Pyrococcus horikoshii OT3, complete genome NC_000961 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 14590372 Nonpathogen - tRNA 2'-O-methylase PH0461 31 COG1303 COG1303, Uncharacterized protein conserved in archaea Function unknown 14590509 Nonpathogen - hypothetical protein PH0617 1 None None None 33359373 Nonpathogen - hypothetical protein PH1199.1n 1 None None None 14591239 Common - NADH dehydrogenase subunit B PH1449 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 14591466 Common - hypothetical protein PH1702 25 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 14590216 Nonpathogen - hypothetical protein PH0294 1 None None None 33359258 Nonpathogen - hypothetical protein PH0098 4 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 33359355 Nonpathogen - hypothetical protein PH1022.2n 2 None None None 14591295 Common - hypothetical protein PH1513 112 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 14590299 Nonpathogen - hypothetical protein PH0391 1 None None None 14590269 Common - glutamine synthetase PH0359 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 14591268 Nonpathogen tfb transcription initiation factor IIB PH1482 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 14591322 Common - hypothetical protein PH1540 41 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 14590252 Nonpathogen - hypothetical protein PH0337 2 None None None 14590608 Common - orotidine 5'-phosphate decarboxylase PH0731 98 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 14591152 Nonpathogen - hypothetical protein PH1345 9 COG0730 COG0730, Predicted permeases General function prediction only 14591534 Nonpathogen rpl4lp 50S ribosomal protein L4P PH1776 34 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 14591020 Nonpathogen - hypothetical protein PH1196 3 None None None 14591613 Nonpathogen - hypothetical protein PH1866 1 None None None 33359261 Common - hypothetical protein PH0166 9 COG1567 COG1567, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 14590280 Common - hypothetical protein PH0372 29 COG2266 COG2266, GTP:adenosylcobinamide-phosphate guanylyltransferase Coenzyme metabolism 14591163 Common - putative thiazole biosynthetic enzyme PH1357 32 COG1635 THI4, Flavoprotein involved in thiazole biosynthesis Coenzyme metabolism 14590097 Common - hypothetical protein PH0159 111 COG1268 BioY, Uncharacterized conserved protein General function prediction only 14590027 Nonpathogen - hypothetical protein PH0073 18 COG1432 COG1432, Uncharacterized conserved protein Function unknown 14591192 Common - 2-dehydropantoate 2-reductase PH1390 132 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 14590418 Nonpathogen - hypothetical protein PH0516 1 None None None 14590750 Common - hypothetical protein PH0893 150 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 14591193 Common - hypothetical protein PH1391 107 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 14591027 Common - ferrous iron transport protein B PH1205 236 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 14590350 Common - hypothetical protein PH0435 242 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 14590628 Nonpathogen - hypothetical protein PH0758 1 None None None 14591702 Common - dihydroorotase PH1963 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 14590910 Common - homoserine dehydrogenase PH1075 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 14590206 Common - hypothetical protein PH0282 46 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 14590706 Nonpathogen - hypothetical protein PH0845 1 None None None 14591299 Common - hypothetical protein PH1517 163 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 14591620 Common - putative oxidoreductase PH1873 238 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 14590355 Common - translation initiation factor IF-2B subunit alpha PH0440 132 COG1184 GCD2, Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 14590270 Common - hypothetical protein PH0360 7 None None None 14590675 Common - oligopeptide transport permease protein APPB PH0808 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 14590913 Common - fmu protein PH1078 209 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 14591594 Nonpathogen - hypothetical protein PH1846 24 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 14591509 Nonpathogen - hypothetical protein PH1752 9 COG1422 COG1422, Predicted membrane protein Function unknown 14590009 Common - hypothetical protein PH0056 216 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 14591684 Common eno phosphopyruvate hydratase PH1942 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 14591337 Nonpathogen - hypothetical protein PH1554 21 COG2150 COG2150, Predicted regulator of amino acid metabolism, contains ACT domain General function prediction only 14591735 Nonpathogen secE preprotein translocase subunit SecE PH0002a 2 COG2443 Sss1, Preprotein translocase subunit Sss1 Intracellular trafficking and secretion 14591174 Common - aspartate aminotransferase PH1371 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 14591182 Nonpathogen - ribosome biogenesis protein PH1379 18 COG1756 Mra1, Uncharacterized conserved protein Function unknown 14591290 Common - hypothetical protein PH1507 249 COG2401 COG2401, ABC-type ATPase fused to a predicted acetyltransferase domain General function prediction only 14590069 Common - 5'-methylthioadenosine phosphorylase II PH0125 167 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 14590492 Common - pyrrolidone-carboxylate peptidase PH0596 58 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 14590379 Nonpathogen - hypothetical protein PH0467 1 None None None 14590034 Common - hypothetical protein PH0081 66 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 14590228 Nonpathogen - hypothetical protein PH0309 3 COG3780 COG3780, DNA endonuclease related to intein-encoded endonucleases DNA replication, recombination, and repair 14591358 Common - ATP-binding protein PH1580 228 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 18656945 Common hypC Hydrogenase maturation factor PH0878a 102 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 14591371 Common - glutamate dehydrogenase PH1593 179 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 14591565 Nonpathogen - hypothetical protein PH1812 33 COG1571 COG1571, Predicted DNA-binding protein containing a Zn-ribbon domain General function prediction only 14590051 Nonpathogen - tRNA CCA-pyrophosphorylase PH0101 34 COG1746 CCA1, tRNA nucleotidyltransferase (CCA-adding enzyme) Translation, ribosomal structure and biogenesis 33359305 Nonpathogen - hypothetical protein PH0580.1n 1 None None None 14591347 Nonpathogen - hypothetical protein PH1566 33 COG1094 COG1094, Predicted RNA-binding protein (contains KH domains) General function prediction only 14591330 Nonpathogen rpoH DNA-directed RNA polymerase subunit H PHS044 28 COG2012 RPB5, DNA-directed RNA polymerase, subunit H, RpoH/RPB5 Transcription 14591368 Common - hypothetical protein PH1590 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 14590635 Common - hypothetical protein PH0766 205 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 14590450 Nonpathogen - flagellin PH0550 7 COG1681 FlaB, Archaeal flagellins Cell motility and secretion 14591693 Common - phosphoribosylformylglycinamidine synthase II PH1953 235 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 14590718 Common - aspartate kinase PH0858 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 14590045 Nonpathogen - hypothetical protein PH0094 29 COG1031 COG1031, Uncharacterized Fe-S oxidoreductase Energy production and conversion 14590425 Common - molybdenum cofactor biosynthesis protein PH0523 141 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 14591149 Nonpathogen - hypothetical protein PH1342 2 None None None 14590090 Common - hypothetical protein PH0151 27 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 14591685 Nonpathogen - hypothetical protein PH1943 8 COG1365 COG1365, Predicted ATPase (PP-loop superfamily) General function prediction only 14590246 Common - hypothetical protein PH0331 76 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 14590019 Common - hypothetical protein PH0065 42 COG2339 COG2339, Predicted membrane protein Function unknown 14591586 Nonpathogen - hypothetical protein PH1837 1 None None None 14591399 Common - mevalonate kinase PH1625 53 COG1577 ERG12, Mevalonate kinase Lipid metabolism 14590993 Nonpathogen - hypothetical protein PH1167 1 None None None 14590062 Nonpathogen - hypothetical protein PH0116 2 None None None 14590775 Nonpathogen - hypothetical protein PH0921 2 None None None 14591543 Nonpathogen - hypothetical protein PH1785 7 COG3371 COG3371, Predicted membrane protein Function unknown 14591112 Nonpathogen - hypothetical protein PH1302 2 None None None 14590727 Nonpathogen - hypothetical protein PH0868 1 None None None 14591300 Nonpathogen rpl37e 50S ribosomal protein L37e PHS041 29 COG2126 RPL37A, Ribosomal protein L37E Translation, ribosomal structure and biogenesis 14591159 Common - formate dehydrogenase PH1353 200 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 14591659 Common - hypothetical protein PH1917 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 14591402 Common rps2P 30S ribosomal protein S2 PH1629 159 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 33359439 Nonpathogen - preprotein translocase subunit SecG PH1895.1n 2 COG4023 SBH1, Preprotein translocase subunit Sec61beta Intracellular trafficking and secretion 14590346 Common - hypothetical protein PH0430 224 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 14591104 Common - cytochrome-c3 hydrogenase alpha chain PH1294 78 COG3259 FrhA, Coenzyme F420-reducing hydrogenase, alpha subunit Energy production and conversion 14591427 Common - hypothetical protein PH1658 23 COG2426 COG2426, Predicted membrane protein Function unknown 14590290 Nonpathogen - hypothetical protein PH0381 17 COG4743 COG4743, Predicted membrane protein Function unknown 14591502 Common - hypothetical protein PH1744 35 COG1777 COG1777, Predicted transcriptional regulators Transcription 14591081 Nonpathogen - hypothetical protein PH1264 1 None None None 14590553 Common - hypothetical protein PH0671 130 COG2096 COG2096, Uncharacterized conserved protein Function unknown 14590658 Common - iron (III) dicitrate transport system permease protein PH0790 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 14591667 Common - ribose-phosphate pyrophosphokinase PH1923 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 14590988 Common - transcriptional regulator PH1161 74 COG0819 TenA, Putative transcription activator Transcription 14590292 Nonpathogen - hypothetical protein PH0383 6 None None None 14590903 Common ileS isoleucyl-tRNA synthetase PH1065 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 33359410 Nonpathogen - hypothetical protein PH1498.1n 2 None None None 14590058 Common - replication factor C small subunit PH0112 82 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 14590015 Common - hypothetical protein PHS001 30 COG1694 MazG, Predicted pyrophosphatase General function prediction only 14591257 Common - hypothetical protein PH1469 86 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 14590166 Common - hypothetical protein PH0235 31 COG3273 COG3273, Uncharacterized conserved protein Function unknown 14590681 Common - hypothetical protein PH0814 44 COG1865 COG1865, Uncharacterized conserved protein Function unknown 14590533 Common - 2-hydroxyhepta-2,4-diene-1,7-dioate isomerase PH0643 181 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 14590728 Nonpathogen - hypothetical protein PH0869 1 None None None 14591119 Common - serine aminotransferase PH1308 188 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 14591601 Common - hypothetical protein PH1855 62 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 14591283 Common - hypothetical protein PH1497 79 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 14590152 Nonpathogen - hypothetical protein PHS004 2 None None None 14591436 Common - signal recognition particle protein PH1669 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 14591729 Common - glycine dehydrogenase subunit 1 PH1995 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 14590616 Common - alchol dehydrogenase PH0743 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 14590110 Common - hypothetical protein PH0173 92 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 33359423 Nonpathogen - hypothetical protein PH1721.1n 2 None None None 14591216 Common - phosphoglycolate phosphatase PH1421 96 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 14589984 Common - sugar transport membrane protein PH0023 190 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 14591486 Common aksA trans-homoaconitate synthase PH1727 215 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 14590234 Nonpathogen - hypothetical protein PHS006 1 None None None 33359328 Common - hypothetical protein PH0771.1n 22 COG2119 COG2119, Predicted membrane protein Function unknown 14589981 Common - hypothetical protein PH0020 43 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 33359296 Nonpathogen - hypothetical protein PH0466.2n 1 COG2810 COG2810, Predicted type IV restriction endonuclease Defense mechanisms 14590092 Nonpathogen - hypothetical protein PH0153 3 None None None 14590891 Common - hydantoin racemase PH1054 24 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 14591442 Common - hypothetical protein PH1678 9 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 14590847 Common - prolyl-tRNA synthetase PH1006 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 33359429 Nonpathogen - hypothetical protein PH1818.1n 1 None None None 14591522 Nonpathogen - 30S ribosomal protein S4e PH1766 34 COG1471 RPS4A, Ribosomal protein S4E Translation, ribosomal structure and biogenesis 14591714 Common - V-type ATP synthase subunit C PH1977 29 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 14590020 Common - L-asparaginase PH0066 151 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 14590119 Common - molybdopterinconverting factor, subunit PH0184 161 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 33359394 Nonpathogen - hypothetical protein PH1344.1n 2 None None None 14590539 Common - secretory protein kinase PH0650 202 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 14591632 Nonpathogen - hypothetical protein PH1887 15 COG1590 COG1590, Uncharacterized conserved protein Function unknown 14590100 Common - hypothetical protein PH0162 30 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 33359303 Nonpathogen - hypothetical protein PH0564 3 None None None 14590953 Common - geranylgeranylglyceryl phosphate synthase-like protein PH1124 27 COG1646 COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold General function prediction only 14590503 Nonpathogen - hypothetical protein PH0610 2 COG1711 COG1711, Uncharacterized protein conserved in archaea Function unknown 14591643 Nonpathogen - ribosomal biogenesis protein PH1900 4 COG2136 IMP4, Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 domain Translation, ribosomal structure and biogenesis / RNA processing and modification 14591307 Nonpathogen nac nascent polypeptide-associated complex protein PH1524 32 COG1308 EGD2, Transcription factor homologous to NACalpha-BTF3 Transcription 14591001 Nonpathogen - hypothetical protein PH1175 1 None None None 14591493 Common - ABC transporter ATP-binding protein PH1735 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 14590514 Nonpathogen - hypothetical protein PH0623 2 None None None 14590826 Common - hypothetical protein PH0981 45 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 14591390 Common - hypothetical protein PH1615 144 COG2100 COG2100, Predicted Fe-S oxidoreductase General function prediction only 14590852 Common - hypothetical protein PH1012 32 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 14590137 Common - maltose transport system permease protein PH0204 162 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 14591073 Nonpathogen - putative kinase PH1255 31 COG1936 COG1936, Predicted nucleotide kinase (related to CMP and AMP kinases) Nucleotide transport and metabolism 14590396 Common - histidine kinase (cheA) PH0484 170 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 33359432 Nonpathogen - hypothetical protein PH1842.1n 2 COG0392 COG0392, Predicted integral membrane protein Function unknown 14590108 Nonpathogen - hypothetical protein PH0171 2 COG1688 COG1688, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 14590857 Common - cofactor modifying protein PH1017 98 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 14590835 Nonpathogen - hypothetical protein PH0990 33 COG1499 NMD3, NMD protein affecting ribosome stability and mRNA decay Translation, ribosomal structure and biogenesis 14591204 Common pyrH uridylate kinase PH1408 132 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 14591619 Nonpathogen - hypothetical protein PH1872 1 None None None 14590307 Common - hypothetical protein PH0399 182 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 14590128 Common - alpha-amylase PH0193 23 COG1449 COG1449, Alpha-amylase/alpha-mannosidase Carbohydrate transport and metabolism 14591447 Common - fumarate hydratase PH1683 147 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 14591498 Nonpathogen - hypothetical protein PH1740 9 COG5316 COG5316, Uncharacterized conserved protein Function unknown 14590782 Common - chromosome segregation protein PH0929 176 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 14591092 Common - hypothetical protein PH1278 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 14590146 Nonpathogen - hypothetical protein PH0213 5 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 14590174 Common - D-fructose-6-phosphate amidotransferase PH0243 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 14590117 Common nadE NAD synthetase PH0182 217 COG0171 NadE, NAD synthase Coenzyme metabolism 14590485 Nonpathogen - ADP-specific phosphofructokinase PH0589 8 COG4809 COG4809, Archaeal ADP-dependent phosphofructokinase/glucokinase Carbohydrate transport and metabolism 14591315 Nonpathogen - hypothetical protein PH1533 2 None None None 14590336 Nonpathogen - hypothetical protein PH0419 2 COG2253 COG2253, Uncharacterized conserved protein Function unknown 14590076 Common - transport protein PH0132 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 14590842 Common - hypothetical protein PH1000 59 COG0628 PerM, Predicted permease General function prediction only 14590388 Nonpathogen - hypothetical protein PH0476 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 14591123 Nonpathogen - hypothetical protein PHS038 12 COG1849 COG1849, Uncharacterized protein conserved in archaea Function unknown 14591760 Nonpathogen rps27e 30S ribosomal protein S27e PH1939a 34 COG2051 RPS27A, Ribosomal protein S27E Translation, ribosomal structure and biogenesis 14591395 Nonpathogen - hypothetical protein PH1620 21 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 14591597 Nonpathogen - hypothetical protein PH1850 2 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 14591340 Common - hypothetical protein PH1557 168 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 14591135 Common - hypothetical protein PH1323 24 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 14591481 Common argC N-acetyl-gamma-glutamyl-phosphate reductase PH1720 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 14590495 Nonpathogen - hypothetical protein PH0599 1 None None None 14590816 Nonpathogen - hypothetical protein PH0971 1 None None None 14591417 Common - molybdopterin biosynthesis moeA protein PH1647 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 14590561 Common vorD 2-ketoisovalerate ferredoxin oxidoreductase subunit delta PH0679 90 COG1144 COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit Energy production and conversion 14590945 Nonpathogen - hypothetical protein PH1115 8 COG2383 COG2383, Uncharacterized conserved protein Function unknown 14590643 Common - hypothetical protein PH0774 100 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 14590595 Common - hypothetical protein PH0718 105 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 14590656 Nonpathogen - hypothetical protein PH0787 2 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 14591133 Nonpathogen - hypothetical protein PH1321 6 COG1800 COG1800, Predicted transglutaminase-like proteases General function prediction only 14590197 Common - hypothetical protein PH0272 100 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 14590731 Common - hypothetical protein PH0872 16 COG1700 COG1700, Uncharacterized conserved protein Function unknown 14591574 Common ksgA dimethyladenosine transferase PH1823 249 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 14591273 Nonpathogen - hypothetical protein PH1488 12 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 14591261 Nonpathogen - hypothetical protein PH1473 2 None None None 33359360 Nonpathogen - hypothetical protein PH1079.1n 2 None None None 14591758 Nonpathogen rps24e 30S ribosomal protein S24e PH1909a 18 COG2004 RPS24A, Ribosomal protein S24E Translation, ribosomal structure and biogenesis 14590950 Common - hypothetical protein PH1120 17 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 14590006 Nonpathogen - hypothetical protein PH0053 34 COG1498 SIK1, Protein implicated in ribosomal biogenesis, Nop56p homolog Translation, ribosomal structure and biogenesis 14590451 Nonpathogen - flagellin PH0551 6 COG1681 FlaB, Archaeal flagellins Cell motility and secretion 14591025 Common - isopentenyl pyrophosphate isomerase PH1202 88 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 14590972 Nonpathogen - hypothetical protein PH1144 2 None None None 14590406 Nonpathogen - hypothetical protein PH0500 3 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 14591318 Common - hypothetical protein PH1536 44 COG1371 COG1371, Uncharacterized conserved protein Function unknown 14591414 Common - H/ACA RNA-protein complex component Cbf5p PH1644 244 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 14591514 Common rps5p 30S ribosomal protein S5P PH1757 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 14591650 Common - hypothetical protein PH1905 38 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 14590460 Nonpathogen - hypothetical protein PH0561 3 COG4365 COG4365, Uncharacterized protein conserved in bacteria Function unknown 14591634 Common - hypothetical protein PH1889 46 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 14589975 Common - quinolinate synthetase PH0013 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 14590759 Common - hypothetical protein PH0905 40 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 14591058 Nonpathogen - hypothetical protein PH1239 8 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 14590543 Common pheT phenylalanyl-tRNA synthetase subunit beta PH0657 241 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 33359380 Nonpathogen - hypothetical protein PHS033.1n 4 None None None 14591063 Nonpathogen - hypothetical protein PH1244 29 COG1634 COG1634, Uncharacterized Rossmann fold enzyme General function prediction only 14590792 Nonpathogen - hypothetical protein PH0940 4 None None None 14590711 Nonpathogen - hypothetical protein PH0850 1 None None None 14590979 Common - ribonuclease Z PH1151 135 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 14591424 Common - hypothetical protein PH1655 164 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 14590801 Common - MRP protein PH0949 239 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 14590588 Common - seryl-tRNA synthetase PH0710 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 14591165 Common - hypothetical protein PH1359 180 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 14590878 Nonpathogen - hypothetical protein PH1040 1 None None None 161350001 Common rps17p 30S ribosomal protein S17P PH1770 95 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 14590482 Nonpathogen - hypothetical protein PH0586 1 None None None 33359369 Nonpathogen - hypothetical protein PH1174.1n 1 None None None 14591730 Nonpathogen - hypothetical protein PH1996 4 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 14590047 Common - hypothetical protein PH0096 122 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 14590898 Common - hypothetical protein PH1061 17 COG1846 MarR, Transcriptional regulators Transcription 14591093 Common - ski2-like helicase PH1280 142 COG1204 COG1204, Superfamily II helicase General function prediction only 14590327 Nonpathogen - hypothetical protein PHS017 1 None None None 14589968 Nonpathogen - hypothetical protein PH0006 28 COG1650 COG1650, Uncharacterized protein conserved in archaea Function unknown 14590160 Common - indolepyruvate oxidoreductase subunit B PH0229 92 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 14590169 Nonpathogen - hypothetical protein PH0238 2 None None None 14591712 Common - V-type ATP synthase subunit A PH1975 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 14591455 Common - hypothetical protein PH1693 22 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 33359443 Nonpathogen - hypothetical protein PH1935.1n 2 None None None 33359345 Nonpathogen - hypothetical protein PHS029 10 COG2034 COG2034, Predicted membrane protein Function unknown 14590814 Nonpathogen - hypothetical protein PH0969 1 None None None 14590576 Common - hypothetical protein PH0697 84 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 14591437 Common - metal-dependent hydrolase PH1671 130 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 14591468 Common - intracellular proteinase PH1704 165 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 33359285 Nonpathogen - hypothetical protein PHS010.3n 1 None None None 14591176 Nonpathogen - hypothetical protein PH1373 2 None None None 14590432 Nonpathogen - hypothetical protein PH0531 2 None None None 14590032 Common - D-aminopeptidase PH0078 57 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 14591270 Common - elongation factor 1-alpha PH1484 249 COG5256 TEF1, Translation elongation factor EF-1alpha (GTPase) Translation, ribosomal structure and biogenesis 14591117 Nonpathogen rpl40e 50S ribosomal protein L40e PHS037 27 COG1552 RPL40A, Ribosomal protein L40E Translation, ribosomal structure and biogenesis 14590618 Common - hypothetical protein PH0745 32 COG1415 COG1415, Uncharacterized conserved protein Function unknown 14590563 Common - 2-ketoisovalerate ferredoxin oxidoreductase subunit beta PH0681 100 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 14591470 Common - translation initiation factor IF-2 subunit gamma PH1706 249 COG5257 GCD11, Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase) Translation, ribosomal structure and biogenesis 14591189 Common - hypothetical protein PH1386 35 COG1543 COG1543, Uncharacterized conserved protein Function unknown 14590465 Nonpathogen - hypothetical protein PH0566 3 None None None 33359333 Nonpathogen - hypothetical protein PH0815.1n 1 None None None 18656947 Common purS phosphoribosylformylglycinamidine synthase subunit PurS PH1955a 74 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 14590086 Common - magnesium and cobalt transport protein PH0144 180 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 14591691 Common - hypothetical protein PH1950 218 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 14590180 Nonpathogen - hypothetical protein PH0251 2 COG3601 COG3601, Predicted membrane protein Function unknown 14591233 Common - ATP-dependent proteinase La PH1442 208 COG1750 COG1750, Archaeal serine proteases General function prediction only 14590611 Nonpathogen - hypothetical protein PH0736 3 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 14591439 Nonpathogen - hypothetical protein PH1673 3 COG2247 LytB, Putative cell wall-binding domain Cell envelope biogenesis, outer membrane 14590541 Common - hypothetical protein PH0654 50 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 14590494 Nonpathogen - hypothetical protein PH0598 3 None None None 14590423 Nonpathogen - hypothetical protein PH0521 1 None None None 14591332 Common - exosome complex RNA-binding protein Rrp42 PH1548 65 COG2123 COG2123, RNase PH-related exoribonuclease Translation, ribosomal structure and biogenesis 14590221 Nonpathogen - hypothetical protein PH0298 2 None None None 14591110 Nonpathogen - hypothetical protein PH1300 1 None None None 14591687 Nonpathogen - hypothetical protein PH1946 1 None None None 14590126 Common - L-fuculose phosphate aldolase PH0191 158 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 33359247 Nonpathogen - hypothetical protein PH0005.1n 2 None None None 161350008 Common - homoserine kinase PH1087 121 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 14590766 Common - hypothetical protein PH0911 190 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 14590043 Common - phosphoenolpyruvate synthase PH0092 236 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 14590673 Nonpathogen - hypothetical protein PH0806 1 COG5608 COG5608, Conserved secreted protein Function unknown 33359407 Nonpathogen - hypothetical protein PH1458.1n 2 None None None 14590250 Nonpathogen - hypothetical protein PH0335 10 COG2430 COG2430, Uncharacterized conserved protein Function unknown 14590422 Common - 2-hydroxyacid dehydrogenase PH0520 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 14591556 Common - hypothetical protein PH1803 10 None None None 14590260 Common - UDP-N-acetylglucosamine-dolichyl-phosphate N-AceGluNH-phosphotransferase PH0348 49 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 14591199 Nonpathogen - hypothetical protein PH1400 2 None None None 14591584 Common - methylated-DNA--protein-cysteine methyltransferase PH1835 120 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 14590313 Nonpathogen - hypothetical protein PH0406 3 None None None 14590748 Common - aldehyde:ferredoxin oxidoreductase PH0891 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 14590218 Common - acetyltransferase PH0296 197 COG0456 RimI, Acetyltransferases General function prediction only 14590254 Common - hypothetical protein PH0340 23 COG1107 COG1107, Archaea-specific RecJ-like exonuclease, contains DnaJ-type Zn finger domain DNA replication, recombination, and repair 33359378 Nonpathogen - hypothetical protein PH1227.1n 1 None None None 14591037 Common - peroxiredoxin PH1217 214 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 14591560 Common - DNA damage-inducible protein PH1807 184 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 33359256 Nonpathogen - hypothetical protein PH0097.1n 2 None None None 14590633 Common - indolepyruvate oxidoreductase subunit B PH0764 108 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 14591451 Common - hypothetical protein PH1688 39 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 14590704 Common - hypothetical protein PH0843 19 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14590695 Common - hypothetical protein PH0828 16 COG2105 COG2105, Uncharacterized conserved protein Function unknown 14590602 Nonpathogen - diphthine synthase PH0725 34 COG1798 DPH5, Diphthamide biosynthesis methyltransferase Translation, ribosomal structure and biogenesis 14590752 Common - cation efflux system protein czcD PH0896 217 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 14590374 Common - hypothetical protein PH0463 74 COG1912 COG1912, Uncharacterized conserved protein Function unknown 14591477 Common - hypothetical protein PH1714 88 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 14590208 Common - hypothetical protein PH0284 96 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 14591281 Nonpathogen rps28e 30S ribosomal protein S28e PHS040 33 COG2053 RPS28A, Ribosomal protein S28E/S33 Translation, ribosomal structure and biogenesis 14591356 Nonpathogen - hypothetical protein PH1578 11 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 14590439 Nonpathogen - hypothetical protein PH0538 2 COG2245 COG2245, Predicted membrane protein Function unknown 14590357 Common - hypothetical protein PH0442 65 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 14590094 Common - hypothetical protein PH0155 18 COG1106 COG1106, Predicted ATPases General function prediction only 14591311 Common - RNA 3'-terminal-phosphate cyclase PH1529 47 COG0430 RCL1, RNA 3'-terminal phosphate cyclase RNA processing and modification 14591727 Nonpathogen - hypothetical protein PH1993 5 COG3233 COG3233, Predicted deacetylase General function prediction only 14591507 Common - ferredoxin PH1750 24 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 14590924 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase PH1090 44 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 14590653 Common - hypothetical protein PHS025 17 COG1694 MazG, Predicted pyrophosphatase General function prediction only 14590236 Common purT phosphoribosylglycinamide formyltransferase 2 PH0318 209 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 14590854 Common - aromatic acid decarboxylase PH1014 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 33359298 Nonpathogen - hypothetical protein PH0500.1n 3 None None None 33359440 Common - ERCC4-like helicase/ERCC4-type nuclease PH1896m.1n 199 COG1111 MPH1, ERCC4-like helicases DNA replication, recombination, and repair 14590226 Nonpathogen - hypothetical protein PH0306 20 COG2150 COG2150, Predicted regulator of amino acid metabolism, contains ACT domain General function prediction only 14591343 Nonpathogen - hypothetical protein PH1560 7 COG1710 COG1710, Uncharacterized protein conserved in archaea Function unknown 14590578 Common - threonyl-tRNA synthetase PH0699 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 14591567 Common - cobalt transport ATP-binding protein PH1815 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 14590520 Nonpathogen - hypothetical protein PH0629 36 COG1833 COG1833, Uncharacterized conserved protein Function unknown 33359386 Nonpathogen - hypothetical protein PH1295.1n 1 None None None 14590583 Nonpathogen - hypothetical protein PH0705 1 None None None 14589999 Common - hypothetical protein PH0044 213 COG1202 COG1202, Superfamily II helicase, archaea-specific General function prediction only 33359420 Nonpathogen - hypothetical protein PH1682.1n 1 None None None 14590845 Common - helicase PH1003 170 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 161350011 Common - pyruvate kinase PH0570 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 14590740 Common - hypothetical protein PH0883 100 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 14591627 Common - hypothetical protein PH1881 191 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 14590102 Common - hypothetical protein PH0165 33 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 14591078 Common - hypothetical protein PH1260 209 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 33359396 Nonpathogen - hypothetical protein PH1358 2 None None None 14590679 Common - hypothetical protein PH0812 72 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 14591190 Common - phosphoglycerate dehydrogenase PH1387 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 14591241 Common - NADH dehydrogenase subunit M PH1451 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 14590444 Nonpathogen - hypothetical protein PH0543 2 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 14591520 Nonpathogen rps14P 30S ribosomal protein S14P PHS047 30 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 14590669 Common - hypothetical protein PH0802 40 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 14590908 Common - geranylgeranyl pyrophosphate synthetase PH1072 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 33359427 Common rpmC 50S ribosomal protein L29 PHS048 24 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 14590529 Common - hypothetical protein PH0637 43 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 14591030 Common - hypothetical protein PH1209 42 COG0434 SgcQ, Predicted TIM-barrel enzyme General function prediction only 33359366 Nonpathogen - hypothetical protein PH1152.1n 1 None None None 14591750 Nonpathogen - 50S ribosomal protein L24e PH1495a 32 COG2075 RPL24A, Ribosomal protein L24E Translation, ribosomal structure and biogenesis 14590368 Common - hypothetical protein PH0457 36 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 14590790 Common - hypothetical protein PH0938 14 COG1856 COG1856, Uncharacterized homolog of biotin synthetase Function unknown 14591018 Nonpathogen - hypothetical protein PH1193 2 None None None 14590551 Common - hypothetical protein PH0667 199 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 14590386 Common - Na(+)/Ca(2+)-exchanging protein PH0473 123 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 14591536 Nonpathogen - hypothetical protein PH1779 22 COG2106 COG2106, Uncharacterized conserved protein Function unknown 14590943 Common - hypothetical protein PH1113 56 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 14590976 Nonpathogen - hypothetical protein PH1148 2 None None None 14591023 Nonpathogen - hypothetical protein PH1200 5 COG4342 COG4342, Uncharacterized protein conserved in archaea Function unknown 14591725 Common - nucleolar protein PH1991 211 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 33359321 Nonpathogen - hypothetical protein PH0707.2n 3 None None None 14591353 Common - hydrogenase expression/formation protein PH1573 140 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 14590303 Nonpathogen - hypothetical protein PH0395 1 None None None 14590088 Common - biotin--protein ligase PH0147 231 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 14591583 Common - thiamine monophosphate kinase PH1833 206 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 14590883 Common - hypothetical protein PH1046 28 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 14591545 Nonpathogen - hypothetical protein PH1787 2 None None None 14590738 Common - hypothetical protein PH0881 19 COG4273 COG4273, Uncharacterized conserved protein Function unknown 14589992 Common - hypothetical protein PH0034 40 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 14590721 Nonpathogen - hypothetical protein PH0861 3 None None None 14590933 Common - asparagine synthetase PH1102 218 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 14590981 Common - acetylornithine deacetylase PH1153 178 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 14591048 Nonpathogen - N-glycosylase/DNA lyase PH1229 12 COG4047 COG4047, Uncharacterized protein conserved in archaea Function unknown 14591171 Common - ATP-binding transport protein PH1366 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 14591083 Common - cytidylate kinase PH1265 57 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 14590901 Nonpathogen - hypothetical protein PH1063 1 None None None 14590332 Common - dTDP-glucose 4,6-dehydratase PH0414 234 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 14591142 Nonpathogen - hypothetical protein PH1334 2 None None None 14591647 Common - hypothetical protein PH1902 141 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 14590365 Nonpathogen - hypothetical protein PH0451 15 COG1310 COG1310, Predicted metal-dependent protease of the PAD1/JAB1 superfamily General function prediction only 14590968 Nonpathogen - hypothetical protein PH1140 2 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 33359307 Nonpathogen - hypothetical protein PH0584.1n 5 None None None 14591377 Common - cell division inhibitor PH1600 166 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 14591500 Common - UDP-glucose 4-epimerase PH1742 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 14591138 Nonpathogen - hypothetical protein PH1327 3 None None None 14591218 Common - 4-aminobutyrate aminotransferase PH1423 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 14590170 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase PH0239 220 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 14590837 Common metG methionyl-tRNA synthetase PH0993 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 14590799 Common - NAD-dependent deacetylase PH0947 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 14591245 Common - putative monovalent cation/H+ antiporter subunit G PH1455 76 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 14590780 Nonpathogen - hypothetical protein PH0927 5 None None None 14591388 Common - hypothetical protein PH1613 6 COG2306 COG2306, Uncharacterized conserved protein Function unknown 14590638 Nonpathogen - hypothetical protein PHS024 6 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 14591405 Common rps9p 30S ribosomal protein S9P PH1633 110 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 14590840 Nonpathogen - hypothetical protein PH0997 26 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 14591461 Nonpathogen - hypothetical protein PH1698 1 None None None 33359430 Nonpathogen - hypothetical protein PH1824.1n 5 COG4026 COG4026, Uncharacterized protein containing TOPRIM domain, potential nuclease General function prediction only 14591313 Common - hypothetical protein PH1531 11 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 14591419 Nonpathogen - hypothetical protein PH1649 1 None None None 14591665 Nonpathogen - hypothetical protein PHS059 28 COG1698 COG1698, Uncharacterized protein conserved in archaea Function unknown 14591440 Nonpathogen - hypothetical protein PH1674 4 COG2247 LytB, Putative cell wall-binding domain Cell envelope biogenesis, outer membrane 14591095 Common - carbamate kinase-like carbamoyl phosphate synthetase PH1282 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 14590199 Common - methylmalony-CoA mutase PH0275 107 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 14590712 Common - fmu protein PH0851 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 14590144 Common speE spermidine synthase PH0211 112 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 14590645 Nonpathogen - hypothetical protein PH0777 1 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 14590334 Common - dTDP-4-dehydrorhamnose 3,5-epimerase PH0416 168 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 14590064 Common radB DNA repair and recombination protein RadB PH0119 149 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 14590597 Common pyrB aspartate carbamoyltransferase catalytic subunit PH0720 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 14590885 Common - hypothetical protein PH1048 46 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 14591397 Common - ATP-dependent DNA ligase PH1622 112 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 14590262 Common - hypothetical protein PH0351 42 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 14591131 Nonpathogen - hypothetical protein PH1319 5 COG2245 COG2245, Predicted membrane protein Function unknown 14591035 Common - sugar-binding transport system permease protein PH1215 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 14590497 Common - nickel responsive regulator PH0601 68 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 14591599 Nonpathogen - hypothetical protein PH1853 2 None None None 14590305 Common - hypothetical protein PH0397 31 COG1887 TagB, Putative glycosyl/glycerophosphate transferases involved in teichoic acid biosynthesis TagF/TagB/EpsJ/RodC Cell envelope biogenesis, outer membrane 14591641 Nonpathogen - hypothetical protein PH1898 17 COG1967 COG1967, Predicted membrane protein Function unknown 14591572 Common - operon protein Frv PH1821 88 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 14590272 Common - ribonucleotide-diphosphate reductase alpha subunit PH0363 234 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 14590201 Nonpathogen - hypothetical protein PH0277 2 None None None 14591309 Common - Frv operon protein FrvX PH1527 91 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 14590151 Nonpathogen - hypothetical protein PHS003 1 None None None 14591710 Nonpathogen - hypothetical protein PH1973 1 None None None 14591049 Common - ATP-binding transport protein PH1230 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 14591657 Common - hypothetical protein PH1915 125 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 14591495 Nonpathogen - hypothetical protein PH1737 5 None None None 14590411 Common - oligopeptide transport ATP-binding protein AppF PH0505 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 14591453 Common - adenine phosphoribosyltransferase PH1691 93 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 14590585 Nonpathogen - hypothetical protein PH0707 2 None None None 14591664 Nonpathogen - hypothetical protein PHS058 1 None None None 14590402 Nonpathogen - hypothetical protein PH0494 14 COG2469 COG2469, Uncharacterized conserved protein Function unknown 14591292 Common - nfeD protein PH1510 80 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 14590134 Common - GTP-binding protein PH0200 173 COG0218 COG0218, Predicted GTPase General function prediction only 14591612 Nonpathogen - hypothetical protein PH1865 2 None None None 14590231 Common - phosphoenolpyruvate carboxykinase PH0312 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 14591227 Common - NADH-ubiquinone oxidoreductase subunit PH1434 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 14590186 Common - hypothetical protein PH0259 48 COG1836 COG1836, Predicted membrane protein Function unknown 14591075 Nonpathogen - zinc finger protein PHS034 4 COG4049 COG4049, Uncharacterized protein containing archaeal-type C2H2 Zn-finger General function prediction only 14591255 Nonpathogen - hypothetical protein PH1467 2 None None None 14590824 Common - hydrogenase PH0979 38 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 14590158 Common - hypothetical protein PH0227 32 COG1907 COG1907, Predicted archaeal sugar kinases General function prediction only 14590626 Common - sugar transport ATP-binding protein PH0756 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 14591617 Nonpathogen - hypothetical protein PH1870 1 None None None 14591265 Common argS arginyl-tRNA synthetase PH1478 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 14590651 Nonpathogen - transcription factor PH0783 33 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 14590830 Common - arylmalonate decarboxylase PH0985 48 COG3473 COG3473, Maleate cis-trans isomerase Secondary metabolites biosynthesis, transport, and catabolism 14591445 Nonpathogen - hypothetical protein PH1681 3 None None None 14590859 Common - aldehyde:ferredoxin oxidoreductase PH1019 58 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 14591636 Nonpathogen - hypothetical protein PH1892 1 None None None 14590760 Nonpathogen - hypothetical protein PH0907 4 COG2028 COG2028, Uncharacterized conserved protein Function unknown 14590516 Common - hypothetical protein PH0625 145 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 14591733 Nonpathogen rplP0 acidic ribosomal protein P0 PH1999 34 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 14590687 Common - ATP-binding protein PH0820 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 14591698 Common - oligopeptide transport ATP-binding protein appD PH1959 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 14590923 Common - methionine synthase PH1089 150 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 14590398 Common - hypothetical protein PH0488 40 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 14591554 Common - hypothetical protein PH1801 75 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 14591430 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta PH1661 120 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 14590665 Nonpathogen - hypothetical protein PH0797 1 None None None 14590769 Nonpathogen - hypothetical protein PH0915 2 None None None 14590896 Nonpathogen - hypothetical protein PH1059 26 COG2090 COG2090, Uncharacterized protein conserved in archaea Function unknown 14591220 Common - putative monovalent cation/H+ antiporter subunit E PH1427 68 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 14591751 Nonpathogen - Lipoate-protein ligase A PH1620a 6 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 14591480 Common - acetylglutamate kinase PH1718 199 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 33359416 Nonpathogen - hypothetical protein PH1595.1n 1 None None None 14590311 Nonpathogen - hypothetical protein PH0404 2 None None None 14591297 Common - N-ethylammeline chlorohydrolase PH1515 174 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 14590162 Nonpathogen - hypothetical protein PH0231 26 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 14591324 Common rps12P 30S ribosomal protein S12P PH1542 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 14590325 Nonpathogen - hypothetical protein PH0410 1 None None None 14590434 Nonpathogen - hypothetical protein PH0533 2 None None None 14591015 Nonpathogen - hypothetical protein PH1190 2 None None None 14590536 Nonpathogen - hypothetical protein PH0646 1 None None None 14590457 Common - hypothetical protein PH0557 226 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 14591271 Nonpathogen - hypothetical protein PH1486 1 None None None 14590289 Common - glucose-1 phosphate transferase PH0380 233 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 14590507 Common - hypothetical N-acetylmuramoyl-L-alanine amidase modifier precursor PH0614 11 COG2247 LytB, Putative cell wall-binding domain Cell envelope biogenesis, outer membrane 14590974 Common gcvT glycine cleavage system aminomethyltransferase T PH1146 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 14590995 Nonpathogen - hypothetical protein PH1169 1 None None None 14590004 Common - dolichol-phosphate mannosyltransferase PH0051 209 COG2246 COG2246, Predicted membrane protein Function unknown 33359357 Nonpathogen - hypothetical protein PH1044.1n 1 None None None 14591675 Common - hypothetical protein PH1933 20 COG0456 RimI, Acetyltransferases General function prediction only 33359402 Nonpathogen - hypothetical protein PH1395.1n 2 None None None 33359316 Nonpathogen - hypothetical protein PH0687.1n 1 None None None 14591416 Nonpathogen - hypothetical protein PH1646 1 None None None 14591381 Common - hypothetical protein PH1606 11 COG3463 COG3463, Predicted membrane protein Function unknown 14590347 Common - hypothetical protein PH0432 33 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 33359389 Nonpathogen - hypothetical protein PH1297.2n 1 None None None 14590479 Nonpathogen - hypothetical protein PH0583 2 None None None 14590318 Nonpathogen - hypothetical protein PHS009 1 None None None 14590787 Common - hypothetical protein PH0935 53 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 14590013 Nonpathogen - 30S ribosomal protein S3Ae PH0060 34 COG1890 RPS1A, Ribosomal protein S3AE Translation, ribosomal structure and biogenesis 14590462 Common - hypothetical protein PH0563 14 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 33359281 Nonpathogen - hypothetical protein PH0389.1n 8 None None None 14590404 Nonpathogen - hypothetical protein PH0498 19 COG1423 COG1423, ATP-dependent DNA ligase, homolog of eukaryotic ligase III DNA replication, recombination, and repair 14590789 Common - hypothetical protein PH0937 126 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 14591302 Common - transcriptional regulator PH1519 176 COG1522 Lrp, Transcriptional regulators Transcription 33359436 Common - hypothetical 4Fe-4S ferredoxin PH1871.1n 31 COG1141 Fer, Ferredoxin Energy production and conversion 14591656 Common - hypothetical protein PH1914 60 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 14591206 Common - dipeptide transport system permease protein dppB PH1410 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 14590996 Nonpathogen - hypothetical protein PH1170 1 None None None 14590340 Nonpathogen - hypothetical protein PH0423 1 None None None 14590488 Nonpathogen - hypothetical protein PH0592 2 None None None 14591516 Nonpathogen rpl19e 50S ribosomal protein L19e PH1759 34 COG2147 RPL19A, Ribosomal protein L19E Translation, ribosomal structure and biogenesis 161350013 Common - D-cysteine desulfhydrase PH0054 70 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 14590735 Common - ferredoxin--NADP(+) reductase subunit alpha PH0878 69 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 14590584 Nonpathogen nusA transcription elongation factor NusA-like protein PH0706 13 COG0195 NusA, Transcription elongation factor Transcription 14590999 Nonpathogen - hypothetical protein PH1173 1 None None None 33359284 Nonpathogen - hypothetical protein PHS010.2n 1 None None None 14591588 Nonpathogen - hypothetical protein PH1839 19 COG1458 COG1458, Predicted DNA-binding protein containing PIN domain General function prediction only 14590757 Nonpathogen - hypothetical protein PH0901 2 None None None 14590330 Nonpathogen - hypothetical protein PH0412 1 None None None 14591060 Nonpathogen - hypothetical protein PH1241 2 None None None 14591550 Nonpathogen - hypothetical protein PH1795 1 None None None 33359347 Nonpathogen mnhC putative monovalent cation/H+ antiporter subunit C PH0941a 2 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 14591351 Nonpathogen - hypothetical protein PH1570 2 None None None 14590599 Common - amino acid amidohydrolase PH0722 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 14591723 Nonpathogen - hypothetical protein PH1988 5 None None None 14591021 Nonpathogen - hypothetical protein PH1198 3 COG1470 COG1470, Predicted membrane protein Function unknown 14591108 Common - hypothetical protein PH1298 6 None None None 14590300 Common - hypothetical protein PH0392 17 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 14591530 Common rps19p 30S ribosomal protein S19P PH1774 248 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 14590677 Common - oligopeptide transport ATP-binding protein APPD PH0810 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 14590724 Nonpathogen - transcription initiation factor IIB PH0864 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 14591101 Common - cytochrome-c3 hydrogenase alpha chain PH1290 31 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 14591523 Nonpathogen rpl24p 50S ribosomal protein L24P PH1767 34 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 14590277 Common - galactokinase PH0369 90 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 14590723 Common - hypothetical protein PH0863 109 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 14590746 Nonpathogen - hypothetical protein PH0889 1 COG4273 COG4273, Uncharacterized conserved protein Function unknown 14591054 Common - ferrichrome transport ATP-binding protein PH1235 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 14590849 Nonpathogen - transcription factor PH1009 34 COG2101 SPT15, TATA-box binding protein (TBP), component of TFIID and TFIIIB Transcription 33359260 Nonpathogen - Cyclic 2,3-diphosphoglycerate synthase PH0149.1n 7 COG2403 COG2403, Predicted GTPase General function prediction only 14591221 Common - putative monovalent cation/H+ antiporter subunit G PH1428 19 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 14590866 Common - hypothetical protein PH1028 39 COG2521 COG2521, Predicted archaeal methyltransferase General function prediction only 33359323 Nonpathogen - hypothetical protein PH0714.1n 1 None None None 33359413 Nonpathogen - hypothetical protein PH1540.1n 2 None None None 14591506 Common - D-nopaline dehydrogenase PH1749 130 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 14590178 Common - hypothetical protein PH0249 157 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 14590736 Common - hydrogenase expression/formation protein hypD PH0879 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 14590473 Common - damage-inducible protein PH0577 179 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 33359325 Common - hypothetical protein PH0718.1n 19 COG1695 COG1695, Predicted transcriptional regulators Transcription 14589990 Common - morphine 6-dehydrogenase PH0031 195 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 14590886 Common - hypothetical protein PH1049 16 None None None 14591458 Common tdk thymidylate kinase PH1695 239 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 14591253 Common - glutamyl-tRNA(Gln) amidotransferase subunit E PH1464 210 COG2511 GatE, Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) Translation, ribosomal structure and biogenesis 33359398 Nonpathogen - hypothetical protein PH1359.2n 2 None None None 14591384 Nonpathogen - pyruvoyl-dependent arginine decarboxylase PH1609 21 COG1945 COG1945, Uncharacterized conserved protein Function unknown 14590984 Common - hydroxyethylthiazole kinase PH1157 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 33359291 Nonpathogen - hypothetical protein PH0419.1n 4 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 14591103 Common - cytochrome-c3 hydrogenase delta chain PH1292 23 COG1941 FrhG, Coenzyme F420-reducing hydrogenase, gamma subunit Energy production and conversion 33359253 Nonpathogen - hypothetical protein PH0067 2 None None None 14590149 Nonpathogen - hypothetical protein PHS002 1 None None None 14590382 Nonpathogen - hypothetical protein PHS020 8 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 14591041 Common - hypothetical protein PH1222 54 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 14591761 Nonpathogen - Predicted nucleic acid-binding protein, contains PIN domain PHS031a 7 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 14589988 Common ubiA prenyltransferase UbiA-like protein PH0027 103 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 14591212 Common - hypothetical protein PH1416 38 COG2520 COG2520, Predicted methyltransferase General function prediction only 14590025 Nonpathogen - hypothetical protein PH0071 35 COG1628 COG1628, Uncharacterized conserved protein Function unknown 14590171 Common - amidophosphoribosyltransferase PH0240 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 14591016 Nonpathogen - hypothetical protein PH1191 3 None None None 14589985 Common - sugar transport membrane protein PH0024 166 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 14590768 Common - hypothetical protein PH0914 9 COG1695 COG1695, Predicted transcriptional regulators Transcription 14591154 Common - GMP synthase subunit B PH1347 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 14591431 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit alpha PH1662 124 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 14590936 Nonpathogen - hypothetical protein PH1105 34 COG1736 DPH2, Diphthamide synthase subunit DPH2 Translation, ribosomal structure and biogenesis 14591051 Nonpathogen - hypothetical protein PH1232 1 None None None 33359414 Common hypA hydrogenase nickel incorporation protein PH1581 27 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 14591635 Common - hypothetical protein PH1891 113 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 14591711 Common - V-type ATP synthase subunit B PH1974 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 14591238 Common - NADH dehydrogenase subunit C PH1448 90 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 14590566 Common - pyruvate ferredoxin oxidoreductase subunit beta PH0685 84 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 14591197 Common - putative deoxyhypusine synthase PH1397 58 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 14591196 Nonpathogen - hypothetical protein PH1395 4 None None None 14590384 Nonpathogen - hypothetical protein PH0471 2 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 14590570 Common - hypothetical protein PH0691 58 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 14591562 Common - glucose-1-dehydrogenase PH1809 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 33359275 Nonpathogen - hypothetical protein PH0358.1n 2 None None None 14590558 Common - acetyl-CoA acetyltransferase PH0676 101 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 14589971 Common - hypothetical protein PH0009 33 COG1479 COG1479, Uncharacterized conserved protein Function unknown 14590990 Common - hypothetical protein PH1163 107 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 33359271 Nonpathogen - hypothetical protein PH0317.1n 2 None None None 14591707 Common - chemoreceptor protein PH1970 92 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 14591661 Nonpathogen - hypothetical protein PH1919 2 COG1522 Lrp, Transcriptional regulators Transcription 14591618 Nonpathogen - hypothetical protein PH1871 1 None None None 14590935 Nonpathogen - hypothetical protein PH1104 1 None None None 14591600 Nonpathogen - hypothetical protein PH1854 3 COG3677 COG3677, Transposase and inactivated derivatives DNA replication, recombination, and repair 33359379 Common - hypothetical protein PH1244.1n 37 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 14591607 Nonpathogen - hypothetical protein PH1860 1 None None None 14590604 Nonpathogen - hypothetical protein PH0727 8 COG4028 COG4028, Predicted P-loop ATPase/GTPase General function prediction only 14590054 Common - hypothetical protein PH0104 66 COG1409 Icc, Predicted phosphohydrolases General function prediction only 14591167 Common - proline permease PH1361 182 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 14591473 Nonpathogen - hypothetical protein PH1710 22 COG1412 COG1412, Uncharacterized proteins of PilT N-term./Vapc superfamily General function prediction only 161350005 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit alpha PH1666 118 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 14590607 Nonpathogen - hypothetical protein PH0730 7 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 14590631 Common thyX FAD-dependent thymidylate synthase PH0762 59 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 14591243 Common - putative monovalent cation/H+ antiporter subunit C PH1453 69 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 33359308 Nonpathogen - hypothetical protein PH0604.1n 1 None None None 14591537 Common - hypothetical protein PH1780 142 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 14590123 Nonpathogen - hypothetical protein PH0188 2 None None None 14590242 Common - hypothetical protein PH0325 93 COG1814 COG1814, Uncharacterized membrane protein Function unknown 14590420 Common - hypothetical protein PH0518 80 COG0730 COG0730, Predicted permeases General function prediction only 14591408 Nonpathogen - DNA-directed RNA polymerase subunit D PH1637 44 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 14591590 Common - transitional endoplasmic reticulum ATPase PH1840 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 33359301 Nonpathogen - putative flagella-related protein PH0553.1n 2 COG3353 FlaF, Putative archaeal flagellar protein F Cell motility and secretion 14590698 Nonpathogen - hypothetical protein PH0832 2 None None None 14591386 Nonpathogen - hypothetical protein PH1611 1 None None None 14591705 Common - hypothetical protein PH1968 17 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 14591375 Common - thymidine phosphorylase PH1598 188 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 14590437 Common - hypothetical protein PH0536 22 COG2517 COG2517, Predicted RNA-binding protein containing a C-terminal EMAP domain General function prediction only 14590636 Common - SOJ protein PH0768 232 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 14590224 Common - hypothetical protein PH0303 75 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 33359336 Common - hypothetical protein PH0837.1n 24 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 33359384 Nonpathogen - hypothetical protein PH1263.2n 1 None None None 33359376 Nonpathogen - hypothetical protein PH1210.1n 2 None None None 14590430 Nonpathogen - translation initiation factor IF-6 PH0528 33 COG1976 TIF6, Translation initiation factor 6 (eIF-6) Translation, ribosomal structure and biogenesis 14591581 Nonpathogen - hypothetical protein PH1831 2 None None None 14590688 Common - hypothetical protein PH0821 116 COG1511 COG1511, Predicted membrane protein Function unknown 14591370 Common - transcriptional regulator PH1592 171 COG1522 Lrp, Transcriptional regulators Transcription 14590429 Nonpathogen rplX 50S ribosomal protein LX PHS021 5 COG2157 RPL20A, Ribosomal protein L20A (L18A) Translation, ribosomal structure and biogenesis 14590702 Common - hypothetical protein PH0837 36 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 14590204 Common - hypothetical protein PH0280 31 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 14590672 Nonpathogen - hypothetical protein PH0805 1 None None None 14591463 Nonpathogen - hypothetical protein PH1700 12 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 14590084 Common - hypothetical protein PH0142 155 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 14590763 Nonpathogen - hypothetical protein PHS027 4 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 33359359 Nonpathogen - hypothetical protein PH1076 1 None None None 14590031 Nonpathogen - hypothetical protein PH0077 1 None None None 14590213 Common hisS histidyl-tRNA synthetase PH0290 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 14590517 Common - hypothetical protein PH0626 198 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 14591569 Common - hypothetical protein PH1818 153 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 14590038 Common - hypothetical protein PH0085 165 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 14591557 Common - hypothetical protein PH1804 16 COG1224 TIP49, DNA helicase TIP49, TBP-interacting protein Transcription 33359340 Nonpathogen - hypothetical protein PH0894.1n 1 None None None 14590124 Nonpathogen - hypothetical protein PH0189 22 COG1784 COG1784, Predicted membrane protein Function unknown 14591689 Common - hypothetical protein PH1948 44 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 14590375 Common - nicotinamide-nucleotide adenylyltransferase PH0464 52 COG1056 NadR, Nicotinamide mononucleotide adenylyltransferase Coenzyme metabolism 14591333 Common - exosome complex exonuclease Rrp41 PH1549 233 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 14590441 Common - S-adenosyl-L-homocysteine hydrolase PH0540 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 14590914 Common - hypothetical protein PH1079 55 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 14590341 Common - hypothetical protein PH0424 51 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 14590413 Common - hypothetical protein PH0510 233 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 14590869 Nonpathogen - hypothetical protein PH1031 2 None None None 14590415 Common - hypothetical protein PH0512 58 COG0478 COG0478, RIO-like serine/threonine protein kinase fused to N-terminal HTH domain Signal transduction mechanisms 14590871 Nonpathogen - hypothetical protein PHS030 1 None None None 14590456 Common - flagellar accessory protein FlaH PH0556 24 COG2874 FlaH, Predicted ATPases involved in biogenesis of archaeal flagella Cell motility and secretion / Intracellular trafficking and secretion 14590686 Common - methyltransferase PH0819 162 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 14591673 Nonpathogen - hypothetical protein PH1931 23 COG1888 COG1888, Uncharacterized protein conserved in archaea Function unknown 14590663 Nonpathogen - hypothetical protein PH0795 22 COG1645 COG1645, Uncharacterized Zn-finger containing protein General function prediction only 14591178 Common - ribose-5-phosphate isomerase A PH1375 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 161349998 Common - short chain dehydrogenase PH1901 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 14591071 Common - nodulation protein PH1253 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 14591304 Nonpathogen - hypothetical protein PH1521 1 None None None 14590975 Nonpathogen - hypothetical protein PH1147 1 None None None 14591294 Common - hypothetical protein PH1512 150 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 33359434 Nonpathogen - hypothetical protein PH1868.1n 1 None None None 14590215 Nonpathogen - hypothetical protein PH0293 1 None None None 14590282 Nonpathogen - hypothetical protein PH0374 14 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 14591630 Common - phosphoserine phosphatase PH1885 105 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 14589993 Nonpathogen - hypothetical protein PH0035 1 None None None 33359265 Nonpathogen - hypothetical protein PH0216.1n 1 None None None 14590591 Common - hypothetical protein PH0713 129 COG0432 COG0432, Uncharacterized conserved protein Function unknown 14590256 Common - hypothetical protein PH0344 219 COG0486 ThdF, Predicted GTPase General function prediction only 33359365 Nonpathogen - hypothetical protein PH1135 2 COG2886 COG2886, Uncharacterized small protein Function unknown 14590755 Nonpathogen - hypothetical protein PH0899 1 None None None 14591637 Nonpathogen - replication factor A PH1893 18 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 14591654 Nonpathogen - hypothetical protein PH1911 4 None None None 14591420 Common rnhB ribonuclease HII PH1650 228 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 14590917 Nonpathogen - hypothetical protein PH1082 1 None None None 14591511 Common - preprotein translocase subunit SecY PH1754 89 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 14590320 Nonpathogen - hypothetical protein PHS011 7 COG5428 COG5428, Uncharacterized conserved small protein Function unknown 14590894 Common - hypothetical protein PH1057 20 COG1633 COG1633, Uncharacterized conserved protein Function unknown 33359306 Common - putative molybdopterin converting factor, subunit 1 PH0581.1n 47 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 14590518 Common - hypothetical protein PH0627 128 COG0327 COG0327, Uncharacterized conserved protein Function unknown 14590527 Common cysS cysteinyl-tRNA synthetase PH0636 246 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 33359406 Common - putative monovalent cation/H+ antiporter subunit F PH1455.1n 82 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 14590190 Nonpathogen - DNA repair and recombination protein RadA PH0263 35 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 14591326 Nonpathogen - 50S ribosomal protein L30e PHS043 29 COG1911 RPL30, Ribosomal protein L30E Translation, ribosomal structure and biogenesis 14590927 Common - translation initiation factor IF-2 PH1095 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 14590547 Nonpathogen - hypothetical protein PH0663 24 COG2178 COG2178, Predicted RNA-binding protein of the translin family Translation, ribosomal structure and biogenesis 14589964 Common rpl11p 50S ribosomal protein L11P PH0001 244 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 14591342 Nonpathogen - hypothetical protein PH1559 2 None None None 14591532 Common rplW 50S ribosomal protein L23 PHS049 217 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 14591097 Common - putative acetyl-CoA carboxylase biotin carboxyl carrier protein subunit PH1284 22 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 14591570 Common - hypothetical protein PH1819 37 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 14591276 Nonpathogen - hypothetical protein PH1491 1 None None None 14591187 Common - ATP-dependent transporter YCF16 PH1384 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 14591579 Nonpathogen - 50S ribosomal protein L35Ae PHS052 9 COG2451 COG2451, Ribosomal protein L35AE/L33A Translation, ribosomal structure and biogenesis 14590625 Common - sugar transport system permease protein PH0755 153 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 14591201 Common - proteasome beta subunit precursor PH1402 50 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 14591120 Common - hypothetical protein PH1309 74 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 33359288 Nonpathogen - hypothetical protein PHS014.3n 2 None None None 14590392 Nonpathogen - hypothetical protein PH0480 1 None None None 14591263 Common egsA NAD(P)-dependent glycerol-1-phosphate dehydrogenase PH1475 142 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 14591411 Common rps13p 30S ribosomal protein S13P PH1641 157 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 14590647 Nonpathogen - hypothetical protein PH0779 2 None None None 14590104 Nonpathogen - hypothetical protein PH0167 14 COG1332 COG1332, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 33359314 Nonpathogen - hypothetical protein PH0673.1n 3 None None None 14590183 Nonpathogen - hypothetical protein PH0255 24 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 14591008 Nonpathogen - hypothetical protein PH1183 2 None None None 14590295 Common - hypothetical protein PH0387 94 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 14591136 Nonpathogen - 30S ribosomal protein S19e PH1325 34 COG2238 RPS19A, Ribosomal protein S19E (S16A) Translation, ribosomal structure and biogenesis 14591115 Common - hypothetical protein PH1305 179 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 14591389 Common - glycyl-tRNA synthetase PH1614 98 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 14590822 Common - hypothetical protein PH0977 35 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14590959 Nonpathogen - hypothetical protein PH1130 3 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 14591672 Common - hypothetical protein PH1930 46 COG4189 COG4189, Predicted transcriptional regulator Transcription 14590512 Nonpathogen - hypothetical protein PH0620 26 COG2433 COG2433, Uncharacterized conserved protein Function unknown 14590785 Common - Na(+)/H(+) antiporter PH0934 146 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 14590133 Nonpathogen - hypothetical protein PH0199 10 COG1522 Lrp, Transcriptional regulators Transcription 14590888 Nonpathogen - hypothetical protein PH1051 1 None None None 14590156 Nonpathogen - hypothetical protein PH0225 3 None None None 14590776 Common - hypothetical protein PH0922 26 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 14590312 Nonpathogen - hypothetical protein PH0405 2 None None None 14591478 Common - acetyl-lysine deacetylase PH1715 82 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 14590798 Common - putative monovalent cation/H+ antiporter subunit E PH0946 59 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 14590011 Nonpathogen rps15p 30S ribosomal protein S15P PH0058 34 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 14590400 Common - chemotaxis protein PH0491 162 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 14591065 Nonpathogen - hypothetical protein PHS033 10 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 14590499 Nonpathogen - hypothetical protein PH0603 1 None None None 14590805 Nonpathogen - hypothetical protein PH0953 1 None None None 14590831 Common - hypothetical protein PH0986 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 14591208 Common - dipeptide transport ATP-binding protein dppD PH1412 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 14591232 Common - hypothetical protein PH1441 37 COG4027 COG4027, Uncharacterized protein conserved in archaea Function unknown 14590846 Common - hypothetical protein PH1004 20 None None None 14590193 Common - hypothetical inosine-5'-monophosphate dehydrogenase related protein II PH0267 168 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 14591392 Common - UDP-N-acetylglucosamine 2-epimerase PH1617 154 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 14591753 Nonpathogen GAR1 H/ACA RNA-protein complex component Gar1 PH1745a 16 COG3277 GAR1, RNA-binding protein involved in rRNA processing Translation, ribosomal structure and biogenesis 14591739 Nonpathogen - hypothetical protein PH0209a 3 COG1873 COG1873, Uncharacterized conserved protein Function unknown 14590500 Nonpathogen - hypothetical protein PH0604 1 None None None 14590949 Nonpathogen - hypothetical protein PH1119 1 None None None 14590072 Common - hypothetical protein PH0128 40 COG1637 COG1637, Predicted nuclease of the RecB family DNA replication, recombination, and repair 14590113 Nonpathogen - hypothetical protein PH0177 2 None None None 14591615 Common - nicotinate phosphoribosyltransferase PH1868 117 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 14591145 Nonpathogen - hypothetical protein PH1338 2 COG1991 COG1991, Uncharacterized conserved protein Function unknown 14591487 Common - hypothetical protein PH1729 65 COG2510 COG2510, Predicted membrane protein Function unknown 14590478 Common - molybdopterin biosynthesis moea protein PH0582 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 33359312 Nonpathogen - hypothetical protein PH0645.1n 4 None None None 14590652 Common - DNA-3-methyladenine glycosidase PH0784 60 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 14590909 Common ppnK inorganic polyphosphate/ATP-NAD kinase PH1074 238 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 161349993 Nonpathogen - DNA-directed RNA polymerase subunit P PHS056 6 COG1996 RPC10, DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) Transcription 14591648 Nonpathogen - hypothetical protein PH1903 29 COG2237 COG2237, Predicted membrane protein Function unknown 14590142 Nonpathogen - hypothetical protein PH0209 16 COG1255 COG1255, Uncharacterized protein conserved in archaea Function unknown 14590066 Nonpathogen - DNA polymerase II large subunit PH0121 25 COG1933 COG1933, Archaeal DNA polymerase II, large subunit DNA replication, recombination, and repair 33359390 Nonpathogen - hypothetical protein PH1300.1n 1 None None None 14590302 Nonpathogen - hypothetical protein PH0394 1 None None None 14590155 Common lysK lysyl-tRNA synthetase PH0224 78 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 14590714 Common - hypothetical protein PH0854 201 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 14591224 Common - putative monovalent cation/H+ antiporter subunit C PH1430 29 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 14590070 Nonpathogen - hypothetical protein PH0126 34 COG1938 COG1938, Archaeal enzymes of ATP-grasp superfamily General function prediction only 14589996 Common - modification methylase PH0039 109 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 33359293 Nonpathogen - hypothetical protein PH0448 13 COG2411 COG2411, Uncharacterized conserved protein Function unknown 14590574 Common - hypothetical protein PH0695 12 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 14590683 Common - hypothetical protein PH0816 87 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 14591184 Common - translation initiation factor IF-5A PH1381 37 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 14590864 Common - hypothetical protein PH1025 84 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 14590389 Nonpathogen - hypothetical protein PH0477 1 None None None 14590189 Nonpathogen - hypothetical protein PH0262 7 COG3371 COG3371, Predicted membrane protein Function unknown 14590524 Nonpathogen rpl10e 50S ribosomal protein L10e PH0633 34 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 14590928 Nonpathogen - hypothetical protein PH1097 1 None None None 14591504 Nonpathogen - hypothetical protein PH1747 2 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 14590316 Nonpathogen - hypothetical protein PH0409 3 None None None 14590986 Common - cytosine permease PH1159 78 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 14590279 Common - hypothetical protein PH0371 14 COG2253 COG2253, Uncharacterized conserved protein Function unknown 14591250 Nonpathogen - hypothetical protein PH1461 1 None None None 14590938 Common - hypothetical protein PH1107 31 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 14590116 Common - hypothetical protein PH0181 120 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 14591043 Common - hypothetical protein PH1224 36 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 14591421 Common - membrane protein PH1651 156 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 14590904 Common - hypothetical protein PH1067 24 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14591014 Common - hypothetical protein PH1189 6 COG2433 COG2433, Uncharacterized conserved protein Function unknown 14589983 Common - sugar-binding transport ATP-binding protein PH0022 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 14591404 Nonpathogen - DNA-directed RNA polymerase subunit N PH1632 34 COG1644 RPB10, DNA-directed RNA polymerase, subunit N (RpoN/RPB10) Transcription 14591140 Common - ATP-dependent helicase PH1329 238 COG1201 Lhr, Lhr-like helicases General function prediction only 14590380 Nonpathogen - hypothetical protein PH0468 2 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 14590232 Common valS valyl-tRNA synthetase PH0314 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 14591169 Common - sarcosine oxidase PH1364 151 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 14590448 Nonpathogen - flagellin PH0548 8 COG1681 FlaB, Archaeal flagellins Cell motility and secretion 14590744 Nonpathogen - hypothetical protein PH0887 1 None None None 33359362 Nonpathogen - hypothetical protein PH1126.1n 1 None None None 33359392 Nonpathogen - hypothetical protein PH1325.1n 4 None None None 14590364 Common - hypothetical protein PH0450 136 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 14590241 Nonpathogen purP hypothetical protein PH0324 20 COG1759 COG1759, ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) General function prediction only 14590095 Nonpathogen - hypothetical protein PH0156 3 None None None 14591160 Common - hypothetical protein PH1354 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 14590297 Nonpathogen - hypothetical protein PH0389 7 COG4113 COG4113, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 14590023 Common - hypothetical protein PH0069 204 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 14591541 Common - hypothetical protein PH1783 70 COG1469 COG1469, Uncharacterized conserved protein Function unknown 14590344 Nonpathogen - hypothetical protein PH0428 1 None None None 14590361 Common - hypothetical protein PH0447 4 COG4043 COG4043, Uncharacterized conserved protein Function unknown 33359263 Common - Putative ferredoxin PH0180.1n 61 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 14590820 Common - hypothetical protein PH0975 98 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 14591700 Common - oligopeptide transport system permease protein appB PH1961 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 14591679 Nonpathogen - hypothetical protein PH1937 2 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 161350003 Common rpl6p 50S ribosomal protein L6P PH1763 145 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 14590660 Nonpathogen - hypothetical protein PH0792 20 COG1618 COG1618, Predicted nucleotide kinase Nucleotide transport and metabolism 14590726 Nonpathogen - hypothetical protein PH0867 1 None None None 14590534 Common - hypothetical protein PH0644 127 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 14591288 Nonpathogen - hypothetical protein PH1505 8 COG1504 COG1504, Uncharacterized conserved protein Function unknown 14591716 Nonpathogen - V-type ATP synthase subunit K PH1980 6 None None None 14591127 Nonpathogen - hypothetical protein PH1315 2 None None None 14591156 Common - thiamin-binding periplasmic protein precursor PH1349 134 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 33359424 Nonpathogen - hypothetical protein PH1743.1n 2 None None None 14591622 Common - hypothetical protein PH1875 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 33359327 Nonpathogen - hypothetical protein PH0766.1n 2 None None None 14591409 Common rps11p 30S ribosomal protein S11P PH1638 80 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 14590530 Common - phosphate permease PH0640 173 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 14590708 Common - dihydrodipicoline synthase PH0847 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 14591396 Common - hypothetical protein PH1621 22 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 14590694 Common - nitrite reductase PH0827 159 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 33359350 Nonpathogen - hypothetical protein PH0973 3 None None None 14590258 Nonpathogen - hypothetical protein PH0346 2 None None None 33359334 Nonpathogen - hypothetical protein PH0817.1n 1 None None None 14590471 Common - alanyl-tRNA synthetase PH0574 100 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 14590426 Common - hypothetical protein PH0524 134 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 14590377 Common - thermostable carboxypeptidase PH0465 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 14591374 Common - hypothetical protein PH1596 225 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 14590427 Common - translation-associated GTPase PH0525 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 33359251 Nonpathogen - hypothetical protein PH0065.2n 2 None None None 14590691 Common - hypothetical protein PH0824 106 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 14590121 Common - hypothetical protein PH0186 62 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 14590615 Nonpathogen - hypothetical protein PH0742 2 None None None 14591214 Nonpathogen - hypothetical protein PH1419 1 None None None 14591740 Common - Acylphosphatase PH0305a 149 COG1254 AcyP, Acylphosphatases Energy production and conversion 33359342 Nonpathogen - hypothetical protein PH0919 3 COG1688 COG1688, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 14591249 Common - fructokinase PH1459 175 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 14590670 Common - hypothetical protein PH0803 42 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 14591316 Nonpathogen - hypothetical protein PH1534 1 None None None 14591539 Common - hypothetical protein PH1782 90 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 14590184 Common - hypothetical protein PH0256 45 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 14590873 Common - hypothetical protein PH1034 37 COG1378 COG1378, Predicted transcriptional regulators Transcription 14591660 Common - hypothetical protein PH1918 33 COG1839 COG1839, Uncharacterized conserved protein Function unknown 14590068 Nonpathogen cdc6 cell division control protein 6 PH0124 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 14591552 Nonpathogen - hypothetical protein PH1797 12 COG1354 COG1354, Uncharacterized conserved protein Function unknown 14590036 Common - agmatinase PH0083 138 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 14590733 Common - hypothetical protein PH0874 60 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 14591099 Common - methylmalonyl-CoA decarboxylase alpha chain PH1287 218 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 14591090 Common - malate oxidoreductase PH1275 189 COG0281 SfcA, Malic enzyme Energy production and conversion 14591335 Nonpathogen - hypothetical protein PH1552 34 COG1500 COG1500, Predicted exosome subunit Translation, ribosomal structure and biogenesis 14590958 Nonpathogen - hypothetical protein PH1129 1 None None None 14590339 Nonpathogen - hypothetical protein PH0422 1 None None None 14591559 Common - hypothetical protein PH1806 109 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 33359374 Nonpathogen - hypothetical protein PH1204.1n 2 COG1414 IclR, Transcriptional regulator Transcription 14590572 Nonpathogen - hypothetical protein PH0693 1 None None None 33359277 Nonpathogen - hypothetical protein PH0377.1n 1 None None None 14591513 Nonpathogen rpl30p 50S ribosomal protein L30P PH1756 34 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 14590717 Common - threonine synthase PH0857 205 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 14591033 Common - hypothetical protein PH1213 215 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 14591185 Common - hypothetical protein PH1382 80 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 14591709 Common - V-type ATP synthase subunit D PH1972 49 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 14591194 Nonpathogen - hypothetical protein PH1392 3 None None None 14591362 Nonpathogen - peptide chain release factor 1 PH1584 35 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 14591339 Nonpathogen - hypothetical protein PH1556 1 None None None 14590353 Common - adenylosuccinate synthetase PH0438 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 14591564 Common moaC putative molybdenum cofactor biosynthesis protein C PH1811 196 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 14590248 Nonpathogen - hypothetical protein PH0333 2 COG1520 COG1520, FOG: WD40-like repeat Function unknown 14591251 Nonpathogen - hypothetical protein PH1462 5 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 14591236 Common - NADH dehydrogenase subunit I PH1446 186 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 14591747 Nonpathogen thiS sulfur carrier protein ThiS PH1106a 7 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 14590803 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase PH0951 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 14590409 Common - oligopeptide transport system permease protein AppB PH0503 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 14590370 Common - hypothetical protein PH0459 143 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 33359273 Nonpathogen - hypothetical tRNA-intron endonuclease PH0317.3n 1 COG5378 COG5378, Predicted nucleotide-binding protein General function prediction only 14590286 Nonpathogen - hypothetical protein PHS007 1 None None None 14590484 Nonpathogen - hypothetical protein PH0588 3 None None None 14591106 Common - proton glutamate symport protein PH1295 165 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 14590056 Common - alanyl-tRNA synthetase PH0108 152 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 14590435 Common - hypothetical protein PH0534 73 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 14590700 Common - pyruvate carboxylase subunit B PH0834 159 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 14591056 Common - hypothetical protein PH1237 87 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 14591605 Common - hypothetical protein PH1858 76 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 14590048 Nonpathogen - hypothetical protein PH0097 2 None None None 14590609 Nonpathogen - hypothetical protein PH0734 34 COG2016 COG2016, Predicted RNA-binding protein (contains PUA domain) Translation, ribosomal structure and biogenesis 14590050 Common - hypothetical protein PH0099 109 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 14590264 Common - hypothetical protein PH0354 39 COG1679 COG1679, Uncharacterized conserved protein Function unknown 14591475 Common - hypothetical protein PH1712 106 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 33359411 Nonpathogen - hypothetical protein PH1526 1 None None None 14590623 Common - hypothetical protein PH0753 122 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 14590172 Common asnC asparaginyl-tRNA synthetase PH0241 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 14591011 Nonpathogen - hypothetical protein PH1186 3 None None None 33359401 Nonpathogen - hypothetical protein PH1380 2 None None None 14591639 Nonpathogen - hypothetical protein PH1895 2 COG2433 COG2433, Uncharacterized conserved protein Function unknown 14590222 Common - hypothetical protein PH0300 159 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 14590586 Nonpathogen - hypothetical protein PH0708 2 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 14591046 Common - hypothetical protein PH1227 25 COG1433 COG1433, Uncharacterized conserved protein Function unknown 14591125 Common - thiamine biosynthesis protein ThiI PH1313 90 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 33359445 Common rpl1P 50S ribosomal protein L1P PH2000 246 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 14590892 Common - hypothetical protein PH1055 33 COG1522 Lrp, Transcriptional regulators Transcription 14591755 Common MUS81 ERCC4-like helicase/ERCC4-type nuclease PH1896m 195 COG1111 MPH1, ERCC4-like helicases DNA replication, recombination, and repair 14589977 Common - L-aspartate oxidase PH0015 226 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 33359290 Nonpathogen - hypothetical protein PHS014.5n 4 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 14590654 Nonpathogen - hypothetical protein PH0785 2 None None None 14590329 Nonpathogen - hypothetical protein PHS018 2 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 33359310 Nonpathogen - hypothetical protein PH0630.1n 5 None None None 14591604 Nonpathogen - hypothetical protein PH1857 2 None None None 14591345 Common - DNA topoisomerase VI subunit A PH1563 34 COG1697 COG1697, DNA topoisomerase VI, subunit A DNA replication, recombination, and repair 14590719 Common - putative ATPase RIL PH0859 249 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 33359319 Nonpathogen - hypothetical protein PH0696.2n 4 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 14590041 Nonpathogen - hypothetical protein PH0089 3 COG1822 COG1822, Predicted archaeal membrane protein Function unknown 14591328 Common - DNA-directed RNA polymerase subunit alpha PH1545 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 14590106 Nonpathogen - hypothetical protein PH0169 1 None None None 14590661 Common - hypothetical protein PH0793 37 COG2520 COG2520, Predicted methyltransferase General function prediction only 14589966 Common - cell division protein FtsZ PH0003 233 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 14590919 Common - flavoprotein PH1085 82 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 14590568 Common - cell division control protein (transitional endoplasmic reticulum ATPase) PH0687 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 14591577 Nonpathogen - hypothetical protein PH1827 32 COG1829 COG1829, Predicted archaeal kinase (sugar kinase superfamily) General function prediction only 14590812 Common leuS leucyl-tRNA synthetase PH0965 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 14591173 Common - hypothetical protein PH1369 24 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 14590018 Nonpathogen - hypothetical protein PH0064 1 None None None 14590165 Common - hypothetical protein PH0234 14 COG2516 COG2516, Biotin synthase-related enzyme General function prediction only 14590867 Nonpathogen - hypothetical protein PH1029 1 None None None 14590794 Common - putative monovalent cation/H+ antiporter subunit B PH0942 23 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 14591491 Common - aspartate racemase PH1733 86 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 14590453 Nonpathogen - hypothetical protein PH0553 9 COG3351 FlaD, Putative archaeal flagellar protein D/E Cell motility and secretion 14590407 Common - beta-mannosidase PH0501 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 33359348 Common - putative monovalent cation/H+ antiporter subunit F PH0944.1n 27 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 33359408 Nonpathogen - hypothetical protein PH1471 29 COG1709 COG1709, Predicted transcriptional regulator Transcription 14591443 Common - hypothetical protein PH1679 6 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 14591357 Common - hypothetical protein PH1579 153 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 14591426 Common - hypothetical protein PH1657 16 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 14590961 Common - GTP-binding protein hflX PH1132 239 COG2262 HflX, GTPases General function prediction only 161349996 Nonpathogen rpl44e 50S ribosomal protein L44e PH1940 33 COG1631 RPL42A, Ribosomal protein L44E Translation, ribosomal structure and biogenesis 14590977 Common - X-Pro dipeptidase PH1149 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 14590742 Nonpathogen - hypothetical protein PH0885 2 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 14590970 Common - hypothetical protein PH1142 16 COG3463 COG3463, Predicted membrane protein Function unknown 14590314 Nonpathogen - hypothetical protein PH0407 4 COG1378 COG1378, Predicted transcriptional regulators Transcription 14590217 Nonpathogen - tRNA-splicing endonuclease subunit alpha PH0295 34 COG1676 SEN2, tRNA splicing endonuclease Translation, ribosomal structure and biogenesis 14591737 Nonpathogen ef1B elongation factor 1-beta PH0026b 18 COG2092 EFB1, Translation elongation factor EF-1beta Translation, ribosomal structure and biogenesis 14591061 Common truA tRNA pseudouridine synthase A PH1242 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 14591651 Common - inorganic pyrophosphatase PH1907 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 14590284 Common cobD cobalamin biosynthesis protein PH0376 147 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 14590082 Common - transcriptional regulator PH0140 176 COG1522 Lrp, Transcriptional regulators Transcription 14590195 Common - asparagine synthetase A PH0270 154 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 14590881 Common - hypothetical protein PH1044 106 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 14590074 Nonpathogen - hypothetical protein PH0130 2 None None None 14590139 Common - hypothetical protein PH0206 42 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 14591031 Common - phospho-sugar mutase PH1210 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 14590844 Nonpathogen - hypothetical protein PH1002 17 COG2248 COG2248, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 14590115 Nonpathogen - hypothetical protein PH0180 5 COG1777 COG1777, Predicted transcriptional regulators Transcription 14591158 Common - hypothetical protein PH1352 208 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 14590621 Common - hypothetical protein PH0751 25 COG1378 COG1378, Predicted transcriptional regulators Transcription 14590476 Nonpathogen - hypothetical protein PH0580 2 None None None 14591394 Common - hypothetical protein PH1619 23 COG1817 COG1817, Uncharacterized protein conserved in archaea Function unknown 14591696 Common - glucose-6-phosphate isomerase PH1956 18 COG2140 COG2140, Thermophilic glucose-6-phosphate isomerase and related metalloenzymes Carbohydrate transport and metabolism / General function prediction only 14590532 Common - hypothetical protein PH0642 205 COG0388 COG0388, Predicted amidohydrolase General function prediction only 14590140 Common - hypothetical protein PH0207 231 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 14590947 Common adk adenylate kinase PH1117 230 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 14589998 Nonpathogen - exosome complex RNA-binding protein Csl4 PH0043 23 COG1096 COG1096, Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) Translation, ribosomal structure and biogenesis 33359343 Nonpathogen - hypothetical protein PH0927.1n 1 None None None 14591226 Nonpathogen - hypothetical protein PH1433 4 None None None 14591670 Nonpathogen - hypothetical protein PH1927 4 None None None 14590955 Nonpathogen - hypothetical protein PH1127 22 COG1460 COG1460, Uncharacterized protein conserved in archaea Function unknown 14590309 Common - hypothetical protein PH0402 20 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 14590649 Common - alanine transport protein PH0781 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 14590394 Common - chemotaxis protein (cheY) PH0482 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 14590833 Common - hypothetical protein PH0988 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 14590855 Nonpathogen - hypothetical protein PH1015 22 COG1624 COG1624, Uncharacterized conserved protein Function unknown 14591006 Nonpathogen - hypothetical protein PH1181 2 None None None 14591086 Common - hypothetical protein PH1270 42 COG2510 COG2510, Predicted membrane protein Function unknown 33359295 Nonpathogen - hypothetical protein PH0466.1n 1 None None None 14591494 Common - ABC transporter ATP-binding protein PH1736 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 14590210 Nonpathogen - hypothetical protein PH0286 22 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 33359339 Nonpathogen - hypothetical protein PH0871.1n 1 None None None 14590130 Nonpathogen - DNA primase small subunit PH0195 31 COG1467 PRI1, Eukaryotic-type DNA primase, catalytic (small) subunit DNA replication, recombination, and repair 14590819 Common - dipeptidase PH0974 249 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 14590906 Nonpathogen - hypothetical protein PH1070 1 None None None 14589970 Common - hypothetical protein PH0008 39 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 14591151 Nonpathogen - hypothetical protein PH1344 2 COG4025 COG4025, Predicted membrane protein Function unknown 14591593 Common - ribokinase PH1845 204 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 14590545 Nonpathogen - hypothetical protein PH0660 31 COG1339 COG1339, Transcriptional regulator of a riboflavin/FAD biosynthetic operon Transcription / Coenzyme metabolism 14590764 Nonpathogen - hypothetical protein PHS028 1 None None None 14590581 Common - translation initiation factor IF-2B subunit beta PH0702 131 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 14590836 Common - periplasmic divalent cation tolerance protein CutA PH0992 121 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 14590942 Common - hypothetical protein PH1112 15 COG1430 COG1430, Uncharacterized conserved protein Function unknown 14590089 Nonpathogen - 2-phosphoglycerate kinase PH0149 14 COG2074 COG2074, 2-phosphoglycerate kinase Carbohydrate transport and metabolism 14590850 Nonpathogen - hypothetical protein PH1010 25 COG1931 COG1931, Uncharacterized protein conserved in archaea Function unknown 14590778 Common - mannose-1-phosphate guanylyl transferase PH0925 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 14590771 Common - hypothetical protein PH0917 83 COG1203 COG1203, Predicted helicases General function prediction only 14590593 Nonpathogen - hypothetical protein PH0715 1 None None None 14590796 Common - putative monovalent cation/H+ antiporter subunit G PH0944 55 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 14591484 Common leuD 3-isopropylmalate dehydratase small subunit PH1724 89 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 14590851 Common - tyrosyl-tRNA synthetase PH1011 51 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 14590135 Common - proteasome-activating nucleotidase PH0201 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 14590101 Nonpathogen - hypothetical protein PH0164 4 COG1421 COG1421, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 33359433 Common - hypothetical protein PH1856.1n 10 COG1522 Lrp, Transcriptional regulators Transcription 14590337 Nonpathogen - hypothetical protein PH0420 4 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 14591485 Common - 3-isopropylmalate dehydratase large subunit PH1726 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 14590642 Nonpathogen - hypothetical protein PH0773 1 None None None 14591074 Common - heat shock protein HtpX PH1256 192 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 14590136 Common - maltose/maltodextrin transport ATP-binding protein PH0203 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 14591210 Nonpathogen - hypothetical protein PH1414 2 COG3431 COG3431, Predicted membrane protein Function unknown 14591456 Nonpathogen - transcriptional regulator PHS045 9 COG1522 Lrp, Transcriptional regulators Transcription 14591476 Common - sugar transport ATP-binding protein PH1713 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 14591676 Common - hypothetical protein PH1934 65 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 14590829 Nonpathogen - hypothetical protein PH0984 9 COG4344 COG4344, Uncharacterized protein conserved in archaea Function unknown 14590099 Nonpathogen - hypothetical protein PH0161 7 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 14590306 Common - hypothetical protein PH0398 10 None None None 14590825 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A PH0980 79 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 14590196 Common - hypothetical protein PH0271 71 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 14590153 Nonpathogen - hypothetical protein PH0222 6 COG4697 COG4697, Uncharacterized protein conserved in archaea Function unknown 33359302 Nonpathogen - hypothetical protein PH0562 1 None None None 14590087 Nonpathogen - hypothetical protein PH0146 9 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 14590560 Common - pyruvate ferredoxin oxidoreductase subunit gamma PH0678 72 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 14590554 Nonpathogen - hypothetical protein PH0672 6 COG1800 COG1800, Predicted transglutaminase-like proteases General function prediction only 14590772 Nonpathogen - hypothetical protein PH0918 2 None None None 14591306 Nonpathogen - hypothetical protein PH1523 1 None None None 33359422 Nonpathogen - hypothetical protein PH1714.1n 2 None None None 33359403 Nonpathogen - hypothetical protein PH1422.1n 3 None None None 14590931 Nonpathogen - hypothetical protein PH1100 2 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 14590486 Nonpathogen - signal peptidase subunit PH0590 16 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 14590594 Nonpathogen - hypothetical protein PH0716 29 COG1992 COG1992, Uncharacterized conserved protein Function unknown 14591088 Nonpathogen - hypothetical protein PH1273 6 COG4072 COG4072, Uncharacterized protein conserved in archaea Function unknown 14591398 Common - hypothetical protein PH1623 41 COG1608 COG1608, Predicted archaeal kinase General function prediction only 14590496 Common - hypothetical protein PH0600 209 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 14591134 Common - alanine aminotransferase PH1322 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 161349992 Nonpathogen rpl15p 50S ribosomal protein L15P PH1755 18 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 14591596 Common - ATP-binding transport protein PH1849 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 14591528 Common rps3p 30S ribosomal protein S3P PH1772 240 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 14590659 Common - iron (III) dicitrate transport ATP-binding protein PH0791 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 14591203 Common - threonine synthase PH1406 183 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 14590815 Nonpathogen - hypothetical protein PH0970 1 None None None 14590946 Common - hypothetical protein PH1116 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 14591132 Common - hypothetical protein PH1320 248 COG1084 COG1084, Predicted GTPase General function prediction only 14591036 Common - hypothetical protein PH1216 150 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 14591247 Nonpathogen - hypothetical protein PH1457 1 None None None 14590783 Common - hypothetical protein PH0930 98 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 14590173 Common - hypothetical protein PH0242 24 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 14590838 Nonpathogen - hypothetical protein PH0995 8 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 14590147 Common - hypothetical protein PH0214 8 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 14591228 Common - hypothetical protein PH1435 54 COG3262 HycE, Ni,Fe-hydrogenase III component G Energy production and conversion 14591314 Common - ATP-binding transport protein PH1532 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 14590109 Nonpathogen - hypothetical protein PH0172 1 None None None 14590200 Nonpathogen - hypothetical protein PH0276 19 COG2117 COG2117, Predicted subunit of tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 14590459 Nonpathogen - hypothetical protein PH0560 2 COG3889 COG3889, Predicted solute binding protein General function prediction only 14591124 Nonpathogen - hypothetical protein PH1312 18 COG1885 COG1885, Uncharacterized protein conserved in archaea Function unknown 14591418 Common - hypothetical protein PH1648 15 COG4346 COG4346, Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase Posttranslational modification, protein turnover, chaperones 14591217 Nonpathogen - hypothetical protein PH1422 3 None None None 33359352 Nonpathogen - hypothetical protein PH0975.3n 1 None None None 14590075 Common - hypothetical protein PH0131 85 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 33359418 Common - 2-keto acid:ferredoxin oxidoreductase subunit delta PH1666.1n 56 COG1146 COG1146, Ferredoxin Energy production and conversion 14591752 Nonpathogen rpoK DNA-directed RNA polymerase subunit K PH1631a 30 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 14590491 Nonpathogen - hypothetical protein PH0595 1 None None None 14590326 Nonpathogen - hypothetical protein PHS016 4 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 14590544 Common pheS phenylalanyl-tRNA synthetase subunit alpha PH0658 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 14591064 Common - hypothetical protein PH1245 93 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 14590758 Common - hypothetical protein PH0902 36 COG1483 COG1483, Predicted ATPase (AAA+ superfamily) General function prediction only 14591355 Nonpathogen - hypothetical protein PH1577 8 COG2428 COG2428, Uncharacterized conserved protein Function unknown 14590627 Nonpathogen - hypothetical protein PH0757 15 COG3885 COG3885, Uncharacterized conserved protein Function unknown 14590358 Common - methyl-accepting chemotaxis protein PH0443 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 33359381 Nonpathogen - hypothetical protein PH1249 9 COG1688 COG1688, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 14590580 Nonpathogen - hypothetical protein PH0701 2 None None None 14591736 Nonpathogen - Predicted Zn-ribbon RNA-binding protein involved in translation PH0026a 30 COG2888 COG2888, Predicted Zn-ribbon RNA-binding protein with a function in translation Translation, ribosomal structure and biogenesis 14591274 Common - hypothetical protein PH1489 133 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 14590813 Nonpathogen - hypothetical protein PH0968 1 None None None 14590005 Nonpathogen - fibrillarin PH0052 34 COG1889 NOP1, Fibrillarin-like rRNA methylase Translation, ribosomal structure and biogenesis 14590288 Nonpathogen - hypothetical protein PH0379 7 None None None 14591262 Common - hypothetical protein PH1474 15 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 33359442 Nonpathogen - hypothetical protein PH1935 3 None None None 33359280 Nonpathogen - hypothetical protein PH0382 2 None None None 14591319 Common - nucleolar protein PH1537 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 33359317 Nonpathogen - hypothetical protein PH0687.2n 8 COG5260 TRF4, DNA polymerase sigma DNA replication, recombination, and repair 14590266 Common - hypothetical protein PH0356 73 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 14590600 Nonpathogen - hypothetical protein PH0723 1 None None None 14590504 Nonpathogen - hypothetical protein PH0611 15 COG1100 COG1100, GTPase SAR1 and related small G proteins General function prediction only 14590014 Common - hypothetical protein PH0061 98 COG1522 Lrp, Transcriptional regulators Transcription 14591575 Common - S-adenosylmethionine synthetase PH1824 43 COG1812 MetK, Archaeal S-adenosylmethionine synthetase Amino acid transport and metabolism 14590458 Nonpathogen - flagellar assembly protein J PH0559 20 COG1955 FlaJ, Archaeal flagella assembly protein J Cell motility and secretion / Intracellular trafficking and secretion 14590168 Nonpathogen - hypothetical protein PH0237 2 None None None 14590751 Common - hypothetical protein PH0894 18 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 14590929 Common - macrolide-efflux determinant PH1098 138 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 14590080 Common - hypothetical protein PH0137 18 COG3949 COG3949, Uncharacterized membrane protein Function unknown 14591323 Common - 30S ribosomal protein S7P PH1541 91 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 14590882 Common - hypothetical protein PH1045 23 COG1522 Lrp, Transcriptional regulators Transcription 14589997 Nonpathogen - hypothetical protein PH0042 2 COG3286 COG3286, Uncharacterized protein conserved in archaea Function unknown 14591269 Common rps10p 30S ribosomal protein S10P PH1483 245 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 14590875 Common - maltose transport inner membrane protein PH1036 191 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 14591413 Nonpathogen - hypothetical protein PH1643 1 None None None 161350000 Common - CTP synthetase PH1792 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 14591094 Nonpathogen - hypothetical protein PH1281 1 None None None 14590522 Nonpathogen - hypothetical protein PHS022 1 None None None 14590920 Common - aspartate kinase PH1086 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 14590802 Common - hypothetical protein PH0950 19 None None None 14591296 Nonpathogen - hypothetical protein PH1514 2 None None None 14591423 Common glyA serine hydroxymethyltransferase PH1654 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 14590481 Common - neutral protease PH0585 35 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 14590397 Common - hypothetical protein PH0487 42 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 14589967 Nonpathogen - hypothetical protein PH0005 2 None None None 14589978 Common - hypothetical protein PH0016 17 COG1892 COG1892, Uncharacterized protein conserved in archaea Function unknown 14590417 Common - hypothetical protein PH0515 28 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 14590589 Nonpathogen - hypothetical protein PH0711 12 COG2419 COG2419, Uncharacterized conserved protein Function unknown 14590890 Nonpathogen - hypothetical protein PH1053 1 None None None 14590971 Common - 5'-methylthioadenosine phosphorylase PH1143 168 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 14591004 Nonpathogen - hypothetical protein PH1179 2 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 14590319 Nonpathogen - hypothetical protein PHS010 1 None None None 14591699 Common - oligopeptide transport system permease protein appC PH1960 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 33359368 Common - hypothetical protein PH1160 41 COG0819 TenA, Putative transcription activator Transcription 14590351 Common - hypothetical protein PH0436 35 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14591438 Common - developmentally regulated GTP-binding protein PH1672 249 COG1163 DRG, Predicted GTPase General function prediction only 14591609 Nonpathogen - hypothetical protein PH1862 1 None None None 14590603 Common - ornithine carbamoyltransferase PH0726 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 14590059 Common - replication factor C large subunit PH0113 210 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 14591350 Common - protease IV PH1569 153 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 14591028 Nonpathogen - hypothetical protein PH1207 1 None None None 14590229 Common - pyrolysin PH0310 8 COG4870 COG4870, Cysteine protease Posttranslational modification, protein turnover, chaperones 14590028 Common - hypothetical protein PH0074 22 COG1432 COG1432, Uncharacterized conserved protein Function unknown 14591629 Common - triosephosphate isomerase PH1884 38 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 14590629 Common - hypothetical protein PH0759 37 COG1980 COG1980, Archaeal fructose 1,6-bisphosphatase Carbohydrate transport and metabolism 14590356 Nonpathogen - hypothetical protein PH0441 1 None None None 14590057 Common - hypothetical protein PH0109 69 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 14590707 Common - hypothetical protein PH0846 32 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 33359257 Nonpathogen - hypothetical protein PH0097.2n 1 None None None 14590668 Common - reverse gyrase PH0800 234 COG1110 COG1110, Reverse gyrase DNA replication, recombination, and repair 14591587 Nonpathogen - hypothetical protein PH1838 1 None None None 33359372 Nonpathogen - hypothetical protein PH1192.1n 2 None None None 14590371 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase PH0460 46 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 14590261 Nonpathogen - hypothetical protein PH0350 21 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 14591465 Nonpathogen - archaeal histon PHS046 20 COG2036 HHT1, Histones H3 and H4 Chromatin structure and dynamics 14591321 Nonpathogen - peptidyl-tRNA hydrolase PH1539 34 COG1990 COG1990, Uncharacterized conserved protein Function unknown 14590395 Common - chemotaxis-specific methylesterase PH0483 220 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 14591267 Nonpathogen - ribonuclease P protein component 2 PH1481 20 COG1369 POP5, RNase P/RNase MRP subunit POP5 Translation, ribosomal structure and biogenesis 14590033 Common - hypothetical protein PH0080 27 COG1818 COG1818, Predicted RNA-binding protein, contains THUMP domain General function prediction only 14591614 Common - hypothetical protein PH1867 63 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 14591153 Common - GMP synthase subunit A PH1346 241 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 14590905 Nonpathogen - hypothetical protein PH1069 16 COG1590 COG1590, Uncharacterized conserved protein Function unknown 161350002 Common rpl14p 50S ribosomal protein L14P PH1768 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 14591400 Common - hypothetical protein PH1626 69 COG1355 COG1355, Predicted dioxygenase General function prediction only 14590249 Nonpathogen - hypothetical protein PH0334 1 None None None 14591535 Common rpl3p 50S ribosomal protein L3P PH1777 110 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 14590470 Common - NADH oxidase PH0572 242 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 33359264 Nonpathogen - DNA primase large subunit PH0196 6 COG2219 PRI2, Eukaryotic-type DNA primase, large subunit DNA replication, recombination, and repair 14591686 Common - hypothetical protein PH1945 25 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 14591701 Common - hypothetical protein PH1962 15 COG3889 COG3889, Predicted solute binding protein General function prediction only 14590127 Nonpathogen - hypothetical protein PH0192 1 None None None 14590696 Nonpathogen - hypothetical protein PH0829 1 None None None 14591694 Nonpathogen - hypothetical protein PH1954 1 None None None 14590061 Nonpathogen - hypothetical protein PH0115 35 COG2520 COG2520, Predicted methyltransferase General function prediction only 14591379 Common - hypothetical protein PH1602 117 COG1690 RtcB, Uncharacterized conserved protein Function unknown 14590640 Common - aspartate aminotransferase PH0771 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 14591367 Common - deoxycytidylate deaminase PH1589 97 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 14591757 Nonpathogen - DNA-directed RNA polymerase subunit E'' PH1908a 34 COG2093 COG2093, DNA-directed RNA polymerase, subunit E'' Transcription 33359375 Nonpathogen - hypothetical protein PH1205.1n 20 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 14590542 Common tdh L-threonine 3-dehydrogenase PH0655 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 14590992 Common - hypothetical protein PH1166 27 COG1625 COG1625, Fe-S oxidoreductase, related to NifB/MoaA family Energy production and conversion 14590324 Nonpathogen - hypothetical protein PHS015 1 None None None 14591057 Common - hypothetical protein PH1238 39 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 14590433 Nonpathogen - prefoldin subunit beta PH0532 32 COG1382 GimC, Prefoldin, chaperonin cofactor Posttranslational modification, protein turnover, chaperones 14590767 Common - resistance ATP-binding protein PH0913 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 14591553 Common - chromosome assembly protein PH1798 193 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 14591089 Common - formaldehyde:ferredoxin oxidoreductase PH1274 59 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 33359383 Common - hypothetical protein PH1263.1n 20 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14590508 Nonpathogen - 30S ribosomal protein S6e PH0615 34 COG2125 RPS6A, Ribosomal protein S6E (S10) Translation, ribosomal structure and biogenesis 33359354 Nonpathogen - putative molybdopterin converting factor, subunit 1 PH1017.1n 22 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 14590848 Nonpathogen - hypothetical protein PH1008 37 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 14590619 Common - hypothetical protein PH0746 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 14591175 Common - sodium-dependent transporter PH1372 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 14590562 Common vorA 2-ketoisovalerate ferredoxin oxidoreductase subunit alpha PH0680 137 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 33359332 Common - hypothetical protein PH0799 28 COG1378 COG1378, Predicted transcriptional regulators Transcription 14590046 Common - purine phosphoribosyltransferase PH0095 118 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 33359252 Nonpathogen - hypothetical protein PH0066.1n 2 None None None 14591082 Nonpathogen rpl34e 50S ribosomal protein L34e PHS035 16 COG2174 RPL34A, Ribosomal protein L34E Translation, ribosomal structure and biogenesis 33359297 Nonpathogen - hypothetical protein PH0472 2 COG1997 RPL43A, Ribosomal protein L37AE/L43A Translation, ribosomal structure and biogenesis 33359395 Nonpathogen - hypothetical protein PH1355.1n 3 COG4031 COG4031, Predicted metal-binding protein General function prediction only 14591428 Common - hypothetical protein PH1659 181 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 14590743 Nonpathogen - hypothetical protein PH0886 8 COG0730 COG0730, Predicted permeases General function prediction only 14590980 Common - hypothetical protein PH1152 38 COG1916 COG1916, Uncharacterized homolog of PrgY (pheromone shutdown protein) Function unknown 14590436 Nonpathogen - hypothetical protein PH0535 2 None None None 14591047 Common - hypothetical protein PH1228 31 COG1907 COG1907, Predicted archaeal sugar kinases General function prediction only 14590932 Nonpathogen - hypothetical protein PH1101 2 COG4742 COG4742, Predicted transcriptional regulator Transcription 14591122 Nonpathogen - hypothetical protein PH1311 17 COG1475 Spo0J, Predicted transcriptional regulators Transcription 14591215 Nonpathogen - hypothetical protein PH1420 5 COG1689 COG1689, Uncharacterized protein conserved in archaea Function unknown 14589989 Common - aldehyde:ferredoxin oxidoreductase PH0028 59 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 14590682 Nonpathogen - hypothetical protein PH0815 1 None None None 14590445 Nonpathogen - hypothetical protein PH0544 7 COG3373 COG3373, Uncharacterized protein conserved in archaea Function unknown 14591401 Common - threonine synthase PH1627 206 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 14590902 Common - DNA repair protein RAD25 PH1064 92 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 14591501 Common - hypothetical protein PH1743 111 COG0546 Gph, Predicted phosphatases General function prediction only 14591441 Common - hypothetical protein PH1675 26 COG3199 COG3199, Uncharacterized conserved protein Function unknown 14590989 Common - hypothetical protein PH1162 135 COG2252 COG2252, Permeases General function prediction only 14591336 Nonpathogen - proteasome subunit alpha PH1553 34 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 14591715 Common - V-type ATP synthase subunit E PH1978 33 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 14591595 Common - hypothetical protein PH1848 37 COG1511 COG1511, Predicted membrane protein Function unknown 14591668 Nonpathogen - hypothetical protein PH1924 1 None None None 14590538 Nonpathogen - hypothetical protein PH0649 2 None None None 14590367 Common - hypothetical protein PH0456 215 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 14590969 Nonpathogen - hypothetical protein PH1141 1 COG5427 COG5427, Uncharacterized membrane protein Function unknown 14590730 Nonpathogen - hypothetical protein PH0871 1 None None None 14590962 Common - hypothetical protein PH1134 117 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 14591113 Nonpathogen - hypothetical protein PH1303 1 None None None 14591235 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase PH1444 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 14591301 Nonpathogen - small nuclear ribonucleoprotein PHS042 32 COG1958 LSM1, Small nuclear ribonucleoprotein (snRNP) homolog Transcription 14590360 Nonpathogen - hypothetical protein PH0446 5 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 14590940 Common - hypothetical protein PH1109 161 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 14590521 Common - neutral protease PH0630 35 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 14590345 Common - Vi polysaccharide biosynthesis protein PH0429 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 14590219 Nonpathogen - hypothetical protein PHS005 2 None None None 14591349 Nonpathogen - translation initiation factor IF-1A PH1568 34 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 14591649 Common - hypothetical protein PH1904 49 COG0011 COG0011, Uncharacterized conserved protein Function unknown 14590739 Common - ABC transporter ATP-binding protein PH0882 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 14591435 Nonpathogen - hypothetical protein PH1668 1 None None None 33359428 Nonpathogen - hypothetical protein PH1794 2 None None None 14591521 Common rpl5p 50S ribosomal protein L5P PH1765 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 14591107 Nonpathogen - hypothetical protein PH1297 9 COG1895 COG1895, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 14589982 Common - anaerobic ribonucleoside triphosphate reductase PH0021 84 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 14590253 Common - hypothetical protein PH0338 40 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 14590085 Nonpathogen - hypothetical beta-lactamase PH0143 5 None None None 14591721 Common - preprotein translocase subunit SecF PH1986 150 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 14591286 Common ccrB camphor resistance protein CrcB PH1502 61 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 14591624 Nonpathogen - ribonuclease P protein component 3 PH1877 11 COG1603 RPP1, RNase P/RNase MRP subunit p30 Translation, ribosomal structure and biogenesis 14591240 Common - NADH-ubiquinone oxidoreductase subunit PH1450 187 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 14591576 Common - integrase/recombinase PH1826 231 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 14591508 Common - sarcosine oxidase PH1751 155 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 14591631 Common pcm protein-L-isoaspartate O-methyltransferase PH1886 167 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 14590118 Nonpathogen - hypothetical protein PH0183 3 None None None 14591380 Common - hypothetical protein PH1605 60 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 14591258 Nonpathogen - hypothetical protein PH1470 30 COG1701 COG1701, Uncharacterized protein conserved in archaea Function unknown 14590862 Nonpathogen - hypothetical protein PH1023 2 None None None 14590899 Nonpathogen - hypothetical protein PH1062 1 None None None 14590016 Common - hypothetical protein PH0062 59 COG0640 ArsR, Predicted transcriptional regulators Transcription 14591017 Nonpathogen - hypothetical protein PH1192 2 None None None 14591012 Nonpathogen - hypothetical protein PH1187 1 None None None 14590298 Common - hypothetical protein PH0390 117 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 14591602 Nonpathogen - hypothetical protein PH1856 32 COG1602 COG1602, Uncharacterized conserved protein Function unknown 14590237 Common - phosphoribosylaminoimidazole carboxylase catalytic subunit PH0320 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 14590167 Nonpathogen - hypothetical protein PH0236 22 COG3273 COG3273, Uncharacterized conserved protein Function unknown 14591728 Common - glycine dehydrogenase subunit 2 PH1994 175 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 33359421 Nonpathogen - hypothetical protein PH1686.1n 1 None None None 14590111 Common - hypothetical protein PH0175 32 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 14590639 Nonpathogen - hypothetical protein PH0770 2 COG1617 COG1617, Uncharacterized conserved protein Function unknown 14590713 Common - adenylosuccinate lyase PH0852 241 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 14590498 Nonpathogen - hypothetical protein PH0602 1 None None None 14591246 Common - putative monovalent cation/H+ antiporter subunit E PH1456 72 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 14590877 Common - hypothetical protein PH1039 84 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 14590884 Common - hypothetical protein PH1047 8 COG1297 COG1297, Predicted membrane protein Function unknown 161349999 Common - ferredoxin--NADP(+) reductase subunit alpha PH1874 69 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 14590944 Common - hypothetical protein PH1114 43 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 14590468 Nonpathogen - hypothetical protein PH0569 2 None None None 14591598 Common - methyl-accepting chemotaxis protein PH1852 154 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 14591205 Common - hypothetical protein PH1409 198 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 14590263 Common - hypothetical protein PH0353 37 COG1786 COG1786, Uncharacterized conserved protein Function unknown 14590596 Nonpathogen - hypothetical protein PH0719 1 None None None 14590202 Nonpathogen - hypothetical protein PH0278 1 None None None 14591446 Common - hypothetical protein PH1682 88 COG0393 COG0393, Uncharacterized conserved protein Function unknown 14590817 Nonpathogen - hypothetical protein PH0972 2 None None None 14590807 Nonpathogen - hypothetical protein PH0955 1 None None None 14591754 Common SUI1 translation initiation factor Sui1 PH1771a 54 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 14590810 Nonpathogen - hypothetical protein PH0962 33 COG1258 COG1258, Predicted pseudouridylate synthase Translation, ribosomal structure and biogenesis 14591658 Common - leucine-responsive regulatory protein PH1916 173 COG1522 Lrp, Transcriptional regulators Transcription 14590091 Common - hypothetical protein PH0152 48 COG1801 COG1801, Uncharacterized conserved protein Function unknown 14591517 Nonpathogen rpl32e 50S ribosomal protein L32e PH1761 34 COG1717 RPL32, Ribosomal protein L32E Translation, ribosomal structure and biogenesis 14591406 Common rpl13p 50S ribosomal protein L13P PH1634 167 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 14591312 Common - hypothetical protein PH1530 53 COG0622 COG0622, Predicted phosphoesterase General function prediction only 14591482 Common - ribosomal protein S6 modification protein PH1721 101 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 14590145 Nonpathogen - hypothetical protein PH0212 4 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 14590515 Nonpathogen - phosphopantetheine adenylyltransferase PH0624 28 COG1019 COG1019, Predicted nucleotidyltransferase General function prediction only 14590077 Nonpathogen - hypothetical protein PH0134 31 COG1340 COG1340, Uncharacterized archaeal coiled-coil protein Function unknown 14590191 Common - succinyl-diaminopimelate desuccinylase PH0265 213 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 14591462 Common - DNA primase PH1699 39 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 33359313 Nonpathogen - hypothetical protein PH0664.1n 2 None None None 14591009 Nonpathogen - hypothetical protein PH1184 1 None None None 14591674 Common - hypothetical protein PH1932 14 COG4742 COG4742, Predicted transcriptional regulator Transcription 14590965 Common - RNA methyltransferase PH1137 207 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 14590159 Nonpathogen - hypothetical protein PH0228 7 COG2441 COG2441, Predicted butyrate kinase Energy production and conversion 33359431 Nonpathogen - hypothetical protein PH1827.1n 1 None None None 14591002 Nonpathogen - hypothetical protein PH1177 2 COG1711 COG1711, Uncharacterized protein conserved in archaea Function unknown 14591611 Nonpathogen - hypothetical protein PH1864 7 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 33359438 Nonpathogen - hypothetical protein PH1893.1n 2 None None None 14590552 Common - aspartate racemase PH0670 92 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 14590853 Common - hypothetical protein PH1013 78 COG1522 Lrp, Transcriptional regulators Transcription 14591497 Common - hypothetical protein PH1739 144 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 14590827 Common - hypothetical protein PH0982 35 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 33359397 Nonpathogen - hypothetical protein PH1359.1n 9 None None None 14591076 Common - hypothetical protein PH1257 46 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 14590832 Common - hypothetical protein PH0987 115 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 14591266 Nonpathogen - hypothetical protein PH1479 34 COG1537 PelA, Predicted RNA-binding proteins General function prediction only 14590839 Nonpathogen - hypothetical protein PH0996 1 None None None 14590405 Common - hypothetical protein PH0499 73 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 33359269 Nonpathogen - hypothetical protein PH0281 5 COG1374 NIP7, Protein involved in ribosomal biogenesis, contains PUA domain Translation, ribosomal structure and biogenesis 14590273 Common - galactose-1-phosphate uridyltransferase PH0365 78 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 33359315 Common - frxA protein PH0674 5 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 14591454 Common - transcriptional regulator PH1692 146 COG1522 Lrp, Transcriptional regulators Transcription 14591628 Common - glucose-fructose oxidoreductase PH1882 184 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 14590502 Common - cell division control protein PH0606 40 COG1241 MCM2, Predicted ATPase involved in replication control, Cdc46/Mcm family DNA replication, recombination, and repair 14591496 Nonpathogen - hypothetical protein PH1738 2 None None None 14591544 Common - hypothetical protein PH1786 95 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 14591298 Common - dihydroorotate dehydrogenase 1B PH1516 239 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 14589976 Nonpathogen - hypothetical protein PH0014 12 COG1906 COG1906, Uncharacterized conserved protein Function unknown 14589969 Nonpathogen - hypothetical protein PH0007 12 COG2413 COG2413, Predicted nucleotidyltransferase General function prediction only 14590310 Nonpathogen - hypothetical protein PH0403 11 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 33359405 Common - hypothetical protein PH1454.1n 27 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 14590710 Common - hypothetical protein PH0849 166 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 14591325 Common nusA transcription elongation factor NusA-like protein PH1543 36 COG0195 NusA, Transcription elongation factor Transcription 14590161 Common - hypothetical protein PH0230 68 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 33359267 Common - hypothetical protein PH0260 80 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 14591633 Nonpathogen - hypothetical protein PH1888 26 COG1244 COG1244, Predicted Fe-S oxidoreductase General function prediction only 14589973 Common - nicotinate-nucleotide pyrophosphorylase PH0011 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 14590373 Nonpathogen - hypothetical protein PH0462 2 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 14591050 Nonpathogen - hypothetical protein PH1231 4 COG3368 COG3368, Predicted permease General function prediction only 14590922 Common - aspartate-semialdehyde dehydrogenase PH1088 188 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 14590577 Common ndk nucleoside diphosphate kinase PH0698 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 33359417 Nonpathogen - hypothetical protein PH1600.1n 2 None None None 14590304 Common - hypothetical protein PH0396 185 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 14591510 Nonpathogen - adenylate kinase PH1753 24 COG2019 AdkA, Archaeal adenylate kinase Nucleotide transport and metabolism 14591697 Common - oligopeptide transport ATP-binding protein appF PH1958 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 14590537 Nonpathogen - hypothetical protein PH0648 2 COG1627 COG1627, Uncharacterized protein conserved in archaea Function unknown 14590774 Nonpathogen - hypothetical protein PH0920 16 COG1857 COG1857, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 14590209 Common - methionyl-tRNA synthetase PH0285 119 COG0073 ARC1, EMAP domain General function prediction only 14590761 Nonpathogen - hypothetical protein PH0908 1 None None None 14590399 Common - hypothetical protein PH0490 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 33359361 Common - hypothetical protein PH1105.1n 33 COG3269 COG3269, Predicted RNA-binding protein, contains TRAM domain General function prediction only 14590390 Common - purine-binding chemotaxis protein (cheW) PH0478 127 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 14591573 Nonpathogen - hypothetical protein PH1822 33 COG1491 COG1491, Predicted RNA-binding protein Translation, ribosomal structure and biogenesis 14591180 Nonpathogen - hypothetical protein PH1377 4 None None None 14590897 Nonpathogen - hypothetical protein PH1060 30 COG2118 COG2118, DNA-binding protein General function prediction only 14590112 Common - hypothetical protein PH0176 110 COG1203 COG1203, Predicted helicases General function prediction only 14590175 Nonpathogen - hypothetical protein PH0244 5 None None None 14590800 Nonpathogen - hypothetical protein PH0948 2 COG4933 COG4933, Uncharacterized conserved protein Function unknown 14591070 Nonpathogen - hypothetical protein PH1252 24 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 14591096 Common - methylmalonyl-CoA decarboxylase beta chain PH1283 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 14590777 Common - phospho-sugar mutase PH0923 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 14591713 Nonpathogen - V-type ATP synthase subunit F PH1976 11 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 14590997 Common - endo-1,4-beta-glucanase PH1171 18 COG2730 BglC, Endoglucanase Carbohydrate transport and metabolism 33359437 Nonpathogen - hypothetical protein PH1878 2 None None None 14591177 Common - proliferating-cell nucleolar protein p120 PH1374 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 14591360 Common - dipeptide transport protein dppA PH1582 35 COG2362 DppA, D-aminopeptidase Amino acid transport and metabolism 14590281 Common cobS cobalamin synthase PH0373 120 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 33359344 Nonpathogen - hypothetical protein PH0928 4 COG1630 COG1630, Uncharacterized protein conserved in archaea Function unknown 14591272 Common - lipoate protein ligase PH1487 98 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 14591130 Common - hypothetical protein PH1318 17 COG5423 COG5423, Predicted metal-binding protein Function unknown 14591415 Nonpathogen - ADP-specific phosphofructokinase PH1645 8 COG4809 COG4809, Archaeal ADP-dependent phosphofructokinase/glucokinase Carbohydrate transport and metabolism 14590003 Common - hypothetical protein PH0048 11 COG2234 Iap, Predicted aminopeptidases General function prediction only 14590410 Common - oligopeptide transport system permease protein AppC PH0504 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 14591459 Common - hypothetical protein PH1696 21 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 14590666 Nonpathogen - hypothetical protein PH0798 1 None None None 14590870 Common - modification methylase (adenine-specific) PH1032 99 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 14591260 Common - hypothetical protein PH1472 155 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 14591471 Nonpathogen - hypothetical protein PH1708 2 None None None 161350007 Common thiE thiamine-phosphate pyrophosphorylase PH1156 208 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 14591759 Nonpathogen - 30S ribosomal protein S27ae PH1910a 28 COG1998 RPS31, Ribosomal protein S27AE Translation, ribosomal structure and biogenesis 14591690 Nonpathogen - hypothetical protein PH1949 18 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 14590268 Nonpathogen - hypothetical protein PH0358 9 COG2083 COG2083, Uncharacterized protein conserved in archaea Function unknown 14590348 Common - hypothetical protein PH0433 158 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 14591382 Common - PHNP protein PH1607 73 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 33359282 Nonpathogen - hypothetical protein PH0403.1n 2 COG5559 COG5559, Uncharacterized conserved small protein Function unknown 14591429 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit gamma PH1660 69 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 14591692 Common - hypothetical protein PH1952 119 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 14591234 Nonpathogen - hypothetical protein PH1443 1 None None None 14591191 Common - hypothetical protein PH1389 46 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 14590540 Common - hypothetical protein PH0653 70 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 14590487 Nonpathogen - hypothetical protein PH0591 9 COG1772 COG1772, Uncharacterized protein conserved in archaea Function unknown 14591566 Common - TRK system potassium uptake protein PH1813 141 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 14590690 Common - hypothetical protein PH0823 56 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 14591284 Common - endonuclease III PH1498 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 33359279 Nonpathogen - hypothetical protein PH0381.2n 1 None None None 14590251 Common - hypothetical protein PH0336 231 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 14591688 Common - DNA-directed DNA polymerase PH1947 69 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 33359304 Nonpathogen - hypothetical protein PH0568 16 COG1633 COG1633, Uncharacterized conserved protein Function unknown 14590052 Nonpathogen - hypothetical protein PH0102 10 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 14590753 Common - transcriptional regulatory protein hypF PH0897 122 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 14590247 Nonpathogen - hypothetical protein PH0332 1 None None None 14590001 Nonpathogen - hypothetical protein PH0046 4 COG5625 COG5625, Predicted transcription regulator containing HTH domain Transcription 14591460 Common - mannose-1-phosphate guanyltransferase PH1697 238 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 14590244 Nonpathogen - hypothetical protein PH0328 1 None None None 14591331 Nonpathogen - hypothetical protein PH1547 2 None None None 33359299 Nonpathogen - hypothetical protein PH0517 2 None None None 14590044 Common - hypothetical protein PH0093 44 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 14590125 Nonpathogen - hypothetical protein PH0190 2 None None None 14590994 Nonpathogen - hypothetical protein PH1168 1 None None None 14591059 Nonpathogen - hypothetical protein PH1240 4 COG3270 COG3270, Uncharacterized conserved protein Function unknown 14590387 Nonpathogen - hypothetical protein PH0475 1 None None None 14590912 Nonpathogen - hypothetical protein PH1077 1 None None None 33359370 Nonpathogen - hypothetical protein PH1175.2n 1 None None None 14591555 Common - hypothetical protein PH1802 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 14590322 Common - hypothetical protein PHS013 8 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 14590549 Nonpathogen - DNA polymerase sliding clamp PH0665 34 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 14591181 Nonpathogen - hypothetical protein PH1378 4 COG1409 Icc, Predicted phosphohydrolases General function prediction only 14590973 Nonpathogen - hypothetical protein PH1145 2 None None None 14590506 Common - hypothetical protein PH0613 50 COG2510 COG2510, Predicted membrane protein Function unknown 33359356 Nonpathogen - hypothetical protein PH1028.2n 1 None None None 14590181 Nonpathogen - hypothetical protein PH0252 1 None None None 14591278 Nonpathogen - hypothetical protein PH1493 2 None None None 33359250 Nonpathogen - hypothetical protein PH0065.1n 1 None None None 14591118 Nonpathogen - hypothetical protein PH1307 17 COG2112 COG2112, Predicted Ser/Thr protein kinase Signal transduction mechanisms 14590220 Common alaS alanyl-tRNA synthetase PH0297 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 33359388 Nonpathogen - hypothetical protein PH1295.3n 3 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 161350009 Nonpathogen - 50S ribosomal protein L15e PH0978 34 COG1632 RPL15A, Ribosomal protein L15E Translation, ribosomal structure and biogenesis 14591372 Common - Na(+)/H(+) antiporter PH1594 101 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 14591365 Common - hypothetical protein PH1587 8 COG3682 COG3682, Predicted transcriptional regulator Transcription 18656946 Nonpathogen rpl14E 50S ribosomal protein L14e PH1265a 19 COG2163 RPL14A, Ribosomal protein L14E/L6E/L27E Translation, ribosomal structure and biogenesis 14590030 Nonpathogen - hypothetical protein PH0076 5 COG2874 FlaH, Predicted ATPases involved in biogenesis of archaeal flagella Cell motility and secretion / Intracellular trafficking and secretion 14590634 Common - indolepyruvate ferredoxin oxidoreductase alpha subunit PH0765 109 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 14589987 Common - hypothetical protein PH0026 5 None None None 14591026 Nonpathogen - hypothetical protein PH1204 1 None None None 14590705 Common - hypothetical protein PH0844 24 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14590424 Nonpathogen - hypothetical protein PH0522 2 None None None 33359259 Nonpathogen - hypothetical protein PH0144.3n 2 None None None 14590605 Common - hypothetical protein PH0728 18 COG1568 COG1568, Predicted methyltransferases General function prediction only 33359248 Nonpathogen - hypothetical anaerobic ribonucleoside-triphosphate reductase PH0027.1n 2 None None None 14590951 Nonpathogen - hypothetical protein PH1122 2 None None None 33359415 Common - hypothetical protein PH1586 9 COG2456 COG2456, Uncharacterized conserved protein Function unknown 14591052 Nonpathogen - hypothetical protein PH1233 2 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 14591718 Nonpathogen - V-type ATP synthase subunit H PH1983 2 None None None 14591000 Common - hypothetical protein PH1174 139 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 14590510 Nonpathogen - hypothetical protein PH0618 9 COG4044 COG4044, Uncharacterized protein conserved in archaea Function unknown 14590613 Common - hypothetical protein PH0738 45 COG1656 COG1656, Uncharacterized conserved protein Function unknown 14591467 Nonpathogen - hypothetical protein PH1703 1 None None None 14590207 Nonpathogen - hypothetical protein PH0283 13 COG1318 COG1318, Predicted transcriptional regulators Transcription 33359270 Nonpathogen - hypothetical protein PH0316.1n 1 None None None 14590431 Nonpathogen - hypothetical protein PH0530 8 COG1475 Spo0J, Predicted transcriptional regulators Transcription 14591038 Common pgk phosphoglycerate kinase PH1218 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 14591585 Nonpathogen - hypothetical protein PH1836 4 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 14590255 Common - hypothetical protein PH0343 36 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 33359255 Nonpathogen - hypothetical protein PH0096.1n 1 None None None 14590610 Common - hypothetical protein PH0735 157 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 14590227 Common - inositol-5-monophosphate dehydrogenase PH0307 244 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 14591007 Nonpathogen - hypothetical protein PH1182 2 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 14590176 Common - proteasome beta subunit PH0245 36 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 14590083 Nonpathogen - hypothetical protein PH0141 1 None None None 14591105 Nonpathogen - hypothetical protein PHS036 2 None None None 14591077 Common - hypothetical protein PH1259 201 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 33359341 Nonpathogen - hypothetical protein PHS027.1n 4 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 14590550 Nonpathogen - hypothetical protein PH0666 2 COG1711 COG1711, Uncharacterized protein conserved in archaea Function unknown 14590239 Nonpathogen - hypothetical protein PH0322 2 None None None 14591242 Common - NADH dehydrogenase subunit N PH1452 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 14591256 Common - hypothetical protein PH1468 107 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 14590729 Nonpathogen - hypothetical protein PH0870 13 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 14590860 Common aspC aspartyl-tRNA synthetase PH1020 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 14590650 Common - 4-aminobutyrate aminotransferase PH0782 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 14591143 Common - cell division protein FtsZ PH1335 205 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 14591010 Nonpathogen - hypothetical protein PH1185 1 None None None 14589980 Nonpathogen - hypothetical protein PH0019 1 None None None 14590528 Common - regulatory protein AsnC PHS023 44 COG1522 Lrp, Transcriptional regulators Transcription 14590676 Common - oligopeptide transport permease protein APPC PH0809 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 33359367 Nonpathogen - hypothetical protein PH1152.2n 2 None None None 14591546 Common - hypothetical protein PH1788 135 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 14591642 Common - elongation factor EF-2 PH1899 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 14590749 Common - aldehyde:ferredoxin oxidoreductase PH0892 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 14590230 Common - hypothetical protein PH0311 155 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 33359329 Nonpathogen - hypothetical protein PH0786.1n 1 None None None 14590582 Common - hypothetical protein PH0703 25 COG1824 COG1824, Permease, similar to cation transporters Inorganic ion transport and metabolism 14591354 Common - hypothetical protein PH1575 40 COG1578 COG1578, Uncharacterized conserved protein Function unknown 14591084 Common - hypothetical protein PH1267 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 14590579 Common - hypothetical protein PH0700 20 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 14591344 Nonpathogen - hypothetical protein PH1562 4 COG1771 COG1771, Uncharacterized protein conserved in archaea Function unknown 14590925 Common - hypothetical protein PH1091 44 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 14591726 Common - S-adenosylmethionine decarboxylase proenzyme PH1992 74 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 14590093 Common - transport system protein PH0154 229 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 14591129 Common - glycine cleavage system protein H PH1317 186 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 161350010 Common - glyoxylate reductase PH0597 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 14590741 Common - malic acid transport protein PH0884 71 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 14590720 Nonpathogen - hypothetical protein PH0860 2 None None None 14591170 Common - hypothetical protein PH1365 56 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 33359330 Nonpathogen - hypothetical protein PH0786.2n 1 None None None 14589991 Common - hypothetical protein PH0032 110 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 14590335 Common - dTDP-4-dehydrorhamnose reductase PH0417 186 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 33359286 Nonpathogen - hypothetical protein PHS010.5n 3 None None None 14590982 Common - phosphomethylpyrimidine kinase PH1155 223 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 14590443 Nonpathogen - hypothetical protein PH0542 2 COG5096 COG5096, Vesicle coat complex, various subunits Intracellular trafficking and secretion 14591448 Common - fumarate hydratase PH1684 141 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 14591166 Nonpathogen - hypothetical protein PH1360 2 None None None 14590275 Common - hypothetical protein PH0367 165 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 14590564 Common porD pyuvate ferredoxin oxidoreductase subunit delta PH0682 77 COG1144 COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit Energy production and conversion 14590900 Nonpathogen - hypothetical protein PHS031 3 COG1753 COG1753, Uncharacterized conserved protein Function unknown 14590293 Nonpathogen - hypothetical protein PH0384 9 None None None 14590008 Nonpathogen - hypothetical protein PH0055 1 None None None 14590559 Common - hypothetical protein PH0677 192 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 14590366 Common - ATP-dependent protease La PH0452 204 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 14590376 Nonpathogen nusA transcription elongation factor NusA PHS019 2 COG0195 NusA, Transcription elongation factor Transcription 14590442 Nonpathogen - hypothetical protein PH0541 2 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14590967 Common - hypothetical protein PH1139 108 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 14591244 Common - putative monovalent cation/H+ antiporter subunit B PH1454 26 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 33359320 Nonpathogen - hypothetical protein PH0697.1n 2 None None None 14590960 Common - sodium dependent phosphate transporter PH1131 141 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 14591040 Nonpathogen - hypothetical protein PH1221 4 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 14591024 Nonpathogen - hypothetical protein PH1201 1 None None None 14590791 Common rbcL ribulose bisophosphate carboxylase PH0939 68 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 33359262 Common - hypothetical protein PH0173.1n 23 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 14590809 Common - translation initiation factor IF-2 subunit alpha PH0961 181 COG1093 SUI2, Translation initiation factor 2, alpha subunit (eIF-2alpha) Translation, ribosomal structure and biogenesis 14591111 Nonpathogen - hypothetical protein PH1301 1 None None None 14591724 Common - hypothetical protein PH1989 47 COG0392 COG0392, Predicted integral membrane protein Function unknown 14590737 Nonpathogen - hypothetical protein PH0880 6 COG1433 COG1433, Uncharacterized conserved protein Function unknown 14591746 Nonpathogen - H/ACA RNA-protein complex component Nop10p PH0959a 24 COG2260 COG2260, Predicted Zn-ribbon RNA-binding protein Translation, ribosomal structure and biogenesis 14591666 Nonpathogen - hypothetical protein PH1922 5 COG4933 COG4933, Uncharacterized conserved protein Function unknown 14590548 Nonpathogen - DNA-directed RNA polymerase subunit M PH0664 33 COG1594 RPB9, DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS Transcription 33359435 Nonpathogen - hypothetical protein PH1869.1n 1 None None None 14591172 Common - hypothetical protein PH1368 18 COG1470 COG1470, Predicted membrane protein Function unknown 14591144 Nonpathogen - hypothetical protein PH1337 2 None None None 14591072 Nonpathogen - hypothetical protein PH1254 1 None None None 14591098 Nonpathogen - hypothetical protein PH1285 2 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 14590978 Common - arylmalonate decarboxylase PH1150 48 COG3473 COG3473, Maleate cis-trans isomerase Secondary metabolites biosynthesis, transport, and catabolism 14590401 Nonpathogen - hypothetical protein PH0493 2 None None None 14590511 Nonpathogen - transcription initiation factor E subunit alpha PH0619 30 COG1675 TFA1, Transcription initiation factor IIE, alpha subunit Transcription 14590283 Common - hypothetical protein PH0375 50 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 14591277 Nonpathogen - hypothetical protein PH1492 2 None None None 14590788 Common - hypothetical protein PH0936 24 COG0170 SEC59, Dolichol kinase Lipid metabolism 14591571 Nonpathogen - archaemetzincin-like protein PH1820 30 COG1913 COG1913, Predicted Zn-dependent proteases General function prediction only 14590315 Nonpathogen - hypothetical protein PH0408 2 None None None 14590002 Nonpathogen - hypothetical protein PH0047 27 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 14591638 Nonpathogen - hypothetical protein PH1894 4 COG3390 COG3390, Uncharacterized protein conserved in archaea Function unknown 14590624 Common - sugar transport system permease protein PH0754 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 14590779 Common - mannosyl-3-phosphoglycerate phosphatase PH0926 31 COG3769 COG3769, Predicted hydrolase (HAD superfamily) General function prediction only 14590039 Nonpathogen - hypothetical protein PH0087 2 None None None 14591410 Common rps4p 30S ribosomal protein S4 PH1640 123 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 14590954 Nonpathogen - hypothetical protein PH1126 2 None None None 14590342 Common - hypothetical protein PH0425 40 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 14590872 Nonpathogen - hypothetical protein PH1033 9 COG1673 COG1673, Uncharacterized protein conserved in archaea Function unknown 33359331 Nonpathogen - hypothetical protein PH0795.1n 2 COG2345 COG2345, Predicted transcriptional regulator Transcription 14590565 Common porA pyruvate ferredoxin oxidoreductase subunit alpha PH0684 117 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 14590685 Common - hypothetical protein PH0818 19 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 14590454 Nonpathogen - hypothetical protein similar to diverse transmembrane protein set PH0554 1 None None None 14591719 Common - hypothetical protein PH1984 158 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 161349997 Common - tryptophanyl-tRNA synthetase PH1921 99 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 14590879 Nonpathogen - hypothetical protein PH1041 9 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 14591341 Common - hypothetical protein PH1558 158 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 14590352 Nonpathogen - hypothetical protein PH0437 11 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14590926 Common - cystathionine gamma-synthase PH1093 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 14590934 Nonpathogen - 30S ribosomal protein S8e PH1103 34 COG2007 RPS8A, Ribosomal protein S8E Translation, ribosomal structure and biogenesis 33359364 Nonpathogen - hypothetical protein PH1130.1n 2 None None None 14591079 Common - prolyl endopeptidase PH1262 115 COG1505 COG1505, Serine proteases of the peptidase family S9A Amino acid transport and metabolism 14591327 Common - DNA-directed RNA polymerase subunit A'' PH1544 186 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 14590916 Common - hypothetical ubiquinone/menaquinone biosynthesis methyltransferase PH1081 61 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 14589994 Nonpathogen - hypothetical protein PH0036 1 None None None 14590349 Common - hypothetical protein PH0434 167 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 14591531 Common rpl2p 50S ribosomal protein L2P PH1775 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 14590795 Common - putative monovalent cation/H+ antiporter subunit B PH0943 6 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 14590843 Common - hypothetical protein PH1001 215 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 14591731 Common dcd deoxycytidine triphosphate deaminase PH1997 155 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 14590806 Common - hypothetical protein PH0954 39 COG1572 COG1572, Uncharacterized conserved protein Function unknown 33359266 Nonpathogen - hypothetical protein PH0223.1n 1 None None None 14590150 Nonpathogen - hypothetical protein PH0221 2 None None None 14590010 Common - hypothetical protein PH0057 136 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 14589974 Common - hypothetical protein PH0012 14 COG0456 RimI, Acetyltransferases General function prediction only 33359409 Nonpathogen - hypothetical protein PH1488.1n 2 None None None 14590440 Common - hypothetical protein PH0539 10 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 33359311 Nonpathogen - hypothetical protein PH0635.1n 2 None None None 14590063 Common - hypothetical protein PH0117 33 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 14590114 Common - glutaredoxin-like protein PH0178 82 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 14591756 Nonpathogen - hypothetical protein PH1899a 8 COG2892 COG2892, Uncharacterized protein conserved in archaea Function unknown 14590323 Nonpathogen - hypothetical protein PHS014 1 None None None 14590265 Common - hypothetical protein PH0355 8 COG4043 COG4043, Uncharacterized conserved protein Function unknown 14591264 Nonpathogen - hypothetical protein PH1477 23 COG1860 COG1860, Uncharacterized protein conserved in archaea Function unknown 14590157 Common - hypothetical protein PH0226 190 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 14590941 Common - ATP-dependent helicase LHR PH1110 161 COG1201 Lhr, Lhr-like helicases General function prediction only 14590754 Nonpathogen - hypothetical protein PH0898 1 None None None 14590477 Common - hypothetical protein PH0581 140 COG0432 COG0432, Uncharacterized conserved protein Function unknown 14590132 Nonpathogen - hypothetical protein PH0197 16 COG1341 COG1341, Predicted GTPase or GTP-binding protein General function prediction only 14591519 Common rps8p 30S ribosomal protein S8P PH1764 214 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 14591472 Nonpathogen - hypothetical protein PH1709 1 None None None 14591479 Common argD acetylornithine/acetyl-lysine aminotransferase PH1716 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 14591303 Nonpathogen - hypothetical protein PH1520 3 None None None 14590828 Common - hypothetical protein PH0983 106 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 14591499 Nonpathogen - hypothetical protein PH1741 1 None None None 14591489 Common - hypothetical protein PH1731 166 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 14591280 Nonpathogen - hypothetical protein PH1495 1 None None None 14591066 Common - hypothetical protein PH1246 96 COG1203 COG1203, Predicted helicases General function prediction only 14591452 Nonpathogen - hypothetical protein PH1690 1 None None None 14591039 Common - hypothetical protein PH1219 100 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 14591291 Common - NADH oxidase PH1509 245 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 14590143 Common - hypothetical protein PH0210 219 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 14590412 Common - oligopeptide transport ATP-binding protein AppF PH0507 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 14590590 Common - hypothetical protein PH0712 140 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 14590856 Nonpathogen - hypothetical protein PH1016 2 None None None 14591200 Common - hypothetical protein PH1401 24 COG1901 COG1901, Uncharacterized conserved protein Function unknown 14591457 Common - signal recognition particle protein Srp54 PH1694 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 14590274 Common - beta-glucosidase PH0366 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 14590646 Nonpathogen - hypothetical protein PH0778 1 None None None 14590403 Common - hypothetical protein PH0495 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 14591671 Common - hypothetical protein PH1928 142 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 14591114 Nonpathogen - hypothetical protein PH1304 4 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 14590105 Nonpathogen - hypothetical protein PH0168 10 COG1517 COG1517, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 14590079 Common - Na(+)/H(+) antiporter PH0136 215 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 14590632 Nonpathogen - hypothetical protein PH0763 18 COG1356 COG1356, Uncharacterized protein conserved in archaea Function unknown 14591121 Common - hypothetical protein PH1310 42 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 14590466 Common - hypothetical protein PH0567 34 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 14590664 Nonpathogen - hypothetical protein PH0796 3 None None None 14591645 Nonpathogen rpl37ae 50S ribosomal protein L37Ae PHS057 34 COG1997 RPL43A, Ribosomal protein L37AE/L43A Translation, ribosomal structure and biogenesis 14591223 Common - putative monovalent cation/H+ antiporter subunit B PH1429 53 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 14590821 Common - hypothetical protein PH0976 36 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14590715 Common - hypothetical protein PH0855 9 COG0456 RimI, Acetyltransferases General function prediction only 14591490 Nonpathogen - hypothetical protein PH1732 8 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 14591207 Common - dipeptide transport system permease protein dppC PH1411 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 14591139 Nonpathogen - hypothetical protein PH1328 20 COG1591 COG1591, Holliday junction resolvase - archaeal type DNA replication, recombination, and repair 33359287 Nonpathogen - hypothetical protein PHS011.1n 1 None None None 14591655 Common - hypothetical protein PH1912 168 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 14590177 Common - tldd protein PH0246 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 14590393 Common - chemotaxis protein methyltransferase PH0481 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 14590071 Nonpathogen - hypothetical protein PH0127 11 COG1935 COG1935, Uncharacterized conserved protein Function unknown 14591391 Common - hypothetical protein PH1616 91 COG0622 COG0622, Predicted phosphoesterase General function prediction only 14590834 Nonpathogen - hypothetical protein PH0989 24 COG2412 COG2412, Uncharacterized conserved protein Function unknown 14590501 Nonpathogen - translation initiation factor IF-2 subunit beta PH0605 34 COG1601 GCD7, Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain Translation, ribosomal structure and biogenesis 14590078 Nonpathogen - hypothetical protein PH0135 25 COG1549 COG1549, Queuine tRNA-ribosyltransferases, contain PUA domain Translation, ribosomal structure and biogenesis 14590192 Common - hypothetical protein PH0266 23 COG3129 COG3129, Predicted SAM-dependent methyltransferase General function prediction only 14590655 Common - hypothetical protein PH0786 18 COG5305 COG5305, Predicted membrane protein Function unknown 14590182 Common - hypothetical protein PH0253 66 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 14591032 Common - thermonuclease PH1212 84 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 14591640 Common - bifunctional inositol-1 monophosphatase/fructose-1,6-bisphosphatase PH1897 209 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 14591231 Common - NADH-plastoquinone oxidoreductase subunit PH1440 139 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 14590598 Common - aspartate carbamoyltransferase regulatory subunit PH0721 64 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 14590301 Nonpathogen - hypothetical protein PH0393 1 None None None 14590797 Nonpathogen - hypothetical protein PH0945 1 None None None 14591289 Common - hypothetical protein PH1506 27 COG2014 COG2014, Uncharacterized conserved protein Function unknown 14591352 Common - hypothetical protein PH1571 33 COG0628 PerM, Predicted permease General function prediction only 14590722 Nonpathogen - hypothetical protein PH0862 2 None None None 14590747 Common - NADH oxidase PH0890 232 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 14590026 Nonpathogen - hypothetical protein PH0072 2 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 14590276 Nonpathogen - hypothetical protein PH0368 4 COG1543 COG1543, Uncharacterized conserved protein Function unknown 14591100 Common - peptidase PH1288 194 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 33359391 Nonpathogen - hypothetical protein PHS037.1n 2 None None None 14590179 Nonpathogen - hypothetical protein PH0250 2 None None None 14590808 Nonpathogen - hypothetical protein PH0958 27 COG2047 COG2047, Uncharacterized protein (ATP-grasp superfamily) General function prediction only 14591029 Common - hypothetical protein PH1208 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 33359425 Common - hypothetical protein PH1750.1n 41 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 14590674 Common - oligopeptide binding protein APPA PH0807 216 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 33359322 Nonpathogen - hypothetical protein PH0713.1n 1 None None None 14590233 Common - phosphoribosylaminoimidazole synthetase PH0316 234 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 14591378 Nonpathogen - ribonuclease P protein component 4 PH1601 27 COG2023 RPR2, RNase P subunit RPR2 Translation, ribosomal structure and biogenesis 14591155 Nonpathogen purP 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase PH1348 20 COG1759 COG1759, ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) General function prediction only 14591022 Nonpathogen - hypothetical protein PH1199 2 None None None 14590734 Common - putative oxidoreductase PH0876 233 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 14590998 Nonpathogen - hypothetical protein PH1172 2 None None None 14591589 Nonpathogen - chromatin protein PHS053 28 COG1581 Ssh10b, Archaeal DNA-binding protein Transcription 33359346 Nonpathogen - hypothetical protein PH0940.1n 2 None None None 14591211 Nonpathogen - flap endonuclease-1 PH1415 34 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 14590363 Common - hypothetical protein PH0449 24 COG3372 COG3372, Uncharacterized conserved protein Function unknown 14591505 Common - hypothetical protein PH1748 81 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 14590449 Nonpathogen - flagellin PH0549 7 COG1681 FlaB, Archaeal flagellins Cell motility and secretion 14591540 Nonpathogen - archaeal histon PHS051 20 COG2036 HHT1, Histones H3 and H4 Chromatin structure and dynamics 14591722 Common - O-sialoglycoprotein endopeptidase PH1987 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 14591202 Common - mRNA 3'-end processing factor, putative PH1404 166 COG1782 COG1782, Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain General function prediction only 14591229 Common - NADH-ubiquinone oxidoreductase subunit PH1437 194 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 14590383 Common - membrane protein PH0470 220 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 14591432 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit gamma PH1663 78 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 14590012 Common - hypothetical protein PH0059 30 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 14590895 Nonpathogen - hypothetical protein PH1058 1 None None None 14590525 Common - hypothetical protein PH0634 101 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 14589986 Common - hypothetical protein PH0025 19 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 14590141 Common - translation initiation factor IF-2B subunit delta PH0208 132 COG1184 GCD2, Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 33359309 Nonpathogen - hypothetical protein PH0619.1n 2 None None None 14591282 Nonpathogen rpl7ae 50S ribosomal protein L7Ae PH1496 35 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 14591568 Common - hypothetical protein PH1816 74 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 14591013 Nonpathogen - hypothetical protein PH1188 3 COG0433 COG0433, Predicted ATPase General function prediction only 14590937 Nonpathogen - hypothetical protein PH1106 1 None None None 14591128 Common - hypothetical protein PH1316 80 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 161350012 Common - multiple sugar-binding transport ATP-binding protein PH0194 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 14590188 Nonpathogen - hypothetical protein PH0261 20 COG1326 COG1326, Uncharacterized archaeal Zn-finger protein General function prediction only 33359324 Nonpathogen - hypothetical protein PH0716.1n 3 None None None 14591526 Nonpathogen - ribonuclease P protein component 1 PH1771 23 COG1588 POP4, RNase P/RNase MRP subunit p29 Translation, ribosomal structure and biogenesis 14591254 Common - hypothetical protein PH1465 54 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 14590535 Common - GTP-binding protein PH0645 105 COG1161 COG1161, Predicted GTPases General function prediction only 33359399 Nonpathogen - hypothetical protein PH1360.1n 2 None None None 14591116 Common - methylmalonyl-CoA mutase PH1306 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 14590163 Common - L-asparaginase PH0232 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 14590294 Common - hypothetical protein PH0385 179 COG0714 COG0714, MoxR-like ATPases General function prediction only 14591102 Common - cytochrome-c3 hydrogenase subunit gamma PH1291 114 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 14590865 Common - membrane dipeptidase PH1026 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 33359292 Nonpathogen - hypothetical protein PH0430.1n 3 COG4906 COG4906, Predicted membrane protein Function unknown 14591383 Nonpathogen - hypothetical protein PH1608 14 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 14590985 Nonpathogen - hypothetical protein PH1158 1 None None None 14590703 Nonpathogen - hypothetical protein PH0842 3 None None None 161349995 Common - dihydroorotate dehydrogenase electron transfer subunit PH1965 122 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 14591662 Nonpathogen - hypothetical protein PH1920 2 None None None 14590359 Common - hypothetical O-sialoglycoprotein endopeptidase PH0445 92 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 14590391 Common - methyl-accepting chemotaxis protein PH0479 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 14590762 Common - DNA-binding protein PH0909 84 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 14591608 Nonpathogen - hypothetical protein PH1861 1 None None None 14591168 Common - hypothetical protein PH1363 50 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 161350006 Nonpathogen - hypothetical protein PHS039 1 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 14590053 Common - hypothetical protein PH0103 26 COG2810 COG2810, Predicted type IV restriction endonuclease Defense mechanisms 14590612 Common - hypothetical protein PH0737 86 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 14590333 Nonpathogen - hypothetical protein PH0415 1 None None None 14590378 Common - hypothetical protein PH0466 57 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 14590915 Nonpathogen - hypothetical protein PH1080 5 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 33359404 Common - hypothetical protein PHS039.1n 26 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 14590966 Common - indolepyruvate ferredoxin oxidoreductase alpha subunit PH1138 132 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 14591407 Nonpathogen - 50S ribosomal protein L18e PH1636 34 COG1727 RPL18A, Ribosomal protein L18E Translation, ribosomal structure and biogenesis 14591188 Common - hypothetical protein PH1385 188 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 14591681 Common - hypothetical protein PH1939 20 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 14590957 Common pyrE orotate phosphoribosyltransferase PH1128 243 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 14590490 Common - hypothetical protein PH0594 109 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 14590567 Nonpathogen - ORFZ protein PH0686 8 None None None 14590571 Nonpathogen - hypothetical protein PH0692 1 None None None 14591363 Common - hypothetical protein PH1585 185 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 14590225 Common - hypothetical protein PH0305 34 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 14590257 Nonpathogen - hypothetical protein PH0345 1 None None None 14591198 Common - peptidyl-prolyl cis-trans isomerase PH1399 138 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 14591042 Nonpathogen - hypothetical protein PH1223 29 COG1779 COG1779, C4-type Zn-finger protein General function prediction only 14591469 Nonpathogen - hypothetical Fe-S oxidoreductase PH1705 35 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 33359272 Nonpathogen - hypothetical protein PH0317.2n 1 COG5378 COG5378, Predicted nucleotide-binding protein General function prediction only 14591230 Common - NADH-ubiquinone oxidoreductase subunit PH1439 191 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 14590096 Common - transport-ATP binding protein PH0157 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 14590212 Common - hypothetical protein PH0289 32 COG1510 COG1510, Predicted transcriptional regulators Transcription 14591748 Nonpathogen rps17E 30S ribosomal protein S17e PH1316a 33 COG1383 RPS17A, Ribosomal protein S17E Translation, ribosomal structure and biogenesis 14591610 Nonpathogen - hypothetical protein PH1863 5 COG4342 COG4342, Uncharacterized protein conserved in archaea Function unknown 14589972 Common - hypothetical protein PH0010 78 COG2078 AMMECR1, Uncharacterized conserved protein Function unknown 33359268 Nonpathogen - hypothetical protein PH0271.1n 2 None None None 33359276 Nonpathogen - hypothetical protein PH0373.1n 3 None None None 14591680 Common - D-arabino 3-hexulose 6-phosphate formaldehyde lyase PH1938 113 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 33359358 Common - hypothetical protein PH1050 14 None None None 33359371 Nonpathogen - hypothetical protein PH1185.1n 1 None None None 14590644 Common - hypothetical protein PH0776 189 COG0714 COG0714, MoxR-like ATPases General function prediction only 14590692 Common - hypothetical protein PH0825 15 COG1510 COG1510, Predicted transcriptional regulators Transcription 14590198 Common - hypothetical protein PH0274 101 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 14590671 Nonpathogen - hypothetical protein PH0804 8 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 14590245 Common - hypothetical protein PH0329 182 COG0714 COG0714, MoxR-like ATPases General function prediction only 14591366 Common - hypothetical protein PH1588 185 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 14590474 Nonpathogen - hypothetical protein PH0578 22 COG2403 COG2403, Predicted GTPase General function prediction only 33359283 Nonpathogen - hypothetical protein PHS008.3n 1 None None None 14590606 Nonpathogen - hypothetical protein PH0729 1 None None None 14590037 Nonpathogen - hypothetical protein PH0084 7 COG1818 COG1818, Predicted RNA-binding protein, contains THUMP domain General function prediction only 33359387 Nonpathogen - hypothetical protein PH1295.2n 2 None None None 33359412 Nonpathogen - hypothetical protein PH1537.1n 2 None None None 14590557 Common - hypothetical protein PH0675 61 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 14590421 Common - thermostable aminopeptidase PH0519 90 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 14591310 Nonpathogen - hypothetical protein PH1528 2 None None None 14591591 Common - hypothetical protein PH1842 161 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 14590697 Nonpathogen - hypothetical protein PH0831 1 None None None 14591538 Nonpathogen - hypothetical protein PH1781 4 COG2450 COG2450, Uncharacterized conserved protein Function unknown 14591387 Nonpathogen - hypothetical protein PH1612 6 COG1844 COG1844, Uncharacterized protein conserved in archaea Function unknown 14590081 Common - 4-aminobutyrate aminotransferase PH0138 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 14591053 Nonpathogen - hypothetical protein PH1234 26 COG1831 COG1831, Predicted metal-dependent hydrolase (urease superfamily) General function prediction only 33359351 Nonpathogen - putative amin-acid transporter PH0974.1n 2 None None None 14590680 Common - hypothetical protein PH0813 48 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 14591179 Nonpathogen - hypothetical protein PH1376 2 None None None 14591547 Common - hypothetical protein PH1789 147 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 33359337 Common - Predicted ATPase of the AAA superfamily PH0840m 33 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14591561 Nonpathogen - hypothetical protein PH1808 32 COG1395 COG1395, Predicted transcriptional regulator Transcription 14591704 Common - hypothetical protein PH1966 51 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 14591582 Common - hypothetical protein PH1832 13 COG4720 COG4720, Predicted membrane protein Function unknown 14590122 Common - hypothetical protein PH0187 49 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 14591706 Common - alanyl-tRNA synthetase PH1969 247 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 14590203 Common - hypothetical protein PH0279 49 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 14590042 Nonpathogen - hypothetical protein PH0090 5 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 33359249 Nonpathogen - hypothetical protein PH0059.1n 2 None None None 14590455 Nonpathogen - hypothetical protein PH0555 9 COG3354 FlaG, Putative archaeal flagellar protein G Cell motility and secretion 14591346 Common - DNA topoisomerase VI subunit B PH1564 34 COG1389 COG1389, DNA topoisomerase VI, subunit B DNA replication, recombination, and repair 14590287 Common - UDP-glucose 4-epimerase PH0378 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 14590657 Common - hypothetical protein PH0788 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 161349994 Nonpathogen rpl12p 50S ribosomal protein L12P PH1998 33 COG2058 RPP1A, Ribosomal protein L12E/L44/L45/RPP1/RPP2 Translation, ribosomal structure and biogenesis 14591433 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta PH1665 111 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 14589995 Common - cofactor-independent phosphoglycerate mutase PH0037 52 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 33359318 Nonpathogen - hypothetical protein PH0696.1n 1 None None None 14591603 Nonpathogen - signal recognition particle protein Srp19 PHS054 17 COG1400 SEC65, Signal recognition particle 19 kDa protein Intracellular trafficking and secretion 14591578 Nonpathogen - N(2),N(2)-dimethylguanosine tRNA methyltransferase PH1829 38 COG1867 TRM1, N2,N2-dimethylguanosine tRNA methyltransferase Translation, ribosomal structure and biogenesis 14590662 Nonpathogen - hypothetical protein PH0794 5 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 14590811 Common - hypothetical protein PH0963 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 14590918 Common - hypothetical protein PH1083 32 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 14590701 Common - alpha-mannosidase PH0835 51 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 14589965 Nonpathogen nusG transcription antitermination protein NusG PH0002 34 COG0250 NusG, Transcription antiterminator Transcription 14591034 Common - cytoplasmic protein PH1214 84 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 14591329 Common - DNA-directed RNA polymerase subunit beta PH1546 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 14590017 Nonpathogen - hypothetical protein PH0063 4 None None None 14590770 Nonpathogen - hypothetical protein PH0916 3 COG2254 COG2254, Predicted HD superfamily hydrolase, possibly a nuclease DNA replication, recombination, and repair 14590164 Common - hypothetical protein PH0233 219 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 14590858 Nonpathogen - hypothetical protein PH1018 1 None None None 14590480 Common - modification methylase PH0584 63 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 14590716 Common - hypothetical protein PH0856 77 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 14590622 Nonpathogen - hypothetical protein PH0752 1 None None None 14591653 Nonpathogen - hypothetical protein PH1909 31 COG1909 COG1909, Uncharacterized protein conserved in archaea Function unknown 14591091 Common - malate dehydrogenase PH1277 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 14591069 Nonpathogen - hypothetical protein PH1251 7 None None None 14590526 Common - hypothetical protein PH0635 79 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 14590587 Nonpathogen - hypothetical protein PH0709 32 COG1439 COG1439, Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module General function prediction only 14590573 Common - hypothetical protein PH0694 9 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 14590841 Common - pyrazinamidase/nicotinamidase PH0999 157 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 14591126 Nonpathogen - hypothetical protein PH1314 4 COG1851 COG1851, Uncharacterized conserved protein Function unknown 14591019 Nonpathogen - hypothetical protein PH1194 3 None None None 33359400 Nonpathogen - hypothetical protein PH1372.1n 1 None None None 14591563 Nonpathogen - hypothetical protein PH1810 1 None None None 14590893 Common - hypothetical protein PH1056 60 COG1720 COG1720, Uncharacterized conserved protein Function unknown 14591045 Nonpathogen - hypothetical protein PH1226 3 COG1433 COG1433, Uncharacterized conserved protein Function unknown 14589979 Common - thermophilic factor PH0017 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 14591623 Nonpathogen - hypothetical protein PH1876 28 COG1325 COG1325, Predicted exosome subunit Translation, ribosomal structure and biogenesis 14590874 Common - hypothetical protein PH1035 170 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 14591738 Nonpathogen - DNA-directed RNA polymerase subunit L PH0041a 18 COG1761 RPB11, DNA-directed RNA polymerase, subunit L Transcription 14591275 Common - transport protein PH1490 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 14590194 Common - hypothetical protein PH0268 58 COG5270 COG5270, PUA domain (predicted RNA-binding domain) Translation, ribosomal structure and biogenesis 14591062 Nonpathogen - hypothetical protein PH1243 2 None None None 14590185 Nonpathogen - hypothetical protein PH0258 3 None None None 14590948 Nonpathogen - hypothetical protein PH1118 7 COG4345 COG4345, Uncharacterized protein conserved in archaea Function unknown 14590513 Common - DNA topoisomerase I PH0622 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 14591293 Common - erythrocyte band7 integral membrane protein PH1511 202 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 14590416 Nonpathogen - hypothetical protein PH0514 2 None None None 14591425 Nonpathogen - hypothetical protein PH1656 11 COG2411 COG2411, Uncharacterized conserved protein Function unknown 14590285 Common - putative aminotransferase PH0377 232 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 14591237 Common - NADH dehydrogenase subunit D PH1447 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 14590880 Common - amidohydrolase PH1043 175 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 14591320 Common truD tRNA pseudouridine synthase D PH1538 91 COG0585 COG0585, Uncharacterized conserved protein Function unknown 14590952 Common - hypothetical protein PH1123 38 COG1855 COG1855, ATPase (PilT family) General function prediction only 14590452 Nonpathogen - hypothetical protein PH0552 4 COG3352 FlaC, Putative archaeal flagellar protein C Cell motility and secretion 14590408 Common - hypothetical protein PH0502 190 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 14591412 Common - hypothetical protein PH1642 109 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 33359382 Nonpathogen - hypothetical protein PH1253.1n 1 None None None 14590868 Nonpathogen - hypothetical protein PH1030 1 None None None 14590414 Common - beta-galactosidase precursor PH0511 30 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 14590464 Nonpathogen - hypothetical protein PH0565 3 None None None 14590784 Common - hypothetical protein PH0932 94 COG0433 COG0433, Predicted ATPase General function prediction only 14590620 Common - hypothetical protein PH0749 22 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 14590475 Nonpathogen - hypothetical protein PH0579 2 COG5418 COG5418, Predicted secreted protein Function unknown 33359349 Nonpathogen - hypothetical protein PH0954.1n 1 None None None 14591652 Common - DNA-directed RNA polymerase subunit E' PH1908 58 COG1095 RPB7, DNA-directed RNA polymerase, subunit E' Transcription 14590641 Common - hypothetical protein PH0772 35 None None None 14590531 Nonpathogen - hypothetical protein PH0641 34 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 14591695 Common - phosphoribosylformylglycinamidine synthase subunit I PH1955 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 14590154 Common - hypothetical protein PH0223 16 COG2029 COG2029, Uncharacterized conserved protein Function unknown 14591285 Common - 4-aminobutyrate aminotransferase PH1501 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 14591209 Common - dipeptide transport ATP-binding protein dppF PH1413 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 14591225 Common - putative monovalent cation/H+ antiporter subunit D PH1431 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 14591137 Nonpathogen - hypothetical protein PH1326 2 COG2457 COG2457, Uncharacterized conserved protein Function unknown 14591393 Common - UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase PH1618 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 33359326 Nonpathogen - hypothetical protein PH0744.1n 19 COG3357 COG3357, Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon Transcription 14591005 Nonpathogen - hypothetical protein PH1180 3 None None None 14591146 Nonpathogen - hypothetical protein PH1339 2 None None None 14591720 Common secD preprotein translocase subunit SecD PH1985 140 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 14591492 Nonpathogen - hypothetical protein PH1734 26 COG1633 COG1633, Uncharacterized conserved protein Function unknown 14591592 Common - hypothetical protein PH1844 233 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 14590022 Nonpathogen - hypothetical protein PH0068 1 None None None 14591529 Common rpl22p 50S ribosomal protein L22P PH1773 37 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 14590321 Nonpathogen - hypothetical protein PHS012 1 None None None 14590546 Common - hypothetical protein PH0661 72 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 33359289 Nonpathogen - hypothetical protein PHS014.4n 1 None None None 14591444 Common - hypothetical protein PH1680 168 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 14591488 Nonpathogen - hypothetical protein PH1730 15 COG2454 COG2454, Uncharacterized conserved protein Function unknown 14590000 Common - hypothetical protein PH0045 154 COG1522 Lrp, Transcriptional regulators Transcription 14590073 Nonpathogen - hypothetical protein PH0129 14 COG1967 COG1967, Predicted membrane protein Function unknown 14590148 Nonpathogen - hypothetical protein PH0216 4 COG5608 COG5608, Conserved secreted protein Function unknown 14590889 Common - hypothetical protein PH1052 31 COG3535 COG3535, Uncharacterized conserved protein Function unknown 33359444 Nonpathogen - hypothetical protein PH1956.1n 2 None None None 14591305 Nonpathogen - hypothetical protein PH1522 4 COG5064 SRP1, Karyopherin (importin) alpha Intracellular trafficking and secretion 14591450 Common gltX glutamyl-tRNA synthetase PH1686 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 14591150 Nonpathogen - hypothetical protein PH1343 5 COG5306 COG5306, Uncharacterized conserved protein Function unknown 14590489 Common - hypothetical protein PH0593 172 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 14590328 Nonpathogen - hypothetical protein PH0411 1 None None None 14590065 Common - hypothetical protein PH0120 101 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 14590804 Common - hypothetical protein PH0952 22 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 14590907 Common - hypothetical protein PH1071 162 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 14590765 Nonpathogen - hypothetical protein PH0910 6 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 14590592 Nonpathogen - hypothetical protein PH0714 1 None None None 14591068 Nonpathogen - hypothetical protein PH1250 14 COG1857 COG1857, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 14591483 Common - 3-isopropylmalate dehydrogenase PH1722 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 14590793 Common - putative monovalent cation/H+ antiporter subunit D PH0941 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 14590648 Nonpathogen - hypothetical protein PH0780 1 None None None 14591085 Common - hypothetical protein PH1269 130 COG1881 COG1881, Phospholipid-binding protein General function prediction only 14590107 Common - hypothetical protein PH0170 14 COG1857 COG1857, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 14590138 Common - hypothetical protein PH0205 140 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 14590029 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase PH0075 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 14590861 Common - sugar-phosphate nucleotydyl transferase PH1022 240 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 14591616 Nonpathogen - hypothetical protein PH1869 1 None None None 33359338 Nonpathogen - hypothetical protein PH0870.2n 1 None None None 14591449 Nonpathogen - hypothetical protein PH1685 1 None None None 14590211 Common - hypothetical protein PH0287 87 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 14591678 Common - hypothetical protein PH1936 210 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 14591044 Common - farnesyl cysteine carboxyl-methyltransferase PH1225 31 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 14590939 Nonpathogen - hypothetical protein PH1108 1 None None None 14591422 Common - ABC transporter PH1653 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 14590523 Common - Gufa protein PH0632 94 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 14590240 Common - phosphoribosylamine--glycine ligase PH0323 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 14590098 Common - RNA 2'-phosphotransferase-like protein PH0160 43 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 14591558 Common - 3-hydroxy-3-methylglutaryl coenzyme A reductase PH1805 65 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 14590235 Nonpathogen - hypothetical protein PH0317 2 None None None 14591109 Nonpathogen - hypothetical protein PH1299 1 None None None 14590381 Nonpathogen - hypothetical protein PH0469 4 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 14591148 Nonpathogen - hypothetical protein PH1341 2 None None None 14590575 Nonpathogen - hypothetical protein PH0696 9 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 33359294 Nonpathogen - putative glycosyl transferase PH0457.1n 1 COG2445 COG2445, Uncharacterized conserved protein Function unknown 14590964 Common - hypothetical protein PH1136 14 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 14590308 Common - glycosyl transferase PH0401 189 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 14590617 Nonpathogen - hypothetical protein PH0744 3 None None None 14590684 Nonpathogen - hypothetical protein PH0817 1 None None None 14591219 Common - thioredoxin reductase PH1426 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 14591580 Common - glyceraldehyde-3-phosphate dehydrogenase PH1830 58 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 14590296 Nonpathogen - hypothetical protein PH0388 1 None None None 33359385 Nonpathogen - hypothetical protein PH1282.1n 2 None None None 14590863 Nonpathogen - hypothetical protein PH1024 2 None None None 14591080 Common - hypothetical protein PH1263 32 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14591087 Common - hypothetical protein PH1271 10 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 14590317 Common - hypothetical protein PHS008 26 COG2442 COG2442, Uncharacterized conserved protein Function unknown 14591248 Common - hypothetical protein PH1458 168 COG1964 COG1964, Predicted Fe-S oxidoreductases General function prediction only 14591503 Common - hypothetical protein PH1746 75 COG0622 COG0622, Predicted phosphoesterase General function prediction only 161350004 Common rpl18p 50S ribosomal protein L18P PH1758 39 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 14590278 Common - hypothetical protein PH0370 11 COG5340 COG5340, Predicted transcriptional regulator Transcription 14590991 Common - hypothetical protein PH1164 31 COG2108 COG2108, Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme General function prediction only 14591213 Nonpathogen - hypothetical protein PH1418 3 None None None 14590725 Common - hypothetical protein PH0865 43 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 14590024 Common - hypothetical protein PH0070 168 COG2962 RarD, Predicted permeases General function prediction only 14591157 Common - ATP-binding transport protein PH1350 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 14590555 Common - hypothetical protein PH0673 49 COG2431 COG2431, Predicted membrane protein Function unknown 14590438 Common - hypothetical protein PH0537 10 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 14590756 Common - putative helicase PH0900 168 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 14591542 Nonpathogen - hypothetical protein PH1784 24 COG1913 COG1913, Predicted Zn-dependent proteases General function prediction only 14590271 Common - hypothetical protein PH0361 43 COG1297 COG1297, Predicted membrane protein Function unknown 14591717 Common - V-type ATP synthase subunit I PH1981 49 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 14590505 Common - cell division inhibitor MinD PH0612 230 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 14591287 Common - hypothetical protein PH1503 54 COG1993 COG1993, Uncharacterized conserved protein Function unknown 14590446 Common - hypothetical protein PH0545 43 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 14590331 Common - glucose-1-phosphate thymidylyltransferase PH0413 235 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 14590930 Common - hypothetical protein PH1099 6 COG3595 COG3595, Uncharacterized conserved protein Function unknown 14590369 Nonpathogen - putative nucleotidyltransferase PH0458 17 None None None 14591403 Common - hypothetical protein PH1630 245 COG0148 Eno, Enolase Carbohydrate transport and metabolism 14590745 Common - hypothetical protein PH0888 149 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 14591683 Common maf Maf-like protein PH1941 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 14590447 Nonpathogen - flagellin PH0546 6 COG1681 FlaB, Archaeal flagellins Cell motility and secretion 14591669 Common - glucose-1-phosphate thymidylyltransferase PH1925 241 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 33359393 Nonpathogen - hypothetical protein PH1340 2 None None None 14591533 Nonpathogen - hypothetical protein PHS050 1 None None None 14591161 Common - pyridoxine biosynthesis protein PH1355 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 14591141 Nonpathogen - hypothetical protein PH1333 2 None None None 14590343 Common - hypothetical protein PH0426 90 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 33359363 Nonpathogen - 50S ribosomal protein L21e PHS032 34 COG2139 RPL21A, Ribosomal protein L21E Translation, ribosomal structure and biogenesis 14591464 Common - hypothetical protein PH1701 155 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 14590040 Nonpathogen - hypothetical protein PH0088 5 COG1822 COG1822, Predicted archaeal membrane protein Function unknown 14590732 Common - hypothetical protein PH0873 36 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 14591348 Common - hypothetical protein PH1567 66 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 14590243 Common - hypothetical protein PH0326 123 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 14591338 Nonpathogen - hypothetical protein PH1555 4 None None None 14591551 Nonpathogen - hypothetical protein PH1796 1 None None None 14590519 Common - methionine aminopeptidase PH0628 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 14590689 Common - hypothetical protein PH0822 34 COG1433 COG1433, Uncharacterized conserved protein Function unknown 14591317 Common - hypothetical protein PH1535 34 COG1379 COG1379, Uncharacterized conserved protein Function unknown 14590120 Nonpathogen - hypothetical protein PH0185 4 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 14590472 Common - hypothetical protein PH0575 183 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 33359300 Nonpathogen - 50S ribosomal protein L31e PH0529a 29 COG2097 RPL31A, Ribosomal protein L31E Translation, ribosomal structure and biogenesis 14590035 Common - fructose-bisphosphate aldolase PH0082 97 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 33359335 Common - Predicted ATPase of the AAA superfamily PH0830m 34 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 14590338 Common - lipopolysaccharide O-side chain biosynthesis protein (O-antigen transpoter) PH0421 125 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 14590693 Nonpathogen - hypothetical protein PH0826 1 None None None 14591334 Nonpathogen - exosome complex RNA-binding protein Rrp4 PH1551 24 COG1097 RRP4, RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain) Translation, ribosomal structure and biogenesis 33359353 Nonpathogen - hypothetical protein PH1004.1n 1 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 14591055 Common - ferrichrome transport permease protein PH1236 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 14591373 Nonpathogen - hypothetical protein PH1595 5 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 14591385 Nonpathogen - hypothetical protein PH1610 8 COG3371 COG3371, Predicted membrane protein Function unknown 14591252 Common - glutamyl-tRNA(Gln) amidotransferase subunit D PH1463 137 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 14591626 Common - hypothetical protein PH1879 23 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 14590067 Nonpathogen - DNA polymerase II small subunit PH0123 24 COG1311 HYS2, Archaeal DNA polymerase II, small subunit/DNA polymerase delta, subunit B DNA replication, recombination, and repair 14590699 Common - hypothetical protein PH0833 135 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 14590060 Common moaA molybdenum cofactor biosynthesis protein A PH0114 207 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 14590637 Common - cell division protein FtsZ PH0769 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 14591749 Common mnhF putative monovalent cation/H+ antiporter subunit F PH1427a 91 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 14590428 Nonpathogen - prefoldin subunit alpha PH0527 9 COG1730 GIM5, Predicted prefoldin, molecular chaperone implicated in de novo protein folding Posttranslational modification, protein turnover, chaperones 33359254 Nonpathogen - hypothetical protein PH0081.1n 2 None None None 14591742 Nonpathogen rpl39e 50S ribosomal protein L39e PH0529b 21 COG2167 RPL39, Ribosomal protein L39E Translation, ribosomal structure and biogenesis 14590483 Nonpathogen - hypothetical protein PH0587 2 None None None 14590214 Common - 2-amino-3-ketobutyrate coenzyme A ligase PH0292 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 14590614 Common - hydrogenase expression/formation protein PH0739 195 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 14590223 Common - Na(+)/H(+) antiporter PH0302 204 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 14590678 Common - oligopeptide transport ATP-binding protein APPF PH0811 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 14590267 Nonpathogen - hypothetical protein PH0357 2 None None None 14591606 Nonpathogen - hypothetical protein PH1859 1 None None None 14590055 Common - hypothetical protein PH0107 186 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 14590259 Common - hypothetical protein PH0347 49 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 33359274 Nonpathogen - hypothetical protein PH0321 2 None None None 14591003 Nonpathogen - hypothetical protein PH1178 1 None None None 14591376 Nonpathogen - hypothetical protein PH1599 4 COG4003 COG4003, Uncharacterized protein conserved in archaea Function unknown 14590601 Common - hypothetical mRNA 3'-end processing factor PH0724 82 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 14591474 Common - hypothetical protein PH1711 108 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 14591186 Common - hypothetical protein PH1383 32 COG1433 COG1433, Uncharacterized conserved protein Function unknown 14590709 Common - hypothetical protein PH0848 168 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 33359278 Nonpathogen - hypothetical protein PH0381.1n 1 None None None 14591279 Nonpathogen - hypothetical protein PH1494 2 None None None 14590569 Nonpathogen - hypothetical protein PH0690 19 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 14591195 Nonpathogen - hypothetical protein PH1394 2 None None None 14591361 Common - tryptophan synthase subunit beta PH1583 225 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 14590876 Common - hypothetical protein PH1038 153 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 14591708 Common - hypothetical protein PH1971 86 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 14591369 Common - ferripyochelin binding protein PH1591 214 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 14590630 Common - hypothetical protein PH0760 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 14590354 Common - competence damage-inducible protein A PH0439 163 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 33359419 Common - hypothetical protein PH1669.1n 61 COG1872 COG1872, Uncharacterized conserved protein Function unknown 33359377 Nonpathogen - hypothetical protein PH1212.1n 5 COG1531 COG1531, Uncharacterized protein conserved in archaea Function unknown