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 17986530 Common - PRIMOSOMAL PROTEIN N' BMEI0246 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 17988276 Common - hypothetical protein BMEI1993 22 COG3672 COG3672, Predicted periplasmic protein Function unknown 17987450 Common - hypothetical protein BMEI1167 37 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 17986786 Common - ACYL-COA HYDROLASE BMEI0503 113 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 17987410 Common - phosphoribosylformylglycinamidine synthase II BMEI1127 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 17988239 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase BMEI1956 83 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 17986378 Common - VACUOLAR ATP SYNTHASE 16 KD PROTEOLIPID SUBUNIT BMEI0094 99 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 161511148 Common tsf elongation factor Ts BMEI0824 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 17987881 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, LYSR FAMILY BMEI1598 174 COG0583 LysR, Transcriptional regulator Transcription 17987010 Common - D-ALANINE--D-ALANINE LIGASE A BMEI0727 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 17987733 Common - threonine synthase BMEI1450 179 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 17986488 Common - ACETYLTRANSFERASE BMEI0204 22 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 17987584 Common dapA dihydrodipicolinate synthase BMEI1301 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 17986996 Common - precorrin-2 C(20)-methyltransferase BMEI0713 185 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 17986632 Common - D-3-PHOSPHOGLYCERATE DEHYDROGENASE BMEI0349 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 17988009 Common - GLYCINE BETAINE/L-PROLINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW BMEI1726 127 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 17986953 Common - Putative membrane-associated alkaline phosphatase BMEI0670 83 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 17987226 Common - ribonucleotide-diphosphate reductase subunit alpha BMEI0943 181 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 17987095 Common - hypothetical protein BMEI0812 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 17987586 Common - Hypothetical Cytosolic Protein BMEI1303 25 COG3743 COG3743, Uncharacterized conserved protein Function unknown 17987622 Common - hypothetical protein BMEI1339 3 None None None 17987659 Common - DEATH ON CURING PROTEIN BMEI1376 64 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 17987677 Common - MANNOSE-6-PHOSPHATE ISOMERASE BMEI1394 34 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 17986846 Pathogen - hypothetical protein BMEI0563 2 None None None 17987703 Common - TRANSPOSASE BMEI1420 87 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987113 Common - OUTER MEMBRANE PROTEIN BMEI0830 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 17988011 Common - GLYCINE BETAINE/L-PROLINE TRANSPORT SYSTEM PERMEASE PROTEIN PROW BMEI1728 153 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 17987854 Common - guanine deaminase BMEI1571 167 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 17988139 Common - hypothetical protein BMEI1856 33 COG5429 COG5429, Uncharacterized secreted protein Function unknown 17986821 Pathogen - hypothetical protein BMEI0538 1 None None None 17987976 Pathogen - hypothetical protein BMEI1693 1 None None None 17986565 Common - ZINC METALLOPROTEASE BMEI0282 131 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 17986680 Common - DIHYDROXYACETONE KINASE BMEI0397 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 17987476 Common - cell wall degradation protein BMEI1193 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 17986943 Common - METAL CHELATE TRANSPORT ATP-BINDING PROTEIN BMEI0660 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 161511134 Common - AMP nucleosidase BMEI1318 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 17986873 Common - hypothetical protein BMEI0590 35 COG5587 COG5587, Uncharacterized conserved protein Function unknown 17987715 Common - HYDROXYACYLGLUTATHIONE HYDROLASE BMEI1432 144 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 17987795 Common - enoyl-(acyl carrier protein) reductase BMEI1512 222 COG0623 FabI, Enoyl- acyl-carrier-protein 17987028 Common rplK 50S ribosomal protein L11 BMEI0745 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 17988229 Common - formamidopyrimidine-DNA glycosylase BMEI1946 178 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 17986645 Common - hypothetical protein BMEI0362 22 COG3698 COG3698, Predicted periplasmic protein Function unknown 17986444 Common - SUCCINATE DEHYDROGENASE HYDROPHOBIC MEMBRANE ANCHOR PROTEIN BMEI0160 44 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 17987290 Common - 25 KDA OUTER-MEMBRANE IMMUNOGENIC PROTEIN PRECURSOR BMEI1007 29 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 17987045 Common rplV 50S ribosomal protein L22 BMEI0762 216 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 17987729 Common - PHOSPHOGLYCOLATE PHOSPHATASE BMEI1446 154 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 17986865 Common ddl D-alanine--D-alanine ligase BMEI0582 211 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 17987297 Common - cell wall degradation protein BMEI1014 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 17987306 Common - GLUTATHIONE S-TRANSFERASE III BMEI1023 33 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 17986430 Common - hypothetical protein BMEI0146 45 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 17987189 Pathogen - hypothetical protein BMEI0906 1 None None None 17987782 Common - PIRIN BMEI1499 144 COG1741 COG1741, Pirin-related protein General function prediction only 17987510 Common - hypothetical protein BMEI1227 13 None None None 17987079 Common - 31 KDA IMMUNOGENIC PROTEIN PRECURSOR BMEI0796 92 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 17987250 Common - malic enzyme BMEI0967 214 COG0281 SfcA, Malic enzyme Energy production and conversion 17987485 Common aspS aspartyl-tRNA synthetase BMEI1202 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 17986735 Common - putative phosphohydrolase, Icc family BMEI0452 43 COG1409 Icc, Predicted phosphohydrolases General function prediction only 17987974 Common - Hypothetical Membrane Spanning Protein BMEI1691 3 None None None 17987446 Common - TRANSPOSASE BMEI1163 23 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987264 Common - PHOSPHOGLYCOLATE PHOSPHATASE BMEI0981 145 COG0546 Gph, Predicted phosphatases General function prediction only 17988286 Common - TRANS-1,2-DIHYDROBENZENE-1,2-DIOL DEHYDROGENASE / D-xylose 1-dehydrogenase (NADP+) BMEI2003 164 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 17987830 Common - ATP SYNTHASE BMEI1547 25 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 17986553 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase BMEI0269 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 17986999 Common - PRECORRIN-6Y C5,15-METHYLTRANSFERASE (DECARBOXYLATING) BMEI0716 105 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 17986630 Common - phosphoserine aminotransferase BMEI0347 68 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 17987316 Common - hypothetical protein BMEI1033 5 None None None 17986547 Common - LEUCINE-, ISOLEUCINE-, VALINE-, THREONINE-, AND ALANINE-BINDING PROTEIN PRECURSOR BMEI0263 140 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 17986316 Common - 3-OXOACYL-(ACYL-CARRIER PROTEIN) REDUCTASE BMEI0032 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17987110 Common - UNDECAPRENYL PYROPHOSPHATE SYNTHETASE BMEI0827 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 17987318 Common - ATP-DEPENDENT RNA HELICASE DEAD BMEI1035 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 17986395 Common - ASPARAGINE TRANSPORT ATP-BINDING PROTEIN BMEI0111 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 17987257 Common - ribose-5-phosphate isomerase A BMEI0974 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 17987983 Common - hypothetical protein BMEI1700 4 COG3311 AlpA, Predicted transcriptional regulator Transcription 17987376 Common - EXODEOXYRIBONUCLEASE III BMEI1093 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 17988337 Common fxsA FxsA BMEI2054 69 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 17986874 Common - XAA-PRO AMINOPEPTIDASE BMEI0591 236 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 17986537 Common - TRANSCRIPTIONAL REGULATOR, MARR FAMILY BMEI0253 106 COG1846 MarR, Transcriptional regulators Transcription 17987624 Common - Phage Host Specificity Protein BMEI1341 25 None None None 17987380 Common - Uracil-DNA glycosylase BMEI1097 56 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 17986966 Common - hypothetical protein BMEI0683 6 None None None 17986698 Common - hypothetical protein BMEI0415 25 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 17986906 Common - TRANSCRIPTIONAL REGULATOR, TETR FAMILY BMEI0623 21 COG1309 AcrR, Transcriptional regulator Transcription 17986931 Common ureB urease subunit beta BMEI0648 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 17987847 Common - CYTOCHROME C OXIDASE POLYPEPTIDE I HOMOLOG, BACTEROID BMEI1564 137 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 17987749 Common - CYTOCHROME C OXIDASE POLYPEPTIDE II BMEI1466 144 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 17988201 Common - Hypothetical Cytosolic Protein BMEI1918 17 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 17986984 Common - PRECORRIN-4 C11-METHYLTRANSFERASE BMEI0701 198 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 17987765 Common - hypothetical protein BMEI1482 12 None None None 17987394 Common - acyl carrier protein BMEI1111 97 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 17988316 Pathogen - hypothetical protein BMEI2033 1 None None None 17987433 Common - NADH dehydrogenase subunit I BMEI1150 195 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 17988057 Pathogen - LACTOYLGLUTATHIONE LYASE, PUTATIVE BMEI1774 2 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 17987278 Common - SECRETION ACTIVATOR PROTEIN BMEI0995 35 COG3926 zliS, Putative secretion activating protein General function prediction only 17988174 Pathogen - hypothetical protein BMEI1891 1 None None None 17986858 Common - UDP-N-ACETYLMURAMOYLALANYL-D-GLUTAMYL-2,6-DIAMINOPIMELATE--D-ALANYL-D- ALANYL LIGASE BMEI0575 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 17987867 Common - INVASION PROTEIN B BMEI1584 19 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 17988143 Common - hypothetical transmembrane oxidoreductase BMEI1860 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 17988130 Pathogen - hypothetical protein BMEI1847 2 None None None 17986792 Common - LIPOPOLYSACCHARIDE CORE BIOSYNTHESIS MANNOSYLTRANSFERASE LPCC BMEI0509 207 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 17986805 Common carB carbamoyl phosphate synthase large subunit BMEI0522 232 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 17988063 Pathogen - hypothetical protein BMEI1780 1 None None None 17986423 Common - succinyl-CoA synthetase subunit alpha BMEI0139 214 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 17988045 Common - O-6-METHYLGUANINE-DNA-ALKYLTRANSFERASE BMEI1762 217 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 17987341 Common - ASPARTATE AMINOTRANSFERASE BMEI1058 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 17987793 Common - COLD SHOCK PROTEIN CSPA BMEI1510 176 COG1278 CspC, Cold shock proteins Transcription 17987823 Common - GLYCOSYLTRANSFERASE BMEI1540 15 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 17987808 Common - Helix-turn-helix protein, copG family BMEI1525 4 COG3905 COG3905, Predicted transcriptional regulator Transcription 17987671 Common - OXIDOREDUCTASE BMEI1388 128 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 17987176 Common - ACRIFLAVIN RESISTANCE PROTEIN B BMEI0893 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 17987642 Common - SufE protein probably involved in Fe-S center assembly BMEI1359 100 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 17986403 Common - hypothetical protein BMEI0119 19 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 17988094 Common - ACID TOLERANCE REGULATORY PROTEIN ACTR BMEI1811 218 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 17986297 Common - ABC TRANSPORTER INTEGRAL MEMBRANE PROTEIN BMEI0013 105 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 17987570 Common rncS ribonuclease III BMEI1287 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 17987256 Common - hypothetical protein BMEI0973 14 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 17987165 Common - PHOSPHONATES TRANSPORT ATP-BINDING PROTEIN PHNN BMEI0882 76 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 17988258 Common - PHOH PROTEIN BMEI1975 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 17986771 Common - prolipoprotein diacylglyceryl transferase BMEI0488 206 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 17988035 Common - TRANSCRIPTION REGULATOR, CRP FAMILY BMEI1752 98 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 17988266 Common - SPORE-CORTEX-LYTIC ENZYME PREPEPTIDE PRECURSOR BMEI1983 23 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 17986711 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase BMEI0428 218 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 161511154 Common ccrB camphor resistance protein CrcB BMEI0633 116 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 161511164 Common prfA peptide chain release factor 1 BMEI0191 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 17987072 Common alaS alanyl-tRNA synthetase BMEI0789 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 17987592 Common - HISTIDINOL-PHOSPHATE AMINOTRANSFERASE BMEI1309 191 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 17986460 Common hemC porphobilinogen deaminase BMEI0176 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 17987401 Common - BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE III BMEI1118 41 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 17987893 Common - Hypothetical Cytosolic Protein BMEI1610 44 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 17987877 Common - hypothetical protein BMEI1594 24 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 17987406 Common - phosphoribosylformylglycinamidine synthase subunit PurS BMEI1123 117 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 17986325 Pathogen - hypothetical protein BMEI0041 2 None None None 17987496 Common - cystathionine beta-lyase BMEI1213 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 161511120 Common rpsA 30S ribosomal protein S1 BMEI1915 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 17987156 Common - GTP-BINDING PROTEIN HFLX BMEI0873 216 COG2262 HflX, GTPases General function prediction only 17987732 Common - hypothetical protein BMEI1449 10 None None None 17987283 Common - hypothetical protein BMEI1000 4 None None None 17987015 Common - Hypothetical Cytosolic Protein BMEI0732 87 COG1430 COG1430, Uncharacterized conserved protein Function unknown 17986371 Common - THIOL:DISULFIDE INTERCHANGE PROTEIN TLPA BMEI0087 138 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 17988016 Common - THIAMINE BIOSYNTHESIS OXIDOREDUCTASE THIO BMEI1733 90 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 17987216 Common - cysteine synthase A BMEI0933 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 17986779 Common - HYDROXYACYLGLUTATHIONE HYDROLASE BMEI0496 218 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 17987504 Common - Hypothetical Cytosolic Protein BMEI1221 6 None None None 17988104 Common - hypothetical protein BMEI1821 40 COG4291 COG4291, Predicted membrane protein Function unknown 17986588 Common - TRANSCRIPTIONAL REGULATOR, DEOR FAMILY BMEI0305 88 COG2378 COG2378, Predicted transcriptional regulator Transcription 17988073 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI1790 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 17987604 Common - DNA POLYMERASE, BACTERIOPHAGE-TYPE BMEI1321 154 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 17987925 Common - TRANSCRIPTIONAL REGULATOR, TETR FAMILY BMEI1642 21 COG1309 AcrR, Transcriptional regulator Transcription 17987007 Common - aminotransferase BMEI0724 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 17987945 Pathogen - hypothetical protein BMEI1662 1 None None None 17986912 Common - hypothetical protein BMEI0629 11 None None None 17988105 Common - S-FORMYLGLUTATHIONE HYDROLASE BMEI1822 96 COG0627 COG0627, Predicted esterase General function prediction only 17986390 Common - TRANSCRIPTIONAL REGULATOR, GNTR FAMILY BMEI0106 129 COG1802 GntR, Transcriptional regulators Transcription 17986800 Common - GLUTATHIONE S-TRANSFERASE BMEI0517 101 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 17986945 Common - D-RIBOSE-BINDING PERIPLASMIC PROTEIN PRECURSOR BMEI0662 38 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 161511123 Common - sulfate adenylyltransferase subunit 2 BMEI1755 130 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 17987720 Common - PUTATIVE HYDROXLASE BMEI1437 30 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 17986836 Common - putative ABC transporter ATP-binding protein BMEI0553 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 17986351 Common - CAMP-DEPENDENT PROTEIN KINASE REGULATORY SUBUNIT BMEI0067 49 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 17986595 Common - Hypothetical Cytosolic Protein BMEI0312 7 None None None 17988197 Common - Hypothetical Membrane Spanning Protein BMEI1914 114 COG2855 COG2855, Predicted membrane protein Function unknown 17987579 Common - GUANOSINE-3',5'-BIS(DIPHOSPHATE) 3'-PYROPHOSPHOHYDROLASE BMEI1296 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 17987050 Common rplN 50S ribosomal protein L14 BMEI0767 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 17987633 Common - Phage DNA Packaging Protein BMEI1350 25 COG5323 COG5323, Uncharacterized conserved protein Function unknown 17987686 Common - TRANSPOSASE BMEI1403 72 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987776 Common - peptidoglycan binding protein (LysM domain) BMEI1493 45 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 17986362 Common - hypothetical protein BMEI0078 11 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 17987217 Common - ATP-DEPENDENT RNA HELICASE RHLE BMEI0934 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 17986439 Common - PUTATIVE ALLANTOIN PERMEASE BMEI0155 48 COG1953 FUI1, Cytosine/uracil/thiamine/allantoin permeases Nucleotide transport and metabolism / Coenzyme metabolism 17986816 Common - Hypothetical Cytosolic Protein BMEI0533 15 COG5453 COG5453, Uncharacterized conserved protein Function unknown 17986787 Common - EXTENSIN-LIKE PROTEIN BMEI0504 36 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 17986516 Common - TRANSPORTER BMEI0232 72 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 17987978 Pathogen - hypothetical protein BMEI1695 1 None None None 17987745 Common - CYTOCHROME C OXIDASE POLYPEPTIDE III BMEI1462 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 17986715 Common - hypothetical protein BMEI0432 8 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 17988119 Common - nicotinate phosphoribosyltransferase BMEI1836 60 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 17986830 Common - PHNA PROTEIN BMEI0547 105 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 17986422 Common sucC succinyl-CoA synthetase subunit beta BMEI0138 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 17986494 Common - iojap protein family BMEI0210 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 161511125 Common - ornithine carbamoyltransferase BMEI1620 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 17988085 Common - NADP-DEPENDENT MALIC ENZYME BMEI1802 199 COG0281 SfcA, Malic enzyme Energy production and conversion 17986568 Common tbpA thiamin transporter substrate binding subunit BMEI0285 62 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 17988188 Common - prephenate dehydratase BMEI1905 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 17988169 Common - phosphoglucomutase BMEI1886 193 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 17987644 Common - Hypothetical Cytosolic Protein BMEI1361 20 None None None 17986470 Common - Hypothetical Cytosolic Protein BMEI0186 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 17987204 Common - UDP-GLUCOSE 4-EPIMERASE BMEI0921 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 17986709 Common - ACETYLTRANSFERASE BMEI0426 29 COG2388 COG2388, Predicted acetyltransferase General function prediction only 17988190 Common - HIT1 PROTEIN BMEI1907 52 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 17988013 Common - COPPER-TRANSPORTING ATPASE BMEI1730 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 17986377 Common - EXSD PROTEIN BMEI0093 109 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 17988092 Common - PROTEIN YBIS PRECURSOR BMEI1809 77 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 17987011 Common - SINGLE-STRANDED-DNA-SPECIFIC EXONUCLEASE RECJ BMEI0728 195 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 17987395 Common - 3-oxoacyl-(acyl carrier protein) synthase II BMEI1112 168 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 17987002 Common - methionine aminopeptidase BMEI0719 243 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 17988200 Common - 3-phosphoshikimate 1-carboxyvinyltransferase BMEI1917 231 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 17987042 Common rplW 50S ribosomal protein L23 BMEI0759 230 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 17986875 Common prmA ribosomal protein L11 methyltransferase BMEI0592 156 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 17987502 Pathogen - hypothetical protein BMEI1219 1 None None None 17986500 Pathogen - hypothetical protein BMEI0216 2 COG2261 COG2261, Predicted membrane protein Function unknown 17987200 Common - Nitroreductase family BMEI0917 20 COG0778 NfnB, Nitroreductase Energy production and conversion 17987616 Common - cytochrome c-type biogenesis protein CcmE BMEI1333 94 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 17986970 Pathogen - hypothetical protein BMEI0687 2 COG5510 COG5510, Predicted small secreted protein Function unknown 17987385 Common - TRANSPORTER BMEI1102 53 COG3577 COG3577, Predicted aspartyl protease General function prediction only 17987240 Common - hypothetical protein BMEI0957 8 COG5661 COG5661, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 17987763 Common rpsF 30S ribosomal protein S6 BMEI1480 198 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 17988199 Common cmk cytidylate kinase BMEI1916 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 17986937 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI0654 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 17987092 Common - hypothetical protein BMEI0809 15 COG3503 COG3503, Predicted membrane protein Function unknown 17987147 Common - NITROGEN REGULATION PROTEIN NIFR3 BMEI0864 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 17986370 Common - argininosuccinate lyase BMEI0086 235 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 17988162 Common - Hypothetical Cytosolic Protein BMEI1879 3 None None None 17987959 Pathogen - hypothetical protein BMEI1676 1 None None None 17987495 Common - PHOSPHATIDYLGLYCEROPHOSPHATASE B BMEI1212 64 None None None 17986661 Common - RNA polymerase factor sigma-32 BMEI0378 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 17987588 Common - PORIN BMEI1305 13 None None None 17986317 Common - N-ACYL-L-AMINO ACID AMIDOHYDROLASE BMEI0033 163 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 17987924 Common - TRANSCRIPTIONAL REGULATOR, TETR FAMILY BMEI1641 37 None None None 17986657 Common - SENSORY TRANSDUCTION HISTIDINE KINASE BMEI0374 37 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 17988210 Common - ENOYL-COA HYDRATASE BMEI1927 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 17986461 Common - uroporphyrinogen-III synthase BMEI0177 27 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 17988234 Common - PUTATIVE HYDROLASE BMEI1951 168 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 17987247 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI0964 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 17987246 Common - TOLUENE TOLERANCE PROTEIN TTG2C BMEI0963 68 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 17986349 Common - Hypothetical Cytosolic Protein BMEI0065 37 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 17986907 Common - ketol-acid reductoisomerase BMEI0624 212 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 17986667 Common - DISULFIDE BOND FORMATION PROTEIN B BMEI0384 37 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 17987950 Common - Hypothetical Cytosolic Protein BMEI1667 22 None None None 17986285 Common hemE uroporphyrinogen decarboxylase BMEI0001 177 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 17986835 Common - LYSOPHOSPHOLIPASE L2 BMEI0552 81 COG2267 PldB, Lysophospholipase Lipid metabolism 17986451 Common - AMMONIUM TRANSPORTER BMEI0167 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 17987906 Common - hypothetical protein BMEI1623 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 17986728 Common - OXALATE/FORMATE ANTIPORTER BMEI0445 100 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 161511133 Common - amidase BMEI1360 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 17988050 Common - hypothetical protein BMEI1767 10 None None None 17987522 Common - PERMEASE BMEI1239 120 COG0628 PerM, Predicted permease General function prediction only 17986613 Common - OPGC BMEI0330 32 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 17986964 Pathogen - hypothetical protein BMEI0681 2 None None None 17987637 Common - Hypothetical Cytosolic Protein BMEI1354 6 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 17987994 Common - hypothetical protein BMEI1711 34 COG3254 COG3254, Uncharacterized conserved protein Function unknown 17988292 Common - NICKEL-COBALT-CADMIUM RESISTANCE PROTEIN NCCN BMEI2009 42 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 17986705 Common - hypothetical protein BMEI0422 14 None None None 17988327 Common - Hypothetical Membrane Spanning Protein BMEI2044 10 None None None 17987412 Common - GLUTAREDOXIN BMEI1129 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 17988025 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI1742 112 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 17986306 Common - 3-HYDROXYBUTYRYL-COA DEHYDRATASE BMEI0022 153 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 17987075 Common - INTRACELLULAR PROTEINASE I BMEI0792 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 17986677 Common - 2-DEOXY-D-GLUCONATE 3-DEHYDROGENASE BMEI0394 179 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 17986670 Common - TRANSCRIPTIONAL REGULATOR, ICLR FAMILY BMEI0387 101 COG1414 IclR, Transcriptional regulator Transcription 17987340 Common - RIBONUCLEASE E / ZINC METALLOPROTEASE BMEI1057 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 17987234 Common - amino acid regulated cytosolic protein BMEI0951 42 COG3106 COG3106, Predicted ATPase General function prediction only 17987970 Pathogen - hypothetical protein BMEI1687 1 None None None 17988172 Common - hypothetical protein BMEI1889 5 None None None 17986746 Common - POLY(A) POLYMERASE / TRNA NUCLEOTIDYLTRANSFERASE BMEI0463 202 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 17986886 Common - hypothetical protein BMEI0603 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 17987097 Common - PENICILLIN-BINDING PROTEIN 6 (D-ALANYL-D-ALANINE CARBOXYPEPTIDASE FRACTION C) BMEI0814 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 17988132 Common - THIOL:DISULFIDE INTERCHANGE PROTEIN CYCY PRECURSOR BMEI1849 150 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 17988149 Common - hypothetical protein BMEI1866 30 None None None 17987564 Common - dihydroorotase BMEI1281 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 17986823 Pathogen - hypothetical protein BMEI0540 1 None None None 17988278 Common - MG(2+) CHELATASE FAMILY PROTEIN BMEI1995 187 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 17986536 Common atpC F0F1 ATP synthase subunit epsilon BMEI0252 167 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 17986332 Pathogen - hypothetical protein BMEI0048 1 None None None 17986684 Common - hypothetical protein BMEI0401 16 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 17988216 Pathogen - hypothetical protein BMEI1933 1 None None None 17987031 Common rplL 50S ribosomal protein L7/L12 BMEI0748 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 17987692 Common - TRANSPOSASE BMEI1409 23 None None None 17986606 Common - PROBABLE TRANSPORT ATP-BINDING PROTEIN MSBA BMEI0323 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 17986341 Common - Hypothetical Membrane Spanning Protein BMEI0057 57 COG1738 COG1738, Uncharacterized conserved protein Function unknown 161511155 Common - NAD(FAD)-utilizing dehydrogenase BMEI0614 137 COG2081 COG2081, Predicted flavoproteins General function prediction only 17986640 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, ASNC FAMILY BMEI0357 155 COG1522 Lrp, Transcriptional regulators Transcription 17987440 Common - NADH dehydrogenase subunit B BMEI1157 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 17986851 Common - hypothetical protein BMEI0568 2 None None None 17988159 Common dnaE2 error-prone DNA polymerase BMEI1876 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 17987354 Common - Hypothetical Membrane Spanning Protein BMEI1071 8 COG4872 COG4872, Predicted membrane protein Function unknown 17986295 Common holA DNA polymerase III subunit delta BMEI0011 69 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 17987628 Common - Phage MINOR TAIL PROTEIN H BMEI1345 14 COG5281 COG5281, Phage-related minor tail protein Function unknown 17986384 Common - hypothetical protein BMEI0100 3 None None None 17986583 Common - TRANSPORTER, MFS superfamily BMEI0300 60 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 17987282 Pathogen - hypothetical protein BMEI0999 2 None None None 17987368 Common - Hypothetical Cytosolic Protein BMEI1085 141 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 17987305 Common - ARGININE/ORNITHINE-BINDING PERIPLASMIC PROTEIN PRECURSOR BMEI1022 172 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 17986896 Common - PROTEASE DO BMEI0613 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 17988271 Common - PHOSPHATE TRANSPORT SYSTEM PERMEASE PROTEIN PSTC BMEI1988 230 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 17986971 Common - 3-HYDROXYISOBUTYRATE DEHYDROGENASE BMEI0688 163 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 17986733 Common - COBALT-ZINC-CADMIUM RESISTANCE PROTEIN CZCD BMEI0450 215 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 17986578 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit BMEI0295 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 17987960 Pathogen - hypothetical protein BMEI1677 1 None None None 17987188 Pathogen - hypothetical protein BMEI0905 1 None None None 17988226 Common dnaA chromosomal replication initiation protein BMEI1943 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 17986929 Common - UREASE ACCESSORY PROTEIN UREE BMEI0646 10 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 17987016 Common - NON-HEME CHLOROPEROXIDASE BMEI0733 88 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 17988128 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, ASNC FAMILY BMEI1845 25 COG1522 Lrp, Transcriptional regulators Transcription 17987424 Common - Hypothetical Membrane Spanning Protein BMEI1141 20 COG5454 COG5454, Predicted secreted protein Function unknown 17987078 Common - glutamate racemase BMEI0795 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 17988320 Common - phosphoenolpyruvate carboxykinase BMEI2037 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 17987542 Common - Hypothetical Membrane Spanning Protein BMEI1259 3 None None None 17988151 Pathogen - hypothetical protein BMEI1868 2 None None None 17986354 Common - aquaporin Z BMEI0070 114 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 17988140 Common - Hypothetical Cytosolic Protein BMEI1857 30 None None None 17987965 Common - hypothetical protein BMEI1682 7 None None None 17987704 Common - TRANSPOSASE BMEI1421 52 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987382 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase BMEI1099 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 17988183 Common - CYTOCHROME O UBIQUINOL OXIDASE SUBUNIT I BMEI1900 167 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 17987981 Common - hypothetical protein BMEI1698 3 None None None 17987054 Common rpsH 30S ribosomal protein S8 BMEI0771 244 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 17987378 Pathogen - hypothetical protein BMEI1095 1 None None None 17987120 Common gltX glutamyl-tRNA synthetase BMEI0837 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 17988246 Common truB tRNA pseudouridine synthase B BMEI1963 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 17986408 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein BMEI0124 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 17987150 Common - NITROGEN REGULATION PROTEIN NTRY BMEI0867 220 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 17988113 Common - 25 KDA OUTER-MEMBRANE IMMUNOGENIC PROTEIN PRECURSOR BMEI1830 30 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 17986751 Common - Hypothetical Cytosolic Protein BMEI0468 9 None None None 17987224 Common - BIS(5'-NUCLEOSYL)-TETRAPHOSPHATASE (ASYMMETRICAL) BMEI0941 31 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 17988109 Pathogen - hypothetical protein BMEI1826 1 None None None 17987006 Pathogen - hypothetical protein BMEI0723 2 None None None 17987134 Common - ENOLASE BMEI0851 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 17987591 Common - HISTIDINOL-PHOSPHATE AMINOTRANSFERASE BMEI1308 164 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 17987173 Common tgt queuine tRNA-ribosyltransferase BMEI0890 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 17987404 Common - Hypothetical Cytosolic Protein BMEI1121 26 COG5467 COG5467, Uncharacterized conserved protein Function unknown 17988042 Common metH B12-dependent methionine synthase BMEI1759 175 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 17987259 Pathogen - hypothetical protein BMEI0976 2 None None None 17987990 Common - MANDELATE RACEMASE BMEI1707 106 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 17987634 Common - PENICILLIN-BINDING PROTEIN 1A BMEI1351 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 17988232 Common - TRANSCRIPTIONAL REGULATOR, MARR FAMILY BMEI1949 20 COG1846 MarR, Transcriptional regulators Transcription 17986577 Common - LSU ribosomal protein L36P BMEI0294 69 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 17988053 Common - METHYLTRANSFERASE BMEI1770 207 COG0313 COG0313, Predicted methyltransferases General function prediction only 17988126 Common - hypothetical protein BMEI1843 3 None None None 17987821 Pathogen - hypothetical protein BMEI1538 1 None None None 17986308 Common - L-SORBOSONE DEHYDROGENASE, NAD(P) DEPENDENT BMEI0024 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 17986995 Common - CBIG PROTEIN / PRECORRIN-3B C17-METHYLTRANSFERASE BMEI0712 117 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 17987431 Common - NADH dehydrogenase subunit K BMEI1148 133 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 17987805 Common - enoyl-CoA hydratase BMEI1522 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 17986593 Common - glyceraldehyde-3-phosphate dehydrogenase BMEI0310 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 17987280 Common - MANNOSYLTRANSFERASE BMEI0997 53 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 17987662 Common - transcriptional regulator BetI BMEI1379 61 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 17988071 Pathogen - hypothetical protein BMEI1788 1 None None None 17987689 Common - TRANSPOSASE BMEI1406 23 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17986360 Common - inorganic pyrophosphatase BMEI0076 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 17986940 Common - METAL CHELATE OUTER MEMBRANE RECEPTOR BMEI0657 128 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 17987697 Common - PEROSAMINE SYNTHETASE BMEI1414 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 17987295 Common - INTEGRASE/RECOMBINASE BMEI1012 42 COG0582 XerC, Integrase DNA replication, recombination, and repair 17987038 Common tuf elongation factor Tu BMEI0755 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 17986926 Common - UREASE ACCESSORY PROTEIN URED BMEI0643 76 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 17986710 Common - hypothetical protein BMEI0427 27 None None None 17987260 Common - putative sugar kinase BMEI0977 221 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 17988241 Common - enoyl-(acyl carrier protein) reductase BMEI1958 231 COG0623 FabI, Enoyl- acyl-carrier-protein 17986398 Common - ASPARAGINE-BINDING PERIPLASMIC PROTEIN PRECURSOR BMEI0114 46 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 17986416 Common - Fe-S OXIDOREDUCTASE BMEI0132 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 17988059 Common hrcA heat-inducible transcription repressor BMEI1776 148 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 17986814 Pathogen - hypothetical protein BMEI0531 1 None None None 17987894 Common - dihydroorotate dehydrogenase 2 BMEI1611 225 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 17988099 Common - Sensory Transduction Protein Kinase BMEI1816 78 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 17986975 Common - hypothetical protein BMEI0692 18 COG5446 COG5446, Predicted integral membrane protein Function unknown 17987874 Common - FERREDOXIN-NADP REDUCTASE BMEI1591 120 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 17986437 Pathogen - hypothetical protein BMEI0153 4 COG4747 COG4747, ACT domain-containing protein General function prediction only 17987911 Pathogen - hypothetical protein BMEI1628 1 None None None 17987838 Common - TRANSPORTER, MFS superfamily BMEI1555 68 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 17987052 Common rplE 50S ribosomal protein L5 BMEI0769 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 17987492 Common - GENERAL L-AMINO ACID TRANSPORT SYSTEM PERMEASE PROTEIN AAPM BMEI1209 181 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 17987722 Common - CHROMOSOME SEGREGATION PROTEIN SMC2 BMEI1439 175 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 17986481 Common - LYSOSTAPHIN BMEI0197 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 17986647 Common - BIOPOLYMER TRANSPORT EXBD PROTEIN BMEI0364 128 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 17987754 Common - 4-AMINO-4-DEOXYCHORISMATE LYASE BMEI1471 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 17987558 Common - hypothetical protein BMEI1275 108 COG2135 COG2135, Uncharacterized conserved protein Function unknown 17986774 Common - PROTEIN SECRETION CHAPERONIN CSAA BMEI0491 121 COG0073 ARC1, EMAP domain General function prediction only 17987797 Pathogen - hypothetical protein BMEI1514 2 None None None 17988102 Common - ALCOHOL DEHYDROGENASE CLASS III BMEI1819 209 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 161511162 Common obgE GTPase ObgE BMEI0206 249 COG0536 Obg, Predicted GTPase General function prediction only 17986441 Common - isopropylmalate isomerase large subunit BMEI0157 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 17986401 Pathogen - hypothetical protein BMEI0117 1 None None None 17986545 Common - HIGH-AFFINITY BRANCHED-CHAIN AMINO ACID TRANSPORT ATP-BINDING PROTEIN BRAG BMEI0261 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 17986915 Common - Hypothetical Membrane Spanning Protein BMEI0632 4 None None None 17987682 Common - TRANSPOSASE BMEI1399 24 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17988265 Common - hypothetical protein BMEI1982 6 None None None 17986898 Common - PHOSPHOSERINE PHOSPHATASE BMEI0615 153 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 17987371 Common - SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE BMEI1088 16 COG5373 COG5373, Predicted membrane protein Function unknown 17988307 Common - Hypothetical Cytosolic Protein BMEI2024 59 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 17987538 Common - glycoprotein/polysaccharide metabolism BMEI1255 48 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 17986660 Common - RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE D BMEI0377 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 17987214 Common - PUTATIVE THIOSULFATE SULFURTRANSFERASE BMEI0931 145 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 17987086 Common - hypothetical protein BMEI0803 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 17987393 Common - SECRETION ACTIVATOR PROTEIN BMEI1110 31 COG3926 zliS, Putative secretion activating protein General function prediction only 17987702 Common - hypothetical protein BMEI1419 3 None None None 17987621 Common - hypothetical protein BMEI1338 4 None None None 17988331 Common hslU ATP-dependent protease ATP-binding subunit BMEI2048 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 17988339 Common - DNA polymerase III subunit epsilon BMEI2056 193 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 17987566 Common - Hypothetical Cytosolic Protein BMEI1283 31 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 17986743 Common - MOXR PROTEIN BMEI0460 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 17986905 Common - KUP SYSTEM POTASSIUM UPTAKE PROTEIN BMEI0622 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 17987252 Common nadE NAD synthetase BMEI0969 235 COG0171 NadE, NAD synthase Coenzyme metabolism 17987688 Common - TRANSPOSASE BMEI1405 40 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17986767 Common - hypothetical protein BMEI0484 10 None None None 17988203 Common - hypothetical protein BMEI1920 13 None None None 17987988 Pathogen - hypothetical protein BMEI1705 1 None None None 17987813 Common glyQ glycyl-tRNA synthetase subunit alpha BMEI1530 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 17986326 Common - SHIKIMATE KINASE BMEI0042 196 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 17986867 Common - CELL DIVISION PROTEIN FTSA BMEI0584 184 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 17987449 Common - O-acetylhomoserine aminocarboxypropyltransferase BMEI1166 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 17987938 Common - UREASE ACCESSORY PROTEIN URED BMEI1655 75 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 17986754 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI0471 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 17987723 Common - THIOL:DISULFIDE INTERCHANGE PROTEIN DSBA BMEI1440 92 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 17986843 Common - TRANSPORTER BMEI0560 111 COG0679 COG0679, Predicted permeases General function prediction only 161511118 Common infB translation initiation factor IF-2 BMEI1965 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 17986807 Common - hypothetical protein BMEI0524 14 COG5395 COG5395, Predicted membrane protein Function unknown 17987862 Common - PERIPLASMIC MANNITOL-BINDING PROTEIN BMEI1579 87 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 17987840 Common - ARSENATE REDUCTASE BMEI1557 110 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 17986447 Pathogen - hypothetical protein BMEI0163 1 None None None 17988255 Common lnt apolipoprotein N-acyltransferase BMEI1972 167 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 17987849 Common - cytochrome c oxidase, diheme subunit, membrane-bound BMEI1566 82 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 17988001 Common - Purine/pyrimidine phosphoribosyl transferase BMEI1718 51 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 17987210 Common - MULTIDRUG RESISTANCE PROTEIN B BMEI0927 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 17988305 Common - THIOREDOXIN C-1 BMEI2022 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 17986287 Common rho transcription termination factor Rho BMEI0003 212 COG1158 Rho, Transcription termination factor Transcription 17987127 Common trpD anthranilate phosphoribosyltransferase BMEI0844 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 17987192 Common hisI phosphoribosyl-AMP cyclohydrolase BMEI0909 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 17986555 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase BMEI0271 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 17987115 Common fabZ (3R)-hydroxymyristoyl-(acyl carrier protein) dehydratase BMEI0832 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 17986760 Common - MONOAMINE OXIDASE REGULATORY PROTEIN, PUTATIVE BMEI0477 59 COG2030 MaoC, Acyl dehydratase Lipid metabolism 17987266 Common - RIBOSOMAL LARGE SUBUNIT PSEUDOURIDINE SYNTHASE C BMEI0983 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 17987833 Common engA GTP-binding protein EngA BMEI1550 234 COG1160 COG1160, Predicted GTPases General function prediction only 17987528 Common - florfenicol resistance protein BMEI1245 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 17988318 Common - SENSOR PROTEIN CHVG BMEI2035 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 17988209 Common - hydroxymethylglutaryl-CoA lyase BMEI1926 97 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 17988284 Common - CHAPERONE PROTEIN DNAJ BMEI2001 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 17987456 Common - Hypothetical Membrane Spanning Protein BMEI1173 7 None None None 17987714 Common - BIOY PROTEIN BMEI1431 95 COG1268 BioY, Uncharacterized conserved protein General function prediction only 17987332 Common - BACTERIOFERRITIN COMIGRATORY PROTEIN BMEI1049 217 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 17987610 Common - GLUTAMATE-AMMONIA-LIGASE ADENYLYLTRANSFERASE BMEI1327 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 17986793 Common - LEUCINE-RESPONSIVE REGULATORY PROTEIN BMEI0510 164 COG1522 Lrp, Transcriptional regulators Transcription 17988277 Common - MG(2+) CHELATASE FAMILY PROTEIN BMEI1994 194 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 17988048 Common - phosphoadenosine phosphosulfate reductase BMEI1765 154 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 17987276 Pathogen - hypothetical protein BMEI0993 1 None None None 17986623 Common - PEPTIDOGLYCAN-ASSOCIATED LIPOPROTEIN BMEI0340 154 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 17987734 Common - PROCESSING PEPTIDASE BMEI1451 201 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 17987512 Common - Hypothetical exonuclease BMEI1229 4 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 17986983 Common - PRECORRIN-3B C17-METHYLTRANSFERASE BMEI0700 8 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 17987314 Pathogen - hypothetical protein BMEI1031 1 None None None 17987922 Common - dihydropyrimidine dehydrogenase BMEI1639 134 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 17987326 Common - NIFS PROTEIN BMEI1043 231 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 17987784 Common - TRANSGLYCOSYLASE ASSOCIATED PROTEIN BMEI1501 14 COG2261 COG2261, Predicted membrane protein Function unknown 17987889 Common - SENSORY TRANSDUCTION HISTIDINE KINASE BMEI1606 228 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 17987242 Common - FERREDOXIN, 2FE-2S BMEI0959 77 COG0633 Fdx, Ferredoxin Energy production and conversion 17986935 Pathogen - hypothetical protein BMEI0652 1 None None None 17987462 Common ihfA integration host factor subunit alpha BMEI1179 196 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 17987272 Common - THYMIDYLATE KINASE BMEI0989 224 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 17987094 Common - L-SERINE DEHYDRATASE 1 BMEI0811 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 17988067 Common - SMALL HEAT SHOCK PROTEIN HSPA BMEI1784 64 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 17987761 Common - acyl-carrier-protein S-malonyltransferase BMEI1478 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 17987202 Common - NITRILOTRIACETATE MONOOXYGENASE COMPONENT B BMEI0919 86 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 17987972 Pathogen - hypothetical protein BMEI1689 1 None None None 17986880 Common - serine/threonine protein kinase BMEI0597 10 COG2112 COG2112, Predicted Ser/Thr protein kinase Signal transduction mechanisms 17987562 Common - Hypothetical Cytosolic Protein BMEI1279 6 None None None 17986781 Common - COLD SHOCK PROTEIN CSPA BMEI0498 176 COG1278 CspC, Cold shock proteins Transcription 17986847 Common - DNAJ-LIKE PROTEIN DJLA BMEI0564 70 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 17987414 Common - Inositol monophosphatase and related sulfite synthesis enzyme BMEI1131 178 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 17987646 Common - Hypothetical Cytosolic Protein BMEI1363 3 None None None 17987957 Common - hypothetical protein BMEI1674 25 None None None 17987099 Common - ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPA BMEI0816 230 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 17987868 Common - Na+ DRIVEN MULTIDRUG EFFLUX PUMP BMEI1585 154 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 17987581 Common - Hypothetical Cytosolic Protein BMEI1298 61 COG1432 COG1432, Uncharacterized conserved protein Function unknown 17987639 Common - peptidoglycan binding domain containing protein BMEI1356 8 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 17987185 Pathogen - RECOMBINASE BMEI0902 1 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 17986561 Common - FERREDOXIN II BMEI0278 157 COG1146 COG1146, Ferredoxin Energy production and conversion 17987871 Common - carboxynorspermidine dehydrogenase BMEI1588 54 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 17987803 Common - RESPONSE REGULATOR PROTEIN BMEI1520 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 17987140 Common - dihydrolipoamide dehydrogenase BMEI0857 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 17987249 Common - MUCONATE CYCLOISOMERASE I BMEI0966 120 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 17986319 Common - D-ALANYL-D-ALANINE CARBOXYPEPTIDASE BMEI0035 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 17987149 Common - NITROGEN ASSIMILATION REGULATORY PROTEIN BMEI0866 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 17987878 Pathogen - hypothetical protein BMEI1595 1 None None None 17987884 Common - hypothetical protein BMEI1601 3 None None None 17987387 Common - ARGININE/ORNITHINE-BINDING PERIPLASMIC PROTEIN PRECURSOR BMEI1104 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 17986508 Pathogen - hypothetical protein BMEI0224 1 None None None 17986954 Common - INTEGRAL MEMBRANE PROTEIN / HEMOLYSIN BMEI0671 216 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 17987913 Common - ACRIFLAVIN RESISTANCE PROTEIN A PRECURSOR BMEI1630 135 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 17986992 Common - 4-HYDROXYPHENYLACETATE 3-MONOOXYGENASE BMEI0709 112 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 17986637 Common - Hypothetical Membrane Spanning Protein BMEI0354 24 COG1633 COG1633, Uncharacterized conserved protein Function unknown 17987337 Common - peptide chain release factor 2 BMEI1054 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 17987000 Common - 22 KDA OUTER MEMBRANE PROTEIN PRECURSOR BMEI0717 20 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 17987699 Common - O-ANTIGEN EXPORT SYSTEM ATP-BINDING PROTEIN RFBB BMEI1416 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 17987747 Common - protoheme IX farnesyltransferase BMEI1464 172 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 17986514 Common - hypothetical protein BMEI0230 53 COG3762 COG3762, Predicted membrane protein Function unknown 17987453 Common - AGMATINASE BMEI1170 130 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 17987850 Common - NITROGEN FIXATION PROTEIN FIXG BMEI1567 77 COG0348 NapH, Polyferredoxin Energy production and conversion 17987608 Common - Sensory Transduction Protein Kinase BMEI1325 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 17987674 Common - RIBOSE TRANSPORT SYSTEM PERMEASE PROTEIN RBSC BMEI1391 136 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 17987694 Common - TRANSPOSASE BMEI1411 24 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987952 Common - hypothetical protein BMEI1669 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 17987206 Common - 3-DEMETHYLUBIQUINONE-9 3-METHYLTRANSFERASE BMEI0923 53 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 17988015 Common - PHOSPHOMETHYLPYRIMIDINE KINASE / HYDROXYMETHYLPYRIMIDINE KINASE BMEI1732 217 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 17988060 Common - GRPE PROTEIN BMEI1777 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 17986947 Common - SUGAR TRANSPORT SYSTEM PERMEASE PROTEIN BMEI0664 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 17987230 Common - Sensory Transduction Protein Kinase BMEI0947 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 17987657 Common - MAGNESIUM AND COBALT TRANSPORT PROTEIN CORA BMEI1374 153 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 17986877 Common - CHLORAMPHENICOL ACETYLTRANSFERASE BMEI0594 73 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 17988167 Common - Dienelactone hydrolase and related enzyme BMEI1884 63 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 161511161 Common - acetyl-CoA synthetase BMEI0238 212 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 17987626 Common - hypothetical protein BMEI1343 31 COG5449 COG5449, Uncharacterized conserved protein Function unknown 17986534 Common - F0F1 ATP synthase subunit gamma BMEI0250 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 17986472 Common - 3-demethylubiquinone-9 3-methyltransferase BMEI0188 142 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 17986570 Common - hypothetical protein BMEI0287 3 None None None 17987023 Common - INOSINE-5'-MONOPHOSPHATE DEHYDROGENASE BMEI0740 153 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 17986973 Common - cobyric acid synthase BMEI0690 154 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 17988090 Common - Hypothetical Cytosolic Protein BMEI1807 26 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 17986884 Common - hypothetical protein BMEI0601 25 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 17986434 Common - TRANSCRIPTIONAL REGULATOR, ARSR FAMILY BMEI0150 40 COG0640 ArsR, Predicted transcriptional regulators Transcription 17988273 Common - Hypothetical Membrane Spanning Protein BMEI1990 80 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 17987461 Common - TRANSCRIPTIONAL REGULATOR, MERR FAMILY BMEI1178 91 COG0789 SoxR, Predicted transcriptional regulators Transcription 17986641 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase BMEI0358 183 COG0756 Dut, dUTPase Nucleotide transport and metabolism 17986675 Common - RIBOSE TRANSPORT SYSTEM PERMEASE PROTEIN RBSC BMEI0392 168 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 17988343 Common - hypothetical protein BMEI2060 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 17987772 Common - ribitol-5-phosphate dehydrogenase [NADP('+)] BMEI1489 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17986527 Common - hypothetical protein BMEI0243 7 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 17986853 Pathogen - hypothetical protein BMEI0570 1 None None None 17986458 Common - GLYCEROL-3-PHOSPHATE DEHYDROGENASE (NAD(P)+) BMEI0174 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 17987548 Common - SURVIVAL PROTEIN SURA PRECURSOR (PEPTIDYL-PROLYL CIS-TRANS ISOMERASE SURA) BMEI1265 62 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 17986704 Common - PLEIOTROPIC REGULATORY PROTEIN BMEI0421 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 17987359 Common - PROTEIN TRANSLOCASE SUBUNIT SECD / PROTEIN TRANSLOCASE SUBUNIT SECF BMEI1076 216 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 17988157 Common - hypothetical protein BMEI1874 25 COG4544 COG4544, Uncharacterized conserved protein Function unknown 17987137 Common - PYRUVATE DEHYDROGENASE E1 COMPONENT, ALPHA SUBUNIT BMEI0854 168 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 17987363 Common pcm protein-L-isoaspartate O-methyltransferase BMEI1080 154 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 17986520 Common - heat shock protein HtpX BMEI0236 190 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 17987422 Common - LIPOPROTEIN RELEASING SYSTEM TRANSMEMBRANE PROTEIN LOLE BMEI1139 193 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 17986962 Common - POTASSIUM/PROTON ANTIPORTER ROSB BMEI0679 207 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 161511115 Common hisE phosphoribosyl-ATP pyrophosphatase BMEI2040 174 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 17986902 Common - EXODEOXYRIBONUCLEASE V ALPHA CHAIN BMEI0619 108 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 17987170 Common - PEPTIDYL-PROLYL CIS-TRANS ISOMERASE BMEI0887 199 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 17987347 Common aat leucyl/phenylalanyl-tRNA--protein transferase BMEI1064 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 17988117 Common - UBIQUINONE/MENAQUINONE BIOSYNTHESIS METHYLTRANSFERASE UBIE BMEI1834 138 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 17986352 Common - EXODEOXYRIBONUCLEASE III BMEI0068 193 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 17987043 Common rplB 50S ribosomal protein L2 BMEI0760 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 17987328 Common - QUATERNARY AMMONIUM COMPOUND-RESISTANCE PROTEIN QACE BMEI1045 146 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 17987198 Common thrS threonyl-tRNA synthetase BMEI0915 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 17987706 Common - TRANSPOSASE BMEI1423 18 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 17986543 Common - HIGH-AFFINITY BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM PERMEASE PROTEIN LIVM BMEI0259 141 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 17988027 Common - GLUCOSE-RESISTANCE AMYLASE REGULATOR BMEI1744 127 COG1609 PurR, Transcriptional regulators Transcription 17986878 Common - CREA PROTEIN BMEI0595 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 17986484 Common - TRANSPOSASE BMEI0200 46 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 17986801 Common - COLD SHOCK PROTEIN CSPA BMEI0518 179 COG1278 CspC, Cold shock proteins Transcription 17986477 Pathogen - hypothetical protein BMEI0193 1 None None None 17987865 Common - TRANSCRIPTIONAL REGULATORY PROTEIN DEGU BMEI1582 215 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 161511130 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase BMEI1459 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 17987908 Common - UDP-GALACTOSE-LIPID CARRIER TRANSFERASE BMEI1625 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 17988078 Common - hypothetical protein BMEI1795 14 None None None 17986726 Common - hypothetical protein BMEI0443 18 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 17986713 Common - NODULATION PROTEIN NOLR BMEI0430 146 COG0640 ArsR, Predicted transcriptional regulators Transcription 17988110 Common - hypothetical protein BMEI1827 170 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 17986611 Common - TETRATRICOPEPTIDE REPEAT FAMILY PROTEIN BMEI0328 101 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 17988083 Common - Hypothetical Cytosolic Protein BMEI1800 73 COG3176 COG3176, Putative hemolysin General function prediction only 17986868 Common - cell division protein FtsZ BMEI0585 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 17987356 Common - tRNA (uracil-5-)-methyltransferase Gid BMEI1073 98 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 17987017 Common - SERINE ACETYLTRANSFERASE BMEI0734 208 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 17987287 Common - hypothetical protein BMEI1004 10 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 17987999 Common - TREHALOSE/MALTOSE BINDING PROTEIN BMEI1716 96 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 17988134 Common - HEME EXPORTER PROTEIN C BMEI1851 126 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 17986674 Common - SUGAR TRANSPORT ATP-BINDING PROTEIN BMEI0391 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 17986920 Common - COBALT TRANSPORT PROTEIN CBIQ BMEI0637 82 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 17987664 Common - CHOLINE DEHYDROGENASE BMEI1381 87 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 17986911 Common - hypothetical protein BMEI0628 13 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 17986918 Common - COBALT TRANSPORT ATP-BINDING PROTEIN CBIO BMEI0635 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 17986334 Common - COBT PROTEIN BMEI0050 41 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 17986321 Common - Hypothetical Transcriptional Regulatory Protein BMEI0037 103 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 17986748 Common - ASPARTYL/ASPARAGINYL BETA-HYDROXYLASE BMEI0465 25 COG3555 COG3555, Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases Posttranslational modification, protein turnover, chaperones 17988147 Common phhB pterin-4-alpha-carbinolamine dehydratase BMEI1864 105 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 17986386 Common - Universal stress protein family BMEI0102 111 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 17986837 Common - TRANS-ACONITATE METHYLTRANSFERASE BMEI0554 79 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 17986682 Common - DIHYDROXYACETONE KINASE BMEI0399 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 17987429 Common - NADH dehydrogenase subunit M BMEI1146 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 17986532 Common - F0F1 ATP synthase subunit delta BMEI0248 168 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 17988112 Common - 25 KDA OUTER-MEMBRANE IMMUNOGENIC PROTEIN PRECURSOR BMEI1829 29 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 17988097 Common - TRANSPOSASE BMEI1814 54 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17986418 Pathogen - hypothetical protein BMEI0134 1 None None None 17987598 Common - SN-GLYCEROL-3-PHOSPHATE TRANSPORT ATP-BINDING PROTEIN UGPC BMEI1315 11 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 17987669 Common - XYLULOSE KINASE BMEI1386 183 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 17986519 Common - 16S rRNA m(5)C 967 METHYLTRANSFERASE BMEI0235 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 17987517 Pathogen - Hypothetical Membrane Associated Protein BMEI1234 1 None None None 17987102 Common - GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE BMEI0819 81 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 17986765 Common - Hypothetical ATP-binding protein BMEI0482 30 COG0433 COG0433, Predicted ATPase General function prediction only 17987417 Common - EXTENSIN-LIKE PROTEIN BMEI1134 36 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 17987897 Common - hypothetical protein BMEI1614 10 None None None 17987019 Common - FERRIPYOCHELIN BINDING PROTEIN BMEI0736 212 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 17987135 Common - METHYLTRANSFERASE BMEI0852 41 None None None 17987576 Common - coproporphyrinogen III oxidase BMEI1293 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 17987526 Common - FORMATE DEHYDROGENASE ALPHA CHAIN BMEI1243 180 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 17986819 Common - PERIPLASMIC IMMUNOGENIC PROTEIN BMEI0536 87 COG2968 COG2968, Uncharacterized conserved protein Function unknown 17986328 Common - CBS domain containing protein BMEI0044 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 17987391 Common - 2-DEHYDRO-3-DEOXYGLUCONOKINASE BMEI1108 120 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 17987818 Common - NA(+)/H(+) ANTIPORTER 1 / PROTEASE IV BMEI1535 204 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 17987490 Common - salicylate hydroxylase BMEI1207 65 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 17987936 Common ureB urease subunit beta BMEI1653 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 17986981 Common - TRANSPORTER BMEI0698 112 COG0730 COG0730, Predicted permeases General function prediction only 17987536 Common - MOLYBDOPTERIN (MPT) CONVERTING FACTOR, SUBUNIT 1 BMEI1253 82 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 17987161 Common uvrA excinuclease ABC subunit A BMEI0878 239 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 17987835 Common - hypothetical protein BMEI1552 11 None None None 17987556 Pathogen - hypothetical protein BMEI1273 1 None None None 161511139 Common - acetyl-CoA carboxylase biotin carboxylase subunit BMEI1063 237 COG0439 AccC, Biotin carboxylase Lipid metabolism 17987289 Common - Hypothetical Cytosolic Protein BMEI1006 10 COG3422 COG3422, Uncharacterized conserved protein Function unknown 17987089 Common - hypothetical protein BMEI0806 10 None None None 17986343 Pathogen - hypothetical protein BMEI0059 1 None None None 17987373 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein BMEI1090 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 17987684 Common - TRANSPOSASE BMEI1401 119 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987168 Pathogen - hypothetical protein BMEI0885 1 None None None 17987438 Common - NADH dehydrogenase subunit D BMEI1155 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 17986596 Common - Hypothetical Cytosolic Protein BMEI0313 32 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 17987122 Common - COME OPERON PROTEIN 3 BMEI0839 64 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 17987361 Common - ATP-DEPENDENT PROTEASE SUBUNIT BMEI1078 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 17988040 Common - aminotransferase BMEI1757 236 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 17987123 Common - LexA repressor BMEI0840 167 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 17987487 Common - EXOPOLYPHOSPHATASE BMEI1204 170 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 17986293 Common - CHROMOSOME PARTITIONING PROTEIN PARA BMEI0009 198 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 17987073 Common - bacterial alkaline phosphatase BMEI0790 86 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 17987402 Common - Hypothetical Cytosolic Protein BMEI1119 55 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 17986290 Common trmE tRNA modification GTPase TrmE BMEI0006 217 COG0486 ThdF, Predicted GTPase General function prediction only 17986651 Common - hypothetical protein BMEI0368 12 None None None 17986917 Common - INTEGRAL MEMBRANE PROTEIN BMEI0634 71 COG3439 COG3439, Uncharacterized conserved protein Function unknown 17988230 Pathogen - Hypothetical Cytosolic Protein BMEI1947 1 None None None 17986949 Common - short chain dehydrogenase BMEI0666 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17988108 Common - DNA polymerase I BMEI1825 217 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 17988005 Common - SARCOSINE OXIDASE BETA SUBUNIT BMEI1722 115 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 17987941 Pathogen - hypothetical protein BMEI1658 1 None None None 17986581 Pathogen - hypothetical protein BMEI0298 1 None None None 17986883 Common - Hypothetical Membrane Spanning Protein BMEI0600 21 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 17986795 Common - THIOREDOXIN REDUCTASE BMEI0512 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 17987109 Common frr ribosome recycling factor BMEI0826 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 17986591 Common - hypothetical protein BMEI0308 3 None None None 17986391 Common - L-ASPARAGINASE BMEI0107 137 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 17987151 Common - NITROGEN ASSIMILATION REGULATORY PROTEIN NTRX BMEI0868 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 17988076 Common - PUTATIVE PROTEASE IV BMEI1793 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 17987004 Common - Hypothetical Cytosolic Protein BMEI0721 18 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 17986730 Common - LEUCINE-RESPONSIVE REGULATORY PROTEIN BMEI0447 159 COG1522 Lrp, Transcriptional regulators Transcription 17986428 Common - hypothetical protein BMEI0144 5 None None None 17986803 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI0520 89 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 17987236 Common - hypothetical protein BMEI0953 6 None None None 17987117 Common - hypothetical protein BMEI0834 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 17987500 Pathogen - ApeA BMEI1217 2 None None None 17988185 Common - Molybdopterin biosynthesis enzyme BMEI1902 39 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 17987872 Common - CARBOXYNORSPERMIDINE DECARBOXYLASE BMEI1589 51 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 17987129 Common tpiA triosephosphate isomerase BMEI0846 219 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 17987824 Common - TRANSPORTER BMEI1541 106 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 17987454 Common argC N-acetyl-gamma-glutamyl-phosphate reductase BMEI1171 209 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 17987063 Common - 30S ribosomal protein S11 BMEI0780 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 17988282 Common - orotidine 5'-phosphate decarboxylase BMEI1999 172 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 17988205 Common - ACETOACETYL-COA SYNTHETASE BMEI1922 190 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 17987554 Pathogen - 2-ISOPROPYLMALATE SYNTHASE BMEI1271 1 None None None 17988171 Common - LACTOYLGLUTATHIONE LYASE BMEI1888 109 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 17986557 Common - GLCG PROTEIN BMEI0273 25 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 17987268 Common - PHNP PROTEIN BMEI0985 80 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 17988121 Common - SULFATE TRANSPORT ATP-BINDING PROTEIN CYSA BMEI1838 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 17987741 Common - homoserine kinase BMEI1458 66 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 17987711 Common - RIBONUCLEASE III BMEI1428 24 None None None 17988243 Common - METHYLTRANSFERASE BMEI1960 19 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 17987514 Common - NADH-UBIQUINONE OXIDOREDUCTASE 18 KD SUBUNIT BMEI1231 37 None None None 161511156 Common - carbamoyl phosphate synthase small subunit BMEI0526 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 17988003 Common - SARCOSINE OXIDASE ALPHA SUBUNIT BMEI1720 184 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 17988325 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase BMEI2042 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 17987312 Common - OUTER MEMBRANE PROTEIN TOLC BMEI1029 150 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 17987049 Common rpsQ 30S ribosomal protein S17 BMEI0766 219 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 17987828 Common - F0F1 ATP synthase subunit C BMEI1545 39 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 17987274 Common - RARE LIPOPROTEIN A BMEI0991 135 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 17987786 Common - exodeoxyribonuclease VII small subunit BMEI1503 122 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 17987949 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase BMEI1666 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 17986449 Common - 2-octaprenyl-6-methoxyphenyl hydroxylase BMEI0165 132 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 17986738 Common - GLUTATHIONE S-TRANSFERASE BMEI0455 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 17987084 Common - PROPIONYL-COA CARBOXYLASE BETA CHAIN BMEI0801 216 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 17988309 Common - 7.5 KDA CHLOROSOME PROTEIN BMEI2026 188 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 17987056 Common rplR 50S ribosomal protein L18 BMEI0773 213 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 17988336 Common - TRANSPORTER BMEI2053 45 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 17986665 Common - DNA-3-METHYLADENINE GLYCOSIDASE BMEI0382 87 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 17987479 Common - enoyl-CoA hydratase BMEI1196 167 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 17986691 Common - hypothetical protein BMEI0408 6 None None None 17987480 Common - delta-aminolevulinic acid dehydratase BMEI1197 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 17987398 Common - lipid A biosynthesis lauroyl acyltransferase BMEI1115 95 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 17987330 Common - tyrosyl-tRNA synthetase BMEI1047 218 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 17988311 Pathogen - hypothetical protein BMEI2028 1 None None None 17986464 Common - Hypothetical Cytosolic Protein BMEI0180 34 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 17987034 Common - hypothetical protein BMEI0751 6 None None None 17987750 Common - hypothetical protein BMEI1467 13 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 17987472 Common - DIAMINOHYDROXYPHOSPHORIBOSYLAMINOPYRIMIDINE DEAMINASE / 5-AMINO-6-(5-PHOSPHORIBOSYLAMINO)URACIL REDUCTASE BMEI1189 227 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 17987736 Common - Diguanylate cyclase/phosphodiesterase domain 2 (EAL) BMEI1453 180 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 17988257 Common - DIACYGLYCEROL KINASE BMEI1974 134 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 17987725 Common - A/G-SPECIFIC ADENINE GLYCOSYLASE BMEI1442 228 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 17987442 Pathogen - hypothetical protein BMEI1159 1 None None None 17988178 Common - OUTER MEMBRANE PROTEIN BMEI1895 128 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 17987810 Common - GLYCOLATE OXIDASE SUBUNIT GLCD BMEI1527 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 17988295 Common - BENZOATE MEMBRANE TRANSPORT PROTEIN BMEI2012 60 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 17987339 Common - N-ACETYLMURAMOYL-L-ALANINE AMIDASE BMEI1056 180 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 17986367 Common - hypothetical protein BMEI0083 28 None None None 161511143 Common ispDF bifunctional 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase/2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase protein BMEI0863 195 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 17986841 Common - TRANSCRIPTIONAL REGULATOR, ARSR FAMILY BMEI0558 147 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 17987842 Common - SALICYLALDEHYDE DEHYDROGENASE BMEI1559 205 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 17987171 Common - PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A BMEI0888 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 17986732 Common - ANTHRANILATE SYNTHASE BMEI0449 238 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 17988214 Pathogen - hypothetical protein BMEI1931 1 None None None 161511116 Common - DNA starvation/stationary phase protection protein Dps BMEI1980 90 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 17987886 Common - Polysaccharide deacetylase BMEI1603 97 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 17987844 Common - OUTER MEMBRANE PROTEIN BMEI1561 69 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 17987920 Common - CoxG protein BMEI1637 40 COG3427 COG3427, Uncharacterized conserved protein Function unknown 17987445 Pathogen - hypothetical protein BMEI1162 1 None None None 17986505 Common - pyridoxamine kinase BMEI0221 58 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 161511126 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase BMEI1592 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 17987777 Common - hypothetical protein BMEI1494 9 COG3895 COG3895, Predicted periplasmic protein General function prediction only 17987477 Common - EXOPOLYSACCHARIDE SYNTHESIS REGULATORY PROTEIN MUCS BMEI1194 22 COG1846 MarR, Transcriptional regulators Transcription 17986798 Pathogen - hypothetical protein BMEI0515 1 None None None 17987020 Common - hypothetical protein BMEI0737 24 COG3672 COG3672, Predicted periplasmic protein Function unknown 17987866 Common - SENSOR PROTEIN DEGS BMEI1583 164 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 17988340 Common coaE dephospho-CoA kinase BMEI2057 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 17986913 Common - PHENAZINE BIOSYNTHESIS PROTEIN PHZF BMEI0630 110 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 17986572 Common - Hypothetical Cytosolic Protein BMEI0289 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 17986932 Common ureA urease subunit gamma BMEI0649 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 17988333 Common - TRANSCRIPTIONAL REGULATOR BMEI2050 12 COG1396 HipB, Predicted transcriptional regulators Transcription 17987530 Common - RIBONUCLEASE PRECURSOR BMEI1247 39 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 17986987 Common - UROPORPHYRIN-III C-METHYLTRANSFERASE BMEI0704 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 17987263 Common - hypothetical protein BMEI0980 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 17986695 Common - PUTRESCINE TRANSPORT ATP-BINDING PROTEIN POTG BMEI0412 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 17986431 Common xerC site-specific tyrosine recombinase XerC BMEI0147 223 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 17987834 Common - Hypothetical Membrane Associated Protein BMEI1551 20 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 17987112 Common - Membrane Metalloprotease BMEI0829 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 17986643 Common - ABC TRANSPORTER ATP-BINDING PROTEIN / ABC TRANSPORTER PERMEASE PROTEIN BMEI0360 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 17988124 Common - SULFATE-BINDING PROTEIN PRECURSOR BMEI1841 90 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 17987279 Pathogen - hypothetical protein BMEI0996 1 None None None 17988250 Common nusA transcription elongation factor NusA BMEI1967 219 COG0195 NusA, Transcription elongation factor Transcription 161511138 Common - seryl-tRNA synthetase BMEI1082 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 17987436 Common - NADH-QUINONE OXIDOREDUCTASE CHAIN F BMEI1153 166 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 17986529 Common - PRIMOSOMAL PROTEIN N' BMEI0245 188 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 17988144 Common - ARYLESTERASE PRECURSOR BMEI1861 107 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 17988046 Common - hypothetical protein BMEI1763 8 None None None 17988289 Common - Hypothetical Cytosolic Protein BMEI2006 16 None None None 161511165 Common - malate dehydrogenase BMEI0137 199 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 17986791 Common greA transcription elongation factor GreA BMEI0508 203 COG0782 GreA, Transcription elongation factor Transcription 17988136 Common - HEME EXPORTER PROTEIN A BMEI1853 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 17987154 Pathogen - hypothetical protein BMEI0871 1 None None None 17987516 Common - L-LACTATE PERMEASE BMEI1233 103 COG1620 LldP, L-lactate permease Energy production and conversion 17987986 Pathogen - hypothetical protein BMEI1703 1 None None None 17987184 Common - RESOLVASE BMEI0901 134 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 17986314 Common - Hypothetical Cytosolic Protein BMEI0030 4 None None None 17987822 Pathogen - hypothetical protein BMEI1539 2 None None None 17987710 Common - CAPD PROTEIN BMEI1427 169 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 17987719 Common - pyruvate phosphate dikinase BMEI1436 234 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 17986736 Common - MUTT/NUDIX FAMILY PROTEIN BMEI0453 49 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 17987748 Common - CYTOCHROME C OXIDASE POLYPEPTIDE I BMEI1465 167 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 17987196 Common - PENICILLIN-BINDING PROTEIN 6 (D-ALANYL-D-ALANINE CARBOXYPEPTIDASE FRACTION C) BMEI0913 152 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 17986828 Common - INTEGRAL MEMBRANE PROTEIN BMEI0545 41 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 17987142 Common - lipoyl synthase BMEI0859 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 17988281 Common - Hypothetical Cytosolic Protein BMEI1998 44 COG5470 COG5470, Uncharacterized conserved protein Function unknown 17987482 Common - arginyl-tRNA-protein transferase BMEI1199 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 17987788 Common - GTP CYCLOHYDROLASE II / 3,4-DIHYDROXY-2-BUTANONE 4-PHOSPHATE SYNTHASE BMEI1505 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 17988006 Common - NADP-SPECIFIC GLUTAMATE DEHYDROGENASE BMEI1723 179 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 161511147 Common pyrH uridylate kinase BMEI0825 224 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 17986960 Common - hypothetical protein BMEI0677 41 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 17987728 Common - CHLORIDE CHANNEL PROTEIN BMEI1445 131 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 17986653 Common - SENSORY TRANSDUCTION HISTIDINE KINASE BMEI0370 85 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 17986479 Common - ATP-DEPENDENT CLP PROTEASE, ATP-BINDING SUBUNIT CLPB BMEI0195 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 17986817 Common - hypothetical protein BMEI0534 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 17986944 Common - MYO-INOSITOL 2-DEHYDROGENASE BMEI0661 172 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 17987071 Pathogen - hypothetical protein BMEI0788 1 None None None 17987799 Pathogen - hypothetical protein BMEI1516 1 None None None 17986861 Common - CELL DIVISION PROTEIN FTSW BMEI0578 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 17986480 Common - PROTEIN ERFK/SRFK BMEI0196 86 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 17987253 Common - DIACYLGLYCEROL KINASE BMEI0970 82 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 161511150 Common rplC 50S ribosomal protein L3 BMEI0757 218 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 17987293 Pathogen - hypothetical protein BMEI1010 1 None None None 17986834 Common - hypothetical protein BMEI0551 3 None None None 17988204 Common - ACETOACETYL-COA SYNTHETASE BMEI1921 184 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 17987876 Common panC pantoate--beta-alanine ligase BMEI1593 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 17986388 Common - GLUCARATE TRANSPORTER BMEI0104 83 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 17987731 Common - C-DI-GMP PHOSPHODIESTERASE A-RELATED PROTEIN BMEI1448 164 COG4943 COG4943, Predicted signal transduction protein containing sensor and EAL domains Signal transduction mechanisms 17986616 Common ruvA Holliday junction DNA helicase motor protein BMEI0333 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 17986396 Common - ASPARAGINE TRANSPORT SYSTEM PERMEASE PROTEIN BMEI0112 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 17987648 Common - PROTEASE II BMEI1365 108 COG1770 PtrB, Protease II Amino acid transport and metabolism 17987177 Common - ALKANAL MONOOXYGENASE ALPHA CHAIN BMEI0894 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 17987488 Common - polyphosphate kinase BMEI1205 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 17986298 Pathogen - hypothetical protein BMEI0014 1 None None None 17987632 Common - Phage Portal Protein BMEI1349 60 COG4695 COG4695, Phage-related protein Function unknown 17987270 Common metG methionyl-tRNA synthetase BMEI0987 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 17987399 Common - RIBULOSE-PHOSPHATE 3-EPIMERASE BMEI1116 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 17988259 Common - MIAB PROTEIN BMEI1976 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 17987553 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase BMEI1270 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 17987377 Common - EXOPOLYSACCHARIDE PRODUCTION NEGATIVE REGULATOR PRECURSOR BMEI1094 77 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 17986291 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA BMEI0007 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 17986550 Common - pyruvate carboxylase BMEI0266 239 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 17987948 Pathogen - hypothetical protein BMEI1665 1 None None None 17987125 Common moaC molybdenum cofactor biosynthesis protein C BMEI0842 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 161511157 Common - 50S ribosomal protein L25/general stress protein Ctc BMEI0481 191 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 17986702 Pathogen - hypothetical protein BMEI0419 1 None None None 17986562 Common - TRANSCRIPTIONAL REGULATOR BMEI0279 83 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 17987534 Common uvrC excinuclease ABC subunit C BMEI1251 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 17987164 Common - TRANSCRIPTIONAL REGULATOR, GNTR FAMILY BMEI0881 144 COG2188 PhnF, Transcriptional regulators Transcription 17987537 Common - MOLYBDOPTERIN (MPT) CONVERTING FACTOR, SUBUNIT 2 BMEI1254 153 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 17986413 Common - HYDROXYACYLGLUTATHIONE HYDROLASE, MITOCHONDRIAL BMEI0129 209 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 17988055 Common - putative deoxyribonucleotide triphosphate pyrophosphatase BMEI1772 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 17986881 Common - hypothetical protein BMEI0598 20 COG4702 COG4702, Uncharacterized conserved protein Function unknown 17987155 Common hfq RNA-binding protein Hfq BMEI0872 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 17988269 Common - PHOSPHATE TRANSPORT ATP-BINDING PROTEIN PSTB BMEI1986 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 17986374 Common - short chain dehydrogenase BMEI0090 232 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 17986427 Common - THREONINE EFFLUX PROTEIN BMEI0143 102 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 17987597 Pathogen - hypothetical protein BMEI1314 1 None None None 17987465 Common - Hypothetical Cytosolic Protein BMEI1182 28 None None None 17987573 Common - Hypothetical Membrane Spanning Protein BMEI1290 41 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 17988296 Common - hypothetical protein BMEI2013 7 None None None 17987817 Common - METHYLTRANSFERASE BMEI1534 27 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 17987105 Common - hypothetical protein BMEI0822 14 COG4875 COG4875, Uncharacterized protein conserved in bacteria with a cystatin-like fold Function unknown 17986541 Common - PROLINE RACEMASE BMEI0257 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 17986776 Common - TRANSCRIPTIONAL REGULATORY PROTEIN OMPR BMEI0493 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 17987898 Common - TRANSCRIPTIONAL REGULATOR, ARAC FAMILY BMEI1615 84 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 17986406 Pathogen - hypothetical protein BMEI0122 1 None None None 17987481 Common - Hypothetical Membrane Spanning Protein BMEI1198 16 COG1714 COG1714, Predicted membrane protein/domain Function unknown 17987571 Common - SIGNAL PEPTIDASE I BMEI1288 205 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 17986345 Pathogen - hypothetical protein BMEI0061 1 None None None 17987595 Common - Hypothetical Membrane Spanning Protein BMEI1312 58 COG1284 COG1284, Uncharacterized conserved protein Function unknown 17988095 Pathogen - hypothetical protein BMEI1812 1 None None None 17987998 Common - MALTOSE TRANSPORT SYSTEM PERMEASE PROTEIN MALF BMEI1715 141 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 17986322 Common - hypothetical protein BMEI0038 49 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 17987344 Common - 3-dehydroquinate dehydratase BMEI1061 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 17986524 Common - FUSARIC ACID RESISTANCE PROTEIN FUSB / FUSARIC ACID RESISTANCE PROTEIN FUSC BMEI0240 18 COG1289 COG1289, Predicted membrane protein Function unknown 17987080 Common - TRANSPORTER BMEI0797 125 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 17987221 Common - Universal stress protein UspA and related nucleotide-binding proteins BMEI0938 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 17986365 Common - METHYLTRANSFERASE BMEI0081 63 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 17987885 Common - GLYCOSYLTRANSFERASE BMEI1602 23 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 17986598 Common - 5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE BMEI0315 175 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 17986923 Common - CBIM PROTEIN BMEI0640 17 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 17987909 Common - N-ACETYLGLUCOSAMINYLTRANSFERASE BMEI1626 132 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 161511135 Common acpS 4'-phosphopantetheinyl transferase BMEI1289 161 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 17986693 Common - TRANSCRIPTIONAL REGULATOR, MERR FAMILY BMEI0410 44 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 17986988 Common - cobyrinic acid a,c-diamide synthase BMEI0705 140 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 17986303 Common - LACI-FAMILY TRANSCRIPTION REGULATOR BMEI0019 128 COG1609 PurR, Transcriptional regulators Transcription 17986455 Common - RIBOSOMAL PROTEIN L11 METHYLTRANSFERASE BMEI0171 84 COG3897 COG3897, Predicted methyltransferase General function prediction only 17987218 Common - threonine dehydratase BMEI0935 203 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 17987309 Common - OUTER MEMBRANE PROTEIN E BMEI1026 3 None None None 17986891 Common thyA thymidylate synthase BMEI0608 144 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 17986839 Common - ALPHA-KETOGLUTARATE PERMEASE BMEI0556 138 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 17988176 Common - PROTEIN YBIS PRECURSOR BMEI1893 71 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 17987625 Common - hypothetical protein BMEI1342 30 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 17986463 Common - hypothetical protein BMEI0179 26 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 17987060 Common secY preprotein translocase subunit SecY BMEI0777 236 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 17986758 Common - CYTOCHROME C1 BMEI0475 71 COG2857 CYT1, Cytochrome c1 Energy production and conversion 17986338 Common - MERCURIC RESISTANCE OPERON REGULATORY PROTEIN BMEI0054 141 COG0789 SoxR, Predicted transcriptional regulators Transcription 17986901 Common ilvH acetolactate synthase 3 regulatory subunit BMEI0618 188 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 17987463 Common - 3-oxoacyl-(acyl carrier protein) synthase III BMEI1180 220 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 17986742 Common - hypothetical protein BMEI0459 68 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 17986671 Common - CHOLINE DEHYDROGENASE BMEI0388 90 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 17987901 Common apaG ApaG BMEI1618 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 17987541 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI1258 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 17987186 Common - hypothetical protein BMEI0903 4 None None None 17986359 Common - 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE BMEI0075 154 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 17987047 Common rplP 50S ribosomal protein L16 BMEI0764 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 17988020 Common - ABC TRANSPORTER SUBSTRATE-BINDING PROTEIN BMEI1737 107 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 17986826 Common - CHOLOYLGLYCINE HYDROLASE BMEI0543 55 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 17987770 Common - COLICIN V PRODUCTION PROTEIN BMEI1487 47 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 17986854 Common mraW S-adenosyl-methyltransferase MraW BMEI0571 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 17987443 Common - hypothetical protein BMEI1160 2 None None None 17987193 Common folE GTP cyclohydrolase I BMEI0910 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 17987928 Common - ACRIFLAVIN RESISTANCE PROTEIN B BMEI1645 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 17988156 Common - CELL SURFACE PROTEIN BMEI1873 29 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 17987963 Common - hypothetical protein BMEI1680 17 None None None 161511141 Common - DNA gyrase subunit A BMEI0884 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 17986618 Common - 4-hydroxybenzoyl-CoA thioesterase family active site BMEI0335 125 COG0824 FcbC, Predicted thioesterase General function prediction only 17987419 Pathogen - Hypothetical Cytosolic Protein BMEI1136 2 None None None 17986381 Common - ELECTRON TRANSFER FLAVOPROTEIN ALPHA-SUBUNIT BMEI0097 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 17987709 Common - PUTATIVE UNDECAPRENYL-PHOSPHATE ALPHA-N-ACETYLGLUCOSAMINYLTRANSFERASE BMEI1426 33 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 17987329 Common anmK anhydro-N-acetylmuramic acid kinase BMEI1046 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 17987351 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B BMEI1068 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 17988222 Common - D-3-PHOSPHOGLYCERATE DEHYDROGENASE BMEI1939 224 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 17987237 Common - 2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE BMEI0954 201 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 17986587 Common - Hypothetical Cytosolic Protein BMEI0304 76 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 17986719 Common - DIPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN DPPC BMEI0436 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 17986784 Common - excinuclease ABC subunit B BMEI0501 227 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 17986761 Common - (R)-specific enoyl-CoA hydratase BMEI0478 65 COG2030 MaoC, Acyl dehydratase Lipid metabolism 17987857 Common - XdhC protein (assists in molybdopterin insertion into xanthine dehydrogenase) BMEI1574 65 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 17986950 Common - FUCOSE OPERON FUCU PROTEIN BMEI0667 44 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 17986346 Pathogen - hypothetical protein BMEI0062 1 None None None 17987335 Common - TRANSPOSASE BMEI1052 23 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987022 Common - INTEGRAL MEMBRANE PROTEIN (Rhomboid family) BMEI0739 55 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 17988044 Common - hypothetical protein BMEI1761 4 None None None 17988160 Common - HEMOLYSIN III BMEI1877 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 17987451 Common rplM 50S ribosomal protein L13 BMEI1168 228 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 17988192 Common - hypothetical protein BMEI1909 134 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 161511136 Common hppA membrane-bound proton-translocating pyrophosphatase BMEI1185 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 17986486 Common rpmA 50S ribosomal protein L27 BMEI0202 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 17988184 Common - CYTOCHROME O UBIQUINOL OXIDASE SUBUNIT II BMEI1901 135 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 17986633 Common - ACETYLTRANSFERASE BMEI0350 22 COG0456 RimI, Acetyltransferases General function prediction only 17987614 Common - CYTOCHROME C-TYPE BIOGENESIS PROTEIN CYCL PRECURSOR BMEI1331 91 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 17987427 Common - biotin--protein ligase BMEI1144 221 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 17986564 Common - Hypothetical Cytosolic Protein BMEI0281 79 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 17987420 Common dnaE DNA polymerase III subunit alpha BMEI1137 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 17986714 Pathogen - hypothetical protein BMEI0431 1 None None None 17987509 Common - TRANSCRIPTIONAL REGULATOR BMEI1226 45 COG4933 COG4933, Uncharacterized conserved protein Function unknown 17987411 Common - BOLA PROTEIN FAMILY BMEI1128 81 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 17987228 Common - 6-AMINOHEXANOATE-DIMER HYDROLASE BMEI0945 74 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 17986432 Common rimM 16S rRNA-processing protein BMEI0148 167 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 17986531 Common - hypothetical protein BMEI0247 6 None None None 17988231 Common - CYTOSOL AMINOPEPTIDASE BMEI1948 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 17987143 Common - Hypothetical Cytosolic Protein BMEI0860 101 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 17987696 Common - GDP-mannose 4,6-dehydratase BMEI1413 226 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 17986785 Common - Hypothetical Membrane Spanning Protein BMEI0502 16 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 17987358 Common - Hypothetical Cytosolic Protein BMEI1075 38 COG3737 COG3737, Uncharacterized conserved protein Function unknown 17987931 Common - Sensory Transduction Protein Kinase BMEI1648 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 17987583 Common smpB SsrA-binding protein BMEI1300 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 17987882 Pathogen - hypothetical protein BMEI1599 2 None None None 17986626 Common - CELL DIVISION PROTEIN FTSH BMEI0343 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 17987690 Common - TRANSPOSASE BMEI1407 72 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987286 Common - QUEUINE TRNA-RIBOSYLTRANSFERASE BMEI1003 205 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 17987096 Pathogen - hypothetical protein BMEI0813 2 None None None 17987381 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, ASNC FAMILY BMEI1098 154 COG1522 Lrp, Transcriptional regulators Transcription 17986496 Common - hypothetical protein BMEI0212 2 None None None 17987766 Common rplI 50S ribosomal protein L9 BMEI1483 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 17987743 Common - SURFEIT LOCUS PROTEIN 1 BMEI1460 67 COG3346 COG3346, Uncharacterized conserved protein Function unknown 17986845 Common - LYSOZYME M1 PRECURSOR BMEI0562 45 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 17987498 Common - Hypothetical Membrane Spanning Protein BMEI1215 16 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 17986507 Common - MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE B BMEI0223 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 17986978 Common cobN cobaltochelatase BMEI0695 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 17987676 Common - MANNOSYLTRANSFERASE C BMEI1393 190 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 17986603 Common - TRANSCRIPTIONAL REGULATOR, GNTR FAMILY BMEI0320 132 COG1802 GntR, Transcriptional regulators Transcription 17987057 Common rpsE 30S ribosomal protein S5 BMEI0774 247 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 17986379 Common - SUCCINOGLYCAN BIOSYNTHESIS REGULATOR BMEI0095 171 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 17987029 Common rplA 50S ribosomal protein L1 BMEI0746 237 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 17987973 Pathogen - hypothetical protein BMEI1690 1 None None None 17986872 Common ligA NAD-dependent DNA ligase LigA BMEI0589 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 17986991 Common - LEUCINE-, ISOLEUCINE-, VALINE-, THREONINE-, AND ALANINE-BINDING PROTEIN PRECURSOR BMEI0708 47 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 17988068 Common - hypothetical protein BMEI1785 13 COG5568 COG5568, Uncharacterized small protein Function unknown 17987388 Common - GLYCEROL-3-PHOSPHATASE 1 BMEI1105 113 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 17986331 Common - Molecular chaperones (DnaJ family) BMEI0047 85 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 17987207 Common - XAA-PRO DIPEPTIDASE BMEI0924 171 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 161511166 Common - intracellular septation protein A BMEI0130 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 17986908 Pathogen - hypothetical protein BMEI0625 1 None None None 17987759 Pathogen - hypothetical protein BMEI1476 1 None None None 17987569 Common era GTP-binding protein Era BMEI1286 231 COG1159 Era, GTPase General function prediction only 17987302 Common moaA molybdenum cofactor biosynthesis protein A BMEI1019 200 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 17988064 Common - CysZ-like protein BMEI1781 28 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 17987138 Common - pyruvate dehydrogenase subunit beta BMEI0855 211 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 17988037 Common - bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein BMEI1754 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 17986610 Common - elongation factor P BMEI0327 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 17986512 Common - LemA PROTEIN BMEI0228 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 17987067 Common - recombination factor protein RarA BMEI0784 239 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 17987653 Common - ATPase BMEI1370 78 COG0433 COG0433, Predicted ATPase General function prediction only 17986574 Common - hypothetical protein BMEI0291 18 COG5480 COG5480, Predicted integral membrane protein Function unknown 17987560 Common - Hypothetical Cytosolic Protein BMEI1277 14 COG5451 COG5451, Predicted secreted protein Function unknown 17986840 Common - hypothetical protein BMEI0557 4 COG5586 COG5586, Uncharacterized conserved protein Function unknown 17987918 Common - ARGININE/ORNITHINE TRANSPORT OPERON PROTEIN AOT BMEI1635 23 COG3608 COG3608, Predicted deacylase General function prediction only 17986656 Pathogen - hypothetical protein BMEI0373 1 None None None 17987320 Common - Glycosyltransferase involved in cell wall biogenesis BMEI1037 27 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 17988082 Common - LIPOPROTEIN SIGNAL PEPTIDASE BMEI1799 202 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 17987656 Common - TRANSCRIPTIONAL REGULATOR, GNTR FAMILY BMEI1373 130 COG2186 FadR, Transcriptional regulators Transcription 17987820 Common - 4-DIPHOSPHOCYTIDYL-2-C-METHYL-D-ERYTHRITOL KINASE BMEI1537 177 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 17988287 Common pheT phenylalanyl-tRNA synthetase subunit beta BMEI2004 235 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 17988313 Pathogen - hypothetical protein BMEI2030 1 None None None 17987484 Common - Hypothetical Cytosolic Protein BMEI1201 6 None None None 17987755 Pathogen - hypothetical protein BMEI1472 1 None None None 17987265 Common - TRANSPORTER, DME FAMILY BMEI0982 152 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 17987324 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI1041 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 17988008 Common - GLYCINE BETAINE-BINDING PROTEIN PRECURSOR BMEI1725 87 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 17987781 Common - 1-deoxy-D-xylulose-5-phosphate synthase BMEI1498 226 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 17987051 Common rplX 50S ribosomal protein L24 BMEI0768 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 17987317 Common - HESB PROTEIN BMEI1034 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 161511163 Common rplU 50S ribosomal protein L21 BMEI0201 214 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 17987046 Common rpsC 30S ribosomal protein S3 BMEI0763 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 17986548 Common - LEUCINE-, ISOLEUCINE-, VALINE-, THREONINE-, AND ALANINE-BINDING PROTEIN PRECURSOR BMEI0264 124 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 161511149 Common rpsB 30S ribosomal protein S2 BMEI0823 228 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 17987114 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase BMEI0831 159 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 17987319 Common ppnK inorganic polyphosphate/ATP-NAD kinase BMEI1036 236 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 17986822 Common - hypothetical protein BMEI0539 2 None None None 17987716 Common - hypothetical protein BMEI1433 31 COG5373 COG5373, Predicted membrane protein Function unknown 17987342 Common - ZINC METALLOPROTEASE BMEI1059 94 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 17986443 Common - SUCCINATE DEHYDROGENASE CYTOCHROME B-556 SUBUNIT BMEI0159 86 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 17987291 Pathogen - hypothetical protein BMEI1008 2 None None None 17987717 Pathogen - hypothetical protein BMEI1434 2 None None None 17988228 Common - enoyl-CoA hydratase BMEI1945 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 17986969 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, LYSR FAMILY BMEI0686 192 COG0583 LysR, Transcriptional regulator Transcription 17987996 Common - MALTOSE/MALTODEXTRIN TRANSPORT ATP-BINDING PROTEIN MALK BMEI1713 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 17987984 Pathogen - hypothetical protein BMEI1701 1 None None None 17987298 Pathogen - hypothetical protein BMEI1015 2 None None None 17988324 Common - imidazole glycerol phosphate synthase subunit HisF BMEI2041 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 17987300 Common - SALICYLATE HYDROXYLASE BMEI1017 105 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 17987190 Pathogen - hypothetical protein BMEI0907 1 None None None 17987768 Common - replicative DNA helicase BMEI1485 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 17987841 Common - ADA REGULATORY PROTEIN / O-6-METHYLGUANINE-DNA-ALKYLTRANSFERASE BMEI1558 178 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 17987447 Common - TRANSPOSASE BMEI1164 70 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17986607 Common - hypothetical protein BMEI0324 122 COG1360 MotB, Flagellar motor protein Cell motility and secretion 17986468 Common - GLUTAREDOXIN BMEI0184 120 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 17988301 Common - tryptophan synthase subunit beta BMEI2018 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 17988074 Common - Hypothetical Periplasmic Protein BMEI1791 33 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 17986806 Common - hypothetical protein BMEI0523 4 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 17988087 Common - PII uridylyl-transferase BMEI1804 125 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 17987831 Common - SPORE-CORTEX-LYTIC ENZYME PREPEPTIDE PRECURSOR BMEI1548 48 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 161511121 Common - 3-deoxy-manno-octulosonate cytidylyltransferase BMEI1904 147 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 161511128 Common - phosphatidylserine decarboxylase BMEI1491 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 17987475 Common - SERINE HYDROXYMETHYLTRANSFERASE BMEI1192 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 17988330 Common - ATP-dependent protease peptidase subunit BMEI2047 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 17988017 Common - hypothetical protein BMEI1734 24 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 17988138 Common - aconitate hydratase BMEI1855 223 COG1048 AcnA, Aconitase A Energy production and conversion 17987014 Common - COLD SHOCK PROTEIN BMEI0731 153 COG1278 CspC, Cold shock proteins Transcription 17987307 Common - 3-HYDROXYISOBUTYRATE DEHYDROGENASE BMEI1024 190 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 17987181 Common - Predicted acyl-CoA transferase/carnitine dehydratase BMEI0898 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 17986864 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase BMEI0581 152 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 17987623 Common - Phage Host Specificity Protein BMEI1340 19 None None None 17986415 Common - SIGNAL RECOGNITION PARTICLE RECEPTOR FTSY BMEI0131 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 17986552 Common - D-BETA-HYDROXYBUTYRATE DEHYDROGENASE BMEI0268 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17987721 Common - COBALT-ZINC-CADMIUM RESISTANCE PROTEIN CZCD BMEI1438 185 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 17987525 Common - Hypothetical Membrane Spanning Protein BMEI1242 12 None None None 17986482 Pathogen - hypothetical protein BMEI0198 1 None None None 17986930 Common ureC urease subunit alpha BMEI0647 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 17987968 Pathogen - hypothetical protein BMEI1685 1 None None None 17988338 Common - preprotein translocase subunit SecB BMEI2055 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 17987700 Common - PEROSAMINE SYNTHETASE WBKB BMEI1417 4 None None None 17987053 Common rpsN 30S ribosomal protein S14 BMEI0770 205 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 17987174 Common - TRANSCRIPTIONAL REGULATOR, TETR FAMILY BMEI0891 45 COG1309 AcrR, Transcriptional regulator Transcription 17987846 Common - FERRIC UPTAKE REGULATION PROTEIN BMEI1563 136 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 17988252 Common trmB tRNA (guanine-N(7))-methyltransferase BMEI1969 165 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 17987284 Common - TRANSPOSASE BMEI1001 55 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987892 Common - hypothetical protein BMEI1609 10 None None None 161511159 Common - 7-alpha-hydroxysteroid dehydrogenase BMEI0406 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17987891 Common - PROLINE IMINOPEPTIDASE BMEI1608 96 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 17987685 Common - TRANSPOSASE BMEI1402 58 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987277 Common - hypothetical protein BMEI0994 2 None None None 17987779 Common - TRNA (URACIL-5-) -METHYLTRANSFERASE BMEI1496 197 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 17988106 Common gyrB DNA gyrase subunit B BMEI1823 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 17987175 Common - MEMBRANE FUSION PROTEIN MTRC BMEI0892 166 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 17986473 Common - aspartate kinase BMEI0189 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 17987532 Common - 25 KDA OUTER-MEMBRANE IMMUNOGENIC PROTEIN PRECURSOR BMEI1249 16 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 17988213 Common - LEUCINE-, ISOLEUCINE-, VALINE-, THREONINE-, AND ALANINE-BINDING PROTEIN PRECURSOR BMEI1930 151 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 17986372 Common - hypothetical protein BMEI0088 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 17987497 Common - hypothetical protein BMEI1214 3 None None None 17988267 Common - PHOSPHATE REGULON TRANSCRIPTIONAL REGULATORY PROTEIN PHOB BMEI1984 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 17988029 Common - ALCOHOL DEHYDROGENASE BMEI1746 205 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 17987466 Common - hypothetical protein BMEI1183 22 COG5452 COG5452, Uncharacterized conserved protein Function unknown 17988322 Common - pantothenate kinase BMEI2039 77 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 17987088 Common - hypothetical protein BMEI0805 5 COG4575 ElaB, Uncharacterized conserved protein Function unknown 17987641 Common - Hypothetical Cytosolic Protein BMEI1358 4 None None None 17986664 Common - glutamyl-Q tRNA(Asp) synthetase BMEI0381 245 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 17988142 Common - INTEGRAL MEMBRANE PROTEIN BMEI1859 142 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 17987809 Common - Hypothetical Cytosolic Protein BMEI1526 3 COG3668 ParE, Plasmid stabilization system protein General function prediction only 17987790 Common - hypothetical protein BMEI1507 6 None None None 17988329 Pathogen - hypothetical protein BMEI2046 1 None None None 17987103 Common - TRANSLATION INITIATION INHIBITOR BMEI0820 92 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 17986859 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase BMEI0576 217 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 17988034 Common - TWO COMPONENT RESPONSE REGULATOR BMEI1751 161 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 17987310 Common valS valyl-tRNA synthetase BMEI1027 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 17988244 Common - polynucleotide phosphorylase/polyadenylase BMEI1961 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 17986559 Common - ATP-DEPENDENT DNA HELICASE BMEI0275 65 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 17986404 Pathogen - hypothetical protein BMEI0120 1 None None None 17987333 Common - hypothetical protein BMEI1050 48 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 17986770 Common - ATP synthase beta subunit/transription termination factor rho BMEI0487 94 COG1565 COG1565, Uncharacterized conserved protein Function unknown 17986589 Pathogen - hypothetical protein BMEI0306 2 None None None 17988196 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, LYSR FAMILY BMEI1913 190 COG0583 LysR, Transcriptional regulator Transcription 17986350 Common - TWO COMPONENT RESPONSE REGULATOR BMEI0066 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 17987775 Common - HEAVY METAL TOLERANCE PROTEIN PRECURSOR BMEI1492 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 17987800 Common - pyridoxamine 5'-phosphate oxidase BMEI1517 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 17988191 Common - DNA polymerase III subunits gamma and tau BMEI1908 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 17986810 Common - Hypothetical Cytosolic Protein BMEI0527 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 17987578 Common pyrE orotate phosphoribosyltransferase BMEI1295 107 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 17987812 Common glyS glycyl-tRNA synthetase subunit beta BMEI1529 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 17986296 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI0012 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 17986594 Common - transketolase BMEI0311 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 17987518 Common - SHORT-CHAIN DEHYDROGENASE BMEI1235 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17986815 Common - RNA polymerase sigma factor RpoD BMEI0532 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 17986438 Common - Hypothetical Membrane Spanning Protein BMEI0154 25 None None None 17987603 Common - ELECTRON TRANSFER FLAVOPROTEIN-UBIQUINONE OXIDOREDUCTASE PRECURSOR BMEI1320 108 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 17988342 Common maf Maf-like protein BMEI2059 188 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 17986863 Common murC UDP-N-acetylmuramate--L-alanine ligase BMEI0580 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 17988236 Common - ASPARTYL-TRNA SYNTHETASE BMEI1953 40 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 17987511 Common - ADENYLATE KINASE BMEI1228 14 COG2019 AdkA, Archaeal adenylate kinase Nucleotide transport and metabolism 17986888 Common - BICYCLOMYCIN RESISTANCE PROTEIN BMEI0605 212 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 17987946 Common - ANTIREPRESSOR PROTEIN ANT BMEI1663 40 COG3617 COG3617, Prophage antirepressor Transcription 17986778 Pathogen - hypothetical protein BMEI0495 1 None None None 17987992 Common - OXIDOREDUCTASE UCPA BMEI1709 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17987215 Common - ALANYL-TRNA SYNTHETASE BMEI0932 213 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 17987458 Common - PUTATIVE CAPSULE POLYSACCHARIDE EXPORT PROTEIN PRECURSOR BMEI1175 112 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 17988186 Common - CYTOCHROME C-552 BMEI1903 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 17987753 Common - hypothetical protein BMEI1470 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 17987008 Common - homoserine dehydrogenase BMEI0725 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 17988181 Common - CYTOCHROME O UBIQUINOL OXIDASE OPERON PROTEIN CYOD BMEI1898 56 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 17987400 Common - adenylosuccinate lyase BMEI1117 238 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 17987397 Common - ALCOHOL DEHYDROGENASE BMEI1114 211 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 17987409 Common - Hypothetical Cytosolic Protein BMEI1126 6 None None None 17987966 Common - ZINC-DEPENDENT METALLOPEPTIDASE BMEI1683 8 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 17986658 Common - FERRIC UPTAKE REGULATION PROTEIN BMEI0375 189 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 17988154 Common - hypothetical protein BMEI1871 4 None None None 17987667 Common - TRANSCRIPTIONAL REGULATOR, ARAC FAMILY BMEI1384 46 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 161511153 Common tuf elongation factor Tu BMEI0742 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 17987212 Common - Diguanylate cyclase/phosphodiesterase domain 1 (GGDEF) BMEI0929 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 17987239 Common - DIHYDROPTEROATE SYNTHASE BMEI0956 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 17986739 Common - ACETYLTRANSFERASE BMEI0456 95 COG3153 COG3153, Predicted acetyltransferase General function prediction only 17987191 Common - SERINE PROTEASE BMEI0908 124 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 17986289 Common - THYMIDYLATE KINASE BMEI0005 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 17987521 Common - hypothetical protein BMEI1238 75 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 17986724 Common - GLYCINE BETAINE/L-PROLINE-BINDING PROTEIN PROX BMEI0441 61 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 17986688 Common - 7-ALPHA-HYDROXYSTEROID DEHYDROGENASE BMEI0405 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17986755 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI0472 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 17987353 Common - hypothetical protein BMEI1070 17 COG4929 COG4929, Uncharacterized membrane-anchored protein Function unknown 17988260 Common - 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE BMEI1977 106 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 17986465 Common - MACROLIDE-EFFLUX PROTEIN BMEI0181 125 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 17988290 Common rplT 50S ribosomal protein L20 BMEI2007 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 17986601 Common - 2Fe-2S ferredoxins, iron-sulfur binding protein BMEI0318 14 COG3543 COG3543, Uncharacterized conserved protein Function unknown 17987926 Common - allantoate amidohydrolase BMEI1643 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 17986717 Common - PERIPLASMIC DIPEPTIDE TRANSPORT PROTEIN PRECURSOR BMEI0434 109 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 17986585 Common - QUINONE OXIDOREDUCTASE BMEI0302 188 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 17986383 Common - 3-hydroxybutyryl-CoA dehydrogenase BMEI0099 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 17987961 Pathogen - hypothetical protein BMEI1678 1 None None None 17988219 Common - OLIGOPEPTIDE TRANSPORT SYSTEM PERMEASE PROTEIN OPPB BMEI1936 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 17988019 Common thiE thiamine-phosphate pyrophosphorylase BMEI1736 200 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 17988032 Common glpD glycerol-3-phosphate dehydrogenase BMEI1749 150 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 17986363 Common - cyclohexadienyl dehydrogenase BMEI0079 172 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 17987082 Common - methylmalonyl-CoA mutase BMEI0799 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 17987859 Common - XANTHINE DEHYDROGENASE BMEI1576 122 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 17987593 Common - Hypothetical Membrane Spanning Protein BMEI1310 15 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 17986305 Common - ACETYL-COA:ACETOACETYL-COA TRANSFERASE ALPHA SUBUNIT BMEI0021 93 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 17986324 Common xerD site-specific tyrosine recombinase XerD BMEI0040 222 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 17986453 Common - TRANSCRIPTIONAL REGULATOR, GNTR FAMILY / AMINOTRANSFERASE CLASS-I BMEI0169 221 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 17987546 Common - putative permeases BMEI1263 57 COG0795 COG0795, Predicted permeases General function prediction only 17986566 Common - THIAMINE TRANSPORT ATP-BINDING PROTEIN THIQ BMEI0283 249 COG3840 ThiQ, ABC-type thiamine transport system, ATPase component Coenzyme metabolism 17988275 Common - RARE LIPOPROTEIN A BMEI1992 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 17987132 Common - CTP synthetase BMEI0849 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 17987364 Common surE stationary phase survival protein SurE BMEI1081 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 17988115 Common - FIXR PROTEIN BMEI1832 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17986628 Common - HEAT RESISTANT AGGLUTININ 1 PRECURSOR BMEI0345 25 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 17987860 Common - CHITOOLIGOSACCHARIDE DEACETYLASE BMEI1577 65 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 17988022 Common - ABC TRANSPORTER INTEGRAL MEMBRANE PROTEIN BMEI1739 99 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 17987807 Pathogen - hypothetical protein BMEI1524 1 None None None 17987836 Common - transport protein BMEI1553 58 COG1133 SbmA, ABC-type long-chain fatty acid transport system, fused permease and ATPase components Lipid metabolism 17987059 Common rplO 50S ribosomal protein L15 BMEI0776 211 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 17987551 Common - LYSOSTAPHIN BMEI1268 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 17986729 Common - TRANSCRIPTIONAL REGULATOR, MARR FAMILY BMEI0446 8 None None None 17988299 Common - hypothetical protein BMEI2016 11 COG1434 COG1434, Uncharacterized conserved protein Function unknown 17986924 Common - hypothetical protein BMEI0641 17 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 17987413 Common - BICYCLOMYCIN RESISTANCE PROTEIN BMEI1130 221 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 17986744 Common - hypothetical protein BMEI0461 44 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 17986708 Common - hypothetical protein BMEI0425 22 COG5400 COG5400, Uncharacterized protein conserved in bacteria Function unknown 17987567 Common - Hypothetical protein-tyrosine phosphatase BMEI1284 15 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 17986357 Common - CELL DIVISION PROTEIN FTSX BMEI0073 34 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 17987814 Common - TETRATRICOPEPTIDE REPEAT FAMILY PROTEIN BMEI1531 169 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 17986712 Common - 23S ribosomal RNA methyltransferase BMEI0429 204 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 17987244 Common - Kinesin-like protein BMEI0961 125 COG1511 COG1511, Predicted membrane protein Function unknown 17986348 Pathogen - hypothetical protein BMEI0064 1 None None None 17987955 Common maf Maf-like protein BMEI1672 194 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 17987098 Common clpS ATP-dependent Clp protease adaptor protein ClpS BMEI0815 119 COG2127 COG2127, Uncharacterized conserved protein Function unknown 17987672 Common - IOLE PROTEIN BMEI1389 58 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 17986300 Pathogen - hypothetical protein BMEI0016 1 None None None 17988207 Common - METHYLCROTONYL-COA CARBOXYLASE BMEI1924 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 17988303 Common - acetyl-CoA carboxylase subunit beta BMEI2020 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 17987619 Common - SENSOR PROTEIN PHOQ BMEI1336 206 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 17987383 Common cobS cobalamin synthase BMEI1100 88 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 17987764 Common rpsR 30S ribosomal protein S18 BMEI1481 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 17987975 Common - FLAGELLAR PROTEIN FLGJ BMEI1692 66 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 17986977 Common - COBW PROTEIN BMEI0694 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 17988165 Common - fumarylpyruvate hydrolase BMEI1882 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 17987651 Common - 2-HALOALKANOIC ACID DEHALOGENASE I BMEI1368 40 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 17988062 Common - FRUCTOKINASE BMEI1779 203 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 17987209 Common - MULTIDRUG RESISTANCE PROTEIN A BMEI0926 92 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 17987757 Pathogen - hypothetical protein BMEI1474 1 None None None 17987322 Common - CYSTEINE DESULFHYDRASE / SELENOCYSTEINE LYASE BMEI1039 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 17986938 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI0655 120 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 17987679 Common - PHOSPHOMANNOMUTASE BMEI1396 233 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 17988080 Common - METHYLTRANSFERASE BMEI1797 98 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 17988194 Common - MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE B BMEI1911 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 17987139 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 BMEI0856 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 17987145 Common - PUTATIVE COMPETENCE-DAMAGE PROTEIN BMEI0862 192 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 17987678 Common - MANNOSE-1-PHOSPHATE GUANYLYLTRANSFERASE BMEI1395 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 17986985 Common - cobalt-precorrin-6x reductase BMEI0702 60 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 17987069 Common - OUTER MEMBRANE PROTEIN BMEI0786 168 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 17986492 Common proA gamma-glutamyl phosphate reductase BMEI0208 189 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 17988010 Common - GLYCINE BETAINE/L-PROLINE TRANSPORT ATP-BINDING PROTEIN PROV BMEI1727 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 17986887 Common - TRANSCRIPTIONAL REGULATOR, TETR FAMILY BMEI0604 88 COG1309 AcrR, Transcriptional regulator Transcription 17987232 Common - DNAK SUPPRESSOR PROTEIN HOMOLOG BMEI0949 160 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 17987062 Common rpsM 30S ribosomal protein S13 BMEI0779 240 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 17986998 Common - COBG PROTEIN BMEI0715 64 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 17987587 Common - OUTER MEMBRANE PORIN F PRECURSOR BMEI1304 11 None None None 17986510 Common - chorismate mutase BMEI0226 31 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 17987612 Common - TWO COMPONENT RESPONSE REGULATOR BMEI1329 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 17988131 Common - dihydroxy-acid dehydratase BMEI1848 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 17986424 Common kgd alpha-ketoglutarate decarboxylase BMEI0140 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 17987698 Common - O-ANTIGEN EXPORT SYSTEM PERMEASE PROTEIN RFBD BMEI1415 120 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 17987853 Common - PUTATIVE HYDROXYPYRUVATE REDUCTASE BMEI1570 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 17986942 Common - METAL CHELATE TRANSPORT SYSTEM PERMEASE PROTEIN BMEI0659 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 17986824 Pathogen - hypothetical protein BMEI0541 1 None None None 17987027 Common nusG transcription antitermination protein NusG BMEI0744 215 COG0250 NusG, Transcription antiterminator Transcription 17986646 Common - TONB PROTEIN BMEI0363 7 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 17986952 Pathogen - hypothetical protein BMEI0669 1 None None None 17987880 Common - murein hydrolase exporter BMEI1597 63 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 17986893 Common - HFLK PROTEIN BMEI0610 178 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 17986538 Common - TRANSCRIPTIONAL REGULATOR, GNTR FAMILY BMEI0254 123 COG1802 GntR, Transcriptional regulators Transcription 17987425 Common - LACTOYLGLUTATHIONE LYASE BMEI1142 92 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 17986497 Common - Membrane proteins related to metalloendopeptidase BMEI0213 110 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 17986856 Common - PENICILLIN-BINDING PROTEIN 2 BMEI0573 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 17987349 Common - NADH dehydrogenase BMEI1066 38 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 17986997 Common cobH precorrin-8X methylmutase BMEI0714 119 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 17987585 Common - SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE BMEI1302 154 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 17986631 Pathogen - hypothetical protein BMEI0348 1 None None None 17988238 Common - FERRIC UPTAKE REGULATION PROTEIN BMEI1955 139 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 17986780 Common - Hypothetical Membrane Spanning Protein BMEI0497 8 None None None 17987507 Common - hypothetical protein BMEI1224 8 None None None 17987602 Common - Hypothetical Membrane Spanning Protein BMEI1319 25 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 17988103 Common - ACETYLTRANSFERASE BMEI1820 59 COG2153 ElaA, Predicted acyltransferase General function prediction only 17986794 Common - TRK SYSTEM POTASSIUM UPTAKE PROTEIN TRKH BMEI0511 162 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 17987281 Common - GLYCOSYLTRANSFERASE BMEI0998 6 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 17988079 Common - METHYLTRANSFERASE BMEI1796 23 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 17986392 Common - ASPARAGINE TRANSPORT ATP-BINDING PROTEIN BMEI0108 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 17988098 Common - TRANSPOSASE BMEI1815 72 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17986592 Common pgk phosphoglycerate kinase BMEI0309 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 17987930 Pathogen - hypothetical protein BMEI1647 1 None None None 17986584 Common - hypothetical protein BMEI0301 4 COG5509 COG5509, Uncharacterized small protein containing a coiled-coil domain Function unknown 17986731 Pathogen - hypothetical protein BMEI0448 1 None None None 17987550 Common ksgA dimethyladenosine transferase BMEI1267 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 17986914 Common - hypothetical protein BMEI0631 8 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 17986802 Pathogen - PHOSPHOHYDROLASE (MUTT/NUDIX FAMILY PROTEIN) BMEI0519 3 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 17986948 Common - SUGAR TRANSPORT ATP-BINDING PROTEIN BMEI0665 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 17987635 Common - hypothetical protein BMEI1352 18 COG5402 COG5402, Uncharacterized conserved protein Function unknown 17988247 Common rbfA ribosome-binding factor A BMEI1964 73 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 17988182 Common - CYTOCHROME O UBIQUINOL OXIDASE SUBUNIT III BMEI1899 158 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 17986752 Common - PURINE NUCLEOSIDE PERMEASE BMEI0469 11 COG5042 NUP, Purine nucleoside permease Nucleotide transport and metabolism 17987055 Common rplF 50S ribosomal protein L6 BMEI0772 243 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 17986813 Common dnaG DNA primase BMEI0530 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 17986829 Common - PYRAZINAMIDASE / NICOTINAMIDASE BMEI0546 119 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 17987121 Common - COME OPERON PROTEIN 3 BMEI0838 8 None None None 17986409 Common - ACETYLTRANSFERASE BMEI0125 26 COG0456 RimI, Acetyltransferases General function prediction only 17987416 Common rpsD 30S ribosomal protein S4 BMEI1133 224 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 17986294 Common - CHROMOSOME PARTITIONING PROTEIN PARB BMEI0010 181 COG1475 Spo0J, Predicted transcriptional regulators Transcription 17988100 Common - ATP-DEPENDENT HELICASE HRPB BMEI1817 84 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 17986489 Common - IMMUNOGLOBULIN-BINDING PROTEIN EIBE BMEI0205 6 None None None 17986436 Common - Hypothetical Cytosolic Protein BMEI0152 38 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 17987172 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase BMEI0889 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 17986579 Common - PHOSPHORIBOSYLAMINOIMIDAZOLE CARBOXYLASE CATALYTIC SUBUNIT BMEI0296 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 17986576 Common - 2-HYDROXY-6-OXO-2,4-HEPTADIENOATE HYDROLASE BMEI0293 52 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 17987577 Common - NITROGEN FIXATION REGULATION PROTEIN FIXK BMEI1294 143 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 17988043 Common - hypothetical protein BMEI1760 6 None None None 17986546 Common - hypothetical protein BMEI0262 10 None None None 17987076 Common - PROTEASE I BMEI0793 144 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 17987912 Common - MULTIDRUG RESISTANCE PROTEIN MEXB BMEI1629 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 17987806 Common - hypothetical protein BMEI1523 10 None None None 17987370 Common - BETA-HEXOSAMINIDASE A BMEI1087 169 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 17987407 Common - phosphoribosylformylglycinamidine synthase subunit I BMEI1124 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 17986440 Common rplS 50S ribosomal protein L19 BMEI0156 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 17988291 Common rpmI 50S ribosomal protein L35 BMEI2008 37 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 17988315 Common - PTS SYSTEM, IIA COMPONENT BMEI2032 95 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 17987160 Common - DNA-BINDING PROTEIN HU-ALPHA BMEI0877 213 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 17986890 Common - Hypothetical Cytosolic Protein BMEI0607 16 None None None 17987919 Common pgi glucose-6-phosphate isomerase BMEI1636 199 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 17986941 Common - METAL CHELATE PERIPLASMIC BINDING PROTEIN BMEI0658 43 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 17987533 Common - short chain dehydrogenase BMEI1250 231 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17987794 Common - Phosphoglycerate mutase/fructose-2,6-bisphosphatase BMEI1511 139 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 17988233 Common - GAMMA-D-GLUTAMYL-L-DIAMINO ACID ENDOPEPTIDASE II BMEI1950 69 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 17988033 Common - GLYCEROL-3-PHOSPHATE REGULON REPRESSOR BMEI1750 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 17987159 Common - ATP-DEPENDENT PROTEASE LA BMEI0876 214 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 17987037 Common - elongation factor G BMEI0754 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 17986967 Common - SARCOSINE DEHYDROGENASE BMEI0684 172 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 17987848 Common - cytochrome c oxidase, monoheme subunit, membrane-bound BMEI1565 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 17987993 Common - OXIDOREDUCTASE BMEI1710 67 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 17986417 Common dapF diaminopimelate epimerase BMEI0133 184 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 17986683 Common - hypothetical protein BMEI0400 3 None None None 17987213 Common - ACETYLTRANSFERASE BMEI0930 31 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 17987493 Common - GENERAL L-AMINO ACID TRANSPORT SYSTEM PERMEASE PROTEIN AAPQ BMEI1210 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 17986397 Common - ASPARAGINE TRANSPORT SYSTEM PERMEASE PROTEIN BMEI0113 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 17987681 Common - TRANSPOSASE BMEI1398 58 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17986445 Common sdhA succinate dehydrogenase flavoprotein subunit BMEI0161 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 17987937 Common - UREASE GAMMA SUBUNIT BMEI1654 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 17987680 Common - TRANSPOSASE BMEI1397 44 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 17986772 Common - hypothetical protein BMEI0489 30 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 17987421 Common - LIPOPROTEIN RELEASING SYSTEM ATP-BINDING PROTEIN LOLD BMEI1138 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 17987944 Common - RECOMBINASE BMEI1661 88 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 17986773 Common - Hypothetical Cytosolic Protein BMEI0490 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 17987839 Common - INTEGRAL MEMBRANE PROTEIN BMEI1556 18 COG4129 COG4129, Predicted membrane protein Function unknown 17987559 Common - PHOSPHOHYDROLASE (MUTT/NUDIX FAMILY PROTEIN) BMEI1276 57 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 17987687 Common - MANNOSYLTRANSFERASE BMEI1404 200 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 17986639 Common - Type 1 capsular polysaccharide biosynthesis protein J BMEI0356 8 None None None 17987473 Common - hypothetical protein BMEI1190 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 17986749 Common - ACETYLTRANSFERASE BMEI0466 89 COG3153 COG3153, Predicted acetyltransferase General function prediction only 17988056 Common - LACTOYLGLUTATHIONE LYASE, PUTATIVE BMEI1773 20 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 17986768 Common - XAA-PRO DIPEPTIDASE BMEI0485 55 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 17987251 Common gltX glutamyl-tRNA synthetase BMEI0968 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 17986361 Common - CATION TRANSPORT PROTEIN CHAC BMEI0077 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 17986808 Common - ZINC PROTEASE BMEI0525 87 COG2321 COG2321, Predicted metalloprotease General function prediction only 17986876 Common - SCO2 PROTEIN BMEI0593 102 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 17987513 Common - Hypothetical Cytosolic Protein BMEI1230 3 None None None 17986844 Common - MEMBRANE-BOUND LYTIC MUREIN TRANSGLYCOSYLASE B BMEI0561 100 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 17987863 Common - MANNITOL TRANSPORTER, LARGE SUBUNIT BMEI1580 122 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 17987441 Common - NADH dehydrogenase subunit A BMEI1158 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 17987724 Common - Hypothetical Cytosolic Protein BMEI1441 17 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 161511142 Common clpP ATP-dependent Clp protease proteolytic subunit BMEI0874 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 161511119 Common rpsO 30S ribosomal protein S15 BMEI1962 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 17986435 Common - hypothetical protein BMEI0151 17 None None None 17986866 Common - CELL DIVISION PROTEIN FTSQ BMEI0583 76 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 17986759 Common - adenine phosphoribosyltransferase BMEI0476 186 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 17987843 Common - SALICYLALDEHYDE DEHYDROGENASE BMEI1560 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 17987261 Common - NITROGEN REGULATORY PROTEIN P-II BMEI0978 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 17988072 Common - RNA polymerase factor sigma-54 BMEI1789 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 17987061 Common adk adenylate kinase BMEI0778 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 17987128 Common - PEPTIDYL-PROLYL CIS-TRANS ISOMERASE D BMEI0845 130 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 17987085 Common - TRANSCRIPTIONAL REGULATOR, MERR FAMILY BMEI0802 50 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 17986692 Common - isocitrate lyase BMEI0409 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 17987392 Common - ALDOSE 1-EPIMERASE BMEI1109 93 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 17986567 Common thiP thiamin transporter membrane protein BMEI0284 89 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 17987348 Common - RETROVIRUS-RELATED POL POLYPROTEIN BMEI1065 28 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 17987258 Common - phosphoglycolate phosphatase BMEI0975 175 COG0546 Gph, Predicted phosphatases General function prediction only 17987980 Common - virulence-associated protein E BMEI1697 29 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 17988332 Common - hypothetical protein BMEI2049 6 None None None 17986849 Common - SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE BMEI0566 114 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 17987315 Pathogen - Heavy Metal Binding Protein BMEI1032 3 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 17986624 Common - TPR repeat containing exported protein BMEI0341 97 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 17988285 Common dnaK molecular chaperone DnaK BMEI2002 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 17988093 Common - hypothetical protein BMEI1810 30 COG5321 COG5321, Uncharacterized protein conserved in bacteria Function unknown 17987827 Common - F0F1 ATP synthase subunit B' BMEI1544 36 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 161511122 Common - tryptophanyl-tRNA synthetase BMEI1806 232 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 17986788 Common - Hypothetical Membrane Associated Protein BMEI0505 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 17987744 Common - ZINC-FINGER PROTEIN BMEI1461 25 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 17986737 Common - OUTER MEMBRANE PROTEIN W PRECURSOR BMEI0454 72 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 17987457 Common - ATPase, ParA FAMILY BMEI1174 14 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 17986976 Common cobU adenosylcobinamide kinase/adenosylcobinamide-phosphate guanylyltransferase BMEI0693 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 17987792 Pathogen - hypothetical protein BMEI1509 1 None None None 17986288 Common - Hypothetical Cytosolic Protein BMEI0004 3 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 17987116 Common - UDP-N-acetylglucosamine acyltransferase BMEI0833 147 COG1043 LpxA, Acyl- acyl carrier protein 17987296 Common - Hypothetical Membrane Spanning Protein BMEI1013 16 COG2261 COG2261, Predicted membrane protein Function unknown 17987982 Pathogen - hypothetical protein BMEI1699 1 None None None 17988206 Common - ISOVALERYL-COA DEHYDROGENASE BMEI1923 170 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 17987432 Common - NADH dehydrogenase subunit J BMEI1149 69 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 17987331 Common - Hypothetical Membrane Associated Protein BMEI1048 30 None None None 17988170 Common - MRP PROTEIN BMEI1887 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 17988304 Common - FOLYLPOLYGLUTAMATE SYNTHASE / DIHYDROFOLATE SYNTHASE BMEI2021 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 17986753 Common - ribosomal RNA methyltransferase BMEI0470 162 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 17987589 Common - PORIN BMEI1306 13 None None None 17987026 Common secE preprotein translocase subunit SecE BMEI0743 31 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 17988133 Common - HEME EXPORTER PROTEIN D BMEI1850 4 None None None 17987735 Common - RIBOSOMAL-PROTEIN-ALANINE ACETYLTRANSFERASE BMEI1452 137 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 17987187 Pathogen - hypothetical protein BMEI0904 1 None None None 17987977 Common - hypothetical protein BMEI1694 4 None None None 17986535 Common - F0F1 ATP synthase subunit beta BMEI0251 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 17988012 Common - MERCURIC RESISTANCE OPERON REGULATORY PROTEIN BMEI1729 18 COG0789 SoxR, Predicted transcriptional regulators Transcription 17986622 Common tolB translocation protein TolB BMEI0339 154 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 17986478 Common - Hypothetical Cytosolic Protein BMEI0194 32 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 17986955 Pathogen - hypothetical protein BMEI0672 1 None None None 17987366 Common - SEC-INDEPENDENT PROTEIN TRANSLOCASE PROTEIN TATC BMEI1083 204 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 17987505 Common - hypothetical protein BMEI1222 8 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 17986838 Pathogen - hypothetical protein BMEI0555 1 None None None 17986560 Common - HEAT SHOCK PROTEIN 15 BMEI0277 113 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 17987070 Common recA recombinase A BMEI0787 244 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 17988208 Common - acetyl-CoA carboxylase alpha chain / propionyl-CoA carboxylase alpha chain BMEI1925 234 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 17988000 Common - TRANSCRIPTIONAL REGULATOR, ICLR FAMILY BMEI1717 101 COG1414 IclR, Transcriptional regulator Transcription 17987267 Common - BETA-(1-->2)GLUCAN EXPORT ATP-BINDING PROTEIN NDVA BMEI0984 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 17987751 Common - TLDD PROTEIN BMEI1468 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 17986517 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase BMEI0233 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 17986554 Common - GERANYLTRANSTRANSFERASE BMEI0270 240 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 17988061 Common - TRANSPORTER BMEI1778 133 COG2860 COG2860, Predicted membrane protein Function unknown 17987474 Common - SERINE HYDROXYMETHYLTRANSFERASE BMEI1191 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 161511124 Common thiG thiazole synthase BMEI1735 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 17987415 Common - ATPase of the PP superfamily BMEI1132 142 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 17988211 Common - ENOYL-COA HYDRATASE BMEI1928 59 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 17986569 Common - putative nucleotide-binding protein BMEI0286 41 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 17988237 Common - ABC TRANSPORTER SUBSTRATE BINDING PROTEIN BMEI1954 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 17986686 Common - MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN MARC BMEI0403 30 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 17987923 Common - PHOSPHOHYDROLASE (MUTT/NUDIX FAMILY PROTEIN) BMEI1640 14 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 17987953 Common - ARSENATE REDUCTASE BMEI1670 71 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 17987182 Common - PHAGE-RELATED DNA BINDING PROTEIN BMEI0899 39 COG3617 COG3617, Prophage antirepressor Transcription 17986446 Common sdhB succinate dehydrogenase iron-sulfur subunit BMEI0162 192 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 17987245 Common - membrane lipoprotein lipid attachment site containing protein BMEI0962 24 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 17987515 Common - L-LACTATE PERMEASE BMEI1232 95 COG1620 LldP, L-lactate permease Energy production and conversion 17987384 Common - hypothetical protein BMEI1101 43 COG3313 COG3313, Predicted Fe-S protein General function prediction only 17987275 Common - ARSENATE REDUCTASE BMEI0992 105 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 17986462 Common - hypothetical protein BMEI0178 15 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 17987652 Common - PROTEIN YBIS PRECURSOR BMEI1369 69 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 17987001 Common radC DNA repair protein RadC BMEI0718 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 17986629 Common - SODIUM/BILE ACID COTRANSPORTER HOMOLOG, SBF FAMILY BMEI0346 96 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 17986722 Common - GLYCINE BETAINE/L-PROLINE TRANSPORT ATP-BINDING PROTEIN PROV BMEI0439 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 17986662 Common - PHOSPHINOTHRICIN N-ACETYLTRANSFERASE BMEI0379 123 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 17986467 Common - COMPETENCE PROTEIN F BMEI0183 161 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 17987325 Common - cysteine desulfurase activator complex subunit SufB BMEI1042 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 17986972 Common - ACYL-COA DEHYDROGENASE, SHORT-CHAIN SPECIFIC BMEI0689 160 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 17987914 Common - TRANSCRIPTIONAL REGULATOR, TETR FAMILY BMEI1631 59 COG1309 AcrR, Transcriptional regulator Transcription 17987762 Pathogen - hypothetical protein BMEI1479 1 None None None 17987091 Common - TRANSCRIPTIONAL REGULATOR, MERR FAMILY BMEI0808 103 COG0789 SoxR, Predicted transcriptional regulators Transcription 17987494 Common - GENERAL L-AMINO ACID-BINDING PERIPLASMIC PROTEIN AAPJ PRECURSOR BMEI1211 122 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 17986904 Common - pyridoxal phosphate biosynthetic protein PdxJ BMEI0621 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 17987148 Common - NITROGEN REGULATION PROTEIN NTRB BMEI0865 223 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 17987673 Common - D-RIBOSE-BINDING PERIPLASMIC PROTEIN PRECURSOR BMEI1390 94 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 17987166 Common - MULTIPLE ANTIBIOTIC RESISTANCE PROTEIN MARC BMEI0883 159 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 17987203 Common mazG nucleoside triphosphate pyrophosphohydrolase BMEI0920 155 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 17986402 Common - INTEGRAL MEMBRANE PROTEIN BMEI0118 67 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 17987869 Common - PROLINE RACEMASE BMEI1586 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 17986503 Common - MALONATE-SEMIALDEHYDE DEHYDROGENASE (ACYLATING) / METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE (ACYLATING) BMEI0219 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 17986600 Common - INTEGRAL MEMBRANE PROTEIN BMEI0317 117 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 17986544 Common - HIGH-AFFINITY BRANCHED-CHAIN AMINO ACID TRANSPORT ATP-BINDING PROTEIN BRAF BMEI0260 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 17986333 Common - COBS PROTEIN BMEI0049 67 COG0714 COG0714, MoxR-like ATPases General function prediction only 17988180 Pathogen - hypothetical protein BMEI1897 1 None None None 17988175 Pathogen - Hypothetical cytosolic protein (cysteine-rich) BMEI1892 2 None None None 17986311 Common - L-SORBOSE DEHYDROGENASE [FAD] BMEI0027 83 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 17986697 Common - PUTRESCINE TRANSPORT SYSTEM PERMEASE PROTEIN POTI BMEI0414 197 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 17986487 Common - ACETYLTRANSFERASE BMEI0203 13 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 17987660 Common - TRANSCRIPTION ELONGATION FACTOR GREB BMEI1377 119 COG0782 GreA, Transcription elongation factor Transcription 17987855 Common - Hypothetical Membrane Spanning Protein BMEI1572 38 COG3748 COG3748, Predicted membrane protein Function unknown 17987565 Common - AMINOMETHYLTRANSFERASE BMEI1282 113 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 17986936 Common - periplasmic component of efflux system BMEI0653 99 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 17986885 Common - hypothetical protein BMEI0602 20 None None None 17987032 Common rpoB DNA-directed RNA polymerase subunit beta BMEI0749 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 17987705 Common - TRANSPOSASE BMEI1422 45 None None None 17986850 Common - hypothetical protein BMEI0567 3 None None None 161511132 Common - betaine aldehyde dehydrogenase BMEI1382 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 17987448 Pathogen - Hypothetical Membrane Spanning Protein BMEI1165 1 None None None 17986452 Common - CELL DIVISION PROTEIN FTSK BMEI0168 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 17988328 Common hisB imidazoleglycerol-phosphate dehydratase BMEI2045 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 17986499 Common - dinucleoside polyphosphate hydrolase BMEI0215 114 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 17986459 Common - O-sialoglycoprotein endopeptidase BMEI0175 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 17988270 Common - PHOSPHATE TRANSPORT SYSTEM PERMEASE PROTEIN PSTA BMEI1987 221 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 161511131 Common - hypothetical protein BMEI1454 126 COG1678 COG1678, Putative transcriptional regulator Transcription 17987778 Common - LYSINE DECARBOXYLASE BMEI1495 151 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 17988051 Common - UROPORPHYRIN-III C-METHYLTRANSFERASE / PRECORRIN-2 OXIDASE / FERROCHELATASE BMEI1768 204 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 17987905 Pathogen - hypothetical protein BMEI1622 1 None None None 17987225 Pathogen - hypothetical protein BMEI0942 1 None None None 17986965 Common - POTASSIUM EFFLUX SYSTEM KEFA BMEI0682 193 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 17986614 Common - hypothetical protein BMEI0331 18 COG5317 COG5317, Uncharacterized protein conserved in bacteria Function unknown 17987995 Common - MANDELATE RACEMASE BMEI1712 132 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 17987607 Common - MEMBRANE ALANINE AMINOPEPTIDASE BMEI1324 160 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 17987523 Common - phosphoribosylaminoimidazole synthetase BMEI1240 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 17987951 Common hisD histidinol dehydrogenase BMEI1668 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 17986307 Common - 3-HYDROXYBUTYRYL-COA DEHYDRATASE BMEI0023 157 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 17988293 Common infC translation initiation factor IF-3 BMEI2010 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 17987636 Common - hypothetical protein BMEI1353 9 COG5436 COG5436, Predicted integral membrane protein Function unknown 17986706 Common - RESPONSE REGULATOR CTRA BMEI0423 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 17988227 Common rpsT 30S ribosomal protein S20 BMEI1944 185 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 17988024 Pathogen - hypothetical protein BMEI1741 1 None None None 17987545 Common - Hypothetical Membrane Spanning Protein BMEI1262 102 COG0795 COG0795, Predicted permeases General function prediction only 17988141 Common - PHOSPHINOTHRICIN N-ACETYLTRANSFERASE BMEI1858 122 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 17987580 Common - DNA-directed RNA polymerase subunit omega BMEI1297 115 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 17987423 Common - prolyl-tRNA synthetase BMEI1140 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 17987233 Common - PHOSPHOHISTIDINE PHOSPHATASE SIXA BMEI0950 66 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 17987557 Common - TRANSPORTER, LysE family BMEI1274 75 COG1279 COG1279, Lysine efflux permease General function prediction only 17987467 Common - SMALL PROTEIN A BMEI1184 36 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 17986355 Pathogen - hypothetical protein BMEI0071 2 None None None 17987077 Common - SPOU family of rRNA methylase BMEI0794 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 17987197 Common - PENICILLIN-BINDING PROTEIN 6 (D-ALANYL-D-ALANINE CARBOXYPEPTIDASE FRACTION C) BMEI0914 13 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 17986582 Common - hypothetical protein BMEI0299 19 COG5570 COG5570, Uncharacterized small protein Function unknown 17986638 Common - Glutamine amidotransferase class-II BMEI0355 66 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 17987044 Common rpsS 30S ribosomal protein S19 BMEI0761 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 17987661 Common - L-ASPARAGINASE II BMEI1378 46 COG4448 AnsA, L-asparaginase II Amino acid transport and metabolism 17987617 Common - CYTOCHROME C-TYPE BIOGENESIS PROTEIN CYCH BMEI1334 35 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 17986927 Common - UREASE ACCESSORY PROTEIN UREG BMEI0644 138 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 17988152 Common - HOMOSERINE/HOMOSERINE LACTONE EFFLUX PROTEIN BMEI1869 117 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 17988189 Common - PHOSPHOHYDROLASE (MUTT/NUDIX FAMILY PROTEIN) BMEI1906 102 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 17986320 Common - COBW PROTEIN BMEI0036 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 17988127 Common - hypothetical protein BMEI1844 10 None None None 17986385 Common - CYSTEINE SYNTHASE A BMEI0101 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 17986521 Common - Hypothetical Cytosolic Protein BMEI0237 4 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 17986340 Common rpmB 50S ribosomal protein L28 BMEI0056 152 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 17988163 Pathogen - Hypothetical Membrane Spanning Protein BMEI1880 2 None None None 17987369 Common - Hypothetical Cytosolic Protein BMEI1086 121 COG1354 COG1354, Uncharacterized conserved protein Function unknown 17988120 Common - CELLOBIOSE-PHOSPHORYLASE BMEI1837 48 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 17987304 Common - MOLYBDOPTERIN-GUANINE DINUCLEOTIDE BIOSYNTHESIS PROTEIN B BMEI1021 36 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 17987158 Common clpX ATP-dependent protease ATP-binding subunit BMEI0875 231 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 17986727 Common - METHYLTRANSFERASE BMEI0444 17 COG5459 COG5459, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 17986676 Common - D-RIBOSE-BINDING PERIPLASMIC PROTEIN PRECURSOR BMEI0393 107 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 17986703 Common - OXIDOREDUCTASE BMEI0420 187 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 17987783 Common - hypothetical protein BMEI1500 33 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 17987645 Common - hypothetical protein BMEI1362 13 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 17986895 Common - hypothetical protein BMEI0612 3 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 17986318 Common - N-ACYL-L-AMINO ACID AMIDOHYDROLASE BMEI0034 84 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 17988341 Common aroE shikimate 5-dehydrogenase BMEI2058 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 17988146 Common - LOW MOLECULAR WEIGHT PHOSPHOTYROSINE PROTEIN PHOSPHATASE BMEI1863 140 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 17988240 Common - 3-oxoacyl-(acyl carrier protein) synthase I BMEI1957 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 17987288 Common - hypothetical protein BMEI1005 2 None None None 17986699 Pathogen - hypothetical protein BMEI0416 1 None None None 17987372 Common argS arginyl-tRNA synthetase BMEI1089 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 17987895 Common - Na+ DRIVEN MULTIDRUG EFFLUX PUMP BMEI1612 91 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 17988179 Pathogen - Hypothetical Membrane Spanning Protein BMEI1896 2 None None None 17987804 Common - ACYL-COA DEHYDROGENASE BMEI1521 144 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 17987179 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, LYSR FAMILY BMEI0896 174 COG0583 LysR, Transcriptional regulator Transcription 17987169 Common coaD phosphopantetheine adenylyltransferase BMEI0886 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 17987921 Common - putative oxidoreductase BMEI1638 225 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 17987539 Common ndk nucleoside diphosphate kinase BMEI1256 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 17986342 Common - EXTRACELLULAR SERINE PROTEASE BMEI0058 58 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 17987989 Pathogen - hypothetical protein BMEI1706 1 None None None 17987683 Common - TRANSPOSASE BMEI1400 50 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987540 Common - DINB PROTEIN BMEI1257 36 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 17987136 Common - hypothetical protein BMEI0853 29 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 17988111 Common - RIBONUCLEASE D BMEI1828 107 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 17987935 Common ureC urease subunit alpha BMEI1652 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 17988306 Common - ATP-DEPENDENT NUCLEASE SUBUNIT A BMEI2023 223 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 17987819 Common - hypothetical protein BMEI1536 6 None None None 17986648 Common - BIOPOLYMER TRANSPORT EXBB PROTEIN BMEI0365 149 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 17987491 Common - GENERAL L-AMINO ACID TRANSPORT ATP-BINDING PROTEIN AAPP BMEI1208 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 17986419 Common - OUTER MEMBRANE LIPOPROTEIN BMEI0135 8 None None None 17986410 Common - MUTATOR MUTT PROTEIN (7,8-DIHYDRO-8-OXOGUANINE-TRIPHOSPHATASE) (8-OXO-DGTPASE) BMEI0126 170 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 17987101 Common - Hypothetical Cytosolic Protein BMEI0818 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 17987599 Common - GLUTATHIONE S-TRANSFERASE BMEI1316 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 17988308 Common - MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE BMEI2025 178 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 17987896 Common - hypothetical protein BMEI1613 57 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 17987942 Pathogen - hypothetical protein BMEI1659 1 None None None 17986775 Common - OSMOLARITY SENSOR PROTEIN ENVZ BMEI0492 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 17987873 Pathogen - hypothetical protein BMEI1590 1 None None None 17986899 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase BMEI0616 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 17987390 Common - Hypothetical Cytosolic Protein BMEI1107 27 None None None 17986725 Pathogen - hypothetical protein BMEI0442 1 None None None 17986763 Common - peptidyl-tRNA hydrolase BMEI0480 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 17986483 Common - hypothetical protein BMEI0199 16 None None None 17986400 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, LYSR FAMILY BMEI0116 182 COG0583 LysR, Transcriptional regulator Transcription 17987229 Common - NAD(FAD)-utilizing dehydrogenase BMEI0946 122 COG2081 COG2081, Predicted flavoproteins General function prediction only 17988052 Common - hypothetical protein BMEI1769 118 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 17986796 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, LYSR FAMILY BMEI0513 188 COG0583 LysR, Transcriptional regulator Transcription 17986757 Common - CYTOCHROME B BMEI0474 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 17988101 Common - ATP-DEPENDENT HELICASE HRPB BMEI1818 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 17988193 Common recR recombination protein RecR BMEI1910 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 17988202 Common - ACYLTRANSFERASE BMEI1919 21 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 17988249 Common - hypothetical protein BMEI1966 43 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 17988077 Common ihfB integration host factor subunit beta BMEI1794 205 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 17987471 Common - riboflavin synthase subunit alpha BMEI1188 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 17986518 Common - Hypothetical Cytosolic Protein BMEI0234 45 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 17987508 Pathogen - hypothetical protein BMEI1225 1 None None None 17987039 Common rpsJ 30S ribosomal protein S10 BMEI0756 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 17986804 Pathogen - hypothetical protein BMEI0521 1 None None None 161511140 Common - glutathione reductase BMEI0972 247 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 17986429 Common - dihydrolipoamide dehydrogenase BMEI0145 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 17988217 Common - PERIPLASMIC OLIGOPEPTIDE-BINDING PROTEIN PRECURSOR BMEI1934 151 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 17986590 Common - propionate-CoA ligase BMEI0307 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 17987771 Common - amidophosphoribosyltransferase BMEI1488 239 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 17987152 Common trkA potassium transporter peripheral membrane component BMEI0869 150 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 17987222 Pathogen - hypothetical protein BMEI0939 1 None None None 17987707 Common - TRANSPOSASE BMEI1424 79 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 17987074 Common - isocitrate dehydrogenase BMEI0791 62 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 17986394 Common - AGMATINASE BMEI0110 151 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 17987501 Common - similar to phage protein BMEI1218 11 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 17987294 Pathogen - hypothetical protein BMEI1011 1 None None None 17987360 Common - hypothetical protein BMEI1077 55 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 17988058 Common rph ribonuclease PH BMEI1775 181 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 17986652 Pathogen - hypothetical protein BMEI0369 2 None None None 17988272 Common - PHOSPHATE-BINDING PERIPLASMIC PROTEIN BMEI1989 130 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 17986811 Common - SODIUM-DEPENDENT PHOSPHATE TRANSPORT PROTEIN BMEI0528 58 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 17986599 Common - hypothetical protein BMEI0316 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 17986852 Common - manganese transport protein MntH BMEI0569 105 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 17986292 Common gidB glucose-inhibited division protein B BMEI0008 172 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 17986668 Common - Putative membrane-associated alkaline phosphatase BMEI0385 49 COG1238 COG1238, Predicted membrane protein Function unknown 17987124 Common - MOLYBDOPTERIN BIOSYNTHESIS MOEA PROTEIN BMEI0841 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 161511144 Common secG preprotein translocase subunit SecG BMEI0847 14 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 17987486 Common - RIBONUCLEASE D BMEI1203 123 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 17987405 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase BMEI1122 160 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 17987738 Common - THIO:disulfide Interchange Protein BMEI1455 52 COG4233 COG4233, Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis Posttranslational modification, protein turnover, chaperones / Energy production and conversion 17987630 Common - hypothetical protein BMEI1347 18 COG5437 COG5437, Predicted secreted protein Function unknown 17986327 Common aroB 3-dehydroquinate synthase BMEI0043 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 17987418 Pathogen - hypothetical protein BMEI1135 2 None None None 17987590 Common - INTEGRASE BMEI1307 200 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 17988041 Common - TRANSCRIPTIONAL ACTIVATOR, LUXR FAMILY BMEI1758 45 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 17988256 Common - CBS domain containing protein BMEI1973 216 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 17987529 Common - Hypothetical Cytosolic Protein BMEI1246 8 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 17987313 Common - PROTEIN-L-ISOASPARTATE O-METHYLTRANSFERASE BMEI1030 160 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 17987118 Common lpxB lipid-A-disaccharide synthase BMEI0835 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 17987726 Common - 2-HALOALKANOIC ACID DEHALOGENASE I BMEI1443 51 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 17988317 Common - SENSOR PROTEIN CHVG BMEI2034 77 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 17988122 Common - SULFATE TRANSPORT SYSTEM PERMEASE PROTEIN CYSW BMEI1839 194 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 17988168 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, LYSR FAMILY BMEI1885 182 COG0583 LysR, Transcriptional regulator Transcription 17987439 Common - NADH dehydrogenase subunit C BMEI1156 176 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 17987829 Common - F0F1 ATP synthase subunit A BMEI1546 74 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 17986750 Common - coproporphyrinogen III oxidase BMEI0467 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 17986982 Common - hypothetical protein BMEI0699 5 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 17987785 Common - ALKALINE PHOSPHATASE LIKE PROTEIN BMEI1502 134 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 17988224 Common recF recombination protein F BMEI1941 160 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 17987825 Common rnhB ribonuclease HII BMEI1542 207 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 17987455 Common - CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX15 BMEI1172 47 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 17987555 Common cysS cysteinyl-tRNA synthetase BMEI1272 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 17986513 Common - Hypothetical Membrane Spanning Protein BMEI0229 91 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 17987712 Common - TRANSTHYRETIN-LIKE PROTEIN PRECURSOR BMEI1429 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 17987575 Common - FOSMIDOMYCIN RESISTANCE PROTEIN BMEI1292 107 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 17986420 Common - PUTATIVE ATPASE N2B BMEI0136 102 COG1485 COG1485, Predicted ATPase General function prediction only 17988129 Common - EXSF PROTEIN BMEI1846 28 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 17986790 Common - hypothetical protein BMEI0507 12 None None None 17987796 Common - CHAPERONE PROTEIN DNAJ BMEI1513 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 17986974 Common - hypothetical protein BMEI0691 10 None None None 17988264 Common - AMINOPEPTIDASE T BMEI1981 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 17987064 Common - DNA-directed RNA polymerase subunit alpha BMEI0781 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 17987430 Common - NADH dehydrogenase subunit L BMEI1147 208 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 17988004 Common - SARCOSINE OXIDASE DELTA SUBUNIT BMEI1721 33 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 17988283 Common - PHOSPHATIDYLETHANOLAMINE N-METHYLTRANSFERASE / PHOSPHATIDYL-N-METHYLETHANOLAMINE N-METHYLTRANSFERASE BMEI2000 42 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 17987987 Pathogen - hypothetical protein BMEI1704 1 None None None 17987083 Common - PROPIONYL-COA CARBOXYLASE ALPHA CHAIN, MITOCHONDRIAL BMEI0800 239 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 17987811 Common - SUA5 PROTEIN BMEI1528 232 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 17987958 Common - hypothetical protein BMEI1675 10 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 17987713 Common - ureidoglycolate hydrolase BMEI1430 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 17988294 Common - 2-HYDROXYMUCONIC SEMIALDEHYDE HYDROLASE BMEI2011 45 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 17988334 Common - SMR/MUTS FAMILY PROTEIN BMEI2051 86 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 17987033 Common - DNA-directed RNA polymerase subunit beta' BMEI0750 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 17988049 Common - SULFITE REDUCTASE (FERREDOXIN) BMEI1766 161 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 17986433 Common trmD tRNA (guanine-N(1)-)-methyltransferase BMEI0149 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 17987338 Common - PENICILLIN-BINDING PROTEIN 1A BMEI1055 202 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 17987887 Common - 5-aminolevulinate synthase BMEI1604 191 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 17986625 Common - CELL CYCLE PROTEIN MESJ BMEI0342 121 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 17986842 Common - 5,10-METHYLENETETRAHYDROFOLATE REDUCTASE BMEI0559 143 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 17987845 Pathogen - hypothetical protein BMEI1562 1 None None None 17988312 Common - S-adenosyl-L-homocysteine hydrolase BMEI2029 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 17987375 Common - hypothetical protein BMEI1092 32 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 17987856 Common - TRANSCRIPTIONAL REGULATORY PROTEIN, LYSR FAMILY BMEI1573 137 COG0583 LysR, Transcriptional regulator Transcription 17988002 Common - SARCOSINE OXIDASE GAMMA SUBUNIT BMEI1719 21 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 161511167 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase BMEI0026 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17987478 Common - Hypothetical Membrane Spanning Protein BMEI1195 12 None None None 17987269 Common - SEC-INDEPENDENT PROTEIN TATD BMEI0986 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 17986368 Common - DIAMINOPIMELATE DECARBOXYLASE BMEI0084 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 17986448 Common - PROBABLE LACTOYLGLUTATHIONE LYASE BMEI0164 64 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 17986506 Common - CARBONIC ANHYDRASE BMEI0222 151 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 17986766 Common - ribose-phosphate pyrophosphokinase BMEI0483 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 17988310 Common - ALKALINE PHOSPHATASE SYNTHESIS SENSOR PROTEIN PHOR BMEI2027 219 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 17987005 Common - hypothetical protein BMEI0722 10 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 17986407 Common - PEPTIDYL-PROLYL CIS-TRANS ISOMERASE BMEI0123 122 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 17987162 Pathogen - hypothetical protein BMEI0879 1 None None None 17986694 Common - PUTRESCINE-BINDING PERIPLASMIC PROTEIN BMEI0411 129 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 17987832 Common - DNAK PROTEIN BMEI1549 225 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 17986556 Common rpmF 50S ribosomal protein L32 BMEI0272 121 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 17986636 Common - PROLINE/BETAINE TRANSPORTER BMEI0353 155 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 17986612 Common - thiamine-phosphate pyrophosphorylase BMEI0329 63 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 161511127 Common - F0F1 ATP synthase subunit B BMEI1543 19 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 17987971 Common - hypothetical protein BMEI1688 2 None None None 17987802 Common - phosphoribosylamine--glycine ligase BMEI1519 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 17987870 Pathogen - hypothetical protein BMEI1587 1 None None None 17987248 Common - TOLUENE TOLERANCE PROTEIN TTG2B BMEI0965 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 17986994 Pathogen - hypothetical protein BMEI0711 2 None None None 17987012 Common - TRANSPORTER BMEI0729 22 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 17988235 Common - 2-hydroxyacid dehydrogenase BMEI1952 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 17987543 Common - DNA polymerase III subunit chi BMEI1260 38 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 17986959 Common - hypothetical protein BMEI0676 36 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 161511117 Common - S-adenosylmethionine synthetase BMEI1970 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 17988091 Common - NIFU PROTEIN BMEI1808 96 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 17987273 Common - D-ALANYL-D-ALANINE CARBOXYPEPTIDASE BMEI0990 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 17988030 Common - ALDEHYDE DEHYDROGENASE BMEI1747 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 17987979 Common - Hypothetical Membrane Spanning Protein BMEI1696 16 None None None 17987916 Common - Hydrolases of the alpha/beta superfamily BMEI1633 26 COG4757 COG4757, Predicted alpha/beta hydrolase General function prediction only 17987066 Common - PROTEASE DO BMEI0783 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 17987093 Common - hypothetical protein BMEI0810 88 COG1434 COG1434, Uncharacterized conserved protein Function unknown 17988039 Pathogen - hypothetical protein BMEI1756 1 None None None 17986493 Common nadD nicotinic acid mononucleotide adenyltransferase BMEI0209 174 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 17987760 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase BMEI1477 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 17987452 Common rpsI 30S ribosomal protein S9 BMEI1169 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 17988066 Common - Hypothetical Membrane Spanning Protein BMEI1783 19 COG5488 COG5488, Integral membrane protein Function unknown 17986848 Common - ANHYDRO-N-ACETYLMURAMYL-TRIPEPTIDE AMIDASE BMEI0565 112 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 17987201 Common - Nitroreductase family BMEI0918 28 COG0778 NfnB, Nitroreductase Energy production and conversion 17987327 Common - ALPHA/BETA HYDROLASE BMEI1044 86 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 17988161 Common - SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE BMEI1878 20 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 17988014 Common - Diguanylate cyclase/phosphodiesterase domain 2 (EAL) BMEI1731 192 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 17988242 Common - METHYLTRANSFERASE BMEI1959 53 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 17986526 Common leuS leucyl-tRNA synthetase BMEI0242 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 17988084 Common - DNA mismatch repair protein BMEI1801 199 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 17987638 Common - Hypothetical Cytosolic Protein BMEI1355 25 COG5447 COG5447, Uncharacterized conserved protein Function unknown 17986471 Common - TRANSPORTER, DME FAMILY BMEI0187 8 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 17986946 Common - D-RIBOSE-BINDING PERIPLASMIC PROTEIN PRECURSOR BMEI0663 29 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 17987041 Common rplD 50S ribosomal protein L4 BMEI0758 214 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 17987691 Common - TRANSPOSASE BMEI1408 47 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 17987024 Common - 23S ribosomal RNA methyltransferase BMEI0741 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 17987503 Common - hypothetical protein BMEI1220 7 None None None 17988254 Common - TRANSCRIPTIONAL REGULATOR BMEI1971 40 COG1396 HipB, Predicted transcriptional regulators Transcription 17987929 Common - ACRIFLAVIN RESISTANCE PROTEIN E BMEI1646 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 17986934 Common - Hypothetical Cytosolic Protein BMEI0651 38 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 17987615 Common - CYTOCHROME C-TYPE BIOGENESIS PROTEIN CYCK BMEI1332 138 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 17988221 Common - OLIGOPEPTIDE TRANSPORT ATP-BINDING PROTEIN OPPD BMEI1938 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 17986376 Common - ADENOSYLCOBALAMIN-DEPENDENT DIOL DEHYDRATASE GAMMA SUBUNIT BMEI0092 131 COG2096 COG2096, Uncharacterized conserved protein Function unknown 17986993 Common - hypothetical protein BMEI0710 6 None None None 17986515 Common - NAD-SPECIFIC GLUTAMATE DEHYDROGENASE BMEI0231 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 17987746 Common - cytochrome C oxidase assembly protein BMEI1463 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 17987386 Common - tRNA-dihydrouridine synthase A BMEI1103 210 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 17986832 Common - BENZOATE 1,2-DIOXYGENASE ALPHA SUBUNIT BMEI0549 83 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 17988135 Common - HEME EXPORTER PROTEIN B BMEI1852 74 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 17987600 Pathogen - hypothetical protein BMEI1317 1 None None None 17986782 Common - SOLUBLE LYTIC MUREIN TRANSGLYCOSYLASE BMEI0499 12 None None None 17986605 Common rpmE 50S ribosomal protein L31 BMEI0322 113 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 17986928 Common - UREASE ACCESSORY PROTEIN UREF BMEI0645 42 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 161511114 Common hisH imidazole glycerol phosphate synthase subunit HisH BMEI2043 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 17986870 Common - COML, COMPETENCE LIPOPROTEIN BMEI0587 131 COG4105 ComL, DNA uptake lipoprotein General function prediction only 17987235 Common - hypothetical protein BMEI0952 43 COG3768 COG3768, Predicted membrane protein Function unknown 17986963 Common - bifunctional preprotein translocase subunit SecD/SecF BMEI0680 206 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 17987663 Common - choline dehydrogenase BMEI1380 90 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 17986690 Pathogen - hypothetical protein BMEI0407 1 None None None 17987647 Common - TRANSCRIPTIONAL REGULATORY PROTEIN MUCR BMEI1364 33 COG4957 COG4957, Predicted transcriptional regulator Transcription 17986571 Common - ABC TRANSPORTER ATP-BINDING PROTEIN UUP BMEI0288 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 17986353 Common - OUTER MEMBRANE LIPOPROTEINS CARRIER PROTEIN PRECURSOR BMEI0069 35 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 17988118 Common - N-methyl-D-aspartate receptor BMEI1835 105 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 17987469 Common nusB transcription antitermination protein NusB BMEI1186 172 COG0781 NusB, Transcription termination factor Transcription 17987195 Common - hypothetical protein BMEI0912 179 COG0759 COG0759, Uncharacterized conserved protein Function unknown 17986681 Common - DEOXYRIBONUCLEOSIDE REGULATOR / DIHYDROXYACETONE KINASE BMEI0398 94 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 17986879 Common - DNA HELICASE II BMEI0596 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 17986919 Common - COBALT TRANSPORT ATP-BINDING PROTEIN CBIO BMEI0636 242 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 17986957 Common - SULFATE TRANSPORT SYSTEM PERMEASE PROTEIN CYST BMEI0674 231 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 17986789 Common - TRANSPORTER, DME FAMILY BMEI0506 115 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 17986642 Common - periplasmic component of efflux system BMEI0359 176 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 17987460 Common - PUTATIVE COLANIC BIOSYNTHESIS UDP-GLUCOSE LIPID CARRIER TRANSFERASE BMEI1177 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 17986666 Common - 5-METHYLCYTOSINE-SPECIFIC RESTRICTION ENZYME A BMEI0383 98 COG1403 McrA, Restriction endonuclease Defense mechanisms 17986649 Common - hypothetical protein BMEI0366 3 None None None 17986580 Common - Hypothetical Cytosolic Protein BMEI0297 13 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 17987773 Common - CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE BMEI1490 142 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 17988150 Common - FLORFENICOL RESISTANCE PROTEIN BMEI1867 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 17986501 Common - hypothetical protein BMEI0217 19 COG3619 COG3619, Predicted membrane protein Function unknown 17987205 Common - SODIUM/BILE ACID COTRANSPORTER HOMOLOG, SBF FAMILY BMEI0922 58 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 17987357 Common - PHYTOENE SYNTHASE BMEI1074 60 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 17987620 Common - TRANSCRIPTIONAL REGULATORY PROTEIN PHOP BMEI1337 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 17987964 Common - hypothetical protein BMEI1681 7 None None None 17988158 Common - Hypothetical Cytosolic Protein BMEI1875 66 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 17986720 Common - DIPEPTIDE TRANSPORT ATP-BINDING PROTEIN DPPD BMEI0437 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 17986903 Common - hypothetical protein BMEI0620 8 None None None 17986344 Pathogen - hypothetical protein BMEI0060 1 None None None 17987658 Pathogen - hypothetical protein BMEI1375 2 COG2336 MazE, Growth regulator Signal transduction mechanisms 17986309 Common - L-sorbose dehydrogenase (FAD) BMEI0025 88 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 17986745 Common - PHOSPHOHYDROLASE (MUTT/NUDIX FAMILY PROTEIN) BMEI0462 126 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 17987933 Common - UREASE ACCESSORY PROTEIN UREF BMEI1650 47 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 17986673 Common - Hypothetical Cytosolic Protein BMEI0390 6 COG5591 COG5591, Uncharacterized conserved protein Function unknown 17988070 Common - putative sigma54 modulation protein / SSU ribosomal protein S30P BMEI1787 55 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 17986469 Common - BETA-UREIDOPROPIONASE BMEI0185 199 COG0388 COG0388, Predicted amidohydrolase General function prediction only 17986335 Pathogen - hypothetical protein BMEI0051 1 None None None 17988279 Common - glutathione synthetase BMEI1996 137 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 17987900 Common - O-succinylhomoserine sulfhydrylase BMEI1617 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 17986542 Common - HIGH-AFFINITY BRANCHED-CHAIN AMINO ACID TRANSPORT SYSTEM PERMEASE PROTEIN LIVH BMEI0258 150 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 17986921 Common - hypothetical protein BMEI0638 10 None None None 17986457 Common - YciI-like protein BMEI0173 47 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 17988173 Common - TRANSPORTER BMEI1890 89 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 17987241 Common - THIOREDOXIN REDUCTASE BMEI0958 51 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 17986399 Common - ASPARAGINE-BINDING PERIPLASMIC PROTEIN PRECURSOR BMEI0115 103 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 17986654 Common - RNA polymerase sigma factor BMEI0371 166 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 17986286 Common - CYTOCHROME FUNCTIONING/ASSEMBLY RELATED PROTEIN BMEI0002 97 COG1981 COG1981, Predicted membrane protein Function unknown 17986336 Common - hypothetical protein BMEI0052 8 None None None 17986716 Common - PERIPLASMIC DIPEPTIDE TRANSPORT PROTEIN PRECURSOR BMEI0433 202 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 17987180 Common - GLUTARYL-COA DEHYDROGENASE BMEI0897 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 17986312 Common - L-SORBOSE DEHYDROGENASE [FAD] BMEI0028 87 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 17987223 Common - xanthine-guanine phosphoribosyltransferase BMEI0940 70 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 17987864 Common - TRIPARTITE TRANSPORTER, SMALL SUBUNIT BMEI1581 72 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 17986533 Common - F0F1 ATP synthase subunit alpha BMEI0249 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 17986860 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase BMEI0577 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 17986619 Common - TOLQ PROTEIN BMEI0336 133 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 17987627 Common - hypothetical protein BMEI1344 26 COG5448 COG5448, Uncharacterized conserved protein Function unknown 17988026 Common - ABC TRANSPORTER ATP-BINDING PROTEIN BMEI1743 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 17987563 Common - Hypothetical Cytosolic Protein BMEI1280 6 None None None 17988148 Common - hypothetical protein BMEI1865 37 COG3339 COG3339, Uncharacterized conserved protein Function unknown 17986869 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase BMEI0586 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 17986450 Common - ACYL-COA THIOESTERASE II BMEI0166 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 17987907 Common - PHOSPHATE REGULON SENSOR PROTEIN PHOR BMEI1624 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 17987605 Common - TRANSPORTER, MFS superfamily BMEI1322 73 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 17987018 Common - hypothetical protein BMEI0735 21 None None None