Mycobacterium bovis AF2122/97, complete genome NC_002945 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 31793648 Common pepN PROBABLE AMINOPEPTIDASE N PEPN (LYSYL AMINOPEPTIDASE) (LYS-AP) (ALANINE AMINOPEPTIDASE) Mb2494 164 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 31793593 Common - hypothetical protein Mb2437c 32 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 31794432 Common alkB PROBABLE TRANSMEMBRANE ALKANE 1-MONOOXYGENASE ALKB (ALKANE 1-HYDROXYLASE) (LAURIC ACID OMEGA-HYDROXYLASE) (OMEGA-HYDROXYLASE) (FATTY ACID OMEGA-HYDROXYLASE) (ALKANE HYDROXYLASE-RUBREDOXIN) Mb3280c 27 COG3239 DesA, Fatty acid desaturase Lipid metabolism 31793933 Common - hypothetical protein Mb2780c 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 31793187 Common fdxA PROBABLE FERREDOXIN FDXA Mb2030c 128 COG1146 COG1146, Ferredoxin Energy production and conversion 31792117 Common pstA1 PROBABLE PHOSPHATE-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER PSTA1 Mb0953 222 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 31793005 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1846 16 COG1309 AcrR, Transcriptional regulator Transcription 31793332 Common murC UDP-N-acetylmuramate--L-alanine ligase Mb2176c 207 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 31792789 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase Mb1629 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 31793688 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE LEUCINE AND ALANINE RICH PROTEIN Mb2536c 61 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 31794244 Common mmr MULTIDRUGS-TRANSPORT INTEGRAL MEMBRANE PROTEIN MMR Mb3092 112 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 31792293 Common - hypothetical protein Mb1130 4 None None None 31791278 Pathogen - hypothetical protein Mb0103 1 None None None 31794736 Common fadE30 PROBABLE ACYL-COA DEHYDROGENASE FADE30 Mb3590c 150 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31792502 Common atpG F0F1 ATP synthase subunit gamma Mb1341 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 31794383 Common moeB1 molybdopterin biosynthesis-like protein MoeZ Mb3231c 230 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 31792520 Common - POSSIBLE THIOREDOXIN Mb1359 158 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 31794716 Common ltp2 lipid-transfer protein Mb3570c 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31794828 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3682c 1 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 31792251 Common - hypothetical protein Mb1089 1 None None None 31791416 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb0244 102 COG1309 AcrR, Transcriptional regulator Transcription 31793404 Common - Probable exported protease Mb2248c 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31792933 Common idi isopentenyl-diphosphate delta-isomerase Mb1774c 47 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 31793531 Pathogen esxO PUTATIVE ESAT-6 LIKE PROTEIN 6 Mb2375c 1 None None None 31791837 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb0672c 50 COG1309 AcrR, Transcriptional regulator Transcription 31791572 Pathogen - hypothetical protein Mb0402 1 None None None 31794439 Common - hypothetical protein Mb3287 15 None None None 31793434 Pathogen - Probable integral membrane protein Mb2278c 1 None None None 31792439 Common - hypothetical protein Mb1278c 11 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 31794563 Common idsB POSSIBLE POLYPRENYL SYNTHETASE IDSB (POLYPRENYL TRANSFERASE) (POLYPRENYL DIPHOSPHATE SYNTHASE) Mb3415c 239 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 31791925 Pathogen - hypothetical protein Mb0760 1 None None None 31792434 Common - hypothetical protein Mb1273 2 None None None 31793176 Common - hypothetical protein Mb2019 18 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 31794747 Common - POSSIBLE OXIDOREDUCTASE Mb3601c 76 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31793137 Common - hypothetical protein Mb1980 7 None None None 31794137 Common - PROBABLE TRANSPOSASE Mb2985 9 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 31791566 Common - hypothetical protein Mb0396 46 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 31794449 Common - hypothetical protein Mb3297 2 None None None 31792706 Common - probable sugar transferase Mb1547 133 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 31792740 Common - Possible regulatory protein Mb1581 29 COG1309 AcrR, Transcriptional regulator Transcription 31794650 Common kgtP PROBABLE DICARBOXYLIC ACID TRANSPORT INTEGRAL MEMBRANE PROTEIN KGTP (DICARBOXYLATE TRANSPORTER) Mb3503c 126 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31793699 Common lppS PROBABLE CONSERVED LIPOPROTEIN LPPS Mb2547c 19 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 31792813 Common - lipid-transfer protein Mb1653c 92 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31791553 Common - hypothetical protein Mb0383c 113 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 31793483 Common - hypothetical protein Mb2327 4 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 31794947 Common echA21 enoyl-CoA hydratase Mb3803 166 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31791220 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY) Mb0044c 99 COG1802 GntR, Transcriptional regulators Transcription 31792649 Common - hypothetical protein Mb1490 8 None None None 31793585 Common - hypothetical protein Mb2429c 75 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 31794465 Common accA3 PROBABLE BIFUNCTIONAL PROTEIN ACETYL-/PROPIONYL-COENZYME A CARBOXYLASE (ALPHA CHAIN) ACCA3: BIOTIN CARBOXYLASE + BIOTIN CARBOXYL CARRIER PROTEIN (BCCP) Mb3313 233 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 31792357 Common narJ PROBABLE RESPIRATORY NITRATE REDUCTASE (DELTA CHAIN) NARJ Mb1195 52 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 31794640 Common rmlB1 PROBABLE DTDP-GLUCOSE 4,6-DEHYDRATASE RMLB1 Mb3493 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 31792646 Pathogen PE_PGRS28 PE-PGRS FAMILY PROTEIN Mb1487c 1 None None None 31793010 Common ilvG hypothetical protein Mb1851 219 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 31794939 Common - hypothetical protein Mb3795 1 None None None 31792380 Common rocA PROBABLE PYRROLINE-5-CARBOXYLATE DEHYDROGENASE ROCA Mb1219 217 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 31794616 Common - CONSERVED HYPOTHETICAL ALANINE AND PROLINE RICH PROTEIN Mb3469c 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 31792807 Common cydD PROBABLE 'COMPONENT LINKED WITH THE ASSEMBLY OF CYTOCHROME' TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER CYDD Mb1647c 245 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 31793197 Common - hypothetical regulatory protein Mb2040 49 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 31791585 Common fgd1 PROBABLE F420-DEPENDENT GLUCOSE-6-PHOSPHATE DEHYDROGENASE FGD1 Mb0415 60 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31793643 Common tig trigger factor Mb2489c 211 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 31791814 Common echA3 enoyl-CoA hydratase Mb0649c 122 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31793681 Common accA1 PROBABLE ACETYL-/PROPIONYL-COENZYME A CARBOXYLASE ALPHA CHAIN (ALPHA SUBUNIT) ACCA1: BIOTIN CARBOXYLASE + BIOTIN CARBOXYL CARRIER PROTEIN (BCCP) Mb2529c 237 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 31794692 Common - hypothetical protein Mb3546 8 None None None 31792163 Common accD2 PROBABLE ACETYL-/PROPIONYL-COA CARBOXYLASE (BETA SUBUNIT) ACCD2 Mb0999c 151 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 31794646 Common ilvB2 PROBABLE ACETOLACTATE SYNTHASE (LARGE SUBUNIT) ILVB2 (AHAS) (ACETOHYDROXY-ACID SYNTHASE LARGE SUBUNIT) (ALS) Mb3499c 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 31791242 Common - hypothetical protein Mb0066 4 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31792885 Common pyrG CTP synthetase Mb1725 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 31794216 Common - hypothetical protein Mb3064c 83 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31791271 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb0096c 4 COG5660 COG5660, Predicted integral membrane protein Function unknown 31795028 Common ethA MONOOXYGENASE ETHA Mb3884c 62 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 31794372 Common - PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER Mb3220 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 31791633 Common - hypothetical protein Mb0463c 1 None None None 31794956 Common rfbD PROBABLE O-ANTIGEN/LIPOPOLYSACCHARIDE TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER RFBD Mb3812 101 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 31794277 Pathogen - hypothetical protein Mb3125c 1 None None None 31793996 Common - hypothetical protein Mb2844c 13 COG1567 COG1567, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 31792991 Pathogen PE_PGRS32b PE-PGRS FAMILY PROTEIN [SECOND PART] Mb1831c 1 None None None 31794665 Common - hypothetical protein Mb3519 3 None None None 31794324 Common nuoD NADH dehydrogenase subunit D Mb3172 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 31793965 Common fadE21 PROBABLE ACYL-CoA DEHYDROGENASE FADE21 Mb2812c 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31791246 Common sdaA PROBABLE L-SERINE DEHYDRATASE SDAA (L-SERINE DEAMINASE) (SDH) (L-SD) Mb0070c 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 31794257 Pathogen hab PROBABLE HYDROXYLAMINOBENZENE MUTASE HAB Mb3105 1 None None None 31791944 Common - hypothetical protein Mb0779c 2 None None None 31794270 Common - hypothetical protein Mb3118 3 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 31793165 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb2008 76 COG1279 COG1279, Lysine efflux permease General function prediction only 31794607 Common - POSSIBLE TRANSPOSASE Mb3460c 131 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 31795052 Common - CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN Mb3908 1 None None None 31793252 Common sigC RNA polymerase sigma factor SigC Mb2095 144 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 31794816 Common topA DNA topoisomerase I Mb3670c 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 31793858 Common - PROBABLE ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE LEUCINE AND ALANINE AND VALINE RICH PROTEIN ABC TRANSPORTER Mb2705c 9 None None None 31792534 Common murI glutamate racemase Mb1373 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 31794903 Common ligC ATP-dependent DNA ligase Mb3758 104 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 31791537 Common - hypothetical protein Mb0367c 14 None None None 31793209 Common - histidine kinase response regulator Mb2052c 36 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 31792176 Common - PROBABLE ADHESION COMPONENT TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER Mb1012 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 31793830 Pathogen - hypothetical protein Mb2677c 1 None None None 31791879 Common - hypothetical protein Mb0714 75 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 31791894 Common rpmC 50S ribosomal protein L29 Mb0729 149 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 31792971 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb1811 6 None None None 31793337 Common murF UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diamino pimelate-D-alanyl-D-alanyl ligase MurF Mb2181c 205 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 31792446 Common deaD PROBABLE COLD-SHOCK DEAD-BOX PROTEIN A HOMOLOG DEAD (ATP-dependent RNA helicase deaD homolog) Mb1285 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 31793054 Common - hypothetical protein Mb1895c 78 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 31793625 Common rne POSSIBLE RIBONUCLEASE E RNE Mb2471c 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 31793971 Common - hypothetical protein Mb2818c 11 COG1409 Icc, Predicted phosphohydrolases General function prediction only 31792890 Common cycA PROBABLE D-SERINE/ALANINE/GLYCINE TRANSPORTER PROTEIN CYCA Mb1730c 139 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 31793130 Common ephB PROBABLE EPOXIDE HYDROLASE EPHB (EPOXIDE HYDRATASE) Mb1973 140 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31792688 Common mutA PROBABLE METHYLMALONYL-COA MUTASE SMALL SUBUNIT MUTA (MCM) Mb1529 107 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 31793535 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ARSR-FAMILY) Mb2379 156 COG0640 ArsR, Predicted transcriptional regulators Transcription 31793692 Common - IS1081 transposase Mb2540c 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 31791597 Common lpqM POSSIBLE LIPOPROTEIN PEPTIDASE LPQM Mb0427 5 COG2321 COG2321, Predicted metalloprotease General function prediction only 31791315 Common msrA methionine sulfoxide reductase A Mb0142c 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 31794474 Common - hypothetical protein Mb3322c 37 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 31794867 Common glpKa PROBABLE GLYCEROL KINASE GLPKA [FIRST PART] (ATP:GLYCEROL 3-PHOSPHOTRANSFERASE)(GLYCEROKINASE) (GK) Mb3722c 172 COG0554 GlpK, Glycerol kinase Energy production and conversion 31794807 Common - PUTATIVE TRANSPOSASE Mb3661 25 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 31793880 Common - hypothetical protein Mb2727c 17 None None None 31791786 Common lpqO PROBABLE CONSERVED LIPOPROTEIN LPQO Mb0620 15 None None None 31791371 Pathogen - hypothetical protein Mb0199c 1 None None None 31793239 Common rpsN 30S ribosomal protein S14 Mb2082c 198 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 31793329 Common yfiH conserved hypothetical protein yfiH Mb2173c 161 COG1496 COG1496, Uncharacterized conserved protein Function unknown 31792967 Common - hypothetical protein Mb1807c 2 None None None 31793881 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2728 7 None None None 31791322 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY) Mb0149 102 COG1309 AcrR, Transcriptional regulator Transcription 31794568 Pathogen PE_PGRS52 PE-PGRS FAMILY PROTEIN Mb3420 1 None None None 31794178 Common ilvC ketol-acid reductoisomerase Mb3026c 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 31792421 Pathogen lpqX PUTATIVE LIPOPROTEIN LPQX Mb1260 1 None None None 31794580 Common - hypothetical protein Mb3432 32 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31794972 Common - PUTATIVE TRANSPOSASE [SECOND PART] Mb3828 38 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 31794426 Common mtrA TWO COMPONENT SENSORY TRANSDUCTION TRANSCRIPTIONAL REGULATORY PROTEIN MTRA Mb3274c 212 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31791683 Common galE2 POSSIBLE UDP-GLUCOSE 4-EPIMERASE GALE2 (GALACTOWALDENASE) (UDP-GALACTOSE 4-EPIMERASE) (URIDINE DIPHOSPHATE GALACTOSE 4-EPIMERASE) (URIDINE DIPHOSPHO-GALACTOSE 4-EPIMERASE) Mb0513 134 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 31793835 Pathogen - hypothetical protein Mb2682 1 None None None 31791515 Common aspC aminotransferase AlaT Mb0344c 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 31791252 Common - PROBABLE AMINOTRANSFERASE Mb0077 225 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 31791548 Common - hypothetical protein Mb0378c 60 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 31793217 Common - Probable ArsR-type repressor protein Mb2060 75 COG0640 ArsR, Predicted transcriptional regulators Transcription 31794877 Pathogen - CONSERVED HYPOTHETICAL PROLINE RICH PROTEIN Mb3732c 1 None None None 31793721 Common aroK shikimate kinase Mb2568c 200 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 31794788 Pathogen - hypothetical protein Mb3642c 1 None None None 31792460 Common - hypothetical protein Mb1299c 3 None None None 31794377 Common - POSSIBLE TRANSMEMBRANE CATION TRANSPORTER Mb3225c 144 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 31792664 Common trxA PROBABLE THIOREDOXIN TRXA Mb1505 194 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 31793288 Common PPE36 conserved hypothetical protein, PPE Mb2132 2 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794537 Common - hypothetical protein Mb3389 1 None None None 31791474 Common - hypothetical protein Mb0303c 10 COG4424 COG4424, Uncharacterized protein conserved in bacteria Function unknown 31792193 Common - hypothetical protein Mb1029c 32 COG1928 PMT1, Dolichyl-phosphate-mannose--protein O-mannosyl transferase Posttranslational modification, protein turnover, chaperones 31794778 Common panC pantoate--beta-alanine ligase Mb3632c 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 31793671 Common - hypothetical protein Mb2519 47 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 31793112 Common - PROBABLE MEMBRANE PROTEIN Mb1955 27 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 31792753 Pathogen - hypothetical membrane protein Mb1594c 1 None None None 31791186 Common ppiA PROBABLE IRON-REGULATED PEPTIDYL-PROLYL CIS-TRANS ISOMERASE A PPIA (PPIase A) (ROTAMASE A) Mb0009 179 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 31793343 Common pbpB Probable penicillin-binding membrane protein pbpB Mb2187c 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 31792569 Common - hypothetical protein Mb1410 31 COG1944 COG1944, Uncharacterized conserved protein Function unknown 31792589 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1430 80 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 31791568 Common ndhA PROBABLE MEMBRANE NADH DEHYDROGENASE NDHA Mb0398c 170 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 31794373 Common whiB7 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB7 Mb3221c 11 None None None 31791341 Common - hypothetical protein Mb0168 55 COG0824 FcbC, Predicted thioesterase General function prediction only 31791465 Common PPE4 PPE FAMILY PROTEIN Mb0294 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792618 Pathogen - POSSIBLE MEMBRANE PROTEIN Mb1459c 1 None None None 31793293 Common - Probable integral membrane protein Mb2137 3 None None None 31794888 Common - hypothetical protein Mb3743c 8 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 31792328 Pathogen - hypothetical protein Mb1165 1 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 31794530 Common PPE55a PPE FAMILY PROTEIN [FIRST PART] Mb3380c 5 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794204 Common - hypothetical protein Mb3052c 69 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 31793728 Pathogen - hypothetical protein Mb2575 1 COG5450 COG5450, Transcription regulator of the Arc/MetJ class Transcription 31794545 Common - PROBABLE ATP/GTP-BINDING PROTEIN Mb3397c 32 COG2229 COG2229, Predicted GTPase General function prediction only 31793492 Pathogen - hypothetical protein Mb2336 1 None None None 161511523 Common rnpA ribonuclease P Mb3954c 10 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 31791915 Common xylB POSSIBLE D-XYLULOSE KINASE XYLB (XYLULOKINASE) (XYLULOSE KINASE) Mb0750 99 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 31794774 Common lsr2 PROBABLE LSR2 PROTEIN PRECURSOR Mb3628c 17 None None None 31792918 Common - POSSIBLE PENICILLIN-BINDING PROTEIN Mb1759c 147 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 31792921 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb1762c 3 None None None 31794233 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb3081 7 COG1309 AcrR, Transcriptional regulator Transcription 31793423 Common fabD acyl-carrier-protein S-malonyltransferase Mb2267 198 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 31793281 Pathogen PE_PGRS36 conserved hypothetical protein, PE_PGRS family Mb2125c 1 None None None 31792976 Pathogen PE18 PE FAMILY PROTEIN Mb1816 1 None None None 31792763 Common - Probable phiRv1 phage protein Mb1603c 9 COG3740 COG3740, Phage head maturation protease General function prediction only 31793472 Common - Probable aminotransferase Mb2316 214 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 31792323 Common - PROBABLE TRANSCRIPTIONAL REGULATOR PROTEIN Mb1160c 50 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 31791655 Common hbhA HEPARIN BINDING HEMAGGLUTININ HBHA (ADHESIN) Mb0485 4 COG1754 COG1754, Uncharacterized C-terminal domain of topoisomerase IA General function prediction only 31793031 Common - hypothetical protein Mb1872c 211 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 31791211 Pathogen - hypothetical protein Mb0035 1 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 31791604 Pathogen - POSSIBLE TRANSMEMBRANE PROTEIN Mb0434c 1 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 31791912 Common - hypothetical protein Mb0747c 28 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31793240 Common rpmG 50S ribosomal protein L33 Mb2083c 130 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 31794990 Common - PUTATIVE ACYLTRANSFERASE Mb3846c 138 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 31794571 Common acrA1 short chain dehydrogenase Mb3423 221 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 31791502 Common - hypothetical protein Mb0331c 28 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 31794721 Common cyp125 PROBABLE CYTOCHROME P450 125 CYP125 Mb3575c 69 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31792734 Common PPE21 PPE FAMILY PROTEIN Mb1575c 14 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792998 Common PPE33a PPE FAMILY PROTEIN [FIRST PART] Mb1838 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792831 Common tsnR Possible 23S rRNA methyltransferase tsnR Mb1671 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 31791796 Common - hypothetical protein Mb0630c 10 None None None 31792952 Pathogen - hypothetical protein Mb1793c 1 COG0393 COG0393, Uncharacterized conserved protein Function unknown 161511528 Common moaC molybdenum cofactor biosynthesis protein C Mb3353c 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 31794576 Common - PROBABLE MEMBRANE PROTEIN Mb3428 2 None None None 31791256 Pathogen - hypothetical protein Mb0081c 1 None None None 31794042 Common - hypothetical protein Mb2890 11 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 31793418 Common ahpE peroxiredoxin AhpE Mb2262c 204 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 31794701 Common - POSSIBLE SIDEROPHORE-BINDING PROTEIN Mb3555c 191 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 31792722 Common ileS isoleucyl-tRNA synthetase Mb1563 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31791883 Pathogen - CONSERVED HYPOTHETICAL PROTEIN [SECOND PART] Mb0718 1 None None None 31794657 Common - PROBABLE INTEGRAL MEMBRANE PROTEIN Mb3511c 3 None None None 31792926 Common - hypothetical protein Mb1767 6 None None None 31793818 Common - hypothetical protein Mb2665c 6 None None None 31792666 Common echA12 enoyl-CoA hydratase Mb1507 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31794357 Common - hypothetical protein Mb3205 49 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 31794915 Common - hypothetical protein Mb3771c 42 COG3651 COG3651, Uncharacterized protein conserved in bacteria Function unknown 31794624 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb3477c 194 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 31793260 Pathogen - hypothetical protein Mb2103c 1 None None None 31791361 Common - POSSIBLE LYSOPHOSPHOLIPASE Mb0189 114 COG2267 PldB, Lysophospholipase Lipid metabolism 31794369 Common - hypothetical protein Mb3217 25 COG5282 COG5282, Uncharacterized conserved protein Function unknown 31794062 Common - PROBABLE RESOLVASE Mb2910c 13 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 31794687 Pathogen PE_PGRS55 PE-PGRS FAMILY PROTEIN Mb3541 1 None None None 31792013 Common - hypothetical protein Mb0848c 8 COG1309 AcrR, Transcriptional regulator Transcription 31794963 Common - PUTATIVE OXIDOREDUCTASE Mb3819 113 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 161511532 Common mraW S-adenosyl-methyltransferase MraW Mb2189c 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 31792031 Common - PROBABLE DEHYDROGENASE Mb0866 143 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 31793022 Common gcvB glycine dehydrogenase Mb1863 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 31794352 Common - amidase Mb3200 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 31793737 Common - Holliday junction resolvase-like protein Mb2584c 126 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 31794930 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb3786 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 31791724 Common menE O-succinylbenzoic acid--CoA ligase Mb0556c 210 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793544 Common - hypothetical protein Mb2388c 157 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 31792747 Common treZ Maltooligosyltrehalose trehalohydrolase TreZ Mb1588c 148 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 31793502 Common - hypothetical protein Mb2346c 9 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 31794636 Common rpsM 30S ribosomal protein S13 Mb3489c 244 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 31791938 Common mmsB PROBABLE 3-HYDROXYISOBUTYRATE DEHYDROGENASE MMSB (HIBADH) Mb0773c 175 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 31792074 Common fprB PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRB (ADRENODOXIN REDUCTASE) (AR) (FERREDOXIN-NADP(+) REDUCTASE) Mb0910 134 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 31792033 Common - POSSIBLE TWO COMPONENT SENSOR KINASE Mb0868 96 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 31794084 Common - hypothetical protein Mb2932c 53 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 31794754 Common - hypothetical protein Mb3608 5 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 31794069 Common - POSSIBLE OXIDOREDUCTASE Mb2917 38 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31794182 Common - hypothetical protein Mb3030c 56 COG2259 COG2259, Predicted membrane protein Function unknown 31792749 Common treYa Maltooligosyltrehalose synthase TreYa [FIRST PART] Mb1590c 71 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 31795064 Pathogen esxD hypothetical protein Mb3920c 1 None None None 31795092 Common gidB glucose-inhibited division protein B Mb3950c 199 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 31792735 Common fadD11 POSSIBLE FATTY-ACID-COA LIGASE FADD11 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-COA SYNTHASE) Mb1576 212 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 31794130 Common - hypothetical protein Mb2978c 2 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 31791284 Common - hypothetical protein Mb0109 59 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 31791734 Common - hypothetical protein Mb0567 107 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 31792871 Common - hypothetical protein Mb1711c 17 COG1309 AcrR, Transcriptional regulator Transcription 31792202 Common ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase Mb1038 185 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 31791644 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0474c 52 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 31792637 Common - hypothetical protein Mb1478c 6 COG4276 COG4276, Uncharacterized conserved protein Function unknown 31794157 Common ddl D-alanyl-alanine synthetase A Mb3005c 211 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 31793908 Common recX recombination regulator RecX Mb2755c 18 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 31791878 Common lldD1 POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD1 Mb0713 121 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 31795000 Common fadD23 acyl-CoA synthetase Mb3856 198 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31794848 Common - hypothetical protein Mb3702c 94 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 31792630 Common gap glyceraldehyde-3-phosphate dehydrogenase Mb1471 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 31793602 Common - hypothetical protein Mb2446 3 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 31791383 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0211 17 COG0628 PerM, Predicted permease General function prediction only 31791960 Common purD phosphoribosylamine--glycine ligase Mb0795 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 31791864 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0699c 1 None None None 31794280 Common ftsX PUTATIVE CELL DIVISION PROTEIN FTSX (SEPTATION COMPONENT-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER) Mb3128c 91 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 31792082 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY LUXR-FAMILY) Mb0918 28 COG3903 COG3903, Predicted ATPase General function prediction only 31793093 Common lipJ PROBABLE LIGNIN PEROXIDASE LIPJ Mb1935c 72 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31793283 Common helZ PROBABLE HELICASE HELZ Mb2127 118 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 31792359 Common typA POSSIBLE GTP-BINDING TRANSLATION ELONGATION FACTOR TYPA (TYROSINE PHOSPHORYLATED PROTEIN A) (GTP-BINDING PROTEIN) Mb1197 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 31793148 Pathogen - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1991 2 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 31793783 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb2630 1 None None None 31793079 Common - POSSIBLE TRANSMEMBRANE PROTEIN Mb1920c 7 None None None 31794149 Common - POSSIBLE CONSERVED MEMBRANE OR EXPORTED PROTEIN Mb2997c 24 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 31791496 Common glpQ2 PUTATIVE GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLPQ2 (GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE) Mb0325c 122 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 31792107 Common - hypothetical protein Mb0943 46 COG3153 COG3153, Predicted acetyltransferase General function prediction only 31791630 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0460 10 COG1309 AcrR, Transcriptional regulator Transcription 31793271 Common pknJ PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE J PKNJ (PROTEIN KINASE J) (STPK J) Mb2115 146 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 31794344 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb3192c 31 COG1309 AcrR, Transcriptional regulator Transcription 31792559 Common - POSSIBLE MEMBRANE PROTEIN Mb1398c 6 None None None 31793523 Common mmpL9a PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL9A [FIRST PART] Mb2367 52 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31792459 Common embR PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN EMBR Mb1298c 38 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 31792350 Common - CONSERVED HYPOTHETICAL ALA-, PRO-RICH PROTEIN Mb1188c 4 COG5373 COG5373, Predicted membrane protein Function unknown 31791826 Common mmaA4 METHOXY MYCOLIC ACID SYNTHASE 4 MMAA4 (METHYL MYCOLIC ACID SYNTHASE 4) (MMA4) (HYDROXY MYCOLIC ACID SYNTHASE) Mb0661c 125 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 31792277 Common - SHORT (C15) CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHASE (Z-FPP SYNTHASE) (Z-FARNESYL DIPHOSPHATE SYNTHASE) (Z-FPP SYNTHETASE) (Z-FARNESYL DIPHOSPHATE SYNTHETASE) (GERANYLTRANSTRANSFERASE) (FARNESYL PYROPHOSPHATE SYNTHETASE) Mb1115 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 31794794 Common hpt hypoxanthine-guanine phosphoribosyltransferase Mb3648c 139 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 31792216 Common - hypothetical protein Mb1053 26 COG1507 COG1507, Uncharacterized conserved protein Function unknown 31795019 Common - hypothetical protein Mb3875 4 None None None 161511525 Common truA tRNA pseudouridine synthase A Mb3484c 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 31792410 Common - PROBABLE TETRONASIN-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER Mb1249c 19 COG3559 TnrB3, Putative exporter of polyketide antibiotics Cell envelope biogenesis, outer membrane 31792786 Common hisC1 histidinol-phosphate aminotransferase Mb1626 232 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 31792609 Common ribA2 bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein Mb1450 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 31791983 Common - PROBABLE OXIDOREDUCTASE [SECOND PART] Mb0818c 170 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 31795043 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb3899 7 None None None 31794318 Common - hypothetical protein Mb3166c 1 None None None 31793109 Common PPE34 PPE FAMILY PROTEIN Mb1951c 31 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791394 Common - hypothetical protein Mb0222 21 COG2030 MaoC, Acyl dehydratase Lipid metabolism 31792855 Pathogen - hypothetical protein Mb1696 1 None None None 31791343 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY) Mb0170c 122 COG1802 GntR, Transcriptional regulators Transcription 31791748 Common - nucleotide-binding protein Mb0581c 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 31794162 Common hupB PROBABLE DNA-BINDING PROTEIN HU HOMOLOG HUPB (HISTONE-LIKE PROTEIN) (HLP) (21-KDA LAMININ-2-BINDING PROTEIN) Mb3010c 189 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 31793444 Common - Possible conserved integral membrane protein Mb2288 63 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 31791621 Common - hypothetical protein Mb0451 13 None None None 31793308 Pathogen - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2152 1 None None None 31791408 Common fadE4 PROBABLE ACYL-COA DEHYDROGENASE FADE4 Mb0236 103 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31793504 Common rocD2 PROBABLE ORNITHINE AMINOTRANSFERASE (C-terminus part) ROCD2 (ORNITHINE--OXO-ACID AMINOTRANSFERASE) Mb2348c 234 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 31791740 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase Mb0573 214 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31793040 Common ureC urease subunit alpha Mb1881 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 31794135 Common - POSSIBLE METHYLTRANSFERASE (METHYLASE) Mb2983c 24 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 31794879 Common - hypothetical protein Mb3734c 5 None None None 31792655 Common - hypothetical protein Mb1496 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 31792427 Common - PROBABLE TRANSMEMBRANE PROTEIN Mb1266 18 None None None 31792821 Common - hypothetical protein Mb1661c 8 COG5305 COG5305, Predicted membrane protein Function unknown 31791528 Common dnaK molecular chaperone DnaK Mb0358 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 31794880 Common asd aspartate-semialdehyde dehydrogenase Mb3735c 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 31794834 Common dppC PROBABLE DIPEPTIDE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DPPC Mb3688c 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 31793815 Common - hypothetical protein Mb2662 8 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 31792621 Common fadD12 acyl-CoA synthetase Mb1462c 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793072 Common lppE POSSIBLE CONSERVED LIPOPROTEIN LPPE Mb1913c 1 None None None 31794891 Common - hypothetical protein Mb3746 24 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 31793903 Common - CONSERVED HYPOTHETICAL ALANINE AND ARGININE RICH PROTEIN Mb2750 29 COG4717 COG4717, Uncharacterized conserved protein Function unknown 31791933 Pathogen PE_PGRS10 PE-PGRS FAMILY PROTEIN Mb0768 1 None None None 31791231 Common ssb single-strand DNA-binding protein Mb0055 200 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 31792452 Common - PROBABLE OXIDOREDUCTASE [SECOND PART] Mb1291 20 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 31794547 Common - hypothetical protein Mb3399c 10 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 31794111 Common ppsD PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSD Mb2959 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794306 Common - hypothetical protein Mb3154c 28 None None None 31795016 Common glpQ1 PROBABLE GLYCEROPHOSPHORYL DIESTER PHOSPHODIESTERASE GLPQ1 (GLYCEROPHOSPHODIESTER PHOSPHODIESTERASE) Mb3872c 166 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 31792222 Common kdpB potassium-transporting ATPase subunit B Mb1059 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 31793739 Common - hypothetical protein Mb2586c 93 COG0432 COG0432, Uncharacterized conserved protein Function unknown 31792676 Common - PROBABLE MEMBRANE PROTEIN Mb1517 54 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 31792137 Common - hypothetical protein Mb0973c 10 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 31791358 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0186c 8 COG1511 COG1511, Predicted membrane protein Function unknown 31793551 Common hrcA heat-inducible transcription repressor Mb2395c 150 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 31792348 Common - hypothetical protein Mb1186 11 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 31791763 Pathogen - hypothetical protein Mb0596 1 None None None 31793715 Common nusB transcription antitermination protein NusB Mb2562c 96 COG0781 NusB, Transcription termination factor Transcription 31792907 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1748 115 COG1414 IclR, Transcriptional regulator Transcription 31794766 Common mutY PUTATIVE ADENINE GLYCOSYLASE Mb3620 190 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 31792211 Common mfd PROBABLE TRANSCRIPTION-REPAIR COUPLING FACTOR MFD (TRCF) Mb1048 227 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 31794870 Common - hypothetical protein Mb3725 14 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 31792574 Common pyrB aspartate carbamoyltransferase catalytic subunit Mb1415 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 31794349 Pathogen - hypothetical protein Mb3197c 2 None None None 31793917 Common - POSSIBLE CONSERVED MEMBRANE ALANINE RICH PROTEIN Mb2764c 4 None None None 31794837 Common acs acetyl-CoA synthetase Mb3691 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 31792691 Pathogen - hypothetical protein Mb1532 1 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 31794900 Common - PROBABLE CONSERVED TWO-DOMAIN MEMBRANE PROTEIN Mb3755 211 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 31791769 Common yrbE2A CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE2A Mb0602 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 31795087 Common trxC THIOREDOXIN TRXC (TRX) (MPT46) Mb3945 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 31791401 Common - POSSIBLE METHYLTRANSFERASE (METHYLASE) Mb0229c 41 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31792714 Common papA4 PROBABLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA4 Mb1555c 1 None None None 31793730 Pathogen - hypothetical protein Mb2577 1 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 31793129 Common - POSSIBLE OXYGENASE Mb1972 148 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 31792416 Common htrA PROBABLE SERINE PROTEASE HTRA (DEGP PROTEIN) Mb1255 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 31791678 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0508 4 None None None 31794852 Common whiB4 PUTATIVE TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB4 Mb3706c 19 None None None 31791807 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0641c 4 COG0398 COG0398, Uncharacterized conserved protein Function unknown 31791846 Pathogen - hypothetical protein Mb0681c 1 None None None 31791428 Common - hypothetical protein Mb0256c 5 None None None 31792291 Common fumC fumarate hydratase Mb1128c 235 COG0114 FumC, Fumarase Energy production and conversion 31792341 Common - hypothetical protein Mb1178 11 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 31793355 Common - POSSIBLE TRANSPOSASE Mb2199c 69 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 31792988 Common PPE28 PPE FAMILY PROTEIN Mb1828 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793254 Common cobM Probable precorrin-4 C11-methyltransferase CobM Mb2097c 200 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 31791975 Common - hypothetical protein Mb0810 1 None None None 31791397 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0225 4 None None None 31793124 Common tpx thiol peroxidase Mb1967 117 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 31791995 Common - hypothetical protein Mb0830 18 None None None 31793824 Common - hypothetical protein Mb2671 3 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 31791521 Common iniC ISONIAZID INDUCTIBLE GENE PROTEIN INIC Mb0350 24 COG0699 COG0699, Predicted GTPases (dynamin-related) General function prediction only 31794108 Common ppsA PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSA Mb2956 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794364 Common - hypothetical protein Mb3212c 8 None None None 31792540 Common - acyl carrier protein Mb1379 3 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792042 Common - hypothetical protein Mb0877 8 None None None 31793474 Common - haloalkane dehalogenase Mb2318 119 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31791702 Common - POSSIBLE METHYLTRANSFERASE/METHYLASE (FRAGMENT) Mb0533 55 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31793958 Common pepR PROBABLE ZINC PROTEASE PEPR Mb2805c 178 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 31795046 Common PE35 PE FAMILY-LIKE PROTEIN Mb3902 1 None None None 31792273 Common mca Mycothiol conjugate amidase Mca (Mycothiol S-conjugate amidase) Mb1111 40 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 31794191 Common ligA NAD-dependent DNA ligase LigA Mb3039c 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 31793312 Pathogen - hypothetical protein Mb2156 1 None None None 31792243 Pathogen - hypothetical protein Mb1081 1 None None None 31794603 Common - hypothetical protein Mb3456c 143 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 31794585 Common - hypothetical protein Mb3438c 78 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 31792314 Common - hypothetical protein Mb1151c 11 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31794814 Common - DNA polymerase III subunit delta' Mb3668c 216 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 31793399 Common - PROBABLE MEMBRANE PROTEIN Mb2243c 8 None None None 31794800 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb3654 3 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 31792552 Common - hypothetical protein Mb1391c 3 None None None 31793061 Common - hypothetical protein Mb1902c 3 None None None 31795050 Common - CONSERVED HYPOTHETICAL PROLINE AND ALANINE RICH PROTEIN Mb3906 13 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 31793922 Common ftsK POSSIBLE CELL DIVISION TRANSMEMBRANE PROTEIN FTSK Mb2769c 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 31792389 Common PPE18 PPE FAMILY PROTEIN Mb1228 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791802 Common galK galactokinase Mb0636 75 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 31793632 Pathogen - HYPOTHETICAL PROLINE AND SERINE RICH PROTEIN Mb2478 1 None None None 31794506 Common moaB3 PROBABLE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE MOAB3 (PHS) (4-ALPHA-HYDROXY-TETRAHYDROPTERIN DEHYDRATASE) (PTERIN-4-A-CARBINOLAMINE DEHYDRATASE) (PHENYLALANINE HYDROXYLASE-STIMULATING PROTEIN) (PHS) (PTERIN CARBINOLAMINE DEHYDRATASE) (PCD) Mb3354c 66 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 31794092 Common ffh PROBABLE SIGNAL RECOGNITION PARTICLE PROTEIN FFH (FIFTY-FOUR HOMOLOG) Mb2940c 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 31791448 Common fadD2 acyl-CoA synthetase Mb0276 220 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793164 Common - chromosome replication initiation inhibitor protein Mb2007c 109 COG0583 LysR, Transcriptional regulator Transcription 31793946 Common - hypothetical protein Mb2793c 27 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 31794498 Common sdhD PROBABLE SUCCINATE DEHYDROGENASE (HYDROPHOBIC MEMBRANE ANCHOR SUBUNIT) SDHD (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE) Mb3346 13 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 31792378 Common fadD21 acyl-CoA synthetase Mb1217c 205 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792178 Common - PROBABLE ADHESION COMPONENT TRANSPORT TRANSMEMBRANE PROTEIN ABC TRANSPORTER Mb1014 62 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 31791304 Common pepA PROBABLE SERINE PROTEASE PEPA Mb0130 218 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 31791570 Pathogen - POSSIBLE SECRETED PROTEIN Mb0400c 1 None None None 31792591 Common - hypothetical protein Mb1432c 6 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31795074 Pathogen - POSSIBLE MEMBRANE PROTEIN Mb3931c 1 None None None 31791606 Common - hypothetical protein Mb0436c 11 None None None 31792067 Pathogen - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb0903c 1 None None None 31793089 Common - hypothetical protein Mb1931c 27 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31791419 Common - hypothetical protein Mb0247c 32 COG2030 MaoC, Acyl dehydratase Lipid metabolism 31792333 Common - PUTATIVE OXIDOREDUCTASE Mb1170c 10 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 31793513 Common lppP PROBABLE LIPOPROTEIN LPPP Mb2357c 2 None None None 31793605 Common - hypothetical protein Mb2449c 43 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 31792029 Pathogen - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0864 1 None None None 31792298 Common - POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) Mb1135 28 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 31794296 Common cysA3 PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA3 (RHODANESE-LIKE PROTEIN) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE) Mb3144 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 31794339 Pathogen - POSSIBLE INTEGRAL MEMBRANE PROTEIN Mb3187c 1 None None None 31794612 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3465c 2 None None None 31795071 Pathogen - hypothetical protein Mb3927c 1 None None None 31794759 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Mb3613c 193 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 31792584 Common rpoZ DNA-directed RNA polymerase subunit omega Mb1425 22 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 31794526 Common - POSSIBLE METHYLTRANSFERASE (METHYLASE) Mb3374 155 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31793862 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE AND VALINE AND LEUCINE RICH PROTEIN Mb2709c 43 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 31791302 Pathogen - hypothetical protein Mb0128 1 None None None 31792981 Pathogen esxN PUTATIVE ESAT-6 LIKE PROTEIN 5 Mb1821 1 None None None 31794996 Common - hypothetical protein Mb3852 1 None None None 31794129 Common - hypothetical protein Mb2977 48 COG3268 COG3268, Uncharacterized conserved protein Function unknown 31791333 Common pntAa PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT ALPHA) PNTAa [FIRST PART; CATALYTIC PART] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA) (NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA) Mb0160 152 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 31792564 Common lprF PUTATIVE LIPOPROTEIN LPRF Mb1403 3 None None None 31792306 Common - hypothetical protein Mb1143 12 None None None 31792376 Common mmpL10 PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL10 Mb1215 75 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31791331 Common ptbB PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPB (PROTEIN-TYROSINE-PHOSPHATASE) (PTPase) Mb0158c 49 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 31792095 Common - hypothetical protein Mb0931 89 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 31793577 Common cysT PROBABLE SULFATE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER CYST Mb2421c 235 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 31794289 Common moaB1 PROBABLE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE MOAB1 (PHS) (4-ALPHA-HYDROXY-TETRAHYDROPTERIN DEHYDRATASE) (PTERIN-4-A-CARBINOLAMINE DEHYDRATASE) (PHENYLALANINE HYDROXYLASE-STIMULATING PROTEIN) (PHS) (PTERIN CARBINOLAMINE DEHYDRATASE) (PCD) Mb3137 78 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 31791610 Common sodC PROBABLE PERIPLASMIC SUPEROXIDE DISMUTASE [CU-ZN] SODC Mb0440 75 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 31793753 Common - hypothetical protein Mb2600 7 COG3801 COG3801, Uncharacterized protein conserved in bacteria Function unknown 31794001 Common - hypothetical protein Mb2849c 9 COG4293 COG4293, Uncharacterized protein conserved in bacteria Function unknown 31794428 Common sahH S-adenosyl-L-homocysteine hydrolase Mb3276c 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 31793558 Common mbtD POLYKETIDE SYNTHETASE MBTD (POLYKETIDE SYNTHASE) Mb2402c 86 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31791691 Common hemA glutamyl-tRNA reductase Mb0521 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 31791899 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0734 3 None None None 31792403 Common tagA PROBABLE DNA-3-METHYLADENINE GLYCOSYLASE I TAGA (TAG I) (3-methyladenine-DNA glycosylase I, constitutive) (DNA-3-methyladenine glycosidase I ) Mb1242 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 31791898 Common - hypothetical protein Mb0733 102 COG1262 COG1262, Uncharacterized conserved protein Function unknown 31794925 Common - hypothetical protein Mb3781c 13 COG3554 COG3554, Uncharacterized protein conserved in bacteria Function unknown 31794269 Pathogen - HYPOTHETICAL ALANINE AND VALINE RICH PROTEIN Mb3117 1 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 31794840 Common ephE POSSIBLE EPOXIDE HYDROLASE EPHE (EPOXIDE HYDRATASE) (ARENE-OXIDE HYDRATASE) Mb3694 121 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31794714 Common - PROBABLE DEHYDROGENASE Mb3568 28 COG2030 MaoC, Acyl dehydratase Lipid metabolism 31793244 Common - hypothetical protein Mb2087c 12 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 31794235 Common - short chain dehydrogenase Mb3083c 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 31793570 Common - hypothetical protein Mb2414 53 COG2138 COG2138, Uncharacterized conserved protein Function unknown 31794706 Common - short chain dehydrogenase Mb3560c 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31791968 Common hemH phosphoribosylaminoimidazole-succinocarboxamide synthase Mb0803 175 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 31793047 Common modA PROBABLE MOLYBDATE-BINDING LIPOPROTEIN MODA Mb1888 138 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 31791712 Common - hypothetical protein Mb0543 30 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 31794952 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN ALANINE AND LEUCINE RICH Mb3808 3 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 31791781 Common - hypothetical protein Mb0615c 2 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 31792604 Common - AMINOGLYCOSIDES/TETRACYCLINE-TRANSPORT INTEGRAL MEMBRANE PROTEIN Mb1445c 209 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31791193 Common pbpA PROBABLE PENICILLIN-BINDING PROTEIN PBPA Mb0016c 203 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 31795021 Common - hypothetical protein Mb3877 3 None None None 31794413 Common pvdS POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN PVDS (PROBABLE RNA POLYMERASE SIGMA FACTOR) Mb3261c 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 31791788 Common - PUTATIVE TRANSPOSASE (FRAGMENT) Mb0622 22 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 31794554 Common - hypothetical protein Mb3406 28 None None None 31793452 Pathogen - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2296 1 None None None 31793233 Common - hypothetical protein Mb2076 18 None None None 31794985 Common - hypothetical protein Mb3841 17 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 31793563 Common mbtI salicylate synthase MbtI Mb2407c 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 31793806 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2653c 6 None None None 31792260 Common - hypothetical protein Mb1098c 16 COG4425 COG4425, Predicted membrane protein Function unknown 31794325 Common nuoE NADH dehydrogenase subunit E Mb3173 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 31791299 Common fusA2a PROBABLE ELONGATION FACTOR G FUSA2A [FIRST PART] (EF-G) Mb0125c 176 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 31793104 Common lppC PROBABLE LIPOPROTEIN LPPC Mb1946c 105 COG1881 COG1881, Phospholipid-binding protein General function prediction only 31794491 Common - hypothetical protein Mb3339 5 None None None 31794038 Common mapB methionine aminopeptidase Mb2886c 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 31791773 Common mce2C MCE-FAMILY PROTEIN MCE2C Mb0606 10 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31793191 Common - hypothetical protein Mb2034c 17 COG1846 MarR, Transcriptional regulators Transcription 31792946 Common mmpL14 PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL14 Mb1787 39 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31792396 Common - hypothetical protein Mb1235c 3 None None None 31794453 Common - PROBABLE TRANSMEMBRANE CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) Mb3301 176 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 31792471 Common - PROBABLE DEHYDROGENASE FAD flavoprotein GMC oxidoreductase Mb1310 90 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 31794642 Pathogen - hypothetical protein Mb3495 1 None None None 31794484 Common - hypothetical protein Mb3332 22 None None None 31791436 Common - hypothetical protein Mb0264c 10 None None None 31792895 Common - PUTATIVE INITIATION INHIBITOR PROTEIN Mb1735 227 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 31794971 Common - PUTATIVE TRANSPOSASE [FIRST PART] Mb3827 31 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 31791453 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY) Mb0281c 5 COG1309 AcrR, Transcriptional regulator Transcription 31792818 Common - hypothetical protein Mb1658c 6 COG2306 COG2306, Uncharacterized conserved protein Function unknown 31794940 Pathogen - HYPOTHETICAL LEUCINE RICH PROTEIN Mb3796c 1 None None None 31791482 Common - PROBABLE DEHYDROGENASE/REDUCTASE Mb0311 82 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31792248 Common - hypothetical protein Mb1086 30 COG3391 COG3391, Uncharacterized conserved protein Function unknown 31794255 Common - hypothetical protein Mb3103 1 None None None 31793009 Common - PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER Mb1850c 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 31793764 Common hisS histidyl-tRNA synthetase Mb2611c 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31794949 Common - hypothetical protein Mb3805 4 None None None 31793794 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb2641c 8 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 31792913 Common - hypothetical protein Mb1754c 125 COG1733 COG1733, Predicted transcriptional regulators Transcription 31792539 Common lprD PROBABLE CONSERVED LIPOPROTEIN LPRD Mb1378c 6 COG4578 GutM, Glucitol operon activator Transcription 31793227 Common - hypothetical protein Mb2070c 16 None None None 31794967 Common embA INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE EMBA (ARABINOSYLINDOLYLACETYLINOSITOL SYNTHASE) Mb3823 5 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 31792157 Pathogen - hypothetical protein Mb0993 1 None None None 31791752 Common nrdZ PROBABLE RIBONUCLEOSIDE-DIPHOSPHATE REDUCTASE (LARGE SUBUNIT) NRDZ (RIBONUCLEOTIDE REDUCTASE) Mb0585 224 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 31792490 Common rho transcription termination factor Rho Mb1329 208 COG1158 Rho, Transcription termination factor Transcription 31793745 Common - PROBABLE GLUTAMINE-TRANSPORT TRANSMEMBRANE PROTEIN ABC TRANSPORTER Mb2592 14 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 31793035 Common - hypothetical protein Mb1876c 12 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 31794443 Common - PROBABLE DNA METHYLASE (MODIFICATION METHYLASE) (METHYLTRANSFERASE) Mb3291 25 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 31793202 Common - hypothetical protein Mb2045c 21 COG4683 COG4683, Uncharacterized protein conserved in bacteria Function unknown 31791532 Common PPE8 PPE FAMILY PROTEIN Mb0362c 28 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793976 Common - POSSIBLE HYDROLASE Mb2823 62 COG2936 COG2936, Predicted acyl esterases General function prediction only 31793991 Common - PROBABLE TRANSPOSASE Mb2839c 48 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 31792361 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1199c 30 COG1309 AcrR, Transcriptional regulator Transcription 31793478 Common - hypothetical protein Mb2322c 46 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 31794250 Common - hypothetical protein Mb3098 5 COG1993 COG1993, Uncharacterized conserved protein Function unknown 31793265 Pathogen - hypothetical protein Mb2108 1 COG5665 NOT5, CCR4-NOT transcriptional regulation complex, NOT5 subunit Transcription 31793799 Common thrS threonyl-tRNA synthetase Mb2646c 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31794231 Common nrdH PROBABLE GLUTAREDOXIN ELECTRON TRANSPORT COMPONENT OF NRDEF (GLUTAREDOXIN-LIKE PROTEIN) NRDH Mb3079c 37 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 31792693 Common lipL PROBABLE ESTERASE LIPL Mb1534 52 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 31792931 Common pknE PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE E PKNE (PROTEIN KINASE E) (STPK E) Mb1772 143 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 161511526 Common dxs2 1-deoxy-D-xylulose-5-phosphate synthase Mb3413c 202 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 31791653 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb0483 49 COG2733 COG2733, Predicted membrane protein Function unknown 31791504 Common - hypothetical protein Mb0333 40 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31792745 Common - hypothetical protein Mb1586 5 COG5450 COG5450, Transcription regulator of the Arc/MetJ class Transcription 31791885 Common rpsJ 30S ribosomal protein S10 Mb0720 246 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 31792169 Common rpmF 50S ribosomal protein L32 Mb1005 4 None None None 31791439 Common narK3 PROBABLE INTEGRAL MEMBRANE NITRITE EXTRUSION PROTEIN NARK3 (NITRITE FACILITATOR) Mb0267c 58 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 31793231 Common pks12 Probable polyketide synthase pks12 Mb2074c 222 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794667 Common - hypothetical protein Mb3521 1 None None None 31794809 Pathogen - hypothetical protein Mb3663c 1 None None None 161511534 Common kgd alpha-ketoglutarate decarboxylase Mb1280c 193 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 31793521 Common - hypothetical protein Mb2365c 7 None None None 31792267 Common lipU PUTATIVE LIPASE LIPU Mb1105 114 COG0657 Aes, Esterase/lipase Lipid metabolism 31791892 Common rpsC 30S ribosomal protein S3 Mb0727 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 31792686 Common - PROBABLE MEMBRANE PROTEIN Mb1527 1 None None None 31794801 Common - PUTATIVE TRANSFERASE (POSSIBLY GLYCOSYLTRANSFERASE) Mb3655 171 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 31791620 Common PPE10 PPE FAMILY PROTEIN Mb0450c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793627 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb2473c 2 None None None 31793299 Common - hypothetical protein Mb2143 27 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 31791829 Common mmaA1 METHOXY MYCOLIC ACID SYNTHASE 1 MMAA1 (METHYL MYCOLIC ACID SYNTHASE 1) (MMA1) (HYDROXY MYCOLIC ACID SYNTHASE) Mb0664c 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 31792480 Common - hypothetical protein Mb1319 48 COG0627 COG0627, Predicted esterase General function prediction only 31792798 Common trpB tryptophan synthase subunit beta Mb1638 225 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 31792965 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1805c 3 COG1309 AcrR, Transcriptional regulator Transcription 31794359 Common - hypothetical protein Mb3207c 1 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 31792760 Pathogen - Probable phiRV1 phage related protein Mb1600 1 None None None 31794653 Common - HYPOTHETICAL PROTEIN [FIRST PART] Mb3507 3 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 31795003 Common - PUTATIVE DEHYDROGENASE Mb3859c 74 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31792055 Common rpfA POSSIBLE RESUSCITATION-PROMOTING FACTOR RPFA Mb0891c 12 COG3456 COG3456, Uncharacterized conserved protein, contains FHA domain Signal transduction mechanisms 31793654 Common - POSSIBLE ALANINE AND PROLINE RICH MEMBRANE PROTEIN Mb2500 1 None None None 31794262 Common - PROBABLE MONOOXYGENASE (HYDROXYLASE) Mb3110 63 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 31792188 Pathogen - hypothetical protein Mb1024 1 None None None 31792751 Common - hypothetical protein Mb1592c 71 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 31793748 Common - LONG CONSERVED HYPOTHETICAL PROTEIN [FIRST PART] Mb2595 78 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 31793553 Common cfp2 LOW MOLECULAR WEIGHT ANTIGEN CFP2 (LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 2) (CFP-2) Mb2397c 1 None None None 31793952 Common - hypothetical protein Mb2799c 24 COG3687 COG3687, Predicted metal-dependent hydrolase General function prediction only 31792975 Common PPE25 PPE FAMILY PROTEIN Mb1815 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794743 Pathogen - hypothetical protein Mb3597c 1 None None None 31793327 Common - hypothetical protein Mb2171c 48 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 31794659 Common - hypothetical protein Mb3513c 2 None None None 31794105 Common tesA PROBABLE THIOESTERASE TESA Mb2953 49 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31792129 Common - POSSIBLE OXIDOREDUCTASE Mb0965c 53 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31792432 Common corA POSSIBLE MAGNESIUM AND COBALT TRANSPORT TRANSMEMBRANE PROTEIN CORA Mb1271c 173 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 31794209 Common - hypothetical protein Mb3057 36 COG1543 COG1543, Uncharacterized conserved protein Function unknown 31794445 Common wbbL1 PROBABLE dTDP-RHA:A-D-GlcNAc-DIPHOSPHORYL POLYPRENOL, A-3-L-RHAMNOSYL TRANSFERASE WBBL1 ALPHA-L-RHAMNOSE-(1->3)-ALPHA-D-GlcNAc(1->P)-P-DECAPRENYL) Mb3293c 122 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 31792200 Common rpfB Probable resuscitation-promoting factor rpfB Mb1036 25 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 31794379 Common - POSSIBLE ATP-DEPENDENT DNA HELICASE Mb3227c 26 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 31791313 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0140c 13 COG1309 AcrR, Transcriptional regulator Transcription 31794699 Common - acetyl-CoA acetyltransferase Mb3553 90 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31791817 Pathogen - hypothetical protein Mb0652 1 COG5450 COG5450, Transcription regulator of the Arc/MetJ class Transcription 31791282 Common - hypothetical protein Mb0107 17 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 31793125 Common fadE18 PROBABLE ACYL-COA DEHYDROGENASE FADE18 Mb1968c 133 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31794313 Common - PROBABLE MONOPHOSPHATASE Mb3161 175 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 31791276 Common - hypothetical protein Mb0101 2 None None None 31792708 Common mmpL12 PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL12 Mb1549c 85 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31793460 Pathogen - hypothetical protein Mb2304 1 None None None 31793687 Common - POSSIBLE CONSERVED PROLINE RICH MEMBRANE PROTEIN Mb2535 1 None None None 31792662 Pathogen PE_PGRS29 PE-PGRS FAMILY PROTEIN Mb1503c 1 None None None 31791861 Common mmpS5 POSSIBLE CONSERVED MEMBRANE PROTEIN MMPS5 Mb0696c 1 None None None 31792120 Common pstS2 PERIPLASMIC PHOSPHATE-BINDING LIPOPROTEIN PSTS2 (PBP-2) (PSTS2) Mb0956c 103 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 31794375 Common - POSSIBLE GLUTAREDOXIN PROTEIN Mb3223 20 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 31794681 Common fadE27 PROBABLE ACYL-COA DEHYDROGENASE FADE27 Mb3535 131 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31792883 Common - hypothetical protein Mb1723 19 COG4825 COG4825, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 31793181 Common - hypothetical protein Mb2024 3 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 31792935 Common - PROBABLE CONSERVED TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER Mb1776 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 31793044 Common ndh PROBABLE NADH DEHYDROGENASE NDH Mb1885c 173 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 31793305 Common - hypothetical protein Mb2149 22 COG1938 COG1938, Archaeal enzymes of ATP-grasp superfamily General function prediction only 31794121 Common - POSSIBLE TRANSPOSASE Mb2969 55 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 31792437 Common lpqZ PUTATIVE LIPOPROTEIN LPQZ Mb1276 11 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 31794989 Common - PUTATIVE ACYLTRANSFERASE Mb3845c 136 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 31794124 Common fadD22 acyl-CoA synthetase Mb2972c 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793843 Common ribD hypothetical protein Mb2690 110 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 31791289 Common - POSSIBLE TRANSMEMBRANE ACYLTRANSFERASE Mb0115 80 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 31791709 Common ccdA POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCDA Mb0540 77 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 31793180 Common - hypothetical protein Mb2023 4 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 31793195 Common - hypothetical protein Mb2038c 5 None None None 31794242 Common cstA PROBABLE CARBON STARVATION PROTEIN A HOMOLOG CSTA Mb3090 106 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 31793750 Common - CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN Mb2597 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 31791248 Common - POSSIBLE MATURASE Mb0072 84 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 31791923 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0758 14 COG1846 MarR, Transcriptional regulators Transcription 31792394 Common - PROBABLE TRANSFERASE Mb1233c 35 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 31793322 Pathogen - hypothetical protein Mb2166c 1 None None None 31791472 Common - hypothetical protein Mb0301c 4 COG1647 COG1647, Esterase/lipase General function prediction only 31791812 Common recBa PROBABLE EXONUCLEASE V (BETA CHAIN) RECBA [FIRST PART] (EXODEOXYRIBONUCLEASE V BETA CHAIN)(EXODEOXYRIBONUCLEASE V POLYPEPTIDE) Mb0647c 208 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 31794279 Common smpB SsrA-binding protein Mb3127c 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 31793156 Common yrbE3A CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE3A Mb1999 6 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 31794398 Common - PROBABLE TWO COMPONENT SENSOR KINASE Mb3246c 107 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 31793703 Common - hypothetical protein Mb2551c 156 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 31794188 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A Mb3036c 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 31791583 Common pks6b PROBABLE MEMBRANE BOUND POLYKETIDE SYNTHASE PKS6B [SECOND PART] Mb0413 208 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31791227 Common ponA1 PROBABLE BIFUNCTIONAL PENICILLIN-BINDING PROTEIN 1A/1B PONA1 (MUREIN POLYMERASE) (PBP1): PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE (PEPTIDOGLYCAN TGASE) + PENICILLIN-SENSITIVE TRANSPEPTIDASE (DD-TRANSPEPTIDASE) Mb0051 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 31794272 Common - HYPOTHETICAL OXIDOREDUCTASE Mb3120c 20 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31794405 Common - hypothetical protein Mb3253 7 COG2606 EbsC, Uncharacterized conserved protein Function unknown 31795026 Pathogen hns POSSIBLE HISTONE-LIKE PROTEIN HNS Mb3882 1 None None None 31791233 Common rplI 50S ribosomal protein L9 Mb0057 213 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 31794467 Common rsbW ANTI-SIGMA FACTOR RSBW (SIGMA NEGATIVE EFFECTOR) Mb3315c 11 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 31793985 Pathogen - hypothetical protein Mb2832 1 None None None 31794644 Common rmlB2 POSSIBLE DTDP-GLUCOSE 4,6-DEHYDRATASE RMLB2 Mb3497c 207 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 31791942 Common PPE12 PPE FAMILY PROTEIN Mb0777c 3 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792644 Pathogen PE_PGRS27 PE-PGRS FAMILY PROTEIN Mb1485c 1 None None None 31794628 Common cut3 PROBABLE CUTINASE PRECURSOR CUT3 Mb3481 3 None None None 31792444 Common - hypothetical protein Mb1283c 56 COG2251 COG2251, Predicted nuclease (RecB family) General function prediction only 31793595 Common - hypothetical protein Mb2439c 22 COG4552 Eis, Predicted acetyltransferase involved in intracellular survival and related acetyltransferases General function prediction only 31794434 Common - hypothetical protein Mb3282 23 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 31794933 Common lpqH 19 KDA LIPOPROTEIN ANTIGEN PRECURSOR LPQH Mb3789 1 None None None 31793481 Common - PROBABLE ANTIBIOTIC-RESISTANCE PROTEIN Mb2325c 52 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 31791635 Common - hypothetical protein Mb0465c 5 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 31793998 Common - hypothetical protein Mb2846c 4 None None None 31791244 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY) Mb0068c 39 COG1309 AcrR, Transcriptional regulator Transcription 31792668 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1509 7 None None None 31794181 Common cfp6 LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 6 (CFP-6) Mb3029 6 None None None 31791904 Common rpsH 30S ribosomal protein S8 Mb0739 247 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 31792724 Common ansA Probable L-aparaginase ansA Mb1565c 126 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 31792597 Common - PUTATIVE METHYLTRANSFERASE Mb1438c 36 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31792135 Common pgi glucose-6-phosphate isomerase Mb0971c 203 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 31791798 Pathogen - PROBABLE INTEGRAL MEMBRANE PROTEIN Mb0632 1 None None None 31791794 Pathogen - hypothetical protein Mb0628c 1 None None None 31791500 Common dcd deoxycytidine triphosphate deaminase Mb0329 160 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 31794013 Common dinF POSSIBLE DNA-DAMAGE-INDUCIBLE PROTEIN F DINF Mb2861c 38 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 31795014 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb3870 53 COG1316 LytR, Transcriptional regulator Transcription 31792246 Pathogen - POSSIBLE INTEGRASE (FRAGMENT) Mb1084 1 None None None 31791953 Common - short chain dehydrogenase Mb0788c 223 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 31793639 Common mmuM homocysteine methyltransferase Mb2485 159 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 31794899 Common - POSSIBLE OXIDOREDUCTASE Mb3754 7 COG3349 COG3349, Uncharacterized conserved protein Function unknown 31791853 Common - POSSIBLE HYDROLASE Mb0688c 12 None None None 31792213 Common lpqU PUTATIVE CONSERVED LIPOPROTEIN LPQU Mb1050 15 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 31794501 Common - hypothetical protein Mb3349c 8 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31791199 Pathogen whiB5 PUTATIVE TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB5 Mb0022c 1 None None None 31794689 Pathogen PE_PGRS57 PE-PGRS FAMILY PROTEIN Mb3543 1 None None None 31792861 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1702c 90 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 31792864 Common - HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN Mb1705 1 None None None 31795040 Common - hypothetical protein Mb3896 3 None None None 31792878 Common - PROBABLE PHOSPHATASE Mb1718 102 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 31794073 Common - hypothetical protein Mb2921c 187 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 31793546 Pathogen - hypothetical protein Mb2390c 1 None None None 31794980 Common - phosphoribose diphosphate:decaprenyl-phosphate phosphoribosyltransferase Mb3836c 61 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 31792529 Common - PROBABLE HYDROLASE Mb1368 50 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31794965 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3821 5 None None None 31794905 Common - hypothetical protein Mb3760c 20 COG4119 COG4119, Predicted NTP pyrophosphohydrolase DNA replication, recombination, and repair / General function prediction only 31794472 Common - hypothetical protein Mb3320 23 COG5383 COG5383, Uncharacterized protein conserved in bacteria Function unknown 31794703 Common - hypothetical protein Mb3557 5 None None None 31793019 Common - hypothetical protein Mb1860 75 COG1259 COG1259, Uncharacterized conserved protein Function unknown 31793178 Common - hypothetical protein Mb2021c 46 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 31792399 Common fadD6 acyl-CoA synthetase Mb1238 211 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31794386 Common TB9.4 hypothetical protein Mb3234c 15 None None None 31791363 Common - hypothetical protein Mb0191 2 None None None 31792725 Common lspA lipoprotein signal peptidase Mb1566 85 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 31792387 Common - hypothetical protein Mb1226c 15 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 31794202 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Mb3050c 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 31791722 Common - hypothetical protein Mb0554 10 COG3222 COG3222, Uncharacterized protein conserved in bacteria Function unknown 31792788 Common hisH imidazole glycerol phosphate synthase subunit HisH Mb1628 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 31793428 Common - hypothetical protein Mb2272 9 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 31794362 Common - hypothetical protein Mb3210 1 None None None 31792035 Common lpqS PROBABLE LIPOPROTEIN LPQS Mb0870 1 None None None 31793236 Common fxsA FxsA Mb2079c 1 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 31792833 Pathogen PE17 PE FAMILY PROTEIN Mb1673 1 None None None 31791736 Common bpoC POSSIBLE PEROXIDASE BPOC (NON-HAEM PEROXIDASE) Mb0569 153 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31794731 Common - hypothetical protein Mb3585c 8 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 31792732 Common - hypothetical protein Mb1573 4 None None None 31795067 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN [SECOND PART] Mb3923c 19 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 31793951 Common - PROBABLE OXIDOREDUCTASE Mb2798c 85 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 31793024 Common - Probable hydrolase Mb1865 16 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31794786 Common ftsH MEMBRANE-BOUND PROTEASE FTSH (CELL DIVISION PROTEIN) Mb3640c 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 31792545 Common - PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER Mb1384 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 31794719 Common fadE29 PROBABLE ACYL-COA DEHYDROGENASE FADE29 Mb3573c 156 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31795090 Common parB PROBABLE CHROMOSOME PARTITIONING PROTEIN PARB Mb3948c 183 COG1475 Spo0J, Predicted transcriptional regulators Transcription 31791616 Common moeA2 PROBABLE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MOEA2 Mb0446c 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 31792102 Common - acetyl-CoA acetyltransferase Mb0938c 107 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31791824 Common rplK 50S ribosomal protein L11 Mb0659 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 31793967 Common - PROBABLE TRANSPOSASE Mb2814c 55 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 31792804 Common tesB1 Probable acyl-CoA thioesterase II tesB1 Mb1644 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 31793420 Common - hypothetical protein Mb2264c 1 None None None 31793772 Common yajC preprotein translocase subunit YajC Mb2619c 9 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 31793114 Common - PROBABLE CONSERVED LIPOPROTEIN Mb1957 147 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 31793673 Common - hypothetical protein Mb2521 6 None None None 31793723 Pathogen - HYPOTHETICAL ALANINE RICH PROTEIN Mb2570 1 None None None 31792504 Common atpC F0F1 ATP synthase subunit epsilon Mb1343 130 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 31792567 Common - GLYCOLIPID SULFOTRANSFERASE [FIRST PART] Mb1407 8 None None None 31794723 Common - hypothetical protein Mb3577 11 None None None 31792462 Common lprA PUTATIVE LIPOPROTEIN LPRA Mb1301c 3 None None None 31791218 Common leuS leucyl-tRNA synthetase Mb0042 246 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31794054 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb2902c 6 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 31792839 Common argC N-acetyl-gamma-glutamyl-phosphate reductase Mb1680 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 31793708 Common - hypothetical protein Mb2556 1 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31792587 Common - PROBABLE MONOXYGENASE Mb1428c 77 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 31793402 Common glnA2 PROBABLE GLUTAMINE SYNTHETASE GLNA2 (GLUTAMINE SYNTHASE) (GS-II) Mb2246c 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 31794611 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb3464c 5 None None None 31794926 Common proZ POSSIBLE OSMOPROTECTANT (GLYCINE BETAINE/CARNITINE/CHOLINE/L-PROLINE) TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER PROZ Mb3782c 59 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 31793135 Common - hypothetical protein Mb1978c 1 None None None 31793432 Common - diacylglycerol kinase Mb2276 106 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 31794790 Common - hypothetical protein Mb3644c 1 None None None 31793242 Common - hypothetical protein Mb2085 80 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 31792761 Pathogen - Probable phiRV1 phage protein Mb1601 1 None None None 31793374 Common qcrA Probable Rieske iron-sulfur protein QcrA Mb2218 27 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 31792613 Pathogen - hypothetical protein Mb1454 1 None None None 31791561 Common clpB PROBABLE ENDOPEPTIDASE ATP BINDING PROTEIN (CHAIN B) CLPB (CLPB PROTEIN) (HEAT SHOCK PROTEIN F84.1) Mb0391c 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 31794543 Common - hypothetical protein Mb3395 7 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 31792770 Common - Possible phiRv1 phage protein Mb1610c 1 None None None 31791354 Common - PROBABLE CONSERVED MCE ASSOCIATED TRANSMEMBRANE PROTEIN Mb0182 4 COG1714 COG1714, Predicted membrane protein/domain Function unknown 31791602 Common - hypothetical protein Mb0432c 3 None None None 31794575 Common - hypothetical protein Mb3427c 9 None None None 31794958 Pathogen - hypothetical protein Mb3814 1 None None None 31795083 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3940 154 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 31794311 Common PPE50 PPE FAMILY PROTEIN Mb3159 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793278 Common - hypothetical protein Mb2122c 26 COG2378 COG2378, Predicted transcriptional regulator Transcription 31791917 Common - hypothetical protein Mb0752c 19 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31791263 Common hycP POSSIBLE HYDROGENASE HYCP Mb0088 23 COG4237 HyfE, Hydrogenase 4 membrane component (E) Energy production and conversion 31791609 Common - PUTATIVE TUBERCULIN RELATED PEPTIDE Mb0439 3 None None None 31794214 Common TB22.2 PROBABLE CONSERVED SECRETED PROTEIN TB22.2 Mb3062c 1 None None None 31794147 Common - hypothetical protein Mb2995 23 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 31793287 Pathogen PE22 conserved hypothetical protein, PE Mb2131 1 None None None 31793471 Common - hypothetical protein Mb2315c 6 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 31791937 Pathogen - hypothetical protein Mb0772 1 None None None 31794504 Common moaX PROBABLE MOAD-MOAE FUSION PROTEIN MOAX Mb3352c 132 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 31793645 Common - POSSIBLE DNA GLYCOSYLASE Mb2491c 178 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 31792823 Common - hypothetical protein Mb1663c 178 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 31792633 Pathogen - hypothetical protein Mb1474c 1 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 31793416 Common cobD cobalamin biosynthesis protein Mb2260c 151 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 31791851 Common rpoB DNA-directed RNA polymerase subunit beta Mb0686 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 31792224 Common trcS TWO COMPONENT SENSOR HISTIDINE KINASE TRCS Mb1061c 213 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 31792915 Common - hypothetical protein Mb1756 9 None None None 31792806 Common cydC PROBABLE 'COMPONENT LINKED WITH THE ASSEMBLY OF CYTOCHROME' TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER CYDC Mb1646c 238 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 31791373 Common - PUTATIVE TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LUXR-FAMILY) Mb0201 19 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 31792543 Common - hypothetical protein Mb1382c 41 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 31793045 Common - POSSIBLE OXIDOREDUCTASE Mb1886c 57 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31792418 Common - hypothetical protein Mb1257c 102 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 31794601 Common rimI PROBABLE RIBOSOMAL-PROTEIN-ALANINE ACETYLTRANSFERASE RIMI (ACETYLATING ENZYME FOR N-TERMINAL OF RIBOSOMAL PROTEIN S18) Mb3454c 62 COG0456 RimI, Acetyltransferases General function prediction only 31792450 Common - hypothetical protein Mb1289 68 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 31792628 Pathogen - hypothetical protein Mb1469 1 None None None 31794060 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb2908 201 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31791309 Common - hypothetical protein Mb0135 77 COG2030 MaoC, Acyl dehydratase Lipid metabolism 31792954 Common - PUTATIVE TRANSPOSASE (FRAGMENT) Mb1795c 65 None None None 31793868 Common - CONSERVED HYPOTHETICAL ALANINE AND GLYCINE AND VALINE RICH PROTEIN Mb2715c 19 None None None 31793353 Common - conserved hypothetical regulatory protein Mb2197c 15 None None None 31792093 Common echA6 enoyl-CoA hydratase Mb0929 180 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31792678 Common fabG1 PROBABLE 3-OXOACYL-[ACYL-CARRIER PROTEIN] REDUCTASE FABG1 (3-KETOACYL-ACYL CARRIER PROTEIN REDUCTASE) Mb1519 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31793310 Common cysS cysteinyl-tRNA synthetase Mb2154c 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31794768 Common - PUTATIVE HYDROLASE Mb3622c 77 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31792285 Common coaA pantothenate kinase Mb1122c 72 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 31794334 Common nuoN NADH dehydrogenase subunit N Mb3182 208 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 31792486 Common lysA PROBABLE DIAMINOPIMELATE DECARBOXYLASE LYSA (DAP DECARBOXYLASE) Mb1325 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 31791590 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb0420c 6 None None None 31793318 Common lppL Probable conserved lipoprotein LppL Mb2162 5 None None None 31794091 Common - hypothetical protein Mb2939c 69 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 31791300 Common - hypothetical protein Mb0126c 8 None None None 31791759 Common TB27.3 hypothetical protein Mb0592 40 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 31794825 Common - hypothetical protein Mb3679c 3 None None None 31793711 Common - hypothetical protein Mb2559c 8 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31792684 Common - hypothetical protein Mb1525 1 None None None 31793635 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta Mb2481c 117 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 31791832 Common - ALPHA-MANNOSIDASE Mb0667 45 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 31791204 Pathogen - hypothetical protein Mb0028 1 None None None 31792199 Common tatD Probable deoxyribonuclease TatD (YjjV protein) Mb1035 234 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 31791438 Common - bifunctional uroporphyrinogen-III synthetase/response regulator domain protein Mb0266c 21 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 31794850 Common - PROBABLE ANION TRANSPORTER ATPASE Mb3704 42 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 31792040 Common fadD16 POSSIBLE FATTY-ACID-COA LIGASE FADD16 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-COA SYNTHASE) Mb0875 1 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 31791675 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY) Mb0505 132 COG2186 FadR, Transcriptional regulators Transcription 31792191 Common - hypothetical protein Mb1027c 37 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 31791399 Common - hypothetical protein Mb0227 27 None None None 31791931 Common - hypothetical protein Mb0766 6 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 31791993 Common - hypothetical protein Mb0828 92 COG1409 Icc, Predicted phosphohydrolases General function prediction only 31791750 Common cyp135B1 POSSIBLE CYTOCHROME P450 135B1 CYP135B1 Mb0583 76 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31792275 Common - hypothetical protein Mb1113 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 31793792 Common pdxH pyridoxamine 5'-phosphate oxidase Mb2639 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 31794106 Pathogen - hypothetical protein Mb2954 1 None None None 31793341 Common - hypothetical protein Mb2185c 17 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31793822 Common - hypothetical protein Mb2669 10 COG3896 COG3896, Chloramphenicol 3-O-phosphotransferase Defense mechanisms 31792172 Common mprB PROBABLE TWO COMPONENT SENSOR KINASE MPRB Mb1008 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 31794698 Common - lipid-transfer protein Mb3552 50 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31794583 Common - CONSERVED HYPOTHETICAL PROTEIN [FIRST PART] Mb3436c 187 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 31792623 Common - hypothetical protein Mb1464 12 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 31794193 Common lpqA PROBABLE LIPOPROTEIN LPQA Mb3041 1 None None None 31792548 Common - hypothetical protein Mb1387 1 None None None 31792316 Common gnd2 6-phosphogluconate dehydrogenase-like protein Mb1153 183 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 31791839 Common mkl POSSIBLE RIBONUCLEOTIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER MKL Mb0674 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 31791237 Common - hypothetical protein Mb0061 35 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 31792241 Common - PROBABLE OXIDOREDUCTASE Mb1079 234 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 31792607 Common - hypothetical protein Mb1448 14 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 31794595 Common sigD RNA polymerase sigma factor SigD Mb3448c 14 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 31792635 Pathogen PE_PGRS26 PE-PGRS FAMILY PROTEIN Mb1476c 1 None None None 31793095 Common nanT PROBABLE SIALIC ACID-TRANSPORT INTEGRAL MEMBRANE PROTEIN NANT Mb1937c 184 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31793074 Common - hypothetical protein Mb1915c 8 None None None 31793939 Common thyA thymidylate synthase Mb2786c 139 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 31794796 Common - hypothetical protein Mb3650c 23 COG5282 COG5282, Uncharacterized conserved protein Function unknown 31791498 Common pcp pyrrolidone-carboxylate peptidase Mb0327 55 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 31794159 Common - CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN Mb3007 14 COG1920 COG1920, Uncharacterized conserved protein Function unknown 31793146 Pathogen - hypothetical protein Mb1989c 1 None None None 31791328 Pathogen - hypothetical protein Mb0155c 1 None None None 31794830 Common - hypothetical protein Mb3684c 12 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 31792279 Common - hypothetical protein Mb1116A 19 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 31793507 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ASNC-FAMILY) Mb2351 153 COG1522 Lrp, Transcriptional regulators Transcription 31793920 Common pgsA3 PROBABLE PGP SYNTHASE PGSA3 (CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE) (PHOSPHATIDYLGLYCEROPHOSPHATE SYNTHASE) Mb2767c 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 31791949 Common adhB POSSIBLE ZINC-CONTAINING ALCOHOL DEHYDROGENASE NAD DEPENDANT ADHB Mb0784c 206 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 31791349 Common mce1C MCE-FAMILY PROTEIN MCE1C Mb0177 8 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31791645 Common - hypothetical protein Mb0475 4 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 31792457 Common - hypothetical protein Mb1296 7 None None None 31792109 Common - POSSIBLE RESOLVASE Mb0945 22 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 31792352 Common pimE mannosyltransferase Mb1190 18 None None None 31791551 Common - PROBABLE CARBON MONOXYDE DEHYDROGENASE (SMALL CHAIN) Mb0381c 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 31791599 Common - hypothetical protein Mb0429c 34 COG3571 COG3571, Predicted hydrolase of the alpha/beta-hydrolase fold General function prediction only 31791746 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Mb0579c 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 31794424 Common lpqB PROBABLE CONSERVED LIPOPROTEIN LPQB Mb3272c 17 None None None 31793206 Common - hypothetical protein Mb2049c 65 COG4889 COG4889, Predicted helicase General function prediction only 31792616 Common - hypothetical protein Mb1457 89 COG0391 COG0391, Uncharacterized conserved protein Function unknown 31791513 Pathogen PE6 PE FAMILY PROTEIN Mb0342c 1 None None None 31792527 Common clpS ATP-dependent Clp protease adaptor protein ClpS Mb1366 16 COG2127 COG2127, Uncharacterized conserved protein Function unknown 31793716 Common efp elongation factor P Mb2563c 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 31793273 Common - 5'-3' exonuclease Mb2117 216 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 31794482 Common glpD2 PROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLPD2 Mb3330c 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 31793910 Common - CONSERVED HYPOTHETICAL CYSTEINE RICH PROTEIN (FRAGMENT) Mb2757 4 COG4114 FhuF, Uncharacterized Fe-S protein General function prediction only 31793525 Pathogen PE_PGRS39 PE-PGRS FAMILY PROTEIN Mb2369c 1 None None None 31795076 Common - HYPOTHETICAL ALANINE AND PROLINE RICH PROTEIN Mb3933c 5 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 31794150 Common recG PROBABLE ATP-DEPENDENT DNA HELICASE RECG Mb2998c 212 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 31794036 Common - POSSIBLE AMIDOTRANSFERASE Mb2884c 124 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 31791433 Common cobQ1 cobyric acid synthase Mb0261c 150 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 31793291 Common - hypothetical protein Mb2135c 3 None None None 31792657 Common - PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER Mb1498 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 31792857 Common - HYPOTHETICAL MEMBRANE PROTEIN Mb1698 2 None None None 31792987 Pathogen lppT PROBABLE LIPOPROTEIN LPPT Mb1827 1 None None None 31791627 Common - hypothetical protein Mb0457c 66 COG2907 COG2907, Predicted NAD/FAD-binding protein General function prediction only 31794320 Pathogen PPE52 PPE-FAMILY PROTEIN Mb3168c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794298 Pathogen - hypothetical protein Mb3146 1 None None None 31792777 Common - PROBABLE TRANSMEMBRANE PROTEIN Mb1617 1 None None None 31792148 Common - hypothetical protein Mb0984 20 COG4867 COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain General function prediction only 31794513 Common sigJ RNA polymerase sigma factor SigJ Mb3361c 52 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 31792296 Pathogen - hypothetical protein Mb1133c 1 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 31793895 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb2742 92 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 31792835 Common - Probable transmembrane protein Mb1675 1 None None None 31793607 Common proA gamma-glutamyl phosphate reductase Mb2451c 189 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 31791876 Common - hypothetical protein Mb0711 5 None None None 31792050 Common - hypothetical protein Mb0885c 15 COG2378 COG2378, Predicted transcriptional regulator Transcription 31792900 Common engA GTP-binding protein EngA Mb1740 228 COG1160 COG1160, Predicted GTPases General function prediction only 31794923 Common - hypothetical protein Mb3779c 9 None None None 31791324 Common - hypothetical protein Mb0151 27 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31792429 Common sugA PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGA Mb1268 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 31793119 Common - hypothetical protein Mb1962 16 COG3361 COG3361, Uncharacterized conserved protein Function unknown 31793200 Common - hypothetical protein Mb2043c 23 COG4889 COG4889, Predicted helicase General function prediction only 31792470 Common - hypothetical protein Mb1309 6 COG4717 COG4717, Uncharacterized conserved protein Function unknown 31793978 Common - HYPOTHETICAL ARGININE AND ALANINE RICH PROTEIN Mb2825c 5 COG5586 COG5586, Uncharacterized conserved protein Function unknown 31792847 Common pks10 Possible chalcone synthase pks10 Mb1688 38 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 31795085 Common - HYPOTHETICAL ALANINE RICH PROTEIN Mb3943 1 None None None 31793447 Common cyp128 PROBABLE CYTOCHROME P450 128 CYP128 Mb2291c 75 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31793808 Common - POSSIBLE METHYLTRANSFERASE (METHYLASE) Mb2655 21 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31794842 Common - hypothetical protein Mb3696c 114 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 31791966 Common cyp126 POSSIBLE CYTOCHROME P450 126 CYP126 Mb0801 68 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31792928 Common - hypothetical protein Mb1769 6 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 31793134 Common - hypothetical protein Mb1977c 3 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 31791535 Common - hypothetical protein Mb0365 5 None None None 31793394 Common dlaT dihydrolipoamide acetyltransferase Mb2238 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 31793565 Common hemN coproporphyrinogen III oxidase Mb2409c 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 31792003 Common cysA2 PROBABLE THIOSULFATE SULFURTRANSFERASE CYSA2 (RHODANESE-LIKE PROTEIN) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE) Mb0838c 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 31793303 Common PPE37 conserved hypothetical protein, PPE Mb2147 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792602 Common rpe ribulose-phosphate 3-epimerase Mb1443 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 31793813 Common - hypothetical protein Mb2660c 4 None None None 31794983 Common glf UDP-GALACTOPYRANOSE MUTASE GLF (UDP-GALP MUTASE) (NAD+-FLAVIN ADENINE DINUCLEOTIDE-REQUIRING ENZYME) Mb3839c 54 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 31791710 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0541 18 COG1333 ResB, ResB protein required for cytochrome c biosynthesis Posttranslational modification, protein turnover, chaperones 31791216 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb0040c 1 None None None 31793992 Common - hypothetical protein Mb2840c 13 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 31792235 Common - hypothetical protein Mb1073 3 COG5340 COG5340, Predicted transcriptional regulator Transcription 31794223 Common adhC PROBABLE NADP-DEPENDENT ALCOHOL DEHYDROGENASE ADHC Mb3071 206 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 31793430 Common - Possible transcriptional regulatory protein Mb2274c 18 COG1309 AcrR, Transcriptional regulator Transcription 31792155 Common - hypothetical protein Mb0991c 14 None None None 31792473 Common oppD PROBABLE OLIGOPEPTIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER OPPD Mb1312c 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 31793454 Common - hypothetical protein Mb2298 3 None None None 31794552 Common - hypothetical protein Mb3404 5 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 31794635 Common rpsK 30S ribosomal protein S11 Mb3488c 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 31794528 Pathogen PE_PGRS50a PE-PGRS FAMILY PROTEIN [FIRST PART] Mb3377c 1 None None None 31794708 Common PPE61 PPE FAMILY PROTEIN Mb3562 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794521 Common trpS tryptophanyl-tRNA synthetase Mb3369c 230 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31795037 Common - HYPOTHETICAL ALANINE RICH PROTEIN Mb3893 1 None None None 31794022 Common proS prolyl-tRNA synthetase Mb2870c 222 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31791335 Common pntB PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT BETA) PNTB [INTEGRAL MEMBRANE PROTEIN] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT BETA) (NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT BETA) Mb0162 122 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 31791356 Common - PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN Mb0184 1 None None None 31793439 Common adhE2 Probable zinc-dependent alcohol dehydrogenase AdhE2 Mb2283 209 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 31791625 Common ufaA1 PUTATIVE CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE UFAA1 (CYCLOPROPANE FATTY ACID SYNTHASE) (CFA SYNTHASE) Mb0455c 124 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 31791698 Common - hypothetical protein Mb0529c 1 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 31791778 Common - hypothetical protein Mb0612c 2 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 31792024 Common - hypothetical protein Mb0859c 7 COG4849 COG4849, Uncharacterized protein conserved in bacteria Function unknown 31791209 Common bioF2 POSSIBLE 8-AMINO-7-OXONONANOATE SYNTHASE BIOF2 (AONS) (8-AMINO-7-KETOPELARGONATE SYNTHASE) (7-KETO-8-AMINO-PELARGONIC ACID SYNTHETASE) (7-KAP SYNTHETASE) (L-ALANINE--PIMELYL CoA LIGASE) Mb0033 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 31792850 Common pks17 Probable polyketide synthase pks17 Mb1691 75 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31794327 Common nuoG NADH dehydrogenase subunit G Mb3175 189 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 31792840 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Mb1681 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 31794049 Common - hypothetical protein Mb2897 4 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794784 Common folP1 DIHYDROPTEROATE SYNTHASE 1 FOLP (DHPS 1) (DIHYDROPTEROATE PYROPHOSPHORYLASE 1) (DIHYDROPTEROATE DIPHOSPHORYLASE 1) Mb3638c 216 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 31794535 Common - POSSIBLE OXIDOREDUCTASE Mb3387c 21 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 31793664 Common lipQ PROBABLE CARBOXYLESTERASE LIPQ Mb2510c 66 COG0657 Aes, Esterase/lipase Lipid metabolism 31794282 Common - HYPOTHETICAL PROLINE-RICH PROTEIN Mb3130c 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 31793766 Common ppiB PROBABLE PEPTIDYL-PROLYL CIS-TRANS ISOMERASE B PPIB (CYCLOPHILIN) (PPIASE) (ROTAMASE) (PEPTIDYLPROLYL ISOMERASE) Mb2613 100 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 31794969 Common - hypothetical protein Mb3825 82 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 31792944 Common - hypothetical protein Mb1785c 182 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 31794916 Common PE34 PROBABLE PE FAMILY PROTEIN Mb3772c 1 None None None 31793225 Common - hypothetical protein Mb2068c 4 None None None 31794911 Common - POSSIBLE OXIDOREDUCTASE Mb3767c 31 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 31792309 Pathogen - hypothetical protein Mb1146 1 None None None 31791745 Common htpX heat shock protein HtpX Mb0578 192 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 31794079 Common lepB PROBABLE SIGNAL PEPTIDASE I LEPB (SPASE I) (LEADER PEPTIDASE I). Mb2927c 164 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 31793003 Common erg3 MEMBRANE-BOUND C-5 STEROL DESATURASE ERG3 (STEROL-C5-DESATURASE) Mb1844 68 COG3000 ERG3, Sterol desaturase Lipid metabolism 31791456 Pathogen PE_PGRS3a PE-PGRS FAMILY PROTEIN [FIRST PART] Mb0285c 1 None None None 31792897 Common - hypothetical protein Mb1737 147 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 31793929 Common hsdS' POSSIBLE TYPE I RESTRICTION/MODIFICATION SYSTEM SPECIFICITY DETERMINANT (FRAGMENT) HSDS' (S PROTEIN) Mb2776c 27 None None None 31792511 Common alkAb PUTATIVE ADA REGULATORY PROTEIN ALKAb [SECOND PART] (Regulatory protein of adaptative response) : Methylated-DNA--protein-cysteine methyltransferase (O-6-methylguanine-DNA alkyltransferase) Mb1350c 97 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 31794839 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3693 12 None None None 31791484 Common PPE6 PPE FAMILY PROTEIN Mb0313c 19 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792218 Common kdpE PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN KDPE Mb1055c 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31793033 Common guaB1 inositol-5-monophosphate dehydrogenase Mb1874c 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 31792744 Common ilvA threonine dehydratase Mb1585 193 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 31793841 Common - hypothetical protein Mb2688 52 COG0456 RimI, Acetyltransferases General function prediction only 31794935 Common - PUTATIVE TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN Mb3791c 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31793878 Pathogen - hypothetical protein Mb2725c 1 None None None 31791530 Common dnaJ1 PROBABLE CHAPERONE PROTEIN DNAJ1 Mb0360 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 31794943 Common - hypothetical protein Mb3799c 2 None None None 31794070 Common xerC site-specific tyrosine recombinase XerC Mb2918c 221 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 31792363 Pathogen PE11 PE FAMILY PROTEIN Mb1202c 1 None None None 31791424 Pathogen - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0252 1 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 31793408 Common - conserved hypothetical protein [SECOND PART] Mb2252 24 COG3826 COG3826, Uncharacterized protein conserved in bacteria Function unknown 31793007 Common - hypothetical protein Mb1848 58 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 31791467 Common esxH LOW MOLECULAR WEIGHT PROTEIN ANTIGEN 7 CFP7 (10 kDa ANTIGEN) (CFP-7) (PROTEIN TB10.4) Mb0296 2 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31792065 Common - hypothetical protein Mb0901 18 None None None 31794951 Common - POSSIBLE AMINOTRANSFERASE Mb3807c 197 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 31793833 Pathogen - hypothetical protein Mb2680 1 None None None 31793397 Common lipA lipoyl synthase Mb2241 191 COG0320 LipA, Lipoate synthase Coenzyme metabolism 31791970 Common emrB POSSIBLE MULTIDRUG RESISTANCE INTEGRAL MEMBRANE EFFLUX PROTEIN EMRB Mb0805c 197 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31794346 Common - hypothetical protein Mb3194 12 None None None 31793747 Common - hypothetical protein Mb2594 139 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 31793083 Common - hypothetical protein Mb1924 1 None None None 31793330 Common ftsZ cell division protein FtsZ Mb2174c 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 31793491 Common - POSSIBLE INTEGRASE (FRAGMENT) Mb2335c 81 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 31792611 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb1452 9 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 31793940 Common - PROBABLE ALANINE RICH HYDROLASE Mb2787 97 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 31794045 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase Mb2893c 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 31794451 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb3299c 10 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 31794897 Common - PUTATIVE OXIDOREDUCTASE Mb3752 93 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 31791800 Common - hypothetical protein Mb0634 4 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794176 Common lppY PROBABLE CONSERVED LIPOPROTEIN LPPY Mb3024 16 None None None 31793063 Common - hypothetical protein Mb1904 28 COG5579 COG5579, Uncharacterized conserved protein Function unknown 31791506 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR/ACRR-FAMILY) Mb0335 73 COG1309 AcrR, Transcriptional regulator Transcription 31794391 Common - POSSIBLE SOJ/PARA-RELATED PROTEIN Mb3239c 226 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 31792304 Common - hypothetical protein Mb1141c 3 None None None 31794673 Common mce4C MCE-FAMILY PROTEIN MCE4C Mb3527c 27 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31792190 Common - hypothetical protein Mb1026 1 None None None 31793365 Common - hypothetical protein Mb2209 20 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 31792343 Common - POSSIBLE TRANSPOSASE Mb1180 72 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 31792771 Pathogen - Possible phage phiRv1 protein Mb1611c 1 None None None 31792550 Common - hypothetical protein Mb1389c 175 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 31793467 Common cdh CDP-diacylglycerol pyrophosphatase Mb2311 18 COG2134 Cdh, CDP-diacylglycerol pyrophosphatase Lipid metabolism 31792057 Common moaA molybdenum cofactor biosynthesis protein A Mb0893c 194 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 31795061 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3917c 1 None None None 31792331 Common - POSSIBLE ENOYL-COA HYDRATASE Mb1168 148 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31792150 Pathogen - PROBABLE INTEGRAL MEMBRANE PROTEIN Mb0986 1 None None None 31791844 Pathogen - hypothetical protein Mb0679c 1 None None None 31793515 Pathogen - hypothetical protein Mb2359 1 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 31793256 Common cobLa Probable precorrin-6y methyltransferase CobLa [FIRST PART] Mb2099c 3 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 31793883 Common ideR IRON-DEPENDENT REPRESSOR AND ACTIVATOR IDER Mb2730 83 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 31794291 Common moaD1 PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN D MOAD1 (MOLYBDOPTERIN CONVERTING FACTOR SMALL SUBUNIT) (MOLYBDOPTERIN [MPT] CONVERTING FACTOR, SUBUNIT 1) Mb3139 16 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 31792402 Common - hypothetical protein Mb1241 1 None None None 31793026 Common - hypothetical protein Mb1867c 8 None None None 31793378 Common - Possible conserved integral membrane protein Mb2222c 18 None None None 31792562 Common - hypothetical protein Mb1401 5 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 31792582 Common mihF PUTATIVE INTEGRATION HOST FACTOR MIHF Mb1423 16 None None None 31794164 Common leuC isopropylmalate isomerase large subunit Mb3012c 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 31793760 Pathogen - CONSERVED HYPOTHETICAL PROTEIN [FIRST PART] Mb2607 1 None None None 31791765 Common lpqN PROBABLE CONSERVED LIPOPROTEIN LPQN Mb0598c 1 None None None 31794003 Pathogen - hypothetical protein Mb2851c 1 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 31791842 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0677c 2 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 31792491 Common rpmE 50S ribosomal protein L31 Mb1330 202 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 31792374 Common pks3 PROBABLE POLYKETIDE BETA-KETOACYL SYNTHASE PKS3 Mb1213 215 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794978 Common fbpA SECRETED ANTIGEN 85-A FBPA (MYCOLYL TRANSFERASE 85A) (FIBRONECTIN-BINDING PROTEIN A) (ANTIGEN 85 COMPLEX A) Mb3834c 8 COG0627 COG0627, Predicted esterase General function prediction only 31792518 Common - hypothetical protein Mb1357c 91 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 31794094 Common glnD PII uridylyl-transferase Mb2942c 125 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 31795073 Pathogen - CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN Mb3930c 1 None None None 31794127 Common - POSSIBLE OXIDOREDUCTASE Mb2975c 33 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31791730 Common menB naphthoate synthase Mb0562c 176 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 31794566 Common - POSSIBLE TRANSPOSASE Mb3418 8 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 31792409 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb1248c 27 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 31793410 Common - hypothetical protein Mb2254c 17 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 31791311 Common fgd2 PUTATIVE F420-DEPENDANT GLUCOSE-6-PHOSPHATE DEHYDROGENASE FGD2 Mb0137c 81 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31791294 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb0120c 27 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 31791180 Common recF recombination protein F Mb0003 163 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 31794308 Common devS TWO COMPONENT SENSOR HISTIDINE KINASE DEVS Mb3156c 144 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 31791325 Common - PROBABLE ALDEHYDE DEHYDROGENASE (NAD+) DEPENDANT Mb0152 217 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 31792408 Common - hypothetical protein Mb1247c 59 COG2936 COG2936, Predicted acyl esterases General function prediction only 31794906 Common - hypothetical protein Mb3761c 28 None None None 31793183 Common - hypothetical protein Mb2026c 44 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31793213 Common - CONSERVED HYPOTHETICAL PROTEIN [FIRST PART] Mb2056c 78 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 31793246 Pathogen - hypothetical protein Mb2089 1 None None None 31793621 Common obgE GTPase ObgE Mb2467c 249 COG0536 Obg, Predicted GTPase General function prediction only 31793379 Common ctaC PROBABLE TRANSMEMBRANE CYTOCHROME C OXIDASE (SUBUNIT II) CTAC Mb2223c 130 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 31792849 Common pks8 Probable polyketide synthase pks8 Mb1690 216 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31792767 Pathogen - Probable phiRv1 phage protein Mb1607c 1 None None None 31792494 Common - hypothetical protein Mb1333 235 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 31791544 Common - hypothetical protein Mb0374c 4 None None None 31794758 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Mb3612c 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 31793954 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LRP/ASNC-FAMILY) Mb2801c 146 COG1522 Lrp, Transcriptional regulators Transcription 31794697 Common - hypothetical protein Mb3551 19 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 31793340 Common - hypothetical protein Mb2184c 27 COG1309 AcrR, Transcriptional regulator Transcription 31793628 Common folC PROBABLE FOLYLPOLYGLUTAMATE SYNTHASE PROTEIN FOLC (FOLYLPOLY-GAMMA-GLUTAMATE SYNTHETASE) (FPGS) Mb2474c 211 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 31794095 Common glnB PROBABLE NITROGEN REGULATORY PROTEIN P-II GLNB Mb2943c 187 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 31794812 Common - hypothetical protein Mb3666c 1 None None None 31793706 Common - hypothetical protein Mb2554c 4 None None None 31793469 Pathogen lppOb Probable conserved lipoprotein lppOb Mb2313 1 None None None 31791404 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb0232c 8 None None None 31794018 Common nusA transcription elongation factor NusA Mb2866c 225 COG0195 NusA, Transcription elongation factor Transcription 31791980 Common - hypothetical protein Mb0815c 102 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31791652 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY) Mb0482c 13 COG1309 AcrR, Transcriptional regulator Transcription 31793383 Common - hypothetical protein Mb2227c 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 31791238 Pathogen - hypothetical protein Mb0062 1 None None None 31791720 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb0552 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 31792660 Common - hypothetical protein Mb1501 75 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 31794421 Common - hypothetical protein Mb3269c 81 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 31793194 Common - POSSIBLE TRANSPOSASE Mb2037 24 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 31792867 Common moeX POSSIBLE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MOEX Mb1708 122 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 31791225 Common - POSSIBLE MEMBRANE PROTEIN Mb0049c 5 None None None 31793559 Common mbtC POLYKETIDE SYNTHETASE MBTC (POLYKETIDE SYNTHASE) Mb2403c 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31792320 Common - hypothetical protein Mb1157c 7 None None None 31794726 Common echA20 enoyl-CoA hydratase Mb3580 144 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31792317 Common bpoB POSSIBLE PEROXIDASE BPOB (NON-HAEM PEROXIDASE) Mb1154c 47 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31794051 Common dipZ POSSIBLE INTEGRAL MEMBRANE C-TYPE CYTOCHROME BIOGENESIS PROTEIN DIPZ Mb2899 87 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 31794058 Common frr ribosome recycling factor Mb2906c 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 31792631 Common pgk phosphoglycerate kinase Mb1472 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 31794052 Common mpb70 MAJOR SECRETED IMMUNOGENIC PROTEIN MPB70 PRECURSOR Mb2900 68 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 31793297 Common - hypothetical protein Mb2141 32 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 31794186 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Mb3034c 212 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 31792233 Common - PUTATIVE IS LIKE-2 TRANSPOSASE Mb1071c 72 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 31793372 Common ctaE PROBABLE CYTOCHROME C OXIDASE (SUBUNIT III) CTAE Mb2216 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 31791646 Common icl isocitrate lyase Mb0476 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 31794425 Common mtrB TWO COMPONENT SENSORY TRANSDUCTION HISTIDINE KINASE MTRB Mb3273c 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 31794353 Pathogen mesTb PROBABLE EPOXIDE HYDROLASE MESTB [SECOND PART] (EPOXIDE HYDRATASE) (ARENE-OXIDE HYDRATASE) Mb3201c 2 None None None 31793145 Common - hypothetical protein Mb1988 26 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794330 Common nuoJ NADH dehydrogenase subunit J Mb3178 35 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 31792214 Common eno phosphopyruvate hydratase Mb1051 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 31793942 Pathogen - POSSIBLE MEMBRANE PROTEIN Mb2789c 1 None None None 31792325 Common gltA1 methylcitrate synthase Mb1162 194 COG0372 GltA, Citrate synthase Energy production and conversion 31794335 Common PPE53 PPE FAMILY PROTEIN Mb3183c 9 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793675 Common pdhC branched-chain alpha-keto acid dehydrogenase subunit E2 Mb2523c 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 31794493 Pathogen - SECRETED PROTEIN ANTIGEN Mb3341c 1 None None None 31793506 Common - hypothetical protein Mb2350c 39 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 31794976 Common - hypothetical protein Mb3832c 4 None None None 31793085 Pathogen - hypothetical protein Mb1926 1 None None None 31792866 Common - hypothetical protein Mb1707 32 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 31791580 Common mmpS1 PROBABLE CONSERVED MEMBRANE PROTEIN MMPS1 Mb0410c 1 None None None 31792599 Common - PUTATIVE METHYLTRANSFERASE Mb1440c 173 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31794791 Pathogen - hypothetical protein Mb3645c 1 None None None 31794672 Common mce4D MCE-FAMILY PROTEIN MCE4D Mb3526c 9 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31792779 Common - hypothetical protein Mb1619c 72 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 31795049 Common esxA 6 KDA EARLY SECRETORY ANTIGENIC TARGET ESAT6 (ESAT-6) Mb3905 5 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31793695 Common - hypothetical protein Mb2543c 6 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794679 Common fdxD PROBABLE FERREDOXIN FDXD Mb3533c 17 COG1141 Fer, Ferredoxin Energy production and conversion 31793077 Common fbpB secreted antigen 85-B fbpB (85B) (antigen 85 complex B) (Mycolyl transferase 85B) (Fibronectin-binding protein B) (Extracellular alpha-antigen) Mb1918c 14 COG0627 COG0627, Predicted esterase General function prediction only 31791351 Common lprK POSSIBLE MCE-FAMILY LIPOPROTEIN LPRK (MCE-FAMILY LIPOPROTEIN MCE1E) Mb0179 9 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31791469 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0298 1 None None None 31792495 Common rfe PUTATIVE UNDECAPAPRENYL-PHOSPHATE ALPHA-N-ACETYLGLUCOSAMINYLTRANSFERASE RFE Mb1334 158 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 31792994 Pathogen - hypothetical protein Mb1834c 1 None None None 31791268 Common - POSSIBLE MEMBRANE PROTEIN Mb0093 11 COG3305 COG3305, Predicted membrane protein Function unknown 31792842 Common argD acetylornithine aminotransferase Mb1683 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 31794683 Pathogen PE_PGRS53 PE-PGRS FAMILY PROTEIN Mb3537 1 None None None 31793387 Common cobS cobalamin synthase Mb2231 103 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 31792167 Common PE_PGRS17 PE-PGRS FAMILY PROTEIN Mb1003c 44 COG3391 COG3391, Uncharacterized conserved protein Function unknown 31792281 Pathogen PE10 PE FAMILY PROTEIN Mb1118 1 None None None 31791261 Common - PROBABLE OXIDOREDUCTASE Mb0086 205 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 31794614 Pathogen - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb3467 1 None None None 31793724 Common - CONSERVED HYPOTHETICAL PROTEIN [SECOND PART] Mb2571 9 None None None 31794764 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb3618c 8 None None None 31791726 Pathogen - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb0558c 1 None None None 31795068 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN [FIRST PART] Mb3924c 155 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 31792347 Common - hypothetical protein Mb1185c 28 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 31791366 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0194 10 None None None 31793267 Pathogen - hypothetical protein Mb2110 1 None None None 31791902 Common rplE 50S ribosomal protein L5 Mb0737 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 31795035 Pathogen - hypothetical protein Mb3891 1 None None None 31792171 Common mprA MYCOBACTERIAL PERSISTENCE REGULATOR MRPA (TWO COMPONENT RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN) Mb1007 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31792727 Common lprI Possible lipoprotein lprI Mb1568c 18 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 31793501 Common uspC PROBABLE PERIPLASMIC SUGAR-BINDING LIPOPROTEIN USPC Mb2345 53 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 31792731 Pathogen - hypothetical protein Mb1572 1 None None None 31794532 Common - PROBABLE TRANSPOSASE Mb3382c 5 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 31791619 Common - hypothetical protein Mb0449c 2 None None None 31791668 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0498 77 COG1279 COG1279, Lysine efflux permease General function prediction only 31794573 Common iunH PROBABLE NUCLEOSIDE HYDROLASE IUNH (PURINE NUCLEOSIDASE) Mb3425 82 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 31794065 Common tsf elongation factor Ts Mb2913c 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 31791608 Common - hypothetical protein Mb0438 16 None None None 31794080 Common rplS 50S ribosomal protein L19 Mb2928c 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 31794717 Common - hypothetical protein Mb3571c 10 None None None 31792603 Common ribG PROBABLE BIFUNCTIONAL riboflavin biosynthesis protein RIBG : Diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino) uracil reductase (HTP reductase) Mb1444 224 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 31791183 Common gyrA DNA gyrase subunit A Mb0006 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 31792525 Common dinG PROBABLE ATP-DEPENDENT HELICASE DING HOMOLOG Mb1364c 125 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 31792162 Common accA2 PROBABLE ACETYL-/PROPIONYL-COENZYME A CARBOXYLASE ALPHA CHAIN (ALPHA SUBUNIT) ACCA2: BIOTIN CARBOXYLASE + BIOTIN CARBOXYL CARRIER PROTEIN (BCCP) Mb0998c 232 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 31792888 Common - hypothetical protein Mb1728c 6 None None None 31794238 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY) Mb3086c 75 COG2186 FadR, Transcriptional regulators Transcription 31794819 Common - PUTATIVE HELICASE Mb3673 107 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 31794873 Common - hypothetical protein Mb3728c 41 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 31791738 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0571 5 None None None 31791880 Common - PROBABLE MEMBRANE SUGAR TRANSFERASE Mb0715 134 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 31794021 Common - CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN Mb2869 10 None None None 31794034 Common - short chain dehydrogenase Mb2882c 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31792123 Common pstS1 PERIPLASMIC PHOSPHATE-BINDING LIPOPROTEIN PSTS1 (PBP-1) (PSTS1) Mb0959 101 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 31792103 Common PPE14 PPE FAMILY PROTEIN Mb0939c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793347 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2191c 15 None None None 31792430 Common sugB PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER SUGB Mb1269 202 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 31792513 Common - POSSIBLE ADENYLATE CYCLASE (ATP PYROPHOSPHATE-LYASE) (ADENYLYL CYCLASE) Mb1352c 57 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31793540 Common amiA2 amidase Mb2384 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 31793733 Pathogen - hypothetical protein Mb2580c 1 None None None 31791499 Common - POSSIBLE CONSERVED EXPORTED PROTEIN Mb0328 4 None None None 31793650 Common - hypothetical protein Mb2496c 95 COG1403 McrA, Restriction endonuclease Defense mechanisms 31792881 Common ppnK inorganic polyphosphate/ATP-NAD kinase Mb1721 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 31791929 Common - hypothetical protein Mb0764c 5 None None None 31794654 Common - HYPOTHETICAL TRANSMEMBRANE PROTEIN [SECOND PART] Mb3508 3 None None None 31793894 Pathogen - hypothetical protein Mb2741 1 None None None 31794457 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3305 13 COG2246 COG2246, Predicted membrane protein Function unknown 31792435 Common - hypothetical protein Mb1274 4 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31793839 Common clpX' POSSIBLE ATP-DEPENDENT PROTEASE ATP-BINDING SUBUNIT CLPX' Mb2686 22 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 31793937 Pathogen - CONSERVED HYPOTHETICAL PROTEIN [FIRST PART] Mb2784c 1 None None None 31792442 Common - POSSIBLE MEMBRANE PROTEIN Mb1281c 8 None None None 31791810 Common - hypothetical protein Mb0644c 25 COG4398 COG4398, Uncharacterized protein conserved in bacteria Function unknown 31794402 Common sigH RNA polymerase sigma factor RpoE Mb3250c 167 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 31792836 Common pheS phenylalanyl-tRNA synthetase subunit alpha Mb1676 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 31794944 Common hisC2 putative aminotransferase Mb3800 240 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 31792414 Common sigE RNA polymerase sigma factor SigE Mb1253 176 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 31792487 Common thrA homoserine dehydrogenase Mb1326 178 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 31794922 Common - POSSIBLE CYTIDINE/DEOXYCYTIDYLATE DEAMINASE Mb3778c 190 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 31791686 Common - hypothetical protein Mb0516c 14 COG2030 MaoC, Acyl dehydratase Lipid metabolism 31792937 Common - POSSIBLE INTEGRAL MEMBRANE PROTEIN Mb1778c 8 None None None 31792802 Common - hypothetical protein Mb1642 12 None None None 31793400 Common glnA1 GLUTAMINE SYNTHETASE GLNA1 (GLUTAMINE SYNTHASE) (GS-I) Mb2244 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 31791626 Common - hypothetical protein Mb0456c 61 COG3496 COG3496, Uncharacterized conserved protein Function unknown 31792929 Common - hypothetical protein Mb1770 6 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 31794133 Common - POSSIBLE GLYCOSYL TRANSFERASE Mb2981 174 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 31791589 Common glnH PROBABLE GLUTAMINE-BINDING LIPOPROTEIN GLNH (GLNBP) Mb0419c 171 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 31794274 Common - HYPOTHETICAL TRANSCRIPTIONAL REGULATORY PROTEIN Mb3122 125 COG1733 COG1733, Predicted transcriptional regulators Transcription 31793855 Common - hypothetical protein Mb2702 3 None None None 31793742 Common - recombination factor protein RarA Mb2589c 234 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 31794461 Common - hypothetical protein Mb3309 2 None None None 31794240 Common fadE22a PROBABLE ACYL-COA DEHYDROGENASE FADE22a [FIRST PART] Mb3088c 35 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31791718 Common galE3 PROBABLE UDP-GLUCOSE 4-EPIMERASE GALE3 (GALACTOWALDENASE) (UDP-GALACTOSE 4-EPIMERASE) (URIDINE DIPHOSPHATE GALACTOSE 4-EPIMERASE) (URIDINE DIPHOSPHO-GALACTOSE 4-EPIMERASE) Mb0550 221 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 31792287 Common desA2 POSSIBLE ACYL-[ACYL-CARRIER PROTEIN] DESATURASE DESA2 (ACYL-[ACP] DESATURASE) (STEAROYL-ACP DESATURASE) Mb1124 8 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 31793930 Common hsdM POSSIBLE TYPE I RESTRICTION/MODIFICATION SYSTEM DNA METHYLASE HSDM (M PROTEIN) (DNA METHYLTRANSFERASE) Mb2777c 160 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 31792455 Common amiB2 amidase Mb1294 217 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 31792810 Common - Probable conserved membrane protein Mb1650c 46 COG3247 HdeD, Uncharacterized conserved protein Function unknown 31793576 Common cysW PROBABLE SULFATE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER CYSW Mb2420c 225 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 31792265 Common fadA3 acetyl-CoA acetyltransferase Mb1103c 187 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31793133 Common - PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE Mb1976 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31793064 Common - hypothetical protein Mb1905 7 None None None 31794868 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb3723c 4 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31792183 Common - hypothetical protein Mb1019c 81 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 31794165 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb3013 99 COG1414 IclR, Transcriptional regulator Transcription 31794468 Common usfY PUTATIVE PROTEIN USFY Mb3316c 1 None None None 31793866 Common - hypothetical protein Mb2713c 11 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 31794396 Common - hypothetical protein Mb3244 10 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 31791793 Pathogen - hypothetical protein Mb0627c 1 None None None 31792702 Common - hypothetical protein Mb1543c 42 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 31792817 Common coaE dephospho-CoA kinase/unknown domain fusion protein Mb1657 200 COG2320 GrpB, Uncharacterized conserved protein Function unknown 31792156 Common - hypothetical protein Mb0992 94 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 31793304 Common metH Probable 5-methyltetrahydrofolate--homocystein methyltransferase MetH (Methionine synthase, vitamin-B12 dependent isozyme) (MS) Mb2148c 175 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 31794712 Common - PROBABLE HYDRATASE Mb3566c 66 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 31792962 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1802c 85 COG1414 IclR, Transcriptional regulator Transcription 31791275 Common - POSSIBLE OXIDOREDUCTASE Mb0100 40 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 31792554 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1393 64 COG3903 COG3903, Predicted ATPase General function prediction only 31791637 Common - PROBABLE ALDEHYDE DEHYDROGENASE Mb0467 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 31792825 Common - hypothetical protein Mb1665c 3 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 31794746 Common bphD 2-HYDROXY-6-OXO-6-PHENYLHEXA-2,4-DIENOATE HYDROLASE BPHD Mb3600c 172 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31792180 Common grcC2 PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC2 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) Mb1016c 228 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 31791946 Common phoR POSSIBLE TWO COMPONENT SYSTEM RESPONSE SENSOR KINASE MEMBRANE ASSOCIATED PHOR Mb0781 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 31791951 Common - POSSIBLE FERREDOXIN Mb0786c 5 COG1141 Fer, Ferredoxin Energy production and conversion 31794895 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3750 1 None None None 31794742 Common nat ARYLAMINE N-ACETYLTRANSFERASE NAT (ARYLAMINE ACETYLASE) Mb3596c 44 COG2162 NhoA, Arylamine N-acetyltransferase Secondary metabolites biosynthesis, transport, and catabolism 31794248 Common ccrB camphor resistance protein CrcB Mb3096 8 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 31791481 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR/ACRR-FAMILY) Mb0310 92 COG1309 AcrR, Transcriptional regulator Transcription 31793051 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb1892 5 COG2261 COG2261, Predicted membrane protein Function unknown 31793333 Common murG N-acetylglucosaminyl transferase Mb2177c 201 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 31792397 Common - hypothetical protein Mb1236c 6 COG3899 COG3899, Predicted ATPase General function prediction only 31793161 Common - hypothetical protein Mb2004c 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 31792366 Pathogen PE12 PE FAMILY PROTEIN Mb1205c 1 None None None 31791488 Common - POSSIBLE CONSERVED EXPORTED PROTEIN Mb0317 25 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 31794803 Common - hypothetical protein Mb3657 18 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 31793449 Pathogen lppN Probable lipoprotein lppN Mb2293 2 None None None 31791751 Common - hypothetical protein Mb0584 7 None None None 31791770 Common yrbE2B CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE2B Mb0603 72 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 31792015 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0850c 156 COG0640 ArsR, Predicted transcriptional regulators Transcription 31793993 Common - hypothetical protein Mb2841c 99 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 31792533 Common - PROBABLE INTEGRAL MEMBRANE PROTEIN Mb1372 29 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 31791920 Common mapA methionine aminopeptidase Mb0755 236 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 31792392 Common - POSSIBLE TRANSPOSASE Mb1231c 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 31795022 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3878 65 COG2119 COG2119, Predicted membrane protein Function unknown 31791201 Common - PUTATIVE SECRETED PROTEIN P60-RELATED PROTEIN [FIRST PART] Mb0024 1 None None None 31792985 Common - hypothetical protein Mb1825 3 None None None 31792903 Common fadB3b PROBABLE 3-HYDROXYBUTYRYL-COA DEHYDROGENASE FADB3b [SECOND PART] (BETA-HYDROXYBUTYRYL-COA DEHYDROGENASE) (BHBD) Mb1743 73 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 31794487 Common deoD purine nucleoside phosphorylase Mb3335 133 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 31795058 Common - PUTATIVE CBXX/CFQX FAMILY PROTEIN Mb3914c 51 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 31791310 Common fadE1 PROBABLE ACYL-CoA DEHYDROGENASE FADE1 Mb0136c 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31791977 Common purQ phosphoribosylformylglycinamidine synthase subunit I Mb0812 228 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 31791818 Common rpmG 50S ribosomal protein L33 Mb0653 83 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 31793659 Common - hypothetical protein Mb2505c 19 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 31792796 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb1636 1 None None None 31792570 Common - hypothetical protein Mb1411 25 COG3482 COG3482, Uncharacterized conserved protein Function unknown 31791693 Common hemD PROBABLE UROPORPHYRIN-III C-METHYLTRANSFERASE HEMD (UROPORPHYRINOGEN III METHYLASE) (UROGEN III METHYLASE) (SUMT) (UROGEN III METHYLASE) (UROM) Mb0524 182 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 31793409 Common - hypothetical protein Mb2253c 74 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 31794548 Common - hypothetical protein Mb3400c 30 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 31791958 Common - PROBABLE DEHYDROGENASE/REDUCTASE Mb0793 121 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 31793151 Common - hypothetical protein Mb1994c 31 COG3668 ParE, Plasmid stabilization system protein General function prediction only 31792546 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Mb1385 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31791890 Common rpsS 30S ribosomal protein S19 Mb0725 240 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 31794408 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase Mb3256 225 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 31792038 Common - PUTATIVE TRANSPOSASE (FRAGMENT) Mb0873 2 None None None 31794264 Common - PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE Mb3112 236 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 31792679 Common inhA enoyl-(acyl carrier protein) reductase Mb1520 187 COG0623 FabI, Enoyl- acyl-carrier-protein 31791662 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase Mb0492 199 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 31793885 Common sthA soluble pyridine nucleotide transhydrogenase Mb2732 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 31793486 Common - hypothetical protein Mb2330c 72 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 31793234 Common ppm1 Polyprenol-monophosphomannose synthase Ppm1 Mb2077c 208 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 31792255 Common lpqV PUTATIVE LIPOPROTEIN LPQV Mb1093c 1 None None None 31794436 Common - hypothetical protein Mb3284c 8 None None None 31793587 Pathogen PE24 POSSIBLE PE FAMILY-RELATED PROTEIN Mb2431 1 None None None 31794011 Common ugpAb PROBABLE Sn-GLYCEROL-3-PHOSPHATE TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER UGPAB [SECOND PART] Mb2859c 139 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 31792672 Common - HYPOTHETICAL INVASION PROTEIN Mb1513 104 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 31794733 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb3587c 63 COG1309 AcrR, Transcriptional regulator Transcription 31793562 Common mbtJ PUTATIVE ACETYL HYDROLASE MBTJ Mb2406 97 COG0657 Aes, Esterase/lipase Lipid metabolism 31792073 Common - hypothetical protein Mb0909 7 None None None 31793366 Common fadD15 Probable long-chain-fatty-acid-CoA ligase fadD15 (FATTY-ACID-CoA SYNTHETASE) (FATTY-ACID-CoA SYNTHASE) Mb2210 218 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 31791486 Common - hypothetical protein Mb0315c 1 None None None 31792372 Common - N-succinyldiaminopimelate aminotransferase Mb1211 223 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 31794096 Common amt PROBABLE AMMONIUM-TRANSPORT INTEGRAL MEMBRANE PROTEIN AMT Mb2944c 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 31794629 Common cut4 PROBABLE CUTINASE PRECURSOR CUT4 Mb3482 3 None None None 31794160 Common ppk polyphosphate kinase Mb3008 162 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 31794936 Common - hypothetical protein Mb3792 4 None None None 31793149 Pathogen - hypothetical protein Mb1992 1 None None None 31793058 Pathogen - hypothetical protein Mb1899 1 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 31795032 Common gltD glutamate synthase subunit beta Mb3888c 198 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 31795007 Common - TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ARAC-FAMILY) Mb3863 104 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 31793891 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb2738c 1 None None None 31794478 Common lpqC POSSIBLE ESTERASE LIPOPROTEIN LPQC Mb3326c 29 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 31794417 Common - hypothetical protein Mb3265c 29 COG0490 COG0490, Putative regulatory, ligand-binding protein related to C-terminal domains of K+ channels Inorganic ion transport and metabolism 31794174 Pathogen - hypothetical protein Mb3022 1 None None None 31793884 Common - hypothetical protein Mb2731c 8 None None None 31792302 Common - hypothetical protein Mb1139c 4 None None None 31794489 Common upp uracil phosphoribosyltransferase Mb3337c 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 31792238 Common - IS1081 transposase Mb1076 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 31794419 Common - PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN Mb3267c 189 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 31794302 Common - hypothetical protein Mb3150 15 None None None 31793395 Common - hypothetical protein Mb2239 111 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 31791649 Common pcaA MYCOLIC ACID SYNTHASE PCAA (CYCLOPROPANE SYNTHASE) Mb0479c 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 31791972 Common - CONSERVED HYPOTHETICAL PROTEIN [FIRST PART] Mb0807 27 COG3573 COG3573, Predicted oxidoreductase General function prediction only 31794258 Common - hypothetical protein Mb3106c 61 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31792337 Common echA10 enoyl-CoA hydratase Mb1174c 157 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31795024 Common - hypothetical protein Mb3880 5 None None None 31794859 Common - hypothetical protein Mb3713c 150 COG1610 COG1610, Uncharacterized conserved protein Function unknown 31794276 Common PE_PGRS63 PE-PGRS FAMILY PROTEIN, PROBABLY TRIACYLGLYCEROL LIPASE (ESTERASE/LIPASE) (TRIGLYCERIDE LIPASE) (TRIBUTYRASE) Mb3124c 72 COG0657 Aes, Esterase/lipase Lipid metabolism 31794397 Common whiB1 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB1 Mb3245 19 None None None 31793451 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb2295 7 COG2149 COG2149, Predicted membrane protein Function unknown 31793740 Common - hypothetical protein Mb2587 3 None None None 31792098 Common - hypothetical protein Mb0934 5 COG3427 COG3427, Uncharacterized conserved protein Function unknown 31793248 Common cobH precorrin-8X methylmutase Mb2091 101 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 31794285 Common fprA PROBABLE NADPH:ADRENODOXIN OXIDOREDUCTASE FPRA (NADPH-FERREDOXIN REDUCTASE) Mb3133 115 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 31794005 Common - hypothetical protein Mb2853c 20 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 31793038 Common ureA urease subunit gamma Mb1879 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 31794921 Common - PUTATIVE INTEGRASE (FRAGMENT) Mb3777 4 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 31791998 Common - hypothetical protein Mb0833c 15 None None None 31793611 Common PE25 PE FAMILY PROTEIN Mb2457c 1 None None None 31792207 Common lpqT PUTATIVE CONSERVED LIPOPROTEIN LPQT Mb1044c 1 None None None 31793669 Pathogen PE_PGRS43b PE-PGRS FAMILY PROTEIN [SECOND PART] Mb2517c 1 None None None 31791908 Common rpmD 50S ribosomal protein L30 Mb0743 91 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 31793427 Common accD6 ACETYL/PROPIONYL-CoA CARBOXYLASE (BETA SUBUNIT) ACCD6 Mb2271 173 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 31794515 Common dacB1 PROBABLE PENICILLIN-BINDING PROTEIN DACB1 (D-ALANYL-D-ALANINE CARBOXYPEPTIDASE) (DD-PEPTIDASE) (DD-CARBOXYPEPTIDASE) (PBP) (DD-TRANSPEPTIDASE) (SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE) Mb3363 152 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 31791776 Common mce2F MCE-FAMILY PROTEIN MCE2F Mb0610 11 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31791895 Common rpsQ 30S ribosomal protein S17 Mb0730 226 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 31794564 Common - hypothetical protein Mb3416c 2 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794756 Common - PUTATIVE TRNA/RRNA METHYLTRANSFERASE Mb3610c 208 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 31793791 Common - pyridoxine biosynthesis protein Mb2638c 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 31794125 Common - hypothetical protein Mb2973c 8 COG3161 UbiC, 4-hydroxybenzoate synthetase (chorismate lyase) Coenzyme metabolism 31794227 Common - PROBABLE MONOOXYGENASE Mb3075c 79 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 31792036 Common cysK2 POSSIBLE CYSTEINE SYNTHASE A CYSK2 (O-ACETYLSERINE SULFHYDRYLASE) (O-ACETYLSERINE (THIOL)-LYASE) (CSASE) Mb0871 214 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 31793657 Common gdh PROBABLE NAD-DEPENDENT GLUTAMATE DEHYDROGENASE GDH (NAD-GDH) (NAD-DEPENDENT GLUTAMIC DEHYDROGENASE) Mb2503c 76 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 31793301 Common hisG ATP phosphoribosyltransferase Mb2145c 212 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 31791592 Common thiE thiamine-phosphate pyrophosphorylase Mb0422c 184 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 31791574 Pathogen - POSSIBLE SECRETED PROTEIN Mb0404c 1 None None None 31794912 Common - POSSIBLE OXIDOREDUCTASE Mb3768c 31 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 31791695 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb0526 4 None None None 31792054 Common moaE2 PUTATIVE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN E2 MOAE2 (MOLYBDOPTERIN CONVERTING FACTOR LARGE SUBUNIT) (MOLYBDOPTERIN [MPT] CONVERTING FACTOR, SUBUNIT 2) Mb0890 68 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 31791458 Pathogen PE_PGRS4 PE-PGRS FAMILY PROTEIN Mb0287c 1 None None None 31792133 Common - POSSIBLE FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (FAPY-DNA GLYCOSYLASE) Mb0969 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 31792682 Common - hypothetical protein Mb1523 13 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 31791413 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0241c 9 None None None 31791723 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0555c 5 COG5283 COG5283, Phage-related tail protein Function unknown 31793567 Common - hypothetical protein Mb2411c 5 None None None 31791948 Common - hypothetical protein Mb0783c 5 None None None 31794988 Common - PUTATIVE ACYLTRANSFERASE Mb3844c 120 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 31792384 Common - hypothetical protein Mb1223 55 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31791459 Common PPE3 PPE FAMILY PROTEIN Mb0288 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793758 Common - POSSIBLE CONSERVED MEMBRANE GLYCINE RICH PROTEIN Mb2605 83 COG2321 COG2321, Predicted metalloprotease General function prediction only 31792942 Common - hypothetical protein Mb1783c 8 None None None 31793647 Common - hypothetical protein Mb2493c 16 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31792600 Common fmt methionyl-tRNA formyltransferase Mb1441 214 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 31791375 Common - POSSIBLE OXIDOREDUCTASE Mb0203 178 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 31793017 Common cfp17 CONSERVED HYPOTHETICAL PROTEIN CFP17 Mb1858 65 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 31792879 Pathogen - hypothetical protein Mb1719 1 None None None 31791190 Common trpG para-aminobenzoate synthase component II Mb0013 236 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 31792481 Common - hypothetical protein Mb1320 3 None None None 31793972 Common lppV PROBABLE CONSERVED LIPOPROTEIN LPPV Mb2819c 3 COG4717 COG4717, Uncharacterized conserved protein Function unknown 31792087 Common ompA PROBABLE OUTER MEMBRANE PROTEIN A OMPA Mb0923 163 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 31792112 Common mntH putative manganese transport protein MntH Mb0948c 117 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 31791296 Common oxcA putative oxalyl-CoA decarboxylase Mb0122c 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 31793876 Common - hypothetical protein Mb2723 133 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 31794620 Common rplM 50S ribosomal protein L13 Mb3473c 229 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 31791445 Common narU PUTATIVE INTEGRAL MEMBRANE NITRITE EXTRUSION PROTEIN NARU (NITRITE FACILITATOR) Mb0273 73 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 31793274 Common - Probable membrane protein Mb2118c 4 None None None 31794365 Common - PROBABLE TRANSPOSASE Mb3213c 63 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 31794844 Common nth PROBABLE ENDONUCLEASE III NTH (DNA-(APURINIC OR APYRIMIDINIC SITE)LYASE) (AP LYASE) (AP ENDONUCLEASE CLASS I) (ENDODEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC)) (DEOXYRIBONUCLEASE (APURINIC OR APYRIMIDINIC)) Mb3698c 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 31795079 Common - hypothetical protein Mb3936c 1 None None None 31792908 Common - hypothetical protein Mb1749c 6 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31793392 Common pepB leucyl aminopeptidase Mb2236 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 31792078 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LUXR-FAMILY) Mb0914c 104 COG3903 COG3903, Predicted ATPase General function prediction only 31794480 Common - hypothetical protein Mb3328c 212 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 31791208 Pathogen - PUTATIVE REMNANT OF A TRANSPOSASE Mb0032 1 None None None 31792010 Common - hypothetical protein Mb0845c 58 COG1316 LytR, Transcriptional regulator Transcription 31793802 Common - hypothetical protein Mb2649 15 COG4762 COG4762, Uncharacterized protein conserved in bacteria Function unknown 31792201 Common ksgA dimethyladenosine transferase Mb1037 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 31794251 Common - hypothetical protein Mb3099c 27 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31793262 Common - hypothetical protein Mb2105 9 None None None 31794293 Common - hypothetical protein Mb3141 73 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 31792153 Pathogen - hypothetical protein Mb0989c 1 None None None 31794662 Common - hypothetical protein Mb3516 8 COG2259 COG2259, Predicted membrane protein Function unknown 31793927 Common dapA dihydrodipicolinate synthase Mb2774c 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 31791259 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0084 21 COG0640 ArsR, Predicted transcriptional regulators Transcription 31792891 Common PPE22 PPE FAMILY PROTEIN Mb1731c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794142 Common - POSSIBLE METHYLTRANSFERASE (METHYLASE) Mb2990c 205 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 31793684 Common scoA PROBABLE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE (ALPHA SUBUNIT) SCOA (3-OXO ACID:CoA TRANSFERASE) (OXCT A) (SUCCINYL-COA:3-OXOACID-COENZYME A TRANSFERASE) Mb2532c 105 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 31791507 Common - hypothetical protein Mb0336c 34 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31791806 Common - hypothetical protein Mb0640 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 31794072 Common - hypothetical protein Mb2920c 207 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 31791886 Common rplC 50S ribosomal protein L3 Mb0721 240 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 31793131 Common - PROBABLE OXIDOREDUCTASE Mb1974 75 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 31795055 Common - CONSERVED HYPOTHETICAL ALANINE AND GLYCINE RICH PROTEIN Mb3911c 1 None None None 31793768 Common apt adenine phosphoribosyltransferase Mb2615c 165 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 31792531 Common - 9.5 KDA CULTURE FILTRATE ANTIGEN CFP10A Mb1370 40 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 31792556 Common - PROBABLE OXIDOREDUCTASE Mb1395 36 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31793456 Common - Possible glycerolphosphodiesterase Mb2300c 65 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 31791716 Common menA 1,4-dihydroxy-2-naphthoate octaprenyltransferase Mb0548c 91 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 31792476 Common - hypothetical protein Mb1315 46 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 31792579 Common pyrF orotidine 5'-phosphate decarboxylase Mb1420 62 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 31791784 Common tcrA PUTATIVE TWO COMPONENT DNA BINDING TRANSCRIPTIONAL REGULATORY PROTEIN TCRA Mb0618c 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31793749 Common - LONG CONSERVED HYPOTHETICAL PROTEIN [SECOND PART] Mb2596 36 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 31792008 Common phoT PROBABLE PHOSPHATE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER PHOT Mb0843 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 31794495 Common deoA thymidine phosphorylase Mb3343c 118 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 31794609 Common gadB PROBABLE GLUTAMATE DECARBOXYLASE GADB Mb3462c 70 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 31793666 Pathogen PE_PGRS42a PE-PGRS FAMILY PROTEIN [FIRST PART] Mb2514c 1 None None None 31791307 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0133 15 COG3619 COG3619, Predicted membrane protein Function unknown 31792594 Common lipI PROBABLE LIPASE LIPH Mb1435c 137 COG0657 Aes, Esterase/lipase Lipid metabolism 31792091 Common prrA TWO COMPONENT RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN PRRA Mb0927c 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31792949 Pathogen wag22a PE-PGRS FAMILY PROTEIN WAG22A [FIRST PART] Mb1790c 1 None None None 31793105 Common fadB5 POSSIBLE OXIDOREDUCTASE FADB5 Mb1947c 160 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 31791991 Common purL phosphoribosylformylglycinamidine synthase II Mb0826 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 31793167 Common - PROBABLE METHYLTRANSFERASE Mb2010 160 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 31792354 Common mutT2 PROBABLE MUTATOR PROTEIN MUTT2 (7,8-dihydro-8-oxoguanine-triphosphatase) (8-OXO-DGTPASE) Mb1192 10 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 31794138 Common - POSSIBLE GLYCOSYL TRANSFERASE Mb2986c 35 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 31794360 Common - hypothetical protein Mb3208 21 COG4683 COG4683, Uncharacterized protein conserved in bacteria Function unknown 31793075 Common rpfC PROBABLE RESUSCITATION-PROMOTING FACTOR RPFC Mb1916c 12 None None None 31791828 Common mmaA2 METHOXY MYCOLIC ACID SYNTHASE 2 MMAA2 (METHYL MYCOLIC ACID SYNTHASE 2) (MMA2) (HYDROXY MYCOLIC ACID SYNTHASE) Mb0663c 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 31794798 Common ppa inorganic pyrophosphatase Mb3652 187 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 31793812 Common - hypothetical protein Mb2659c 153 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 31794047 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mb2895c 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 31794959 Common - hypothetical protein Mb3815c 92 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 31794153 Common thiL thiamine monophosphate kinase Mb3001c 183 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 31792047 Common fadA acetyl-CoA acetyltransferase Mb0882 173 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31792424 Common - PROBABLE MEMBRANE PROTEIN Mb1263c 44 COG4420 COG4420, Predicted membrane protein Function unknown 31792345 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1183 117 COG1725 COG1725, Predicted transcriptional regulators Transcription 31792146 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Mb0982 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 31793100 Common - hypothetical protein Mb1942c 3 None None None 31794884 Common - POSSIBLE LIGASE Mb3739 43 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 31791650 Common - hypothetical protein Mb0480c 2 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 31793250 Common - hypothetical protein Mb2093c 32 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 31793127 Common echA13 enoyl-CoA hydratase Mb1970c 175 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31792811 Common cya MEMBRANE-ANCHORED ADENYLYL CYCLASE CYA (ATP PYROPHOSPHATE-LYASE) (ADENYLATE CYCLASE) Mb1651c 82 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31792899 Common cmk cytidylate kinase Mb1739 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 31794196 Pathogen PE27A PE family protein Mb3044c 1 None None None 31793286 Common - hypothetical protein Mb2130c 2 None None None 31793949 Pathogen - hypothetical protein Mb2796c 1 None None None 31793320 Common TB18.6 hypothetical protein Mb2164c 119 COG1881 COG1881, Phospholipid-binding protein General function prediction only 31791393 Common fadE3 PROBABLE ACYL-COA DEHYDROGENASE FADE3 Mb0221c 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31792625 Common - hypothetical protein Mb1466 5 None None None 31793785 Common speE spermidine synthase Mb2632 110 COG4262 COG4262, Predicted spermidine synthase with an N-terminal membrane domain General function prediction only 31792283 Common celA2b PROBABLE CELLULASE CELA2B (ENDO-1,4-BETA-GLUCANASE) (ENDOGLUCANASE) (CARBOXYMETHYL CELLULASE) Mb1120 7 None None None 31793726 Pathogen lprR PROBABLE CONSERVED LIPOPROTEIN LPRR Mb2573 1 None None None 31791936 Pathogen - hypothetical protein Mb0771c 1 None None None 31791868 Common fusA1 elongation factor G Mb0703 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 31791964 Common - hypothetical protein Mb0799c 14 COG4328 COG4328, Uncharacterized protein conserved in bacteria Function unknown 31791390 Common nadR POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN NADR (PROBABLY ASNC-FAMILY) Mb0218c 34 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 31792851 Common pks9 Probable polyketide synthase pks9 Mb1692 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31793470 Common sseB Probable thiosulfate sulfurtransferase SseB Mb2314 143 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 31794695 Common - hypothetical protein Mb3549 6 None None None 31794212 Common - POSSIBLE TRANSFERASE Mb3060c 129 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 31793097 Common - hypothetical protein Mb1939 2 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 31791557 Common - POSSIBLE RNA METHYLTRANSFERASE (RNA METHYLASE) Mb0387c 66 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 31791858 Common - hypothetical protein Mb0693 29 COG3327 PaaX, Phenylacetic acid-responsive transcriptional repressor Transcription 31794823 Pathogen PE_PGRS61 PE-PGRS FAMILY-RELATED PROTEIN Mb3677 1 None None None 31791874 Common - hypothetical protein Mb0709c 24 COG4427 COG4427, Uncharacterized protein conserved in bacteria Function unknown 31793440 Common - hypothetical protein Mb2284 210 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 31791387 Common - hypothetical protein Mb0215 1 COG1159 Era, GTPase General function prediction only 31793966 Common ltp1 lipid-transfer protein Mb2813c 178 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31793918 Common 35kd_ag CONSERVED 35 KDA ALANINE RICH PROTEIN Mb2765c 12 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 31792956 Common - hypothetical protein Mb1796 18 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 31792859 Common - hypothetical protein Mb1700c 67 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 31791766 Common - POSSIBLE CONSERVED EXPORTED PROTEIN Mb0599 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 31791492 Common - hypothetical protein Mb0321 3 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 31792803 Common pykA pyruvate kinase Mb1643 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 31792463 Common - CONSERVED HYPOTHETICAL SECRETED PROTEIN Mb1302c 2 None None None 31791542 Common - hypothetical protein Mb0372c 8 COG4833 COG4833, Predicted glycosyl hydrolase Carbohydrate transport and metabolism 31792312 Common - hypothetical protein Mb1149c 5 None None None 31793912 Common - POSSIBLE ALANINE RICH TRANSFERASE Mb2759c 10 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 31791347 Common mce1A MCE-FAMILY PROTEIN MCE1A Mb0175 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31795004 Common - TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb3860c 35 COG1309 AcrR, Transcriptional regulator Transcription 31792769 Common - Probable phiRv1 phage protein Mb1609c 2 None None None 31791197 Common TB39.8 hypothetical protein Mb0020c 37 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 31792528 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1367 8 None None None 31793527 Common - hypothetical protein Mb2371 5 None None None 31792258 Pathogen PE_PGRS19 PE-PGRS FAMILY PROTEIN Mb1096c 1 None None None 31793987 Common - PUTATIVE TRANSPOSASE [FIRST PART] Mb2835 10 None None None 31791671 Common regX3 TWO COMPONENT SENSORY TRANSDUCTION PROTEIN REGX3 (TRANSCRIPTIONAL REGULATORY PROTEIN) (PROBABLY LUXR-FAMILY) Mb0501 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31793617 Common - hypothetical protein Mb2463 37 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 31792295 Common - hypothetical protein Mb1132c 4 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 31794348 Common hpx POSSIBLE NON-HEME HALOPEROXIDASE HPX Mb3196c 127 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31793827 Common cadI CADMIUM INDUCIBLE PROTEIN CADI Mb2674 26 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 31793820 Pathogen PE_PGRS46 PE-PGRS FAMILY PROTEIN Mb2667c 1 None None None 31792005 Common - PROBABLE CONSERVED EXPORTED PROTEIN Mb0840c 4 None None None 31791327 Common - PUTATIVE QUINONE OXIDOREDUCTASE (NADPH:QUINONE OXIDOREDUCTASE) (ZETA-CRYSTALLIN) Mb0154 168 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 31793351 Common idsA2 PROBABLE GERANYLGERANYL PYROPHOSPHATE SYNTHETASE IDSA2 (GGPPSASE) (GGPP SYNTHETASE) (GERANYLGERANYL DIPHOSPHATE SYNTHASE) Mb2195 228 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 31793775 Pathogen PE_PGRS44 PE-PGRS FAMILY PROTEIN Mb2622 1 None None None 31793204 Pathogen - hypothetical protein Mb2047c 1 None None None 31794860 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3714 10 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 31794833 Common dppD PROBABLE DIPEPTIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER DPPD Mb3687c 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 31793150 Pathogen - hypothetical protein Mb1993c 1 None None None 31794500 Common sdhB succinate dehydrogenase iron-sulfur subunit Mb3348 206 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 31792783 Common - hypothetical protein Mb1623 15 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31794225 Pathogen - hypothetical protein Mb3073c 1 None None None 31794103 Common - hypothetical protein Mb2951c 36 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 31792718 Common - hypothetical protein Mb1559c 17 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 31794522 Common - hypothetical protein Mb3370 69 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31793798 Common - hypothetical protein Mb2645c 109 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 31791987 Common - hypothetical protein Mb0822c 51 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 31791470 Common - PROBABLE PROTEASE PRECURSOR Mb0299 103 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 31792319 Common - hypothetical protein Mb1156 2 None None None 31794115 Common drrC PROBABLE DAUNORUBICIN-DIM-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DRRC Mb2963 48 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 31794008 Common ugpC PROBABLE Sn-GLYCEROL-3-PHOSPHATE TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER UGPC Mb2856c 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 31794598 Common groEL chaperonin GroEL Mb3451c 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 31793660 Pathogen - hypothetical protein Mb2506c 1 None None None 31792221 Common kdpA potassium-transporting ATPase subunit A Mb1058 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 31794170 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb3018 30 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 31793116 Pathogen - hypothetical protein Mb1959c 1 None None None 31793052 Common adhA Probable alcohol dehydrogenase adhA Mb1893 174 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 31792198 Common metG methionyl-tRNA synthetase Mb1034c 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31793316 Common uppP undecaprenyl pyrophosphate phosphatase Mb2160c 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 31793363 Common TB16.3 hypothetical protein Mb2207c 9 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 31794423 Common - hypothetical protein Mb3271c 2 None None None 31794605 Pathogen - hypothetical protein Mb3458c 1 None None None 31793601 Pathogen - hypothetical protein Mb2445 1 None None None 31793477 Common htpG heat shock protein 90 Mb2321c 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 31791743 Common - POSSIBLE OXIDOREDUCTASE Mb0576c 85 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 31791525 Pathogen - PROBABLE CONSERVED MEMBRANE PROTEIN Mb0355 2 None None None 31792212 Common - nucleoside triphosphate pyrophosphohydrolase Mb1049 146 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 31792696 Pathogen - hypothetical protein Mb1537 1 None None None 31792641 Common zwf2 glucose-6-phosphate 1-dehydrogenase Mb1482c 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 31793718 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2565 3 None None None 31793904 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2751c 5 None None None 31794026 Common cobO cob(I)yrinic acid a,c-diamide adenosyltransferase Mb2874c 141 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 31794762 Common radA DNA repair protein RadA Mb3616 215 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 31792026 Common lpqR PROBABLE CONSERVED LIPOPROTEIN LPQR Mb0861 45 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 31793819 Common - hypothetical protein Mb2666c 6 None None None 31791700 Common - POSSIBLE EXPORTED PROTEIN Mb0531 4 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 31791511 Common - hypothetical protein Mb0340 2 None None None 31792247 Common - hypothetical protein Mb1085 44 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 31793443 Common - conserved hypothetical proline rich protein Mb2287c 160 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 31792226 Common - PROBABLE TRANSPOSASE (FRAGMENT) Mb1063c 9 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 31791673 Pathogen - hypothetical protein Mb0503c 1 None None None 31793276 Common tatC Probable Sec-independent protein translocase transmembrane protein tatC Mb2120c 197 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 31792860 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1701c 128 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 31794077 Common - hypothetical protein Mb2925c 17 None None None 31792011 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0846c 206 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 31794901 Common - POSSIBLE TRANSFERASE Mb3756 148 COG1964 COG1964, Predicted Fe-S oxidoreductases General function prediction only 31794918 Pathogen - hypothetical protein Mb3774 1 None None None 31794817 Common - hypothetical protein Mb3671c 4 None None None 31792340 Common mmpL13 PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL13 Mb1177 47 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31793015 Common - hypothetical protein Mb1856 23 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 31792992 Pathogen PE_PGRS32a PE-PGRS FAMILY PROTEIN [FIRST PART] Mb1832c 1 None None None 31792465 Common - PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER Mb1304c 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 31794776 Common - pantothenate kinase Mb3630c 100 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 31792924 Common narX Probable nitrate reductase NarX Mb1765c 66 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 31791214 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0038c 15 None None None 31793219 Common - hypothetical protein Mb2062 11 None None None 31794463 Common sseA PROBABLE THIOSULFATE SULFURTRANSFERASE SSEA (RHODANESE) (THIOSULFATE CYANIDE TRANSSULFURASE) (THIOSULFATE THIOTRANSFERASE) Mb3311 144 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 31791479 Common - hypothetical protein Mb0308 1 None None None 31792173 Common - PROBABLE SERINE PROTEASE (SERINE PROTEINASE) Mb1009 220 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 31792043 Common far PROBABLE FATTY-ACID-COA RACEMASE FAR Mb0878 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 31792730 Common - Possible ketoacyl reductase Mb1571 233 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 31794626 Common - PROBABLE SECRETED SERINE PROTEASE Mb3479 112 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 31794961 Common - nucleoside diphosphate kinase regulator Mb3817 7 COG0782 GreA, Transcription elongation factor Transcription 31791254 Common - PROBABLE OXIDOREDUCTASE Mb0079c 97 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31791266 Common - hypothetical protein Mb0091 7 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 31794517 Common nagA PROBABLE N-ACETYLGLUCOSAMINE-6-PHOSPHATE DEACETYLASE NAGA (GLCNAC 6-P DEACETYLASE) Mb3365 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 31791979 Common - hypothetical protein Mb0814c 10 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 31792593 Common lipH PROBABLE LIPASE LIPH Mb1434c 141 COG0657 Aes, Esterase/lipase Lipid metabolism 31793339 Common - hypothetical protein Mb2183c 4 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 31792809 Common cydA Probable integral membrane cytochrome D ubiquinol oxidase (subunit I) cydA (Cytochrome BD-I oxidase subunit I) Mb1649c 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 31793101 Common katG CATALASE-PEROXIDASE-PEROXYNITRITASE T KATG Mb1943c 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 31793415 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2259 28 COG3346 COG3346, Uncharacterized conserved protein Function unknown 31794591 Common guaB3 inositol-5-monophosphate dehydrogenase Mb3444c 218 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 31792105 Common betP POSSIBLE GLYCINE BETAINE TRANSPORT INTEGRAL MEMBRANE PROTEIN BETP Mb0941 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 31791539 Common mgtE POSSIBLE Mg2+ TRANSPORT TRANSMEMBRANE PROTEIN MGTE Mb0369 171 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 31793071 Common cyp140 Probable cytochrome p450 140 CYP140 Mb1912c 82 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31795047 Common PPE68 PPE FAMILY PROTEIN Mb3903 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793020 Common - hypothetical protein Mb1861 23 COG0789 SoxR, Predicted transcriptional regulators Transcription 31794865 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb3719c 27 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 31794156 Common - POSSIBLE CONSERVED SECRETED PROTEIN Mb3004 6 None None None 31792541 Common fadD33 acyl-CoA synthetase Mb1380 212 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31791460 Common - hypothetical protein Mb0289 22 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31794546 Common - hypothetical protein Mb3398c 9 None None None 31795062 Pathogen - hypothetical protein Mb3918c 1 None None None 31794406 Common - POSSIBLE TRANSFERASE Mb3254c 25 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 31792721 Pathogen - hypothetical protein Mb1562 1 None None None 31793048 Common modB PROBABLE MOLBDENUM-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER MODB Mb1889 178 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 31793211 Common pfkB Probable phosphofructokinase pfkB (PHOSPHOHEXOKINASE) Mb2054c 112 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 31795094 Common - putative inner membrane protein translocase component YidC Mb3952c 209 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 31791178 Common dnaA chromosomal replication initiation protein Mb0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 31792627 Common - POSSIBLE CONSERVED EXPORTED PROTEIN Mb1468 18 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 31794210 Common - POSSIBLE TRANSFERASE Mb3058 215 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 31794875 Common gshA GLUTAMATE--CYSTEINE LIGASE GSHA (GAMMA-GLUTAMYLCYSTEINE SYNTHETASE) (GAMMA-ECS) (GCS) (GAMMA-GLUTAMYL-L-CYSTEINE SYNTHETASE) Mb3730c 54 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 31791919 Common adk adenylate kinase Mb0754 230 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 31794110 Common ppsC PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSC Mb2958 228 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794810 Common - PUTATIVE TRANSPOSASE Mb3664c 87 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 31792720 Common - Probable transcriptional regulator Mb1561 144 COG1309 AcrR, Transcriptional regulator Transcription 31792412 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1251c 15 COG1309 AcrR, Transcriptional regulator Transcription 31793542 Common - hypothetical protein Mb2386c 1 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 31795013 Common - hypothetical protein Mb3869 7 None None None 31793887 Common - POSSIBLE HYDROLASE Mb2734 197 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31794638 Common infA translation initiation factor IF-1 Mb3491c 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 31792076 Common - PROBABLE EXPORTED PROTEIN Mb0912 5 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 31793118 Common mpt63 IMMUNOGENIC PROTEIN MPT63 (ANTIGEN MPT63/MPB63) (16 KD IMMUNOPROTECTIVE EXTRACELLULAR PROTEIN) Mb1961c 1 None None None 31794570 Common lpqD PROBABLE CONSERVED LIPOPROTEIN LPQD Mb3422 19 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 31792515 Common - POSSIBLE ADENYLATE CYCLASE (ATP PYROPHOSPHATE-LYASE) (ADENYLYL CYCLASE) Mb1354c 61 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31793571 Common ggtB PROBABLE GAMMA-GLUTAMYLTRANSPEPTIDASE PRECURSOR GGTB (GAMMA-GLUTAMYLTRANSFERASE) (GLUTAMYL TRANSPEPTIDASE) Mb2415 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 31794476 Common lhr PROBABLE ATP-DEPENDENT HELICASE LHR (LARGE HELICASE-RELATED PROTEIN) Mb3324 159 COG1201 Lhr, Lhr-like helicases General function prediction only 31793863 Common ceoB TRK SYSTEM POTASSIUM UPTAKE PROTEIN CEOB Mb2710 104 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 31793962 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase Mb2809c 206 COG0196 RibF, FAD synthase Coenzyme metabolism 31793498 Common - hypothetical protein Mb2342c 163 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 31794088 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb2936c 30 COG1309 AcrR, Transcriptional regulator Transcription 31793381 Common cbhK Probable carbohydrate kinase CbhK Mb2225c 64 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 31792209 Common glmU Probable UDP-N-acetylglucosamine pyrophosphorylase glmU Mb1046c 228 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 31793463 Common - conserved hypothetical protein [SECOND PART] Mb2307c 2 None None None 31792873 Common - PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER Mb1713c 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 31792800 Common lgt prolipoprotein diacylglyceryl transferase Mb1640 196 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 31794016 Common infB translation initiation factor IF-2 Mb2864c 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 31793259 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb2102c 1 None None None 31793779 Common - hypothetical protein Mb2626 4 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 31792142 Common - POSSIBLE OXIDOREDUCTASE Mb0978c 98 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31792838 Common PE_PGRS30 PE-PGRS FAMILY PROTEIN Mb1679c 1 None None None 31792500 Common atpH PROBABLE ATP SYNTHASE DELTA CHAIN ATPH Mb1339 89 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 31793174 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb2017c 87 COG0640 ArsR, Predicted transcriptional regulators Transcription 31793437 Common - hypothetical protein Mb2281c 61 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 31792507 Common - POSSIBLE TRANSPOSASE [FIRST PART] Mb1346c 31 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 31793770 Common secF preprotein translocase subunit SecF Mb2617c 201 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 31794678 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Mb3532c 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31791285 Common ctpI PROBABLE CATION-TRANSPORTER ATPASE I CTPI Mb0111c 210 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 31793385 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2229 11 None None None 31792253 Common - hypothetical protein Mb1091 24 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 31794908 Common - TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ARAC/XYLS-FAMILY) Mb3763 66 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 31791223 Common ino1 MYO-INOSITOL-1-PHOSPHATE SYNTHASE INO1 (Inositol 1-phosphate synthetase) (D-glucose 6-phosphate cycloaldolase) (Glucose 6-phosphate cyclase) (Glucocycloaldolase) Mb0047c 53 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 31793144 Pathogen - hypothetical protein Mb1987 1 COG4691 StbC, Plasmid stability protein General function prediction only 31791617 Common - short chain dehydrogenase Mb0447c 205 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31793704 Common acpS 4'-phosphopantetheinyl transferase Mb2552c 5 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 31791518 Common - hypothetical protein Mb0347 2 None None None 31791910 Common sppA POSSIBLE PROTEASE IV SPPA (ENDOPEPTIDASE IV) (SIGNAL PEPTIDE PEPTIDASE) Mb0745 179 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 31791317 Common - PUTATIVE OXIDOREDUCTASE Mb0144 157 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 31792737 Common frdA fumarate reductase flavoprotein subunit Mb1578 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 31793086 Common - hypothetical protein Mb1927c 28 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 31793508 Common - hypothetical protein Mb2352c 29 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 31792765 Pathogen - Probable phiRv1 phage protein Mb1605c 1 None None None 31793370 Common - hypothetical protein Mb2214 229 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 31793697 Common - hypothetical protein Mb2545c 2 None None None 31794749 Common - hypothetical protein Mb3603 1 None None None 31792917 Common - hypothetical protein Mb1758c 30 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31791250 Common - PROBABLE GLUTAMINE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER GLNQ Mb0074 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 31791612 Common - hypothetical protein Mb0442 63 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 31792052 Common moaC molybdenum cofactor biosynthesis protein C Mb0888 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 31792382 Common sigI RNA polymerase sigma factor SigI Mb1221 87 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 31793677 Common pdhA PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (ALPHA SUBUNIT) PDHA (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE) Mb2525c 155 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 31794355 Common - POSSIBLE PEROXIDASE (NON-HAEM PEROXIDASE) Mb3203 136 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31791555 Pathogen - CONSERVED HYPOTHETICAL GLYCINE RICH PROTEIN Mb0385 1 None None None 31792322 Common - hypothetical protein Mb1159c 7 None None None 31792327 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Mb1164c 139 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 31792405 Common - PUTATIVE GLYCOSYL TRANSFERASE Mb1244c 196 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 31794728 Common - POSSIBLE COA-TRANSFERASE (BETA SUBUNIT) Mb3582 36 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 31793295 Common - Probable ATPase Mb2139c 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 31792978 Common PPE27 PPE FAMILY PROTEIN Mb1818 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794579 Common idsA1 PROBABLE MULTIFUNCTIONAL GERANYLGERANYL PYROPHOSPHATE SYNTHETASE IDSA1 (GGPP SYNTHETASE) (GGPPSASE) (GERANYLGERANYL DIPHOSPHATE SYNTHASE): DIMETHYLALLYLTRANSFERASE (PRENYLTRANSFERASE) (GERANYL-DIPHOSPHATE SYNTHASE) + GERANYLTRANSTRANSFERASE (FARNESYL-DIPH Mb3431c 238 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 31791956 Common aldA PROBABLE ALDEHYDE DEHYDROGENASE NAD DEPENDANT ALDA (ALDEHYDE DEHYDROGENASE [NAD+]) Mb0791 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 31791906 Common rplR 50S ribosomal protein L18 Mb0741 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 31792966 Common cyp144 Probable cytochrome p450 144 CYP144 Mb1806 84 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31792448 Common - hypothetical protein Mb1287c 3 None None None 31794485 Common amiA1 POSSIBLE N-ACYL-L-AMINO ACID AMIDOHYDROLASE AMIA1 (N-ACYL-L-AMINO ACID AMIDASE) Mb3333c 159 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 31794966 Common embC INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE EMBC (ARABINOSYLINDOLYLACETYLINOSITOL SYNTHASE) Mb3822 5 None None None 31792390 Pathogen esxK PUTATIVE ESAT-6 LIKE PROTEIN 3 Mb1229 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31794685 Common ilvX hypothetical protein Mb3539c 68 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 31791483 Common PPE5 PPE FAMILY PROTEIN Mb0312c 21 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791816 Common - POSSIBLE GLYOXALASE II (HYDROXYACYLGLUTATHIONE HYDROLASE) (GLX II) Mb0651c 220 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 31791441 Common - hypothetical protein Mb0269c 114 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 31792969 Common - hypothetical protein Mb1809 2 None None None 31791848 Pathogen - hypothetical protein Mb0683 1 None None None 31792059 Common cspB PROBABLE COLD SHOCK-LIKE PROTEIN B CSPB Mb0895 162 COG1278 CspC, Cold shock proteins Transcription 31793840 Common - POSSIBLE EXPORTED ALANINE AND VALINE RICH PROTEIN Mb2687 1 None None None 31794602 Common - hypothetical protein Mb3455c 28 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 31794992 Common - hypothetical protein Mb3848 7 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 31794669 Common - CONSERVED HYPOTHETICAL MCE ASSOCIATED ALANINE AND VALINE RICH PROTEIN Mb3523c 2 None None None 31794740 Common fadE33 PROBABLE ACYL-COA DEHYDROGENASE FADE33 Mb3594 49 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31791648 Common umaA1 POSSIBLE MYCOLIC ACID SYNTHASE UMAA1 Mb0478 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 31792820 Common - Possible drug efflux membrane protein Mb1660 125 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31792536 Common rph ribonuclease PH Mb1375 184 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 31792576 Common - PROBABLE EXPORT OR MEMBRANE PROTEIN Mb1417 8 None None None 31792017 Common - PUTATIVE TRANSPOSASE (FRAGMENT) Mb0852 4 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 31793981 Pathogen - hypothetical protein Mb2828 1 None None None 31792069 Common - POSSIBLE RRNA METHYLTRANSFERASE (RRNA METHYLASE) Mb0905 212 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 31793222 Common - Probable sugar-transport integral membrane protein ABC transporter Mb2065c 151 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 31791692 Common hemC porphobilinogen deaminase Mb0523 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 31792021 Pathogen PE_PGRS13 PE-PGRS FAMILY PROTEIN Mb0856 1 COG4907 COG4907, Predicted membrane protein Function unknown 31793847 Common - hypothetical protein Mb2694c 49 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31793407 Pathogen - conserved hypothetical protein [FIRST PART] Mb2251 1 COG3826 COG3826, Uncharacterized protein conserved in bacteria Function unknown 31793589 Common - hypothetical protein Mb2433c 83 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 31793995 Common - hypothetical protein Mb2843c 6 COG1332 COG1332, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 31792741 Common mmpS6 PROBABLE CONSERVED MEMBRANE PROTEIN MMPS6 Mb1582 1 None None None 31793977 Common - hypothetical protein Mb2824c 56 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 31791688 Common mmpS2 PROBABLE CONSERVED MEMBRANE PROTEIN MMPS2 Mb0518 1 None None None 31794805 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3659 7 None None None 31792729 Common - POSSIBLE FATTY ACYL-COA REDUCTASE Mb1570 225 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 31792674 Common moxR1 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN MOXR1 Mb1515 177 COG0714 COG0714, MoxR-like ATPases General function prediction only 31793837 Pathogen - HYPOTHETICAL ARGININE RICH PROTEIN Mb2684 1 None None None 31793368 Common - hypothetical protein Mb2212c 6 None None None 31793583 Common lepA GTP-binding protein LepA Mb2427c 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 31794007 Common echA16 enoyl-CoA hydratase Mb2855 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31792125 Common pstA2 PHOSPHATE-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER PSTA2 Mb0961 224 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 161511530 Common - 2-dehydropantoate 2-reductase Mb2603 57 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 31795009 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb3865 6 COG5373 COG5373, Predicted membrane protein Function unknown 31792453 Common - hypothetical protein Mb1292c 11 None None None 31791320 Common - hypothetical protein Mb0147 18 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 31795088 Common - PUTATIVE HYDROLASE Mb3946 88 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 31791927 Common - PUTATIVE TRANSPOSASE (FRAGMENT) Mb0762 5 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 31794086 Common - hypothetical protein Mb2934c 12 None None None 31793652 Common aglA PROBABLE ALPHA-GLUCOSIDASE AGLA (MALTASE) (GLUCOINVERTASE) (GLUCOSIDOSUCRASE) (MALTASE-GLUCOAMYLASE) (LYSOSOMAL ALPHA-GLUCOSIDASE) (ACID MALTASE) Mb2498 161 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 31791337 Common PE3 PE FAMILY PROTEIN Mb0164c 1 None None None 31793060 Common - hypothetical protein Mb1901c 10 None None None 31792071 Common - hypothetical protein Mb0907c 18 None None None 31794166 Pathogen - hypothetical protein Mb3014c 1 None None None 31791882 Pathogen - CONSERVED HYPOTHETICAL PROTEIN [FIRST PART] Mb0717 1 None None None 31792289 Common - POSSIBLE GLYCOSYL HYDROLASE Mb1126 106 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 31791789 Common - hypothetical protein Mb0623 1 None None None 31794558 Common - hypothetical protein Mb3410 102 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 31794751 Common - TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb3605 7 COG1309 AcrR, Transcriptional regulator Transcription 31791411 Common gabD1 succinic semialdehyde dehydrogenase Mb0239c 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 31794737 Common fadD3 acyl-CoA synthetase Mb3591 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31794246 Pathogen - hypothetical protein Mb3094 1 None None None 31794381 Common - POSSIBLE DNA-METHYLTRANSFERASE (MODIFICATION METHYLASE) Mb3229 56 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 31791901 Common rplX 50S ribosomal protein L24 Mb0736 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 31793591 Common rpsT 30S ribosomal protein S20 Mb2435 144 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 31791546 Common - POSSIBLE MEMBRANE OXIDOREDUCTASE Mb0376c 19 COG3427 COG3427, Uncharacterized conserved protein Function unknown 31792648 Common qor PROBABLE QUINONE REDUCTASE QOR (NADPH:quinone reductase) (Zeta-crystallin homolog protein) Mb1489c 184 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 31794541 Common - hypothetical protein Mb3393 53 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 31794394 Common - POSSIBLE ACETYLTRANSFERASE Mb3242 55 COG0456 RimI, Acetyltransferases General function prediction only 31793582 Common lppR PROBABLE CONSERVED LIPOPROTEIN LPPR Mb2426c 1 None None None 31792755 Common bioF1 8-amino-7-oxononanoate synthase Mb1596 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 31791632 Pathogen - hypothetical protein Mb0462 1 None None None 31792263 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb1101 28 COG4760 COG4760, Predicted membrane protein Function unknown 31793059 Common - Probable reductase Mb1900c 232 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 31791407 Common php PROBABLE PHOSPHOTRIESTERASE PHP (PARATHION HYDROLASE) (PTE) (ARYLDIALKYLPHOSPHATASE) (PARAOXONASE) (A-ESTERASE) (ARYLTRIPHOSPHATASE) (PARAOXON HYDROLASE) Mb0235c 35 COG1735 Php, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 31792704 Common - hypothetical protein Mb1545 65 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 31791587 Common ackA acetate kinase Mb0417 162 COG0282 ackA, Acetate kinase Energy production and conversion 31793988 Common - PUTATIVE TRANSPOSASE [SECOND PART] Mb2836 62 None None None 31792939 Common - hypothetical protein Mb1780 121 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 31794309 Common devR TWO COMPONENT TRANSCRIPTIONAL REGULATORY PROTEIN DEVR (PROBABLY LUXR/UHPA-FAMILY) Mb3157c 181 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 31792115 Common pstS3 PERIPLASMIC PHOSPHATE-BINDING LIPOPROTEIN PSTS3 (PBP-3) (PSTS3) (PHOS1) Mb0951 111 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 31792440 Common - hypothetical protein Mb1279c 10 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 31791564 Common PPE9 PPE FAMILY PROTEIN Mb0394c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793034 Common gnd1 6-phosphogluconate dehydrogenase Mb1875c 178 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 31793326 Common - Possible conserved transmembrane protein Mb2170c 18 COG0762 COG0762, Predicted integral membrane protein Function unknown 31791889 Common rplB 50S ribosomal protein L2 Mb0724 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 31794431 Common rubA PROBABLE RUBREDOXIN RUBA Mb3279c 107 COG1773 COG1773, Rubredoxin Energy production and conversion 31791273 Pathogen - hypothetical protein Mb0098c 1 None None None 31792960 Common - PROBABLE OXIDOREDUCTASE Mb1800 45 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 31794266 Common - hypothetical protein Mb3114 28 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 31792815 Common polA DNA polymerase I Mb1655 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 31793853 Common - CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN Mb2700 101 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 31794694 Common cyp142a PROBABLE CYTOCHROME P450 MONOOXYGENASE 142 CYP142A [FIRST PART] Mb3548c 46 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31792063 Common - POSSIBLE CONSERVED EXPORTED PROTEIN Mb0899c 4 None None None 31793163 Common cfp21 PROBABLE CUTINASE PRECURSOR CFP21 Mb2006c 3 COG3946 VirJ, Type IV secretory pathway, VirJ component Intracellular trafficking and secretion 31791865 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY) Mb0700 22 COG1309 AcrR, Transcriptional regulator Transcription 31793832 Pathogen - hypothetical protein Mb2679c 1 None None None 31794206 Common fixB PROBABLE ELECTRON TRANSFER FLAVOPROTEIN (ALPHA-SUBUNIT) FIXB (ALPHA-ETF) (ELECTRON TRANSFER FLAVOPROTEIN LARGE SUBUNIT) (ETFLS) Mb3054c 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 31791291 Common gmhA PROBABLE PHOSPHOHEPTOSE ISOMERASE GMHA Mb0117 128 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 31791801 Common galT PROBABLE GALACTOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALT Mb0635 78 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 31793121 Common - hypothetical protein Mb1964c 15 None None None 31793192 Common - hypothetical protein Mb2035 4 COG5562 COG5562, Phage envelope protein General function prediction only 31794447 Common - CONSERVED HYPOTHETICAL PROTEIN (CPSA-RELATED PROTEIN) Mb3295 62 COG1316 LytR, Transcriptional regulator Transcription 31792431 Common sugC PROBABLE SUGAR-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER SUGC Mb1270 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 31792698 Common - hypothetical protein Mb1539 15 COG5285 COG5285, Protein involved in biosynthesis of mitomycin antibiotics/polyketide fumonisin Secondary metabolites biosynthesis, transport, and catabolism 31793780 Common - hypothetical protein Mb2627 4 None None None 31794822 Pathogen PE_PGRS60 PE-PGRS FAMILY-RELATED PROTEIN Mb3676 1 None None None 31793533 Common PPE40 PPE FAMILY PROTEIN Mb2377c 2 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794648 Common - hypothetical protein Mb3501 9 None None None 31791705 Common - hypothetical protein Mb0536c 3 None None None 31791594 Common thiS sulfur carrier protein ThiS Mb0424 1 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 31794710 Common - 4-hydroxy-2-ketovalerate aldolase Mb3564c 195 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 31791639 Common - CONSERVED HYDROPHOBIC PROTEIN Mb0469 1 None None None 31791834 Common - POSSIBLE SUGAR KINASE Mb0669 29 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 31793065 Common - hypothetical protein Mb1906 7 None None None 31792100 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0936 1 None None None 31791388 Common - hypothetical protein Mb0216 3 None None None 31793036 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1877c 31 COG3682 COG3682, Predicted transcriptional regulator Transcription 31794586 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb3439c 46 COG1309 AcrR, Transcriptional regulator Transcription 31794119 Common mmpL7 CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL7 Mb2967 7 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31792300 Common xseB exodeoxyribonuclease VII small subunit Mb1137c 35 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 31791757 Common - hypothetical protein Mb0590c 61 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 31793974 Pathogen - hypothetical protein Mb2821c 1 None None None 31791421 Common fadA2 acetyl-CoA acetyltransferase Mb0249 172 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31793569 Common cysH phosphoadenosine phosphosulfate reductase Mb2413 155 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 31793516 Common mez PROBABLE [NAD] DEPENDENT MALATE OXIDOREDUCTASE MEZ (MALIC ENZYME) (NAD-MALIC ENZYME) (MALATE DEHYDROGENASE (OXALOACETATE DECARBOXYLATING)) (PYRUVIC-MALIC CARBOXYLASE) (NAD-ME) Mb2360 192 COG0281 SfcA, Malic enzyme Energy production and conversion 31791578 Common mmpL1b PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL1B [SECOND PART] Mb0408c 51 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31792182 Common - CONSERVED HYPOTHETICAL SERINE RICH PROTEIN Mb1018c 67 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 31792231 Pathogen PPE15 PPE FAMILY PROTEIN Mb1068c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791596 Common lpqL PROBABLE LIPOPROTEIN AMINOPEPTIDASE LPQL Mb0426 59 COG2234 Iap, Predicted aminopeptidases General function prediction only 31793425 Common kasA 3-oxoacyl-(acyl carrier protein) synthase II Mb2269 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792757 Common - hypothetical protein Mb1598 5 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 31792483 Pathogen - hypothetical protein Mb1322 1 None None None 31792189 Common - hypothetical protein Mb1025 62 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 31792947 Common cut1 PROBABLE CUTINASE CUT1 Mb1788 3 None None None 31792128 Common - POSSIBLE BIFUNCTIONAL ENZYME: 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE) + CYCLASE/DEHYDRASE Mb0964 178 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 31792940 Common - hypothetical protein Mb1781 2 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 31791298 Common fusA2b elongation factor G Mb0124c 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 31791774 Common mce2Da MCE-FAMILY PROTEIN MCE2DA [FIRST PART] Mb0607 7 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31794031 Common - hypothetical protein Mb2879 15 COG2267 PldB, Lysophospholipase Lipid metabolism 31793914 Pathogen PE_PGRS47 PE-PGRS FAMILY PROTEIN Mb2761 1 None None None 31792028 Common pip PROBABLE PROLINE IMINOPEPTIDASE PIP (PROLYL AMINOPEPTIDASE) (PAP) Mb0863c 122 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31793574 Pathogen PE_PGRS41 PE-PGRS FAMILY PROTEIN Mb2418 1 COG4907 COG4907, Predicted membrane protein Function unknown 31791887 Common rplD 50S ribosomal protein L4 Mb0722 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 31793925 Common - hypothetical protein Mb2772 31 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31794304 Common - hypothetical protein Mb3152c 11 None None None 31792750 Common treX Maltooligosyltrehalose synthase TreX Mb1591c 154 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 31793390 Common gcvT glycine cleavage system aminomethyltransferase T Mb2234c 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 31794893 Common dnaZX DNA polymerase III subunits gamma and tau Mb3748c 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 31792581 Common PPE20 PPE FAMILY PROTEIN Mb1422 3 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791368 Common - hypothetical protein Mb0196 97 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 31792844 Common argR arginine repressor Mb1685 80 COG1438 ArgR, Arginine repressor Transcription 31794820 Pathogen PE33 PE FAMILY PROTEIN Mb3674 1 None None None 31791804 Common - POSSIBLE MEMBRANE PROTEIN Mb0638 1 None None None 31794371 Pathogen - hypothetical protein Mb3219c 1 None None None 31791509 Common - POSSIBLE DEHYDROGENASE/REDUCTASE Mb0338 85 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 31792089 Common - POSSIBLE CONSERVED EXPORTED OR MEMBRANE PROTEIN Mb0925 5 None None None 31793107 Common - hypothetical protein Mb1949c 2 None None None 31792893 Pathogen - hypothetical protein Mb1733c 1 None None None 31792561 Pathogen - hypothetical protein Mb1400c 3 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 31795081 Common - hypothetical protein Mb3938 61 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 31794928 Common proV POSSIBLE OSMOPROTECTANT (GLYCINE BETAINE/CARNITINE/CHOLINE/L-PROLINE) TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER PROV Mb3784c 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 31791534 Common purA adenylosuccinate synthetase Mb0364c 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 31794508 Pathogen - HYPOTHETICAL PROTEIN [FIRST PART] Mb3356 1 None None None 31794321 Common nuoA NADH dehydrogenase subunit A Mb3169 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 31794998 Common papA1 PROBABLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA1 Mb3854c 7 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31793804 Common - hypothetical protein Mb2651 12 COG2345 COG2345, Predicted transcriptional regulator Transcription 31794295 Common moeB2 PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN MOEB2 (MPT-SYNTHASE SULFURYLASE) (MOLYBDOPTERIN SYNTHASE SULPHURYLASE) Mb3143 227 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 31794074 Common - hypothetical protein Mb2922c 86 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 31791219 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY MARR-FAMILY) Mb0043c 44 COG1846 MarR, Transcriptional regulators Transcription 31792615 Common - hypothetical protein Mb1456 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 31791452 Common - hypothetical protein Mb0280 49 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 31794846 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY CRP/FNR-FAMILY) Mb3700 164 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 31792151 Pathogen lprP POSSIBLE LIPOPROTEIN LPRP Mb0987c 1 None None None 31793458 Common pitB Putative phosphate-transport permease PitB Mb2302 169 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 31792131 Pathogen - hypothetical protein Mb0967 1 None None None 31793511 Pathogen PE23 PE FAMILY PROTEIN Mb2355 1 None None None 31791714 Pathogen PE_PGRS6a PE-PGRS FAMILY PROTEIN [FIRST PART] Mb0545 1 None None None 31791642 Pathogen - PROBABLE CONSERVED MEMBRANE PROTEIN Mb0472 1 None None None 31792114 Common - short chain dehydrogenase Mb0950c 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31794914 Common - TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ARSR-FAMILY) Mb3770 70 COG0640 ArsR, Predicted transcriptional regulators Transcription 31794455 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit Mb3303c 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 31793067 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN [FIRST PART] Mb1908 174 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31794539 Common folD PROBABLE BIFUNCTIONAL PROTEIN FOLD: METHYLENETETRAHYDROFOLATE DEHYDROGENASE + METHENYLTETRAHYDROFOLATE CYCLOHYDROLASE Mb3391c 223 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 31794955 Common - POSSIBLE L-RHAMNOSYLTRANSFERASE Mb3811 13 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 31794497 Common sdhC PROBABLE SUCCINATE DEHYDROGENASE (CYTOCHROME B-556 SUBUNIT) SDHC (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE) Mb3345 24 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 31794278 Common - hypothetical protein Mb3126c 7 None None None 31791897 Common atsAb POSSIBLE ARYLSULFATASE ATSAb [SECOND PART] (ARYL-SULFATE SULPHOHYDROLASE) (ARYLSULPHATASE) Mb0732 48 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 31793229 Common lppI Probable lipoprotein lppI Mb2072 1 None None None 31792307 Common - hypothetical protein Mb1144 14 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794441 Common fbiA PROBABLE F420 BIOSYNTHESIS PROTEIN FBIA Mb3289 39 COG0391 COG0391, Uncharacterized conserved protein Function unknown 31794098 Common smc PROBABLE CHROMOSOME PARTITION PROTEIN SMC Mb2946c 178 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 31795070 Common - hypothetical protein Mb3926c 7 COG3953 COG3953, SLT domain proteins General function prediction only 31791184 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb0007 17 None None None 31792478 Common cysN bifunctional sulfate adenylyltransferase subunit 1/adenylylsulfate kinase protein Mb1317 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 31793678 Common citE PROBABLE CITRATE (PRO-3S)-LYASE (BETA SUBUNIT) CITE (CITRASE) (CITRATASE) (CITRITASE) (CITRIDESMOLASE) (CITRASE ALDOLASE) Mb2526c 109 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 31791755 Common - nicotinate phosphoribosyltransferase Mb0588c 123 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 31794994 Common papA2 POSSIBLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA2 Mb3850c 5 None None None 31793898 Common dapF diaminopimelate epimerase Mb2745c 190 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 31792370 Common - hypothetical protein Mb1209c 37 COG1695 COG1695, Predicted transcriptional regulators Transcription 31794938 Common - hypothetical protein Mb3794 4 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 31791934 Common - hypothetical protein Mb0769 2 None None None 31791381 Common - POSSIBLE EXPORTED PROTEIN Mb0209 1 None None None 31793153 Common - hypothetical protein Mb1996 2 None None None 31793269 Common - hypothetical protein Mb2113 5 None None None 31791206 Pathogen - hypothetical protein Mb0030 1 None None None 31791962 Common - PROBABLE CONSERVED EXPORTED PROTEIN Mb0797c 5 COG0627 COG0627, Predicted esterase General function prediction only 31793376 Common - Probable conserved transmembrane protein Mb2220c 1 None None None 31794201 Common - PROBABLE TRANSPOSASE Mb3049c 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 31794715 Common PPE63 PPE FAMILY PROTEIN Mb3569 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792335 Common - PROBABLE INTEGRAL MEMBRANE PROTEIN Mb1172 4 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 31792719 Common - hypothetical protein Mb1560 113 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 31791969 Common ptrB PROBABLE PROTEASE II PTRB (OLIGOPEPTIDASE B) Mb0804 100 COG1770 PtrB, Protease II Amino acid transport and metabolism 31792922 Common - hypothetical protein Mb1763c 14 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 31794198 Common esxS PE FAMILY PROTEIN Mb3046c 1 None None None 31794172 Common serA1 PROBABLE D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA1 (PGDH) Mb3020c 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 31794975 Common fadD32 acyl-CoA synthetase Mb3831c 194 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792049 Common - PROBABLE DNA HELICASE Mb0884c 72 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 31793241 Common rpmB 50S ribosomal protein L28 Mb2084c 86 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 31793220 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb2063c 15 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 31794140 Common purU PROBABLE FORMYLTETRAHYDROFOLATE DEFORMYLASE PURU (FORMYL-FH(4) HYDROLASE) Mb2988 217 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 31794168 Common gltX glutamyl-tRNA synthetase Mb3016c 243 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 31793618 Common nadE NAD synthetase Mb2464c 169 COG0171 NadE, NAD synthase Coenzyme metabolism 31792793 Common chaA Probable ionic transporter integral membrane protein chaA Mb1633 44 COG0387 ChaA, Ca2+/H+ antiporter Inorganic ion transport and metabolism 31793598 Common - PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) Mb2442c 163 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 31791280 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0105 27 COG3336 COG3336, Predicted membrane protein Function unknown 31794229 Common nrdE ribonucleotide-diphosphate reductase subunit alpha Mb3077c 218 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 31793520 Pathogen - hypothetical protein Mb2364 1 None None None 31793000 Common mgtC POSSIBLE Mg2+ TRANSPORT P-TYPE ATPASE C MGTC Mb1841 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 31794524 Common metC O-acetylhomoserine aminocarboxypropyltransferase Mb3372 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 31794562 Common lytB1 PROBABLE LYTB-RELATED PROTEIN LYTB1 Mb3414c 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 31792712 Common - Probable glycosyltransferase Mb1553c 31 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 31794123 Common pks1 PROBABLE POLYKETIDE SYNTHASE PKS1 Mb2971c 222 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794986 Pathogen PE_PGRS62 PE-PGRS FAMILY PROTEIN Mb3842 1 None None None 31794556 Common echA18 PROBABLE ENOYL-COA HYDRATASE ECHA18 (ENOYL HYDRASE) (UNSATURATED ACYL-COA HYDRATASE) (CROTONASE) Mb3408 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31791339 Common - PUTATIVE OXIDOREDUCTASE Mb0166 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 31793056 Common - hypothetical protein Mb1897 112 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 31793360 Common - 1-acylglycerol-3-phosphate O-acyltransferase Mb2204c 166 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 31792256 Common - hypothetical protein Mb1094 8 None None None 31794415 Common - HYPOTHETICAL ALANINE ARGININE PROLINE RICH PROTEIN Mb3263 3 None None None 31792919 Common gabD2 succinic semialdehyde dehydrogenase Mb1760 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 31793777 Common ruvA Holliday junction DNA helicase motor protein Mb2624c 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 31793825 Common - hypothetical protein Mb2672c 79 COG1742 COG1742, Uncharacterized conserved protein Function unknown 31792653 Common - POSSIBLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb1494c 14 None None None 31791287 Pathogen PE_PGRS1 PE-PGRS FAMILY PROTEIN Mb0113 1 COG4907 COG4907, Predicted membrane protein Function unknown 31794618 Common mrsA PROBABLE PHOSPHO-SUGAR MUTASE / MRSA PROTEIN HOMOLOG Mb3471c 238 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 31794113 Common drrA PROBABLE DAUNORUBICIN-DIM-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER DRRA Mb2961 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 31791377 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb0205 1 None None None 31791656 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb0486 6 None None None 31791761 Common - hypothetical protein Mb0594 36 COG1656 COG1656, Uncharacterized conserved protein Function unknown 31793960 Common lppU PROBABLE LIPOPROTEIN LPPU Mb2807c 3 None None None 31793179 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb2022c 32 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 31791974 Common - hypothetical protein Mb0809c 13 None None None 31791836 Common rplL 50S ribosomal protein L7/L12 Mb0671 195 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 31793172 Common ctpG PROBABLE METAL CATION TRANSPORTER P-TYPE ATPASE G CTPG Mb2015c 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 31793042 Common ureG Urease accessory protein ureG Mb1883 98 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 31794024 Common cysG POSSIBLE MULTIFUNCTIONAL ENZYME SIROHEME SYNTHASE CYSG: UROPORPHYRIN-III C-METHYLTRANSFERASE (UROGEN III METHYLASE) (SUMT) (UROPORPHYRINOGEN III METHYLASE) (UROM) + PRECORRIN-2 OXIDASE + FERROCHELATASE Mb2872c 200 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 31794358 Common - HYPOTHETICAL ALANINE RICH PROTEIN Mb3206c 2 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31791623 Common sigK RNA polymerase sigma factor SigK Mb0453c 107 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 31794401 Pathogen - hypothetical protein Mb3249c 1 None None None 31792658 Common csd PROBABLE CYSTEINE DESULFURASE CSD Mb1499 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 31791985 Common - IS1547 transposase Mb0820 46 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 31793499 Common uspA PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER USPA Mb2343 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 31793871 Common - hypothetical protein Mb2718c 19 None None None 31794596 Common - hypothetical protein Mb3449c 3 None None None 31793796 Common - lipid A biosynthesis lauroyl acyltransferase Mb2643c 25 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 31791576 Common fadE7 PROBABLE ACYL-COA DEHYDROGENASE FADE7 Mb0406c 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31794676 Common yrbE4B CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4B Mb3530c 43 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 31793314 Common - hypothetical protein Mb2158c 17 None None None 31794014 Common - hypothetical protein Mb2862c 77 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 31794855 Common - PROBABLE LYASE Mb3709 181 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 31792509 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase Mb1348 213 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 31792236 Pathogen - hypothetical protein Mb1074 1 None None None 31792245 Common - PUTATIVE INTEGRASE (FRAGMENT) Mb1083 2 None None None 31793494 Common - hypothetical protein Mb2338 4 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 31794857 Pathogen - hypothetical protein Mb3711c 1 None None None 31794332 Common nuoL NADH dehydrogenase subunit L Mb3180 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 31791707 Common - hypothetical protein Mb0538 20 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 31793662 Common plsC POSSIBLE TRANSMEMBRANE PHOSPHOLIPID BIOSYNTHESIS BIFUNCTIONNAL ENZYME PLSC: PUTATIVE L-3-PHOSPHOSERINE PHOSPHATASE (O-PHOSPHOSERINE PHOSPHOHYDROLASE) (PSP) (PSPASE) + 1-ACYL-SN-GLYCEROL-3-PHOSPHATE ACYLTRANSFERASE (1-AGP ACYLTRANSFERASE) (1-AGPAT) (LYSOPH Mb2508c 165 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 31792061 Common fadE10 PROBABLE ACYL-COA DEHYDROGENASE FADE10 Mb0897 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31792160 Common echA7 enoyl-CoA hydratase Mb0996c 177 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31792643 Common tkt transketolase Mb1484c 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 31793969 Common truB tRNA pseudouridine synthase B Mb2816c 244 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 31793160 Common nrdF ribonucleotide-diphosphate reductase subunit beta Mb2003c 145 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 31793906 Common - hypothetical protein Mb2753 42 COG4422 COG4422, Bacteriophage protein gp37 Function unknown 31794886 Common - hypothetical protein Mb3741c 8 None None None 31794862 Common - hypothetical protein Mb3716 10 None None None 31792196 Common pabB para-aminobenzoate synthase component I Mb1032c 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 31793623 Common rplU 50S ribosomal protein L21 Mb2469c 213 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 31792223 Common kdpC Probable Potassium-transporting ATPase C chain KDPC (Potassium-translocating ATPase C chain) (ATP phosphohydrolase [potassium-transporting] C chain) (Potassium binding and translocating subunit C) Mb1060 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 31794253 Common - hypothetical protein Mb3101 5 None None None 31792228 Common - IS1560 transposase Mb1065c 4 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 31792271 Common greA transcription elongation factor GreA Mb1109c 200 COG0782 GreA, Transcription elongation factor Transcription 31791523 Common - hypothetical protein Mb0353 3 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 31793736 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb2583c 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 31793630 Common - hypothetical protein Mb2476c 46 COG3268 COG3268, Uncharacterized conserved protein Function unknown 31794889 Common - hypothetical protein Mb3744 20 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 31792958 Common - hypothetical protein Mb1798 19 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 31793120 Common - short chain dehydrogenase Mb1963c 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31792080 Common - PROBABLE MONOOXYGENASE Mb0916 81 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 31792356 Common narH PROBABLE RESPIRATORY NITRATE REDUCTASE (BETA CHAIN) NARH Mb1194 147 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 31792426 Common - hypothetical protein Mb1265c 5 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 31793284 Common - hypothetical protein Mb2128 40 COG4279 COG4279, Uncharacterized conserved protein Function unknown 31794155 Common - PROBABLE RESOLVASE Mb3003c 21 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 31793755 Common aspS aspartyl-tRNA synthetase Mb2602c 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31791395 Common lipW POSSIBLE ESTERASE LIPW Mb0223c 114 COG0657 Aes, Esterase/lipase Lipid metabolism 31794510 Common embR2 POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN EMBR2 Mb3358 46 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 31793011 Common secA2 preprotein translocase subunit SecA Mb1852 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 31793810 Common - hypothetical protein Mb2657c 31 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 31795030 Common - hypothetical protein Mb3886c 72 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 31795057 Common - POSSIBLE SECRETED PROTEASE Mb3913c 78 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 31791666 Common - MANNOSYLTRANSFERASE Mb0496 155 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 31792910 Common - biotin carboxylase-like protein Mb1751 14 COG0439 AccC, Biotin carboxylase Lipid metabolism 31792045 Common - hypothetical protein Mb0880 8 None None None 31793874 Common ppgK POLYPHOSPHATE GLUCOKINASE PPGK (POLYPHOSPHATE-GLUCOSE PHOSPHOTRANSFERASE) Mb2721 71 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 31794032 Common mtr mycothione/glutathione reductase Mb2880 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 31791856 Common fadE8 PROBABLE ACYL-COA DEHYDROGENASE FADE8 Mb0691 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31793683 Common scoB PROBABLE SUCCINYL-COA:3-KETOACID-COENZYME A TRANSFERASE (BETA SUBUNIT) SCOB (3-OXO-ACID:COA TRANSFERASE) (OXCT B) (SUCCINYL CoA:3-OXOACID CoA-TRANSFERASE) Mb2531c 97 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 31793142 Pathogen - hypothetical protein Mb1985c 1 None None None 31791494 Common - POSSIBLE BETA-1,3-GLUCANASE PRECURSOR Mb0323 21 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 31793712 Common - hypothetical protein Mb2559Ac 6 None None None 31792853 Common cyp139 Probable cytochrome P450 139 CYP139 Mb1694c 80 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31792144 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0980 4 None None None 31793090 Common - D-tyrosyl-tRNA deacylase Mb1932c 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 31793099 Common - hypothetical protein Mb1941c 1 None None None 31793529 Common dgt deoxyguanosinetriphosphate triphosphohydrolase-like protein Mb2373c 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 31791406 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb0234c 3 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794287 Pathogen - hypothetical protein Mb3135 1 None None None 31792368 Common - hypothetical protein Mb1207c 1 None None None 31791872 Common - PUTATIVE FERREDOXIN REDUCTASE Mb0707 236 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 31793186 Common otsB1 PROBABLE TREHALOSE-6-PHOSPHATE PHOSPHATASE OTSB1 (TREHALOSE-PHOSPHATASE) (TPP) Mb2029 104 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 31792139 Common - hypothetical protein Mb0975c 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 31793720 Common aroB 3-dehydroquinate synthase Mb2567c 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 31793603 Common - PROBABLE TRANSPOSASE [SECOND PART] Mb2447c 69 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 31793613 Pathogen - hypothetical protein Mb2459c 1 None None None 31791410 Common nrdB ribonucleotide-diphosphate reductase subunit beta Mb0238 16 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 31793049 Common modC PROBABLE MOLYBDENUM-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER MODC Mb1890 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 31793852 Common - hypothetical protein Mb2699 19 None None None 31792905 Common - hypothetical protein Mb1745 7 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 31794136 Pathogen - hypothetical protein Mb2984c 1 None None None 31791791 Common - hypothetical protein Mb0625 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 31793070 Common - hypothetical protein Mb1911 7 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 31793787 Common - hypothetical protein Mb2634 2 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794337 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb3185c 60 COG1309 AcrR, Transcriptional regulator Transcription 31791782 Common - PROBABLE TWO COMPONENT SENSOR KINASE [SECOND PART] Mb0616c 126 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 31791996 Common purF amidophosphoribosyltransferase Mb0831 237 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 31792497 Common atpB F0F1 ATP synthase subunit A Mb1336 206 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 31791689 Common mmpL2 PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL2 Mb0519 72 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31793691 Common orn oligoribonuclease Mb2539 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 31791345 Common yrbE1A CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE1A Mb0173 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 31792773 Common - Partial REP13E12 repeat protein Mb1613c 7 None None None 31794315 Common fadE24 PROBABLE ACYL-CoA DEHYDROGENASE FADE24 Mb3163 142 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31793698 Pathogen - hypothetical protein Mb2546c 2 None None None 31792762 Common - Probable phiRV1 phage protein Mb1602c 30 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 31793445 Common cyp124 Probable cytochrome P450 124 CYP124 Mb2289 70 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31792261 Common echA8 enoyl-CoA hydratase Mb1099c 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31793717 Common pepQ PUTATIVE CYTOPLASMIC PEPTIDASE PEPQ Mb2564c 244 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 31793547 Common - hypothetical protein Mb2391c 7 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 31792832 Common - hypothetical protein Mb1672c 23 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 31794141 Common coaD phosphopantetheine adenylyltransferase Mb2989c 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 31793505 Common rocD1 PROBABLE ORNITHINE AMINOTRANSFERASE (N-terminus part) ROCD1 (ORNITHINE--OXO-ACID AMINOTRANSFERASE) Mb2349c 232 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 31791749 Common - PROBABLE METHYLTRANSFERASE/METHYLASE Mb0582 50 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31793983 Common - hypothetical protein Mb2830 11 None None None 31794286 Common agpS POSSIBLE ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE AGPS (ALKYL-DHAP SYNTHASE) (ALKYLGLYCERONE-PHOSPHATE SYNTHASE) Mb3134c 159 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 31793307 Common ansP1 Probable L-asparagine permease ansP1 Mb2151 170 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 31794039 Common - hypothetical protein Mb2887c 11 None None None 31792699 Common - HYPOTHETICAL PROTEIN [FIRST PART] Mb1540 13 None None None 31794134 Common - POSSIBLE GLYCOSYL TRANSFERASE [FIRST PART] Mb2982c 8 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 31793608 Common ahpC ALKYL HYDROPEROXIDE REDUCTASE C PROTEIN AHPC (ALKYL HYDROPEROXIDASE C) Mb2454 223 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 31791658 Common deoC deoxyribose-phosphate aldolase Mb0488 102 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 31791409 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR/ACRR-FAMILY) Mb0237 14 COG1309 AcrR, Transcriptional regulator Transcription 31791797 Pathogen - hypothetical protein Mb0631 1 None None None 31792654 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1495 33 COG2345 COG2345, Predicted transcriptional regulator Transcription 31794363 Pathogen - hypothetical protein Mb3211 1 COG5654 COG5654, Uncharacterized conserved protein Function unknown 31793300 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb2144c 7 COG3918 COG3918, Predicted membrane protein Function unknown 31794835 Common dppB PROBABLE DIPEPTIDE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DPPB Mb3689c 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 31792606 Common ribC riboflavin synthase subunit alpha Mb1447 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 31794068 Pathogen PPE45 PPE FAMILY PROTEIN Mb2916c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794281 Common ftsE PUTATIVE CELL DIVISION ATP-BINDING PROTEIN FTSE (SEPTATION COMPONENT-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER) Mb3129c 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 31792083 Common - hypothetical protein Mb0919 28 None None None 31794158 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase Mb3006c 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 31791731 Pathogen - CONSERVED HYPOTHETICAL PROTEIN [FIRST PART] Mb0564c 1 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31793746 Common glnQ PROBABLE GLUTAMINE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER GLNQ Mb2593 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 31793782 Common - hypothetical protein Mb2629 8 None None None 31791877 Common pqqE PROBABLE COENZYME PQQ SYNTHESIS PROTEIN E PQQE (COENZYME PQQ SYNTHESIS PROTEIN III) Mb0712 177 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 31793311 Common cysQ hypothetical protein Mb2155c 122 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 31794849 Common - hypothetical protein Mb3703c 16 None None None 31792249 Common fadD14 acyl-CoA synthetase Mb1087 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31794793 Common lpqG PROBABLE CONSERVED LIPOPROTEIN LPQG Mb3647 75 COG2968 COG2968, Uncharacterized conserved protein Function unknown 31793897 Common hflX PROBABLE GTP-BINDING PROTEIN HFLX Mb2744c 211 COG2262 HflX, GTPases General function prediction only 31794085 Common rpsP 30S ribosomal protein S16 Mb2933c 112 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 31792358 Common narI PROBABLE RESPIRATORY NITRATE REDUCTASE (GAMMA CHAIN) NARI Mb1196 58 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 31792638 Common - hypothetical protein Mb1479c 2 None None None 31792953 Common - hypothetical protein Mb1794c 5 None None None 31794600 Common gcp O-sialoglycoprotein endopeptidase Mb3453c 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 31792138 Common uvrD1 PROBABLE ATP DEPENDENT DNA HELICASE UVRD1 Mb0974 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 31793282 Common - hypothetical protein Mb2126 5 None None None 31791939 Common fadE9 PROBABLE ACYL-COA DEHYDROGENASE FADE9 Mb0774c 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31792785 Common hisD histidinol dehydrogenase Mb1625 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 31793817 Common - hypothetical protein Mb2664 117 COG1690 RtcB, Uncharacterized conserved protein Function unknown 31792149 Common - hypothetical protein Mb0985 4 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31793013 Common - hypothetical protein Mb1854 22 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 31791495 Common - POSSIBLE MUCONOLACTONE ISOMERASE Mb0324 2 COG4829 CatC1, Muconolactone delta-isomerase Secondary metabolites biosynthesis, transport, and catabolism 31794169 Common - POSSIBLE 2-HYDROXYHEPTA-2,4-DIENE-1,7-DIOATE ISOMERASE (HHDD ISOMERASE) Mb3017c 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 31793092 Common lppD POSSIBLE LIPOPROTEIN LPPD Mb1934c 107 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 31794962 Common - hypothetical protein Mb3818 16 COG2246 COG2246, Predicted membrane protein Function unknown 31791586 Common pta phosphate acetyltransferase Mb0416 178 COG0280 Pta, Phosphotransacetylase Energy production and conversion 31792499 Common atpF F0F1 ATP synthase subunit B Mb1338 82 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 31793945 Common PPE44 PPE FAMILY PROTEIN Mb2792c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791342 Common TB18.5 hypothetical protein Mb0169 7 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 31791380 Common mmpL11 PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL11 Mb0208c 47 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31793123 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1966c 107 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 31793140 Pathogen - hypothetical protein Mb1983c 1 None None None 31794765 Common - CARBONIC ANHYDRASE (CARBONATE DEHYDRATASE) (CARBONIC DEHYDRATASE) Mb3619c 151 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 31791825 Common rplA 50S ribosomal protein L1 Mb0660 221 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 161511524 Common leuA 2-isopropylmalate synthase Mb3737 209 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 31792276 Common - POSSIBLE HEMOLYSIN-LIKE PROTEIN Mb1114c 118 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 31791434 Common PPE2 PPE FAMILY PROTEIN Mb0262c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791808 Common - hypothetical protein Mb0642 3 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 31794853 Common ponA2 PROBABLE BIFUNCTIONAL MEMBRANE-ASSOCIATED PENICILLIN-BINDING PROTEIN 1A/1B PONA2 (MUREIN POLYMERASE) [INCLUDES: PENICILLIN-INSENSITIVE TRANSGLYCOSYLASE (PEPTIDOGLYCAN TGASE) + PENICILLIN-SENSITIVE TRANSPEPTIDASE (DD-TRANSPEPTIDASE)] Mb3707 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 31792299 Common - PROBABLE CHOLESTEROL DEHYDROGENASE Mb1136c 210 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 31793159 Common mpt64 IMMUNOGENIC PROTEIN MPT64 (ANTIGEN MPT64/MPB64) Mb2002c 1 None None None 31793255 Common cobLb Probable precorrin-6y methyltransferase CobLb [SECOND PART] Mb2098c 82 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 31792856 Common - hypothetical protein Mb1697 43 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 31791679 Common - hypothetical protein Mb0509 22 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 31793634 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A Mb2480c 52 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 31792268 Common cbs Probable cystathionine beta-synthase CBS (Serine sulfhydrase) (Beta-thionase) (Hemoprotein H-450) Mb1106 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 31792219 Common kdpD PROBABLE SENSOR PROTEIN KDPD Mb1056c 219 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 31793900 Common - CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN Mb2747c 7 COG3885 COG3885, Uncharacterized conserved protein Function unknown 31791984 Common - PROBABLE OXIDOREDUCTASE [FIRST PART] Mb0819c 233 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 31792989 Common PPE29 PPE FAMILY PROTEIN Mb1829 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793324 Common - Probable transmembrane protein Mb2168c 1 None None None 31794594 Common - HYPOTHETICAL ALANINE AND PROLINE RICH PROTEIN Mb3447c 1 None None None 31791994 Common cpsY POSSIBLE UDP-GLUCOSE-4-EPIMERASE CPSY (GALACTOWALDENASE) (UDP-GALACTOSE-4-EPIMERASE) (URIDINE DIPHOSPHATE GALACTOSE-4-EPIMERASE) (URIDINE DIPHOSPHO-GALACTOSE-4-EPIMERASE) Mb0829c 20 None None None 31794310 Common - hypothetical protein Mb3158c 13 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 31792170 Common PE_PGRS18 PE-PGRS FAMILY PROTEIN Mb1006c 82 COG3391 COG3391, Uncharacterized conserved protein Function unknown 31792711 Common wbbL2 POSSIBLE RHAMNOSYL TRANSFERASE WBBL2 Mb1552 14 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 31793909 Common recA recombinase A Mb2756c 221 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 31793633 Pathogen - hypothetical protein Mb2479c 1 None None None 31794109 Common ppsB PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSB Mb2957 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31791690 Common - hypothetical protein Mb0520 16 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 31792822 Common TB15.3 hypothetical protein Mb1662 81 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 31794041 Common - POSSIBLE PENICILLIN-BINDING LIPOPROTEIN Mb2889c 194 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 31792484 Pathogen - CONSERVED HYPOTHETICAL SECRETED PROTEIN Mb1323c 1 None None None 31793356 Common aroG Probable 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase AroG (DAHP synthetase, phenylalanine-repressible) Mb2200c 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 31793959 Common gpsI polynucleotide phosphorylase/polyadenylase Mb2806c 237 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 31793046 Common - short chain dehydrogenase Mb1887c 73 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31794148 Common - PROBABLE OXIDOREDUCTASE Mb2996 171 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 31794968 Common embB INTEGRAL MEMBRANE INDOLYLACETYLINOSITOL ARABINOSYLTRANSFERASE EMBB (ARABINOSYLINDOLYLACETYLINOSITOL SYNTHASE) Mb3824 5 None None None 31791485 Common - PUTATIVE OXIDOREDUCTASE Mb0314 75 COG0778 NfnB, Nitroreductase Energy production and conversion 31792467 Common lprC PUTATIVE LIPOPROTEIN LPRC Mb1306 3 None None None 31793068 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN [SECOND PART] Mb1909 70 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 31792689 Common mutB methylmalonyl-CoA mutase Mb1530 111 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 31791932 Pathogen PE_PGRS9 PE-PGRS FAMILY PROTEIN Mb0767 1 COG5281 COG5281, Phage-related minor tail protein Function unknown 31793413 Common - hypothetical protein Mb2257 171 COG0546 Gph, Predicted phosphatases General function prediction only 31792415 Common - hypothetical protein Mb1254 5 None None None 31791516 Common - PUTATIVE IRON-SULFUR-BINDING REDUCTASE Mb0345c 89 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 31792113 Common - hypothetical protein Mb0949c 24 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 31794199 Common PPE47 PPE FAMILY PROTEIN Mb3047c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31795011 Common - PROBABLE PHOSPHOGLYCERATE MUTASE (PHOSPHOGLYCEROMUTASE) (PHOSPHOGLYCERATE PHOSPHOMUTASE) Mb3867c 37 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 31792629 Pathogen - Probable conserved Proline, Glycine, Valine-rich secreted protein Mb1470c 1 None None None 31794557 Common amiD PROBABLE AMIDASE AMID (ACYLAMIDASE) (ACYLASE) Mb3409 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 31793979 Pathogen - hypothetical protein Mb2826 1 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 31792619 Common - hypothetical protein Mb1460 28 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 31793552 Common - hypothetical protein Mb2396 13 COG5450 COG5450, Transcription regulator of the Arc/MetJ class Transcription 31793921 Common - N-acetylglutamate synthase Mb2768 76 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 31791703 Pathogen - POSSIBLE METHYLTRANSFERASE/METHYLASE (FRAGMENT) Mb0534 1 None None None 31791863 Common - CONSERVED HYPOTHETICAL THREONINE RICH PROTEIN Mb0698c 3 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 31793845 Common - POSSIBLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb2692 4 None None None 31791870 Common - PROBABLE MEMBRANE PROTEIN Mb0705 1 None None None 31792194 Common - hypothetical protein Mb1030 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 31792349 Common - hypothetical protein Mb1187 11 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 31792575 Common pyrC dihydroorotase Mb1416 213 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 31791402 Common - POSSIBLE CONSERVED PROTEIN Mb0230 195 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 31792225 Common trcR TWO COMPONENT TRANSCRIPTIONAL REGULATOR TRCR Mb1062c 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31792451 Common - hypothetical protein Mb1290 36 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 31793670 Pathogen PE_PGRS43a PE-PGRS FAMILY PROTEIN [FIRST PART] Mb2518c 1 COG4907 COG4907, Predicted membrane protein Function unknown 31794871 Common - hypothetical protein Mb3726c 42 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 31791762 Common - hypothetical protein Mb0595c 3 None None None 31793821 Pathogen - hypothetical protein Mb2668 1 None None None 31794219 Common - PROBABLE CONSERVED ATP-BINDING PROTEIN ABC TRANSPORTER Mb3067c 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 31793738 Common alaS alanyl-tRNA synthetase Mb2585c 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31793319 Common pyrD dihydroorotate dehydrogenase 2 Mb2163 192 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 31795018 Pathogen - PUTATIVE TRANSPOSASE Mb3874 1 None None None 31791357 Common lprO PUTATIVE LIPOPROTEIN LPRO Mb0185c 1 None None None 31793221 Common - Probable sugar-transport ATP-binding protein ABC transporter Mb2064c 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 31794881 Common ask aspartate kinase Mb3736c 233 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 31793524 Common mmpL9b PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL9B [SECOND PART] Mb2368 41 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31791622 Common - hypothetical protein Mb0452c 10 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 31794483 Common lpdA flavoprotein disulfide reductase Mb3331c 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 31791232 Common rpsR 30S ribosomal protein S18 Mb0056 209 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 31791768 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (GNTR-FAMILY) Mb0601 123 COG2186 FadR, Transcriptional regulators Transcription 31794220 Common serB2 phosphoserine phosphatase Mb3068c 165 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 31791600 Common thiD phosphomethylpyrimidine kinase Mb0430c 212 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 31794299 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb3147 23 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 31792517 Common - hypothetical protein Mb1356 14 None None None 31793141 Pathogen - hypothetical protein Mb1984c 1 None None None 31793861 Common - CONSERVED HYPOTHETICAL ALANINE AND VALINE AND GLYCINE RICH PROTEIN Mb2708c 167 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 31794475 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb3323 61 COG1309 AcrR, Transcriptional regulator Transcription 31791370 Common - hypothetical protein Mb0198 21 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 31794997 Common mmpL8 PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN MMPL8 Mb3853c 45 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31794932 Common - PUTATIVE HYDROLASE Mb3788c 43 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 31791303 Pathogen PE_PGRS2 PE-PGRS FAMILY PROTEIN Mb0129 1 None None None 31791332 Common fadE2 PROBABLE ACYL-CoA DEHYDROGENASE FADE2 Mb0159c 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31794527 Common PPE54 PPE FAMILY PROTEIN Mb3375c 16 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792680 Common hemH ferrochelatase Mb1521 85 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 31792982 Common - hypothetical protein Mb1822 1 None None None 31791305 Common treS TREHALOSE SYNTHASE TRES Mb0131 169 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 31791529 Common grpE PROBABLE GRPE PROTEIN (HSP-70 COFACTOR) Mb0359 79 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 31792210 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb1047 122 COG1309 AcrR, Transcriptional regulator Transcription 31793512 Common narK1 PROBABLE NITRITE EXTRUSION PROTEIN 1 NARK1 (NITRITE FACILITATOR 1) Mb2356c 78 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 31793612 Pathogen - hypothetical protein Mb2458c 1 None None None 31792377 Common - POSSIBLE EXPORTED PROTEIN Mb1216c 1 None None None 31794512 Common - PROBABLE TRANSPOSASE FUSION PROTEIN Mb3360 68 COG2128 COG2128, Uncharacterized conserved protein Function unknown 31794490 Common - POSSIBLE ACID PHOSPHATASE (ACID PHOSPHOMONOESTERASE) (PHOSPHOMONOESTERASE) (GLYCEROPHOSPHATASE) Mb3338 11 None None None 31792791 Common hisF imidazole glycerol phosphate synthase subunit HisF Mb1631 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 31792140 Common sucC succinyl-CoA synthetase subunit beta Mb0976 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 31794429 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb3277c 9 COG1309 AcrR, Transcriptional regulator Transcription 31792565 Pathogen - PROBABLE CONSERVED MEMBRANE PROTEIN Mb1405 2 COG3239 DesA, Fatty acid desaturase Lipid metabolism 31792585 Common dfp bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase Mb1426 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 31794120 Common - IS1533 transposase Mb2968 67 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 31792096 Common ctpE PROBABLE METAL CATION TRANSPORTER ATPASE P-TYPE CTPE Mb0932 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 31791522 Common lpqJ PROBABLE LIPOPROTEIN LPQJ Mb0351c 1 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 31792404 Common - hypothetical protein Mb1243 16 None None None 31791841 Common - hypothetical protein Mb0676c 2 COG5450 COG5450, Transcription regulator of the Arc/MetJ class Transcription 31794829 Common - hypothetical protein Mb3683c 148 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 31794000 Common - hypothetical protein Mb2848c 5 COG5551 COG5551, Uncharacterized conserved protein Function unknown 31791330 Common PE2 PE FAMILY PROTEIN Mb0157c 1 None None None 31791293 Common - POSSIBLE SUGAR KINASE Mb0119 29 COG2605 COG2605, Predicted kinase related to galactokinase and mevalonate kinase General function prediction only 31794179 Common ilvH acetolactate synthase 3 regulatory subunit Mb3027c 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 31794442 Common fbiB F420-0--gamma-glutamyl ligase Mb3290 40 COG1478 COG1478, Uncharacterized conserved protein Function unknown 31793073 Common - short chain dehydrogenase Mb1914c 226 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 31791447 Common - hypothetical protein Mb0275c 66 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 31793203 Pathogen - hypothetical protein Mb2046c 1 None None None 31791780 Common - hypothetical protein Mb0614c 2 None None None 31792066 Common PPE13 PPE FAMILY PROTEIN Mb0902c 2 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794582 Common - hypothetical protein Mb3434 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 31793088 Common - POSSIBLE DEHYDROGENASE [SECOND PART] Mb1929 195 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 31794950 Common - PUTATIVE OXIDOREDUCTASE Mb3806 194 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 31791221 Common - POSSIBLE OXIDOREDUCTASE Mb0045c 13 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31792272 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb1110c 5 None None None 31794890 Common - hypothetical protein Mb3745c 6 None None None 31793208 Common - hypothetical protein Mb2051c 63 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 31794412 Common - hypothetical protein Mb3260c 10 None None None 31792553 Common - hypothetical protein Mb1392c 160 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 31793338 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase Mb2182c 213 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 31794341 Common moxR3 PROBABLE METHANOL DEHYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEIN MOXR3 Mb3189c 187 COG0714 COG0714, MoxR-like ATPases General function prediction only 31794305 Common - hypothetical protein Mb3153 7 None None None 31795060 Common - POSSIBLE SECRETED ALANINE AND PROLINE RICH PROTEASE Mb3916c 67 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 31793453 Pathogen - hypothetical protein Mb2297c 1 None None None 31793872 Common - POSSIBLE SECRETED ALANINE RICH PROTEIN Mb2719 4 None None None 31794100 Common - hypothetical protein Mb2948c 8 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 31792369 Common fadH PROBABLE NADPH DEPENDENT 2,4-DIENOYL-COA REDUCTASE FADH (2,4-dienoyl coenzyme A reductase) (4-enoyl-CoA reductase) Mb1208c 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 31794675 Common mce4A MCE-FAMILY PROTEIN MCE4A Mb3529c 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31793245 Common cobN cobaltochelatase Mb2088c 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 31793465 Common yjcE Probable conserved integral membrane transport protein YjcE Mb2309 91 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 31794520 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb3368c 29 COG1295 Rbn, Predicted membrane protein Function unknown 31792041 Common pdc PROBABLE PYRUVATE OR INDOLE-3-PYRUVATE DECARBOXYLASE PDC Mb0876c 218 COG3961 COG3961, Pyruvate decarboxylase and related thiamine pyrophosphate-requiring enzymes Carbohydrate transport and metabolism / Coenzyme metabolism / General function prediction only 31794970 Common fadE35 PROBABLE ACYL-COA DEHYDROGENASE FADE35 Mb3826 155 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31792381 Common - PROBABLE PROLINE DEHYDROGENASE Mb1220 118 COG0506 PutA, Proline dehydrogenase Amino acid transport and metabolism 31792896 Common - hypothetical protein Mb1736 124 COG1354 COG1354, Uncharacterized conserved protein Function unknown 31791454 Common - hypothetical protein Mb0282 15 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 31792827 Common lysS lysyl-tRNA synthetase Mb1667c 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 31793882 Common sigB RNA polymerase sigma factor SigB Mb2729 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 31793103 Common - PROBABLE EXPORTED PROTEIN Mb1945c 108 COG1881 COG1881, Phospholipid-binding protein General function prediction only 31794326 Common nuoF PROBABLE NADH DEHYDROGENASE I (CHAIN F) NUOF (NADH-UBIQUINONE OXIDOREDUCTASE CHAIN F) Mb3174 162 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 31792904 Common - hypothetical protein Mb1744 90 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 31793765 Common - POSSIBLE GLYOXALASE II (HYDROXYACYLGLUTATHIONE HYDROLASE) (GLX II) Mb2612c 219 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 31793789 Common - hypothetical protein Mb2636c 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 31793008 Pathogen PE_PGRS33 PE-PGRS FAMILY PROTEIN Mb1849c 1 None None None 31792240 Common - PROBABLE TRANSCRIPTIONAL REPRESSOR PROTEIN Mb1078 51 COG1846 MarR, Transcriptional regulators Transcription 31792808 Common cydB Probable integral membrane cytochrome D ubiquinol oxidase (subunit II) cydB (Cytochrome BD-I oxidase subunit II) Mb1648c 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 31794783 Common folB PROBABLE DIHYDRONEOPTERIN ALDOLASE FOLB (DHNA) Mb3637c 125 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 31794979 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3835c 5 None None None 31792945 Common - POSSIBLE SULFITE OXIDASE Mb1786 108 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 31791455 Common - hypothetical protein Mb0283c 4 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31793027 Common glcB malate synthase G Mb1868c 72 COG2225 AceB, Malate synthase Energy production and conversion 31791437 Common - hypothetical protein Mb0265c 16 COG2138 COG2138, Uncharacterized conserved protein Function unknown 31792088 Pathogen - POSSIBLE MEMBRANE PROTEIN Mb0924 1 None None None 31793226 Common pncA PYRAZINAMIDASE/NICOTINAMIDAS PNCA (PZase) Mb2069c 122 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 31794700 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb3554 19 COG3391 COG3391, Uncharacterized conserved protein Function unknown 31792292 Common glpX fructose 1,6-bisphosphatase II Mb1129c 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 31792538 Common - hypothetical protein Mb1377c 17 None None None 31793793 Common PPE42 PPE FAMILY PROTEIN Mb2640 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794071 Common viuB POSSIBLE MYCOBACTIN UTILIZATION PROTEIN VIUB Mb2919c 48 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 31793805 Common - hypothetical protein Mb2652c 13 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 31793990 Common - PROBABLE TRANSPOSASE Mb2838c 143 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 31794268 Common fadD13 PROBABLE CHAIN-FATTY-ACID-CoA LIGASE FADD13 (FATTY-ACYL-CoA SYNTHETASE) Mb3116 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793081 Common - hypothetical protein Mb1922c 5 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31791531 Common hspR PROBABLE HEAT SHOCK PROTEIN TRANSCRIPTIONAL REGULATOR HSPR (MERR FAMILY) Mb0361 71 COG0789 SoxR, Predicted transcriptional regulators Transcription 31792360 Common lpqW PUTATIVE LIPOPROTEIN LPQW Mb1198 26 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 31793682 Common accD1 PROBABLE ACETYL-/PROPIONYL-COA CARBOXYLASE (BETA SUBUNIT) ACCD1 Mb2530c 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 31793754 Common - PROBABLE TRANSMEMBRANE ALANINE AND VALINE AND LEUCINE RICH PROTEIN Mb2601c 10 COG4129 COG4129, Predicted membrane protein Function unknown 31794076 Common fdhF POSSIBLE FORMATE DEHYDROGENASE H FDHF (FORMATE-HYDROGEN-LYASE-LINKED, SELENOCYSTEINE-CONTAINING POLYPEPTIDE) (FORMATE DEHYDROGENASE-H ALPHA SUBUNIT) (FDH-H) Mb2924c 171 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 31793004 Common - hypothetical protein Mb1845 2 None None None 31793199 Common - hypothetical protein Mb2042 2 None None None 31794841 Common - PUTATIVE MEMBRANE-ASSOCIATED SERINE PROTEASE Mb3695c 157 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 31791699 Common - POSSIBLE MEMBRANE ACYLTRANSFERASE Mb0530 75 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 31794705 Common - hypothetical protein Mb3559c 18 None None None 31791372 Common - PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER Mb0200 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 31792401 Common - hypothetical protein Mb1240 78 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 31792886 Common - hypothetical protein Mb1726 143 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 31793032 Common - hypothetical protein Mb1873c 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 31791423 Common - PUTATIVE OXIDOREDUCTASE Mb0251 86 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 31794713 Common - 3-ketosteroid-delta-1-dehydrogenase Mb3567 64 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 31793879 Common - PROBABLE CONSERVED TRANSMEMBRANE ALANINE AND LEUCINE RICH PROTEIN Mb2726 9 COG1295 Rbn, Predicted membrane protein Function unknown 31794452 Common - hypothetical protein Mb3300 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 31792004 Common thiX PROBABLE THIOREDOXIN THIX Mb0839c 44 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 31795051 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3907 3 None None None 31791503 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY ARSR-FAMILY) Mb0332 113 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 31793564 Common - hypothetical protein Mb2408 33 COG3329 COG3329, Predicted permease General function prediction only 31792234 Common - hypothetical protein Mb1072c 32 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 31795086 Common trxB2 PROBABLE THIOREDOXIN REDUCTASE TRXB2 (TRXR) (TR) Mb3944 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 31792342 Common - hypothetical protein Mb1179c 7 None None None 31791571 Pathogen - hypothetical protein Mb0401 1 None None None 31792379 Common - hypothetical protein Mb1218c 19 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 31791194 Common rodA PROBABLE CELL DIVISION PROTEIN RODA Mb0017c 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 31794641 Common rmlC PROBABLE DTDP-4-DEHYDRORHAMNOSE 3,5-EPIMERASE RMLC (DTDP-4-KETO-6-DEOXYGLUCOSE 3,5-EPIMERASE) (DTDP-L-RHAMNOSE SYNTHETASE) (THYMIDINE DIPHOSPHO-4-KETORHAMNOSE 3,5-EPIMERASE) Mb3494 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 31791843 Common - hypothetical protein Mb0678c 1 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 31795020 Common sodA SUPEROXIDE DISMUTASE [FE] SODA Mb3876 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 31794030 Pathogen PE_PGRS48 PE-PGRS FAMILY PROTEIN Mb2878 1 None None None 31792023 Pathogen lpqQ POSSIBLE LIPOPROTEIN LPQQ Mb0858 1 None None None 31795036 Common whiB6 PUTATIVE TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB6 Mb3892c 1 None None None 31792395 Common dapE dipeptidase Mb1234 183 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 31791924 Common - hypothetical protein Mb0759 9 None None None 31794464 Common - hypothetical protein Mb3312 45 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 31791634 Common echA2 enoyl-CoA hydratase Mb0464c 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31791943 Common - PUTATIVE TRANSPOSASE (FRAGMENT) Mb0778c 2 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 31794203 Common iscS PROBABLE CYSTEINE DESULFURASE ISCS (NIFS PROTEIN HOMOLOG) (NITROGENASE METALLOCLUSTERS BIOSYNTHESIS PROTEIN NIFS) Mb3051c 235 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 31792814 Common - hypothetical protein Mb1654c 8 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 31793155 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1998c 66 COG1309 AcrR, Transcriptional regulator Transcription 31793198 Common - hypothetical protein Mb2041 6 COG2442 COG2442, Uncharacterized conserved protein Function unknown 31793321 Common - hypothetical protein Mb2165c 182 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 31794931 Common fadE36 POSSIBLE ACYL-COA DEHYDROGENASE FADE36 Mb3787c 57 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 31791569 Common - CONSERVED 13E12 REPEAT FAMILY PROTEIN Mb0399 5 None None None 31793640 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN Mb2486 213 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31794666 Common otsA PROBABLE ALPHA, ALPHA-TREHALOSE-PHOSPHATE SYNTHASE [UDP-FORMING] OTSA (TREHALOSE-6-PHOSPHATE SYNTHASE) (UDP-GLUCOSE-GLUCOSEPHOSPHATE GLUCOSYLTRANSFERASE) (TREHALOSEPHOSPHATE-UDP GLUCOSYLTRANSFERASE) (TREHALOSE-6-PHOSPHATE SYNTHETASE) (TREHALOSE-PHOSPHATE Mb3520 96 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 31791584 Common - BETA LACTAMASE LIKE PROTEIN Mb0414c 65 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 31794323 Common nuoC NADH dehydrogenase subunit C Mb3171 175 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 31794724 Common - short chain dehydrogenase Mb3578c 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31794953 Common - hypothetical protein Mb3809 12 None None None 31794647 Common - hypothetical protein Mb3500c 23 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 31791967 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb0802c 5 None None None 31793778 Common ruvC Holliday junction resolvase Mb2625c 190 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 31794691 Common echA19 enoyl-CoA hydratase Mb3545 182 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31794815 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3669 90 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31792647 Common - POSSIBLE TRANSCRIPTIONAL ACTIVATOR PROTEIN Mb1488 14 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 31791245 Common - short chain dehydrogenase Mb0069 123 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31791241 Common - hypothetical protein Mb0065 48 COG1615 COG1615, Uncharacterized conserved protein Function unknown 31792121 Pathogen pstBa PHOSPHATE-TRANSPORT PROTEIN ABC TRANSPORTER PSTBa [FIRST PART] Mb0957 1 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 31791234 Pathogen - hypothetical protein Mb0058 1 None None None 31793680 Common fadE19 POSSIBLE ACYL-COA DEHYDROGENASE FADE19 (MMGC) Mb2528c 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31794808 Common - transposase Mb3662 94 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 31794948 Common lipE PUTATIVE LIPASE LIPE Mb3804 97 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 31794973 Common accD4 PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHAIN 4 ACCD4 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) Mb3829c 204 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 31794256 Common - POSSIBLE HYDROLASE Mb3104 42 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 31793997 Common - hypothetical protein Mb2845c 33 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 31794331 Common nuoK NADH dehydrogenase subunit K Mb3179 162 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 31793984 Pathogen - hypothetical protein Mb2831 1 None None None 31794827 Common - POSSIBLE CONSERVED ALANINE RICH MEMBRANE PROTEIN Mb3681c 5 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 31792406 Common glgC glucose-1-phosphate adenylyltransferase Mb1245 164 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 31794384 Common - hypothetical protein Mb3232c 9 None None None 31793859 Common - PROBABLE ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE LEUCINE AND VALINE RICH PROTEIN ABC TRANSPORTER Mb2706c 7 None None None 31794392 Common gpm2 POSSIBLE PHOSPHOGLYCERATE MUTASE GPM2 (PHOSPHOGLYCEROMUTASE) (PGAM) (BPG-DEPENDENT PGAM) Mb3240 69 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 161511529 Common fadD29 acyl-CoA synthetase Mb2974c 208 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793649 Common - hypothetical protein Mb2495c 7 None None None 31794651 Pathogen PE31 PE FAMILY PROTEIN Mb3504 1 None None None 31792175 Common mscL large-conductance mechanosensitive channel Mb1011c 142 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 31791629 Common mmpS4 PROBABLE CONSERVED MEMBRANE PROTEIN MMPS4 Mb0459c 1 None None None 31794735 Common - short chain dehydrogenase Mb3589c 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31793522 Common moeW hypothetical protein Mb2366c 125 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 31793722 Common aroF chorismate synthase Mb2569c 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 31793532 Pathogen PPE71 PPE FAMILY PROTEIN Mb2376c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792077 Common citA citrate synthase 2 Mb0913c 192 COG0372 GltA, Citrate synthase Energy production and conversion 31792521 Pathogen PE_PGRS24 PE-PGRS FAMILY PROTEIN Mb1360c 1 None None None 31793850 Common hemE uroporphyrinogen decarboxylase Mb2697c 175 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 31791538 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb0368 3 None None None 31792790 Common impA PROBABLE INOSITOL-MONOPHOSPHATASE IMPA (IMP) Mb1630 177 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 31792433 Common mdh malate dehydrogenase Mb1272 88 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 31793188 Common - hypothetical protein Mb2031c 41 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 31794652 Common PPE60 PE FAMILY PROTEIN Mb3505 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791893 Common rplP 50S ribosomal protein L16 Mb0728 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 31793934 Pathogen - hypothetical protein Mb2781c 1 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 31794438 Common - hypothetical protein Mb3286c 18 None None None 31794680 Common fadE26 PROBABLE ACYL-COA DEHYDROGENASE FADE26 Mb3534 152 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31794864 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb3718 85 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 31791279 Common nrp PROBABLE PEPTIDE SYNTHETASE NRP (PEPTIDE SYNTHASE) Mb0104 214 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31793693 Pathogen - hypothetical protein Mb2541 1 None None None 31793232 Common - hypothetical protein Mb2075c 1 None None None 31794984 Common pirG EXPORTED REPETITIVE PROTEIN PRECURSOR PIRG (CELL SURFACE PROTEIN) (EXP53) Mb3840 1 None None None 31793586 Common - ribonuclease Z Mb2430 99 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 31793554 Common mbtH PUTATIVE CONSERVED PROTEIN MBTH Mb2398c 37 COG3251 COG3251, Uncharacterized protein conserved in bacteria Function unknown 31793518 Common cysK1 PROBABLE CYSTEINE SYNTHASE A CYSK1 (O-ACETYLSERINE SULFHYDRYLASE A) (O-ACETYLSERINE (THIOL)-LYASE A) (CSASE A) Mb2362 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 31792019 Pathogen - hypothetical protein Mb0854c 2 None None None 31792588 Common cyp132 PROBABLE CYTOCHROME P450 132 CYP132 Mb1429c 69 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31791787 Common - POSSIBLE RESOLVASE Mb0621 21 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 31794117 Common mas PROBABLE MULTIFUNCTIONAL MYCOCEROSIC ACID SYNTHASE MEMBRANE-ASSOCIATED MAS Mb2965c 224 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31792422 Common mrp PROBABLE MRP-RELATED PROTEIN MRP Mb1261c 231 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 31792001 Common - hypothetical protein Mb0836c 14 None None None 31793702 Common bcp PROBABLE BACTERIOFERRITIN COMIGRATORY PROTEIN BCP Mb2550 218 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 31793405 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase Mb2249 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 31794658 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb3512c 4 None None None 31793836 Pathogen - hypothetical protein Mb2683c 1 None None None 31792445 Common lprE PROBABLE LIPOPROTEIN LPRE Mb1284c 1 None None None 31794089 Common - POSSIBLE D-AMINO ACID AMINOHYDROLASE Mb2937c 59 COG3653 COG3653, N-acyl-D-aspartate/D-glutamate deacylase Secondary metabolites biosynthesis, transport, and catabolism 31793877 Common - hypothetical protein Mb2724c 42 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 31794427 Common tmk thymidylate kinase Mb3275c 55 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 31794261 Common virS VIRULENCE-REGULATING TRANSCRIPTIONAL REGULATOR VIRS (ARAC/XYLS FAMILY) Mb3109c 66 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 31792889 Common - Probable catechol-o-methyltransferase Mb1729c 48 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 31794898 Common - PUTATIVE DEHYDROGENASE Mb3753 175 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 31794843 Common - POSSIBLE MEMBRANE-ANCHORED THIOREDOXIN-LIKE PROTEIN (THIOL-DISULFIDE INTERCHANGE RELATED PROTEIN) Mb3697c 48 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 31791813 Common recC PROBABLE EXONUCLEASE V (GAMMA CHAIN) RECC (EXODEOXYRIBONUCLEASE V GAMMA CHAIN)(EXODEOXYRIBONUCLEASE V POLYPEPTIDE) Mb0648c 64 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 31794378 Common - PROBABLE ATP-DEPENDENT DNA HELICASE Mb3226c 201 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 31794404 Pathogen - hypothetical protein Mb3252 1 COG2606 EbsC, Uncharacterized conserved protein Function unknown 31794569 Common - POSSIBLE DEHYDROGENASE Mb3421c 25 COG2030 MaoC, Acyl dehydratase Lipid metabolism 31792119 Common pknDa TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE D PKNDa [FIRST PART] (PROTEIN KINASE D) (STPK D) Mb0955c 148 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 31792187 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb1023 5 None None None 31791314 Common cyp138 PROBABLE CYTOCHROME P450 138 CYP138 Mb0141 83 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31793331 Common ftsQ POSSIBLE CELL DIVISION PROTEIN FTSQ Mb2175c 27 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 31792932 Common - PROBABLE MEMBRANE PROTEIN Mb1773c 2 None None None 31793870 Common - PROBABLE CONSERVED ALANINE RICH TRANSMEMBRANE PROTEIN Mb2717 14 None None None 31794606 Common PPE57 PPE FAMILY PROTEIN Mb3459 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792130 Common - hypothetical protein Mb0966c 4 None None None 31792746 Common - hypothetical protein Mb1587 10 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31792250 Common - hypothetical protein Mb1088 20 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 31792537 Common - putative deoxyribonucleotide triphosphate pyrophosphatase Mb1376 233 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 31794627 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb3480c 8 None None None 31794769 Common TB11.2 hypothetical protein Mb3623 19 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 31791838 Common - PROBABLE DIOXYGENASE Mb0673 35 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 31792898 Common - hypothetical protein Mb1738 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 31791323 Common - hypothetical protein Mb0150 27 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31793844 Common - POSSIBLE SECRETED PROTEASE Mb2691 16 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31794613 Common glmS D-fructose-6-phosphate amidotransferase Mb3466c 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 31792687 Common - hypothetical protein Mb1528c 85 COG0398 COG0398, Uncharacterized conserved protein Function unknown 31794236 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb3084c 5 COG1309 AcrR, Transcriptional regulator Transcription 31793624 Common dctA PROBABLE C4-DICARBOXYLATE-TRANSPORT TRANSMEMBRANE PROTEIN DCTA Mb2470 144 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 31792754 Common bioA adenosylmethionine--8-amino-7-oxononanoate transaminase Mb1595 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 31793536 Common furB PROBABLE FERRIC UPTAKE REGULATION PROTEIN FURB Mb2380 188 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 31792705 Pathogen - hypothetical protein Mb1546 1 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 31793455 Common cyp121 Cytochrome P450 121 CYP121 Mb2299 67 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31792799 Common trpA tryptophan synthase subunit alpha Mb1639 214 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 31794245 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY DEOR-FAMILY) Mb3093 18 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 31793493 Common - POSSIBLE EXCISIONASE Mb2337 28 None None None 31791560 Common - POSSIBLE CONSERVED SECRETED PROTEIN Mb0390c 5 None None None 31791427 Common - PUTATIVE SUCCINATE DEHYDROGENASE [MEMBRANE ANCHOR SUBUNIT] (SUCCINIC DEHYDROGENASE) Mb0255c 10 None None None 31793729 Common - hypothetical protein Mb2576 3 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31793189 Pathogen - hypothetical protein Mb2032 1 COG5450 COG5450, Transcription regulator of the Arc/MetJ class Transcription 31792329 Common PPE16 PPE FAMILY PROTEIN Mb1166c 5 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794574 Common - hypothetical protein Mb3426c 27 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 31794544 Common - hypothetical protein Mb3396c 74 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 31793902 Pathogen - hypothetical protein Mb2749 1 None None None 31794531 Pathogen - PROBABLE TRANSPOSASE Mb3381 1 None None None 31791228 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0052 16 COG5650 COG5650, Predicted integral membrane protein Function unknown 31791603 Common ctpH POSSIBLE METAL CATION TRANSPORTING P-TYPE ATPASE CTPH Mb0433c 229 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 31794773 Common clpC PROBABLE ATP-DEPENDENT CLP PROTEASE ATP-BINDING SUBUNIT CLPC Mb3627c 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 31791217 Common mtc28 SECRETED PROLINE RICH PROTEIN MTC28 (PROLINE RICH 28 KDA ANTIGEN) Mb0041c 1 None None None 31794351 Common - short chain dehydrogenase Mb3199 223 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 31791914 Common serA2 POSSIBLE D-3-PHOSPHOGLYCERATE DEHYDROGENASE SERA2 (PHOSPHOGLYCERATE DEHYDROGENASE) (PGDH) Mb0749c 229 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 31791212 Common fadD34 PROBABLE FATTY-ACID-COA LIGASE FADD34 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-COA SYNTHASE) Mb0036 194 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792920 Common - hypothetical protein Mb1761c 68 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 31794056 Common - hypothetical protein Mb2904c 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 31793714 Pathogen - hypothetical protein Mb2561c 1 None None None 31793419 Common - hypothetical protein Mb2263c 16 None None None 31791251 Common - hypothetical protein Mb0076 67 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 31793473 Common - hypothetical protein Mb2317 12 COG3196 COG3196, Uncharacterized protein conserved in bacteria Function unknown 31794393 Common entC isochorismate synthase Mb3241 223 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 161511531 Common aroE shikimate 5-dehydrogenase Mb2582c 170 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 31792713 Common pks5 Probable polyketide synthase pks5 Mb1554c 212 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794787 Common - HYPOTHETICAL ARGININE AND PROLINE RICH PROTEIN Mb3641 13 None None None 31792733 Common dnaE DNA polymerase III subunit alpha Mb1574 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 31791477 Common - hypothetical protein Mb0306 1 None None None 31795017 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3873c 3 None None None 31794777 Common panD aspartate alpha-decarboxylase Mb3631c 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 31791954 Common cyp123 PROBABLE CYTOCHROME P450 123 CYP123 Mb0789c 75 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31792620 Common lipO PROBABLE ESTERASE LIPO Mb1461c 116 COG0657 Aes, Esterase/lipase Lipid metabolism 31792951 Pathogen - hypothetical protein Mb1792c 1 None None None 31792999 Pathogen - hypothetical protein Mb1840 1 None None None 31793111 Common - hypothetical protein Mb1954c 3 None None None 31791417 Pathogen - hypothetical protein Mb0245 1 None None None 31793289 Common prcA proteasome (alpha subunit) PrcA Mb2133c 17 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 31791379 Common - hypothetical protein Mb0207c 1 None None None 31792568 Pathogen - hypothetical protein Mb1409c 1 None None None 31793377 Common mmpS3 PROBABLE CONSERVED MEMBRANE PROTEIN MMPS3 Mb2221c 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 31791643 Common - hypothetical protein Mb0473c 10 COG2128 COG2128, Uncharacterized conserved protein Function unknown 31794063 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb2911 18 COG1846 MarR, Transcriptional regulators Transcription 31793018 Common - hypothetical protein Mb1859 18 COG0789 SoxR, Predicted transcriptional regulators Transcription 31793860 Common - PROBABLE ANTIBIOTIC-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER Mb2707c 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 31792577 Common carA carbamoyl phosphate synthase small subunit Mb1418 236 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 31795044 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb3900 194 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 31793380 Common asnB Probable asparagine synthetase AsnB Mb2224 154 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 31794993 Common - hypothetical protein Mb3849 2 None None None 31791185 Common - POSSIBLE MEMBRANE PROTEIN Mb0008c 1 None None None 31794099 Common acyP PROBABLE ACYLPHOSPHATASE ACYP (ACYLPHOSPHATE PHOSPHOHYDROLASE) Mb2947c 71 COG1254 AcyP, Acylphosphatases Energy production and conversion 31794473 Common pcd PROBABLE PIPERIDEINE-6-CARBOXILIC ACID DEHYDROGENASE PCD (PIPERIDEINE-6-CARBOXYLATE DEHYDROGENASE) Mb3321 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 31794927 Common proW POSSIBLE OSMOPROTECTANT (GLYCINE BETAINE/CARNITINE/CHOLINE/L-PROLINE) TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER PROW Mb3783c 104 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 31793421 Common aceE pyruvate dehydrogenase subunit E1 Mb2265 144 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 31791552 Common - PROBABLE CARBON MONOXYDE DEHYDROGENASE (MEDIUM CHAIN) Mb0382c 100 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 31792505 Common - CONSERVED HYPOTHETICAL SECRETED PROTEIN Mb1344 9 None None None 31791400 Common - PROBABLE ALDEHYDE DEHYDROGENASE Mb0228c 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 31794577 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Mb3429c 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 31795039 Pathogen - hypothetical protein Mb3895 1 None None None 31791554 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LYSR-FAMILY) Mb0384 119 COG0583 LysR, Transcriptional regulator Transcription 31793136 Common - hypothetical protein Mb1979c 2 None None None 31793030 Pathogen PE_PGRS34 PE-PGRS FAMILY PROTEIN Mb1871c 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 31793957 Common - POSSIBLE ALANINE RICH OXIDOREDUCTASE Mb2804c 135 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 31793270 Common - hypothetical protein Mb2114 8 None None None 31792870 Common - hypothetical protein Mb1710A 29 COG2835 COG2835, Uncharacterized conserved protein Function unknown 31794519 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY MERR-FAMILY) Mb3367 143 COG0789 SoxR, Predicted transcriptional regulators Transcription 31792846 Common argH argininosuccinate lyase Mb1687 216 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 31793358 Common - Probable conserved integral membrane protein Mb2202c 7 None None None 31793543 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2387c 218 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 31792877 Common - hypothetical protein Mb1717 18 None None None 31793292 Common - hypothetical protein Mb2136c 16 None None None 31794637 Common rpmJ 50S ribosomal protein L36 Mb3490c 132 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 31794131 Common - hypothetical protein Mb2979c 63 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 31792152 Common - hypothetical protein Mb0988c 8 None None None 31791615 Common psd phosphatidylserine decarboxylase Mb0445c 92 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 31792663 Common ctpD PROBABLE CATION TRANSPORTER P-TYPE ATPASE D CTPD Mb1504 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 31795063 Pathogen esxC PUTATIVE ESAT-6 LIKE PROTEIN 11 Mb3919c 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31795091 Common parA PROBABLE CHROMOSOME PARTITIONING PROTEIN PARA Mb3949c 230 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 31794194 Common esxQ PUTATIVE ESAT-6 LIKE PROTEIN 8 Mb3042c 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31791264 Common hycQ POSSIBLE HYDROGENASE HYCQ Mb0089 167 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 31792058 Common - hypothetical protein Mb0894c 42 COG3304 COG3304, Predicted membrane protein Function unknown 31792872 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER Mb1712c 93 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 31792673 Common - HYPOTHETICAL INVASION PROTEIN Mb1514 129 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 31794876 Common - hypothetical protein Mb3731c 1 None None None 31792764 Common - Probable phiRv1 phage protein Mb1604c 25 COG3747 COG3747, Phage terminase, small subunit DNA replication, recombination, and repair 31791272 Common - hypothetical protein Mb0097c 7 None None None 31793594 Common - hypothetical protein Mb2438c 82 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 31794012 Common ugpAa PROBABLE Sn-GLYCEROL-3-PHOSPHATE TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER UGPAA [FIRST PART] Mb2860c 12 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 31794087 Common dacB2 PROBABLE D-ALANYL-D-ALANINE CARBOXYPEPTIDASE DACB2 (PENICILLIN-BINDING PROTEIN) (DD-PEPTIDASE) (DD-CARBOXYPEPTIDASE) (PBP) (DD-TRANSPEPTIDASE) (SERINE-TYPE D-ALA-D-ALA CARBOXYPEPTIDASE) Mb2935 149 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 31791547 Common - POSSIBLE OXIDOREDUCTASE Mb0377c 87 COG0714 COG0714, MoxR-like ATPases General function prediction only 31792101 Common - POSSIBLE DIOXYGENASE Mb0937c 35 COG3670 COG3670, Lignostilbene-alpha,beta-dioxygenase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 31792108 Common - PUTATIVE TRANSPOSASE Mb0944c 85 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 31792977 Common PPE26 PPE FAMILY PROTEIN Mb1817 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794702 Common - POSSIBLE OXIDOREDUCTASE Mb3556 69 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 31793216 Common - hypothetical protein Mb2059c 15 None None None 31791501 Common udgA PROBABLE UDP-GLUCOSE 6-DEHYDROGENASE UDGA (UDP-GLC DEHYDROGENASE) (UDP-GLCDH) (UDPGDH) Mb0330 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 31794217 Common echA17 enoyl-CoA hydratase Mb3065c 164 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31792927 Common - PROBABLE SULPHATE-TRANSPORT TRANSMEMBRANE PROTEIN ABC TRANSPORTER Mb1768c 158 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 31791654 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0484 33 COG1396 HipB, Predicted transcriptional regulators Transcription 31791682 Common - hypothetical protein Mb0512 18 None None None 31794380 Common lipV POSSIBLE LIPASE LIPV Mb3228 20 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31793435 Pathogen - hypothetical protein Mb2279c 1 None None None 31793389 Common ilvE branched-chain amino acid aminotransferase Mb2233c 198 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 31792166 Pathogen PE_PGRS16 PE-PGRS FAMILY PROTEIN Mb1002 1 COG5281 COG5281, Phage-related minor tail protein Function unknown 31792665 Common trxB1 PROBABLE THIOREDOXIN TRXB1 Mb1506 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 31793243 Common - Possible conserved integral membrane protein Mb2086 15 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 31793175 Common - hypothetical protein Mb2018 15 COG3945 COG3945, Uncharacterized conserved protein Function unknown 31792032 Common narL POSSIBLE NITRATE/NITRITE RESPONSE TRANSCRIPTIONAL REGULATORY PROTEIN NARL Mb0867c 210 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 31791255 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0080 78 COG1309 AcrR, Transcriptional regulator Transcription 31794185 Pathogen - hypothetical protein Mb3033 1 COG1285 SapB, Uncharacterized membrane protein Function unknown 31792869 Common - acyl-CoA synthetase Mb1710 78 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 31791369 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0197 106 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31791462 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb0291 8 None None None 31792014 Common - hypothetical protein Mb0849 22 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 31794760 Common - PUTATIVE TRANSCRIPTION FACTOR Mb3614c 84 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 31794592 Common guaB2 inositol-5-monophosphate dehydrogenase Mb3445c 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 31794481 Common phoY1 PROBABLE PHOSPHATE-TRANSPORT SYSTEM TRANSCRIPTIONAL REGULATORY PROTEIN PHOU HOMOLOG 1 PHOY1 Mb3329c 182 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 31794781 Common - PROBABLE CONSERVED SECRETED PROTEIN Mb3635c 5 None None None 31791677 Common - hypothetical protein Mb0507 178 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 31794312 Pathogen PPE51 PPE FAMILY PROTEIN Mb3160 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791805 Common - hypothetical protein Mb0639 5 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 31794851 Common - PROBABLE ANION TRANSPORTER ATPASE Mb3705 22 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 31792192 Common arcA arginine deiminase Mb1028 52 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 31792692 Common - arginine/ornithine transport system ATPase Mb1533 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 31794688 Common fadD18 PROBABLE FATTY-ACID-COA LIGASE FADD18 (FRAGMENT) (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-COA SYNTHASE) Mb3542c 207 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792284 Pathogen PE_PGRS22 PE-PGRS FAMILY PROTEIN Mb1121 1 COG5164 SPT5, Transcription elongation factor Transcription 31791989 Common - hypothetical protein Mb0824 14 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 31792472 Common oppA PROBABLE PERIPLASMIC OLIGOPEPTIDE-BINDING LIPOPROTEIN OPPA Mb1311c 156 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 31791203 Common - hypothetical protein Mb0027 1 None None None 31791676 Common - hypothetical protein Mb0506c 9 None None None 31793207 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb2050c 218 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 31794674 Common mce4B MCE-FAMILY PROTEIN MCE4B Mb3528c 18 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31792523 Common glgE PROBABLE GLUCANASE GLGE Mb1362c 99 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 31791396 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0224 55 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 31791764 Common - hypothetical protein Mb0597 6 COG2402 COG2402, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794107 Common fadD26 acyl-CoA synthetase Mb2955 207 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792290 Pathogen - PROBABLE MEMBRANE GLYCINE AND PROLINE RICH PROTEIN Mb1127c 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 31791348 Common mce1B MCE-FAMILY PROTEIN MCE1B Mb0176 58 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31791785 Pathogen - POSSIBLE EXPORTED PROTEIN Mb0619 1 None None None 31794163 Common leuD isopropylmalate isomerase small subunit Mb3011c 205 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 31792549 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1388c 25 COG1309 AcrR, Transcriptional regulator Transcription 31793317 Common - hypothetical protein Mb2161c 3 None None None 31791859 Common echA5 enoyl-CoA hydratase Mb0694 178 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31791728 Common - hypothetical protein Mb0560c 13 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 31793538 Common - LONG (C50) CHAIN Z-ISOPRENYL DIPHOSPHATE SYNTHASE (Z-DECAPRENYL DIPHOSPHATE SYNTHASE) Mb2382c 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 31792479 Common - hypothetical protein Mb1318 173 COG1959 COG1959, Predicted transcriptional regulator Transcription 31794503 Common - POSSIBLE METHYLTRANSFERASE Mb3351c 17 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 31794146 Common lipN PROBABLE LIPASE/ESTERASE LIPN Mb2994c 117 COG0657 Aes, Esterase/lipase Lipid metabolism 31793354 Common pknL PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE L PKNL (PROTEIN KINASE L) (STPK L) Mb2198 143 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 31793636 Common - PROBABLE OXIDOREDUCTASE (ALPHA SUBUNIT) Mb2482c 107 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 31792274 Common - hypothetical protein Mb1112 3 None None None 31792824 Common uvrA excinuclease ABC subunit A Mb1664 233 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 31792622 Common - hypothetical protein Mb1463c 25 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 31793367 Common - hypothetical protein Mb2211c 220 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 31794043 Common - hypothetical protein Mb2891 22 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 31791758 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY ARSR-FAMILY) Mb0591 107 COG3832 COG3832, Uncharacterized conserved protein Function unknown 31792417 Common tatB sec-independent translocase Mb1256 8 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 31791425 Common - fumarate reductase iron-sulfur subunit Mb0253c 205 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 31794555 Common otsB2 POSSIBLE TREHALOSE 6-PHOSPHATE PHOSPHATASE OTSB2 (TREHALOSE-PHOSPHATASE) (TPP) Mb3407 92 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 31791823 Common nusG transcription antitermination protein NusG Mb0658 215 COG0250 NusG, Transcription antiterminator Transcription 31793710 Common - hypothetical protein Mb2558 7 COG1948 MUS81, ERCC4-type nuclease DNA replication, recombination, and repair 31791696 Common - POSSIBLE TRANSMEMBRANE PROTEIN Mb0527 1 None None None 31794028 Common - hypothetical protein Mb2876c 76 COG2153 ElaA, Predicted acyltransferase General function prediction only 31792227 Common - PROBABLE TRANSPOSASE (FRAGMENT) Mb1064c 3 None None None 31794090 Common pknI PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE I PKNI (PROTEIN KINASE I) (STPK I) (PHOSPHORYLASE B KINASE KINASE) (HYDROXYALKYL-PROTEIN KINASE) Mb2938c 143 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 31791573 Common - CONSERVED 13E12 REPEAT FAMILY PROTEIN Mb0403 1 None None None 31791487 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0316 33 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 31793867 Common - CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN Mb2714 3 None None None 31792805 Common - hypothetical protein Mb1645 44 COG2898 COG2898, Uncharacterized conserved protein Function unknown 31791353 Common - PROBABLE CONSERVED MCE ASSOCIATED MEMBRANE PROTEIN Mb0181 2 None None None 31791514 Common - CONSERVED 13E12 REPEAT FAMILY PROTEIN Mb0343 6 None None None 31791520 Common iniA ISONIAZID INDUCTIBLE GENE PROTEIN INIA Mb0349 20 COG0699 COG0699, Predicted GTPases (dynamin-related) General function prediction only 31792677 Common - hypothetical protein Mb1518c 8 None None None 31793973 Common - hypothetical protein Mb2820c 9 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 31794858 Common - hypothetical protein Mb3712c 2 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 31792485 Common argS arginyl-tRNA synthetase Mb1324 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31792617 Common whiA PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN WHIA Mb1458 37 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 31793349 Common lppM Probable conserved lipoprotein lppM Mb2193 4 None None None 31794067 Common - hypothetical protein Mb2915 24 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 31794082 Common trmD tRNA (guanine-N(1)-)-methyltransferase Mb2930c 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 31794836 Common dppA PROBABLE PERIPLASMIC DIPEPTIDE-BINDING LIPOPROTEIN DPPA Mb3690c 161 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 31791374 Common - PUTATIVE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0202 49 COG1309 AcrR, Transcriptional regulator Transcription 31792542 Common fadE14 POSSIBLE ACYL-COA DEHYDROGENASE FADE14 Mb1381 127 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31794385 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb3233 127 COG1309 AcrR, Transcriptional regulator Transcription 31791982 Common - hypothetical protein Mb0817 7 COG1359 COG1359, Uncharacterized conserved protein Function unknown 31792980 Pathogen esxM hypothetical protein Mb1820 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31791628 Common mmpL4 PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL4 Mb0458c 49 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31794132 Common - hypothetical protein Mb2980 28 None None None 31795054 Common - hypothetical protein Mb3910c 1 None None None 31792656 Common - hypothetical protein Mb1497 167 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 31792955 Common - hypothetical protein Mb1795A 69 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 31792776 Common - hypothetical protein Mb1616 7 None None None 31791295 Common oxyS OXIDATIVE STRESS RESPONSE REGULATORY PROTEIN OXYS Mb0121 183 COG0583 LysR, Transcriptional regulator Transcription 31794222 Common fecB PROBABLE FEIII-DICITRATE-BINDING PERIPLASMIC LIPOPROTEIN FECB Mb3070 53 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 31794514 Common - hypothetical protein Mb3362 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 31792670 Common acn aconitate hydratase Mb1511c 222 COG1048 AcnA, Aconitase A Energy production and conversion 31792787 Common hisB imidazoleglycerol-phosphate dehydratase Mb1627 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 31793257 Common - Possible hypothetical exported or envelope protein Mb2100c 3 None None None 31793069 Common glnA3 PROBABLE GLUTAMINE SYNTHETASE GLNA3 (GLUTAMINE SYNTHASE) (GS-I) Mb1910 222 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 31794361 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb3209 5 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 31791527 Pathogen - hypothetical protein Mb0357 2 None None None 31791680 Common - hypothetical protein Mb0510 7 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 31793896 Common fadE20 PROBABLE ACYL-CoA DEHYDROGENASE FADE20 Mb2743c 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31792901 Common - Probable oxidoreductase Mb1741 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31792297 Common - POSSIBLE PARA-NITROBENZYL ESTERASE (FRAGMENT) Mb1134 56 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 31792572 Common - hypothetical protein Mb1413c 5 None None None 31792651 Common - PROBABLE UNIDENTIFIED ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER Mb1492c 16 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 31793604 Common - PROBABLE TRANSPOSASE [FIRST PART] Mb2448c 18 None None None 31793931 Common - hypothetical protein Mb2778c 3 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794795 Common mesJ POSSIBLE CELL CYCLE PROTEIN MESJ Mb3649c 31 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 31791457 Pathogen PE_PGRS3 PE-PGRS FAMILY PROTEIN Mb0286c 1 None None None 31791329 Common PE1 PE FAMILY PROTEIN Mb0156c 1 None None None 31793916 Pathogen - CONSERVED HYPOTHETICAL ARGININE RICH PROTEIN [FIRST PART] Mb2763c 1 None None None 31791670 Common senX3 PUTATIVE TWO COMPONENT SENSOR HISTIDINE KINASE SENX3 Mb0500 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 31793094 Common cinA competence damage-inducible protein A Mb1936 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 31793752 Common - hypothetical protein Mb2599c 82 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 31793816 Common - hypothetical protein Mb2663 2 COG1371 COG1371, Uncharacterized conserved protein Function unknown 31794152 Common ung uracil-DNA glycosylase Mb3000c 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 31792819 Common uvrB excinuclease ABC subunit B Mb1659 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 31791747 Common - PROBABLE MONOOXYGENASE Mb0580c 64 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 31792315 Common zwf1 glucose-6-phosphate 1-dehydrogenase Mb1152 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 31791497 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0326c 12 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 31792636 Common bisC PROBABLE BIOTIN SULFOXIDE REDUCTASE BISC (BDS reductase) (BSO reductase) Mb1477 151 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 31792136 Common - PROBABLE MYCOLYL TRANSFERASE Mb0972c 1 None None None 31793062 Common lldD2 POSSIBLE L-LACTATE DEHYDROGENASE (CYTOCHROME) LLDD2 Mb1903c 111 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 31792780 Common nadA quinolinate synthetase Mb1620 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 31791669 Common gpm1 phosphoglyceromutase Mb0499 157 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 31793280 Common - hypothetical protein Mb2124c 16 None None None 31792278 Pathogen PE_PGRS21 PE-PGRS FAMILY PROTEIN Mb1116 1 None None None 31793549 Common - hypothetical protein Mb2393c 37 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 31794343 Common - hypothetical protein Mb3191c 4 None None None 31792351 Pathogen - CONSERVED HYPOTHETICAL ALA-, PRO-RICH PROTEIN Mb1189c 1 None None None 31793272 Common pepE Probable dipeptidase PepE Mb2116c 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 31792051 Common - hypothetical protein Mb0886 4 None None None 31793947 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2794c 10 None None None 31794690 Common fadD19 acyl-CoA synthetase Mb3544c 218 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792147 Common - POSSIBLE MAGNESIUM CHELATASE Mb0983 53 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 31793911 Common - hypothetical protein Mb2758c 14 None None None 31794037 Common glnA4 PROBABLE GLUTAMINE SYNTHETASE GLNA4 (GLUTAMINE SYNTHASE) (GS-II) Mb2885c 221 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 31794151 Common - CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN Mb2999c 18 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 31794826 Common - hypothetical protein Mb3680c 3 None None None 31791598 Common - POSSIBLE TRANSMEMBRANE PROTEIN Mb0428c 1 None None None 31794333 Common nuoM NADH dehydrogenase subunit M Mb3181 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 31791490 Common - hypothetical protein Mb0319 3 None None None 31793224 Common - Probable sugar-binding lipoprotein Mb2067c 98 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 31791753 Common - hypothetical protein Mb0586c 69 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 31791432 Common cobU PUTATIVE BIFUNCTIONAL COBALAMIN BIOSYNTHESIS PROTEIN COBU: COBINAMIDE KINASE + COBINAMIDE PHOSPHATE GUANYLYLTRANSFERASE Mb0260c 128 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 31793767 Common relA PROBABLE GTP PYROPHOSPHOKINASE RELA (ATP:GTP 3'-PYROPHOSPHOTRANSFERASE) (PPGPP SYNTHETASE I) ((P)PPGPP SYNTHETASE) (GTP DIPHOSPHOKINASE) Mb2614c 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 31793029 Pathogen - hypothetical protein Mb1870c 1 None None None 31792858 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN Mb1699c 114 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 31792339 Common - PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE Mb1176 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31791664 Common - PUTATIVE SHORT-CHAIN TYPE OXIDOREDUCTASE Mb0494c 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 31791772 Common mce2B MCE-FAMILY PROTEIN MCE2B Mb0605 7 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31793665 Common echA14 enoyl-CoA hydratase Mb2511 171 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31792469 Common - hypothetical protein Mb1308 57 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 31793002 Pathogen - hypothetical protein Mb1843c 2 None None None 31794534 Common - hypothetical protein Mb3386c 4 None None None 31793800 Pathogen - hypothetical protein Mb2647 1 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 31791505 Common cyp135A1 POSSIBLE CYTOCHROME P450 135A1 CYP135A1 Mb0334c 88 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31791811 Common recD PROBABLE EXONUCLEASE V (ALPHA CHAIN) RECD (EXODEOXYRIBONUCLEASE V ALPHA CHAIN) (EXODEOXYRIBONUCLEASE V POLYPEPTIDE) Mb0645c 126 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 31794078 Common rnhB ribonuclease HII Mb2926c 213 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 31794048 Common - hypothetical protein Mb2896 2 COG4710 COG4710, Predicted DNA-binding protein with an HTH domain General function prediction only 31794910 Common - hypothetical protein Mb3766c 28 None None None 31793557 Common mbtE PEPTIDE SYNTHETASE MBTE (PEPTIDE SYNTHASE) Mb2401c 211 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794982 Common - GALACTOFURANOSYL TRANSFERASE Mb3838c 22 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 31793006 Pathogen - hypothetical protein Mb1847 1 None None None 31791733 Common fadD8 acyl-CoA synthetase Mb0566c 222 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31794044 Common - hypothetical protein Mb2892c 14 COG3393 COG3393, Predicted acetyltransferase General function prediction only 31791875 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0710c 6 COG1309 AcrR, Transcriptional regulator Transcription 31794450 Common ctpC PROBABLE METAL CATION-TRANSPORTING P-TYPE ATPASE C CTPC Mb3298 230 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 31792362 Common PPE17a PPE FAMILY PROTEIN [FIRST PART] Mb1201c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791215 Common - hypothetical protein Mb0039 121 COG1678 COG1678, Putative transcriptional regulator Transcription 31794283 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb3131c 106 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 31794942 Common - PROBABLE REMNANT OF A TRANSPOSASE Mb3798c 2 None None None 31792110 Common - PUTATIVE TRANSPOSASE Mb0946 26 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 31792829 Common rpmI 50S ribosomal protein L35 Mb1669 127 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 31793166 Common - POSSIBLE CHITINASE Mb2009 12 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 31793928 Common thyX FAD-dependent thymidylate synthase Mb2775c 49 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 31792158 Common ctpV PROBABLE METAL CATION TRANSPORTER P-TYPE ATPASE CTPV Mb0994 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 31792510 Common ogt PROBABLE METHYLATED-DNA--PROTEIN-CYSTEINE METHYLTRANSFERASE OGT (6-O-methylguanine-DNA methyltransferase) (O-6-methylguanine-DNA-alkyltransferase) Mb1349c 219 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 31794622 Common esxU hypothetical protein Mb3475c 2 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31791364 Common bglS PROBABLE BETA-GLUCOSIDASE BGLS (GENTIOBIASE) (CELLOBIASE) (BETA-D-GLUCOSIDE GLUCOHYDROLASE) Mb0192 102 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 31791965 Common purB adenylosuccinate lyase Mb0800 181 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 31794707 Common - hypothetical protein Mb3561c 10 None None None 31794645 Common mhpE 4-hydroxy-2-ketovalerate aldolase Mb3498c 202 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 31791697 Common - CONSERVED 13E12 REPEAT FAMILY PROTEIN Mb0528 6 None None None 31793393 Common ephD short chain dehydrogenase Mb2237c 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 31792841 Common argB acetylglutamate kinase Mb1682 213 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 31791192 Common pknA TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE A PKNA (PROTEIN KINASE A) (STPK A) Mb0015c 155 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 31791862 Common - hypothetical protein Mb0697 7 COG1510 COG1510, Predicted transcriptional regulators Transcription 31793566 Common rpfD PROBABLE RESUSCITATION-PROMOTING FACTOR RPFD Mb2410c 12 None None None 31794093 Common - CONSERVED HYPOTHETICAL ALANINE AND ARGININE RICH PROTEIN Mb2941 27 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 31794831 Common - hypothetical protein Mb3685 81 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 31795053 Common - HYPOTHETICAL ALANINE AND PROLINE RICH PROTEIN Mb3909c 1 COG3225 GldG, ABC-type uncharacterized transport system involved in gliding motility, auxiliary component Cell motility and secretion 31792605 Common lprG PROBABLE CONSERVED LIPOPROTEIN LPRG Mb1446c 5 None None None 31794243 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb3091c 29 COG2259 COG2259, Predicted membrane protein Function unknown 31791334 Common pntAb PROBABLE NAD(P) TRANSHYDROGENASE (SUBUNIT ALPHA) PNTAb [SECOND PART; INTEGRAL MEMBRANE PROTEIN] (PYRIDINE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA) (NICOTINAMIDE NUCLEOTIDE TRANSHYDROGENASE SUBUNIT ALPHA) Mb0161 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 31791257 Common - hypothetical protein Mb0082 3 None None None 31792943 Common plcD PROBABLE PHOSPHOLIPASE C 4 PLCD Mb1784c 33 COG3511 PlcC, Phospholipase C Cell envelope biogenesis, outer membrane 31794883 Common dnaQ DNA polymerase III subunit epsilon Mb3738c 172 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 31792344 Common - NAD-dependent deacetylase Mb1182c 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 31794023 Common efpA POSSIBLE INTEGRAL MEMBRANE EFFLUX PROTEIN EFPA Mb2871c 185 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31794634 Common rpsD 30S ribosomal protein S4 Mb3487c 216 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 31794588 Common - hypothetical protein Mb3441 2 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 31793488 Common - HYPOTHETICAL GLYCINE RICH PROTEIN Mb2332c 1 None None None 31793438 Common - Possible transcriptional regulatory protein Mb2282c 86 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31794009 Common ugpB PROBABLE Sn-GLYCEROL-3-PHOSPHATE-BINDING LIPOPROTEIN UGPB Mb2857c 105 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 31791708 Common - POSSIBLE THIOREDOXIN PROTEIN (THIOL-DISULFIDE INTERCHANGE PROTEIN) Mb0539 66 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 31794114 Common drrB PROBABLE DAUNORUBICIN-DIM-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER DRRB Mb2962 26 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 31792094 Common - hypothetical protein Mb0930 91 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 31792906 Common - hypothetical protein Mb1746 61 COG3246 COG3246, Uncharacterized conserved protein Function unknown 31794459 Common birA biotin--protein ligase Mb3307c 174 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 31793719 Common aroD 3-dehydroquinate dehydratase Mb2566c 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 31795072 Pathogen - hypothetical protein Mb3928c 1 None None None 31794290 Common moaC molybdenum cofactor biosynthesis protein C Mb3138 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 31793362 Common - hypothetical protein Mb2206c 42 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 31794924 Common tyrA prephenate dehydrogenase Mb3780 137 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 31793514 Common - hypothetical protein Mb2358 4 None None None 31791301 Pathogen - hypothetical protein Mb0127 1 None None None 31793466 Pathogen - hypothetical protein Mb2310 1 None None None 31793578 Common subI PROBABLE SULFATE-BINDING LIPOPROTEIN SUBI Mb2422c 93 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 31793342 Pathogen PE_PGRS38 conserved hypothetical protein, PE_PGRS Mb2186c 1 None None None 31791181 Common - hypothetical protein Mb0004 20 COG5512 COG5512, Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives General function prediction only 31791188 Common - putative septation inhibitor protein Mb0011c 5 None None None 31792375 Common papA3 PROBABLE CONSERVED POLYKETIDE SYNTHASE ASSOCIATED PROTEIN PAPA3 Mb1214 4 None None None 31792025 Common - hypothetical protein Mb0860c 7 COG4861 COG4861, Uncharacterized protein conserved in bacteria Function unknown 31791999 Common - hypothetical protein Mb0834c 35 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 31792492 Common prfA peptide chain release factor 1 Mb1331 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 31791992 Common - hypothetical protein Mb0827 4 None None None 31794399 Common TB7.3 hypothetical protein Mb3247c 162 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 31794861 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb3715 11 None None None 31792583 Common gmk guanylate kinase Mb1424 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 31794354 Common mesTa PROBABLE EPOXIDE HYDROLASE MESTA [FIRST PART] (EPOXIDE HYDRATASE) (ARENE-OXIDE HYDRATASE) Mb3202c 7 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31791741 Common - POSSIBLE CONSERVED SECRETED PROTEIN Mb0574c 1 None None None 31794002 Pathogen - hypothetical protein Mb2850c 1 COG2253 COG2253, Uncharacterized conserved protein Function unknown 31792563 Common - hypothetical protein Mb1402c 121 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 31792310 Pathogen - CONSERVED HYPOTHETICAL PROTEIN (FRAGMENT) Mb1147c 1 None None None 31794492 Common - hypothetical protein Mb3340c 43 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31792912 Pathogen - hypothetical protein Mb1753c 1 None None None 31794307 Common - hypothetical protein Mb3155 25 COG0778 NfnB, Nitroreductase Energy production and conversion 31794444 Common manC PROBABLE MANNOSE-1-PHOSPHATE GUANYLTRANSFERASE MANC (GDP-MANNOSE PYROPHOSPHORYLASE) (GDP-MANNOSE PHOSPHORYLASE) Mb3292c 234 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 31794288 Common moaA1 PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A MOAA1 Mb3136 200 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 31793082 Common - hypothetical protein Mb1923c 3 COG2353 COG2353, Uncharacterized conserved protein Function unknown 31791891 Common rplV 50S ribosomal protein L22 Mb0726 165 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 31795075 Common - hypothetical protein Mb3932c 1 None None None 31791971 Common - hypothetical protein Mb0806 7 COG3233 COG3233, Predicted deacetylase General function prediction only 31792064 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb0900c 9 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31793264 Pathogen - POSSIBLE TRANSMEMBRANE PROTEIN Mb2107c 1 None None None 31794934 Common - PUTATIVE TWO COMPONENT SENSOR KINASE Mb3790c 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 31793398 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2242 19 None None None 31793497 Common - hypothetical protein Mb2341c 22 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 31791711 Common ccsA POSSIBLE CYTOCHROME C-TYPE BIOGENESIS PROTEIN CCSA Mb0542 131 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 31792610 Common ribH riboflavin synthase subunit beta Mb1451 216 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 31792388 Pathogen PE13 PE FAMILY PROTEIN Mb1227 1 None None None 31794771 Common - hypothetical protein Mb3625 5 None None None 31791449 Common fadE6 PROBABLE ACYL-COA DEHYDROGENASE FADE6 Mb0277c 136 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31793147 Pathogen - hypothetical protein Mb1990 1 COG4679 COG4679, Phage-related protein Function unknown 31792330 Common - POSSIBLE ACETYL-COA ACETYLTRANSFERASE (ACETOACETYL-COA THIOLASE) Mb1167 148 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31793335 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase Mb2179c 207 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 31794529 Common - hypothetical protein Mb3378c 1 None None None 31794177 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb3025 129 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 31792974 Common - PUTATIVE FERREDOXIN Mb1814 9 COG1141 Fer, Ferredoxin Energy production and conversion 31793490 Common - hypothetical protein Mb2334 4 COG2442 COG2442, Uncharacterized conserved protein Function unknown 31793807 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb2654c 10 COG2345 COG2345, Predicted transcriptional regulator Transcription 31791382 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0210c 4 COG0392 COG0392, Predicted integral membrane protein Function unknown 31792551 Common moeY hypothetical protein Mb1390c 172 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 31794410 Common - POSSIBLE LINOLEOYL-COA DESATURASE (DELTA(6)-DESATURASE) Mb3258c 33 COG3239 DesA, Fatty acid desaturase Lipid metabolism 31793247 Common cobG Possible cobalamin biosynthesis protein CobG Mb2090 32 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 31794499 Common sdhA succinate dehydrogenase flavoprotein subunit Mb3347 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 31792305 Common - translation-associated GTPase Mb1142 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 31792266 Common - CONSERVED EXPORTED PROTEIN Mb1104c 15 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 31791443 Common - PROBABLE PERIPLASMIC IRON-TRANSPORT LIPOPROTEIN Mb0271c 49 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 31792056 Common moaD2 PUTATIVE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN D 2 MOAD2 (MOLYBDOPTERIN CONVERTING FACTOR SMALL SUBUNIT) (MOLYBDOPTERIN [MPT] CONVERTING FACTOR, SUBUNIT 1) Mb0892c 8 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 31793411 Common - hypothetical protein Mb2255c 71 COG3323 COG3323, Uncharacterized protein conserved in bacteria Function unknown 31793889 Common - hypothetical protein Mb2736c 13 None None None 31792752 Common - Possible inv protein Mb1593c 51 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 31793482 Pathogen - hypothetical protein Mb2326c 1 None None None 31791959 Common - POSSIBLE 4-CARBOXYMUCONOLACTONE DECARBOXYLASE (CMD) Mb0794 38 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 31793364 Common - hypothetical protein Mb2208c 4 None None None 31792420 Common - PROBABLE TRANSMEMBRANE PROTEIN Mb1259c 19 COG3402 COG3402, Uncharacterized conserved protein Function unknown 31793556 Common mbtF PEPTIDE SYNTHETASE MBTF (PEPTIDE SYNTHASE) Mb2400c 189 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794739 Common fadE32 PROBABLE ACYL-COA DEHYDROGENASE FADE32 Mb3593 39 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31794263 Common lipR PROBABLE ACETYL-HYDROLASE/ESTERASE LIPR Mb3111 76 COG0657 Aes, Esterase/lipase Lipid metabolism 31794643 Common - hypothetical protein Mb3496 7 None None None 31791869 Common tuf elongation factor Tu Mb0704 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 31793763 Common dhaA haloalkane dehalogenase Mb2610 53 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31794748 Common hmp POSSIBLE HEMOGLOBINE-RELATED PROTEIN HMP Mb3602 119 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 31795027 Common menG ribonuclease activity regulator protein RraA Mb3883 104 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 31794941 Pathogen - PROBABLE REMNANT OF A TRANSPOSASE Mb3797c 1 None None None 31794604 Common alr alanine racemase Mb3457c 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 31791270 Common ctpA PROBABLE CATION TRANSPORTER P-TYPE ATPASE A CTPA Mb0095 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 31793489 Pathogen - hypothetical protein Mb2333c 1 None None None 31791819 Common - hypothetical protein Mb0654 20 COG2030 MaoC, Acyl dehydratase Lipid metabolism 31792280 Pathogen PE9 PE FAMILY PROTEIN Mb1117 1 None None None 31793773 Common gabT 4-aminobutyrate aminotransferase Mb2620 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 31793964 Common sirR PROBABLE TRANSCRIPTIONAL REPRESSOR SIRR Mb2811 106 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 31791952 Common cyp51 CYTOCHROME P450 51 CYP51 (CYPL1) (P450-L1A1) (STEROL 14-ALPHA DEMETHYLASE) (LANOSTEROL 14-ALPHA DEMETHYLASE) (P450-14DM) Mb0787c 84 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31794208 Common - hypothetical protein Mb3056 100 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 31792164 Common fadE13 PROBABLE ACYL-COA DEHYDROGENASE FADE13 Mb1000c 153 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31794744 Common - POSSIBLE OXIDOREDUCTASE Mb3598c 127 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 31792364 Common mshB N-Acetyl-1-D-myo-Inosityl-2-Amino-2-Deoxy-alpha- D-Glucopyranoside Deacetylase mshB (GlcNAc-Ins deacetylase) Mb1203 26 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 31792085 Common - PROBABLE OXIDOREDUCTASE Mb0921c 37 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31793461 Common lipM Probable esterase LipM Mb2305 57 COG0657 Aes, Esterase/lipase Lipid metabolism 31791312 Common - PUTATIVE ACETYLTRANSFERASE Mb0138 16 COG3153 COG3153, Predicted acetyltransferase General function prediction only 31792075 Common - hypothetical protein Mb0911c 56 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 31793999 Common - hypothetical protein Mb2847c 29 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 31793686 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) Mb2534 12 COG1309 AcrR, Transcriptional regulator Transcription 31794802 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb3656 3 None None None 31794896 Common cut5 PROBABLE CUTINASE PRECURSOR CUT5 Mb3751 3 None None None 31793182 Common fabG3 POSSIBLE 20-BETA-HYDROXYSTEROID DEHYDROGENASE FABG3 (Cortisone reductase) ((R)-20-hydroxysteroid dehydrogenase) Mb2025 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31793479 Common cut2 PROBABLE CUTINASE CUT2 Mb2323 3 None None None 31792694 Common - PROBABLE METHYLTRANSFERASE Mb1535c 45 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31792443 Common - PROBABLE DRUG-TRANSPORT INTEGRAL MEMBRANE PROTEIN Mb1282 207 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 31791613 Common - PUTATIVE CONSERVED ATPASE Mb0443c 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 31793834 Pathogen - hypothetical protein Mb2681 1 None None None 31794660 Common cpsA POSSIBLE CONSERVED PROTEIN CPSA Mb3514 54 COG1316 LytR, Transcriptional regulator Transcription 31794345 Common - hypothetical protein Mb3193 48 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 31792535 Common - hypothetical protein Mb1374 80 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 31792685 Common - hypothetical protein Mb1526 2 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 31794104 Common - hypothetical protein Mb2952c 33 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 31793732 Common - hypothetical protein Mb2579c 8 COG2402 COG2402, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31793468 Pathogen lppOa Probable conserved lipoprotein lppOa Mb2312 1 None None None 31791884 Pathogen - hypothetical protein Mb0719 1 None None None 31792930 Common - HYPOTHETICAL PROTEIN [SECOND PART] Mb1771 6 None None None 31792972 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb1812 189 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 31791582 Common pks6a PROBABLE MEMBRANE BOUND POLYKETIDE SYNTHASE PKS6A [FIRST PART] Mb0412 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31792884 Common - hypothetical protein Mb1724 8 None None None 31793626 Common ndk nucleoside diphosphate kinase Mb2472c 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 31793970 Common - hypothetical protein Mb2817c 26 COG2977 EntD, Phosphopantetheinyl transferase component of siderophore synthetase Secondary metabolites biosynthesis, transport, and catabolism 31792964 Common - hypothetical protein Mb1804 8 None None None 31791713 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb0544 1 None None None 31793580 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb2424c 1 None None None 31793403 Common - Probable exported protease Mb2247c 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31794572 Common cmaA1 CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 1 CMAA1 (CYCLOPROPANE FATTY ACID SYNTHASE) (CFA SYNTHASE) (CYCLOPROPANE MYCOLIC ACID SYNTHASE 1) Mb3424c 127 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 31793053 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb1894c 5 COG4449 COG4449, Predicted protease of the Abi (CAAX) family General function prediction only 31793560 Common mbtB PHENYLOXAZOLINE SYNTHASE MBTB (PHENYLOXAZOLINE SYNTHETASE) Mb2404c 212 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794234 Common dinP DNA polymerase IV Mb3082 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 31794550 Pathogen PE_PGRS51 PE-PGRS FAMILY PROTEIN Mb3402 1 None None None 31791941 Common PE_PGRS11 PE-PGRS FAMILY PROTEIN Mb0776 6 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 31792700 Common - HYPOTHETICAL PROTEIN [SECOND PART] Mb1541 16 None None None 31791247 Common glyA2 PROBABLE SERINE HYDROXYMETHYLTRANSFERASE GLYA2 (SERINE METHYLASE 2) (SHMT 2) Mb0071c 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 31794390 Common - CONSERVED HYPOTHETICAL ALANINE VALINE RICH PROTEIN Mb3238 5 None None None 31793196 Pathogen - hypothetical protein Mb2039 1 None None None 31793784 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb2631 9 None None None 31792332 Pathogen - hypothetical protein Mb1169c 1 None None None 31793751 Common - hypothetical protein Mb2598c 31 COG4307 COG4307, Uncharacterized protein conserved in bacteria Function unknown 31793829 Common arsC PROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSC Mb2676 160 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 31795002 Common - POSSIBLE RESOLVASE Mb3858c 18 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 31794625 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb3478 5 None None None 31791226 Common - hypothetical protein Mb0050 9 None None None 31792812 Common - Probable two-component system transcriptional regulator Mb1652 224 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 31792512 Common alkAa PUTATIVE ADA REGULATORY PROTEIN ALKAa [FIRST PART] (Regulatory protein of adaptative response) : Methylated-DNA--protein-cysteine methyltransferase (O-6-methylguanine-DNA alkyltransferase) Mb1351c 80 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 31791475 Common - PROBABLE SULFATASE Mb0304c 67 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 31791684 Common - hypothetical protein Mb0514 60 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 31793230 Common - hypothetical protein Mb2073c 182 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 31792743 Common - hypothetical protein Mb1584 11 None None None 31791779 Common - hypothetical protein Mb0613c 45 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 31791450 Common - hypothetical protein Mb0278c 13 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 31794466 Common sigF RNA polymerase sigma factor SigF Mb3314c 214 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 161511527 Common dnaE2 error-prone DNA polymerase Mb3405c 217 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 31792645 Common ctaB protoheme IX farnesyltransferase Mb1486 171 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 31794271 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb3119c 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 31792186 Common rimJ POSSIBLE RIBOSOMAL-PROTEIN-ALANINE ACETYLTRANSFERASE RIMJ (ACETYLATING ENZYME FOR N-TERMINAL OF RIBOSOMAL PROTEIN S5) Mb1022 76 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 31794617 Common - hypothetical protein Mb3470c 1 None None None 31791243 Common icd2 PROBABLE ISOCITRATE DEHYDROGENASE [NADP] ICD2 (OXALOSUCCINATE DECARBOXYLASE) (IDH) (NADP+-SPECIFIC ICDH) (IDP) Mb0067c 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 31793596 Common - hypothetical protein Mb2440c 39 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 31791636 Common - PROBABLE PEPTIDASE Mb0466c 111 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 31791536 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0366 19 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 31794813 Pathogen - hypothetical protein Mb3667 1 None None None 31793201 Common - hypothetical protein Mb2044c 11 COG1396 HipB, Predicted transcriptional regulators Transcription 31793857 Common arsB1 PROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSB1 Mb2704 191 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 31794711 Common - acetaldehyde dehydrogenase Mb3565c 37 COG4569 MhpF, Acetaldehyde dehydrogenase (acetylating) Secondary metabolites biosynthesis, transport, and catabolism 31794433 Common - POSSIBLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE PROTEIN Mb3281c 165 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 31794682 Common fadD17 acyl-CoA synthetase Mb3536 215 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792438 Common - PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE Mb1277c 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 31792990 Common PPE30 PPE FAMILY PROTEIN Mb1830 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793932 Pathogen - hypothetical protein Mb2779c 1 COG5450 COG5450, Transcription regulator of the Arc/MetJ class Transcription 31793084 Common - PROBABLE MEMBRANE PROTEIN Mb1925 1 None None None 31792934 Common pknF ANCHORED-MEMBRANE SERINE/THREONINE-PROTEIN KINASE PKNF (PROTEIN KINASE F) (STPK F) Mb1775 149 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 31795041 Common - hypothetical protein Mb3897 1 None None None 31794314 Common pflA PROBABLE PYRUVATE FORMATE LYASE ACTIVATING PROTEIN PFLA (FORMATE ACETYLTRANSFERASE ACTIVATING ENZYME) ([PYRUVATE FORMATE-LYASE] ACTIVATING ENZYME) Mb3162 85 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 31793694 Pathogen - hypothetical protein Mb2542 1 None None None 31794632 Common rplQ 50S ribosomal protein L17 Mb3485c 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 31793429 Common glpD1 PROBABLE GLYCEROL-3-PHOSPHATE DEHYDROGENASE GLPD1 Mb2273c 149 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 31793238 Common rpsR 30S ribosomal protein S18 Mb2081c 212 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 31791415 Common lpqI PROBABLE CONSERVED LIPOPROTEIN LPQI Mb0243 172 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 31794374 Common uvrD2 PROBABLE DNA HELICASE II HOMOLOG UVRD2 Mb3222c 227 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 31792797 Common trpC indole-3-glycerol-phosphate synthase Mb1637 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 31792393 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN Mb1232 152 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 31794328 Common nuoH NADH dehydrogenase subunit H Mb3176 187 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 31793306 Pathogen PE_PGRS37 conserved hypothetical protein, PE_PGRS Mb2150c 1 COG5281 COG5281, Phage-related minor tail protein Function unknown 31791277 Common fadD10 acyl-CoA synthetase Mb0102 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793655 Common - hypothetical protein Mb2501c 7 None None None 31792716 Common adh Probable alcohol dehydrogenase adh Mb1557 194 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 31793279 Common - hypothetical protein Mb2123c 30 COG2378 COG2378, Predicted transcriptional regulator Transcription 31791340 Common adhE1 PUTATIVE ZINC-TYPE ALCOHOL DEHYDROGENASE (E SUBUNIT) ADHE Mb0167c 125 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 31792034 Common - PROBABLE OXIDASE Mb0869c 121 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 31794866 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb3720 31 COG1714 COG1714, Predicted membrane protein/domain Function unknown 31794387 Common - CONSERVED HYPOTHETICAL THREONIN AND PROLINE RICH PROTEIN Mb3235 1 None None None 31793290 Common prcB proteasome (beta subunit) PrcB Mb2134c 43 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 31792526 Common - nicotinate phosphoribosyltransferase Mb1365c 101 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 31793177 Common ctpF PROBABLE METAL CATION TRANSPORTER P-TYPE ATPASE A CTPF Mb2020 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 31791562 Common - hypothetical protein Mb0392 99 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 31794232 Common - hypothetical protein Mb3080c 113 COG0431 COG0431, Predicted flavoprotein General function prediction only 31792177 Common - PROBABLE ADHESION COMPONENT TRANSPORT TRANSMEMBRANE PROTEIN ABC TRANSPORTER Mb1013 71 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 31793615 Common - PUTATIVE CYCLASE (ADENYLYL-OR GUANYLYL-)(ADENYLATE-OR GUANYLATE-) Mb2461c 98 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31793433 Common - Possible secreted unknown protein Mb2277 2 None None None 31791191 Common pknB TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE B PKNB (PROTEIN KINASE B) (STPK B) Mb0014c 158 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 31792887 Common xerD site-specific tyrosine recombinase XerD Mb1727 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 31791725 Common - hypothetical protein Mb0557c 7 None None None 31793106 Common - hypothetical protein Mb1948 60 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 31792124 Common pstC1 PHOSPHATE-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER PSTC1 Mb0960 220 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 31792675 Common - hypothetical protein Mb1516 92 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 31791262 Common hycD POSSIBLE FORMATE HYDROGENLYASE HYCD (FHL) Mb0087 86 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 31792386 Common fadD36 acyl-CoA synthetase Mb1225 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31795066 Pathogen PE36 PE FAMILY PROTEIN Mb3922c 1 None None None 31792875 Common tyrS tyrosyl-tRNA synthetase Mb1715 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31794367 Common - hypothetical protein Mb3215c 48 COG1615 COG1615, Uncharacterized conserved protein Function unknown 31793950 Common - hypothetical protein Mb2797 10 COG0456 RimI, Acetyltransferases General function prediction only 31795065 Pathogen PPE69 PPE FAMILY PROTEIN Mb3921c 1 None None None 31792997 Common PPE32 PPE FAMILY PROTEIN Mb1837 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791795 Pathogen - hypothetical protein Mb0629 1 None None None 31794215 Common - hypothetical protein Mb3063c 26 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 31794981 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb3837c 6 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 31794704 Pathogen - hypothetical protein Mb3558c 1 None None None 31793344 Common - PROBABLE CONSERVED PROLINE RICH MEMBRANE PROTEIN Mb2188c 3 None None None 31794902 Common - hypothetical protein Mb3757c 66 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 31791210 Common acpA PROBABLE ACYL CARRIER PROTEIN ACPA (ACP) Mb0034 19 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793672 Common - hypothetical protein Mb2520 2 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 31794183 Common lppZ PROBABLE CONSERVED LIPOPROTEIN LPPZ Mb3031 14 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 31792667 Common - PROBABLE MACROLIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER Mb1508 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 31793214 Common hspX HEAT SHOCK PROTEIN HSPX (ALPHA-CRSTALLIN HOMOLOG) (14 kDa ANTIGEN) (HSP16.3) Mb2057c 124 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 31794055 Common mpb53 SOLUBLE SECRETED ANTIGEN MPB53 Mb2903c 58 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 31792778 Common - hypothetical protein Mb1618c 17 None None None 31793731 Common - hypothetical protein Mb2578 6 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31791854 Common end endonuclease IV Mb0689 96 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 31793261 Pathogen - hypothetical protein Mb2104 1 None None None 31791362 Common - hypothetical protein Mb0190 6 None None None 31793526 Pathogen lppQ PROBABLE CONSERVED LIPOPROTEIN LPPQ Mb2370 1 None None None 31794180 Common ilvB1 acetolactate synthase 1 catalytic subunit Mb3028c 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 31791799 Pathogen - hypothetical protein Mb0633c 1 None None None 31791464 Common PE5 PE FAMILY PROTEIN Mb0293 1 None None None 31791905 Common rplF 50S ribosomal protein L6 Mb0740 245 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 31792726 Common - CONSERVED HYPOTHETICAL PROTEIN MEMBER OF yabO/yceC/yfiI FAMILY Mb1567 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 31791549 Common - hypothetical protein Mb0379c 79 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 31792596 Common priA primosome assembly protein PriA Mb1437 187 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 31791922 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb0757 9 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 31795042 Common - hypothetical protein Mb3898 93 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 31794542 Common - POSSIBLE OXIDOREDUCTASE Mb3394 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 31792826 Common - hypothetical protein Mb1666c 15 COG0627 COG0627, Predicted esterase General function prediction only 31793417 Common - hypothetical protein Mb2261 12 COG3662 COG3662, Uncharacterized protein conserved in bacteria Function unknown 31792834 Common - hypothetical protein Mb1674 48 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31791550 Common - PROBABLE CARBON MONOXYDE DEHYDROGENASE (LARGE CHAIN) Mb0380c 116 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 31791355 Common - PROBABLE CONSERVED MCE ASSOCIATED PROTEIN Mb0183 1 None None None 31793375 Common qcrB Probable Ubiquinol-cytochrome C reductase QcrB (cytochrome B subunit) Mb2219 142 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 31791385 Common - hypothetical protein Mb0213c 6 None None None 31791930 Pathogen - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0765c 1 None None None 161511533 Common dinX DNA polymerase IV Mb1564 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 31792324 Common - hypothetical protein Mb1161 65 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 31792862 Common - hypothetical protein Mb1703 7 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 31793642 Common clpP ATP-dependent Clp protease proteolytic subunit Mb2488c 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 31795084 Common sigMa RNA polymerase sigma factor SigM Mb3941 146 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 31791601 Common thiC thiamine biosynthesis protein ThiC Mb0431c 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 31791236 Common - hypothetical protein Mb0060 12 None None None 31794010 Common ugpE PROBABLE Sn-GLYCEROL-3-PHOSPHATE TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER UGPE Mb2858c 159 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 31793865 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE AND LEUCINE RICH PROTEIN Mb2712c 16 None None None 31792203 Pathogen - hypothetical protein Mb1040 1 None None None 31791429 Common hsp HEAT SHOCK PROTEIN HSP (HEAT-STRESS-INDUCED RIBOSOME-BINDING PROTEIN A) Mb0257c 83 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 31795015 Common bfrB POSSIBLE BACTERIOFERRITIN BFRB Mb3871 75 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 31794144 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb2992c 17 COG4243 COG4243, Predicted membrane protein Function unknown 31793025 Common - hypothetical protein Mb1866c 66 COG2936 COG2936, Predicted acyl esterases General function prediction only 31793157 Common - hypothetical protein Mb2000 3 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31794957 Common rfbB POSSIBLE DTDP-GLUCOSE 4,6-DEHYDRATASE RFBB Mb3813 234 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 31791283 Common rpmB 50S ribosomal protein L28 Mb0108c 124 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 31791916 Common - hypothetical protein Mb0751 2 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 31794753 Common lppH POSSIBLE CONSERVED LIPOPROTEIN LPPH Mb3607 1 None None None 31791831 Common - hypothetical protein Mb0666c 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 31794536 Pathogen - hypothetical protein Mb3388c 1 None None None 31794878 Pathogen - CONSERVED HYPOTHETICAL PROLINE RICH PROTEIN Mb3733c 1 None None None 31791319 Pathogen - hypothetical protein Mb0146c 1 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 31792781 Common nadB L-aspartate oxidase Mb1621 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 31792205 Common pth peptidyl-tRNA hydrolase Mb1042c 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 31792661 Common fadE15 PROBABLE ACYL-COA DEHYDROGENASE FADE15 Mb1502c 147 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31791821 Common - hypothetical protein Mb0656 23 COG2030 MaoC, Acyl dehydratase Lipid metabolism 31794991 Common - PUTATIVE PHOSPHOTRANSFERASE Mb3847 19 COG3231 Aph, Aminoglycoside phosphotransferase Translation, ribosomal structure and biogenesis 31794785 Common folE GTP cyclohydrolase I Mb3639c 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 31791540 Common fba fructose-bisphosphate aldolase Mb0370c 115 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 31792461 Common - CONSERVED PROBABLE SECRETED PROTEIN Mb1300c 4 None None None 31793298 Common - POSSIBLE RNA METHYLTRANSFERASE Mb2142c 50 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 31794610 Common - hypothetical protein Mb3463c 208 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 31791187 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb0010c 3 None None None 31793113 Common lppF PROBABLE CONSERVED LIPOPROTEIN LPPF Mb1956c 2 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 31791737 Common menD 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase Mb0570 77 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 31793709 Common mrr PROBABLE RESTRICTION SYSTEM PROTEIN MRR Mb2557c 54 COG1715 Mrr, Restriction endonuclease Defense mechanisms 31794964 Common - short chain dehydrogenase Mb3820 188 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 31792566 Common - hypothetical protein Mb1406 117 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 31792286 Common glyA serine hydroxymethyltransferase Mb1123 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 31792586 Common metK S-adenosylmethionine synthetase Mb1427 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 31794061 Common - PUTATIVE TRANSPOSASE Mb2909c 54 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 31794265 Common adhD PROBABLE ZINC-TYPE ALCOHOL DEHYDROGENASE ADHD (ALDEHYDE REDUCTASE) Mb3113 207 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 31794471 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ASNC-FAMILY) Mb3319c 153 COG1522 Lrp, Transcriptional regulators Transcription 31791559 Common pyrE orotate phosphoribosyltransferase Mb0389c 107 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 31793700 Pathogen PE26 PE FAMILY PROTEIN Mb2548 1 None None None 31792612 Pathogen lprH PROBABLE LIPOPROTEIN LPRH Mb1453 1 None None None 31791614 Common pssA PROBABLE CDP-DIACYLGLYCEROL--SERINE O-PHOSPHATIDYLTRANSFERASE PSSA (PS SYNTHASE) (PHOSPHATIDYLSERINE SYNTHASE) Mb0444c 135 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 31792986 Common - hypothetical protein Mb1826 78 COG1223 COG1223, Predicted ATPase (AAA+ superfamily) General function prediction only 31794661 Common - short chain dehydrogenase Mb3515c 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31792062 Common - hypothetical protein Mb0898c 29 COG4398 COG4398, Uncharacterized protein conserved in bacteria Function unknown 31792560 Common - hypothetical protein Mb1399c 38 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 31794292 Common - POSSIBLE PHOSPHATASE Mb3140 9 COG0546 Gph, Predicted phosphatases General function prediction only 31795056 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb3912c 3 None None None 31793741 Common - hypothetical protein Mb2588 3 None None None 31794755 Common arsB2 POSSIBLE ARSENICAL PUMP INTEGRAL MEMBRANE PROTEIN ARSB2 Mb3609 4 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 31794226 Common nrdF ribonucleotide-diphosphate reductase subunit beta Mb3074c 149 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 31793249 Common cobI Probable bifunctional protein, CobI-CobJ fusion protein: S-adenosyl-L-methionine-precorrin-2 methyl transferase + precorrin-3 methylase Mb2092 148 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 31794987 Common - hypothetical protein Mb3843c 133 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 31791990 Common - hypothetical protein Mb0825c 11 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 31791771 Common mce2A MCE-FAMILY PROTEIN MCE2A Mb0604 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31791756 Common - hypothetical protein Mb0589c 60 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 31792204 Common pks16 acyl-CoA synthetase Mb1041 215 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31794416 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN Mb3264c 111 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 31792774 Pathogen - Partial REP13E12 repeat protein Mb1614c 1 None None None 31792557 Common PPE19 PPE FAMILY PROTEIN Mb1396c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794411 Common - HYPOTHETICAL OXIDOREDUCTASE Mb3259c 119 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 31793646 Common - ribose-5-phosphate isomerase B Mb2492c 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 31793790 Common tesB2 PROBABLE ACYL-COA THIOESTERASE II TESB2 (TEII) Mb2637c 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 31792914 Common - PROBABLE OXIDOREDUCTASE Mb1755 41 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 31791777 Common - hypothetical protein Mb0611c 10 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31793606 Common - hypothetical protein Mb2450c 119 COG0714 COG0714, MoxR-like ATPases General function prediction only 31792099 Common - hypothetical protein Mb0935 49 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 31794780 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN RICH IN ALANINE AND ARGININE AND PROLINE Mb3634c 3 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 31794894 Common - hypothetical protein Mb3749c 24 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 31793809 Common TB31.7 hypothetical protein Mb2656 43 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 31793396 Common lipB lipoyltransferase Mb2240 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 31795059 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb3915c 2 None None None 31792683 Common - POSSIBLE EXPORTED CONSERVED PROTEIN Mb1524 219 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 31794845 Common - POSSIBLE MEMBRANE PROTEIN Mb3699 1 None None None 31792948 Pathogen wag22b PE-PGRS FAMILY PROTEIN WAG22B [SECOND PART] Mb1789c 1 None None None 31794175 Common - hypothetical protein Mb3023c 75 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 31792007 Common - hypothetical protein Mb0842 17 COG0456 RimI, Acetyltransferases General function prediction only 31791297 Common fadD7 acyl-CoA synthetase Mb0123 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792303 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase Mb1140 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 31792239 Pathogen - hypothetical protein Mb1077c 1 None None None 31794494 Common add adenosine deaminase Mb3342c 99 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 31791973 Common - CONSERVED HYPOTHETICAL PROTEIN [SECOND PART] Mb0808 27 COG3573 COG3573, Predicted oxidoreductase General function prediction only 31793139 Common - hypothetical protein Mb1982 3 None None None 31792365 Common - hypothetical protein Mb1204 5 None None None 31794004 Common - hypothetical protein Mb2852c 9 COG4293 COG4293, Uncharacterized protein conserved in bacteria Function unknown 31794418 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb3266c 19 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 31794118 Common fadD28 acyl-CoA synthetase Mb2966 203 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792336 Common echA11 enoyl-CoA hydratase Mb1173c 136 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31793158 Common - POSSIBLE CONSERVED PERMEASE Mb2001c 185 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 31795023 Common - hypothetical protein Mb3879 7 None None None 31794551 Common - POSSIBLE OXIDOREDUCTASE Mb3403c 26 COG0778 NfnB, Nitroreductase Energy production and conversion 31791519 Common iniB ISONIAZID INDUCTIBLE GENE PROTEIN INIB Mb0348 1 None None None 31794770 Common lpqF PROBABLE CONSERVED LIPOPROTEIN LPQF Mb3624 12 COG2367 PenP, Beta-lactamase class A Defense mechanisms 31791235 Common dnaB replicative DNA helicase Mb0059 221 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 31792020 Pathogen PE_PGRS12 PE-PGRS FAMILY PROTEIN Mb0855 1 None None None 31794523 Common icd1 isocitrate dehydrogenase Mb3371c 64 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 31794259 Common pknK PROBABLE SERINE/THREONINE-PROTEIN KINASE TRANSCRIPTIONAL REGULATORY PROTEIN PKNK (PROTEIN KINASE K) (STPK K) Mb3107c 160 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 31793926 Common - hypothetical protein Mb2773c 162 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 31791336 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY TETR-FAMILY) Mb0163 85 COG1309 AcrR, Transcriptional regulator Transcription 31793406 Common - hypothetical protein Mb2250 13 COG5607 COG5607, Uncharacterized conserved protein Function unknown 31793108 Common aceA isocitrate lyase Mb1950 126 COG2224 AceA, Isocitrate lyase Energy production and conversion 31793667 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (LUXR-FAMILY) Mb2515c 36 COG3903 COG3903, Predicted ATPase General function prediction only 31791717 Common pnp 5'-methylthioadenosine phosphorylase Mb0549 125 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 31793769 Common - POSSIBLE CONSERVED LIPOPROTEIN Mb2616c 13 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 31792595 Common - POSSIBLE MEMBRANE PROTEIN Mb1436 20 COG3714 COG3714, Predicted membrane protein Function unknown 31793263 Common lppJ Possible lipoprotein LppJ Mb2106 1 None None None 31794252 Common - hypothetical protein Mb3100c 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 31791391 Common - POSSIBLE METHYLTRANSFERASE (METHYLASE) Mb0219c 91 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 31791857 Common echA4 enoyl-CoA hydratase Mb0692 165 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31792936 Common - hypothetical protein Mb1777 3 None None None 31792530 Common - hypothetical protein Mb1369 31 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 31793132 Common ribA1 Probable Riboflavin biosynthesis protein ribA1 (GTP cyclohydrolase II) Mb1975 209 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 31791207 Pathogen - hypothetical protein Mb0031 1 None None None 31794838 Common - PUTATIVE PROTEASE Mb3692c 5 None None None 31792475 Common oppB PROBABLE OLIGOPEPTIDE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER OPPB Mb1314c 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 31793575 Common cysA1 PROBABLE SULFATE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER CYSA1 Mb2419c 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 31791451 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0279c 8 COG1309 AcrR, Transcriptional regulator Transcription 31792308 Common - POSSIBLE EXPORTED PROTEIN Mb1145 2 None None None 31793057 Common - acetyl-CoA acetyltransferase Mb1898 13 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31794633 Common rpoA DNA-directed RNA polymerase subunit alpha Mb3486c 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 31794075 Common fdhD formate dehydrogenase accessory protein Mb2923c 134 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 31793568 Common nirA PROBABLE FERREDOXIN-DEPENDANT NITRITE REDUCTASE NIRA Mb2412 154 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 31792892 Common PPE23 PPE FAMILY PROTEIN Mb1732c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793457 Common - Probable dehydrogenase Mb2301 198 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 31794608 Common - POSSIBLE TRANSPOSASE Mb3461c 82 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 31793801 Pathogen PE_PGRS45 PE-PGRS FAMILY PROTEIN Mb2648c 1 COG4907 COG4907, Predicted membrane protein Function unknown 31792079 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0915c 18 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31795033 Common gltB PUTATIVE FERREDOXIN-DEPENDENT GLUTAMATE SYNTHASE [NADPH] (LARGE SUBUNIT) GLTB (L-GLUTAMATE SYNTHASE) (L-GLUTAMATE SYNTHETASE) (NADH-GLUTAMATE SYNTHASE) (GLUTAMATE SYNTHASE (NADH))(NADPH-GOGAT) Mb3889c 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 31792037 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN Mb0872 37 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 31793285 Common - hypothetical protein Mb2129c 5 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794589 Common - hypothetical protein Mb3442 2 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794190 Common - hypothetical protein Mb3038 9 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 31794046 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2894c 207 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 31792373 Common - hypothetical protein Mb1212c 11 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 31794456 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit Mb3304c 185 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 31794954 Common rfbE PROBABLE O-ANTIGEN/LIPOPOLYSACCHARIDE TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER RFBE Mb3810 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 31792027 Common - hypothetical protein Mb0862 116 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31792070 Common - PROBABLE TRANSMEMBRANE PROTEIN Mb0906 2 None None None 31793875 Common sigA RNA polymerase sigma factor RpoD Mb2722 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 31794655 Common - CONSERVED HYPOTHETICAL PROTEIN [SECOND PART] Mb3509c 27 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 31792000 Common - 4-amino-4-deoxychorismate lyase Mb0835 124 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 31792230 Pathogen esxJ PUTATIVE ESAT-6 LIKE PROTEIN 2 Mb1067c 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31794112 Common ppsE PHENOLPTHIOCEROL SYNTHESIS TYPE-I POLYKETIDE SYNTHASE PPSE Mb2960 209 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794709 Common PPE62 PPE FAMILY PROTEIN Mb3563c 10 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31795005 Pathogen - hypothetical protein Mb3861 1 None None None 31792385 Common - hypothetical protein Mb1224 15 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31792973 Common cyp143 PROBABLE CYTOCHROME P450 143 CYP143 Mb1813c 73 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31791896 Common atsAa POSSIBLE ARYLSULFATASE ATSAa [FIRST PART] (ARYL-SULFATE SULPHOHYDROLASE) (ARYLSULPHATASE) Mb0731 65 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 31794488 Common pmmB PROBABLE PHOSPHOMANNOMUTASE PMMB (PHOSPHOMANNOSE MUTASE) Mb3336 235 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 31791947 Common - hypothetical protein Mb0782c 46 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 31793039 Common ureB urease subunit beta Mb1880 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 31792489 Common thrB homoserine kinase Mb1328 75 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 31792084 Common gltA type II citrate synthase Mb0920 194 COG0372 GltA, Citrate synthase Energy production and conversion 31795082 Common - hypothetical protein Mb3939 10 None None None 31792580 Common PE15 PE FAMILY PROTEIN Mb1421 1 None None None 31793391 Common - hypothetical protein Mb2235 23 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31792843 Common argF ornithine carbamoyltransferase Mb1684 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 31791591 Common mutT3 POSSIBLE MUTATOR PROTEIN MUTT3 (7,8-DIHYDRO-8-OXOGUANINE-TRIPHOSPHATASE) (8-OXO-DGTPASE) (DGTP PYROPHOSPHOHYDROLASE) Mb0421 21 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 31791963 Common - hypothetical protein Mb0798 5 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 31792458 Common pknH PROBABLE TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE H PKNH (PROTEIN KINASE H) (STPK H) Mb1297c 154 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 31792941 Common PPE24 PPE FAMILY PROTEIN Mb1782c 3 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791444 Common oplA PROBABLE 5-OXOPROLINASE OPLA (5-OXO-L-PROLINASE) (PYROGLUTAMASE) (5-OPASE) Mb0272c 117 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31791575 Common lpqK POSSIBLE CONSERVED LIPOPROTEIN LPQK Mb0405c 67 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 31793426 Common kasB 3-oxoacyl-(acyl carrier protein) synthase II Mb2270 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793545 Common phoH1 PROBABLE PHOH-LIKE PROTEIN PHOH1 (PHOSPHATE STARVATION-INDUCIBLE PROTEIN PSIH) Mb2389c 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 31791290 Common gca POSSIBLE GDP-MANNOSE 4,6-DEHYDRATASE GCA (GDP-D-MANNOSE DEHYDRATASE) Mb0116 230 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 31793016 Common gcvH glycine cleavage system protein H Mb1857 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 31795078 Pathogen esxF PUTATIVE ESAT-6 LIKE PROTEIN 13 (HYPOTHETICAL ALANINE AND GLYCINE RICH PROTEIN) Mb3935c 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31792909 Pathogen - hypothetical protein Mb1750c 1 None None None 31791852 Common rpoC DNA-directed RNA polymerase subunit beta' Mb0687 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 31793759 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb2606c 1 None None None 31793446 Common - hypothetical protein Mb2290c 25 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 31794035 Common aldC PROBABLE ALDEHYDE DEHYDROGENASE ALDC Mb2883c 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 31792220 Pathogen kdpF Probable membrane protein kdpF Mb1057 1 None None None 31791384 Common mmpL3 POSSIBLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL3 Mb0212c 51 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31792496 Common - hypothetical protein Mb1335 1 None None None 31794338 Common - POSSIBLE DIOXYGENASE Mb3186c 92 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 31791706 Common hemL glutamate-1-semialdehyde aminotransferase Mb0537 234 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 31792695 Common - hypothetical protein Mb1536c 38 COG3360 COG3360, Uncharacterized conserved protein Function unknown 31791873 Common - hypothetical protein Mb0708c 1 None None None 31793528 Common dnaG DNA primase Mb2372c 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 31792524 Common glgP PROBABLE GLYCOGEN PHOSPHORYLASE GLGP Mb1363 150 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 31791822 Common secE preprotein translocase subunit SecE Mb0657 6 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 31794824 Pathogen - hypothetical protein Mb3678c 1 None None None 31792423 Common - POSSIBLE MEMBRANE PROTEIN Mb1262c 18 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 31792640 Common opcA PUTATIVE OXPP CYCLE PROTEIN OPCA Mb1481c 23 COG3429 COG3429, Glucose-6-P dehydrogenase subunit Carbohydrate transport and metabolism 31794145 Common - POSSIBLE CONSERVED MEMBRANE OR SECRETED PROTEIN Mb2993c 13 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 31793001 Common - PROBABLE DEHYDROGENASE Mb1842c 88 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 31791792 Pathogen - hypothetical protein Mb0626 1 None None None 31792464 Common - PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER Mb1303c 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 31792168 Pathogen - hypothetical protein Mb1004c 1 None None None 31793919 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb2766c 26 COG1396 HipB, Predicted transcriptional regulators Transcription 31792957 Pathogen PE_PGRS31 PE-PGRS FAMILY PROTEIN Mb1797 1 None None None 31791198 Common - hypothetical protein Mb0021c 110 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 31793986 Common - hypothetical protein Mb2834 2 None None None 31792519 Common fadA4 acetyl-CoA acetyltransferase Mb1358 175 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31793961 Common rpsO 30S ribosomal protein S15 Mb2808c 214 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 31792311 Common - hypothetical protein Mb1148 15 COG1359 COG1359, Uncharacterized conserved protein Function unknown 31793701 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb2549c 4 None None None 31792259 Pathogen PE_PGRS20 PE-PGRS FAMILY PROTEIN Mb1097c 1 None None None 31791997 Common purM phosphoribosylaminoimidazole synthetase Mb0832 230 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 31793441 Common - hypothetical protein Mb2285c 145 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 31793913 Common - hypothetical protein Mb2760 5 COG4308 LimA, Limonene-1,2-epoxide hydrolase Secondary metabolites biosynthesis, transport, and catabolism 31794720 Common fadE28 PROBABLE ACYL-COA DEHYDROGENASE FADE28 Mb3574c 116 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31791935 Common - hypothetical protein Mb0770 4 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794797 Common - hypothetical protein Mb3651c 87 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 31792046 Common - aminotransferase Mb0881c 235 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 31793941 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Mb2788c 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31795077 Pathogen esxE PUTATIVE ESAT-6 LIKE PROTEIN 12 (HYPOTHETICAL ALANINE RICH PROTEIN) Mb3934c 2 None None None 31793168 Common - hypothetical protein Mb2011c 1 COG5654 COG5654, Uncharacterized conserved protein Function unknown 31792624 Common PE16 PE FAMILY PROTEIN Mb1465 1 None None None 31792707 Common fadD25 acyl-CoA synthetase Mb1548 200 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793126 Common fadE17 PROBABLE ACYL-COA DEHYDROGENASE FADE17 Mb1969c 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31794567 Common - POSSIBLE TRANSPOSASE Mb3419 22 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 31793814 Common - hypothetical protein Mb2661 1 None None None 31794154 Common - PROBABLE RESOLVASE Mb3002c 62 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 31792852 Common pks11 Possible chalcone synthase pks11 Mb1693 44 COG3424 BcsA, Predicted naringenin-chalcone synthase Secondary metabolites biosynthesis, transport, and catabolism 31794200 Common PE29 PE FAMILY PROTEIN Mb3048c 1 None None None 31794300 Common PPE49 PPE FAMILY PROTEIN Mb3148c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792145 Common purN phosphoribosylglycinamide formyltransferase Mb0981 218 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 31793842 Common - hypothetical protein Mb2689c 85 COG1485 COG1485, Predicted ATPase General function prediction only 31792282 Pathogen celA2a PROBABLE CELLULASE CELA2A (ENDO-1,4-BETA-GLUCANASE) (ENDOGLUCANASE) (CARBOXYMETHYL CELLULASE) Mb1119 1 None None None 31793713 Common - PROBABLE AMINO ACID DECARBOXYLASE Mb2560c 81 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 31793685 Common fadD35 acyl-CoA synthetase Mb2533c 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793043 Common ureD Probable urease accessory protein ureD Mb1884 6 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 31792474 Common oppC PROBABLE OLIGOPEPTIDE-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER OPPC Mb1313c 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 31792659 Common - POSSIBLE NITROGEN FIXATION RELATED PROTEIN Mb1500 121 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 31794224 Common - hypothetical protein Mb3072c 7 None None None 31793948 Common dapB dihydrodipicolinate reductase Mb2795c 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 31791867 Common rpsG 30S ribosomal protein S7 Mb0702 243 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 31792782 Common nadC nicotinate-nucleotide pyrophosphorylase Mb1622 203 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 31791667 Common - hypothetical protein Mb0497 10 None None None 31792650 Common - PROBABLE UNIDENTIFIED ANTIBIOTIC-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER Mb1491c 18 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 31793170 Common - POSSIBLE DEHYDROGENASE (FRAGMENT) Mb2013c 3 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31794171 Common leuB 3-isopropylmalate dehydrogenase Mb3019c 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 31793315 Common - hypothetical protein Mb2159c 55 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 31794854 Common - hypothetical protein Mb3708 75 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 31793828 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ARSR-FAMILY) Mb2675 170 COG0640 ArsR, Predicted transcriptional regulators Transcription 31793905 Common - CONSERVED HYPOTHETICAL ALANINE, ARGININE-RICH PROTEIN Mb2752c 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 31793761 Common - CONSERVED HYPOTHETICAL PROTEIN [SECOND PART] Mb2608 22 COG1409 Icc, Predicted phosphohydrolases General function prediction only 31793476 Common - hypothetical protein Mb2320 188 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 31793495 Common - hypothetical protein Mb2339 1 None None None 31794479 Common atsB PROBABLE ARYLSULFATASE ATSB (ARYL-SULFATE SULPHOHYDROLASE) (SULFATASE) Mb3327c 78 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 31793661 Common plsB2 glycerol-3-phosphate acyltransferase Mb2507c 46 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 31793539 Common recO DNA repair protein RecO Mb2383c 62 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 31791526 Pathogen - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0356 2 None None None 31792197 Common - hypothetical protein Mb1033 5 None None None 31791701 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb0532c 4 COG2382 Fes, Enterochelin esterase and related enzymes Inorganic ion transport and metabolism 31793328 Common - hypothetical protein Mb2172c 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 31794195 Common PPE46 PPE FAMILY PROTEIN Mb3043c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791827 Common mmaA3 METHOXY MYCOLIC ACID SYNTHASE 3 MMAA3 (METHYL MYCOLIC ACID SYNTHASE 3) (MMA3) (HYDROXY MYCOLIC ACID SYNTHASE) Mb0662c 127 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 31793555 Common mbtG LYSINE-N-OXYGENASE MBTG (L-LYSINE 6-MONOOXYGENASE) (LYSINE N6-HYDROXYLASE) Mb2399c 6 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 31794509 Pathogen - HYPOTHETICAL PROTEIN [SECOND PART] Mb3357 1 None None None 31791398 Common lipC PROBABLE ESTERASE LIPC Mb0226 120 COG0657 Aes, Esterase/lipase Lipid metabolism 31791512 Common rmlA PROBABLE GLUCOSE-1-PHOSPHATE THYMIDYLYLTRANSFERASE RMLA (DTDP-GLUCOSE SYNTHASE) (DTDP-GLUCOSE PYROPHOSPHORYLASE) Mb0341 231 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 31794761 Common lpqE POSSIBLE CONSERVED LIPOPROTEIN LPQE Mb3615 4 None None None 31791830 Common lipG PROBABLE LIPASE/ESTERASE LIPG Mb0665c 42 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31793076 Common - chorismate mutase Mb1917c 11 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 31791674 Common - hypothetical protein Mb0504c 3 None None None 31794388 Common - hypothetical protein Mb3236c 12 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 31794340 Common - POSSIBLE CONSERVED SECRETED PROTEIN Mb3188c 56 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 31792215 Common - hypothetical protein Mb1052 18 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 31791783 Common - PROBABLE TWO COMPONENT SENSOR KINASE (FIRST PART) Mb0617c 13 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 31791672 Common - PROBABLE OXIDOREDUCTASE GMC-TYPE Mb0502c 53 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 31793205 Pathogen - hypothetical protein Mb2048c 1 None None None 31792715 Common fadD24 acyl-CoA synthetase Mb1556 199 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793614 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb2460c 167 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 31795097 Common rpmH 50S ribosomal protein L34 Mb3955c 189 None None None 31792229 Pathogen esxI PUTATIVE ESAT-6 LIKE PROTEIN 1 Mb1066c 1 None None None 31794599 Common groES co-chaperonin GroES Mb3452c 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 31793656 Common - hypothetical protein Mb2502c 20 COG0824 FcbC, Predicted thioesterase General function prediction only 31794368 Common - POSSIBLE CONSERVED SECRETED PROTEIN Mb3216c 53 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 31791308 Common fbpC SECRETED ANTIGEN 85-C FBPC (85C) (ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C) Mb0134c 6 COG0627 COG0627, Predicted esterase General function prediction only 31793637 Common - PUTATIVE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN Mb2483c 17 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 31793774 Common fadD9 PROBABLE FATTY-ACID-CoA LIGASE FADD9 (FATTY-ACID-COA SYNTHETASE) (FATTY-ACID-COA SYNTHASE) Mb2621 195 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 31793251 Common blaC CLASS A BETA-LACTAMASE BLAC Mb2094c 51 COG2367 PenP, Beta-lactamase class A Defense mechanisms 31793811 Common - PROBABLE CONSERVED TRANSMEMBRANE ALANINE AND LEUCINE RICH PROTEIN Mb2658c 45 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 31792092 Common accD3 PUTATIVE ACETYL-COENZYME A CARBOXYLASE CARBOXYL TRANSFERASE (SUBUNIT BETA) ACCD3 (ACCASE BETA CHAIN) Mb0928c 208 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 31791988 Common pepC putative aminopeptidase 2 Mb0823 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 31794027 Common - POSSIBLE MAGNESIUM CHELATASE Mb2875c 70 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 31793517 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN Mb2361c 189 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31794885 Common cobQ2 POSSIBLE COBYRIC ACID SYNTHASE COBQ2 Mb3740 69 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 31794863 Common moxR2 PUTATIVE METHANOL DEHYDROGENASE TRANSCRIPTIONAL REGULATORY PROTEIN MOXR2 Mb3717 175 COG0714 COG0714, MoxR-like ATPases General function prediction only 31793797 Common pgsA1 PROBABLE PI SYNTHASE PGSA1 (PHOSPHATIDYLINOSITOL SYNTHASE) (CDP-DIACYLGLYCEROL--INOSITOL3-PHOSPHATIDYLTRANSFERASE) Mb2644c 66 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 31791744 Common grcC1 PROBABLE POLYPRENYL-DIPHOSPHATE SYNTHASE GRCC1 (POLYPRENYL PYROPHOSPHATE SYNTHETASE) Mb0577 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 31791981 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY GNTR-FAMILY) Mb0816c 128 COG2188 PhnF, Transcriptional regulators Transcription 31794856 Common cyp137 PROBABLE CYTOCHROME P450 137 CYP137 Mb3710c 93 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31791471 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0300 1 None None None 31792318 Common ephC PROBABLE EPOXIDE HYDROLASE EPHC (EPOXIDE HYDRATASE) Mb1155 98 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31794470 Common lat L-lysine aminotransferase Mb3318c 236 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 31792232 Pathogen PE8 PE FAMILY PROTEIN Mb1069c 1 None None None 31794818 Common cspA PROBABLE COLD SHOCK PROTEIN A CSPA Mb3672c 181 COG1278 CspC, Cold shock proteins Transcription 31792573 Common pyrR pyrimidine regulatory protein PyrR Mb1414 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 31791318 Common - hypothetical protein Mb0145 44 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 31792383 Common - hypothetical protein Mb1222 80 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31791473 Common tam PROBABLE TRANS-ACONITATE METHYLTRANSFERASE TAM Mb0302 71 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 31791260 Common - PROBABLE OXIDOREDUCTASE Mb0085 186 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 31793725 Pathogen lppA PROBABLE CONSERVED LIPOPROTEIN LPPA Mb2572 1 None None None 31791911 Common - hypothetical protein Mb0746c 25 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31794053 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb2901 4 None None None 31793496 Common - hypothetical protein Mb2340c 3 COG2128 COG2128, Uncharacterized conserved protein Function unknown 31793886 Common - CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN Mb2733 20 None None None 31792143 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0979 1 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31792400 Common folP2 PROBABLE DIHYDROPTEROATE SYNTHASE 2 FOLP2 (DHPS 2) (Dihydropteroate pyrophosphorylase 2) Mb1239 197 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 31791182 Common gyrB DNA gyrase subunit B Mb0005 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 31791607 Common def peptide deformylase Mb0437c 204 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 31793296 Common lppK Probable conserved lipoprotein lppK Mb2140 2 None None None 31792321 Common ppdK pyruvate phosphate dikinase Mb1158c 118 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 31794422 Common - hypothetical protein Mb3270c 26 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 31792669 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1510c 81 COG1309 AcrR, Transcriptional regulator Transcription 31794356 Common - hypothetical protein Mb3204 11 None None None 31794029 Common mqo malate:quinone oxidoreductase Mb2877c 55 COG0579 COG0579, Predicted dehydrogenase General function prediction only 31794725 Common - short chain dehydrogenase Mb3579c 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31794730 Common fdxB POSSIBLE ELECTRON TRANSFER PROTEIN FDXB Mb3584 146 COG3239 DesA, Fatty acid desaturase Lipid metabolism 31792326 Common - hypothetical protein Mb1163 5 None None None 31793373 Common qcrC Probable Ubiquinol-cytochrome C reductase QcrC (cytochrome C subunit) Mb2217 18 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 31794684 Pathogen PE_PGRS54 PE-PGRS FAMILY PROTEIN Mb3538 1 None None None 31792161 Common fadE12 PROBABLE ACYL-COA DEHYDROGENASE FADE12 Mb0997c 158 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31794977 Common fbpD SECRETED MPT51/MPB51 ANTIGEN PROTEIN FBPD (MPT51/MPB51 ANTIGEN 85 COMPLEX C) (AG58C) (MYCOLYL TRANSFERASE 85C) (FIBRONECTIN-BINDING PROTEIN C) (85C) Mb3833c 6 COG0627 COG0627, Predicted esterase General function prediction only 31792598 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1439 53 COG1846 MarR, Transcriptional regulators Transcription 31792501 Common atpA F0F1 ATP synthase subunit alpha Mb1340 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 31793943 Common PPE43 PPE FAMILY PROTEIN Mb2790c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794059 Common pyrH uridylate kinase Mb2907c 231 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 31792514 Common - POSSIBLE ADENYLATE CYCLASE (ATP PYROPHOSPHATE-LYASE) (ADENYLYL CYCLASE) Mb1353c 52 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31793014 Common - hypothetical protein Mb1855 25 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 31793115 Common lipD PROBABLE LIPASE LIPD Mb1958 66 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 31792419 Common - PROBABLE TRANSMEMBRANE PROTEIN Mb1258c 6 COG3428 COG3428, Predicted membrane protein Function unknown 31794792 Pathogen - CONSERVED HYPOTHETICAL ALANINE AND GLYCINE RICH PROTEIN Mb3646c 1 None None None 31793674 Common - hypothetical protein Mb2522 7 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794578 Common phyA PROBABLE PHYTOENE SYNTHASE PHYA Mb3430c 100 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 31791326 Common - PROBABLE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE Mb0153 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31793616 Common rbsK RIBOKINASE RBSK Mb2462 116 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 31794907 Common - hypothetical protein Mb3762 33 COG1839 COG1839, Uncharacterized conserved protein Function unknown 31791430 Common nirB PROBABLE NITRITE REDUCTASE [NAD(P)H] LARGE SUBUNIT [FAD FLAVOPROTEIN] NIRB Mb0258 205 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 31791651 Pathogen - hypothetical protein Mb0481c 1 None None None 31792006 Common - TRANSCRIPTIONAL REGULATORY PROTEIN Mb0841 194 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31792837 Common pheT phenylalanyl-tRNA synthetase subunit beta Mb1677 214 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 31793620 Common proB gamma-glutamyl kinase Mb2466c 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 31794750 Common fadE34 PROBABLE ACYL-COA DEHYDROGENASE FADE34 Mb3604c 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31792775 Common bioB biotin synthase Mb1615 182 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 31794671 Common lprN POSSIBLE MCE-FAMILY LIPOPROTEIN LPRN (MCE-FAMILY LIPOPROTEIN MCE4E) Mb3525c 7 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31791281 Common ctpB PROBABLE CATION-TRANSPORTER P-TYPE ATPASE B CTPB Mb0106c 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 31794502 Common - hypothetical protein Mb3350c 6 None None None 31794019 Common - hypothetical protein Mb2867c 20 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 31794420 Common secA1 preprotein translocase subunit SecA Mb3268c 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 31791224 Common - hypothetical protein Mb0048c 35 COG1695 COG1695, Predicted transcriptional regulators Transcription 31791563 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LUXR/UHPA-FAMILY) Mb0393 47 COG3903 COG3903, Predicted ATPase General function prediction only 31792493 Common hemK PROBABLE HEMK PROTEIN HOMOLOG HEMK Mb1332 219 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 31793384 Common - hypothetical protein Mb2228c 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 31794020 Common - PROBABLE CONSERVED TRANSMEMBRANE ALANINE RICH PROTEIN Mb2868 1 None None None 31791179 Common dnaN DNA polymerase III subunit beta Mb0002 213 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 31792407 Pathogen PE14 PE FAMILY PROTEIN Mb1246c 1 None None None 31793696 Common - hypothetical protein Mb2544c 22 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 31794696 Common - POSSIBLE COENZYME F420-DEPENDENT OXIDOREDUCTASE Mb3550c 56 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31793414 Common ptpA PHOSPHOTYROSINE PROTEIN PHOSPHATASE PTPA (PROTEIN-TYROSINE-PHOSPHATASE) (PTPase) (LMW PHOSPHATASE) Mb2258 138 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 31791189 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb0012 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 31793110 Common PPE35a PPE FAMILY PROTEIN Mb1953c 4 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791558 Common - hypothetical protein Mb0388c 1 None None None 31794872 Common - hypothetical protein Mb3727c 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 31793212 Common - CONSERVED HYPOTHETICAL PROTEIN [SECOND PART] Mb2055c 18 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 31794239 Common fadE22b PROBABLE ACYL-COA DEHYDROGENASE FADE22b [SECOND PART] Mb3087c 113 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31793487 Pathogen - HYPOTHETICAL GLYCINE RICH PROTEIN Mb2331c 1 None None None 31794066 Common rpsB 30S ribosomal protein S2 Mb2914c 228 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 31794477 Common nei PROBABLE ENDONUCLEASE VIII NEI Mb3325 165 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 31794811 Common fic POSSIBLE CELL FILAMENTATION PROTEIN FIC Mb3665c 39 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 31792522 Common glgB glycogen branching enzyme Mb1361c 155 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 31794213 Common - hypothetical protein Mb3061 5 COG1520 COG1520, FOG: WD40-like repeat Function unknown 31793096 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb1938 47 COG1950 COG1950, Predicted membrane protein Function unknown 31791386 Common trmB tRNA (guanine-N(7))-methyltransferase Mb0214c 169 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 31791611 Common - hypothetical protein Mb0441 68 COG2170 COG2170, Uncharacterized conserved protein Function unknown 31793431 Common - POSSIBLE FLAVOPROTEIN Mb2275 180 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 31792738 Common frdBC PROBABLE FUMARATE REDUCTASE [IRON-SULFUR SUBUNIT] FRDB and [MEMBRANE ANCHOR SUBUNIT] FRDC (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE) Mb1579 199 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 31795025 Pathogen - POSSIBLE MEMBRANE PROTEIN Mb3881 1 None None None 31792863 Common dsbF PROBABLE CONSERVED LIPOPROTEIN DSBF Mb1704 62 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 31794945 Common - CONSERVED HYPOTHETICAL PROTEIN [SECOND PART] Mb3801c 5 None None None 31792868 Common - Probable coiled-coil structural protein Mb1709 68 None None None 31792768 Common - Probable phiRv1 phage protein Mb1608c 45 COG3378 COG3378, Predicted ATPase General function prediction only 31794917 Pathogen - hypothetical protein Mb3773 1 None None None 31793237 Common - hypothetical protein Mb2080 81 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 31791739 Common pimB MANNOSYLTRANSFERASE PIMB Mb0572 189 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 31794083 Common rimM 16S rRNA-processing protein Mb2931c 107 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 31791950 Common - hypothetical protein Mb0785c 6 None None None 31793480 Common - hypothetical protein Mb2324 8 None None None 31792848 Common pks7 Probable polyketide synthase pks7 Mb1689 222 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31793215 Common - Conserved hypothetical protein Acg Mb2058 16 None None None 31791352 Common mce1F MCE-FAMILY PROTEIN MCE1F Mb0180 41 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31792876 Common lprJ PROBABLE LIPOPROTEIN LPRJ Mb1716 1 None None None 31792830 Common rplT 50S ribosomal protein L20 Mb1670 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 31794718 Common - hypothetical protein Mb3572c 26 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 31794593 Common - hypothetical protein Mb3446 7 None None None 31793436 Common - hypothetical protein Mb2280c 17 None None None 31791543 Common - hypothetical protein Mb0373c 31 COG4185 COG4185, Uncharacterized protein conserved in bacteria Function unknown 31794435 Common manA PROBABLE MANNOSE-6-PHOSPHATE ISOMERASE MANA (PHOSPHOMANNOSE ISOMERASE) (PHOSPHOMANNOISOMERASE) (PMI) (PHOSPHOHEXOISOMERASE) (PHOSPHOHEXOMUTASE) Mb3283c 42 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 31791659 Common - PROBABLE CONSERVED MEMBRANE PROTEIN Mb0489c 3 None None None 31791541 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb0371 125 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 31793028 Common - hypothetical protein Mb1869c 3 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31791213 Common - hypothetical protein Mb0037c 11 None None None 31793388 Pathogen - Probable conserved integral membrane protein Mb2232 1 None None None 31793638 Common clpX ATP-dependent protease ATP-binding subunit Mb2484c 221 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 31791466 Common esxG hypothetical protein Mb0295 1 None None None 31794230 Common nrdI ribonucleotide reductase stimulatory protein Mb3078c 36 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 31791860 Common mmpL5 PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL5 Mb0695c 80 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31792882 Common recN Probable DNA repair protein recN (Recombination protein N) Mb1722 198 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 31792506 Common - POSSIBLE TRANSPOSASE [SECOND PART] Mb1345c 38 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 31791903 Common rpsN 30S ribosomal protein S14 Mb0738 210 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 31793953 Common - hypothetical protein Mb2800c 6 None None None 31795034 Common - hypothetical protein Mb3890 13 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 31792413 Common - PROBABLE METHYLTRANSFERASE Mb1252c 97 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 31791365 Common - PROBABLE O-METHYLTRANSFERASE Mb0193 112 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 31793171 Common - hypothetical protein Mb2014c 38 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 31794533 Common PPE56a PPE FAMILY PROTEIN [FIRST PART] Mb3385c 9 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791267 Common - POSSIBLE METHYLTRANSFERASE/METHYLASE Mb0092 144 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31792728 Common glbN Probable hemoglobin glbN Mb1569c 28 COG2346 COG2346, Truncated hemoglobins General function prediction only 31794189 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C Mb3037c 42 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 31791403 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0231c 7 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 31792185 Common moeA1 PROBABLE MOLYBDOPTERIN BIOSYNTHESIS PROTEIN MOEA1 Mb1021 192 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 31792346 Common omt PROBABLE O-METHYLTRANSFERASE OMT Mb1184c 35 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31794763 Common - hypothetical protein Mb3617 28 COG1623 COG1623, Predicted nucleic-acid-binding protein (contains the HHH domain) General function prediction only 31792244 Pathogen - hypothetical protein Mb1082c 1 None None None 31792995 Pathogen PE20 PE FAMILY PROTEIN Mb1835 1 None None None 31793275 Common helY PROBABLE ATP-DEPENDENT DNA HELICASE HELY Mb2119c 113 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 31793537 Common - hypothetical protein Mb2381c 4 None None None 31793509 Common - PUTATIVE TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSORTER Mb2353c 247 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 31794772 Pathogen PE_PGRS59 PE-PGRS FAMILY PROTEIN Mb3626c 1 None None None 31794446 Common rmlD POSSIBLE DTDP-RHAMNOSE MODIFICATION PROTEIN RMLD Mb3294c 175 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 31791202 Pathogen - hypothetical protein Mb0026 1 None None None 31792996 Common PPE31 PPE FAMILY PROTEIN Mb1836 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31792104 Pathogen PE7 PE FAMILY PROTEIN Mb0940c 1 None None None 31793169 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb2012c 4 None None None 31792794 Common bcpB Probable peroxidoxin bcpB Mb1634c 212 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 31793336 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase Mb2180c 214 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 31794460 Common accD5 PROBABLE PROPIONYL-COA CARBOXYLASE BETA CHAIN 5 ACCD5 (PCCASE) (PROPANOYL-COA:CARBON DIOXIDE LIGASE) Mb3308 216 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 31793856 Common arsA PROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSA Mb2703 172 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 31794869 Common - hypothetical protein Mb3724 20 None None None 31792086 Common - hypothetical protein Mb0922c 9 None None None 31792288 Common phoH2 PROBABLE PHOH-LIKE PROTEIN PHOH2 (PHOSPHATE STARVATION-INDUCIBLE PROTEIN PSIH) Mb1125 198 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 31791833 Common fabD2 PUTATIVE MALONYL COA-ACYL CARRIER PROTEIN TRANSACYLASE FABD2 (MCT) Mb0668 2 None None None 31794207 Common fixA PROBABLE ELECTRON TRANSFER FLAVOPROTEIN (BETA-SUBUNIT) FIXA (BETA-ETF) (ELECTRON TRANSFER FLAVOPROTEIN SMALL SUBUNIT) (ETFSS) Mb3055c 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 31791732 Pathogen - hypothetical protein Mb0565c 1 COG5302 COG5302, Post-segregation antitoxin (ccd killing mechanism protein) encoded by the F plasmid General function prediction only 31794273 Common - hypothetical protein Mb3121c 38 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31791638 Common - hypothetical protein Mb0468 41 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 31792353 Common phhB pterin-4-alpha-carbinolamine dehydratase Mb1191c 58 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 31791940 Common mmsA PROBABLE METHYLMALONATE-SEMIALDEHYDE DEHYDROGENASE MMSA (METHYLMALONIC ACID SEMIALDEHYDE DEHYDROGENASE) (MMSDH) Mb0775c 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 31792701 Common - TDP-4-oxo-6-deoxy-D-glucose transaminase Mb1542c 196 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 31791249 Common - PROBABLE GLUTAMINE-TRANSPORT TRANSMEMBRANE PROTEIN ABC TRANSPORTER Mb0073 30 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 31793462 Common - hypothetical protein Mb2306 28 COG4908 COG4908, Uncharacterized protein containing a NRPS condensation (elongation) domain General function prediction only 31793831 Pathogen - hypothetical protein Mb2678c 1 None None None 31792179 Common - POSSIBLE CONSERVED EXPORTED PROTEIN Mb1015 50 COG5621 COG5621, Predicted secreted hydrolase General function prediction only 31794732 Common fadA6 acetyl-CoA acetyltransferase Mb3586c 186 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31793893 Common - POSSIBLE CONSERVED TRANSMEMBRANE ALANINE AND GLYCINE RICH PROTEIN Mb2740c 12 COG5479 COG5479, Uncharacterized protein potentially involved in peptidoglycan biosynthesis Cell envelope biogenesis, outer membrane 31791288 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0114 164 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 31793581 Common - hypothetical protein Mb2425 70 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 31792436 Pathogen PE_PGRS23 PE-PGRS FAMILY PROTEIN Mb1275c 1 None None None 31791685 Common cmaA2 CYCLOPROPANE-FATTY-ACYL-PHOSPHOLIPID SYNTHASE 2 CMAA2 (CYCLOPROPANE FATTY ACID SYNTHASE) (CFA SYNTHASE) (CYCLOPROPANE MYCOLIC ACID SYNTHASE 2) (MYCOLIC ACID TRANS-CYCLOPROPANE SYNTHETASE) Mb0515c 126 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 31792134 Common - short chain dehydrogenase Mb0970 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 31793644 Common lipP PROBABLE ESTERASE/LIPASE LIPP Mb2490 72 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 31793550 Common dnaJ2 PROBABLE CHAPERONE PROTEIN DNAJ2 Mb2394c 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 31792184 Common galU PROBABLE UTP--GLUCOSE-1-PHOSPHATE URIDYLYLTRANSFERASE GALU (UDP-GLUCOSE PYROPHOSPHORYLASE) (UDPGP) (ALPHA-D-GLUCOSYL-1-PHOSPHATE URIDYLYLTRANSFERASE) (URIDINE DIPHOSPHOGLUCOSE PYROPHOSPHORYLASE) Mb1020 203 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 31793651 Common glbO POSSIBLE GLOBIN (OXYGEN-BINDING PROTEIN) GLBO Mb2497 61 COG2346 COG2346, Truncated hemoglobins General function prediction only 31795006 Common - hypothetical protein Mb3862c 6 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31792634 Common secG preprotein translocase subunit SecG Mb1475 6 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 31792141 Common sucD succinyl-CoA synthetase subunit alpha Mb0977 213 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 31791440 Common aac AMINOGLYCOSIDE 2'-N-ACETYLTRANSFERASE AAC (AAC(2')-IC) Mb0268c 3 COG3393 COG3393, Predicted acetyltransferase General function prediction only 31794403 Common - short chain dehydrogenase Mb3251 229 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31791230 Common rpsF 30S ribosomal protein S6 Mb0054 204 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 31791431 Common nirD PROBABLE NITRITE REDUCTASE [NAD(P)H] SMALL SUBUNIT NIRD Mb0259 44 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 31791414 Common - SMALL SECRETED PROTEIN Mb0242c 3 None None None 31794559 Common - POSSIBLE CYCLASE Mb3411c 8 COG1657 SqhC, Squalene cyclase Lipid metabolism 31793938 Common dfrA PROBABLE DIHYDROFOLATE REDUCTASE DFRA (TETRAHYDROFOLATE DEHYDROGENASE) Mb2785c 145 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 31792371 Common fdxC PROBABLE FERREDOXIN FDXC Mb1210 137 COG1146 COG1146, Ferredoxin Energy production and conversion 31792116 Common pstC2 PHOSPHATE-TRANSPORT INTEGRAL MEMBRANE ABC TRANSPORTER PSTC2 Mb0952 222 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 31794409 Common - hypothetical protein Mb3257 161 COG1162 COG1162, Predicted GTPases General function prediction only 31793980 Pathogen - hypothetical protein Mb2827c 1 None None None 31791647 Common fadB2 3-hydroxybutyryl-CoA dehydrogenase Mb0477 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 31792338 Common mcr PROBABLE ALPHA-METHYLACYL-COA RACEMASE MCR (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) Mb1175 115 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 31794319 Common - PROBABLE RESPONSE REGULATOR Mb3167 12 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31793500 Common uspB PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER USPB Mb2344 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 31791976 Common - phosphoribosylformylglycinamidine synthase subunit PurS Mb0811 67 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 31794668 Common - CONSERVED HYPOTHETICAL MCE ASSOCIATED PROTEIN Mb3522c 3 None None None 31792048 Common fadB PROBABLE FATTY OXIDATION PROTEIN FADB Mb0883 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 31794458 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3306c 14 COG3428 COG3428, Predicted membrane protein Function unknown 31793369 Common - hypothetical protein Mb2213c 92 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 31791840 Common - hypothetical protein Mb0675c 2 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31794122 Common lppX PROBABLE CONSERVED LIPOPROTEIN LPPX Mb2970c 3 None None None 31791581 Common fadD30 acyl-CoA synthetase Mb0411 191 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792264 Common - hypothetical protein Mb1102 8 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 31791803 Common - POSSIBLE MEMBRANE PROTEIN Mb0637 2 None None None 31792709 Common - Probable methyltransferase Mb1550 171 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31792126 Common - hypothetical protein Mb0962c 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 31792963 Common - PROBABLE OXIDOREDUCTASE Mb1803 54 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 31794904 Common - hypothetical protein Mb3759 10 COG4402 COG4402, Uncharacterized protein conserved in bacteria Function unknown 31793994 Common - HYPOTHETICAL PROTEIN [FIRST PART] Mb2842c 3 None None None 31792697 Common - PROBABLE GLYCOSYLTRANSFERASE Mb1538 161 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 31791694 Common hemB delta-aminolevulinic acid dehydratase Mb0525 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 31792758 Pathogen - hypothetical protein Mb1598A 1 None None None 31791957 Common - short chain dehydrogenase Mb0792 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31793762 Common - hypothetical protein Mb2609c 102 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 31791729 Common - short chain dehydrogenase Mb0561c 212 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 31792795 Common trpE anthranilate synthase component I Mb1635 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 31793588 Common - hypothetical protein Mb2432c 93 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 31795012 Common pheA prephenate dehydratase Mb3868c 209 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 31792254 Common - hypothetical protein Mb1092c 120 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 31793561 Common mbtA BIFUNCTIONAL ENZYME MBTA: SALICYL-AMP LIGASE (SAL-AMP LIGASE) + SALICYL-S-ArCP SYNTHETASE Mb2405 218 COG1021 EntE, Peptide arylation enzymes Secondary metabolites biosynthesis, transport, and catabolism 31792072 Common serC phosphoserine aminotransferase Mb0908c 152 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 31793152 Common - hypothetical protein Mb1995c 28 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 31791909 Common rplO 50S ribosomal protein L15 Mb0744 204 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 31792449 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE TRANSPORT PROTEIN Mb1288c 101 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31792391 Pathogen esxL PUTATIVE ESAT-6 LIKE PROTEIN 4 Mb1230 1 None None None 31793975 Common - PROBABLE MEMBRANE PROTEIN Mb2822 1 None None None 31793184 Common - hypothetical protein Mb2027c 57 COG2187 COG2187, Uncharacterized protein conserved in bacteria Function unknown 31793892 Common lexA LexA repressor Mb2739 172 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 31792016 Common - POSSIBLE DEAMINASE Mb0851c 115 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 31794336 Common PPE70 PPE FAMILY PROTEIN Mb3184c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31794767 Pathogen PE_PGRS58 PE-PGRS FAMILY PROTEIN Mb3621c 1 None None None 31793734 Common - hypothetical protein Mb2581c 4 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 31794782 Common folK 2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE PYROPHOSPHOKINASE FOLK (7,8-DIHYDRO-6-HYDROXYMETHYLPTERIN-PYROPHOSPHOKINASE) (HPPK) (6-HYDROXYMETHYL-7,8-DIHYDROPTERIN PYROPHOSPHOKINASE) (PPPK) (2-AMINO-4-HYDROXY-6-HYDROXYMETHYLDIHYDROPTERIDINE DIPHOSPHO Mb3636c 178 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 31791258 Common - hypothetical protein Mb0083 9 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 31794745 Common bphC PUTATIVE BIPHENYL-2,3-DIOL 1,2-DIOXYGENASE BPHC (23OHBP OXYGENASE) (2,3-DIHYDROXYBIPHENYL DIOXYGENASE) (2,3-DIHYDROXYBIPHENYL 1,2-DIOXYGENASE) (DHBD) Mb3599c 25 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 31791663 Common lprQ PROBABLE CONSERVED LIPOPROTEIN LPRQ Mb0493 15 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 31791928 Pathogen PE_PGRS8 PE-PGRS FAMILY PROTEIN Mb0763 1 None None None 31792367 Common fbiC FO synthase Mb1206 83 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 31794623 Common - HYPOTHETICAL ALANINE AND VALINE RICH PROTEIN Mb3476c 1 None None None 31791588 Common pknG SERINE/THREONINE-PROTEIN KINASE PKNG (PROTEIN KINASE G) (STPK G) Mb0418c 131 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 31791849 Pathogen - hypothetical protein Mb0684 1 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31792488 Common thrC threonine synthase Mb1327 162 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 31791489 Common - hypothetical protein Mb0318c 8 None None None 31794249 Common ccrB camphor resistance protein CrcB Mb3097 54 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 31792532 Common cysM PROBABLE CYSTEINE SYNTHASE B CYSM (CSASE B) (O-acetylserine sulfhydrylase B) (O-acetylserine (Thiol)-lyase B) Mb1371 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 31794389 Common rhlE PROBABLE ATP-DEPENDENT RNA HELICASE RHLE Mb3237 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 31792174 Common moaB2 POSSIBLE PTERIN-4-ALPHA-CARBINOLAMINE DEHYDRATASE MOAB2 (PHS) (4-ALPHA-HYDROXY-TETRAHYDROPTERIN DEHYDRATASE) (PTERIN-4-A-CARBINOLAMINE DEHYDRATASE) (PHENYLALANINE HYDROXYLASE-STIMULATING PROTEIN) (PHS) (PTERIN CARBINOLAMINE DEHYDRATASE) (PCD) Mb1010 182 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 31794729 Common - POSSIBLE OXIDOREDUCTASE Mb3583 137 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 31791426 Common sdhA succinate dehydrogenase flavoprotein subunit Mb0254c 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 31794804 Common galE1 UDP-GLUCOSE 4-EPIMERASE GALE1 (GALACTOWALDENASE) (UDP-GALACTOSE 4-EPIMERASE) (URIDINE DIPHOSPHATE GALACTOSE 4-EPIMERASE) (URIDINE DIPHOSPHO-GALACTOSE 4-EPIMERASE) Mb3658c 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 31792742 Common mmpL6 PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL6 Mb1583 33 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31792984 Common - CONSERVED HYPOTHETICAL PRO-RICH PROTEASE Mb1824 26 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 31793401 Common glnE GLUTAMATE-AMMONIA-LIGASE ADENYLYLTRANSFERASE GLNE (Glutamine-synthetase adenylyltransferase) Mb2245c 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 31792544 Common - PROBABLE DRUGS-TRANSPORT TRANSMEMBRANE ATP-BINDING PROTEIN ABC TRANSPORTER Mb1383 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 31793848 Common - hypothetical protein Mb2695c 36 COG3253 COG3253, Uncharacterized conserved protein Function unknown 31791239 Common celA1 POSSIBLE CELLULASE CELA1 (ENDOGLUCANASE) (ENDO-1,4-BETA-GLUCANASE) (FI-CMCASE) (CARBOXYMETHYL CELLULASE) Mb0063 14 COG5297 CelA, Cellobiohydrolase A (1,4-beta-cellobiosidase A) Carbohydrate transport and metabolism 31793325 Common wag31 CONSERVED HYPOTHETICAL PROTEIN WAG31 Mb2169c 47 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 31791533 Common - hypothetical protein Mb0363c 6 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 31792477 Common cysD sulfate adenylyltransferase subunit 2 Mb1316 124 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 31793450 Pathogen - hypothetical protein Mb2294 1 None None None 31793023 Common - haloalkane dehalogenase Mb1864c 141 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31792894 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb1734 149 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 31791338 Common PE4 PE FAMILY PROTEIN Mb0165c 1 None None None 31791681 Common proC pyrroline-5-carboxylate reductase Mb0511 210 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 31792961 Common - hypothetical protein Mb1801 2 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 31793459 Common - Probable transcription regulator (lysR family) Mb2303c 171 COG0583 LysR, Transcriptional regulator Transcription 31794322 Common nuoB NADH dehydrogenase subunit B Mb3170 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 31791360 Common sigG RNA polymerase factor sigma-70 Mb0188c 112 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 31791961 Common ggtA PROBABLE BIFUNCTIONAL ACYLASE GGTA: CEPHALOSPORIN ACYLASE (GL-7ACA ACYLASE) + GAMMA-GLUTAMYLTRANSPEPTIDASE (GGT) Mb0796c 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 31792784 Common - hypothetical protein Mb1624c 3 None None None 31792154 Pathogen - hypothetical protein Mb0990c 1 None None None 31793873 Common suhB POSSIBLE EXTRAGENIC SUPPRESSOR PROTEIN SUHB Mb2720c 189 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 31794370 Common - hypothetical protein Mb3218 11 None None None 31793066 Common bfrA PROBABLE BACTERIOFERRITIN BFRA Mb1907 109 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 31794237 Common cyp136 PROBABLE CYTOCHROME P450 136 CYP136 Mb3085 77 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31794454 Common fadE25 PROBABLE ACYL-COA DEHYDROGENASE FADE25 Mb3302c 166 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31791641 Common lpd dihydrolipoamide dehydrogenase Mb0471 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 31791715 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III Mb0547c 231 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 31791480 Common - hypothetical protein Mb0309 3 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31791661 Common - hypothetical protein Mb0491c 7 None None None 31792039 Common - short chain dehydrogenase Mb0874c 233 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 31793803 Common - PROBABLE TRANSMEMBRANE PROTEIN Mb2650c 6 None None None 31791306 Common - hypothetical protein Mb0132 58 COG3281 Ble, Uncharacterized protein, probably involved in trehalose biosynthesis Carbohydrate transport and metabolism 31792242 Common - hypothetical protein Mb1080c 17 None None None 31793228 Common lipT Probable carboxylesterase LipT Mb2071c 91 COG2272 PnbA, Carboxylesterase type B Lipid metabolism 31794192 Common - hypothetical protein Mb3040c 18 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 31794920 Common - PUTATIVE EXCISIONASE Mb3776c 31 None None None 31791926 Pathogen - hypothetical protein Mb0761 1 None None None 31793424 Common acpP acyl carrier protein Mb2268 159 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31795038 Common - hypothetical protein Mb3894 1 None None None 31794538 Common - hypothetical protein Mb3390c 1 None None None 31791820 Common - hypothetical protein Mb0655 62 COG2030 MaoC, Acyl dehydratase Lipid metabolism 31792902 Common fadB3a PROBABLE 3-HYDROXYBUTYRYL-COA DEHYDROGENASE FADB3a [FIRST PART] (BETA-HYDROXYBUTYRYL-COA DEHYDROGENASE) (BHBD) Mb1742 156 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 31792845 Common argG argininosuccinate synthase Mb1686 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 31793690 Common - hypothetical protein Mb2538c 76 COG0433 COG0433, Predicted ATPase General function prediction only 31791463 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb0292 55 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 31792601 Common fmu PROBABLE FMU PROTEIN (SUN PROTEIN) Mb1442 196 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 31791359 Common - hypothetical protein Mb0187c 147 COG1741 COG1741, Pirin-related protein General function prediction only 31791850 Pathogen - POSSIBLE MEMBRANE PROTEIN Mb0685 1 None None None 31795031 Pathogen - POSSIBLE MEMBRANE PROTEIN Mb3887c 1 None None None 31792159 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0995 2 None None None 31791579 Common mmpL1a PROBABLE CONSERVED TRANSMEMBRANE TRANSPORT PROTEIN MMPL1A [FIRST PART] Mb0409c 67 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 31791900 Common rplN 50S ribosomal protein L14 Mb0735 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 31794587 Common - PROBABLE DIOXYGENASE Mb3440 47 COG2175 TauD, Probable taurine catabolism dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 31791945 Common phoP POSSIBLE TWO COMPONENT SYSTEM RESPONSE TRANSCRIPTIONAL POSITIVE REGULATOR PHOP Mb0780 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 31791660 Common - hypothetical protein Mb0490c 173 COG0388 COG0388, Predicted amidohydrolase General function prediction only 31793573 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN [SECOND PART] Mb2417 40 COG1297 COG1297, Predicted membrane protein Function unknown 31791292 Common - POSSIBLE DEHYDRATASE Mb0118 120 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 31791418 Pathogen - hypothetical protein Mb0246 1 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31791735 Common menC O-succinylbenzoate synthase Mb0568 30 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 31791742 Common - POSSIBLE BENZOQUINONE METHYLTRANSFERASE (METHYLASE) Mb0575c 78 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 31792217 Common - hypothetical protein Mb1054 178 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 31793519 Common cysE PROBABLE SERINE ACETYLTRANSFERASE CYSE (SAT) Mb2363 188 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 31793757 Common - hypothetical protein Mb2604 5 COG3427 COG3427, Uncharacterized conserved protein Function unknown 31792717 Common - hypothetical protein Mb1558 23 COG2128 COG2128, Uncharacterized conserved protein Function unknown 31794486 Common amiB1 PROBABLE AMIDASE AMIB1 (AMINOHYDROLASE) Mb3334c 149 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 31791888 Common rplW 50S ribosomal protein L23 Mb0723 129 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 31792111 Common - hypothetical protein Mb0947c 24 COG4195 COG4195, Phage-related replication protein General function prediction only 31792456 Common - ADENYLYL CYCLASE (ATP PYROPHOSPHATE-LYASE) (ADENYLATE CYCLASE) Mb1295 14 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31793743 Common - PROBABLE PROLINE AND GLYCINE RICH TRANSMEMBRANE PROTEIN Mb2590 5 COG5473 COG5473, Predicted integral membrane protein Function unknown 31793190 Common - hypothetical protein Mb2033 13 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31792642 Common tal transaldolase Mb1483c 128 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 31794999 Common pks2 POLYKETIDE SYNTHASE PKS2 Mb3855c 211 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794228 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ASNC-FAMILY) Mb3076c 39 COG1309 AcrR, Transcriptional regulator Transcription 31794663 Common lipF PROBABLE ESTERASE/LIPASE LIPF Mb3517c 112 COG0657 Aes, Esterase/lipase Lipid metabolism 31792237 Pathogen - hypothetical protein Mb1075c 1 None None None 31792614 Common uvrC excinuclease ABC subunit C Mb1455 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 31792097 Common - hypothetical protein Mb0933 6 None None None 31794143 Common pca pyruvate carboxylase Mb2991c 233 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 31791508 Common - hypothetical protein Mb0337c 7 COG1309 AcrR, Transcriptional regulator Transcription 31793597 Common - hypothetical protein Mb2441c 3 None None None 31794221 Common ctaD PROBABLE CYTOCHROME C OXIDASE POLYPEPTIDE I CTAD (CYTOCHROME AA3 SUBUNIT 1) Mb3069c 167 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 31792022 Pathogen PE_PGRS14 PE-PGRS FAMILY PROTEIN Mb0857c 1 COG5038 COG5038, Ca2+-dependent lipid-binding protein, contains C2 domain General function prediction only 31792558 Common - POSSIBLE MEMBRANE PROTEIN Mb1397c 5 None None None 31794241 Common ligB ATP-dependent DNA ligase Mb3089 105 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 31793890 Common - hypothetical protein Mb2737c 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 31791775 Common lprL POSSIBLE MCE-FAMILY LIPOPROTEIN LPRL (MCE-FAMILY LIPOPROTEIN MCE2E) Mb0609 9 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31792578 Common carB carbamoyl phosphate synthase large subunit Mb1419 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 31793475 Pathogen - hypothetical protein Mb2319 1 None None None 31791389 Common pckA phosphoenolpyruvate carboxykinase Mb0217 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 31791754 Common - hypothetical protein Mb0587c 1 None None None 31792009 Common phoY2 PROBABLE PHOSPHATE-TRANSPORT SYSTEM TRANSCRIPTIONAL REGULATORY PROTEIN PHOY2 Mb0844c 190 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 31794376 Common nudC NADH pyrophosphatase Mb3224c 105 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 31792206 Common rplY 50S ribosomal protein L25/general stress protein Ctc Mb1043c 65 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 31794496 Common cdd cytidine deaminase Mb3344c 116 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 31792090 Common prrB TWO COMPONENT SENSOR HISTIDINE KINASE PRRB Mb0926c 193 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 31792301 Common xseA exodeoxyribonuclease VII large subunit Mb1138c 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 31794414 Common - hypothetical protein Mb3262c 28 None None None 31792313 Pathogen - hypothetical protein Mb1150c 1 None None None 31794525 Common metX homoserine O-acetyltransferase Mb3373 128 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 31792555 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb1394 2 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 31792132 Common - PROBABLE MONOOXYGENASE Mb0968c 38 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 31794913 Common ctpJ PUTATIVE CATION TRANSPORTER P-TYPE ATPASE CTPJ Mb3769c 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 31794303 Pathogen - hypothetical protein Mb3151c 1 None None None 31793590 Common - hypothetical protein Mb2434c 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 31794097 Common ftsY PROBABLE CELL DIVISION PROTEIN FTSY Mb2945c 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 31795089 Common - hypothetical protein Mb3947c 11 None None None 31794350 Common - PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR/ACRR-FAMILY) Mb3198c 62 COG1309 AcrR, Transcriptional regulator Transcription 31791422 Common fadE5 PROBABLE ACYL-COA DEHYDROGENASE FADE5 Mb0250c 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31793641 Common clpP2 ATP-dependent Clp protease proteolytic subunit Mb2487c 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 31793268 Common - hypothetical protein Mb2112 1 None None None 31794329 Common nuoI NADH dehydrogenase subunit I Mb3177 193 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 31792334 Common - hypothetical protein Mb1171c 29 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 31794995 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb3851 1 None None None 31794284 Common prfB peptide chain release factor 2 Mb3132c 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 31794440 Common whiB2 PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB2 Mb3288c 19 None None None 31791205 Pathogen - hypothetical protein Mb0029 1 None None None 31792923 Common - HYPOTHETICAL MEMBRANE PROTEIN Mb1764c 18 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 31793346 Common - hypothetical protein Mb2190c 133 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 31794173 Common - POSSIBLE ALANINE RICH DEHYDROGENASE Mb3021 47 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794167 Common - hypothetical protein Mb3015 16 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 31791719 Common - PROBABLE INTEGRAL MEMBRANE PROTEIN Mb0551c 1 None None None 31793869 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase Mb2716c 176 COG0756 Dut, dUTPase Nucleotide transport and metabolism 31794006 Pathogen - hypothetical protein Mb2854c 1 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 31794892 Common - POSSIBLE FATTY ACID SYNTHASE Mb3747 128 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 31793619 Pathogen - hypothetical protein Mb2465 1 None None None 31794511 Pathogen - hypothetical protein Mb3359c 1 None None None 31793663 Common - hypothetical protein Mb2509c 28 None None None 31791510 Common - hypothetical protein Mb0339 9 None None None 31793098 Common aao PUTATIVE D-AMINO ACID OXIDASE AAO Mb1940c 11 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 31791493 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb0322c 3 None None None 31794974 Common pks13 POLYKETIDE SYNTHASE PKS13 Mb3830c 210 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31792195 Pathogen - PROBABLE MEMBRANE PROTEIN Mb1031c 1 None None None 31793968 Common - POSSIBLE RESOLVASE Mb2815c 21 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 31792681 Common - hypothetical protein Mb1522c 10 None None None 31791378 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb0206 1 None None None 31792060 Pathogen PE_PGRS15 PE-PGRS FAMILY PROTEIN Mb0896c 1 None None None 31791435 Pathogen - hypothetical protein Mb0263 1 None None None 31791767 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0600c 8 COG0392 COG0392, Predicted integral membrane protein Function unknown 31794116 Common papA5 acyltransferase PapA5 Mb2964 6 None None None 31793907 Common - hypothetical protein Mb2754c 5 None None None 31794254 Common - hypothetical protein Mb3102c 108 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 31792294 Common - hypothetical protein Mb1131c 140 COG0628 PerM, Predicted permease General function prediction only 31792270 Common metB cystathionine gamma-synthase Mb1108 209 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 31793055 Common - short chain dehydrogenase Mb1896c 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 31791344 Common fadD5 acyl-CoA synthetase Mb0172 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793357 Common - hypothetical protein Mb2201c 9 None None None 31793442 Common - short chain dehydrogenase Mb2286 122 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31794619 Common rpsI 30S ribosomal protein S9 Mb3472c 216 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 31793313 Common - hypothetical protein Mb2157c 18 None None None 31793078 Common - hypothetical protein Mb1919 1 None None None 31794139 Common - PROBABLE INTEGRAL MEMBRANE PROTEIN Mb2987 15 COG0701 COG0701, Predicted permeases General function prediction only 31793631 Common rpfE PROBABLE RESUSCITATION-PROMOTING FACTOR RPFE Mb2477c 12 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 31794597 Common whiB3 TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB3 Mb3450 19 None None None 31793826 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ARSR-FAMILY) Mb2673c 32 COG0640 ArsR, Predicted transcriptional regulators Transcription 31794025 Common cobB cobyrinic acid a,c-diamide synthase Mb2873c 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 31792002 Common sseC2 CONSERVED HYPOTHETICAL PROTEIN SSEC2 Mb0837c 10 None None None 31793956 Common aldb SECRETED L-ALANINE DEHYDROGENASE ALDb [SECOND PART] (40 KDA ANTIGEN) (TB43) Mb2803 166 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 31791835 Common rplJ 50S ribosomal protein L10 Mb0670 205 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 31795048 Common esxB 10 KDA CULTURE FILTRATE ANTIGEN LHP (CFP10) Mb3904 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31793448 Pathogen - hypothetical protein Mb2292c 1 None None None 31793253 Common cobK cobalt-precorrin-6x reductase Mb2096c 74 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 31791986 Common cfp29 29 KDa ANTIGEN CFP29 Mb0821c 17 COG1659 COG1659, Uncharacterized protein, linocin/CFP29 homolog Function unknown 31792950 Common - hypothetical protein Mb1791 28 None None None 31794400 Common - POSSIBLE ANTI-SIGMA FACTOR Mb3248c 9 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 31793361 Common - hypothetical protein Mb2205c 3 None None None 31794366 Common - CONSERVED HYPOTHETICAL ALANINE AND PROLINE-RICH PROTEIN Mb3214 9 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31795095 Common - hypothetical protein Mb3953c 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 31792911 Common - PROBABLE HYDROLASE Mb1752 50 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 31793823 Common dedA POSSIBLE TRANSMEMBRANE PROTEIN DEDA Mb2670 117 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 31794197 Common esxR PUTATIVE SECRETED ESAT-6 LIKE PROTEIN 9 TB10.3 Mb3045c 1 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31791624 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb0454c 35 COG3752 COG3752, Predicted membrane protein Function unknown 31791446 Pathogen - hypothetical protein Mb0274c 1 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 31791196 Common - hypothetical protein Mb0019c 45 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 31791593 Common thiO POSSIBLE THIAMINE BIOSYNTHESIS OXIDOREDUCTASE THIO Mb0423 99 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 31791845 Pathogen - hypothetical protein Mb0680c 1 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31791524 Common ansP2 POSSIBLE L-ASPARAGINE PERMEASE ANSP2 (L-ASPARAGINE TRANSPORT PROTEIN) Mb0354c 171 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 31792772 Common - Probable phiRv1 integrase Mb1612c 69 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 31793484 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb2328 1 COG0398 COG0398, Uncharacterized conserved protein Function unknown 31791871 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Mb0706 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31793309 Common - short chain dehydrogenase Mb2153c 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 31793610 Common PPE41 PPE FAMILY PROTEIN Mb2456c 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31793786 Common - hypothetical protein Mb2633 2 COG4691 StbC, Plasmid stability protein General function prediction only 31793707 Pathogen - hypothetical protein Mb2555 1 None None None 31793185 Common - hypothetical protein Mb2028c 68 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 31793923 Common - hypothetical protein Mb2770 16 COG1359 COG1359, Uncharacterized conserved protein Function unknown 31795029 Common ethR TRANSCRIPTIONAL REGULATORY REPRESSOR PROTEIN (TETR-FAMILY) ETHR Mb3885 22 COG1309 AcrR, Transcriptional regulator Transcription 31792498 Common atpE F0F1 ATP synthase subunit C Mb1337 2 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 31794565 Common - hypothetical protein Mb3417c 3 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 31793600 Common nadD nicotinic acid mononucleotide adenyltransferase Mb2444c 182 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 31794316 Common fadE23 PROBABLE ACYL-CoA DEHYDROGENASE FADE23 Mb3164 152 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31794847 Common - PUTATIVE HYDROLASE Mb3701c 176 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 31793851 Common echA15 enoyl-CoA hydratase Mb2698 163 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31793510 Common - hypothetical protein Mb2354 41 COG1846 MarR, Transcriptional regulators Transcription 31794128 Common - POSSIBLE METHYLTRANSFERASE (METHYLASE) Mb2976 133 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 31791790 Common - hypothetical protein Mb0624 3 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 31793091 Common - hypothetical protein Mb1933 15 COG0011 COG0011, Uncharacterized conserved protein Function unknown 31793935 Common hsdS POSSIBLE TYPE I RESTRICTION/MODIFICATION SYSTEM SPECIFICITY DETERMINANT HSDS (S PROTEIN) Mb2782c 40 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 31793744 Common - hypothetical protein Mb2591 2 None None None 31791392 Common fadD4 acyl-CoA synthetase Mb0220 213 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792355 Common narG PROBABLE RESPIRATORY NITRATE REDUCTASE (ALPHA CHAIN) NARG Mb1193 112 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 31792425 Common - hypothetical protein Mb1264c 122 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 31794584 Common - hypothetical protein Mb3437c 8 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 31792257 Common - hypothetical protein Mb1095 10 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 31792466 Common lprB PUTATIVE LIPOPROTEIN LPRB Mb1305 3 None None None 31794347 Common aofH PROBABLE FLAVIN-CONTAINING MONOAMINE OXIDASE AOFH (AMINE OXIDASE) (MAO) Mb3195 39 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 31794799 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb3653c 39 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 31793302 Common hisE phosphoribosyl-ATP pyrophosphatase Mb2146c 49 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 31794507 Common moaA3 PROBABLE MOLYBDENUM COFACTOR BIOSYNTHESIS PROTEIN A MOAA1 Mb3355c 204 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 31793041 Common ureF Urease accessory protein uref Mb1882 18 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 31793350 Common - hypothetical protein Mb2194c 2 None None None 31795045 Common - hypothetical protein Mb3901 27 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 31792428 Common lpqY PROBABLE SUGAR-BINDING LIPOPROTEIN LPQY Mb1267 68 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 31792652 Common - PROBABLE UNIDENTIFIED ANTIBIOTIC-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER Mb1493c 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 31794832 Common - hypothetical protein Mb3686c 9 None None None 31792044 Common - hypothetical protein Mb0879 6 None None None 31792959 Common - hypothetical protein Mb1799 3 COG2234 Iap, Predicted aminopeptidases General function prediction only 31794161 Common mutT1 POSSIBLE HYDROLASE MUTT1 Mb3009 33 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 31794518 Pathogen - HYPOTHETICAL PROLINE RICH PROTEIN Mb3366c 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 31794033 Common nicT POSSIBLE NICKEL-TRANSPORT INTEGRAL MEMBRANE PROTEIN NICT Mb2881 37 COG3376 HoxN, High-affinity nickel permease Inorganic ion transport and metabolism 31792626 Common - PROBABLE DEHYDROGENASE Mb1467 47 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 31794297 Pathogen - hypothetical protein Mb3145 1 None None None 31791665 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0495 80 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 31794102 Common rnc ribonuclease III Mb2950c 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 31792710 Common - Probable glycosyltransferase Mb1551 32 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 31792165 Common - hypothetical protein Mb1001c 35 None None None 31792081 Common - hypothetical protein Mb0917c 26 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31791476 Pathogen PE_PGRS5 PE-PGRS FAMILY PROTEIN Mb0305 1 None None None 31793128 Common - POSSIBLE MONOOXYGENASE Mb1971 69 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31793849 Common hemY protoporphyrinogen oxidase Mb2696c 53 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 31793915 Common - CONSERVED HYPOTHETICAL ARGININE RICH PROTEIN [SECOND PART] Mb2762c 3 None None None 31792590 Pathogen PE_PGRS25 PE-PGRS FAMILY PROTEIN Mb1431c 1 COG5164 SPT5, Transcription elongation factor Transcription 31794937 Common - hypothetical protein Mb3793c 25 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31791855 Common lpqP POSSIBLE CONSERVED LIPOPROTEIN LPQP Mb0690 49 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 31794267 Common - hypothetical protein Mb3115 28 None None None 31792970 Common malQ PROBABLE 4-ALPHA-GLUCANOTRANSFERASE MALQ (Amylomaltase) (Disproportionating enzyme) (D-enzyme) Mb1810c 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 31791461 Common - hypothetical protein Mb0290 66 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 31793705 Common fas PROBABLE FATTY ACID SYNTHASE FAS (FATTY ACID SYNTHETASE) Mb2553c 210 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 31794549 Common spoU PROBABLE tRNA/rRNA METHYLASE SPOU (tRNA/rRNA METHYLTRANSFERASE) Mb3401 156 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 31794211 Common - hypothetical protein Mb3059 3 None None None 31794874 Common - hypothetical protein Mb3729c 104 COG1262 COG1262, Uncharacterized conserved protein Function unknown 31793210 Common - hypothetical protein Mb2053c 11 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 31791657 Common - POSSIBLE CONSERVED SECRETED PROTEIN Mb0487 3 None None None 31793901 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE ALANINE AND VALINE AND LEUCINE RICH PROTEIN Mb2748c 6 None None None 31795010 Common - hypothetical protein Mb3866 45 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 31795093 Common - HYPOTHETICAL PROTEIN SIMILAR TO JAG PROTEIN Mb3951c 29 COG1847 Jag, Predicted RNA-binding protein General function prediction only 31793541 Common era GTP-binding protein Era Mb2385c 219 COG1159 Era, GTPase General function prediction only 31793218 Common - hypothetical protein Mb2061 8 COG3832 COG3832, Uncharacterized conserved protein Function unknown 31791556 Common secE2 POSSIBLE PROTEIN TRANSPORT PROTEIN SECE2 Mb0386 9 COG3360 COG3360, Uncharacterized conserved protein Function unknown 31791367 Common ilvD dihydroxy-acid dehydratase Mb0195c 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 31792411 Common - PROBABLE TETRONASIN-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER Mb1250c 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 31793982 Pathogen - POSSIBLE MEMBRANE PROTEIN Mb2829 1 None None None 31794960 Common - hypothetical protein Mb3816c 27 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31792468 Common - hypothetical protein Mb1307c 69 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 31793348 Common - hypothetical protein Mb2192 6 COG0456 RimI, Acetyltransferases General function prediction only 31792854 Common - MACROLIDE-TRANSPORT ATP-BINDING PROTEIN ABC TRANSPORTER Mb1695c 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 31793572 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN [FIRST PART] Mb2416 18 COG1297 COG1297, Predicted membrane protein Function unknown 31794639 Common - hypothetical protein Mb3492 10 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 31794187 Common pfkA 6-phosphofructokinase Mb3035c 161 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 31792865 Common fadE16 POSSIBLE ACYL-COA DEHYDROGENASE FADE16 Mb1706 146 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31791195 Common ppp POSSIBLE SERINE/THREONINE PHOSPHATASE PPP Mb0018c 133 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 31793334 Common ftsW FtsW-like protein FtsW Mb2178c 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 31791545 Common - hypothetical protein Mb0375c 31 COG3552 CoxE, Protein containing von Willebrand factor type A (vWA) domain General function prediction only 31793788 Common - hypothetical protein Mb2635c 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 31794919 Common - hypothetical protein Mb3775c 15 None None None 31791721 Common - PROBABLE DOLICHYL-PHOSPHATE SUGAR SYNTHASE (DOLICHOL-PHOSPHATE SUGAR SYNTHETASE) (DOLICHOL-PHOSPHATE SUGAR TRANSFERASE) (SUGAR PHOSPHORYLDOLICHOL SYNTHASE) Mb0553 149 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 31793668 Pathogen - HYPOTHETICAL ALANINE RICH PROTEIN Mb2516c 1 None None None 31792874 Common - 3-methyladenine DNA glycosylase Mb1714 74 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 31793386 Common cobT nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Mb2230 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 31793162 Pathogen PE_PGRS35 PE-PGRS FAMILY PROTEIN Mb2005 1 None None None 31793021 Pathogen - hypothetical protein Mb1862 1 None None None 31793689 Common - PUTATIVE SHORT-CHAIN TYPE DEHYDROGENASE/REDUCTASE Mb2537 220 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 31792993 Common - hypothetical protein Mb1833c 1 None None None 31793277 Common tatA twin argininte translocase protein A Mb2121c 62 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 31794040 Pathogen - hypothetical protein Mb2888 1 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31791640 Common - PROBABLE TRANSMEMBRANE PROTEIN Mb0470 1 None None None 31792925 Common narK2 POSSIBLE NITRATE/NITRITE TRANSPORTER NARK2 Mb1766c 68 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 31793359 Common - Probable conserved integral membrane protein Mb2203 12 COG5650 COG5650, Predicted integral membrane protein Function unknown 31791286 Pathogen - hypothetical protein Mb0112c 1 None None None 31793352 Common - Possible conserved integral membrane protein Mb2196 17 None None None 31791468 Common - hypothetical protein Mb0297 3 None None None 31794686 Common - hypothetical protein Mb3540c 50 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 31794887 Common recR recombination protein RecR Mb3742c 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 31794184 Common - POSSIBLE OXIDOREDUCTASE Mb3032c 76 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 31794615 Common - hypothetical protein Mb3468 5 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 31794590 Common choD PROBABLE CHOLESTEROL OXIDASE PRECURSOR CHOD (CHOLESTEROL-O2 OXIDOREDUCTASE) Mb3443c 65 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 31792703 Common - hypothetical protein Mb1544 1 None None None 31792269 Common pra Probable Proline-rich antigen homolog pra Mb1107 6 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 31793266 Pathogen - hypothetical protein Mb2109 1 None None None 31791727 Common pitA PROBABLE LOW-AFFINITY INORGANIC PHOSPHATE TRANSPORTER INTEGRAL MEMBRANE PROTEIN PITA Mb0559c 169 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 31793102 Common furA FERRIC UPTAKE REGULATION PROTEIN FURA (FUR) Mb1944c 151 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 31791478 Common - hypothetical protein Mb0307 2 None None None 31792739 Pathogen frdD fumarate reductase subunit D Mb1580 1 COG3080 FrdD, Fumarate reductase subunit D Energy production and conversion 31793955 Common alda SECRETED L-ALANINE DEHYDROGENASE ALDa [FIRST PART] (40 KDA ANTIGEN) (TB43) Mb2802 164 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 31792106 Common - hypothetical protein Mb0942 20 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 31792592 Pathogen - hypothetical protein Mb1433c 1 None None None 31791350 Common mce1D MCE-FAMILY PROTEIN MCE1D Mb0178 6 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31791265 Common hycE POSSIBLE FORMATE HYDROGENASE HYCQ (FHL) Mb0090 192 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 31791253 Pathogen - PROBABLE MEMBRANE PROTEIN Mb0078c 1 None None None 31792012 Common desA1 PROBABLE ACYL-[ACYL-CARRIER PROTEIN] DESATURASE DESA1 (ACYL-[ACP] DESATURASE) (STEAROYL-ACP DESATURASE) (PROTEIN DES) Mb0847c 9 None None None 31793173 Pathogen - hypothetical protein Mb2016c 1 None None None 31794516 Common sugI PROBABLE SUGAR-TRANSPORT INTEGRAL MEMBRANE PROTEIN SUGI Mb3364 78 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31792736 Common plsB1 glycerol-3-phosphate acyltransferase Mb1577 46 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 31791405 Common - PROBABLE INTEGRAL MEMBRANE ACYLTRANSFERASE Mb0233 58 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 31794050 Common mpb83 CELL SURFACE LIPOPROTEIN MPB83 (LIPOPROTEIN P23) Mb2898 66 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 31791913 Common fucA L-fuculose-phosphate aldolase Mb0748c 149 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 31793371 Common trpD anthranilate phosphoribosyltransferase Mb2215c 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 31791517 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0346c 12 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 31793963 Common - CONSERVED HYPOTHETICAL ALANINE RICH PROTEIN Mb2810 18 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 31793846 Common - hypothetical protein Mb2693 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 31792053 Common mog PUTATIVE MOLYBDOPTERIN BIOSYNTHESIS MOG PROTEIN Mb0889 181 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 31793294 Common - hypothetical protein Mb2138 6 None None None 31794342 Common - hypothetical protein Mb3190c 3 None None None 31791316 Common - hypothetical protein Mb0143 5 None None None 31794806 Common - PUTATIVE TRANSPOSASE Mb3660 10 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 31791605 Common xthA PROBABLE EXODEOXYRIBONUCLEASE III PROTEIN XTHA (EXONUCLEASE III) (EXO III) (AP ENDONUCLEASE VI) Mb0435c 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 31793944 Pathogen PE27 PE FAMILY PROTEIN Mb2791c 1 None None None 31793143 Pathogen - hypothetical protein Mb1986c 1 None None None 31794670 Common mce4F MCE-FAMILY PROTEIN MCE4F Mb3524c 22 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 31793117 Common fadD31 acyl-CoA synthetase Mb1960 191 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793676 Common pdhB PROBABLE PYRUVATE DEHYDROGENASE E1 COMPONENT (BETA SUBUNIT) PDHB (PYRUVATE DECARBOXYLASE) (PYRUVATE DEHYDROGENASE) (PYRUVIC DEHYDROGENASE) Mb2524c 207 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 31791955 Common - hypothetical protein Mb0790c 3 COG1309 AcrR, Transcriptional regulator Transcription 31792916 Common - hypothetical protein Mb1757c 5 None None None 31795080 Common pcnA POLY(A) POLYMERASE PCNA (POLYNUCLEOTIDE ADENYLYLTRANSFERASE) (NTP POLYMERASE) (RNA ADENYLATING ENZYME) (POLY(A) POLYMERASE) Mb3937c 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 31792979 Pathogen PE19 PE FAMILY PROTEIN Mb1819 1 None None None 31794752 Common - TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY LACI-FAMILY) Mb3606c 120 COG1609 PurR, Transcriptional regulators Transcription 31791491 Common - CONSERVED HYPOTHETICAL PROLINE AND THREONINE RICH PROTEIN Mb0320 34 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 31793622 Common rpmA 50S ribosomal protein L27 Mb2468c 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 31793776 Common ruvB Holliday junction DNA helicase B Mb2623c 224 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 31794946 Pathogen - CONSERVED HYPOTHETICAL PROTEIN [FIRST PART] Mb3802c 1 None None None 31791346 Common yrbE1B CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE1B Mb0174 15 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 31794727 Common - POSSIBLE COA-TRANSFERASE (ALPHA SUBUNIT) Mb3581 68 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 31793888 Common - hypothetical protein Mb2735 53 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 31794205 Common - hypothetical protein Mb3053c 66 COG3176 COG3176, Putative hemolysin General function prediction only 31794395 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb3243c 4 None None None 31791881 Common - PROBABLE DEHYDROGENASE Mb0716 87 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 31794218 Common - hypothetical protein Mb3066c 30 None None None 31793087 Common - POSSIBLE DEHYDROGENASE [FIRST PART] Mb1928 192 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 31791760 Pathogen PE_PGRS7 PE-PGRS FAMILY PROTEIN Mb0593c 1 None None None 31794775 Common lysS lysyl-tRNA synthetase Mb3629c 247 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 31791269 Common mtn PROBABLE BIFUNCTIONAL MTA/SAH NUCLEOSIDASE MTN: 5'-METHYLTHIOADENOSINE NUCLEOSIDASE + S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE Mb0094 93 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 31793258 Pathogen - hypothetical protein Mb2101c 1 None None None 31791376 Common - PROBABLE ZINC METALLOPROTEASE Mb0204c 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 31793382 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb2226 1 None None None 31793579 Pathogen - hypothetical protein Mb2423 1 None None None 31794057 Common cdsA PROBABLE INTEGRAL MEMBRANE PHOSPHATIDATE CYTIDYLYLTRANSFERASE CDSA (CDP-DIGLYCERIDE SYNTHETASE) (CDP-DIGLYCERIDE PYROPHOSPHORYLASE) (CDP-DIACYLGLYCEROL SYNTHASE) (CDS) (CTP:PHOSPHATIDATE CYTIDYLYLTRANSFERASE) (CDP-DAG SYNTHASE) (CDP-DG SYNTHETASE) Mb2905c 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 31793771 Common secD preprotein translocase subunit SecD Mb2618c 201 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 31794757 Common cysS cysteinyl-tRNA synthetase Mb3611c 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31794909 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3764 25 COG2966 COG2966, Uncharacterized conserved protein Function unknown 31791918 Common secY preprotein translocase subunit SecY Mb0753 237 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 31792208 Common prsA ribose-phosphate pyrophosphokinase Mb1045c 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 31793727 Pathogen lppB PROBABLE CONSERVED LIPOPROTEIN LPPB Mb2574 1 None None None 31794015 Common rbfA ribosome-binding factor A Mb2863c 43 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 31794779 Common - CONSERVED HYPOTHETICAL ALANINE AND LEUCINE RICH PROTEIN Mb3633c 42 COG5495 COG5495, Uncharacterized conserved protein Function unknown 31793609 Common ahpD ALKYL HYDROPEROXIDE REDUCTASE D PROTEIN AHPD (ALKYL HYDROPEROXIDASE D) Mb2455 27 COG2128 COG2128, Uncharacterized conserved protein Function unknown 31793138 Pathogen lppG POSSIBLE LIPOPROTEIN Mb1981c 1 None None None 31794789 Pathogen - hypothetical protein Mb3643c 1 None None None 31795069 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb3925c 8 None None None 31792801 Common - hypothetical membrane protein Mb1641 10 COG2314 XynA, Predicted membrane protein Function unknown 31791442 Common - hypothetical protein Mb0270c 97 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 31794017 Common - hypothetical protein Mb2865c 11 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 31794677 Common yrbE4A CONSERVED HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN YRBE4A Mb3531c 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 31791618 Common groEL chaperonin GroEL Mb0448 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 31792068 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (POSSIBLY MARR-FAMILY) Mb0904 30 COG1846 MarR, Transcriptional regulators Transcription 31791565 Common purT phosphoribosylglycinamide formyltransferase 2 Mb0395 100 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 31794630 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb3483 44 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 31793080 Common - hypothetical protein Mb1921c 12 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31791222 Common - POSSIBLE HYDROLASE Mb0046c 130 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31793503 Common rocE PROBABLE CATIONIC AMINO ACID TRANSPORT INTEGRAL MEMBRANE PROTEIN ROCE Mb2347c 169 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 31794260 Pathogen - hypothetical protein Mb3108 2 COG4914 COG4914, Predicted nucleotidyltransferase General function prediction only 31793412 Common cobC hypothetical protein Mb2256c 175 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 31793864 Common ceoC TRK SYSTEM POTASSIUM UPTAKE PROTEIN CEOC Mb2711 129 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 31791229 Common - hypothetical protein Mb0053 53 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 31793838 Common - truncated IS1081 transposase Mb2685 77 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 31791240 Common - POSSIBLE OXIDOREDUCTASE Mb0064 44 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 31793658 Common - putative ABC transporter ATP-binding protein Mb2504c 245 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 31793599 Common - hypothetical protein Mb2443c 150 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 31792482 Common - hypothetical protein Mb1321c 39 COG4325 COG4325, Predicted membrane protein Function unknown 31791321 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0148c 77 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 31793534 Common glyS glycyl-tRNA synthetase Mb2378c 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 31792759 Pathogen - Probable phiRV1 phage protein Mb1599 1 None None None 31793235 Common - hypothetical protein Mb2078c 94 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 31794581 Common - PROBABLE HYDROLASE Mb3433 82 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 31793485 Common - POSSIBLE CONSERVED MEMBRANE PROTEIN Mb2329 2 COG0398 COG0398, Uncharacterized conserved protein Function unknown 31794081 Common lppW PROBABLE CONSERVED ALANINE RICH LIPOPROTEIN LPPW Mb2929 7 None None None 31793154 Common - hypothetical protein Mb1997c 2 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31793679 Common - POSSIBLE OXIDASE REGULATORY-RELATED PROTEIN Mb2527c 79 COG2030 MaoC, Acyl dehydratase Lipid metabolism 31792262 Common echA9 enoyl-CoA hydratase Mb1100c 135 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 31793795 Common pimA ALPHA-MANNOSYLTRANSFERASE PIMA Mb2642c 185 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 31791274 Common PPE1 PPE FAMILY PROTEIN Mb0099 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791907 Common rpsE 30S ribosomal protein S5 Mb0742 240 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 31792766 Pathogen - Probable phiRv1 phage protein Mb1606c 1 None None None 31792454 Common - HYPOTHETICAL HIT-LIKE PROTEIN Mb1293c 192 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 31794101 Common fpg formamidopyrimidine-DNA glycosylase Mb2949c 180 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 31793037 Common - hypothetical protein Mb1878 61 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 31794247 Common pgmA phosphoglucomutase Mb3095c 211 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 31792018 Common - hypothetical protein Mb0853 29 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 31793592 Common - hypothetical protein Mb2436c 18 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 31791809 Common - hypothetical protein Mb0643 12 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 31792508 Common - hypothetical protein Mb1347c 129 COG2096 COG2096, Uncharacterized conserved protein Function unknown 31791420 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Mb0248c 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31794722 Common fadA5 acetyl-CoA acetyltransferase Mb3576 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 31793323 Common - hypothetical protein Mb2167 75 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 31794437 Common manB phosphomannomutase/phosphoglucomutase Mb3285c 240 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 31792447 Common - PROBABLE ACYLTRANSFERASE Mb1286 41 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 31791815 Common - POSSIBLE EXPORTED PROTEIN Mb0650c 2 None None None 31793223 Common - Probable sugar-transport integral membrane protein ABC transporter Mb2066c 182 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 31795008 Common serS seryl-tRNA synthetase Mb3864c 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 31792398 Common - hypothetical protein Mb1237 111 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 31791567 Common metZ O-succinylhomoserine sulfhydrylase Mb0397 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 31793584 Common - hypothetical protein Mb2428 11 None None None 31794064 Common amiC amidase Mb2912c 211 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 31792828 Common infC translation initiation factor IF-3 Mb1668 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 31792030 Common - PROBABLE CONSERVED INTEGRAL MEMBRANE PROTEIN Mb0865 4 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 31792756 Common bioD dithiobiotin synthetase Mb1597 7 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 31792968 Common - HYPOTHETICAL INTEGRAL MEMBRANE PROTEIN Mb1808c 3 None None None 31794621 Common esxT hypothetical protein Mb3474c 2 COG4842 COG4842, Uncharacterized protein conserved in bacteria Function unknown 31792252 Common - hypothetical protein Mb1090 112 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 31791847 Common atsD POSSIBLE ARYLSULFATASE ATSD (ARYL-SULFATE SULPHOHYDROLASE) (ARYLSULPHATASE) Mb0682 69 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 31793050 Common apa ALANINE AND PROLINE RICH SECRETED PROTEIN APA (FIBRONECTIN ATTACHMENT PROTEIN) (Immunogenic protein MPT32) (Antigen MPT-32) (45-kDa glycoprotein) (45/47 kDa antigen) Mb1891 1 COG5373 COG5373, Predicted membrane protein Function unknown 31792690 Pathogen - hypothetical protein Mb1531 1 None None None 31794407 Common - hypothetical protein Mb3255c 96 COG2135 COG2135, Uncharacterized conserved protein Function unknown 31791200 Common - POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN Mb0023 4 COG1396 HipB, Predicted transcriptional regulators Transcription 31794734 Common PPE64 PPE FAMILY PROTEIN Mb3588 5 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791866 Common rpsL 30S ribosomal protein S12 Mb0701 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 31792127 Common - ATP-dependent DNA ligase Mb0963 114 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 31792748 Common treYb Maltooligosyltrehalose synthase TreYb [SECOND PART] Mb1589c 58 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 31794448 Common - hypothetical protein Mb3296 13 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31792547 Pathogen - hypothetical protein Mb1386 1 None None None 31794430 Common rubB PROBABLE RUBREDOXIN RUBB Mb3278c 108 COG1773 COG1773, Rubredoxin Energy production and conversion 31792816 Common rpsA 30S ribosomal protein S1 Mb1656 224 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 31793122 Common - hypothetical protein Mb1965c 47 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 31793193 Common - POSSIBLE TRANSPOSASE Mb2036 11 None None None 31794301 Pathogen - hypothetical protein Mb3149c 1 None None None 31794693 Common cyp142b PROBABLE CYTOCHROME P450 MONOOXYGENASE 142 CYP142B [SECOND PART] Mb3547c 72 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 31791595 Common thiG thiazole synthase Mb0425 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 31794821 Common - hypothetical protein Mb3675 1 None None None 31793464 Common - conserved hypothetical protein [FIRST PART] Mb2308c 11 None None None 31794294 Common - PROBABLE TRANSPOSASE Mb3142 86 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 31794469 Common - POSSIBLE TRANSMEMBRANE PROTEIN Mb3317c 3 None None None 31791704 Common gabP PROBABLE GABA PERMEASE GABP (4-AMINO BUTYRATE TRANSPORT CARRIER) (GAMA-AMINOBUTYRATE PERMEASE) Mb0535 166 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 31791577 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0407 9 None None None 31794462 Common maf Maf-like protein Mb3310 158 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 31793422 Common - hypothetical protein Mb2266 29 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 31792503 Common atpD F0F1 ATP synthase subunit beta Mb1342 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 31792880 Common tlyA CYTOTOXIN Mb1720 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 31793854 Common dxs1 1-deoxy-D-xylulose-5-phosphate synthase Mb2701c 211 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 31794649 Common bpoA POSSIBLE PEROXIDASE BPOA (NON-HAEM PEROXIDASE) Mb3502c 104 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 31792671 Common - POSSIBLE MEMBRANE PROTEIN Mb1512 3 None None None 31792122 Common pstBb PHOSPHATE-TRANSPORT PROTEIN ABC TRANSPORTER PSTBb [SECOND PART] Mb0958 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 31793781 Common - PROBABLE MEMBRANE PROTEIN Mb2628 8 None None None 31792632 Common tpiA triosephosphate isomerase Mb1473 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 31794664 Common - hypothetical protein Mb3518 25 COG1695 COG1695, Predicted transcriptional regulators Transcription 31792516 Common - hypothetical protein Mb1355 38 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 31793924 Common - 3-ketoacyl-(acyl-carrier-protein) reductase Mb2771 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 31792181 Common - hypothetical protein Mb1017c 9 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 31792608 Common - hypothetical protein Mb1449 31 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 31794540 Common - hypothetical protein Mb3392 42 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 31791412 Common - PROBABLE CONSERVED TRANSMEMBRANE PROTEIN Mb0240c 9 None None None 31794382 Common - hypothetical protein Mb3230c 5 None None None 31795001 Common - PUTATIVE TRANSPOSASE Mb3857c 54 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 31794738 Common fadE31 PROBABLE ACYL-COA DEHYDROGENASE FADE31 Mb3592 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 31792983 Common - hypothetical protein Mb1823 2 None None None 31792118 Common pknDb TRANSMEMBRANE SERINE/THREONINE-PROTEIN KINASE D PKNDb [SECOND PART](PROTEIN KINASE D) (STPK D) Mb0954c 47 COG3391 COG3391, Uncharacterized conserved protein Function unknown 31793548 Pathogen PE_PGRS40 PE-PGRS FAMILY PROTEIN Mb2392 1 None None None 31794656 Common - CONSERVED HYPOTHETICAL PROTEIN [FIRST PART] Mb3510c 22 None None None 31793653 Pathogen - hypothetical protein Mb2499 1 None None None 31791687 Common serB1 POSSIBLE PHOSPHOSERINE PHOSPHATASE SERB1 (PSP) (O-PHOSPHOSERINE PHOSPHOHYDROLASE) (PSPASE) Mb0517c 97 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 31793530 Common - POSSIBLE CONSERVED TRANSMEMBRANE PROTEIN Mb2374 9 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 31793012 Common pgsA2 PROBABLE CDP-DIACYLGLYCEROL--GLYCEROL-3-PHOSPHATE 3-PHOSPHATIDYLTRANSFERASE PGSA2 (PGP SYNTHASE) (PHOSPHATIDYLGLYCEROPHOSPHATE SYNTHASE) (3-PHOSPHATIDYL-1'-GLYCEROL-3'PHOSPHATE SYNTHASE) Mb1853 198 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 31792792 Common hisI phosphoribosyl-AMP cyclohydrolase Mb1632 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 31792639 Common devB 6-phosphogluconolactonase Mb1480c 87 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 31792938 Common fadD1 acyl-CoA synthetase Mb1779c 219 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 31793989 Common - hypothetical protein Mb2837 59 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 31791631 Common PPE11 PPE FAMILY PROTEIN Mb0461 1 COG5651 COG5651, PPE-repeat proteins Cell motility and secretion 31791978 Pathogen - hypothetical protein Mb0813c 1 None None None 31792571 Common - PUTATIVE TRANSFERASE Mb1412c 130 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 31794929 Common proX POSSIBLE OSMOPROTECTANT (GLYCINE BETAINE/CARNITINE/CHOLINE/L-PROLINE) BINDING LIPOPROTEIN PROX Mb3785c 84 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 31794275 Common - hypothetical protein Mb3123 9 COG3934 COG3934, Endo-beta-mannanase Carbohydrate transport and metabolism 31794317 Common fadB4 PROBABLE NADPH QUINONE OXIDOREDUCTASE FADB4 (NADPH:QUINONE REDUCTASE) (ZETA-CRYSTALLIN) Mb3165 176 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 31794560 Common - hypothetical protein Mb3412c 2 None None None 31793629 Common valS valyl-tRNA synthetase Mb2475c 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 31793936 Common - CONSERVED HYPOTHETICAL PROTEIN [SECOND PART] Mb2783c 17 COG3214 COG3214, Uncharacterized protein conserved in bacteria Function unknown 31791921 Common sigL RNA polymerase sigma factor SigL Mb0756 115 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 31793899 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase Mb2746c 204 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 31794741 Common aspB aspartate aminotransferase Mb3595 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism