Yersinia pestis CO92 plasmid pCD1, complete sequence NC_003131 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 16082718 Common sycD secretion chaperone YPCD1.30c 19 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 16082753 Common ORFC putative transposase YPCD1.65 58 None None None 16082746 Pathogen lcrO type III secretion apparatus component YPCD1.58 5 None None None 16082732 Common yscR type III secretion system protein YPCD1.44 128 COG4790 EscR, Type III secretory pathway, component EscR Intracellular trafficking and secretion 16082712 Pathogen - hypothetical protein YPCD1.23 1 None None None 16082726 Pathogen tyeA Yop secretion and targeting control protein YPCD1.38c 5 None None None 16082737 Common virF transcriptional regulator YPCD1.49 114 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 40548798 Pathogen - hypothetical protein YPCD1.91n 1 None None None 16082703 Common sopA sopAB transcription repressor YPCD1.13c 198 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 16082698 Pathogen - hypothetical protein YPCD1.07 1 None None None 16082765 Pathogen tap repA translation protein YPCD1.78c 1 None None None 16082780 Common - putative transposase YPCD1.97c 84 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 16082734 Common yscT needle complex export protein YPCD1.46 22 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 16082749 Common yscL type III secretion system protein YPCD1.61 46 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 16082773 Common tnpA putative transposase YPCD1.90c 54 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 16082751 Common lcrS putative transposase YPCD1.63 54 None None None 16082710 Pathogen sycT YopT chaperone YPCD1.21 3 None None None 16082696 Pathogen yerA secretion chaperone YPCD1.05c 3 None None None 16082744 Pathogen yscG type III secretion apparatus component YPCD1.56 5 None None None 16082739 Pathogen yscB type III secretion apparatus component YPCD1.51 5 None None None 16082775 Pathogen - hypothetical protein YPCD1.92 1 None None None 16082705 Common - hypothetical protein YPCD1.15c 114 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 16082761 Pathogen - hypothetical protein YPCD1.73c 3 None None None 16082722 Common yscV low calcium response protein D YPCD1.34c 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 16082764 Common repA1 replication protein YPCD1.77c 8 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 16082729 Pathogen yscO type III secretion apparatus component YPCD1.41 5 None None None 16082774 Common tnpR putative resolvase YPCD1.91 146 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 16082750 Pathogen lcrQ LCR negative regulator YPCD1.62 2 None None None 16082747 Common ylpB needle complex inner membrane lipoprotein YPCD1.59 42 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 16082735 Common yscU needle complex export protein YPCD1.47 129 COG4792 EscU, Type III secretory pathway, component EscU Intracellular trafficking and secretion 16082742 Pathogen yscE type III secretion apparatus component YPCD1.54 1 None None None 16082716 Pathogen yopD secreted effector protein YPCD1.28c 5 None None None 16082693 Common - transposase/IS protein YPCD1.02 100 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 16082740 Common yscC outer membrane secretin precursor YPCD1.52 139 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 16082766 Pathogen copB replication protein YPCD1.79c 5 None None None 16082778 Pathogen sycH secretion chaperone YPCD1.95c 2 None None None 16082730 Pathogen yscP type III secretion apparatus component YPCD1.42 4 None None None 16082755 Pathogen yopH putative secreted protein-tyrosine phosphatase YPCD1.67c 4 COG5599 PTP2, Protein tyrosine phosphatase Signal transduction mechanisms 16082708 Pathogen yopQ Yop targeting protein YPCD1.19c 1 None None None 16082724 Pathogen yscX hypothetical protein YPCD1.36c 5 None None None 16082725 Pathogen sycN hypothetical protein YPCD1.37c 5 None None None 16082738 Pathogen yscA hypothetical protein YPCD1.50 1 None None None 40548797 Common - hypothetical protein YPCD1.14n 25 None None None 16082697 Pathogen yopE putative outer membrane virulence protein YPCD1.06 3 None None None 16082745 Pathogen yopR secreted protein YPCD1.57 4 None None None 16082717 Pathogen yopB secreted effector protein YPCD1.29c 5 COG5613 COG5613, Uncharacterized conserved protein Function unknown 16082743 Common yscF needle complex major subunit YPCD1.55 6 None None None 16082731 Common yscQ type III secretion system protein YPCD1.43 21 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 16082776 Common - putative transposase YPCD1.93 64 None None None 16082706 Common - hypothetical protein YPCD1.16c 64 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 16082720 Pathogen lcrG low calcium response protein G YPCD1.32c 5 None None None 16082727 Common lcrE secretion control protein YPCD1.39c 7 None None None 16082733 Common yscS needle complex export protein YPCD1.45 39 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 16082760 Common ypkA secreted protein kinase YPCD1.72c 5 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 16082719 Pathogen lcrV secreted effector protein YPCD1.31c 5 None None None 16082711 Pathogen - hypothetical protein YPCD1.22c 1 None None None 16082728 Common yscN type III secretion system ATPase YPCD1.40 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 16082715 Common yopM secreted effector protein YPCD1.26c 10 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 16082692 Common - putative transposase YPCD1.01 82 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 16082741 Common yscD virulence protein YPCD1.53 8 None None None 16082721 Pathogen lcrR low calcium response protein R YPCD1.33c 5 None None None 16082736 Pathogen virG needle complex outer membrane lipoprotein precursor YPCD1.48 4 None None None 40548796 Common - hypothetical protein YPCD1.09c 22 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 16082779 Common - putative transposase YPCD1.96c 89 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 16082702 Common sopB putative plasmid-partitioning control protein YPCD1.12c 22 COG1475 Spo0J, Predicted transcriptional regulators Transcription 16082759 Pathogen yopJ targeted effector protein YPCD1.71c 7 None None None 16082699 Common - hypothetical protein YPCD1.08c 24 COG3668 ParE, Plasmid stabilization system protein General function prediction only 16082748 Pathogen yscK type III secretion apparatus component YPCD1.60 5 None None None 16082709 Common yopT Yop targeted effector YPCD1.20 6 None None None 16082723 Pathogen yscY hypothetical protein YPCD1.35c 5 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 16082777 Common - putative transposase YPCD1.94 128 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair