Chlamydia trachomatis 434/Bu, complete genome NC_010287 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 166154248 Common trmD tRNA (guanine-N(1)-)-methyltransferase CTL0282 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 166154664 Common uppS undecaprenyl pyrophosphate synthetase CTL0710 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 166154334 Common clpB chaperone-protease ClpB CTL0368 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 166154683 Common - hypothetical protein CTL0729 7 None None None 166154547 Common ptsI phosphoenolpyruvate-protein phosphotransferase CTL0590 194 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 166154836 Pathogen - hypothetical protein CTL0885 2 None None None 166154540 Common xseB exodeoxyribonuclease VII small subunit CTL0583A 20 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 166154556 Common lon ATP-dependent protease La CTL0598 207 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 166154713 Common gidA tRNA uridine 5-carboxymethylase CTL0760 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 166154819 Common - hypothetical protein CTL0868 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 166154080 Common - Zn-dependent hydrolase CTL0107 57 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 166154603 Pathogen - hypothetical protein CTL0648 2 None None None 166154208 Common lcrH type III secretion chaperone CTL0237 17 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 166154526 Common rplL LSU ribosomal protein L12P (L7/L12) CTL0568 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 166154606 Common grpE HSP-70 Cofactor CTL0651 186 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 166154391 Pathogen - hypothetical protein CTL0433 3 None None None 166154089 Common hemE uroporphyrinogen decarboxylase CTL0116 174 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 166154032 Common dppD ABC transport protein, ATPase component CTL0059 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 166154812 Pathogen - histone H1-I CTL0861A 2 None None None 166154018 Common - hypothetical protein CTL0045 7 COG3880 COG3880, Uncharacterized protein with conserved CXXC pairs Function unknown 166154184 Common tilS tRNA(Ile)-lysidine synthase CTL0212 214 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 166154281 Common flhA Flagellar biosynthesis protein (export) CTL0316 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 166154162 Common - tyrosine-specific transport protein CTL0190 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 166154523 Common tal transaldolase CTL0565 187 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 166154230 Common - hypothetical protein CTL0264 42 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 166154461 Common dnaA Chromosomal replication initiation protein CTL0501 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 166154169 Common rmuC DNA recombination protein CTL0197 142 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 166154235 Common cydB cytochrome d ubiquinol oxidase subunit II CTL0269 157 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 166154328 Common - putative DNA glycosylase CTL0362 235 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 166154321 Common acpS holo-[acyl-carrier protein] synthase CTL0355 53 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 166154163 Common - putative membrane transport protein CTL0191 83 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 166154095 Pathogen - hypothetical protein CTL0122 2 None None None 166154503 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase CTL0544 180 COG0756 Dut, dUTPase Nucleotide transport and metabolism 166154214 Pathogen - hypothetical protein CTL0247 2 COG5160 ULP1, Protease, Ulp1 family Posttranslational modification, protein turnover, chaperones 166154314 Common ribF riboflavin kinase CTL0348 211 COG0196 RibF, FAD synthase Coenzyme metabolism 166154258 Pathogen - hypothetical protein CTL0293 3 None None None 166154256 Common - putative protein ligase CTL0290 6 COG4285 COG4285, Uncharacterized conserved protein Function unknown 166154056 Common gpdA glycerol-3-phosphate dehydrogenase (NAD(P)+) CTL0083 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 166154567 Pathogen - hypothetical protein CTL0609 3 None None None 166154135 Common dnaG DNA primase CTL0162 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 166154157 Pathogen - hypothetical protein CTL0185 2 None None None 166154647 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase CTL0693 187 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 166154346 Common rplM LSU ribosomal protein L13P CTL0380 229 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 166154560 Common - ABC transporter, ATP-binding component CTL0602 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 166154630 Common rpmA LSU ribosomal protein L27P CTL0676 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 166154021 Common tsf translation elongation factor TS CTL0048 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 166154827 Common folA dihydrofolate reductase CTL0876 132 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 166154697 Pathogen - hypothetical protein CTL0744 2 None None None 166154304 Pathogen - hypothetical protein CTL0338A 2 None None None 166154176 Common nusB Antitermination protein CTL0204 3 COG0781 NusB, Transcription termination factor Transcription 166154808 Common - putative hydrolase CTL0858 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 166154734 Common rpsQ SSU ribosomal protein S17P CTL0781 239 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 166154408 Common oppA3 oligopeptide transport system binding protein CTL0450 174 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 166154412 Common oppF oligopeptide transport system ATP-binding protein CTL0454 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 166153981 Common recC exodeoxyribonuclease V gamma chain CTL0008 15 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 166154035 Common pgk phosphoglycerate kinase CTL0062 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 166154489 Common nqrB Na(+)-translocating NADH-quinone reductase subunit B CTL0530 73 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 166153977 Common greA Transcription elongation factor CTL0004 193 COG1747 COG1747, Uncharacterized N-terminal domain of the transcription elongation factor GreA Function unknown 166154442 Common - sodium-dependent amino acid transporter CTL0483 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 166154075 Pathogen - hypothetical protein CTL0102 2 None None None 166154276 Common sucB dihydrolipoamide succinyltransferase component (E2) of 2-oxoglutarate dehydrogenase complex CTL0311 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 166154764 Common rsbW sigma regulatory factor-histidine kinase CTL0811 32 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 166154424 Pathogen - candidate inclusion membrane protein CTL0466 2 None None None 166154711 Pathogen - hypothetical protein CTL0758 1 None None None 166153988 Pathogen - hypothetical protein CTL0015 2 None None None 166154152 Pathogen - hypothetical protein CTL0179 1 None None None 166154145 Common rplI LSU ribosomal protein L9 CTL0172 212 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 166154744 Pathogen - hypothetical protein CTL0791 2 None None None 166154463 Common lgt prolipoprotein diacylglyceryl transferase CTL0504 187 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 166154385 Common oppA2 Oligopeptide transport system binding protein CTL0427 145 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 166154747 Common fabZ (3R)-hydroxymyristoyl-[acyl carrier protein] dehydratase CTL0794 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 166154783 Pathogen - hypothetical protein CTL0831 2 None None None 166154587 Pathogen ltuA late transcription unit A protein CTL0631 2 None None None 166154433 Pathogen - candidate inclusion membrane protein CTL0475 1 None None None 166154419 Common leuS leucyl-tRNA synthetase CTL0461 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154573 Common lysC aspartokinase CTL0616 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 166154296 Common dnaN DNA polymerase III, beta chain CTL0331 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 166154353 Common - hypothetical protein CTL0387 11 COG1295 Rbn, Predicted membrane protein Function unknown 166154756 Common mip peptidyl-prolyl cis-trans isomerase CTL0803 136 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 166154838 Pathogen - hypothetical protein CTL0887 3 None None None 166154398 Common tdk thymidylate kinase CTL0440 227 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 166154642 Pathogen - hypothetical protein CTL0688 3 None None None 166154810 Common exbB macromolecule transporter CTL0860 145 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 166154278 Common gcpE 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase CTL0313 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 166154074 Common ribH Riboflavin synthase beta chain (6,7-dimethyl-8-ribityllumazine synthase) CTL0101 226 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 166154594 Pathogen - hypothetical protein CTL0639 2 None None None 166154447 Common acpP acyl carrier protein CTL0488 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 166154457 Common pdhB pyruvate dehydrogenase E1 component beta subunit CTL0498 206 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 166154703 Common glgC glucose-1-phosphate adenylyltransferase CTL0750 167 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 166154189 Pathogen - hypothetical protein CTL0217 3 None None None 166154580 Common aroB 3-dehydroquinate synthase CTL0623 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 166154729 Common rplF LSU ribosomal protein L6P CTL0776 232 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 166154083 Common - preprotein translocase CTL0110 46 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 166154450 Common fabH 3-oxoacyl-[acyl-carrier-protein] synthase III CTL0491 213 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 166154298 Common apbE thiamine biosynthesis lipoprotein CTL0333 120 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 166154303 Pathogen - hypothetical protein CTL0338 2 None None None 166154350 Common - putative ABC-membrane transport protein, inner membrane component CTL0384 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 166154119 Common bioF 8-amino-7-oxononanoate synthase CTL0146 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 166154369 Common mhpA FAD-dependent monooxygenase CTL0403 8 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 166154225 Common gatB aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B CTL0259 209 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 166154774 Common sctJ type III secretion system protein, membrane component CTL0822 68 COG4669 EscJ, Type III secretory pathway, lipoprotein EscJ Intracellular trafficking and secretion 166154797 Common minD Chromosome partitioning ATPase (ParA family) CTL0845 229 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 166154672 Common - ribosomal-protein-alanine acetyltransferase CTL0718 11 COG0456 RimI, Acetyltransferases General function prediction only 166154635 Common - hypothetical protein CTL0681 24 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 166154492 Common nqrE Na(+)-translocating NADH-quinone reductase subunit E CTL0533 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 166154112 Common fabF 3-oxoacyl-[acyl-carrier-protein] synthase CTL0139 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 166154609 Common - hypothetical protein CTL0655 37 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 166154241 Common lepB signal peptidase I CTL0275 105 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 166154362 Common - protein translocase CTL0396 31 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 166154376 Common - phosphatidylcholine-hydrolyzing phospholipase D (PLD) protein CTL0413 27 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 166154382 Common trpA Tryptophan synthase alpha chain CTL0424 210 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 166154206 Pathogen copD2 hypothetical protein CTL0235 2 None None None 166154066 Pathogen - hypothetical protein CTL0093 2 None None None 166154506 Common mrsA phosphoglucomutase CTL0547 240 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 166154677 Common truA tRNA pseudouridine synthase A CTL0723 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 166154004 Common hemA glutamyl-tRNA reductase CTL0031 173 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 166154533 Common infA2 bacterial protein translation initiation factor 1 (IF-1) CTL0575 213 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 166154087 Common hemG protoporphyrinogen oxidase CTL0114 43 COG1232 HemY, Protoporphyrinogen oxidase Coenzyme metabolism 166154736 Common rplP LSU ribosomal protein L16P CTL0783 217 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 166154589 Common - putative nucleotide-binding protein CTL0634 217 COG2262 HflX, GTPases General function prediction only 166154582 Pathogen - hypothetical protein CTL0625 3 None None None 166154165 Common sucC succinyl-CoA synthetase beta chain CTL0193 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 166153992 Pathogen - putative exported lipoprotein CTL0019 2 None None None 166154283 Common tyrS tyrosyl-tRNA synthetase CTL0318 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154064 Common pgmA phosphoglycerate mutase CTL0091 162 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 166154639 Common - hypothetical protein CTL0685 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 166154232 Common - hypothetical protein CTL0266 4 None None None 166153998 Pathogen - hypothetical protein CTL0025 2 None None None 166154323 Pathogen - hypothetical protein CTL0357 2 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 166154237 Pathogen - hypothetical protein CTL0271 3 None None None 166154471 Pathogen - hypothetical protein CTL0512 3 COG5465 COG5465, Uncharacterized conserved protein Function unknown 166154417 Common pfkA_2 pyrophosphate--fructose 6-phosphate 1-phosphotransferase CTL0459 125 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 166154592 Common aroG phospho-2-dehydro-3-deoxyheptonate aldolase CTL0637 179 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 166154108 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase CTL0135 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 166154006 Common - phosphopeptide binding protein (predicted to be a TTSS protein) CTL0033 13 COG1716 COG1716, FOG: FHA domain Signal transduction mechanisms 166154128 Pathogen rpmJ LSU ribosomal protein L36P CTL0154 3 None None None 166154340 Pathogen incA inclusion membrane protein A CTL0374 2 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 166154655 Pathogen crpA cysteine-rich membrane protein CTL0701 2 None None None 166154817 Common ahpC thioredoxin peroxidase CTL0866 229 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 166154260 Pathogen - hypothetical protein CTL0295 1 None None None 166154480 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase CTL0521 215 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 166154198 Common - putative integral membrane protein CTL0226 3 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 166154715 Common ndk nucleoside diphosphate kinase CTL0762 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 166154554 Common rpsU SSU ribosomal protein S21P CTL0596 5 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 166154007 Pathogen - hypothetical protein CTL0034 3 None None None 166154653 Pathogen - hypothetical protein CTL0699 2 None None None 166154121 Pathogen - hypothetical protein CTL0148 2 None None None 166154772 Common lpdA dihydrolipoamide dehydrogenase CTL0820 248 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 166154487 Common - hypothetical protein CTL0528 49 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 166154274 Pathogen - hypothetical protein CTL0309 3 None None None 166154153 Common rpmF LSU ribosomal protein L32 CTL0181 65 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 166154501 Common - PTS-family membrane transport protein IIA component CTL0542 102 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 166154426 Common xasA glutamate/gamma-aminobutyrate antiporter CTL0468 117 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 166154332 Common groES 10 kDa chaperonin GroES CTL0366 213 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 166154521 Pathogen - hypothetical protein CTL0563 2 None None None 166154785 Common gspF general secretion pathway protein F CTL0833 141 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 166154787 Common gspD general secretion pathway protein D CTL0835 136 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 166154143 Common rpsF SSU ribosomal protein S6P CTL0170 106 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 166154820 Common - hypothetical protein CTL0869 234 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 166154762 Pathogen - hypothetical protein CTL0809 3 COG4105 ComL, DNA uptake lipoprotein General function prediction only 166154410 Common oppC oligopeptide transport system membrane permease CTL0452 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 166154406 Pathogen - candidate inclusion membrane protein CTL0448 1 None None None 166154216 Common pmpF polymorphic outer membrane protein CTL0249 14 None None None 166154254 Common recD exodeoxyribonuclease V alpha chain CTL0288 146 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 166154047 Common clpX ATP-dependent Clp protease, ATP-binding component CTL0074 228 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 166154632 Common - putative inner membrane protein CTL0678 71 COG2928 COG2928, Uncharacterized conserved protein Function unknown 166154645 Common glyA serine hydroxymethyltransferase CTL0691 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 166154266 Common - putative aminopeptidase CTL0301 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 166154133 Common uvrC excinuclease ABC subunit C CTL0159 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 166154627 Common - metal transporter, ATP-binding component CTL0673 248 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 166154695 Common - hypothetical protein CTL0742 3 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 166154622 Common lpxB lipid-A-disaccharide synthase CTL0668 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 166154312 Common sctU type III secretion system inner membrane protein CTL0346 129 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 166154562 Common - putative lipoprotein CTL0604 4 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 166154355 Pathogen - hypothetical protein CTL0389 1 None None None 166153983 Pathogen - hypothetical protein CTL0010 3 None None None 166154040 Common trmE tRNA modification GTPase CTL0067 224 COG0486 ThdF, Predicted GTPase General function prediction only 166154640 Common - hypothetical protein CTL0686 32 COG1427 COG1427, Predicted periplasmic solute-binding protein General function prediction only 166154751 Common dnaQ2 DNA polymerase III, epsilon chain CTL0798 195 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 166154149 Pathogen plsB glycerol-3-phosphate acyltransferase CTL0176 4 None None None 166154793 Pathogen copB putative type III secretion system membrane protein CTL0841 2 None None None 166154731 Common rplE LSU ribosomal protein L5P CTL0778 242 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 166154625 Common pmpC polymorphic outer membrane protein CTL0671 7 None None None 166154392 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase CTL0434 145 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 166154159 Common - phosphoglucosamine mutase CTL0187 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 166154187 Common rpsO SSU ribosomal protein S15P CTL0215 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 166154727 Common rpsE SSU ribosomal protein S5P CTL0774 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 166154072 Common ribD Riboflavin biosynthesis protein (diaminohydroxyphosphoribosylaminopyrimidine deaminase) CTL0099 232 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 166154449 Common fabD malonyl-CoA-[acyl-carrier-protein] transacylase CTL0490 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 166154378 Pathogen - hypothetical protein CTL0419 1 None None None 166154308 Common malQ 4-alpha-glucanotransferase CTL0342 120 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 166154701 Common - methyltransferase CTL0748 213 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 166154387 Common dsbG disulfide bond chaperone CTL0429 10 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 166154669 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase CTL0715 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 166154079 Common - SET domain containing protein CTL0106 14 COG2940 COG2940, Proteins containing SET domain General function prediction only 166154749 Common cutE apolipoprotein N-acyltransferase CTL0796 147 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 166154182 Pathogen - putative membrane transport protein CTL0210 3 COG0795 COG0795, Predicted permeases General function prediction only 166154139 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase CTL0166 202 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 166154575 Common dapB dihydrodipicolinate reductase CTL0618 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 166154841 Common rpsD SSU ribosomal protein S4P CTL0890 223 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 166154518 Common atpA V-type ATP synthase alpha chain CTL0560 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 166154831 Pathogen - putative integral membrane protein CTL0880 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 166154538 Common tpiS triosephosphate isomerase CTL0582 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 166154806 Common sdhB succinate dehydrogenase iron-sulfur protein CTL0854 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 166154061 Pathogen fliF flagellar M-Ring Protein CTL0088 2 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 166154455 Pathogen - hypothetical protein CTL0496 2 None None None 166154535 Common - hypothetical protein CTL0577 33 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 166154619 Common lspA lipoprotein signal peptidase CTL0665 46 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 166154243 Common rpmE LSU ribosomal protein L31P CTL0277 148 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 166154724 Common rpsM SSU ribosomal protein S13P CTL0771 241 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 166154541 Pathogen - hypothetical protein CTL0584 2 None None None 166154795 Common - putative integral membrane protein CTL0843 9 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 166154829 Common folX dihydroneopterin aldolase CTL0878 14 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 166154815 Pathogen - putative soluble transglycosylase CTL0864 2 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 166154110 Common - hypothetical protein CTL0137 5 None None None 166154000 Common sfhB ribosomal large subunit pseudouridine synthase D CTL0027 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 166154679 Pathogen - hypothetical protein CTL0725 2 None None None 166154338 Pathogen incF inclusion membrane protein F CTL0372 1 None None None 166154291 Common - ABC transport protein, membrane permease CTL0326 115 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 166154301 Pathogen ltuB late transcription unit B protein CTL0336 2 None None None 166154431 Common - hypothetical protein CTL0473 47 COG1284 COG1284, Uncharacterized conserved protein Function unknown 166154024 Common pbpB penicillin-binding protein CTL0051 176 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 166154224 Common gatA aspartyl-glutamyl-tRNA(Asn-Gln) amidotransferase subunit A CTL0258 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 166154758 Common hisS histidyl-tRNA synthetase CTL0805 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154444 Pathogen incC inclusion membrane protein C CTL0485 1 None None None 166154101 Common nlpD muramidase CTL0128 39 COG1388 LytE, FOG: LysM repeat Cell envelope biogenesis, outer membrane 166154371 Common rpmG LSU ribosomal protein L33P CTL0405 53 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 166154637 Common rsbV anti-sigma F factor antagonist CTL0683 53 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 166154117 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase CTL0144 21 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 166154324 Common - hypothetical protein CTL0358 20 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 166154285 Common lepA GTP-binding protein CTL0320 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 166154500 Pathogen - hypothetical protein CTL0541 2 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 166154694 Common oppA4 oligopeptide transport system, binding protein CTL0741 148 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 166154663 Pathogen - hypothetical protein CTL0709 1 None None None 166154131 Pathogen - putative integral membrane protein CTL0157 1 None None None 166154311 Common lcrD low calcium response protein D (predicted to be part of the TTSS apparatus) CTL0345 127 COG4789 EscV, Type III secretory pathway, component EscV Intracellular trafficking and secretion 166154318 Common nusA N utilization substance protein A CTL0352 216 COG0195 NusA, Transcription elongation factor Transcription 166153982 Common - putative membrane efflux protein CTL0009 139 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 166154039 Common nth endonuclease III CTL0066 237 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 166154268 Common - hypothetical protein CTL0303 5 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 166154612 Common gltT Sodium:dicarboxylate symport protein CTL0658 160 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 166154342 Common araD ribulose-phosphate 3-epimerase CTL0376 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 166154707 Common polA DNA polymerase I CTL0754 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 166154253 Common metG methionyl-tRNA synthetase CTL0287 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166153978 Common aspC Aspartate aminotransferase CTL0005 73 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 166154804 Pathogen - hypothetical protein CTL0852 2 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 166154179 Common rplT LSU ribosomal protein L20P CTL0207 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 166154780 Pathogen - hypothetical protein CTL0828 2 None None None 166154210 Common xerD integrase/recombinase CTL0243 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 166154789 Common pepP proline dipeptidase CTL0837 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 166154051 Common mreB Cell shape determining protein CTL0078 234 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 166154428 Common surE 5'-nucleotidase CTL0470 185 COG0496 SurE, Predicted acid phosphatase General function prediction only 166154331 Common hsp60_1 chaperonin GroEL CTL0365 246 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 166154559 Common xerC DNA recombination protein CTL0601 228 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 166154173 Common trmB tRNA (m(7)G46) methyltransferase CTL0201 158 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 166154651 Common rpsG SSU ribosomal protein S7P CTL0697 243 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 166154038 Pathogen - hypothetical protein CTL0065 2 None None None 166154203 Common - putative membrane transport protein CTL0232 33 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 166154272 Pathogen - hypothetical protein CTL0307 2 None None None 166154516 Common atpD V-type ATP synthase subunit D CTL0558 9 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 166154738 Common rplV LSU ribosomal protein L22P CTL0785 215 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 166154300 Pathogen - putative integral membrane protein CTL0335 3 None None None 166154141 Common rplY LSU ribosomal protein L25 CTL0168 155 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 166154684 Pathogen recO DNA repair protein CTL0730 3 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 166154349 Common adk adenylate kinase CTL0383 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 166154657 Pathogen omcA cysteine-rich outer membrane protein CTL0703 2 None None None 166154507 Pathogen - hypothetical protein CTL0548 2 None None None 166154126 Common rnpA ribonuclease P protein component CTL0153 41 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 166154768 Common - putative methyltransferase CTL0815 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 166154421 Common - hypothetical protein CTL0463 128 COG1678 COG1678, Putative transcriptional regulator Transcription 166154325 Common fabI enoyl-acyl-carrier protein reductase CTL0359 184 COG0623 FabI, Enoyl- acyl-carrier-protein 166154821 Pathogen - hypothetical protein CTL0870 2 None None None 166154430 Common - putative flavoprotein CTL0472 154 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 166154700 Common fliY glutamine-binding protein CTL0747 25 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 166154155 Common pmpD polymorphic outer membrane protein CTL0183 3 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 166154403 Common tgt queuine tRNA-ribosyltransferase CTL0445 230 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 166154629 Common - putative nucleotide-binding protein CTL0675 249 COG0536 Obg, Predicted GTPase General function prediction only 166154520 Common atpE V-type ATP synthase subunit E CTL0562 11 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 166154691 Common - putative DNA methyltransferase CTL0738 20 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 166154439 Pathogen - candidate inclusion membrane protein CTL0480 1 None None None 166154473 Common - hypothetical protein CTL0514 35 COG2107 COG2107, Predicted periplasmic solute-binding protein General function prediction only 166154415 Common pfkA pyrophosphate--fructose 6-phosphate 1-phosphotransferase CTL0457 110 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 166154292 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase CTL0327 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 166154194 Pathogen - hypothetical protein CTL0222 3 None None None 166154204 Common cpa putative exported protease CTL0233 7 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 166154067 Common birA biotin operon repressor CTL0094 126 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 166154816 Pathogen - hypothetical protein CTL0865 3 None None None 166154029 Common sufS cysteine desulfurase CTL0056 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 166154085 Pathogen hctA histone H1--like developmental protein CTL0112 3 None None None 166154009 Pathogen - hypothetical protein CTL0036 3 None None None 166154379 Pathogen - hypothetical protein CTL0419A 1 None None None 166154011 Common sctN ATP synthase (predicted TTSS protein) CTL0038 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 166154091 Common alaS alanyl-tRNA synthetase CTL0118 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154042 Common - hypothetical protein CTL0069 3 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 166154217 Pathogen pmpG polymorphic outer membrane protein CTL0250 2 None None None 166154674 Common - hypothetical protein CTL0720 16 COG5531 COG5531, SWIB-domain-containing proteins implicated in chromatin remodeling Chromatin structure and dynamics 166154365 Pathogen - hypothetical protein CTL0399 2 None None None 166154564 Pathogen secG preprotein translocase CTL0606 3 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 166154222 Pathogen - hypothetical protein CTL0256 2 COG2155 COG2155, Uncharacterized conserved protein Function unknown 166154638 Common - hypothetical protein CTL0684 8 None None None 166154049 Common tig trigger factor (chaperone) CTL0076 125 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 166154620 Common - Sodium/alanine symporter protein CTL0666 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 166154617 Common - transcriptional repressor CTL0663 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 166154245 Common - peptide release factor-glutamine N5-methyltransferase CTL0279 222 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 166154497 Common clpC ATP-dependent Clp protease CTL0538 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 166154058 Common - hypothetical protein CTL0085 3 None None None 166154116 Common cysQ 3'(2'),5'-bisphosphate nucleotidase CTL0143 66 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 166154577 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase CTL0620 225 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 166154770 Common - putative helicase (SWF/SNF family) CTL0818 134 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 166154722 Common rpoA DNA-directed RNA polymerase alpha chain CTL0769 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 166154120 Common priA primosomal protein N' CTL0147 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 166154127 Pathogen rnpA ribonuclease P protein component CTL0153A 2 None None None 166154002 Common gyrA2 DNA gyrase subunit A CTL0029 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 166154010 Pathogen - hypothetical protein CTL0037 2 None None None 166154229 Common rnhC ribonuclease HIII CTL0263 28 COG1039 RnhC, Ribonuclease HIII DNA replication, recombination, and repair 166154306 Common - putative decarboxylase CTL0340 152 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 166154490 Common nqrC Na(+)-translocating NADH-quinone reductase subunit C CTL0531 45 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 166154199 Common - ABC transporter permease CTL0227 167 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 166154590 Common phnP metal-dependent hydrolase CTL0635 81 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 166153984 Common topA DNA topoisomerase I CTL0011 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 166154833 Pathogen - hypothetical protein CTL0882 2 None None None 166154761 Pathogen - hypothetical protein CTL0808 3 None None None 166154446 Common - transcription regulator, crp family CTL0487 46 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 166154389 Pathogen - hypothetical protein CTL0431 2 None None None 166154661 Common recJ single-stranded-DNA-specific exonuclease CTL0707 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 166154454 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase CTL0495 158 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 166154148 Common ptr exported insulinase/protease CTL0175 185 COG1025 Ptr, Secreted/periplasmic Zn-dependent peptidases, insulinase-like Posttranslational modification, protein turnover, chaperones 166154599 Common - hypothetical protein CTL0644 39 COG1872 COG1872, Uncharacterized conserved protein Function unknown 166154753 Pathogen - hypothetical protein CTL0800 3 None None None 166154743 Common rplC LSU ribosomal protein L3P CTL0790 222 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 166154791 Common scc2 type III secretion chaperone (low calcium response protein H) CTL0839 14 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 166154740 Common rplB LSU ribosomal protein L2P CTL0787 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 166154468 Common - hypothetical protein CTL0509 187 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 166154584 Common - Arginine/ornithine antiporter CTL0628 131 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 166154277 Common - hypothetical protein CTL0312 157 COG1496 COG1496, Uncharacterized conserved protein Function unknown 166154766 Common dacC D-alanyl-D-alanine carboxypeptidase CTL0813 150 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 166154423 Common rpiA ribose 5-phosphate isomerase CTL0465 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 166154060 Pathogen - hypothetical protein CTL0087 2 None None None 166154814 Common pal peptidoglycan-associated lipoprotein CTL0863 149 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 166153986 Common - integral membrane protein CTL0013 28 COG0762 COG0762, Predicted integral membrane protein Function unknown 166154397 Common dnaX DNA polymerase III subunit gamma/tau CTL0439 208 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 166154096 Common - hypothetical protein CTL0123 38 COG1409 Icc, Predicted phosphohydrolases General function prediction only 166154270 Pathogen - hypothetical protein CTL0305 2 None None None 166154686 Common - hypothetical protein CTL0733 25 COG1723 COG1723, Uncharacterized conserved protein Function unknown 166154124 Common cysS cysteinyl-tRNA synthetase CTL0151 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154514 Common atpK V-type sodium ATP synthase subunit C CTL0556 17 None None None 166154666 Common cmk cytidylate kinase CTL0712 205 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 166154728 Common rplR LSU ribosomal protein L18P CTL0775 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 166154316 Common rbfA ribosome-binding factor A CTL0350 121 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 166154721 Common rplQ LSU ribosomal protein L17P CTL0768 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 166154053 Pathogen - hypothetical protein CTL0080 2 None None None 166154475 Common - ABC transporter, ATP-binding and membrane components CTL0516 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 166154610 Common - carbohydrate isomerase CTL0656 145 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 166154470 Common - protein phosphatase 2C CTL0511 138 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 166154105 Common - hypothetical protein CTL0132 41 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 166154649 Common rpsJ SSU ribosomal protein S10P CTL0695 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 166154287 Pathogen - hypothetical protein CTL0322 3 None None None 166154825 Common - hypothetical protein CTL0874 35 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 166154219 Pathogen - hypothetical protein CTL0252 1 None None None 166154359 Common - microsomal dipeptidase CTL0393 68 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 166153974 Common hemB delta-aminolevulinic acid dehydratase CTL0001 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 166154212 Common glgB 1,4-alpha-glucan branching enzyme CTL0245 149 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 166154251 Common gmk guanylate kinase CTL0285 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 166154699 Common hemZ ferrochelatase CTL0746 173 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 166154551 Common - hypothetical protein CTL0593 10 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 166154336 Pathogen incD inclusion membrane protein D CTL0370 1 None None None 166154209 Pathogen - hypothetical protein CTL0238 2 None None None 166154026 Common - hypothetical protein CTL0053 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 166154167 Common htrA serine protease CTL0195 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 166154170 Common pssA CDP-diacylglycerol--serine O-phosphatidyltransferase CTL0198 145 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 166154016 Common - Type III secretion structural protein (outer membrane ring) CTL0043 123 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 166154202 Pathogen - hypothetical protein CTL0231B 1 None None None 166154586 Common mdhC malate dehydrogenase CTL0630 81 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 166154705 Common rho transcription termination factor rho CTL0752 206 COG1158 Rho, Transcription termination factor Transcription 166154013 Pathogen - hypothetical protein CTL0040 2 None None None 166154027 Common - ABC transporter ATP-binding protein CTL0054 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 166154466 Common - hypothetical protein CTL0507 86 COG1694 MazG, Predicted pyrophosphatase General function prediction only 166154605 Common - Putative transcriptional regulatory protein CTL0650 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 166154437 Pathogen - candidate inclusion membrane protein CTL0478 1 None None None 166154160 Common glmS glucosamine--fructose-6-phosphate aminotransferase CTL0188 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 166154511 Common pknD Serine/threonine-protein kinase CTL0553 152 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 166154373 Common - lipoprotein release ATP-binding component CTL0407 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 166154261 Common ruvB Holliday junction ATP-dependent DNA helicase CTL0296 218 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 166154823 Common uvrD DNA helicase CTL0872 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 166154196 Common map methionine aminopeptidase CTL0224 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 166154401 Pathogen - hypothetical protein CTL0443 3 None None None 166154327 Common - tRNA pseudouridine synthase A CTL0361 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 166154557 Pathogen - hypothetical protein CTL0599 1 None None None 166153993 Common recD exodeoxyribonuclease V alpha chain CTL0020 125 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 166154505 Common sodM superoxide dismutase CTL0546 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 166154681 Common atoS two component regulator, histidine kinase CTL0727 219 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 166154233 Common - putative integral membrane protein CTL0267 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 166154802 Common eno enolase CTL0850 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 166154177 Common infC bacterial protein translation initiation factor 3 (IF-3) CTL0205 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 166154545 Common dnaX DNA polymerase III subunit gamma/tau CTL0588 246 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 166154247 Common rpsP SSU ribosomal protein S16P CTL0281 203 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 166154798 Pathogen gp6D virulence plasmid protein pGP6-D-related protein CTL0846 3 None None None 166154579 Common aroC chorismate synthase CTL0622 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 166154671 Common - hypothetical protein CTL0717 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 166154494 Pathogen - hypothetical protein CTL0535 3 None None None 166154607 Common dnaK chaperone protein CTL0652 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 166154531 Pathogen secE protein translocase subunit CTL0573 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 166154534 Pathogen - hypothetical protein CTL0576 2 None None None 166154114 Common ppa inorganic pyrophosphatase CTL0141 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 166154693 Common oppB2 oligopeptide transport system membrane permease CTL0740 215 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 166154659 Common gltX glutamyl-tRNA synthetase CTL0705 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 166154435 Pathogen - candidate inclusion membrane protein CTL0477 1 None None None 166154688 Pathogen - hypothetical protein CTL0735 2 None None None 166154172 Common nrdB ribonucleoside-diphosphate reductase beta chain CTL0200 162 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 166154367 Common dnlJ NAD-dependent DNA ligase CTL0401 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 166154315 Common truB tRNA pseudouridine synthase B CTL0349 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 166154566 Common ksgA dimethyladenosine transferase CTL0608 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 166154615 Common - N6-adenine-specific DNA methylase CTL0661 114 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 166154375 Pathogen - phosphatidylcholine-hydrolyzing phospholipase D (PLD) protein CTL0411 3 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 166154527 Common rplJ LSU ribosomal protein L10P CTL0569 127 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 166154452 Common - outer membrane protein (variable surface antigen) CTL0493 154 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 166154357 Common - putative phospholipase-carboxylesterase family protein CTL0391 30 COG0400 COG0400, Predicted esterase General function prediction only 166154093 Common amn AMP nucleosidase CTL0120 84 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 166154597 Common - hypothetical protein CTL0642 16 COG4286 COG4286, Uncharacterized conserved protein related to MYG1 family Function unknown 166154380 Common trpR trp operon repressor CTL0422 21 COG2973 TrpR, Trp operon repressor Transcription 166154755 Common - putatve rRNA methylase (SpoU family) CTL0802 165 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 166154459 Common glgP glycogen phosphorylase CTL0500 137 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 166154043 Common secA preprotein translocase subunit CTL0070 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 166154279 Pathogen - hypothetical protein CTL0314 2 None None None 166154394 Common - putative Holliday junction resolvase CTL0436 123 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 166154289 Common - ABC transport protein, ATP-binding component CTL0324 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 166154294 Common - exported protein CTL0329 26 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 166154078 Common - conserved hyporthetical protein CTL0105 128 COG1881 COG1881, Phospholipid-binding protein General function prediction only 166154484 Pathogen - hypothetical protein CTL0525 2 None None None 166154571 Pathogen - hypothetical protein CTL0614 1 None None None 166154098 Common murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase CTL0125 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 166154186 Common pnp polyribonucleotide nucleotidyltransferase CTL0214 241 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 166154835 Pathogen - hypothetical protein CTL0884 2 None None None 166154846 Pathogen - hypothetical protein CTL0895 3 None None None 166154335 Common - hypothetical protein CTL0369 4 COG2912 COG2912, Uncharacterized conserved protein Function unknown 166154779 Common sctT type III secretion system, membrane protein CTL0827 118 COG4791 EscT, Type III secretory pathway, component EscT Intracellular trafficking and secretion 166154777 Common sctR type III secretion system, membrane protein CTL0825 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 166154482 Pathogen - hypothetical protein CTL0523 3 None None None 166154765 Pathogen - hypothetical protein CTL0812 3 None None None 166154073 Common ribA GTP cyclohydrolase II CTL0100 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 166154759 Common uhpC putative sugar phosphate permease CTL0806 115 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 166153989 Common - hypothetical protein CTL0016 18 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 166154418 Common gseA 3-deoxy-D-manno-octulosonic-acid transferase CTL0460 127 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 166154809 Common dsdD thiol:disulfide interchange protein CTL0859 126 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 166154847 Common - hypothetical protein CTL0897 14 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 166154837 Common - hypothetical protein CTL0886 9 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 166154407 Common gcp O-sialoglycoprotein endopeptidase CTL0449 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 166154195 Common - putative integral membrane protein CTL0223 6 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 166154434 Pathogen - candidate inclusion membrane protein CTL0476 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 166154745 Common fmt methionyl-tRNA formyltransferase CTL0792 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 166154111 Common - hypothetical protein CTL0138 199 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 166154411 Common oppD oligopeptide transport system ATP-binding protein CTL0453 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 166154842 Common - hypothetical protein CTL0891 112 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 166154510 Common hemC porphobilinogen deaminase CTL0551 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 166154448 Common fabG 3-oxoacyl-[acyl-carrier protein] reductase CTL0489 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 166154730 Common rpsH SSU ribosomal protein S8P CTL0777 218 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 166154595 Pathogen - hypothetical protein CTL0640 3 None None None 166154588 Common pgi glucose-6-phosphate isomerase CTL0633 210 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 166154352 Pathogen - hypothetical protein CTL0386 3 None None None 166154704 Pathogen - hypothetical protein CTL0751 2 None None None 166154295 Common recF DNA replication and repair protein CTL0330 167 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 166154456 Common pdhA pyruvate dehydrogenase E1 component alpha subunit CTL0497 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 166154384 Pathogen - hypothetical protein CTL0426 1 None None None 166154213 Pathogen - hypothetical protein CTL0246 2 None None None 166154399 Common gyrA DNA gyrase subunit A CTL0441 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 166154181 Pathogen - hypothetical protein CTL0209 2 None None None 166154361 Common - exported protein CTL0395 35 COG1738 COG1738, Uncharacterized conserved protein Function unknown 166154477 Pathogen - hypothetical protein CTL0518 3 None None None 166154689 Common pheT phenylalanyl-tRNA synthetase beta chain CTL0736 229 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 166154368 Common - putative integral membrane protein CTL0402 6 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 166154600 Common - hypothetical protein CTL0645 6 None None None 166154103 Common murG UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase CTL0130 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 166154118 Common aas 2-acylglycerophosphoethanolamine acyltransferase CTL0145 208 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 166154322 Pathogen - hypothetical protein CTL0356 2 None None None 166154634 Pathogen - hypothetical protein CTL0680 3 None None None 166154297 Common smpB SsrA-binding protein CTL0332 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 166154228 Pathogen - hypothetical protein CTL0262 3 None None None 166154574 Common asd aspartate-semialdehyde dehydrogenase CTL0617 207 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 166154205 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase CTL0234 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 166154796 Common thrS threonyl-tRNA synthetase CTL0844 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154676 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CTL0722 179 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 166154200 Common - sulfate transporter CTL0231 162 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 166154123 Common lysS lysyl-tRNA synthetase CTL0150 240 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 166154469 Common - putative cysteine desulfurase CTL0510 230 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 166154464 Pathogen - putative lipoprotein CTL0505 2 None None None 166154493 Common gcsH glycine cleavage system H protein CTL0534 184 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 166154242 Pathogen - hypothetical protein CTL0276 3 None None None 166154714 Common lplA lipoate-protein ligase A CTL0761 43 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 166154383 Pathogen - hypothetical protein CTL0425 1 None None None 166154003 Common gyrB DNA gyrase subunit B CTL0030 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 166154329 Common - hypothetical protein CTL0363 96 COG0327 COG0327, Uncharacterized conserved protein Function unknown 166154076 Pathogen - putative lipoprotein CTL0103 3 None None None 166154555 Common - O-sialoglycoprotein endopeptidase CTL0597 4 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 166154249 Common rplS LSU ribosomal protein L19P CTL0283 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 166154602 Common - ABC transporter substrate-binding component CTL0647 10 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 166154238 Common - hypothetical protein CTL0272 6 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 166154065 Common - ribosomal large subunit pseudouridine synthase B CTL0092 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 166154097 Common groEL 60 kDa chaperonin GroEL CTL0124 217 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 166154358 Common - hypothetical protein CTL0392 237 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 166154282 Common fliA RNA polymerase sigma factor CTL0317 216 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 166154549 Pathogen - hypothetical protein CTL0592 2 None None None 166154525 Common rpoB DNA-directed RNA polymerase beta chain CTL0567 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 166154025 Common - tetratricopeptide repeat protein CTL0052 138 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 166154164 Common ftsY Cell Division Protein CTL0192 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 166154263 Common - putative glycosyl hydrolase CTL0298 161 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 166153990 Common - hypothetical protein CTL0017 56 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 166154045 Common engA GTP-binding protein CTL0072 223 COG1160 COG1160, Predicted GTPases General function prediction only 166154390 Common - ABC transporter, ATP-binding protein CTL0432 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 166154652 Common rpsL SSU ribosomal protein S12P CTL0698 243 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 166154088 Common hemN coproporphyrinogen oxidase (NAD) CTL0115 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 166154033 Common - hypothetical protein CTL0060 33 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 166154183 Common - putative membrane transport protein CTL0211 4 COG0795 COG0795, Predicted permeases General function prediction only 166154022 Common rpsB SSU ribosomal protein S2 CTL0049 228 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 166154333 Common pepF oligoendopeptidase F CTL0367 87 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 166154643 Common dapF diaminopimelate epimerase CTL0689 197 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 166154733 Common rplN LSU ribosomal protein L14P CTL0780 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 166154654 Common tsp carboxy-terminal processing protease CTL0700 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 166154706 Common - dephospho-CoA kinase CTL0753 200 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 166154696 Pathogen - hypothetical protein CTL0743 2 None None None 166154512 Common valS valyl-tRNA synthetase CTL0554 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154409 Common oppB oligopeptide transport system membrane permease CTL0451 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 166154036 Pathogen - hypothetical protein CTL0063 1 None None None 166154481 Common pbp penicillin-binding protein CTL0522 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 166154631 Common rplU LSU ribosomal protein L21P CTL0677 189 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 166154568 Common - hypothetical protein CTL0610 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 166154646 Pathogen - hypothetical protein CTL0692 2 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 166154472 Common dnaQ DNA polymerase III, epsilon chain CTL0513 183 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 166154255 Common - putative membrane transport/efflux protein CTL0289 26 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 166154190 Pathogen - putative integral membrane protein CTL0218 2 None None None 166154257 Pathogen - hypothetical protein CTL0291 2 None None None 166154015 Common pkn5 putative serine/threonine-protein kinase (TTSS effector protein) CTL0042 134 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 166154158 Pathogen - hypothetical protein CTL0186 2 None None None 166154828 Common folP 2-amino-4-hydroxy-6-hydroxymethyldihydropteridi ne pyrophosphokinase CTL0877 219 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 166154014 Pathogen sctQ Type III secretion component, basal body CTL0041 3 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 166154726 Common rplO LSU ribosomal protein L15P CTL0773 215 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 166154345 Common accC biotin carboxylase CTL0379 223 COG0439 AccC, Biotin carboxylase Lipid metabolism 166154519 Pathogen - hypothetical protein CTL0561 3 None None None 166154313 Common - GTP-binding protein CTL0347 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 166154807 Common sdhA succinate dehydrogenase flavoprotein subunit CTL0855 223 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 166154425 Common dhnA fructose-bisphosphate aldolase CTL0467 54 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 166154413 Common - hypothetical protein CTL0455 6 None None None 166154488 Pathogen - hypothetical protein CTL0529 2 None None None 166154441 Common - putative sodium:dicarboxylate symport protein CTL0482 116 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 166154146 Common ispE 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase CTL0173 156 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 166154275 Common sucA 2-oxoglutarate dehydrogenase E1 component CTL0310 151 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 166154782 Pathogen - hypothetical protein CTL0830 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 166154558 Common - Ribonuclease Z CTL0600 99 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 166154400 Common gyrB2 DNA gyrase subunit B CTL0442 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 166154284 Common gnd 6-phosphogluconate dehydrogenase CTL0319 175 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 166154188 Common - Cytosine deaminase CTL0216 210 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 166154393 Common pyrG CTP synthase CTL0435 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 166154354 Common - putative methyltransferase CTL0388 6 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 166154593 Pathogen - hypothetical protein CTL0638 2 None None None 166154750 Common - acyl-CoA hydrolase CTL0797 134 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 166154624 Common pmpB polymorphic outer membrane protein CTL0670 15 None None None 166154732 Common rplX LSU ribosomal protein L24P CTL0779 169 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 166154608 Common vacB exoribonuclease II CTL0654 192 COG0557 VacB, Exoribonuclease R Transcription 166154641 Common ubiE ubiquinone/menaquinone biosynthesis methyltransferase CTL0687 206 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 166154830 Common rpoD RNA polymerase sigma factor CTL0879 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 166154709 Common - putative nucleotide transport protein CTL0756 6 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 166154839 Common mviN putative virulence protein CTL0888 175 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 166154062 Common - hypothetical protein CTL0089 15 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 166154405 Pathogen - putative integral membrane protein CTL0447 2 None None None 166154718 Common - hypothetical protein CTL0765 3 None None None 166154138 Common glyQ glycyl-tRNA synthetase CTL0165 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 166154576 Pathogen - putative integral membrane protein CTL0619 2 None None None 166154844 Common glmU glucosamine-1-phosphate acetyltransferase CTL0893 206 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 166154792 Pathogen - hypothetical protein CTL0840 2 None None None 166154746 Common lpxA acyl-[acyl-carrier-protein]--UDP-N-acetylglucos amine O-acyltransferase CTL0793 161 COG1043 LpxA, Acyl- acyl carrier protein 166154377 Pathogen - hypothetical protein CTL0417 1 None None None 166154069 Common - cation transporting ATPase CTL0096 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 166154370 Common - hypothetical protein CTL0404 18 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 166154818 Common groEL2 60 kDa chaperonin GroEL2 CTL0867 217 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 166154290 Common - ABC transport protein, membrane permease CTL0325 171 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 166154794 Pathogen copD putative type III secretion system protein CTL0842 2 None None None 166154529 Common rplK LSU ribosomal protein L11P CTL0571 242 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 166154725 Common secY protein translocase subunit CTL0772 242 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 166154244 Common prfA bacterial peptide chain release factor 1 CTL0278 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 166154386 Common dsbB disulfide bond formation protein B CTL0428 21 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 166154542 Common dxs 1-deoxy-D-xylulose 5-phosphate synthase CTL0585 214 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 166154363 Pathogen - hypothetical protein CTL0397 2 None None None 166154499 Pathogen - candidate inclusion membrane protein CTL0540 2 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 166154536 Pathogen - hypothetical protein CTL0580 1 None None None 166154775 Pathogen - hypothetical protein CTL0823 2 None None None 166154636 Common - putative cation efflux protein CTL0682 217 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 166154102 Common ftsW Cell division protein CTL0129 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 166154673 Common prfB bacterial peptide chain release factor 2 CTL0719 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 166154309 Pathogen scc1 type III secretion chaperone CTL0343 3 None None None 166154299 Common folD methylenetetrahydrofolate dehydrogenase (NADP+) CTL0334 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 166154109 Common - hypothetical protein CTL0136 84 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 166154319 Common rpsA SSU ribosomal protein S1P CTL0353 218 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 166154618 Common dksA dnaK suppressor protein CTL0664 144 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 166154678 Common - hydrolase, haloacid dehalogenase-like family CTL0724 51 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 166154702 Common - putative phosphohydrolase CTL0749 15 COG1768 COG1768, Predicted phosphohydrolase General function prediction only 166154023 Pathogen ompA major outer membrane protein CTL0050 2 None None None 166154432 Pathogen - hypothetical protein CTL0474 1 None None None 166153995 Common - ABC transporter ATP-binding protein CTL0022 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 166154302 Pathogen - hypothetical protein CTL0337 1 None None None 166154223 Common gatC glutamyl-tRNA(Gln) amidotransferase subunit C CTL0257 12 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 166154226 Pathogen - hypothetical protein CTL0260 2 None None None 166154100 Common murD UDP-N-acetylmuramoylalanine--D-glutamate ligase CTL0127 208 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 166154081 Common ftsK Cell division protein CTL0108 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 166153991 Common recA recombinase A CTL0018 215 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 166154462 Common oxaA inner membrane protein CTL0503 211 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 166154107 Common rbsV anti-sigma F factor antagonist CTL0134 49 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 166153997 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase CTL0024 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 166154218 Common pmpH polymorphic outer membrane protein CTL0251 4 None None None 166154231 Common htrB lipid A biosynthesis lauroyl acyltransferase CTL0265 38 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 166154265 Common ssb single-strand DNA binding protein CTL0300 8 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 166154650 Common fusA translation elongation factor G CTL0696 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 166154030 Common parB putative chromosome partitioning protein CTL0057 185 COG1475 Spo0J, Predicted transcriptional regulators Transcription 166154031 Common dppF ABC transport protein, ATPase component CTL0058 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 166154524 Common rpoC DNA-directed RNA polymerase beta-prime chain CTL0566 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 166154086 Pathogen - hypothetical protein CTL0113 2 None None None 166154166 Common sucD succinyl-CoA synthetase alpha chain CTL0194 206 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 166154581 Common aroE shikimate 5-dehydrogenase CTL0624 161 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 166154467 Common - putative membrane transport protein CTL0508 214 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 166154716 Common ruvA holliday junction DNA helicase CTL0763 212 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 166154339 Pathogen incG inclusion membrane protein G CTL0373 1 None None None 166154094 Common efp translation elongation factor P CTL0121 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 166154656 Common omcB 60kD cysteine-rich outer membrane protein CTL0702 11 None None None 166154192 Pathogen - hypothetical protein CTL0220 2 None None None 166154479 Common amiA N-acetylmuramoyl-L-alanine amidase CTL0520 182 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 166154553 Common dnaJ heat shock chaperone protein CTL0595 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 166154197 Common - putative integral membrane protein CTL0225 75 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 166154544 Common uvrA excinuclease ABC subunit A CTL0587 242 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 166154005 Pathogen sycE Type III secretion system chaperone CTL0032 2 None None None 166154144 Common rpsR SSU ribosomal protein S18 CTL0171 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 166154063 Common - cysteine desulfurase CTL0090 173 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 166154154 Common plsX Fatty acid/phospholipid synthase CTL0182 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 166154805 Pathogen - hypothetical protein CTL0853 3 None None None 166154420 Common hemL glutamate-1-semialdehyde 2,1-aminomutase CTL0462 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 166154175 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase CTL0203 197 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 166154347 Common rpsI SSU ribosomal protein S9P CTL0381 247 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 166154786 Common gspE general secretion pathway protein E CTL0834 211 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 166154050 Common - putative helicase CTL0077 153 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 166154151 Pathogen - hypothetical protein CTL0178 3 None None None 166154784 Pathogen gspG general secretion pathway protein G CTL0832 3 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 166154800 Common trpS tryptophanyl-tRNA synthetase CTL0848 249 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154427 Common - hypothetical protein CTL0469 113 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 166154504 Common accD acetyl-coenzyme A carboxylase carboxyl transferase subunit beta CTL0545 220 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 166154017 Common aspC aspartate kinase CTL0044 22 COG3869 COG3869, Arginine kinase Amino acid transport and metabolism 166154773 Common lipA lipoic acid synthetase CTL0821 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 166153976 Pathogen - hypothetical protein CTL0003 2 None None None 166154486 Common dnaA2 Chromosomal replication initiation protein CTL0527 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 166154273 Common hemN oxygen-independent coproporphyrinogen-III oxidase CTL0308 206 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 166154517 Common atpB V-type sodium ATP synthase subunit B CTL0559 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 166154020 Common pyrH uridylate kinase CTL0047 234 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 166154071 Common serS seryl-tRNA synthetase CTL0098 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154763 Pathogen - hypothetical protein CTL0810 2 None None None 166154474 Pathogen - hypothetical protein CTL0515 2 None None None 166154735 Pathogen rpmC LSU ribosomal protein L29P CTL0782 2 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 166153980 Common recB exodeoxyribonuclease V beta chain CTL0007 225 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 166154055 Pathogen ompB outer membrane protein B CTL0082 2 None None None 166154623 Common pmpA polymorphic outer membrane protein CTL0669 8 None None None 166154215 Common pmpE polymorphic outer membrane protein CTL0248 5 None None None 166154048 Common clpP ATP-dependent Clp protease proteolytic component CTL0075 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 166154668 Common argS arginyl-tRNA synthetase CTL0714 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154122 Common - protein disulfide isomerase CTL0149 7 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 166154644 Common clpP ATP-dependent Clp protease proteolytic subunit CTL0690 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 166154134 Common mutS DNA mismatch repair protein CTL0160 205 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 166154129 Common rpsN SSU ribosomal protein S14P CTL0155 212 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 166154633 Pathogen - hypothetical protein CTL0679 2 None None None 166154307 Common rpmB LSU ribosomal protein L28P CTL0341 96 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 166154221 Pathogen - hypothetical protein CTL0255 1 None None None 166154364 Pathogen - hypothetical protein CTL0398 2 None None None 166154616 Common ribC riboflavin synthase alpha chain CTL0662 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 166154001 Common - hypothetical protein CTL0028 35 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 166154372 Common - lipoprotein releasing systen, inner membrane component CTL0406 140 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 166154491 Common nqrD Na(+)-translocating NADH-quinone reductase subunit D CTL0532 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 166154710 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase CTL0757 63 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 166154543 Common pykF pyruvate kinase CTL0586 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 166154509 Common radA DNA repair protein CTL0550 208 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 166154246 Common ffh signal recognition particle, subunit FFH/SRP54 CTL0280 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 166154498 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase CTL0539 213 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 166154530 Common nusG transcription antitermination protein CTL0572 215 COG0250 NusG, Transcription antiterminator Transcription 166154057 Common - UDP-N-acetylglucosamine pyrophosphorylase CTL0084 7 COG4284 COG4284, UDP-glucose pyrophosphorylase Carbohydrate transport and metabolism 166154723 Common rpsK SSU ribosomal protein S11P CTL0770 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 166154578 Common aroL shikimate kinase CTL0621 35 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 166153985 Common - putative oxidoreductase CTL0012 205 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 166154799 Pathogen - hypothetical protein CTL0847 2 None None None 166154185 Common ftsH Cell division protein CTL0213 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 166154843 Common ispA dimethylallyltransferase CTL0892 236 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 166154741 Common rplW LSU ribosomal protein L23P CTL0788 76 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 166154443 Pathogen incB inclusion membrane protein B CTL0484 2 None None None 166154271 Pathogen - hypothetical protein CTL0306 2 COG5422 ROM1, RhoGEF, Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases Signal transduction mechanisms 166154330 Pathogen - hypothetical protein CTL0364 2 None None None 166154591 Common artJ arginine transport substrate-binding protein CTL0636 165 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 166154537 Common trpC N-(5'-phosphoribosyl)anthranilate isomerase CTL0581 185 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 166154191 Pathogen - hypothetical protein CTL0219 2 None None None 166154570 Common - putative inner membrane protein CTL0613 96 COG1268 BioY, Uncharacterized conserved protein General function prediction only 166154748 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase CTL0795 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 166154760 Common dnaE DNA polymerase III alpha subunit CTL0807 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 166154147 Common - putative integral membrane protein CTL0174 16 None None None 166154381 Common trpB tryptophan synthase beta chain CTL0423 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 166154044 Pathogen - hypothetical protein CTL0071 2 None None None 166154752 Common - putative nucleotide-binding protein CTL0799 181 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 166154790 Common mutL DNA mismatch repair protein CTL0838 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 166154388 Common - putative integral membrane protein CTL0430 10 None None None 166154343 Common efp translation elongation factor P CTL0377 206 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 166154720 Common gapA glyceraldehyde 3-phosphate dehydrogenase CTL0767 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 166154137 Pathogen - hypothetical protein CTL0164 2 None None None 166154404 Common mgtE magnesium transport protein CTL0446 166 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 166153979 Pathogen - exported protein CTL0006 3 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 166154337 Pathogen incE inclusion membrane protein E CTL0371 1 None None None 166154252 Pathogen - hypothetical protein CTL0286 2 None None None 166154667 Common plsC 1-acyl-sn-glycerol-3-phosphate acyltransferase CTL0713 107 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 166154317 Common infA bacterial protein translation initiation factor 2 (IF-2) CTL0351 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 166154416 Common - hypothetical protein CTL0458 8 COG1073 COG1073, Hydrolases of the alpha/beta superfamily General function prediction only 166154613 Common - Tetraacyldisaccharide-1-P 4'-kinase CTL0659 112 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 166154546 Common - hypothetical protein CTL0589 36 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 166154429 Common ubiA 4-hydroxybenzoate polyprenyltransferase CTL0471 120 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 166154737 Common rpsC SSU ribosomal protein S3P CTL0784 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 166154132 Common - hypothetical protein CTL0158 7 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 166154326 Pathogen - hypothetical protein CTL0360 2 None None None 166154286 Common - ADP,ATP carrier protein CTL0321 18 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 166154341 Pathogen - hypothetical protein CTL0375 1 None None None 166154310 Common copN low calcium response protein E (TTSS effector protein) CTL0344 7 None None None 166154142 Common pth peptidyl-tRNA hydrolase CTL0169 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 166154453 Common ompH Outer membrane protein CTL0494 10 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 166154348 Common - chitinase CTL0382 77 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 166154685 Pathogen - hypothetical protein CTL0731 2 None None None 166154803 Common rbsU sigma regulatory family protein-PP2C phosphatase CTL0851 95 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 166154522 Pathogen - hypothetical protein CTL0564 2 None None None 166154052 Common pckA phosphoenolpyruvate carboxykinase (GTP) CTL0079 59 COG1274 PckA, Phosphoenolpyruvate carboxykinase (GTP) Energy production and conversion 166154460 Pathogen - hypothetical protein CTL0500A 1 None None None 166154422 Common - hypothetical protein CTL0464 58 COG1259 COG1259, Uncharacterized conserved protein Function unknown 166154788 Pathogen - hypothetical protein CTL0836 3 None None None 166154550 Pathogen - hypothetical protein CTL0592A 2 None None None 166154269 Common - hypothetical protein CTL0304 207 COG0313 COG0313, Predicted methyltransferases General function prediction only 166154008 Pathogen - hypothetical protein CTL0035 2 None None None 166154662 Common secF protein translocase (secFG fusion protein) CTL0708a 211 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 166154201 Pathogen - hypothetical protein CTL0231A 1 None None None 166154019 Common rrf ribosome recycling factor CTL0046 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 166154515 Common atpI V-type sodium ATP synthase subunit I CTL0557 26 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 166154174 Common - putative SAM-dependent methyltransferase CTL0202 28 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 166154561 Common - hypothetical protein CTL0603 195 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 166154690 Common - hypothetical protein CTL0737 5 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 166154193 Pathogen - hypothetical protein CTL0221 2 None None None 166154769 Common brnQ branched-chain amino acid transport system carrier protein CTL0817 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 166154832 Common rpsT SSU ribosomal protein S20P CTL0881 106 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 166154717 Common ruvC endodeoxyribonuclease CTL0764 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 166154115 Common ldh leucine dehydrogenase CTL0142 122 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 166154680 Pathogen - hypothetical protein CTL0726 2 None None None 166154156 Common - candidate inclusion membrane protein CTL0184 3 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 166154106 Pathogen - hypothetical protein CTL0133 3 None None None 166154267 Pathogen hct2 Histone-like Protein 2 CTL0302 2 None None None 166154438 Pathogen - candidate inclusion membrane protein CTL0479 1 None None None 166154262 Common - hypothetical protein CTL0297 4 None None None 166154822 Common ung uracil-DNA glycosylase CTL0871 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 166154813 Common tolB outer membrane component of membrane transport system CTL0862 141 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 166154084 Common - rRNA methyltransferase CTL0111 199 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 166154234 Common cydA cytochrome d ubiquinol oxidase subunit I CTL0268 163 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 166154239 Pathogen - hypothetical protein CTL0273 2 None None None 166154626 Common - metal transporter, metal-binding component CTL0672 136 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 166154502 Common ptsN_2 PTS-family membrane transport protein IIA component CTL0543 133 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 166153996 Pathogen - hypothetical protein CTL0023 2 None None None 166153994 Pathogen - hypothetical protein CTL0021 3 None None None 166154180 Common pheS phenylalanyl-tRNA synthetase alpha chain CTL0208 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 166154712 Common dnaB replicative DNA helicase CTL0759 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 166154778 Common sctS type III secretion system, membrane protein CTL0826 74 COG4794 EscS, Type III secretory pathway, component EscS Intracellular trafficking and secretion 166154374 Pathogen - MAC/perforin family protein CTL0408 2 None None None 166154658 Pathogen - putative lipoprotein CTL0704 2 None None None 166154569 Pathogen - candidate inclusion membrane protein CTL0611A 1 None None None 166154621 Common pcnB polyA polymerase CTL0667 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 166154824 Common rpoN RNA polymerase sigma-54 factor CTL0873 143 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 166154495 Common - phospholipase D CTL0536 38 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 166154675 Common - putative metallo-phosphoesterase CTL0721 82 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 166154366 Common pkn1 serine-threonine-protein kinase CTL0400 135 COG1262 COG1262, Uncharacterized conserved protein Function unknown 166154532 Common tufA translation elongation factor Tu CTL0574 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 166154687 Common - hypothetical protein CTL0734 180 COG0759 COG0759, Uncharacterized conserved protein Function unknown 166154220 Common pmpI polymorphic outer membrane protein CTL0254 5 None None None 166154136 Pathogen - hypothetical protein CTL0163 1 None None None 166154565 Common def peptide deformylase CTL0607 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 166154539 Common xseA exodeoxyribonuclease VII large subunit CTL0583 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 166154445 Common - putative membrane transport protein CTL0486 10 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 166154757 Common aspS aspartyl-tRNA synthetase CTL0804 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154496 Common lplA lipoate-protein ligase A CTL0537 23 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 166154305 Common - phosphatidylcholine-hydrolyzing phospholipase D (PLD) protein CTL0339 35 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 166154614 Common - 23S rRNA methyltransferase CTL0660 174 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 166154351 Common - ABC transporter, ATP-binding component CTL0385 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 166154227 Pathogen - hypothetical protein CTL0261 2 None None None 166154171 Common nrdA ribonucleoside-diphosphate reductase alpha chain CTL0199 226 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 166154771 Pathogen - hypothetical protein CTL0819 3 None None None 166154113 Common - hypothetical protein CTL0140 24 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 166153999 Pathogen - hypothetical protein CTL0026 2 None None None 166154077 Common dagA Na(+)-linked D-alanine glycine permease CTL0104 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 166154598 Common - hypothetical protein CTL0643 46 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 166154458 Common pdhC dihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex CTL0499 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 166154046 Common pcnB polyA polymerase CTL0073 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 166154070 Common - putative integral membrane protein CTL0097 3 COG1814 COG1814, Uncharacterized membrane protein Function unknown 166154583 Pathogen - hypothetical protein CTL0626 2 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 166154092 Common tktB transketolase CTL0119 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 166154572 Common dapA dihydrodipicolinate synthase CTL0615 233 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 166154280 Common fer ferredoxin CTL0315 13 COG0633 Fdx, Ferredoxin Energy production and conversion 166154528 Common rplA LSU ribosomal protein L1P CTL0570 236 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 166154834 Pathogen - hypothetical protein CTL0883 2 None None None 166154356 Pathogen - hypothetical protein CTL0390 1 None None None 166154476 Common accA acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha CTL0517 203 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 166154742 Common rplD LSU ribosomal protein L1E CTL0789 217 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 166154845 Common - transcriptional regulatory protein CTL0894 140 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 166154344 Common accB biotin carboxyl carrier protein of acetyl-CoA carboxylase CTL0378 174 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 166154451 Common recR recombination protein CTL0492 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 166154293 Common - putative protease CTL0328 209 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 166154395 Common zwf glucose-6-phosphate 1-dehydrogenase CTL0437 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 166154140 Common glgA glycogen synthase CTL0167 136 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 166154485 Common - hypothetical protein CTL0526 4 None None None 166154099 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transfera se CTL0126 227 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 166154840 Common nfo endonuclease IV CTL0889 97 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 166154012 Pathogen - hypothetical protein CTL0039 3 None None None 166154801 Common uvrB excinuclease ABC subunit B CTL0849 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 166154440 Pathogen - candidate inclusion membrane protein CTL0481 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 166154125 Common - hypothetical protein CTL0152 4 None None None 166154207 Pathogen copB2 putative type III secretion translocator CTL0236 2 None None None 166154320 Common trxB thioredoxin reductase CTL0354 248 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 166154054 Pathogen - hypothetical protein CTL0081 2 None None None 166154259 Common dcd deoxycytidine triphosphate deaminase CTL0294 148 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 166154508 Common rnc ribonuclease III CTL0549 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 166154178 Common rpmI LSU ribosomal protein L35P CTL0206 25 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 166154478 Common ihfA integration host factor alpha-subunit CTL0519 163 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 166154767 Pathogen - hypothetical protein CTL0814 2 None None None 166154660 Pathogen euo conserved hypothetical protein (Early upstream open reading frame) CTL0706 3 None None None 166154552 Common - 2-oxoisovalerate dehydrogenase alpha subunit CTL0594 187 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 166154150 Common cafE ribonuclease E CTL0177 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 166154811 Common - macromolecule transport protein CTL0861 27 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 166153987 Pathogen - hypothetical protein CTL0014 2 None None None 166154483 Common mraW S-adenosyl-L-methionine-dependent methyltransferase CTL0524 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 166154665 Common cdsA phosphatidate cytidylyltransferase CTL0711 173 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 166154698 Pathogen - hypothetical protein CTL0745 3 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 166154585 Common - putative oxidoreductase CTL0629 12 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 166154628 Common - metal transporter, membrane permease component CTL0674 183 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 166154781 Pathogen - hypothetical protein CTL0829 2 None None None 166154250 Common rnhB ribonuclease HII CTL0284 227 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 166154059 Common fliI flagellum-specific ATP synthase CTL0086 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 166154414 Common - sodium:sulfate symporter CTL0456 93 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 166154648 Common - Putative oxidoreductase CTL0694 86 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 166154037 Pathogen - hypothetical protein CTL0064 2 None None None 166154739 Common rpsS SSU ribosomal protein S19P CTL0786 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 166154754 Common trxA thioredoxin CTL0801 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 166154826 Common - hypothetical protein CTL0875 34 COG1478 COG1478, Uncharacterized conserved protein Function unknown 166154611 Common sucB lipoamide acyltransferase component (E2) of branched-chain alpha-keto acid dehydrogenase complex CTL0657 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 166154211 Pathogen - hypothetical protein CTL0244 3 None None None 166153975 Common nqrA Na(+)-translocating NADH-quinone reductase subunit A CTL0002 39 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 166154130 Pathogen - hypothetical protein CTL0156 2 None None None 166154288 Common - ABC transport protein, solute binding component CTL0323 140 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 166154034 Common - low-affinity inorganic phosphate transporter CTL0061 171 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 166154264 Pathogen - putative type III secretion system chaperone CTL0299 3 None None None 166154240 Common ileS isoleucyl-tRNA synthetase, mupirocin resistant CTL0274 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154436 Pathogen - candidate inclusion membrane protein CTL0477A 1 None None None 166154161 Common tyrP tyrosine-specific transport protein CTL0189 31 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 166154236 Common - hypothetical protein CTL0270 199 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 166154604 Common proS prolyl-tRNA synthetase CTL0649 231 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 166154041 Common psdD phosphatidylserine decarboxylase CTL0068 97 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 166154360 Common oppA oligopeptide transport system binding protein CTL0394 113 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 166154596 Common - hypothetical protein CTL0641 184 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 166154068 Common - cell cycle protein CTL0095 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 166154082 Common dmpP Na(+)-translocating NADH-quinone reductase subunit F CTL0109 125 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 166154402 Pathogen - candidate inclusion membrane protein CTL0444 1 None None None 166154692 Common oppC2 oligonucleotide transport system permease CTL0739 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 166154465 Common - inner membrane protein CTL0506 23 None None None 166154396 Common devB 6-phosphogluconolactonase CTL0438 107 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 166154028 Common - hypothetical protein CTL0055 154 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 166154563 Pathogen - hypothetical protein CTL0605 3 None None None 166154090 Common mfd transcription-repair coupling factor CTL0117 219 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 166154601 Common dapL DAP (diaminopimelic acid) aminotransferase CTL0646 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 166154670 Common tarp Translocated actin-recruiting phosphoprotein CTL0716 19 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 166154719 Pathogen - hypothetical protein CTL0766 3 None None None 166154168 Common - metalloprotease-insulinase CTL0196 44 COG1026 COG1026, Predicted Zn-dependent peptidases, insulinase-like General function prediction only 166154513 Pathogen - hypothetical protein CTL0555 2 None None None 166154682 Common atoC two component system response regulator CTL0728 208 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 166154548 Common ptsH phosphocarrier protein HPr CTL0591 105 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 166154104 Common murC UDP-N-acetylmuramate--alanine ligase CTL0131 222 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 166154776 Common sctL type III secretion system protein CTL0824 51 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 166154708 Common sohB exported protease IV CTL0755 168 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion