Haemophilus influenzae Rd KW20, complete genome NC_000907 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 16273668 Common - Hsf-like protein HI1731a 39 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 16273488 Common - hypothetical protein HI1598 58 COG3025 COG3025, Uncharacterized conserved protein Function unknown 30995364 Common - transcriptional regulator HI0224 156 COG1522 Lrp, Transcriptional regulators Transcription 16272266 Common ruvB Holliday junction DNA helicase B HI0312 230 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 16273636 Common cydD ABC-type transport system ATPase component HI0663m 248 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 16273348 Common sspA stringent starvation protein A HI1441 102 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16272076 Common dapE succinyl-diaminopimelate desuccinylase HI0102 222 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 16273035 Common xylG D-xylose ABC transporter ATP-binding protein HI1110 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 16272807 Common - lipopolysaccharide biosynthesis protein HI0867 22 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 16273630 Common - integral membrane protein possible transporter HI0050m 126 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 16272337 Common - outer membrane protein HI0389 26 COG3065 Slp, Starvation-inducible outer membrane lipoprotein Cell envelope biogenesis, outer membrane 16272151 Common - transcriptional regulator HI0186 73 COG0789 SoxR, Predicted transcriptional regulators Transcription 16272400 Common - hypothetical protein HI0452 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 16272861 Common glyS glycyl-tRNA synthetase subunit beta HI0924 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 16273591 Common - hypothetical protein HI1704 112 COG0795 COG0795, Predicted permeases General function prediction only 16272217 Common - putative deoxyribonucleotide triphosphate pyrophosphatase HI0260 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 16272426 Common atpD F0F1 ATP synthase subunit beta HI0479 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 16272494 Common - lipooligosaccharide biosynthesis protein HI0550 15 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 16272204 Common tgt queuine tRNA-ribosyltransferase HI0244 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 16272332 Common tolR colicin uptake protein TolR HI0384 98 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 16272235 Common - hypothetical protein HI0277 87 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 16273287 Common - hypothetical protein HI1376 15 None None None 16273328 Pathogen - hypothetical protein HI1423 1 None None None 16273127 Common purF amidophosphoribosyltransferase HI1207 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 16273144 Common - translation initiation factor Sui1 HI1225 53 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 161350017 Common nrfA cytochrome c nitrite reductase HI1069 40 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 16272315 Common - hypothetical protein HI0367 55 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 16273420 Common - hypothetical protein HI1520 28 COG3299 XkdT, Uncharacterized homolog of phage Mu protein gp47 Function unknown 16273045 Common oppF oligopeptide ABC transporter ATP-binding protein HI1120 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 30995420 Common - hypothetical protein HI1064 56 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 16273237 Pathogen - hypothetical protein HI1327 1 None None None 16272248 Common - transcriptional regulator MerR family HI0293 142 COG0789 SoxR, Predicted transcriptional regulators Transcription 16272431 Common atpE F0F1 ATP synthase subunit C HI0484 125 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 161350025 Common rpsJ 30S ribosomal protein S10 HI0776 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 16273120 Common cysB transcriptional regulator CysB HI1200 191 COG0583 LysR, Transcriptional regulator Transcription 16272624 Common ilvC ketol-acid reductoisomerase HI0682 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 16272898 Common - hypothetical protein HI0960 4 COG5633 COG5633, Predicted periplasmic lipoprotein General function prediction only 16273294 Common rsgA ferritin HI1385 85 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 30995406 Common - nucleoid-associated protein NdpA HI0839 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 16272846 Common secA preprotein translocase subunit SecA HI0909 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 16273065 Common murC UDP-N-acetylmuramate--L-alanine ligase HI1139 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 30995415 Common - hypothetical protein HI0984 85 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 16272251 Common hopD type 4 prepilin-like protein specific leader peptidase HI0296 56 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 16272438 Common luxS S-ribosylhomocysteinase HI0491 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 16272695 Common murQ N-acetylmuramic acid-6-phosphate etherase HI0754 98 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 16272742 Common rpS11 30S ribosomal protein S11 HI0800 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 16273506 Common purK phosphoribosylaminoimidazole carboxylase ATPase subunit HI1616 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 30995457 Pathogen ftsN rep protein/cell division protein HI1571.1 1 None None None 16272119 Common hflK HflK HI0151 214 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 16272395 Common fruK 1-phosphofructokinase HI0447 113 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 16273155 Common - hypothetical protein HI1236 17 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 16272241 Common - aminotransferase AlaT HI0286 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 16272096 Common fbpC ferric transporter ATP-binding subunit HI0126 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 30995448 Common - hypothetical protein HI1418 39 COG3617 COG3617, Prophage antirepressor Transcription 16272101 Common - hypothetical protein HI0134 4 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 16272127 Common psd phosphatidylserine decarboxylase HI0160 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 16272798 Common - hypothetical protein HI0858 189 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 16273643 Common - TPR-repeat-containing protein HI1097m 35 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 16273273 Common pntB pyridine nucleotide transhydrogenase HI1363 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 30995372 Common - hypothetical protein HI0398 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 16272458 Common rpoC DNA-directed RNA polymerase subunit beta' HI0514 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 16272917 Common - hypothetical protein HI0979 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 16273059 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase HI1133 213 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 16272058 Common trxM thioredoxin HI0084 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 16272386 Common comB competence protein B HI0438 3 None None None 16272636 Common - hypothetical protein HI0694 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 16272188 Common nhaA Na+/H+ antiporter HI0225 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 16273135 Common pfs 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase HI1216 123 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 16272881 Common ribD riboflavin biosynthesis protein HI0944 224 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 16272791 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein B HI0851 114 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 16272057 Common - hypothetical protein HI0083 3 None None None 16273537 Common dld D-lactate dehydrogenase HI1649 73 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 30995383 Common tdk thymidine kinase HI0529 94 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 16272765 Common mglC beta-methylgalactoside transporter inner membrane component HI0824 114 COG4211 MglC, ABC-type glucose/galactose transport system, permease component Carbohydrate transport and metabolism 16273502 Common - multidrug efflux protein HI1612 175 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 16272446 Common rbsA D-ribose transporter ATP binding protein HI0502 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 16272018 Common - hypothetical protein HI0043 43 COG3768 COG3768, Predicted membrane protein Function unknown 16272797 Common - hypothetical protein HI0857 25 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 30995350 Common phnA alkylphosphonate uptake protein HI0046 105 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 16272123 Common fabD acyl carrier protein S-malonyltransferase HI0156 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 16273441 Common sppA protease IV HI1541 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 16272674 Common - truncated suppressor of ftsI protein HI0733 63 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 16272972 Common - hypothetical protein HI1038 49 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 16272500 Common devB 6-phosphogluconolactonase HI0556 99 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 16273530 Common sapD peptide ABC transporter ATP-binding protein HI1641 249 COG4170 SapD, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 16273173 Common - hypothetical protein HI1254 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 16273398 Common - hypothetical protein HI1497 3 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 16273269 Common glgC glucose-1-phosphate adenylyltransferase HI1359 160 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 16273490 Common - hypothetical protein HI1600 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 30995469 Common - lipopolysaccharide biosynthesis protein HI1695 89 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 16273248 Common - hypothetical protein HI1338 46 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 16272733 Common rpsH 30S ribosomal protein S8 HI0792 238 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 16272621 Common glpE GlpE HI0679 79 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 16272553 Common fucA L-fuculose phosphate aldolase HI0611 156 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 16272666 Common narP nitrate/nitrite response regulator protein HI0726 220 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 16273260 Common cdd cytidine deaminase HI1350 36 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 16272903 Common - hypothetical protein HI0966 4 None None None 16273313 Common - hypothetical protein HI1405 19 COG3566 COG3566, Uncharacterized protein conserved in bacteria Function unknown 16272011 Common - ABC transporter ATP-binding protein HI0036 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 16272407 Common pyrR pyrimidine regulatory protein PyrR HI0459 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 16273015 Common - ABC transporter ATP-binding protein HI1087 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 16272421 Common hisA 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase HI0473 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 16272998 Common nrfC nitrite reductase Fe-S protein HI1067 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16272980 Common - hypothetical protein HI1048 30 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 16273535 Common - pyridoxine biosynthesis protein HI1647 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 16273423 Common - hypothetical protein HI1522.1 2 COG4416 Com, Mu-like prophage protein Com General function prediction only 16271984 Common fdhE formate dehydrogenase accessory protein FdhE HI0009 41 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 30995390 Common - hypothetical protein HI0633 37 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 16272031 Common uvrC excinuclease ABC subunit C HI0057 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 16273329 Common - integrase/recombinase HI1424 72 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 16272417 Common hisD histidinol dehydrogenase HI0469 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 16272549 Common aroE shikimate 5-dehydrogenase HI0607 217 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 16272555 Common fucK L-fuculokinase HI0613 175 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 16273352 Common bioD dithiobiotin synthetase HI1445 124 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 16273577 Common - sodium-dependent transporter HI1690 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 16273377 Common modD molybdenum transport protein ModD HI1473 200 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 16272026 Common - hypothetical protein HI0052 103 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 16272537 Common - hypothetical protein HI0594 51 COG1288 COG1288, Predicted membrane protein Function unknown 30995377 Common tdk thymidylate kinase HI0456 228 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 16271977 Common gapdH glyceraldehyde-3-phosphate dehydrogenase HI0001 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 16272134 Common - Na(+)-translocating NADH-quinone reductase subunit D HI0168 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 16272933 Pathogen tbp2 transferrin-binding protein 2 precursor HI0995 3 None None None 16273619 Common prfC peptide chain release factor 3 HI1735 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 16272945 Common - 3-hydroxyisobutyrate dehydrogenase HI1010 158 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 16272456 Pathogen hindIIR type II restriction endonuclease HI0512 1 None None None 16272007 Common pbp2 penicillin-binding protein 2 HI0032 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 16273626 Common recG ATP-dependent DNA helicase HI1740 215 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 30995421 Common nrfB cytochrome c-type protein NrfB HI1068 17 None None None 16273561 Common moaD molybdopterin synthase small subunit HI1674 62 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 16272759 Common galM aldose 1-epimerase HI0818 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 16272583 Common rplJ 50S ribosomal protein L10 HI0640 205 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 16271997 Common citF citrate lyase alpha chain HI0022 31 COG3051 CitF, Citrate lyase, alpha subunit Energy production and conversion 16272000 Common citC citrate lyase ligase HI0025 25 COG3053 CitC, Citrate lyase synthetase Energy production and conversion 16272483 Common ureC urease subunit alpha HI0539 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 16271990 Common lepB signal peptidase I HI0015 205 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 16272515 Common - peroxiredoxin hybrid Prx5 HI0572 115 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 16272259 Common - hypothetical protein HI0304 125 COG1678 COG1678, Putative transcriptional regulator Transcription 16272684 Common secB preprotein translocase subunit SecB HI0743 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 16272965 Common - 2,3-diketo-L-gulonate reductase HI1031 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 16272787 Common por periplasmic oxidoreductase HI0846 63 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 16273456 Common - glycerate dehydrogenase HI1556 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 16273333 Common purN phosphoribosylglycinamide formyltransferase HI1428 222 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 16272565 Common def peptide deformylase HI0622 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 16272592 Common rep ATP-dependent DNA helicase HI0649 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 16272161 Common mepA penicillin-insensitive murein endopeptidase HI0197 40 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 16272474 Common gcp O-sialoglycoprotein endopeptidase HI0530 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 16272676 Common - UDP-2,3-diacylglucosamine hydrolase HI0735 81 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 16272351 Common - methylated-DNA-protein-cysteine methyltransferase HI0402 210 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 16272726 Common rpmC 50S ribosomal protein L29 HI0785 86 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 16272273 Common yecO S-adenosyl-L-methionine-dependent methyltransferase HI0319 52 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 16272704 Common nadR nicotinamide-nucleotide adenylyltransferase HI0763 28 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 16273255 Common potC spermidine/putrescine ABC transporter membrane protein HI1345 180 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 16273060 Common murF UDP-MurNAc-pentapeptide synthetase HI1134 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 16273589 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase HI1702 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 16273292 Common pstC phosphate ABC transporter permease protein HI1382 227 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 16272348 Common icc cyclic 3',5'-adenosine monophosphate phosphodiesterase HI0399 73 COG1409 Icc, Predicted phosphohydrolases General function prediction only 16273081 Common cydC cysteine/glutathione ABC transporter membrane/ATP-binding component HI1156 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 16272781 Common - hypothetical protein HI0840 19 COG3082 COG3082, Uncharacterized protein conserved in bacteria Function unknown 16272521 Common - hypothetical protein HI0577 5 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 16273648 Common infC translation initiation factor IF-3 HI1318m 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 16273548 Common sucB 2-oxoglutarate dehydrogenase E2 component dihydrolipoamide succinyltransferase HI1661 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 16273600 Common ptsH phosphocarrier protein HPr HI1713 144 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 16272143 Common - hypothetical protein HI0178 4 None None None 16272304 Common - ABC transporter ATP-binding protein HI0354 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 16273160 Common - hypothetical protein HI1241 6 None None None 16273570 Common - Na(+)-translocating NADH-quinone reductase subunit E HI1683 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 16272305 Common - ABC transporter permease protein HI0355 190 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 16273006 Common pyrG CTP synthetase HI1077 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 16272921 Common - hypothetical protein HI0983 4 None None None 16272597 Common tagI DNA-3-methyladenine glycosidase I HI0654 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 16273406 Common - I protein HI1504 18 COG4388 COG4388, Mu-like prophage I protein General function prediction only 16273438 Common licB lic-1 operon protein HI1538 7 None None None 16273560 Common moaE molybdopterin converting factor subunit 2 HI1673 161 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 16272771 Common trpR Trp operon repressor HI0830 21 COG2973 TrpR, Trp operon repressor Transcription 16272222 Common hxuA heme-hemopexin utilization protein A HI0264 54 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 16272858 Common leuS leucyl-tRNA synthetase HI0921 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 30995438 Common - NifS HI1295 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 16273416 Common - monofunctional biosynthetic peptidoglycan transglycosylase HI1514 14 COG3941 COG3941, Mu-like prophage protein General function prediction only 16273115 Common ilvE branched-chain amino acid aminotransferase HI1193 189 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 30995459 Common - hypothetical protein HI1599 10 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 16273474 Common lpp 15 kDa peptidoglycan-associated lipoprotein HI1579 18 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 30995449 Common - hypothetical protein HI1434.2 15 COG3140 COG3140, Uncharacterized protein conserved in bacteria Function unknown 30995442 Common - hypothetical protein HI1315 19 COG4146 COG4146, Predicted symporter General function prediction only 16273270 Common glgA glycogen synthase HI1360 140 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 16272284 Common recO DNA repair protein RecO HI0332 102 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 16272462 Common deoD purine nucleoside phosphorylase HI0518 86 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 16273454 Common bioA adenosylmethionine--8-amino-7-oxononanoate transaminase HI1554 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 16272428 Common atpA F0F1 ATP synthase subunit alpha HI0481 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 16272928 Common iga1 immunoglobin A1 protease HI0990 50 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 16272045 Common ppnK inorganic polyphosphate/ATP-NAD kinase HI0072 238 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 16273520 Common - hypothetical protein HI1631 5 None None None 16272038 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine-pyrophosphokinase HI0064 201 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 16272504 Common - serine protease HI0561 42 COG1297 COG1297, Predicted membrane protein Function unknown 16272605 Common - ABC transporter ATP-binding protein HI0664 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 16272199 Common secF preprotein translocase subunit SecF HI0239 207 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 16273527 Common sapA peptide ABC transporter periplasmic-binding protein HI1638 182 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 30995399 Common dat1 hypothetical protein HI0755 62 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 16272822 Common - hypothetical protein HI0882 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 16272528 Common - hydrolase HI0584 173 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 16273542 Common - antigen HI1655 42 COG3107 LppC, Putative lipoprotein General function prediction only 16273095 Common trpG para-aminobenzoate synthase component II HI1171 233 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 16272463 Common - transport protein HI0519 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 16273186 Pathogen - hypothetical protein HI1269 1 None None None 16273028 Common cysZ putative sulfate transport protein CysZ HI1102 44 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 16273170 Common vapA virulence-associated protein A HI1251 75 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 16272762 Common galR galactose operon repressor HI0821 126 COG1609 PurR, Transcriptional regulators Transcription 16272668 Common cyaY frataxin-like protein HI0727.1 41 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 16272436 Common - hypothetical protein HI0488 177 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 16272900 Common ribF bifunctional riboflavin kinase/FMN adenylyltransferase HI0963 211 COG0196 RibF, FAD synthase Coenzyme metabolism 16272878 Common - hypothetical protein HI0941 4 None None None 16273179 Common folC folylpolyglutamate synthase/dihydrofolate synthase HI1261 217 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 16272488 Common rplI 50S ribosomal protein L9 HI0544 209 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 16273357 Common - dsDNA-mimic protein HI1450 18 COG3099 COG3099, Uncharacterized protein conserved in bacteria Function unknown 16272930 Common dnaN DNA polymerase III subunit beta HI0992 214 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 16272856 Common cdsA CDP-diglyceride synthetase HI0919 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 16273226 Common nlpC lipoprotein HI1314 134 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 16272117 Common - hypothetical protein HI0149 9 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 30995427 Common - thioredoxin domain-containing protein HI1159m 129 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 16272896 Common rumB 23S rRNA metyluridine methyltransferase HI0958 147 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 16272111 Common - N-acetylmannosamine kinase HI0144 152 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 16272816 Common ndk nucleoside diphosphate kinase HI0876 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 16272626 Common glpB anaerobic glycerol-3-phosphate dehydrogenase subunit B HI0684 32 COG3075 GlpB, Anaerobic glycerol-3-phosphate dehydrogenase Amino acid transport and metabolism 16272843 Common - hypothetical protein HI0906 216 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 16273646 Common gcvA transcription activator HI1194m 182 COG0583 LysR, Transcriptional regulator Transcription 16272788 Common - hypothetical protein HI0847 23 COG3085 COG3085, Uncharacterized protein conserved in bacteria Function unknown 16272163 Common msbB lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase HI0199 94 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 16272349 Common - hypothetical protein HI0400 16 COG3691 COG3691, Uncharacterized protein conserved in bacteria Function unknown 16273063 Common ftsW cell division protein HI1137 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 16272364 Common - hydroxyethylthiazole kinase HI0415 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 16272613 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase HI0671 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 16272393 Common secG preprotein translocase subunit SecG HI0445 23 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 16272693 Common purL phosphoribosylformylglycinamidine synthase HI0752 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 16273479 Common ilvI acetolactate synthase 3 catalytic subunit HI1585 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 16272114 Common - hypothetical protein HI0147 123 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 16272024 Common kdgK 2-dehydro-3-deoxygluconokinase HI0049 148 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 16273284 Common kicA condesin subunit E HI1373 20 COG3095 MukE, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 16272098 Common afuA ferric ABC transporter protein HI0131 106 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 16273030 Common - transporter protein HI1104 161 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16272055 Common - hypothetical protein HI0081 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 16273422 Pathogen - hypothetical protein HI1522 3 None None None 16272866 Common - hypothetical protein HI0929 54 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 16272863 Common - hypothetical protein HI0926 7 COG4545 COG4545, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 30995366 Common lnt apolipoprotein N-acyltransferase HI0302 166 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 16272388 Common ponA penicillin-binding protein 1A HI0440 201 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 16273037 Common xylA xylose isomerase HI1112 69 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 16272424 Common tyrP tyrosine-specific transport protein HI0477 33 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 16273099 Common artM arginine transporter permease subunit ArtM HI1177 164 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 16273634 Common aphA acid phosphatase/phosphotransferase HI0495m 12 COG3700 AphA, Acid phosphatase (class B) General function prediction only 16273258 Common pepT peptidase T HI1348 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 16273043 Common - GTPase EngB HI1118 179 COG0218 COG0218, Predicted GTPase General function prediction only 161350019 Common pgi glucose-6-phosphate isomerase HI1576 197 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 16272336 Common - hypothetical protein HI0388 188 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 16273246 Common folP-1 dihydropteroate synthase HI1336 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 16272974 Common - modification methylase HI1041 111 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 16273656 Common - hypothetical protein HI1729m 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 16273158 Common proA gamma-glutamyl phosphate reductase HI1239 188 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 16272330 Common tolB translocation protein TolB HI0382 168 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 30995450 Common - hypothetical protein HI1456 11 None None None 161350027 Common - primosomal replication protein N HI0546 24 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 16273566 Common yrbI phosphatase HI1679 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 30995352 Common grpE heat shock protein HI0071 218 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 30995467 Common kgd alpha-ketoglutarate decarboxylase HI1662 149 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 16272993 Common fabZ (3R)-hydroxymyristol (acyl carrier protein) dehydrase HI1062 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 16273146 Common uraA uracil permease HI1227 123 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 16272718 Common rplC 50S ribosomal protein L3 HI0777 239 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 16272711 Common ftsX cell division protein FtsX HI0770 99 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 30995413 Common rpsT 30S ribosomal protein S20 HI0965 159 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 16273558 Common - hypothetical protein HI1671 53 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 16272746 Common - hypothetical protein HI0804 26 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 16273241 Common dacB D-alanyl-D-alanine carboxypeptidase/endopeptidase HI1330 98 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 16272264 Common xerD site-specific tyrosine recombinase XerD HI0309 225 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 16272914 Common - hypothetical protein HI0976.1 43 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 16273671 Common mltA membrane-bound lytic murein transglycosylase HI0117 92 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 16273203 Common truB tRNA pseudouridine synthase B HI1289 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 16273460 Common - hypothetical protein HI1560 2 COG1714 COG1714, Predicted membrane protein/domain Function unknown 16272275 Common - virulence-associated protein C HI0322 53 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 16273166 Common uvrB excinuclease ABC subunit B HI1247 234 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 16272905 Common menB naphthoate synthase HI0968 180 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 16273396 Pathogen - hypothetical protein HI1495 1 None None None 30995370 Common nifS cysteine desulfurase HI0378 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 16272195 Common - hypothetical protein HI0232 99 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 16272129 Common - lipoprotein HI0162 18 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 16273275 Common topA DNA topoisomerase I HI1365 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 16273086 Common - CrcB HI1162 44 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 16273077 Common pmbA PmbA HI1152 157 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 16272839 Common - dinucleoside polyphosphate hydrolase HI0901 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 16273504 Common pepN aminopeptidase N HI1614 161 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 16272793 Common dppA heme-binding lipoprotein HI0853 213 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 16273346 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase HI1439 226 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 161350020 Common - universal stress protein UspE HI1426 52 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 30995385 Common infA translation initiation factor IF-1 HI0548 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 16272186 Common - hypothetical protein HI0223 94 COG2962 RarD, Predicted permeases General function prediction only 16273500 Common tyrS tyrosyl-tRNA synthetase HI1610 244 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16273467 Common - hypothetical protein HI1571 7 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 16272212 Common bcp thioredoxin-dependent thiol peroxidase HI0254 213 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 16272313 Common - hypothetical protein HI0365 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 16273142 Common - hypothetical protein HI1223 61 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 16272125 Common rpmF 50S ribosomal protein L32 HI0158 66 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 16272678 Common - acetohydroxy acid synthase II HI0737 220 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 16272656 Common secE preprotein translocase subunit SecE HI0716 66 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 16273413 Common - sheath protein gpL HI1511 21 COG4386 COG4386, Mu-like prophage tail sheath protein gpL General function prediction only 16272819 Common rpmA 50S ribosomal protein L27 HI0879 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 16271995 Common - transport protein HI0020 100 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 16272801 Common vacB virulence-associated protein HI0861 200 COG0557 VacB, Exoribonuclease R Transcription 16272943 Common - hypothetical protein HI1008 91 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 16272296 Common napG quinol dehydrogenase periplasmic component HI0345 58 COG1145 NapF, Ferredoxin Energy production and conversion 16273369 Common folP-2 dihydropteroate synthase HI1464 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 16273107 Common dppD dipeptide transporter ATP-binding subunit HI1185 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 16273306 Common holC DNA polymerase III subunit chi HI1397 54 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 16272302 Common galE UDP-glucose 4-epimerase HI0351 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 30995397 Common yhxB phosphomannomutase HI0740 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 16273563 Common moaA molybdenum cofactor biosynthesis protein A HI1676 203 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 16273118 Common - hypothetical protein HI1198 226 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 16272530 Common - hypothetical protein HI0586 7 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 16272611 Common mioC flavodoxin HI0669 71 COG0716 FldA, Flavodoxins Energy production and conversion 16272243 Common sdaA L-serine deaminase HI0288 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 16273198 Common infB translation initiation factor IF-2 HI1284 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 16273381 Common ner DNA-binding protein HI1477 22 COG3423 Nlp, Predicted transcriptional regulator Transcription 16272563 Common metN DL-methionine transporter ATP-binding subunit HI0621 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 16272810 Pathogen - hypothetical protein HI0870 1 None None None 16272590 Common - transport protein HI0647 116 COG1285 SapB, Uncharacterized membrane protein Function unknown 16272145 Common - formate acetyltransferase 1-like protein HI0180 58 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 16272472 Common tyrP tyrosine-specific transport protein HI0528 33 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 16273140 Common himD integration host factor beta-subunit HI1221 204 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 16272043 Common glnE glutamate-ammonia-ligase adenylyltransferase HI0069 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 16272728 Common - hypothetical protein HI0787 5 None None None 16271989 Common rnc ribonuclease III HI0014 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 16272540 Common - hypothetical protein HI0597 109 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 16272062 Common thrB homoserine kinase HI0088 129 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 16272594 Common coaD phosphopantetheine adenylyltransferase HI0651 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 16273359 Common purL phosphoribosylformylglycinamidine synthase HI1453 71 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 16273512 Common - hypothetical protein HI1624 9 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 16273253 Common - ABC transporter ATP-binding protein HI1342 239 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 16272976 Common - twin-argninine leader-binding protein DmsD HI1044 27 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 30995403 Common galK galactokinase HI0819 83 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 30995473 Common - transposase HI1721 146 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 16273375 Common - iron chelatin ABC transporter permease protein HI1471 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 16273425 Common - molybdate-binding periplasmic protein HI1525 56 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 16272419 Common hisB imidazole glycerol-phosphate dehydratase/histidinol phosphatase HI0471 217 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 30995380 Common - hypothetical protein HI0500 110 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 16271982 Common fdxH formate dehydrogenase beta subunit HI0007 160 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16272368 Common - protease HI0419 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 16273354 Common folE GTP cyclohydrolase I HI1447 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 16272547 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase HI0605 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 16272539 Common arcB ornithine carbamoyltransferase HI0596 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 16272132 Common nqrB Na(+)-translocating NADH-quinone reductase subunit B HI0166 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 16273617 Common rnb exoribonuclease II HI1733 192 COG4776 Rnb, Exoribonuclease II Transcription 16272735 Common rplR 50S ribosomal protein L18 HI0794 207 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 16272940 Common - hypothetical protein HI1005 63 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 16272517 Common fkpA FKBP-type peptidyl-prolyl cis-trans isomerase HI0574 139 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 16272323 Common hscB co-chaperone HscB HI0375 55 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 16272618 Common xerC site-specific tyrosine recombinase XerC HI0676 225 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 16273484 Common - recombination factor protein RarA HI1590 241 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 16271979 Common - haloacid dehalogenase-like protein HI0003 129 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 16272016 Common xthA exonuclease III HI0041 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 16272599 Common - hypothetical protein HI0656 211 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 16273100 Common artQ arginine transporter permease subunit ArtQ HI1178 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 16273308 Common - hypothetical protein HI1399 18 None None None 16272935 Common rnpA ribonuclease P HI0999 73 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 16273350 Common rplM 50S ribosomal protein L13 HI1443 237 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 30995375 Common - DNA-binding protein HU-alpha HI0430 211 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 16273057 Common ftsL cell division protein HI1131 21 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 16272558 Common hepA ATP-dependent helicase HepA HI0616 140 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 16272585 Common glmU bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase HI0642 231 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 16273609 Common - hypothetical protein HI1723 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 16273097 Common sprT hypothetical protein HI1173 26 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 16273070 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase HI1144 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 16273317 Common - terminase large subunit-like protein HI1410 27 COG1783 XtmB, Phage terminase large subunit General function prediction only 30995444 Common potA putrescine/spermidine ABC transporter ATPase protein HI1347 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 16272040 Common - N-acetylmuramoyl-L-alanine amidase HI0066 175 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 16273687 Common tatA Sec-independent protein secretion pathway component TatA HI0187a 44 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 16273326 Common - hypothetical protein HI1420 39 COG3636 COG3636, Predicted transcriptional regulator Transcription 16272253 Common - protein transport protein HI0298 209 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 16273559 Common - hypothetical protein HI1672 57 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 16273452 Common - hypothetical protein HI1552 14 COG2830 COG2830, Uncharacterized protein conserved in bacteria Function unknown 16273032 Common xylR xylose operon regluatory protein HI1106 82 COG1609 PurR, Transcriptional regulators Transcription 16273088 Common ompA outer membrane protein P5 HI1164 144 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 16273132 Common dsbC thiol-disulfide interchange protein HI1213 59 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 16272824 Common arcA DNA-binding response regulator in two-component regulatory system with ArcB or CpxA HI0884 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16273262 Common putP sodium/proline symporter HI1352 170 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 16273123 Common pta phosphate acetyltransferase HI1203 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 16273004 Common cydB cytochrome D ubiquinol oxidase subunit II HI1075 154 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 16273151 Common aceF dihydrolipoamide acetyltransferase HI1232 199 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 16272876 Common - hypothetical protein HI0939 6 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 16272081 Common - hypothetical protein HI0107 218 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 16272837 Common folA dihydrofolate reductase HI0899 149 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 16273584 Common - lipopolysaccharide biosynthesis protein HI1697 14 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 16273217 Common thiL thiamin-monophosphate kinase HI1305 198 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 16273210 Common - hypothetical protein HI1297 25 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 16272459 Common rpoB DNA-directed RNA polymerase subunit beta HI0515 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 16272153 Common gdhA glutamate dehydrogenase HI0189 166 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 16273404 Common - hypothetical protein HI1502 28 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 16273459 Common hemK HemK HI1559 218 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 16272778 Common cpxR response regulator HI0837 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16272635 Common hel lipoprotein E HI0693 26 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 16272982 Common merP mercuric ion scavenger protein HI1050 5 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 16272346 Common xseA exodeoxyribonuclease VII large subunit HI0397 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 16272724 Common rpsC 30S ribosomal protein S3 HI0783 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 16273172 Common - hypothetical protein HI1253 21 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 16273443 Common - hypothetical protein HI1543 14 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 16272215 Common - sigma 54 modulation-like protein HI0257 65 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 16272783 Common - hypothetical protein HI0842 52 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 16272686 Common ansB L-asparaginase II HI0745 140 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 16273552 Common - hypothetical protein HI1665 31 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 16273219 Common - hypothetical protein HI1307 103 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 16272309 Common yfeC iron (chelated) ABC transporter permease protein HI0360 186 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 16272502 Common cysQ sulfite synthesis pathway protein HI0559 150 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 16272286 Common relA GTP pyrophosphokinase HI0334 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 16273079 Common - proton glutamate symport protein HI1154 151 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 16272773 Common frdD fumarate reductase subunit D HI0832 21 COG3080 FrdD, Fumarate reductase subunit D Energy production and conversion 16272748 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase HI0807 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 16272405 Common - hypothetical protein HI0457 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 16272381 Common - predicted gluconate transport-associated protein HI0433 59 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 16273628 Common rpoZ DNA-directed RNA polymerase subunit omega HI1742 109 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 16272926 Common leuC isopropylmalate isomerase large subunit HI0988 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 16272991 Common lpxB lipid-A-disaccharide synthase HI1060 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 16273621 Common - hypothetical protein HI1737 18 COG1687 AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) Amino acid transport and metabolism 16272224 Common - hypothetical protein HI0266 170 COG0344 COG0344, Predicted membrane protein Function unknown 16272648 Common selA selenocysteine synthase HI0708 71 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 16272271 Common aspS aspartyl-tRNA synthetase HI0317 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16272538 Common arcC carbamate kinase HI0595 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 16272312 Common - penicillin-binding protein 7 HI0364 141 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 16271981 Common fdhD formate dehydrogenase accessory protein HI0005 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 16272603 Common - hypothetical protein HI0660 27 COG4679 COG4679, Phage-related protein Function unknown 161350022 Common rpsB 30S ribosomal protein S2 HI0913 220 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 16273604 Common - hypothetical protein HI1718 7 None None None 16273498 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase HI1608 192 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 16273465 Common - G protein HI1568 20 COG5005 COG5005, Mu-like prophage protein gpG General function prediction only 16272768 Common - hypothetical protein HI0827 117 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 16273534 Common fbp fructose-1,6-bisphosphatase HI1645 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 16272184 Common - inosine-5'-monophosphate dehydrogenase-like protein HI0221.1 222 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 16273244 Common rrmJ 23S rRNA methyltransferase J HI1334 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 16272644 Common lppB lipoprotein B HI0703 50 COG1238 COG1238, Predicted membrane protein Function unknown 16272761 Common galT galactose-1-phosphate uridylyltransferase HI0820 80 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 16272510 Common gyrB DNA gyrase subunit B HI0567 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 16272108 Common nagB glucosamine-6-phosphate deaminase HI0141 81 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 16273280 Common mopI molybdenum-pterin binding protein HI1370 68 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 30995354 Common hitA iron(III) ABC transporter periplasmic-binding protein HI0097 126 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 16272956 Common bioB biotin synthetase HI1022 175 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 16272358 Common - hypothetical protein HI0409 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 16273590 Common - hypothetical protein HI1703 108 COG0795 COG0795, Predicted permeases General function prediction only 30995369 Common iscU scaffold protein HI0377 153 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 16273038 Common - xylulose kinase HI1113 176 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 16272290 Common - hypothetical protein HI0338 37 COG0628 PerM, Predicted permease General function prediction only 16273583 Common - lipopolysaccharide biosynthesis protein HI1696 118 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 16272794 Common - hypothetical protein HI0854 15 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 16272713 Common atoE short chain fatty acids transporter HI0772 39 COG2031 AtoE, Short chain fatty acids transporter Lipid metabolism 16273021 Common ccmE cytochrome c-type biogenesis protein CcmE HI1093 92 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 16272632 Common glpF glycerol uptake facilitator protein HI0690 134 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 16272498 Common - hypothetical protein HI0554 16 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16273567 Common - hypothetical protein HI1680 44 COG1289 COG1289, Predicted membrane protein Function unknown 30995356 Common - hypothetical protein HI0105 126 COG0327 COG0327, Uncharacterized conserved protein Function unknown 16273178 Common accD acetyl-CoA carboxylase subunit beta HI1260 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 16272834 Common ftsN cell division protein HI0896 20 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 16272577 Common - tRNA-dihydrouridine synthase A HI0634 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 16272197 Common - hypothetical protein HI0235 20 COG3036 COG3036, Uncharacterized protein conserved in bacteria Function unknown 16273316 Common - hypothetical protein HI1409 20 COG3567 COG3567, Uncharacterized protein conserved in bacteria Function unknown 16272219 Common - lipopolysaccharide biosynthesis protein HI0261 101 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 16273394 Common - hypothetical protein HI1493 3 None None None 16272699 Common rpmE 50S ribosomal protein L31 HI0758 201 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 16272263 Common - putative 3-phenylpropionic acid transporter HI0308 75 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16272087 Common hemR hemin receptor HI0113 73 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 16272203 Common - hypothetical protein HI0243 18 None None None 30995374 Common nhaB sodium/proton antiporter HI0427 29 COG3067 NhaB, Na+/H+ antiporter Inorganic ion transport and metabolism 16272854 Common - protective surface antigen D15 HI0917 161 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 16272669 Common recQ ATP-dependent DNA helicase HI0728 234 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 16273291 Common pstA phosphate ABC transporter permease protein HI1381 222 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 16272239 Common menD 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase HI0283 79 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 16272209 Common - TonB HI0251 24 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 16272229 Common djlA Dna-J like membrane chaperone protein HI0271 74 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 16273576 Common nth endonuclease III HI1689 238 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 16272707 Common yibK rRNA methylase HI0766 158 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 16273041 Common deoC deoxyribose-phosphate aldolase HI1116 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 16272220 Common - heme-hemopexin utilization protein C HI0262 97 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 16272319 Common - hypothetical protein HI0371 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 16272333 Common tolQ colicin transport protein HI0385 146 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 16272888 Common rpmG 50S ribosomal protein L33 HI0950 137 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 16273330 Common fnr fumarate/nitrate reduction transcriptional regulator HI1425 162 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 16272104 Common dnaQ DNA polymerase III subunit epsilon HI0137 187 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 30995452 Common - hypothetical protein HI1462.1 6 None None None 30995381 Common menA 1,4-dihydroxy-2-naphthoate octaprenyltransferase HI0509 84 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 30995411 Common radC DNA repair protein RadC HI0952 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 30995464 Common - hypothetical protein HI1648 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 16273632 Common tatB sec-independent translocase HI0187b 23 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 16273124 Common ackA acetate kinase HI1204 161 COG0282 ackA, Acetate kinase Energy production and conversion 16272370 Common srmB ATP-dependent RNA helicase SrmB HI0422 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 16272658 Common vacJ lipoprotein HI0718 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 16272893 Common slmA nucleoid occlusion protein HI0955 72 COG1309 AcrR, Transcriptional regulator Transcription 16273616 Common - hypothetical protein HI1731 99 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 16273024 Pathogen - hypothetical protein HI1098 1 None None None 16273031 Common rfaF ADP-heptose-LPS heptosyltransferase II HI1105 110 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 16272210 Common exbD biopolymer transport protein HI0252 57 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 16273058 Common ftsI penicillin-binding protein 3 HI1132 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 16272052 Common cysS cysteinyl-tRNA synthetase HI0078 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16272466 Common - hypothetical protein HI0522 28 COG2364 COG2364, Predicted membrane protein Function unknown 16272573 Common rseB periplasmic negative regulator of sigmaE HI0630 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 16272518 Common - hypothetical protein HI0575 49 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 16273573 Common rnfD electron transport complex protein RnfD HI1686 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 16272366 Common thiE thiamine-phosphate pyrophosphorylase HI0417 203 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 16272642 Common truD tRNA pseudouridine synthase D HI0701 86 COG0585 COG0585, Uncharacterized conserved protein Function unknown 16273169 Common - hypothetical protein HI1250 42 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 16273298 Common - hypothetical protein HI1388.1 11 None None None 16273383 Pathogen - hypothetical protein HI1479 1 None None None 16272435 Common - hypothetical protein HI0487 7 None None None 16272692 Common tpx thiol peroxidase HI0751 94 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 16272392 Common topB DNA topoisomerase III HI0444 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 16272802 Common - hypothetical protein HI0862 74 COG1738 COG1738, Uncharacterized conserved protein Function unknown 30995425 Common - hypothetical protein HI1146 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 16272200 Common secD preprotein translocase subunit SecD HI0240 222 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 16272382 Common comF competence protein F HI0434 168 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 16272389 Common - hypothetical protein HI0441 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 30995398 Common lexA LexA repressor HI0749 174 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 16272486 Common groES co-chaperonin GroES HI0542 213 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 16272230 Common pyrE orotate phosphoribosyltransferase HI0272 127 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 30995419 Common - type III restriction-modification system endonuclease-like protein HI1055 9 COG3421 COG3421, Uncharacterized protein conserved in bacteria Function unknown 16272112 Common - N-acetylmannosamine-6-phosphate 2-epimerase HI0145 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 16272628 Common glpT glycerol-3-phosphatase transporter HI0686 90 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 16273223 Common pheS phenylalanyl-tRNA synthetase subunit alpha HI1311 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 16272080 Common ffh signal recognition particle protein HI0106 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 16273049 Common oppA oligopeptide ABC transporter periplasmic-binding protein HI1124 191 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 30995360 Common ribA GTP cyclohydrolase II HI0212 188 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 16273445 Common - sodium/dicarboxylate symporter protein HI1545 140 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 16273259 Common - hypothetical protein HI1349 127 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 16273478 Common ilvH acetolactate synthase 3 regulatory subunit HI1584 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 30995445 Common kicB condesin subunit F HI1372 20 COG3006 MukF, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 16272372 Common - rRNA methylase HI0424 97 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 16273402 Common - hypothetical protein HI1500 24 COG4373 COG4373, Mu-like prophage FluMu protein gp28 General function prediction only 16272227 Common rpoH RNA polymerase factor sigma-32 HI0269 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 16272384 Pathogen comD competence protein D HI0436 1 None None None 16272327 Common - hypothetical protein HI0379 173 COG1959 COG1959, Predicted transcriptional regulator Transcription 16272281 Common - hypothetical protein HI0329 127 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 16272344 Common - hypothetical protein HI0395 61 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 16273139 Common rpsA 30S ribosomal protein S1 HI1220 216 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 16272775 Common frdB fumarate reductase iron-sulfur subunit HI0834 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 16273571 Common - electron transport complex protein RnfB HI1684 111 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 16273225 Common himA integration host factor alpha-subunit HI1313 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 16272014 Common mreD rod shape-determining protein HI0039 35 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 16272609 Common glpX fructose 1,6-bisphosphatase II HI0667 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 16273623 Common metR transcriptional activator HI1739 190 COG0583 LysR, Transcriptional regulator Transcription 16272827 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase HI0887 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 16272308 Common yfeD iron (chelated) ABC transporter permease protein HI0359 187 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 16272664 Common - hypothetical protein HI0724 7 COG3078 COG3078, Uncharacterized protein conserved in bacteria Function unknown 16273555 Common prc carboxy-terminal protease HI1668 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 16272479 Common ureH urease accessory protein HI0535 34 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 16273111 Common - hypothetical protein HI1189 173 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 16272910 Common - hypothetical protein HI0973 5 None None None 16273588 Common - hypothetical protein HI1701 61 COG1434 COG1434, Uncharacterized conserved protein Function unknown 16272688 Common ndh NADH dehydrogenase HI0747 193 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 16273211 Common - hypothetical protein HI1298 81 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 16272532 Common - allantoate amidohydrolase HI0588 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 16272317 Common hisS histidyl-tRNA synthetase HI0369 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16272288 Common mogA molybdenum cofactor biosynthesis protein HI0336 185 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 16272082 Common - hypothetical protein HI0108 41 COG3610 COG3610, Uncharacterized conserved protein Function unknown 16272522 Common tuf elongation factor Tu HI0578 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 16272873 Common - cytochrome C-type biogenesis HI0936 137 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 30995435 Common mrp putative ATPase HI1277 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 16272649 Common selB selenocysteine-specific elongation factor HI0709 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 16272158 Common menE O-succinylbenzoic acid--CoA ligase HI0194 201 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16273340 Common cspD cold shock-like protein HI1434.1 174 COG1278 CspC, Cold shock proteins Transcription 16272832 Common - lipoprotein HI0894 169 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 16272600 Common - hypothetical protein HI0656.1 125 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 16273434 Common - hypothetical protein HI1534 65 COG4121 COG4121, Uncharacterized conserved protein Function unknown 16273264 Common glnS glutaminyl-tRNA synthetase HI1354 241 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 16272484 Common ureB urease subunit beta HI0540 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 16273175 Common - hypothetical protein HI1256 23 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 16272067 Common - hypothetical protein HI0093 43 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 16271988 Common era GTP-binding protein Era HI0013 238 COG1159 Era, GTPase General function prediction only 16272638 Common - hypothetical protein HI0696 101 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 16273494 Common - phosphate permease HI1604 174 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 16272767 Common - intracellular septation protein A HI0826 89 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 16272700 Common mutY A/G-specific adenine glycosylase HI0759 230 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 16272139 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase HI0174 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 16272036 Common dksA dnaK suppressor protein HI0062 143 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 16273091 Common serC phosphoserine aminotransferase HI1167 117 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 16272913 Common - hypothetical protein HI0976 5 None None None 16273056 Common mraW S-adenosyl-methyltransferase MraW HI1130 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 16272966 Common - transcriptional regulator HI1032 113 COG1414 IclR, Transcriptional regulator Transcription 16272978 Common dmsB anaerobic dimethyl sulfoxide reductase chain B HI1046 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 16272412 Common rpiA ribose-5-phosphate isomerase A HI0464 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 16273205 Common queF 7-cyano-7-deazaguanine reductase HI1291 86 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 16273011 Common - anti-sigma factor B antagonist HI1083 8 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 16272937 Common yidC putative inner membrane protein translocase component YidC HI1001 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 16272354 Common - pyridoxamine kinase HI0405 69 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 16272738 Common rplO 50S ribosomal protein L15 HI0797 87 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 16272951 Common - hypothetical protein HI1016 13 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 16273595 Common ygiX transcriptional regulatory protein HI1708 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16272073 Common hitC iron(III) ABC transporter ATP-binding protein HI0099 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 16272961 Common lyx L-xylulose kinase HI1027 179 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 16273373 Common - hypothetical protein HI1469 3 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 16273250 Common - hypothetical protein HI1340 108 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 16272508 Common gph phosphoglycolate phosphatase HI0565 201 COG0546 Gph, Predicted phosphatases General function prediction only 16273565 Common kpsF KpsF HI1678 162 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 16272737 Common rpmD 50S ribosomal protein L30 HI0796 146 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 16273602 Common - oligoribonuclease HI1715 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 16273148 Common dnaX DNA polymerase III subunits gamma and tau HI1229 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 16273304 Common - hypothetical protein HI1394 16 COG3097 COG3097, Uncharacterized protein conserved in bacteria Function unknown 16273447 Common aroG phospho-2-dehydro-3-heoxyheptonate aldolase HI1547 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 16272321 Common hscA chaperone protein HscA HI0373 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 16272138 Common - hypothetical protein HI0173 19 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 16273496 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase HI1606 195 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 16273515 Common - hypothetical protein HI1626 10 None None None 30995475 Common hemH phosphoribosylaminoimidazole-succinocarboxamide synthase HI1726 199 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 16272377 Common glmS D-fructose-6-phosphate amidotransferase HI0429 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 16273514 Common - hypothetical protein HI1625 85 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 16272170 Common aroK shikimate kinase HI0207 202 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 16273154 Common - hypothetical protein HI1235 4 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 16272478 Common aspA aspartate ammonia-lyase HI0534 220 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 16272255 Common ampD N-acetyl-anhydromuranmyl-L-alanine amidase HI0300 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 16272949 Common - hypothetical protein HI1014 212 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16272842 Common thyA thymidylate synthase HI0905 136 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 16272165 Common trmD tRNA (guanine-N(1)-)-methyltransferase HI0202 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 16273361 Common msrA bifunctional methionine sulfoxide reductase A/B protein HI1455 206 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 16273482 Common purU formyltetrahydrofolate deformylase HI1588 220 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 16272612 Common - D-tyrosyl-tRNA deacylase HI0670 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 16272750 Common pckA phosphoenolpyruvate carboxykinase HI0809 97 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 30995349 Common mreB rod shape-determining protein HI0037 234 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 16272004 Common dacA penicillin-binding protein 5 HI0029 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 16272754 Common csrA carbon storage regulator HI0813 84 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 16273337 Common trpA tryptophan synthase subunit alpha HI1432 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 16272971 Common - hypothetical protein HI1037 73 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 16272551 Common folD methylenetetrahydrofolate dehydrogenase/methenyltetrahydrofolate cyclohydrolase HI0609 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 16272723 Common rplV 50S ribosomal protein L22 HI0782 218 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 16273389 Pathogen - hypothetical protein HI1486 1 None None None 16273085 Common - hypothetical protein HI1161 98 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 16272064 Common - hypothetical protein HI0090 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 16272449 Common rbsK ribokinase HI0505 184 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 16271993 Common ung uracil-DNA glycosylase HI0018 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 16272730 Common rplX 50S ribosomal protein L24 HI0789 208 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 16272452 Common menG ribonuclease activity regulator protein RraA HI0508 80 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 16272808 Common - hypothetical protein HI0868 183 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 16272292 Common trmB tRNA (guanine-N(7))-methyltransferase HI0340 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 16272561 Common glpR glycerol-3-phosphate regulon repressor HI0619 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16272575 Common tuf elongation factor Tu HI0632 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 16272870 Common - hypothetical protein HI0933 139 COG2081 COG2081, Predicted flavoproteins General function prediction only 16272554 Common fucU fucose operon protein HI0612 31 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 16272093 Common pgsA phosphatidylglycerophosphate synthase HI0123 201 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 16273129 Common argR arginine repressor HI1209 78 COG1438 ArgR, Arginine repressor Transcription 16272715 Common - acetyl-CoA:acetoacetyl-CoA transferase subunit alpha HI0774 99 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 16272671 Common - organic solvent tolerance protein HI0730 118 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 16273334 Common purM phosphoribosylaminoimidazole synthetase HI1429 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 16272566 Common fmt methionyl-tRNA formyltransferase HI0623 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 16273554 Common - hypothetical protein HI1667 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 16272884 Common - L-24-diaminobutyrate decarboxylase HI0946.1 111 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 16272491 Common rpsF 30S ribosomal protein S6 HI0547 197 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 16272496 Common - hypothetical protein HI0552 6 None None None 16272886 Common - hypothetical protein HI0948 22 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 16272429 Common atpH F0F1 ATP synthase subunit delta HI0482 148 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 16272299 Common napC cytochrome C-type protein HI0348 52 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 16272261 Common rdgC recombination associated protein HI0306 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 16272356 Common - hypothetical protein HI0407 182 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 16272740 Common rpmJ 50S ribosomal protein L36 HI0798.1 137 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 16272527 Common cpdB bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein HI0583 126 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 16273242 Common greA transcription elongation factor GreA HI1331 204 COG0782 GreA, Transcription elongation factor Transcription 16273296 Common trpE anthranilate synthase component I HI1387 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 16272823 Common - amino acid carrier protein HI0883 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 16272089 Common znuA high-affinity zinc transporter periplasmic component HI0119 140 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 16273230 Common rplT 50S ribosomal protein L20 HI1320 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 16273392 Common - hypothetical protein HI1489 5 None None None 30995392 Common yecK cytochrome C-like protein HI0644 56 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 16272268 Common ruvC Holliday junction resolvase HI0314 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 16273276 Common acpD acyl carrier protein phosphodiesterase HI1366 99 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 16272310 Common yfeB iron (chelated) transporter ATP-binding protein HI0361 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 16273349 Common rpsI 30S ribosomal protein S9 HI1442 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 16273461 Common prfA peptide chain release factor 1 HI1561 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 16272339 Common rnd ribonuclease D HI0390 124 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 16273440 Common licD lic-1 operon protein HI1540 16 COG3475 COG3475, LPS biosynthesis protein Cell envelope biogenesis, outer membrane 16273578 Common modC molybdate transporter ATP-binding protein HI1691 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 16272126 Common - hypothetical protein HI0159 56 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 16273463 Common - hypothetical protein HI1563 31 COG3101 COG3101, Uncharacterized protein conserved in bacteria Function unknown 16272455 Common - potassium-tellurite ethidium and proflavin transporter HI0511 46 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 16273309 Common - hypothetical protein HI1400 133 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 16272360 Common hfq RNA-binding protein Hfq HI0411 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 16272373 Common pssA phosphatidylserine synthase HI0425 31 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 16272571 Common rpoE RNA polymerase sigma factor RpoE HI0628 175 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 16272433 Common - F0F1 ATP synthase subunit I HI0485.1 3 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 16272182 Common birA biotin--protein ligase HI0220.1 228 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 16273539 Common - hypothetical protein HI1651 3 None None None 16272403 Common holB DNA polymerase III subunit delta' HI0455 212 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 16273221 Common - hypothetical protein HI1309 41 COG0633 Fdx, Ferredoxin Energy production and conversion 16272232 Common gltX glutamyl-tRNA synthetase HI0274 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 30995401 Common - transcriptional regulator HI0775 157 COG0583 LysR, Transcriptional regulator Transcription 30995379 Common potD spermidine/putrescine ABC transporter periplasmic-binding protein HI0498 144 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 16272106 Common ompP2 outer membrane protein P2 HI0139 7 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 16273532 Common - hypothetical protein HI1643 116 COG2855 COG2855, Predicted membrane protein Function unknown 16272997 Common nrfD nitrite reductase transmembrane protein HI1066 29 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 16272646 Common - lipoprotein HI0706 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 16272050 Common tesB acyl-CoA thioesterase II HI0076 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 16272804 Common - GTP-binding protein HI0864 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 16272489 Common rpsR 30S ribosomal protein S18 HI0545 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 16272422 Common hisF imidazole glycerol phosphate synthase subunit HisF HI0474 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 16272223 Common - dihydroneopterin aldolase HI0265 108 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 16272513 Common - DNA-binding transcriptional repressor FabR HI0570 51 COG1309 AcrR, Transcriptional regulator Transcription 16273068 Common ftsA cell division protein HI1142 179 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 16273385 Common muB DNA transposition protein HI1481 17 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 16273323 Common - hypothetical protein HI1416 3 None None None 16273417 Common muN 64 kDa virion protein HI1515 21 COG4228 COG4228, Mu-like prophage DNA circulation protein General function prediction only 16272616 Common gptA xanthine-guanine phosphoribosyltransferase HI0674 72 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 16272812 Pathogen siaA N-acetylneuraminic acid synthase-like protein HI0871 3 None None None 16272584 Common rplL 50S ribosomal protein L7/L12 HI0641 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 16272167 Common rpsP 30S ribosomal protein S16 HI0204 210 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 30995417 Common - peptidyl-prolyl cis-trans isomerase HI1004 166 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 16272697 Common - hypothetical protein HI0756 186 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 16273167 Common - hypothetical protein HI1248 42 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 16272118 Common hflC HflC HI0150 188 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 16272397 Common - hypothetical protein HI0449 4 None None None 16272852 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase HI0915 181 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 16272102 Common - sugar efflux transporter HI0135 140 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16273033 Common nhaC Na+/H+ antiporter HI1107 61 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 16273126 Common cvpA colicin V production protein HI1206 117 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 16273017 Common ccmA heme exporter ATP-binding protein A HI1089 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 16272919 Common smpB SsrA-binding protein HI0981 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 16272278 Common - hypothetical protein HI0325 30 COG2056 COG2056, Predicted permease General function prediction only 30995362 Common - hypothetical protein HI0219 22 COG3059 COG3059, Predicted membrane protein Function unknown 161350015 Common - hypothetical protein HI0467 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 16273639 Common - zinc-binding protein HI0891m 57 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 16272246 Common - periplasmic mercury transport-like protein HI0291 47 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 16272078 Common htpG heat shock protein 90 HI0104 151 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 16272320 Common fdx-1 ferredoxin HI0372 110 COG0633 Fdx, Ferredoxin Energy production and conversion 16273047 Common oppC oligopeptide ABC transporter permease protein HI1122 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 16272140 Common - hypothetical protein HI0175 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 16272207 Common uvrA excinuclease ABC subunit A HI0249 238 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 16272862 Common - hypothetical protein HI0925 47 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 30995461 Common - ABC transporter ATP-binding protein HI1618 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 30995358 Common - esterase/lipase HI0193 168 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 16272160 Common aroC chorismate synthase HI0196 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 30995462 Common - DedA HI1629 130 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 16272410 Common lon ATP-dependent proteinase HI0462 215 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 30995454 Common - hypothetical protein HI1509 4 COG5003 COG5003, Mu-like prophage protein gp37 General function prediction only 16272891 Common dfp bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase HI0953 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 30995476 Common fabI enoyl reductase HI1734 232 COG0623 FabI, Enoyl- acyl-carrier-protein 16272480 Common ureG urease accessory protein HI0536 152 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 16272506 Common asnC DNA-binding transcriptional regulator AsnC HI0563 163 COG1522 Lrp, Transcriptional regulators Transcription 30995433 Common cmk cytidylate kinase HI1219 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 16272454 Common - hypothetical protein HI0510 94 COG1720 COG1720, Uncharacterized conserved protein Function unknown 16272820 Common rplU 50S ribosomal protein L21 HI0880 208 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 30995400 Common - lipooligosaccharide biosynthesis protein HI0765 22 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 16273061 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase HI1135 220 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 16272002 Common lipB lipoyltransferase HI0027 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 16272179 Common - hypothetical protein HI0217 42 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 16273156 Common dnaK heat shock protein 70 HI1237 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 16273182 Common gyrA DNA gyrase subunit A HI1264 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 16272524 Common rpS7 30S ribosomal protein S7 HI0580 247 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 16272408 Common mazG nucleoside triphosphate pyrophosphohydrolase HI0460 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 16272172 Common dam DNA adenine methylase HI0209 100 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 16272830 Common rhlB ATP-dependent RNA helicase RhlB HI0892 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 16273162 Common rsuA 16S pseudouridylate 516 synthase HI1243 194 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 16273544 Common - hypothetical protein HI1657 114 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 16273213 Common - carbonic anhydrase HI1301 146 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 16273625 Common murI glutamate racemase HI1739.2 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 16272460 Common rplA 50S ribosomal protein L1 HI0516 237 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 16273103 Common gmhA phosphoheptose isomerase HI1181 129 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 16273133 Common recJ single-stranded-DNA-specific exonuclease HI1214 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 16273010 Common - hypothetical protein HI1082 52 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 16272989 Common - hypothetical protein HI1058 10 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 16272963 Common - hypothetical protein HI1029 124 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 16272871 Common nrfF cytochrome C-type biogenesis protein HI0934 88 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 16272069 Common - hypothetical protein HI0095 120 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 16272084 Common serS seryl-tRNA synthetase HI0110 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 16272681 Common dnaE DNA polymerase III subunit alpha HI0739 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 16272193 Common - lipoprotein NlpI HI0230 26 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 16273232 Common recD exodeoxyribonuclease V alpha chain HI1322 121 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 16273083 Common trxB thioredoxin reductase HI1158 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 161350024 Common genX lysyl-tRNA synthetase HI0836 225 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 16272401 Common - hypothetical protein HI0453 15 None None None 30995431 Common - hypothetical protein HI1202 61 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 30995471 Common betT high affinity choline transport protein HI1706 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 16272744 Common rpoA DNA-directed RNA polymerase subunit alpha HI0802 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 16272709 Common ftsY cell division protein HI0768 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 16272316 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase HI0368 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 16273400 Common - hypothetical protein HI1498.1 9 COG1693 COG1693, Uncharacterized protein conserved in archaea Function unknown 16273436 Common - hypothetical protein HI1536 33 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 16273295 Common - hypothetical protein HI1386 2 None None None 16272954 Common thiP thiamin transporter membrane protein HI1020 100 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 16272342 Common - translation-associated GTPase HI0393 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 16273476 Common - hypothetical protein HI1582 20 COG3102 COG3102, Uncharacterized protein conserved in bacteria Function unknown 16272034 Common msbA lipid transporter ATP-binding/permease protein HI0060 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 16272829 Common glyA serine hydroxymethyltransferase HI0889 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 16272631 Common glpQ glycerophosphodiester phosphodiesterase HI0689 100 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 16272544 Common tfoX DNA transformation protein HI0601 16 COG3070 TfoX, Regulator of competence-specific genes Transcription 16272095 Common - hypothetical protein HI0125 134 COG2252 COG2252, Permeases General function prediction only 16272614 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase HI0672 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 16273368 Common mrsA MrsA HI1463 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 16272947 Common - putative aldolase HI1012 148 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 16273408 Pathogen - hypothetical protein HI1506 1 None None None 16272009 Common - hypothetical protein HI0034 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 16272815 Common - hypothetical protein HI0874 28 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 16273480 Common - isoleucyl-tRNA synthetas HI1586 46 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 16273261 Common - hypothetical protein HI1351 58 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 16273344 Common xseB exodeoxyribonuclease VII small subunit HI1437 101 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 16272440 Common hslV ATP-dependent protease peptidase subunit HI0496 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 16272721 Common rplB 50S ribosomal protein L2 HI0780 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 16272848 Common kefC glutathione-regulated potassium efflux system protein HI0911 188 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 16273289 Common phoR phosphate regulon sensor protein HI1378 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16272607 Common - hypothetical protein HI0666 11 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 16273355 Common moeA molybdopterin biosynthesis protein HI1448 196 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 16272756 Common uspA universal stress protein A HI0815 37 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 16272568 Common trkA potassium transporter peripheral membrane component HI0625 144 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 16272785 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A HI0844 122 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 16272973 Pathogen ureF urease accessory protein HI1040 1 None None None 16273191 Common metG methionyl-tRNA synthetase HI1276 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16271991 Common lepA GTP-binding protein LepA HI0016 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 16272589 Common asd aspartate-semialdehyde dehydrogenase HI0646 201 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 16273335 Common - short chain dehydrogenase/reductase HI1430 223 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 16272469 Common pgk phosphoglycerate kinase HI0525 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 30995447 Common - hypothetical protein HI1402 5 None None None 16272149 Common - esterase HI0184 99 COG0627 COG0627, Predicted esterase General function prediction only 16273458 Common - hypothetical protein HI1558 55 COG2912 COG2912, Uncharacterized conserved protein Function unknown 30995424 Common ligA NAD-dependent DNA ligase LigA HI1100 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 16272564 Common - D,D-heptose 1,7-bisphosphate phosphatase HI0621.1 133 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 16272752 Common argH argininosuccinate lyase HI0811 235 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 16273193 Common - NAD(P)H-flavin oxidoreductase HI1278 100 COG0778 NfnB, Nitroreductase Energy production and conversion 16273614 Common - hypothetical protein HI1728 44 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 16273371 Common - ABC transporter ATP-binding protein HI1467 235 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 16272595 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase HI0652 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 16271986 Common holD DNA polymerase III subunit psi HI0011 15 COG3050 HolD, DNA polymerase III, psi subunit DNA replication, recombination, and repair 16273207 Common - hypothetical protein HI1293 83 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 30995407 Common - hypothetical protein HI0869 3 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 16273538 Common - hypothetical protein HI1650 7 None None None 16273184 Pathogen - hypothetical protein HI1266 2 None None None 16273073 Common ptsN nitrogen regulatory IIA protein HI1147 129 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 16273442 Common - hypothetical protein HI1542 82 COG0778 NfnB, Nitroreductase Energy production and conversion 16273302 Common hindIIIM modification methylase HI1392 92 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 16273521 Common - hypothetical protein HI1632 27 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 16272968 Common - nucleotide-binding protein HI1034 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 16272414 Common - hypothetical protein HI0466 105 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 16272136 Common nqr6 Na(+)-translocating NADH-quinone reductase subunit F HI0171 157 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 16272534 Common potE putrescine-ornithine antiporter HI0590 155 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 16273510 Common - cobalt transport protein CbiM HI1621 23 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 16273449 Common - ABC transporter ATP-binding protein HI1549 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 16272476 Common dnaG DNA primase HI0532 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 16272702 Common mltC murein transglycosylase C HI0761 137 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 16273435 Common - hypothetical protein HI1535 73 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 16273363 Common - opacity protein HI1457 6 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 16273181 Common metX homoserine O-acetyltransferase HI1263 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 16272932 Common tbp1 transferrin-binding protein 1 precursor HI0994 86 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 16273399 Pathogen - hypothetical protein HI1498 1 None None None 16273351 Common metF 5,10-methylenetetrahydrofolate reductase HI1444 147 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 16272027 Common - zinc-type alcohol dehydrogenase HI0053 204 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 16272901 Common mviN virulence factor HI0964 194 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 16272665 Common - hypothetical protein HI0725 12 None None None 16272350 Common fadL long-chain fatty acid transport protein HI0401 73 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 16272548 Common cysE serine acetyltransferase HI0606 205 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 16272944 Common glpR glycerol-3-phosphate regulon repressor HI1009 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16272703 Common - hypothetical protein HI0762 7 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 16272420 Common hisH imidazole glycerol phosphate synthase subunit HisH HI0472 216 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 16272983 Common - ABC transporter ATP-binding protein HI1051 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 16272975 Common napF ferredoxin-type protein HI1043 80 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 16272225 Common narQ nitrate/nitrite sensor protein NarQ HI0267 132 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 30995391 Common - hemoglobin-binding protein HI0635 45 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 16272955 Common - thiamin ABC transporter ATP-binding protein HI1021 249 COG3840 ThiQ, ABC-type thiamine transport system, ATPase component Coenzyme metabolism 16272786 Common - hypothetical protein HI0845 18 COG3084 COG3084, Uncharacterized protein conserved in bacteria Function unknown 16273517 Common - hypothetical protein HI1628 27 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 16272171 Common aroB 3-dehydroquinate synthase HI0208 207 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 16273197 Common nusA transcription elongation factor NusA HI1283 217 COG0195 NusA, Transcription elongation factor Transcription 16272416 Common hisG ATP phosphoribosyltransferase HI0468 211 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 16273202 Common rbfA ribosome-binding factor A HI1288 173 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 16272732 Common rpsN 30S ribosomal protein S14 HI0791 208 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 16273424 Common - hypothetical protein HI1523 6 None None None 16273387 Common gam host-nuclease inhibitor protein HI1483 9 COG4396 COG4396, Mu-like prophage host-nuclease inhibitor protein Gam General function prediction only 16273455 Common - hypothetical protein HI1555 141 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 16272619 Common - hypothetical protein HI0677 21 None None None 16273266 Common malQ 4-alpha-glucanotransferase HI1356 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 16272042 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase HI0068 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 16273485 Common lolA outer-membrane lipoprotein carrier protein HI1591 67 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 16272162 Common - hypothetical protein HI0198 177 COG0730 COG0730, Predicted permeases General function prediction only 16273613 Common argG argininosuccinate synthase HI1727 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 16273252 Common - hypothetical protein HI1343 231 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 16272541 Common ccrB camphor resistance protein CrcB HI0597.1 40 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 16273307 Common fumC fumarate hydratase HI1398 218 COG0114 FumC, Fumarase Energy production and conversion 16273608 Common map methionine aminopeptidase HI1722 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 16273190 Common tehB tellurite resistance protein TehB HI1275 41 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 16273108 Common dppC dipeptide ABC transporter permease protein HI1186 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 16273674 Common - two component signal transduction system protein HI0219a 203 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 30995429 Common - opacity protein HI1174 5 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 16272514 Common oxyR DNA-binding transcriptional regulator OxyR HI0571 190 COG0583 LysR, Transcriptional regulator Transcription 16272825 Common dipZ thiol:disulfide interchange protein precursor HI0885 152 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 16273601 Common - ribosome-associated GTPase HI1714 163 COG1162 COG1162, Predicted GTPases General function prediction only 30995458 Common radA DNA repair protein RadA HI1597 217 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 16272144 Common pflA pyruvate formate lyase-activating enzyme 1 HI0179 80 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 161350026 Common recX recombination regulator RecX HI0599 81 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 16273415 Pathogen - hypothetical protein HI1513 4 COG4518 COG4518, Mu-like prophage FluMu protein gp41 Function unknown 30995439 Common - nuclease HI1296 76 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 16273005 Common cydA cytochrome D ubiquinol oxidase subunit I HI1076 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 16272306 Common - thiamine biosynthesis protein HI0357 91 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 16273271 Common - hypothetical protein HI1361 142 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 16273114 Pathogen - hypothetical protein HI1192 1 None None None 16273278 Common - zinc protease HI1368 197 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 16272008 Common - hypothetical protein HI0033 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 16272283 Common oapB opacity associated protein HI0331 3 None None None 16273216 Common nusB transcription antitermination protein NusB HI1304 189 COG0781 NusB, Transcription termination factor Transcription 30995441 Common ribH riboflavin synthase subunit beta HI1303 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 16272727 Common rpsQ 30S ribosomal protein S17 HI0786 237 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 16273620 Common - hypothetical protein HI1736 8 None None None 16273405 Common - G protein HI1503 4 COG5005 COG5005, Mu-like prophage protein gpG General function prediction only 16272990 Common rnhB ribonuclease HII HI1059 239 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 16272032 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase HI0058 147 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 16271985 Common rimI ribosomal-protein-alanine N-acetyltransferase HI0010 103 COG0456 RimI, Acetyltransferases General function prediction only 16272272 Common - hypothetical protein HI0318 20 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 16273321 Pathogen - hypothetical protein HI1414 1 None None None 16272929 Common recF recombination protein F HI0991 165 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 30995365 Common udp uridine phosphorylase HI0280 100 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 16273218 Common pgpA phosphatidylglycerophosphatase A HI1306 95 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 16272779 Common - small protein A HI0838 60 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 16273150 Common lpdA dihydrolipoamide dehydrogenase HI1231 240 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 16272743 Common rpsD 30S ribosomal protein S4 HI0801 223 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 16273410 Common - hypothetical protein HI1508 22 COG4387 COG4387, Mu-like prophage protein gp36 Function unknown 16273293 Common rsgA ferritin HI1384 84 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 16273131 Common lysS lysyl-tRNA synthetase HI1211 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 16272879 Common recC exodeoxyribonuclease V gamma chain HI0942 69 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 16273540 Common spr lipoprotein HI1652 140 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 16272258 Common - hypothetical protein HI0303 206 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 16273080 Common nrdG anaerobic ribonucleotide reductase-activating protein HI1155 59 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 16272250 Common rho transcription termination factor Rho HI0295 206 COG1158 Rho, Transcription termination factor Transcription 16272720 Common rplW 50S ribosomal protein L23 HI0779 113 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 16272683 Common - hypothetical protein HI0742 5 None None None 16272039 Common yjeE ATPase HI0065 207 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 16272604 Common oapA hemoglobin-binding protein HI0661 66 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 16272482 Common ureE urease accessory protein UreE HI0538 15 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 16273027 Common - cell division protein ZipA HI1101 41 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 16272495 Common apaH diadenosine tetraphosphatase HI0551 91 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 16272437 Common - hypothetical protein HI0489 74 COG1238 COG1238, Predicted membrane protein Function unknown 16272505 Common - hypothetical protein HI0562 104 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 16273547 Common nrdB ribonucleotide-diphosphate reductase subunit beta HI1660 152 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 16272962 Common - hypothetical protein HI1028 104 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 16272877 Common - hypothetical protein HI0940 4 None None None 16272003 Common - hypothetical protein HI0028 24 COG2921 COG2921, Uncharacterized conserved protein Function unknown 16272694 Common anmK anhydro-N-acetylmuramic acid kinase HI0753 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 161350016 Common clpP ATP-dependent Clp protease proteolytic subunit HI0714 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 16273473 Common - glycosyl transferase HI1578 201 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 16272872 Common dsbE thiol-disulfide interchange protein HI0935 117 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 16273564 Common - cell morphogenesis/cell wall metabolism regulator HI1677 45 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 16272840 Common - hypothetical protein HI0902 83 COG0730 COG0730, Predicted permeases General function prediction only 16273332 Common - hypothetical protein HI1427 10 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 16272770 Common - soluble lytic murein transglycosylase HI0829 159 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 16272063 Common thrA bifunctional aspartokinase I/homeserine dehydrogenase I HI0089 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 16273096 Common metX S-adenosylmethionine synthetase HI1172 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 16272461 Common rplK 50S ribosomal protein L11 HI0517 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 16272159 Common - potassium efflux protein KefA HI0195.1 211 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 16272529 Common - hypothetical protein HI0585 24 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 16273183 Common - hypothetical protein HI1265 40 COG1944 COG1944, Uncharacterized conserved protein Function unknown 16273541 Common - hypothetical protein HI1654 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 16273020 Common ccmD heme exporter protein D HI1092 12 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 16272908 Common accB acetyl-CoA carboxylase biotin carboxyl carrier protein subunit HI0971 191 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 16272191 Pathogen - hypothetical protein HI0228 1 None None None 16272198 Common - arsenate reductase HI0236 113 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 16272586 Common bisC biotin sulfoxide reductase HI0643 179 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 16273528 Common sapB peptide ABC transporter permease protein HI1639 207 COG4168 SapB, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 16272169 Common - 5'-nucleotidase HI0206 128 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 16272152 Common - hypothetical protein HI0188 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 16273327 Common - hypothetical protein HI1422 20 COG3561 COG3561, Phage anti-repressor protein Transcription 16272864 Common glyQ glycyl-tRNA synthetase subunit alpha HI0927 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 30995416 Common leuA 2-isopropylmalate synthase HI0986 215 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 16272314 Common - fimbrial biogenesis and twitching motility protein HI0366 27 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 16272249 Common metJ transcriptional repressor protein MetJ HI0294 23 COG3060 MetJ, Transcriptional regulator of met regulon Transcription / Amino acid transport and metabolism 16273599 Common ptsI phosphoenolpyruvate-protein phosphotransferase HI1712 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 16272869 Common eno phosphopyruvate hydratase HI0932 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 16273046 Common oppD oligopeptide transporter ATP-binding component HI1121 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 16273121 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase HI1201 222 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 16273453 Common bioF 8-amino-7-oxononanoate synthase HI1553 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 16272927 Common leuD isopropylmalate isomerase small subunit HI0989 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 30995363 Common - hypothetical protein HI0220.2 56 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 16273220 Common dapB dihydrodipicolinate reductase HI1308 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 16273185 Common - hypothetical protein HI1268 27 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 16272387 Common comA competence protein A HI0439 4 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 16272817 Common obgE GTPase ObgE HI0877 249 COG0536 Obg, Predicted GTPase General function prediction only 16272077 Common - hypothetical protein HI0103 109 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 16272276 Common gloA lactoylglutathione lyase HI0323 128 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 16273301 Common valS valyl-tRNA synthetase HI1391 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 30995405 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase HI0831 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 16273116 Common sucC succinyl-CoA synthetase beta subunit HI1196 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 16272216 Common - glycosyl transferase HI0258 35 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 16273649 Common pstS periplasmic ABC-type phosphate transport component HI1383m 99 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 16273165 Common - hypothetical protein HI1246 71 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 16272025 Common - hypothetical protein HI0051 67 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 16272430 Common atpF F0F1 ATP synthase subunit B HI0483 85 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 16272651 Common - hypothetical protein HI0711 32 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 16273008 Common - amino acid ABC transporter periplasmic-binding protein HI1080 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 16272394 Common fruA PTS system fructose-specific IIBC component HI0446 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 16273231 Common recB exodeoxyribonuclease V beta chain HI1321 216 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 16272097 Common afuB ferric transport system permease-like protein HI0129 221 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 16273236 Common - hypothetical protein HI1326 11 None None None 16272857 Common - hypothetical protein HI0920 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 16272142 Common - lipoprotein HI0177 122 COG4105 ComL, DNA uptake lipoprotein General function prediction only 16272897 Common exoII beta-hexosaminidase HI0959 178 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 16272427 Common atpG F0F1 ATP synthase subunit gamma HI0480 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 16272060 Common metB cystathionine gamma-synthase HI0086 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 16272116 Pathogen - hypothetical protein HI0148.1 1 None None None 30995384 Common ureF permease/urease accessory protein HI0537 85 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 16272091 Common - UDP-N-acetylmuramoylalanine-D-glutamate ligase-like protein HI0121 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 16272121 Common acpP acyl carrier protein HI0154 182 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16273071 Common pheA chorismate mutase/prephenate dehydratase HI1145 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 16272796 Common polA DNA polymerase I HI0856 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 16272265 Common - hypothetical protein HI0310 4 None None None 16272790 Common - sigma-E factor regulatory protein HI0850 20 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 16272581 Common - hypothetical protein HI0638 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 16272122 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase HI0155 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 16272447 Common rbsC ribose ABC transporter permease protein HI0503 160 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 16273594 Common ygiY sensor protein HI1707 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 16273503 Common ribE riboflavin synthase subunit alpha HI1613 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 16272892 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase HI0954 182 COG0756 Dut, dUTPase Nucleotide transport and metabolism 16273272 Common pntA NAD(P) transhydrogenase subunit alpha HI1362 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 16272295 Common napD NapD HI0343 16 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 30995371 Common - hypothetical protein HI0391 7 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 16272637 Common - exopolyphosphatase HI0695 180 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 16272512 Common greB transcription elongation factor GreB HI0569 187 COG0782 GreA, Transcription elongation factor Transcription 16273136 Common - transferrin-binding protein HI1217 29 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 16272570 Common - hypothetical protein HI0627 32 COG2938 COG2938, Uncharacterized conserved protein Function unknown 16272059 Common ldhA D-lactate dehydrogenase HI0085 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 16272457 Common hindIIM modification methylase HI0513 32 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 16272552 Common fucP L-fucose permease HI0610 46 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 16272242 Common mtr tryptophan-specific transport protein HI0287 31 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 16273200 Common hsdS type I restriction/modification specificity protein HI1286 83 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 16272710 Common ftsE cell division ATP-binding protein HI0769 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 16272831 Common - transcriptional repressor HI0893 37 COG1309 AcrR, Transcriptional regulator Transcription 16273507 Common aspC aromatic amino acid aminotransferase HI1617 73 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 16273378 Common - ABC transporter ATP-binding protein HI1474 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 16272019 Common - hypothetical protein HI0044 82 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 16273312 Common yhxB tail fibre protein/phosphomannomutase HI1403 5 None None None 16272653 Common tig trigger factor HI0713 216 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 16273143 Common pyrF orotidine 5'-phosphate decarboxylase HI1224 172 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 16272673 Pathogen - hypothetical protein HI0732 1 None None None 16272838 Common proB gamma-glutamyl kinase HI0900 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 16273174 Common - hypothetical protein HI1255 23 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 30995351 Common uxuR uxu operon regulator HI0054 123 COG2186 FadR, Transcriptional regulators Transcription 16272645 Common - hypothetical protein HI0704 3 None None None 16272747 Common - hypothetical protein HI0806 49 COG0730 COG0730, Predicted permeases General function prediction only 16273347 Common sspB ClpXP protease specificity-enhancing factor HI1440 64 COG2969 SspB, Stringent starvation protein B General function prediction only 16273382 Common muA transposase HI1478 17 None None None 30995468 Common - hypothetical protein HI1664 126 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 16273249 Common - hypothetical protein HI1339 6 None None None 16272331 Common tolA cell envelope integrity inner membrane protein TolA HI0383 19 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 16273229 Common - hypothetical protein HI1317 51 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 16273339 Common ybaK transcriptional regulator-like protein HI1434 123 COG2606 EbsC, Uncharacterized conserved protein Function unknown 16272562 Common hlpA 28 kDa outer membrane protein HI0620 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 16272485 Common ureA urease subunit gamma HI0541 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 16272369 Common - hypothetical protein HI0420 20 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 16273579 Common modB molybdate ABC transporter permease protein HI1692 229 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 16272516 Common slyX hypothetical protein HI0573 43 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 16273493 Common - hypothetical protein HI1603 39 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 16271978 Common - long chain fatty acid CoA ligase HI0002 214 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 16272593 Common - hypothetical protein HI0650 4 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 16272471 Common fdx-2 ferredoxin HI0527 104 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 16272729 Common rplN 50S ribosomal protein L14 HI0788 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 16272131 Common - Na(+)-translocating NADH-quinone reductase subunit A HI0164 43 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 16273016 Common sodA superoxide dismutase HI1088 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 16273483 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase HI1589 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 16272942 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase HI1007 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 16272406 Common - stationary-phase survival protein SurA HI0458 141 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 16273380 Common - transcriptional regulatory protein HI1476 39 COG2932 COG2932, Predicted transcriptional regulator Transcription 16272006 Common rodA rod shape-determining protein HI0031 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 16272800 Common - 23S rRNA (guanosine-2'-O-)-methyltransferase HI0860 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 16273397 Pathogen - hypothetical protein HI1496 1 None None None 16273511 Common - hypothetical protein HI1622 5 None None None 16273403 Common - hypothetical protein HI1501 28 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 16273106 Common dppF dipeptide transporter ATP-binding subunit HI1184 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 16273268 Common glgX glycogen operon protein HI1358 162 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 16272610 Common - hypothetical protein HI0668 20 COG3074 COG3074, Uncharacterized protein conserved in bacteria Function unknown 16273300 Common trpC bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase HI1389.1 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 16273117 Common sucD succinyl-CoA synthetase alpha subunit HI1197 217 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 16272173 Common pgpB phosphatidylglycerophosphatase B HI0211 29 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 30995376 Common ybaB hypothetical protein HI0442 169 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 16272015 Common - hypothetical protein HI0040 7 None None None 16272734 Common rplF 50S ribosomal protein L6 HI0793 234 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 16273437 Common licA lic-1 operon protein HI1537 24 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 16273353 Common - hypothetical protein HI1446 23 COG3100 COG3100, Uncharacterized protein conserved in bacteria Function unknown 16273597 Common - hypothetical protein HI1710 4 None None None 16273426 Common rfaE bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase HI1526 176 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 16272964 Common - hypothetical protein HI1030 79 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 16273360 Common - cytochrome C-type biogenesis protein HI1454 84 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 16272352 Common mutH DNA mismatch repair protein HI0403 28 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 16272324 Common - hypothetical protein HI0376 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 16272546 Common cyaA adenylate cyclase HI0604 25 COG3072 CyaA, Adenylate cyclase Nucleotide transport and metabolism 16272934 Common rpmH 50S ribosomal protein L34 HI0998 191 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 30995388 Common hemX heme biosythesis-like protein HI0603m 56 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 16272418 Common hisC histidinol-phosphate aminotransferase HI0470 234 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 16272758 Common - hypothetical protein HI0817 29 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 16273376 Common - iron chelatin ABC transporter periplasmic-binding protein HI1472 97 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 16271996 Common citG CitG protein HI0021 46 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 30995472 Common - hypothetical protein HI1720 23 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 16272001 Common lipA lipoyl synthase HI0026 191 COG0320 LipA, Lipoate synthase Coenzyme metabolism 16272189 Common brnQ branched-chain amino acid transport system II carrier protein HI0226 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 16273572 Common - electron transport complex protein RnfC HI1685 80 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 16272048 Common - nucleotidyltransferase HI0074 27 None None None 16272977 Common dmsC anaerobic dimethyl sulfoxide reductase chain C HI1045 26 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 16273204 Common tyrA bifunctional chorismate mutase/prephenate dehydrogenase HI1290 99 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 16272451 Common - hypothetical protein HI0507 55 COG2862 COG2862, Predicted membrane protein Function unknown 16273029 Common cysK cysteine synthetase HI1103 218 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 16273581 Common modE molybdenum transport protein HI1694 85 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 16272588 Common pldB lysophospholipase L2 HI0645 72 COG2267 PldB, Lysophospholipase Lipid metabolism 16273526 Common - hypothetical protein HI1637 42 COG3106 COG3106, Predicted ATPase General function prediction only 16272875 Common - hypothetical protein HI0938 4 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 16273263 Common cafA ribonuclease G HI1353 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 16272464 Common - hypothetical protein HI0520 82 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 16272640 Common slyD peptidyl-prolyl cis-trans isomerase FKBP-type HI0699 128 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 16272470 Common - hypothetical protein HI0526 35 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 16272985 Common - hypothetical protein HI1053 18 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 16272623 Common ilvY DNA-binding transcriptional regulator IlvY HI0681 190 COG0583 LysR, Transcriptional regulator Transcription 16272154 Common fur ferric uptake regulation protein HI0190 198 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 30995451 Common - RNA polymerase sigma factor HI1459 106 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 16272559 Common - hypothetical protein HI0617 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 30995367 Common ntpA dATP pyrophosphohydrolase HI0316 40 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 16273451 Common - biotin synthesis protein HI1551 24 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 16272065 Common - hypothetical protein HI0091 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 16273157 Common dnaJ heat shock protein HI1238 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 16272660 Common htpX heat shock protein HtpX HI0720 190 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 16273430 Common gltS glutamate permease HI1530 56 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 16272041 Common mutL DNA mismatch repair protein HI0067 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 16272836 Common emrA multidrug resistance protein A HI0898 146 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 16273171 Common - putative ABC transporter ATP-binding protein HI1252 244 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 16273545 Common - hypothetical protein HI1658 63 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 16272425 Common atpC F0F1 ATP synthase subunit epsilon HI0478 193 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 16272503 Pathogen - hypothetical protein HI0559.1 1 None None None 16273318 Common - terminase small subunit HI1411 6 COG3728 XtmA, Phage terminase, small subunit DNA replication, recombination, and repair 16273529 Common sapC peptide ABC transporter permease protein HI1640 209 COG4171 SapC, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 16273022 Common ccmF cytochrome C-type biogenesis protein HI1094 146 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 16273338 Common usg1 aspartate-semialdehyde dehydrogenase HI1433 127 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 16272550 Common - hypothetical protein HI0608 149 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 16272667 Common lysA diaminopimelate decarboxylase HI0727 219 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 16272685 Common - hypothetical protein HI0744 82 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 16273003 Common - hypothetical protein HI1074 28 COG2707 COG2707, Predicted membrane protein Function unknown 16272285 Common rumA 23S rRNA 5-methyluridine methyltransferase HI0333 201 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 30995443 Common - sulfatase-like protein HI1316 23 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 16272303 Pathogen - hypothetical protein HI0352 4 None None None 16273629 Common gmk guanylate kinase HI1743 212 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 16273163 Common - hypothetical protein HI1244 7 COG3955 COG3955, Exopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 16272329 Common pal peptidoglycan-associated outer membrane lipoprotein HI0381 149 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 16272705 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase HI0764 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 16272749 Common frr ribosome recycling factor HI0808 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 16272634 Common gptB xanthine-guanine phosphoribosyltransferase HI0692 72 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 16272602 Common - hypothetical protein HI0659 5 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 16272345 Common - hypothetical protein HI0396 57 COG2850 COG2850, Uncharacterized conserved protein Function unknown 16273444 Common - NAD(P)H oxidoreductase HI1544 88 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 16272647 Common mutS DNA mismatch repair protein HI0707 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 30995437 Common hsdM type I modification enzyme HI1287 160 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 16272252 Common - protein transport protein HI0297 141 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 16273495 Common - hypothetical protein HI1605 31 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 16272520 Common - hypothetical protein HI0576.1 36 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 16272725 Common rplP 50S ribosomal protein L16 HI0784 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 16273090 Common hisH histidinol-phosphate aminotransferase HI1166 238 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 16273152 Common aceE pyruvate dehydrogenase subunit E1 HI1233 156 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 16272953 Common tbpA thiamin ABC transporter periplasmic-binding protein HI1019 51 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 16272030 Common - hypothetical protein HI0056 103 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 16273087 Common - hypothetical protein HI1163 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 16272782 Common - hypothetical protein HI0841 34 COG3083 COG3083, Predicted hydrolase of alkaline phosphatase superfamily General function prediction only 16273188 Common - hypothetical protein HI1273 35 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 16272214 Common - lipoprotein HI0256 16 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 16272363 Pathogen - hypothetical protein HI0414 2 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 16272234 Common rbn ribonuclease BN HI0276 143 COG1295 Rbn, Predicted membrane protein Function unknown 16272493 Common ksgA dimethyladenosine transferase HI0549 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 16272399 Common - hypothetical protein HI0451 2 None None None 16272010 Common - hypothetical protein HI0035 56 COG2985 COG2985, Predicted permease General function prediction only 16273234 Common - lon protease HI1324 97 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 16272099 Common udk uridine kinase HI0132 85 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 161350018 Common lrp leucine-responsive transcriptional regulator HI1596 149 COG1522 Lrp, Transcriptional regulators Transcription 16273285 Common mukB cell division protein MukB HI1374 84 COG3096 MukB, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 30995396 Common - hypothetical protein HI0722 130 COG1739 COG1739, Uncharacterized conserved protein Function unknown 30995428 Common - hypothetical protein HI1165 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 16272855 Common - hypothetical protein HI0918 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 16272789 Common trmA tRNA (uracil-5-)-methyltransferase HI0848 161 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 16272625 Common glpC sn-glycerol-3-phosphate dehydrogenase subunit C HI0683 180 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 16272844 Common - hypothetical protein HI0907 4 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 16272895 Common crp cAMP-regulatory protein HI0957 159 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 16272115 Common - hypothetical protein HI0148 22 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 16272792 Common - hypothetical protein HI0852 184 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16272367 Common - transport protein HI0418 127 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16273647 Common - SAM-dependent methyltransferase HI1195m 45 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 16272335 Common dinG ATP-dependent helicase HI0387 153 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 16273044 Common lapB membrane protein HI1119 19 COG2990 VirK, Uncharacterized protein conserved in bacteria Function unknown 16272579 Common - hypothetical protein HI0636 15 COG3691 COG3691, Uncharacterized protein conserved in bacteria Function unknown 16272205 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase HI0245 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 16272338 Common fadD long-chain-fatty-acid--CoA ligase HI0390.1 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16272806 Common - hypothetical protein HI0866 14 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 16272056 Common - hypothetical protein HI0082 4 None None None 16272865 Common hktE catalase HI0928 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 16273637 Common - SAM-dependent methyltransferase HI0849m 49 None None None 16273611 Common ponB penicillin-binding protein 1B HI1725 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 30995414 Common menC O-succinylbenzoate synthase HI0969 48 COG1441 MenC, O-succinylbenzoate synthase Coenzyme metabolism 16273557 Common - putative solute/DNA competence effector HI1670 26 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 16273325 Common - hypothetical protein HI1419 42 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 30995465 Common tldD predicted Zn-dependent protease HI1653 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 16273176 Common mfd transcription-repair coupling factor HI1258 228 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 16272023 Common - D-mannonate oxidoreductase HI0048 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 16272244 Common sdaC serine transporter HI0289 41 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 30995404 Common mglB galactose ABC transporter periplasmic-binding protein HI0822 96 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 16272764 Common mglA galactose/methyl galaxtoside transporter ATP-binding protein HI0823 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 16272889 Common rpmB 50S ribosomal protein L28 HI0951 154 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 16273299 Common trpD anthranilate phosphoribosyltransferase HI1389 218 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 16273345 Common ispA geranyltranstransferase HI1438 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 16273247 Common mrsA MrsA HI1337 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 16272379 Common - hypothetical protein HI0431 26 COG3068 COG3068, Uncharacterized protein conserved in bacteria Function unknown 16273319 Common - hypothetical protein HI1412 27 COG3646 COG3646, Uncharacterized phage-encoded protein Function unknown 16272017 Common - pseudouridine synthase-like protein HI0042 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 16272849 Common - hypothetical protein HI0912 35 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 16272274 Common vapB virulence-associated protein B HI0321 10 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 16273145 Common - DNA replication initiation factor HI1225.1 191 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 16272904 Pathogen - hypothetical protein HI0967 1 None None None 16272380 Common nudC NADH pyrophosphatase HI0432 112 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 16272860 Common holA DNA polymerase III subunit delta HI0923 64 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 16272655 Common clpX ATP-dependent protease ATP-binding subunit HI0715 239 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 16272958 Common ulaD 3-keto-L-gulonate-6-phosphate decarboxylase HI1024 56 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 16272675 Common plsC 1-acyl-glycerol-3-phosphate acyltransferase HI0734 132 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 16272194 Common deaD ATP-dependent RNA helicase HI0231 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 16273679 Common rpmI 50S ribosomal protein L35 HI1319m 30 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 30995353 Common - hypothetical protein HI0094 37 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 16272992 Common lpxA UDP-N-acetylglucosamine acyltransferase HI1061 158 COG1043 LpxA, Acyl- acyl carrier protein 16272915 Common fic cell filamentation protein HI0977 32 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 30995466 Common nrdA ribonucleotide-diphosphate reductase subunit alpha HI1659 201 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 16273432 Common grxA glutaredoxin 1 HI1532 54 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 16273428 Common parE DNA topoisomerase IV subunit B HI1528 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 16272719 Common rplD 50S ribosomal protein L4 HI0778 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 16273491 Common - hypothetical protein HI1601 11 COG3767 COG3767, Uncharacterized low-complexity protein Function unknown 16273066 Common ddl D-alanine--D-alanine ligase HI1140 215 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 16272712 Common atoB acetyl-CoA acetyltransferase HI0771 179 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 16273137 Common lctP L-lactate permease HI1218 103 COG1620 LldP, L-lactate permease Energy production and conversion 16272501 Common zwf glucose-6-phosphate 1-dehydrogenase HI0558 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 16272110 Common - hypothetical protein HI0143 96 COG1737 RpiR, Transcriptional regulators Transcription 16272450 Common rbsR RBS repressor HI0506 130 COG1609 PurR, Transcriptional regulators Transcription 16273141 Common - hypothetical protein HI1222 8 COG3771 COG3771, Predicted membrane protein Function unknown 16273384 Pathogen - hypothetical protein HI1480 1 None None None 16272670 Common proS prolyl-tRNA synthetase HI0729 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16273592 Common pepA leucyl aminopeptidase HI1705 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 16273468 Common pykA pyruvate kinase HI1573 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 16271983 Common fdxI formate dehydrogenase gamma subunit HI0008 70 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 16273622 Common - hypothetical protein HI1738 82 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 16272445 Common rbsD high affinity ribose transport protein HI0501 45 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 16273013 Common - hypothetical protein HI1085 99 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 16272124 Common fabH 3-oxoacyl-(acyl carrier protein) synthase III HI0157 227 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 30995386 Common dod ribulose-phosphate 3-epimerase HI0566 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 16272677 Common - sodium-dependent transporter HI0736 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 16273414 Common - hypothetical protein HI1512 5 None None None 16273419 Common - hypothetical protein HI1519 17 COG4381 COG4381, Mu-like prophage protein gp46 Function unknown 16272133 Common - Na(+)-translocating NADH-quinone reductase subunit C HI0167 48 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 16273501 Common sfsA sugar fermentation stimulation protein A HI1611 107 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 16272799 Common clpB ATP-dependent Clp protease ATPase subunit HI0859 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 16272128 Common gor glutathione reductase HI0161 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 16272297 Common napH quinol dehydrogenase membrane component HI0346 55 COG0348 NapH, Polyferredoxin Energy production and conversion 16272882 Common degS protease HI0945 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 16273550 Common - hypothetical protein HI1663 217 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 16272175 Common - oligopeptide transporter periplasmic-binding protein HI0213 161 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 16273439 Common licC lic-1 operon protein HI1539 51 COG4750 LicC, CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes Cell envelope biogenesis, outer membrane 16273274 Common - transcriptional regulator HI1364 161 COG0583 LysR, Transcriptional regulator Transcription 161350021 Common hrpa ATP-dependent RNA helicase HrpA HI1070 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 16273078 Common hpt hypoxanthine-guanine phosphoribosyltransferase HI1153 149 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 16273586 Common - lipopolysaccharide biosynthesis protein HI1699 6 None None None 16273505 Common purE phosphoribosylaminoimidazole carboxylase catalytic subunit HI1615 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 149212744 Common - hypothetical protein HI1435 190 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 16272608 Pathogen - hypothetical protein HI0666.1 1 None None None 30995430 Common dppB dipeptide ABC transporter permease protein HI1187 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 16272826 Common - hypothetical protein HI0886 35 COG2259 COG2259, Predicted membrane protein Function unknown 16273076 Common - hypothetical protein HI1151 62 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 16272687 Common dcuB anaerobic C4-dicarboxylate transporter HI0746 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 16272925 Common leuB 3-isopropylmalate dehydrogenase HI0987 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 16273585 Common - lipopolysaccharide biosynthesis protein HI1698 220 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 16272994 Common - hypothetical protein HI1063 3 None None None 16272465 Common - hypothetical protein HI0521 14 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 16273409 Pathogen - hypothetical protein HI1507 1 None None None 16273084 Common hemH ferrochelatase HI1160 154 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 16272641 Common - hypothetical protein HI0700 23 COG3076 COG3076, Uncharacterized protein conserved in bacteria Function unknown 16272596 Common - lipopolysaccharide biosynthesis protein HI0653 127 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 16272254 Common - prepilin peptidase-dependent protein D HI0299 20 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 16272774 Common frdC fumarate reductase subunit C HI0833 23 COG3029 FrdC, Fumarate reductase subunit C Energy production and conversion 16273624 Common lldD L-lactate dehydrogenase HI1739.1 120 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 16272226 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase HI0268 201 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 16272328 Common - hypothetical protein HI0380 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 16273574 Common rnfG electron transport complex protein RnfG HI1687 58 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 16272383 Common comE competence protein E HI0435 141 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 16272287 Common dgkA diacylglycerol kinase HI0335 110 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 16272343 Common pth peptidyl-tRNA hydrolase HI0394 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 16272301 Common - permease HI0350 110 None None None 16272941 Common lspA lipoprotein signal peptidase HI1006 196 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 16272066 Common - hypothetical protein HI0092 45 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 16272037 Common pcnB polyA polymerase HI0063 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 16273401 Common - hypothetical protein HI1499 11 None None None 16273251 Common - hemoglobin-binding protein HI1341 13 COG5595 COG5595, Zn-ribbon-containing, possibly nucleic-acid-binding protein General function prediction only 16273356 Common moeB molybdopterin biosynthesis protein MoeB HI1449 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 16272912 Common panF sodium/panthothenate symporter HI0975 159 COG4145 PanF, Na+/panthothenate symporter Coenzyme metabolism 16273265 Common - hypothetical protein HI1355 75 COG2983 COG2983, Uncharacterized conserved protein Function unknown 16273233 Common - hypothetical protein HI1323 17 COG3120 COG3120, Uncharacterized protein conserved in bacteria Function unknown 16273055 Common - hypothetical protein HI1129 143 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 16273477 Common argS arginyl-tRNA synthetase HI1583 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16273446 Common - ImpA HI1546 6 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 16273023 Common dsbE thiol-disulfide interchange protein HI1095 134 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 16272766 Common - hypothetical protein HI0825 4 None None None 16273101 Common artI arginine ABC transporter periplasmic-binding protein HI1179 148 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 16273513 Common merR2 mercuric resistance operon regulatory protein HI1623 150 COG0789 SoxR, Predicted transcriptional regulators Transcription 16272178 Common hsdS type I restriction/modification specificity protein HI0216 47 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 16272821 Common ispB octaprenyl-diphosphate synthase HI0881 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 16273187 Common - ABC transporter ATP-binding protein HI1272 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 16272523 Common fusA elongation factor G HI0579 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 16273164 Common - malic enzyme HI1245 217 COG0281 SfcA, Malic enzyme Energy production and conversion 16273525 Common ppc phosphoenolpyruvate carboxylase HI1636 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 16272580 Common trpS tryptophanyl-tRNA synthetase HI0637 232 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16273110 Common uvrD DNA-dependent helicase II HI1188 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 16273390 Pathogen - hypothetical protein HI1487 1 None None None 16272022 Common eda keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase HI0047 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 16273684 Common selD selenophosphate synthase HI0200m 135 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 16272557 Common fucR L-fucose operon activator HI0615 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 16273212 Common - ABC transporter ATPase component HI1300 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 16272318 Common - hypothetical protein HI0370 65 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 30995436 Common - hypothetical protein HI1282 175 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 16272083 Pathogen - hypothetical protein HI0109 2 COG3765 WzzB, Chain length determinant protein Cell envelope biogenesis, outer membrane 16273431 Common rimK ribosomal protein S6 modification protein HI1531 128 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 16273320 Common - hypothetical protein HI1413 2 None None None 16272137 Common - lipoprotein HI0172 137 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 16272736 Common rpsE 30S ribosomal protein S5 HI0795 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 16273603 Common - undecaprenyl-phosphate alpha-N-acetylglucosaminyltransferase HI1716 149 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 16273092 Common - hypothetical protein HI1168 22 COG2926 COG2926, Uncharacterized protein conserved in bacteria Function unknown 16273448 Common - outer membrane-specific lipoprotein transporter subunit LolE HI1548 154 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 16272245 Common - hypothetical protein HI0290 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 16273374 Common - iron chelatin ABC transporter ATP-binding protein HI1470 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 16272545 Common hemY HemY HI0602 37 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 16272533 Common - sigma factor regulatory protein HI0589 26 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 16272967 Common serB phosphoserine phosphatase HI1033 149 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 16272322 Common - hypothetical protein HI0374 8 None None None 16273206 Common - hypothetical protein HI1292 13 COG5595 COG5595, Zn-ribbon-containing, possibly nucleic-acid-binding protein General function prediction only 16272049 Common nrdD anaerobic ribonucleoside triphosphate reductase HI0075 100 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 16272739 Common secY preprotein translocase subunit SecY HI0798 238 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 16272155 Common fldA flavodoxin FldA HI0191 74 COG0716 FldA, Flavodoxins Energy production and conversion 16272950 Common gntP gluconate permease HI1015 76 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 16272353 Common mesJ cell cycle protein HI0404 213 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 16273596 Common - hypothetical protein HI1709 25 COG3111 COG3111, Uncharacterized conserved protein Function unknown 16273370 Common - cell division FtsH-related protein HI1465 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 16272959 Common sgbE L-ribulose-5-phosphate 4-epimerase HI1025 106 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 16272979 Common dmsA anaerobic dimethyl sulfoxide reductase chain A HI1047 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 16273014 Common - hypothetical protein HI1086 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 16272755 Common alaS alanyl-tRNA synthetase HI0814 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16272751 Common hslO Hsp33-like chaperonin HI0810 136 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 30995348 Common citE citrate lyase beta chain HI0023 112 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 30995474 Common - hypothetical protein HI1724 22 COG3112 COG3112, Uncharacterized protein conserved in bacteria Function unknown 16273282 Common - hypothetical protein HI1371.1 161 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 16271994 Common - hypothetical protein HI0019 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 16273159 Common - hypothetical protein HI1240 133 COG2860 COG2860, Predicted membrane protein Function unknown 16272615 Common ftsB cell divison protein FtsB HI0673 61 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 16273119 Common - hypothetical protein HI1199 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 16273310 Common pyrD dihydroorotate dehydrogenase 2 HI1401 176 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 16272948 Common - hypothetical protein HI1013 78 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 16273367 Common - hypothetical protein HI1462.2 46 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 16272841 Common lgt prolipoprotein diacylglyceryl transferase HI0904 208 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 16272148 Common - amino acid carrier protein HI0183 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 16272560 Common - glp protein HI0618 110 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 16272567 Common sun sun protein HI0624 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 16273481 Common hns DNA-binding protein H-NS HI1587 27 COG2916 Hns, DNA-binding protein H-NS General function prediction only 30995395 Common - cell developmental protein SirA HI0721 80 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 16273379 Common - hypothetical protein HI1475 120 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 16273303 Pathogen hindIIIR type II restriction endonuclease HI1393 2 None None None 16272633 Common glpK glycerol kinase HI0691 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 16272443 Common - oxidoreductase HI0499 132 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 16272185 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein HI0222 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 161350023 Common pdxH pyridoxamine 5'-phosphate oxidase HI0863 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 16273277 Common thrS threonyl-tRNA synthetase HI1367 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 16272679 Common ilvD dihydroxy-acid dehydratase HI0738 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 16273533 Common truA tRNA pseudouridine synthase A HI1644 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 16272269 Common - hypothetical protein HI0315 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 16272376 Common dsbB disulfide bond formation protein B HI0428 54 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 16272054 Common - hypothetical protein HI0080 5 COG3692 COG3692, Uncharacterized protein conserved in bacteria Function unknown 16272574 Common coaA pantothenate kinase HI0631 70 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 16273034 Common xylH D-xylose ABC transporter permease protein HI1109 110 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 16272519 Common - hypothetical protein HI0576 43 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 16273315 Common - plasmid RP4 TraN-related protein HI1407 22 COG2369 COG2369, Uncharacterized protein, homolog of phage Mu protein gp30 Function unknown 16272311 Common yfeA iron-chelated ABC transporter periplasmic-binding protein HI0362 180 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 16273644 Common - hypothetical protein HI1149m 64 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 30995357 Common - N-acetyl-D-glucosamine kinase HI0182 141 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 30995387 Common pepE peptidase E HI0587 36 COG3340 PepE, Peptidase E Amino acid transport and metabolism 16273497 Common lolB outer membrane lipoprotein LolB HI1607 36 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 16272086 Common - hypothetical protein HI0112 3 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 16272262 Common proC pyrroline-5-carboxylate reductase HI0307 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 16273245 Common ftsH cell division protein HI1335 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 16272499 Pathogen - hypothetical protein HI0555 1 COG3759 COG3759, Predicted membrane protein Function unknown 16272361 Common - 23S rRNA pseudouridylate synthase C HI0412 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 16272196 Common - hypothetical protein HI0234 4 None None None 16272907 Common aroQ 3-dehydroquinate dehydratase HI0970 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 16273568 Common - hypothetical protein HI1681 16 COG3110 COG3110, Uncharacterized protein conserved in bacteria Function unknown 16272218 Common - 3-deoxy-D-manno-octulosonic-acid kinase HI0260.1 20 COG0478 COG0478, RIO-like serine/threonine protein kinase fused to N-terminal HTH domain Signal transduction mechanisms 16273147 Common upp uracil phosphoribosyltransferase HI1228 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 16273393 Pathogen - hypothetical protein HI1492 2 None None None 16272168 Pathogen - hypothetical protein HI0205 1 None None None 16272657 Common nusG transcription antitermination protein NusG HI0717 215 COG0250 NusG, Transcription antiterminator Transcription 16272741 Common rpsM 30S ribosomal protein S13 HI0799 245 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 16272835 Common emrB multidrug resistance protein B HI0897 205 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 30995373 Common rne ribonuclease E HI0413 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 16272070 Pathogen - hypothetical protein HI0096 2 None None None 16273281 Common - desulfoviridin gamma subunit HI1371 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 16272298 Common napB periplasmic nitrate reductase HI0347 41 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 16272291 Common priA primosome assembly protein PriA HI0339 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 16273598 Common crr glucose-specific PTS system component HI1711 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 16272714 Common atoA acetate CoA-transferase beta subunit HI0773 94 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 16273128 Common - hypothetical protein HI1208 105 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 30995355 Common hitB iron(III) ABC transporter permease protein HI0098 196 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 16273386 Pathogen - hypothetical protein HI1482 1 None None None 16272357 Common yebM ABC transporter ATP-binding protein HI0408 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 16273336 Common trpB tryptophan synthase subunit beta HI1431 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 16272769 Common - YciI-like protein HI0828 66 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 16273064 Common murG N-acetylglucosaminyl transferase HI1138 210 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 16272957 Common tktA transketolase HI1023 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 16272887 Common - diaminobutyrate--2-oxoglutarate aminotransferase HI0949 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 16273524 Common purR purine nucleotide synthesis repressor HI1635 128 COG1609 PurR, Transcriptional regulators Transcription 30995412 Common - HIT-related protein HI0961 233 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 30995463 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase HI1634 151 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 16272202 Common - hypothetical protein HI0242 5 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 30995453 Common - N-acetylmuramoyl-L-alanine amidase HI1494 8 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 16272221 Common hxuB heme-hemopexin utilization protein B HI0263 66 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 16272105 Common rnhA ribonuclease H HI0138 174 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 30995382 Common - heptosyltransferase-like protein HI0523 53 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 16272109 Common nanA N-acetylneuraminate lyase HI0142 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 30995409 Common - rare lipoprotein B HI0922 22 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 16273125 Common - hypothetical protein HI1205 22 COG3092 COG3092, Uncharacterized protein conserved in bacteria Function unknown 16272880 Common - hypothetical protein HI0943 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 16273256 Common potB spermidine/putrescine ABC transporter membrane protein HI1346 213 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 16272113 Common - hypothetical protein HI0146 112 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 16272867 Pathogen - hypothetical protein HI0930 1 None None None 16272279 Common - hypothetical protein HI0326 4 COG3923 PriC, Primosomal replication protein N'' DNA replication, recombination, and repair 16273641 Common - ABC-type amino acid transport system permease component HI1079m 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 16273343 Common - hypothetical protein HI1436 32 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 16272984 Common - transcriptional regulator AraC family HI1052 142 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 16272853 Common - outer membrane protein HI0916 36 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 30995402 Common rplE 50S ribosomal protein L5 HI0790 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 16273050 Common talB transaldolase B HI1125 184 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 16272208 Common ssb single-strand DNA-binding protein HI0250 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 16272627 Common glpA sn-glycerol-3-phosphate dehydrogenase subunit A HI0685 162 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 16272818 Common - hypothetical protein HI0878 27 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 16272146 Common - formate transporter HI0181 101 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 16272487 Common groEL chaperonin GroEL HI0543 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 16272691 Common dapF diaminopimelate epimerase HI0750 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 16273224 Common pheT phenylalanyl-tRNA synthetase subunit beta HI1312 232 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 16272813 Common wbaP undecaprenyl-phosphate galactosephosphotransferase HI0872 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 16272620 Common tpiA triosephosphate isomerase HI0678 219 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 16272398 Common vapD virulence-associated protein D HI0450 6 COG3309 VapD, Uncharacterized virulence-associated protein D Function unknown 16273290 Common phoB phosphate regulon transcriptional regulatory protein HI1379 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 16272911 Common - hypothetical protein HI0974.1 17 COG3924 COG3924, Predicted membrane protein Function unknown 16272029 Common uxuA mannonate dehydratase HI0055 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 16272213 Common dapA dihydrodipicolinate synthase HI0255 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 16273297 Common trpG anthranilate synthase component II HI1388 235 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 16272365 Common thiD phosphomethylpyrimidine kinase HI0416 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 16272053 Common ppiB peptidyl-prolyl cis-trans isomerase B HI0079 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 16272698 Common gpmA phosphoglyceromutase HI0757 154 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 16272650 Common - hypothetical protein HI0710 7 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 16272434 Common gidB glucose-inhibited division protein B HI0486 164 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 30995426 Common - hypothetical protein HI1150 26 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 16272237 Common - transport protein HI0281 129 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16273042 Common comM competence protein HI1117 203 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 16272391 Common recR recombination protein RecR HI0443 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 16272231 Common rph ribonuclease PH HI0273 186 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 16273470 Common alr alanine racemase HI1575 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 16273069 Common ftsZ cell division protein FtsZ HI1143 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 16272708 Common - hypothetical protein HI0767 209 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 16272141 Common rluD 23S rRNA pseudouridine synthase D HI0176 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 16272150 Common adhC alcohol dehydrogenase class III HI0185 198 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 16273314 Common - hypothetical protein HI1406 10 None None None 16272639 Common - hypothetical protein HI0698 125 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 16272988 Common - type III restriction-modification system methyltransferase-like protein HI1056 122 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 16273235 Common fabA 3-hydroxydecanoyl-(acyl carrier protein) dehydratase HI1325 80 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 16272192 Common pnp polynucleotide phosphorylase/polyadenylase HI0229 242 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 16272085 Common bphH glutathione transferase HI0111 91 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 16272543 Common recA recombinase A HI0600 244 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 16272035 Common rec2 recombination protein HI0061 159 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 16273025 Common - hypothetical protein HI1099 4 None None None 16272061 Common thrC threonine synthase HI0087 186 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 16272851 Common tsf elongation factor Ts HI0914 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 16272828 Common purD phosphoribosylamine--glycine ligase HI0888 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 30995446 Common - hypothetical protein HI1395 26 COG4185 COG4185, Uncharacterized protein conserved in bacteria Function unknown 16272525 Common rpsL 30S ribosomal protein S12 HI0581 240 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 16272103 Common engA GTP-binding protein EngA HI0136 237 COG1160 COG1160, Predicted GTPases General function prediction only 16273580 Common modA molybdenum ABC transporter periplasmic-binding protein HI1693 152 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 16272256 Common - hemolysin HI0301 219 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 16273153 Common mgsA methylglyoxal synthase HI1234 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 30995434 Common sanA SanA HI1262 40 COG2949 SanA, Uncharacterized membrane protein Function unknown 30995432 Common dsbA thiol-disulfide interchange protein HI1215 40 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 16273562 Common moaC molybdenum cofactor biosynthesis protein C HI1675 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 16272918 Common fis DNA-binding protein Fis HI0980 97 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 16272833 Common acrB acriflavine resistance protein HI0895 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 16272507 Common asnA asparagine synthetase AsnA HI0564 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 16273543 Common - hypothetical protein HI1656 107 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 16272300 Common adk adenylate kinase HI0349 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 16272606 Common - hypothetical protein HI0665 58 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 16273433 Common fabB 3-oxoacyl-(acyl carrier protein) synthase I HI1533 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16272601 Common - ABC transporter ATP-binding protein HI0658 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 30995393 Common mdaB modulator of drug activity B HI0648 49 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 16273569 Common sohB predicted inner membrane peptidase HI1682 189 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 16272745 Common rplQ 50S ribosomal protein L17 HI0803 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 16273102 Common artP arginine transporter ATP-binding subunit HI1180 249 COG4161 ArtP, ABC-type arginine transport system, ATPase component Amino acid transport and metabolism 16272701 Common - hypothetical protein HI0760 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 16272663 Common trkH TRK system potassium uptake protein HI0723 120 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 16272923 Common dprA DNA processing chain A HI0985 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 16272468 Common fba fructose-bisphosphate aldolase HI0524 146 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 16272689 Common - glycerol-3-phosphate acyltransferase HI0748 48 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 16273365 Common - hypothetical protein HI1462 108 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 16271980 Common - hypothetical protein HI0004 191 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 16272894 Common - hypothetical protein HI0956 21 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 16272409 Common - hypothetical protein HI0461 20 COG2990 VirK, Uncharacterized protein conserved in bacteria Function unknown 16271987 Common rsmC 16S ribosomal RNA m2G1207 methyltransferase HI0012 155 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 16273012 Common - hypothetical protein HI1084 69 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 30995470 Common - lipopolysaccharide biosynthesis protein HI1700 24 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 16273412 Common - hypothetical protein HI1510 3 None None None 16272981 Common merT mercuric ion transport protein HI1049 10 None None None 16272805 Common glnA glutamine synthetase HI0865 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 16272307 Common - transcriptional activator HI0358 75 COG0819 TenA, Putative transcription activator Transcription 16273199 Common hsdR type I restriction enzyme HI1285 136 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 16272874 Common suhB extragenic suppressor HI0937 212 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 16272228 Common - hypothetical protein HI0270 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 16272776 Common frdA fumarate reductase flavoprotein subunit HI0835 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 16273130 Common mdh malate dehydrogenase HI1210 190 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 16272289 Common glnB nitrogen regulatory protein P-II HI0337 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 16273161 Common bcr bicyclomycin/multidrug efflux system HI1242 210 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 16272157 Common seqA replication initiation regulator SeqA HI0192 23 COG3057 SeqA, Negative regulator of replication initiationR DNA replication, recombination, and repair 16272130 Common bolA transcriptional regulator HI0163 84 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 16273450 Common bioD dithiobiotin synthetase HI1550 156 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 16273358 Common - hypothetical protein HI1452 49 COG2431 COG2431, Predicted membrane protein Function unknown 16272005 Common - lipoprotein HI0030 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 16272784 Common - hypothetical protein HI0843 4 None None None 16273475 Common - hypothetical protein HI1581 4 COG3102 COG3102, Uncharacterized protein conserved in bacteria Function unknown 16273189 Common - hydroxyacylglutathione hydrolase HI1274 164 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 16271992 Common - autonomous glycyl radical cofactor GrcA HI0017 52 COG3445 COG3445, Acid-induced glycyl radical enzyme General function prediction only 16273407 Common - hypothetical protein HI1505 17 COG4397 COG4397, Mu-like prophage major head subunit gpT General function prediction only 16272753 Common galU glucosephosphate uridylyltransferase HI0812 230 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 16272757 Common pepP aminopeptidase P HI0816 242 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 16273457 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase HI1557 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 16272946 Common - hypothetical protein HI1011 59 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 16272475 Common rpsU 30S ribosomal protein S21 HI0531 122 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 16273019 Common ccmC heme exporter protein C HI1091 125 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 16272938 Common trmE tRNA modification GTPase TrmE HI1002 232 COG0486 ThdF, Predicted GTPase General function prediction only 16273516 Common - hypothetical protein HI1627 92 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 16271999 Common citD citrate lyase subunit gamma HI0024 26 COG3052 CitD, Citrate lyase, gamma subunit Energy production and conversion 16272960 Common - putative L-xylulose 5-phosphate 3-epimerase HI1026 27 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 16273288 Common sbcB exonuclease I HI1377 51 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 16272094 Common ppa inorganic pyrophosphatase HI0124 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 16272569 Common mscL large conductance mechanosensitive channel HI0626 138 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 16272047 Common - nucleotidyltransferase HI0073 15 None None None 16272847 Common mutT mutator protein HI0910 146 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 30995440 Common asnC asparaginyl-tRNA synthetase HI1302 211 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 16272013 Common mreC rod shape-determining protein HI0038 141 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 16273522 Common purA adenylosuccinate synthetase HI1633 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 16272582 Common purB adenylosuccinate lyase HI0639 228 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 16272931 Common dnaA chromosomal replication initiation protein HI0993 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 16273112 Common - 6-pyruvoyl tetrahydrobiopterin synthase HI1190 126 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 16272535 Common speF ornithine decarboxylase HI0591 86 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 16273605 Common glnD PII uridylyl-transferase HI1719 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 16273009 Common murZ UDP-N-acetylglucosamine 1-carboxyvinyltransferase HI1081 217 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 16272920 Common pfkA 6-phosphofructokinase HI0982 160 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 16273194 Common neuA acylneuraminate cytidylyltransferase HI1279 66 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 18677785 Common rplS 50S ribosomal protein L19 HI0201 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 16272090 Common - hypothetical protein HI0120 6 COG5413 COG5413, Uncharacterized integral membrane protein Function unknown 16273553 Common - hypothetical protein HI1666 46 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 16272413 Common serA D-3-phosphoglycerate dehydrogenase HI0465 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 30995408 Common rffG dTDP-glucose 46-dehydratase HI0873 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 16272598 Common aroE shikimate 5-dehydrogenase HI0655 217 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 16272135 Common - Na(+)-translocating NADH-quinone reductase subunit E HI0170 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 16273254 Common potD spermidine/putrescine ABC transporter periplasmic-binding protein HI1344 138 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 16273429 Common parC DNA topoisomerase IV subunit A HI1529 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 16272044 Common recN DNA repair protein HI0070 209 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 16273002 Common - hypothetical protein HI1073 72 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 16272969 Common corA magnesium/nickel/cobalt transporter CorA HI1035 157 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 16272722 Common rpsS 30S ribosomal protein S19 HI0781 246 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 16273615 Common - hypothetical protein HI1730 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 16273372 Common rpsO 30S ribosomal protein S15 HI1468 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 16272883 Common fpg formamidopyrimidine-DNA glycosylase HI0946 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 16272885 Common vapC virulence-associated protein C HI0947 58 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 16272088 Common - hypothetical protein HI0118 178 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 16272497 Common gnd 6-phosphogluconate dehydrogenase HI0553 181 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 16272909 Common accC acetyl-CoA carboxylase biotin carboxylase subunit HI0972 234 COG0439 AccC, Biotin carboxylase Lipid metabolism 16272355 Common accA acetyl-CoA carboxylase carboxyltransferase subunit alpha HI0406 209 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 16273039 Common rfaD ADP-L-glycero-D-mannoheptose-6-epimerase HI1114 226 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 16273177 Common - periplasmic serine protease HI1259 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 16272659 Common - hypothetical protein HI0719 184 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 30995456 Common htrB lipid A biosynthesis lauroyl acyltransferase HI1527 82 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 16272526 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA HI0582 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 16273149 Common apt adenine phosphoribosyltransferase HI1230 190 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 16272845 Common - hypothetical protein HI0908 4 None None None 16273243 Common yhbY hypothetical protein HI1333 97 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 16273322 Common - hypothetical protein HI1415 29 COG3179 COG3179, Predicted chitinase General function prediction only 16272100 Common dcd deoxycytidine triphosphate deaminase HI0133 158 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 16272240 Common menF menaquinone-specific isochorismate synthase HI0285 221 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 16273391 Common - E16 protein HI1488 13 COG4382 COG4382, Mu-like prophage protein gp16 Function unknown 16272511 Common tex transcription accessory protein HI0568 214 COG2183 Tex, Transcriptional accessory protein Transcription 16273267 Common glgB glycogen branching enzyme HI1357 148 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 16272359 Common tyrR transcriptional regulatory protein HI0410 171 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 16272293 Common - hypothetical protein HI0341 23 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 16272996 Common pyrH uridylate kinase HI1065 242 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 16272439 Common - hypothetical protein HI0493 72 None None None 16273388 Pathogen - hypothetical protein HI1485 1 None None None 16272374 Common fadR fatty acid metabolism regulator HI0426 57 COG2186 FadR, Transcriptional regulators Transcription 30995389 Common fucI L-fucose isomerase HI0614 19 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 16273082 Common cydD cysteine/glutathione ABC transporter membrane/ATP-binding component HI1157 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 16273286 Common - hypothetical protein HI1375 24 COG3586 COG3586, Uncharacterized conserved protein Function unknown 16272092 Common metC cystathionine beta-lyase HI0122 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 16273519 Common rpL25 50S ribosomal protein L25 HI1630 148 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 16273531 Common sapF peptide ABC transporter ATP-binding protein HI1642 249 COG4167 SapF, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 16272385 Common comC competence protein C HI0437 3 None None None 16272183 Common guaB inositol-5-monophosphate dehydrogenase HI0221 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 16273655 Common cmk cytidylate kinase HI1646m 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 16273464 Common - hypothetical protein HI1564 4 None None None 16272572 Common mclA sigma-E factor negative regulatory protein HI0629 20 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 16273469 Common dnaB replicative DNA helicase HI1574 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 16272936 Common - hypothetical protein HI1000 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 16273462 Pathogen - hypothetical protein HI1562 1 None None None 16272120 Common - hypothetical protein HI0152 17 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 16272477 Common rpoD RNA polymerase sigma-70 factor HI0533 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 16273074 Common - ABC transporter ATP-binding protein HI1148 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 16272233 Common - hypothetical protein HI0275 28 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 16272795 Common - hypothetical protein HI0855 33 COG3681 COG3681, Uncharacterized conserved protein Function unknown 16272448 Common rbsB D-ribose transporter subunit RbsB HI0504 126 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 16273036 Common xylF D-xylose transporter subunit XylF HI1111 103 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 30995423 Common - amino acid ABC transporter ATP-binding protein HI1078 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 16273279 Common - hypothetical protein HI1369 15 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 16273499 Common prsA ribose-phosphate pyrophosphokinase HI1609 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 16272441 Common hslU ATP-dependent protease ATP-binding subunit HI0497 212 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 16272617 Common pepD aminoacyl-histidine dipeptidase HI0675 65 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 30995359 Common rimM 16S rRNA-processing protein HI0203 137 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 16273418 Common - hypothetical protein HI1518 18 COG4384 COG4384, Mu-like prophage protein gp45 Function unknown 16272630 Pathogen - hypothetical protein HI0688 1 None None None 16272622 Common - RarD HI0680 94 COG2962 RarD, Predicted permeases General function prediction only 16272282 Common oapA opacity associated protein HI0330 12 COG3061 OapA, Cell envelope opacity-associated protein A Cell envelope biogenesis, outer membrane 16273575 Common - SoxR-reducing system protein RsxE HI1688 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 30995418 Common - hypothetical protein HI1036 67 COG0762 COG0762, Predicted integral membrane protein Function unknown 16272341 Common - O-antigen acetylase HI0392 90 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 16272396 Common fruB fructose-specific PTS IIA/HPr components HI0448 123 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 16272211 Common exbB biopolymer transport protein HI0253 20 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 16272432 Common atpB F0F1 ATP synthase subunit A HI0485 206 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 16273222 Pathogen - hypothetical protein HI1310 2 None None None 16272643 Common surE stationary phase survival protein SurE HI0702 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 16272652 Common - hemoglobin-binding protein HI0712 43 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 16272402 Common - hypothetical protein HI0454 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 16272051 Common - hypothetical protein HI0077 47 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 16273238 Common rpsO 30S ribosomal protein S15 HI1328 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 16272334 Common - hypothetical protein HI0386 121 COG0824 FcbC, Predicted thioesterase General function prediction only 16272629 Common - hypothetical protein HI0687 5 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 16272986 Common - hypothetical protein HI1054 8 COG3421 COG3421, Uncharacterized protein conserved in bacteria Function unknown 16273048 Common oppB oligopeptide transporter permease HI1123 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 16273067 Common ftsQ cell division protein HI1141 68 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 16272680 Common ilvA threonine dehydratase HI0738.1 219 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 16272190 Common - hypothetical protein HI0227 30 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 30995460 Common - hypothetical protein HI1602 19 COG2259 COG2259, Predicted membrane protein Function unknown 16272371 Common - hypothetical protein HI0423 89 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 16272423 Common hisIE phosphoribosyl-AMP cyclohydrolase/phosphoribosyl-ATP pyrophosphohydrolase HI0475 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 30995410 Common - hypothetical protein HI0931 6 COG4316 COG4316, Uncharacterized protein conserved in bacteria Function unknown 16273040 Common - thioredoxin HI1115 63 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 16272411 Common - coproporphyrinogen III oxidase HI0463 207 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 16273062 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase HI1136 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 16272033 Common lpxK tetraacyldisaccharide 4'-kinase HI0059 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 16272247 Common merP mercuric ion scavenger protein HI0292 50 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 30995455 Common - hypothetical protein HI1521 14 COG3778 COG3778, Uncharacterized protein conserved in bacteria Function unknown 16273018 Common ccmB heme exporter protein B HI1090 82 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 16272916 Common prmA ribosomal protein L11 methyltransferase HI0978 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 30995477 Common spoT guanosine-3'5'-bis(diphosphate) 3'- pyrophosphohydrolase HI1741 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 16272277 Common rnt ribonuclease T HI0324 47 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 16273168 Common - hypothetical protein HI1249 29 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 16272206 Common - hypothetical protein HI0246 2 None None None 16272238 Common - acyl-CoA thioester hydrolase YfbB HI0282 56 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 16272107 Common nagA N-acetylglucosamine-6-phosphate deacetylase HI0140 119 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 16272020 Common - hypothetical protein HI0045 18 COG3054 COG3054, Predicted transcriptional regulator General function prediction only 16272267 Common ruvA Holliday junction DNA helicase motor protein HI0313 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 16272260 Common - Holliday junction resolvase-like protein HI0305 153 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 16273113 Common - hypothetical protein HI1191 171 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 30995361 Common prlC oligopeptidase A HI0214 126 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 16272201 Common yajC preprotein translocase subunit YajC HI0241 165 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 161350014 Common efp elongation factor P HI0328 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 16273642 Common ccmH cytochrome C-type biogenesis protein HI1096m 90 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 16273638 Common coaE dephospho-CoA kinase HI0890m 204 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism