Thermoanaerobacter pseudethanolicus ATCC 33223, complete genome NC_010321 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 167038006 Nonpathogen - hypothetical protein Teth39_1604 2 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 167037881 Common - dephospho-CoA kinase Teth39_1473 210 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 167037614 Common - polysaccharide deacetylase Teth39_1202 148 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 167038362 Common - penicillin-binding protein, 1A family Teth39_1978 206 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 167037801 Common - chaperone protein DnaJ Teth39_1392 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 167036801 Common - ribosomal protein L3 Teth39_0374 247 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 167037958 Common - lipopolysaccharide biosynthesis protein Teth39_1555 79 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 167036516 Common - hypothetical protein Teth39_0085 6 None None None 167037861 Common - DNA repair protein RadC Teth39_1453 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 167037348 Common - transposase, IS4 family protein Teth39_0935 8 None None None 167037786 Common - MiaB-like tRNA modifying enzyme Teth39_1376 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 167036609 Nonpathogen - Molybdopterin-guanine dinucleotide biosynthesis protein A-like protein Teth39_0178 23 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 167036602 Common - transcriptional regulator, AbrB family Teth39_0171 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 167037406 Common - cytochrome c biogenesis protein, transmembrane region Teth39_0993 165 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 167037312 Nonpathogen - hypothetical protein Teth39_0898 11 None None None 167038031 Common - glycosyl transferase, family 2 Teth39_1631 111 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 167037330 Common - CRISPR-associated protein, TM1812 family Teth39_0917 17 None None None 167037340 Common - DNA methylase N-4/N-6 domain protein Teth39_0927 22 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 167036831 Common - ABC transporter related Teth39_0404 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 167036445 Common - ketol-acid reductoisomerase Teth39_0014 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 167037819 Nonpathogen - hypothetical protein Teth39_1410 1 None None None 167036772 Common - PilT protein domain protein Teth39_0345 44 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 167037951 Nonpathogen - hypothetical protein Teth39_1548 2 None None None 167037339 Common - hypothetical protein Teth39_0926 13 COG2433 COG2433, Uncharacterized conserved protein Function unknown 167037687 Common - RNA-binding protein (contains KH domain)-like protein Teth39_1275 70 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 167036735 Common - membrane protein-like protein Teth39_0308 13 COG4684 COG4684, Predicted membrane protein Function unknown 167036937 Common - Histidine--tRNA ligase Teth39_0514 249 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 167037676 Common - DNA topoisomerase I Teth39_1264 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 167037891 Common - DNA polymerase, beta domain protein region Teth39_1483 18 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 167037500 Common - hypothetical protein Teth39_1087 10 None None None 167038455 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Teth39_2073 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 167037005 Nonpathogen - hypothetical protein Teth39_0583 1 None None None 167037063 Common - Cobyrinic acid a,c-diamide synthase Teth39_0641 48 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 167037465 Common - alanyl-tRNA synthetase Teth39_1052 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167038048 Common - ATP-dependent protease La Teth39_1649 212 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 167036661 Common - calcium-translocating P-type ATPase, PMCA-type Teth39_0231 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 167036567 Common - NADH:flavin oxidoreductase/NADH oxidase Teth39_0136 221 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 167037855 Common - septum site-determining protein MinD Teth39_1447 172 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 167038369 Common - OsmC family protein Teth39_1985 48 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 167036434 Common - RNA-binding S4 domain protein Teth39_0003 50 COG2501 COG2501, Uncharacterized conserved protein Function unknown 167036793 Common - DNA-directed RNA polymerase, beta subunit Teth39_0366 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 167038442 Common - xylose isomerase Teth39_2060 69 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 167037822 Common - branched-chain amino acid aminotransferase Teth39_1413 210 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 167038482 Common - hypothetical protein Teth39_2101 7 None None None 167038363 Common - iron-containing alcohol dehydrogenase Teth39_1979 169 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 167036722 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Teth39_0295 52 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 167037284 Nonpathogen - protein of unknown function YGGT Teth39_0870 3 None None None 167036788 Common - NusG antitermination factor Teth39_0361 215 COG0250 NusG, Transcription antiterminator Transcription 167036491 Common - Type IV secretory pathway VirB4 components-like protein Teth39_0060 67 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 167037946 Common - phosphoesterase, PA-phosphatase related Teth39_1543 28 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 167037011 Common - oxidoreductase domain protein Teth39_0589 190 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 167036570 Common - ACT domain-containing protein-like protein Teth39_0139 14 COG4492 PheB, ACT domain-containing protein General function prediction only 167038477 Common - peptidase M23B Teth39_2096 170 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 167036577 Common - histidinol phosphate phosphatase HisJ family Teth39_0146 37 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 167037733 Common - primosomal protein N' Teth39_1321 212 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 167037876 Common - GTP-binding protein TypA Teth39_1468 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 167036943 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Teth39_0520 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 167038240 Common - transposase, putative Teth39_1846 8 None None None 167037634 Common - ribosome recycling factor Teth39_1222 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 167036898 Common - protein of unknown function UPF0047 Teth39_0474 140 COG0432 COG0432, Uncharacterized conserved protein Function unknown 167038191 Common - two component transcriptional regulator, winged helix family Teth39_1796 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 167036953 Nonpathogen - hypothetical protein Teth39_0530 1 None None None 167036783 Common - protein of unknown function DUF901 Teth39_0356 31 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 167038087 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Teth39_1692 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 167036729 Common - PAS/PAC sensor signal transduction histidine kinase Teth39_0302 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 167037943 Common - ExsB family protein Teth39_1540 75 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 167036922 Common - thiamine biosynthesis protein ThiC Teth39_0498 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 167038655 Common - protein of unknown function DUF951 Teth39_2276 28 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 167036498 Nonpathogen - hypothetical protein Teth39_0067 2 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 167037167 Common - dipeptidase, putative Teth39_0750 155 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 167038404 Common - cobalamin (vitamin B12) biosynthesis CbiM protein Teth39_2020 88 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 167036824 Common - translation initiation factor IF-1 Teth39_0397 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 167038213 Common - putative aconitate hydratase Teth39_1819 223 COG1048 AcnA, Aconitase A Energy production and conversion 167036901 Common - Peptidoglycan-binding domain 1 protein Teth39_0477 66 COG2367 PenP, Beta-lactamase class A Defense mechanisms 167037236 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG family Teth39_0821 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 167036517 Nonpathogen - hypothetical protein Teth39_0086 1 None None None 167038386 Common - hypothetical protein Teth39_2002 56 COG3281 Ble, Uncharacterized protein, probably involved in trehalose biosynthesis Carbohydrate transport and metabolism 167038069 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Teth39_1674 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 167037556 Common - spermidine synthase Teth39_1143 129 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 167038170 Common - putative RNA methylase Teth39_1775 59 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 167037223 Common - UDP-N-acetylmuramyl-tripeptide synthetase Teth39_0808 215 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 167036988 Common - carboxyl-terminal protease Teth39_0566 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 167038570 Common - short-chain dehydrogenase/reductase SDR Teth39_2190 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 167036694 Common - transposase IS3/IS911 family protein Teth39_0267 34 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 167038196 Common - major facilitator superfamily MFS_1 Teth39_1801 94 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 167038449 Common - PTS system sorbose subfamily IIB component Teth39_2067 38 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 167037843 Common - ribosomal protein L21 Teth39_1435 215 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 167038084 Common - extracellular solute-binding protein, family 5 Teth39_1689 212 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 167037007 Nonpathogen - hypothetical protein Teth39_0585 5 None None None 167038341 Common - Indigoidine synthase A family protein Teth39_1952 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 167037488 Nonpathogen - hypothetical protein Teth39_1075 1 COG4726 PilX, Tfp pilus assembly protein PilX Cell motility and secretion / Intracellular trafficking and secretion 167037509 Common - protein of unknown function DUF322 Teth39_1096 43 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 167038395 Common - ATP-dependent nuclease subunit B-like protein Teth39_2011 32 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 167037684 Common - ribosomal protein L19 Teth39_1272 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 167037572 Common - urea amidolyase related protein Teth39_1159 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 167036584 Common - PTS system, fructose subfamily, IIC subunit Teth39_0153 69 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 167038558 Common - glycosyl transferase, group 1 Teth39_2178 83 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 167036790 Common - ribosomal protein L1 Teth39_0363 247 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 167037305 Common - Indole-3-glycerol-phosphate synthase Teth39_0891 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 167037052 Common - Integrase, catalytic region Teth39_0630 55 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 167038233 Common - transposase, IS4 family protein Teth39_1839 9 None None None 167037059 Common - Methyltransferase type 11 Teth39_0637 78 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 167037473 Common - aminodeoxychorismate lyase Teth39_1060 186 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 167037604 Common - competence/damage-inducible protein CinA Teth39_1192 214 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 167038289 Common - hypothetical protein Teth39_1898 10 None None None 167037758 Nonpathogen - hypothetical protein Teth39_1346 1 None None None 167038348 Common - hypothetical protein Teth39_1959 5 None None None 167036619 Common - hypothetical protein Teth39_0188 14 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 167036593 Common - ribose-phosphate pyrophosphokinase Teth39_0162 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 167038544 Common - protein of unknown function DUF917 Teth39_2164 35 COG3535 COG3535, Uncharacterized conserved protein Function unknown 167037668 Common - flagellar motor switch protein FliG Teth39_1256 126 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 167038148 Common - RNA binding S1 domain protein Teth39_1753 218 COG2183 Tex, Transcriptional accessory protein Transcription 167036612 Common - spore germination protein Teth39_0181 20 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 167037219 Common - MraZ protein Teth39_0804 143 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 167038673 Common - ribonuclease P protein component Teth39_2294 71 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 167036506 Common - Peptidoglycan-binding domain 1 protein Teth39_0075 28 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 167037438 Common - 2-polyprenylphenol 6-hydroxylase Teth39_1025 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 167036533 Nonpathogen - hypothetical protein Teth39_0102 13 None None None 167037560 Nonpathogen - hypothetical protein Teth39_1147 5 None None None 167037708 Common - phosphate acetyltransferase Teth39_1296 163 COG0280 Pta, Phosphotransacetylase Energy production and conversion 167037199 Common - hypothetical protein Teth39_0784 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 167038245 Common - transcriptional regulator, GntR family Teth39_1852 90 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 167036799 Common - translation elongation factor Tu Teth39_0372 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 167037259 Common - 2-hydroxyglutaryl-CoA dehydratase, D-component Teth39_0844 21 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 167037162 Common - sodium/hydrogen exchanger Teth39_0745 198 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 167038433 Common - transposase, IS605 OrfB family Teth39_2051 30 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 167038394 Common - UvrD-like DNA helicase, C terminal Teth39_2010 228 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 167038379 Nonpathogen - Dehydrogenase (flavoprotein)-like protein Teth39_1995 13 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 167037426 Common - Holliday junction DNA helicase RuvA Teth39_1013 212 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 167037776 Common - diacylglycerol kinase Teth39_1366 59 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 167038629 Common - methyl-accepting chemotaxis sensory transducer Teth39_2250 131 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 167037799 Common - hypothetical protein Teth39_1389 8 None None None 167037026 Common - UDP-glucose 4-epimerase Teth39_0604 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 167036653 Common - N-acetyl-gamma-glutamyl-phosphate reductase Teth39_0223 219 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 167037000 Common - putative glucokinase, ROK family Teth39_0578 176 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 167038579 Common - conserved hypothetical protein 103 Teth39_2199 170 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 167038620 Nonpathogen - hypothetical protein Teth39_2241 2 None None None 167036547 Common - FeS assembly ATPase SufC Teth39_0116 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 167036553 Nonpathogen - CRISPR-associated protein, TM1802 family Teth39_0122 13 None None None 167038596 Nonpathogen - hypothetical protein Teth39_2217 4 None None None 167038532 Common - Orn/Lys/Arg decarboxylase, major region Teth39_2151 101 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 167037715 Common - small acid-soluble spore protein, alpha/beta type Teth39_1303 14 None None None 167036913 Common - transcriptional modulator of MazE/toxin, MazF Teth39_0489 66 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 167038645 Common - uracil-xanthine permease Teth39_2266 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 167037369 Nonpathogen - hypothetical protein Teth39_0956 1 None None None 167038252 Nonpathogen - hypothetical protein Teth39_1860 2 None None None 167037186 Common - ribosomal protein L20 Teth39_0769 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 167036685 Common - RNA binding S1 domain protein Teth39_0258 241 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 167037396 Common - Prephenate dehydratase Teth39_0983 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 167038372 Common - glycine cleavage system T protein Teth39_1988 183 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 167037810 Common - Stage II sporulation P family protein Teth39_1401 15 None None None 167037739 Common - Diaminopimelate epimerase Teth39_1327 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 167036854 Nonpathogen - Desulfoferrodoxin, ferrous iron-binding region Teth39_0429 20 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 167036754 Common - aminotransferase class-III Teth39_0327 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 167038512 Nonpathogen - hypothetical protein Teth39_2131 2 None None None 167038154 Nonpathogen - hypothetical protein Teth39_1759 8 None None None 167038238 Common - protein of unknown function DUF125, transmembrane Teth39_1844 68 COG1814 COG1814, Uncharacterized membrane protein Function unknown 167038509 Common - protein of unknown function DUF59 Teth39_2128 232 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 167037102 Common - DNA polymerase III, alpha subunit Teth39_0681 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 167038500 Common - electron transport complex, RnfABCDGE type, B subunit Teth39_2119 146 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 167038304 Common - nitrite and sulphite reductase 4Fe-4S region Teth39_1915 99 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 167038229 Common - imidazolonepropionase Teth39_1835 134 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 167038025 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Teth39_1625 169 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 167037743 Common - 2'-5' RNA ligase Teth39_1331 102 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 167037970 Common - hypothetical protein Teth39_1567 13 None None None 167037268 Common - molybdopterin-guanine dinucleotide biosynthesis protein B Teth39_0854 97 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 167036736 Common - putative transcriptional acitvator, Baf family Teth39_0309 136 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 167036489 Common - AAA ATPase Teth39_0058 70 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 167036456 Common - protein of unknown function UPF0118 Teth39_0025 178 COG0628 PerM, Predicted permease General function prediction only 167038622 Nonpathogen - transcriptional regulator, XRE family Teth39_2243 1 COG1476 COG1476, Predicted transcriptional regulators Transcription 167037085 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Teth39_0664 207 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 167036805 Common - ribosomal protein S19 Teth39_0378 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 167038106 Common - phosphoribosylformylglycinamidine cyclo-ligase Teth39_1711 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 167037913 Common - single-strand binding protein/Primosomal replication protein n Teth39_1506 7 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 167037041 Common - sodium:neurotransmitter symporter Teth39_0619 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 167037415 Common - hypothetical protein Teth39_1002 9 None None None 167037407 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Teth39_0994 156 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 167038411 Common - aminotransferase, class I and II Teth39_2027 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 167038220 Common - pyrimidine-nucleoside phosphorylase Teth39_1826 124 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 167037490 Common - Tfp pilus assembly protein ATPase PilM-like protein Teth39_1077 70 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 167037367 Common - protein of unknown function DUF979 Teth39_0954 29 COG3817 COG3817, Predicted membrane protein Function unknown 167037459 Common - alanine racemase domain protein Teth39_1046 18 COG3457 COG3457, Predicted amino acid racemase Amino acid transport and metabolism 167036687 Common - ROK family protein Teth39_0260 171 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 167037962 Common - SNO glutamine amidotransferase Teth39_1559 91 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 167037130 Nonpathogen - hypothetical protein Teth39_0712 1 None None None 167038111 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Teth39_1716 217 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 167037900 Common - transcriptional regulator, GntR family with aminotransferase domain Teth39_1493 216 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 167038639 Common - Vacuolar H+-transporting two-sector ATPase, F subunit Teth39_2260 10 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 167038327 Common - 5'-nucleotidase., 2',3'-cyclic-nucleotide 2'-phosphodiesterase Teth39_1938 142 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 167037656 Common - CheC, inhibitor of MCP methylation / FliN fusion protein Teth39_1244 131 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 167036496 Common - type II secretion system protein E Teth39_0065 216 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 167037565 Common - pyruvate/ketoisovalerate oxidoreductase, gamma subunit Teth39_1152 45 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 167037654 Common - hypothetical protein Teth39_1242 6 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 167036664 Common - Ferritin, Dps family protein Teth39_0234 85 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 167038323 Common - transcriptional regulator, LacI family Teth39_1934 129 COG1609 PurR, Transcriptional regulators Transcription 167037586 Common - DNA mismatch repair protein MutS Teth39_1174 207 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 167038300 Common - protein of unknown function DUF477 Teth39_1909 83 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 167036477 Nonpathogen - hypothetical protein Teth39_0046 1 None None None 167036523 Nonpathogen - hypothetical protein Teth39_0092 1 None None None 167036470 Common - hypothetical protein Teth39_0039 5 None None None 167037990 Common - protein of unknown function UPF0027 Teth39_1588 121 COG1690 RtcB, Uncharacterized conserved protein Function unknown 167037196 Common - peptidase M18, aminopeptidase I Teth39_0781 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 167037486 Nonpathogen - hypothetical protein Teth39_1073 2 COG4967 PilV, Tfp pilus assembly protein PilV Cell motility and secretion / Intracellular trafficking and secretion 167038602 Common - type II secretion system protein Teth39_2223 19 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 167038496 Common - fructose-1,6-bisphosphate aldolase, class II Teth39_2115 178 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 167037135 Nonpathogen - hypothetical protein Teth39_0717 2 None None None 167036462 Nonpathogen - phospholipase D/Transphosphatidylase Teth39_0031 2 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 167038609 Nonpathogen - hypothetical protein Teth39_2230 1 None None None 167037760 Common - AIR synthase related protein domain protein Teth39_1348 208 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 167037115 Common - alpha-glucan phosphorylase Teth39_0695 147 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 167037240 Common - two component transcriptional regulator, winged helix family Teth39_0825 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 167037863 Nonpathogen - hypothetical protein Teth39_1455 1 None None None 167036982 Nonpathogen - hypothetical protein Teth39_0560 4 None None None 167037544 Common - protein of unknown function DUF1002 Teth39_1131 13 COG4086 COG4086, Predicted secreted protein Function unknown 167036713 Common - hypothetical protein Teth39_0286 5 None None None 167037452 Common - thioredoxin Teth39_1039 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 167037201 Common - lipoate-protein ligase B Teth39_0786 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 167038050 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Teth39_1651 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 167036671 Common - fumarate lyase Teth39_0244 236 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 167037920 Common - binding-protein-dependent transport systems inner membrane component Teth39_1515 203 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 167037124 Common - Patatin Teth39_0705 56 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 167038164 Nonpathogen - hypothetical protein Teth39_1769 2 None None None 167037170 Common - putative GAF sensor protein Teth39_0753 80 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 167038073 Common - SAF domain Teth39_1678 67 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 167037013 Common - Xylose isomerase domain protein TIM barrel Teth39_0591 55 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 167037553 Common - glucose-inhibited division protein A Teth39_1140 17 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 167038480 Common - alanine dehydrogenase Teth39_2099 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 167038120 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Teth39_1725 122 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 167036993 Common - FHA domain containing protein Teth39_0571 70 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 167038423 Common - ABC transporter related Teth39_2040 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 167037999 Common - iron-containing alcohol dehydrogenase Teth39_1597 172 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 167037444 Common - protein of unknown function DUF214 Teth39_1031 179 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 167036704 Common - transcriptional regulator, ArsR family Teth39_0277 181 COG0640 ArsR, Predicted transcriptional regulators Transcription 167036603 Common - peptidase U57, YabG Teth39_0172 11 None None None 167037032 Common - glycoside hydrolase, clan GH-D Teth39_0610 45 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 167037414 Common - small GTP-binding protein Teth39_1001 240 COG2262 HflX, GTPases General function prediction only 167037532 Common - Serine-type D-Ala-D-Ala carboxypeptidase Teth39_1119 157 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 167038387 Common - galactose-1-phosphate uridylyltransferase Teth39_2003 83 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 167038131 Common - hypothetical protein Teth39_1736 6 None None None 167037835 Common - iojap-like protein Teth39_1427 201 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 167036931 Common - ABC-2 type transporter Teth39_0507 75 None None None 167037140 Common - peptidase S16, lon domain protein Teth39_0722 124 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 167038337 Common - PTS system, lactose/cellobiose family IIC subunit Teth39_1948 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 167038470 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Teth39_2089 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 167037353 Common - hypothetical protein Teth39_0940 5 None None None 167036866 Common - thymidylate synthase complementing protein ThyX Teth39_0441 31 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 167038263 Nonpathogen - hypothetical protein Teth39_1871 5 None None None 167037149 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Teth39_0731 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 167036967 Common - dihydroxyacetone kinase, phosphotransfer subunit Teth39_0544 45 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 167036647 Common - oxidoreductase FAD/NAD(P)-binding domain protein Teth39_0217 81 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 167037909 Common - dihydrodipicolinate synthase Teth39_1502 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 167038582 Common - CMP/dCMP deaminase, zinc-binding Teth39_2202 221 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 167038299 Common - protein of unknown function DUF820 Teth39_1908 37 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 167036891 Common - thiamine pyrophosphate enzyme domain protein TPP-binding Teth39_0466 110 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 167037497 Common - 3-dehydroquinate dehydratase, type II Teth39_1084 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 167037386 Common - arsenate reductase Teth39_0973 148 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 167038630 Nonpathogen - hypothetical protein Teth39_2251 1 COG4317 COG4317, Uncharacterized protein conserved in bacteria Function unknown 167037202 Common - lipoic acid synthetase Teth39_0787 197 COG0320 LipA, Lipoate synthase Coenzyme metabolism 167038091 Common - TrpR like protein, YerC/YecD Teth39_1696 21 COG4496 COG4496, Uncharacterized protein conserved in bacteria Function unknown 167037689 Common - signal recognition particle protein Teth39_1277 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 167038489 Common - zinc/iron permease Teth39_2108 106 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 167038200 Common - tRNA(1-methyladenosine) methyltransferase and related methyltransferase-like protein Teth39_1806 64 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 167038660 Common - diacylglycerol kinase, catalytic region Teth39_2281 116 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 167038322 Common - extracellular solute-binding protein, family 5 Teth39_1933 200 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 167038282 Common - Porphobilinogen deaminase Teth39_1891 219 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 167036447 Common - 3-isopropylmalate dehydratase, large subunit Teth39_0016 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 167037410 Common - transposase IS116/IS110/IS902 family protein Teth39_0997 66 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 167038549 Common - phage SPO1 DNA polymerase-related protein Teth39_2169 153 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 167037045 Common - Peptidoglycan glycosyltransferase Teth39_0623 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 167036742 Nonpathogen - hypothetical protein Teth39_0315 19 None None None 167038555 Common - short-chain dehydrogenase/reductase SDR Teth39_2175 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 167037177 Common - response regulator receiver modulated diguanylate cyclase Teth39_0760 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 167038613 Nonpathogen - hypothetical protein Teth39_2234 1 None None None 167036566 Common - CRISPR-associated protein Cas2 Teth39_0135 45 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 167037296 Common - purine phosphorylase, family 2 Teth39_0882 168 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 167037914 Common - Mur ligase, middle domain protein Teth39_1507 5 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 167037272 Common - molybdenum cofactor synthesis domain Teth39_0858 188 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 167037364 Common - ABC transporter related Teth39_0951 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 167036559 Common - transposase IS116/IS110/IS902 family protein Teth39_0128 99 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 167038156 Nonpathogen - hypothetical protein Teth39_1761 9 None None None 167037937 Common - BioY protein Teth39_1532 107 COG1268 BioY, Uncharacterized conserved protein General function prediction only 167038367 Common - transcriptional antiterminator, BglG Teth39_1983 53 COG3711 BglG, Transcriptional antiterminator Transcription 167037471 Common - protein of unknown function DUF964 Teth39_1058 18 COG3679 COG3679, Uncharacterized conserved protein Function unknown 167037857 Common - penicillin-binding protein, transpeptidase Teth39_1449 206 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 167037766 Common - ribonuclease R Teth39_1356 193 COG0557 VacB, Exoribonuclease R Transcription 167036696 Common - transposase, mutator type Teth39_0269 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 167038353 Nonpathogen - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Teth39_1967 25 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 167038453 Common - PTS system transcriptional activator Teth39_2071 161 COG3933 COG3933, Transcriptional antiterminator Transcription 167038000 Common - aldo/keto reductase Teth39_1598 203 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 167036795 Common - ribosomal protein L7Ae/L30e/S12e/Gadd45 Teth39_0368 16 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 167038046 Common - protein of unknown function DUF6, transmembrane Teth39_1647 116 None None None 167037251 Nonpathogen - hypothetical protein Teth39_0836 1 None None None 167037824 Nonpathogen - hypothetical protein Teth39_1416 5 None None None 167036929 Common - glycosyltransferase 36 associated Teth39_0505 47 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 167036508 Common - metal dependent phosphohydrolase Teth39_0077 123 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 167038392 Common - SMC domain protein Teth39_2008 149 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 167036884 Common - acetate and butyrate kinase Teth39_0459 72 COG3426 COG3426, Butyrate kinase Energy production and conversion 167036974 Common - putative CoA-substrate-specific enzyme activase Teth39_0552 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 167036784 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Teth39_0357 100 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 167038089 Common - DNA ligase, NAD-dependent Teth39_1694 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 167036484 Nonpathogen - hypothetical protein Teth39_0053 1 None None None 167036762 Common - phosphoenolpyruvate-protein phosphotransferase Teth39_0335 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 167038657 Common - protein of unknown function DUF1256 Teth39_2278 14 None None None 167036905 Common - transcriptional regulator, XRE family Teth39_0481 23 COG1395 COG1395, Predicted transcriptional regulator Transcription 167037742 Common - Fibronectin-binding A domain protein Teth39_1330 91 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 167036924 Common - Homoserine dehydrogenase Teth39_0500 216 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 167037589 Common - RNA chaperone Hfq Teth39_1177 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 167036716 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Teth39_0289 117 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 167036691 Common - Dextranase Teth39_0264 6 None None None 167036769 Common - ATPase AAA-2 domain protein Teth39_0342 218 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 167036538 Common - protein of unknown function DUF163 Teth39_0107 13 COG1576 COG1576, Uncharacterized conserved protein Function unknown 167038650 Common - hypothetical protein Teth39_2271 7 COG4241 COG4241, Predicted membrane protein Function unknown 167038537 Common - protein of unknown function DUF395, YeeE/YedE Teth39_2156 70 None None None 167036569 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_0138 100 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167036600 Common - transcription-repair coupling factor Teth39_0169 243 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 167036941 Common - Imidazoleglycerol-phosphate dehydratase Teth39_0518 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 167036878 Common - protein of unknown function DUF58 Teth39_0453 35 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 167038193 Common - Cof-like hydrolase Teth39_1798 142 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 167037225 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Teth39_0810 226 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 167036803 Common - Ribosomal protein L25/L23 Teth39_0376 224 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 167037590 Common - pyrroline-5-carboxylate reductase Teth39_1178 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 167036871 Common - Peptidoglycan-binding domain 1 protein Teth39_0446 112 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 167038008 Common - hypothetical protein Teth39_1606 12 None None None 167038530 Common - protein of unknown function DUF970 Teth39_2149 20 COG3870 COG3870, Uncharacterized protein conserved in bacteria Function unknown 167038059 Common - Glutamate synthase (NADPH) Teth39_1660 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 167038384 Common - hypothetical protein Teth39_2000 146 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 167037699 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Teth39_1287 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 167037244 Common - phosphate ABC transporter, inner membrane subunit PstA Teth39_0829 230 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 167038204 Common - aspartate 1-decarboxylase Teth39_1810 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 167036607 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Teth39_0176 190 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 167036774 Common - PGAP1 family protein Teth39_0347 8 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 167037702 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III Teth39_1290 221 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 167036510 Nonpathogen - hypothetical protein Teth39_0079 1 None None None 167037096 Common - hypothetical protein Teth39_0675 85 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 167037165 Common - permease Teth39_0748 87 COG0701 COG0701, Predicted permeases General function prediction only 167037231 Common - protein of unknown function DUF881 Teth39_0816 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 167037957 Common - capsular exopolysaccharide family Teth39_1554 187 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 167037433 Common - hypothetical protein Teth39_1020 7 None None None 167036973 Common - ATP-dependent metalloprotease FtsH Teth39_0551 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 167037678 Common - Ribonuclease H Teth39_1266 231 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 167038484 Common - CMP/dCMP deaminase, zinc-binding Teth39_2103 97 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 167037427 Common - Holliday junction DNA helicase RuvB Teth39_1014 233 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 167037893 Common - hypothetical protein Teth39_1486 12 None None None 167037346 Common - hypothetical protein Teth39_0933 10 None None None 167038584 Common - Group II intron, maturase-specific domain protein Teth39_2205 40 None None None 167037817 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Teth39_1408 18 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 167036443 Common - NADH:flavin oxidoreductase/NADH oxidase Teth39_0012 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 167036586 Common - heat shock protein Hsp20 Teth39_0155 173 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 167037372 Common - NADH:flavin oxidoreductase/NADH oxidase Teth39_0959 244 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 167036504 Common - transcriptional regulator, XRE family Teth39_0073 13 COG2944 COG2944, Predicted transcriptional regulator Transcription 167037507 Common - hypothetical protein Teth39_1094 15 None None None 167036833 Common - cobalt transport protein Teth39_0406 79 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 167037975 Common - V-type H(+)-translocating pyrophosphatase Teth39_1572 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 167036911 Common - alanine racemase Teth39_0487 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 167037670 Common - flagellar hook-basal body complex subunit FliE Teth39_1258 82 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 167037307 Common - tryptophan synthase, beta subunit Teth39_0893 228 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 167037713 Common - putative methyltransferase Teth39_1301 215 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 167036436 Common - hypothetical protein Teth39_0005 10 None None None 167037463 Nonpathogen - hypothetical protein Teth39_1050 1 None None None 167037422 Common - protein of unknown function DUF28 Teth39_1009 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 167036438 Common - CobB/CobQ domain protein glutamine amidotransferase Teth39_0007 82 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 167038534 Common - DNA-3-methyladenine glycosylase I Teth39_2153 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 167037808 Nonpathogen - hypothetical protein Teth39_1399 1 None None None 167037409 Common - Orn/Lys/Arg decarboxylase, major region Teth39_0996 95 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 167038041 Common - magnesium transporter Teth39_1641 186 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 167037217 Common - peptidase M16 domain protein Teth39_0802 92 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 167036592 Common - UDP-N-acetylglucosamine pyrophosphorylase Teth39_0161 236 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 167038472 Common - hypothetical protein Teth39_2091 16 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 167037160 Common - purine nucleoside phosphorylase Teth39_0743 102 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 167038185 Common - Methionine adenosyltransferase Teth39_1790 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 167038440 Common - extracellular solute-binding protein, family 1 Teth39_2058 29 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 167038539 Common - protein of unknown function DUF395, YeeE/YedE Teth39_2158 72 None None None 167037457 Common - cobalamin B12-binding domain protein Teth39_1044 37 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 167037075 Common - anaerobic ribonucleoside-triphosphate reductase Teth39_0653 130 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 167037002 Common - protein of unknown function DUF624 Teth39_0580 6 COG5578 COG5578, Predicted integral membrane protein Function unknown 167037253 Common - protein of unknown function DUF512 Teth39_0838 32 COG1625 COG1625, Fe-S oxidoreductase, related to NifB/MoaA family Energy production and conversion 167037778 Common - 7TM receptor with intracellular metal dependent phosphohydrolase Teth39_1368 59 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 167037621 Common - translation initiation factor IF-2 Teth39_1209 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 167037750 Common - protein of unknown function Met10 Teth39_1338 142 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 167036955 Common - polysaccharide deacetylase Teth39_0532 130 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 167038577 Common - CrcB protein Teth39_2197 18 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 167036535 Common - peptidase S1 and S6, chymotrypsin/Hap Teth39_0104 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 167037632 Common - undecaprenyl diphosphate synthase Teth39_1220 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 167038435 Common - ROK family protein Teth39_2053 150 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 167037070 Common - transport system permease protein Teth39_0648 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 167037737 Common - protein of unknown function DUF370 Teth39_1325 33 COG2052 COG2052, Uncharacterized protein conserved in bacteria Function unknown 167038505 Common - electron transport complex, RnfABCDGE type, C subunit Teth39_2124 116 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 167036555 Common - CRISPR-associated protein Cas5, Hmari subtype Teth39_0124 18 COG1688 COG1688, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 167037379 Common - Appr-1-p processing domain protein Teth39_0966 115 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 167037797 Nonpathogen - hypothetical protein Teth39_1387 1 None None None 167037315 Common - transglutaminase domain protein Teth39_0901 9 COG5279 CYK3, Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain Cell division and chromosome partitioning 167036451 Common - acetolactate synthase, large subunit, biosynthetic type Teth39_0020 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 167038647 Common - replicative DNA helicase Teth39_2268 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 167037184 Common - translation initiation factor IF-3 Teth39_0767 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 167038595 Common - transcriptional regulator, XRE family Teth39_2216 13 COG2944 COG2944, Predicted transcriptional regulator Transcription 167036903 Common - protein of unknown function DUF503 Teth39_0479 28 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 167036986 Common - protein of unknown function DUF214 Teth39_0564 113 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 167036826 Common - ribosomal protein S13 Teth39_0399 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 167037770 Common - transcriptional regulator with CBS sensor domain, DeoR family Teth39_1360 24 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 167038279 Common - glutamate-1-semialdehyde-2,1-aminomutase Teth39_1888 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 167037009 Common - transposase, putative Teth39_0587 9 None None None 167037885 Common - glycoside hydrolase, family 18 Teth39_1477 33 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 167037558 Common - Conserved carboxylase region Teth39_1145 186 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 167036994 Common - cell cycle protein Teth39_0572 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 167036930 Common - ABC transporter related Teth39_0506 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 167038135 Common - ABC transporter related Teth39_1740 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 167038082 Common - binding-protein-dependent transport systems inner membrane component Teth39_1687 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 167036880 Common - transport-associated Teth39_0455 24 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 167037579 Common - cytidylate kinase Teth39_1167 211 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 167037061 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis protein Teth39_0639 33 COG1433 COG1433, Uncharacterized conserved protein Function unknown 167038236 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Teth39_1842 115 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 167037088 Common - protein of unknown function UPF0052 and CofD Teth39_0667 101 COG0391 COG0391, Uncharacterized conserved protein Function unknown 167037210 Common - hypothetical protein Teth39_0795 5 None None None 167037666 Common - flagellar protein export ATPase FliI Teth39_1254 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 167036733 Nonpathogen - hypothetical protein Teth39_0306 2 None None None 167036935 Common - DNA polymerase, beta domain protein region Teth39_0512 13 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 167037484 Common - peptidase A24A domain protein Teth39_1071 127 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 167038231 Common - urocanate hydratase Teth39_1837 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 167038293 Common - ABC transporter related Teth39_1902 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 167036643 Common - phosphoesterase, PA-phosphatase related Teth39_0213 134 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 167038257 Common - hypothetical protein Teth39_1865 19 COG4923 COG4923, Uncharacterized conserved protein Function unknown 167037730 Common - protein of unknown function DUF116 Teth39_1318 31 COG1852 COG1852, Uncharacterized conserved protein Function unknown 167038141 Common - membrane protein-like protein Teth39_1746 22 COG3601 COG3601, Predicted membrane protein Function unknown 167037015 Common - Auxin Efflux Carrier Teth39_0593 141 COG0679 COG0679, Predicted permeases General function prediction only 167037601 Common - hypothetical protein Teth39_1189 8 None None None 167038198 Common - phosphoribosylaminoimidazole carboxylase, ATPase subunit Teth39_1803 194 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 167036750 Common - sugar fermentation stimulation protein Teth39_0323 109 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 167038556 Common - D-alanine--D-alanine ligase Teth39_2176 184 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 167038406 Common - cobalt ABC transporter, inner membrane subunit CbiQ Teth39_2022 68 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 167036840 Common - protein of unknown function DUF990 Teth39_0413 23 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 167037083 Common - Patatin Teth39_0662 128 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 167037756 Common - dihydroorotase, multifunctional complex type Teth39_1344 213 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 167037628 Common - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase Teth39_1216 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 167037538 Common - Stage V sporulation AD family protein Teth39_1125 15 None None None 167036454 Common - GTP cyclohydrolase II Teth39_0023 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 167038606 Nonpathogen - hypothetical protein Teth39_2227 4 None None None 167038268 Common - protein of unknown function DUF1648 Teth39_1876 21 COG5658 COG5658, Predicted integral membrane protein Function unknown 167038637 Common - H+-transporting two-sector ATPase, alpha/beta subunit, central region Teth39_2258 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 167037197 Common - Allergen V5/Tpx-1 family protein Teth39_0782 55 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 167036666 Common - Heptaprenyl diphosphate synthase component I Teth39_0237 23 COG4769 COG4769, Predicted membrane protein Function unknown 167037728 Common - sun protein Teth39_1316 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 167037034 Common - Alpha-mannosidase Teth39_0612 53 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 167037929 Common - small acid-soluble spore protein, alpha/beta type Teth39_1524 11 None None None 167037588 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Teth39_1176 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 167038335 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Teth39_1946 25 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 167038339 Common - hypothetical protein Teth39_1950 13 COG5464 COG5464, Uncharacterized conserved protein Function unknown 167037226 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Teth39_0811 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 167037769 Common - protein of unknown function DUF299 Teth39_1359 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 167036479 Common - hypothetical protein Teth39_0048 3 None None None 167036895 Common - phosphoglucosamine mutase Teth39_0471 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 167036659 Common - Argininosuccinate synthase Teth39_0229 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 167037927 Common - transcriptional regulator, LacI family Teth39_1522 130 COG1609 PurR, Transcriptional regulators Transcription 167037024 Common - galactose-1-phosphate uridylyltransferase Teth39_0602 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 167036680 Nonpathogen - hypothetical protein Teth39_0253 1 None None None 167038302 Common - cysteine desulfurase, SufS subfamily Teth39_1911 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 167038600 Nonpathogen - hypothetical protein Teth39_2221 1 None None None 167037542 Common - chromosome segregation and condensation protein ScpA Teth39_1129 144 COG1354 COG1354, Uncharacterized conserved protein Function unknown 167036472 Common - metal dependent phosphohydrolase Teth39_0041 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 167036715 Common - L-threonine 3-dehydrogenase Teth39_0288 210 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 167036650 Common - iron-containing alcohol dehydrogenase Teth39_0220 171 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 167038179 Common - flagellar hook-associated protein FlgK Teth39_1784 125 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 167037964 Nonpathogen - hypothetical protein Teth39_1561 1 None None None 167037113 Common - nitroreductase Teth39_0693 176 COG0778 NfnB, Nitroreductase Energy production and conversion 167037567 Common - Glu/Leu/Phe/Val dehydrogenase, C terminal Teth39_1154 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 167037626 Common - DNA polymerase III, alpha subunit Teth39_1214 219 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 167037091 Common - binding-protein-dependent transport systems inner membrane component Teth39_0670 166 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 167038012 Common - 4-oxalocrotonate tautomerase Teth39_1610 10 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 167037940 Common - two component transcriptional regulator, winged helix family Teth39_1535 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 167037732 Common - peptide deformylase Teth39_1320 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 167037194 Common - hypothetical protein Teth39_0777 14 None None None 167037400 Nonpathogen - hypothetical protein Teth39_0987 7 COG1645 COG1645, Uncharacterized Zn-finger containing protein General function prediction only 167038259 Nonpathogen - hypothetical protein Teth39_1867 2 None None None 167038158 Common - ABC transporter related Teth39_1763 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 167036464 Common - transcriptional regulator, XRE family Teth39_0033 30 COG1476 COG1476, Predicted transcriptional regulators Transcription 167036842 Common - Radical SAM domain protein Teth39_0415 30 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 167037337 Common - DEAD/DEAH box helicase domain protein Teth39_0924 196 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 167037982 Nonpathogen - hypothetical protein Teth39_1580 1 COG4088 COG4088, Predicted nucleotide kinase Nucleotide transport and metabolism 167038036 Nonpathogen - hypothetical protein Teth39_1636 2 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 167038095 Nonpathogen - hypothetical protein Teth39_1700 1 None None None 167038306 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Teth39_1917 31 COG1150 HdrC, Heterodisulfide reductase, subunit C Energy production and conversion 167038587 Nonpathogen - hypothetical protein Teth39_2208 5 None None None 167036673 Common - major facilitator superfamily MFS_1 Teth39_0246 156 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 167038507 Nonpathogen - hypothetical protein Teth39_2126 7 None None None 167037903 Common - glutamine synthetase, type I Teth39_1496 229 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 167036549 Common - SufBD protein Teth39_0118 178 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 167038381 Common - L-lactate dehydrogenase Teth39_1997 164 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 167038514 Common - hypothetical protein Teth39_2133 3 None None None 167038553 Common - alpha amylase, catalytic region Teth39_2173 172 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 167037972 Nonpathogen - DNA polymerase, beta domain protein region Teth39_1569 6 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 167037100 Common - Phosphotransferase system, phosphocarrier protein HPr Teth39_0679 162 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 167038498 Nonpathogen - hypothetical protein Teth39_2117 1 None None None 167036815 Common - ribosomal protein S8 Teth39_0388 249 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 167037150 Common - Phosphoglycerate kinase Teth39_0732 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 167037616 Common - ribosomal protein S15 Teth39_1204 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 167037321 Common - sodium ion-translocating decarboxylase, beta subunit Teth39_0907 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 167036706 Common - cysteine synthase A Teth39_0279 224 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 167036590 Common - purine operon repressor, PurR Teth39_0159 98 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 167038413 Nonpathogen - hypothetical protein Teth39_2029 2 None None None 167036689 Common - binding-protein-dependent transport systems inner membrane component Teth39_0262 158 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 167038067 Nonpathogen - addiction module toxin, RelE/StbE family Teth39_1670 4 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 167037997 Common - hypothetical protein Teth39_1595 34 COG0716 FldA, Flavodoxins Energy production and conversion 167036807 Common - ribosomal protein S3 Teth39_0380 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 167037883 Common - phage shock protein C, PspC Teth39_1475 53 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 167037247 Nonpathogen - protein of unknown function DUF1614 Teth39_0832 12 COG4089 COG4089, Predicted membrane protein Function unknown 167037848 Common - hypothetical protein Teth39_1440 43 COG5011 COG5011, Uncharacterized protein conserved in bacteria Function unknown 167037385 Common - beta-lactamase domain protein Teth39_0972 83 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 167038298 Common - putative RNA methylase Teth39_1907 135 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 167036541 Nonpathogen - hypothetical protein Teth39_0110 1 None None None 167038104 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Teth39_1709 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 167037274 Common - molybdenum cofactor synthesis domain Teth39_0860 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 167038276 Common - cobalt transport protein Teth39_1885 42 COG1930 CbiN, ABC-type cobalt transport system, periplasmic component Inorganic ion transport and metabolism 167036740 Nonpathogen - hypothetical protein Teth39_0313 1 None None None 167037935 Common - valyl-tRNA synthetase Teth39_1530 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167037266 Common - thiamineS protein Teth39_0852 10 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 167037578 Common - Chorismate mutase-like protein Teth39_1166 22 COG4401 AroH, Chorismate mutase Amino acid transport and metabolism 167036655 Common - acetylglutamate kinase Teth39_0225 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 167037043 Common - putative transaldolase Teth39_0621 179 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 167038320 Common - binding-protein-dependent transport systems inner membrane component Teth39_1931 203 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 167038669 Common - tRNA modification GTPase TrmE Teth39_2290 237 COG0486 ThdF, Predicted GTPase General function prediction only 167038464 Common - hypothetical protein Teth39_2083 19 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 167037795 Common - Integrase, catalytic region Teth39_1385 64 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 167036649 Common - Integrase, catalytic region Teth39_0219 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 167038209 Nonpathogen - hypothetical protein Teth39_1815 10 None None None 167038136 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Teth39_1741 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 167037789 Common - metal dependent phosphohydrolase Teth39_1379 118 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 167037865 Common - NADH dehydrogenase (quinone) Teth39_1457 201 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 167038479 Common - pyruvate phosphate dikinase, PEP/pyruvate-binding Teth39_2098 50 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 167037326 Common - large conductance mechanosensitive channel protein Teth39_0913 140 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 167038309 Nonpathogen - hypothetical protein Teth39_1920 1 None None None 167037221 Nonpathogen - cell division protein FtsL Teth39_0806 4 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 167037431 Common - preprotein translocase, YajC subunit Teth39_1018 165 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 167038516 Common - 3D domain protein Teth39_2135 27 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 167038569 Common - pseudouridine synthase Teth39_2189 209 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 167038425 Common - ribokinase Teth39_2042 215 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 167038662 Common - cysteine desulfurase family protein Teth39_2283 246 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 167037390 Common - cyclase family protein Teth39_0977 75 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 167037916 Common - transposase IS116/IS110/IS902 family protein Teth39_1510 58 None None None 167036560 Common - transposase IS116/IS110/IS902 family protein Teth39_0129 99 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 167036965 Common - dihydroxyacetone kinase, DhaK subunit Teth39_0542 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 167037721 Nonpathogen - hypothetical protein Teth39_1309 1 None None None 167036633 Common - hypothetical protein Teth39_0203 8 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 167037176 Common - Thioredoxin domain Teth39_0759 17 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 167038261 Common - AAA ATPase Teth39_1869 69 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 167037133 Common - phosphoribulokinase/uridine kinase Teth39_0715 192 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 167036856 Common - carbon starvation protein CstA Teth39_0431 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 167038447 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Teth39_2065 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 167037646 Common - type IV pilus assembly PilZ Teth39_1234 18 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 167038162 Common - hypothetical protein Teth39_1767 14 None None None 167038490 Common - peptide chain release factor 1 Teth39_2109 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 167037265 Common - Radical SAM domain protein Teth39_0851 65 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 167037873 Common - hypothetical protein Teth39_1465 8 None None None 167038615 Common - hypothetical protein Teth39_2236 7 None None None 167037351 Nonpathogen - hypothetical protein Teth39_0938 1 None None None 167037098 Nonpathogen - hypothetical protein Teth39_0677 1 None None None 167037561 Common - stationary-phase survival protein SurE Teth39_1148 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 167038560 Common - glycosidase, PH1107-related Teth39_2180 37 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 167037235 Common - peptidase U4, sporulation factor SpoIIGA Teth39_0820 15 None None None 167038071 Common - 2-keto-3-deoxygluconate permease Teth39_1676 27 COG2855 COG2855, Predicted membrane protein Function unknown 167037155 Common - putative deoxyguanosinetriphosphate triphosphohydrolase Teth39_0737 163 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 167036679 Common - YabP family protein Teth39_0252 15 None None None 167036828 Common - RNA-binding S4 domain protein Teth39_0401 248 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 167037932 Nonpathogen - hypothetical protein Teth39_1527 1 None None None 167038167 Common - flagellar protein FlaG protein Teth39_1772 13 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 167037446 Common - efflux transporter, RND family, MFP subunit Teth39_1033 153 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 167037412 Common - ATPase of the ABC class-like protein Teth39_0999 26 COG3044 COG3044, Predicted ATPase of the ABC class General function prediction only 167036482 Nonpathogen - hypothetical protein Teth39_0051 4 None None None 167037122 Common - RNA methyltransferase, TrmA family Teth39_0702 199 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 167037206 Common - Transketolase, central region Teth39_0791 209 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 167037073 Common - formylmethanofuran dehydrogenase, subunit E region Teth39_0651 39 COG2191 COG2191, Formylmethanofuran dehydrogenase subunit E Energy production and conversion 167037147 Common - RNA polymerase, sigma 54 subunit, RpoN Teth39_0729 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 167038195 Common - hypothetical protein Teth39_1800 7 None None None 167036861 Common - Na+/H+ antiporter MnhB subunit-related protein Teth39_0436 100 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 167038283 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Teth39_1892 108 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 167036882 Common - protein of unknown function DUF147 Teth39_0457 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 167038020 Nonpathogen - hypothetical protein Teth39_1620 1 None None None 167036996 Common - excinuclease ABC, C subunit Teth39_0574 225 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 167038427 Common - Integrase, catalytic region Teth39_2044 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 167038174 Common - flagellin domain protein Teth39_1779 123 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 167037772 Common - ubiquitin-associated- domain-containing protein Teth39_1362 8 None None None 167038147 Nonpathogen - copper amine oxidase domain protein Teth39_1752 9 None None None 167037174 Common - putative cold-shock DNA-binding domain protein Teth39_0757 181 COG1278 CspC, Cold shock proteins Transcription 167037649 Common - flagellar biosynthesis protein FlhA Teth39_1237 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 167037871 Common - Fe-S cluster domain protein Teth39_1463 59 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 167036628 Common - major facilitator superfamily MFS_1 Teth39_0197 20 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 167037814 Common - DNA polymerase III, delta subunit Teth39_1405 57 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 167037712 Common - pantetheine-phosphate adenylyltransferase Teth39_1300 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 167036749 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Teth39_0322 141 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 167036821 Common - Nucleoside-triphosphate--adenylate kinase Teth39_0394 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 167037996 Common - hypothetical protein Teth39_1594 29 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 167038592 Nonpathogen - peptidase A24A, prepilin type IV Teth39_2213 1 None None None 167038400 Common - MATE efflux family protein Teth39_2016 192 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 167037700 Common - malonyl CoA-acyl carrier protein transacylase Teth39_1288 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 167038080 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Teth39_1685 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 167036588 Common - transcriptional regulator, LacI family Teth39_0157 130 COG1609 PurR, Transcriptional regulators Transcription 167038217 Common - PTS system, N-acetylglucosamine-specific IIBC subunit Teth39_1823 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 167037039 Common - transcriptional regulator, AraC family Teth39_0617 114 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 167037068 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Teth39_0646 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 167038636 Common - V-type ATPase, D subunit Teth39_2257 45 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 167036843 Common - Radical SAM domain protein Teth39_0416 40 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 167037638 Nonpathogen - hypothetical protein Teth39_1226 1 None None None 167037053 Common - AAA ATPase Teth39_0631 70 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 167037888 Nonpathogen - hypothetical protein Teth39_1480 2 None None None 167037232 Common - protein of unknown function DUF1290 Teth39_0817 25 COG3856 Sbp, Uncharacterized conserved protein (small basic protein) Function unknown 167038278 Nonpathogen - hypothetical protein Teth39_1887 1 None None None 167038344 Common - AzlC family protein Teth39_1955 112 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 167038502 Common - electron transport complex, RnfABCDGE type, E subunit Teth39_2121 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 167037208 Common - catalytic domain of components of various dehydrogenase complexes Teth39_0793 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 167037163 Common - hypothetical protein Teth39_0746 4 None None None 167037377 Common - Glycerophosphodiester phosphodiesterase Teth39_0964 186 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 167038437 Common - glycoside hydrolase, family 3 domain protein Teth39_2055 158 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 167037227 Common - stage V sporulation protein E Teth39_0812 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 167038333 Common - glycoside hydrolase, family 4 Teth39_1944 54 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 167037017 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Teth39_0595 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 167037420 Common - hypothetical protein Teth39_1007 4 COG0730 COG0730, Predicted permeases General function prediction only 167036983 Common - ABC transporter related Teth39_0561 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 167037551 Common - Serine-type D-Ala-D-Ala carboxypeptidase Teth39_1138 157 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 167037664 Common - hypothetical protein Teth39_1252 30 COG3334 COG3334, Uncharacterized conserved protein Function unknown 167038142 Common - carbamate kinase Teth39_1747 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 167037301 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_0887 100 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167037622 Common - ribosomal protein L7Ae/L30e/S12e/Gadd45 Teth39_1210 11 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 167037393 Common - L-serine dehydratase, iron-sulfur-dependent, alpha subunit Teth39_0980 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 167038541 Common - hypothetical protein Teth39_2160 7 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 167037576 Common - HI0933 family protein Teth39_1164 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 167037056 Common - protein of unknown function DUF43 Teth39_0634 15 COG1568 COG1568, Predicted methyltransferases General function prediction only 167037136 Common - Radical SAM domain protein Teth39_0718 129 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 167037866 Common - hypothetical protein Teth39_1458 22 COG3411 COG3411, Ferredoxin Energy production and conversion 167036580 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_0149 100 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167037308 Common - tryptophan synthase, alpha subunit Teth39_0894 219 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 167037072 Common - protein of unknown function UPF0066 Teth39_0650 98 COG1720 COG1720, Uncharacterized conserved protein Function unknown 167037131 Common - pseudouridine synthase, RluA family Teth39_0713 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 167036730 Common - Formate--tetrahydrofolate ligase Teth39_0303 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 167038467 Nonpathogen - hypothetical protein Teth39_2086 1 None None None 167037320 Nonpathogen - sodium pump decarboxylase, gamma subunit Teth39_0906 1 COG3630 OadG, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, gamma subunit Energy production and conversion 167036575 Common - Alanine--glyoxylate transaminase Teth39_0144 180 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 167037806 Common - GTP-binding protein LepA Teth39_1397 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 167037329 Nonpathogen - hypothetical protein Teth39_0916 5 None None None 167036933 Common - hypothetical protein Teth39_0509 10 None None None 167038575 Common - metal dependent phosphohydrolase Teth39_2195 123 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 167037319 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Teth39_0905 107 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 167036562 Common - transposase IS116/IS110/IS902 family protein Teth39_0131 99 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037719 Common - protein of unknown function DUF322 Teth39_1307 30 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 167036846 Common - transposase, mutator type Teth39_0421 87 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037672 Common - flagellar basal-body rod protein FlgB Teth39_1260 42 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 167038244 Nonpathogen - hypothetical protein Teth39_1851 7 None None None 167036638 Nonpathogen - hypothetical protein Teth39_0208 1 None None None 167036999 Common - PHP C-terminal domain protein Teth39_0577 93 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 167036606 Common - Peptidoglycan-binding LysM Teth39_0175 8 None None None 167036759 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Teth39_0332 142 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 167036786 Common - ribosomal protein L33 Teth39_0359 93 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 167038451 Common - phosphotransferase system PTS, sorbose-specific IIC subunit Teth39_2069 33 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 167037765 Common - SsrA-binding protein Teth39_1355 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 167036707 Common - Cysteine desulfurase Teth39_0280 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 167037146 Common - acylphosphatase Teth39_0728 31 COG1254 AcyP, Acylphosphatases Energy production and conversion 167037344 Common - ATPase associated with various cellular activities, AAA_5 Teth39_0931 51 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 167037618 Common - tRNA pseudouridine synthase B Teth39_1206 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 167036776 Common - prolyl-tRNA synthetase Teth39_0349 248 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167038119 Nonpathogen - hypothetical protein Teth39_1724 1 None None None 167036640 Common - ABC transporter related Teth39_0210 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 167038256 Common - alpha/beta hydrolase fold Teth39_1864 86 COG2267 PldB, Lysophospholipase Lipid metabolism 167038275 Common - cobalt ABC transporter, inner membrane subunit CbiQ Teth39_1884 68 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 167038446 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Teth39_2064 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 167038415 Common - transposase, mutator type Teth39_2032 89 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037478 Common - HAD superfamily (subfamily IIIA) phosphatase, TIGR01668 Teth39_1065 46 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 167036481 Nonpathogen - hypothetical protein Teth39_0050 1 None None None 167038187 Nonpathogen - hypothetical protein Teth39_1792 1 None None None 167037841 Common - ribosomal protein L27 Teth39_1433 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 167037692 Common - chromosome segregation protein SMC Teth39_1280 205 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 167038035 Common - transposase, IS605 OrfB family Teth39_1635 54 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037048 Common - binding-protein-dependent transport systems inner membrane component Teth39_0626 147 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 167037187 Common - tRNA/rRNA methyltransferase (SpoU) Teth39_0770 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 167037691 Common - signal recognition particle-docking protein FtsY Teth39_1279 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 167037295 Common - cobalt transport protein Teth39_0881 51 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 167036599 Nonpathogen - hypothetical protein Teth39_0168 5 None None None 167036836 Common - ribosomal protein S9 Teth39_0409 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 167036960 Common - FAD dependent oxidoreductase Teth39_0537 173 COG0579 COG0579, Predicted dehydrogenase General function prediction only 167037985 Nonpathogen - hypothetical protein Teth39_1583 1 None None None 167037356 Common - transcriptional regulator, XRE family Teth39_0943 4 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 167036816 Common - ribosomal protein L6 Teth39_0389 242 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 167037705 Common - ribosomal protein L32 Teth39_1293 37 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 167036886 Common - Glu/Leu/Phe/Val dehydrogenase, dimerisation region Teth39_0461 129 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 167038227 Common - basic membrane lipoprotein Teth39_1833 108 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 167038474 Common - flagellar basal body rod protein Teth39_2093 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 167036617 Common - hypothetical protein Teth39_0186 12 None None None 167037859 Common - rod shape-determining protein MreC Teth39_1451 156 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 167038377 Common - protein of unknown function DUF296 Teth39_1993 36 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 167036906 Common - hypothetical protein Teth39_0482 4 None None None 167037593 Common - Aluminium resistance family protein Teth39_1181 33 COG4100 COG4100, Cystathionine beta-lyase family protein involved in aluminum resistance Inorganic ion transport and metabolism 167038610 Common - hypothetical protein Teth39_2231 5 COG3941 COG3941, Mu-like prophage protein General function prediction only 167037782 Common - Asparaginase/glutaminase Teth39_1372 139 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 167036725 Common - stage II sporulation protein E, protein serine/threonine phosphatase Teth39_0298 57 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 167038640 Common - H(+)-transporting two-sector ATPase Teth39_2261 29 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 167037851 Common - peptidase M23B Teth39_1443 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 167037681 Common - protein of unknown function DUF161 Teth39_1269 81 COG1284 COG1284, Uncharacterized conserved protein Function unknown 167036745 Common - lysyl-tRNA synthetase Teth39_0318 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 167037010 Common - transcriptional regulator, LacI family Teth39_0588 131 COG1609 PurR, Transcriptional regulators Transcription 167036976 Nonpathogen - hypothetical protein Teth39_0554 3 None None None 167038659 Common - cyanophycinase Teth39_2280 34 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 167036494 Nonpathogen - SAF domain Teth39_0063 1 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 167038350 Common - hypothetical protein Teth39_1963 34 COG3580 COG3580, Uncharacterized protein conserved in bacteria Function unknown 167036621 Common - DNA mismatch repair protein MutS domain protein Teth39_0190 199 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 167038357 Common - PfkB domain protein Teth39_1972 219 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 167038652 Common - ribosomal protein S18 Teth39_2273 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 167038351 Common - transcriptional regulator, TetR family Teth39_1964 31 COG1309 AcrR, Transcriptional regulator Transcription 167037611 Common - PRC-barrel domain protein Teth39_1199 14 COG1873 COG1873, Uncharacterized conserved protein Function unknown 167037481 Common - twitching motility protein Teth39_1068 170 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 167038458 Common - Altronate dehydratase Teth39_2076 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 167036699 Nonpathogen - hypothetical protein Teth39_0272 1 COG3462 COG3462, Predicted membrane protein Function unknown 167036876 Common - ATPase associated with various cellular activities, AAA_3 Teth39_0451 187 COG0714 COG0714, MoxR-like ATPases General function prediction only 167037093 Common - alpha amylase, catalytic region Teth39_0672 155 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 167038129 Common - signal transduction histidine kinase regulating citrate/malate metabolism Teth39_1734 65 COG3290 CitA, Signal transduction histidine kinase regulating citrate/malate metabolism Signal transduction mechanisms 167038642 Common - H+-transporting two-sector ATPase, C subunit Teth39_2263 17 None None None 167036596 Common - integral membrane sensor signal transduction histidine kinase Teth39_0165 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 167037128 Nonpathogen - hypothetical protein Teth39_0709 3 None None None 167038266 Common - Cellulase Teth39_1874 90 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 167036701 Common - two component transcriptional regulator, winged helix family Teth39_0274 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 167037450 Common - UBA/THIF-type NAD/FAD binding protein Teth39_1037 217 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 167036522 Common - DNA binding domain, excisionase family Teth39_0091 10 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 167037205 Common - Pyruvate dehydrogenase (acetyl-transferring) Teth39_0790 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 167037609 Common - peptidase S14, ClpP Teth39_1197 31 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 167036761 Common - PTS system, fructose-specific, IIB subunnit Teth39_0334 68 COG1445 FrwB, Phosphotransferase system fructose-specific component IIB Carbohydrate transport and metabolism 167037550 Nonpathogen - hypothetical protein Teth39_1137 1 None None None 167038551 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit Teth39_2171 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 167038617 Nonpathogen - hypothetical protein Teth39_2238 1 None None None 167037496 Common - gamma-glutamyl phosphate reductase Teth39_1083 191 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 167038077 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Teth39_1682 235 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 167037898 Common - peptidase M23B Teth39_1491 193 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 167037157 Common - RNA polymerase, sigma 70 subunit, RpoD family Teth39_0739 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 167037832 Nonpathogen - cobalamin B12-binding domain protein Teth39_1424 7 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 167038139 Common - peptidase M22, glycoprotease Teth39_1744 198 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 167037152 Common - phosphoglycerate mutase, 2,3-bisphosphoglycerate-independent Teth39_0734 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 167036869 Nonpathogen - Coat F domain protein Teth39_0444 10 COG5577 COG5577, Spore coat protein Cell envelope biogenesis, outer membrane 167037642 Common - CheC, inhibitor of MCP methylation Teth39_1230 45 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 167038101 Common - glutamate racemase Teth39_1706 188 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 167038160 Common - extracellular solute-binding protein, family 3 Teth39_1765 194 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 167038065 Common - protein of unknown function UPF0236 Teth39_1667 8 None None None 167036708 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Teth39_0281 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 167037109 Common - 2-isopropylmalate synthase/homocitrate synthase family protein Teth39_0689 217 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 167036862 Common - NADH-ubiquinone oxidoreductase, chain 4L Teth39_0437 63 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 167037383 Common - hypothetical protein Teth39_0970 14 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 167037986 Nonpathogen - hypothetical protein Teth39_1584 3 None None None 167037118 Common - YbaK/prolyl-tRNA synthetase associated region Teth39_0698 77 COG2606 EbsC, Uncharacterized conserved protein Function unknown 167038002 Nonpathogen - hypothetical protein Teth39_1600 1 None None None 167037846 Common - GTP cyclohydrolase I Teth39_1438 102 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 167038635 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Teth39_2256 67 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037144 Common - ferric uptake regulator, Fur family Teth39_0726 210 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 167037289 Common - amidohydrolase Teth39_0875 177 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 167036597 Common - 2-alkenal reductase Teth39_0166 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 167037493 Common - Shikimate kinase Teth39_1080 195 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 167037434 Common - Radical SAM domain protein Teth39_1021 95 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 167038319 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Teth39_1930 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 167038460 Common - Phosphoglycerate dehydrogenase Teth39_2078 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 167036771 Common - hypothetical protein Teth39_0344 9 None None None 167037839 Common - small GTP-binding protein Teth39_1431 249 COG0536 Obg, Predicted GTPase General function prediction only 167036768 Common - ATP:guanido phosphotransferase Teth39_0341 25 COG3869 COG3869, Arginine kinase Amino acid transport and metabolism 167036657 Common - carbamoyl-phosphate synthase, small subunit Teth39_0227 235 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 167037255 Common - protein of unknown function DUF205 Teth39_0840 170 COG0344 COG0344, Predicted membrane protein Function unknown 167036502 Common - hypothetical protein Teth39_0071 19 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 167037563 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Teth39_1150 117 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 167036529 Common - peptidase M1, membrane alanine aminopeptidase Teth39_0098 156 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 167036747 Common - dihydropteroate synthase Teth39_0320 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 167037260 Common - putative CoA-substrate-specific enzyme activase Teth39_0845 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 167037528 Common - NUDIX hydrolase Teth39_1115 183 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 167037767 Common - metal dependent phosphohydrolase Teth39_1357 40 COG2316 COG2316, Predicted hydrolase (HD superfamily) General function prediction only 167036682 Common - Inorganic diphosphatase Teth39_0255 57 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 167037271 Common - ABC transporter related Teth39_0857 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 167037853 Common - rod shape-determining protein RodA Teth39_1445 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 167038567 Common - extracellular solute-binding protein, family 5 Teth39_2187 142 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 167037529 Common - hypothetical protein Teth39_1116 35 COG1379 COG1379, Uncharacterized conserved protein Function unknown 167038078 Common - ribonuclease PH Teth39_1683 217 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 167037476 Common - Peptidoglycan glycosyltransferase Teth39_1063 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 167037961 Common - NusG antitermination factor Teth39_1558 180 COG0250 NusG, Transcription antiterminator Transcription 167036757 Common - diguanylate cyclase with GAF sensor Teth39_0330 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 167037276 Common - molybdenum cofactor biosynthesis protein C Teth39_0862 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 167038249 Nonpathogen - hypothetical protein Teth39_1856 1 None None None 167038522 Common - transcriptional regulator, AbrB family Teth39_2141 16 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 167038664 Common - Cobyrinic acid a,c-diamide synthase Teth39_2285 230 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 167038294 Common - transport system permease protein Teth39_1903 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 167037245 Common - phosphate ABC transporter, ATPase subunit Teth39_0830 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 167037537 Common - SpoVA protein Teth39_1124 15 None None None 167036858 Common - cation antiporter Teth39_0433 6 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 167037429 Common - S-adenosylmethionine--tRNA-ribosyltransferase-isomerase Teth39_1016 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 167038102 Nonpathogen - hypothetical protein Teth39_1707 1 None None None 167037976 Common - putative small multi-drug export Teth39_1573 21 COG2426 COG2426, Predicted membrane protein Function unknown 167036465 Common - excision promoter, Xis Teth39_0034 4 COG3311 AlpA, Predicted transcriptional regulator Transcription 167038316 Common - Beta-glucosidase Teth39_1927 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 167037106 Common - thioesterase superfamily protein Teth39_0685 127 COG0824 FcbC, Predicted thioesterase General function prediction only 167037138 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Teth39_0720 41 COG1141 Fer, Ferredoxin Energy production and conversion 167037925 Common - extracellular solute-binding protein, family 1 Teth39_1520 129 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 167036917 Common - hypothetical protein Teth39_0493 14 COG4739 COG4739, Uncharacterized protein containing a ferredoxin domain Function unknown 167038097 Common - transcriptional antiterminator, BglG Teth39_1702 34 COG3711 BglG, Transcriptional antiterminator Transcription 167037826 Common - AAA ATPase Teth39_1418 70 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 167037548 Common - protein of unknown function DUF107 Teth39_1135 80 COG1030 NfeD, Membrane-bound serine protease (ClpP class) Posttranslational modification, protein turnover, chaperones 167037316 Common - methylmalonyl-CoA mutase, large subunit Teth39_0902 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 167038019 Common - ATP-cone domain protein Teth39_1617 5 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 167037182 Common - major facilitator superfamily MFS_1 Teth39_0765 18 None None None 167038225 Common - inner-membrane translocator Teth39_1831 121 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 167038487 Common - arsenate reductase Teth39_2106 140 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 167038312 Common - ferric uptake regulator, Fur family Teth39_1923 154 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 167037505 Common - hypothetical protein Teth39_1092 15 None None None 167036543 Common - DNA repair photolyase-like protein Teth39_0112 16 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 167037930 Common - hypothetical protein Teth39_1525 4 None None None 167037263 Common - hypothetical protein Teth39_0849 3 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 167038205 Common - glucose-inhibited division protein A Teth39_1811 34 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 167037598 Common - Stage V sporulation protein S Teth39_1186 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 167037794 Common - ABC transporter related Teth39_1384 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 167036818 Common - ribosomal protein S5 Teth39_0391 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 167036809 Common - ribosomal protein L29 Teth39_0382 201 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 167038518 Common - methionyl-tRNA synthetase Teth39_2137 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167038057 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Teth39_1658 246 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 167036459 Common - signal peptidase I Teth39_0028 208 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 167036452 Common - riboflavin biosynthesis protein RibD Teth39_0021 232 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 167037994 Common - transcriptional regulator, MerR family Teth39_1592 134 COG0789 SoxR, Predicted transcriptional regulators Transcription 167038626 Common - peptidase S9, prolyl oligopeptidase active site domain protein Teth39_2247 115 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 167037749 Common - PP-loop domain protein Teth39_1337 171 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 167038604 Common - ATPase involved in chromosome partitioning-like protein Teth39_2225 12 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 167038235 Common - Amino acid transporter-like protein Teth39_1841 33 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 167036851 Common - Integrase, catalytic region Teth39_0426 139 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037111 Common - dienelactone hydrolase Teth39_0691 114 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 167036488 Common - Integrase, catalytic region Teth39_0057 57 None None None 167037966 Common - DNA polymerase, beta domain protein region Teth39_1563 36 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 167038390 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Teth39_2006 214 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 167038418 Common - Integrase, catalytic region Teth39_2035 57 None None None 167037582 Common - RNA binding S1 domain protein Teth39_1170 223 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 167037651 Common - flagellar biosynthetic protein FliR Teth39_1239 124 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 167037191 Common - peptidase U32 Teth39_0774 140 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 167037280 Common - putative endoribonuclease L-PSP Teth39_0866 192 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 167036652 Common - protein serine/threonine phosphatase Teth39_0222 12 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 167037516 Common - deoxyxylulose-5-phosphate synthase Teth39_1103 228 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 167037904 Nonpathogen - hypothetical protein Teth39_1497 1 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 167036474 Common - nucleic acid-binding protein contains PIN domain-like protein Teth39_0043 18 COG2405 COG2405, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 167037036 Common - binding-protein-dependent transport systems inner membrane component Teth39_0614 148 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 167038124 Common - ferredoxin-dependent glutamate synthase Teth39_1729 28 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 167037530 Common - protein of unknown function DUF95, transmembrane Teth39_1117 16 COG1300 SpoIIM, Uncharacterized membrane protein Function unknown 167036668 Common - Integrase, catalytic region Teth39_0240 50 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 167038026 Common - dTDP-4-dehydrorhamnose reductase Teth39_1626 187 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 167036811 Common - ribosomal protein L14 Teth39_0384 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 167037081 Nonpathogen - hypothetical protein Teth39_0660 1 None None None 167038288 Common - hypothetical protein Teth39_1897 12 None None None 167036936 Common - protein of unknown function DUF820 Teth39_0513 30 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 167037322 Common - hypothetical protein Teth39_0909 4 None None None 167038010 Nonpathogen - hypothetical protein Teth39_1608 4 None None None 167038504 Common - electron transport complex, RnfABCDGE type, D subunit Teth39_2123 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 167036893 Common - Phosphate butyryltransferase Teth39_0468 134 COG0280 Pta, Phosphotransacetylase Energy production and conversion 167036471 Nonpathogen - hypothetical protein Teth39_0040 1 None None None 167037620 Common - ribosome-binding factor A Teth39_1208 191 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 167037229 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Teth39_0814 216 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 167036499 Nonpathogen - hypothetical protein Teth39_0068 1 None None None 167038589 Common - hypothetical protein Teth39_2210 16 None None None 167037362 Common - transposase, IS4 family protein Teth39_0949 8 None None None 167038417 Common - AAA ATPase Teth39_2034 70 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 167037467 Common - Holliday junction resolvase YqgF Teth39_1054 196 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 167037792 Common - Radical SAM domain protein Teth39_1382 100 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 167038546 Common - putative sigma54 specific transcriptional regulator Teth39_2166 170 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 167037624 Common - NusA antitermination factor Teth39_1212 224 COG0195 NusA, Transcription elongation factor Transcription 167037453 Common - dihydrodipicolinate reductase Teth39_1040 33 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 167036797 Common - ribosomal protein S7 Teth39_0370 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 167038247 Common - ABC transporter related Teth39_1854 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 167038573 Nonpathogen - sigmaK-factor processing regulatory BofA Teth39_2193 1 None None None 167036500 Nonpathogen - hypothetical protein Teth39_0069 1 None None None 167036551 Common - SUF system FeS assembly protein, NifU family Teth39_0120 167 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 167037282 Common - alanine racemase domain protein Teth39_0868 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 167037602 Common - regulatory protein RecX Teth39_1190 38 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 167038092 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Teth39_1697 30 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 167037129 Common - AAA ATPase, central domain protein Teth39_0710 244 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 167038144 Common - Arginine deiminase Teth39_1749 60 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 167037774 Common - deoxyribose-phosphate aldolase Teth39_1364 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 167038114 Common - GMP synthase, large subunit Teth39_1719 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 167038431 Nonpathogen - hypothetical protein Teth39_2049 5 None None None 167036823 Common - hypothetical protein Teth39_0396 7 COG2163 RPL14A, Ribosomal protein L14E/L6E/L27E Translation, ribosomal structure and biogenesis 167038671 Common - 60 kDa inner membrane insertion protein Teth39_2292 195 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 167037389 Common - glucose-6-phosphate 1-dehydrogenase Teth39_0976 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 167038374 Common - Glycine dehydrogenase (decarboxylating) Teth39_1990 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 167036573 Common - homoserine kinase Teth39_0142 122 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 167038052 Common - thiW protein Teth39_1653 16 COG4732 COG4732, Predicted membrane protein Function unknown 167037717 Common - ATP-dependent DNA helicase RecG Teth39_1305 231 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 167037134 Nonpathogen - hypothetical protein Teth39_0716 2 None None None 167037161 Common - mannose-6-phosphate isomerase, class I Teth39_0744 51 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 167036614 Common - hypothetical protein Teth39_0183 15 None None None 167037104 Common - 6-phosphofructokinase Teth39_0683 153 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 167038409 Nonpathogen - FeoA family protein Teth39_2025 14 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 167038273 Common - isocitrate dehydrogenase, NADP-dependent Teth39_1882 95 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 167037189 Common - phenylalanyl-tRNA synthetase, beta subunit Teth39_0772 248 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 167037436 Common - protein-export membrane protein SecD Teth39_1023 221 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 167036951 Common - Na+/Pi-cotransporter Teth39_0528 83 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 167036432 Common - chromosomal replication initiator protein DnaA Teth39_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 167038598 Nonpathogen - hypothetical protein Teth39_2219 1 None None None 167037546 Common - hypothetical protein Teth39_1133 21 COG3874 COG3874, Uncharacterized conserved protein Function unknown 167038591 Common - hypothetical protein Teth39_2212 23 COG5464 COG5464, Uncharacterized conserved protein Function unknown 167037404 Common - ROK family protein Teth39_0991 128 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 167038177 Common - hypothetical protein Teth39_1782 9 None None None 167037804 Common - heat-inducible transcription repressor HrcA Teth39_1395 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 167036519 Common - zinc finger, CHC2-family protein Teth39_0088 160 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 167036915 Common - Transketolase domain protein Teth39_0491 222 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 167037290 Common - class II aldolase/adducin family protein Teth39_0876 164 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 167038117 Common - chaperonin Cpn10 Teth39_1722 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 167038402 Common - tRNA/rRNA methyltransferase (SpoU) Teth39_2018 162 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 167037180 Common - hypothetical protein Teth39_0763 33 COG4399 COG4399, Uncharacterized protein conserved in bacteria Function unknown 167037332 Common - hypothetical protein Teth39_0919 9 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 167036712 Nonpathogen - phage holin, LL-H family Teth39_0285 2 None None None 167038132 Common - CoA-binding domain protein Teth39_1737 57 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 167038149 Common - peptide chain release factor 2 Teth39_1754 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 167037636 Common - translation elongation factor Ts Teth39_1224 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 167038420 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_2037 102 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167038439 Common - binding-protein-dependent transport systems inner membrane component Teth39_2057 150 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 167038181 Nonpathogen - hypothetical protein Teth39_1786 1 None None None 167037460 Nonpathogen - hypothetical protein Teth39_1047 3 COG3565 COG3565, Predicted dioxygenase of extradiol dioxygenase family General function prediction only 167037375 Common - Ste24 endopeptidase Teth39_0962 78 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 167037214 Common - hypothetical protein Teth39_0799 19 COG3877 COG3877, Uncharacterized protein conserved in bacteria Function unknown 167037443 Common - beta-lactamase domain protein Teth39_1030 224 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 167037171 Common - nitrogen-fixing NifU domain protein Teth39_0754 76 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 167037310 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Teth39_0896 230 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 167037877 Common - NLP/P60 protein Teth39_1469 144 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 167038172 Common - DNA adenine methylase Teth39_1777 95 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 167037753 Common - dihydroorotate dehydrogenase family protein Teth39_1341 166 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 167037079 Common - Integrase, catalytic region Teth39_0658 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 167036440 Common - hypothetical protein Teth39_0009 10 None None None 167036737 Common - spore germination protein Teth39_0310 15 None None None 167038127 Common - hypothetical protein Teth39_1732 11 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 167036981 Common - diaminopimelate decarboxylase Teth39_0559 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 167036888 Common - hypothetical protein Teth39_0463 15 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 167037703 Common - fatty acid/phospholipid synthesis protein PlsX Teth39_1291 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 167038060 Common - glutamine amidotransferase, class-II Teth39_1661 103 COG0067 GltB, Glutamate synthase domain 1 Amino acid transport and metabolism 167037949 Common - drug resistance transporter, EmrB/QacA subfamily Teth39_1546 208 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 167036970 Nonpathogen - hypothetical protein Teth39_0548 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 167036727 Common - hypoxanthine phosphoribosyltransferase Teth39_0300 150 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 167036511 Common - Radical SAM domain protein Teth39_0080 47 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 167037780 Common - putative stage IV sporulation YqfD Teth39_1370 15 None None None 167037058 Nonpathogen - hypothetical protein Teth39_0636 3 None None None 167038169 Common - asparagine synthase (glutamine-hydrolyzing) Teth39_1774 171 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 167036765 Nonpathogen - hypothetical protein Teth39_0338 1 None None None 167038004 Nonpathogen - CRISPR-associated RAMP protein, Cmr1 family Teth39_1602 12 COG1367 COG1367, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 167038456 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Teth39_2074 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 167037746 Common - lipoprotein, YaeC family Teth39_1334 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 167036753 Nonpathogen - protein of unknown function DUF896 Teth39_0326 1 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 167037003 Common - Extradiol ring-cleavage dioxygenase, class III enzyme, subunit B Teth39_0581 90 COG3885 COG3885, Uncharacterized conserved protein Function unknown 167037682 Common - Mg chelatase, subunit ChlI Teth39_1270 208 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 167038211 Common - hypothetical protein Teth39_1817 20 None None None 167037591 Common - Ribonuclease H Teth39_1179 178 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 167037513 Common - exodeoxyribonuclease VII, small subunit Teth39_1100 46 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 167036526 Common - beta-lactamase domain protein Teth39_0095 122 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 167037724 Common - ribosome small subunit-dependent GTPase A Teth39_1312 164 COG1162 COG1162, Predicted GTPases General function prediction only 167036969 Common - hypothetical protein Teth39_0547 6 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 167036874 Common - regulatory protein, MerR Teth39_0449 16 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 167038654 Common - ribosomal protein S6 Teth39_2275 210 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 167037028 Nonpathogen - hypothetical protein Teth39_0606 7 None None None 167037342 Common - PglZ domain Teth39_0929 17 None None None 167036979 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Teth39_0557 186 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 167036780 Common - cysteinyl-tRNA synthetase Teth39_0353 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167036925 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Teth39_0501 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 167036920 Common - osmosensitive K+ channel signal transduction histidine kinase, sensor domain Teth39_0496 90 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 167036908 Common - holo-acyl-carrier-protein synthase Teth39_0484 153 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 167036572 Common - threonine synthase Teth39_0141 172 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 167037735 Common - DNA-directed RNA polymerase, omega subunit Teth39_1323 16 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 167038254 Common - hypothetical protein Teth39_1862 12 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 167038375 Common - Glycine dehydrogenase (decarboxylating) Teth39_1991 174 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 167037688 Common - ribosomal protein S16 Teth39_1276 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 167036625 Common - ABC-2 type transporter Teth39_0194 18 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 167038281 Common - uroporphyrin-III C-methyltransferase Teth39_1890 206 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 167036636 Common - iron-containing alcohol dehydrogenase Teth39_0206 213 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 167038109 Common - phosphoribosylformylglycinamidine synthase I Teth39_1714 232 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 167038388 Common - hypothetical protein Teth39_2004 14 None None None 167036604 Common - Integrase, catalytic region Teth39_0173 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 167036672 Common - small GTP-binding protein Teth39_0245 223 COG1160 COG1160, Predicted GTPases General function prediction only 167038098 Common - biotin and thiamin synthesis associated Teth39_1703 57 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 167037249 Common - hypothetical protein Teth39_0834 9 None None None 167036642 Common - putative proton-coupled thiamine transporter YuaJ Teth39_0212 9 COG3859 COG3859, Predicted membrane protein Function unknown 167036563 Common - peptidase S51, dipeptidase E Teth39_0132 22 COG3340 PepE, Peptidase E Amino acid transport and metabolism 167036946 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_0523 102 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167037694 Common - Stage V sporulation protein S Teth39_1282 23 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 167036899 Common - ATP dependent DNA ligase Teth39_0475 109 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 167038365 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Teth39_1981 27 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 167037879 Common - Quinolinate phosphoribosyl transferase Teth39_1471 162 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 167036962 Common - protein of unknown function DUF1667 Teth39_0539 14 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 167037979 Common - LemA family protein Teth39_1577 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 167038444 Common - potassium uptake protein, TrkH family Teth39_2062 105 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 167036778 Common - glutamyl-tRNA synthetase Teth39_0351 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 167037674 Common - heat shock protein HslVU, ATPase subunit HslU Teth39_1262 213 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 167036514 Common - Type IV secretory pathway VirD4 components-like protein Teth39_0083 34 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 167036692 Common - glycoside hydrolase 15-related Teth39_0265 48 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 167038397 Common - protein of unknown function DUF214 Teth39_2013 173 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 167038017 Common - natural resistance-associated macrophage protein Teth39_1615 109 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 167037303 Common - glutamine amidotransferase of anthranilate synthase Teth39_0889 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 167038055 Common - phosphomethylpyrimidine kinase Teth39_1656 224 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 167038520 Common - nucleoside recognition domain protein Teth39_2139 43 COG0700 SpmB, Uncharacterized membrane protein Function unknown 167036948 Common - Membrane dipeptidase Teth39_0525 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 167037012 Common - oxidoreductase domain protein Teth39_0590 192 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 167038564 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Teth39_2184 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 167038286 Common - Adenosylcobinamide kinase Teth39_1895 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 167038529 Common - protein of unknown function DUF327 Teth39_2148 16 COG1728 COG1728, Uncharacterized protein conserved in bacteria Function unknown 167038524 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Teth39_2143 212 COG0313 COG0313, Predicted methyltransferases General function prediction only 167037293 Common - putative translation initiation factor, aIF-2BI family Teth39_0879 132 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 167037448 Common - histidyl-tRNA synthetase Teth39_1035 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167036615 Common - cell wall hydrolase, SleB Teth39_0184 41 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 167037785 Common - histidine triad (HIT) protein Teth39_1375 233 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 167036848 Common - Integrase, catalytic region Teth39_0423 55 None None None 167038580 Common - DNA polymerase III, subunits gamma and tau Teth39_2200 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 167036527 Common - uncharacterised conserved protein UCP033563 Teth39_0096 49 COG4198 COG4198, Uncharacterized conserved protein Function unknown 167038469 Common - integral membrane protein MviN Teth39_2088 201 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 167037828 Common - phosphatidylglycerophosphatase A Teth39_1420 13 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 167038619 Nonpathogen - hypothetical protein Teth39_2240 1 None None None 167037802 Common - chaperone protein DnaK Teth39_1393 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 167038644 Common - hypothetical protein Teth39_2265 8 None None None 167037613 Common - peptidase M16 domain protein Teth39_1201 202 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 167038543 Common - Hydantoinase/oxoprolinase Teth39_2163 120 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 167036579 Common - Integrase, catalytic region Teth39_0148 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 167037522 Common - sporulation transcriptional activator Spo0A Teth39_1109 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 167038045 Common - NAD+ synthetase Teth39_1646 226 COG0171 NadE, NAD synthase Coenzyme metabolism 167037981 Nonpathogen - hypothetical protein Teth39_1579 2 None None None 167037526 Common - hypothetical protein Teth39_1113 13 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 167037394 Common - oligoendopeptidase F Teth39_0981 86 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 167038462 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Teth39_2081 38 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 167037441 Common - (p)ppGpp synthetase I, SpoT/RelA Teth39_1028 208 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 167038075 Common - hypothetical protein Teth39_1680 8 None None None 167037238 Common - PRC-barrel domain protein Teth39_0823 15 COG1873 COG1873, Uncharacterized conserved protein Function unknown 167037077 Common - protein of unknown function DUF134 Teth39_0655 43 COG1342 COG1342, Predicted DNA-binding proteins General function prediction only 167037947 Common - protein of unknown function DUF458 Teth39_1544 15 COG1978 COG1978, Uncharacterized protein conserved in bacteria Function unknown 167038183 Common - phosphoribosyltransferase Teth39_1788 178 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 167038218 Common - hypothetical protein Teth39_1824 12 None None None 167036703 Nonpathogen - hypothetical protein Teth39_0276 2 COG3462 COG3462, Predicted membrane protein Function unknown 167036486 Nonpathogen - hypothetical protein Teth39_0055 1 None None None 167037154 Common - preprotein translocase, SecG subunit Teth39_0736 47 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 167038242 Common - peptidase M42 family protein Teth39_1849 90 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 167037116 Common - methylenetetrahydrofolate reductase Teth39_0696 142 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 167037278 Common - transglutaminase domain protein Teth39_0864 22 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 167038666 Common - NUDIX hydrolase Teth39_2287 66 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 167036767 Common - UvrB/UvrC protein Teth39_0340 19 COG3880 COG3880, Uncharacterized protein with conserved CXXC pairs Function unknown 167038330 Common - transcriptional antiterminator, BglG Teth39_1941 36 COG3711 BglG, Transcriptional antiterminator Transcription 167037939 Common - hypothetical protein Teth39_1534 6 None None None 167037126 Common - glycosyl transferase, family 2 Teth39_0707 170 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 167036520 Nonpathogen - hypothetical protein Teth39_0089 6 None None None 167037534 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Teth39_1121 52 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 167038264 Common - protein of unknown function DUF125, transmembrane Teth39_1872 26 COG1814 COG1814, Uncharacterized membrane protein Function unknown 167037644 Common - CheA signal transduction histidine kinase Teth39_1232 161 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 167037455 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Teth39_1042 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 167037837 Common - nicotinate (nicotinamide) nucleotide adenylyltransferase Teth39_1429 170 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 167036675 Common - MazG family protein Teth39_0248 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 167037988 Common - hypothetical protein Teth39_1586 24 None None None 167037142 Common - endonuclease III Teth39_0724 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 167037159 Common - protein of unknown function DUF34 Teth39_0741 135 COG0327 COG0327, Uncharacterized conserved protein Function unknown 167038223 Common - transcriptional regulator, GntR family Teth39_1829 145 COG2188 PhnF, Transcriptional regulators Transcription 167038189 Common - hypothetical protein Teth39_1794 16 COG5401 COG5401, Spore germination protein General function prediction only 167036800 Common - ribosomal protein S10 Teth39_0373 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 167037907 Nonpathogen - hypothetical protein Teth39_1500 4 None None None 167037019 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Teth39_0597 176 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 167038203 Common - pantoate--beta-alanine ligase Teth39_1809 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 167036864 Common - NADH dehydrogenase (quinone) Teth39_0439 207 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 167037911 Common - Tetrahydrodipicolinate succinyltransferase N-terminal domain protein Teth39_1504 95 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 167038197 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Teth39_1802 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 167037790 Common - hypothetical protein Teth39_1380 8 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 167038633 Common - Chromate transporter Teth39_2254 116 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 167038493 Common - Thymidine kinase Teth39_2112 95 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 167037549 Common - protein of unknown function DUF1432 Teth39_1136 18 COG4864 COG4864, Uncharacterized protein conserved in bacteria Function unknown 167036457 Common - transposase, IS605 OrfB family Teth39_0026 9 None None None 167037660 Common - protein of unknown function DUF1078 domain protein Teth39_1248 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 167037662 Common - flagellar hook capping protein Teth39_1250 115 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 167037354 Common - ABC transporter related Teth39_0941 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 167037747 Common - Asp/Glu racemase Teth39_1335 8 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 167037968 Common - Chromosome segregation ATPase-like protein Teth39_1565 57 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 167036739 Common - spore germination B3 GerAC family protein Teth39_0312 15 None None None 167036450 Common - dihydroxy-acid dehydratase Teth39_0019 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 167036654 Common - arginine biosynthesis bifunctional protein ArgJ Teth39_0224 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 167037038 Common - Alpha-mannosidase-like protein Teth39_0616 36 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 167038329 Common - phosphoenolpyruvate-dependent sugar phosphotransferase system, EIIA 2 Teth39_1940 94 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 167037359 Common - ABC transporter related Teth39_0946 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 167038624 Nonpathogen - phospholipase D/Transphosphatidylase Teth39_2245 3 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 167037584 Common - MCP methyltransferase, CheR-type Teth39_1172 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 167036853 Common - Ferritin, Dps family protein Teth39_0428 50 COG2406 COG2406, Protein distantly related to bacterial ferritins General function prediction only 167038331 Common - PTS system, mannitol-specific IIC subunit Teth39_1942 41 COG2213 MtlA, Phosphotransferase system, mannitol-specific IIBC component Carbohydrate transport and metabolism 167036813 Common - ribosomal protein L5 Teth39_0386 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 167037519 Common - arginine repressor, ArgR Teth39_1106 65 COG1438 ArgR, Arginine repressor Transcription 167036497 Common - type II secretion system protein Teth39_0066 19 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 167036684 Nonpathogen - Septum formation initiator Teth39_0257 4 None None None 167036718 Common - protein of unknown function DUF1284 Teth39_0291 18 COG3543 COG3543, Uncharacterized conserved protein Function unknown 167038511 Common - hypothetical protein Teth39_2130 11 None None None 167036449 Common - 3-isopropylmalate dehydrogenase Teth39_0018 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 167038325 Common - protein of unknown function DUF81 Teth39_1936 99 COG0730 COG0730, Predicted permeases General function prediction only 167037491 Nonpathogen - Fimbrial assembly family protein Teth39_1078 1 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 167036476 Nonpathogen - hypothetical protein Teth39_0045 1 None None None 167038122 Common - protein of unknown function DUF554 Teth39_1727 48 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 167037462 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Teth39_1049 215 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 167036460 Common - seryl-tRNA synthetase Teth39_0029 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 167036435 Common - DNA replication and repair protein RecF Teth39_0004 170 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 167038527 Common - PSP1 domain protein Teth39_2146 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 167038028 Common - dTDP-glucose 4,6-dehydratase Teth39_1628 233 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 167037918 Common - extracellular solute-binding protein, family 1 Teth39_1513 85 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 167037324 Common - nitroreductase Teth39_0911 83 COG0778 NfnB, Nitroreductase Energy production and conversion 167037992 Common - V-type H(+)-translocating pyrophosphatase Teth39_1590 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 167037658 Common - flagellar basal body-associated protein FliL Teth39_1246 16 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 167037607 Common - cell divisionFtsK/SpoIIIE Teth39_1195 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 167037844 Nonpathogen - hypothetical protein Teth39_1436 1 COG5416 COG5416, Uncharacterized integral membrane protein Function unknown 167038152 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Teth39_1757 67 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 167036545 Common - glutaredoxin-like protein, YruB-family Teth39_0114 67 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 167037243 Common - phosphate ABC transporter, inner membrane subunit PstC Teth39_0828 236 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 167036838 Common - helix-turn-helix domain protein Teth39_0411 36 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 167037755 Common - orotidine 5'-phosphate decarboxylase Teth39_1343 70 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 167037469 Common - ferric uptake regulator, Fur family Teth39_1056 207 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 167037868 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit Teth39_1460 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 167037812 Common - hypothetical protein Teth39_1403 21 None None None 167037923 Common - Monosaccharide-transporting ATPase Teth39_1518 160 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 167037535 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG family Teth39_1122 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 167038292 Common - cobyrinic acid a,c-diamide synthase Teth39_1901 138 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 167038318 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Teth39_1929 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 167037503 Nonpathogen - Stage III sporulation AC family protein Teth39_1090 3 None None None 167036594 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_0163 102 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167037518 Common - ATP-NAD/AcoX kinase Teth39_1105 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 167038314 Common - ABC transporter related Teth39_1925 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 167038271 Nonpathogen - hypothetical protein Teth39_1880 1 None None None 167036531 Common - primosome, DnaD subunit Teth39_0100 11 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 167037740 Common - major facilitator superfamily MFS_1 Teth39_1328 202 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 167037762 Common - lipoprotein signal peptidase Teth39_1350 203 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 167038112 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Teth39_1717 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 167038063 Common - ammonium transporter Teth39_1665 202 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 167037417 Common - protein of unknown function UPF0029 Teth39_1004 134 COG1739 COG1739, Uncharacterized conserved protein Function unknown 167037423 Common - CheW protein Teth39_1010 121 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 167037953 Common - hypothetical protein Teth39_1550 17 COG1655 COG1655, Uncharacterized protein conserved in bacteria Function unknown 167038033 Nonpathogen - hypothetical protein Teth39_1633 6 None None None 167036711 Common - cell wall hydrolase/autolysin Teth39_0284 185 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 167037596 Common - aminotransferase, class I and II Teth39_1184 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 167038038 Common - site-specific integrase-resolvase-like protein Teth39_1638 6 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 167037631 Common - phosphatidate cytidylyltransferase Teth39_1219 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 167036467 Nonpathogen - hypothetical protein Teth39_0036 1 None None None 167037107 Common - RNA methyltransferase, TrmA family Teth39_0686 209 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 167037042 Common - protein of unknown function DUF815 Teth39_0620 98 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 167037380 Common - putative undecaprenol kinase Teth39_0967 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 167038107 Common - amidophosphoribosyltransferase Teth39_1712 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 167036478 Nonpathogen - hypothetical protein Teth39_0047 2 None None None 167036461 Common - phage integrase family protein Teth39_0030 136 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 167036540 Common - hypothetical protein Teth39_0109 7 None None None 167038324 Nonpathogen - hypothetical protein Teth39_1935 3 COG3863 COG3863, Uncharacterized distant relative of cell wall-associated hydrolases Function unknown 167038497 Common - response regulator receiver protein Teth39_2116 20 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 167037902 Common - response regulator receiver and ANTAR domain protein Teth39_1495 201 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 167037870 Common - hypothetical protein Teth39_1462 8 None None None 167038166 Common - flagellar hook-associated 2 domain protein Teth39_1771 52 COG1345 FliD, Flagellar capping protein Cell motility and secretion 167037273 Common - molybdenum cofactor synthesis domain Teth39_0859 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 167037246 Common - phosphate uptake regulator, PhoU Teth39_0831 198 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 167037193 Common - protein of unknown function DUF523 Teth39_0776 58 COG1683 COG1683, Uncharacterized conserved protein Function unknown 167037971 Common - hypothetical protein Teth39_1568 9 None None None 167037336 Common - protein of unknown function DUF324 Teth39_0923 10 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 167037101 Common - putative signal-transduction protein with CBS and DRTGG domains Teth39_0680 168 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 167036485 Common - hypothetical protein Teth39_0054 2 None None None 167037269 Common - extracellular solute-binding protein, family 1 Teth39_0855 62 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 167038303 Nonpathogen - metal-dependent hydrolase with the TIM-barrel fold-like protein Teth39_1914 11 COG1099 COG1099, Predicted metal-dependent hydrolases with the TIM-barrel fold General function prediction only 167037761 Common - pseudouridine synthase, RluA family Teth39_1349 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 167037963 Common - pyridoxine biosynthesis protein Teth39_1560 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 167038508 Nonpathogen - hypothetical protein Teth39_2127 5 COG1433 COG1433, Uncharacterized conserved protein Function unknown 167036714 Common - pyridoxal phosphate-dependent acyltransferase, putative Teth39_0287 191 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 167036548 Common - FeS assembly protein SufB Teth39_0117 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 167037241 Common - multi-sensor signal transduction histidine kinase Teth39_0826 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 167037978 Common - phosphodiesterase, MJ0936 family Teth39_1576 48 COG0622 COG0622, Predicted phosphoesterase General function prediction only 167037485 Common - hypothetical protein Teth39_1072 3 COG4970 FimT, Tfp pilus assembly protein FimT Cell motility and secretion / Intracellular trafficking and secretion 167038548 Nonpathogen - hypothetical protein Teth39_2168 2 None None None 167038513 Nonpathogen - hypothetical protein Teth39_2132 3 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 167037727 Common - radical SAM enzyme, Cfr family Teth39_1315 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 167037617 Common - riboflavin biosynthesis protein RibF Teth39_1205 211 COG0196 RibF, FAD synthase Coenzyme metabolism 167037543 Common - chromosome segregation and condensation protein, ScpB Teth39_1130 161 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 167037655 Common - response regulator receiver protein, CheY Teth39_1243 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 167036475 Common - StbA family protein Teth39_0044 26 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 167038338 Common - PTS system transcriptional activator Teth39_1949 159 COG3933 COG3933, Transcriptional antiterminator Transcription 167037086 Common - PHP C-terminal domain protein Teth39_0665 101 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 167038422 Common - Monosaccharide-transporting ATPase Teth39_2039 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 167036663 Common - phosphoglycerate mutase 1 family Teth39_0233 158 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 167037141 Common - domain of unknown function DUF1730 Teth39_0723 140 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 167038638 Common - ATP synthase, A subunit Teth39_2259 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 167037114 Common - Glucose-6-phosphate isomerase Teth39_0694 209 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 167038603 Common - type II secretion system protein E Teth39_2224 216 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 167036524 Common - phage integrase family protein Teth39_0093 130 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 167038022 Common - lipopolysaccharide biosynthesis protein Teth39_1622 20 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 167037991 Common - positive regulator of sigma E, RseC/MucC Teth39_1589 11 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 167038347 Common - ABC transporter related Teth39_1958 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 167038328 Common - Mannitol dehydrogenase, C-terminal domain Teth39_1939 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 167037606 Common - MiaB-like tRNA modifying enzyme YliG Teth39_1194 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 167036927 Common - oxidoreductase domain protein Teth39_0503 184 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 167037980 Common - peptidase M48, Ste24p Teth39_1578 190 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 167036849 Nonpathogen - hypothetical protein Teth39_0424 5 None None None 167037355 Nonpathogen - hypothetical protein Teth39_0942 1 None None None 167036755 Common - hypothetical protein Teth39_0328 13 None None None 167037566 Common - transcriptional regulator, RpiR family Teth39_1153 94 COG1737 RpiR, Transcriptional regulators Transcription 167038535 Common - putative glucokinase, ROK family Teth39_2154 168 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 167036674 Common - Tetratricopeptide TPR_2 repeat protein Teth39_0247 55 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 167038228 Common - Formiminotransferase-cyclodeaminase Teth39_1834 38 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 167037744 Common - ABC transporter related Teth39_1332 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 167037901 Common - isoaspartyl dipeptidase Teth39_1494 40 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 167037838 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_1430 100 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167038623 Common - transcriptional regulator, XRE family Teth39_2244 34 COG1476 COG1476, Predicted transcriptional regulators Transcription 167037585 Common - RNA modification enzyme, MiaB family Teth39_1173 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 167038130 Common - two component transcriptional regulator, LytTR family Teth39_1735 221 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 167036495 Common - ATPase involved in chromosome partitioning-like protein Teth39_0064 6 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 167037492 Common - hypothetical protein Teth39_1079 5 COG3167 PilO, Tfp pilus assembly protein PilO Cell motility and secretion / Intracellular trafficking and secretion 167037031 Common - binding-protein-dependent transport systems inner membrane component Teth39_0609 136 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 167038488 Common - Sua5/YciO/YrdC/YwlC family protein Teth39_2107 242 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 167036932 Common - ABC-type uncharacterized transport system auxiliary component-like protein Teth39_0508 35 COG3225 GldG, ABC-type uncharacterized transport system involved in gliding motility, auxiliary component Cell motility and secretion 167036623 Nonpathogen - hypothetical protein Teth39_0192 1 None None None 167037933 Common - FolC bifunctional protein Teth39_1528 220 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 167038471 Common - transposase, IS605 OrfB family Teth39_2090 73 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037264 Common - Aldehyde ferredoxin oxidoreductase Teth39_0850 59 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 167037657 Common - flagellar motor switch protein FliM Teth39_1245 109 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 167036565 Common - CRISPR-associated protein Cas1 Teth39_0134 102 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 167036966 Common - dihydroxyacetone kinase, L subunit Teth39_0543 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 167038491 Common - modification methylase, HemK family Teth39_2110 235 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 167036741 Nonpathogen - hypothetical protein Teth39_0314 7 None None None 167037212 Common - aminotransferase, class V Teth39_0797 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 167036954 Nonpathogen - CRISPR-associated protein Cas4 Teth39_0531 9 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 167037554 Common - pseudouridine synthase Teth39_1141 208 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 167037064 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis protein Teth39_0642 32 COG1433 COG1433, Uncharacterized conserved protein Function unknown 167038483 Nonpathogen - hypothetical protein Teth39_2102 1 None None None 167036865 Common - hypothetical protein Teth39_0440 5 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 167038612 Common - hypothetical protein Teth39_2233 3 None None None 167037445 Common - ABC transporter related Teth39_1032 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 167037531 Common - tyrosine recombinase XerD Teth39_1118 219 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 167036648 Common - Alcohol dehydrogenase, zinc-binding domain protein Teth39_0218 178 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 167037570 Common - LamB/YcsF family protein Teth39_1157 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 167038072 Common - Altronate dehydratase Teth39_1677 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 167037156 Common - DNA primase Teth39_0738 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 167037836 Common - metal dependent phosphohydrolase Teth39_1428 42 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 167037768 Common - pyruvate, phosphate dikinase Teth39_1358 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 167037720 Common - ribosomal protein L28 Teth39_1308 53 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 167037352 Nonpathogen - hypothetical protein Teth39_0939 1 None None None 167037915 Common - cell wall hydrolase, SleB Teth39_1508 34 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 167038526 Common - Arginine deiminase Teth39_2145 59 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 167038561 Common - glycosidase, PH1107-related Teth39_2181 39 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 167038270 Common - Rhomboid family protein Teth39_1878 133 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 167038554 Common - hypothetical protein Teth39_2174 8 COG1511 COG1511, Predicted membrane protein Function unknown 167036558 Common - transposase IS116/IS110/IS902 family protein Teth39_0127 99 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037123 Nonpathogen - hypothetical protein Teth39_0703 2 None None None 167038159 Common - polar amino acid ABC transporter, inner membrane subunit Teth39_1764 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 167038410 Common - putative transcriptional regulator, AsnC family Teth39_2026 112 COG1522 Lrp, Transcriptional regulators Transcription 167037511 Common - Methenyltetrahydrofolate cyclohydrolase Teth39_1098 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 167037299 Common - protein of unknown function DUF77 Teth39_0885 24 COG0011 COG0011, Uncharacterized conserved protein Function unknown 167037944 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Teth39_1541 204 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 167037936 Common - protein of unknown function DUF151 Teth39_1531 76 COG1259 COG1259, Uncharacterized conserved protein Function unknown 167037387 Nonpathogen - hypothetical protein Teth39_0974 1 None None None 167038583 Common - lipolytic enzyme, G-D-S-L family Teth39_2204 4 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 167038668 Common - glucose inhibited division protein A Teth39_2289 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 167037451 Common - protein of unknown function DUF156 Teth39_1038 109 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 167037203 Common - GAF modulated sigma54 specific transcriptional regulator, Fis family Teth39_0788 180 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 167036453 Common - riboflavin synthase, alpha subunit Teth39_0022 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 167036892 Common - pyruvate/ketoisovalerate oxidoreductase, gamma subunit Teth39_0467 80 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 167037313 Common - transcriptional regulator, TraR/DksA family Teth39_0899 97 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 167038043 Common - ABC transporter related Teth39_1644 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 167038562 Common - glycoside hydrolase, family 5 Teth39_2182 16 COG3934 COG3934, Endo-beta-mannanase Carbohydrate transport and metabolism 167038090 Common - ATP-dependent DNA helicase PcrA Teth39_1695 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 167036444 Common - acetolactate synthase, small subunit Teth39_0013 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 167038208 Nonpathogen - hypothetical protein Teth39_1814 3 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 167037331 Nonpathogen - hypothetical protein Teth39_0918 4 None None None 167037777 Common - protein of unknown function UPF0054 Teth39_1367 188 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 167036644 Common - magnesium-translocating P-type ATPase Teth39_0214 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 167037046 Nonpathogen - hypothetical protein Teth39_0624 3 None None None 167038476 Common - sporulation transcriptional regulator SpoIIID Teth39_2095 15 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 167037892 Common - ABC-type multidrug transport system ATPase component-like protein Teth39_1485 219 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 167036509 Common - hypothetical protein Teth39_0078 27 None None None 167036697 Nonpathogen - hypothetical protein Teth39_0270 1 None None None 167038230 Common - glutamate formiminotransferase Teth39_1836 22 COG3643 COG3643, Glutamate formiminotransferase Amino acid transport and metabolism 167037686 Common - 16S rRNA processing protein RimM Teth39_1274 175 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 167036904 Common - hybrid cluster protein Teth39_0480 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 167036773 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Teth39_0346 194 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 167038190 Common - integral membrane sensor signal transduction histidine kinase Teth39_1795 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 167036921 Common - Rubredoxin-type Fe(Cys)4 protein Teth39_0497 124 COG1773 COG1773, Rubredoxin Energy production and conversion 167036914 Common - protein of unknown function DUF161 Teth39_0490 48 COG1284 COG1284, Uncharacterized conserved protein Function unknown 167036515 Common - hypothetical protein Teth39_0084 19 None None None 167037501 Common - AAA ATPase Teth39_1088 32 COG3854 SpoIIIAA, ncharacterized protein conserved in bacteria Function unknown 167038039 Common - protein of unknown function DUF1703 Teth39_1639 12 None None None 167036505 Nonpathogen - hypothetical protein Teth39_0074 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 167036634 Common - aldo/keto reductase Teth39_0204 200 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 167038201 Common - oxidoreductase domain protein Teth39_1807 59 COG5495 COG5495, Uncharacterized conserved protein Function unknown 167038007 Common - hypothetical protein Teth39_1605 6 COG2445 COG2445, Uncharacterized conserved protein Function unknown 167037882 Common - DNA polymerase I Teth39_1474 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 167037922 Common - beta-phosphoglucomutase Teth39_1517 178 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 167037862 Common - maf protein Teth39_1454 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 167038391 Common - aromatic amino acid beta-eliminating lyase/threonine aldolase Teth39_2007 128 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 167036677 Common - RNA-binding S4 domain protein Teth39_0250 37 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 167037256 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Teth39_0841 213 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 167037425 Common - crossover junction endodeoxyribonuclease RuvC Teth39_1012 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 167036990 Common - 2-phosphosulfolactate phosphatase Teth39_0568 47 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 167038432 Common - oxidoreductase domain protein Teth39_2050 119 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 167037889 Nonpathogen - prevent-host-death family protein Teth39_1481 2 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 167038015 Common - Nucleotide binding protein, PINc Teth39_1613 27 COG1569 COG1569, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 167038661 Common - hypothetical protein Teth39_2282 13 None None None 167037333 Nonpathogen - protein of unknown function DUF324 Teth39_0920 9 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 167036492 Common - peptidase M23B Teth39_0061 195 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 167038253 Nonpathogen - copper amine oxidase domain protein Teth39_1861 7 None None None 167038373 Common - glycine cleavage system H protein Teth39_1989 188 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 167037875 Common - Lytic transglycosylase, catalytic Teth39_1467 181 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 167037573 Common - protein of unknown function DUF1445 Teth39_1160 41 COG4336 COG4336, Uncharacterized conserved protein Function unknown 167037726 Common - protein serine/threonine phosphatase Teth39_1314 137 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 167036789 Common - ribosomal protein L11 Teth39_0362 249 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 167037818 Common - protein of unknown function DUF1393 Teth39_1409 17 COG4720 COG4720, Predicted membrane protein Function unknown 167037677 Common - DNA protecting protein DprA Teth39_1265 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 167038355 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Teth39_1970 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 167038656 Common - MscS Mechanosensitive ion channel Teth39_2277 229 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 167037014 Common - Xylose isomerase domain protein TIM barrel Teth39_0592 67 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 167036879 Common - Osmosensitive K+ channel histidine kinase-like protein Teth39_0454 30 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 167038086 Common - glutamyl-tRNA(Gln) amidotransferase, B subunit Teth39_1691 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 167036613 Common - spore germination B3 GerAC family protein Teth39_0182 15 None None None 167036897 Common - protein of unknown function DUF6, transmembrane Teth39_0473 46 COG2510 COG2510, Predicted membrane protein Function unknown 167037869 Common - PHP C-terminal domain protein Teth39_1461 31 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 167037734 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Teth39_1322 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 167036972 Common - integral membrane protein TIGR01906 Teth39_0550 11 COG4478 COG4478, Predicted membrane protein Function unknown 167037921 Common - transcriptional regulator, LacI family Teth39_1516 130 COG1609 PurR, Transcriptional regulators Transcription 167036578 Common - CTP synthase Teth39_0147 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 167038121 Common - hypothetical protein Teth39_1726 10 None None None 167038370 Common - dihydrolipoamide dehydrogenase Teth39_1986 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 167037615 Common - Polyribonucleotide nucleotidyltransferase Teth39_1203 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 167037781 Common - protein of unknown function DUF1429 Teth39_1371 15 None None None 167038049 Common - ATP-dependent Clp protease, ATP-binding subunit ClpX Teth39_1650 211 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 167037341 Common - helicase domain protein Teth39_0928 230 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 167036721 Common - putative transmembrane anti-sigma factor Teth39_0294 7 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 167036872 Common - cell wall hydrolase/autolysin Teth39_0447 124 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 167037696 Common - Ribonuclease III Teth39_1284 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 167037701 Common - 2-nitropropane dioxygenase, NPD Teth39_1289 149 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 167037821 Common - hypothetical protein Teth39_1412 4 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167037474 Common - O-methyltransferase, family 3 Teth39_1061 111 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 167036669 Common - FMN-binding domain protein Teth39_0241 12 COG4939 COG4939, Major membrane immunogen, membrane-anchored lipoprotein Function unknown 167036662 Common - hypothetical protein Teth39_0232 8 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 167037057 Nonpathogen - hypothetical protein Teth39_0635 1 None None None 167036792 Common - ribosomal protein L7/L12 Teth39_0365 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 167038248 Nonpathogen - hypothetical protein Teth39_1855 1 None None None 167037066 Common - beta-lactamase domain protein Teth39_0644 57 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 167038364 Common - hypothetical protein Teth39_1980 18 COG4821 COG4821, Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain General function prediction only 167037050 Common - sucrose-6-phosphate hydrolase Teth39_0628 54 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 167038646 Common - transcriptional regulator, Crp/Fnr family Teth39_2267 172 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 167037211 Common - protein of unknown function DUF156 Teth39_0796 91 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 167038559 Common - Nucleotidyl transferase Teth39_2179 239 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 167037025 Common - galactokinase Teth39_0603 102 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 167036554 Common - CRISPR-associated protein, Csh2 family Teth39_0123 55 COG3649 COG3649, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 167038199 Common - hypothetical protein Teth39_1804 8 COG5609 COG5609, Uncharacterized conserved protein Function unknown 167037884 Nonpathogen - hypothetical protein Teth39_1476 1 None None None 167037669 Common - flagellar M-ring protein FliF Teth39_1257 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 167038349 Common - putative CoA-substrate-specific enzyme activase Teth39_1960 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 167037685 Common - tRNA (guanine-N1)-methyltransferase Teth39_1273 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 167037466 Common - protein of unknown function DUF965 Teth39_1053 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 167036439 Common - domain of unknown function DUF1727 Teth39_0008 139 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 167036825 Common - ribosomal protein L36 Teth39_0398 136 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 167036686 Common - Ppx/GppA phosphatase Teth39_0259 183 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 167036802 Common - ribosomal protein L4/L1e Teth39_0375 217 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 167038040 Common - protein of unknown function DUF1703 Teth39_1640 12 None None None 167038210 Nonpathogen - Citrate transporter Teth39_1816 8 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 167037580 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase Teth39_1168 186 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 167038182 Common - hypothetical protein Teth39_1787 9 None None None 167037430 Common - queuine tRNA-ribosyltransferase Teth39_1017 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 167037224 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Teth39_0809 213 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 167036764 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)) Teth39_0337 202 COG0281 SfcA, Malic enzyme Energy production and conversion 167037635 Common - uridylate kinase Teth39_1223 245 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 167038533 Nonpathogen - hypothetical protein Teth39_2152 3 None None None 167038171 Common - Type II site-specific deoxyribonuclease Teth39_1776 10 None None None 167036728 Common - ATP-dependent metalloprotease FtsH Teth39_0301 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 167036518 Nonpathogen - DNA binding domain, excisionase family Teth39_0087 2 None None None 167037373 Common - hydrolase or acyltransferase (alpha/beta hydrolase superfamily)-like protein Teth39_0960 26 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 167037956 Common - Protein-tyrosine-phosphatase Teth39_1553 40 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 167038441 Common - xylulokinase Teth39_2059 185 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 167037555 Nonpathogen - hypothetical protein Teth39_1142 1 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 167038085 Nonpathogen - hypothetical protein Teth39_1690 1 None None None 167036987 Common - peptidase M23B Teth39_0565 192 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 167038448 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Teth39_2066 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 167037487 Nonpathogen - hypothetical protein Teth39_1074 2 COG4966 PilW, Tfp pilus assembly protein PilW Cell motility and secretion / Intracellular trafficking and secretion 167037480 Common - type II secretion system protein E Teth39_1067 221 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 167036804 Common - ribosomal protein L2 Teth39_0377 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 167037089 Common - alpha amylase, catalytic region Teth39_0668 165 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 167038578 Common - recombination protein RecR Teth39_2198 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 167037798 Nonpathogen - hypothetical protein Teth39_1388 1 None None None 167038628 Common - FAD dependent oxidoreductase Teth39_2249 83 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 167037710 Common - nucleoside recognition domain protein Teth39_1298 25 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 167036534 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Teth39_0103 213 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 167036956 Nonpathogen - hypothetical protein Teth39_0533 1 None None None 167037716 Common - degV family protein Teth39_1304 57 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 167037479 Common - shikimate 5-dehydrogenase Teth39_1066 226 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 167037627 Common - glycosyl transferase, family 2 Teth39_1215 205 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 167037016 Common - transposase IS116/IS110/IS902 family protein Teth39_0594 58 None None None 167037408 Common - thioredoxin Teth39_0995 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 167037185 Common - ribosomal protein L35 Teth39_0768 100 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 167036571 Common - Homoserine dehydrogenase Teth39_0140 218 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 167038463 Common - PTS system transcriptional activator Teth39_2082 178 COG3933 COG3933, Transcriptional antiterminator Transcription 167037304 Common - anthranilate phosphoribosyltransferase Teth39_0890 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 167037800 Common - ribosomal protein L11 methyltransferase Teth39_1391 180 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 167038405 Nonpathogen - hypothetical protein Teth39_2021 10 None None None 167038495 Common - transcription termination factor Rho Teth39_2114 211 COG1158 Rho, Transcription termination factor Transcription 167037395 Common - 3-dehydroquinate synthase Teth39_0982 213 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 167037437 Common - protein-export membrane protein SecF Teth39_1024 212 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 167038599 Nonpathogen - hypothetical protein Teth39_2220 1 None None None 167038545 Common - permease for cytosine/purines, uracil, thiamine, allantoin Teth39_2165 70 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 167036902 Common - hypothetical protein Teth39_0478 7 COG1971 COG1971, Predicted membrane protein Function unknown 167037218 Common - peptidase M16 domain protein Teth39_0803 120 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 167037965 Common - protein of unknown function DUF86 Teth39_1562 35 COG2445 COG2445, Uncharacterized conserved protein Function unknown 167036798 Common - translation elongation factor G Teth39_0371 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 167038672 Common - protein of unknown function DUF37 Teth39_2293 185 COG0759 COG0759, Uncharacterized conserved protein Function unknown 167037368 Common - pyrrolidone-carboxylate peptidase Teth39_0955 52 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 167038342 Common - PfkB domain protein Teth39_1953 135 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 167036582 Common - 1-phosphofructokinase Teth39_0151 104 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 167037707 Common - acetate kinase Teth39_1295 162 COG0282 ackA, Acetate kinase Energy production and conversion 167037076 Common - anaerobic ribonucleoside-triphosphate reductase activating protein Teth39_0654 67 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 167036583 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Teth39_0152 140 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 167036437 Common - Alpha-glucosidase Teth39_0006 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 167037349 Common - ABC transporter related Teth39_0936 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 167037809 Common - hypothetical protein Teth39_1400 9 COG4975 GlcU, Putative glucose uptake permease Carbohydrate transport and metabolism 167038301 Common - SUF system FeS assembly protein, NifU family Teth39_1910 168 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 167038066 Common - hypothetical protein Teth39_1669 29 None None None 167037515 Common - hypothetical protein Teth39_1102 12 None None None 167036493 Nonpathogen - hypothetical protein Teth39_0062 1 None None None 167037361 Nonpathogen - hypothetical protein Teth39_0948 1 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 167038621 Common - excision promoter, Xis Teth39_2242 4 COG3311 AlpA, Predicted transcriptional regulator Transcription 167037541 Common - peptidase M50 Teth39_1128 95 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 167037640 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG Teth39_1228 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 167036806 Common - ribosomal protein L22 Teth39_0379 229 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 167037653 Common - flagellar biosynthetic protein FliP Teth39_1241 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 167037483 Nonpathogen - Tfp pilus assembly protein PilE-like protein Teth39_1070 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 167038013 Common - hypothetical protein Teth39_1611 9 None None None 167036814 Common - ribosomal protein S14 Teth39_0387 204 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 167036688 Common - extracellular solute-binding protein, family 1 Teth39_0261 127 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 167038601 Nonpathogen - hypothetical protein Teth39_2222 2 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 167037864 Common - hydrogenase, Fe-only Teth39_1456 182 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 167037084 Nonpathogen - hypothetical protein Teth39_0663 2 None None None 167037941 Common - integral membrane sensor signal transduction histidine kinase Teth39_1536 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 167038607 Nonpathogen - hypothetical protein Teth39_2228 1 None None None 167038295 Common - periplasmic binding protein Teth39_1904 190 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 167037731 Common - methionyl-tRNA formyltransferase Teth39_1319 227 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 167038226 Common - ABC transporter related Teth39_1832 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 167036756 Common - ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent Teth39_0329 223 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 167037074 Common - hypothetical protein Teth39_0652 16 COG4887 COG4887, Uncharacterized metal-binding protein conserved in archaea General function prediction only 167038287 Common - putative L-threonine-O-3-phosphate decarboxylase Teth39_1896 237 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 167036896 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Teth39_0472 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 167038024 Common - Undecaprenyl-phosphate galactose phosphotransferase Teth39_1624 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 167036724 Nonpathogen - hypothetical protein Teth39_0297 1 None None None 167038206 Nonpathogen - hypothetical protein Teth39_1812 2 None None None 167038336 Common - YdjC family protein Teth39_1947 47 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 167037587 Common - DNA mismatch repair protein MutL Teth39_1175 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 167037458 Common - hypothetical protein Teth39_1045 22 COG4403 LcnDR2, Lantibiotic modifying enzyme Defense mechanisms 167037033 Common - Beta-galactosidase Teth39_0611 75 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 167036542 Common - hypothetical protein Teth39_0111 10 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 167037998 Common - hypothetical protein Teth39_1596 18 COG4925 COG4925, Uncharacterized conserved protein Function unknown 167038517 Common - hydrolase, TatD family Teth39_2136 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 167036834 Common - tRNA pseudouridine synthase A Teth39_0407 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 167037148 Common - transcriptional regulator, DeoR family Teth39_0730 61 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 167037198 Common - hypothetical protein Teth39_0783 3 None None None 167038412 Common - N-acetylglucosamine-6-phosphate deacetylase Teth39_2028 134 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 167037599 Common - metallophosphoesterase Teth39_1187 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 167036466 Nonpathogen - hypothetical protein Teth39_0035 1 None None None 167036656 Common - acetylornithine and succinylornithine aminotransferase Teth39_0226 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 167037040 Common - Acetamidase/Formamidase Teth39_0618 54 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 167038608 Common - peptidase M23B Teth39_2229 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 167036855 Common - hypothetical protein Teth39_0430 5 None None None 167038094 Common - phosphotransferase system, lactose/cellobiose-specific IIB subunit Teth39_1699 30 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 167038221 Common - phosphopentomutase Teth39_1827 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 167037931 Common - hypothetical protein Teth39_1526 70 COG3391 COG3391, Uncharacterized conserved protein Function unknown 167038648 Common - ribosomal protein L9 Teth39_2269 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 167037973 Common - natural resistance-associated macrophage protein Teth39_1570 110 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 167038614 Nonpathogen - hypothetical protein Teth39_2235 1 None None None 167037983 Common - addiction module toxin, Txe/YoeB family Teth39_1581 10 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 167038499 Common - protein of unknown function DUF1312 Teth39_2118 15 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 167038037 Nonpathogen - hypothetical protein Teth39_1637 2 None None None 167038506 Common - Microtubule-severing ATPase Teth39_2125 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 167037049 Common - binding-protein-dependent transport systems inner membrane component Teth39_0627 163 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 167038239 Common - hypothetical protein Teth39_1845 3 None None None 167038576 Common - CrcB protein Teth39_2196 6 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 167037267 Common - UBA/THIF-type NAD/FAD binding protein Teth39_0853 216 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 167038515 Common - dimethyladenosine transferase Teth39_2134 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 167037220 Common - S-adenosyl-methyltransferase MraW Teth39_0805 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 167037334 Common - protein of unknown function DUF324 Teth39_0921 10 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 167038305 Common - oxidoreductase FAD/NAD(P)-binding domain protein Teth39_1916 141 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 167038346 Common - conserved hypothetical protein 245 Teth39_1957 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 167036705 Common - heavy metal translocating P-type ATPase Teth39_0278 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 167037729 Common - peptidase, membrane zinc metallopeptidase, putative Teth39_1317 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 167038568 Common - transcriptional regulator, LacI family Teth39_2188 124 COG1609 PurR, Transcriptional regulators Transcription 167037432 Nonpathogen - hypothetical protein Teth39_1019 3 None None None 167038552 Common - PP-loop domain protein Teth39_2172 93 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 167038649 Common - phosphoesterase, RecJ domain protein Teth39_2270 68 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 167038424 Common - RbsD or FucU transport Teth39_2041 44 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 167037825 Common - Integrase, catalytic region Teth39_1417 55 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 167038585 Common - AAA ATPase Teth39_2206 70 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 167038663 Common - parB-like partition protein Teth39_2284 188 COG1475 Spo0J, Predicted transcriptional regulators Transcription 167037327 Common - transposase IS116/IS110/IS902 family protein Teth39_0914 99 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 167038269 Common - Auxin Efflux Carrier Teth39_1877 146 COG0679 COG0679, Predicted permeases General function prediction only 167038151 Common - hypothetical protein Teth39_1756 7 None None None 167038465 Nonpathogen - prevent-host-death family protein Teth39_2084 6 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 167038009 Common - Chromosome segregation ATPase-like protein Teth39_1607 59 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 167037391 Nonpathogen - hypothetical protein Teth39_0978 1 None None None 167037398 Common - Prephenate dehydrogenase Teth39_0985 157 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 167037200 Common - dihydrolipoamide dehydrogenase Teth39_0785 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 167038058 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Teth39_1659 155 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 167037856 Common - septum site-determining protein MinC Teth39_1448 67 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 167037899 Common - protein of unknown function DUF583 Teth39_1492 92 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 167037524 Common - hypothetical protein Teth39_1111 7 None None None 167037942 Common - NCAIR mutase (PurE)-related protein-like protein Teth39_1539 67 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 167038105 Common - phosphoribosylglycinamide formyltransferase Teth39_1710 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 167037647 Common - Cobyrinic acid a,c-diamide synthase Teth39_1235 113 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 167037090 Common - extracellular solute-binding protein, family 1 Teth39_0669 93 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 167037297 Nonpathogen - hypothetical protein Teth39_0883 4 None None None 167037498 Common - peptidase M24 Teth39_1085 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 167037262 Common - Integrase, catalytic region Teth39_0847 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 167036568 Common - beta-lactamase domain protein Teth39_0137 63 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 167037577 Nonpathogen - hypothetical protein Teth39_1165 1 None None None 167037275 Common - molybdenum cofactor biosynthesis protein A Teth39_0861 206 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 167036890 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Teth39_0465 122 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 167037044 Common - extracellular solute-binding protein, family 1 Teth39_0622 46 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 167038110 Common - phosphoribosylformylglycinamidine synthase, purS Teth39_1715 117 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 167036775 Common - 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Teth39_0348 185 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 167037562 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Teth39_1149 62 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 167038631 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Teth39_2252 244 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 167037788 Common - methyl-accepting chemotaxis sensory transducer Teth39_1378 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 167037439 Common - single-stranded-DNA-specific exonuclease RecJ Teth39_1026 206 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 167037741 Nonpathogen - hypothetical protein Teth39_1329 9 None None None 167038051 Common - trigger factor Teth39_1652 216 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 167037896 Nonpathogen - hypothetical protein Teth39_1489 2 None None None 167037411 Common - Vitamin B12 dependent methionine synthase, activation region Teth39_0998 50 COG3894 COG3894, Uncharacterized metal-binding protein General function prediction only 167038215 Common - transcriptional antiterminator, BglG Teth39_1821 29 COG3711 BglG, Transcriptional antiterminator Transcription 167037926 Common - Kojibiose phosphorylase Teth39_1521 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 167036860 Common - hypothetical protein Teth39_0435 21 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 167037830 Common - Serine-type D-Ala-D-Ala carboxypeptidase Teth39_1422 156 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 167037178 Common - hypothetical protein Teth39_0761 3 None None None 167037510 Common - NusB antitermination factor Teth39_1097 175 COG0781 NusB, Transcription termination factor Transcription 167037917 Common - Kojibiose phosphorylase Teth39_1512 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 167038192 Common - transcriptional regulator, LacI family Teth39_1797 129 COG1609 PurR, Transcriptional regulators Transcription 167037934 Common - GCN5-related N-acetyltransferase Teth39_1529 103 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 167036964 Common - sigma54 specific transcriptional regulator, Fis family Teth39_0541 170 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 167038277 Common - cobalamin biosynthesis protein CbiM Teth39_1886 70 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 167038163 Common - methyl-accepting chemotaxis sensory transducer with Cache sensor Teth39_1768 156 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 167037722 Common - thiamine pyrophosphokinase Teth39_1310 50 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 167036867 Common - MazG nucleotide pyrophosphohydrolase Teth39_0442 9 COG1694 MazG, Predicted pyrophosphatase General function prediction only 167037175 Common - Hsp33 protein Teth39_0758 128 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 167037112 Common - peptidase T Teth39_0692 56 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 167038262 Common - Integrase, catalytic region Teth39_1870 55 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037350 Common - transcriptional regulator, XRE family Teth39_0937 5 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 167037234 Common - cell division protein FtsZ Teth39_0819 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 167037959 Common - UTP-glucose-1-phosphate uridylyltransferase Teth39_1556 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 167036820 Common - preprotein translocase, SecY subunit Teth39_0393 242 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 167036665 Common - protein of unknown function DUF1312 Teth39_0236 15 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 167038018 Common - phosphodiesterase, MJ0936 family Teth39_1616 42 COG0622 COG0622, Predicted phosphoesterase General function prediction only 167037158 Common - protein of unknown function DUF633 Teth39_0740 33 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 167037569 Common - natural resistance-associated macrophage protein Teth39_1156 113 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 167037834 Common - YheO domain protein Teth39_1426 50 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 167038070 Common - type III effector Hrp-dependent outers Teth39_1675 74 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 167038308 Common - LemA family protein Teth39_1919 132 COG1704 LemA, Uncharacterized conserved protein Function unknown 167036483 Common - TRAG family protein Teth39_0052 77 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 167038237 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Teth39_1843 67 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 167036832 Common - ABC transporter related Teth39_0405 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 167038088 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Teth39_1693 183 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 167036877 Nonpathogen - hypothetical protein Teth39_0452 1 None None None 167036785 Common - translation elongation factor Tu Teth39_0358 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 167036561 Common - transposase IS116/IS110/IS902 family protein Teth39_0130 99 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 167036622 Common - Zn-dependent hydrolase of the beta-lactamase fold-like protein Teth39_0191 100 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 167038321 Common - binding-protein-dependent transport systems inner membrane component Teth39_1932 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 167037698 Common - acyl carrier protein Teth39_1286 195 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 167036958 Common - MIP family channel protein Teth39_0535 133 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 167038658 Common - cyanophycin synthetase Teth39_2279 206 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 167036975 Common - cell division protein FtsA Teth39_0553 152 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 167036782 Common - RNA methyltransferase, TrmH family, group 3 Teth39_0355 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 167036601 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Teth39_0170 178 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 167036690 Common - binding-protein-dependent transport systems inner membrane component Teth39_0263 154 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 167038651 Nonpathogen - hypothetical protein Teth39_2272 4 None None None 167037121 Nonpathogen - hypothetical protein Teth39_0701 3 None None None 167038371 Common - lipoyltransferase and lipoate-protein ligase Teth39_1987 86 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 167036639 Common - transcriptional regulator, TrmB Teth39_0209 96 COG1846 MarR, Transcriptional regulators Transcription 167038368 Common - aminotransferase, class I and II Teth39_1984 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 167036870 Common - thioredoxin reductase Teth39_0445 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 167036794 Common - DNA-directed RNA polymerase, beta' subunit Teth39_0367 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 167037018 Common - transcriptional regulator, DeoR family Teth39_0596 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 167036629 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Teth39_0198 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 167038047 Common - small GTP-binding protein Teth39_1648 198 COG0218 COG0218, Predicted GTPase General function prediction only 167037472 Common - protein of unknown function DUF988 Teth39_1059 19 COG4708 COG4708, Predicted membrane protein Function unknown 167037347 Common - hypothetical protein Teth39_0934 7 None None None 167036490 Common - hypothetical protein Teth39_0059 5 None None None 167038246 Nonpathogen - hypothetical protein Teth39_1853 7 None None None 167038001 Nonpathogen - hypothetical protein Teth39_1599 7 None None None 167037787 Common - diguanylate cyclase with PAS/PAC sensor Teth39_1377 181 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 167037850 Common - peptidase M50 Teth39_1442 81 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 167036442 Common - DNA gyrase, A subunit Teth39_0011 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 167036919 Common - Na+/H+ antiporter NhaC Teth39_0495 54 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 167036885 Common - Phosphate butyryltransferase Teth39_0460 152 COG0280 Pta, Phosphotransacetylase Energy production and conversion 167036723 Common - protein of unknown function DUF6, transmembrane Teth39_0296 170 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 167037823 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Teth39_1414 209 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 167036507 Nonpathogen - peptidase A24A, prepilin type IV Teth39_0076 1 None None None 167038478 Common - SpoIID/LytB domain Teth39_2097 43 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 167037974 Common - positive regulator of sigma E, RseC/MucC Teth39_1571 4 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 167038137 Common - putative metalloendopeptidase, glycoprotease family Teth39_1742 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 167037690 Common - putative helix-turn-helix protein, YlxM/p13 family protein Teth39_1278 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 167037894 Common - hypothetical protein Teth39_1487 6 None None None 167037858 Common - hypothetical protein Teth39_1450 12 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 167038426 Common - transcriptional regulator, LacI family Teth39_2043 132 COG1609 PurR, Transcriptional regulators Transcription 167036632 Common - extracellular solute-binding protein, family 5 Teth39_0202 215 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 167037173 Common - Silent information regulator protein Sir2 Teth39_0756 151 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 167038165 Common - flagellar protein FliS Teth39_1770 88 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 167036912 Common - putative transcriptional regulator, CopG family Teth39_0488 15 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 167036503 Nonpathogen - hypothetical protein Teth39_0072 4 None None None 167038454 Common - major facilitator superfamily MFS_1 Teth39_2072 57 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 167036938 Common - ATP phosphoribosyltransferase Teth39_0515 211 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 167037671 Common - flagellar basal-body rod protein FlgC Teth39_1259 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 167037230 Common - Polypeptide-transport-associated domain protein, FtsQ-type Teth39_0815 31 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 167036646 Common - glutamate synthase (NADPH), homotetrameric Teth39_0216 204 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 167037679 Common - protein of unknown function UPF0102 Teth39_1267 149 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 167038385 Common - glycogen synthase Teth39_2001 232 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 167037714 Common - small acid-soluble spore protein, alpha/beta type Teth39_1302 15 None None None 167038354 Common - transcriptional regulator, ArsR family Teth39_1968 172 COG0640 ArsR, Predicted transcriptional regulators Transcription 167038485 Common - uracil phosphoribosyltransferase Teth39_2104 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 167037095 Common - hypothetical protein Teth39_0674 28 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 167038531 Common - dTMP kinase Teth39_2150 231 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 167036608 Common - transcriptional regulator, GntR family Teth39_0177 130 COG1802 GntR, Transcriptional regulators Transcription 167038361 Nonpathogen - hypothetical protein Teth39_1977 11 COG3875 COG3875, Uncharacterized conserved protein Function unknown 167036992 Common - excinuclease ABC, A subunit Teth39_0570 247 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 167037751 Common - Peptidoglycan-binding domain 1 protein Teth39_1339 52 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 167037413 Common - SpoIID/LytB domain Teth39_1000 59 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 167037277 Common - MOSC domain containing protein Teth39_0863 41 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 167037629 Common - putative membrane-associated zinc metalloprotease Teth39_1217 208 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 167036591 Common - SpoVG family protein Teth39_0160 24 COG2088 SpoVG, Uncharacterized protein, involved in the regulation of septum location Cell envelope biogenesis, outer membrane 167036944 Common - imidazoleglycerol phosphate synthase, cyclase subunit Teth39_0521 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 167037378 Common - major facilitator superfamily MFS_1 Teth39_0965 62 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 167036536 Nonpathogen - hypothetical protein Teth39_0105 2 None None None 167038297 Nonpathogen - hypothetical protein Teth39_1906 1 None None None 167037384 Common - protein of unknown function DUF1294 Teth39_0971 37 COG3326 COG3326, Predicted membrane protein Function unknown 167036585 Nonpathogen - hypothetical protein Teth39_0154 5 None None None 167038258 Common - hypothetical protein Teth39_1866 4 None None None 167038140 Common - protein of unknown function UPF0079 Teth39_1745 208 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 167038251 Nonpathogen - Peptidase M15A Teth39_1859 1 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 167037287 Common - hypothetical protein Teth39_0873 14 None None None 167037738 Common - domain of unknown function DUF1732 Teth39_1326 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 167038414 Common - protein of unknown function DUF820 Teth39_2031 36 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 167037477 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG family Teth39_1064 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 167038280 Common - Porphobilinogen synthase Teth39_1889 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 167037183 Common - Chorismate synthase Teth39_0766 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 167037796 Common - transposase, IS204/IS1001/IS1096/IS1165 family protein Teth39_1386 57 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037807 Nonpathogen - hypothetical protein Teth39_1398 1 None None None 167036980 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Teth39_0558 188 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 167037397 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Teth39_0984 185 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 167038674 Common - ribosomal protein L34 Teth39_2295 194 None None None 167037771 Common - glycyl-tRNA synthetase Teth39_1361 88 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 167037306 Common - Phosphoribosylanthranilate isomerase Teth39_0892 198 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 167038597 Common - hypothetical protein Teth39_2218 19 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 167037759 Common - Uracil phosphoribosyltransferase Teth39_1347 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 167036910 Common - Outer membrane lipoprotein-sorting protein-like protein Teth39_0486 5 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 167036844 Common - Transcriptional activator of acetoin/glycerol metabolism-like protein Teth39_0419 39 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 167037216 Common - hypothetical protein Teth39_0801 10 None None None 167037709 Common - protein of unknown function DUF795 Teth39_1297 28 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 167037849 Common - Radical SAM domain protein Teth39_1441 75 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 167036763 Common - translation elongation factor G Teth39_0336 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 167038340 Common - hypothetical protein Teth39_1951 6 None None None 167036611 Common - GerA spore germination protein Teth39_0180 15 None None None 167037928 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Teth39_1523 143 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 167038143 Common - ornithine carbamoyltransferase Teth39_1748 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 167037571 Common - Allophanate hydrolase subunit 1 Teth39_1158 115 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 167037779 Common - PhoH family protein Teth39_1369 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 167036463 Common - transcriptional regulator, XRE family Teth39_0032 41 COG1395 COG1395, Predicted transcriptional regulator Transcription 167037001 Common - AMP-dependent synthetase and ligase Teth39_0579 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 167036734 Common - biotin/lipoyl attachment domain-containing protein Teth39_0307 212 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 167037023 Nonpathogen - hypothetical protein Teth39_0601 16 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 167038557 Common - hypothetical protein Teth39_2177 21 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 167037568 Common - Citrate transporter Teth39_1155 137 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 167037051 Nonpathogen - hypothetical protein Teth39_0629 5 None None None 167037127 Common - protein of unknown function DUF205 Teth39_0708 108 COG0344 COG0344, Predicted membrane protein Function unknown 167037600 Common - metal dependent phosphohydrolase Teth39_1188 79 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 167036841 Common - protein of unknown function DUF990 Teth39_0414 20 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 167037667 Common - Flagellar biosynthesis/type III secretory pathway protein-like protein Teth39_1255 27 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 167037314 Common - protein of unknown function UPF0047 Teth39_0900 119 COG0432 COG0432, Uncharacterized conserved protein Function unknown 167037464 Common - protein of unknown function UPF0118 Teth39_1051 210 COG0628 PerM, Predicted permease General function prediction only 167037842 Common - protein of unknown function DUF464 Teth39_1434 23 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 167038178 Common - flagellar hook-associated protein 3 Teth39_1783 108 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 167037401 Common - cell wall hydrolase, SleB Teth39_0988 80 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 167038083 Common - binding-protein-dependent transport systems inner membrane component Teth39_1688 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 167036521 Nonpathogen - hypothetical protein Teth39_0090 1 None None None 167037816 Common - beta-lactamase domain protein Teth39_1407 86 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 167037371 Common - intracellular protease, PfpI family Teth39_0958 160 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 167038212 Common - hypothetical protein Teth39_1818 14 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 167036827 Common - ribosomal protein S11 Teth39_0400 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 167037421 Common - cysteine synthase A Teth39_1008 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 167036985 Common - cell division ATP-binding protein FtsE Teth39_0563 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 167038594 Nonpathogen - hypothetical protein Teth39_2215 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 167037886 Nonpathogen - hypothetical protein Teth39_1478 6 None None None 167038434 Common - Resolvase, N-terminal domain Teth39_2052 22 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 167036881 Common - transposase IS116/IS110/IS902 family protein Teth39_0456 58 None None None 167037258 Nonpathogen - hypothetical protein Teth39_0843 1 None None None 167037633 Nonpathogen - hypothetical protein Teth39_1221 1 None None None 167037021 Nonpathogen - hypothetical protein Teth39_0599 8 None None None 167038407 Common - ABC transporter related Teth39_2023 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 167037069 Common - periplasmic binding protein Teth39_0647 91 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 167037508 Common - hypothetical protein Teth39_1095 12 None None None 167037954 Common - hypothetical protein Teth39_1551 20 COG3949 COG3949, Uncharacterized membrane protein Function unknown 167038184 Common - helicase, RecD/TraA family Teth39_1789 148 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 167038134 Common - MotA/TolQ/ExbB proton channel Teth39_1739 111 COG1291 MotA, Flagellar motor component Cell motility and secretion 167037557 Common - putative agmatinase Teth39_1144 138 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 167036995 Common - Peptidoglycan glycosyltransferase Teth39_0573 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 167037168 Common - prolipoprotein diacylglyceryl transferase Teth39_0751 205 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 167037087 Common - uncharacterised P-loop ATPase protein UPF0042 Teth39_0666 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 167036868 Nonpathogen - hypothetical protein Teth39_0443 1 None None None 167036940 Common - histidinol-phosphate aminotransferase Teth39_0517 241 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 167037418 Common - CoA-binding domain protein Teth39_1005 129 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 167037456 Common - hypothetical protein Teth39_1043 7 None None None 167038202 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Teth39_1808 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 167038461 Common - response regulator receiver protein Teth39_2080 18 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 167038586 Common - Integrase, catalytic region Teth39_2207 55 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 167036857 Common - amino acid carrier protein Teth39_0432 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 167037145 Common - Cof-like hydrolase Teth39_0727 150 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 167036670 Common - desulfoferrodoxin Teth39_0242 34 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 167038076 Common - phosphodiesterase, MJ0936 family Teth39_1681 70 COG0622 COG0622, Predicted phosphoesterase General function prediction only 167038523 Common - cation diffusion facilitator family transporter Teth39_2142 208 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 167037440 Common - adenine phosphoribosyltransferase Teth39_1027 177 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 167037239 Common - ATP-cone domain protein Teth39_0824 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 167037447 Common - transcriptional regulator, MarR family Teth39_1034 123 COG1846 MarR, Transcriptional regulators Transcription 167037643 Common - CheW protein Teth39_1231 130 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 167037987 Common - ATPase associated with various cellular activities, AAA_5 Teth39_1585 44 COG0714 COG0714, MoxR-like ATPases General function prediction only 167038056 Common - glutamate synthase, alpha subunit domain protein Teth39_1657 145 COG0070 GltB, Glutamate synthase domain 3 Amino acid transport and metabolism 167036957 Common - glycerol-3-phosphate responsive antiterminator, GlpP Teth39_0534 26 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 167038634 Common - Chromate transporter Teth39_2255 115 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 167036645 Common - PHP C-terminal domain protein Teth39_0215 82 COG1796 POL4, DNA polymerase IV (family X) DNA replication, recombination, and repair 167036698 Nonpathogen - hypothetical protein Teth39_0271 1 None None None 167038219 Common - methyl-accepting chemotaxis sensory transducer Teth39_1825 105 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 167038267 Common - peptidase M42 family protein Teth39_1875 86 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 167036950 Common - spore germination protein Teth39_0527 15 None None None 167038616 Nonpathogen - hypothetical protein Teth39_2237 5 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 167037833 Common - NAD/NADP octopine/nopaline dehydrogenase Teth39_1425 26 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 167038445 Common - 6-phosphogluconate dehydrogenase, decarboxylating Teth39_2063 165 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 167037897 Common - protein of unknown function UPF0180 Teth39_1490 10 None None None 167036700 Nonpathogen - hypothetical protein Teth39_0273 1 COG3462 COG3462, Predicted membrane protein Function unknown 167036631 Common - binding-protein-dependent transport systems inner membrane component Teth39_0201 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 167037151 Common - Triose-phosphate isomerase Teth39_0733 222 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 167038641 Common - H+-transporting two-sector ATPase, E subunit Teth39_2262 6 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 167037495 Common - glutamate 5-kinase Teth39_1082 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 167038161 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_1766 100 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167038665 Common - parB-like partition protein Teth39_2286 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 167036746 Common - GTP cyclohydrolase I Teth39_0319 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 167036556 Common - CRISPR-associated helicase Cas3 Teth39_0125 76 COG1203 COG1203, Predicted helicases General function prediction only 167038429 Common - AAA ATPase Teth39_2047 70 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 167037317 Common - cobalamin B12-binding domain protein Teth39_0903 113 COG2185 Sbm, Methylmalonyl-CoA mutase, C-terminal domain/subunit (cobalamin-binding) Lipid metabolism 167037564 Common - thiamine pyrophosphate enzyme domain protein TPP-binding Teth39_1151 111 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 167038550 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit Teth39_2170 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 167037261 Common - transcriptional regulator, CdaR Teth39_0846 31 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 167037527 Common - hypothetical protein Teth39_1114 12 None None None 167038399 Common - efflux transporter, RND family, MFP subunit Teth39_2015 132 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 167038566 Common - binding-protein-dependent transport systems inner membrane component Teth39_2186 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 167038376 Common - protein of unknown function DUF100 Teth39_1992 37 COG1980 COG1980, Archaeal fructose 1,6-bisphosphatase Carbohydrate transport and metabolism 167037475 Common - peptidase U32 Teth39_1062 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 167037847 Common - ribonuclease, Rne/Rng family Teth39_1439 186 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 167038565 Common - binding-protein-dependent transport systems inner membrane component Teth39_2185 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 167036808 Common - ribosomal protein L16 Teth39_0381 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 167037294 Common - ABC transporter related Teth39_0880 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 167037254 Common - small GTP-binding protein Teth39_0839 235 COG1160 COG1160, Predicted GTPases General function prediction only 167037345 Common - Integrase, catalytic region Teth39_0932 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 167038285 Common - cobalamin 5'-phosphate synthase Teth39_1894 139 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 167037092 Common - binding-protein-dependent transport systems inner membrane component Teth39_0671 155 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 167038468 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Teth39_2087 43 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 167038382 Nonpathogen - hypothetical protein Teth39_1998 1 None None None 167038310 Common - protein of unknown function DUF58 Teth39_1921 20 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 167036681 Common - 2,3-diketo-5-methylthio-1-phosphopentane phosphatase Teth39_0254 22 COG4359 COG4359, Uncharacterized conserved protein Function unknown 167036480 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_0049 100 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167037840 Nonpathogen - hypothetical protein Teth39_1432 1 None None None 167037523 Common - Thiamin pyrophosphokinase, catalytic region Teth39_1110 21 COG4825 COG4825, Uncharacterized membrane-anchored protein conserved in bacteria Function unknown 167037286 Common - DivIVA family protein Teth39_0872 42 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 167036448 Common - 3-isopropylmalate dehydratase, small subunit Teth39_0017 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 167036658 Common - carbamoyl-phosphate synthase, large subunit Teth39_0228 234 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 167037805 Common - putative oxygen-independent coproporphyrinogen III oxidase Teth39_1396 209 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 167037540 Common - Polynucleotide adenylyltransferase region Teth39_1127 205 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 167036544 Common - transposase IS116/IS110/IS902 family protein Teth39_0113 58 None None None 167036731 Common - hypothetical protein Teth39_0304 22 None None None 167037597 Common - PHP C-terminal domain protein Teth39_1185 131 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 167036468 Nonpathogen - hypothetical protein Teth39_0037 1 None None None 167037402 Common - protein of unknown function UPF0016 Teth39_0989 74 COG2119 COG2119, Predicted membrane protein Function unknown 167037222 Common - Peptidoglycan glycosyltransferase Teth39_0807 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 167037281 Common - hypothetical protein Teth39_0867 11 None None None 167037370 Common - transcriptional regulator, Crp/Fnr family Teth39_0957 64 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 167037105 Common - Pyruvate kinase., Pyruvate, water dikinase Teth39_0684 236 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 167037955 Common - cell envelope-related transcriptional attenuator Teth39_1552 64 COG1316 LytR, Transcriptional regulator Transcription 167036676 Common - histone family protein DNA-binding protein Teth39_0249 214 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 167036845 Nonpathogen - hypothetical protein Teth39_0420 1 None None None 167037910 Common - Dihydrodipicolinate reductase Teth39_1503 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 167037242 Common - phosphate binding protein Teth39_0827 190 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 167038519 Common - polynucleotide adenylyltransferase/metal dependent phosphohydrolase Teth39_2138 212 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 167038194 Common - protein of unknown function DUF421 Teth39_1799 64 COG2323 COG2323, Predicted membrane protein Function unknown 167038605 Nonpathogen - SAF domain Teth39_2226 1 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 167036667 Common - ApbE family lipoprotein Teth39_0239 140 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 167038486 Common - sugar-phosphate isomerase, RpiB/LacA/LacB family Teth39_2105 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 167038307 Common - transcriptional regulator, LysR family Teth39_1918 193 COG0583 LysR, Transcriptional regulator Transcription 167038315 Common - ABC-3 protein Teth39_1926 196 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 167037977 Common - aldo/keto reductase Teth39_1575 203 COG4989 COG4989, Predicted oxidoreductase General function prediction only 167038032 Common - glycosyl transferase, group 1 Teth39_1632 230 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 167037815 Common - DNA internalization-related competence protein ComEC/Rec2 Teth39_1406 209 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 167038234 Common - metal dependent phosphohydrolase Teth39_1840 119 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 167037108 Common - MATE efflux family protein Teth39_0688 183 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 167037097 Common - alpha amylase, catalytic region Teth39_0676 171 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 167036660 Common - argininosuccinate lyase Teth39_0230 233 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 167036810 Common - ribosomal protein S17 Teth39_0383 227 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 167037906 Common - ABC transporter related Teth39_1499 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 167037110 Common - hypothetical protein Teth39_0690 17 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 167037874 Nonpathogen - hypothetical protein Teth39_1466 1 None None None 167038096 Nonpathogen - hypothetical protein Teth39_1701 2 None None None 167038334 Common - phosphotransferase system PTS, lactose/cellobiose-specific IIA subunit Teth39_1945 31 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 167038510 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG family Teth39_2129 14 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 167036717 Common - hypothetical protein Teth39_0290 3 None None None 167037192 Common - MutS2 family protein Teth39_0775 203 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 167037827 Common - glutamyl-tRNA synthetase Teth39_1419 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 167037082 Common - transcriptional regulator, TetR family Teth39_0661 100 COG1309 AcrR, Transcriptional regulator Transcription 167038064 Common - glutamine synthetase, catalytic region Teth39_1666 151 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 167038115 Common - response regulator receiver protein Teth39_1720 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 167038670 Common - single-stranded nucleic acid binding R3H domain protein Teth39_2291 71 COG1847 Jag, Predicted RNA-binding protein General function prediction only 167036710 Common - diguanylate phosphodiesterase Teth39_0283 163 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 167038011 Common - hypothetical protein Teth39_1609 13 None None None 167038103 Common - phosphoribosylamine--glycine ligase Teth39_1708 232 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 167038027 Common - glucose-1-phosphate thymidylyltransferase Teth39_1627 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 167036850 Common - transposase, mutator type Teth39_0425 81 COG3328 COG3328, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037207 Common - ATP-NAD/AcoX kinase Teth39_0792 15 COG3199 COG3199, Uncharacterized conserved protein Function unknown 167037119 Common - manganese containing catalase Teth39_0699 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 167037363 Common - Radical SAM domain protein Teth39_0950 86 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 167036760 Common - PTS system, fructose subfamily, IIC subunit Teth39_0333 67 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 167037139 Common - small acid-soluble spore protein, alpha/beta type Teth39_0721 7 None None None 167038153 Common - 3H domain protein Teth39_1758 16 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 167038627 Common - Adenylosuccinate synthase Teth39_2248 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 167038260 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_1868 102 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167038492 Common - protein of unknown function DUF1385 Teth39_2111 31 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 167037924 Common - binding-protein-dependent transport systems inner membrane component Teth39_1519 157 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 167037652 Common - flagellar biosynthetic protein FliQ Teth39_1240 98 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 167036894 Common - phospholipid/glycerol acyltransferase Teth39_0470 176 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 167037967 Common - hypothetical protein Teth39_1564 12 None None None 167036923 Common - Integrase, catalytic region Teth39_0499 65 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 167037905 Common - ABC transporter related Teth39_1498 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 167038125 Common - glutamate synthase (NADPH), homotetrameric Teth39_1730 207 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 167037581 Common - hydroxymethylbutenyl pyrophosphate reductase Teth39_1169 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 167037035 Common - extracellular solute-binding protein, family 1 Teth39_0613 131 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 167037547 Common - sodium:dicarboxylate symporter Teth39_1134 165 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 167037517 Common - hemolysin A Teth39_1104 133 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 167036574 Common - protein of unknown function DUF1034 Teth39_0143 103 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 167037661 Common - flagellar operon protein Teth39_1249 16 None None None 167038224 Common - inner-membrane translocator Teth39_1830 138 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 167038503 Common - electron transport complex, RnfABCDGE type, G subunit Teth39_2122 66 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 167038345 Common - leucyl-tRNA synthetase Teth39_1956 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167037233 Common - cell division protein FtsA Teth39_0818 187 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 167036822 Common - methionine aminopeptidase, type I Teth39_0395 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 167038250 Nonpathogen - hypothetical protein Teth39_1857 1 None None None 167037639 Common - protein of unknown function DUF342 Teth39_1227 38 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 167038145 Common - amidohydrolase Teth39_1750 112 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 167037209 Nonpathogen - hypothetical protein Teth39_0794 29 COG1633 COG1633, Uncharacterized conserved protein Function unknown 167038436 Common - Beta-glucosidase Teth39_2054 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 167037215 Common - GTP-binding protein YchF Teth39_0800 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 167037665 Nonpathogen - flagellar export protein FliJ Teth39_1253 3 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 167036433 Common - DNA polymerase III, beta subunit Teth39_0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 167037071 Common - ABC transporter related Teth39_0649 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 167037506 Common - hypothetical protein Teth39_1093 11 None None None 167037228 Common - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase Teth39_0813 213 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 167038398 Common - ABC transporter related Teth39_2014 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 167036829 Common - DNA-directed RNA polymerase, alpha subunit Teth39_0402 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 167037054 Common - PfkB domain protein Teth39_0632 201 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 167036997 Common - biotin--acetyl-CoA-carboxylase ligase Teth39_0575 220 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 167037648 Common - GTP-binding signal recognition particle SRP54, G- domain Teth39_1236 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 167037995 Common - Cupin 2, conserved barrel domain protein Teth39_1593 68 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 167036883 Common - YbbR family protein Teth39_0458 29 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 167037754 Common - oxidoreductase FAD/NAD(P)-binding domain protein Teth39_1342 80 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 167036748 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Teth39_0321 192 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 167037022 Common - carbohydrate kinase, FGGY Teth39_0600 184 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 167037323 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Teth39_0910 13 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 167037428 Common - hypothetical protein Teth39_1015 24 None None None 167038081 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Teth39_1686 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 167038401 Common - DNA-directed DNA polymerase Teth39_2017 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 167037029 Common - extracellular solute-binding protein, family 1 Teth39_0607 83 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 167038133 Common - OmpA/MotB domain protein Teth39_1738 135 COG1360 MotB, Flagellar motor protein Cell motility and secretion 167038214 Common - homocitrate synthase Teth39_1820 224 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 167038452 Common - PTS system fructose subfamily IIA component Teth39_2070 84 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 167036576 Common - D-3-phosphoglycerate dehydrogenase Teth39_0145 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 167036949 Common - LmbE family protein Teth39_0526 22 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 167038574 Common - hypothetical protein Teth39_2194 5 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 167036587 Common - Abortive infection protein Teth39_0156 9 None None None 167038291 Common - cobyric acid synthase CobQ Teth39_1900 153 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 167037250 Nonpathogen - hypothetical protein Teth39_0835 4 None None None 167037536 Common - protein of unknown function DUF1458 Teth39_1123 20 COG3360 COG3360, Uncharacterized conserved protein Function unknown 167038383 Common - protein of unknown function DUF881 Teth39_1999 25 COG3879 COG3879, Uncharacterized protein conserved in bacteria Function unknown 167037603 Common - recA protein Teth39_1191 242 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 167037559 Common - Peptidoglycan-binding LysM Teth39_1146 57 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 167037813 Common - ribosomal protein S20 Teth39_1404 136 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 167037773 Common - DNA repair protein RecO Teth39_1363 84 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 167036942 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Teth39_0519 215 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 167036537 Common - protein of unknown function DUF163 Teth39_0106 158 COG1576 COG1576, Uncharacterized conserved protein Function unknown 167038536 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Teth39_2155 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 167038408 Common - ferrous iron transport protein B Teth39_2024 196 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 167036847 Common - AAA ATPase Teth39_0422 70 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 167036952 Common - Nucleotidyl transferase Teth39_0529 240 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 167037188 Common - phenylalanyl-tRNA synthetase, alpha subunit Teth39_0771 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 167036620 Common - arginyl-tRNA synthetase Teth39_0189 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167036530 Common - AAA ATPase Teth39_0099 105 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 167037318 Common - LAO/AO transport system ATPase Teth39_0904 100 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 167038428 Common - transposase IS116/IS110/IS902 family protein Teth39_2045 66 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037300 Common - Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation)-like protein Teth39_0886 71 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 167037328 Nonpathogen - hypothetical protein Teth39_0915 1 None None None 167036637 Common - methylated-DNA--protein-cysteine methyltransferase Teth39_0207 223 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 167038311 Common - ATPase associated with various cellular activities, AAA_3 Teth39_1922 181 COG0714 COG0714, MoxR-like ATPases General function prediction only 167036550 Common - cysteine desulfurase, SufS subfamily Teth39_0119 241 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 167038274 Common - cobalt ABC transporter, ATPase subunit Teth39_1883 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 167037514 Common - Polyprenyl synthetase Teth39_1101 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 167036918 Common - phosphofructokinase Teth39_0494 148 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 167037623 Common - protein of unknown function DUF448 Teth39_1211 48 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 167037004 Common - transposase, putative Teth39_0582 9 None None None 167037392 Common - L-serine dehydratase, iron-sulfur-dependent, beta subunit Teth39_0979 157 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 167037181 Common - threonyl-tRNA synthetase Teth39_0764 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167037360 Common - ABC-type multidrug transport system ATPase and permease components-like protein Teth39_0947 34 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 167038296 Common - transcriptional modulator of MazE/toxin, MazF Teth39_1905 21 COG2337 MazF, Growth inhibitor Signal transduction mechanisms 167038146 Common - hypothetical protein Teth39_1751 81 COG0398 COG0398, Uncharacterized conserved protein Function unknown 167037539 Common - SpoVA protein Teth39_1126 15 None None None 167037399 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Teth39_0986 239 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 167037757 Common - aspartate carbamoyltransferase Teth39_1345 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 167037619 Common - phosphoesterase, RecJ domain protein Teth39_1207 90 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 167037311 Common - Cystathionine gamma-synthase Teth39_0897 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 167037335 Nonpathogen - hypothetical protein Teth39_0922 4 None None None 167036758 Common - transcriptional antiterminator, BglG Teth39_0331 76 COG3711 BglG, Transcriptional antiterminator Transcription 167037984 Common - prevent-host-death family protein Teth39_1582 20 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 167036777 Nonpathogen - hypothetical protein Teth39_0350 6 None None None 167036618 Common - D-alanine--D-alanine ligase Teth39_0187 229 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 167038034 Common - hypothetical protein Teth39_1634 21 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 167037594 Common - AAA ATPase, central domain protein Teth39_1182 95 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 167036512 Common - hypothetical protein Teth39_0081 10 None None None 167036835 Common - ribosomal protein L13 Teth39_0408 237 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 167036961 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Teth39_0538 206 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 167037419 Common - hypothetical protein Teth39_1006 4 COG0730 COG0730, Predicted permeases General function prediction only 167036598 Common - Aminoacyl-tRNA hydrolase Teth39_0167 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 167038128 Common - Accessory gene regulator B Teth39_1733 8 COG4512 AgrB, Membrane protein putatively involved in post-translational modification of the autoinducing quorum-sensing peptide Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Transcription 167036630 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Teth39_0199 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 167037693 Nonpathogen - hypothetical protein Teth39_1281 2 None None None 167036900 Common - Ku domain protein Teth39_0476 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 167037673 Common - GTP-sensing transcriptional pleiotropic repressor CodY Teth39_1261 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 167036959 Common - glycerol kinase Teth39_0536 180 COG0554 GlpK, Glycerol kinase Energy production and conversion 167036693 Common - hypothetical protein Teth39_0266 6 None None None 167038466 Common - protein of unknown function DUF152 Teth39_2085 180 COG1496 COG1496, Uncharacterized conserved protein Function unknown 167037252 Common - hypothetical protein Teth39_0837 9 None None None 167037764 Common - transposase, IS4 family protein Teth39_1353 8 None None None 167038186 Common - Rubrerythrin Teth39_1791 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 167037403 Common - LmbE family protein Teth39_0990 16 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 167037166 Common - transcriptional regulator, ArsR family Teth39_0749 176 COG0640 ArsR, Predicted transcriptional regulators Transcription 167038176 Common - protein of unknown function DUF180 Teth39_1781 41 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 167036501 Nonpathogen - hypothetical protein Teth39_0070 1 None None None 167037067 Common - Radical SAM domain protein Teth39_0645 175 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 167036977 Common - DNA polymerase, beta domain protein region Teth39_0555 23 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 167037852 Common - methylglyoxal synthase Teth39_1444 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 167036626 Common - ABC-2 type transporter Teth39_0195 43 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 167038352 Nonpathogen - Heterodisulfide reductase subunit A-like protein Teth39_1966 5 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 167036787 Common - preprotein translocase, SecE subunit Teth39_0360 71 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 167036909 Common - carbohydrate kinase, YjeF related protein Teth39_0485 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 167038359 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Teth39_1974 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 167038653 Common - single-strand binding protein Teth39_2274 210 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 167036978 Common - nucleotidyltransferase substrate binding protein, HI0074 family Teth39_0556 33 None None None 167036926 Common - homoserine O-acetyltransferase Teth39_0502 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 167036627 Common - protein of unknown function DUF1568 Teth39_0196 55 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 167038416 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_2033 103 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167038525 Common - methyltransferase small Teth39_2144 117 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 167036875 Common - transposase, putative Teth39_0450 9 None None None 167038207 Common - Hydantoinase/oxoprolinase Teth39_1813 117 COG0145 HyuA, N-methylhydantoinase A/acetone carboxylase, beta subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 167037895 Common - histidine ammonia-lyase Teth39_1488 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 167038360 Common - transcriptional regulator, IclR family Teth39_1975 124 COG1414 IclR, Transcriptional regulator Transcription 167038358 Common - 5-carboxymethyl-2-hydroxymuconate Delta-isomerase Teth39_1973 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 167038003 Common - nucleotidyltransferase substrate binding protein, HI0074 family Teth39_1601 31 None None None 167038459 Common - SAF domain Teth39_2077 37 None None None 167038044 Common - binding-protein-dependent transport systems inner membrane component Teth39_1645 185 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 167037357 Nonpathogen - hypothetical protein Teth39_0944 1 None None None 167038473 Common - protein of unknown function DUF1078 domain protein Teth39_2092 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 167036732 Common - carboxyl transferase Teth39_0305 216 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 167036887 Common - acetate and butyrate kinase Teth39_0462 135 COG3426 COG3426, Butyrate kinase Energy production and conversion 167036907 Common - hypothetical protein Teth39_0483 2 None None None 167037470 Common - beta-lactamase domain protein Teth39_1057 162 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 167036817 Common - ribosomal protein L18 Teth39_0390 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 167038378 Nonpathogen - Dehydrogenase (flavoprotein)-like protein Teth39_1994 8 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 167037641 Common - CheD Teth39_1229 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 167038611 Common - Type IV secretory pathway VirB4 components-like protein Teth39_2232 46 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 167038243 Common - peptidase M42 family protein Teth39_1850 87 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 167037062 Common - Cobyrinic acid a,c-diamide synthase Teth39_0640 39 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 167036751 Common - peptidase S9, prolyl oligopeptidase active site domain protein Teth39_0324 109 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 167038150 Common - preprotein translocase, SecA subunit Teth39_1755 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 167036947 Common - Glycine hydroxymethyltransferase Teth39_0524 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 167038118 Nonpathogen - hypothetical protein Teth39_1723 1 None None None 167037195 Common - two component transcriptional regulator, LuxR family Teth39_0780 222 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 167038542 Common - S23 ribosomal protein Teth39_2161 33 None None None 167038643 Common - H(+)-transporting two-sector ATPase Teth39_2264 48 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 167037279 Common - Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein Teth39_0865 85 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 167037143 Common - VanW family protein Teth39_0725 39 COG2720 COG2720, Uncharacterized vancomycin resistance protein Defense mechanisms 167037204 Common - hypothetical protein Teth39_0789 12 None None None 167037525 Common - glycosyl transferase, family 2 Teth39_1112 174 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 167037520 Common - DNA repair protein RecN Teth39_1107 211 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 167038563 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Teth39_2183 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 167037065 Common - transposase, putative Teth39_0643 7 None None None 167037521 Common - peptidase S55, SpoIVB Teth39_1108 16 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 167038290 Common - cobalamin biosynthesis protein CobD Teth39_1899 150 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 167037608 Nonpathogen - hypothetical protein Teth39_1196 3 None None None 167037288 Common - isoleucyl-tRNA synthetase Teth39_0874 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167038155 Common - metal dependent phosphohydrolase Teth39_1760 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 167037094 Common - hypothetical protein Teth39_0673 35 COG3580 COG3580, Uncharacterized protein conserved in bacteria Function unknown 167037292 Common - Alcohol dehydrogenase GroES domain protein Teth39_0878 188 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 167037366 Common - protein of unknown function DUF969 Teth39_0953 28 COG3819 COG3819, Predicted membrane protein Function unknown 167037494 Common - Xylose isomerase domain protein TIM barrel Teth39_1081 38 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 167037706 Common - protein of unknown function DUF177 Teth39_1294 36 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 167038521 Common - nucleoside recognition domain protein Teth39_2140 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 167037120 Common - hypothetical protein Teth39_0700 9 None None None 167037784 Common - ribosomal protein S21 Teth39_1374 101 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 167037449 Common - aspartyl-tRNA synthetase Teth39_1036 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167038389 Common - ferric uptake regulator, Fur family Teth39_2005 140 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 167036744 Common - transcription elongation factor GreA Teth39_0317 204 COG0782 GreA, Transcription elongation factor Transcription 167037938 Nonpathogen - hypothetical protein Teth39_1533 10 None None None 167038494 Common - ribosomal protein L31 Teth39_2113 181 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 167038581 Common - putative PAS/PAC sensor protein Teth39_2201 150 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 167037179 Common - hypothetical protein Teth39_0762 15 None None None 167036678 Common - SpoIID/LytB domain Teth39_0251 42 COG2385 SpoIID, Sporulation protein and related proteins Cell division and chromosome partitioning 167036991 Common - excinuclease ABC, B subunit Teth39_0569 233 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 167037382 Common - hypothetical protein Teth39_0969 4 None None None 167037791 Nonpathogen - hypothetical protein Teth39_1381 1 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 167038326 Common - putative TIM-barrel protein, nifR3 family Teth39_1937 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 167036455 Common - Riboflavin synthase Teth39_0024 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 167036683 Common - hypothetical protein Teth39_0256 11 None None None 167037960 Common - Phosphomannomutase Teth39_1557 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 167036863 Common - NADH dehydrogenase (quinone) Teth39_0438 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 167037989 Common - hypothetical protein Teth39_1587 18 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 167036709 Common - copper-translocating P-type ATPase Teth39_0282 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 167036998 Common - HPr kinase Teth39_0576 78 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 167036605 Common - protein of unknown function DUF1021 Teth39_0174 18 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 167037270 Common - binding-protein-dependent transport systems inner membrane component Teth39_0856 166 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 167037912 Common - ATP:corrinoid adenosyltransferase BtuR/CobO/CobP Teth39_1505 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 167037416 Common - NUDIX hydrolase Teth39_1003 10 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 167037645 Common - CheB methylesterase Teth39_1233 151 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 167037237 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG family Teth39_0822 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 167038054 Common - thiamine-phosphate pyrophosphorylase Teth39_1655 208 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 167037117 Common - homocysteine S-methyltransferase Teth39_0697 180 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 167037257 Common - hypothetical protein Teth39_0842 15 None None None 167038501 Common - electron transport complex, RnfABCDGE type, A subunit Teth39_2120 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 167037574 Nonpathogen - hypothetical protein Teth39_1162 4 None None None 167038074 Common - sigma54 specific transcriptional regulator, Fis family Teth39_1679 176 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 167037442 Common - D-tyrosyl-tRNA(Tyr) deacylase Teth39_1029 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 167037125 Common - alkylhydroperoxidase like protein, AhpD family Teth39_0706 9 COG2128 COG2128, Uncharacterized conserved protein Function unknown 167037153 Common - Phosphopyruvate hydratase Teth39_0735 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 167038126 Common - oxidoreductase FAD/NAD(P)-binding domain protein Teth39_1731 91 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 167036487 Nonpathogen - hypothetical protein Teth39_0056 5 None None None 167038457 Common - Mandelate racemase/muconate lactonizing enzyme, N-terminal domain protein Teth39_2075 121 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 167036766 Common - transcriptional repressor, CtsR Teth39_0339 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 167037533 Common - anti-sigma-factor antagonist Teth39_1120 50 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 167036702 Common - integral membrane sensor signal transduction histidine kinase Teth39_0275 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 167037831 Common - asparagine synthase (glutamine-hydrolyzing) Teth39_1423 204 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 167037725 Common - serine/threonine protein kinase with PASTA sensor(s) Teth39_1313 163 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 167037358 Common - Radical SAM domain protein Teth39_0945 63 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 167038667 Common - methyltransferase GidB Teth39_2288 200 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 167038138 Common - ribosomal-protein-alanine acetyltransferase Teth39_1743 218 COG0456 RimI, Acetyltransferases General function prediction only 167038265 Common - peptidase M42 family protein Teth39_1873 88 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 167038014 Nonpathogen - DNA polymerase, beta domain protein region Teth39_1612 5 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 167036968 Common - beta-lactamase domain protein Teth39_0545 126 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 167037829 Common - competence protein ComEA helix-hairpin-helix repeat protein Teth39_1421 125 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 167038618 Nonpathogen - hypothetical protein Teth39_2239 1 None None None 167037820 Nonpathogen - hypothetical protein Teth39_1411 1 None None None 167038079 Nonpathogen - hypothetical protein Teth39_1684 1 None None None 167036989 Common - PDZ/DHR/GLGF domain protein Teth39_0567 12 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 167037499 Common - translation elongation factor P Teth39_1086 217 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 167036473 Common - hypothetical protein Teth39_0042 5 None None None 167037502 Common - hypothetical protein Teth39_1089 12 None None None 167037461 Common - transcriptional regulator, BadM/Rrf2 family Teth39_1048 176 COG1959 COG1959, Predicted transcriptional regulator Transcription 167038029 Common - polysaccharide pyruvyl transferase Teth39_1629 20 COG2327 WcaK, Uncharacterized conserved protein Function unknown 167036812 Common - ribosomal protein L24 Teth39_0385 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 167036743 Common - Shikimate/quinate 5-dehydrogenase Teth39_0316 47 COG5322 COG5322, Predicted dehydrogenase General function prediction only 167038113 Common - Xanthine/uracil/vitamin C permease Teth39_1718 137 COG2252 COG2252, Permeases General function prediction only 167038222 Common - cytidine deaminase Teth39_1828 127 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 167037993 Common - putative small multi-drug export Teth39_1591 20 COG2426 COG2426, Predicted membrane protein Function unknown 167037919 Common - binding-protein-dependent transport systems inner membrane component Teth39_1514 170 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 167038157 Common - sigma 54 modulation protein/ribosomal protein S30EA Teth39_1762 161 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 167037190 Common - protein of unknown function DUF710 Teth39_0773 2 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 167037424 Common - hypothetical protein Teth39_1011 4 None None None 167037545 Nonpathogen - hypothetical protein Teth39_1132 4 None None None 167036738 Common - GerA spore germination protein Teth39_0311 15 None None None 167038625 Common - phage integrase family protein Teth39_2246 160 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 167038380 Nonpathogen - hypothetical protein Teth39_1996 3 None None None 167038419 Nonpathogen - hypothetical protein Teth39_2036 5 None None None 167037969 Nonpathogen - hypothetical protein Teth39_1566 4 None None None 167037030 Common - binding-protein-dependent transport systems inner membrane component Teth39_0608 159 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 167036720 Common - ABC transporter related Teth39_0293 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 167037137 Nonpathogen - iron dependent repressor Teth39_0719 4 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 167036446 Common - pyruvate carboxyltransferase Teth39_0015 217 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 167038332 Common - Beta-glucosidase Teth39_1943 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 167036719 Common - hypothetical protein Teth39_0292 21 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 167037650 Common - flagellar biosynthetic protein FlhB Teth39_1238 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 167038062 Common - nitrogen regulatory protein P-II Teth39_1664 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 167037878 Common - extracellular solute-binding protein, family 5 Teth39_1470 209 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 167037080 Nonpathogen - protein of unknown function UPF0236 Teth39_0659 5 None None None 167037037 Common - binding-protein-dependent transport systems inner membrane component Teth39_0615 148 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 167037583 Common - Adenosylmethionine decarboxylase Teth39_1171 74 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 167038123 Common - 8-oxoguanine DNA glycosylase domain protein Teth39_1728 37 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 167037952 Common - ATPase, P-type (transporting), HAD superfamily, subfamily IC Teth39_1549 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 167036819 Common - ribosomal protein L15 Teth39_0392 221 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 167038313 Common - periplasmic solute binding protein Teth39_1924 182 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 167037169 Nonpathogen - hypothetical protein Teth39_0752 1 None None None 167037595 Common - adenylosuccinate lyase Teth39_1183 165 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 167037763 Common - Tetratricopeptide TPR_2 repeat protein Teth39_1351 51 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 167036830 Common - ribosomal protein L17 Teth39_0403 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 167037659 Common - flagellar FlbD family protein Teth39_1247 29 COG1582 FlgEa, Uncharacterized protein, possibly involved in motility Cell motility and secretion 167038168 Nonpathogen - hypothetical protein Teth39_1773 1 None None None 167037365 Common - ABC transporter related Teth39_0952 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 167037793 Common - ABC transporter related Teth39_1383 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 167036839 Common - ABC transporter related Teth39_0412 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 167037376 Common - Radical SAM domain protein Teth39_0963 135 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 167036469 Nonpathogen - hypothetical protein Teth39_0038 1 None None None 167037630 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Teth39_1218 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 167037845 Common - protein of unknown function DUF988 Teth39_1437 19 COG4708 COG4708, Predicted membrane protein Function unknown 167038588 Common - Retron-type reverse transcriptase-like protein Teth39_2209 97 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167038030 Common - glycosyl transferase, family 2 Teth39_1630 189 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 167037908 Common - aspartate-semialdehyde dehydrogenase Teth39_1501 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 167037612 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Teth39_1200 190 COG0756 Dut, dUTPase Nucleotide transport and metabolism 167038317 Common - glycoside hydrolase family 2, sugar binding Teth39_1928 72 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 167037872 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Teth39_1464 25 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 167038481 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Teth39_2100 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 167037325 Common - protein of unknown function DUF81 Teth39_0912 123 COG0730 COG0730, Predicted permeases General function prediction only 167038175 Common - carbon storage regulator, CsrA Teth39_1780 8 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 167037748 Common - S23 ribosomal protein Teth39_1336 33 None None None 167037103 Nonpathogen - hypothetical protein Teth39_0682 10 None None None 167037283 Common - protein of unknown function DUF552 Teth39_0869 55 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 167037338 Common - hypothetical protein Teth39_0925 5 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 167037099 Common - protein of unknown function DUF199 Teth39_0678 55 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 167036595 Common - two component transcriptional regulator, winged helix family Teth39_0164 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 167037860 Common - cell shape determining protein, MreB/Mrl family Teth39_1452 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 167038593 Common - Peptidoglycan-binding domain 1 protein Teth39_2214 28 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 167037164 Common - redox-active disulfide protein 2 Teth39_0747 66 None None None 167037388 Common - 6-phosphogluconate dehydrogenase, decarboxylating Teth39_0975 188 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 167037887 Common - conserved hypothetical protein 1440 Teth39_1479 16 COG4475 COG4475, Uncharacterized protein conserved in bacteria Function unknown 167038093 Common - PTS system, lactose/cellobiose family IIC subunit Teth39_1698 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 167037132 Common - Radical SAM domain protein Teth39_0714 59 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 167038538 Common - SirA family protein Teth39_2157 49 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 167036532 Common - peptidase M23B Teth39_0101 197 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 167037775 Common - GTP-binding protein Era Teth39_1365 239 COG1159 Era, GTPase General function prediction only 167038255 Common - Auxin Efflux Carrier Teth39_1863 162 COG0679 COG0679, Predicted permeases General function prediction only 167036564 Common - CRISPR-associated protein Cas4 Teth39_0133 35 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 167038053 Common - Hydroxyethylthiazole kinase Teth39_1654 85 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 167037285 Common - RNA-binding S4 domain protein Teth39_0871 33 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 167038430 Common - Integrase, catalytic region Teth39_2048 55 None None None 167036984 Common - transcriptional regulator, CdaR Teth39_0562 38 COG3835 CdaR, Sugar diacid utilization regulator Transcription / Signal transduction mechanisms 167037374 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_0961 100 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167037718 Common - Dak phosphatase Teth39_1306 55 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 167036610 Nonpathogen - hypothetical protein Teth39_0179 1 None None None 167037309 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Teth39_0895 189 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 167037867 Common - histidine kinase Teth39_1459 86 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 167036539 Common - tyrosyl-tRNA synthetase Teth39_0108 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167036581 Common - transcriptional regulator, DeoR family Teth39_0150 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 167037302 Common - anthranilate synthase component I Teth39_0888 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 167037675 Common - ATP-dependent protease HslVU (ClpYQ) peptidase subunit-like protein Teth39_1263 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 167038272 Nonpathogen - hypothetical protein Teth39_1881 3 None None None 167037006 Nonpathogen - hypothetical protein Teth39_0584 1 None None None 167036796 Common - ribosomal protein S12 Teth39_0369 245 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 167037625 Common - protein of unknown function DUF150 Teth39_1213 187 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 167036546 Common - chaperonin Cpn10 Teth39_0115 68 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 167037711 Common - hypothetical protein Teth39_1299 33 None None None 167036557 Common - transposase IS116/IS110/IS902 family protein Teth39_0126 99 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 167036779 Common - serine O-acetyltransferase Teth39_0352 225 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 167038475 Common - cell shape determining protein, MreB/Mrl family Teth39_2094 220 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 167037482 Common - type II secretion system protein Teth39_1069 147 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 167036916 Common - Transketolase, central region Teth39_0492 231 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 167037803 Common - GrpE protein Teth39_1394 232 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 167038547 Common - protein of unknown function DUF917 Teth39_2167 30 COG3535 COG3535, Uncharacterized conserved protein Function unknown 167036934 Common - HEPN domain protein Teth39_0511 24 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 167036651 Common - hydrogenase with PAS/PAC sensor Teth39_0221 38 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 167037811 Common - spore protease Teth39_1402 15 None None None 167037454 Common - hypothetical protein Teth39_1041 7 None None None 167037055 Common - transcriptional regulator, LacI family Teth39_0633 128 COG1609 PurR, Transcriptional regulators Transcription 167037298 Common - Cystathionine gamma-lyase Teth39_0884 209 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 167038540 Common - transcriptional regulator, LysR family Teth39_2159 174 COG0583 LysR, Transcriptional regulator Transcription 167037504 Common - hypothetical protein Teth39_1091 15 None None None 167037213 Common - thiamine biosynthesis/tRNA modification protein ThiI Teth39_0798 95 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 167037745 Common - binding-protein-dependent transport systems inner membrane component Teth39_1333 196 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 167036752 Nonpathogen - protein of unknown function DUF1614 Teth39_0325 27 COG4089 COG4089, Predicted membrane protein Function unknown 167037027 Common - ROK family protein Teth39_0605 177 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 167038438 Common - binding-protein-dependent transport systems inner membrane component Teth39_2056 145 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 167036859 Common - monovalent cation/proton antiporter, MnhG/PhaG subunit Teth39_0434 79 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 167038443 Common - TrkA-N domain protein Teth39_2061 137 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 167037172 Nonpathogen - hypothetical protein Teth39_0755 1 None None None 167037605 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Teth39_1193 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 167037752 Common - orotate phosphoribosyltransferase Teth39_1340 112 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 167036441 Common - DNA topoisomerase IV, B subunit Teth39_0010 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 167037435 Common - Carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein Teth39_1022 212 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 167038173 Nonpathogen - LAGLIDADG DNA endonuclease Teth39_1778 2 None None None 167036458 Nonpathogen - hypothetical protein Teth39_0027 1 None None None 167037468 Common - protein of unknown function DUF1292 Teth39_1055 11 COG5023 COG5023, Tubulin Cytoskeleton 167037489 Common - hypothetical protein Teth39_1076 12 None None None 167038284 Common - cobalamin (vitamin B12) biosynthesis CbiX protein Teth39_1893 18 COG2138 COG2138, Uncharacterized conserved protein Function unknown 167038421 Common - Monosaccharide-transporting ATPase Teth39_2038 136 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 167037405 Common - glucosamine-6-phosphate isomerase Teth39_0992 81 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 167037663 Common - flagellar hook-length control protein Teth39_1251 21 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 167038403 Common - putative transcriptional regulator, CopG family Teth39_2019 67 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 167037575 Common - Phosphoglycerate mutase Teth39_1163 197 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 167038216 Common - PTS system, glucose subfamily, IIA subunit Teth39_1822 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 167037020 Common - 6-phosphogluconate dehydrogenase, decarboxylating Teth39_0598 180 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 167037637 Common - ribosomal protein S2 Teth39_1225 245 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 167038180 Common - hypothetical protein Teth39_1785 9 None None None 167037552 Common - Oxidoreductase FAD-binding domain protein Teth39_1139 5 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 167036939 Common - Histidinol dehydrogenase Teth39_0516 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 167038590 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_2211 100 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167037291 Common - transcriptional regulator, GntR family Teth39_0877 123 COG2188 PhnF, Transcriptional regulators Transcription 167036852 Common - transposase IS3/IS911 family protein Teth39_0427 39 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 167037950 Common - Nucleoside-diphosphate kinase Teth39_1547 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 167036695 Common - Integrase, catalytic region Teth39_0268 145 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 167036945 Common - phosphoribosyl-AMP cyclohydrolase Teth39_0522 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 167037008 Common - Resolvase, N-terminal domain Teth39_0586 23 COG2452 COG2452, Predicted site-specific integrase-resolvase DNA replication, recombination, and repair 167036781 Common - ribonuclease III Teth39_0354 39 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 167036928 Common - putative RNA methylase, NOL1/NOP2/sun family Teth39_0504 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 167036791 Common - ribosomal protein L10 Teth39_0364 214 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 167036873 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Teth39_0448 210 COG0546 Gph, Predicted phosphatases General function prediction only 167038188 Common - protein of unknown function DUF1256 Teth39_1793 14 None None None 167037697 Common - beta-ketoacyl synthase Teth39_1285 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 167038042 Common - membrane lipoprotein lipid attachment site Teth39_1643 70 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 167036624 Common - ABC transporter related Teth39_0193 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 167037736 Common - Guanylate kinase Teth39_1324 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 167037854 Common - cell division topological specificity factor MinE Teth39_1446 63 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 167038632 Common - oligoendopeptidase F Teth39_2253 86 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 167037680 Common - tryptophanyl-tRNA synthetase Teth39_1268 238 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 167038061 Common - glutamine amidotransferase class-I Teth39_1662 206 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 167036889 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Teth39_0464 55 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 167036971 Nonpathogen - hypothetical protein Teth39_0549 1 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 167037948 Common - hypothetical protein Teth39_1545 11 None None None 167037343 Common - hypothetical protein Teth39_0930 6 None None None 167036635 Common - NLP/P60 protein Teth39_0205 28 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 167038241 Common - peptidase M42 family protein Teth39_1848 83 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 167038108 Common - phosphoribosylformylglycinamidine synthase II Teth39_1713 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 167037078 Common - isochorismatase hydrolase Teth39_0657 20 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 167037783 Common - GatB/Yqey domain protein Teth39_1373 149 COG1610 COG1610, Uncharacterized conserved protein Function unknown 167037592 Common - phage integrase family protein Teth39_1180 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 167038005 Common - hypothetical protein Teth39_1603 23 COG0622 COG0622, Predicted phosphoesterase General function prediction only 167036525 Common - hypothetical protein Teth39_0094 10 None None None 167038356 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Teth39_1971 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 167038571 Common - S23 ribosomal protein Teth39_2191 33 None None None 167038366 Common - putative sugar-specific permease, SgaT/UlaA Teth39_1982 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 167037610 Common - aspartate kinase Teth39_1198 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 167037723 Common - Ribulose-phosphate 3-epimerase Teth39_1311 217 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 167037512 Common - exodeoxyribonuclease VII, large subunit Teth39_1099 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 167037945 Nonpathogen - hypothetical protein Teth39_1542 1 None None None 167038116 Common - chaperonin GroEL Teth39_1721 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 167037683 Common - GTP-binding protein, HSR1-related Teth39_1271 129 COG1161 COG1161, Predicted GTPases General function prediction only 167038023 Common - Mannose-1-phosphate guanylyltransferase (GDP) Teth39_1623 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 167036963 Nonpathogen - Phosphotransferase system, phosphocarrier protein HPr Teth39_0540 2 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 167036641 Common - ABC transporter related Teth39_0211 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 167036552 Nonpathogen - CRISPR-associated protein Cas6 Teth39_0121 24 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 167036837 Common - S23 ribosomal protein Teth39_0410 33 None None None 167038100 Common - amidohydrolase Teth39_1705 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 167037248 Common - Stage II sporulation P family protein Teth39_0833 13 None None None 167038232 Common - methyl-accepting chemotaxis sensory transducer with Cache sensor Teth39_1838 168 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 167036589 Common - UDP-N-acetylmuramate--alanine ligase Teth39_0158 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 167038528 Common - DNA polymerase III, delta prime subunit Teth39_2147 226 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 167036770 Common - DNA repair protein RadA Teth39_0343 225 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 167038099 Common - polysaccharide biosynthesis protein Teth39_1704 38 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 167036513 Common - hypothetical protein Teth39_0082 2 None None None 167037047 Common - extracellular solute-binding protein, family 1 Teth39_0625 39 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 167038016 Nonpathogen - hypothetical protein Teth39_1614 1 None None None 167038396 Common - 5-carboxymethyl-2-hydroxymuconate Delta-isomerase Teth39_2012 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 167038021 Common - protein of unknown function DUF1648 Teth39_1621 21 COG5658 COG5658, Predicted integral membrane protein Function unknown 167037704 Common - hypothetical protein Teth39_1292 24 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 167037381 Nonpathogen - sigmaK-factor processing regulatory BofA Teth39_0968 1 None None None 167036616 Common - Propeptide, PepSY amd peptidase M4 Teth39_0185 14 None None None 167037060 Nonpathogen - hypothetical protein Teth39_0638 8 None None None 167037890 Common - protein of unknown function DUF86 Teth39_1482 24 COG2445 COG2445, Uncharacterized conserved protein Function unknown 167036528 Common - RNA-directed DNA polymerase (Reverse transcriptase) Teth39_0097 100 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 167036726 Common - tRNA(Ile)-lysidine synthetase Teth39_0299 205 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 167037695 Common - Radical SAM domain protein Teth39_1283 157 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 167038343 Common - branched-chain amino acid transport Teth39_1954 35 COG4392 COG4392, Predicted membrane protein Function unknown 167038450 Common - PTS system mannose/fructose/sorbose family IID component Teth39_2068 36 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 167038572 Nonpathogen - hypothetical protein Teth39_2192 1 COG1633 COG1633, Uncharacterized conserved protein Function unknown 167038068 Nonpathogen - hypothetical protein Teth39_1671 1 None None None 167038393 Common - nuclease SbcCD, D subunit Teth39_2009 121 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 167037880 Common - Lytic transglycosylase, catalytic Teth39_1472 175 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane