Bacteroides fragilis NCTC 9343, complete genome NC_003228 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 60680256 Pathogen - hypothetical protein BF0697 1 None None None 60680547 Common - hypothetical protein BF1003 2 None None None 60681449 Common - putative MatE-family transmembrane protein BF1960 179 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60683425 Common rpsN 30S ribosomal protein S14 BF3990 211 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 60682385 Common - putative CTP pyrophosphohydrolase BF2916 130 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 60680762 Common - conserved hypothetical transmembrane protein found on conjugate transposon BF1242 3 None None None 60681243 Common - hypothetical protein BF1751 2 None None None 60682477 Common - hypothetical protein BF3007 6 None None None 60683330 Common clpX ATP-dependent protease ATP-binding subunit BF3893 227 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 60682315 Pathogen - hypothetical protein BF2845 1 None None None 60680924 Common - putative anti-sigma factor BF1413 38 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60683563 Common sufE putative SufE Fe/S-cluster-related protein BF4142 98 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 60682225 Common - putative two component system response regulator BF2753 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 60680875 Pathogen - hypothetical protein BF1359 1 None None None 60682801 Common pncB nicotinate phosphoribosyltransferase BF3334 68 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 60682029 Common - putative bifunctional CbiF/CbiG cobalamin biosynthesis protein BF2549 201 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 60681247 Common - hypothetical protein BF1755 3 None None None 60680681 Common - hypothetical protein BF1156 63 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 60681337 Pathogen - hypothetical protein BF1846 1 None None None 60681605 Pathogen - hypothetical protein BF2124 1 None None None 60680702 Pathogen - hypothetical protein BF1177 1 None None None 60683374 Common - hypothetical protein BF3937 10 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 60679697 Common - putative two-component response regulator BF0101 145 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 60682414 Common - putative sigma factor BF2944 74 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60679898 Pathogen - hypothetical protein BF0309 1 None None None 60682098 Common - ferredoxin BF2619 143 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 60683167 Common - putative exported uslfatase BF3722 89 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60679863 Common - putative hemolysin A BF0270 25 COG3176 COG3176, Putative hemolysin General function prediction only 60682455 Common - putative ABC transport system, exported protein BF2985 16 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60679649 Pathogen - hypothetical protein BF0052 1 None None None 60680939 Common - putative ABC transporter component protein BF1430 122 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 60680543 Common - hypothetical protein BF0999 6 None None None 60682009 Common - hypothetical protein BF2529 111 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 60681651 Common - putative transport-related membrane protein BF2172 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 60683079 Pathogen - hypothetical protein BF3629 1 None None None 60681369 Common - putative DNA-binding cyclic-nucleotide binding protein BF1878 30 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 60682347 Common tsr25 tyrosine site-specific recombinase BF2877 6 None None None 60680989 Pathogen - putative transmembrane protein BF1487 1 None None None 60682408 Common - diphosphate--fructose-6-phosphate 1-phosphotransferase BF2938 138 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 60683135 Common - putative transferase BF3689 10 None None None 60681954 Common - hypothetical protein BF2474 37 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 60682467 Pathogen - putative lipoprotein BF2997 1 None None None 60679705 Common - hypothetical protein BF0109 25 COG1694 MazG, Predicted pyrophosphatase General function prediction only 60683186 Common ppnK inorganic polyphosphate/ATP-NAD kinase BF3741 241 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 60681484 Pathogen - hypothetical protein BF1996 1 None None None 60681827 Pathogen - hypothetical protein BF2347B 1 None None None 60679608 Common - putative ABC transporter ATP-binding protein BF0011 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 60683432 Common rpsC 30S ribosomal protein S3 BF3997 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 60680821 Common menB naphthoate synthase BF1303 178 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 60682613 Common - putative lipoprotein BF3144 4 None None None 60683736 Common - hypothetical protein BF4324 13 None None None 60679642 Common - conserved hypothetical lipoprotein BF0045 7 None None None 60682202 Common - hypothetical protein BF2729 7 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 60680954 Pathogen - hypothetical protein BF1448 1 None None None 60680793 Common - putative transmembrane protein BF1274 43 COG2962 RarD, Predicted permeases General function prediction only 60681465 Pathogen - hypothetical protein BF1977 1 None None None 60681828 Pathogen - hypothetical protein BF2348 1 None None None 60682451 Common - putative exonuclease BF2981 160 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 60679901 Common - putative transmembrane acyltransferase protein BF0312 99 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 60683368 Common - putative ribosomal large subunit pseudouridine synthase BF3931 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 60681733 Common - hypothetical protein BF2254 8 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60683316 Common - putative transposase BF3879 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 60680148 Common - putative transmembrane protein BF0582 143 COG0628 PerM, Predicted permease General function prediction only 60682868 Common - hypothetical protein BF3406 4 None None None 60683203 Common - hypothetical protein BF3757 7 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60683776 Common - translation-associated GTPase BF4365 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 60683139 Common - hypothetical protein BF3693 4 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 60680573 Common - putative hypoxanthine guanine phosphoribosyltransferase BF1031 151 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 60681623 Common - putative 2,5-dichloro-2,5-cyclohexadiene-1,4-diol dehydrogenase BF2144 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 60682154 Common ansA putative L-asparaginase I BF2680 134 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 60682231 Common sigA putative sigma factor A BF2759 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 60682831 Common - putative copper/silver resistance-related transport membrane protein BF3368 175 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 60681103 Common - putative outer membrane protein BF1607 18 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60680736 Pathogen - hypothetical protein BF1213 1 None None None 60681107 Common - putative FtsX-related transmembrane transport protein BF1611 22 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60683066 Common - hypothetical protein BF3616 41 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 60682658 Common - hypothetical protein BF3189 8 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 60683384 Common - putative transmembrane MotA/TolQ/ExbB proton channel family protein BF3947 23 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 60680780 Pathogen - hypothetical protein BF1260 1 None None None 60679743 Common - putative dihydrodipicolinate reductase BF0147 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 60680234 Common cls putative cardiolipin synthetase BF0675 151 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 60683294 Common - putative transport related membrane protein BF3852 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60680110 Pathogen - hypothetical protein BF0541 1 None None None 60680455 Pathogen - hypothetical protein BF0906 2 COG4105 ComL, DNA uptake lipoprotein General function prediction only 60682504 Common - hypothetical protein BF3034 26 None None None 60682993 Common cmk putative cytidylate kinase BF3535 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 60681924 Pathogen - hypothetical protein BF2443 1 None None None 60683009 Common ilvD dihydroxy-acid dehydratase BF3551 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 60683588 Common - hypothetical protein BF4167 22 COG5368 COG5368, Uncharacterized protein conserved in bacteria Function unknown 60681965 Common ligA putative DNA ligase BF2485 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 60681974 Common - hypothetical protein BF2494 34 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 60682727 Common - hypothetical protein BF3257 5 None None None 60682407 Common - hypothetical protein BF2937 4 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 60680982 Pathogen - hypothetical protein BF1480 3 None None None 60682218 Common - V-type ATP synthase subunit D BF2745 10 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 60682687 Common - putative flavoprotein BF3218 48 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 60682680 Common - hypothetical protein BF3211 6 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 60682622 Common - hypothetical protein BF3153 7 None None None 60680836 Common oxyR redox-sensitive transcriptional activator BF1318 190 COG0583 LysR, Transcriptional regulator Transcription 60681072 Common ssb putative single-strand binding protein BF1571 211 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 60681193 Common - xanthine phosphoribosyltransferase BF1699 93 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 60680373 Pathogen - hypothetical protein BF0822 1 None None None 60683622 Common - putative glycosyl transferase BF4202 31 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 60682337 Pathogen - hypothetical protein BF2867 1 None None None 60681023 Pathogen mobA mobilisation protein A BF1522 1 None None None 60681719 Common - putative cation efflux-related membrane protein BF2240 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 60682147 Common trpB tryptophan synthase subunit beta BF2672 226 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 60682511 Common - hypothetical protein BF3041 3 None None None 60682220 Common - V-type ATP synthase subunit A BF2747 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 60680031 Common - putative transcriptional regulatory protein BF0454 20 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 60682482 Pathogen - hypothetical protein BF3012 1 None None None 60681608 Common - putative aldo/keto reductase BF2127 175 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 60683762 Common - putative peptidase BF4351 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 60679893 Common - putative exported carbohydrate-binding protein BF0302 29 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 60682997 Common - putative oxidoreductase BF3539 179 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 60679850 Common mraY putative UDP-N-acetylmuramoyl-pentapeptide:undecaprenyl-phosphate-ph osphatase BF0257 212 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 60682931 Pathogen - hypothetical protein BF3471 1 None None None 60680846 Pathogen - hypothetical protein BF1329 1 None None None 60680122 Common - hypothetical protein BF0553 80 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 60681100 Common - putative transmembrane protein BF1604 148 COG0628 PerM, Predicted permease General function prediction only 60680354 Common - putative secreted sulfatase BF0802 79 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60683407 Common - putative transmembrane DNA mismatch repair-like protein BF3972 193 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 60681315 Pathogen - putative transmembrane protein BF1823 1 None None None 60681839 Common - putative carbon-nitrogen hydrolase BF2359 178 COG0388 COG0388, Predicted amidohydrolase General function prediction only 60680245 Common - putative alpha-1,2-mannosidase precursor BF0686 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 60680640 Common - hypothetical protein BF1110 5 None None None 60682598 Common - hypothetical protein BF3129 8 None None None 60681661 Common - hypothetical protein BF2182 4 None None None 60683099 Pathogen - hypothetical protein BF3649A 1 None None None 60681969 Common - hypothetical protein BF2489 100 COG1262 COG1262, Uncharacterized conserved protein Function unknown 60680484 Common - putative zinc protease BF0935 175 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 60682667 Common - hypothetical protein BF3198 5 None None None 60681442 Common - putative LemA antigen-like protein BF1953 130 COG1704 LemA, Uncharacterized conserved protein Function unknown 60681239 Pathogen - hypothetical protein BF1747 1 None None None 60680318 Common - putative secreted glucosidase BF0763 11 COG3661 AguA, Alpha-glucuronidase Carbohydrate transport and metabolism 60681083 Pathogen - hypothetical protein BF1584 1 None None None 60682820 Pathogen - hypothetical protein BF3355 2 None None None 60682488 Common - putative rubrerythrin-like protein BF3018 24 COG1592 COG1592, Rubrerythrin Energy production and conversion 60681884 Pathogen - hypothetical protein BF2405 1 None None None 60681053 Common rmlC2 putative dTDP-4-dehydrorhamnose 3,5 epimerase BF1552 168 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 60679690 Common - putative transmembrane protein BF0094 93 COG1238 COG1238, Predicted membrane protein Function unknown 60682061 Pathogen - hypothetical protein BF2582 2 None None None 60680087 Common - putative outer membrane protein BF0518 10 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60681041 Pathogen - hypothetical protein BF1540 1 None None None 60681722 Common - putative MarC-family antibiotic resistance related membrane protein BF2243 77 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 60682263 Common - putative transmembrane protein BF2792 7 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 60680286 Pathogen - hypothetical protein BF0730 1 None None None 60680492 Common - hypothetical protein BF0943 76 COG1259 COG1259, Uncharacterized conserved protein Function unknown 60681393 Common wcfX putative LPS biosynthesis related UDP-glucuronic acid epimerase BF1903 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60681960 Common - hypothetical protein BF2480 52 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 60679680 Common - hypothetical protein BF0084 2 None None None 60681948 Common - putative ABC transport system, ATP-binding protein BF2468 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 60679759 Common - putative two-component system, response regulator protein BF0164 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 60681429 Common - hypothetical protein BF1940 6 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 60682178 Pathogen - hypothetical protein BF2705 1 None None None 60680684 Pathogen - putative DNA-binding protein BF1159 1 None None None 60679932 Common - putative DNA-binding protein BF0343 4 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 60680499 Common - hypothetical protein BF0951 6 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 60682393 Pathogen - hypothetical protein BF2923 2 None None None 60681817 Common - putative amylase BF2339 103 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 60679965 Common - hypothetical protein BF0379 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 60683326 Common - hypothetical protein BF3889 3 None None None 60680105 Common frrG putative outer membrane protein BF0536 30 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680250 Common - putative transcriptional regulator protein BF0691 95 COG0789 SoxR, Predicted transcriptional regulators Transcription 60681060 Common - hypothetical protein BF1559 2 None None None 60681648 Common - putative TetR-family transcriptional regulator BF2169 71 COG1309 AcrR, Transcriptional regulator Transcription 60682542 Pathogen - hypothetical protein BF3073 2 None None None 60679752 Common - putative AcrA/AcrE RND transport or HlyD secretion family protein BF0156 153 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60680249 Common - putative transmembrane peptidase BF0690 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 60682867 Common - hypothetical protein BF3405 84 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 60679987 Pathogen - hypothetical protein BF0404 1 None None None 60680166 Common - putative aminopeptidase BF0600 165 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 60683668 Pathogen - hypothetical protein BF4250 1 None None None 60683072 Common - putative dihydroneopterin aldolase BF3622 64 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 60681361 Common - hypothetical protein BF1870 4 None None None 60683217 Common - branched-chain amino acid aminotransferase BF3772 209 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 60683265 Pathogen - hypothetical protein BF3822 1 None None None 60679859 Pathogen - hypothetical protein BF0266 1 None None None 60681340 Common - hypothetical protein BF1849 4 None None None 60682981 Common thyA thymidylate synthase BF3523 139 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 60680028 Pathogen - hypothetical protein BF0451 3 None None None 60681707 Common atpC ATP synthase epsilon chain BF2228 137 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 60681561 Common - putative type II restriction enzyme BF2077 4 None None None 60682070 Common - putative LPS biosynthesis related glycosyltransferase BF2591 155 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 60680962 Common - putative DNA-binding protein BF1459 5 None None None 60682398 Common - putative K(+) transport-related membrane protein BF2928 132 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 60681394 Common wcfY putative LPS biosynthesis related UDP-glucose dehydrogenase BF1904 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 60679958 Common - putative FAD-binding oxidoreductase BF0370 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 60681204 Common - possible O-antigen related protein BF1710 22 COG2140 COG2140, Thermophilic glucose-6-phosphate isomerase and related metalloenzymes Carbohydrate transport and metabolism / General function prediction only 60679657 Common - hypothetical protein BF0061 3 None None None 60680898 Common - hypothetical protein BF1384 7 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 60683528 Common - putative transmembrane ferredoxin-like protein BF4104 88 COG0348 NapH, Polyferredoxin Energy production and conversion 60680620 Pathogen - hypothetical protein BF1088 1 None None None 60683496 Common - putative IstB IS21 family transposase protein BF4071 98 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 60679887 Pathogen - hypothetical protein BF0296 1 None None None 60683123 Common - putative transport related, membrane protein BF3674 146 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 60680450 Common - putative transmembrane protein BF0901 8 COG4758 COG4758, Predicted membrane protein Function unknown 60681174 Pathogen - hypothetical protein BF1680 1 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 60682925 Common - putative LPS biosynthesis related glycosyltransferase BF3464 176 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 60680302 Common - hypothetical protein BF0747 24 None None None 60680649 Common - putative modification enzyme of type III restriction-modification system BF1120 94 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 60681730 Pathogen - hypothetical protein BF2251 1 None None None 60680406 Common - hypothetical protein BF0855 18 None None None 60680437 Common mscL putative large-conductance mechanosensitive channel BF0886 132 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 60683494 Pathogen - hypothetical protein BF4069 2 None None None 60683147 Pathogen - hypothetical protein BF3701 1 None None None 60679880 Common - putative glycosylhydrolase BF0287 54 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 60679811 Common - hypothetical protein BF0217 41 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 60679821 Common - putative exported alpha-galactosidase BF0227 20 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 60680298 Common - possible capsular polysaccharide related protein BF0742 13 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60681843 Common - putative cytochrome C biogenesis-related protein BF2363 165 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 60681814 Common - hypothetical protein BF2336 17 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 60682527 Common - putative methenyltetrahydrofolate cyclohydrolase BF3058 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 60679985 Pathogen - hypothetical protein BF0402 1 None None None 60681570 Common - putative transmembrane cation-transporting ATPase BF2086 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 60680756 Pathogen - conserved hypothetical protein found in conjugate transposon BF1236 1 None None None 60680975 Pathogen - hypothetical protein BF1473 1 None None None 60679877 Common - putative exported glycosylhydrolase BF0284 71 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60682970 Common - putative metal resistance related trasport membrane protein BF3512 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 60682629 Pathogen - hypothetical protein BF3160 1 None None None 60682493 Pathogen - hypothetical protein BF3023 1 None None None 60683109 Common - hypothetical protein BF3660 102 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 60680630 Pathogen - hypothetical protein BF1099 1 None None None 60680389 Common aroE putative shikimate 5-dehydrogenase BF0838 212 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 60682306 Pathogen - hypothetical protein BF2836 1 None None None 60682662 Common - putative lipoprotein BF3193 160 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60680743 Common - hypothetical protein BF1220 16 None None None 60683416 Common infA translation initiation factor IF-1 BF3981 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 60680196 Common - hypothetical protein BF0634 91 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 60681213 Common - hypothetical protein BF1721 6 None None None 60682782 Common - putative lipoprotein BF3314 2 None None None 60682952 Common - putative peptidase BF3493 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 60682423 Common - glucosamine-6-phosphate deaminase-like protein BF2953 87 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 60681017 Pathogen - hypothetical protein BF1516 1 None None None 60683513 Common - hypothetical protein BF4089 12 None None None 60680960 Common - putative type I restriction enzyme BF1457 139 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 60681768 Common - hypothetical protein BF2290 8 None None None 60683396 Pathogen - hypothetical protein BF3961 2 None None None 60680676 Common - hypothetical protein BF1150 3 None None None 60681417 Common - putative RumB/ImpB like DNA repair protein BF1928 183 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 60680862 Common - putative transmembrane Na+/H+ antiporter BF1346 62 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 60680917 Common - putative dioxygenase BF1405 135 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 60679914 Common - putative transmembrane protein BF0325 57 COG3174 COG3174, Predicted membrane protein Function unknown 60680996 Pathogen - putative transmembrane protein BF1494 1 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 60681001 Common - hypothetical protein BF1499 4 None None None 60683210 Pathogen - hypothetical protein BF3765 2 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 60681434 Common - recombination factor protein RarA BF1945 240 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 60680040 Common - putative phage-derived protein BF0467 8 None None None 60680150 Pathogen - hypothetical protein BF0584 4 None None None 60682330 Common - putative hydrolase BF2860 101 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 60681593 Common - putative RNA-directed DNA polymerase from retron BF2112 42 None None None 60683283 Pathogen - hypothetical protein BF3840 3 None None None 60682945 Common - putative anaerobic ribonucleoside-triphosphate reductase activating protein BF3485 74 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 60680325 Common manA putative mannosidase BF0771 18 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 60682602 Common - hypothetical protein BF3133 29 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 60679614 Common - conserved hypothetical iron transport-related transmembrane protein BF0017 14 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 60681015 Common - putative anti-sigma factor BF1513 33 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60680617 Pathogen - hypothetical protein BF1081 1 None None None 60680145 Pathogen - conserved hypothetical lipoprotein BF0577 1 None None None 60680227 Common - putative histidine kinase BF0668 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60681853 Common - hypothetical protein BF2373 7 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 60681137 Pathogen - hypothetical protein BF1643 1 COG4907 COG4907, Predicted membrane protein Function unknown 60680565 Common wcfH putative deacetylase BF1022 15 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 60681035 Common tnpA putative transposase for insertion sequence element IS21-like BF1534 54 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 60681697 Common pyrD2 dihydroorotate dehydrogenase 2 BF2218 158 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 60683470 Pathogen - hypothetical protein BF4036 2 None None None 60681666 Pathogen - hypothetical protein BF2187 2 None None None 60680669 Common - hypothetical protein BF1143 18 COG4864 COG4864, Uncharacterized protein conserved in bacteria Function unknown 60683183 Common - putative tansport related protein BF3738 34 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 60682901 Common - hypothetical protein BF3440 7 COG2319 COG2319, FOG: WD40 repeat General function prediction only 60680305 Common - putative acetyltransferase BF0750 204 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 60681551 Common nqrC Na(+)-translocating NADH-quinone reductase subunit C BF2067 47 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 60679807 Common fucO L-1,2-propanediol oxidoreductase BF0212 176 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 60683553 Common - putative outer membrane protein BF4132 13 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680590 Common - putative 3,4-dihydroxy-2-butanone 4-phosphate/shikimate 5-dehydrogenase fusion protein BF1051 237 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 60682351 Pathogen - hypothetical protein BF2881 1 None None None 60683604 Common - putative aldose 1-epimerase precursor BF4183 100 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 60683662 Common pckA phosphoenolpyruvate carboxykinase BF4244 96 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 60682979 Pathogen - hypothetical protein BF3521 1 None None None 60682969 Common - putative metal resistance related exported protein BF3511 152 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60683748 Common - putative transmembrane PAP2-family protein BF4336 2 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 60679870 Common - hypothetical protein BF0277 20 COG3940 COG3940, Predicted beta-xylosidase General function prediction only 60681513 Common - hypothetical protein BF2025 2 None None None 60681804 Pathogen - hypothetical protein BF2326 1 None None None 60679843 Common ftsZ cell division protein FtsZ BF0250 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 60679749 Common - UDP-N-acetylglucosamine acyltransferase BF0153 179 COG1043 LpxA, Acyl- acyl carrier protein 60679842 Common - hypothetical protein BF0249 149 COG1610 COG1610, Uncharacterized conserved protein Function unknown 60680621 Pathogen - hypothetical protein BF1089 1 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 60680700 Common - putative transmembrane protein BF1175 118 COG2855 COG2855, Predicted membrane protein Function unknown 60681494 Common - hypothetical protein BF2006 2 COG3520 COG3520, Uncharacterized protein conserved in bacteria Function unknown 60682096 Common rnfD electron transport complex protein RnfD BF2617 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 60682588 Pathogen - putative lipoprotein BF3119 1 None None None 60682944 Common - anaerobic ribonucleoside triphosphate reductase BF3484 105 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 60681986 Common hup2 putative histone-like DNA-binding protein HU2 BF2506 9 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60682912 Common - putative LPS biosynthesis related conserved hypothetical protein BF3451 13 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 60679766 Pathogen - hypothetical protein BF0171 1 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 60680032 Common pyrE orotate phosphoribosyltransferase BF0455 156 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 60680261 Common - putative transmembrane AAA-metalloprotease FtsH BF0702 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 60679624 Common - putative SAM/TRAM family methylase protein BF0027 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 60679675 Common tyrS putative tyrosyl-tRNA synthetase 1 BF0079 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60679788 Common - hypothetical protein BF0193 109 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 60680167 Common fumB putative fumarate hydratase class I, anaerobic BF0601 146 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 60680399 Common - putative transmembrane protein BF0848 27 COG2510 COG2510, Predicted membrane protein Function unknown 60680430 Common - putative histidinol-phosphatase BF0879 30 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 60681149 Pathogen - hypothetical protein BF1655 1 None None None 60682712 Common purA adenylosuccinate synthetase BF3243 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 60682363 Common - hypothetical protein BF2893 79 COG3586 COG3586, Uncharacterized conserved protein Function unknown 60683361 Common - hypothetical protein BF3924 6 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 60683613 Pathogen - hypothetical protein BF4192 2 COG4092 COG4092, Predicted glycosyltransferase involved in capsule biosynthesis Cell envelope biogenesis, outer membrane 60680509 Pathogen - hypothetical protein BF0962 2 None None None 60683742 Common - putative transmembrane ion channel BF4330 173 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 60682646 Common scrL levanase BF3177 53 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 60681141 Pathogen - hypothetical protein BF1647 3 None None None 60681459 Pathogen - hypothetical protein BF1971 1 None None None 60682456 Common - putative ABC transport system, membrane protein BF2986 181 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60682757 Common - hypothetical protein BF3289 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 60680936 Common cdd putative cytidine deaminase BF1427 84 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 60681860 Common - putative metallo-beta-lactamase superfamily protein BF2380 73 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 60682170 Common - putative exported TonB-dependent receptor protein BF2697 116 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60681008 Pathogen - hypothetical protein BF1506 1 None None None 60680651 Common - putative restriction enzyme of type III restriction-modification system BF1122 42 COG3587 COG3587, Restriction endonuclease Defense mechanisms 60680274 Pathogen - hypothetical protein BF0715 1 None None None 60683308 Common - hypothetical protein BF3866 184 COG1475 Spo0J, Predicted transcriptional regulators Transcription 60683351 Common - putative transmembrane protein BF3914 6 None None None 60680501 Common - putative beta-N-acetylhexosaminidase BF0953 56 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60682795 Pathogen - putative lipoprotein BF3327 2 None None None 60681516 Common - putative aminotransferase BF2028 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 60683040 Common - hypothetical protein BF3589 11 None None None 60681616 Common - putative AraC family transcriptional regulatory protein BF2137 114 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60681278 Pathogen - hypothetical protein BF1786 1 None None None 60681755 Common - putative penicillin-binding peptidoglycan biosynthesis-related exported protein BF2276 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 60680489 Common - putative ATP-binding component of ABC transporter BF0940 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 60683271 Pathogen - hypothetical protein BF3828 2 COG4092 COG4092, Predicted glycosyltransferase involved in capsule biosynthesis Cell envelope biogenesis, outer membrane 60682099 Pathogen - hypothetical protein BF2620 3 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 60683446 Common - putative transmembrane protein, transglycosylase associated BF4011 7 None None None 60680345 Common nuoB NADH-quinone oxidoreductase chain B BF0791 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 60682846 Common - putative xanthine/uracyl permease, membrane protein BF3384 126 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 60679907 Common - putative exported rhamnosidase protein BF0318 25 None None None 60682619 Common - putative conserved lipoprotein BF3150 157 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60683460 Common rpsU 30S ribosomal protein S21 BF4025 5 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 60682369 Common - hypothetical protein BF2899 33 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 60680205 Common - putative transmembrane protein BF0644 7 COG1714 COG1714, Predicted membrane protein/domain Function unknown 60681354 Pathogen - hypothetical protein BF1863 1 None None None 60681687 Common - hypothetical protein BF2208 4 None None None 60680355 Common - possible alpha-galactosidase BF0803 4 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 60680733 Common ahpC alkyl hydroperoxide reductase C subunit BF1210 219 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60681380 Common - hypothetical protein BF1890 6 None None None 60682215 Common - putative glycogen biosynthesis-related protein BF2742 9 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60682121 Common uvrB excinuclease ABC subunit B BF2642 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 60682188 Pathogen - hypothetical protein BF2715 1 None None None 60680329 Pathogen - putative transmembrane protein BF0775 2 None None None 60683245 Common aapE putative outer membrane protein BF3800 6 None None None 60681378 Common - putative GDP mannose 4,6-dehydratase BF1888 226 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 60680343 Common nuoH putative NADH dehydrogenase subunit H BF0789 187 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 60682151 Common trpC indole-3-glycerol phosphate synthase BF2676 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 60683105 Common - putative glutathione peroxidase BF3656 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 60682561 Common - hypothetical protein BF3092 14 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 60680065 Common - putative bioynthetic peptidoglycan transglycosylase BF0495 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 60681154 Common tktB putative transketolase BF1660 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 60682324 Common recN DNA repair protein BF2854 198 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 60680402 Common - putative beta-galactosidase BF0851 71 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60683770 Common - putative RNA polymerase ECF-type sigma factor BF4359 96 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60682875 Common - hypothetical protein BF3413 5 None None None 60683681 Common sahH S-adenosyl-L-homocysteine hydrolase BF4263 177 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 60679999 Pathogen - hypothetical protein BF0420 1 None None None 60682054 Common - hypothetical protein BF2575 3 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 60679775 Common purN putative phosphoribosylglycinamide formyltransferase BF0180 221 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 60683756 Common - putative AraC-family transcriptional regulator BF4345 26 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60682545 Pathogen - hypothetical protein BF3076 1 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 60683480 Common - putative transposase BF4052 50 COG3666 COG3666, Transposase and inactivated derivatives DNA replication, recombination, and repair 60683004 Common - putative reductoisomerase BF3546 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 60683475 Common - putative transposase BF4041 73 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 60680886 Pathogen wzy3 putative LPS biosynthesis related integral membrane protein BF1372 1 None None None 60681064 Common - putative lipopolysaccharide biosynthesis glycosyltransferase BF1563 96 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 60681852 Common - putative tRNA/rRNA methyltransferase BF2372 116 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 60683487 Common - putative beta-hexosaminidase precursor BF4059 54 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60683692 Common pyk pyruvate kinase BF4277 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 60681706 Common atpD F0F1 ATP synthase subunit beta BF2227 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 60683047 Common - putative cation transport related membrane protein BF3596 153 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60682464 Pathogen - hypothetical protein BF2994 1 None None None 60683426 Common rplE 50S ribosomal protein L5 BF3991 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 60682373 Common - putative dimethylamine corrinoid protein BF2903 168 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 60679800 Pathogen - putative transmembrane protein BF0205 1 COG3710 CadC, DNA-binding winged-HTH domains Transcription 60680039 Common - putative TonB-dependent receptor BF0466 6 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 60682568 Common - putative sigma factor BF3099 98 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60680209 Common - hypothetical protein BF0650 4 None None None 60683148 Common - hypothetical protein BF3702 6 None None None 60683699 Pathogen - hypothetical protein BF4284 2 None None None 60683277 Pathogen - putative lipoprotein BF3834 2 None None None 60683443 Common - hypothetical protein BF4008 13 None None None 60681389 Common aepZ putative LPS biosynthesis related 2-aminoethylphosphonate pyruvate aminotransferase BF1899 179 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 60681913 Common - hypothetical protein BF2434 14 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 60679790 Common - hypothetical protein BF0195 8 None None None 60680891 Common wcfS undecaprenyl-phosphate galactose phosphotransferase BF1377 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 60681940 Pathogen - hypothetical protein BF2460 1 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60683611 Pathogen - hypothetical protein BF4190 2 None None None 60683623 Pathogen - hypothetical protein BF4203 2 None None None 60680502 Common - putative FNR-family transcriptional regulator protein BF0954 124 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 60681487 Pathogen - hypothetical protein BF1999 1 None None None 60681760 Common - putative two component system response regulator BF2282 53 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 60681423 Common - putative ABC transporter ATP-binding component BF1934 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 60683725 Common - putative two-component system sensor, no kinase domain BF4313 96 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 60681308 Common - putative outer membrane protein BF1816 11 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680983 Pathogen - hypothetical protein BF1481 3 None None None 60683191 Common - hypothetical protein BF3745 19 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60683532 Common - hypothetical protein BF4108 26 COG3506 COG3506, Uncharacterized conserved protein Function unknown 60680555 Common rmlC1 dTDP-6-deoxy-D-glucose-3,5 epimerase BF1012 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 60683065 Common - putative exported N-acetylmuramoyl-L-alanine amidase BF3615 173 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 60682538 Pathogen - hypothetical protein BF3069 1 None None None 60682136 Common - putative phosphoribosylpyrophosphate amidotransferase BF2659 231 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 60680280 Common - putative AraC-family regulatory protein BF0723 134 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60682106 Common - putative exported aminopeptidase BF2627 173 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 60681907 Pathogen - hypothetical protein BF2428 1 None None None 60683781 Pathogen - hypothetical protein BF4370 1 None None None 60681376 Common - hypothetical protein BF1886 217 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 60680010 Common rpmH 50S ribosomal protein L34 BF0432 196 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 60682535 Pathogen - hypothetical protein BF3066 2 None None None 60680368 Common - putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase BF0816 208 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 60680742 Common - putative transposase BF1219 98 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60681677 Common - hypothetical protein BF2198 60 COG0714 COG0714, MoxR-like ATPases General function prediction only 60682893 Common - hypothetical protein BF3431 3 None None None 60682779 Common - hypothetical protein BF3311 42 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 60680607 Common - hypothetical protein BF1070 27 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 60681216 Pathogen - hypothetical protein BF1724 1 None None None 60681746 Pathogen - hypothetical protein BF2267 2 None None None 60679948 Common - putative NapC/NirT cytochrome c-type protein BF0360 37 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 60681290 Common - putative outer membrane protein BF1798 25 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60679742 Common - possible signal peptidase BF0146 120 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 60680980 Pathogen - hypothetical protein BF1478 1 None None None 60682442 Pathogen - hypothetical protein BF2972 1 None None None 60683684 Common - putative arylsulfatase BF4266 89 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60683011 Common - hypothetical protein BF3553 4 None None None 60680369 Common - hypothetical protein BF0817 12 None None None 60683209 Common - putative acylhydrolase BF3764 23 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 60680781 Common bexA putative transmembrane MatE family multidrug efflux transporter BF1262 114 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60680061 Common - hypothetical protein BF0491 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 60681125 Pathogen - hypothetical protein BF1629 1 None None None 60679975 Common - putative transmembrane protein BF0390 8 COG5652 COG5652, Predicted integral membrane protein Function unknown 60683643 Common - hypothetical protein BF4223 8 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 60680422 Common - hypothetical protein BF0871 18 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60681180 Pathogen - hypothetical protein BF1686 2 None None None 60680658 Pathogen - hypothetical protein BF1129 1 None None None 60681582 Pathogen - hypothetical protein BF2100 2 None None None 60682781 Common - putative AraC-family regulatory protein BF3313 103 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 60683582 Common - putative transmembrane protein BF4161 10 None None None 60679833 Common - putative cationic transporter BF0240 104 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 60680514 Common - putative two-component sensor histidine kinase BF0967 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60683576 Common - hypothetical protein BF4154 36 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 60682182 Common - putative cobalamin biosynthesis-related protein BF2709 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 60682205 Pathogen - hypothetical protein BF2732 1 None None None 60682118 Common - conserved hypothetical lipoprotein BF2639 35 COG4105 ComL, DNA uptake lipoprotein General function prediction only 60682160 Common - putative DNA-binding response regulator BF2686 126 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 60683157 Common - hypothetical protein BF3712 11 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60682289 Pathogen - hypothetical protein BF2818 1 None None None 60679945 Pathogen - hypothetical protein BF0357 1 None None None 60679951 Common - putative cytochrome c biogenesis protein BF0363 107 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 60681782 Pathogen - hypothetical protein BF2304 1 None None None 60682409 Common - putative lipoprotein BF2939 6 None None None 60681301 Common estS sialate O-acetylesterase BF1809 16 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 60683242 Pathogen aapH hypothetical protein BF3797 1 None None None 60680189 Common - putative uridylate kinase BF0626 235 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 60681314 Pathogen - putative transmembrane protein BF1822 1 None None None 60682895 Pathogen - hypothetical protein BF3433 2 None None None 60681167 Common - putative sulfite synthesis pathway protein BF1673 171 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 60681343 Pathogen - possible ATP/GTP-binding chaperonin BF1852 2 None None None 60680845 Pathogen - hypothetical protein BF1327 2 None None None 60681187 Common - putative exported Tpr repeat-family protein BF1693 114 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 60682671 Common - putative electron transfer flavoprotein beta-subunit BF3202 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 60683260 Common - putative fucosyltransferase BF3816 6 None None None 60680007 Common radC1 putative DNA repair protein BF0428 176 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 60680239 Common - conserved hypothetical lipoprotein BF0680 5 None None None 60682035 Common - putative helicase BF2555 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 60680050 Common - putative regulatory protein BF0477 79 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 60681194 Common paaK2 putative phenylacetate-coenzyme A ligase BF1700 130 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 60680217 Common - hypothetical protein BF0658 3 None None None 60683083 Common - putative MarR-family regulatory protein BF3633 118 COG1846 MarR, Transcriptional regulators Transcription 60682520 Common - hypothetical protein BF3050 2 COG2149 COG2149, Predicted membrane protein Function unknown 60680662 Common int putative bacteriophage integrase BF1136 152 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60683094 Pathogen - putative lipoprotein BF3643 2 None None None 60682146 Common - putative alcohol dehydrogenase BF2670 164 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 60681531 Common - putative transmembrane endonuclease/exonuclease/phosphatase family protein BF2046 11 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 60682737 Common leuA putative 2-isopropylmalate synthase 1 BF3267 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 60681891 Pathogen - hypothetical protein BF2412 1 None None None 60680442 Common - hypothetical protein BF0892 4 None None None 60680829 Common - hypothetical protein BF1311 5 None None None 60681037 Pathogen - hypothetical protein BF1536 1 None None None 60683595 Common - hypothetical protein BF4174 30 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 60683768 Common - putative exoribonuclease BF4357 192 COG0557 VacB, Exoribonuclease R Transcription 60681450 Common - putative transmembrane transporter BF1961 188 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 60679687 Common - putative metal uptake system ABC transporter ATP-binding protein BF0091 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 60681797 Pathogen - hypothetical protein BF2319 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60682740 Pathogen - hypothetical protein BF3270 1 None None None 60682958 Common gmk guanylate kinase BF3500 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 60681725 Common - putative exported periplasmic protein BF2246 22 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 60681937 Common - hypothetical protein BF2457 14 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60683500 Common - hypothetical protein BF4076 4 None None None 60680524 Common - putative outer membrane protein BF0978 6 None None None 60683654 Common - putative AraC-family transcriptional regulatory protein BF4234 22 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60679733 Common - putative sugar isomerase SIS-domain protein BF0137 153 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 60682886 Pathogen - putative lipoprotein BF3424 1 None None None 60682241 Common pstB phosphate import ATP-binding protein BF2769 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 60681590 Common - putative transcriptional regulator BF2109 130 COG1678 COG1678, Putative transcriptional regulator Transcription 60683505 Common - hypothetical protein BF4081 9 None None None 60682960 Common - putative phosphoesterase BF3502 100 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 60680712 Common - putative polysialic acid transport protein BF1187 91 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 60680727 Common - putative outer membrane protein BF1204 20 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680333 Common - hypothetical protein BF0779 24 None None None 60682111 Common - putative transport-related membrane protein BF2632 82 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 60682243 Common - putative phosphate-related ABC transport system, membrane protein BF2771 236 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 60682553 Common - putative exported beta-galactosidase BF3084 74 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60679637 Pathogen - hypothetical protein BF0040 1 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 60681545 Common - putative transmembrane protein BF2061 15 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 60680136 Common - putative RNA polymerase ECF-type sigma factor BF0568 86 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60682352 Pathogen - hypothetical protein BF2882 1 None None None 60681160 Pathogen - putative transmembrane protein BF1666 1 None None None 60680174 Common - putative HlyD-family transporter BF0609 63 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 60682043 Common - putative molybdopterin biosynthesis-related protein BF2563 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 60682406 Common - putative hydrolase BF2936 43 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 60680871 Pathogen - hypothetical protein BF1355 1 None None None 60680808 Common gcvT glycine cleavage system aminomethyltransferase T BF1290 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 60682726 Pathogen - hypothetical protein BF3256 1 None None None 60681784 Pathogen - hypothetical protein BF2306 1 None None None 60681992 Common - putative glycoprotease BF2512 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 60680472 Common - possible glycogen synthase BF0923 51 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 60681483 Pathogen - hypothetical protein BF1995 1 None None None 60679729 Pathogen - hypothetical protein BF0133 1 None None None 60680128 Common thrC threonine synthase BF0560 196 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 60682579 Common - hypothetical protein BF3110 46 COG2311 COG2311, Predicted membrane protein Function unknown 60682902 Pathogen - hypothetical protein BF3441 1 None None None 60680903 Common ldhA D-lactate dehydrogenase BF1389 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 60679799 Pathogen - putative transmembrane protein BF0204 1 None None None 60683651 Pathogen - hypothetical protein BF4231 1 None None None 60680735 Pathogen - hypothetical protein BF1212 1 None None None 60683289 Pathogen - hypothetical protein BF3846 1 None None None 60683400 Common - putative TetR transcriptional regulator BF3965 53 COG1309 AcrR, Transcriptional regulator Transcription 60683715 Common - putative UDP-N-acetylglucosamine 2-epimerase BF4303 155 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 60680059 Common - putative ion transport protein BF0488 30 None None None 60683196 Common - hypothetical protein BF3750 9 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 60681325 Common - putative bacteriophage integrase BF1833 65 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60679751 Common - putative AcrB/AcrD family RND transport protein BF0155 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60682270 Pathogen - possible glycosyltransferase BF2799 1 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60682612 Common - conserved hypothetical lipoprotein BF3143 178 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 60682990 Pathogen - hypothetical protein BF3532 1 None None None 60680698 Pathogen - hypothetical protein BF1173 1 None None None 60683166 Common - putative exported sulfatase BF3721 88 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60681102 Common - putative two-component response regulator transcriptional regulatory protein BF1606 208 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 60682543 Common - hypothetical protein BF3074 31 COG4704 COG4704, Uncharacterized protein conserved in bacteria Function unknown 60683362 Common - putative two-component system sensor histidine kinase/response regulator fusion protein BF3925 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60680783 Common - hypothetical protein BF1264 3 None None None 60680374 Common - putative transmembrane protein BF0823 160 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 60683594 Common - putative PfkB family carbohydrate kinase BF4173 201 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 60679950 Common - putative transmembrane protein BF0362 7 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 60681401 Common wcgU putative LPS biosynthesis related reductase BF1911 131 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 60683301 Common aspC2 putative aspartate aminotransferase BF3859 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 60679760 Common - putative two-component regulatory system, sensor kinase protein BF0165 220 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 60681106 Common - putative ABC transport system ATP-binding protein BF1610 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 60682650 Pathogen - putative lipoprotein BF3181 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60682571 Common - hypothetical protein BF3102 5 None None None 60683385 Pathogen - hypothetical protein BF3948 1 None None None 60681971 Common htpG heat shock protein 90 BF2491 148 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 60682194 Common - putative aceyltransferase BF2721 23 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 60682894 Common - hypothetical protein BF3432 3 None None None 60681299 Common nahA beta-N-acetylhexoosaminidase BF1807 49 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60682134 Common carB1 putative carbamoyl-phosphate synthase large chain 1 BF2657 232 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 60682492 Common nadE NAD synthetase BF3022 199 COG0171 NadE, NAD synthase Coenzyme metabolism 60683005 Common - hypothetical protein BF3547 6 None None None 60681422 Common - putative permease component of ABC transporter BF1933 212 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60683589 Common - putative outer membrane protein BF4168 6 None None None 60681476 Common - putative outer membrane protein BF1988 121 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60680792 Pathogen - hypothetical protein BF1273 1 None None None 60682992 Common - conserved hypothetical outer membrane protein BF3534 18 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 60683032 Common - hypothetical protein BF3579 7 None None None 60683293 Common - hypothetical protein BF3851 171 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60683580 Common - putative aminopeptidase BF4158 176 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 60680744 Common radC2 putative DNA repair protein BF1221 154 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 60679900 Pathogen - hypothetical protein BF0311 1 None None None 60680456 Common - putative Sua5/yciO/yrdC family protein BF0907 184 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 60681203 Common - putative LPS-related regulatory protein BF1709 23 COG0250 NusG, Transcription antiterminator Transcription 60681999 Common - putative phosphoribosyltransferase BF2519 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 60683583 Common - glycine cleavage system protein H BF4162 188 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 60682866 Common - putative copper homeostasis protein BF3404 58 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 60683501 Common - hypothetical protein BF4077 16 None None None 60683369 Common fabG putative 3-oxoacyl-[acyl-carrier protein] reductase BF3932 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 60682471 Pathogen - hypothetical protein BF3001 1 None None None 60682023 Common - putative cobalamin biosynthesis-related membrane protein BF2543 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 60682217 Common - putative V(vacuolar)-type Na+ ATP synthase subunit I BF2744 41 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 60681282 Common - putative ferredoxin BF1790 15 COG1145 NapF, Ferredoxin Energy production and conversion 60681785 Pathogen - hypothetical protein BF2307 1 None None None 60681569 Common - possible exported heavy-metal binding protein BF2085 6 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 60682454 Common - putative ABC transport system, membrane protein BF2984 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60680410 Common - putative AraC transcriptional regulatory protein BF0859 124 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 60682234 Common - putative lipoprotein BF2762 67 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 60682783 Pathogen - hypothetical protein BF3315 1 None None None 60682930 Pathogen - hypothetical protein BF3470 1 None None None 60682951 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase BF3492 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 60681352 Pathogen - hypothetical protein BF1861 1 None None None 60681036 Common tnpB insertion sequence IS21-like putative ATP-binding protein BF1535 92 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 60680259 Pathogen - hypothetical protein BF0700 2 None None None 60681244 Pathogen - hypothetical protein BF1752 3 None None None 60682300 Pathogen - hypothetical protein BF2829 1 None None None 60682869 Common - hypothetical protein BF3407 5 None None None 60683320 Pathogen ubb putative ubiquitin BF3883 2 COG5272 UBI4, Ubiquitin Posttranslational modification, protein turnover, chaperones 60681024 Pathogen - hypothetical protein BF1523 1 None None None 60682688 Common - hypothetical protein BF3219 2 None None None 60682210 Common - putative ABC transport system, membrane protein BF2737 170 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 60681607 Common - putative flavoredoxin BF2126 27 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 60681510 Common - hypothetical protein BF2022 2 None None None 60680115 Common - putative exported rhamnosidase A BF0546 23 None None None 60682657 Common - putative lipoprotein BF3188 4 None None None 60683621 Common - putative glycosyl transferase BF4200 204 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60681220 Common - hypothetical protein BF1728 3 None None None 60683204 Common - putative outer membrane protein BF3759 104 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60682239 Common ribE riboflavin synthase subunit alpha BF2767 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 60682597 Common mmdA putative methylmalonyl-CoA decarboxylase, alpha-subunit BF3128 210 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 60680678 Common - putative transmembrane glycosyltransferase BF1152 205 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60681097 Common - aspartate aminotransferase BF1601 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 60679897 Common - hypothetical protein BF0307 2 None None None 60681452 Common - possible anti-sigma factor BF1963 29 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60682314 Common - putative regulatory protein BF2844 210 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 60680255 Common parA putative ParA chromosome partitioning protein BF0696 232 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 60680169 Common - putative alpha-N-acetylglucosaminidase BF0603 7 None None None 60683763 Common - hypothetical protein BF4352 12 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 60679772 Common - putative ribonuclease III BF0177 215 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 60680682 Common crcB putative transmembrane camphor resistance and chromosome condensation CrcB homologue BF1157 173 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 60682762 Pathogen - hypothetical protein BF3294 1 None None None 60679851 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase BF0258 211 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 60679925 Common - putative two-component sensor histidine kinase BF0336 25 COG3292 COG3292, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 60680106 Common frrH putative outer membrane protein BF0537 5 None None None 60683174 Common tpiA triosephosphate isomerase BF3729 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 60682609 Common rpmE2 50S ribosomal protein L31 type B BF3140 146 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 60681600 Common - hypothetical protein BF2119 3 None None None 60681140 Pathogen - hypothetical protein BF1646 3 None None None 60680763 Common - conserved hypothetical transmembrane protein found in conjugate transposon BF1243 3 None None None 60680546 Common - putative transmembrane transporter BF1002 40 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 60680533 Common - putative outer membrane protein BF0990 7 None None None 60683638 Pathogen - hypothetical protein BF4218 1 None None None 60682444 Common - hypothetical protein BF2974 8 COG4430 COG4430, Uncharacterized protein conserved in bacteria Function unknown 60680925 Common - putative outer membrane protein BF1415 24 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680945 Common - putative ABC transporter permease component BF1436 30 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60681336 Common - putative integrase/transposase BF1845 11 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60681957 Common - putative drug resistance transport-related membrane protein BF2477 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60681468 Pathogen - hypothetical protein BF1980 1 None None None 60683442 Common rpsL 30S ribosomal protein S12 BF4007 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 60682614 Common - hypothetical protein BF3145 6 None None None 60680675 Common - putative transmembrane protein BF1149 65 COG1971 COG1971, Predicted membrane protein Function unknown 60680774 Common exc putative transposon excision protein BF1254 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 60682417 Common - putative acriflavine resistance protein E precursor BF2947 159 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60680324 Common - putative methylcobamide:CoM methyltransferase BF0770 74 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 60682435 Common - dihydroorotase BF2965 209 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 60682097 Common rnfC electron transport complex protein BF2618 88 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 60681406 Pathogen - hypothetical protein BF1917 3 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60682346 Pathogen - hypothetical protein BF2876 1 COG1959 COG1959, Predicted transcriptional regulator Transcription 60679664 Common - putative undecaprenol kinase BF0068 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 60680876 Common - hypothetical protein BF1360 2 None None None 60683029 Common - putative RNA polymerase sigma factor BF3574 90 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60679822 Common - hypothetical protein BF0228 5 None None None 60683735 Common - putative TonB-dependent outer membrane receptor protein BF4323 13 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60680542 Common - putative sigma-54 dependent transcriptional regulator BF0998 168 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 60682872 Common - putative RNA polymerase sigma factor BF3410 87 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60680710 Common - putative iron transport-related family system permease protein BF1185 189 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 60683233 Pathogen - hypothetical protein BF3788 1 None None None 60681776 Pathogen - hypothetical protein BF2298 1 None None None 60683345 Common - putative 5,10-methylenetetrahydrofolate reductase BF3908 150 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 60680795 Common - putative zinc-binding alcohol dehydrogenase BF1277 199 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 60683071 Common - putative acetyltransferase membrane protein BF3621 33 COG3594 NolL, Fucose 4-O-acetylase and related acetyltransferases Carbohydrate transport and metabolism 60682734 Common - putative alpha-isopropylmalate synthase 2 BF3264 206 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 60679724 Common ruvB Holliday junction DNA helicase B BF0128 238 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 60680988 Pathogen - putative transmembrane protein BF1486 1 None None None 60679996 Common - hypothetical protein BF0416 24 COG4866 COG4866, Uncharacterized conserved protein Function unknown 60682703 Common - hypothetical protein BF3234 25 COG0392 COG0392, Predicted integral membrane protein Function unknown 60680757 Common - conserved hypothetical protein found in conjugate transposon BF1237 5 None None None 60682201 Common - putative cation antiporter BF2728 71 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 60682980 Common - putative phospholipid biosynthesis related protein BF3522 153 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 60679753 Common - putative exported beta-galactosidase BF0157 72 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60683018 Common - hypothetical protein BF3560 35 COG3681 COG3681, Uncharacterized conserved protein Function unknown 60683670 Common - putative transmembrane protein BF4252 18 COG4299 COG4299, Uncharacterized protein conserved in bacteria Function unknown 60683493 Common - hypothetical protein BF4065 2 COG3391 COG3391, Uncharacterized conserved protein Function unknown 60683495 Pathogen - hypothetical protein BF4070 1 None None None 60680086 Common - putative hydrolase/beta lactamase fusion protein BF0517 199 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 60679892 Common - putative transmembrane protein BF0301 49 COG2311 COG2311, Predicted membrane protein Function unknown 60681277 Common - putative DNA primase BF1785 47 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 60682069 Common pheT phenylalanyl-tRNA synthetase subunit beta BF2590 244 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 60681731 Common - putative two component system response regulator BF2252 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 60680610 Common - putative DNA-binding protein BF1073 21 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 60681000 Pathogen - putative DNA-binding protein BF1498 1 COG2378 COG2378, Predicted transcriptional regulator Transcription 60681056 Common - putative dNTP-hexose dehydratase-epimerase BF1555 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60682924 Common - putative LPS biosynthesis related polysaccharide transporter BF3463 61 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 60683022 Common - hypothetical protein BF3567 4 None None None 60681615 Common - short chain dehydrogenase BF2136 220 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 60680140 Common - putative outer membrane protein BF0572 5 None None None 60682401 Common - putative oxidoreductase BF2931 202 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 60680076 Common - putative outer membrane transport/efflux protein BF0506 123 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60683251 Common - hypothetical protein BF3807 64 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 60682008 Common - putative outer membrane protein BF2528 57 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60681635 Pathogen - hypothetical protein BF2156 1 None None None 60681428 Common - hypothetical protein BF1939 23 COG3831 COG3831, Uncharacterized conserved protein Function unknown 60679886 Common - putative exported glycosylhydrolase BF0295 5 COG4833 COG4833, Predicted glycosyl hydrolase Carbohydrate transport and metabolism 60683138 Common - possible flippase BF3692 11 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 60680121 Common - putative LuxR family transcriptional regulator BF0552 100 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 60679862 Common - hypothetical protein BF0269 38 COG3176 COG3176, Putative hemolysin General function prediction only 60682044 Common - putative thiamine phosphate pyrophosphorylase BF2564 10 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 60679686 Pathogen - hypothetical protein BF0090 3 None None None 60682483 Common - hypothetical protein BF3013 19 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 60681412 Pathogen - hypothetical protein BF1923 2 None None None 60682816 Common - putative cysteine biosynthesis related protein BF3351 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 60679636 Pathogen - hypothetical protein BF0039 1 None None None 60680000 Pathogen - hypothetical protein BF0421 1 None None None 60681092 Common - putative ATP-binding component of ABC transporter BF1596 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 60681360 Pathogen - hypothetical protein BF1869 1 None None None 60681002 Pathogen - hypothetical protein BF1500 1 None None None 60682603 Common - putative alpha-amylase precursor BF3134 176 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 60680918 Common ald putative alanine dehydrogenase BF1406 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 60683122 Common fmt methionyl-tRNA formyltransferase BF3673 220 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 60683335 Common - putative ABC transport system, ATP-binding protein BF3898 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 60681241 Common - hypothetical protein BF1749 3 None None None 60683104 Common - putative NUDIX domain conserved hypothetical protein BF3655 50 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 60680310 Pathogen - hypothetical protein BF0755 1 None None None 60680854 Pathogen - hypothetical protein BF1337 1 None None None 60681138 Common - hypothetical protein BF1644 6 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 60680587 Pathogen - hypothetical protein BF1048 1 None None None 60680999 Pathogen - hypothetical protein BF1497 1 None None None 60680648 Common - hypothetical protein BF1119 14 None None None 60682259 Pathogen - hypothetical protein BF2788 1 None None None 60680228 Common - putative glycosyl hydrolase, beta-N-acetylhexosaminidase BF0669 54 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60680618 Pathogen - hypothetical protein BF1082 1 None None None 60682336 Pathogen - putative lipoprotein BF2866 1 None None None 60683415 Common rpmJ 50S ribosomal protein L36 BF3980 51 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 60681115 Common - hypothetical protein BF1619 6 None None None 60680863 Common - putative transmembrane protein BF1347 38 COG1814 COG1814, Uncharacterized membrane protein Function unknown 60683512 Common tsr26 tyrosine site-specific recombinase BF4088 6 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60683775 Common - putative metalloprotease BF4364 3 None None None 60682476 Pathogen - hypothetical protein BF3006 1 None None None 60681143 Common - putative RNA polymerase ECF-type sigma factor BF1649 39 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60680972 Pathogen - putative transmembrane protein BF1469 1 None None None 60680562 Common wcfE putative glycosyltransferase BF1019 95 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 60682756 Pathogen - hypothetical protein BF3288 1 None None None 60681668 Common - putative NAD dependent epimerase/dehydratase BF2189 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60682697 Pathogen - putative lipoprotein BF3228 1 None None None 60683555 Pathogen - hypothetical protein BF4134 1 None None None 60682514 Common - hypothetical protein BF3044 4 None None None 60683704 Common - putative CoA-binding protein BF4289 144 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 60680483 Common - putative transmembrane protein BF0934 5 None None None 60680041 Pathogen - hypothetical protein BF0468 1 None None None 60681084 Common - hypothetical protein BF1587 4 None None None 60680491 Common - hypothetical protein BF0942 196 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 60680246 Common - putative efflux transporter bicyclomycin resistance protein BF0687 188 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60681838 Common - putative phosphodiesterase-nucleotide pyrophosphatase BF2358 30 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 60680103 Common rpoE putative RNA polymerase ECF sigma factor BF0534 139 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60682828 Common - putative two-component system, sensor kinase BF3364 7 None None None 60681662 Pathogen - hypothetical protein BF2183 3 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60683690 Pathogen - putative transmembrane protein BF4275 1 None None None 60681873 Common lon ATP-dependent protease BF2393 206 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 60680285 Pathogen - hypothetical protein BF0729 1 None None None 60683284 Pathogen - hypothetical protein BF3841 4 None None None 60683199 Common mdh putative malate dehydrogenase BF3753 196 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 60681807 Pathogen - hypothetical protein BF2329 1 None None None 60681066 Common - putative glycosyltransferase BF1565 125 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 60683266 Pathogen - hypothetical protein BF3823 1 None None None 60681723 Common - putative hydrolase lipoprotein BF2244 22 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 60681885 Common - hypothetical protein BF2406 4 None None None 60683031 Common - hypothetical protein BF3576 8 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60682821 Pathogen - hypothetical protein BF3356 1 None None None 60682967 Common - putative response regulator BF3509 213 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 60680560 Common wcfD putative acetyltransferase BF1017 202 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 60680817 Common - putative haloacid dehalogenase-like hydrolase BF1299 167 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 60682715 Common - hypothetical protein BF3246 7 None None None 60683675 Common - hypothetical protein BF4257 4 None None None 60680235 Common - putative methyltransferase BF0676 209 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 60683310 Pathogen - hypothetical protein BF3871 1 None None None 60683391 Pathogen - hypothetical protein BF3956 1 None None None 60680276 Common - hypothetical protein BF0717 8 None None None 60681392 Common wcfW putative LPS biosynthesis related alpha-1,2-fucosyltransferase BF1902 17 None None None 60682177 Pathogen - hypothetical protein BF2704 1 None None None 60679933 Common - hypothetical protein BF0344 10 COG4679 COG4679, Phage-related protein Function unknown 60680822 Common - putative muconate cycloisomerase BF1304 109 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 60681701 Common - putative diacylglycerol kinase BF2222 44 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 60682957 Common - hypothetical protein BF3499 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 60683740 Common - putative TonB-dependent outer membrane receptor protein BF4328 64 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680146 Common - putative TonB-dependent outer membrane receptor protein BF0578 32 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60681647 Pathogen - hypothetical protein BF2168 2 None None None 60679876 Common - putative lipoprotein BF0283 20 COG3940 COG3940, Predicted beta-xylosidase General function prediction only 60679717 Common - hypothetical protein BF0121 6 None None None 60679964 Common - putative cation symporter BF0378 78 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 60680029 Common - putative riboflavin biosynthesis protein [includes: diaminohydroxyphosphoribosylaminopyrimidine deaminase BF0452 231 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 60680084 Common - possible secreted 5'-nucleotidase BF0515 136 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 60682015 Common - hypothetical protein BF2535 3 None None None 60681949 Common - putative ABC transport system, membrane protein BF2469 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 60683327 Common - putative exported isomerase BF3890 27 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 60680899 Common pdxH putative pyridoxamine 5'-phosphate oxidase BF1385 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 60683218 Common - putative exodeoxyribonuclease VII small subunit BF3773 5 None None None 60679783 Common - putative transport ATP-binding protein BF0188 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 60681042 Pathogen - hypothetical protein BF1541 1 None None None 60680093 Common - putative MarR family transcriptional regulator BF0524 12 COG1846 MarR, Transcriptional regulators Transcription 60681562 Common - hypothetical protein BF2078 79 COG0778 NfnB, Nitroreductase Energy production and conversion 60682392 Common - hypothetical protein BF2922 57 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60682088 Common - putative DNA helicase BF2609 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 60680303 Common - putative glycosyltransferase protein BF0748 118 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60681370 Common - putative transmembrane Na+ driven efflux protein BF1879 103 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60681063 Common - putative glycosyltransferase O-antigen related protein BF1562 190 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60681610 Common - hypothetical protein BF2131 7 None None None 60679991 Pathogen - hypothetical protein BF0411 1 None None None 60680346 Common nuoA NADH-quinone oxidoreductase chain A BF0792 150 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 60681153 Common rpiB putative ribose 5-phosphate isomerase BF1659 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 60683750 Common - fumarate reductase transmembrane cytochrome b subunit BF4339 29 None None None 60680628 Common - putative ATP-binding protein BF1097 22 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 60683445 Pathogen - hypothetical protein BF4010 1 None None None 60681447 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase BF1958 198 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 60682120 Common paaK1 putative phenylacetate-coenzyme A ligase BF2641 123 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 60681407 Common - putative transmembrane symporter BF1918 156 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 60681761 Common - putative transport-related membrane protein BF2283 40 COG2978 AbgT, Putative p-aminobenzoyl-glutamate transporter Coenzyme metabolism 60680636 Pathogen - hypothetical protein BF1106 1 None None None 60680711 Common - putative iron-related ABC transport periplasmic binding protein BF1186 24 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 60681837 Common xylE D-xylose transporter XylE BF2357 122 None None None 60681168 Common - possible Na+/sulfite symporter BF1674 125 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 60680218 Common - putative alpha-1,2-mannosidase precursor BF0659 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 60680344 Common nuoC putative NADH-quinone oxidoreductase chain C/D BF0790 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 60680525 Common - putative arylsulfatase precursor BF0979 78 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60683246 Common aapD hypothetical protein BF3801 35 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60682966 Common - hypothetical protein BF3508 6 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 60683433 Common rplV 50S ribosomal protein L22 BF3998 216 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 60683272 Pathogen - hypothetical protein BF3829 2 None None None 60683350 Common mrdA putative penicillin-binding protein 2 BF3913 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 60680206 Common - putative transmembrane protein BF0647 39 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 60681355 Pathogen - hypothetical protein BF1864 1 None None None 60680777 Common - hypothetical protein BF1257 2 None None None 60681473 Common - putative transmembrane transporter protein BF1985 82 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60681049 Pathogen - hypothetical protein BF1548 1 None None None 60681309 Common - putative outer membrane protein BF1817 6 None None None 60682708 Common - hypothetical protein BF3239 2 None None None 60680038 Common - putative integrase/recombinase BF0465 23 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 60683612 Pathogen - hypothetical protein BF4191 2 None None None 60680503 Common glnA glutamine synthetase BF0955 85 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 60683211 Common - hypothetical protein BF3766 26 COG3682 COG3682, Predicted transcriptional regulator Transcription 60681912 Pathogen - hypothetical protein BF2433 2 None None None 60683048 Common - hypothetical protein BF3597 19 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 60683724 Common - putative two-component response regulator BF4312 105 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 60682569 Common - putative exported amylase BF3100 161 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 60683377 Pathogen - putative transmembrane protein BF3940 1 None None None 60679669 Common - putative lysine decarboxylase BF0073 130 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 60681418 Common - putative UmuD/RumA DNA repair protein BF1929 118 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 60679793 Common - putative extracytoplasmic function alternative sigma factor BF0198 170 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60680011 Common - putative transmembrane PASTA-domain protein BF0433 16 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 60681699 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase BF2220 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 60683278 Pathogen - hypothetical protein BF3835 1 None None None 60680661 Pathogen - putative transmembrane protein BF1134 1 None None None 60683118 Pathogen - hypothetical protein BF3669 2 None None None 60680887 Common wcfO hypothetical protein BF1373 2 None None None 60682372 Common - hypothetical protein BF2902 10 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 60682685 Pathogen - hypothetical protein BF3216 1 None None None 60683488 Common - putative beta-glucanase BF4060 34 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 60682802 Common - hypothetical protein BF3335 21 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60679710 Pathogen - putative lipoprotein BF0114 2 None None None 60682087 Common - hypothetical protein BF2608 17 COG3254 COG3254, Uncharacterized conserved protein Function unknown 60679652 Pathogen - hypothetical protein BF0056 1 None None None 60681941 Common - putative 8-amino-7-oxononanoate synthase BF2461 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 60680092 Common - hypothetical protein BF0523 7 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 60679748 Common - hypothetical protein BF0152 3 None None None 60681654 Common - hypothetical protein BF2175 11 COG4954 COG4954, Uncharacterized protein conserved in bacteria Function unknown 60679625 Common - putative alpha-L-fucosidase protein BF0028 33 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 60680026 Common - putative outer membrane protein BF0449 150 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 60679806 Common fucI L-fucose isomerase BF0211 19 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 60682269 Common - putative acetyltransferase BF2798 40 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 60683149 Common tag putative DNA-3-methyladenine glycosylase I BF3704 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 60679798 Common - hypothetical protein BF0203 55 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 60681578 Pathogen - putative transmembrane protein BF2096 2 None None None 60679615 Common - putative iron transport receptor protein BF0018 107 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 60680367 Pathogen - putative Sec-independent protein translocase component BF0815 2 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 60681665 Pathogen - hypothetical protein BF2186 2 None None None 60683605 Common - hypothetical protein BF4184 31 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 60680085 Common - possible beta-N-acetylglucosaminidase/beta-lactamase fusion protein BF0516 194 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 60683661 Common upp uracil phosphoribosyltransferase BF4243 163 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 60680884 Common wcfM putative LPS biosynthesis related UDP-galactopyranose mutase BF1370 60 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 60683554 Common - hypothetical protein BF4133 5 None None None 60682107 Common - hypothetical protein BF2628 132 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 60683010 Pathogen - hypothetical protein BF3552 2 None None None 60679674 Common - putative tatD-related DNAse protein BF0078 166 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 60682978 Common - putative RNA polymerase sigma factor BF3520 169 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60680173 Common - putative HlyD-family efflux transporter component BF0608 171 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60682060 Common - GTP-binding protein LepA BF2581 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 60680332 Pathogen - hypothetical protein BF0778 1 None None None 60680416 Common - hypothetical protein BF0865 6 None None None 60681983 Common - hypothetical protein BF2503 119 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 60681327 Common hsdR putative type I restriction enzyme R protein BF1836 148 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 60681738 Pathogen - hypothetical protein BF2259 2 None None None 60683644 Pathogen - hypothetical protein BF4224 1 None None None 60683734 Common - putative outer membrane protein BF4322 5 None None None 60680703 Common - putative RNA polymerase ECF-type sigma factor BF1178 131 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60682714 Common - hypothetical protein BF3245 52 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 60679643 Pathogen - hypothetical protein BF0046 1 None None None 60680652 Pathogen - putative ATP/GTP-binding protein BF1123 3 None None None 60680872 Common - possible cell division protein BF1356 42 COG3177 COG3177, Uncharacterized conserved protein Function unknown 60683436 Common rplW 50S ribosomal protein L23 BF4001 206 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 60681350 Pathogen - hypothetical protein BF1859 2 None None None 60681571 Common - putative AraC-type transcriptional regulator BF2087 65 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60680273 Pathogen - hypothetical protein BF0714 1 None None None 60683614 Pathogen - hypothetical protein BF4193 2 None None None 60682968 Common - putative ABC transport system, ATP-binding protein BF3510 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 60683333 Pathogen - hypothetical protein BF3896 1 None None None 60681626 Common - hypothetical protein BF2147 64 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 60683741 Common - putative acid phosphatase BF4329 17 COG1409 Icc, Predicted phosphohydrolases General function prediction only 60682307 Common - putative NRPS-secondary metabolite biosyntehsis-related protein BF2837 210 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 60683451 Common rplL 50S ribosomal protein L7/L12 BF4016 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 60683600 Common - putative two-component system sensor kinase/response regulator fusion protein BF4179 220 COG3292 COG3292, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 60682362 Pathogen - hypothetical protein BF2892 1 None None None 60680855 Common - putative esterase BF1338 91 COG0627 COG0627, Predicted esterase General function prediction only 60682587 Pathogen - hypothetical protein BF3118 1 None None None 60680622 Common - hypothetical protein BF1090 30 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 60680356 Common - hypothetical protein BF0804 20 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 60681546 Pathogen - putative outer membrane protein BF2062 2 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60679732 Common frk putative fructokinase BF0136 117 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 60682763 Common - hypothetical protein BF3295 75 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 60680697 Common clpB putative heat shock ClpB protein BF1172 220 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 60681936 Common - hypothetical protein BF2456 23 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60679789 Common - putative heat-shock protein BF0194 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 60680372 Common - hypothetical protein BF0821 11 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 60680441 Common - putative outer membrane receptor protein BF0890 45 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60683506 Common - putative vitamin B12 related Cobalamin adenosyltransferase BF4082 129 COG2096 COG2096, Uncharacterized conserved protein Function unknown 60683527 Common - putative two-component response regulator autolysis regulator LytR BF4103 116 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 60682887 Pathogen - hypothetical protein BF3425 2 None None None 60681139 Common - putative nucleotide deaminase BF1645 212 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 60683653 Pathogen - hypothetical protein BF4233 1 None None None 60682494 Common - hypothetical protein BF3024 11 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60679908 Common - putative peptidase/deacetylase BF0319 199 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 60679607 Common - hypothetical protein BF0010 57 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 60683059 Common - hypothetical protein BF3609 10 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 60680295 Pathogen - possible O-antigen related transmembrane protein BF0739 1 None None None 60682242 Common pstA phosphate transport system permease protein BF2770 227 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 60683411 Common rpoA DNA-directed RNA polymerase subunit alpha BF3976 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 60681368 Common - hypothetical protein BF1877 81 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 60680151 Common - putative tetrapyrrole (corrin/porphyrin) methylase BF0585 216 COG0313 COG0313, Predicted methyltransferases General function prediction only 60681543 Common - putative capsule-related glycosyltransferase BF2059 152 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 60681379 Common - hypothetical protein BF1889 42 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 60682005 Pathogen - conserved hypothetical DNA-binding protein BF2525 2 None None None 60681956 Common - putative transport-related protein BF2476 153 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60680421 Common - putative anti-sigma factor BF0870 36 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60680532 Common - pantothenate kinase BF0989 133 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 60681038 Common - putative type I restriction-modification specificity protein BF1537 68 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 60682276 Common - putative 4Fe-4S binding protein BF2805 9 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 60679982 Common - putative transmembrane protein BF0397 70 COG1624 COG1624, Uncharacterized conserved protein Function unknown 60682271 Pathogen - putative transmembrane protein BF2800 1 None None None 60682055 Common - putative aminopeptidase BF2576 245 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 60683224 Common - hypothetical protein BF3779 9 COG1409 Icc, Predicted phosphohydrolases General function prediction only 60681431 Common - coproporphyrinogen III oxidase BF1942 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 60680401 Common - putative desulfatase BF0850 19 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 60680473 Common panC putative pantoate--beta-alanine ligase BF0924 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 60680904 Pathogen - putative outer membrane protein BF1390 3 None None None 60680860 Common - putative transcriptional regulatory protein BF1344 158 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 60681534 Common - hypothetical protein BF2049 2 None None None 60680719 Common ktrA putative K+/Na+ uptake protein BF1194 102 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 60681317 Common - putative transmembrane protease BF1825 25 None None None 60680689 Common - 50S ribosomal protein L25/general stress protein Ctc BF1164 174 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 60681488 Common - putative polysialic acid capsule transport protein BF2000 96 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 60683769 Pathogen - hypothetical protein BF4358 1 None None None 60682996 Common - conserved hypothetical dehydrogenase protein BF3538 213 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 60680058 Common - putative glutamate:gamma-aminobutyrate antiporter BF0487 139 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 60681161 Pathogen - hypothetical protein BF1667 1 COG4980 GvpP, Gas vesicle protein General function prediction only 60681796 Pathogen - hypothetical protein BF2318 1 None None None 60682465 Pathogen - hypothetical protein BF2995 2 None None None 60682849 Common - putative ArsC family related protein BF3387 68 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 60682903 Common - putative polyA polymerase BF3442 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 60681388 Common aepY putative LPS biosynthesis related phosphoenolpyruvate decarboxylase BF1898 57 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 60683401 Common hutH putative histidine ammonia-lyase BF3966 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 60682353 Common - hypothetical protein BF2883 17 COG5464 COG5464, Uncharacterized conserved protein Function unknown 60680046 Pathogen - hypothetical protein BF0473 1 None None None 60682244 Common - putative phosphate-related ABC transport system, exported protein BF2772 151 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 60681525 Pathogen - putative transmembrane protein BF2039 1 None None None 60683570 Common - putative haloacid dehalogenase-type hydrolase BF4148 44 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 60682578 Common - hypothetical protein BF3109 6 None None None 60682892 Common - putative lipoprotein BF3430 3 None None None 60682137 Common asnB asparagine synthetase B BF2661 158 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 60679780 Common - putative lipopolysaccharide core biosynthesis protein BF0185 8 None None None 60681215 Common - hypothetical protein BF1723 3 None None None 60681906 Pathogen - putative lipoprotein BF2427 1 None None None 60681342 Pathogen - hypothetical protein BF1851 1 None None None 60682946 Common - putative transport-related, membrane protein BF3486 213 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60679741 Common - putative exported signal peptidase I BF0145 125 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 60681188 Common thrS putative threonyl-tRNA synthetase BF1694 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60683641 Common - putative transmembrane rhomboid family protein BF4221 137 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 60680608 Common - hypothetical protein BF1071 32 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 60682815 Common - putative transport related, lipoprotein BF3350 120 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60683064 Common - hypothetical protein BF3614 8 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 60680905 Common - hypothetical protein BF1393 20 None None None 60681258 Common traF putative transmembrane conserved protein found in conjugate transposon BF1766 3 None None None 60683190 Common - putative RNA polymerase sigma factor BF3744 88 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60679913 Common - hypothetical protein BF0324 46 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 60679974 Common - putative sodium-dependent transporter BF0389 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 60682443 Pathogen - hypothetical protein BF2973 1 None None None 60679602 Pathogen - hypothetical protein BF0005 1 None None None 60681754 Pathogen - hypothetical protein BF2275 3 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60680498 Common - putative FtsK/SpoIIIE-like protein BF0950 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 60681499 Pathogen - putative transmembrane protein BF2011 1 None None None 60679977 Common - putative transporter/antibiotic resistance protein BF0392 82 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60680515 Common - putative RNA polymerase ECF-type sigma factor BF0969 121 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60683683 Pathogen - hypothetical protein BF4265 1 None None None 60683774 Common - putative lipase/esterase BF4363 83 COG0657 Aes, Esterase/lipase Lipid metabolism 60680377 Common - hypothetical protein BF0826 5 None None None 60681783 Pathogen - hypothetical protein BF2305 1 None None None 60682484 Common - hypothetical protein BF3014 57 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 60683182 Common - putative TonB exported protein BF3737 5 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 60680659 Pathogen - hypothetical protein BF1132 2 None None None 60680127 Common - cofactor-independent phosphoglycerate mutase BF0559 51 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 60680240 Common - putative outer membrane protein BF0681 54 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60683158 Common - putative N-acetylneuraminate lyase (sialic acid lyase) BF3713 231 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 60683084 Common rprY two-component system, transcriptional regulatory protein BF3634 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 60681583 Common - GTPase EngB BF2101 188 COG0218 COG0218, Predicted GTPase General function prediction only 60681252 Common - hypothetical protein BF1760 4 None None None 60683539 Common - flavodoxin BF4115 31 COG0716 FldA, Flavodoxins Energy production and conversion 60679903 Common - hypothetical protein BF0314 2 None None None 60680970 Common - hypothetical protein BF1467 4 None None None 60680465 Common - putative FNR-like protein BF0916 6 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 60682119 Common - hypothetical protein BF2640 38 COG4747 COG4747, ACT domain-containing protein General function prediction only 60682789 Pathogen - putative lipoprotein BF3321 1 None None None 60682206 Pathogen - putative lipoprotein BF2733 2 None None None 60683134 Common - putative alpha-1,2-fucosyltransferase BF3688 20 None None None 60683682 Common - hypothetical protein BF4264 17 COG4485 COG4485, Predicted membrane protein Function unknown 60683187 Pathogen - hypothetical protein BF3741A 1 None None None 60680728 Common - hypothetical protein BF1205 5 None None None 60681519 Pathogen - hypothetical protein BF2031 1 None None None 60681844 Common - hypothetical protein BF2364 3 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 60682674 Common - putative exported beta-galactosidase BF3205 73 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60681377 Common fcl putative GDP-L-fucose synthetase BF1887 150 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60679947 Common - putative nitroimidazole resistance-like protein BF0359 18 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 60682183 Pathogen - hypothetical protein BF2710 1 None None None 60681191 Common rplT 50S ribosomal protein L20 BF1697 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 60683041 Common - putative DNA topoisomerase BF3590 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 60681324 Pathogen - hypothetical protein BF1832 1 None None None 60680288 Pathogen upgZ putative transcriptional regulator BF0732 1 None None None 60680556 Common wcfA putative acetyl transferase BF1013 169 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 60682536 Common - putative lipoprotein BF3067 5 None None None 60679944 Pathogen - hypothetical protein BF0356 1 None None None 60680008 Common - putative glycosyltransferase BF0429 188 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60682034 Common - putative carboxynorspermidine decarboxylase BF2554 61 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 60679767 Pathogen - putative lipoprotein BF0172 1 None None None 60680101 Common kdpD putative osmosensitive potassium transport sensor protein BF0532 90 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 60679810 Common fucP putative L-fucose permease BF0215 46 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 60683329 Common recQ1 putative ATP-dependent DNA helicase BF3892 234 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 60683263 Common - putative dehydrogenase BF3820 52 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 60681148 Common - putative 2-oxoglutarate synthase subunit BF1653 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 60682014 Common cobB cobyrinic acid A,C-diamide synthase BF2534 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 60681221 Pathogen - hypothetical protein BF1729 1 None None None 60680316 Common - putative lipoprotein BF0761 2 None None None 60682596 Common - hypothetical protein BF3127 90 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 60680642 Common - hypothetical protein BF1112 32 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 60680097 Common kdpA potassium-transporting ATPase subunit A BF0528 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 60681019 Common - hypothetical protein BF1518 3 None None None 60683220 Common - putative exported serine protease, subtilase family BF3775 113 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 60681518 Common - putative tautomerase BF2030 10 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 60681458 Common - possible anti-sigma factor BF1970 19 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60680815 Common prfC putative peptide chain release factor 3 BF1297 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 60680089 Common - putative arylsulfatase BF0520 90 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60681663 Pathogen - putative lipoprotein BF2184 2 None None None 60681419 Pathogen - hypothetical protein BF1930 1 None None None 60682396 Common - hypothetical protein BF2926 22 None None None 60681886 Pathogen - hypothetical protein BF2407 1 None None None 60680102 Common frrD putative two-component sensor histidine kinase BF0533 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 60682755 Common - hypothetical protein BF3287 2 None None None 60682665 Common - putative two-component system, response regulator BF3196 179 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 60680538 Common - hypothetical protein BF0994 18 None None None 60683227 Common - redox-sensing transcriptional repressor Rex BF3782 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 60683244 Pathogen aapF hypothetical protein BF3799 1 None None None 60681062 Common - putative transmembrane protein BF1561 7 None None None 60681231 Pathogen - hypothetical protein BF1739 1 None None None 60679750 Common - putative outer membrane lipoprotein BF0154 131 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60681812 Common - hypothetical protein BF2334 14 None None None 60680284 Pathogen - hypothetical protein BF0728 1 None None None 60680466 Common - putative transmembrane protein BF0917 90 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 60682434 Common - putative glycosyltransferase BF2964 177 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60680457 Common - putative outer membrane protein BF0908 9 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 60680656 Pathogen - putative transmembrane protein BF1127 1 None None None 60683159 Common - putative GntR-family regulatory protein BF3714 92 COG2186 FadR, Transcriptional regulators Transcription 60680741 Common - putative DNA mismatch repair MutS protein BF1218 204 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 60681563 Common - glycine dehydrogenase BF2079 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 60680160 Common - hypothetical protein BF0594 12 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60681059 Common - putative glyocosyltransferase protein BF1558 25 None None None 60679681 Common - putative iron-sulfur cluster-binding protein BF0085 130 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 60679630 Pathogen - hypothetical protein BF0033 1 None None None 60680722 Common - putative ECF-type RNA polymerase sigma factor BF1197 135 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60683097 Common - putative glycosyl transferase BF3648 136 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 60683766 Common - putative UDP-glucose 4-epimerase BF4355 203 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60682956 Common - putative glycoprotease family exported protein BF3497 168 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 60679723 Pathogen - hypothetical protein BF0127 1 None None None 60683659 Pathogen - putative transmembrane protein BF4241 1 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 60681043 Pathogen - hypothetical protein BF1542 1 None None None 60682660 Common - hypothetical protein BF3191 106 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60680247 Common - putative AraC-family transcriptional regulator BF0688 48 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60682179 Pathogen - putative lipoprotein BF2706 1 None None None 60683006 Common - putative acyl-ACP thioesterase BF3548 24 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 60680915 Pathogen - hypothetical protein BF1403 1 None None None 60683408 Pathogen - putative transmembrane protein BF3973 1 None None None 60681276 Pathogen - hypothetical protein BF1784 1 None None None 60682627 Common - hypothetical protein BF3158 37 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 60683503 Pathogen - putative transmembrane protein BF4079 1 None None None 60680991 Pathogen - putative conserved TraI-like protein found in conjugate transposon BF1489 1 None None None 60681695 Common - putative MatE-family transport-related membrane protein BF2216 146 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60682004 Common cbiP cobyric acid synthase BF2524 154 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 60681206 Common - putative N-acetylneuraminate lyase BF1712 198 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 60682391 Common - putative arsenate reductase BF2921 13 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 60680632 Pathogen - hypothetical protein BF1101 1 None None None 60681274 Common - putative ParB-family protein BF1782 185 COG1475 Spo0J, Predicted transcriptional regulators Transcription 60682950 Common - putative protease BF3491 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 60683115 Pathogen - putative lipoprotein BF3666 2 None None None 60683593 Common - putative carboxy-terminal processing protease precursor BF4172 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 60683309 Pathogen - hypothetical protein BF3867 1 None None None 60680141 Common - putative beta-galactosidase BF0573 76 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60681633 Common - putative cation transport related membrane protein BF2154 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 60680047 Common - hypothetical protein BF0474 9 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 60683540 Pathogen - putative transmembrane protein BF4116 1 None None None 60680020 Common proA gamma-glutamyl phosphate reductase BF0443 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 60680435 Common dcp putative peptidyl-dipeptidase BF0884 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 60683259 Common - putative LPS biosynthesis-related glycosyltransferase BF3815 186 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60681339 Pathogen - hypothetical protein BF1848 3 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60680023 Common murI putative glutamate racemase BF0446 189 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 60680998 Common - putative peptidase BF1496 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 60679885 Common - putative exported endo-arabinase BF0292 44 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 60680194 Common - putative biotin/lipoate A/B protein ligase family protein BF0632 217 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 60680380 Common lpxD putative UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase BF0829 154 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 60680993 Pathogen - putative transmembrane protein BF1491 1 None None None 60682370 Common - putative exported hydrolase BF2900 125 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 60683215 Common trmB tRNA (guanine-N(7))-methyltransferase BF3770 101 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 60683492 Common - hypothetical protein BF4064 3 None None None 60680827 Common - putative anti-sigma factor BF1309 38 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60681162 Common - putative ATP-dependent RNA helicase BF1668 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 60682604 Common - putative MarR-family transcriptional regulator BF3135 69 COG1846 MarR, Transcriptional regulators Transcription 60681052 Common rmlA1 putative glucose-1-phosphate thymidyl transferase BF1551 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 60682882 Pathogen - hypothetical protein BF3420 1 None None None 60681003 Pathogen - hypothetical protein BF1501 1 None None None 60681176 Common - hypothetical protein BF1682 4 None None None 60680566 Common wcfI putative glycosyltransferase BF1023 133 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60682927 Common uphY putative LPS biosynthesis related transcriptional regulatory protein BF3466 4 COG0250 NusG, Transcription antiterminator Transcription 60683103 Common - putative S-adenosylmethionine:tRNA ribosyltransferase-isomerase BF3654 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 60680225 Common aroA putative 3-phosphoshikimate 1-carboxyvinyltransferase BF0666 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 60683447 Pathogen - hypothetical protein BF4012 1 None None None 60680015 Pathogen - hypothetical protein BF0437 1 None None None 60683125 Common - hypothetical protein BF3676 50 COG0824 FcbC, Predicted thioesterase General function prediction only 60683718 Common - putative glycosyltransferase BF4306 167 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60681595 Common - possible DNA-binding protein BF2114 4 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 60682962 Common rffG putative dTDP-glucose 4,6-dehydratase BF3504 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 60681091 Pathogen - hypothetical protein BF1595 1 None None None 60680837 Pathogen - hypothetical protein BF1319 2 None None None 60683334 Common - putative RNA-binding protein BF3897 65 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 60682749 Common - hypothetical protein BF3281 3 None None None 60680644 Common - hypothetical protein BF1114 26 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 60682637 Common nifJ putative pyruvate-flavodoxin oxidoreductase BF3168 125 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 60680447 Pathogen - putative transmembrane protein BF0897 3 None None None 60679834 Common gpmI phosphoglyceromutase BF0241 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 60681931 Common - putative exported outer membrane protein BF2451 22 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60682780 Common - uracil-DNA glycosylase BF3312 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 60683281 Pathogen - hypothetical protein BF3838 1 None None None 60683771 Pathogen - putative transmembrane protein BF4360 1 None None None 60683521 Pathogen - hypothetical protein BF4097 1 None None None 60681120 Common accC1 putative biotin carboxylase 1 BF1624 228 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 60681581 Common - putative ATP-binding ABC transporter protein BF2099 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 60682424 Common - hypothetical protein BF2954 48 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 60683676 Common typA putative GTP-binding elongation factor family protein TypA/BipA BF4258 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 60680134 Common - putative transmembrane protein BF0566 188 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 60682094 Common rnfE SoxR-reducing system protein RsxE BF2615 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 60681098 Common - putative transmembrane permease BF1602 178 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 60682216 Common - putative V(vacuolar)-type Na+-ATP synthase subunit K BF2743 21 None None None 60682227 Common - hypothetical protein BF2755 5 None None None 60679779 Common - putative lipopolysaccharide 1,2-glucosyltransferase/general stress protein BF0184 33 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 60683430 Common rpmC 50S ribosomal protein L29 BF3995 8 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 60680094 Common - putative pyridine nucleotide oxidoreductase BF0525 244 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 60679744 Common - hypothetical protein BF0148 7 None None None 60680937 Common - putative hemagglutinin BF1428 72 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 60680873 Pathogen - hypothetical protein BF1357 1 None None None 60680545 Common secG preprotein translocase subunit SecG BF1001 7 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 60681511 Common - putative ATP-dependent protease BF2023 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 60682709 Pathogen - putative lipoprotein BF3240 2 None None None 60683565 Pathogen - putative transmembrane protein BF4144 1 None None None 60681467 Common - hypothetical protein BF1979 33 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 60680708 Pathogen - hypothetical protein BF1183 1 None None None 60681603 Common - putative aldo/keto reductase BF2122 205 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 60683321 Pathogen - hypothetical protein BF3884 1 None None None 60681021 Common mobC mobilisation protein C BF1520 13 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 60681460 Common - putative AraC family transcriptional regulator BF1972 7 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60680842 Pathogen - hypothetical protein BF1324 1 None None None 60680901 Common - putative transmembrane AraC family transcriptional regulator BF1387 25 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60683737 Common - putative transmembrane sugar transporter BF4325 180 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60683364 Common - putative protease BF3927 186 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 60682313 Common - putative anti-anti sigma factor BF2843 22 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 60680229 Common - putative transmembrane acyltransferase protein BF0670 19 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 60679626 Common - putative beta-galactosidase BF0029 73 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60683198 Common - putative exported peptidase BF3752 133 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 60683033 Common - hypothetical protein BF3580 5 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 60683581 Common - putative RNA polymerase sigma-54 factor BF4160 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 60679663 Common - hypothetical protein BF0067 5 None None None 60680957 Common - aspartate aminotransferase BF1452 87 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 60681927 Common - putative conserved membrane protein BF2447 35 COG4828 COG4828, Predicted membrane protein Function unknown 60683232 Common rplM 50S ribosomal protein L13 BF3787 226 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 60680844 Pathogen - putative transmembrane protein BF1326 1 None None None 60681557 Common serA putative D-3-phosphoglycerate dehydrogenase BF2073 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 60679861 Common - hypothetical protein BF0268 2 COG1470 COG1470, Predicted membrane protein Function unknown 60682416 Common acrD putative aminoglycoside efflux pump BF2946 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60683427 Common rplX 50S ribosomal protein L24 BF3992 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 60682843 Common - putative amino acid transport related, membrane protein BF3381 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 60680291 Common - putative capsular polysaccharide related hexapeptide transferase family protein BF0735 197 COG1043 LpxA, Acyl- acyl carrier protein 60681717 Common - putative cation efflux-related outer membrane exported protein BF2238 45 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60681367 Common - putative TonB-dependent outer membrane protein BF1876 111 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60680018 Common - hypothetical protein BF0440 25 None None None 60680893 Common - putative transmembrane sodium/sulfate transporter BF1379 167 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 60681872 Common tgt queuine tRNA-ribosyltransferase BF2392 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 60682929 Common - hypothetical protein BF3469 31 COG5545 COG5545, Predicted P-loop ATPase and inactivated derivatives General function prediction only 60681636 Common - putative lipoprotein BF2157 22 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 60682293 Common - putative nucleotidase BF2822 127 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 60682400 Common - putative antibiotic resistance transport membrane protein BF2930 196 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60682200 Common - hypothetical protein BF2727 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 60681714 Common atpG ATP synthase gamma chain BF2235 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 60683636 Common - hypothetical protein BF4216 6 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60681249 Pathogen - putative transmembrane protein BF1757 1 None None None 60682833 Common - putative peptidoglycan biosynthesis-related protein BF3370 123 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 60680942 Common - putative ABC transporter permease component BF1433 38 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60683017 Pathogen - putative lipoprotein BF3559 1 None None None 60683707 Pathogen - hypothetical protein BF4295 1 None None None 60681522 Pathogen - hypothetical protein BF2036 1 None None None 60682630 Pathogen - hypothetical protein BF3161 1 None None None 60680236 Common - hypothetical protein BF0677 6 None None None 60680941 Common - putative ABC transporter permease component BF1432 5 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60682544 Common - hypothetical protein BF3075 6 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60679644 Pathogen - hypothetical protein BF0047 1 None None None 60682735 Common leuD putative 3-isopropylmalate dehydratase small subunit BF3265 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 60679606 Pathogen - putative glycosyltransferase BF0009 1 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 60682345 Common - hypothetical protein BF2875 4 None None None 60681775 Pathogen - hypothetical protein BF2297 1 None None None 60681700 Common - putative transport-related membrane protein BF2221 15 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60680798 Common - putative sulfatase protein BF1280 74 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60682195 Common - putative regulatory protein BF2722 146 COG1733 COG1733, Predicted transcriptional regulators Transcription 60681313 Common - putative RNA polymerase ECF-type sigma factor BF1821 154 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60682203 Pathogen - hypothetical protein BF2730 2 None None None 60681720 Common - putative two component system response regulator BF2241 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 60681680 Common - putative ligase BF2201 214 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 60682159 Common - putative acetyltransferase BF2685 200 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 60681625 Common - putative RibD-family protein BF2146 32 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 60681371 Pathogen - hypothetical protein BF1881 2 None None None 60682885 Pathogen - hypothetical protein BF3423 1 None None None 60683252 Common carB2 putative carbamoyl-phosphate synthase large chain 2 BF3808 232 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 60679704 Common - putative deoxyribose-phosphate aldolase BF0108 134 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 60682180 Pathogen - putative lipoprotein BF2707 1 None None None 60681114 Common - putative outer membrane receptor protein BF1618 17 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60680351 Common - hypothetical protein BF0799 44 COG2267 PldB, Lysophospholipase Lipid metabolism 60681094 Common - putative endo-beta-galactosidase BF1598 44 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 60682700 Common - hypothetical protein BF3231 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 60682822 Pathogen - hypothetical protein BF3357 3 None None None 60681069 Common hup1 putative histone-like DNA-binding protein HU1 BF1568 188 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60683292 Common - putative regulatory protein BF3850 214 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 60681010 Common cbh putative choloylglycine hydrolase BF1508 54 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 60681821 Common - putative glutamine synthetase I BF2343 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 60679848 Common ftsW putative transmembrane rod-shape determining protein BF0255 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 60681195 Common - indolepyruvate oxidoreductase subunit B BF1701 100 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 60683302 Common - putative hydrolase BF3860 155 COG0546 Gph, Predicted phosphatases General function prediction only 60682874 Common omp117 putative outer membrane protein Omp117 BF3412 12 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682024 Pathogen - hypothetical protein BF2544 1 None None None 60683363 Common - putative transmembrane transport efflux protein BF3926 157 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60681105 Common - putative FtsX-related transporter permease BF1609 58 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60683439 Common rpsJ 30S ribosomal protein S10 BF4004 243 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 60680518 Common - hypothetical protein BF0972 5 None None None 60682222 Common - putative V-type ATP synthase subunit E BF2749 10 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 60682469 Common - hypothetical protein BF2999 7 None None None 60681967 Common - putative chloramphenicol acetyltransferase BF2487 22 COG4845 COG4845, Chloramphenicol O-acetyltransferase Defense mechanisms 60682933 Pathogen - hypothetical protein BF3473 3 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60683376 Common - putative GntR family transcriptional regulator BF3939 53 COG1725 COG1725, Predicted transcriptional regulators Transcription 60683645 Common - bifunctional preprotein translocase subunit SecD/SecF BF4225 221 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 60681657 Common - putative AraC-family transcriptional regulator BF2178 48 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60682152 Common trpF N-(5'-phosphoribosyl)anthranilate isomerase BF2677 180 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 60682995 Common pfkA 6-phosphofructokinase BF3537 152 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 60680116 Pathogen - hypothetical protein BF0547 1 None None None 60681485 Common - hypothetical protein BF1997 4 None None None 60681440 Pathogen - hypothetical protein BF1951 1 None None None 60682322 Common - hypothetical protein BF2852 12 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 60682076 Common - putative LPS biosynthesis related glycosyltransferase BF2597 157 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60682506 Common - putative exported transglycosylase protein BF3036 116 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 60680616 Common - hypothetical protein BF1080 99 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 60682250 Common - hypothetical protein BF2778 18 COG3247 HdeD, Uncharacterized conserved protein Function unknown 60682475 Pathogen - hypothetical protein BF3005 1 COG3710 CadC, DNA-binding winged-HTH domains Transcription 60679651 Pathogen - hypothetical protein BF0055 1 None None None 60681109 Pathogen - hypothetical protein BF1613 1 None None None 60683021 Pathogen - hypothetical protein BF3563 3 None None None 60683343 Pathogen - hypothetical protein BF3906 1 None None None 60683586 Common - hypothetical protein BF4165 47 COG4099 COG4099, Predicted peptidase General function prediction only 60682656 Common - hypothetical protein BF3187 16 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 60682729 Common - putative UDP-glucuronic acid epimerase BF3259 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60682913 Common rfbC1 putative LPS biosynthesis related dTDP-4-dehydrorhamnose 3,5-epimerase BF3452 169 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 60681074 Common - hypothetical protein BF1573 7 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 60683620 Pathogen - hypothetical protein BF4199 1 None None None 60680585 Common - putative C4-dicarboxylate anaerobic carrier BF1046 49 COG1288 COG1288, Predicted membrane protein Function unknown 60683269 Common - putative glycosyltransferase BF3826 199 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60680366 Common - putative Sec-independent protein translocase component BF0814 202 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 60680718 Common ktrB putative transmembrane K+/Na+ uptake protein BF1193 87 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 60682513 Pathogen - hypothetical protein BF3043 2 None None None 60683089 Common - putative oxygen-independent coproporphyrinogen III oxidase BF3638 221 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 60683578 Common - hypothetical protein BF4156 17 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 60680327 Common - putative cation symporter BF0773 93 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 60682358 Common hisI histidine biosynthesis bifunctional protein BF2888 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 60682245 Common glnS glutaminyl-tRNA synthetase BF2773 241 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 60681831 Common sucC succinyl-CoA synthetase beta chain BF2351 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 60683091 Pathogen - hypothetical protein BF3640 1 None None None 60682144 Common - polyphosphate kinase BF2668 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 60683760 Common - putative DNA processing Smf-like protein BF4349 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 60682440 Common - hypothetical protein BF2970 7 None None None 60680664 Common trmE tRNA modification GTPase TrmE BF1138 226 COG0486 ThdF, Predicted GTPase General function prediction only 60681110 Common bioD dithiobiotin synthetase BF1614 156 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 60679894 Common - putative exported glycosylhydrolase BF0303 42 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 60681550 Common nqrB Na(+)-translocating NADH-quinone reductase subunit B BF2066 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 60682891 Pathogen - hypothetical protein BF3429 1 None None None 60682884 Common - putative DNA-binding protein BF3422 4 None None None 60680956 Common - putative two component sensor histidine kinase protein BF1451 211 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 60682265 Common - hypothetical protein BF2794 16 None None None 60683783 Common leuS leucyl-tRNA synthetase BF4372 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60681780 Pathogen - hypothetical protein BF2302 1 None None None 60681905 Pathogen - hypothetical protein BF2426 1 None None None 60679946 Common - putative transmembrane protein BF0358 30 None None None 60681506 Pathogen - hypothetical protein BF2018 1 None None None 60680009 Common efp elongation factor P BF0431 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 60679943 Common - putative fkbp-type 22 kDa peptidyl-prolyl cis-trans isomerase BF0355 81 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 60682859 Common - hypothetical protein BF3397 98 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 60679757 Common cysS cysteinyl-tRNA synthetase BF0161 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60682670 Common - putative lipoprotein BF3201 31 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 60680764 Pathogen - hypothetical protein BF1244 1 None None None 60681345 Pathogen - hypothetical protein BF1854 1 None None None 60681509 Common - hypothetical protein BF2021 2 None None None 60681189 Common infC translation initiation factor IF-3 BF1695 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 60682287 Common - hypothetical protein BF2816 3 None None None 60680557 Common wzx2 putative O-antigen flippase BF1014 10 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 60683646 Common hup4 putative histone-like DNA-binding protein HU4 BF4226 204 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60680771 Common - hypothetical protein BF1251 2 None None None 60683573 Common - putative transmembrane Na+/Pi-cotransporter BF4151 89 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 60680609 Pathogen - hypothetical protein BF1072 2 COG1203 COG1203, Predicted helicases General function prediction only 60681032 Pathogen - hypothetical protein BF1531 1 None None None 60679835 Common - putative two-component system sensor kinase BF0242 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60683686 Common - putative anti-sigma factor BF4270 10 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60680444 Common - putative enoyl-[acyl-carrier-protein] reductase [NADH] BF0894 170 COG0623 FabI, Enoyl- acyl-carrier-protein 60680052 Common argD putative acetylornithine aminotransferase BF0479 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 60679973 Common - hypothetical protein BF0388 9 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 60682037 Pathogen - putative thiamine biosynthesis-related protein BF2557 1 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 60680627 Pathogen - hypothetical protein BF1096 1 None None None 60680394 Common - hypothetical protein BF0843 50 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 60681939 Common - putative ABC transport system, ATP-binding protein BF2459 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 60682647 Common - hypothetical protein BF3178 5 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680522 Common - putative anti-sigma factor BF0976 30 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60682277 Common - hypothetical protein BF2806 16 None None None 60683168 Common - hypothetical protein BF3723 6 None None None 60680371 Common - putative regulatory protein BF0820 27 COG3682 COG3682, Predicted transcriptional regulator Transcription 60681496 Common - putative transmembrane protein BF2008 2 COG3356 COG3356, Predicted membrane protein Function unknown 60681580 Common - putative transporter permease protein BF2098 16 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60681968 Common - hypothetical protein BF2488 39 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 60679718 Pathogen - hypothetical protein BF0122 1 None None None 60681592 Common - putative bacteriophage integrase BF2111 25 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60679993 Pathogen - hypothetical protein BF0413 1 None None None 60681795 Pathogen - hypothetical protein BF2317 1 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 60683226 Common - putative hydrolase BF3781 178 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 60682086 Common fkp bifunctional fucokinase/L-fucose-1-P-guanylyltransferase BF2607 30 COG2605 COG2605, Predicted kinase related to galactokinase and mevalonate kinase General function prediction only 60680001 Common - hypothetical protein BF0422 5 None None None 60682304 Common - hypothetical protein BF2833 9 None None None 60682786 Common - hypothetical protein BF3318 30 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 60679639 Pathogen - hypothetical protein BF0042 1 None None None 60681892 Pathogen - hypothetical protein BF2413 1 None None None 60681544 Pathogen - putative transmembrane surface-related protein BF2060 2 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 60683759 Pathogen - putative transmembrane protein BF4348 3 None None None 60682048 Common - putative RNA methyltransferase BF2568 193 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 60682162 Common - 5-aminoimidazole-4-carboxamide ribonucleotide transformylase BF2688 218 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 60680582 Common dinB putative DNA polymerase IV BF1043 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 60680778 Common - hypothetical protein BF1258 4 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 60680292 Common - putative sugar-phosphate nucleotidyl transferase BF0736 183 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 60682640 Common opuAB putative glycine betaine transport system permease protein BF3171 200 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 60680452 Common - hypothetical protein BF0903 68 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 60681080 Common - hypothetical protein BF1581 2 None None None 60681039 Common - putative phage integrase/recombinase BF1538 215 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60681245 Pathogen - hypothetical protein BF1753 1 None None None 60682138 Common - hypothetical protein BF2662 70 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 60681481 Common - hypothetical protein BF1993 6 None None None 60683402 Common - putative formiminotransferase-cyclodeaminase BF3967 39 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 60681670 Common - hypothetical protein BF2191 14 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 60680152 Common - hypothetical protein BF0586 21 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60683712 Common - putative exopolysaccharide biosynthesis protein BF4300 6 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60681040 Pathogen - hypothetical protein BF1539 1 None None None 60681867 Pathogen - putative lipoprotein BF2387 1 None None None 60680474 Common panD aspartate alpha-decarboxylase BF0925 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 60681224 Common - hypothetical protein BF1732 3 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 60680922 Pathogen - hypothetical protein BF1411 1 None None None 60681911 Pathogen - hypothetical protein BF2432 2 None None None 60680550 Common - putative transmembrane protein BF1006 6 None None None 60680985 Pathogen - hypothetical protein BF1483 2 None None None 60682041 Pathogen - hypothetical protein BF2561 2 None None None 60681427 Common cydB putative cytochrome d ubiquinol oxidase subunit II BF1938 127 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 60681432 Common - hypothetical protein BF1943 14 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 60683077 Common - hypothetical protein BF3627 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 60679912 Common - hypothetical protein BF0323 28 COG3746 OprP, Phosphate-selective porin Inorganic ion transport and metabolism 60682677 Common - putative two-component system, sensor kinase BF3208 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60682525 Common ffh signal recognition particle protein BF3056 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 60682803 Common - putative K+ transport related membrane protein BF3336 211 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 60683208 Common - hypothetical protein BF3763 18 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 60682272 Common - putative glycosyltransferase protein BF2801 53 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60681218 Pathogen - hypothetical protein BF1726 1 None None None 60682068 Common - hypothetical protein BF2589 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 60681649 Common - putative polyketide synthesis O-methyltransferase BF2170 35 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 60681744 Pathogen - putative lipoprotein BF2265 2 None None None 60681566 Common - hypothetical protein BF2082 29 None None None 60682696 Pathogen - hypothetical protein BF3227 1 None None None 60679739 Common uxuB D-mannonate oxidoreductase BF0143 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 60683414 Common rpsM 30S ribosomal protein S13 BF3979 245 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 60682361 Common hisH imidazole glycerol phosphate synthase subunit HisH BF2891 218 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 60683332 Common - putative cell division trigger factor BF3895 190 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 60683606 Common - hypothetical protein BF4185 54 COG1359 COG1359, Uncharacterized conserved protein Function unknown 60681672 Common - putative hydrolase exported protein BF2193 61 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60680200 Common - putative phosphatidylserine synthase BF0639 154 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 60681802 Common - putative single-strand binding protein BF2324 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 60682233 Common - putative heat shock-related protease BF2761 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 60680600 Pathogen - hypothetical protein BF1061 1 None None None 60683141 Common - putative nucleotidyltransferase BF3695 27 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 60680207 Pathogen - putative transmembrane protein BF0648 1 None None None 60680914 Pathogen - hypothetical protein BF1402 2 None None None 60680857 Pathogen - hypothetical protein BF1341 1 None None None 60681205 Common - putative ROK family transcriptional repressor protein BF1711 165 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 60679670 Pathogen - hypothetical protein BF0074 3 None None None 60681743 Pathogen - hypothetical protein BF2264 3 None None None 60679616 Common - putative sulfate permease transmembrane protein BF0019 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 60681942 Common - hypothetical protein BF2462 104 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 60682131 Pathogen - conserved hypothetical lipoprotein BF2654 2 None None None 60682323 Common - putative tRNA:rRNA methyltransferase BF2853 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 60682387 Common - putative restriction enzyme related protein BF2917 42 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 60680504 Common - hypothetical protein BF0957 5 None None None 60683112 Common - biotin synthase BF3663 59 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 60680180 Pathogen - hypothetical protein BF0616 1 None None None 60679924 Common - putative two-component system sensor histidine kinase BF0335 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60683216 Common - putative hydrolase BF3771 61 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 60681257 Common traE putative transmembrane conserved protein found in conjugative transposon BF1765 3 None None None 60683063 Common - putative acetyltransferase BF3613 15 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 60680034 Common argH argininosuccinate lyase BF0457 226 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 60680184 Common - putative ErfK/YbiS/YcfS/YnhG family protein BF0621 34 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 60680415 Common - hypothetical protein BF0864 11 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60681351 Pathogen - hypothetical protein BF1860 1 None None None 60680951 Common - putative ABC transporter permease component BF1445 68 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60683772 Common - putative 5-nitroimadazole antibiotic resistance protein BF4361 35 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 60680786 Common - hypothetical protein BF1267 10 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 60680353 Common - putative phosphoglycolate phosphatase BF0801 179 COG0546 Gph, Predicted phosphatases General function prediction only 60682554 Common - putative exported glycosyl hydrolase BF3085 58 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60682581 Pathogen - hypothetical protein BF3112 2 None None None 60681147 Common - putative 2-oxoglutarate synthase subunit BF1652A 55 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 60681079 Pathogen - hypothetical protein BF1580 1 None None None 60682942 Common - putative hemolysin BF3482 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 60680413 Pathogen - putative transmembrane protein BF0862 2 None None None 60679919 Common - hypothetical protein BF0330 38 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 60683270 Pathogen - hypothetical protein BF3827 2 COG4403 LcnDR2, Lantibiotic modifying enzyme Defense mechanisms 60681987 Common - putative oxidoreductase BF2507 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 60681020 Pathogen - hypothetical protein BF1519 1 None None None 60681182 Common - hypothetical protein BF1688 4 None None None 60682583 Common - putative endo-beta-galactosidase BF3114 42 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 60681579 Pathogen - hypothetical protein BF2097 1 None None None 60680881 Pathogen upaY putative LPS biosynthesis related transcriptional regulatory protein BF1367 2 COG0250 NusG, Transcription antiterminator Transcription 60683629 Pathogen - hypothetical protein BF4209 2 None None None 60683448 Common - putative transmembrane protein BF4013 18 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 60680378 Common lpxA UDP-N-acetylglucosamine acyltransferase BF0827 153 COG1043 LpxA, Acyl- acyl carrier protein 60681136 Pathogen - hypothetical protein BF1642 1 None None None 60681576 Common - putative two-component sensor histidine kinase protein BF2094 221 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 60680427 Common - hypothetical protein BF0876 11 None None None 60680074 Pathogen - hypothetical protein BF0504 1 None None None 60679677 Common - putative choline-sulfatase BF0081 90 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60680272 Common - hypothetical protein BF0713 24 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 60680709 Common - hypothetical protein BF1184 16 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 60681993 Common - hypothetical protein BF2513 10 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 60683744 Common - hypothetical protein BF4332 40 None None None 60683314 Pathogen - hypothetical protein BF3877 2 None None None 60683601 Common - putative pyruvate formate-lyase activating enzyme BF4180 91 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 60681071 Common - putative arylsulfatase BF1570 78 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60681169 Common cysC putative adenylylsulfate kinase BF1675 143 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 60682620 Common - putative AcrB/AcrD/AcrF family membrane protein BF3151 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60681762 Common - putative phage integrase BF2284 127 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60681959 Common - AMP nucleosidase BF2479 92 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 60682466 Pathogen - hypothetical protein BF2996 1 None None None 60683340 Common era GTP-binding protein Era BF3903 224 COG1159 Era, GTPase General function prediction only 60680172 Common - putative AcrB/AcrD/AcrF family efflux transporter BF0607 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60680210 Common - putative methanol denhydrogenase-related protein BF0651 174 COG0714 COG0714, MoxR-like ATPases General function prediction only 60682112 Common - putative regulatory protein BF2633 118 COG2606 EbsC, Uncharacterized conserved protein Function unknown 60682764 Common - hypothetical protein BF3296 7 None None None 60683275 Pathogen - hypothetical protein BF3832 1 None None None 60682570 Common ruvC Holliday junction resolvase BF3101 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 60682770 Common - hypothetical protein BF3302 18 None None None 60681856 Common - hypothetical protein BF2376 9 COG2259 COG2259, Predicted membrane protein Function unknown 60683410 Common rplQ 50S ribosomal protein L17 BF3975 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 60680267 Common - putative aminoacyl-histidine dipeptidase BF0708 67 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 60683452 Common rplJ 50S ribosomal protein L10 BF4017 88 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 60682877 Pathogen - putative lipoprotein BF3415 1 None None None 60681437 Common - putative UDP-N-acetylglucosamine 2-epimerase BF1948 150 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 60683455 Common nusG putative transcription antitermination protein BF4020 215 COG0250 NusG, Transcription antiterminator Transcription 60680690 Common - hypothetical protein BF1165 8 None None None 60682914 Common rffH1 putative LPS biosynthesis related glucose-1-phosphate thymidylyltransferase BF3453 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 60682318 Common - putative capsular polysaccharide biosynthesis protein BF2848 184 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60682710 Common - hypothetical protein BF3241 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 60681689 Common - putative ABC transport system, membrane protein BF2210 33 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 60682123 Common - hypothetical protein BF2644 78 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 60680341 Common nuoJ putative NADH dehydrogenase chain J BF0787 153 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 60682172 Common - hypothetical protein BF2699 41 COG2311 COG2311, Predicted membrane protein Function unknown 60679777 Pathogen - hypothetical protein BF0182 1 None None None 60680969 Pathogen - hypothetical protein BF1466 1 None None None 60680409 Common - putative sugar-proton symporter BF0858 157 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60683247 Common aapC hypothetical protein BF3802 4 None None None 60679953 Common - putative FNR-family transcriptional regulatory protein BF0365 36 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 60681457 Common - putative ECF-type RNA polymerase sigma factor BF1969 40 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60681664 Pathogen - hypothetical protein BF2185 3 None None None 60681854 Common - putative surface membrane protein BF2374 16 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 60683053 Common - putative phospholipids biosynthesis BF3603 211 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 60683754 Common - hypothetical protein BF4343 4 None None None 60683353 Common mreB putative rod-shape determining protein BF3916 219 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 60681152 Common - hypothetical protein BF1658 5 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 60680838 Common - putative RNA polymerase ECF-type sigma factor BF1320 161 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60683483 Common - hypothetical protein BF4055 15 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 60681237 Common - hypothetical protein BF1745 2 None None None 60680390 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase BF0839 219 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 60682497 Common hisB imidazole glycerol-phosphate dehydratase/histidinol phosphatase BF3027 218 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 60682371 Common - putative uroporphirinogen biosynthesis-related protein BF2901 102 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 60682767 Common - putative nitroreductase family protein BF3299 120 COG0778 NfnB, Nitroreductase Energy production and conversion 60680067 Pathogen - hypothetical protein BF0497 1 None None None 60682653 Common - hypothetical protein BF3184 84 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 60683428 Common rplN 50S ribosomal protein L14 BF3993 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 60680888 Common wcfP putative glycosyltransferase BF1374 123 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60681976 Pathogen - putative DNA-binding protein BF2496 3 None None None 60682214 Common - putative glycogen phosphorylase BF2741 148 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 60680482 Common - putative ATP-binding component of ABC transporter protein BF0933 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 60679711 Pathogen - hypothetical protein BF0115 1 None None None 60681757 Common - hypothetical protein BF2279 27 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 60683175 Common - hypothetical protein BF3730 6 None None None 60679805 Common fucR putative GntR-family regulatory protein BF0210 45 COG2188 PhnF, Transcriptional regulators Transcription 60681529 Common - putative TonB-dependent outer membrane receptor protein BF2044 47 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60683697 Common - hypothetical protein BF4282 195 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 60679682 Common - putative polysaccharide deacetylase BF0086 100 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 60681281 Pathogen - hypothetical protein BF1789 1 None None None 60682986 Common - hypothetical protein BF3528 5 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 60683485 Common - putative outer membrane protein BF4057 6 None None None 60680080 Common - putative ABC transporter ATP-binding protein BF0511 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 60680142 Common - putative glycosyl hydrolase BF0574 24 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 60680748 Pathogen - hypothetical protein BF1225 1 None None None 60681291 Common - putative ATP/GTP-binding protein BF1799 30 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 60680297 Common - hypothetical protein BF0741 6 None None None 60683202 Common - putative RNA polymerase sigma factor BF3756 72 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60681630 Pathogen - hypothetical membrane protein BF2151 2 None None None 60679638 Pathogen - hypothetical protein BF0041 1 None None None 60680075 Pathogen - hypothetical protein BF0505 1 None None None 60680788 Common - putative sugar O-acetyltransferase BF1269 204 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 60681721 Common - putative two component system sensor histidine kinase BF2242 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60682007 Pathogen - hypothetical plasmid-stabilisation protein BF2527 2 COG3668 ParE, Plasmid stabilization system protein General function prediction only 60679617 Common rbr putative rubrerythrin BF0020 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 60681532 Common - putative two-component system sensor kinase/response regulator fusion protein BF2047 226 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60683491 Common - putative outer membrane protein BF4063 6 None None None 60680916 Pathogen - hypothetical protein BF1404 1 None None None 60682814 Common - putative multidrug resistance/siderophore transport related, membrane protein BF3349 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60683365 Common - putative peptidyl-prolyl cis-trans isomerase BF3928 178 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 60683504 Common - putative bacteriophage integrase BF4080 120 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 60680226 Common - putative AraC-family regulatory protein BF0667 45 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60680755 Common - conserved hypothetical protein found in conjugate transposon BF1235 4 None None None 60681275 Common - hypothetical protein BF1783 3 COG4474 COG4474, Uncharacterized protein conserved in bacteria Function unknown 60683409 Pathogen - hypothetical protein BF3974 1 None None None 60679605 Common - putative glycosyltransferase BF0008 95 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60679610 Common - hypothetical protein BF0013 8 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 60680404 Common - putative GFO/IDH/MOCA family oxidoreductase BF0853 97 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 60680567 Common wcfJ putative glycosyltransferase BF1024 139 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60680643 Pathogen - hypothetical protein BF1113 1 None None None 60682075 Pathogen - putative LPS biosynthesis related polysaccharide polymerase BF2596 1 None None None 60680135 Pathogen - hypothetical protein BF0567 2 None None None 60679884 Pathogen - hypothetical protein BF0291 1 None None None 60680631 Common - putative ATP-binding protein BF1100 29 COG1106 COG1106, Predicted ATPases General function prediction only 60682017 Common - hypothetical protein BF2537 49 COG2966 COG2966, Uncharacterized conserved protein Function unknown 60682883 Pathogen - hypothetical protein BF3421 1 None None None 60681338 Pathogen - hypothetical protein BF1847 3 None None None 60681366 Pathogen - hypothetical protein BF1875 1 None None None 60683102 Common - hypothetical protein BF3653 8 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 60683124 Common - hypothetical protein BF3675 233 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 60679820 Common - hypothetical protein BF0226 103 COG0393 COG0393, Uncharacterized conserved protein Function unknown 60680861 Pathogen - hypothetical protein BF1345 2 None None None 60680657 Pathogen - hypothetical protein BF1128 2 None None None 60681312 Common - putative ABC transporter component BF1820 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 60681273 Pathogen - hypothetical protein BF1781 1 None None None 60681759 Common - putative two component system sensor histidine kinase BF2281 103 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 60680183 Pathogen - hypothetical protein BF0620 2 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 60683541 Pathogen - hypothetical protein BF4117 1 None None None 60680012 Common rluD ribosomal large subunit pseudouridine synthase BF0434 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 60681082 Common btuB putative vitamin B12 receptor BF1583 71 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60682042 Common thiH thiamine biosynthesis protein ThiH BF2562 54 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 60680807 Common pepT peptidase T BF1289 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 60681594 Pathogen - hypothetical protein BF2113 1 None None None 60682104 Common - putative inner membrane protein translocase component YidC BF2625 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 60682694 Pathogen - putative lipoprotein BF3225 1 None None None 60679627 Common - putative AraC family/two component family regulatory protein BF0030 17 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60681004 Common - putative protein involved in partitioning BF1502 209 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 60683719 Common cobB NAD-dependent deacetylase BF4307 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 60682485 Common - putative thioredoxin BF3015 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 60683514 Pathogen - hypothetical protein BF4090 3 COG5545 COG5545, Predicted P-loop ATPase and inactivated derivatives General function prediction only 60681659 Common - hypothetical protein BF2180 17 COG3969 COG3969, Predicted phosphoadenosine phosphosulfate sulfotransferase General function prediction only 60681073 Common - putative transmembrane CorC/HlyC family transporter associated protein BF1572 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 60679804 Pathogen - hypothetical protein BF0209 1 None None None 60681018 Common - hypothetical protein BF1517 5 None None None 60680889 Common wcfQ putative glycosyltransferase BF1375 61 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60680961 Common - putative type I RM modification enzyme BF1458 125 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 60682788 Common hdhA putative 7-alpha-hydroxysteroid dehydrogenase (bile acid catabolism) BF3320 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 60680299 Common - putative UDP-ManNAc dehydrogenase BF0743 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 60682860 Common - hypothetical protein BF3398 134 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 60680683 Common susB putative alpha-glucosidase BF1158 18 None None None 60681331 Common - putative type I restriction endonuclease specificity subunit, partial BF1840 13 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 60683773 Common cysK putative cysteine synthase BF4362 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 60682344 Pathogen - hypothetical protein BF2874 3 None None None 60683520 Pathogen - hypothetical protein BF4096 1 None None None 60682502 Common - putative Pirin-like protein BF3032 144 COG1741 COG1741, Pirin-related protein General function prediction only 60681051 Pathogen upfZ putative transcriptional regulator BF1550 1 None None None 60681634 Common - hypothetical protein BF2155 10 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60681528 Common - putative ABC transporter ATP-binding protein BF2043 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 60681054 Common - hypothetical protein BF1553 2 None None None 60683282 Common - putative phage integrase BF3839 57 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60682741 Common - putative bacterioferritin-related protein BF3271 36 COG2406 COG2406, Protein distantly related to bacterial ferritins General function prediction only 60682926 Pathogen uphZ putative LPS biosynthesis related transcriptional regulatory protein BF3465 1 None None None 60680254 Common parB putative ParB-like chromosome partitioning protein BF0695 188 COG1475 Spo0J, Predicted transcriptional regulators Transcription 60681292 Pathogen - hypothetical protein BF1800 1 None None None 60680868 Common - putative ATP-binding PP-loop protein BF1352 217 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 60680230 Common - hypothetical protein BF0671 4 None None None 60680449 Common - putative dipeptidyl peptidase BF0899 104 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 60682495 Common - hypothetical protein BF3025 5 None None None 60680095 Common - putative aspartate kinase BF0526 190 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 60680448 Common - lipoyl synthase BF0898 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 60680820 Common - hypothetical protein BF1302 3 None None None 60681016 Common - putative RNA polymerase ECF-type sigma factor BF1514 45 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60681845 Common - hypothetical protein BF2365 10 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 60682778 Common - putative transport-related membrane protein BF3310 85 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60681234 Pathogen - hypothetical protein BF1742 2 None None None 60683556 Pathogen - hypothetical protein BF4135 1 None None None 60683615 Common - putative lipopolysaccharide biosynthesis protein BF4194 16 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 60683679 Common - acyl-CoA synthetase BF4261 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 60682668 Common - hypothetical protein BF3199 9 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60679698 Pathogen - hypothetical protein BF0102 1 None None None 60680042 Pathogen - putative transmembrane protein BF0469 1 None None None 60680481 Common - putative lipoprotein BF0932 125 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 60680800 Common - putative transmembrane protein BF1282 118 COG2855 COG2855, Predicted membrane protein Function unknown 60683098 Pathogen - hypothetical protein BF3649 1 None None None 60683706 Common - putative transmembrane anchored hypothetical protein BF4294 4 None None None 60681030 Common rteA putative two component system sensor kinase BF1529 3 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 60681747 Common - putative peroxidase family protein BF2268 50 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 60681887 Pathogen - hypothetical protein BF2408 1 None None None 60681660 Common - hypothetical protein BF2181 17 COG1475 Spo0J, Predicted transcriptional regulators Transcription 60682228 Common - putative lipoprotein BF2756 5 None None None 60682752 Common bmgB mobilization protein BF3284 5 None None None 60683264 Common - putative regulatory protein BF3821 60 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 60681871 Common - hypothetical protein BF2391 69 COG0795 COG0795, Predicted permeases General function prediction only 60680981 Common - hypothetical protein BF1479 7 None None None 60679852 Common ftsI putative cell division specific transpeptidase/penicillin-binding protein BF0259 206 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 60681455 Pathogen - hypothetical protein BF1966 1 None None None 60683431 Common rplP 50S ribosomal protein L16 BF3996 218 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 60680490 Pathogen - hypothetical protein BF0941 1 None None None 60681300 Common estA sialate-O-acetyltransferase BF1808 30 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 60679758 Common - putative haloacid dehalogenase-like hydrolase BF0163 147 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 60683397 Common - putative transmembrane Acr-type transport protein BF3962 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60681400 Common wcgT putative LPS biosynthesis related epimerase BF1910 155 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 60680248 Common alaS alanyl-tRNA synthetase BF0689 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60680963 Common - hypothetical protein BF1460 16 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 60681044 Pathogen - hypothetical protein BF1543 1 None None None 60683152 Common - hypothetical protein BF3707 92 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 60680497 Pathogen - conserved hypothetical protein, possible C-terminal metal binding site BF0949 3 None None None 60682771 Common - hypothetical protein BF3303 16 None None None 60683355 Common pepO putative endopeptidase BF3918 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 60683529 Common - putative aldo/keto reductase BF4105 135 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 60683328 Common guaB putative inosine-5'-monophosphate dehydrogenase BF3891 243 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 60680309 Pathogen - putative non-specific DNA binding protein BF0754 3 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60683782 Pathogen - putative ATP/GTP-binding protein BF4371 2 None None None 60680572 Common - putative TonB-dependent outer membrane receptor protein BF1029 125 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60681829 Pathogen - hypothetical protein BF2349 1 None None None 60681395 Common wcfZ putative LPS biosynthesis related glycosyltransferase BF1905 150 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60682823 Common - putative permease/membrane protein BF3358 7 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 60683660 Common ugpQ putative glycerophosphoryl diester phosphodiesterase BF4242 119 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 60682754 Pathogen - hypothetical protein BF3286 1 None None None 60680283 Common - hypothetical protein BF0727 7 None None None 60682399 Common - putative AraC-family regulatory protein BF2929 73 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60683667 Common - putative outer membrane protein BF4249 4 None None None 60680519 Common - putative endonuclease/exonuclease/phosphatase family protein BF0973 5 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 60682011 Common - hypothetical protein BF2531 72 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 60682390 Common - putative SAM-dependent methyltransferase BF2920 28 COG3129 COG3129, Predicted SAM-dependent methyltransferase General function prediction only 60682431 Common - hypothetical protein BF2961 29 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 60682655 Common - putative Na/H exchanger membrane protein BF3186 176 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 60681820 Common fsr putative fosmidomycin resistance protein BF2342 78 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60682199 Common prfH peptide chain release factor-like protein BF2726 215 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 60683592 Common - hypothetical protein BF4171 13 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60680571 Common - conserved hypothetical lipoprotein BF1028 2 None None None 60681280 Pathogen - hypothetical protein BF1788 1 None None None 60683291 Pathogen - hypothetical protein BF3848 1 None None None 60680458 Common - putative helicase protein BF0909 90 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 60681474 Common - putative outer membrane protein BF1986 118 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682932 Pathogen - hypothetical protein BF3472 2 None None None 60680460 Common - putative aminotransferase BF0911 231 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 60683087 Pathogen - hypothetical protein BF3637 1 None None None 60679849 Common murD putative UDP-N-acetylmuramoylalanine--D-glutamate ligase BF0256 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 60680290 Common - putative DegT/DnrJ/EryC1/StrS aminotransferase family O-antigen related protein BF0734 197 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 60680147 Common - putative AraC family transcriptional regulatory protein BF0581 96 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60683315 Pathogen - hypothetical protein BF3878 2 None None None 60682701 Pathogen - hypothetical protein BF3232 1 None None None 60679703 Pathogen - hypothetical protein BF0107 1 None None None 60681815 Common - hypothetical protein BF2337 34 COG5587 COG5587, Uncharacterized conserved protein Function unknown 60680990 Common - putative conserved protein found in conjugate transposon BF1488 15 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 60680790 Pathogen - hypothetical protein BF1271 1 None None None 60681108 Common ndh putative NADH dehydrogenase, FAD-containing subunit BF1612 167 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 60683046 Common - hypothetical protein BF3595 12 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 60680113 Common ribA putative riboflavin biosynthesis protein [includes: GTP cyclohydrolase ii; 3,4-dihydroxy-2-butanone 4-phosphate synthase (dhbp synthase)] BF0544 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 60683587 Common - possible xylosidase/arabinosidase BF4166 29 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 60679600 Pathogen - hypothetical protein BF0003 2 None None None 60679791 Common - arginine decarboxylase BF0196 149 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 60680830 Pathogen - possible endo-beta-N-acetylglucosaminidase BF1312 1 None None None 60680890 Common wcfR putative DegT/DnrJ/EryC1/StrS family amino sugar synthetase BF1376 196 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 60680021 Common proB gamma-glutamyl kinase BF0444 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 60681222 Pathogen - hypothetical protein BF1730 2 None None None 60681093 Common - possible histidinol-phosphatase BF1597 40 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 60682321 Common - conserved hypothetical translation inhibitor protein BF2851 190 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 60681022 Common mobB mobilisation protein B BF1521 3 None None None 60680317 Pathogen - hypothetical protein BF0762 1 None None None 60682728 Common - hypothetical protein BF3258 12 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60682706 Common - conserved exported protein BF3237 108 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 60682994 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase BF3536 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 60681696 Common - putative hydrolase BF2217 123 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 60680548 Pathogen - hypothetical protein BF1004 3 None None None 60681289 Common - putative outer membrane protein BF1797 5 None None None 60679774 Common acpP putative acyl carrier protein BF0179 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 60683564 Common - putative DNA-binding protein BF4143 51 COG3655 COG3655, Predicted transcriptional regulator Transcription 60681728 Common - putative rhamnose biosynthesis-related protein BF2249 181 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 60680603 Common - putative ATP/GTP-binding protein BF1066 22 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 60681246 Common - hypothetical protein BF1754 3 None None None 60680352 Pathogen - putative transmembrane protein BF0800 1 None None None 60681688 Common - conserved hypothetical lipoprotein BF2209 9 COG1409 Icc, Predicted phosphohydrolases General function prediction only 60682748 Pathogen - hypothetical protein BF3280 3 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 60680564 Common wcfG putative glycosyltransferase BF1021 20 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60683016 Common - putative isomerase BF3558 128 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 60680551 Common - putative methyltransferase BF1007 139 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 60679990 Pathogen - hypothetical protein BF0409 1 None None None 60682422 Common - putative N-acetylglucosamine-6-phosphate deacetylase BF2952 120 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 60682474 Pathogen - hypothetical protein BF3004 1 None None None 60680874 Pathogen - hypothetical protein BF1358 1 None None None 60680539 Common - hypothetical protein BF0995 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 60682638 Common - hypothetical protein BF3169 14 None None None 60680591 Common - putative AraC-family transcriptional regulator BF1052 91 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60680641 Pathogen - hypothetical protein BF1111 1 None None None 60681121 Common - putative biotin-requiring enzyme BF1625 179 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 60680530 Common - putative alkaline phosphatase BF0984 17 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60681732 Common - putative two component system sensor histidine kinase BF2253 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60682998 Common - putative membrane dehydrogenase protein BF3540 5 None None None 60679819 Common - putative aminotransferase BF0225 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 60682949 Pathogen - hypothetical protein BF3490 2 None None None 60680673 Common - hypothetical protein BF1147 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 60682312 Common - putative anti sigma factor BF2842 30 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 60681229 Common - hypothetical protein BF1737 3 None None None 60683710 Common - putative O-antigen repeat unit transporter BF4298 104 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 60681029 Common satG putative acetyltransferase BF1528 165 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 60680841 Common pflB putative formate acetyltransferase 1 BF1323 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 60681262 Common traJ conserved transmembrane protein found in conjugative transposon BF1770 4 None None None 60680923 Common - putative RNA polymerase ECF-type sigma factor BF1412 101 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60680544 Common - hypothetical protein BF1000 5 None None None 60682425 Common - hypothetical protein BF2955 4 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 60681462 Pathogen - hypothetical protein BF1974 3 None None None 60681606 Common - putative aldo/keto reductase BF2125 196 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 60680510 Common - hypothetical protein BF0963 5 None None None 60682804 Common accC2 putative biotin carboxylase 2 BF3337 237 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 60683297 Common - putative regulatory protein BF3855 40 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60680584 Common - possible transglutaminase-family protein BF1045 7 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 60682294 Pathogen - hypothetical protein BF2823 1 None None None 60680902 Common - hypothetical protein BF1388 8 None None None 60682971 Common - putative puter membrane protein BF3513 17 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60680843 Pathogen - hypothetical protein BF1325 1 None None None 60679986 Common - hypothetical protein BF0403 7 None None None 60680948 Common - putative ABC transporter permease component BF1439 11 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60682732 Common - putative glycosyl transferase BF3262 164 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60683231 Common rpsI 30S ribosomal protein S9 BF3786 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 60681961 Common - putative DNA-binding protein BF2481 7 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 60679860 Common - hypothetical protein BF0267 68 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60679984 Pathogen - putative transmembrane protein BF0401 1 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 60680828 Common - putative outer membrane protein BF1310 11 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60683290 Pathogen - hypothetical protein BF3847 1 None None None 60679923 Common - hypothetical protein BF0334 22 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680776 Pathogen - hypothetical protein BF1256 1 None None None 60682686 Common poxB putative pyruvate dehydrogenase [cytochrome] BF3217 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 60680443 Common - putative outer membrane receptor protein BF0893 9 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60683628 Pathogen - hypothetical protein BF4208 2 None None None 60681716 Common - putative thioredoxin BF2237 228 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 60680467 Common - putative transmembrane protein BF0918 32 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 60680666 Common - hypothetical protein BF1140 72 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 60680694 Common - putative dephospho-CoA kinase BF1169 132 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 60681448 Common - putative outer membrane protein OmpA-family BF1959 54 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60682607 Common fba fructose-bisphosphate aldolase BF3138 176 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 60682928 Pathogen - hypothetical protein BF3468 1 None None None 60683239 Common maa putative maltose O-acetyltransferase BF3794 204 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 60681774 Pathogen - hypothetical protein BF2296 1 None None None 60679737 Pathogen - possible acetyltransferase protein BF0141 8 COG0456 RimI, Acetyltransferases General function prediction only 60679899 Pathogen - hypothetical lipoprotein BF0310 2 None None None 60681163 Common - putative short-chain dehydrogenase BF1669 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 60682095 Common rnfG electron transport complex protein RnfG BF2616 61 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 60680856 Pathogen - hypothetical protein BF1340 1 None None None 60681926 Pathogen - hypothetical protein BF2445 1 None None None 60682419 Common - hypothetical protein BF2949 4 None None None 60680940 Common - putative permease component of ABC transporter BF1431 20 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60682842 Common - hypothetical protein BF3380 31 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 60680943 Pathogen - putative ABC transporter permease component BF1434 3 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60680370 Pathogen - hypothetical protein BF0818 1 None None None 60682794 Pathogen - putative lipoprotein BF3326 2 None None None 60683680 Common - putative two-component sensor histidine kinase with PAS domain BF4262 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60681938 Common - hypothetical protein BF2458 6 COG4652 COG4652, Uncharacterized protein conserved in bacteria Function unknown 60682723 Pathogen - hypothetical protein BF3254 1 None None None 60681929 Common - putative two component system histidine kinase BF2449 222 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 60682273 Pathogen - putative acyltransferase transmembrane protein BF2802 1 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 60682765 Common - hypothetical protein BF3297 49 COG0546 Gph, Predicted phosphatases General function prediction only 60683767 Common - putative transmembrane cation efflux protein BF4356 181 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 60683635 Common - putative TPR-repeat protein BF4215 90 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 60680104 Common frrF putative anti-sigma factor BF0535 32 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60681794 Common - hypothetical protein BF2316 4 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60681958 Common - hypothetical protein BF2478 9 None None None 60682648 Pathogen - hypothetical DNA-binding protein BF3179 1 None None None 60679719 Pathogen - hypothetical protein BF0123 1 None None None 60679731 Common - hypothetical protein BF0135 50 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 60679659 Pathogen - hypothetical protein BF0063 2 None None None 60680974 Common - hypothetical protein BF1471 5 None None None 60681541 Common - putative capsular polysaccharide glycosyltransferase BF2056 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60679906 Common - putative exported carbohydrate-binding protein BF0317 28 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 60682787 Pathogen - hypothetical protein BF3319 1 None None None 60682528 Common - hypothetical protein BF3059 61 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 60682049 Common - putative RNA pseudouridylate synthase BF2569 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 60683780 Common mutS DNA mismatch repair protein BF4369 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 60680691 Common - putative N utilization substance protein BF1166 72 COG0781 NusB, Transcription termination factor Transcription 60681962 Common pyrK putative dihydroorotate dehydrogenase electron transfer subunit BF2482 119 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 60682552 Common - putative exported fucosidase BF3083 27 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 60682110 Common - putative acetyltransferase BF2631 31 COG0456 RimI, Acetyltransferases General function prediction only 60682181 Common - putative exported TonB-dependent receptor protein BF2708 129 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60682368 Common - putative regulatory protein BF2898 87 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 60683420 Common rpmD 50S ribosomal protein L30 BF3985 118 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 60680984 Pathogen - hypothetical protein BF1482 1 None None None 60682437 Common - putative 5-methyltetrahydrofolate--homocysteine methyltransferase BF2967 135 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 60682139 Common - hypothetical protein BF2663 3 COG3577 COG3577, Predicted aspartyl protease General function prediction only 60683403 Common hutI putative imidazolonepropionase BF3968 98 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 60683476 Pathogen - hypothetical protein BF4042 1 None None None 60683713 Common - putative glycosyltransferase BF4301 196 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60680066 Common - putative mismatch repair-like protein BF0496 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 60683142 Common - putative haloacid dehalogenase-like hydrolase BF3696 191 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 60681490 Pathogen - hypothetical protein BF2002 1 None None None 60682403 Common - hypothetical protein BF2933 12 None None None 60682805 Common - putative bioin-requiring protein BF3338 155 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 60682813 Common - putative transport-related, exported protein BF3348 161 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60683062 Pathogen - hypothetical protein BF3612 1 None None None 60680699 Common - putative transcriptional regulator BF1174 193 COG0583 LysR, Transcriptional regulator Transcription 60680195 Common - hypothetical protein BF0633 38 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 60682246 Common - hypothetical protein BF2774 48 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 60682379 Pathogen - hypothetical protein BF2909 1 None None None 60683429 Common rpsQ 30S ribosomal protein S17 BF3994 235 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 60679738 Common uxuA mannonate dehydratase BF0142 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 60680438 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein BF0887 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 60681486 Pathogen - hypothetical protein BF1998 1 None None None 60681173 Pathogen - hypothetical protein BF1679 2 None None None 60682256 Common - putative N-acetylmuramoyl-L-alanine amidase BF2785 17 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 60679688 Common - putative metal ABC transporter substrate-binding precursor BF0092 159 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 60680048 Pathogen - hypothetical protein BF0475 1 None None None 60683078 Common - putative long-chain-fatty-acid--CoA ligase BF3628 217 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 60681866 Common rkpK UDP-glucose 6-dehydrogenase BF2386 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 60683652 Pathogen - hypothetical protein BF4232 3 None None None 60682847 Common - hypothetical protein BF3385 3 None None None 60683028 Common - putative anti sigma factor BF3573 35 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60683705 Common - hypothetical protein BF4290 3 None None None 60681830 Common sucD succinyl-CoA synthetase alpha chain BF2350 214 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 60680730 Common - possible phosphodiesterase/nucleotide pyrophosphatase-like protein BF1207 19 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 60682441 Common - putative lipoprotein BF2971 3 None None None 60682079 Common rfbE DNTP-hexose dehydratase-epimerase BF2600 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60682264 Common - hypothetical protein BF2793 5 COG1035 FrhB, Coenzyme F420-reducing hydrogenase, beta subunit Energy production and conversion 60682890 Pathogen - hypothetical protein BF3428 1 None None None 60683225 Common ispF putative 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase BF3780 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 60680663 Common - putative transposase BF1137 4 None None None 60682010 Common - hypothetical protein BF2530 111 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 60680326 Common - hypothetical protein BF0772 26 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 60680360 Common - putative two-component system sensor histidine kinase/response regulator fusion protein BF0808 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60682157 Common - putative sugar transferase-related membrane protein BF2683 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 60682679 Common - hypothetical protein BF3210 16 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 60683050 Common - hypothetical protein BF3599 125 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 60680601 Pathogen - hypothetical protein BF1062 1 None None None 60680740 Common - putative transmembrane magnesium and cobalt transporter protein BF1217 170 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 60682713 Common - putative iron storage-related regulatory protein BF3244 142 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 60682683 Common - putative RNA polymerase sigma factor BF3214 162 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60683180 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase BF3735 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 60683092 Common - putative transmembrane sensor/regulatory protein BF3641 40 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60682359 Common hisF imidazole glycerol phosphate synthase subunit BF2889 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 60681805 Pathogen - putative lipoprotein BF2327 2 None None None 60680959 Common - putative transmembrane protein BF1454 4 None None None 60679765 Common mgtA putative Mg2+ transport ATPase protein BF0170 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 60681250 Common - putative transmembrane TraG/TraD family mobilization protein BF1758 15 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 60682486 Common - putative thioredoxin family protein BF3016 226 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 60681559 Common - putative peptidyl-prolyl cis-trans isomerase BF2075 131 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 60682516 Common - hypothetical protein BF3046 6 None None None 60681493 Pathogen - hypothetical protein BF2005 1 None None None 60683172 Common folE GTP cyclohydrolase I BF3727 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 60679782 Common - putative glycosyltransferase BF0187 217 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60680496 Common - putative 3'-5' exonuclease BF0948 22 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 60679654 Pathogen - hypothetical protein BF0058 2 None None None 60679972 Common - putative ABC transporter ATP-binding protein BF0387 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 60681344 Pathogen - hypothetical protein BF1853 1 None None None 60681855 Common - hypothetical protein BF2375 7 None None None 60680950 Common - hypothetical protein BF1444 10 None None None 60682496 Common - hypothetical protein BF3026 9 COG1409 Icc, Predicted phosphohydrolases General function prediction only 60682943 Pathogen - hypothetical protein BF3483 1 None None None 60682204 Common rpsP 30S ribosomal protein S16 BF2731 212 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 60681781 Pathogen - hypothetical protein BF2303 1 None None None 60683685 Common - hypothetical protein BF4267 3 None None None 60683287 Pathogen - hypothetical protein BF3844 1 None None None 60681104 Common - putative HlyD-family transporter component BF1608 123 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 60679816 Pathogen - hypothetical protein BF0222 1 None None None 60682672 Common - putative electron transfer flavoprotein alpha-subunit BF3203 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 60681951 Common - hypothetical protein BF2471 20 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 60682288 Common - putative nucleotidyltransferase BF2817 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 60680161 Common - hypothetical protein BF0595 7 None None None 60681196 Common - putative indolepyruvate oxidoreductase/indolepyruvate ferredoxin oxidoreductase BF1702 107 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 60683241 Common - putative exported hyaluronidase BF3796 15 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60681678 Common - hypothetical protein BF2199 18 None None None 60683533 Common lacA putative thiogalactoside transacetylase BF4109 191 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 60682530 Common - hypothetical protein BF3061 4 None None None 60680301 Common - putative transposase_11 DDE family protein BF0746 5 None None None 60680570 Pathogen - putative iron-regulated transmembrane protein BF1027 1 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 60682625 Common - putative chromate transport protein BF3156 116 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 60681846 Common - hypothetical protein BF2366 5 None None None 60682858 Common - hypothetical protein BF3396 28 COG1556 COG1556, Uncharacterized conserved protein Function unknown 60681210 Common - hypothetical protein BF1718 6 None None None 60681322 Pathogen - hypothetical protein BF1830 1 None None None 60681904 Pathogen - hypothetical protein BF2425 2 None None None 60682036 Common sodB superoxide dismutase [Fe] BF2556 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 60682537 Common - hypothetical protein BF3068 9 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60680558 Common wcfB putative fucosyl transferase BF1015 19 None None None 60680765 Common - conserved hypothetical protein found in conjugate transposon BF1245 4 None None None 60681994 Common - hypothetical protein BF2514 42 COG3304 COG3304, Predicted membrane protein Function unknown 60680262 Common - hypothetical protein BF0703 195 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 60680393 Pathogen - hypothetical protein BF0842 2 None None None 60681111 Common - putative biotin synthesis-related fusion protein BF1615 63 COG2830 COG2830, Uncharacterized protein conserved in bacteria Function unknown 60683127 Pathogen - putative non-specific DNA-binding protein BF3679 2 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60683616 Common - hypothetical protein BF4195 186 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 60681508 Pathogen - hypothetical protein BF2020 1 None None None 60683276 Pathogen - hypothetical protein BF3833 1 None None None 60682915 Common - putative LPS biosynthesis related glycosyltransferase BF3454 92 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60679952 Common - hypothetical protein BF0364 5 None None None 60682411 Common - hypothetical protein BF2941 6 None None None 60681353 Pathogen - hypothetical protein BF1862 2 None None None 60683341 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III BF3904 230 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 60683371 Pathogen - hypothetical protein BF3934 1 None None None 60682560 Common gpmA phosphoglyceromutase BF3091 164 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 60681857 Pathogen - hypothetical protein BF2377 2 None None None 60680171 Common - putative outer membrane protein BF0606 98 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60680870 Pathogen - hypothetical protein BF1354 1 None None None 60682721 Common - putative membrane attached sulfatase protein BF3252 54 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 60682122 Common - putative transport-related membrane protein BF2643 42 COG2949 SanA, Uncharacterized membrane protein Function unknown 60683515 Common - putative O-antigen related protein BF4091 7 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 60683548 Common greA putative transcription elongation factor BF4127 204 COG0782 GreA, Transcription elongation factor Transcription 60682113 Common uvrA1 UvrABC SOS-repair system protein excinuclease A BF2634 241 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 60680701 Pathogen - hypothetical protein BF1176 2 None None None 60683755 Common - putative TonB-dependent outer membrane receptor protein BF4344 84 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682125 Common - putative two-component system sensor kinase/response regulator fusion protein BF2647 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60681588 Pathogen - putative transmembrane protein BF2107 1 None None None 60682150 Common trpD anthranilate phosphoribosyltransferase BF2675 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 60682861 Common - hypothetical protein BF3399 172 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 60681381 Pathogen - hypothetical protein BF1891 1 None None None 60683469 Common - putative transmembrane protein BF4035 4 None None None 60683169 Common - hypothetical protein BF3724 8 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60682329 Pathogen - putative conserved exported protein BF2859 1 None None None 60683081 Common rpsR 30S ribosomal protein S18 BF3631 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 60681703 Common - hypothetical protein BF2224 9 None None None 60681445 Common - putative outer membrane protein BF1956 14 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60682085 Common upeY putative transcriptional regulatory protein BF2606 3 COG0250 NusG, Transcription antiterminator Transcription 60681405 Pathogen - hypothetical protein BF1915 1 None None None 60681564 Common - putative metallo-beta-lactamase BF2080 221 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 60680342 Common nuoI putative NADH dehydrogenase I subunit I BF0788 176 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 60682904 Pathogen - putative lipoprotein BF3443 3 None None None 60682503 Common - putative exported cytochrome C biogenesis-related protein BF3033 101 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 60681482 Common - hypothetical protein BF1994 2 None None None 60682171 Pathogen - hypothetical protein BF2698 3 None None None 60681628 Common - putative aldo/keto reductase BF2149 199 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 60681061 Common - putative glycosyltransferase BF1560 143 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60680241 Common - putative alpha-1,2-mannosidase precursor BF0682 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 60681479 Common - putative TonB-dependent outer membrane receptor protein BF1991 84 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 60682573 Common pheS phenylalanyl-tRNA synthetase subunit alpha BF3104 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 60680839 Pathogen - hypothetical protein BF1321 2 None None None 60679998 Common - putative transmembrane holin-like protein LrgA BF0418 21 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 60681910 Pathogen - hypothetical protein BF2431 1 None None None 60681973 Common gyrA DNA gyrase A subunit BF2493 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 60683352 Common - putative rod shape-determining protein MreC BF3915 55 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 60683484 Common - putative outer membrane protein BF4056 15 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60681991 Common - putative competence-damage inducible BF2511 213 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 60682961 Common - putative prenyltransferase BF3503 104 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 60679841 Common - possible DNA repair protein RecO BF0248 8 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 60681372 Common - putative transmembrane transport efflux protein BF1882 155 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60679709 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA BF0113 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 60683486 Common - putative endo-beta-galactosidase BF4058 47 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 60680475 Common - putative bifunctional 2-polyprenylphenol hydroxylase/glutamate synthase subunit beta BF0926 228 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 60682213 Pathogen - hypothetical protein BF2740 1 None None None 60681756 Common - putative peptidase BF2278 165 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 60679702 Common - hypothetical protein BF0106 3 None None None 60680779 Pathogen - hypothetical protein BF1259 3 None None None 60682563 Common - putative sulfatase BF3094 88 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60680968 Pathogen - hypothetical protein BF1465 1 None None None 60683698 Common - hypothetical protein BF4283 3 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 60683303 Common - pyridoxamine kinase BF3861 58 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 60683034 Common - hypothetical protein BF3581 9 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60681424 Common - putative HlyD family secretion protein BF1935 171 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60680334 Common - hypothetical protein BF0780 23 None None None 60681539 Common - hypothetical protein BF2054 10 None None None 60683542 Pathogen - hypothetical protein BF4118 1 None None None 60679712 Pathogen - hypothetical protein BF0116 2 None None None 60680201 Common - phosphatidylserine decarboxylase BF0640 91 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 60683322 Common mutL putative DNA mismatch repair protein BF3885 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 60683695 Common - hypothetical protein BF4280 6 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 60680816 Pathogen - hypothetical protein BF1298 1 None None None 60681217 Pathogen - hypothetical protein BF1725 1 None None None 60681763 Common - hypothetical protein BF2285 14 None None None 60683579 Pathogen - hypothetical protein BF4157 2 None None None 60682278 Common - putative glycosyltransferase protein BF2807 117 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60680208 Common - hypothetical protein BF0649 3 None None None 60680720 Common katA catalase BF1195 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 60680253 Common - hypothetical protein BF0694 7 None None None 60682695 Pathogen - putative lipoprotein BF3226 1 None None None 60683444 Pathogen - hypothetical protein BF4009 1 None None None 60681208 Common - putative major facilitator superfamily transporter BF1714 180 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 60680088 Common - hypothetical protein BF0519 4 None None None 60682985 Common - hypothetical protein BF3527 5 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 60680051 Common - putative pyrroline-5-carboxylate reductase BF0478 215 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 60681426 Common cydA putative cytochrome d ubiquinol oxidase subunit I BF1937 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 60681652 Common - putative two-component regulatory system histidine kinase BF2173 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60681919 Pathogen - hypothetical protein BF2439A 1 None None None 60682145 Common - putative phosphatase BF2669 181 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 60682384 Pathogen - hypothetical protein BF2915 1 None None None 60683761 Common - putative thioesterase protein BF4350 23 COG0824 FcbC, Predicted thioesterase General function prediction only 60680623 Pathogen - hypothetical protein BF1091 1 None None None 60683261 Common - hypothetical protein BF3817 4 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60680271 Pathogen - hypothetical protein BF0712 2 None None None 60682582 Pathogen - hypothetical protein BF3113 1 None None None 60681552 Common nqrD Na(+)-translocating NADH-quinone reductase subunit D BF2068 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 60680934 Common - putative transmembrane protein BF1425 26 COG3059 COG3059, Predicted membrane protein Function unknown 60681985 Common - hypothetical protein BF2505 14 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60682350 Common - hypothetical protein BF2880 12 None None None 60681943 Common aspS aspartyl-tRNA synthetase BF2463 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60682360 Common hisA imidazole-4-carboxamide isomerase BF2890 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 60680175 Common - putative ATP-binding transporter component BF0610 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 60683201 Common - hypothetical protein BF3755 36 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60680789 Common - putative AraC-family transcriptional regulatory protein BF1270 98 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60681671 Common - putative helicase BF2192 145 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 60680013 Common ddl D-alanyl-alanine synthetase A BF0435 218 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 60683113 Common thiH thiamine biosynthesis protein ThiH BF3664 58 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 60680033 Pathogen - putative conserved hypothetical protein BF0456 3 None None None 60683234 Pathogen - hypothetical protein BF3789 1 None None None 60682605 Common - putative HlyD-family secretion protein BF3136 165 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 60683253 Common trpS tryptophanyl-tRNA synthetase II BF3809 248 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60680211 Common - putative transmembrane protein BF0652 97 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 60682105 Common - putative transpor-related membrane protein BF2626 104 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60682305 Pathogen - hypothetical protein BF2835 1 None None None 60681888 Common - hypothetical protein BF2409 5 None None None 60681893 Pathogen - hypothetical protein BF2414 1 None None None 60682555 Common - putative exported sulfatase BF3086 94 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60680418 Common - possible outer membrane protein BF0867 6 None None None 60679918 Common - putative exported beta-hexosaminidase BF0329 56 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60682589 Common maf Maf-like protein BF3120 192 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 60683602 Common pflD putative formate acetyltransferase (pyruvate formate-lyase) BF4181 58 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 60681577 Common - putative two-component response regulator transcriptional regulatory protein BF2095 209 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 60683248 Pathogen aapB hypothetical protein BF3803 1 None None None 60681233 Pathogen - hypothetical protein BF1741 1 None None None 60682645 Common - putative sugar transport-related, membrane protein BF3176 113 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 60679676 Common - putative peptidase/protease family protein BF0080 156 COG4946 COG4946, Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system Function unknown 60679938 Common - putative outer membrane protein BF0350 6 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 60681988 Common ftsY putative recognition particle-docking protein BF2508 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 60683743 Common - putative transmembrane K+ dependent Na+/Ca+ exchanger-related protein BF4331 113 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 60680650 Common - putative DNA-binding protein BF1121 62 COG3943 COG3943, Virulence protein General function prediction only 60682580 Common - hypothetical protein BF3111 53 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 60679836 Common - putative two-component sensor histidine kinase BF0243 125 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60681617 Common - possible carboxymuconolactone decarboxylase BF2138 96 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 60680120 Common - putative TonB dependent receptor BF0551 109 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682628 Common uvrA2 UvrABC SOS-repair system protein excinuclease A BF3159 240 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 60679803 Pathogen - hypothetical protein BF0208 1 None None None 60683323 Pathogen - hypothetical protein BF3886 3 None None None 60682707 Common hisS histidyl-tRNA synthetase BF3238 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60683557 Pathogen - hypothetical protein BF4136 3 None None None 60682317 Pathogen - hypothetical protein BF2847 1 None None None 60682719 Common - putative TPR repeat domain exported protein BF3250 97 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 60683044 Common mutA putative methylmalonyl-CoA mutase small subunit BF3593 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 60681729 Pathogen - hypothetical protein BF2250 1 None None None 60683373 Common - putative ABC transporter transmembrane component BF3936 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 60683346 Common - putative DNA polymerase III delta prime subunit BF3909 185 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 60679598 Common - putative SpoU rRNA methylase family protein BF0001 216 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 60681751 Pathogen - hypothetical protein BF2272 2 None None None 60682974 Pathogen - hypothetical protein BF3516 1 None None None 60683453 Common rplA 50S ribosomal protein L1 BF4018 241 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 60682584 Common - putative non ribosome peptide synthase related, AMP-binding protein BF3115 221 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 60680588 Pathogen - hypothetical protein BF1049 1 None None None 60680811 Common - putative Na+/H+ family transporter BF1293 208 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 60681321 Pathogen - putative transmembrane protein BF1829 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 60682327 Common - putative DNA polymerase III beta chain BF2857 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 60682642 Common - conserved DNA methyltransferase protein BF3173 164 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 60679628 Pathogen - hypothetical protein BF0031 2 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 60683474 Common - hypothetical protein BF4040 4 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 60683607 Common - possible amidophosphoribosyl-transferase BF4186 162 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 60680177 Pathogen - hypothetical protein BF0612 1 None None None 60680186 Common dnaK1 putative chaperone protein BF0623 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 60681894 Pathogen - hypothetical protein BF2415 1 None None None 60683456 Common secE putative preprotein translocase SecE subunit BF4021 4 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 60683730 Pathogen - hypothetical protein BF4318 1 None None None 60683708 Pathogen - hypothetical protein BF4296 2 None None None 60683639 Common argS arginyl-tRNA synthetase BF4219 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60680182 Common frr ribosome recycling factor BF0619 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 60682460 Pathogen - putative lipoprotein BF2990 1 None None None 60682615 Common - hypothetical protein BF3146 35 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60682297 Common - dihydroorotate dehydrogenase 2 BF2826 83 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 60680531 Common - putative transmembrane protein BF0985 8 None None None 60680511 Common mazG nucleoside triphosphate pyrophosphohydrolase BF0964 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 60680445 Common - hypothetical protein BF0895 6 None None None 60683753 Common - putative iron-regulated transmembrane protein BF4342 64 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 60680417 Common - putative outer membrane protein BF0866 25 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60682565 Common - putative lipoprotein BF3096 4 None None None 60681702 Common relA GTP pyrophosphokinase BF2223 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 60682556 Common - putative exported sulfatase BF3087 90 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60679911 Pathogen - hypothetical membrane protein BF0322 1 None None None 60682772 Common - hypothetical protein BF3304 9 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 60683088 Pathogen - hypothetical protein BF3637A 1 None None None 60680062 Pathogen - hypothetical protein BF0492 1 None None None 60680629 Pathogen - hypothetical protein BF1098 1 None None None 60681328 Common - hypothetical protein BF1837 49 COG3472 COG3472, Uncharacterized conserved protein Function unknown 60680340 Common nuoK putative NADH dehydrogenase chain K BF0786 82 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 60682084 Pathogen upeZ putative transcriptional regulatory protein BF2605 1 None None None 60680477 Common serS seryl-tRNA synthetase BF0928 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 60680025 Common ompH putative cationic 19 kDa outer membrane protein precursor BF0448 43 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 60681944 Common - hypothetical protein BF2464 10 COG2246 COG2246, Predicted membrane protein Function unknown 60680679 Pathogen - putative transmembrane protein BF1153 3 None None None 60682447 Common - hypothetical protein BF2977 109 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 60680859 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase BF1343 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 60680336 Common - putative two-component system sensor histidine kinase BF0782 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60683235 Common asnC asparaginyl-tRNA synthetase BF3790 169 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 60679875 Common - hypothetical protein BF0282 28 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 60680665 Common - putative two-component system sensor histidine kinase/response regulator fusion protein BF1139 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60680403 Common - putative transmembrane protein BF0852 77 COG1284 COG1284, Uncharacterized conserved protein Function unknown 60682606 Common - putative transport-related membrane protein BF3137 11 None None None 60679979 Common glsA glutaminase BF0394 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 60682280 Pathogen - hypothetical protein BF2809 4 None None None 60681674 Common - hypothetical protein BF2195 8 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60683162 Common - putative chorismate mutase BF3717 130 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 60681538 Common - putative glycosyltransferase BF2053 9 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60682524 Common - putative antiporter membrane protein BF3055 124 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60683437 Common rplD 50S ribosomal protein L4 BF4002 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 60679632 Pathogen - hypothetical protein BF0035 1 None None None 60682531 Common - hypothetical protein BF3062 3 None None None 60679736 Pathogen - hypothetical protein BF0140 1 None None None 60681197 Common - putative aminodeoxychorismate lyase BF1703 183 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 60679618 Common nadB putative exported L-aspartate oxidase BF0021 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 60681026 Pathogen - hypothetical protein BF1525 1 None None None 60683536 Common - hypothetical protein BF4112 8 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 60680439 Pathogen - hypothetical protein BF0888 1 None None None 60682186 Common - ribonucleotide-diphosphate reductase subunit alpha BF2713 216 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 60681134 Pathogen - hypothetical protein BF1640 3 None None None 60682940 Common ruvA Holliday junction DNA helicase motor protein BF3480 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 60680967 Pathogen - hypothetical protein BF1464 1 None None None 60681077 Pathogen - hypothetical protein BF1578 1 None None None 60680265 Common ksgA dimethyladenosine transferase BF0706 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 60682261 Common - putative transcriptional regulator (pseudogene) BF2790 21 COG0250 NusG, Transcription antiterminator Transcription 60680035 Common - putative bacteriophage resolvase/recombinase BF0458 49 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 60683575 Common - putative two-component regulator sensor histidine kinase transcriptional regulator BF4153 205 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60682652 Common - putative nitroreductase family protein BF3183 67 COG0778 NfnB, Nitroreductase Energy production and conversion 60682878 Pathogen - hypothetical protein BF3416 1 None None None 60682198 Common - hypothetical protein BF2725 7 None None None 60683254 Common ompA putative major outer membrane protein BF3810 42 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60682355 Common - putative diaminopimelate decarboxylase BF2885 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 60682290 Common - putative Na+ transport decarboxylase membrane protein BF2819 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 60680773 Common - hypothetical protein BF1253 3 None None None 60682675 Common - hypothetical protein BF3206 5 None None None 60679939 Common - hypothetical protein BF0351 43 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 60681612 Common - putative aminotransferase BF2133 210 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 60681998 Common cobP bifunctional cobalamin biosynthesis protein BF2518 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 60683627 Pathogen - hypothetical protein BF4207 2 None None None 60679955 Common murQ N-acetylmuramic acid-6-phosphate etherase BF0367 84 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 60682693 Pathogen - putative lipoprotein BF3224 1 None None None 60681399 Common wcgS putative LPS biosynthesis related dehydratase BF1909 192 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60682193 Common - putative LacI-family transcriptional regulator BF2720 122 COG1609 PurR, Transcriptional regulators Transcription 60682659 Common - putative lipoprotein BF3190 21 COG3015 CutF, Uncharacterized lipoprotein NlpE involved in copper resistance Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism 60681478 Pathogen - hypothetical protein BF1990 1 None None None 60681858 Common - hypothetical protein BF2378 19 COG3746 OprP, Phosphate-selective porin Inorganic ion transport and metabolism 60682052 Pathogen - hypothetical protein BF2572 1 None None None 60682328 Common - hypothetical protein BF2858 8 None None None 60681669 Common - putative two component system histidine kinase/response regulator fusion protein BF2190 224 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 60680453 Common - putative flavoprotein BF0904 82 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 60682209 Common - putative ABC transport system, membrane protein BF2736 175 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 60681293 Common - hypothetical protein BF1801 5 None None None 60681358 Pathogen - hypothetical protein BF1867 3 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60681555 Common dbpA putative ATP-independent RNA helicase BF2071 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 60681318 Pathogen - hypothetical protein BF1826 2 None None None 60681151 Common - putative ferredoxin BF1657 100 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 60682534 Pathogen - putative lipoprotein BF3065 1 None None None 60680505 Common - putative reverse transcriptase BF0958 47 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 60681260 Pathogen traH conserved hypothetical protein found in conjugate transposon BF1768 2 None None None 60683061 Common - putative glycosyl hydrolase lipoprotein BF3611 57 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60681801 Pathogen - hypothetical protein BF2323 1 None None None 60681917 Pathogen - hypothetical protein BF2438 1 None None None 60683221 Common - putative tRNA methyltransferase BF3776 213 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 60681527 Common - hypothetical protein BF2041 10 None None None 60682320 Common - putative folylpolyglutamate synthase BF2850 217 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 60683055 Pathogen - putative lipoprotein BF3605 1 None None None 60683696 Common - possible thiol-disulfide oxidoreductase BF4281 34 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60680392 Common - putative phosphate starvation-inducible PhoH-like protein BF0841 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 60682174 Common - hypothetical protein BF2701 117 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 60680338 Common nuoM putative NADH-ubiquinone oxidoreductase subunit BF0784 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 60682124 Common - putative heat-shock related protein BF2646 111 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 60683015 Common - putative AraC-family regulatory protein BF3557 18 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60683479 Common nanH2 putative neuraminidase precursor BF4051 18 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 60682212 Common - putative lipoprotein/thioderoxin BF2739 150 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60682430 Pathogen - hypothetical protein BF2960 2 None None None 60681684 Common - putative regulatory protein BF2205 107 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 60680069 Common - putative glycosyl hydrolase, alpha-xylosidase BF0499 81 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 60682747 Pathogen - hypothetical protein BF3279 1 None None None 60681560 Common - hypothetical protein BF2076 132 COG1739 COG1739, Uncharacterized conserved protein Function unknown 60680470 Common - putative glycosyl hydrolase BF0921 24 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 60680109 Pathogen - hypothetical protein BF0540 2 None None None 60682857 Common - pyridoxamine kinase BF3395 95 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 60682164 Common - hypothetical protein BF2690 9 None None None 60681498 Pathogen - putative transmembrane protein BF2010 1 None None None 60680396 Common - conserved hypothetical protein, possible ATP/GTP-binding site BF0845 3 None None None 60680746 Pathogen - hypothetical protein BF1223 1 None None None 60681865 Common rfbC2 putative LPS biosynthesis related dTDP-4-dehydrorhamnose 3,5-epimerase BF2385 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 60680849 Common - putative alpha-glucosidase II BF1332 81 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 60682827 Pathogen - hypothetical protein BF3363 1 None None None 60681788 Pathogen - hypothetical protein BF2310 1 None None None 60683657 Common porA putative 2-oxoglutarate ferredoxin oxidoreductase subunit BF4239 107 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 60679853 Pathogen - hypothetical protein BF0260 2 None None None 60680153 Common - putative haloacid dehalogenase-like hydrolase protein BF0587 92 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 60682161 Common - hypothetical protein BF2687 4 None None None 60682366 Common - putative regulatory protein BF2896 38 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60679941 Common - DNA topoisomerase IV subunit A BF0353 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 60683711 Common - putative glycosyltransferase BF4299 58 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60682964 Common - putative phosphoesterase BF3506 28 COG0622 COG0622, Predicted phosphoesterase General function prediction only 60679930 Common - putative TonB-dependent outer membrane exported protein BF0341 16 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682356 Common - putative aspartokinase III BF2886 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 60683688 Common - putative lipoprotein releasing system transmembrane protein BF4273 148 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 60681679 Common - hypothetical protein BF2200 15 None None None 60679666 Common - putative S-adenosylmethionine:tRNA ribosyltransferase-isomerase BF0070 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 60682649 Pathogen - hypothetical protein BF3180 1 None None None 60680485 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase BF0936 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 60679942 Common glyS glycyl-tRNA synthetase BF0354 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 60682559 Common fbaB fructose-bisphosphate aldolase BF3090 65 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 60680536 Common - hypothetical protein BF0992 8 None None None 60682716 Common - putative membrane attached peptidase BF3247 13 None None None 60680523 Common - putative TonB-dependent outer membrane receptor protein BF0977 11 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60683785 Common - putative Ham1-like protein BF4374 235 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 60683153 Common - putative transport related, membrane protein BF3708 158 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 60680468 Common - hypothetical protein BF0919 34 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 60679868 Common - putative exported peptidase BF0275 86 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 60680043 Pathogen - hypothetical protein BF0470 1 None None None 60682775 Common - hypothetical protein BF3307 8 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682899 Common - putative peptidase BF3438 228 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 60682389 Common - hypothetical protein BF2919 10 COG3326 COG3326, Predicted membrane protein Function unknown 60683151 Common - putative DEAD box helicase BF3706 228 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 60680766 Common - conserved hypothetical protein found in conjugate transposon BF1246 12 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 60681495 Common - hypothetical protein BF2007 2 None None None 60681504 Pathogen - hypothetical protein BF2016 1 None None None 60681383 Common upbY putative LPS biosynthesis related transcriptional regulatory protein BF1893 3 COG0250 NusG, Transcription antiterminator Transcription 60681567 Pathogen - hypothetical protein BF2083 1 None None None 60682498 Common - putative histidine biosynthesis-related aminotransferase BF3028 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 60680559 Common wcfC putative glycosyltransferase BF1016 34 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60680016 Common - conserved hypothetical rhodanese-domain protein BF0438 133 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 60679763 Common - putative two-component response regulator transcriptional regulatory protein BF0168 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 60681848 Common - putative regulatory protein BF2368 69 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 60682916 Common - putative LPS biosynthesis related glycosyltransferase BF3455 125 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60680099 Common kdpC potassium-transporting ATPase c chain BF0530 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 60680577 Common - hypothetical protein BF1035 32 COG3382 COG3382, Uncharacterized conserved protein Function unknown 60681456 Common - putative histone-like DNA-binding protein BF1967 202 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60681833 Common thiD phosphomethylpyrimidine kinase BF2353 222 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 60680882 Pathogen upaZ putative LPS biosynthesis related transcriptional regulatory protein BF1368 1 None None None 60680693 Common - hypothetical protein BF1168 6 None None None 60682845 Common - hypothetical protein BF3383 73 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 60679679 Common gno gluconate 5-dehydrogenase BF0083 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 60680365 Common - putative transmembrane acyltransferase BF0813 42 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 60681492 Pathogen - hypothetical protein BF2004 1 None None None 60681791 Pathogen - hypothetical protein BF2313 1 None None None 60681995 Common proS prolyl-tRNA synthetase BF2515 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60680552 Common upcY putative transcriptional regulator BF1009 4 COG0250 NusG, Transcription antiterminator Transcription 60680604 Pathogen - hypothetical protein BF1067 1 None None None 60679814 Common - hypothetical protein BF0220 5 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 60679970 Common - putative Na+/H+ antiporter BF0385 200 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 60681236 Pathogen - hypothetical protein BF1744 1 None None None 60683130 Common - putative glycosyltransferase protein BF3684 194 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60680528 Pathogen - hypothetical protein BF0982 2 None None None 60679672 Common rnpA ribonuclease P BF0076 9 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 60682142 Common - L,L-diaminopimelate aminotransferase BF2666 225 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 60680987 Pathogen - hypothetical protein BF1485 1 None None None 60681164 Pathogen - hypothetical protein BF1670 3 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 60683650 Pathogen - hypothetical protein BF4230 1 None None None 60680869 Common - putative transmembrane ferrous transport fusion protein BF1353 178 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 60679967 Common - hypothetical protein BF0381 13 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60683383 Common - hypothetical protein BF3946 6 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 60683510 Pathogen - hypothetical protein BF4086 1 None None None 60682380 Common - putative ECF sigma factor BF2910 77 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60679922 Common - hypothetical protein BF0333 6 None None None 60683052 Common lysS lysyl-tRNA synthetase BF3602 248 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 60682722 Common - hypothetical protein BF3253 35 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 60682922 Common - hypothetical protein BF3461 10 COG2327 WcaK, Uncharacterized conserved protein Function unknown 60682230 Pathogen - conserved exported hypothetical protein BF2758 1 None None None 60680157 Common - putative outer membrane receptor protein BF0591 6 None None None 60680056 Common argR putative arginine repressor BF0483 52 COG1438 ArgR, Arginine repressor Transcription 60683193 Common - putative liporotein BF3747 6 None None None 60682274 Common - putative acetyltransferase BF2803 193 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 60682429 Pathogen - hypothetical protein BF2959 1 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 60683354 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase BF3917 218 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 60679784 Pathogen - hypothetical protein BF0189 3 None None None 60680358 Common - hypothetical protein BF0806 3 None None None 60680426 Common ribH riboflavin synthase subunit beta BF0875 212 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 60681190 Common rpmI 50S ribosomal protein L35 BF1696 164 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 60682031 Common - putative lipoprotein BF2551 5 None None None 60679797 Common - putative lipoprotein BF0202 22 None None None 60681758 Common prs ribose-phosphate pyrophosphokinase BF2280 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 60679683 Common - hypothetical protein BF0087 13 COG1289 COG1289, Predicted membrane protein Function unknown 60683728 Common - putative efflux transporter component BF4316 131 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60683758 Pathogen - hypothetical protein BF4347 2 None None None 60680803 Common - putative outer membrane protein BF1285 57 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60681330 Common - putative type I restriction enzyme, partial BF1839 67 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 60681132 Common prmA ribosomal protein L11 methyltransferase BF1638 176 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 60683090 Common - putative RNA polymerase sigma factor BF3639 101 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60683304 Common dapA1 putative dihydrodipicolinate synthase BF3862 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 60682744 Common punA purine nucleoside phosphorylase BF3274 133 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 60681348 Pathogen - hypothetical protein BF1857 1 None None None 60682799 Common - putative integrase BF3332 12 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60681542 Common - putative capsule-related protein BF2058 15 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60681977 Common batE aerotolerance-related exported protein BF2497 10 COG0457 NrfG, FOG: TPR repeat General function prediction only 60680054 Common argG putative argininosuccinate synthase BF0481 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 60682906 Common - hypothetical protein BF3445 6 None None None 60681183 Common - putative outer membrane protein BF1689 49 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60680079 Common - putative ABC transporter BF0510 195 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60683336 Common - hypothetical protein BF3899 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 60682623 Common - phosphoribosylformylglycinamidine synthase BF3154 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 60681793 Common - hypothetical protein BF2315 2 None None None 60682115 Common - putative conserved exported protein BF2636 5 None None None 60682402 Common - putative AraC-family regulatory protein BF2932 126 COG3449 COG3449, DNA gyrase inhibitor DNA replication, recombination, and repair 60682635 Common - hypothetical protein BF3166 20 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 60680912 Common nadC putative nicotinate-nucleotide pyrophosphorylase [carboxylating] (quinolinate phosphoribosyltransferase [decarboxylating]) BF1400 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 60683206 Common - putative conserved transport-related membrane protein BF3761 56 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 60682006 Pathogen - hypothetical protein BF2526 1 None None None 60682279 Common - putative acetyltransferase/glucosyltransferase BF2808 110 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 60681076 Pathogen - hypothetical protein BF1577 1 None None None 60680731 Common - putative endonuclease/exonuclease/phosphatase family protein BF1208 5 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 60681295 Common - putative outer membrane protein BF1803 19 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60681771 Pathogen - hypothetical protein BF2293 1 None None None 60680653 Common - putative ATP/GTP-binding protein BF1124 105 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 60682626 Common - putative hromate transport membrane protein BF3157 77 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 60679929 Common - hypothetical protein BF0340 6 None None None 60682030 Common - putative bifunctional CbiD/CbiJ cobalamin biosynthesis protein BF2550 82 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 60681601 Pathogen - hypothetical protein BF2120 1 None None None 60682426 Pathogen - hypothetical protein BF2956 1 None None None 60681480 Common - putative outer membrane protein BF1992 10 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60680017 Common - putative ornithine carbamoyltransferase BF0439 226 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 60681521 Pathogen - hypothetical protein BF2035 1 None None None 60679746 Common - hypothetical protein BF0150 197 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 60683027 Common - hypothetical protein BF3572 9 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60681741 Common pyrB aspartate carbamoyltransferase catalytic subunit BF2262 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 60683131 Common - putative glycosyltransferase protein BF3685 78 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60681650 Common - putative transport-related membrane protein BF2171 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 60681918 Pathogen - hypothetical protein BF2439 1 None None None 60679701 Common - putative octaprenyl-diphosphate synthase BF0105 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 60681259 Common traG putative conserved protein found in conjugate transposon BF1767 66 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 60681126 Pathogen - hypothetical protein BF1630 2 None None None 60680212 Pathogen - putative transmembrane protein BF0653 2 None None None 60683192 Common - hypothetical protein BF3746 10 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680850 Pathogen - hypothetical protein BF1333 1 None None None 60683230 Common rpsB 30S ribosomal protein S2 BF3785 218 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 60681365 Common - putative GAF-domain signal transduction protein BF1874 81 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 60682633 Common - putative two-component regulator sensor kinase BF3164 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60680139 Common - putative TonB-linked outer membrane receptor protein BF0571 25 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60681737 Common glyA serine hydroxymethyltransferase BF2258 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 60680831 Common - hypothetical protein BF1313 10 None None None 60681921 Common - hypothetical protein BF2440 2 None None None 60681099 Common - putative transmembrane glycosyltransferase BF1603 26 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60680602 Pathogen - hypothetical protein BF1064 1 None None None 60680784 Common - hypothetical protein BF1265 2 None None None 60682078 Common - putative LPS biosynthesis related glycosyltransferase BF2599 175 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60682158 Pathogen - hypothetical protein BF2684 2 None None None 60682572 Pathogen - hypothetical protein BF3103 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60682343 Pathogen - putative lipoprotein BF2873 1 None None None 60683262 Pathogen - hypothetical protein BF3819 2 None None None 60679645 Pathogen - hypothetical protein BF0048 2 None None None 60683535 Common - putative methylated-DNA--protein-cysteine methyltransferase BF4111 213 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 60680935 Common - putative AraC family transcriptional regulatory protein BF1426 77 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60682973 Common - hypothetical protein BF3515 6 None None None 60681311 Common grpE putative GrpE protein (HSP70 cofactor) BF1819 225 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 60681469 Common - hypothetical protein BF1981 4 None None None 60681656 Pathogen - hypothetical protein BF2177 1 None None None 60683298 Common - putative iron transport, fusion membrane protein BF3856 173 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 60683337 Common - putative ABC amino acid transport system, ATP-binding protein BF3900 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 60683467 Common - hypothetical protein BF4033 5 None None None 60683020 Common - hypothetical protein BF3562 4 None None None 60681682 Common - putative uracil permease BF2203 122 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 60682101 Common - hypothetical protein BF2622 7 None None None 60681117 Pathogen - hypothetical protein BF1621 3 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60681604 Common - putative AraC family transcriptional regulator BF2123 73 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60680624 Pathogen - hypothetical protein BF1092 1 None None None 60679633 Pathogen - hypothetical protein BF0036 1 None None None 60682840 Common - hypothetical protein BF3377 25 COG2378 COG2378, Predicted transcriptional regulator Transcription 60683238 Common - putative exported beta-galactosidase BF3793 24 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 60682745 Common - putative thiamine monophosphate kinase BF3275 190 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 60681773 Pathogen - hypothetical protein BF2295 1 None None None 60681184 Common ruvX Holliday junction resolvase-like protein BF1690 161 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 60680672 Common - hypothetical protein BF1146 162 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 60680705 Common recA recombinase A BF1180 240 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 60683026 Common - hypothetical protein BF3571 4 None None None 60683647 Common - hypothetical protein BF4227 2 None None None 60681333 Common - putative type IC restriction-modification system specificity subunit, partial BF1842 45 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 60680425 Common - putative GFO/IDH/MOCA family oxidoreductase BF0874 81 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 60683739 Common - putative glycosylhydrolase BF4327 53 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 60680949 Common - putative ABC transport system ATP-binding protein BF1443 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 60683590 Common - putative TonB-linked outer membrane protein BF4169 42 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682684 Pathogen - hypothetical protein BF3215 2 None None None 60682937 Common - putative DNa-binding protein BF3477 10 COG1709 COG1709, Predicted transcriptional regulator Transcription 60679867 Pathogen - putative lipoprotein BF0274 2 None None None 60679904 Common - putative transcriptional regulator BF0315 9 COG1609 PurR, Transcriptional regulators Transcription 60683349 Common mrdB putative transmembrane rod shape-determining protein BF3912 205 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 60680612 Common - putative DNA-binding protein BF1076 7 COG1476 COG1476, Predicted transcriptional regulators Transcription 60682291 Common - putative pyruvate carboxylase BF2820 173 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 60682608 Common - hypothetical protein BF3139 20 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 60681896 Pathogen - hypothetical protein BF2417 1 None None None 60681640 Pathogen - hypothetical protein BF2161 1 None None None 60680879 Pathogen - hypothetical protein BF1363 2 None None None 60680411 Common - putative beta-glucosidase BF0860 102 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 60680002 Common ptaA putative phosphate acetyltransferase BF0423 165 COG0280 Pta, Phosphotransacetylase Energy production and conversion 60680119 Pathogen - putative transmembrane protein BF0550 1 None None None 60681928 Pathogen - hypothetical protein BF2448 1 None None None 60683658 Common porB 2-oxoglutarate ferredoxin oxidoreductase subunit beta BF4240 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 60681589 Common - putative acetyltransferase BF2108 66 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 60683036 Common - putative RNA polymerase sigma factor BF3583 41 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60681413 Common - hypothetical protein BF1924 20 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 60683076 Common - putative lipd A biosynthesis related exported protein BF3626 93 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 60681409 Common zwf glucose-6-phosphate 1-dehydrogenase BF1920 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 60680237 Common - hypothetical protein BF0678 4 None None None 60682774 Common - hypothetical protein BF3306 4 None None None 60682507 Common - putative sodium/proline symporter membrane protein BF3037 166 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 60681373 Common - hypothetical protein BF1883 55 COG2985 COG2985, Predicted permease General function prediction only 60681446 Common - hypothetical protein BF1957 5 None None None 60682905 Common - hypothetical protein BF3444 17 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60682834 Common - putative ion transport related, membrane protein BF3371 97 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 60681620 Common - putative acetyltransferase BF2141 104 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 60681611 Common - putative cation efflux protein BF2132 183 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60680692 Common - conserved hypothetical protein with preprotein translocase motif BF1167 162 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 60683082 Common rpsF 30S ribosomal protein S6 BF3632 199 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 60682067 Common - hypothetical protein BF2588 7 None None None 60680242 Common - putative alpha-1,2-mannosidase precursor BF0683 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 60683370 Common - putative TetR-family transcriptional regulator BF3933 64 COG1309 AcrR, Transcriptional regulator Transcription 60683663 Pathogen - hypothetical protein BF4245 1 None None None 60680126 Common thrA putative aspartokinase I-homoserine dehydrogenase BF0558 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 60683673 Common - hypothetical protein BF4255 18 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 60682935 Pathogen - hypothetical protein BF3475 2 None None None 60682378 Common - hypothetical protein BF2908 34 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60681027 Pathogen - hypothetical protein BF1526 1 None None None 60680796 Common - putative SpoU-like rRNA methylase BF1278 216 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 60682546 Common - hypothetical protein BF3077 7 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 60682850 Common - hypothetical protein BF3388 9 None None None 60682026 Common - putative conserved membrane protein BF2546 13 COG4744 COG4744, Uncharacterized conserved protein Function unknown 60683117 Common - putative phosphoglucomutase/phosphomannomutase family protein BF3668 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 60680480 Common - putative haloacid dehalogenase-like hydrolase BF0931 110 COG0546 Gph, Predicted phosphatases General function prediction only 60682281 Pathogen - hypothetical protein BF2810 2 None None None 60681947 Common - hypothetical protein BF2467 14 COG4739 COG4739, Uncharacterized protein containing a ferredoxin domain Function unknown 60682838 Common - hypothetical protein BF3375 38 None None None 60683379 Common - putative TPR-repeat family protein BF3942 42 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 60681824 Common - hypothetical protein BF2346 14 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 60681549 Common nqrA Na(+)-translocating NADH-quinone reductase subunit A BF2065 39 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 60679726 Common - hypothetical protein BF0130 51 COG1808 COG1808, Predicted membrane protein Function unknown 60682410 Pathogen - hypothetical protein BF2940 2 None None None 60682229 Common - putative peptidase BF2757 11 None None None 60682224 Common - putative N-acetylglucosamine-6-phosphate deacetylase BF2752 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 60681425 Common - putative outer membrane lipoprotein precursor BF1936 117 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60680799 Common - putative two-component sensor histidine kinase BF1281 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60681823 Common - putative oxidoreductase BF2345 230 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 60680685 Common - hypothetical protein BF1160 11 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60681165 Common - hypothetical protein BF1671 55 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 60682133 Common - putative thioredoxin BF2656 25 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 60679988 Pathogen - hypothetical protein BF0405 2 None None None 60680082 Common rplS 50S ribosomal protein L19 BF0513 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 60681397 Pathogen wzy putative LPS biosynthesis related polymerase BF1907 1 None None None 60683382 Common - hypothetical protein BF3945 6 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 60679981 Common folP putative dihydropteroate synthase BF0396 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 60680576 Common - hypothetical protein BF1034 178 COG1496 COG1496, Uncharacterized conserved protein Function unknown 60680594 Common - putative acetyltransferase BF1055 70 COG0456 RimI, Acetyltransferases General function prediction only 60682663 Common - putative AraC-family regulatory protein BF3194 96 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60681764 Pathogen - hypothetical protein BF2286 1 None None None 60682335 Common - hypothetical protein BF2865 21 None None None 60682984 Common - putative lipoprotein BF3526 12 None None None 60680100 Common frrB hypothetical protein BF0531 6 None None None 60682021 Common - putative transport-related exported protein BF2541 118 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60683319 Pathogen - hypothetical protein BF3882 1 None None None 60680252 Common - putative lytic murein transglycosylase BF0693 138 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 60683640 Common hup3 putative histone-like DNA-binding protein HU3 BF4220 209 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60680170 Common - putative amino acid transporter BF0604 193 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 60680320 Common - putative beta-glucosidase BF0766 137 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 60681439 Common - hypothetical protein BF1950 3 None None None 60680908 Common - putative ExsB family protein BF1396 176 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 60680314 Common - putative outer membrane protein BF0759 46 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60680495 Common - hypothetical protein BF0947 140 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 60682812 Common - putative AraC-family regulatory protein BF3347 53 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60680277 Common - arginine/ornithine transport system ATPase BF0718 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 60681288 Common - putative alpha-L-fucosidase BF1796 33 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 60682236 Common - putative peptidase BF2764 150 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 60680976 Pathogen - hypothetical protein BF1474 1 None None None 60682394 Common - hypothetical protein BF2924 3 None None None 60682871 Common gdhB2 glutamate dehydrogenase BF3409 167 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 60681631 Pathogen - hypothetical protein BF2152 1 None None None 60683749 Common - putative AraC-family transcriptional regulator BF4337 21 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60681286 Pathogen - hypothetical protein BF1794 3 None None None 60683255 Common - putative hemolysin secretion transport system membrane protein BF3811 74 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 60681811 Pathogen - hypothetical protein BF2332 1 None None None 60680282 Common - putative DNA-binding protein BF0726 13 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 60683567 Pathogen - hypothetical protein (pseudogene) BF4146 1 None None None 60681644 Pathogen - conserved hypothetical lipoprotein BF2165 1 None None None 60683173 Pathogen - hypothetical protein BF3728 3 None None None 60679910 Common - putative peptide chain release factor BF0321 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 60680382 Common - putative orotidine 5'-phosphate decarboxylase BF0831 69 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 60681818 Common - putative oxidoreductase BF2340 180 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 60682266 Common - putative glycosyltransferase protein BF2795 213 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60680958 Common - putative transmembrane protein BF1453 57 COG2985 COG2985, Predicted permease General function prediction only 60682298 Common - putative phage-related protein BF2827 17 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 60680633 Common - conserved hypothetical protein with RecF/RecN/SMC N-terminal domain BF1102 62 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 60682515 Common - hypothetical protein BF3045 6 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 60683312 Pathogen - hypothetical protein BF3873 1 None None None 60680420 Common - putative RNA polymerase ECF-type sigma factor BF0869 34 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60680751 Pathogen - hypothetical protein BF1231 1 None None None 60681734 Common - putative sensor histidine kinase BF2255 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60681950 Pathogen - hypothetical protein BF2470 1 None None None 60682792 Pathogen - hypothetical protein BF3324 1 None None None 60680386 Common - putative LemA family protein BF0835 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 60681847 Common ileS isoleucyl-tRNA synthetase BF2367 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60681889 Pathogen - hypothetical protein BF2410 1 None None None 60680446 Common - hypothetical protein BF0896 143 COG0313 COG0313, Predicted methyltransferases General function prediction only 60682593 Common - putative nitroreductase family protein BF3124 52 COG0778 NfnB, Nitroreductase Energy production and conversion 60680516 Common - putative anti-sigma factor BF0970 28 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60680072 Common - putative anti-sigma factor BF0502 43 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60680162 Common - putative surface membrane protein BF0596 8 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60682487 Common - hypothetical protein BF3017 33 COG0778 NfnB, Nitroreductase Energy production and conversion 60683249 Pathogen aapA putative lipoprotein BF3804 1 None None None 60681012 Common - hypothetical protein BF1510 5 COG5520 COG5520, O-Glycosyl hydrolase Cell envelope biogenesis, outer membrane 60682824 Common - putative chaperone/membrane protein BF3360 124 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 60679696 Common - putative two-component regulator sensor kinase BF0100 97 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 60679770 Common - putative plant auxin-regulated protein BF0175 11 None None None 60679694 Common - putative methylase BF0098 133 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 60682311 Common - hypothetical protein BF2841 5 COG2319 COG2319, FOG: WD40 repeat General function prediction only 60679829 Common hppA membrane-bound proton-translocating pyrophosphatase BF0235 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 60681627 Common - putative transmembrane protein BF2148 49 COG2311 COG2311, Predicted membrane protein Function unknown 60681226 Common - hypothetical protein BF1734 3 None None None 60680312 Common - putative aldo/keto-reductase BF0757 193 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 60682472 Pathogen - hypothetical protein BF3002 1 None None None 60681879 Common - hypothetical protein BF2399 15 None None None 60681200 Common - putative capsular biosynthesis protein BF1706 185 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60681933 Common - putative conserved membrane protein BF2453 18 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60681500 Common - hypothetical protein BF2012 19 COG4104 COG4104, Uncharacterized conserved protein Function unknown 60681087 Common - putative two-component response regulator BF1590 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 60683121 Common - putative ribulose-phosphate 3-epimerase BF3672 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 60682595 Common - hypothetical protein BF3126 5 None None None 60682074 Common - putative LPS biosynthesis related glycosyltransferase BF2595 202 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60680928 Common - putative alpha-galactosidase BF1418 16 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 60681268 Pathogen traO conserved hypothetical protein found in conjugate transposon BF1776 3 None None None 60680223 Common - hypothetical protein BF0664 23 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 60679995 Common - possible acetyltransferase BF0415 7 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 60680599 Common - putative dehydrogenase/oxidoreductase BF1060 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 60681264 Pathogen traL conserved hypothetical protein found in conjugate transposon BF1772 1 None None None 60679755 Common - hypothetical protein BF0159 5 None None None 60683523 Common - putative NUDIX/MutT-family protein BF4099 109 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 60683701 Common - putative two-component system sensor kinase/response regulator fusion protein BF4286 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60682988 Common - hypothetical protein BF3530 125 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 60681930 Common - putative two component system response regulator BF2450 211 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 60682750 Common - hypothetical protein BF3282 25 COG5545 COG5545, Predicted P-loop ATPase and inactivated derivatives General function prediction only 60679611 Common - putative SAM superfamily protein BF0014 47 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 60682255 Common - putative EPS related membrane protein BF2784 145 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 60683392 Pathogen - hypothetical protein BF3957 1 None None None 60680260 Common - putative phosphatidate cytidylyltransferase BF0701 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 60681693 Common - putative ABC transport system, membrane protein BF2214 14 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 60681712 Common - putative ATP synthase delta chain BF2233 64 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 60680866 Common - putative penicillin-binding protein BF1350 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 60683549 Common - hypothetical protein BF4128 7 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60679653 Pathogen - hypothetical protein BF0057 1 None None None 60681207 Common - hypothetical protein BF1713 23 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 60680454 Common nagB glucosamine-6-phosphate deaminase BF0905 84 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 60681597 Common - hypothetical protein BF2116 3 None None None 60681302 Common bmnA beta-mannosidase BF1810 62 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60681870 Common - hypothetical protein BF2390 12 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60680613 Common - putative modification protein of type I restriction-modification system BF1077 160 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 60683143 Common - hypothetical protein BF3697 8 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 60679815 Common - cysteine desulfurase activator complex subunit SufB BF0221 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 60681177 Common - hypothetical protein BF1683 7 None None None 60681398 Common wcgR putative LPS biosynthesis related glycosyltransferase BF1908 104 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60679730 Common - putative RNA helicase dead-box protein BF0134 238 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 60682720 Common - putative cysteine synthase BF3251 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 60683550 Common pnpA polynucleotide phosphorylase/polyadenylase BF4129 238 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 60680476 Common - putative sugar transporter BF0927 47 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 60683035 Common - putative regulatory protein (possible anti-sigma factor) BF3582 28 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60682436 Common - hypothetical protein BF2966 9 None None None 60683126 Common - hypothetical protein BF3677 8 None None None 60679825 Common - putative regulatory protein BF0231 31 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60682880 Common - putative methyltransferase BF3418 144 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 60680992 Pathogen - putative transmembrane protein BF1490 1 None None None 60683421 Common rpsE 30S ribosomal protein S5 BF3986 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 60681430 Common - hypothetical protein BF1941 10 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 60682108 Common - hypothetical protein BF2629 17 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 60680569 Common wcfL putative phosphate transferase BF1026 123 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 60680294 Pathogen - possible glycosyltransferase protein BF0738 1 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60683517 Pathogen - hypothetical protein BF4093 1 None None None 60679961 Common - hypothetical protein BF0373 41 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 60679978 Common gadB putative glutamate decarboxylase BF0393 66 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 60680049 Common - putative Acyl-CoA synthetase BF0476 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 60680646 Common - hypothetical protein BF1117 102 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 60683463 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase BF4029 127 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 60680459 Common - putative haloacid dehalogenase-like hydrolase BF0910 111 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 60680801 Common - putative transmembrane cation transport P type ATPase BF1283 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 60680813 Pathogen - hypothetical protein BF1295 3 None None None 60680840 Common pflA putative pyruvate formate-lyase 1 activating enzyme BF1322 107 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 60683543 Pathogen - hypothetical protein BF4119 1 None None None 60681526 Pathogen - putative transmembrane protein BF2040 1 None None None 60683214 Common - hypothetical protein BF3769 230 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 60681067 Common rne putative ribonuclease E BF1566 186 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 60681880 Common - hypothetical protein BF2400 3 None None None 60682921 Common - putative LPS biosynthesis related glycosyltransferase BF3460 6 None None None 60680894 Common - putative methyltransferase protein BF1380 13 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 60683288 Pathogen - hypothetical protein BF3845 1 None None None 60682192 Common - putative kinase BF2719 110 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 60683395 Common - putative transmembrane protein BF3960 13 None None None 60680688 Common pth peptidyl-tRNA hydrolase BF1163 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 60682793 Pathogen - putative lipoprotein BF3325 1 None None None 60680202 Common dnaE putative DNA polymerase III alpha subunit BF0641 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 60680391 Common hemH phosphoribosylaminoimidazole-succinocarboxamide synthase BF0840 164 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 60680883 Common wzx3 putative LPS biosynthesis related flippase BF1369 161 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 60680149 Common tdk putative thymidine kinase BF0583 72 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 60682211 Common - putative ABC transport system, ATP-binding protein BF2738 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 60682651 Common - putative transport-related, membrane protein BF3182 27 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 60683054 Common pgi glucose-6-phosphate isomerase BF3604 198 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 60681537 Common - putative glycosyltransferase protein BF2052 184 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60680359 Common - putative outer membrane protein BF0807 35 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60680880 Pathogen - hypothetical protein BF1364 1 None None None 60680192 Common - hypothetical protein BF0630 3 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 60681574 Common - putative transmembrane oligopeptide transporter BF2092 42 COG1297 COG1297, Predicted membrane protein Function unknown 60681813 Common - para-aminobenzoate synthase component I BF2335 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 60682711 Common - putative exported alpha-L-fucosidase protein BF3242 33 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 60680529 Common secA preprotein translocase subunit SecA BF0983 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 60680553 Pathogen upcZ putative transcriptional regulator BF1010 1 None None None 60682769 Common - putative two-component system sensor kinase/response regulator fusion protein BF3301 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60682148 Common trpE anthranilate synthase component I BF2673 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 60683101 Pathogen - hypothetical protein BF3651 1 None None None 60679954 Common - putative beta-lactamase/acylhydrolase BF0366 151 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 60680625 Common - hypothetical protein BF1093 2 None None None 60681694 Common - putative ABC transport system, membrane protein BF2215 13 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60682197 Common - hypothetical protein BF2724 15 COG4639 COG4639, Predicted kinase General function prediction only 60683114 Common - hypothetical protein BF3665 222 COG1160 COG1160, Predicted GTPases General function prediction only 60682523 Common - putative two-component system sensor histidine kinase BF3054 186 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 60682562 Common - putative ABC transport system, ATP-binding protein BF3093 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 60681622 Pathogen - hypothetical protein BF2143 1 COG2311 COG2311, Predicted membrane protein Function unknown 60683000 Common icd putative isocitrate dehydrogenase [NADP] BF3542 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 60681159 Pathogen - hypothetical protein BF1665 1 None None None 60680605 Common - possible type I restriction-modification system protein BF1068 70 COG1479 COG1479, Uncharacterized conserved protein Function unknown 60680668 Common - putative purine nucleoside phosphorylase/uridine phosphorylase family protein BF1142 85 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 60683722 Common - putative AsnC-family transcriptional regulatory protein BF4310 157 COG1522 Lrp, Transcriptional regulators Transcription 60679869 Common - putative two-component system sensor histidine kinase/response regulator fusion protein BF0276 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60680268 Common - hypothetical protein BF0709 3 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 60681415 Common - hypothetical protein BF1926 3 None None None 60681800 Pathogen - hypothetical protein BF2322 1 None None None 60683358 Pathogen - hypothetical protein BF3921 1 None None None 60682169 Common - hypothetical protein BF2696 31 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 60680520 Common - hypothetical protein BF0974 13 None None None 60682053 Common - hypothetical protein BF2573 32 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 60680638 Common - putative beta-lactamase protein BF1108 24 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 60681294 Common - possible outer membrane protein BF1802 6 None None None 60681443 Common - putative RNA polymerase ECF-type sigma factor BF1954 167 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60682879 Pathogen - hypothetical protein BF3417 1 None None None 60683008 Common ilvB putative acetolactate synthase large subunit BF3550 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 60683631 Pathogen - hypothetical protein BF4211 2 None None None 60681916 Common - hypothetical protein BF2437 34 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60683106 Common - hypothetical protein BF3657 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 60680081 Common - putative ROK family transcriptional repressor BF0512 173 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 60680932 Common - putative ATP-binding ABC transporter protein BF1423 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 60682963 Common rffH2 putative glucose-1-phosphate thymidylyltransferase BF3505 232 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 60682173 Common - hypothetical protein BF2700 224 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60682746 Pathogen - hypothetical protein BF3278 1 None None None 60683693 Common aroQ 3-dehydroquinate dehydratase BF4278 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 60679778 Common - hypothetical protein BF0183 11 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 60679620 Common pdhD putative dihydrolipoamide dehydrogenase BF0023 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 60683014 Common - hypothetical protein BF3556 43 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60681859 Common - hypothetical protein BF2379 128 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60682517 Common - 3-oxoacyl-(acyl carrier protein) synthase III BF3047 229 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 60681287 Common - putative bacteriophage integrase BF1795 79 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60682155 Common - hypothetical protein BF2681 8 None None None 60683060 Common - hypothetical protein BF3610 20 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 60682505 Common udk uridine kinase BF3035 94 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 60682510 Common smpB SsrA-binding protein BF3040 188 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 60682127 Common - putative ABC transport system, membrane protein BF2649 152 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 60681374 Common - hypothetical protein BF1884 18 COG3855 Fbp, Uncharacterized protein conserved in bacteria Carbohydrate transport and metabolism 60679847 Common murG N-acetylglucosaminyl transferase BF0254 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 60679629 Pathogen - hypothetical protein BF0032 1 None None None 60679678 Common - 5-keto-4-deoxyuronate isomerase BF0082 27 COG3717 KduI, 5-keto 4-deoxyuronate isomerase Carbohydrate transport and metabolism 60683687 Common - putative ECF-type RNA polymerase BF4271 132 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60680315 Common - putative outer membrane protein BF0760 6 None None None 60679665 Common - putative tRNA pseudouridine synthase BF0069 244 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 60679809 Common fucK putative fuculokinase BF0214 102 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 60682917 Common - putative LPS biosynthesis related polysaccharide polymerase BF3456 6 None None None 60683608 Common suhB putative inositol-1-monophosphatase BF4187 205 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 60683454 Common rplK 50S ribosomal protein L11 BF4019 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 60682616 Common - putative LacI-family transcriptional regulator BF3147 127 COG1609 PurR, Transcriptional regulators Transcription 60681895 Pathogen - hypothetical protein BF2416 2 None None None 60680615 Common - putative type I restriction enzyme BF1079 136 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 60682286 Pathogen - hypothetical protein BF2815 1 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60681765 Pathogen - hypothetical protein BF2287 1 None None None 60681547 Common - hypothetical protein BF2063 15 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 60681750 Pathogen - hypothetical protein BF2271 3 None None None 60682316 Pathogen - hypothetical protein BF2846 1 None None None 60682252 Common - putative recombinase/integrase BF2780 32 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60681150 Common - 2-ketoisovalerate ferredoxin reductase BF1656 132 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 60683457 Common tuf elongation factor Tu BF4022 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 60679714 Common - hypothetical protein BF0118 94 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 60681726 Common - putative iron transport related membrane protein BF2247 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 60683295 Common - putative outer membrane protein BF3853 9 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60683342 Common - hypothetical protein BF3905 7 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 60682888 Common - hypothetical protein BF3426 6 None None None 60680337 Common nuoN putative NADH dehydrogenase chain N BF0783 207 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 60680926 Common - putative outer membrane protein BF1416 5 None None None 60682093 Common rnfA electron transport complex protein RnfA BF2614 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 60680096 Common - putative two-component response regulator-like protein BF0527 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 60682908 Common - putative peptidase BF3447 195 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 60680707 Common - hypothetical protein BF1182 57 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 60683045 Common - hypothetical protein BF3594 59 COG2985 COG2985, Predicted permease General function prediction only 60682718 Common recQ2 putative ATP-dependent DNA helicase BF3249 234 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 60680019 Common - hypothetical protein BF0441 4 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 60681864 Common - hypothetical protein BF2384 6 None None None 60683481 Common - hypothetical protein BF4053 23 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 60679936 Pathogen - hypothetical protein BF0347 1 None None None 60679689 Common - hypothetical protein BF0093 89 COG4121 COG4121, Uncharacterized conserved protein Function unknown 60682557 Common - putative exported hexosaminidase BF3088 60 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60683738 Common - putative two-component system sensor kinase/response regulator fusion protein BF4326 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60680068 Common - putative melibiase BF0498 46 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 60681980 Common batB aerotolerance-related membrane protein BF2500 70 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 60682468 Pathogen - hypothetical protein BF2998 1 None None None 60681477 Common - putative AraC-family transcriptional regulator BF1989 37 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60680335 Common - putative TonB-dependent receptor protein BF0781 31 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60681673 Common - hypothetical protein BF2194 19 None None None 60681045 Pathogen - hypothetical protein BF1544 1 None None None 60680478 Common rpmA 50S ribosomal protein L27 BF0929 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 60680176 Common - putative transmembrane amino-terminal protease BF0611 12 None None None 60680892 Common pdiA hypothetical protein BF1378 110 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60681629 Common - putative IS element BF2150 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 60679745 Pathogen - hypothetical protein BF0149 1 None None None 60679599 Common - putative outer membrane protein BF0002 6 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60679647 Pathogen - hypothetical protein BF0050 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60681523 Pathogen - putative transmembrane protein BF2037 1 None None None 60682073 Common - putative LPS biosynthesis related glycosyltransferase BF2594 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60679708 Common apt adenine phosphoribosyltransferase BF0112 169 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 60681945 Common - putative hydrolase BF2465 205 COG0388 COG0388, Predicted amidohydrolase General function prediction only 60679671 Common - possible uroporphyrinogen-III synthase BF0075 6 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 60679840 Common rpsT 30S ribosomal protein S20 BF0247 20 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 60679631 Pathogen - hypothetical protein BF0034 1 None None None 60680436 Common gap putative glyceraldehyde 3-phosphate dehydrogenase BF0885 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 60680376 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase BF0825 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 60680900 Common - hypothetical protein BF1386 138 COG1741 COG1741, Pirin-related protein General function prediction only 60681235 Common - hypothetical protein BF1743 4 None None None 60679813 Common infB translation initiation factor IF-2 BF0219 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 60680300 Common - putative UDP-GlcNAc 2-epimerase BF0744 154 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 60682247 Common - hypothetical protein BF2775 157 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 60681349 Pathogen - hypothetical protein BF1858 2 None None None 60682532 Common - putative ABC transport system, ATP-binding protein BF3063 245 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 60681953 Common - hypothetical protein BF2473 100 COG0327 COG0327, Uncharacterized conserved protein Function unknown 60681996 Common - hypothetical protein BF2516 22 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 60680812 Common - putative transmembrane protein BF1294 48 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 60681198 Common - putative endonuclease BF1704 53 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 60682907 Pathogen - putative lipoprotein BF3446 1 None None None 60681799 Pathogen - hypothetical protein BF2321 1 None None None 60679796 Common - putative lipoprotein BF0201 27 None None None 60679785 Common rnh1 putative ribonuclease H1 BF0190 17 COG3341 COG3341, Predicted double-stranded RNA/RNA-DNA hybrid binding protein General function prediction only 60680715 Common - putative transporter periplasmic binding protein BF1190 60 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 60683357 Common - hypothetical protein BF3920 4 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 60682439 Pathogen - hypothetical protein BF2969 1 None None None 60683617 Pathogen - hypothetical protein BF4196 2 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 60679764 Common - putative two-component regulator sensor kinase BF0169 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60680407 Common - putative beta-glucuronidase BF0856 54 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60680655 Common - hypothetical protein BF1126 61 COG3943 COG3943, Virulence protein General function prediction only 60681435 Common - putative beta-galactosidase BF1946 74 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60683273 Pathogen - hypothetical protein BF3830 1 None None None 60682367 Common - hypothetical protein BF2897 30 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 60683080 Common rplI 50S ribosomal protein L9 BF3630 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 60682143 Common - hypothetical protein BF2667 20 COG3247 HdeD, Uncharacterized conserved protein Function unknown 60683051 Common - putative cation transport related membrane protein BF3601 175 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60680753 Pathogen - conserved hypothetical protein found in conjugate transposon BF1233 3 None None None 60679619 Pathogen - hypothetical protein BF0022 1 None None None 60681323 Pathogen - hypothetical protein BF1831 1 None None None 60683534 Common - putative transcriptional regulator GerE, LuxR family BF4110 59 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 60680199 Pathogen - hypothetical protein BF0638 1 None None None 60681223 Common - hypothetical protein BF1731 3 None None None 60681587 Common recR putative RecR-family recombination protein BF2106 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 60681978 Common batD aerotolerance-related exported protein BF2498 26 None None None 60679940 Pathogen - hypothetical protein BF0352 3 None None None 60681382 Pathogen - hypothetical protein BF1892 1 None None None 60682001 Common - putative alpha-ribazole-5'-phosphate phosphatase BF2521 69 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 60682811 Pathogen - hypothetical protein BF3346 1 None None None 60682624 Common - putative two-component system sensor kinase/response regulator fusion protein BF3155 224 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 60682461 Pathogen - hypothetical protein BF2991 1 None None None 60682678 Common - putative sulfatase BF3209 64 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 60681658 Pathogen - hypothetical protein BF2179 2 None None None 60682428 Pathogen - hypothetical protein BF2958 1 None None None 60680193 Common - hypothetical protein BF0631 3 None None None 60680214 Common - putative ABC transporter membrane protein BF0655 194 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 60679837 Common - hypothetical protein BF0244 9 None None None 60680804 Pathogen - hypothetical protein BF1286 1 None None None 60681903 Pathogen - hypothetical protein BF2424 2 None None None 60680014 Common - hypothetical protein BF0436 17 None None None 60681175 Common - putative outer membrane protein BF1681 49 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 60683181 Common - putative thiamine biosynthesis related protein BF3736 124 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 60680986 Common - hypothetical protein BF1484 3 None None None 60682258 Pathogen - hypothetical protein BF2787 1 None None None 60681112 Common bioF 8-amino-7-oxononanoate synthase BF1616 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 60681792 Pathogen - hypothetical protein BF2314 1 None None None 60681599 Common - hypothetical protein BF2118 4 None None None 60682187 Common nrdF ribonucleotide-diphosphate reductase subunit beta BF2714 156 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 60681075 Pathogen - hypothetical protein BF1574 2 None None None 60683502 Pathogen - hypothetical protein BF4078 1 None None None 60680185 Pathogen - hypothetical protein BF0622 1 None None None 60681320 Pathogen - hypothetical protein BF1828 3 None None None 60680461 Common - putative O-acetylhomoserine synthase BF0912 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 60679917 Common - putative beta-galactosidase BF0328 75 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60680133 Common - putative TonB-dependent transmembrane receptor protein BF0565 49 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680243 Common - putative anti-sigma factor BF0684 38 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60682163 Common fldA flavodoxin FldA BF2689 72 COG0716 FldA, Flavodoxins Energy production and conversion 60683178 Common - putative nucleoside diphosphate kinase BF3733 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 60682376 Common - hypothetical protein BF2906 6 None None None 60682326 Common - putative DNA polymerase III epsilon chain BF2856 98 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 60682844 Pathogen - hypothetical protein BF3382 2 None None None 60679854 Common mraW S-adenosyl-methyltransferase MraW BF0261 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 60682449 Common - putative ABC transport system, membrane protein BF2979 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 60682381 Pathogen - hypothetical protein BF2911 1 None None None 60682539 Common - hypothetical protein BF3070 38 None None None 60683228 Common - putative translation initation factor BF3783 37 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 60683449 Common rpoC DNA-directed RNA polymerase subunit beta' BF4014 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 60683285 Pathogen - hypothetical protein BF3842 1 None None None 60679802 Pathogen - hypothetical protein BF0207 1 None None None 60680732 Common ahpF alkyl hydroperoxide reductase subunit F BF1209 247 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 60679931 Pathogen - hypothetical protein BF0342 1 None None None 60681568 Common - putative TonB-dependent outer membrane receptor protein BF2084 24 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60681540 Common - putative transmembrane O-antigen flippase BF2055 116 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 60680163 Common - hypothetical protein BF0597 6 None None None 60680486 Common - hypothetical protein BF0937 55 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 60681850 Pathogen - putative lipoprotein BF2370 2 None None None 60680071 Common - putative outer membrane protein BF0501 10 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60679725 Common - possible polysaccharide biosynthesis transmembrane protein BF0129 57 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 60680767 Pathogen - hypothetical protein BF1247 1 None None None 60680154 Common - putative amino acid transporter BF0588 159 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 60682357 Common ftsE Cell division ATP-binding protein BF2887 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 60681789 Common - putative type I restriction modification system related protein BF2311 20 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 60683069 Common - putative ribonucleoside reductase BF3619 214 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 60683669 Common - hypothetical protein BF4251 3 None None None 60679830 Common - hypothetical protein BF0237 11 None None None 60681232 Common - hypothetical protein BF1740 7 None None None 60679756 Common - putative phenylacetic acid degradation protein BF0160 49 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 60680395 Pathogen - putative transmembrane protein BF0844 1 None None None 60683765 Common - putative transmembrane protein BF4354 5 None None None 60683572 Common - putative two-component system sensor kinase/response regulator fusion protein BF4150 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60681507 Pathogen - hypothetical protein BF2019 1 None None None 60681849 Common - putative signal peptidase BF2369 66 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60682574 Common - putative transport related, membrane protein BF3105 204 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60682832 Common - hypothetical protein BF3369 3 None None None 60680364 Common - hypothetical protein BF0812 89 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 60681122 Common - hypothetical protein BF1626 70 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 60682856 Pathogen - hypothetical protein BF3394 2 None None None 60680574 Common adk adenylate kinase BF1032 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 60683154 Common - putative sialidase BF3709 18 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 60680909 Common - 7-cyano-7-deazaguanine reductase BF1397 145 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 60681530 Common - hypothetical protein BF2045 4 None None None 60682100 Pathogen - hypothetical protein BF2621 1 None None None 60681832 Common fabD malonyl CoA-acyl carrier protein transacylase BF2352 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 60681453 Common - putative RNA polymerase ECF-type sigma factor BF1964 123 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60682260 Pathogen - hypothetical protein BF2789 3 None None None 60679966 Common - conserved hypothetical lipoprotein BF0380 5 None None None 60682898 Common gdhB glutamate dehydrogenase BF3437 169 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 60682773 Common - putative lipoprotein BF3305 20 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 60682412 Common - hypothetical protein BF2942 11 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60679874 Common - hypothetical protein BF0281 29 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 60682459 Common - putative signal peptidase I BF2989 154 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 60680929 Pathogen - hypothetical protein BF1419 1 None None None 60679957 Common - putative transmembrane protein BF0369 18 COG4299 COG4299, Uncharacterized protein conserved in bacteria Function unknown 60679776 Common pdxB erythronate-4-phosphate dehydrogenase BF0181 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 60682221 Pathogen - hypothetical protein BF2748 4 None None None 60680462 Common - putative RNA polymerase ECF-type sigma factor BF0913 7 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60679992 Common - hypothetical protein BF0412 3 None None None 60683070 Common - putative alpha-glucanotransferase BF3620 121 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 60681119 Common - putative propionyl-CoA carboxylase BF1623 213 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 60682433 Common - putative transcription-repair coupling factor BF2963 212 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 60679646 Pathogen - hypothetical protein BF0049 1 None None None 60680350 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase BF0796 222 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 60682072 Common - putative LPS biosynthesis related glycosyltransferase BF2593 189 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60682547 Pathogen - hypothetical protein BF3078 1 None None None 60681414 Common - putative urea transport protein BF1925 19 COG4413 Utp, Urea transporter Amino acid transport and metabolism 60683598 Common - putative outer membrane protein BF4177 6 None None None 60683179 Common - putative ATP-dependent DNA helicase BF3734 223 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 60680826 Common - putative RNA polymerase ECF-type sigma factor BF1308 49 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60682000 Common - putative cobalamin 5'-phosphate synthase BF2520 52 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 60682918 Common - putative LPS biosynthesis related glycosyltransferase BF3457 109 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60682934 Common - putative ribose 5-phosphate isomerase BF3474 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 60683664 Common - putative outer membrane protein BF4246 38 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60680238 Common - putative ATP-dependent exodeoxyribonuclease BF0679 96 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 60680770 Common - putative transmembrane mobilisation protein BF1250 14 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 60683546 Common - putative mannose-1-phosphate guanylyltransferase BF4125 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 60680114 Common aspC1 putative aspartate aminotransferase BF0545 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 60681840 Common - putative thioredoxin peroxidase BF2360 222 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60681166 Common - putative beta-galactosidase BF1672 71 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60682733 Common leuB putative 3-isopropylmalate dehydrogenase BF3263 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 60682851 Common - putative RNA polymerase sigma fator BF3389 88 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60682863 Common - hypothetical protein BF3401 53 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 60682876 Pathogen - hypothetical protein BF3414 1 COG3325 ChiA, Chitinase Carbohydrate transport and metabolism 60680752 Pathogen - conserved hypothetical protein found in conjugate transposon BF1232 3 None None None 60681586 Pathogen - hypothetical protein BF2105 1 None None None 60682508 Common - putative nitroreductase BF3038 44 COG0778 NfnB, Nitroreductase Energy production and conversion 60680583 Pathogen - hypothetical protein BF1044 1 None None None 60683163 Common - putative prephenate dehydrogenase family protein BF3718 17 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 60682066 Common - putative lipoprotein BF2587 3 None None None 60682948 Common - putative hydrolase BF3488 40 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 60681897 Pathogen - hypothetical protein BF2418 1 None None None 60681028 Common - putative cation efflux protein BF1527 9 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60682427 Pathogen - hypothetical protein BF2957 1 None None None 60680363 Common - hypothetical protein BF0811 3 None None None 60680686 Pathogen - hypothetical protein BF1161 1 None None None 60682766 Common - putative acetyltransferase BF3298 205 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 60681240 Common - hypothetical protein BF1748 4 None None None 60683378 Common - putative ATP-binding component of ABC transporter BF3941 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 60682176 Common - putative metal transport-related membrane protein BF2703 169 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 60682575 Common - putative endonuclease BF3106 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 60681238 Common - hypothetical protein BF1746 4 None None None 60682936 Common - putative acetyltransferase BF3476 108 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 60683324 Common - hypothetical protein BF3887 9 None None None 60682835 Common - hypothetical protein BF3372 102 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 60683674 Common - putative outer membrane protein BF4256 11 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60682190 Common - hypothetical protein BF2717 22 COG3610 COG3610, Uncharacterized conserved protein Function unknown 60682413 Common - hypothetical protein BF2943 10 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60681461 Common - hypothetical protein BF1973 4 None None None 60681975 Common - hypothetical protein BF2495 56 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 60683155 Pathogen - hypothetical protein BF3710 2 None None None 60679895 Pathogen - hypothetical protein BF0305 1 None None None 161723188 Common hcp hydroxylamine reductase BF2204 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 60682418 Common - hypothetical protein BF2948 125 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 60683075 Common - putative glycosyl transferase BF3625 135 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 60681396 Common wcgQ putative LPS biosynthesis related glycosyltransferase BF1906 186 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60679818 Common - putative ABC transporter protein BF0224 174 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 60681520 Common - putative TetR-family transcriptional regulator BF2032 13 COG1309 AcrR, Transcriptional regulator Transcription 60680111 Common - hypothetical protein BF0542 6 None None None 60681565 Common gidB glucose-inhibited division protein B BF2081 199 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 60683001 Common acn aconitate hydratase BF3543 223 COG1048 AcnA, Aconitase A Energy production and conversion 60682109 Common - putative PadR-family transcriptional regulatory protein BF2630 59 COG1695 COG1695, Predicted transcriptional regulators Transcription 60682955 Common - hypothetical protein BF3496 6 None None None 60681923 Common - hypothetical protein BF2442 3 None None None 60681745 Pathogen - hypothetical protein BF2266 2 None None None 60682839 Common - hypothetical protein BF3376 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 60683404 Common ftcD putative formimidoyltransferase-cyclodeaminase BF3969 22 COG3643 COG3643, Glutamate formiminotransferase Amino acid transport and metabolism 60679989 Pathogen - hypothetical protein BF0406 1 None None None 60682448 Common - putative ABC transport system, ATP-binding protein BF2978 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 60679668 Common metK S-adenosylmethionine synthetase BF0072 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 60681822 Common - conserved putative DNA-binding hypothetical protein BF2344 18 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 60682654 Common - conserved hypothetical phospholipase BF3185 51 COG4667 COG4667, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 60682738 Pathogen - putative lipoprotein BF3268 1 None None None 60680469 Common - putative glycosyl transferase BF0920 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60683544 Common - putative acetyltransferase BF4120 105 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 60680213 Common - putative ATP/GTP-binding transmembrane protein BF0654 206 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 60682342 Pathogen - hypothetical protein BF2872 2 None None None 60682806 Common - putative carboxyl transferase BF3339 215 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 60679660 Pathogen - hypothetical protein BF0064 1 None None None 60683626 Pathogen - hypothetical protein BF4206 1 None None None 60681770 Pathogen - hypothetical protein BF2292 1 None None None 60680428 Common - putative DNA replication and repair protein BF0877 159 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 60682634 Pathogen - hypothetical protein BF3165 3 None None None 60681772 Common - hypothetical protein BF2294 43 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60682972 Common - hypothetical protein BF3514 4 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 60680654 Pathogen - hypothetical protein BF1125 1 None None None 60680946 Common - putative AraC family transcriptional regulator BF1437 91 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60683566 Common - putative transmembrane CAAX amino terminal protease family BF4145 60 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 60680977 Pathogen - hypothetical protein BF1475 1 None None None 60682282 Pathogen - hypothetical protein BF2811 1 None None None 60683745 Common parE DNA topoisomerase IV subunit B BF4333 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 60680537 Common - putative transmembrane CBS domain transporter BF0993 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 60680754 Common - conserved hypothetical protein found in conjugate transposon BF1234 5 None None None 60681096 Common - hypothetical protein BF1600 12 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 60681127 Common lpd putative dihydrolipoamide dehydrogenase BF1631 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 60681364 Common - putative 2', 3'-cyclic nucleotide 2'-phosphodiesterase BF1873 134 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 60682020 Common - putative cobalt chelatase BF2540 24 COG4822 CbiK, Cobalamin biosynthesis protein CbiK, Co2+ chelatase Coenzyme metabolism 60683305 Common - putative copper transport-related membrane protein BF3863 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 60680858 Common metY putative O-acetylhomoserine sulfhydrylase BF1342 207 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 60682235 Common - putative muconate cycloisomerase BF2763 125 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 60681655 Common - putative AsnC-family transcriptional regulator BF2176 160 COG1522 Lrp, Transcriptional regulators Transcription 60682636 Common - hypothetical protein BF3167 5 COG3296 COG3296, Uncharacterized protein conserved in bacteria Function unknown 60681558 Common - hypothetical protein BF2074 47 COG4198 COG4198, Uncharacterized conserved protein Function unknown 60680716 Common nfo endonuclease IV BF1191 97 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 60683025 Common - putative exported phosphoesterase protein BF3570 77 COG1520 COG1520, FOG: WD40-like repeat Function unknown 60680251 Common - putative RelA/SpoT GTP pyrophosphokinase BF0692 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 60681514 Common - hypothetical protein BF2026 2 None None None 60680073 Common - putative ECF-type RNA polymerase sigma factor BF0503 57 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60680671 Common - hypothetical protein BF1145 7 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 60681715 Common - putative helicase BF2236 62 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 60683120 Common - putative competence related membrane protein BF3671 200 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 60680809 Pathogen - putative transmembrane protein BF1291 1 None None None 60680053 Common argC N-acetyl-gamma-glutamyl-phosphate reductase BF0480 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 60680517 Common - putative outer membrane protein BF0971 10 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60681135 Pathogen - hypothetical protein BF1641 1 None None None 60680787 Common - putative haloacid dehalogenase-like hydrolase BF1268 77 COG0546 Gph, Predicted phosphatases General function prediction only 60683468 Common - putative primosomal protein N' BF4034 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 60680158 Common - putative surface membrane protein BF0592 10 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60680414 Common - putative outer membrane protein BF0863 6 None None None 60680791 Pathogen - hypothetical protein BF1272 1 None None None 60683648 Pathogen - hypothetical protein BF4228 1 None None None 60681146 Common - hypothetical protein BF1652 6 None None None 60681501 Common - hypothetical protein BF2013 60 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 60682025 Common - putative transport-related membrane protein BF2545 20 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 60680930 Common - putative histidine decarboxylase BF1421 6 None None None 60681779 Pathogen - putative lipoprotein BF2301 1 None None None 60682292 Pathogen - hypothetical protein BF2821 2 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 60681116 Common lctP putative L-lactate permease BF1620 104 COG1620 LldP, L-lactate permease Energy production and conversion 60682692 Common groES co-chaperonin GroES BF3223 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 60680706 Common bcp putative bacterioferritin comigratory protein BF1181 224 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60681310 Common dnaJ putative chaperone protein BF1818 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 60682600 Common mmdB putative methylmalonyl-CoA decarboxylase, beta subunit BF3131 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 60679612 Common - hypothetical protein BF0015 15 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 60680674 Common apbE putative thiamine biosynthesis lipoprotein BF1148 138 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 60681181 Pathogen - hypothetical protein BF1687 1 None None None 60682310 Common - putative two-component system, histidine kinase BF2840 202 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 60682830 Common - hypothetical protein BF3366 16 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60683237 Common purB adenylosuccinate lyase BF3792 238 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 60682377 Common - hypothetical protein BF2907 12 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60682319 Common - conserved hypothetical PhoH-like protein BF2849 192 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 60683348 Common gldH putative gliding motility protein BF3911 6 None None None 60681596 Pathogen - hypothetical protein BF2115 1 None None None 60683700 Pathogen - hypothetical protein BF4285 1 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 60679883 Pathogen - hypothetical protein BF0290 2 None None None 60681619 Common - hypothetical protein BF2140 2 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 60680598 Common - putative glycosyl hydrolase BF1059 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 60680044 Pathogen - hypothetical protein BF0471 1 None None None 60683499 Common - possible recombination enzyme BF4075 10 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60681964 Common trmD tRNA (guanine-N(1)-)-methyltransferase BF2484 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 60682059 Pathogen - putative transport-related membrane protein BF2580 3 None None None 60681178 Pathogen - hypothetical protein BF1684 2 None None None 60683144 Pathogen updZ putative transcriptional regulator BF3698 1 None None None 60681005 Pathogen - hypothetical protein BF1503 1 None None None 60679826 Common - putative ECF-type sigma factor BF0232 155 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60681046 Common - hypothetical protein BF1545 6 None None None 60680224 Common - putative beta-galactosidase BF0665 71 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60683280 Pathogen - hypothetical protein BF3837 2 None None None 60682083 Common - putative LPS biosynthesis related DNTP-hexose dehydratase-epimerase BF2604 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 60682299 Pathogen - hypothetical protein BF2828 1 None None None 60683516 Common - hypothetical protein BF4092 10 COG5279 CYK3, Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain Cell division and chromosome partitioning 60681267 Common traN conserved hypothetical protein found in conjugate transposon BF1775 5 None None None 60682881 Common - hypothetical protein BF3419 3 None None None 60679713 Pathogen - hypothetical protein BF0117 1 None None None 60680696 Pathogen - hypothetical protein BF1171 1 None None None 60682251 Common mpi multiple promoter invertase BF2779 118 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 60682285 Common - hypothetical protein BF2814 5 None None None 60683522 Pathogen - hypothetical protein BF4098 1 None None None 60683037 Common aroC chorismate synthase BF3584 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 60680451 Common - putative transmembrane and transcriptional regulatory protein BF0902 34 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 60680614 Common - putative modification protein of type I restriction-modification system BF1078 73 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 60683551 Common - putative RNA polymerase ECF-type sigma factor BF4130 50 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60679720 Pathogen - hypothetical protein BF0124 1 None None None 60680349 Common trkA potassium transporter peripheral membrane component BF0795 155 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 60680729 Common - putative phosphohydrolase, Icc family BF1206 8 COG1409 Icc, Predicted phosphohydrolases General function prediction only 60681920 Pathogen - hypothetical protein BF2439B 1 None None None 60680833 Common - putative transmembrane protein BF1315 100 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60681878 Pathogen - hypothetical protein BF2398 1 None None None 60683716 Common - putative UDP-N-acetyl-D-mannosamine dehydrogenase BF4304 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 60681639 Common - hypothetical protein BF2160 6 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60683100 Pathogen - hypothetical protein BF3650 1 None None None 60683388 Common - hypothetical protein BF3951 40 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 60683723 Common - putative transmembrane protein BF4311 7 None None None 60683394 Common - hypothetical protein BF3959 11 None None None 60683779 Common - possible chloramphenicol acetyltransferase BF4368 21 COG4845 COG4845, Chloramphenicol O-acetyltransferase Defense mechanisms 60683422 Common rplR 50S ribosomal protein L18 BF3987 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 60682526 Common - putative thiol:disulfide oxidoreductase BF3057 164 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60680802 Common - hypothetical protein BF1284 22 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 60680645 Common - putative DNA-binding protein BF1116 6 COG1396 HipB, Predicted transcriptional regulators Transcription 60682920 Common - putative LPS biosynthesis related glycosyltransferase BF3459 154 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60683464 Common gltX glutamyl-tRNA synthetase BF4030 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 60681632 Common - putative lipoprotein BF2153 149 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 161723187 Common - methylcitrate synthase BF3541 192 COG0372 GltA, Citrate synthase Energy production and conversion 60682405 Common - hypothetical protein BF2935 135 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 60680747 Common - hypothetical protein BF1224 2 None None None 60682594 Common - hypothetical protein BF3125 44 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 60682725 Common - hypothetical protein BF3255 40 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682987 Pathogen - hypothetical protein BF3529 3 None None None 60680895 Pathogen - hypothetical protein BF1381 1 None None None 60681088 Common - hypothetical protein BF1592 5 None None None 60683207 Common - putative transport-related membrane protein BF3762 48 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 60681881 Pathogen - hypothetical protein BF2402 1 None None None 60680328 Common - hypothetical protein BF0774 45 COG2942 COG2942, N-acyl-D-glucosamine 2-epimerase Carbohydrate transport and metabolism 60682077 Common - putative LPS biosynthesis related polysaccharide transporter/flippase BF2598 16 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60681285 Common - hypothetical protein BF1793 4 None None None 60683558 Common - butyrate kinase BF4137 134 COG3426 COG3426, Butyrate kinase Energy production and conversion 60681303 Common nahB beta-N-acetylhexosaminidase BF1811 61 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60680308 Pathogen - hypothetical protein BF0753 1 None None None 60680814 Common rmlD putative dTDP-dehydrorhamnose reductase BF1296 172 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 60683473 Common ansB L-asparaginase II BF4039 142 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 60680995 Pathogen - hypothetical protein BF1493 1 None None None 60683784 Common - putative transmembrane protein BF4373 47 COG1284 COG1284, Uncharacterized conserved protein Function unknown 60680721 Common - putative alpha-glucosidase, glycosylhydrolase BF1196 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 60679960 Common - putative transmembrane permease BF0372 100 None None None 60682130 Common - hypothetical protein BF2652 21 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60682592 Pathogen - hypothetical protein BF3123 1 None None None 60680381 Common - hypothetical protein BF0830 85 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 60682334 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase BF2864 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 60682666 Common - putative two component system, sensor protein BF3197 102 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 60680181 Common - ribosome-associated GTPase BF0618 163 COG1162 COG1162, Predicted GTPases General function prediction only 60680913 Common - putative RNA polymerase ECF-type sigma factor BF1401 148 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60682040 Common thiC thiamine biosynthesis protein ThiC BF2560 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 60682681 Common - putative aldolase BF3212 117 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 60679693 Common - putative exported dipeptidyl peptidase IV BF0097 95 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 60681643 Common - putative TonB-related exported protein BF2164 122 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60680281 Common - possible HipA-like protein BF0724 16 None None None 60683366 Common - putative two-component response regulator transcriptional regulatory protein BF3929 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 60680231 Common aroB putative 3-dehydroquinate synthase BF0672 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 60681803 Common - putative DNA primase BF2325 65 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 60680832 Pathogen - hypothetical protein BF1314 1 None None None 60680125 Common - putative L-asparaginase I BF0556 134 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 60681742 Common - hypothetical protein BF2263 47 COG2431 COG2431, Predicted membrane protein Function unknown 60680269 Common - hypothetical protein BF0710 3 None None None 60680433 Common - putative deoxycytidylate deaminase BF0882 113 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 60681272 Common radC3 putative DNA repair protein BF1780 169 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 60681735 Common fhs formate--tetrahydrofolate ligase BF2256 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 60683200 Common - hypothetical protein BF3754 6 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60682397 Pathogen - hypothetical protein BF2927 1 None None None 60681705 Common purT phosphoribosylglycinamide formyltransferase 2 BF2226 211 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 60680637 Pathogen - hypothetical protein BF1107 1 None None None 60682016 Common - hypothetical protein BF2536 19 COG3610 COG3610, Uncharacterized conserved protein Function unknown 60681932 Common - hypothetical protein BF2452 135 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60682825 Common - putative hydrolase BF3361 32 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 60681901 Pathogen - hypothetical protein BF2422 2 None None None 60681810 Pathogen - hypothetical protein BF2331 1 None None None 60682518 Common - cytoplasmic alpha-amylase BF3048 103 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 60681681 Common - potassium/proton antiporter BF2202 135 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 60683256 Common - putative hemolysin secretion transport system ATP-binding protein BF3812 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 60682012 Common - putative two-component system sensor histidine kinase BF2532 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60683250 Common tsr15 tyrosine site-specific recombinase BF3806 10 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60683359 Common - hypothetical protein BF3922 6 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 60679866 Common - hypothetical protein BF0273 110 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 60681031 Common rteB putative two-component system response regulator BF1530 209 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 60679771 Common pfkA 6-phosphofructokinase BF0176 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 60683013 Common - putative lipoprotein BF3555 5 None None None 60680003 Common ackA putative acetate kinase BF0424 162 COG0282 ackA, Acetate kinase Energy production and conversion 60681011 Pathogen - hypothetical protein BF1509 1 None None None 60683129 Common - DNTP-hexose dehydratase-epimerase BF3683 181 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60680022 Pathogen - hypothetical protein BF0445 1 None None None 60682753 Common bmgA mobilization protein BF3285 23 None None None 60683243 Pathogen aapG hypothetical protein BF3798 1 None None None 60682941 Common - putative oxidoreductase BF3481 17 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 60681078 Pathogen - hypothetical protein BF1579 1 None None None 60680385 Pathogen - hypothetical protein BF0834 1 None None None 60679695 Common - putative serine acetyltransferase BF0099 192 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 60683095 Pathogen - hypothetical protein BF3646 2 None None None 60680953 Common - putative two-component system sensor histidine kinase BF1447 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60680848 Pathogen - hypothetical protein BF1331 1 None None None 60683313 Pathogen - putative lipoprotein BF3876 2 None None None 60681749 Common - hypothetical protein BF2270 42 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60680818 Common - possible isochorismate synthase BF1300 210 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 60683642 Common - putative transmembrane rhomboid family protein BF4222 59 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 60679916 Common - hypothetical protein BF0327 19 COG4289 COG4289, Uncharacterized protein conserved in bacteria Function unknown 60680512 Common - putative transmembrane zinc-binding protein BF0965 7 None None None 60680398 Common truA tRNA pseudouridine synthase A BF0847 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 60682829 Common - putative metal transport-related, exported protein BF3365 151 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60683128 Common - putative phosphotransferase BF3682 146 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 60681113 Common bioA putative adenosylmethionine-8-amino-7-oxononanoate aminotransferase BF1617 238 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 60682704 Common - putative glycosyl transferase BF3235 199 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60681385 Common wcfT putative LPS biosynthesis related membrane protein BF1895 6 None None None 60680471 Pathogen - hypothetical protein BF0922 3 None None None 60682855 Common - conserved exported hypothetical protein BF3393 47 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 60681185 Common def peptide deformylase BF1691 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 60681306 Common - putative outer membrane protein BF1814 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 60682382 Pathogen - hypothetical protein BF2912 1 None None None 60681863 Pathogen - hypothetical protein BF2383 3 None None None 60682033 Pathogen - hypothetical protein BF2553 1 None None None 60682643 Common - putative two-component system sensor kinase/response regulator fusion protein BF3174 225 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 60681798 Pathogen - hypothetical protein BF2320 1 None None None 60683618 Common - possible regulatory protein BF4197 61 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 60683678 Common - putative transcriptional regulator BF4260 121 COG1396 HipB, Predicted transcriptional regulators Transcription 60679655 Common - putative lipoprotein BF0059 7 None None None 60680906 Common - putative RNA polymerase ECF-type sigma factor BF1394 160 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60683440 Common fusA elongation factor G BF4005 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 60679715 Pathogen - hypothetical protein BF0119 1 None None None 60679621 Common dacB putative exported D-alanyl-D-alanine carboxypeptidase penicillin-binding protein BF0024 101 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 60679831 Pathogen - hypothetical protein BF0238 1 None None None 60681548 Common - putative aminopeptidase BF2064 16 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 60682897 Common - hypothetical protein BF3435 22 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 60682889 Pathogen - hypothetical protein BF3427 1 None None None 60681614 Common - putative amidohydrolase BF2135 39 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 60683671 Pathogen - hypothetical protein BF4253 1 None None None 60679909 Common - putative AMP binding long chain acyl-CoA synthetase BF0320 213 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 60682116 Common - hypothetical protein BF2637 9 None None None 60682283 Pathogen - hypothetical protein BF2812 1 None None None 60679937 Common - putative TonB dependent outer membrane exported protein BF0349 10 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60679857 Pathogen - hypothetical protein BF0264 1 None None None 60681346 Pathogen - hypothetical protein BF1855 2 None None None 60683164 Pathogen - hypothetical protein BF3719 1 None None None 60680220 Common - putative outer membrane protein BF0661 18 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60681436 Common - hypothetical protein BF1947 6 None None None 60680440 Common - hypothetical protein BF0889 3 None None None 60681171 Common cysN sulfate adenylyltransferase subunit 1 BF1677 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 60682760 Common - hypothetical protein BF3292 27 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 60683577 Common - conserved hypothetical exported protein, possible ATP/GTP-binding BF4155 4 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 60681129 Common - putative dihydrolipoamide acetyltransferase BF1635 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 60682050 Pathogen - putative lipoprotein BF2570 1 None None None 60680155 Common - hypothetical protein BF0589 5 None None None 60682947 Common - putative aminotransferase BF3487 177 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 60683418 Common secY preprotein translocase subunit SecY BF3983 218 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 60680526 Common - putative arylsulfatase BF0980 80 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60681909 Pathogen - hypothetical protein BF2430 1 None None None 60683413 Common rpsK 30S ribosomal protein S11 BF3978 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 60680203 Common trxA putative thioredoxin BF0642 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 60682989 Common - putative DNAse related protein BF3531 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 60683096 Common - hypothetical protein BF3647 18 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 60679889 Common - putative exported alpha-1,2-mannosidase BF0298 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 60683195 Common - hypothetical protein BF3749 10 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 60680375 Pathogen - hypothetical protein BF0824 2 None None None 60683666 Common - putative outer membrane protein BF4248 25 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60679768 Common - putative SNF family helicase BF0173 120 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 60680758 Common - conserved hypothetical transmembrane protein found in conjugate transposon BF1238 4 None None None 60683085 Common rprX two-component regulatory system, sensor kinase protein BF3635 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60679735 Common - putative peptidase BF0139 198 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 60683274 Common - hypothetical protein BF3831 9 COG1340 COG1340, Uncharacterized archaeal coiled-coil protein Function unknown 60680506 Common rpsA 30S ribosomal protein S1 BF0959 217 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 60679604 Common - hypothetical protein BF0007 3 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 60680296 Pathogen - possible glycosyltransferase BF0740 1 None None None 60680159 Common - putative integrase/transposase BF0593 152 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60681411 Pathogen - hypothetical protein BF1922 1 None None None 60681584 Common - putative transmembrane sodium-solute transporter BF2102 55 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 60681256 Pathogen traD conserved hypothetical protein found in conjugate transposon BF1764 1 None None None 60682308 Common - putative iron-transport related outer membrane protein BF2838 108 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680910 Common - hypothetical protein BF1398 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 60680379 Common lpxC bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase BF0828 191 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 60679969 Common asd putative aspartate-semialdehyde dehydrogenase BF0384 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 60680695 Common - hypothetical protein BF1170 6 None None None 60679902 Common - putative cAMP-binding DNA-binding protein BF0313 19 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 60680323 Common - hypothetical protein BF0769 6 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 60680921 Common - putative phosphoglucomutase BF1409 235 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 60681575 Common - hypothetical protein BF2093 8 None None None 60682577 Common - hypothetical protein BF3108 25 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 60681572 Common - putative lipoate-protein ligase BF2088 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 60680077 Common - putative transport/efflux component protein BF0507 174 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60681209 Common - hypothetical protein BF1715 29 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 60683489 Common - putative beta-galactosidase BF4061 25 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 60683185 Common - pyridoxal phosphate biosynthetic protein PdxJ BF3740 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 60680424 Pathogen - hypothetical protein BF0873 1 None None None 60680606 Pathogen - hypothetical protein BF1069 2 None None None 60681554 Common nqrF Na(+)-translocating NADH-quinone reductase subunit F BF2070 122 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 60680867 Common - putative outer membrane protein BF1351 72 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 60683630 Pathogen - putative DNA-binding protein BF4210 1 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 60681254 Common traA putative conjugative transposon protein BF1762 4 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 60682529 Common - hypothetical protein BF3060 70 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 60681786 Pathogen - hypothetical protein BF2308 1 None None None 60680270 Common - putative TonB-dependent outer membrane receptor protein BF0711 19 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682248 Pathogen - hypothetical protein BF2776 1 None None None 60679786 Common - hypothetical protein BF0191 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 60679635 Pathogen - hypothetical protein BF0038 1 None None None 60681806 Pathogen - hypothetical protein BF2328 1 None None None 60682301 Pathogen - hypothetical protein BF2830 1 None None None 60683145 Pathogen updY putative transcriptional regulator BF3699 2 COG0250 NusG, Transcription antiterminator Transcription 60680660 Common xis putative excisionase BF1133 5 None None None 60680005 Common - hypothetical protein BF0426 154 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 60680768 Common - hypothetical protein BF1248 4 None None None 60681228 Common top1 putative DNA topoisomerase I BF1736 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 60682064 Common exoA exodeoxyribonuclease BF2585 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 60682140 Common - hypothetical protein BF2664 9 None None None 60682470 Pathogen - hypothetical protein BF3000 1 None None None 60680554 Common rmlA2 glucose-1-phosphate thymidyl transferase BF1011 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 60681130 Common - putative 2-oxoisovalerate dehydrogenase, alpha and beta subunits BF1636 179 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 60680670 Pathogen - putative transmembrane protein BF1144 2 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 60680973 Common - putative DNA primase BF1470 9 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 60680408 Common - putative TPR-domain protein BF0857 18 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 60682808 Common - putative exported beta-lactamase protein BF3342 136 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 60683717 Common - putative glycosyltransferase BF4305 191 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60681375 Common - hypothetical protein BF1885 13 None None None 60681263 Common traK conserved hypothetical protein found in conjugate transposon BF1771 5 None None None 60682364 Pathogen - hypothetical protein BF2894 1 None None None 60681332 Common - putative type I restriction-modification system specificity system, partial BF1841 27 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 60683458 Common - putative sigma(54) modulation protein BF4023 66 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 60681851 Pathogen - hypothetical protein BF2371 1 None None None 60683459 Common - putative site-specific recombinase BF4024 232 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60681065 Common - putative DNTP-hexose dehydratase-epimerase BF1564 210 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60683519 Common - hypothetical protein BF4095 6 None None None 60683042 Common - putative exporte hydrolase BF3591 33 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 60682325 Common dfp DNA/pantothenate metabolism flavoprotein BF2855 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 60683694 Common xerD putative tyrosine recombinase BF4279 229 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60683450 Common rpoB DNA-directed RNA polymerase subunit beta BF4015 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 60680586 Pathogen - hypothetical protein BF1047 1 None None None 60683176 Common - hypothetical protein BF3731 6 None None None 60682550 Common - hypothetical protein BF3081 63 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 60682796 Pathogen - putative lipoprotein BF3328 3 None None None 60683286 Pathogen - hypothetical protein BF3843 1 None None None 60682295 Common - hypothetical protein BF2824 5 None None None 60683212 Common - hypothetical protein BF3767 15 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 60681753 Common - 3-deoxy-manno-octulosonate cytidylyltransferase BF2274 138 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 60682910 Common - cold shock-like protein BF3449 101 COG1278 CspC, Cold shock proteins Transcription 60682617 Common - hypothetical protein BF3148 39 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 60680805 Common - hypothetical protein BF1287 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 60679801 Pathogen - hypothetical protein BF0206 1 None None None 60681356 Pathogen - hypothetical protein BF1865 1 None None None 60682586 Common - putative acetyltransferase membrane protein BF3117 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 60682056 Common - putative DNA recombination-related protein BF2577 130 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 60681984 Common - putative magnesium chelatase BF2504 183 COG0714 COG0714, MoxR-like ATPases General function prediction only 60680179 Pathogen - hypothetical protein BF0615 1 None None None 60683633 Pathogen - hypothetical protein BF4213 2 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 60682501 Common - putative thioesterase BF3031 16 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 60680725 Pathogen - hypothetical protein BF1200 1 None None None 60681326 Pathogen - hypothetical protein BF1834 3 None None None 60680419 Common - putative TonB-linked outer membrane protein BF0868 10 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60683107 Common - putative transport-related, membrane protein BF3658 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 60681935 Common - putative ABC transport system, membrane protein BF2455 62 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 60680215 Pathogen - hypothetical protein BF0656 3 None None None 60681981 Common batA aerotolerance-related membrane protein BF2501 74 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 60681451 Common - putative outer membrane protein BF1962 4 None None None 60683390 Pathogen - hypothetical protein BF3955 1 None None None 60679699 Pathogen - hypothetical protein BF0103 1 None None None 60683188 Pathogen - hypothetical protein BF3742 1 None None None 60681972 Common clpB negative regulator of genetic competence BF2492 225 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 60680593 Common - hypothetical protein BF1054 8 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 60680129 Pathogen - hypothetical protein BF0561 1 None None None 60679873 Common - putative exported glycosylhydrolase BF0280 71 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60682149 Common trpG glutamine amidotransferase BF2674 237 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 60682977 Pathogen - hypothetical protein BF3519 1 None None None 60683609 Pathogen - hypothetical protein BF4188 1 None None None 60681402 Common wcgV putative LPS biosynthesis related glycosyltransferase BF1912 130 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60683591 Common bglX periplasmic beta-glucosidase precursor BF4170 145 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 60683140 Common - putative nucleotidyltransferase BF3694 32 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 60679928 Common - putative exported beta-glucosidase BF0339 133 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 60683344 Pathogen - hypothetical protein BF3907 1 None None None 60683637 Common topA putative DNA topoisomerase I BF4217 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 60680064 Pathogen - hypothetical protein BF0494 1 None None None 60683721 Common - putative isomerase BF4309 132 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 60682432 Common - hypothetical protein BF2962 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 60681915 Pathogen - hypothetical protein BF2436 1 None None None 60682375 Common - putative exported hydrolase BF2905 131 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 60682126 Common - putative ABC transport system, membrane protein BF2648 161 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 60683405 Common hutU urocanate hydratase BF3970 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 60679921 Common - hypothetical protein BF0332 2 None None None 60680834 Common - hypothetical protein BF1316 31 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 60681475 Common - hypothetical protein BF1987 3 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 60680782 Common - putative transcriptional regulator, AraC family BF1263 34 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 60680775 Common - hypothetical protein BF1255 38 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 60681979 Common batC aerotolerance-related exported protein BF2499 38 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 60679650 Pathogen - hypothetical protein BF0053 1 None None None 60682135 Common carA carbamoyl phosphate synthase small subunit BF2658 233 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 60680635 Common - hypothetical protein BF1104 4 None None None 60680853 Common - putative TonB dependent outer membrane protein BF1336 23 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680400 Pathogen - hypothetical protein BF0849 3 None None None 60683727 Common - putative transmembrane AcrB/D/F-family transporter BF4315 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60680006 Common - putative UDP-2,3-diacylglucosamine hydrolase BF0427 84 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 60681686 Common - putative two-component system, response regulator BF2207 187 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 60682790 Pathogen - hypothetical protein BF3322 3 None None None 60682873 Common - putative regulatory protein BF3411 38 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60680188 Pathogen - hypothetical protein BF0625 2 None None None 60680289 Common - putative capsular polysaccharide biosynthesis protein BF0733 136 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60682063 Common - hypothetical protein BF2584 130 COG0432 COG0432, Uncharacterized conserved protein Function unknown 60680275 Pathogen - possible oxidoreductase BF0716 2 None None None 60680521 Common - putative RNA polymerase ECF-type sigma factor BF0975 117 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60681156 Common - putative transmembrane glucose/galactose transporter BF1662 54 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 60680264 Common - putative transmembrane Mg2+ transporter BF0705 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 60681296 Common - putative TonB-dependent outer membrane receptor protein BF1804 19 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60682900 Common - hypothetical protein BF3439 16 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 60681158 Common - putative mannose-6-phosphate isomerase BF1664 54 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 60683482 Common - putative transmembrane sugar transporter BF4054 161 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 60679934 Common - hypothetical protein BF0345 64 COG3943 COG3943, Virulence protein General function prediction only 60680037 Pathogen - hypothetical protein BF0463 1 None None None 60682045 Common - hypothetical protein BF2565 2 None None None 60682810 Common - hypothetical protein BF3345 39 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 60681739 Common - putative flavoredoxin BF2260 90 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 60683057 Common asnA asparagine synthetase AsnA BF3607 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 60682129 Common - putative ABC transport system, lipoprotein BF2651 128 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 60679634 Pathogen - hypothetical protein BF0037 2 None None None 60682522 Common - putative two-component system sensor histidine kinase BF3053 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60683318 Common - hypothetical protein BF3881 4 None None None 60680714 Common dnaK molecular chaperone DnaK BF1189 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 60683472 Common - anaerobic C4-dicarboxylate transporter BF4038 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 60682168 Common - putative exported methylamine utilization protein BF2695 97 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 60681676 Common - hypothetical protein BF2197 27 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 60681902 Pathogen - hypothetical protein BF2423 1 None None None 60682566 Common - hypothetical protein BF3097 10 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60679808 Common fucA putative aldolase BF0213 118 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 60680124 Common radA DNA repair protein RadA BF0555 223 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 60683478 Common tnpB putative IstB/TnpB insertion sequence IS21-like protein BF4049 91 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 60682462 Pathogen - hypothetical protein BF2992 1 None None None 60683751 Common sdhA succinate dehydrogenase flavoprotein subunit BF4340 225 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 60683764 Common - putative TIM-barrel protein, possible dihydrouridine synthase BF4353 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 60679773 Common - putative 3-oxoacyl-[acyl-carrier-protein] synthase II BF0178 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 60682237 Common - putative tRNA processing ribonuclease BF2765 142 COG1295 Rbn, Predicted membrane protein Function unknown 60683732 Common - hypothetical protein BF4320 22 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 60681470 Common - putative MarR-family regulatory protein BF1982 67 COG1846 MarR, Transcriptional regulators Transcription 60681304 Common - putative lipoprotein BF1812 15 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 60683170 Common - hypothetical protein BF3725 39 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60680561 Pathogen wzy2 putative polysaccharide polymerase BF1018 1 None None None 60681085 Common - hypothetical protein BF1588 5 None None None 60681667 Pathogen - hypothetical protein BF2188 1 None None None 60680388 Common - hypothetical protein BF0837 49 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 60682268 Common - putative glycosyltransferase BF2797 200 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60680187 Common - possible Hsp-70 cofactor BF0624 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60680244 Common - putative RNA polymerase ECF-type sigma factor BF0685 131 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60680287 Pathogen upgY putative transcriptional regulator BF0731 2 None None None 60679781 Common - putative glycosyltransferase BF0186 97 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60682013 Common - putative cobalamin adenosyltransferase BF2533 130 COG2096 COG2096, Uncharacterized conserved protein Function unknown 60682339 Pathogen - putative lipoprotein BF2869 1 None None None 60681882 Pathogen - hypothetical protein BF2403 1 None None None 60679740 Common - hypothetical protein BF0144 28 None None None 60683257 Pathogen - hypothetical protein BF3813 2 None None None 60683223 Pathogen - hypothetical protein BF3778 2 None None None 60680896 Common - putative lactoylglutathione lyase BF1382 85 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 60681131 Common - flavodoxin FldA BF1637 68 COG0716 FldA, Flavodoxins Energy production and conversion 60681033 Common - hypothetical protein BF1532 43 None None None 60681058 Common - putative glucosyltransferase BF1557 35 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 60683240 Common - hypothetical protein BF3795 79 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 60681095 Common - putative chondroitinase AC precursor BF1599 14 None None None 60683068 Common - putative oxidase BF3618 92 COG0778 NfnB, Nitroreductase Energy production and conversion 60681284 Pathogen - hypothetical protein BF1792 1 None None None 60682661 Common - putative transport-related membrane protein BF3192 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 60683389 Common - hypothetical protein BF3954 21 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 60682509 Common metH putative 5-methyltetrahydrofolate--homocysteine methyltransferase BF3039 181 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 60680563 Common wcfF putative UDP-glucose-6 dehydrogenase BF1020 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 60682591 Common - hypothetical protein BF3122 30 COG5495 COG5495, Uncharacterized conserved protein Function unknown 60679838 Common - hypothetical protein BF0245 5 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 60680494 Pathogen - hypothetical protein BF0946 2 None None None 60679692 Common purD putative phosphoribosylamine--glycine ligase BF0096 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 60679855 Common mraZ hypothetical protein BF0262 130 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 60679879 Common - hypothetical protein BF0286 3 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 60679662 Common ftsX putative cell division protein BF0066 110 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 60682954 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase BF3495 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 60682238 Common - putative nitroreductase BF2766 134 COG0778 NfnB, Nitroreductase Energy production and conversion 60679963 Common - possible exported xanthan lyase/N-acetylmuramoyl-L-alanine amidase BF0377 5 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 60683317 Pathogen - hypothetical protein BF3880 1 None None None 60681704 Common - putative RNA-binding protein BF2225 66 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 60681212 Common - hypothetical protein BF1720 6 None None None 60679827 Common - putative exported alpha-galactosidase BF0233 45 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 60682491 Common - putative peptidyl-dipeptidase BF3021 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 60681123 Pathogen - hypothetical protein BF1627 1 None None None 60682690 Pathogen - hypothetical protein BF3221 1 None None None 60681698 Common - hypothetical protein BF2219 36 COG0657 Aes, Esterase/lipase Lipid metabolism 60680810 Common - hypothetical protein BF1292 9 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 60680384 Common - possible phosphoribosylformylglycinamidine cyclo-ligase BF0833 226 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 60682784 Common - hypothetical protein BF3316 42 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 60681454 Common - hypothetical protein BF1965 6 None None None 60680347 Pathogen - hypothetical protein BF0793 1 None None None 60682388 Common - hypothetical protein BF2918 18 COG1700 COG1700, Uncharacterized conserved protein Function unknown 60682046 Common - hypothetical protein BF2566 3 None None None 60683584 Common purE putative transmembrane phosphoribosylaminoimidazole carboxylase BF4163 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 60681963 Common pyrD1 putative dihydroorotate dehydrogenase, catalytic subunit BF2483 231 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 60683267 Pathogen - hypothetical protein BF3824 1 None None None 60682865 Pathogen - hypothetical protein BF3403 3 None None None 60681118 Common - hypothetical protein BF1622 4 None None None 60681646 Common - putative exported membrane protein BF2167 2 None None None 60681816 Common - putative hydrolase BF2338 147 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 60680847 Pathogen - hypothetical protein BF1330 1 None None None 60681266 Common traM conserved protein found in conjugate transposon BF1774 4 None None None 60682826 Pathogen - putative lipoprotein BF3362 2 None None None 60682797 Pathogen - hypothetical protein BF3330 1 None None None 60680078 Common - putative ATP-binding component of ABC transporter BF0509 177 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60680304 Common - putative UDP-galactose phosphate transferase BF0749 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 60682480 Common - hypothetical protein BF3010 21 None None None 60679613 Common - putative arylsulfatase precursor BF0016 86 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60681952 Pathogen - hypothetical protein BF2472 1 None None None 60683525 Pathogen - hypothetical protein BF4101 1 None None None 60680232 Pathogen - putative transmembrane protein BF0673 1 None None None 60682601 Common - hypothetical protein BF3132 18 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 60682458 Common - hypothetical protein BF2988 5 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 60679823 Common - putative outer membrane protein BF0229 11 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680823 Common menE putative O-succinylbenzoate--CoA ligase BF1305 181 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 60680619 Common - hypothetical protein BF1083 30 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 60679882 Common - putative lipoprotein BF0289 3 None None None 60681192 Common - putative ferredoxin BF1698 16 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 60679685 Pathogen - hypothetical protein BF0089 1 None None None 60682610 Common - hypothetical protein BF3141 32 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 60682551 Common tal putative translaldolase BF3082 155 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 60683597 Pathogen - hypothetical protein BF4176 1 None None None 60681766 Pathogen - hypothetical protein BF2288 1 None None None 60681202 Common - hypothetical protein BF1708 8 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 60681618 Common - flavodoxin BF2139 32 COG0716 FldA, Flavodoxins Energy production and conversion 60681869 Common - putative phosphoserine phosphatase BF2389 158 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 60681227 Pathogen - hypothetical protein BF1735 1 None None None 60682039 Common thiG thiazole synthase BF2559 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 60683461 Common - putative peptidase BF4027 206 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 60683703 Pathogen - hypothetical protein BF4288 2 None None None 60681691 Common - putative ABC transport system, membrane protein BF2212 13 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 60682082 Common - putative LPS biosynthesis-related sugar-phosphate nucleotidyltransferase BF2603 180 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 60680130 Common - putative transmembrane protein BF0562 65 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 60680463 Common - putative anti-sigma factor BF0914 33 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60681769 Pathogen - hypothetical protein BF2291 1 None None None 60683547 Common - putative Hit-family protein BF4126 195 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 60681841 Common rbp RNA binding protein BF2361 66 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 60680143 Common - putative glycosyl hydrolase/xylanase BF0575 41 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 60683356 Common - putative ATP-binding component of ABC transporter BF3919 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 60683058 Common ung uracil-DNA glycosylase BF3608 130 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 60680219 Pathogen - putative transmembrane protein BF0660 2 COG3947 COG3947, Response regulator containing CheY-like receiver and SARP domains Signal transduction mechanisms 60682196 Common - putative two-component system histidne kinase/reponse regulator fusion protein BF2723 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60681391 Pathogen wcfV hypothetical protein BF1901 1 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60680319 Common - putative mannanase BF0764 13 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 60680331 Common - possible endoribonuclease BF0777 73 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 60680994 Common - conserved hypothetical TraM-like protein found in conjugate transposon BF1492 5 None None None 60681172 Common - possible sulfotransferase BF1678 14 None None None 60679817 Common - putative ABC transporter, ATP-binding protein BF0223 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 60680090 Pathogen - hypothetical protein BF0521 2 None None None 60681089 Common - hypothetical protein BF1593 6 None None None 60681524 Pathogen - putative transmembrane protein BF2038 1 None None None 60681533 Common - putative transmembrane glycosyltransferase BF2048 95 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60682175 Common - hypothetical protein BF2702 58 COG2985 COG2985, Predicted permease General function prediction only 60680760 Pathogen - conserved hypothetical protein found on conjugate transposon BF1240 2 None None None 60680819 Common menD putative menaquinone biosynthesis protein BF1301 87 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 60682923 Common - hypothetical protein BF3462 12 COG0778 NfnB, Nitroreductase Energy production and conversion 60681637 Pathogen - hypothetical protein BF2158 1 None None None 60683507 Common - hypothetical protein BF4083 5 None None None 60681219 Common - putative AraC family transcriptional regulator BF1727 65 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60679872 Common - putative glycosylhydrolase BF0279 5 COG4833 COG4833, Predicted glycosyl hydrolase Carbohydrate transport and metabolism 60681875 Pathogen - hypothetical protein BF2395 1 None None None 60683399 Common - putative outer membrane efflux protein BF3964 117 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60681055 Common - putative nucleotide-sugar dehydrogenase BF1554 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 60681877 Pathogen - hypothetical protein BF2397 2 None None None 60682500 Common hisG ATP phosphoribosyltransferase BF3030 213 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 60683778 Common - prolipoprotein diacylglyceryl transferase BF4367 199 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 60683545 Common - hypothetical protein BF4124 15 None None None 60680864 Common - putative transmembrane protein BF1348 4 None None None 60682257 Pathogen - hypothetical protein BF2786 3 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60682983 Common - putative AsnC family regulatory protein BF3525 157 COG1522 Lrp, Transcriptional regulators Transcription 60681836 Common - xylose isomerase BF2356 68 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 60683498 Common - hypothetical protein BF4074 38 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 60680978 Pathogen - hypothetical protein BF1476 1 None None None 60681025 Common - hypothetical protein BF1524 9 None None None 60683325 Common - putative exported peptidyl-prolyl cis-trans isomerase BF3888 125 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 60683665 Common - hypothetical protein BF4247 4 None None None 60680307 Common - putative DegT/DnrJ/EryC1/StrS family aminotransferase protein BF0752 191 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 60680947 Common - putative ATP-binding component of ABC transporter BF1438 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 60680933 Common - putative pyridine nucleotide-disulfide oxidoreductase BF1424 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 60682682 Pathogen - hypothetical protein BF3213 1 None None None 60683441 Common rpsG 30S ribosomal protein S7 BF4006 230 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 60680549 Common - putative YjeF-related sugar kinase BF1005 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 60682807 Common - hypothetical protein BF3340 21 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 60682333 Common - putative epimerase BF2863 151 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60680362 Common - putative alpha-L-fucosidase BF0810 33 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 60681711 Common - putative ATP synthase B chain BF2232 141 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 60683559 Common - putative phosphate acetyl/butyryltransferase BF4138 136 COG0280 Pta, Phosphotransacetylase Energy production and conversion 60681718 Common - putative cation efflux-related lipoprotein BF2239 154 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60682166 Common - hypothetical protein BF2693 6 COG2259 COG2259, Predicted membrane protein Function unknown 60683423 Common rplF 50S ribosomal protein L6 BF3988 219 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 60682909 Common - hypothetical protein BF3448 20 COG3016 PhuW, Uncharacterized iron-regulated protein Function unknown 60680322 Common - putative B12-binding methyltransferase BF0768 174 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 60681271 Pathogen - hypothetical protein BF1779 1 None None None 60680769 Common - putative mobilisation protein BF1249 14 None None None 60681464 Pathogen - hypothetical protein BF1976 2 None None None 60679896 Pathogen - conserved hypothetical lipoprotein BF0306 2 None None None 60682404 Common - hypothetical protein BF2934 27 COG2388 COG2388, Predicted acetyltransferase General function prediction only 60679856 Pathogen - hypothetical protein BF0263 3 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60683561 Common - putative muramoyltetrapeptide carboxypeptidase BF4140 86 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 60679927 Common - hypothetical protein BF0338 22 COG5368 COG5368, Uncharacterized protein conserved in bacteria Function unknown 60681335 Pathogen - hypothetical protein BF1844 1 None None None 60680677 Pathogen - hypothetical protein BF1151 1 None None None 60680027 Common uppS putative undecaprenyl pyrophosphate synthetase BF0450 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 60681248 Pathogen - hypothetical protein BF1756 1 None None None 60683746 Common coaD phosphopantetheine adenylyltransferase BF4334 210 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 60682479 Common - putative regulatory protein BF3009 94 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 60681727 Common - putative iron transport related ATP-binding protein BF2248 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 60680507 Common - ribonuclease Z BF0960 123 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 60680667 Common - putative exonuclease BF1141 87 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 60681553 Common nqrE Na(+)-translocating NADH-quinone reductase subunit E BF2069 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 60681101 Common - putative two-component system sensor histidine kinase protein BF1605 222 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 60682341 Pathogen - putative lipoprotein BF2871 3 None None None 60680117 Common metA homoserine O-succinyltransferase BF0548 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 60683347 Common - hypothetical protein BF3910 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 60683367 Pathogen - hypothetical protein BF3930 1 None None None 60683656 Pathogen - hypothetical protein BF4236 1 None None None 60683161 Common - putative aminotransferase BF3716 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 60681778 Pathogen - hypothetical protein BF2300 1 None None None 60681709 Common - putative ATP synthase A chain BF2230 184 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 60682065 Common - putative manganese transport-related membrane protein BF2586 112 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 60680432 Common - putative carboxy-terminal protease BF0881 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 60679707 Common uvrC putative excinuclease UvrC protein BF0111 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 60681251 Common - hypothetical protein BF1759 16 None None None 60680597 Common - putative modification enzyme of type III restriction-modification system BF1058 88 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 60682691 Common groEL chaperonin GroEL BF3222 245 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 60680971 Common - putative bacteriophage-related replication protein BF1468 6 None None None 60681421 Common - putative transmembrane protein BF1932 102 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 60680258 Common - putative lipid-A-disaccharide synthase BF0699 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 60679640 Pathogen - hypothetical protein BF0043 1 None None None 60680626 Pathogen - hypothetical protein BF1095 1 None None None 60683435 Common rplB 50S ribosomal protein L2 BF4000 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 60681653 Common - putative AraC-family transcriptional regulator BF2174 66 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60682939 Common - hypothetical protein BF3479 2 None None None 60680581 Pathogen - hypothetical protein BF1040 1 None None None 60682739 Pathogen - hypothetical protein BF3269 1 None None None 60683649 Pathogen - hypothetical protein BF4229 2 None None None 60681900 Pathogen - hypothetical protein BF2421 2 None None None 60682759 Common - hypothetical protein BF3291 2 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 60679997 Common - putative LrgB family transmembrane protein BF0417 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 60682541 Common - putative septum formation initiator-related protein BF3072 5 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 60680541 Common - putative 4-hydroxythreonine-4-phosphate dehydrogenase BF0997 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 60681515 Pathogen - hypothetical protein BF2027 1 COG1309 AcrR, Transcriptional regulator Transcription 60682302 Pathogen - hypothetical protein BF2831 2 None None None 60680952 Common - putative ABC transporter permease component BF1446 4 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60683538 Common - 1-deoxy-D-xylulose-5-phosphate synthase BF4114 202 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 60682090 Pathogen - putative lipoprotein BF2611 2 None None None 60680004 Common - putative alkaline phosphatase BF0425 82 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 60682445 Common - putative RNA polymerase sigma factor BF2975 112 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60679601 Common - putative sugar transferase BF0004 188 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60679761 Pathogen - hypothetical protein BF0166 1 None None None 60681014 Common - putative outer membrane protein BF1512 28 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60682003 Common - putative histidinol-phosphate aminotransferase BF2523 235 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 60679983 Pathogen - hypothetical protein BF0400 1 None None None 60680112 Common - putative permease BF0543 77 COG0795 COG0795, Predicted permeases General function prediction only 60681408 Common gnd 6-phosphogluconate dehydrogenase BF1919 159 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 60683137 Common - hypothetical protein BF3691 2 None None None 60679728 Common - putative transmembrane protein BF0132 77 COG2962 RarD, Predicted permeases General function prediction only 60682103 Common pyrG CTP synthetase BF2624 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 60680045 Pathogen - hypothetical protein BF0472 1 None None None 60682028 Common - putative bifunctional CbiE/CbiT cobalamin biosynthesis protein BF2548 98 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 60680739 Common tdcG putative L-serine dehydratase BF1216 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 60681047 Pathogen - hypothetical protein BF1546 1 None None None 60682420 Common - putative acyltransferase BF2950 40 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 60683386 Pathogen - putative transmembrane protein BF3949 1 None None None 60682689 Common - hypothetical protein BF3220 2 None None None 60683562 Common - hypothetical protein BF4141 17 COG2234 Iap, Predicted aminopeptidases General function prediction only 60682548 Common pepD putative aminoacyl-histidine dipeptidase BF3079 59 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 60683339 Common engA GTP-binding protein EngA BF3902 237 COG1160 COG1160, Predicted GTPases General function prediction only 60681145 Common - putative solute-binding protein precursor BF1651 118 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 60683049 Pathogen - hypothetical protein BF3598 1 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 60683074 Common mgsA methylglyoxal synthase BF3624 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 60683569 Common ribF putative riboflavin biosynthesis protein RibF BF4147 211 COG0196 RibF, FAD synthase Coenzyme metabolism 60681006 Common - hypothetical protein BF1504 5 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 60682019 Common - putative iron transport-related exported protein BF2539 124 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60682975 Common - hypothetical protein BF3517 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 60679656 Pathogen - hypothetical protein BF0060 1 None None None 60681363 Common - putative two-component histidine sensor kinase BF1872 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60683434 Common rpsS 30S ribosomal protein S19 BF3999 241 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 60681387 Common aepX putative LPS biosynthesis related phosphoenolpyruvate phosphomutase BF1897 125 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 60682862 Common - putative 6-pyruvoyl tetrahydropterin synthase BF3400 96 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 60681359 Pathogen - hypothetical protein BF1868 1 None None None 60682705 Common - hypothetical protein BF3236 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 60683007 Common - putative acetohydroxyacid synthase small subunit BF3549 93 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 60683119 Common - hypothetical protein BF3670 76 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 60680877 Common - hypothetical protein BF1361 3 None None None 60682743 Common - putative tetraacyldisaccharide kinase (lipid A biosynthesis) related protein BF3273 128 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 60680704 Pathogen - hypothetical protein BF1179 1 None None None 60682071 Common - putative LPS biosynthesis related DNTP-hexose dehydratase-epimerase BF2592 215 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60683133 Common - putative glycosyltransferase protein BF3687 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60682254 Common - putative EPS related membrane protein BF2783 57 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 60683219 Common xseA exodeoxyribonuclease VII large subunit BF3774 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 60680794 Common - putative cNMP and DNA binding protein, possible regulator BF1275 15 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 60683372 Common - putative transmembrane protein BF3935 7 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 60683380 Common - hypothetical protein BF3943 77 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 60680137 Common - putative anti-sigma factor BF0569 36 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60681170 Common cysD sulfate adenylyltransferase subunit 2 BF1676 135 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 60683110 Common - putative response regulator BF3661 104 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 60679622 Common - putative CoA transferase BF0025 97 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 60680429 Common - hypothetical protein BF0878 7 COG5512 COG5512, Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives General function prediction only 60681862 Common uxaC glucuronate isomerase BF2382 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 60683024 Common - hypothetical protein BF3569 35 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 60680487 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase BF0938 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 60680852 Common - putative peptidase BF1335 104 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 60682452 Common - putative exonuclease BF2982 94 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 60682156 Common - putative response regulator BF2682 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 60679891 Common - putative aldose 1-epimerase BF0300 93 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 60682191 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase BF2718 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 60679722 Common - hypothetical protein BF0126 27 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 60681898 Common - putative proteinase BF2419 140 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 60682852 Common - hypothetical protein BF3390 47 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 60683689 Common - putative ribosome-binding factor A BF4274 100 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 60681642 Pathogen - putative lipoprotein BF2163 1 None None None 60682836 Common - hypothetical protein BF3373 9 None None None 60683526 Common - putative two-component sensor histidine kinase transcriptional regulator BF4102 82 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 60681316 Common - hypothetical protein BF1824 4 None None None 60682776 Common - putative membrane attached hydrolase BF3308 6 COG4833 COG4833, Predicted glycosyl hydrolase Carbohydrate transport and metabolism 60679844 Common ftsA putative cell division protein BF0251 178 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 60681826 Pathogen - hypothetical protein BF2347A 1 None None None 60682631 Common - putative carbon starvation-related membrane protein BF3162 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 60679700 Common polA putative DNA polymerase I BF0104 217 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 60683236 Common - putative ribosomal large subunit pseudouridine synthase BF3791 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 60680107 Pathogen frrI hypothetical protein BF0538 1 None None None 60681128 Common lplA putative lipoate-protein ligase BF1632 60 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 60682349 Pathogen - hypothetical protein BF2879 1 None None None 60680578 Common - putative M23/M37-family peptidase BF1036 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 60681835 Common - putative xylulose kinase BF2355 174 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 60681444 Common - putative pyruvate carboxylase biotin-containing subunit BF1955 145 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 60679792 Common - putative acetylglutamate kinase BF0197 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 60683419 Common rplO 50S ribosomal protein L15 BF3984 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 60682226 Common - putative two component system histidine kinase BF2754 195 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60682730 Common - hypothetical protein BF3260 60 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 60682819 Common - hypothetical protein BF3354 5 None None None 161723189 Common trpB tryptophan synthase subunit beta BF1192 225 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 60682848 Common - hypothetical protein BF3386 19 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 60683733 Pathogen - hypothetical protein BF4321 1 None None None 60681297 Common - hypothetical protein BF1805 3 None None None 60681922 Pathogen - hypothetical protein BF2441 1 None None None 60683531 Common - putative transmembrane protein BF4107 2 None None None 60680749 Pathogen - hypothetical protein BF1226 1 None None None 60679684 Pathogen - hypothetical protein BF0088 1 None None None 60681133 Common - hypothetical protein BF1639 4 None None None 60682141 Common dapF diaminopimelate epimerase BF2665 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 60681585 Common - putative transmembrane protein BF2104 19 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 60680919 Common - putative peptidase BF1407 107 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 60681255 Common traB hypothetical protein BF1763 3 None None None 60680920 Common - putative dipeptidase BF1408 26 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 60682673 Common - putative acyl-CoA dehydrogenase BF3204 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 60680216 Common - putative aminopeptidase BF0657 62 COG2234 Iap, Predicted aminopeptidases General function prediction only 60682576 Common pgk phosphoglycerate kinase BF3107 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 60683189 Pathogen - hypothetical protein BF3743 1 None None None 60683574 Common - putative phosphoribulose/uridine kinase BF4152 180 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 60680434 Pathogen - hypothetical protein BF0883 1 None None None 60681341 Pathogen - hypothetical protein BF1850 1 None None None 60680197 Pathogen - hypothetical protein BF0636 3 None None None 60682991 Common - putative isoprenoid biosynthesis related protein BF3533 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 60679812 Common nusA transcription elongation factor NusA BF0218 223 COG0195 NusA, Transcription elongation factor Transcription 60679603 Common - hypothetical protein BF0006 2 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 60681809 Pathogen - putative DNA binding protein BF2330 1 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 60683417 Common map putative methionine aminopeptidase BF3982 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 60681966 Common dapA2 putative dihydrodipicolinate synthase BF2486 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 60682185 Common - hypothetical protein BF2712 8 COG4744 COG4744, Uncharacterized conserved protein Function unknown 60679762 Common - hypothetical Kelch-like protein BF0167 3 None None None 60682240 Common - putative phosphate transport chemotaxis-related protein BF2768 189 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 60681068 Pathogen - hypothetical protein BF1567 1 None None None 60681989 Common rpmG 50S ribosomal protein L33 BF2509 48 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 60681253 Pathogen - hypothetical protein BF1761 1 None None None 60681502 Common - hypothetical protein BF2014 2 None None None 60683146 Pathogen - hypothetical protein BF3700 1 None None None 60681925 Common - putative integrase BF2444 7 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60679794 Pathogen - hypothetical protein BF0199 2 None None None 60680726 Common - putative anti-sigma factor BF1203 25 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60680851 Common - putative transmembrane CorC/HlyC family transporter BF1334 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 60682208 Common - putative ABC transport system, lipoprotein BF2735 129 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 60681556 Common serC phosphoserine aminotransferase BF2072 136 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 60680055 Common - putative acetyltransferase BF0482 6 None None None 60681347 Pathogen - hypothetical protein BF1856 1 None None None 60680488 Pathogen - putative ATP/GTP-binding transmembrane protein BF0939 1 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 60682275 Common - putative glycosyltransferase BF2804 206 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 60679839 Common - DNA gyrase subunit B BF0246 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 60683677 Common rpsO 30S ribosomal protein S15 BF4259 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 60680108 Common - hypothetical protein BF0539 8 None None None 60683023 Common - putative exported phosphatase BF3568 5 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 60679890 Common - hypothetical protein BF0299 19 COG3538 COG3538, Uncharacterized conserved protein Function unknown 60683067 Common dnaA chromosomal replication initiation protein BF3617 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 60680713 Common - putative transcriptional regulator BF1188 2 COG0250 NusG, Transcription antiterminator Transcription 60682249 Common tpx putative thiol peroxidase BF2777 127 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 60682809 Common impDH inositol-5-monophosphate dehydrogenase BF3343 234 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 60683222 Pathogen - hypothetical protein BF3777 1 None None None 60682798 Common - putative AraC-family regulatory protein BF3331 5 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60683184 Common - putative transport related membrane protein BF3739 139 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 60680030 Common - putative protoporphyrinogen oxidase BF0453 217 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 60683655 Common - putative bacteriophage integrase BF4235 19 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60682533 Common - hypothetical protein BF3064 7 COG3295 COG3295, Uncharacterized protein conserved in bacteria Function unknown 60683571 Common - putative transmembrane calcium-transporting ATPase BF4149 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 60683197 Common - putative antibiotic resistance-related regulatory protein BF3751 45 COG3682 COG3682, Predicted transcriptional regulator Transcription 60683709 Common metG methionyl-tRNA synthetase BF4297 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60681908 Pathogen - hypothetical protein BF2429 2 None None None 60680737 Common - hypothetical protein BF1214 5 None None None 60681307 Common bgaA beta-galactosidase BF1815 72 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 60682219 Common - V-type ATP synthase subunit B BF2746 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 60680156 Common - putative surface membrane protein BF0590 25 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680513 Common valS valyl-tRNA synthetase BF0966 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 60682965 Common ppk polyphosphate kinase BF3507 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 60682114 Common - conserved exported hypothetical protein BF2635 44 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 60681748 Common - putative lipoprotein BF2269 5 None None None 60683177 Common - putative exported peptidase BF3732 187 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 60682165 Common - hypothetical membrane protein BF2692 2 None None None 60682092 Common galE UDP-glucose 4-epimerase BF2613 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 60681199 Common - putative surface antigen BF1705 16 None None None 60681384 Pathogen upbZ putative LPS biosynthesis related transcriptional regulatory protein BF1894 1 None None None 60681505 Pathogen - hypothetical protein BF2017 1 None None None 60682383 Common - hypothetical protein BF2913 26 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 60679858 Common sigE putative extracytoplasmic function alternative sigma factor BF0265 167 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60683375 Pathogen - hypothetical protein BF3938 1 None None None 60681497 Pathogen - putative transmembrane protein BF2009 1 None None None 60682644 Common - putative fructokinase BF3175 138 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 60683729 Pathogen - hypothetical protein BF4317 1 None None None 60682117 Common - hypothetical protein BF2638 7 None None None 60680397 Common - hypothetical protein BF0846 16 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 60680806 Common purF putative amidophosphoribosyltransferase precursor BF1288 227 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 60679832 Common rnhB ribonuclease HII BF0239 229 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 60683752 Common - succinate dehydrogenase/fumarate reductase iron-sulfur subunit BF4341 65 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 60679968 Common - hypothetical protein BF0382 6 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 60681186 Pathogen - hypothetical protein BF1692 2 None None None 60683610 Common - putative alpha-galactosidase/melibiase BF4189 14 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 60682354 Common ftnA ferritin A BF2884 84 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 60682676 Common - putative chaperone BF3207 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 60682558 Common - putative two-component system histidine kinase/response regulator fusion protein BF3089 91 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60682058 Common - putative Na+/H+ antiporter BF2579 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 60680118 Common - putative protease BF0549 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 60683412 Common rpsD 30S ribosomal protein S4 BF3977 226 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 60679949 Common nrfA cytochrome c nitrite reductase BF0361 40 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 60681990 Common rpmB 50S ribosomal protein L28 BF2510 124 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 60679658 Pathogen - hypothetical protein BF0062 1 None None None 60683086 Common - elongation factor G BF3636 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 60680233 Common - hypothetical protein BF0674 8 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682717 Common - putative AraC-family regulatory protein BF3248 49 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60681157 Common - putative aldose 1-epimerase precursor BF1663 90 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 60682761 Common - hypothetical protein BF3293 22 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 60682854 Common - hypothetical protein BF3392 21 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 60679769 Common - putative tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase BF0174 213 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 60679971 Common - putative ThiF family protein BF0386 173 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 60680479 Common rplU 50S ribosomal protein L21 BF0930 211 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 60681386 Common wcfU putative glucose-1-P-cytidylyltransferase BF1896 99 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 60679959 Common - hypothetical protein BF0371 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 60680278 Common - putative transmembrane permease BF0719 147 COG2962 RarD, Predicted permeases General function prediction only 60681842 Common ccp cytochrome-C peroxidase BF2362 93 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 60683150 Common - putative single-stranded-DNA-specific exonuclease BF3705 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 60680098 Common kdpB putative potassium-transporting ATPase B chain BF0529 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 60681834 Common - hypothetical protein BF2354 45 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 60680723 Common - putative xylosidase/arabinosidase BF1198 35 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 60680057 Common - putative two-component histidine sensor kinase BF0486 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60679787 Common - putative shikimate kinase BF0192 199 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 60681955 Common - putative outer membrane exported protein BF2475 136 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60679976 Common murF putative UDP-N-acetylmuramoyl-tripeptide--D-alanyl-d-alanine ligase BF0391 207 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 60682549 Common - putative conserved exported protein BF3080 18 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 60683465 Common - putative transmembrane HD family protein BF4031 57 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 60682450 Pathogen - hypothetical protein BF2980 1 None None None 60680955 Common - putative outer membrane protein BF1449 10 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60680024 Common - putative outer membrane protein BF0447 10 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 60679846 Common murC UDP-N-acetylmuramate--L-alanine ligase BF0253 209 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 60683306 Pathogen - hypothetical protein BF3864 1 None None None 60680279 Common - putative transmembrane transport protein BF0722 62 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 60680423 Common - possible outer membrane protein BF0872 6 None None None 60679673 Common - hypothetical protein BF0077 186 COG0759 COG0759, Uncharacterized conserved protein Function unknown 60681179 Common - putative bacteriophage integrase BF1685 184 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60682446 Pathogen - hypothetical protein BF2976 1 None None None 60682489 Common - putative iron uptake-related regulatory protein BF3019 128 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 60680835 Common - putative DNA-binding protein BF1317 128 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 60681155 Common galK putative galactokinase BF1661 98 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 60681997 Common - putative exported tricorn protease BF2517 142 COG4946 COG4946, Uncharacterized protein related to the periplasmic component of the Tol biopolymer transport system Function unknown 60682232 Pathogen - hypothetical protein BF2760 1 None None None 60683165 Common - putative DNA primase BF3720 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 60683537 Common - putative AraC-family transcriptional regulator BF4113 55 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60683726 Common - putative outer membrane component of efflux transporter BF4314 113 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60682911 Pathogen - hypothetical protein BF3450 1 None None None 60681420 Common - putative two-component system response regulator BF1931 157 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 60679888 Common - putative exported glutaminase BF0297 5 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 60679935 Pathogen - hypothetical protein BF0346 1 None None None 60683056 Common - putative hydrolase BF3606 175 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 60680204 Pathogen - hypothetical protein BF0643 3 None None None 60683599 Common - putative outer membrane protein BF4178 23 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60681201 Common - putative capsule polysaccharide export protein BF1707 94 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 60680263 Common - hypothetical protein BF0704 33 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60680500 Common trxB putative thioredoxin reductase BF0952 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 60683360 Common - hypothetical protein BF3923 33 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 60683509 Pathogen - hypothetical protein BF4085 2 None None None 60682791 Pathogen - hypothetical protein BF3323 1 None None None 60682374 Common - putative methyltransferase BF2904 4 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 60682564 Common - putative exported hydrolase BF3095 60 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60682919 Common - putative LPS biosynthesis related glycosyltransferase BF3458 190 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60680339 Common nuoL putative NADH dehydrogenase chain L BF0785 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 60682032 Common - putative hexokinase BF2552 6 COG5026 COG5026, Hexokinase Carbohydrate transport and metabolism 60680190 Common dinF putative DNA-damage-inducible protein F BF0627 167 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60682896 Pathogen - hypothetical protein BF3434 2 None None None 161723190 Common obgE GTPase ObgE BF1033 249 COG0536 Obg, Predicted GTPase General function prediction only 60680383 Common prfA peptide chain release factor 1 BF0832 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 60681573 Pathogen - hypothetical protein BF2089 1 None None None 60681685 Common - putative two-component system, sensor kinase BF2206 222 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 60681914 Pathogen - hypothetical protein BF2435 1 None None None 60679865 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase BF0272 178 COG0756 Dut, dUTPase Nucleotide transport and metabolism 60682062 Common - hypothetical protein BF2583 18 None None None 60682953 Common rimM 16S rRNA-processing protein BF3494 41 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 60682490 Common - hypothetical protein BF3020 67 COG3152 COG3152, Predicted membrane protein Function unknown 60680785 Common - possible AraC family transcriptional regulator BF1266 88 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60681214 Common - putative outer membrane protein BF1722 38 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680221 Common - hypothetical protein BF0662 4 None None None 60682567 Common - putative anti-sigma factor BF3098 29 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60683116 Common - putative glycosyl hydrolase BF3667 26 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 60681787 Pathogen - hypothetical protein BF2309 1 None None None 60682167 Common - putative exported thioredoxin BF2694 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 60682512 Pathogen - putative lipoprotein BF3042 1 None None None 60682128 Common - putative BAC transport system, two-fused ATP-binding domains protein BF2650 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 60680931 Common - putative NADH pyrophosphatase BF1422 120 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 60682621 Common - hypothetical protein BF3152 53 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60681034 Common - putative integrase BF1533 10 None None None 60681740 Common pyrI aspartate carbamoyltransferase regulatory subunit BF2261 64 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 60683471 Common aspA aspartate ammonia-lyase BF4037 220 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 60679915 Common - putative TonB-dependent receptor exported protein BF0326 8 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682132 Common - putative AraC-family transcriptional regulator BF2655 72 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60682051 Pathogen - putative lipoprotein BF2571 1 None None None 60682153 Common trpA tryptophan synthase subunit alpha BF2678 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 60683511 Common - hypothetical protein BF4087 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 60683634 Common - putative MutT/NUDIX family protein BF4214 25 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 60680306 Common - putative FIC family protein BF0751 55 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 60682521 Common rho transcription termination factor Rho BF3052 214 COG1158 Rho, Transcription termination factor Transcription 60683477 Common - putative two-component system sensor histidine kinase/response regulator fusion protein BF4048 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60681471 Common - putative protoporphyrinogen oxidase BF1983 71 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 60679956 Common - hypothetical protein BF0368 10 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 60680266 Common - putative transmembrane protein BF0707 12 COG0392 COG0392, Predicted integral membrane protein Function unknown 60680036 Common - putative regulatory protein BF0462 3 COG1396 HipB, Predicted transcriptional regulators Transcription 60683720 Common fklB putative FkbP-type 22 kDa peptidyl-prolyl cis-trans isomerase BF4308 141 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 60679920 Common - putative exported hydrolase BF0331 20 None None None 60683406 Pathogen - hypothetical protein BF3971 1 None None None 60683229 Common tsf elongation factor Ts BF3784 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 60681441 Common htpX putative transmembrane protease HtpX homolog BF1952 193 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 60683424 Common rpsH 30S ribosomal protein S8 BF3989 249 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 60679747 Common - conserved hypothetical outer membrane protein BF0151 6 None None None 60682519 Common - putative ribonuclease BF3049 51 COG1295 Rbn, Predicted membrane protein Function unknown 60682599 Common bcc putative biotin carboxyl carrier protein BF3130 218 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 60683043 Common mutB methylmalonyl-CoA mutase BF3592 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 60682641 Common opuAA putative glycine betaine transport ATP-binding protein BF3172 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 60682365 Common - hypothetical protein BF2895 21 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 60680938 Pathogen - hypothetical protein BF1429 1 None None None 60680165 Pathogen - hypothetical protein BF0599 4 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 60681357 Pathogen - hypothetical protein BF1866 1 None None None 60681512 Common - hypothetical protein BF2024 2 None None None 60679667 Common - putative 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase (HPPK) BF0071 201 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 60682976 Common - hypothetical protein BF3518 15 None None None 60682585 Common - putative acyl carrier protein BF3116 11 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 60679641 Pathogen - hypothetical protein BF0044 2 None None None 60683747 Common - putative carboxy-terminal processing protease precursor BF4335 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 60682463 Pathogen - hypothetical protein BF2993 2 None None None 60682057 Common - hypothetical protein BF2578 12 None None None 60683757 Common - hypothetical protein BF4346 3 None None None 60679716 Pathogen - hypothetical protein BF0120 1 None None None 60682089 Common - putative terpenoid biosynthesis-related protein BF2610 170 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 60682296 Common - putative racemase BF2825 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 60683002 Common - putative DNA-binding protein BF3544 87 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 60681403 Common wcgW putative LPS biosynthesis related dehydratase BF1913 91 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60681675 Common - putative lipoprotein BF2196 6 None None None 60681261 Common traI conserved protein found in conjugate transposon BF1769 4 None None None 60681790 Pathogen - hypothetical protein BF2312 2 None None None 60681329 Common hsdM putative type I restriction enzyme methylase BF1838 162 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 60682309 Common - putative two-component system, histidine kinase BF2839 207 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60681433 Common - glycerate dehydrogenase BF1944 230 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 60683108 Common - putative lipoprotein BF3659 104 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60681535 Common - putative transmembrane acyltransferase BF2050 78 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 60681491 Common - hypothetical protein BF2003 7 COG3291 COG3291, FOG: PKD repeat General function prediction only 60680330 Common - hypothetical protein BF0776 4 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 60680132 Common - putative nicotinamide mononucleotide transporter BF0564 60 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 60680063 Pathogen - hypothetical protein BF0493 1 None None None 60681144 Common - putative GFO/IDH/MocA-family oxidoreductase BF1650 181 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 60682284 Common - putative transmembrane protein BF2813 6 None None None 60680592 Pathogen - hypothetical protein BF1053 1 None None None 60679706 Common dtd D-tyrosyl-tRNA deacylase BF0110 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 60683625 Pathogen - hypothetical protein BF4205 1 None None None 60681624 Common - putative aldo/keto reductase BF2145 178 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 60679734 Common - putative lysine decarboxylase BF0138 136 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 60681142 Pathogen - hypothetical protein BF1648 2 None None None 60681613 Common - putative aldo/keto reductase BF2134 195 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 60682618 Common - putative glycosyl hydrolase BF3149 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 60683786 Common nadA quinolinate synthetase BF4375 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 60681270 Pathogen - hypothetical protein BF1778 1 None None None 60680178 Common - possible glycosyl transferase BF0614 7 None None None 60680825 Common - putative alpha-glucosidase protein BF1307 18 None None None 60683038 Common - putative peptidase BF3585 160 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 60680885 Common wcfN putative LPS biosynthesis related glycosyltransferase BF1371 56 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 60681982 Common - putative conserved membrane exported protein BF2502 9 None None None 60683603 Common - putative transmembrane sugar transporter BF4182 110 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60680724 Common cepA beta-lactamase BF1199 57 COG2367 PenP, Beta-lactamase class A Defense mechanisms 60681767 Pathogen - hypothetical protein BF2289 1 None None None 60680070 Common - putative outer membrane protein BF0500 6 None None None 60681048 Pathogen - hypothetical protein BF1547 1 None None None 60679881 Common - putative TonB dependent receptor outer membrane protein BF0288 40 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60680878 Pathogen - hypothetical protein BF1362 2 None None None 60683398 Common - putative membrane fusion protein transporter BF3963 173 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60680540 Common - hypothetical protein BF0996 6 None None None 60680639 Pathogen - putative ATP/GTP-binding protein BF1109 1 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 60683497 Pathogen - hypothetical protein BF4073 1 None None None 60682699 Pathogen - hypothetical protein BF3230 3 None None None 60683039 Common - putative exported hydrolase BF3586 53 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 60683462 Common - putative hexapeptide repeat protein BF4028 185 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 60682080 Common - putative LPS biosynthesis related DNTP-hexose dehydratase-epimerase BF2601 200 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 60682698 Common - hypothetical protein BF3229 6 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 60681265 Pathogen - hypothetical protein BF1773 1 None None None 60680164 Common - putative GTP-binding protein BF0598 222 COG2262 HflX, GTPases General function prediction only 60679905 Common - hypothetical protein BF0316 32 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 60679980 Common - putative two-component system sensor histidine kinase BF0395 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 60680222 Common - hypothetical protein BF0663 3 None None None 60680596 Common - putative restriction enzyme of type III restriction-modification system BF1057 46 COG3587 COG3587, Restriction endonuclease Defense mechanisms 60683300 Common - putative acetylornithine aminotransferase BF3858 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 60681269 Pathogen traQ conserved protein found in conjugate transposon BF1777 3 None None None 60679609 Common - hypothetical protein BF0012 5 None None None 60681081 Common - hypothetical protein BF1582 25 COG3391 COG3391, Uncharacterized conserved protein Function unknown 60681591 Common - putative amino acid transferase BF2110 140 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 60683111 Common - putative iron hydrogenase BF3662 87 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 60680405 Pathogen - hypothetical protein BF0854 1 None None None 60682018 Common - hypothetical protein BF2538 57 COG2985 COG2985, Predicted permease General function prediction only 60681404 Common wcgX putative LPS biosynthesis related UndPP-QuiNAc-P-transferase BF1914 137 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 60683393 Common - putative transmembrane polysaccharide modification protein BF3958 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 60682081 Common - putative LPS biosynthesis related DNTP-hexose dehydratase-epimerase BF2602 225 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60681225 Pathogen - hypothetical protein BF1733 1 None None None 60679824 Pathogen - hypothetical protein BF0230 1 None None None 60681946 Common - putative deiminase BF2466 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 60680431 Common - putative 5-formyltetrahydrofolate cyclo-ligase BF0880 174 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 60683508 Pathogen - hypothetical protein BF4084 1 None None None 60681713 Common atpA F0F1 ATP synthase subunit alpha BF2234 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 60681819 Common - hypothetical protein BF2341 133 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 60682982 Common dfrA putative dihydrofolate reductase BF3524 144 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 60680144 Common - hypothetical protein BF0576 5 None None None 60680534 Common - hypothetical protein BF0991 5 None None None 60681868 Common rhlE putative ATP-dependent RNA helicase BF2388 244 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 60681876 Pathogen - hypothetical protein BF2396 1 None None None 60680964 Common - putative type I restriction enzyme specificity protein BF1461 46 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 60682669 Common - putative lipoprotein BF3200 4 None None None 60681410 Common pgl putative 6-phosphogluconolactonase BF1921 123 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 60680131 Common - hypothetical protein BF0563 32 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 60680293 Common - putative polysaccharide transporter/flippase BF0737 85 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 60680647 Common - hypothetical protein BF1118 8 None None None 60683518 Common - possible bacterial surface protein BF4094 15 None None None 60681536 Common - putative glycosyltransferase BF2051 22 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60682253 Common - putative EPS related membrane protein BF2782 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 60680865 Common - putative transmembrane transporter permease protein BF1349 155 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 60682481 Common - hypothetical protein BF3011 21 None None None 60683311 Pathogen - hypothetical protein BF3872 1 None None None 60683777 Common - putative 2-dehydropantoate 2-reductase BF4366 76 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 60683279 Pathogen - hypothetical protein BF3836 2 None None None 60680997 Common - conserved hypothetical TraN-like protein found in conjugate transposon BF1495 5 None None None 60680568 Common wcfK putative epimerase/dehydratase BF1025 111 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 60681970 Common - hypothetical protein BF2490 133 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 60682331 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase BF2861 198 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 60682777 Common - putative acetyltransferase BF3309 132 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 60680907 Common - putative transmembrane protein BF1395 90 COG1738 COG1738, Uncharacterized conserved protein Function unknown 60680091 Pathogen - hypothetical protein BF0522 2 None None None 60681874 Common - hypothetical protein BF2394 101 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 60683714 Pathogen - putative transmembrane protein BF4302 1 None None None 60680911 Pathogen - hypothetical protein BF1399 2 None None None 60683702 Common - putative radical SAM-family protein BF4287 126 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 60683731 Common - putative D-Ala-D-Ala dipeptidase protein BF4319 46 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 60681638 Pathogen - hypothetical protein BF2159 1 None None None 60680579 Common - hypothetical protein BF1037 4 None None None 60680687 Common hslR putative ribosome-associated heat shock protein BF1162 106 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 60680493 Common - putative nucleoside/H+ permease BF0944 35 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 60681472 Common hemN coproporphyrinogen III oxidase BF1984 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 60683171 Common - putative RNA polymerase sigma factor BF3726 42 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60681230 Common xerC putative tyrosine recombinase BF1738 229 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60679962 Common - putative PQQ-binding exported phosphoesterase BF0376 136 COG1520 COG1520, FOG: WD40-like repeat Function unknown 60680611 Common - hypothetical protein BF1074 59 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 60683268 Pathogen - hypothetical protein BF3825 1 None None None 60682332 Pathogen - hypothetical protein BF2862 1 None None None 60682338 Pathogen - putative lipoprotein BF2868 1 None None None 60682540 Common - putative DNA polymerase III BF3071 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 60680060 Common - putative malate dehydrogenase BF0489 196 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 60681283 Common - putative transcriptional regulator BF1791 144 COG1733 COG1733, Predicted transcriptional regulators Transcription 60682590 Common - putative lipopolysaccharide biosynthesis-related protein BF3121 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 60683205 Common - hypothetical protein BF3760 104 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 60679864 Common dgt putative deoxyguanosinetriphosphate triphosphohydrolase BF0271 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 60681883 Pathogen - putative lipoprotein BF2404 1 None None None 60679691 Pathogen - putative transmembrane protein BF0095 2 None None None 60682395 Common - hypothetical protein BF2925 166 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 60679828 Pathogen - putative lipoprotein BF0234 1 None None None 60680123 Common - hypothetical protein BF0554 17 None None None 60680897 Pathogen - hypothetical protein BF1383 2 None None None 60681752 Common - hypothetical protein BF2273 5 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 60680387 Common - hypothetical protein BF0836 86 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 60683258 Pathogen - hypothetical protein BF3814 1 None None None 60681057 Common - putative polysaccharide transporter/flippase BF1556 90 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 60682438 Common - hypothetical protein BF2968 4 None None None 60683132 Common - putative polysaccharide polymerase BF3686 4 None None None 60681242 Pathogen - hypothetical protein BF1750 1 None None None 60680138 Common - hypothetical protein BF0570 18 None None None 60681124 Pathogen - putative ATP/GTP-binding protein BF1628 1 None None None 60680357 Common - putative sulfatase BF0805 94 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 60681598 Pathogen - hypothetical protein BF2117 2 None None None 60683296 Common - hypothetical protein BF3854 3 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60681934 Common - putative ABc transport system, membrane protein BF2454 14 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 60680745 Common - putative anti-restriction protein BF1222 18 COG4734 ArdA, Antirestriction protein General function prediction only 60681086 Common - putative two-component histidine kinase sensor protein BF1589 224 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 60681211 Common - putative outer membrane protein BF1719 34 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60682841 Common - bifunctional methionine sulfoxide reductase A/B protein BF3378 206 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 60683338 Common - putative LuxR-family regulatory protein BF3901 192 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 60680750 Common - hypothetical protein BF1230 16 None None None 60680348 Common - putative potassium uptake protein BF0794 137 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 60682473 Pathogen - putative lipoprotein BF3003 2 None None None 60682047 Common ppdK pyruvate phosphate dikinase BF2567 234 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 60682864 Common - hypothetical protein BF3402 18 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 60683156 Common - putative lipoprotein BF3711 6 None None None 60681690 Common - putative ABC transport system, ATP-binding protein BF2211 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 60683160 Common - putative prefrenate dehydratase BF3715 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 60681645 Common - hypothetical protein BF2166 2 None None None 60683619 Pathogen - hypothetical protein BF4198 1 None None None 60682853 Common - putative cytidylyltransferase BF3391 215 COG4589 COG4589, Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase General function prediction only 60682751 Common - putative transposon-related/mobilisation protein BF3283 5 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 60679661 Common - hypothetical protein BF0065 33 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 60682785 Common - hypothetical protein BF3317 61 COG2030 MaoC, Acyl dehydratase Lipid metabolism 60682038 Common thiE thiamine-phosphate pyrophosphorylase BF2558 206 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 60683093 Common - hypothetical protein BF3642 26 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 60681438 Common - putative transmembrane protein BF1949 132 COG2860 COG2860, Predicted membrane protein Function unknown 60681007 Pathogen - hypothetical protein BF1505 1 None None None 60681279 Pathogen - hypothetical protein BF1787 1 None None None 60682499 Common hisD putative histidinol dehydrogenase BF3029 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 60682664 Common - hypothetical protein BF3195 8 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 60681305 Common nahC beta-N-acetylhexosaminidase BF1813 58 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 60682758 Common - putative AraC-family regulatory protein BF3290 78 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60683194 Pathogen - putative lipoprotein BF3748 1 None None None 60682262 Common - putative transmembrane protein BF2791 7 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 60682742 Common sppA putative protease IV BF3272 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 60683596 Common - hypothetical protein BF4175 2 None None None 60682102 Pathogen - hypothetical protein BF2623 1 None None None 60681710 Pathogen atpE ATP synthase C chain BF2231 1 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 60682736 Common leuC isopropylmalate isomerase large subunit BF3266 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 60680168 Common - putative transmembrane acyl-transferase protein BF0602 19 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 60682421 Common - putative hydrolase BF2951 196 COG0388 COG0388, Predicted amidohydrolase General function prediction only 60682731 Common - putative transport-related, membrane protein BF3261 22 COG3952 COG3952, Predicted membrane protein Function unknown 60680772 Common - hypothetical protein BF1252 44 COG4889 COG4889, Predicted helicase General function prediction only 60682611 Common - hypothetical protein BF3142 55 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 60681861 Common - putative transport-related membrane protein BF2381 73 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 60679648 Pathogen - hypothetical protein BF0051 1 None None None 60679721 Common - putative transmembrane spore maturation-like protein BF0125 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 60683568 Pathogen - hypothetical protein BF4146A 1 None None None 60679994 Pathogen - hypothetical protein BF0414 2 None None None 60680927 Pathogen - hypothetical protein BF1417 1 None None None 60679754 Common - hypothetical protein BF0158 10 None None None 60680311 Common - hypothetical protein BF0756 12 None None None 60680527 Pathogen - hypothetical protein BF0981 1 None None None 60681013 Common - putative outer membrane protein BF1511 5 None None None 60682223 Pathogen - hypothetical protein BF2751 1 None None None 60683030 Common - putative lipoprotein BF3575 5 None None None 60681362 Common - putative RNA-binding protein BF1871 210 COG2183 Tex, Transcriptional accessory protein Transcription 60680464 Pathogen - putative outer membrane protein BF0915 1 None None None 60682027 Common cobJ precorrin-3B C17-methyltransferase BF2547 155 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 60682453 Common - putative phospholipids biosynthesis-related protein BF2983 179 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 60680734 Pathogen - hypothetical protein BF1211 1 None None None 60680824 Common - putative endonuclease/exonuclease/phosphatase family protein BF1306 28 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 60682002 Common - putative cobalamin biosynthesis protein BF2522 149 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 60683073 Common - hypothetical protein BF3623 41 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 60681390 Common wzx putative LPS biosynthesis related flippase BF1900 4 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 60680412 Common - putative cytochrome c binding protein BF0861 4 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 60681692 Common - putative ABC transport system, ATP-binding protein BF2213 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 60682837 Common - hypothetical protein BF3374 84 COG1285 SapB, Uncharacterized membrane protein Function unknown 60683672 Common - hypothetical protein BF4254 2 None None None 60682959 Common nadD nicotinic acid mononucleotide adenyltransferase BF3501 194 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 60683136 Common - putative O-acetyl transferase (capsular polysaccharide synthesis enzyme o-acetyl transferase) BF3690 181 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 60681899 Pathogen - hypothetical protein BF2420 2 None None None 60679795 Pathogen - hypothetical protein BF0200 1 None None None 60680589 Common mmdB putative transmembrane methylmalonyl-CoA/oxaloacetate decarboxylase, beta-subunit BF1050 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 60681641 Pathogen - hypothetical protein BF2162 1 None None None 60683530 Common - putative TonB-dependent outer membrane receptor protein BF4106 124 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 60682818 Common - hypothetical protein BF3353 27 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 60683387 Common - hypothetical protein BF3950 21 COG3512 COG3512, Uncharacterized protein conserved in bacteria Function unknown 60681298 Common nanH neuraminidase precursor BF1806 20 COG4409 NanH, Neuraminidase (sialidase) Carbohydrate transport and metabolism 60683381 Common - putative TonB-family outer membrane receptor protein BF3944 14 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 60681319 Common - hypothetical protein BF1827 5 None None None 60681009 Pathogen - hypothetical protein BF1507 1 None None None 60681609 Pathogen - hypothetical protein BF2128 1 None None None 60679623 Pathogen - hypothetical protein BF0026 1 None None None 60682348 Pathogen - hypothetical protein BF2878 1 None None None 60683524 Pathogen - hypothetical protein BF4100 1 None None None 60683003 Common - putative lipoprotein BF3545 8 None None None 60679727 Common - hypothetical protein BF0131 21 None None None 60680797 Common - putative thioredoxin BF1279 219 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 60682768 Common - putative AraC-family regulatory protein BF3300 91 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60683213 Common - putative exported thioredoxin BF3768 52 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 60680738 Pathogen - hypothetical protein BF1215 3 None None None 60682189 Common - hypothetical protein BF2716 33 COG2966 COG2966, Uncharacterized conserved protein Function unknown 60683466 Common - putative low molecular weight protein-tyrosine-phosphatase BF4032 130 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 60679845 Common ftsQ putative cell division protein BF0252 6 None None None 60681416 Pathogen - hypothetical protein BF1927 1 None None None 60680595 Common - putative ribosomal large subunit pseudouridine synthase BF1056 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 60680191 Common - putative endo-beta-galactosidase BF0629 24 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 60680361 Common - putative hexuronate transporter BF0809 74 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 60682817 Common - putative cell wall biosynthesis related protein BF3352 12 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 60680313 Common - putative glycosyl hydrolase BF0758 101 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 60681050 Pathogen upfY putative transcriptional regulator BF1549 2 COG0250 NusG, Transcription antiterminator Transcription 60682632 Common - hypothetical protein BF3163 38 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 60680680 Common eno phosphopyruvate hydratase BF1155 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 60682267 Common - putative glycosyltransferase BF2796 183 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 60679926 Common - hypothetical protein BF0337 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 60682702 Common - putative RNA polymerase sigma factor BF3233 109 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60683012 Common - putative lipoprotein BF3554 5 None None None 60682207 Common - putative RNA-binding protein BF2734 65 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 60683490 Common - putative TonB-linked outer membrane protein BF4062 29 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 60680198 Common - possible cytosine deaminase BF0637 211 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 60683624 Pathogen - hypothetical protein BF4204 1 None None None 60680321 Common - possible methyltransferase BF0767 4 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 60681503 Common - putative bacteriophage Gp25 protein BF2015 2 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 60681621 Common - putative outer membrane protein BF2142 102 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 60681489 Pathogen - hypothetical protein BF2001 1 None None None 60680761 Common - conserved hypothetical protein found on conjugate transposon BF1241 60 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 60683552 Common - putative anti-sigma factor BF4131 35 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 60681825 Pathogen - hypothetical protein BF2347 2 None None None 60680580 Common - hypothetical protein BF1038 61 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 60682800 Pathogen - putative AraC-family regulatory protein BF3333 8 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 60681736 Common - hypothetical protein BF2257 4 None None None 60682415 Common - putative puter membrane protein BF2945 126 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 60680083 Common - putative 5'nucleotidase/UDP-sugar hydrolase BF0514 93 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 60683019 Common - hypothetical protein BF3561 9 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 60682478 Pathogen - hypothetical protein BF3008 2 None None None 60681463 Pathogen - hypothetical protein BF1975 2 None None None 60680257 Common surE stationary phase survival protein SurE BF0698 185 COG0496 SurE, Predicted acid phosphatase General function prediction only 60681808 Pathogen - hypothetical protein BF2329A 1 None None None 60682184 Common - hypothetical protein BF2711 16 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 60679871 Common - putative beta-glucosidase BF0278 125 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 60680634 Common - putative ATP-dependent DNA helicase BF1103 228 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 60680508 Common - putative RNA polymerase ECF-type sigma factor BF0961 161 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 60683560 Common - putative endo-beta-galactosidase BF4139 46 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 60682870 Common maeB malic enzyme BF3408 216 COG0281 SfcA, Malic enzyme Energy production and conversion 60681466 Pathogen - hypothetical protein BF1978 1 None None None 60682091 Pathogen - putative lipoprotein BF2612 2 None None None 60682639 Common - putative exported glycine betaine-binding protein BF3170 68 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 60680944 Common - putative ABC transporter permease component BF1435 12 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 60683299 Common - putative exported esterase BF3857 19 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 60683438 Common rplC 50S ribosomal protein L3 BF4003 223 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 60683307 Common - conserved hypothetical fusion protein BF3865 2 None None None 60680759 Common - conserved hypothetical protein found on conjugate transposon BF1239 5 None None None 60681334 Common - putative phage integrase/recombinase BF1843 134 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 60682340 Pathogen - hypothetical protein BF2870 1 None None None 60682938 Common - hypothetical protein BF3478 37 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 60681724 Common - putative cobalamin synthesis related methyltransferase protein BF2245 111 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 60682303 Pathogen - hypothetical protein BF2832 1 None None None 60680979 Pathogen - hypothetical protein BF1477 1 None None None 60681090 Pathogen - hypothetical protein BF1594 1 None None None 60683691 Common - putative O-methyltransferase BF4276 103 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 60683585 Common - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase BF4164 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 60681070 Common - putative A/G-specific adenine glycosylase BF1569 219 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 60681517 Common - putative ATP-binding protein BF2029 32 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 60681602 Pathogen - hypothetical protein BF2121 1 None None None 60682022 Common - hypothetical protein BF2542 16 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 60681890 Pathogen - hypothetical protein BF2411 1 None None None 60682457 Common - putative ABC transport system, lipoprotein BF2987 162 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 60681708 Pathogen - hypothetical protein BF2229 2 None None None 60683632 Pathogen - hypothetical protein BF4212 1 None None None 60679878 Common - putative exported glutaminase BF0285 5 None None None 60681777 Common - hypothetical protein BF2299 3 None None None 60683331 Common clpP putative ATP-dependent CLP protease proteolytic subunit BF3894 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion