Methylobacterium extorquens PA1, complete genome NC_010172 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 163850571 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Mext_1139 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163854106 Nonpathogen - hypothetical protein Mext_4710 1 None None None 163854152 Common - Fusaric acid resistance protein conserved region Mext_4756 42 COG1289 COG1289, Predicted membrane protein Function unknown 163853810 Common - ribosomal protein L21 Mext_4414 196 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 163851464 Common - protein of unknown function DUF820 Mext_2040 30 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 163851924 Common - RNA polymerase sigma-54 factor, RpoN Mext_2501 143 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 163852917 Common - UspA domain protein Mext_3504 37 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 163852618 Nonpathogen - hypothetical protein Mext_3203 1 None None None 163849852 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Mext_0402 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 163850039 Nonpathogen - putative exported protein of unknown function Mext_0597 2 None None None 163850681 Common - metal-dependent phosphohydrolase HD sub domain Mext_1251 123 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 163852759 Common - DSBA oxidoreductase Mext_3344 47 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 163853100 Common - hypothetical protein Mext_3696 24 None None None 163851687 Common - Phosphoribosyl-AMP cyclohydrolase Mext_2264 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 163851712 Common - protein of unknown function DUF163 Mext_2289 157 COG1576 COG1576, Uncharacterized conserved protein Function unknown 163853639 Common - addiction module killer protein Mext_4242 34 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 163850837 Common - cytochrome c-type biogenesis protein CcmI Mext_1408 56 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 163852840 Common - AMP-dependent synthetase and ligase Mext_3426 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163850617 Nonpathogen - hypothetical protein Mext_1187 1 None None None 163853451 Common - protein of unknown function DUF937 Mext_4053 33 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 163850708 Common - binding-protein-dependent transport systems inner membrane component Mext_1279 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 163853201 Common - efflux transporter, RND family, MFP subunit Mext_3799 104 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163853028 Common - PAS sensor protein Mext_3622 208 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163853878 Common - aminoglycoside phosphotransferase Mext_4482 69 COG3001 COG3001, Uncharacterized protein conserved in bacteria Function unknown 163851598 Common - ribosomal protein L17 Mext_2175 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 163851156 Common - molybdopterin dehydrogenase FAD-binding Mext_1729 48 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 163849599 Nonpathogen - hypothetical protein Mext_0144 11 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163851407 Nonpathogen - hypothetical protein Mext_1980 1 None None None 163851824 Nonpathogen - hypothetical protein Mext_2401 3 None None None 163853376 Common - FeS assembly protein SufB Mext_3977 184 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 163853346 Common - Cold-shock protein DNA-binding Mext_3947 178 COG1278 CspC, Cold shock proteins Transcription 163852027 Common - flagellar basal-body rod protein FlgC Mext_2607 124 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 163850913 Common - putative transcriptional regulator, CopG family Mext_1484 15 None None None 163852013 Common - hydroxymethylbutenyl pyrophosphate reductase Mext_2593 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 163853518 Nonpathogen - putative iron uptake protein Mext_4120 1 None None None 163852607 Common - SsrA-binding protein Mext_3192 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 163850016 Common - protein of unknown function DUF540 Mext_0573 27 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 163849695 Common - Phosphoglycerate mutase Mext_0242 32 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 163853387 Nonpathogen - hypothetical protein Mext_3988 3 None None None 163849640 Common - potassium efflux system protein Mext_0186 165 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 163852399 Common - peptide chain release factor 2 Mext_2982 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 163851654 Common - hypothetical protein Mext_2231 5 None None None 163852373 Common - YiaAB two helix domain protein Mext_2956 15 COG4298 COG4298, Uncharacterized protein conserved in bacteria Function unknown 163850898 Common - ATP synthase F1, delta subunit Mext_1469 173 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 163849796 Common - binding-protein-dependent transport systems inner membrane component Mext_0344 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 163851519 Nonpathogen - hypothetical protein Mext_2095 3 None None None 163852695 Common - PAS sensor protein Mext_3280 138 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163852766 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Mext_3351 211 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 163853855 Nonpathogen - hypothetical protein Mext_4459 1 None None None 163853752 Common - 3-isopropylmalate dehydratase, large subunit Mext_4355 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 163852665 Common - phosphoesterase PA-phosphatase related Mext_3250 39 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 163851394 Common - Homoserine dehydrogenase Mext_1967 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 163853370 Common - hypothetical protein Mext_3971 11 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 163851451 Common - glycogen/starch synthase, ADP-glucose type Mext_2025 162 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 163850111 Nonpathogen - protein of unknown function DUF1449 Mext_0669 5 None None None 163852322 Common - response regulator receiver Mext_2905 100 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 163852064 Common - quinolinate synthetase complex, A subunit Mext_2644 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 163851036 Nonpathogen - hypothetical protein Mext_1609 1 None None None 163851640 Common - CBS domain containing protein Mext_2217 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 163851609 Common - ribosomal protein L6 Mext_2186 237 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 163851759 Common - WD-40 repeat protein Mext_2336 51 COG2319 COG2319, FOG: WD40 repeat General function prediction only 163852731 Common - lipolytic protein G-D-S-L family Mext_3316 70 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 163851342 Common - putative secreted protein Mext_1915 19 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 163854264 Common - asparagine synthase family amidotransferase Mext_4868 152 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 163850569 Nonpathogen - hypothetical protein Mext_1137 7 None None None 163851763 Common - protein of unknown function DUF1025 Mext_2340 42 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 163853245 Common - oxidoreductase molybdopterin binding Mext_3845 130 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 163854253 Nonpathogen - hypothetical protein Mext_4857 1 None None None 163850763 Common - FMN-binding domain protein Mext_1334 47 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 163852682 Common - glutamate synthase, NADH/NADPH, small subunit Mext_3267 200 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 163851536 Common - ATP-binding region ATPase domain protein Mext_2113 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163852365 Common - cell division protein FtsA Mext_2948 177 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 163850539 Nonpathogen - hypothetical protein Mext_1107 2 None None None 163852031 Common - transglutaminase domain protein Mext_2611 74 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 163850455 Nonpathogen - hypothetical protein Mext_1022 1 None None None 163852952 Nonpathogen - hypothetical protein Mext_3541 1 None None None 163852107 Common - putative membrane protein of unknown function Mext_2688 58 COG0392 COG0392, Predicted integral membrane protein Function unknown 163849978 Common - hypothetical protein Mext_0535 26 None None None 163849738 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Mext_0286 61 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 163854112 Common - phosphate ABC transporter, ATPase subunit Mext_4716 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 163849719 Nonpathogen - hypothetical protein Mext_0267 1 None None None 163849652 Nonpathogen - glycosyl transferase group 1 Mext_0198 1 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163853993 Common - acyl-CoA dehydrogenase domain protein Mext_4597 101 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 163853529 Common - glycosyl transferase, WecB/TagA/CpsF family Mext_4132 111 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 163853550 Common - hypothetical protein Mext_4153 25 None None None 163852458 Common - flagellar P-ring protein Mext_3041 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 163851982 Common - phasin Mext_2560 9 COG5490 COG5490, Uncharacterized conserved protein Function unknown 163852337 Common - 3-oxoacid CoA-transferase, B subunit Mext_2920 92 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 163849504 Nonpathogen - hypothetical protein Mext_0048 1 COG4371 COG4371, Predicted membrane protein Function unknown 163849483 Common - malonate decarboxylase, gamma subunit Mext_0027 28 None None None 163849647 Common - hypothetical protein Mext_0193 14 COG3801 COG3801, Uncharacterized protein conserved in bacteria Function unknown 163852069 Common - protein of unknown function DUF971 Mext_2649 52 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 163851744 Common - threonyl-tRNA synthetase Mext_2321 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163849941 Nonpathogen - hypothetical protein Mext_0497 1 None None None 163853254 Common - isochorismatase hydrolase Mext_3854 118 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 163850127 Common - flagellar FlbT family protein Mext_0687 19 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 163851558 Common - hypothetical protein Mext_2135 4 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 163849926 Common - Integrase catalytic region Mext_0481 85 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 163850404 Nonpathogen - hypothetical protein Mext_0971 1 None None None 163854156 Common - Tol-Pal system beta propeller repeat protein TolB Mext_4760 159 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 163851041 Nonpathogen - hypothetical protein Mext_1614 1 None None None 163852228 Common - TPR repeat-containing protein Mext_2809 123 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 163853535 Nonpathogen - hypothetical protein Mext_4138 2 None None None 163853444 Common - formamidopyrimidine-DNA glycosylase Mext_4046 178 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 163852386 Common - tetraacyldisaccharide 4'-kinase Mext_2969 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 163849629 Common - integrase family protein Mext_0175 11 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163853192 Common - transposase IS4 family protein Mext_3790 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 163853434 Common - response regulator receiver Mext_4036 130 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 163853648 Nonpathogen - hypothetical protein Mext_4251 1 None None None 163852138 Nonpathogen - transcription activator effector binding Mext_2719 6 COG4978 COG4978, Transcriptional regulator, effector-binding domain/component Transcription / Signal transduction mechanisms 163851657 Common - adenylylsulfate reductase, thioredoxin dependent Mext_2234 154 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 163850088 Common - protein of unknown function DUF6 transmembrane Mext_0646 55 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 163850515 Common - NADH (or F420H2) dehydrogenase, subunit C Mext_1083 176 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 163852902 Common - Carbohydrate-selective porin OprB Mext_3489 9 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 163852611 Common - RelA/SpoT family protein Mext_3196 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 163852052 Nonpathogen - hypothetical protein Mext_2632 1 None None None 163852707 Nonpathogen - hypothetical protein Mext_3292 2 None None None 163851667 Common - Alcohol dehydrogenase zinc-binding domain protein Mext_2244 112 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 163851637 Common - transglutaminase domain protein Mext_2214 93 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 163851865 Nonpathogen - hypothetical protein Mext_2442 1 COG4570 Rus, Holliday junction resolvase DNA replication, recombination, and repair 163851456 Common - diguanylate cyclase Mext_2032 183 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163851568 Common - LysR substrate-binding Mext_2145 134 COG0583 LysR, Transcriptional regulator Transcription 163851739 Common - hypothetical protein Mext_2316 69 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 163852141 Common - pseudouridine synthase Mext_2722 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 163853295 Nonpathogen - hypothetical protein Mext_3896 10 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163851930 Common - Dihydrodipicolinate reductase Mext_2507 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 163850534 Common - ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent Mext_1102 169 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 163853818 Nonpathogen - hypothetical protein Mext_4422 2 None None None 163852645 Common - cobalt chelatase, pCobS small subunit Mext_3230 68 COG0714 COG0714, MoxR-like ATPases General function prediction only 163850189 Nonpathogen - hypothetical protein Mext_0749 14 None None None 163853606 Common - integrase domain protein SAM domain protein Mext_4209 24 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163852608 Common - protein of unknown function DUF88 Mext_3193 63 COG1432 COG1432, Uncharacterized conserved protein Function unknown 163851777 Common - protein of unknown function DUF1465 Mext_2354 18 COG5317 COG5317, Uncharacterized protein conserved in bacteria Function unknown 163849615 Nonpathogen - hypothetical protein Mext_0161 1 COG5373 COG5373, Predicted membrane protein Function unknown 163851832 Common - hypothetical protein Mext_2409 162 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 163852195 Common - protein of unknown function DUF892 Mext_2776 25 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 163851835 Common - Radical SAM domain protein Mext_2412 47 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 163853275 Common - ribose-phosphate pyrophosphokinase Mext_3875 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 163851553 Common - protein of unknown function DUF167 Mext_2130 20 COG1872 COG1872, Uncharacterized conserved protein Function unknown 163853322 Common - metal dependent phophohydrolase Mext_3923 121 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 163853126 Common - hypothetical protein Mext_3724 48 COG3665 COG3665, Uncharacterized conserved protein Function unknown 163852098 Common - Inositol-3-phosphate synthase Mext_2679 60 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 163849770 Common - hypothetical protein Mext_0318 7 None None None 163851097 Common - Methyltransferase type 11 Mext_1670 174 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163851300 Common - DnaB domain protein helicase domain protein Mext_1873 215 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 163852724 Common - oxidoreductase molybdopterin binding Mext_3309 117 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 163853844 Common - histidine triad (HIT) protein Mext_4448 65 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 163850974 Common - uracil phosphoribosyltransferase Mext_1547 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 163850622 Common - 67 kDa myosin-cross-reactive antigen family protein Mext_1192 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 163849887 Common - PAS sensor protein Mext_0437 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163852174 Nonpathogen - hypothetical protein Mext_2755 1 None None None 163850848 Common - phage cell wall peptidase, NlpC/P60 family Mext_1419 17 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 163853557 Nonpathogen - hypothetical protein Mext_4160 1 None None None 163850051 Common - major facilitator superfamily MFS_1 Mext_0609 13 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 163851850 Common - terminase large subunit Mext_2427 29 COG1783 XtmB, Phage terminase large subunit General function prediction only 163853848 Common - ATP-binding region ATPase domain protein Mext_4452 83 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 163849495 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Mext_0039 141 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 163852922 Common - metal-dependent phosphohydrolase HD sub domain Mext_3509 175 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 163853945 Nonpathogen - hypothetical protein Mext_4549 1 None None None 163851061 Common - tRNA pseudouridine synthase A Mext_1634 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 163853124 Common - urea carboxylase Mext_3722 227 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 163852222 Common - Beta-ketoacyl-acyl-carrier-protein synthase I Mext_2803 204 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 163852488 Common - queuine tRNA-ribosyltransferase Mext_3071 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 163850256 Common - flagellar protein export ATPase FliI Mext_0823 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 163852968 Common - NAD-dependent epimerase/dehydratase Mext_3560 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163849914 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Mext_0465 18 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 163851999 Common - RNA polymerase sigma factor, sigma-70 family Mext_2578 158 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 163853725 Common - Endonuclease/exonuclease/phosphatase Mext_4328 59 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 163849937 Nonpathogen - hypothetical protein Mext_0493 6 COG5490 COG5490, Uncharacterized conserved protein Function unknown 163851969 Common - metallophosphoesterase Mext_2547 12 COG1409 Icc, Predicted phosphohydrolases General function prediction only 163852358 Common - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase Mext_2941 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 163851660 Common - sulfite reductase (NADPH) hemoprotein, beta-component Mext_2237 149 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 163853659 Common - protein-L-isoaspartate O-methyltransferase Mext_4262 158 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 163854143 Common - CreA family protein Mext_4747 57 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 163850441 Common - hypothetical protein Mext_1008 30 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 163852767 Common - protein of unknown function DUF971 Mext_3352 48 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 163850955 Common - hypothetical protein Mext_1528 23 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 163850144 Common - major facilitator superfamily MFS_1 Mext_0704 64 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163850510 Common - NADH dehydrogenase (quinone) Mext_1078 189 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 163851090 Common - type I secretion system ATPase Mext_1663 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 163850904 Common - chromate transporter, chromate ion transporter (CHR) family Mext_1475 106 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 163853184 Common - protein of unknown function YGGT Mext_3782 30 COG0762 COG0762, Predicted integral membrane protein Function unknown 163852828 Common - hypothetical protein Mext_3414 31 COG4307 COG4307, Uncharacterized protein conserved in bacteria Function unknown 163853881 Common - ABC transporter domain protein Mext_4485 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 163850090 Common - Rieske (2Fe-2S) domain protein Mext_0648 93 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 163853053 Common - Methyltransferase type 11 Mext_3647 24 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 163851766 Nonpathogen - hypothetical protein Mext_2343 1 None None None 163850568 Common - acetate and butyrate kinase Mext_1136 159 COG0282 ackA, Acetate kinase Energy production and conversion 163852933 Common - helix-turn-helix domain protein Mext_3522 41 COG1396 HipB, Predicted transcriptional regulators Transcription 163854061 Nonpathogen - hypothetical protein Mext_4665 1 None None None 163851863 Nonpathogen - hypothetical protein Mext_2440 1 None None None 163849815 Common - conserved hypothetical membrane spanning protein Mext_0365 4 None None None 163849705 Common - integrase family protein Mext_0253 103 COG0582 XerC, Integrase DNA replication, recombination, and repair 163852330 Common - AlkA domain protein Mext_2913 90 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 163853137 Common - helix-turn-helix- domain containing protein AraC type Mext_3735 142 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 163850508 Common - NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Mext_1076 94 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 163854180 Common - Mg2 transporter protein CorA family protein Mext_4784 125 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 163849478 Common - short-chain dehydrogenase/reductase SDR Mext_0021 229 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 163853309 Common - MiaB-like tRNA modifying enzyme YliG Mext_3910 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 163852390 Common - response regulator receiver Mext_2973 197 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163853146 Common - Electron transfer flavoprotein alpha subunit Mext_3744 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 163849659 Common - hypothetical protein Mext_0205 10 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 163850486 Common - translation initiation factor IF-1 Mext_1053 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 163852197 Nonpathogen - hypothetical protein Mext_2778 3 None None None 163852806 Common - iron-sulfur cluster assembly accessory protein Mext_3392 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 163853712 Common - protein of unknown function DUF159 Mext_4315 111 COG2135 COG2135, Uncharacterized conserved protein Function unknown 163851731 Nonpathogen - hypothetical protein Mext_2308 6 None None None 163853794 Common - diguanylate cyclase Mext_4398 174 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163851548 Common - Oxidoreductase FAD-binding domain protein Mext_2125 115 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 163851925 Common - ribosomal subunit interface protein Mext_2502 95 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 163852004 Nonpathogen - hypothetical protein Mext_2583 1 None None None 163853338 Common - ribosomal protein L9 Mext_3939 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 163853709 Common - (Uracil-5)-methyltransferase Mext_4312 183 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 163854202 Common - magnesium-protoporphyrin IX monomethyl ester aerobic oxidative cyclase Mext_4806 20 COG1633 COG1633, Uncharacterized conserved protein Function unknown 163851164 Common - isochorismatase hydrolase Mext_1737 104 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 163853365 Common - Arsenical pump membrane protein Mext_3966 109 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 163850208 Common - transposase Mext_0768 67 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 163853352 Nonpathogen - hypothetical protein Mext_3953 2 None None None 163852583 Common - riboflavin synthase, alpha subunit Mext_3167 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 163849566 Common - hypothetical protein Mext_0110 7 None None None 163852673 Common - cytochrome c oxidase subunit III Mext_3258 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 163850343 Common - cobalamin 5'-phosphate synthase Mext_0910 46 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 163852120 Common - streptogramin A acetyltransferase Mext_2701 67 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 163852959 Common - putative transposase of insertion sequence ISRm10-1 Mext_3551 18 None None None 163850501 Common - methylmalonyl-CoA epimerase Mext_1069 91 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 163850664 Common - phosphocarrier, HPr family Mext_1234 31 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 163849533 Nonpathogen - hypothetical protein Mext_0077 1 None None None 163849571 Common - conserved hypothetical cytosolic protein Mext_0115 4 None None None 163849606 Nonpathogen - hypothetical protein Mext_0152 1 None None None 163853966 Common - peptidyl-prolyl cis-trans isomerase cyclophilin type Mext_4570 198 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 163853468 Common - Endoribonuclease L-PSP Mext_4070 87 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 163851298 Nonpathogen - hypothetical protein Mext_1871 1 None None None 163853744 Common - glycosyl transferase family 2 Mext_4347 121 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163850679 Nonpathogen - hypothetical protein Mext_1249 1 None None None 163853107 Common - hypothetical protein Mext_3703 16 None None None 163853507 Common - KaiB domain protein Mext_4109 24 None None None 163849729 Common - molecular chaperone, HSP70 class Mext_0277 232 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 163853685 Common - tyrosine recombinase XerC Mext_4288 216 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163851964 Common - ubiquinol-cytochrome c reductase, iron-sulfur subunit Mext_2542 107 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 163851105 Common - isochorismatase hydrolase Mext_1678 83 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 163851698 Common - GTP-binding protein Era Mext_2275 237 COG1159 Era, GTPase General function prediction only 163849859 Common - binding-protein-dependent transport systems inner membrane component Mext_0409 29 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 163849543 Common - hypothetical protein Mext_0087 2 None None None 163851182 Common - aminoglycoside phosphotransferase Mext_1755 8 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 163851332 Common - Recombinase Mext_1905 44 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 163854235 Common - protein of unknown function DUF81 Mext_4839 21 COG0730 COG0730, Predicted permeases General function prediction only 163850381 Common - response regulator receiver Mext_0948 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163850582 Common - sigma-54 factor interaction domain-containing protein Mext_1152 172 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 163853036 Nonpathogen - hypothetical protein Mext_3630 1 None None None 163850477 Common - exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase Mext_1044 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 163849731 Nonpathogen - hypothetical protein Mext_0279 1 None None None 163850886 Common - hypothetical protein Mext_1457 31 None None None 163850362 Common - protein of unknown function UPF0153 Mext_0929 75 COG2983 COG2983, Uncharacterized conserved protein Function unknown 163852747 Nonpathogen - hypothetical protein Mext_3332 1 None None None 163854166 Common - Ferritin Dps family protein Mext_4770 136 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 163853001 Nonpathogen - hypothetical protein Mext_3595 1 None None None 163854084 Nonpathogen - hypothetical protein Mext_4688 1 None None None 163851842 Nonpathogen - hypothetical protein Mext_2419 1 None None None 163854092 Common - type I secretion outer membrane protein, TolC family Mext_4696 136 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 163853151 Common - histidinol-phosphate phosphatase Mext_3749 187 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 163850288 Common - glycine cleavage system T protein Mext_0855 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 163851251 Common - formylmethanofuran dehydrogenase subunit C Mext_1824 25 COG2218 FwdC, Formylmethanofuran dehydrogenase subunit C Energy production and conversion 163853469 Common - ABC transporter related Mext_4071 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 163849579 Common - PAS sensor protein Mext_0123 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163853073 Common - aldehyde oxidase and xanthine dehydrogenase molybdopterin binding Mext_3667 118 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 163851873 Nonpathogen - hypothetical protein Mext_2450 1 None None None 163851579 Common - conserved hypothetical proteinn Mext_2156 16 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 163850276 Common - transcriptional regulator, XRE family Mext_0843 21 COG5606 COG5606, Uncharacterized conserved small protein Function unknown 163852985 Common - regulatory protein LuxR Mext_3579 157 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163852152 Nonpathogen - hypothetical protein Mext_2733 1 None None None 163852796 Common - ATP-binding region ATPase domain protein Mext_3382 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163853732 Common - cytochrome o ubiquinol oxidase, subunit III Mext_4335 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 163849893 Common - integrase, catalytic region Mext_0443 19 None None None 163853300 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family Mext_3901 129 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 163849785 Common - Lysine exporter protein (LYSE/YGGA) Mext_0333 119 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 163851119 Common - hypothetical protein Mext_1692 23 None None None 163851255 Common - beta-ribofuranosylaminobenzene 5'-phosphate synthase family Mext_1828 34 COG1907 COG1907, Predicted archaeal sugar kinases General function prediction only 163850642 Common - major facilitator superfamily MFS_1 Mext_1212 106 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 163853541 Common - MxaA protein, putative Mext_4144 9 None None None 163849487 Common - general secretion pathway protein D Mext_0031 142 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 163852988 Nonpathogen - hypothetical protein Mext_3582 1 None None None 163851647 Common - glycosyl transferase group 1 Mext_2224 110 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163849987 Common - arginase Mext_0544 102 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 163850808 Common - protein of unknown function DUF461 Mext_1379 78 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 163850825 Common - penicillin-binding protein 1C Mext_1396 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 163850874 Nonpathogen - Protein of unknown function DUF1772 Mext_1445 4 None None None 163851201 Common - rhodanese Mext_1774 14 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 163852887 Common - FAD linked oxidase domain protein Mext_3474 193 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 163853319 Nonpathogen - hypothetical protein Mext_3920 1 None None None 163851624 Nonpathogen - hypothetical protein Mext_2201 2 None None None 163851583 Common - translation elongation factor Tu Mext_2160 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 163849666 Common - C4-dicarboxylate transporter/malic acid transport protein Mext_0212 47 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 163849953 Common - Radical SAM domain protein Mext_0509 79 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 163852576 Common - thiamine-monophosphate kinase Mext_3160 196 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 163854010 Common - NADH dehydrogenase (quinone) Mext_4614 199 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 163850985 Common - major facilitator superfamily MFS_1 Mext_1558 17 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163851379 Common - Ethanolamine ammonia lyase large subunit Mext_1952 55 COG4303 EutB, Ethanolamine ammonia-lyase, large subunit Amino acid transport and metabolism 163849808 Common - Hemolysin-type calcium-binding region Mext_0358 54 None None None 163851141 Common - NAD(P)H dehydrogenase (quinone) Mext_1714 51 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 163851505 Common - outer membrane protein assembly complex, YaeT protein Mext_2081 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 163851439 Nonpathogen - hypothetical protein Mext_2013 1 None None None 163852307 Common - cell wall hydrolase SleB Mext_2889 45 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 163853333 Common - beta-lactamase domain protein Mext_3934 55 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 163850225 Common - cyclic nucleotide-binding Mext_0788 28 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163851780 Common - Pyridoxal-5'-phosphate-dependent protein beta subunit Mext_2357 55 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 163853081 Common - glycosyl transferase family 2 Mext_3675 57 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 163853204 Common - aldo/keto reductase Mext_3802 165 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 163851241 Common - dihydropteroate synthase Mext_1814 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 163851815 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Mext_2392 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 163852260 Common - PAS sensor protein Mext_2842 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163854146 Common - major facilitator superfamily MFS_1 Mext_4750 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163850243 Nonpathogen - hypothetical protein Mext_0810 1 None None None 163850360 Common - protein of unknown function DUF1214 Mext_0927 19 COG5402 COG5402, Uncharacterized conserved protein Function unknown 163851728 Common - Radical SAM domain protein Mext_2305 55 COG4277 COG4277, Predicted DNA-binding protein with the Helix-hairpin-helix motif General function prediction only 163852617 Common - MEKHLA domain protein Mext_3202 19 None None None 163849865 Common - Heavy metal transport/detoxification protein Mext_0415 10 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 163851484 Common - protein of unknown function DUF444 Mext_2060 71 COG2718 COG2718, Uncharacterized conserved protein Function unknown 163851520 Common - acyl-CoA thioesterase II Mext_2097 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 163850662 Common - glycosyl transferase family 2 Mext_1232 18 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163852539 Common - major facilitator superfamily MFS_1 Mext_3123 102 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163850608 Common - cysteine desulfurase, SufS subfamily Mext_1178 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 163850767 Common - extracellular solute-binding protein family 3 Mext_1338 26 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 163850547 Common - ribonuclease BN Mext_1115 73 COG1295 Rbn, Predicted membrane protein Function unknown 163850948 Common - protein of unknown function DUF1330 Mext_1521 20 COG5470 COG5470, Uncharacterized conserved protein Function unknown 163853252 Common - aldo/keto reductase Mext_3852 200 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 163852784 Common - cyclase family protein Mext_3370 88 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 163850750 Common - short-chain dehydrogenase/reductase SDR Mext_1321 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 163853938 Common - PAS sensor protein Mext_4542 105 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163854285 Common - integrase family protein Mext_4889 29 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163852517 Nonpathogen - hypothetical protein Mext_3101 1 None None None 163852270 Common - extracellular solute-binding protein family 1 Mext_2852 62 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 163852830 Common - protein of unknown function DUF404 Mext_3416 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 163850161 Common - glutamine amidotransferase class-I Mext_0721 165 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 163850881 Nonpathogen - hypothetical protein Mext_1452 1 None None None 163850379 Common - dihydrouridine synthase DuS Mext_0946 146 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 163852200 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Mext_2781 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 163850436 Nonpathogen - hypothetical protein Mext_1003 1 None None None 163853720 Common - glycoside hydrolase 15-related Mext_4323 69 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 163849888 Common - hypothetical protein Mext_0438 7 None None None 163853657 Common - glycosyl transferase family 2 Mext_4260 177 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163850212 Common - hypothetical protein Mext_0774 3 None None None 163851134 Common - protein of unknown function DUF81 Mext_1707 70 COG0730 COG0730, Predicted permeases General function prediction only 163850354 Nonpathogen - hypothetical protein Mext_0921 4 None None None 163851226 Common - succinyl-CoA synthetase, beta subunit Mext_1799 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 163853797 Common - protein of unknown function DUF427 Mext_4401 43 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 163850428 Common - molybdenum cofactor biosynthesis protein B Mext_0995 190 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 163849826 Common - methyltransferase FkbM family Mext_0376 54 COG2520 COG2520, Predicted methyltransferase General function prediction only 163850876 Common - Adenosylcobinamide-phosphate guanylyltransferase Mext_1447 127 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 163851328 Common - Integrase catalytic region Mext_1901 115 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 163849511 Common - transposase IS4 family protein Mext_0055 64 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 163852837 Common - Aldehyde Dehydrogenase_ Mext_3423 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 163851937 Common - glycoside hydrolase family 3 domain protein Mext_2514 122 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 163851334 Common - arsenical resistance protein ArsH Mext_1907 64 COG0431 COG0431, Predicted flavoprotein General function prediction only 163850308 Common - PAS sensor protein Mext_0875 152 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163850468 Nonpathogen - putative CobE protein Mext_1035 8 None None None 163853586 Nonpathogen - hypothetical protein Mext_4189 1 None None None 163850525 Common - LysR substrate-binding Mext_1093 186 COG0583 LysR, Transcriptional regulator Transcription 163851430 Common - cob(II)yrinic acid a,c-diamide reductase Mext_2003 96 COG0778 NfnB, Nitroreductase Energy production and conversion 163853207 Nonpathogen - hypothetical protein Mext_3805 1 None None None 163853623 Common - protein of unknown function DUF498 Mext_4226 30 COG3737 COG3737, Uncharacterized conserved protein Function unknown 163853585 Nonpathogen - hypothetical protein Mext_4188 1 None None None 163849871 Common - Glyoxylate reductase Mext_0421 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 163853260 Common - methyltransferase Mext_3860 196 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 163849590 Common - rare lipoprotein A Mext_0135 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 163851077 Common - hypothetical protein Mext_1650 2 None None None 163849834 Nonpathogen - hypothetical protein Mext_0384 10 None None None 163852736 Nonpathogen - hypothetical protein Mext_3321 1 None None None 163853014 Nonpathogen - hypothetical protein Mext_3608 1 None None None 163851233 Common - putative ABC transporter periplasmic solute-binding protein Mext_1806 14 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163852241 Common - sigma-54 factor interaction domain-containing protein Mext_2823 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163850723 Common - aminotransferase class-III Mext_1294 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 163849881 Common - Oligopeptidase B Mext_0431 100 COG1770 PtrB, Protease II Amino acid transport and metabolism 163850063 Common - flagellar basal-body rod protein FlgG Mext_0621 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 163851445 Common - protein of unknown function DUF477 Mext_2019 87 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 163852850 Common - phytoene desaturase Mext_3436 82 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 163849589 Nonpathogen - hypothetical protein Mext_0134 1 None None None 163853237 Common - beta-lactamase domain protein Mext_3837 188 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 163853095 Common - dTDP-glucose 4,6-dehydratase Mext_3691 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 163854273 Common - PAS sensor protein Mext_4877 111 COG4566 TtrR, Response regulator Signal transduction mechanisms 163853269 Common - short-chain dehydrogenase/reductase SDR Mext_3869 209 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 163854225 Common - ABC transporter related Mext_4829 245 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 163853569 Nonpathogen - hypothetical protein Mext_4172 1 None None None 163853240 Nonpathogen - tetratricopeptide TPR_4 Mext_3840 1 None None None 163852509 Common - poly(R)-hydroxyalkanoic acid synthase, class I Mext_3093 75 COG3243 PhaC, Poly(3-hydroxyalkanoate) synthetase Lipid metabolism 163851003 Common - response regulator receiver Mext_1576 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163854057 Common - CTP synthase Mext_4661 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 163854214 Common - cobalamin B12-binding Mext_4818 14 COG5012 COG5012, Predicted cobalamin binding protein General function prediction only 163852512 Common - glycyl-tRNA synthetase, beta subunit Mext_3096 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 163853929 Common - phosphoenolpyruvate carboxylase Mext_4533 85 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 163853424 Common - TonB-dependent siderophore receptor Mext_4026 96 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 163854127 Common - acetyl-CoA carboxylase, carboxyl transferase, alpha subunit Mext_4731 176 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 163850210 Common - cyclic nucleotide-binding Mext_0772 62 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163850322 Common - hypothetical protein Mext_0889 12 None None None 163851357 Common - Alpha/beta hydrolase fold-3 domain protein Mext_1930 112 COG0657 Aes, Esterase/lipase Lipid metabolism 163854266 Common - RNA polymerase sigma factor, sigma-70 family Mext_4870 169 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 163853272 Nonpathogen - hypothetical protein Mext_3872 2 None None None 163849747 Nonpathogen - hypothetical protein Mext_0295 1 None None None 163852279 Common - hypoxanthine phosphoribosyltransferase Mext_2861 152 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 163850022 Nonpathogen - hypothetical protein Mext_0579 1 None None None 163852429 Common - Squalene/phytoene synthase Mext_3012 97 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 163854192 Common - protein of unknown function DUF817 Mext_4796 24 COG3739 COG3739, Uncharacterized integral membrane protein Function unknown 163850816 Common - Tripartite ATP-independent periplasmic transporter DctQ component Mext_1387 54 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 163851206 Nonpathogen - hypothetical protein Mext_1779 1 None None None 163850300 Common - Tetratricopeptide TPR_2 repeat protein Mext_0867 31 None None None 163853573 Nonpathogen - hypothetical protein Mext_4176 2 None None None 163852289 Nonpathogen - hypothetical protein Mext_2871 2 None None None 163853513 Nonpathogen - hypothetical protein Mext_4115 1 COG3212 COG3212, Predicted membrane protein Function unknown 163853223 Common - alpha/beta hydrolase fold Mext_3822 176 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163850136 Common - dihydrodipicolinate synthetase Mext_0696 184 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 163849608 Common - helix-turn-helix domain protein Mext_0154 45 COG1396 HipB, Predicted transcriptional regulators Transcription 163849891 Common - putative insertion element protein Mext_0441 45 None None None 163853392 Common - ABC transporter related Mext_3993 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 163854007 Common - monovalent cation/proton antiporter, MnhG/PhaG subunit Mext_4611 7 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 163849775 Common - PhoH family protein Mext_0323 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 163850859 Common - peptidase S1 and S6 chymotrypsin/Hap Mext_1430 24 COG5640 COG5640, Secreted trypsin-like serine protease Posttranslational modification, protein turnover, chaperones 163852280 Nonpathogen - MJ0042 family finger-like protein Mext_2862 9 None None None 163852186 Nonpathogen - hypothetical protein Mext_2767 1 None None None 163854035 Common - Peptidoglycan glycosyltransferase Mext_4639 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 163854023 Common - Phosphoglycerate mutase Mext_4627 85 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 163853645 Common - peptidase S58 DmpA Mext_4248 51 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163850748 Common - protein of unknown function DUF112 transmembrane Mext_1319 77 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 163853908 Nonpathogen - hypothetical protein Mext_4512 1 None None None 163854136 Common - phosphatidylserine decarboxylase related protein Mext_4740 94 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 163851600 Common - beta-lactamase domain protein Mext_2177 59 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 163852477 Common - ATP-binding region ATPase domain protein Mext_3060 218 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163853055 Common - permease YjgP/YjgQ family protein Mext_3649 80 COG0795 COG0795, Predicted permeases General function prediction only 163853231 Common - AcrB/AcrD/AcrF family protein Mext_3830 175 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163852093 Common - 2-isopropylmalate synthase Mext_2674 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 163849532 Nonpathogen - hypothetical protein Mext_0076 2 None None None 163851410 Common - hypothetical protein Mext_1983 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 163850793 Common - Amidase Mext_1364 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 163852713 Common - Superoxide dismutase Mext_3298 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 163853350 Common - TonB-dependent receptor plug Mext_3951 90 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 163851070 Common - malate dehydrogenase, NAD-dependent Mext_1643 191 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 163851159 Common - binding-protein-dependent transport systems inner membrane component Mext_1732 81 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163850857 Nonpathogen - phiE125 gp8 family protein Mext_1428 4 None None None 163850372 Common - glutathione synthetase Mext_0939 126 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 163851757 Common - response regulator receiver Mext_2334 54 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163853671 Common - binding-protein-dependent transport systems inner membrane component Mext_4274 215 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 163849473 Nonpathogen - hypothetical protein Mext_0016 1 None None None 163851311 Common - protein of unknown function DUF937 Mext_1884 22 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 163852556 Common - hypothetical protein Mext_3140 17 None None None 163853955 Common - histidinol-phosphate phosphatase Mext_4559 186 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 163852165 Common - protein of unknown function DUF1036 Mext_2746 18 COG5480 COG5480, Predicted integral membrane protein Function unknown 163849824 Common - molybdopterin binding domain Mext_0374 166 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 163851897 Common - Aminoacyl-tRNA hydrolase Mext_2474 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 163850011 Common - monooxygenase FAD-binding Mext_0568 104 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 163850367 Common - AFG1-family ATPase Mext_0934 101 COG1485 COG1485, Predicted ATPase General function prediction only 163851344 Nonpathogen - hypothetical protein Mext_1917 1 None None None 163851100 Common - NmrA family protein Mext_1673 139 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163849611 Nonpathogen - hypothetical protein Mext_0157 1 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 163852293 Common - periplasmic solute binding protein Mext_2875 166 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 163850097 Nonpathogen - hypothetical protein Mext_0655 6 None None None 163853827 Common - protein of unknown function UPF0079 Mext_4431 201 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 163853832 Common - Enoyl-CoA hydratase/isomerase Mext_4436 175 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 163850171 Common - PAS sensor protein Mext_0731 162 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163850593 Common - hypothetical protein Mext_1163 87 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 163850891 Common - NUDIX hydrolase Mext_1462 132 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 163851514 Common - short-chain dehydrogenase/reductase SDR Mext_2090 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163851483 Common - PrkA AAA domain protein Mext_2059 70 COG2766 PrkA, Putative Ser protein kinase Signal transduction mechanisms 163852410 Common - histone deacetylase superfamily Mext_2993 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 163853019 Common - magnesium and cobalt transport protein CorA Mext_3613 154 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 163849469 Common - BolA family protein Mext_0012 86 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 163850709 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mext_1280 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 163853667 Common - OsmC family protein Mext_4270 40 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 163850787 Common - ABC transporter related Mext_1358 211 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 163850640 Common - Galactose oxidase Mext_1210 14 None None None 163851959 Common - Capsule polysaccharide biosynthesis protein Mext_2537 30 COG3563 KpsC, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 163852895 Nonpathogen - hypothetical protein Mext_3482 5 None None None 163849709 Common - Superfamily II helicase and inactivated derivatives-like protein Mext_0257 22 COG5519 COG5519, Superfamily II helicase and inactivated derivatives DNA replication, recombination, and repair 163852448 Nonpathogen - hypothetical protein Mext_3031 1 None None None 163851954 Common - TRAP dicarboxylate transporter- DctP subunit Mext_2532 74 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 163851363 Common - hypothetical protein Mext_1936 5 None None None 163852530 Nonpathogen - hypothetical protein Mext_3114 1 None None None 163852435 Common - metal-dependent phosphohydrolase HD sub domain Mext_3018 204 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 163852040 Common - ribosomal protein S9 Mext_2620 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 163853533 Nonpathogen - hypothetical protein Mext_4136 1 None None None 163850398 Common - hypothetical protein Mext_0965 21 None None None 163852070 Common - molybdenum cofactor biosynthesis protein A Mext_2650 196 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 163850345 Common - ATP-binding region ATPase domain protein Mext_0912 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163851318 Common - Urea carboxylase Mext_1891 46 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 163851770 Common - metallophosphoesterase Mext_2347 142 None None None 163849671 Common - Polysulphide reductase NrfD Mext_0217 39 COG5557 COG5557, Polysulphide reductase Energy production and conversion 163851563 Common - AMP-dependent synthetase and ligase Mext_2140 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163852797 Common - response regulator receiver Mext_3383 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163851050 Common - glycosyl transferase group 1 Mext_1623 103 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163851490 Common - chromosomal replication initiator DnaA Mext_2066 68 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 163849944 Nonpathogen - hypothetical protein Mext_0500 12 COG3664 XynB, Beta-xylosidase Carbohydrate transport and metabolism 163853418 Common - Endoribonuclease L-PSP Mext_4020 73 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 163850573 Common - protein of unknown function DUF395 YeeE/YedE Mext_1142 56 COG2391 COG2391, Predicted transporter component General function prediction only 163850411 Common - LysR substrate-binding Mext_0978 190 COG0583 LysR, Transcriptional regulator Transcription 163849752 Nonpathogen - hypothetical protein Mext_0300 2 None None None 163852503 Nonpathogen - hypothetical protein Mext_3087 1 None None None 163850935 Common - carbonic anhydrase/acetyltransferase isoleucine patch superfamily-like protein Mext_1506 181 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 163852310 Nonpathogen - hypothetical protein Mext_2892 1 None None None 163850639 Common - oxalyl-CoA decarboxylase Mext_1209 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 163851027 Common - 5,10-methylenetetrahydrofolate reductase Mext_1600 140 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 163852978 Nonpathogen - O-antigen polymerase Mext_3570 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 163849520 Common - hypothetical protein Mext_0064 10 None None None 163853117 Common - dTDP-4-dehydrorhamnose reductase Mext_3714 152 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 163850147 Common - chemotaxis sensory transducer Mext_0707 30 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163854207 Common - PUCC protein Mext_4811 23 None None None 163852343 Common - ABC transporter related Mext_2926 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 163853766 Common - hypothetical protein Mext_4369 18 None None None 163850197 Common - Stress responsive alpha-beta barrel domain protein Mext_0757 14 None None None 163853324 Common - hypothetical protein Mext_3925 10 COG2348 COG2348, Uncharacterized protein involved in methicillin resistance Defense mechanisms 163852497 Common - serine/threonine protein kinase Mext_3080 35 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 163849460 Common - DNA replication and repair protein RecF Mext_0003 161 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 163853604 Common - collagen triple helix repeat Mext_4207 16 None None None 163852077 Common - HflC protein Mext_2657 214 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 163849903 Nonpathogen - hypothetical protein Mext_0454 1 None None None 163849857 Common - response regulator receiver Mext_0407 48 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163853692 Common - pyridoxamine 5'-phosphate oxidase Mext_4295 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 163852876 Common - carbohydrate kinase, thermoresistant glucokinase family Mext_3463 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 163853297 Common - regulatory protein Crp Mext_3898 34 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163849634 Common - signal peptide peptidase SppA, 36K type Mext_0180 145 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 163852543 Common - SWIB/MDM2 domain protein Mext_3127 16 COG5531 COG5531, SWIB-domain-containing proteins implicated in chromatin remodeling Chromatin structure and dynamics 163852234 Common - CinA domain protein Mext_2816 191 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 163852750 Common - chaperonin Cpn10 Mext_3335 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 163852974 Common - glycosyl transferase group 1 Mext_3566 178 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163851263 Common - H4MPT-linked C1 transfer pathway protein Mext_1836 24 COG1548 COG1548, Predicted transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 163854067 Common - anthranilate phosphoribosyltransferase Mext_4671 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 163852521 Common - peptidase S49 Mext_3105 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 163849715 Nonpathogen - hypothetical protein Mext_0263 1 None None None 163849681 Nonpathogen - hypothetical protein Mext_0227 1 None None None 163852851 Common - glutamine amidotransferase class-I Mext_3437 96 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 163850316 Nonpathogen - hypothetical protein Mext_0883 1 None None None 163850073 Common - OmpA/MotB domain protein Mext_0631 115 COG1360 MotB, Flagellar motor protein Cell motility and secretion 163854243 Common - GSCFA domain protein Mext_4847 16 None None None 163851121 Nonpathogen - hypothetical protein Mext_1694 1 None None None 163852633 Common - protein of unknown function DUF323 Mext_3218 88 COG1262 COG1262, Uncharacterized conserved protein Function unknown 163853402 Common - acyltransferase 3 Mext_4003 26 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 163850048 Common - adenylyl cyclase class-3/4/guanylyl cyclase Mext_0606 74 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 163854161 Common - tol-pal system-associated acyl-CoA thioesterase Mext_4765 112 COG0824 FcbC, Predicted thioesterase General function prediction only 163853893 Common - putative nitrate transport protein Mext_4497 80 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163853072 Common - molybdopterin dehydrogenase FAD-binding Mext_3666 85 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 163849626 Common - hypothetical protein Mext_0172 6 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163851286 Common - lipopolysaccharide biosynthesis protein Mext_1859 44 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 163850823 Common - protein of unknown function DUF606 Mext_1394 4 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 163852408 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Mext_2991 227 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 163852148 Common - chlorophyll synthesis pathway, BchC Mext_2729 70 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 163849654 Common - HAD-superfamily hydrolase, subfamily IIB Mext_0200 97 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163850122 Common - ATPase, FliI/YscN family Mext_0682 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 163850494 Common - short-chain dehydrogenase/reductase SDR Mext_1061 221 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163854017 Common - glycosyl transferase, WecB/TagA/CpsF family Mext_4621 111 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 163852112 Nonpathogen - hypothetical protein Mext_2693 1 None None None 163852963 Common - protein of unknown function DUF218 Mext_3555 85 COG1434 COG1434, Uncharacterized conserved protein Function unknown 163853820 Common - diacylglycerol kinase catalytic region Mext_4424 84 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 163849665 Common - aldehyde oxidase and xanthine dehydrogenase molybdopterin binding Mext_0211 113 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 163851194 Common - hypothetical protein Mext_1767 6 COG3652 COG3652, Predicted outer membrane protein Function unknown 163853742 Common - regulatory protein LuxR Mext_4345 166 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163850281 Common - C-methyltransferase Mext_0848 44 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 163853996 Common - thiamine pyrophosphate protein domain protein TPP-binding Mext_4600 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 163851987 Common - major facilitator superfamily MFS_1 Mext_2565 114 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163849518 Common - isochorismatase hydrolase Mext_0062 76 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 163850055 Common - major royal jelly protein Mext_0613 15 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 163851635 Nonpathogen - hypothetical protein Mext_2212 1 None None None 163851055 Common - ribosomal protein L20 Mext_1628 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 163850331 Nonpathogen - conserved hypothetical protein; putative signal peptide Mext_0898 2 COG4982 COG4982, 3-oxoacyl- acyl-carrier protein 163850780 Common - Cupin 2 conserved barrel domain protein Mext_1351 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 163851616 Common - nuclease (SNase domain protein) Mext_2193 18 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 163854077 Common - glutamyl-tRNA synthetase Mext_4681 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 163853025 Nonpathogen - hypothetical protein Mext_3619 2 None None None 163852038 Common - transglutaminase domain protein Mext_2618 82 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 163852565 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Mext_3149 208 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 163853683 Nonpathogen - hypothetical protein Mext_4286 1 None None None 163851214 Common - diaminopimelate decarboxylase Mext_1787 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 163850151 Common - protein of unknown function DUF201 Mext_0711 23 COG0439 AccC, Biotin carboxylase Lipid metabolism 163850716 Common - inner-membrane translocator Mext_1287 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 163852315 Common - hypothetical protein Mext_2898 14 None None None 163853409 Common - Prephenate dehydrogenase Mext_4010 76 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 163849878 Common - DoxX family protein Mext_0428 26 COG2259 COG2259, Predicted membrane protein Function unknown 163850172 Common - metalloendopeptidase, glycoprotease family Mext_0732 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 163849846 Common - efflux transporter, RND family, MFP subunit Mext_0396 155 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163852680 Nonpathogen - putative exported protein of unknown function Mext_3265 5 COG2511 GatE, Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) Translation, ribosomal structure and biogenesis 163849850 Nonpathogen - hypothetical protein Mext_0400 1 None None None 163850254 Common - hypothetical protein Mext_0821 52 COG0392 COG0392, Predicted integral membrane protein Function unknown 163852042 Common - TOBE domain protein Mext_2622 72 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 163852746 Common - 2OG-Fe(II) oxygenase Mext_3331 54 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 163852102 Common - protein of unknown function DUF181 Mext_2683 26 COG1944 COG1944, Uncharacterized conserved protein Function unknown 163849688 Common - potassium-transporting ATPase, C subunit Mext_0235 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 163850839 Nonpathogen - hypothetical protein Mext_1410 3 COG5346 COG5346, Predicted membrane protein Function unknown 163850269 Common - molybdopterin dehydrogenase FAD-binding Mext_0836 97 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 163851088 Common - transposase and inactivated derivatives-like protein Mext_1661 21 None None None 163850864 Common - precorrin-3B C17-methyltransferase Mext_1435 118 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 163851794 Common - Sel1 domain protein repeat-containing protein Mext_2371 100 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 163853750 Nonpathogen - hypothetical protein Mext_4353 5 None None None 163853520 Nonpathogen - hypothetical protein Mext_4122 1 None None None 163850941 Common - zinc finger SWIM domain protein Mext_1514 15 COG4715 COG4715, Uncharacterized conserved protein Function unknown 163854078 Common - ComEC/Rec2-related protein Mext_4682 89 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 163854094 Nonpathogen - hypothetical protein Mext_4698 1 None None None 163852816 Common - hypothetical protein Mext_3402 10 None None None 163853505 Common - PAS sensor protein Mext_4107 215 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163850517 Common - NADH-ubiquinone/plastoquinone oxidoreductase chain 3 Mext_1085 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 163853197 Common - MATE efflux family protein Mext_3795 122 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 163849976 Common - Na+/H+ antiporter Mext_0533 90 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 163852595 Common - A/G-specific adenine glycosylase Mext_3180 186 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 163852360 Nonpathogen - putative phage-related transcriptional regulator Mext_2943 1 None None None 163849535 Nonpathogen - hypothetical protein Mext_0079 1 None None None 163852853 Common - ABC transporter related Mext_3439 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 163850378 Nonpathogen - hypothetical protein Mext_0945 1 None None None 163851580 Common - ribosomal protein S12 Mext_2157 241 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 163853432 Common - cell divisionFtsK/SpoIIIE Mext_4034 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 163851401 Common - putative DNA topoisomerase I Mext_1974 45 COG3569 COG3569, Topoisomerase IB DNA replication, recombination, and repair 163853527 Common - exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase Mext_4130 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 163851278 Common - ABC-2 type transporter Mext_1851 158 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 163851044 Common - protein TolR Mext_1617 144 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 163851340 Nonpathogen - hypothetical protein Mext_1913 2 None None None 163850602 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Mext_1172 73 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163850503 Common - biotin--acetyl-CoA-carboxylase ligase Mext_1071 174 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 163854114 Common - phosphate regulon transcriptional regulatory protein PhoB Mext_4718 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163853555 Common - protein of unknown function DUF336 Mext_4158 84 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 163849992 Common - NAD(+) kinase Mext_0549 234 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 163849568 Nonpathogen - hypothetical protein Mext_0112 1 None None None 163852752 Common - hypothetical protein Mext_3337 8 None None None 163853395 Common - preprotein translocase, SecE subunit Mext_3996 17 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 163852081 Nonpathogen - Abortive infection protein Mext_2661 1 None None None 163853190 Common - Resolvase domain Mext_3788 26 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 163852335 Common - AsmA family protein Mext_2918 16 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 163853442 Common - protein of unknown function DUF81 Mext_4044 26 COG0730 COG0730, Predicted permeases General function prediction only 163851708 Common - chemotaxis sensory transducer Mext_2285 59 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163849627 Common - hypothetical protein Mext_0173 11 None None None 163853139 Common - sarcosine oxidase, delta subunit family Mext_3737 35 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 163852794 Common - urea ABC transporter, permease protein UrtB Mext_3380 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 163853034 Common - alpha/beta hydrolase fold Mext_3628 108 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163849650 Common - hypothetical protein Mext_0196 7 None None None 163852871 Common - hypothetical protein Mext_3457 2 None None None 163849971 Common - putative RND superfamily transporter Mext_0528 16 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 163850129 Common - flagellar biosynthetic protein FliQ Mext_0689 120 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 163849761 Common - Methyltransferase type 11 Mext_0309 70 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163852588 Common - H+transporting two-sector ATPase B/B' subunit Mext_3173 42 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 163853167 Common - GCN5-related N-acetyltransferase Mext_3765 92 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 163850802 Common - glycosyl transferase group 1 Mext_1373 93 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163852931 Common - hypothetical protein Mext_3519 21 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 163851737 Common - Catalase domain protein Mext_2314 124 COG0753 KatE, Catalase Inorganic ion transport and metabolism 163851819 Common - hypothetical protein Mext_2396 11 None None None 163853277 Common - quinone oxidoreductase, YhdH/YhfP family Mext_3877 111 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 163849896 Nonpathogen - hypothetical protein Mext_0446 1 None None None 163851867 Nonpathogen - hypothetical protein Mext_2444 1 None None None 163853651 Nonpathogen - hypothetical protein Mext_4254 4 None None None 163853265 Common - arsenate reductase Mext_3865 110 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 163850030 Common - glycosyl transferase family 2 Mext_0588 67 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163850131 Common - putative flagellar biosynthetic protein Mext_0691 106 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 163851154 Common - guanine deaminase Mext_1727 152 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 163854277 Nonpathogen - hypothetical protein Mext_4881 1 None None None 163851837 Common - multicopper oxidase type 3 Mext_2414 126 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 163853439 Common - NnrUfamily protein Mext_4041 35 COG4094 COG4094, Predicted membrane protein Function unknown 163853970 Common - hypothetical protein Mext_4574 28 COG4544 COG4544, Uncharacterized conserved protein Function unknown 163850008 Common - ABC transporter related Mext_0565 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 163852351 Common - Fmu (Sun) domain protein Mext_2934 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 163852456 Nonpathogen - hypothetical protein Mext_3039 1 None None None 163850532 Common - conserved hypothetical proteinn Mext_1100 29 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 163849989 Nonpathogen - hypothetical protein Mext_0546 1 None None None 163852011 Common - multi antimicrobial extrusion protein MatE Mext_2591 96 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 163853800 Common - NADH dehydrogenase (ubiquinone) 24 kDa subunit Mext_4404 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 163853017 Common - short-chain dehydrogenase/reductase SDR Mext_3611 30 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163849560 Common - lipolytic protein G-D-S-L family Mext_0104 47 COG3240 COG3240, Phospholipase/lecithinase/hemolysin Lipid metabolism / General function prediction only 163851852 Nonpathogen - hypothetical protein Mext_2429 1 None None None 163854009 Common - cation antiporter Mext_4613 65 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 163852643 Common - hypothetical protein Mext_3228 13 None None None 163851555 Common - glycosyl transferase family 28 Mext_2132 52 COG1819 COG1819, Glycosyl transferases, related to UDP-glucuronosyltransferase Carbohydrate transport and metabolism / Signal transduction mechanisms 163849588 Common - regulatory protein MarR Mext_0133 75 COG1846 MarR, Transcriptional regulators Transcription 163850762 Common - ApbE family lipoprotein Mext_1333 133 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 163852054 Common - heme exporter protein CcmB Mext_2634 97 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 163849772 Common - hypothetical protein Mext_0320 14 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 163853846 Common - DEAD/DEAH box helicase domain protein Mext_4450 237 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 163849787 Common - protein-P-II uridylyltransferase Mext_0335 126 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 163851111 Common - Antibiotic biosynthesis monooxygenase Mext_1684 16 COG1359 COG1359, Uncharacterized conserved protein Function unknown 163853599 Common - hydroxypyruvate isomerase Mext_4202 82 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 163849920 Nonpathogen - hypothetical protein Mext_0471 1 None None None 163851534 Common - serine O-acetyltransferase Mext_2111 193 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 163851388 Nonpathogen - hypothetical protein Mext_1961 1 None None None 163851685 Common - CBS domain containing protein Mext_2262 186 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 163850915 Common - protein of unknown function DUF497 Mext_1486 39 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 163853812 Common - hypothetical protein Mext_4416 9 None None None 163849597 Common - integrase, catalytic region Mext_0142 23 None None None 163853212 Common - hypothetical protein Mext_3810 7 None None None 163851210 Common - protein of unknown function DUF463 YcjX family protein Mext_1783 42 COG3106 COG3106, Predicted ATPase General function prediction only 163850627 Common - urease, alpha subunit Mext_1197 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 163852822 Common - Alkanesulfonate monooxygenase Mext_3408 81 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 163849720 Common - Resolvase domain Mext_0268 102 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 163850529 Common - Leucyltransferase Mext_1097 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 163852029 Common - hypothetical protein Mext_2609 11 COG5373 COG5373, Predicted membrane protein Function unknown 163852742 Common - efflux transporter, RND family, MFP subunit Mext_3327 137 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163853796 Common - HAD-superfamily hydrolase, subfamily IIB Mext_4400 85 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 163852367 Common - UDP-3-0-acyl N-acetylglucosamine deacetylase Mext_2950 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 163852022 Common - PAS sensor protein Mext_2602 225 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163851957 Common - polysaccharide export protein Mext_2535 62 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 163850624 Common - UreE urease accessory domain protein Mext_1194 8 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 163851849 Common - Hemolysin-type calcium-binding region Mext_2426 76 None None None 163851976 Common - pantothenate kinase Mext_2554 80 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 163853160 Common - FecR protein Mext_3758 50 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 163852397 Common - lysyl-tRNA synthetase Mext_2980 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 163853626 Common - preprotein translocase, YajC subunit Mext_4229 168 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 163853948 Common - hypothetical protein Mext_4552 12 None None None 163849657 Nonpathogen - glycosyl transferase family 2 Mext_0203 13 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163851591 Common - ribosomal protein S3 Mext_2168 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 163850258 Common - hypothetical protein Mext_0825 30 None None None 163849991 Common - CutA1 divalent ion tolerance protein Mext_0548 116 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 163852660 Common - acyl-CoA dehydrogenase domain protein Mext_3245 151 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 163853031 Common - DNA-(apurinic or apyrimidinic site) lyase Mext_3625 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 163850156 Nonpathogen - hypothetical protein Mext_0716 1 None None None 163850092 Nonpathogen - hypothetical protein Mext_0650 2 None None None 163850906 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Mext_1477 167 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 163851423 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Mext_1996 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 163852199 Nonpathogen - hypothetical protein Mext_2780 1 None None None 163850754 Nonpathogen - hypothetical protein Mext_1325 3 None None None 163850653 Nonpathogen - hypothetical protein Mext_1223 1 None None None 163850475 Common - Antibiotic biosynthesis monooxygenase Mext_1042 34 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 163850619 Common - putative ABC-type Co2+ transport system, periplasmic component Mext_1189 13 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 163852693 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Mext_3278 196 COG0388 COG0388, Predicted amidohydrolase General function prediction only 163850541 Common - Endoribonuclease L-PSP Mext_1109 119 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 163850562 Common - hypothetical protein Mext_1130 31 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 163854025 Common - plasmid stabilization system Mext_4629 7 COG3668 ParE, Plasmid stabilization system protein General function prediction only 163854255 Common - PAS fold-3 domain protein Mext_4859 67 None None None 163850843 Nonpathogen - hypothetical protein Mext_1414 1 None None None 163851751 Common - peptidase M16 domain protein Mext_2328 201 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 163853590 Common - binding-protein-dependent transport systems inner membrane component Mext_4193 123 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 163849693 Nonpathogen - hypothetical protein Mext_0240 12 COG3664 XynB, Beta-xylosidase Carbohydrate transport and metabolism 163854090 Common - valyl-tRNA synthetase Mext_4694 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163852667 Nonpathogen - hypothetical protein Mext_3252 1 None None None 163853486 Common - sigma-54 factor interaction domain-containing protein Mext_4088 171 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163851223 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mext_1796 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 163854233 Common - hypothetical protein Mext_4837 23 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 163852726 Nonpathogen - hypothetical protein Mext_3311 1 None None None 163853615 Common - aminotransferase class I and II Mext_4218 196 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 163852834 Common - major facilitator superfamily MFS_1 Mext_3420 222 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163850524 Common - thioredoxin reductase Mext_1092 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 163852088 Common - hypothetical protein Mext_2669 115 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 163852033 Nonpathogen - heme exporter protein CcmD Mext_2613 1 None None None 163851349 Common - metallophosphoesterase Mext_1922 22 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 163850828 Common - sortase family protein Mext_1399 19 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 163851691 Common - protein of unknown function UPF0005 Mext_2268 133 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 163850925 Common - hypothetical protein Mext_1496 11 COG4461 LprI, Uncharacterized protein conserved in bacteria, putative lipoprotein Function unknown 163853408 Common - membrane protein involved in aromatic hydrocarbon degradation Mext_4009 72 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 163850845 Common - glycoside hydrolase family 24 Mext_1416 31 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 163853509 Nonpathogen - hypothetical protein Mext_4111 1 None None None 163851922 Common - OstA family protein Mext_2499 33 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 163851622 Nonpathogen - hypothetical protein Mext_2199 1 None None None 163851761 Common - hypothetical protein Mext_2338 6 None None None 163853109 Common - glycosyl transferase family 2 Mext_3705 163 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163850670 Common - GTP-binding protein LepA Mext_1240 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 163853982 Common - glycosyl transferase group 1 Mext_4586 93 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163854168 Common - L-fuculose-phosphate aldolase Mext_4772 155 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 163851649 Nonpathogen - hypothetical protein Mext_2226 1 None None None 163849948 Common - NAD-dependent epimerase/dehydratase Mext_0504 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163850383 Common - protein of unknown function DUF1078 domain protein Mext_0950 129 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 163853933 Common - protein of unknown function DUF985 Mext_4537 57 COG3542 COG3542, Uncharacterized conserved protein Function unknown 163852324 Nonpathogen - protein of unknown function UPF0153 Mext_2907 3 None None None 163850338 Common - hypothetical protein Mext_0905 17 None None None 163851665 Common - helix-turn-helix domain protein Mext_2242 56 COG1396 HipB, Predicted transcriptional regulators Transcription 163852805 Common - hypothetical protein Mext_3391 4 None None None 163852314 Common - cyclic nucleotide-binding Mext_2896 59 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163852788 Common - regulatory protein, FmdB family Mext_3374 20 None None None 163851840 Common - ATP-dependent Clp protease, ATP-binding subunit ClpX Mext_2417 223 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 163851184 Common - protein of unknown function DUF497 Mext_1757 33 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 163853754 Common - regulatory protein TetR Mext_4357 89 COG1309 AcrR, Transcriptional regulator Transcription 163852129 Common - malto-oligosyltrehalose trehalohydrolase Mext_2710 168 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 163853968 Common - peptidyl-prolyl cis-trans isomerase cyclophilin type Mext_4572 196 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 163853475 Common - Activator of Hsp90 ATPase 1 family protein Mext_4077 57 COG3832 COG3832, Uncharacterized conserved protein Function unknown 163851454 Common - putative ferredoxin-NAD reductase component Mext_2030 9 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 163850364 Nonpathogen - TadE family protein Mext_0931 10 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 163851038 Nonpathogen - hypothetical protein Mext_1611 1 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 163853746 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mext_4349 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 163850314 Nonpathogen - hypothetical protein Mext_0881 1 None None None 163853825 Nonpathogen - hypothetical protein Mext_4429 1 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 163851585 Common - ribosomal protein L3 Mext_2162 228 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 163853302 Common - Alcohol dehydrogenase zinc-binding domain protein Mext_3903 199 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 163851945 Common - glucose-6-phosphate 1-dehydrogenase Mext_2523 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 163852866 Common - membrane protein Mext_3452 20 COG0392 COG0392, Predicted integral membrane protein Function unknown 163850795 Nonpathogen - hypothetical protein Mext_1366 4 None None None 163851253 Common - formylmethanofuran dehydrogenase subunit A Mext_1826 35 COG1229 FwdA, Formylmethanofuran dehydrogenase subunit A Energy production and conversion 163850964 Common - hypothetical protein Mext_1537 28 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 163853374 Common - conserved hypothetical protein; putative alpha/beta hydrolase domain Mext_3975 86 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 163851443 Common - carbon starvation protein CstA Mext_2017 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 163854086 Nonpathogen - hypothetical protein Mext_4690 4 None None None 163849577 Common - major facilitator superfamily MFS_1 Mext_0121 81 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 163852574 Nonpathogen - protein of unknown function DUF1328 Mext_3158 3 None None None 163853730 Common - Surfeit locus 1 family protein Mext_4333 35 COG3346 COG3346, Uncharacterized conserved protein Function unknown 163850888 Common - ATPase associated with various cellular activities AAA_3 Mext_1459 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 163853250 Nonpathogen - hypothetical protein Mext_3850 1 None None None 163852603 Common - adenylyl cyclase class-3/4/guanylyl cyclase Mext_3188 82 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 163853875 Common - ribosomal L11 methyltransferase Mext_4479 165 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 163851882 Nonpathogen - hypothetical protein Mext_2459 1 None None None 163854220 Nonpathogen - hypothetical protein Mext_4824 1 None None None 163852296 Common - excinuclease ABC, C subunit Mext_2878 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 163852378 Common - chaperone protein DnaJ Mext_2961 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 163850251 Common - hypothetical protein Mext_0818 8 None None None 163850291 Common - NLP/P60 protein Mext_0858 97 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 163850013 Common - extracellular solute-binding protein family 1 Mext_0570 105 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 163851502 Common - hypothetical protein Mext_2078 15 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 163851509 Common - undecaprenyl diphosphate synthase Mext_2085 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 163849710 Nonpathogen - hypothetical protein Mext_0258 1 None None None 163852150 Nonpathogen - chlorophyllide reductase subunit Y Mext_2731 16 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 163852919 Common - response regulator receiver Mext_3506 213 COG4566 TtrR, Response regulator Signal transduction mechanisms 163851577 Common - phospholipase/Carboxylesterase Mext_2154 55 COG0400 COG0400, Predicted esterase General function prediction only 163853963 Common - DNA gyrase, A subunit Mext_4567 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 163851330 Nonpathogen - hypothetical protein Mext_1903 1 None None None 163850187 Common - Resolvase domain Mext_0747 99 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 163850983 Common - export-related chaperone CsaA Mext_1556 145 COG0073 ARC1, EMAP domain General function prediction only 163849928 Common - ribonuclease H Mext_0483 178 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 163849934 Common - UspA domain protein Mext_0489 41 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 163850270 Common - aldehyde oxidase and xanthine dehydrogenase molybdopterin binding Mext_0837 119 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 163849885 Common - Fe-S metabolism associated SufE Mext_0435 92 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 163852486 Common - S-adenosylmethionine--tRNA-ribosyltransferase-isomerase Mext_3069 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 163852623 Common - apolipoprotein N-acyltransferase Mext_3208 161 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 163852760 Common - ABC transporter related Mext_3345 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163853229 Common - HNS-dependent expression A Mext_3828 5 None None None 163853710 Nonpathogen - Capsular polysaccharide biosynthesis protein-like protein Mext_4313 5 COG4421 COG4421, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism 163853367 Nonpathogen - Propeptide PepSY amd peptidase M4 Mext_3968 1 None None None 163850443 Common - primosomal protein N' Mext_1010 210 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 163853182 Common - protein of unknown function DUF81 Mext_3780 116 COG0730 COG0730, Predicted permeases General function prediction only 163852402 Common - hypothetical protein Mext_2985 34 COG2267 PldB, Lysophospholipase Lipid metabolism 163853943 Common - Beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA/FabZ Mext_4547 184 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 163851266 Common - conserved hypothetical protein; putative signal peptide Mext_1839 19 None None None 163851437 Common - hypothetical protein Mext_2011 13 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 163852884 Common - lipid A biosynthesis acyltransferase Mext_3471 74 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 163850402 Common - oxidoreductase FAD/NAD(P)-binding domain protein Mext_0969 129 COG1017 Hmp, Hemoglobin-like flavoprotein Energy production and conversion 163851162 Common - alpha/beta hydrolase fold Mext_1735 95 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163850227 Nonpathogen - hypothetical protein Mext_0790 1 None None None 163851309 Common - response regulator receiver Mext_1882 58 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 163853215 Common - PAS sensor protein Mext_3813 114 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163853008 Common - succinate dehydrogenase, flavoprotein subunit Mext_3602 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 163850953 Common - Carbonate dehydratase Mext_1526 153 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 163854000 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Mext_4604 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 163853122 Nonpathogen - hypothetical protein Mext_3720 1 None None None 163850274 Nonpathogen - hypothetical protein Mext_0841 1 None None None 163852184 Common - surface antigen (D15) Mext_2765 145 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 163852493 Nonpathogen - hypothetical protein Mext_3076 5 None None None 163854204 Nonpathogen - hypothetical protein Mext_4808 9 None None None 163853979 Nonpathogen - polysaccharide biosynthesis protein Mext_4583 6 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 163853701 Common - folate-binding protein YgfZ Mext_4304 111 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 163853538 Common - von Willebrand factor type A Mext_4141 10 None None None 163850407 Nonpathogen - hypothetical protein Mext_0974 1 None None None 163852685 Common - response regulator receiver Mext_3270 163 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163852220 Common - regulatory protein AsnC/Lrp family Mext_2801 121 COG1522 Lrp, Transcriptional regulators Transcription 163852709 Common - Carbamoyltransferase Mext_3294 52 COG2192 COG2192, Predicted carbamoyl transferase, NodU family Posttranslational modification, protein turnover, chaperones 163852262 Common - WD-40 repeat protein Mext_2844 90 COG2319 COG2319, FOG: WD40 repeat General function prediction only 163851398 Common - Na+ dependent nucleoside transporter domain protein Mext_1971 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 163851368 Common - squalene synthase HpnC Mext_1941 81 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 163853858 Common - RNA polymerase sigma factor, sigma-70 family Mext_4462 165 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 163851523 Nonpathogen - hypothetical protein Mext_2100 4 None None None 163853059 Common - AMP-dependent synthetase and ligase Mext_3653 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163853385 Common - porin Mext_3986 14 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 163853062 Common - metal dependent phophohydrolase Mext_3656 119 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 163851717 Nonpathogen - hypothetical protein Mext_2294 6 None None None 163850146 Common - penicillin-binding protein, 1A family Mext_0706 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 163851317 Nonpathogen - hypothetical protein Mext_1890 1 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 163851425 Nonpathogen - hypothetical protein Mext_1998 1 None None None 163853498 Common - carbonic anhydrase Mext_4100 134 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 163850386 Common - hypothetical protein Mext_0953 31 COG5373 COG5373, Predicted membrane protein Function unknown 163853052 Nonpathogen - protein of unknown function DUF1332 Mext_3646 1 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 163850588 Common - LysR substrate-binding Mext_1158 138 COG0583 LysR, Transcriptional regulator Transcription 163852655 Nonpathogen - protein of unknown function UPF0057 Mext_3240 1 COG0401 COG0401, Uncharacterized homolog of Blt101 Function unknown 163850457 Common - protein of unknown function DUF1311 Mext_1024 12 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 163851680 Common - transglutaminase family protein cysteine peptidase BTLCP Mext_2257 19 COG3672 COG3672, Predicted periplasmic protein Function unknown 163854124 Common - Malonyl-CoA decarboxylase Mext_4728 29 None None None 163849737 Common - ketol-acid reductoisomerase Mext_0285 214 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 163849488 Common - ROSMUCR transcriptional regulator Mext_0032 29 COG4957 COG4957, Predicted transcriptional regulator Transcription 163850202 Common - transposase IS4 family protein Mext_0762 62 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 163849905 Nonpathogen - hypothetical protein Mext_0456 1 None None None 163852769 Common - diguanylate cyclase Mext_3354 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163851276 Nonpathogen - hypothetical protein Mext_1849 1 None None None 163853046 Common - hypothetical protein Mext_3640 14 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163853836 Common - double-strand break repair helicase AddA Mext_4440 189 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 163854040 Common - protein of unknown function DUF820 Mext_4644 27 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 163852158 Common - type I secretion system ATPase Mext_2739 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 163854049 Common - glutamate--cysteine ligase GCS2 Mext_4653 70 COG2170 COG2170, Uncharacterized conserved protein Function unknown 163852605 Common - Lytic transglycosylase catalytic Mext_3190 158 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 163851721 Common - ribose 5-phosphate isomerase Mext_2298 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 163849501 Common - helix-turn-helix- domain containing protein AraC type Mext_0045 56 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 163849911 Common - sodium:dicarboxylate symporter Mext_0462 159 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 163852675 Nonpathogen - conserved protein CoxF Mext_3260 6 None None None 163854227 Common - OmpA/MotB domain protein Mext_4831 110 COG1360 MotB, Flagellar motor protein Cell motility and secretion 163850908 Common - GCN5-related N-acetyltransferase Mext_1479 17 None None None 163853093 Common - transposase IS116/IS110/IS902 Mext_3689 22 None None None 163854065 Common - chemotaxis sensory transducer Mext_4669 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163851355 Common - transglutaminase family protein cysteine peptidase BTLCP Mext_1928 19 COG3672 COG3672, Predicted periplasmic protein Function unknown 163853235 Common - protein of unknown function DUF81 Mext_3835 43 COG0730 COG0730, Predicted permeases General function prediction only 163850868 Common - cobaltochelatase, CobN subunit Mext_1439 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 163851572 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Mext_2149 119 COG0546 Gph, Predicted phosphatases General function prediction only 163851671 Common - NADH:flavin oxidoreductase/NADH oxidase Mext_2248 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 163852160 Common - ribosomal protein L36 Mext_2741 61 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 163854212 Common - light-independent protochlorophyllide reductase, N subunit Mext_4816 29 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 163849780 Common - ATP-binding region ATPase domain protein Mext_0328 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163851160 Common - ABC transporter related Mext_1733 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163853790 Common - helicase domain protein Mext_4394 65 COG4581 COG4581, Superfamily II RNA helicase DNA replication, recombination, and repair 163850020 Nonpathogen - Cupin 2 conserved barrel domain protein Mext_0577 3 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 163850445 Nonpathogen - putative exported protein of unknown function Mext_1012 4 None None None 163850806 Common - Peptidoglycan-binding domain 1 protein Mext_1377 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 163854275 Nonpathogen - hypothetical protein Mext_4879 1 None None None 163852209 Common - dihydrolipoamide dehydrogenase Mext_2790 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 163853286 Common - PDZ/DHR/GLGF domain protein Mext_3887 207 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 163853247 Common - Methyltransferase type 12 Mext_3847 21 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 163852841 Nonpathogen - hypothetical protein Mext_3427 1 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163852516 Nonpathogen - hypothetical protein Mext_3100 1 None None None 163852502 Common - catalase Mext_3086 19 None None None 163849745 Common - regulatory protein ArsR Mext_0293 30 COG4189 COG4189, Predicted transcriptional regulator Transcription 163851321 Common - PAS sensor protein Mext_1894 149 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163849582 Common - Alpha/beta hydrolase fold-3 domain protein Mext_0126 130 COG0657 Aes, Esterase/lipase Lipid metabolism 163850018 Common - amine oxidase Mext_0575 32 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 163850488 Common - protein of unknown function DUF182 Mext_1055 53 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 163852631 Common - metallophosphoesterase Mext_3216 20 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 163851723 Nonpathogen - O-antigen polymerase Mext_2300 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 163852965 Common - Nucleotidyl transferase Mext_3557 227 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 163850409 Nonpathogen - hypothetical protein Mext_0976 6 None None None 163852507 Common - aminotransferase class I and II Mext_3091 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 163854139 Common - hypothetical protein Mext_4743 124 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 163853647 Nonpathogen - hypothetical protein Mext_4250 1 None None None 163849691 Common - hypothetical protein Mext_0238 3 None None None 163851607 Common - ribosomal protein S5 Mext_2184 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 163852469 Common - hypothetical protein Mext_3052 19 COG3334 COG3334, Uncharacterized conserved protein Function unknown 163852753 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Mext_3338 44 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163853957 Common - LamB/YcsF family protein Mext_4561 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 163854039 Nonpathogen - hypothetical protein Mext_4643 1 None None None 163849895 Common - protein of unknown function DUF1003 Mext_0445 45 COG4420 COG4420, Predicted membrane protein Function unknown 163854015 Common - NAD-dependent epimerase/dehydratase Mext_4619 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163850041 Common - phosphoribosylformylglycinamidine synthase I Mext_0599 230 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 163851412 Common - hypothetical protein Mext_1985 21 None None None 163853060 Common - MscS Mechanosensitive ion channel Mext_3654 42 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 163853665 Common - putative alpha/beta hydrolase fold Mext_4268 21 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163854042 Common - peptidylprolyl isomerase FKBP-type Mext_4646 153 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 163849822 Common - 2-deoxycytidine 5-triphosphate deaminase Mext_0372 27 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 163850369 Common - ribonuclease H Mext_0936 174 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 163851427 Common - Guanylate kinase Mext_2000 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 163854175 Common - Cobyrinic acid ac-diamide synthase Mext_4779 198 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 163854037 Common - S-adenosyl-methyltransferase MraW Mext_4641 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 163850239 Common - DNA methylase N-4/N-6 domain protein Mext_0806 108 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 163850939 Common - VWA containing CoxE family protein Mext_1510 25 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 163849876 Common - short-chain dehydrogenase/reductase SDR Mext_0426 208 COG0623 FabI, Enoyl- acyl-carrier-protein 163850759 Common - cytochrome P450 Mext_1330 90 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 163851525 Common - TonB-dependent receptor plug Mext_2102 95 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 163851235 Common - ABC transporter related Mext_1808 247 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163850168 Common - acyltransferase 3 Mext_0728 59 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 163852282 Common - protein of unknown function DUF214 Mext_2864 34 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 163850134 Common - hypothetical protein Mext_0694 7 None None None 163853575 Common - Alpha/beta hydrolase fold-3 domain protein Mext_4178 127 COG0657 Aes, Esterase/lipase Lipid metabolism 163852294 Common - molybdopterin converting factor, subunit 1 Mext_2876 50 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 163850866 Common - Precorrin-8X methylmutase Mext_1437 118 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 163852554 Common - glycogen debranching enzyme GlgX Mext_3138 162 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 163853716 Common - cation diffusion facilitator family transporter Mext_4319 167 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 163850855 Common - hypothetical protein Mext_1426 7 None None None 163849791 Common - Prephenate dehydratase Mext_0339 212 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 163851782 Nonpathogen - hypothetical protein Mext_2359 1 None None None 163853912 Common - methyltransferase FkbM family Mext_4516 63 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 163853290 Common - excinuclease ABC, A subunit Mext_3891 242 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 163854138 Common - Peptidoglycan-binding LysM Mext_4742 41 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 163851895 Common - Deoxyribonuclease V Mext_2472 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 163851562 Common - 2-dehydropantoate 2-reductase Mext_2139 90 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 163853294 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Mext_3895 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163849777 Common - Exonuclease RNase T and DNA polymerase III Mext_0325 136 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 163853470 Common - secretion protein HlyD family protein Mext_4072 114 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163850589 Common - RNA polymerase sigma factor, sigma-70 family Mext_1159 163 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 163849617 Common - integrase family protein Mext_0163 145 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163851704 Nonpathogen - hypothetical protein Mext_2281 1 None None None 163851313 Nonpathogen - hypothetical protein Mext_1886 1 None None None 163853919 Nonpathogen - hypothetical protein Mext_4523 1 None None None 163852252 Common - ROSMUCR transcriptional regulator Mext_2834 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 163853787 Common - hypothetical protein Mext_4391 4 None None None 163853457 Common - DoxX family protein Mext_4059 54 COG2259 COG2259, Predicted membrane protein Function unknown 163850752 Common - hypothetical protein Mext_1323 3 None None None 163852412 Nonpathogen - hypothetical protein Mext_2995 1 None None None 163852545 Common - major facilitator superfamily MFS_1 Mext_3129 187 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163850356 Common - FAD linked oxidase domain protein Mext_0923 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 163852460 Nonpathogen - hypothetical protein Mext_3043 4 None None None 163850245 Nonpathogen - hypothetical protein Mext_0812 2 None None None 163849867 Nonpathogen - hypothetical protein Mext_0417 1 None None None 163852420 Common - lysine 2,3-aminomutase YodO family protein Mext_3003 125 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 163853621 Common - manganese containing catalase Mext_4224 44 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 163850180 Common - chaperonin Cpn10 Mext_0740 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 163850718 Common - Carbon-monoxide dehydrogenase (acceptor) Mext_1289 109 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 163850434 Common - RNA polymerase sigma factor RpoH Mext_1001 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 163850283 Common - NAD-dependent epimerase/dehydratase Mext_0850 134 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163849527 Nonpathogen - hypothetical protein Mext_0071 1 None None None 163849765 Common - protein of unknown function DUF541 Mext_0313 64 COG2968 COG2968, Uncharacterized conserved protein Function unknown 163854148 Common - Methyltransferase type 11 Mext_4752 172 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163851714 Common - diguanylate cyclase Mext_2291 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163852272 Nonpathogen - PRC-barrel domain protein Mext_2854 3 COG1873 COG1873, Uncharacterized conserved protein Function unknown 163853868 Common - hypothetical protein Mext_4472 57 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 163853543 Common - ATPase associated with various cellular activities AAA_3 Mext_4146 173 COG0714 COG0714, MoxR-like ATPases General function prediction only 163851486 Common - phosphoribosylglycinamide formyltransferase Mext_2062 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 163852728 Common - dihydroorotase, multifunctional complex type Mext_3313 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 163853931 Nonpathogen - hypothetical protein Mext_4535 1 None None None 163852341 Common - TonB-dependent receptor Mext_2924 85 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 163852563 Common - chemotaxis sensory transducer Mext_3147 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163852075 Common - phosphoserine phosphatase SerB Mext_2655 156 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 163849806 Nonpathogen - hypothetical protein Mext_0356 2 None None None 163849832 Nonpathogen - hypothetical protein Mext_0382 8 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 163853119 Common - UDP-N-acetylglucosamine 2-epimerase Mext_3716 154 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 163852510 Common - sodium/hydrogen exchanger Mext_3094 186 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 163851136 Nonpathogen - hypothetical protein Mext_1709 1 None None None 163850630 Common - urea ABC transporter, urea binding protein Mext_1200 134 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 163853961 Common - MRP protein-like protein Mext_4565 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 163850555 Common - hypothetical protein Mext_1123 18 None None None 163853110 Nonpathogen - hypothetical protein Mext_3706 1 None None None 163849492 Common - Kojibiose phosphorylase Mext_0036 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 163853694 Common - short-chain dehydrogenase/reductase SDR Mext_4297 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163853209 Nonpathogen - hypothetical protein Mext_3807 3 None None None 163852305 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I Mext_2887 194 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 163851817 Common - dTDP-4-dehydrorhamnose reductase Mext_2394 163 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 163853618 Common - GCN5-related N-acetyltransferase Mext_4221 49 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 163853267 Common - diguanylate cyclase Mext_3867 182 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163849900 Common - rare lipoprotein A Mext_0451 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 163850861 Common - phage prohead protease, HK97 family Mext_1432 43 COG3740 COG3740, Phage head maturation protease General function prediction only 163854163 Common - metallophosphoesterase Mext_4767 91 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 163850306 Common - methionine-R-sulfoxide reductase Mext_0873 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 163853678 Common - thiol:disulfide interchange protein, putative Mext_4281 76 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 163852734 Common - Holliday junction resolvase YqgF Mext_3319 170 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 163854055 Nonpathogen - integral membrane protein-like protein Mext_4659 3 COG5463 COG5463, Predicted integral membrane protein Function unknown 163851764 Common - pyrimidine 5'-nucleotidase Mext_2341 46 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 163849712 Common - hypothetical protein Mext_0260 16 COG4923 COG4923, Uncharacterized conserved protein Function unknown 163850461 Common - heat shock protein Hsp90 Mext_1028 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 163851947 Nonpathogen - hypothetical protein Mext_2525 1 None None None 163853871 Common - N-acetyl-gamma-glutamyl-phosphate reductase Mext_4475 212 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 163849699 Nonpathogen - hypothetical protein Mext_0246 11 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 163850798 Common - Cellulase Mext_1369 35 COG3405 CelA, Endoglucanase Y Carbohydrate transport and metabolism 163852436 Common - urease, gamma subunit Mext_3019 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 163852818 Common - NADPH-dependent FMN reductase Mext_3404 59 COG0431 COG0431, Predicted flavoprotein General function prediction only 163851386 Common - protein of unknown function DUF465 Mext_1959 16 COG5570 COG5570, Uncharacterized small protein Function unknown 163853144 Common - YbaK/prolyl-tRNA synthetase associated region Mext_3742 30 COG3760 COG3760, Uncharacterized conserved protein Function unknown 163854071 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Mext_4675 185 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 163851360 Common - ABC transporter related Mext_1933 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 163854241 Common - response regulator receiver Mext_4845 146 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 163850771 Common - hypothetical protein Mext_1342 27 COG4339 COG4339, Uncharacterized protein conserved in bacteria Function unknown 163852499 Common - adenylate cyclase Mext_3082 45 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 163850666 Common - HPr kinase Mext_1236 16 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 163850830 Common - Phosphoglycerate mutase Mext_1401 7 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 163853175 Common - ATP-binding region ATPase domain protein Mext_3773 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163853609 Common - glycosyl transferase family 2 Mext_4212 9 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163851281 Common - hypothetical protein Mext_1854 8 COG5126 FRQ1, Ca2+-binding protein (EF-Hand superfamily) Signal transduction mechanisms / Cytoskeleton / Cell division and chromosome partitioning / General function prediction only 163849678 Common - cytochrome c oxidase subunit III Mext_0224 124 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 163851516 Common - Transketolase central region Mext_2092 226 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 163853597 Common - aminotransferase class V Mext_4200 160 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 163849663 Common - short-chain dehydrogenase/reductase SDR Mext_0209 236 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 163850998 Common - hypothetical protein Mext_1571 9 None None None 163851980 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_2558 86 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163850154 Common - Ceramide glucosyltransferase Mext_0714 26 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163850961 Common - Allophanate hydrolase subunit 1 Mext_1534 106 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 163851230 Common - protein of unknown function DUF1003 Mext_1803 14 COG4420 COG4420, Predicted membrane protein Function unknown 163851237 Common - hypothetical protein Mext_1810 12 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 163852441 Common - amidohydrolase Mext_3024 167 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 163851288 Common - DNA polymerase III, subunits gamma and tau Mext_1861 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 163852388 Common - protein of unknown function DUF374 Mext_2971 42 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 163850821 Nonpathogen - hypothetical protein Mext_1392 1 None None None 163851224 Common - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Mext_1797 8 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 163853897 Common - transketolase Mext_4501 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 163852247 Common - protein of unknown function DUF305 Mext_2829 45 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 163852980 Nonpathogen - hypothetical protein Mext_3572 1 None None None 163851152 Nonpathogen - hypothetical protein Mext_1725 1 None None None 163851305 Nonpathogen - hypothetical protein Mext_1878 1 None None None 163850399 Common - response regulator receiver Mext_0966 224 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 163853023 Nonpathogen - hypothetical protein Mext_3617 1 None None None 163849702 Common - Radical SAM domain protein Mext_0249 68 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 163849682 Common - RNA polymerase sigma factor, sigma-70 family Mext_0228 147 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 163854268 Nonpathogen - hypothetical protein Mext_4872 1 None None None 163851792 Common - fructose-bisphosphate aldolase, class II, Calvin cycle subtype Mext_2369 169 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 163853069 Common - Alkanesulfonate monooxygenase Mext_3663 91 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 163849848 Common - protein of unknown function DUF6 transmembrane Mext_0398 53 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 163852381 Common - thymidine phosphorylase Mext_2964 123 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 163853707 Common - superoxide dismutase copper/zinc binding Mext_4310 85 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 163852126 Common - cobalamin synthesis protein P47K Mext_2707 129 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 163853317 Common - hemimethylated DNA binding protein Mext_3918 38 COG3785 COG3785, Uncharacterized conserved protein Function unknown 163850267 Common - peptidase M20 Mext_0834 137 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 163854280 Nonpathogen - hypothetical protein Mext_4884 1 None None None 163853681 Common - ATP-dependent helicase HrpB Mext_4284 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 163849759 Common - competence protein F Mext_0307 151 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 163851057 Common - phenylalanyl-tRNA synthetase, beta subunit Mext_1630 225 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 163850649 Common - cobalamin synthesis protein P47K Mext_1219 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 163854115 Common - GcrA cell cycle regulator Mext_4719 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 163849804 Nonpathogen - hypothetical protein Mext_0354 1 None None None 163849624 Common - ROSMUCR transcriptional regulator Mext_0170 31 COG4957 COG4957, Predicted transcriptional regulator Transcription 163851192 Common - UspA domain protein Mext_1765 34 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 163849975 Nonpathogen - hypothetical protein Mext_0532 1 None None None 163851123 Common - conserved hypothetical protein; putative signal peptide Mext_1696 7 COG3248 Tsx, Nucleoside-binding outer membrane protein Cell envelope biogenesis, outer membrane 163852744 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_3329 87 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163850340 Common - conserved hypothetical transmembrane signal peptide protein Mext_0907 50 COG3577 COG3577, Predicted aspartyl protease General function prediction only 163850967 Common - hypothetical protein Mext_1540 10 None None None 163851143 Common - 2OG-Fe(II) oxygenase Mext_1716 55 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 163851673 Nonpathogen - hypothetical protein Mext_2250 2 None None None 163850260 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase Mext_0827 206 COG0281 SfcA, Malic enzyme Energy production and conversion 163852593 Common - protein of unknown function DUF1159 Mext_3178 26 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 163851546 Nonpathogen - hypothetical protein Mext_2123 3 None None None 163851985 Common - protein of unknown function DUF485 Mext_2563 45 COG3162 COG3162, Predicted membrane protein Function unknown 163851064 Common - hypothetical protein Mext_1637 5 None None None 163851822 Common - peptidase, M50 family Mext_2399 29 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163850611 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mext_1181 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 163851212 Nonpathogen - hypothetical protein Mext_1785 1 None None None 163854150 Common - secretion protein HlyD family protein Mext_4754 156 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163853906 Common - Rhodanese domain protein Mext_4510 46 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 163853503 Common - Sua5/YciO/YrdC/YwlC family protein Mext_4105 226 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 163850945 Common - Uracil-DNA glycosylase superfamily Mext_1518 58 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 163852100 Common - Methyltransferase type 11 Mext_2681 3 COG2851 CitM, H+/citrate symporter Energy production and conversion 163851012 Common - Cobyrinic acid ac-diamide synthase Mext_1585 209 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 163850481 Common - DNA polymerase III, alpha subunit Mext_1048 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 163852778 Nonpathogen - signal transduction histidine kinase Mext_3364 4 None None None 163852653 Common - protein of unknown function UPF0047 Mext_3238 139 COG0432 COG0432, Uncharacterized conserved protein Function unknown 163851477 Common - fatty acid/phospholipid synthesis protein PlsX Mext_2053 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 163853088 Common - glycosyl transferase group 1 Mext_3684 35 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 163849849 Common - heat-inducible transcription repressor HrcA Mext_0399 148 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 163851915 Common - diguanylate cyclase Mext_2492 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 163853838 Common - thioredoxin Mext_4442 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 163850392 Common - ubiquinone biosynthesis O-methyltransferase Mext_0959 131 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 163852893 Common - cyclic nucleotide-binding Mext_3480 78 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163853672 Nonpathogen - hypothetical protein Mext_4275 1 None None None 163854198 Common - ATP-dependent Clp protease, ATP-binding subunit clpA Mext_4802 232 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 163850932 Common - putative DNA-binding protein Mext_1503 39 COG2944 COG2944, Predicted transcriptional regulator Transcription 163850786 Common - cyclic nucleotide-binding Mext_1357 139 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163851903 Common - type II and III secretion system protein Mext_2480 137 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 163853998 Common - aminotransferase class IV Mext_4602 169 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 163852485 Common - monooxygenase FAD-binding Mext_3068 130 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 163851618 Common - diguanylate cyclase Mext_2195 176 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163850068 Common - flagellar basal body-associated protein FliL Mext_0626 11 None None None 163852110 Common - Cu(I)-responsive transcriptional regulator Mext_2691 142 COG0789 SoxR, Predicted transcriptional regulators Transcription 163850106 Common - MATE efflux family protein Mext_0664 120 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 163850061 Common - flagellar basal-body rod protein FlgC Mext_0619 118 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 163851914 Common - major facilitator superfamily MFS_1 Mext_2491 19 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163852581 Nonpathogen - hypothetical protein Mext_3165 1 None None None 163852996 Nonpathogen - hypothetical protein Mext_3590 1 None None None 163850347 Common - aldehyde oxidase and xanthine dehydrogenase molybdopterin binding Mext_0914 103 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 163850976 Common - glycogen debranching enzyme GlgX Mext_1549 139 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 163851503 Common - hypothetical protein Mext_2079 2 None None None 163853488 Nonpathogen - putative flagellar assembly protein FliH Mext_4090 7 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 163852946 Common - NLP/P60 protein Mext_3535 5 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 163849750 Common - LAO/AO transport system ATPase Mext_0298 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 163850933 Common - DSBA oxidoreductase Mext_1504 52 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 163851779 Common - lipid A ABC exporter family, fused ATPase and inner membrane subunits Mext_2356 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 163852942 Common - Integrase catalytic region Mext_3531 128 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 163850496 Common - Exopolysaccharide synthesis ExoD Mext_1063 23 COG3932 COG3932, Uncharacterized ABC-type transport system, permease components General function prediction only 163851492 Common - Ppx/GppA phosphatase Mext_2068 172 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 163850591 Common - type I secretion system ATPase Mext_1161 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 163852537 Common - Threonine aldolase Mext_3121 110 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 163852214 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_2795 25 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163851499 Common - uridylate kinase Mext_2075 244 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 163852641 Common - extracellular solute-binding protein family 3 Mext_3226 99 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 163851593 Common - ribosomal protein L29 Mext_2170 163 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 163852300 Common - porin Mext_2882 14 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 163853830 Common - AMP-dependent synthetase and ligase Mext_4434 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 163850113 Common - Coproporphyrinogen oxidase Mext_0673 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 163850418 Nonpathogen - hypothetical protein Mext_0985 2 None None None 163852371 Common - DNA repair protein RecN Mext_2954 196 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 163852490 Nonpathogen - hypothetical protein Mext_3073 2 None None None 163853764 Common - amine oxidase Mext_4367 19 COG1231 COG1231, Monoamine oxidase Amino acid transport and metabolism 163849959 Common - response regulator receiver Mext_0516 215 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163850519 Common - pseudoazurin Mext_1087 26 COG3794 PetE, Plastocyanin Energy production and conversion 163853012 Common - conserved hypothetical proteinn Mext_3606 19 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 163852878 Common - Lytic transglycosylase catalytic Mext_3465 21 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 163850149 Common - protein of unknown function UPF0066 Mext_0709 96 COG1720 COG1720, Uncharacterized conserved protein Function unknown 163854125 Nonpathogen - CsbD family protein Mext_4729 6 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 163854209 Common - light-independent protochlorophyllide reductase, iron-sulfur ATP-binding protein Mext_4813 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 163850814 Common - GntR domain protein Mext_1385 127 COG1802 GntR, Transcriptional regulators Transcription 163849631 Common - Phosphoribosylanthranilate isomerase Mext_0177 172 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 163854030 Common - sodium/hydrogen exchanger Mext_4634 180 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 163851103 Nonpathogen - DoxX family protein Mext_1676 1 None None None 163849942 Common - hypothetical protein Mext_0498 4 None None None 163850214 Nonpathogen - hypothetical protein Mext_0776 1 None None None 163851805 Common - NUDIX hydrolase Mext_2382 45 None None None 163853356 Common - NAD-dependent epimerase/dehydratase Mext_3957 16 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163851029 Nonpathogen - hypothetical protein Mext_1602 1 None None None 163851172 Common - hydroxyisourate hydrolase Mext_1745 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 163853422 Nonpathogen - hypothetical protein Mext_4024 1 None None None 163853630 Common - stationary-phase survival protein SurE Mext_4233 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 163852976 Common - glycosyl transferase group 1 Mext_3568 4 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163853669 Common - extracellular solute-binding protein family 5 Mext_4272 206 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 163853696 Common - NUDIX hydrolase Mext_4299 124 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 163853153 Common - aminoglycoside phosphotransferase Mext_3751 6 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 163853416 Common - DNA-directed RNA polymerase, beta' subunit Mext_4018 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 163853995 Common - flavin reductase domain protein FMN-binding Mext_4599 90 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 163852528 Nonpathogen - hypothetical protein Mext_3112 1 None None None 163850760 Common - diguanylate cyclase Mext_1331 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163853771 Nonpathogen - hypothetical protein Mext_4374 1 None None None 163852049 Nonpathogen - hypothetical protein Mext_2629 1 None None None 163853326 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Mext_3927 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 163850099 Nonpathogen - hypothetical protein Mext_0657 1 None None None 163851952 Common - monofunctional biosynthetic peptidoglycan transglycosylase Mext_2530 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 163851075 Common - dihydrolipoamide dehydrogenase Mext_1648 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 163853807 Nonpathogen - hypothetical protein Mext_4411 1 None None None 163852811 Common - Sporulation domain protein Mext_3397 12 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 163850695 Common - GTP-binding protein TypA Mext_1265 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 163850426 Common - Ornithine decarboxylase Mext_0993 78 COG1982 LdcC, Arginine/lysine/ornithine decarboxylases Amino acid transport and metabolism 163853950 Common - Cupin 2 conserved barrel domain protein Mext_4554 27 COG4101 COG4101, Predicted mannose-6-phosphate isomerase Carbohydrate transport and metabolism 163851478 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III Mext_2054 223 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 163849701 Nonpathogen - glycosyl transferase group 1 Mext_0248 12 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163849548 Common - hypothetical protein Mext_0092 12 COG3474 COG3474, Cytochrome c2 Energy production and conversion 163850459 Nonpathogen - hypothetical protein Mext_1026 1 None None None 163852936 Nonpathogen - hypothetical protein Mext_3525 1 None None None 163854184 Common - phosphate transporter Mext_4788 149 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 163853536 Common - 40-residue YVTN family beta-propeller repeat protein Mext_4139 91 COG3391 COG3391, Uncharacterized conserved protein Function unknown 163851168 Common - allantoin catabolism protein Mext_1741 33 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 163853341 Common - ribosomal protein S6 Mext_3942 201 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 163850727 Common - DEAD/DEAH box helicase domain protein Mext_1298 215 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 163850629 Common - Urease accessory protein UreD Mext_1199 22 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 163849722 Nonpathogen - hypothetical protein Mext_0270 1 None None None 163853180 Common - response regulator receiver Mext_3778 39 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163849638 Nonpathogen - hypothetical protein Mext_0184 1 None None None 163853006 Common - succinate dehydrogenase, cytochrome b556 subunit Mext_3600 57 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 163850140 Common - PAS sensor protein Mext_0700 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163854043 Nonpathogen - hypothetical protein Mext_4647 1 None None None 163851102 Common - luciferase family protein Mext_1675 49 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 163851783 Common - OmpA/MotB domain protein Mext_2360 144 COG1360 MotB, Flagellar motor protein Cell motility and secretion 163849507 Common - GCN5-related N-acetyltransferase Mext_0051 107 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 163850193 Common - hypothetical protein Mext_0753 7 None None None 163852771 Common - transcription elongation factor GreA/GreB domain protein Mext_3357 75 COG0782 GreA, Transcription elongation factor Transcription 163851807 Common - hypothetical protein Mext_2384 100 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163850385 Common - hypothetical protein Mext_0952 19 None None None 163853749 Common - protein of unknown function DUF81 Mext_4352 26 None None None 163850205 Nonpathogen - HNH endonuclease Mext_0765 3 None None None 163852683 Common - beta-lactamase domain protein Mext_3268 89 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 163850272 Common - protein of unknown function DUF6 transmembrane Mext_0839 37 COG2510 COG2510, Predicted membrane protein Function unknown 163849549 Common - hypothetical protein Mext_0093 15 COG3336 COG3336, Predicted membrane protein Function unknown 163850924 Common - hypothetical protein Mext_1495 97 COG1981 COG1981, Predicted membrane protein Function unknown 163851876 Common - NADP oxidoreductase coenzyme F420-dependent Mext_2453 35 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 163850729 Common - urea transporter Mext_1300 19 COG4413 Utp, Urea transporter Amino acid transport and metabolism 163850104 Common - translation initiation factor, aIF-2BI family Mext_0662 130 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 163850959 Common - Protein-glutamate methylesterase Mext_1532 214 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 163852483 Nonpathogen - hypothetical protein Mext_3066 1 None None None 163851337 Common - arsenate reductase Mext_1910 106 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 163849575 Common - integrase family protein Mext_0119 59 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 163852156 Common - photosynthetic reaction center, M subunit Mext_2737 21 None None None 163851091 Common - Hemolysin-type calcium-binding region Mext_1664 51 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 163850951 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Mext_1524 154 COG0756 Dut, dUTPase Nucleotide transport and metabolism 163852955 Common - transposase IS3/IS911 family protein Mext_3547 42 None None None 163854096 Common - integrase, catalytic region Mext_4700 11 None None None 163851065 Common - recombination protein RecR Mext_1638 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 163850482 Common - hypothetical protein Mext_1049 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 163851187 Common - homoserine O-acetyltransferase Mext_1760 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 163850655 Common - queuosine biosynthesis protein QueD Mext_1225 134 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 163851889 Common - oligopeptide transporter, OPT family Mext_2466 41 COG1297 COG1297, Predicted membrane protein Function unknown 163853689 Common - enoyl-acyl carrier protein reductase Mext_4292 214 COG0623 FabI, Enoyl- acyl-carrier-protein 163850240 Nonpathogen - hypothetical protein Mext_0807 1 None None None 163853334 Common - electron transport protein SCO1/SenC Mext_3935 103 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 163850184 Nonpathogen - hypothetical protein Mext_0744 1 None None None 163852628 Nonpathogen - diacylglycerol kinase Mext_3213 1 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 163853361 Common - polar amino acid ABC transporter, inner membrane subunit Mext_3962 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 163853935 Common - protein of unknown function DUF606 Mext_4539 48 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 163853547 Common - PQQ-dependent dehydrogenase, methanol/ethanol family Mext_4150 59 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 163850820 Common - Pyridoxal-5'-phosphate-dependent protein beta subunit Mext_1391 218 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 163849538 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_0082 28 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163852621 Common - protein of unknown function UPF0054 Mext_3206 151 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 163850847 Common - gene transfer agent (GTA) orfg15, like protein Mext_1418 24 None None None 163851180 Nonpathogen - hypothetical protein Mext_1753 1 None None None 163853203 Common - Carbonate dehydratase Mext_3801 149 COG0583 LysR, Transcriptional regulator Transcription 163850252 Common - flagellar biosynthesis protein FlhA Mext_0819 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 163851487 Common - phosphoribosylformylglycinamidine cyclo-ligase Mext_2063 229 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 163850607 Common - cyclic nucleotide-binding Mext_1177 31 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163853355 Common - sodium:dicarboxylate symporter Mext_3956 158 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 163849863 Common - Peptidyl-dipeptidase Dcp Mext_0413 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 163851294 Nonpathogen - hypothetical protein Mext_1867 1 None None None 163854089 Common - hypothetical protein Mext_4693 12 None None None 163853680 Nonpathogen - hypothetical protein Mext_4283 1 None None None 163853890 Common - nitrate ABC transporter, ATPase subunits C and D Mext_4494 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163853068 Common - penicillin-binding protein, 1A family Mext_3662 201 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 163849855 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Mext_0405 210 COG0313 COG0313, Predicted methyltransferases General function prediction only 163851973 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Mext_2551 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 163849821 Nonpathogen - hypothetical protein Mext_0371 1 None None None 163852700 Common - PRC-barrel domain protein Mext_3285 36 None None None 163853873 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Mext_4477 145 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 163854171 Common - PepSY-associated TM helix domain protein Mext_4775 39 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 163852376 Nonpathogen - hypothetical protein Mext_2959 1 None None None 163850289 Nonpathogen - hypothetical protein Mext_0856 1 None None None 163851880 Nonpathogen - hypothetical protein Mext_2457 13 COG3378 COG3378, Predicted ATPase General function prediction only 163849812 Common - DNA-directed DNA polymerase Mext_0362 23 None None None 163852082 Common - protein of unknown function DUF1321 Mext_2662 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 163854118 Common - precorrin-6x reductase Mext_4722 73 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 163851960 Common - Capsule polysaccharide biosynthesis protein Mext_2538 30 COG3562 KpsS, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 163853809 Common - ribosomal protein L27 Mext_4413 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 163851920 Common - 3'-5' exonuclease Mext_2497 115 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 163849838 Nonpathogen - formate dehydrogenase region TAT target Mext_0388 5 None None None 163851426 Common - domain of unknown function DUF1732 Mext_1999 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 163850366 Nonpathogen - hypothetical protein Mext_0933 5 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 163849994 Common - Fmu (Sun) domain protein Mext_0551 206 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 163853884 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Mext_4488 51 COG3576 COG3576, Predicted flavin-nucleotide-binding protein structurally related to pyridoxine 5'-phosphate oxidase General function prediction only 163852326 Nonpathogen - hypothetical protein Mext_2909 1 None None None 163852652 Common - ATP dependent DNA ligase Mext_3237 102 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 163853103 Nonpathogen - hypothetical protein Mext_3699 1 None None None 163851259 Common - alpha-L-glutamate ligase, RimK family Mext_1832 96 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 163850505 Common - proton-translocating NADH-quinone oxidoreductase, chain M Mext_1073 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 163850819 Nonpathogen - hypothetical protein Mext_1390 1 None None None 163851829 Common - Radical SAM domain protein Mext_2406 83 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 163852910 Nonpathogen - hypothetical protein Mext_3497 1 None None None 163851408 Common - iron permease FTR1 Mext_1981 49 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 163850266 Nonpathogen - hypothetical protein Mext_0833 1 None None None 163852804 Common - rare lipoprotein A Mext_3390 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 163852123 Nonpathogen - hypothetical protein Mext_2704 1 None None None 163852312 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_2894 38 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 163849684 Common - Catalase domain protein Mext_0230 99 COG0753 KatE, Catalase Inorganic ion transport and metabolism 163851620 Nonpathogen - hypothetical protein Mext_2197 1 None None None 163849741 Common - Catalase Mext_0289 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 163852306 Nonpathogen - hypothetical protein Mext_2888 4 None None None 163849698 Nonpathogen - hypothetical protein Mext_0245 11 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 163849748 Common - 3-isopropylmalate dehydratase, small subunit Mext_0296 211 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 163852119 Common - protein of unknown function DUF150 Mext_2700 171 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 163851587 Common - Ribosomal protein L25/L23 Mext_2164 215 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 163852572 Nonpathogen - hypothetical protein Mext_3156 1 None None None 163849964 Common - adenylyl cyclase class-3/4/guanylyl cyclase Mext_0521 50 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 163853634 Common - Enoyl-CoA hydratase/isomerase Mext_4237 134 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 163851071 Common - succinyl-CoA synthetase, beta subunit Mext_1644 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 163849781 Common - response regulator receiver Mext_0329 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163851965 Common - Cytochrome b/b6 domain Mext_2543 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 163851648 Common - glycosyl transferase group 1 Mext_2225 163 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163853315 Common - Patatin Mext_3916 12 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 163849898 Nonpathogen - hypothetical protein Mext_0449 1 None None None 163852722 Common - tRNA (guanine-N(7)-)-methyltransferase Mext_3307 158 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 163853078 Common - RibD domain protein Mext_3672 41 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 163851791 Common - Phosphoglycerate kinase Mext_2368 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 163850672 Common - heavy metal efflux pump, CzcA family Mext_1242 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 163851292 Common - CMP/dCMP deaminase zinc-binding Mext_1865 53 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 163853737 Common - efflux transporter, RND family, MFP subunit Mext_4340 112 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163854002 Common - AMP-dependent synthetase and ligase Mext_4606 190 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163850450 Common - hypothetical protein Mext_1017 3 COG4129 COG4129, Predicted membrane protein Function unknown 163852383 Common - purine nucleotide phosphorylase Mext_2966 134 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 163853304 Common - aminotransferase class IV Mext_3905 68 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 163851575 Common - LysR substrate-binding Mext_2152 112 COG0583 LysR, Transcriptional regulator Transcription 163854004 Nonpathogen - hypothetical protein Mext_4608 5 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 163851149 Common - LysR substrate-binding Mext_1722 191 COG0583 LysR, Transcriptional regulator Transcription 163852362 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Mext_2945 176 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 163853741 Common - ATP-binding region ATPase domain protein Mext_4344 146 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 163854269 Common - histidine kinase dimerisation/phosphoacceptor Mext_4873 123 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163850076 Common - Lytic transglycosylase catalytic Mext_0634 43 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 163850059 Nonpathogen - hypothetical protein Mext_0617 1 None None None 163849968 Nonpathogen - hypothetical protein Mext_0525 1 None None None 163852740 Common - Excinuclease ABC C subunit domain protein Mext_3325 33 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 163852907 Common - hypothetical protein Mext_3494 34 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 163851693 Common - ATP-binding region ATPase domain protein Mext_2270 211 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163851594 Common - ribosomal protein S17 Mext_2171 224 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 163849766 Common - arginine biosynthesis bifunctional protein ArgJ Mext_0314 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 163850446 Nonpathogen - hypothetical protein Mext_1013 1 None None None 163850032 Nonpathogen - hypothetical protein Mext_0590 1 None None None 163853977 Common - Respiratory-chain NADH dehydrogenase domain 51 kDa subunit Mext_4581 160 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 163853130 Common - ABC transporter related Mext_3728 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163854230 Common - HNH endonuclease Mext_4834 102 COG1403 McrA, Restriction endonuclease Defense mechanisms 163850044 Common - thiamine monophosphate synthase Mext_0602 27 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 163853946 Common - GGDEF family protein Mext_4550 28 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163851908 Common - type II secretion system protein Mext_2485 69 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 163853311 Common - membrane protein-like protein Mext_3912 33 COG4270 COG4270, Predicted membrane protein Function unknown 163854257 Common - major facilitator superfamily MFS_1 Mext_4861 83 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 163850669 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Mext_1239 43 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 163850126 Common - flagellar FlaF family protein Mext_0686 12 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 163850109 Common - chemotaxis sensory transducer Mext_0667 141 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163852359 Common - UDP-N-acetylmuramate--alanine ligase Mext_2942 210 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 163850538 Common - Ion transport 2 domain protein Mext_1106 66 None None None 163852627 Common - membrane protein AbrB duplication Mext_3212 46 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 163852264 Common - molybdenum cofactor synthesis domain protein Mext_2846 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 163852520 Common - acyltransferase 3 Mext_3104 9 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 163852669 Common - threonine synthase Mext_3254 195 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 163852133 Common - 1,4-alpha-glucan branching enzyme Mext_2714 147 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 163854109 Common - phosphate ABC transporter, periplasmic phosphate-binding protein Mext_4713 100 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 163852699 Common - peptidase U6 penicillin-insensitive murein endopeptidase Mext_3284 41 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 163853210 Common - hypothetical protein Mext_3808 23 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 163850576 Common - nitrate ABC transporter, ATPase subunits C and D Mext_1146 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163849931 Common - LysR substrate-binding Mext_0486 177 COG0583 LysR, Transcriptional regulator Transcription 163852443 Nonpathogen - hypothetical protein Mext_3026 1 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 163853602 Common - polyhydroxyalkanoate depolymerase, intracellular Mext_4205 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 163851435 Common - Hsp33 protein Mext_2009 135 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 163854104 Nonpathogen - hypothetical protein Mext_4708 1 None None None 163850527 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Mext_1095 187 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 163853162 Common - IucA/IucC family protein Mext_3760 40 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 163850462 Nonpathogen - hypothetical protein Mext_1029 1 None None None 163853610 Common - protein of unknown function DUF606 Mext_4213 60 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 163852972 Common - glycosyl transferase family 2 Mext_3564 51 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163850656 Common - exsB protein Mext_1226 163 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 163852601 Common - porin Mext_3186 14 None None None 163850684 Common - methionine aminopeptidase, type I Mext_1254 246 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 163850543 Common - Carbonate dehydratase Mext_1111 155 COG0583 LysR, Transcriptional regulator Transcription 163851658 Common - regulatory protein AsnC/Lrp family Mext_2235 152 COG1522 Lrp, Transcriptional regulators Transcription 163851605 Common - ribosomal protein L15 Mext_2182 209 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 163852017 Common - hypothetical protein Mext_2597 31 COG4307 COG4307, Uncharacterized protein conserved in bacteria Function unknown 163853861 Common - hypothetical protein Mext_4465 58 COG3825 COG3825, Uncharacterized protein conserved in bacteria Function unknown 163851458 Common - NAD-dependent epimerase/dehydratase Mext_2034 180 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163851521 Common - nitrogen regulatory protein P-II Mext_2098 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 163849922 Common - integrase family protein Mext_0473 32 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163852060 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mext_2640 181 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 163851531 Common - peptidase S24 and S26 domain protein Mext_2108 39 COG2932 COG2932, Predicted transcriptional regulator Transcription 163851144 Common - NMT1/THI5 like domain protein Mext_1717 80 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163849558 Common - alpha/beta hydrolase fold Mext_0102 114 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163852063 Common - chemotaxis sensory transducer Mext_2643 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163853456 Nonpathogen - hypothetical protein Mext_4058 3 None None None 163850540 Common - hypothetical protein Mext_1108 56 COG2323 COG2323, Predicted membrane protein Function unknown 163850686 Nonpathogen - hypothetical protein Mext_1256 3 None None None 163849596 Common - chemotaxis sensory transducer Mext_0141 136 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163853492 Common - flagellar hook capping protein Mext_4094 52 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 163852901 Common - ABC transporter related Mext_3488 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163851325 Nonpathogen - hypothetical protein Mext_1898 1 None None None 163851847 Nonpathogen - hypothetical protein Mext_2424 1 None None None 163853419 Common - Transglycosylase-associated protein Mext_4021 57 COG2261 COG2261, Predicted membrane protein Function unknown 163853480 Nonpathogen - Haem oxygenase Mext_4082 2 COG3230 HemO, Heme oxygenase Inorganic ion transport and metabolism 163850894 Common - ATP synthase F1, epsilon subunit Mext_1465 182 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 163850084 Common - flagellar motor switch protein FliM Mext_0642 101 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 163853435 Common - PAS sensor protein Mext_4037 143 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163853390 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Mext_3991 168 COG0546 Gph, Predicted phosphatases General function prediction only 163852791 Common - urea ABC transporter, ATP-binding protein UrtE Mext_3377 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 163851420 Common - PhnA protein Mext_1993 105 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 163850804 Common - hypothetical protein Mext_1375 13 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 163853515 Nonpathogen - hypothetical protein Mext_4117 1 None None None 163849646 Common - ABC transporter related Mext_0192 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 163852727 Common - aspartate carbamoyltransferase Mext_3312 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 163851735 Common - Glutathione S-transferase domain Mext_2312 94 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163853923 Nonpathogen - hypothetical protein Mext_4527 1 None None None 163850284 Common - response regulator receiver Mext_0851 98 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163854028 Nonpathogen - hypothetical protein Mext_4632 1 None None None 163852466 Nonpathogen - flagellar basal body-associated protein FliL Mext_3049 9 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 163852051 Common - TonB-dependent siderophore receptor Mext_2631 123 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 163853189 Common - ROSMUCR transcriptional regulator Mext_3787 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 163850777 Nonpathogen - hypothetical protein Mext_1348 2 None None None 163853448 Common - beta-lactamase Mext_4050 106 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 163853249 Nonpathogen - hypothetical protein Mext_3849 1 None None None 163850604 Common - O-acetylhomoserine sulfhydrylase-like protein Mext_1174 163 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 163853087 Common - conserved hypothetical proteinn Mext_3683 7 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 163851836 Common - Radical SAM domain protein Mext_2413 63 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 163850563 Common - formate/nitrite transporter Mext_1131 95 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 163851202 Common - Sulphur oxidation protein SoxZ Mext_1775 21 COG5501 COG5501, Predicted secreted protein Function unknown 163853984 Nonpathogen - hypothetical protein Mext_4588 5 None None None 163853368 Common - NUDIX hydrolase Mext_3969 91 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 163849974 Common - hypothetical protein Mext_0531 27 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 163854229 Common - MscS Mechanosensitive ion channel Mext_4833 223 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 163851559 Common - CsbD family protein Mext_2136 44 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 163852678 Common - cytochrome c oxidase, subunit II Mext_3263 144 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 163849562 Common - phospholipase D/Transphosphatidylase Mext_0106 80 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 163853406 Nonpathogen - hypothetical protein Mext_4007 1 None None None 163849982 Common - hypothetical protein Mext_0539 26 None None None 163853905 Common - efflux transporter, RND family, MFP subunit Mext_4509 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163851387 Nonpathogen - protein of unknown function DUF465 Mext_1960 2 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 163852010 Nonpathogen - conserved hypothetical proteinn Mext_2590 2 COG5403 COG5403, Uncharacterized conserved protein Function unknown 163852662 Nonpathogen - hypothetical protein Mext_3247 1 None None None 163850511 Common - NADH-quinone oxidoreductase, chain G Mext_1079 193 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 163854237 Common - tRNA(Ile)-lysidine synthetase Mext_4841 218 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 163853851 Common - amino acid permease-associated region Mext_4455 177 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 163851032 Nonpathogen - hypothetical protein Mext_1605 1 None None None 163851854 Nonpathogen - hypothetical protein Mext_2431 1 None None None 163849551 Common - cytochrome c oxidase, subunit I Mext_0095 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 163851743 Common - regulatory protein GntR HTH Mext_2320 206 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 163852868 Common - putative glucosyltransferase Mext_3454 24 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163851452 Common - glycogen/starch/alpha-glucan phosphorylase Mext_2028 144 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 163853553 Common - UDP-N-acetylglucosamine pyrophosphorylase Mext_4156 221 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 163853531 Common - polysaccharide export protein Mext_4134 61 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 163852872 Common - hopanoid biosynthesis associated RND transporter like protein HpnN Mext_3458 104 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 163850713 Common - ABC transporter related Mext_1284 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 163852095 Common - protein of unknown function DUF1611 Mext_2676 36 COG3367 COG3367, Uncharacterized conserved protein Function unknown 163854172 Common - penicillin-binding protein, 1A family Mext_4776 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 163853815 Nonpathogen - hypothetical protein Mext_4419 2 None None None 163850489 Common - xanthine dehydrogenase accessory factor Mext_1056 115 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 163852000 Common - large conductance mechanosensitive channel protein Mext_2579 135 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 163853578 Common - protein of unknown function DUF6 transmembrane Mext_4181 63 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 163849477 Common - hypothetical protein Mext_0020 12 COG4320 COG4320, Uncharacterized protein conserved in bacteria Function unknown 163849601 Nonpathogen - hypothetical protein Mext_0146 1 None None None 163849716 Common - protein of unknown function DUF1254 Mext_0264 35 COG5361 COG5361, Uncharacterized conserved protein Function unknown 163850918 Common - shikimate 5-dehydrogenase Mext_1489 222 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 163853382 Common - diguanylate cyclase Mext_3983 176 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163854177 Nonpathogen - hypothetical protein Mext_4781 1 None None None 163850150 Common - Protein involved in cellulose biosynthesis (CelD)-like protein Mext_0710 15 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 163851706 Nonpathogen - hypothetical protein Mext_2283 1 None None None 163850293 Common - short-chain dehydrogenase/reductase SDR Mext_0860 167 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163851643 Nonpathogen - hypothetical protein Mext_2220 1 None None None 163851550 Nonpathogen - hypothetical protein Mext_2127 1 None None None 163854260 Common - acetolactate synthase, large subunit, biosynthetic type Mext_4864 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 163849883 Nonpathogen - hypothetical protein Mext_0433 1 None None None 163852056 Nonpathogen - hypothetical protein Mext_2636 1 None None None 163851304 Nonpathogen - hypothetical protein Mext_1877 1 None None None 163849929 Common - hypothetical protein Mext_0484 17 COG2128 COG2128, Uncharacterized conserved protein Function unknown 163851651 Common - acyl-CoA dehydrogenase domain protein Mext_2228 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 163852172 Common - sigma-54 factor interaction domain-containing protein Mext_2753 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163851113 Common - hypothetical protein Mext_1686 3 None None None 163853799 Common - choline/carnitine/betaine transporter Mext_4403 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 163853617 Common - response regulator receiver Mext_4220 178 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163853373 Common - transcriptional regulator, fis family Mext_3974 14 None None None 163852161 Common - Tetratricopeptide TPR_2 repeat protein Mext_2742 36 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 163852455 Common - membrane bound O-acyl transferase MBOAT family protein Mext_3038 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 163851463 Nonpathogen - hypothetical protein Mext_2039 1 None None None 163850513 Common - NADH-quinone oxidoreductase, E subunit Mext_1081 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 163853292 Common - Nitrate and nitrite sensing domain protein Mext_3893 67 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163851348 Nonpathogen - hypothetical protein Mext_1921 3 None None None 163851866 Common - conserved hypothetical proteinn Mext_2443 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 163853762 Common - helix-turn-helix- domain containing protein AraC type Mext_4365 115 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 163853561 Common - Cold-shock protein DNA-binding Mext_4164 178 COG1278 CspC, Cold shock proteins Transcription 163850110 Common - PspA/IM30 family protein Mext_0668 16 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 163850232 Common - PAS sensor protein Mext_0798 132 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163850175 Common - HemY domain protein Mext_0735 28 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 163850690 Common - ABC transporter related Mext_1260 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163851956 Common - Extracellular ligand-binding receptor Mext_2534 133 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 163851773 Common - GTP-binding protein HSR1-related Mext_2350 188 COG0218 COG0218, Predicted GTPase General function prediction only 163854122 Common - major facilitator superfamily MFS_1 Mext_4726 71 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163853781 Common - hypothetical protein Mext_4384 2 None None None 163849524 Common - GTP-binding proten HflX Mext_0068 216 COG2262 HflX, GTPases General function prediction only 163850295 Common - ATPase associated with various cellular activities AAA_3 Mext_0862 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 163852944 Nonpathogen - hypothetical protein Mext_3533 2 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 163850783 Common - protein of unknown function DUF849 Mext_1354 60 COG3246 COG3246, Uncharacterized conserved protein Function unknown 163853176 Common - diguanylate cyclase Mext_3774 177 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163851932 Common - Methyltransferase type 11 Mext_2509 55 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163849466 Common - helicase, RecD/TraA family Mext_0009 159 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 163852994 Nonpathogen - hypothetical protein Mext_3588 1 None None None 163853777 Common - Hemolysin-type calcium-binding region Mext_4380 97 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 163851718 Common - hypothetical protein Mext_2295 3 None None None 163849580 Common - AMP-dependent synthetase and ligase Mext_0124 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163850176 Nonpathogen - hypothetical protein Mext_0736 2 None None None 163852007 Common - regulatory protein MarR Mext_2586 43 COG1846 MarR, Transcriptional regulators Transcription 163849756 Common - nuclease SbcCD, D subunit Mext_0304 104 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 163850937 Common - protein of unknown function UPF0118 Mext_1508 26 COG0628 PerM, Predicted permease General function prediction only 163853866 Common - phosphomethylpyrimidine kinase Mext_4470 217 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 163852883 Common - acetoacetyl-CoA reductase Mext_3470 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163853903 Common - short-chain dehydrogenase/reductase SDR Mext_4507 220 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 163852250 Common - efflux transporter, RND family, MFP subunit Mext_2832 48 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163851827 Common - tryptophan halogenase Mext_2404 17 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 163849675 Nonpathogen - hypothetical protein Mext_0221 4 None None None 163852073 Common - 6-phosphogluconate dehydrogenase NAD-binding Mext_2653 189 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 163851021 Nonpathogen - hypothetical protein Mext_1594 1 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 163851493 Nonpathogen - hypothetical protein Mext_2069 1 None None None 163851393 Common - fructose-1,6-bisphosphatase, class II Mext_1966 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 163853481 Common - hypothetical protein Mext_4083 10 None None None 163852970 Nonpathogen - hypothetical protein Mext_3562 1 None None None 163850394 Common - Alcohol dehydrogenase zinc-binding domain protein Mext_0961 169 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 163852534 Common - cyclic peptide transporter Mext_3118 248 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 163852144 Nonpathogen - hydroxyneurosporene synthase Mext_2725 14 None None None 163854053 Nonpathogen - hypothetical protein Mext_4657 1 COG4907 COG4907, Predicted membrane protein Function unknown 163849853 Common - oxygen-independent coproporphyrinogen III oxidase Mext_0403 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 163849513 Nonpathogen - hypothetical protein Mext_0057 1 None None None 163854072 Common - acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase Mext_4676 167 COG1043 LpxA, Acyl- acyl carrier protein 163850834 Common - cytochrome C biogenesis protein Mext_1405 90 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 163853321 Common - acriflavin resistance protein Mext_3922 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163852561 Nonpathogen - hypothetical protein Mext_3145 1 None None None 163851494 Common - aminotransferase class I and II Mext_2070 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 163852216 Nonpathogen - hypothetical protein Mext_2797 1 None None None 163850416 Nonpathogen - hypothetical protein Mext_0983 1 None None None 163853595 Nonpathogen - hypothetical protein Mext_4198 1 None None None 163850632 Common - TonB-dependent siderophore receptor Mext_1202 117 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 163853414 Common - ribosomal protein L7/L12 Mext_4016 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 163850916 Common - helix-turn-helix domain protein Mext_1487 33 COG2944 COG2944, Predicted transcriptional regulator Transcription 163852926 Nonpathogen - TadE family protein Mext_3513 9 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 163854187 Nonpathogen - hypothetical protein Mext_4791 2 None None None 163853029 Common - regulatory protein TetR Mext_3623 74 COG1309 AcrR, Transcriptional regulator Transcription 163851339 Nonpathogen - hypothetical protein Mext_1912 1 None None None 163853044 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Mext_3638 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 163850000 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Mext_0557 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163852259 Common - ATP-binding region ATPase domain protein Mext_2841 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163853313 Common - plasmid encoded RepA protein Mext_3914 19 None None None 163853112 Common - hypothetical protein Mext_3709 9 None None None 163851126 Common - inner-membrane translocator Mext_1699 104 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 163851239 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Mext_1812 203 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 163854248 Common - inner-membrane translocator Mext_4852 143 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 163851232 Common - transcriptional coactivator/pterin dehydratase Mext_1805 81 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 163851283 Common - exopolysaccharide biosynthesis polyprenyl glycosylphosphotransferase Mext_1856 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 163852494 Common - integrase family protein Mext_3077 94 COG0582 XerC, Integrase DNA replication, recombination, and repair 163854232 Common - porin opacity type Mext_4836 21 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 163850827 Common - helix-turn-helix domain protein Mext_1398 3 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 163849972 Nonpathogen - hypothetical protein Mext_0529 4 None None None 163851798 Common - Glutaminase Mext_2375 72 COG2066 GlsA, Glutaminase Amino acid transport and metabolism 163851051 Common - translation initiation factor IF-3 Mext_1624 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 163850349 Common - Amidase Mext_0916 217 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 163851699 Common - methyltransferase small Mext_2276 93 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 163852238 Common - nitrogen regulation protein NR(I) Mext_2820 215 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163851146 Common - binding-protein-dependent transport systems inner membrane component Mext_1719 159 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163851358 Common - Lytic transglycosylase catalytic Mext_1931 66 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 163850741 Common - hypothetical protein Mext_1312 2 COG1289 COG1289, Predicted membrane protein Function unknown 163852128 Nonpathogen - hypothetical protein Mext_2709 1 None None None 163851630 Common - DNA repair protein RadC Mext_2207 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 163853477 Common - short-chain dehydrogenase/reductase SDR Mext_4079 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163850773 Nonpathogen - hypothetical protein Mext_1344 1 None None None 163853780 Common - Peptidoglycan-binding domain 1 protein Mext_4383 12 COG3409 COG3409, Putative peptidoglycan-binding domain-containing protein Cell envelope biogenesis, outer membrane 163851675 Common - peptidase S16 lon domain protein Mext_2252 106 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 163849484 Common - hypothetical protein Mext_0028 13 None None None 163850585 Common - SSS sodium solute transporter superfamily Mext_1155 143 COG4147 DhlC, Predicted symporter General function prediction only 163851174 Common - EAL domain protein Mext_1747 162 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 163851991 Nonpathogen - hypothetical protein Mext_2569 1 None None None 163852855 Common - phytoene desaturase Mext_3441 89 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 163852637 Common - Nitrate reductase Mext_3222 187 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 163849725 Common - helicase domain protein Mext_0273 136 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 163849622 Nonpathogen - hypothetical protein Mext_0168 1 None None None 163852116 Common - translation initiation factor IF-2 Mext_2697 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 163853723 Common - Glutamine--fructose-6-phosphate transaminase (isomerizing) Mext_4326 230 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 163850004 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Mext_0561 165 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 163850484 Common - DNA repair protein RecO Mext_1051 37 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 163853774 Nonpathogen - hypothetical protein Mext_4377 1 None None None 163851274 Common - 40-residue YVTN family beta-propeller repeat protein Mext_1847 91 COG3391 COG3391, Uncharacterized conserved protein Function unknown 163854149 Common - glutamyl-tRNA synthetase Mext_4753 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 163853524 Common - Hemolysin-type calcium-binding region Mext_4127 37 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 163850995 Nonpathogen - hypothetical protein Mext_1568 4 None None None 163850117 Common - flagellin domain protein Mext_0677 118 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 163850963 Common - UV damage repair endonuclease Mext_1536 21 COG4294 Uve, UV damage repair endonuclease DNA replication, recombination, and repair 163850358 Common - regulatory protein MarR Mext_0925 83 COG1846 MarR, Transcriptional regulators Transcription 163852139 Common - Diaminopimelate epimerase Mext_2720 185 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 163850286 Common - glycine dehydrogenase Mext_0853 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 163850166 Common - Disulphide bond formation protein DsbB Mext_0726 4 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 163851189 Common - peptide methionine sulfoxide reductase Mext_1762 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 163852431 Common - Urease accessory protein UreF Mext_3014 68 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 163850082 Common - hypothetical protein Mext_0640 8 None None None 163853075 Common - Xanthine/uracil/vitamin C permease Mext_3669 138 COG2252 COG2252, Permeases General function prediction only 163851081 Common - sarcosine oxidase, beta subunit family Mext_1654 100 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 163851267 Common - putative exported protein of unknown function Mext_1840 13 None None None 163851838 Common - trigger factor Mext_2415 211 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 163851150 Common - Amidohydrolase 3 Mext_1723 72 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 163852233 Common - aldehyde oxidase and xanthine dehydrogenase molybdopterin binding Mext_2815 119 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 163852948 Nonpathogen - hypothetical protein Mext_3537 1 None None None 163852899 Common - binding-protein-dependent transport systems inner membrane component Mext_3486 162 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163849933 Nonpathogen - hypothetical protein Mext_0488 1 None None None 163852596 Common - DNA methylase N-4/N-6 domain protein Mext_3181 123 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 163849669 Common - chaperone protein HtpG Mext_0215 26 None None None 163851686 Common - Patatin Mext_2263 122 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 163849707 Common - Prophage CP4-57 regulatory Mext_0255 7 COG3311 AlpA, Predicted transcriptional regulator Transcription 163853156 Common - binding-protein-dependent transport systems inner membrane component Mext_3754 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 163853887 Common - oxidoreductase FAD/NAD(P)-binding domain protein Mext_4491 98 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 163850264 Common - glycosyl transferase family 2 Mext_0831 123 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163852269 Common - ABC transporter related Mext_2851 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 163850613 Nonpathogen - hypothetical protein Mext_1183 1 None None None 163851323 Nonpathogen - hypothetical protein Mext_1896 2 None None None 163853500 Common - secretion protein HlyD family protein Mext_4102 131 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163853663 Common - acyl-CoA dehydrogenase domain protein Mext_4266 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 163851083 Common - glutamine amidotransferase class-II Mext_1656 230 COG0067 GltB, Glutamate synthase domain 1 Amino acid transport and metabolism 163851569 Common - 4-oxalocrotonate tautomerase Mext_2146 30 None None None 163850473 Common - cobyrinic acid a,c-diamide synthase Mext_1040 136 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 163851811 Common - Methylmalonyl-CoA mutase Mext_2388 107 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 163850423 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Mext_0990 184 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 163853702 Common - DNA-3-methyladenine glycosylase I Mext_4305 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 163849803 Common - hypothetical protein Mext_0353 11 None None None 163852812 Common - Beta-N-acetylhexosaminidase Mext_3398 169 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 163851010 Common - glucose inhibited division protein A Mext_1583 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 163850597 Common - ABC transporter related Mext_1167 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163852776 Common - PAS sensor protein Mext_3362 198 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163850341 Common - protein of unknown function DUF1289 Mext_0908 33 COG3313 COG3313, Predicted Fe-S protein General function prediction only 163853687 Common - protein of unknown function DUF344 Mext_4290 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 163851022 Common - TonB-dependent siderophore receptor Mext_1595 108 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 163851800 Common - glutamine synthetase, type I Mext_2377 230 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 163851784 Common - hypothetical protein Mext_2361 24 None None None 163852348 Common - GMP synthase, large subunit Mext_2931 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 163851019 Common - Prephenate dehydrogenase Mext_1592 149 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 163852755 Common - cytochrome c, class I Mext_3340 27 COG3258 COG3258, Cytochrome c Energy production and conversion 163854098 Nonpathogen - hypothetical protein Mext_4702 1 None None None 163853065 Common - ribonuclease, Rne/Rng family Mext_3659 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 163853698 Nonpathogen - hypothetical protein Mext_4301 5 None None None 163850432 Common - Adenylosuccinate synthase Mext_0999 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 163853674 Nonpathogen - hypothetical protein Mext_4277 1 None None None 163853757 Common - regulatory protein TetR Mext_4360 107 COG1309 AcrR, Transcriptional regulator Transcription 163849875 Common - Beta-ketoacyl synthase Mext_0425 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163851971 Nonpathogen - hypothetical protein Mext_2549 5 None None None 163850753 Nonpathogen - hypothetical protein Mext_1324 1 None None None 163852613 Common - Scaffold protein Nfu/NifU Mext_3198 91 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 163854091 Common - hypothetical protein Mext_4695 25 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 163850701 Common - SMP-30/Gluconolaconase/LRE domain protein Mext_1271 71 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 163851008 Common - PAS sensor protein Mext_1581 48 None None None 163849961 Common - ABC transporter related Mext_0518 248 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 163851374 Common - Beta-ketoacyl synthase Mext_1947 218 COG3321 COG3321, Polyketide synthase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 163849525 Nonpathogen - hypothetical protein Mext_0069 1 None None None 163851901 Common - peptidase A24A prepilin type IV Mext_2478 24 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 163850552 Common - hypothetical protein Mext_1120 20 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163852274 Common - periplasmic glucan biosynthesis protein Mext_2856 54 COG2943 MdoH, Membrane glycosyltransferase Cell envelope biogenesis, outer membrane 163853589 Common - Ornithine carbamoyltransferase Mext_4192 158 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 163851073 Common - 2-oxoglutarate dehydrogenase, E1 subunit Mext_1646 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 163850165 Common - DedA family Mext_0725 47 COG1238 COG1238, Predicted membrane protein Function unknown 163854032 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Mext_4636 216 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 163849783 Common - ABC transporter related Mext_0331 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163849762 Common - protein of unknown function DUF427 Mext_0310 51 COG2343 COG2343, Uncharacterized protein conserved in bacteria Function unknown 163852211 Common - hypothetical protein Mext_2792 3 None None None 163854045 Common - Enoyl-CoA hydratase/isomerase Mext_4649 162 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 163851382 Common - Sel1 domain protein repeat-containing protein Mext_1955 91 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 163850115 Common - aspartate aminotransferase Mext_0675 55 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 163852422 Common - translation elongation factor P Mext_3005 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 163853952 Common - heat shock protein Hsp20 Mext_4556 75 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 163850247 Nonpathogen - hypothetical protein Mext_0814 1 None None None 163849830 Common - ABC transporter related Mext_0380 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 163850216 Common - 5-formyltetrahydrofolate cyclo-ligase Mext_0779 61 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 163851138 Common - peptidase S15 Mext_1711 57 COG2936 COG2936, Predicted acyl esterases General function prediction only 163853962 Common - molybdopterin-guanine dinucleotide biosynthesis protein A Mext_4566 69 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 163850521 Common - transcription elongation factor GreA Mext_1089 204 COG0782 GreA, Transcription elongation factor Transcription 163850601 Common - Alkanesulfonate monooxygenase Mext_1171 77 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 163853632 Common - regulatory protein MarR Mext_4235 26 COG1846 MarR, Transcriptional regulators Transcription 163853214 Common - protein of unknown function UPF0118 Mext_3812 118 COG0628 PerM, Predicted permease General function prediction only 163852396 Common - Auxin Efflux Carrier Mext_2979 107 COG0679 COG0679, Predicted permeases General function prediction only 163849603 Nonpathogen - hypothetical protein Mext_0148 1 None None None 163851724 Common - pyridine nucleotide-disulphide oxidoreductase dimerisation region Mext_2301 247 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 163853581 Common - hypothetical protein Mext_4184 42 COG2346 COG2346, Truncated hemoglobins General function prediction only 163851211 Common - hypothetical protein Mext_1784 32 COG3768 COG3768, Predicted membrane protein Function unknown 163852921 Common - UspA domain protein Mext_3508 46 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 163850766 Common - cytochrome c550 Mext_1337 15 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 163851440 Common - peptidase M48 Ste24p Mext_2014 58 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 163851131 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Mext_1704 144 COG0388 COG0388, Predicted amidohydrolase General function prediction only 163852132 Common - trehalose synthase Mext_2713 175 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 163851370 Common - squalene-associated FAD-dependent desaturase Mext_1943 38 COG3349 COG3349, Uncharacterized conserved protein Function unknown 163853582 Common - beta-lactamase-like protein Mext_4185 77 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 163850733 Common - UreE urease accessory domain protein Mext_1304 10 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 163851488 Nonpathogen - hypothetical protein Mext_2064 1 None None None 163851468 Common - GCN5-related N-acetyltransferase Mext_2044 30 COG3153 COG3153, Predicted acetyltransferase General function prediction only 163850812 Common - peptidase C14 caspase catalytic subunit p20 Mext_1383 30 COG4249 COG4249, Uncharacterized protein containing caspase domain General function prediction only 163852417 Common - hypothetical protein Mext_3000 17 None None None 163850259 Common - chloramphenicol acetyltransferase Mext_0826 84 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 163850464 Common - Glycerone kinase Mext_1031 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 163850230 Common - sulfatase Mext_0793 75 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 163853892 Common - twin-arginine translocation pathway signal Mext_4496 88 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163854211 Common - light-independent protochlorophyllide reductase, B subunit Mext_4815 46 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 163849743 Common - hypothetical protein Mext_0291 12 None None None 163851941 Common - efflux transporter, RND family, MFP subunit Mext_2519 159 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163852739 Nonpathogen - hypothetical protein Mext_3324 1 None None None 163850304 Nonpathogen - hypothetical protein Mext_0871 1 None None None 163853676 Common - LysR substrate-binding Mext_4279 104 COG0583 LysR, Transcriptional regulator Transcription 163850327 Common - protein of unknown function DUF330 Mext_0894 30 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 163851218 Common - hypothetical protein Mext_1791 22 COG5400 COG5400, Uncharacterized protein conserved in bacteria Function unknown 163852047 Common - protein of unknown function DUF329 Mext_2627 46 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 163853284 Common - gid protein Mext_3885 173 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 163850067 Common - flagellar L-ring protein Mext_0625 98 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 163849884 Common - hypothetical protein Mext_0434 20 None None None 163850026 Common - sulfate ABC transporter, ATPase subunit Mext_0584 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 163850132 Nonpathogen - hypothetical protein Mext_0692 2 None None None 163854218 Common - geranylgeranyl reductase Mext_4822 30 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 163851946 Common - 3-isopropylmalate dehydrogenase Mext_2524 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 163850313 Common - Integral membrane protein TerC Mext_0880 104 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 163850737 Common - urease, beta subunit Mext_1308 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 163852508 Nonpathogen - hypothetical protein Mext_3092 1 None None None 163852890 Common - DegT/DnrJ/EryC1/StrS aminotransferase Mext_3477 195 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 163852103 Common - Xylose isomerase domain protein TIM barrel Mext_2684 21 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 163850873 Nonpathogen - cobalt transporter, subunit CbtB Mext_1444 1 None None None 163851893 Nonpathogen - hypothetical protein Mext_2470 1 None None None 163852438 Common - flavin reductase domain protein FMN-binding Mext_3021 109 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 163852546 Common - alpha/beta hydrolase fold Mext_3130 177 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163853429 Common - BLUF domain protein Mext_4031 43 None None None 163850730 Common - Urease accessory protein UreD Mext_1301 69 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 163851560 Common - major facilitator superfamily MFS_1 Mext_2137 94 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 163854196 Common - Serine-type D-Ala-D-Ala carboxypeptidase Mext_4800 156 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 163850706 Common - extracellular solute-binding protein family 5 Mext_1277 191 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 163853641 Common - transferase hexapeptide repeat containing protein Mext_4244 98 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 163851582 Common - translation elongation factor G Mext_2159 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 163854081 Common - General substrate transporter Mext_4685 139 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163853461 Common - undecaprenyl diphosphate synthase Mext_4063 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 163854019 Nonpathogen - hypothetical protein Mext_4623 1 None None None 163851912 Common - CoA-binding domain protein Mext_2489 117 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 163852207 Nonpathogen - hypothetical protein Mext_2788 3 None None None 163853169 Nonpathogen - hypothetical protein Mext_3767 1 None None None 163852290 Common - conserved hypothetical protein; putative transcriptional regulatory protein Mext_2872 37 COG1510 COG1510, Predicted transcriptional regulators Transcription 163854193 Nonpathogen - hypothetical protein Mext_4797 1 None None None 163851414 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Mext_1987 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 163852514 Nonpathogen - hypothetical protein Mext_3098 3 None None None 163852711 Common - haloacid dehalogenase, type II Mext_3296 55 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 163852982 Common - pectate lyase L precursor Mext_3575 16 None None None 163853910 Common - Autoinducer-binding domain protein Mext_4514 67 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 163849951 Nonpathogen - hypothetical protein Mext_0507 10 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 163852097 Nonpathogen - Lytic transglycosylase catalytic Mext_2678 12 None None None 163850896 Common - ATP synthase F1, gamma subunit Mext_1467 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 163851045 Common - MotA/TolQ/ExbB proton channel Mext_1618 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 163851544 Common - PepSY-associated TM helix domain protein Mext_2121 31 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 163853565 Common - Acyl-CoA synthetase (AMP-forming)/AMP-acid ligase II-like protein Mext_4168 23 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163852648 Common - Class I peptide chain release factor Mext_3233 108 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 163849458 Common - chromosomal replication initiator protein DnaA Mext_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 163851353 Common - ATP-binding region ATPase domain protein Mext_1926 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163853925 Common - (2Fe-2S)-binding domain protein Mext_4529 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 163851403 Common - cytochrome bd ubiquinol oxidase subunit I Mext_1976 165 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 163852843 Common - major facilitator superfamily MFS_1 Mext_3429 189 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163853479 Common - histidine kinase dimerisation/phosphoacceptor Mext_4081 115 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 163853262 Nonpathogen - protein of unknown function DUF1328 Mext_3862 1 COG5487 COG5487, Small integral membrane protein Function unknown 163853612 Common - response regulator receiver Mext_4215 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163853729 Nonpathogen - hypothetical protein Mext_4332 1 None None None 163851314 Common - protein of unknown function DUF1452 Mext_1887 26 COG5478 COG5478, Predicted small integral membrane protein Function unknown 163850408 Nonpathogen - protein of unknown function DUF306 Meta and HslJ Mext_0975 6 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 163849861 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_0411 77 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163852473 Common - NAD(P)H dehydrogenase (quinone) Mext_3056 70 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 163853396 Common - transcription termination/antitermination factor NusG Mext_3997 215 COG0250 NusG, Transcription antiterminator Transcription 163854262 Common - acetolactate synthase, small subunit Mext_4866 188 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 163853802 Common - formate dehydrogenase, alpha subunit Mext_4406 215 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 163853819 Common - hypothetical protein Mext_4423 14 None None None 163852553 Nonpathogen - hypothetical protein Mext_3137 13 None None None 163852718 Common - peptidase M48 Ste24p Mext_3303 130 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 163852465 Common - flagellar basal body rod protein Mext_3048 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 163849779 Common - hypothetical protein Mext_0327 14 COG5482 COG5482, Uncharacterized conserved protein Function unknown 163853789 Common - RNA-binding S4 domain protein Mext_4393 105 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 163851471 Common - GCN5-related N-acetyltransferase Mext_2047 17 COG0456 RimI, Acetyltransferases General function prediction only 163852020 Common - glutathione S-transferase Mext_2600 72 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163851666 Common - single-strand binding protein Mext_2243 202 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 163853517 Common - PepSY-associated TM helix domain protein Mext_4119 39 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 163849585 Nonpathogen - hypothetical protein Mext_0130 1 None None None 163850137 Nonpathogen - hypothetical protein Mext_0697 4 None None None 163850970 Common - Electron transfer flavoprotein alpha subunit Mext_1543 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 163852659 Common - acetyl-CoA acetyltransferase Mext_3244 181 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 163853959 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Mext_4563 43 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 163849868 Common - chemotaxis protein Mext_0418 12 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163854173 Common - adenylyl cyclase class-3/4/guanylyl cyclase Mext_4777 63 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 163851245 Common - coenzyme PQQ biosynthesis protein C Mext_1818 38 COG5424 COG5424, Pyrroloquinoline quinone (Coenzyme PQQ) biosynthesis protein C Coenzyme metabolism 163853917 Common - hypothetical protein Mext_4521 11 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163853549 Nonpathogen - hypothetical protein Mext_4152 5 None None None 163851841 Common - ATP-dependent protease La Mext_2418 234 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 163853221 Common - esterase, PHB depolymerase family Mext_3819 37 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 163851367 Common - hopanoid-associated sugar epimerase Mext_1940 211 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163852285 Common - glutamate 5-kinase Mext_2867 191 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 163852703 Common - Redoxin domain protein Mext_3288 145 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 163852598 Nonpathogen - hypothetical protein Mext_3183 7 None None None 163852227 Common - hexapeptide transferase family protein Mext_2808 167 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 163851528 Common - oxidoreductase alpha (molybdopterin) subunit Mext_2105 173 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 163853187 Common - Chromosome segregation ATPase-like protein Mext_3785 141 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 163851296 Nonpathogen - hypothetical protein Mext_1869 1 None None None 163851538 Nonpathogen - hypothetical protein Mext_2115 1 None None None 163853306 Common - para-aminobenzoate synthase, subunit I Mext_3907 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 163853743 Common - regulatory protein LuxR Mext_4346 158 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163852802 Common - Cobyrinic acid ac-diamide synthase Mext_3388 103 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 163851257 Common - protein of unknown function DUF201 Mext_1830 9 COG2232 COG2232, Predicted ATP-dependent carboligase related to biotin carboxylase General function prediction only 163849502 Nonpathogen - hypothetical protein Mext_0046 6 None None None 163850368 Common - DNA-3-methyladenine glycosylase Mext_0935 83 COG2094 Mpg, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 163852650 Common - Methyltransferase type 12 Mext_3235 82 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 163849789 Common - hypothetical protein Mext_0337 28 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 163851711 Common - peptidase M23B Mext_2288 95 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 163849649 Common - hypothetical protein Mext_0195 3 None None None 163851199 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Mext_1772 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 163853105 Nonpathogen - hypothetical protein Mext_3701 1 None None None 163851016 Nonpathogen - hypothetical protein Mext_1589 1 None None None 163851573 Nonpathogen - hypothetical protein Mext_2150 8 None None None 163853495 Common - Phosphatidylethanolamine N-methyltransferase Mext_4097 132 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163853463 Common - Ankyrin Mext_4065 106 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 163854119 Common - cobyric acid synthase CobQ Mext_4723 151 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 163852801 Nonpathogen - hypothetical protein Mext_3387 1 None None None 163853121 Nonpathogen - hypothetical protein Mext_3719 1 None None None 163849817 Common - CsbD family protein Mext_0367 4 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 163849879 Nonpathogen - tetratricopeptide TPR_4 protein Mext_0429 9 None None None 163853739 Common - regulatory protein TetR Mext_4342 10 COG1309 AcrR, Transcriptional regulator Transcription 163853980 Common - hypothetical protein Mext_4584 7 None None None 163849864 Common - Formate--tetrahydrofolate ligase Mext_0414 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 163853886 Common - LysR substrate-binding Mext_4490 111 COG0583 LysR, Transcriptional regulator Transcription 163850302 Common - hypothetical protein Mext_0869 20 COG0753 KatE, Catalase Inorganic ion transport and metabolism 163852904 Common - ABC transporter related Mext_3491 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 163852570 Common - DEAD/H associated domain protein Mext_3154 156 COG1201 Lhr, Lhr-like helicases General function prediction only 163850620 Common - PAS sensor protein Mext_1190 163 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163853600 Common - short-chain dehydrogenase/reductase SDR Mext_4203 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163849962 Common - alpha/beta hydrolase fold Mext_0519 85 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163850120 Common - protein of unknown function DUF1217 Mext_0680 19 None None None 163850992 Nonpathogen - hypothetical protein Mext_1565 1 None None None 163851365 Nonpathogen - hypothetical protein Mext_1938 1 None None None 163852401 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Mext_2984 219 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 163853403 Common - glycosyl transferase family 2 Mext_4004 109 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163852445 Common - nucleotide sugar dehydrogenase Mext_3028 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 163853099 Common - conserved hypothetical cytosolic protein Mext_3695 15 None None None 163851093 Nonpathogen - hypothetical protein Mext_1666 7 COG2345 COG2345, Predicted transcriptional regulator Transcription 163849819 Common - acetylornithine deacetylase (ArgE) Mext_0369 206 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 163851661 Common - putative hydroxamate-type ferrisiderophore receptor Mext_2238 41 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 163849471 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mext_0014 234 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 163851645 Nonpathogen - hypothetical protein Mext_2222 1 None None None 163852705 Nonpathogen - hypothetical protein Mext_3290 1 None None None 163850057 Common - carbamoyl-phosphate synthase, small subunit Mext_0615 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 163851967 Common - methylthioadenosine phosphorylase Mext_2545 132 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 163853071 Common - (2Fe-2S)-binding domain protein Mext_3665 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 163852117 Common - protein of unknown function DUF448 Mext_2698 50 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 163852329 Common - GCN5-related N-acetyltransferase Mext_2912 81 COG0456 RimI, Acetyltransferases General function prediction only 163851768 Common - MOSC domain containing protein Mext_2345 44 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 163852154 Nonpathogen - antenna complex alpha/beta subunit Mext_2735 4 None None None 163853964 Common - porin Mext_4568 15 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 163852938 Nonpathogen - hypothetical protein Mext_3527 1 None None None 163851589 Common - ribosomal protein S19 Mext_2166 241 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 163853092 Common - hypothetical protein Mext_3688 31 None None None 163852785 Common - Amidase Mext_3371 216 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 163849509 Common - acetate kinase Mext_0053 162 COG0282 ackA, Acetate kinase Energy production and conversion 163849746 Common - tryptophanyl-tRNA synthetase Mext_0294 238 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163851871 Nonpathogen - hypothetical protein Mext_2448 1 COG4800 COG4800, Predicted transcriptional regulator with an HTH domain Transcription 163850452 Common - short-chain dehydrogenase/reductase SDR Mext_1019 210 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 163850674 Nonpathogen - hypothetical protein Mext_1244 1 None None None 163849546 Common - transcriptional regulator protein-like protein Mext_0090 29 COG4957 COG4957, Predicted transcriptional regulator Transcription 163852909 Common - Acyl-CoA dehydrogenase type 2 domain Mext_3496 40 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 163853721 Nonpathogen - hypothetical protein Mext_4324 1 None None None 163853363 Common - ABC transporter related Mext_3964 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 163851809 Common - Glutathione S-transferase domain Mext_2386 64 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163853009 Nonpathogen - hypothetical protein Mext_3603 1 None None None 163850334 Common - glutamate--cysteine ligase Mext_0901 53 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 163851078 Common - Sarcosine oxidase gamma subunit Mext_1651 27 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 163851261 Common - formaldehyde-activating enzyme Mext_1834 27 COG1795 COG1795, Uncharacterized conserved protein Function unknown 163853545 Common - cytochrome c class I Mext_4148 14 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 163851166 Common - Tetracycline transcriptional regulator YcdC domain protein Mext_1739 85 COG1309 AcrR, Transcriptional regulator Transcription 163850102 Common - D-3-phosphoglycerate dehydrogenase Mext_0660 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 163849463 Common - ATP-dependent DNA helicase RecQ Mext_0006 221 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 163851030 Common - conserved hypothetical protein; putative acyl-CoA N-acyltransferase related protein Mext_1603 10 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 163851861 Common - ROSMUCR transcriptional regulator Mext_2438 33 COG4957 COG4957, Predicted transcriptional regulator Transcription 163850387 Common - protein-(glutamine-N5) methyltransferase, release factor-specific Mext_0954 207 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 163849613 Common - hypothetical protein Mext_0159 3 None None None 163852967 Common - sugar transferase Mext_3559 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 163852691 Common - response regulator receiver Mext_3276 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163850206 Nonpathogen - hypothetical protein Mext_0766 1 None None None 163851998 Common - DNA gyrase, B subunit Mext_2577 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 163850201 Nonpathogen - hypothetical protein Mext_0761 1 None None None 163853494 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Mext_4096 218 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 163851927 Nonpathogen - hypothetical protein Mext_2504 1 None None None 163852218 Common - lipoic acid synthetase Mext_2799 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 163849635 Common - hypothetical protein Mext_0181 3 None None None 163849980 Common - peptidase M23B Mext_0537 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 163852446 Common - hypothetical protein Mext_3029 6 None None None 163852188 Common - cyanate lyase Mext_2769 41 COG1513 CynS, Cyanate lyase Inorganic ion transport and metabolism 163852266 Common - molybdenum cofactor synthesis domain protein Mext_2848 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 163850957 Common - CheW domain protein Mext_1530 88 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 163852934 Common - Hemolysin-type calcium-binding region Mext_3523 92 None None None 163850928 Common - HAD-superfamily hydrolase, subfamily IIA Mext_1499 65 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 163852303 Common - prolipoprotein diacylglyceryl transferase Mext_2885 192 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 163850832 Common - high-affinity nickel-transporter Mext_1403 32 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 163849573 Nonpathogen - hypothetical protein Mext_0117 2 None None None 163854200 Common - 5-aminolevulinic acid synthase Mext_4804 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 163852808 Nonpathogen - hypothetical protein Mext_3394 1 None None None 163852671 Common - Surfeit locus 1 family protein Mext_3256 62 COG3346 COG3346, Uncharacterized conserved protein Function unknown 163850988 Common - MltA domain protein Mext_1561 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 163850921 Nonpathogen - Capsular polysaccharide biosynthesis protein-like protein Mext_1492 12 COG4421 COG4421, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism 163853937 Common - Alcohol dehydrogenase zinc-binding domain protein Mext_4541 205 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 163851820 Common - secretion protein HlyD family protein Mext_2397 151 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163852585 Common - ATP-cone domain protein Mext_3169 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 163850142 Common - cytochrome d ubiquinol oxidase, subunit II Mext_0702 146 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 163851700 Common - pseudouridine synthase Mext_2277 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 163853022 Common - chemotaxis sensory transducer Mext_3616 62 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163851110 Common - LysR substrate-binding Mext_1683 186 COG0583 LysR, Transcriptional regulator Transcription 163852328 Nonpathogen - hypothetical protein Mext_2911 1 None None None 163850548 Common - NAD-dependent epimerase/dehydratase Mext_1116 18 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163852406 Common - hypothetical protein Mext_2989 16 None None None 163852957 Nonpathogen - hypothetical protein Mext_3549 1 None None None 163852356 Common - inosine-5'-monophosphate dehydrogenase Mext_2939 243 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 163850647 Common - formyl-CoA transferase Mext_1217 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 163853705 Common - exodeoxyribonuclease VII, small subunit Mext_4308 123 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 163850697 Common - septum site-determining protein MinC Mext_1267 74 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 163853241 Common - alpha/beta hydrolase fold Mext_3841 156 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163854013 Nonpathogen - hypothetical protein Mext_4617 1 None None None 163853041 Common - molybdate ABC transporter, ATPase subunit Mext_3635 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 163849841 Common - formate dehydrogenase, gamma subunit Mext_0391 68 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 163850609 Common - hypothetical protein Mext_1179 16 None None None 163852035 Common - protein of unknown function DUF224 cysteine-rich region domain protein Mext_2615 155 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 163850892 Nonpathogen - hypothetical protein Mext_1463 3 None None None 163853336 Common - alanine racemase Mext_3937 199 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 163853921 Nonpathogen - hypothetical protein Mext_4525 1 None None None 163851845 Common - hypothetical protein Mext_2422 17 None None None 163852009 Common - hypothetical protein Mext_2588 8 None None None 163852579 Common - UbiA prenyltransferase Mext_3163 34 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 163851176 Common - OmpW family protein Mext_1749 45 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 163850157 Nonpathogen - hypothetical protein Mext_0717 1 None None None 163852392 Nonpathogen - hypothetical protein Mext_2975 1 None None None 163851107 Common - LysR substrate-binding Mext_1680 157 COG0583 LysR, Transcriptional regulator Transcription 163849733 Common - ATP12 ATPase Mext_0281 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 163853173 Common - protein of unknown function DUF526 Mext_3771 32 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 163853343 Common - protein of unknown function DUF1696 Mext_3944 29 None None None 163850182 Common - helicase, RecD/TraA family Mext_0742 124 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 163851830 Common - helix-turn-helix- domain containing protein AraC type Mext_2407 38 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 163853841 Common - acetyl-CoA carboxylase, carboxyl transferase, beta subunit Mext_4445 214 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 163852716 Common - glycosyl transferase family 2 Mext_3301 119 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163850053 Common - DNA primase Mext_0611 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 163853785 Common - integrase family protein Mext_4388 72 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163853466 Common - chemotaxis sensory transducer Mext_4068 127 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163853558 Common - DEAD/DEAH box helicase domain protein Mext_4161 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 163850406 Common - cysteine synthase A Mext_0973 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 163853399 Common - cytochrome P450 Mext_4000 72 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 163851474 Common - SmpA/OmlA domain protein Mext_2050 31 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 163852999 Nonpathogen - hypothetical protein Mext_3593 1 None None None 163850650 Common - Serine-type D-Ala-D-Ala carboxypeptidase Mext_1220 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 163851095 Common - response regulator receiver Mext_1668 205 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163851940 Common - aminotransferase class I and II Mext_2517 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 163853086 Common - methyltransferase FkbM family Mext_3682 67 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 163851962 Common - formyl transferase domain protein Mext_2540 208 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 163854179 Common - chaperonin Cpn10 Mext_4783 216 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 163853380 Common - FeS assembly SUF system protein Mext_3981 141 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 163852702 Common - Na+/H+ antiporter NhaA Mext_3287 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 163851748 Common - isoleucyl-tRNA synthetase Mext_2325 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163850930 Common - AMP-dependent synthetase and ligase Mext_1501 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163852364 Common - Polypeptide-transport-associated domain protein FtsQ-type Mext_2947 48 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 163850901 Common - 5'-nucleotidase Mext_1472 138 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 163850560 Nonpathogen - hypothetical protein Mext_1128 1 None None None 163852140 Common - MiaB-like tRNA modifying enzyme Mext_2721 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 163851391 Common - Tetratricopeptide TPR_2 repeat protein Mext_1964 150 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 163849564 Common - PAS sensor protein Mext_0108 113 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163854021 Common - amino acid adenylation domain protein Mext_4625 214 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 163849515 Common - inositol monophosphatase Mext_0059 180 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 163853551 Common - beta-lactamase domain protein Mext_4154 68 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 163851856 Nonpathogen - hypothetical protein Mext_2433 1 None None None 163852332 Common - ribonuclease D Mext_2915 123 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 163851851 Common - hypothetical protein Mext_2428 2 None None None 163849727 Common - AAA ATPase central domain protein Mext_0275 208 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 163851741 Common - hypothetical protein Mext_2318 13 None None None 163853446 Common - protein of unknown function UPF0074 Mext_4048 55 COG1959 COG1959, Predicted transcriptional regulator Transcription 163852470 Common - Peroxiredoxin Mext_3053 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 163852821 Common - ABC transporter related Mext_3407 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163854250 Common - hypothetical protein Mext_4854 8 None None None 163852030 Common - FAD dependent oxidoreductase Mext_2610 93 COG0579 COG0579, Predicted dehydrogenase General function prediction only 163851756 Nonpathogen - PRC-barrel Mext_2333 3 None None None 163852798 Common - Invasion associated locus B family protein Mext_3384 12 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 163852453 Common - RNA polymerase-binding protein DksA Mext_3036 158 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 163851788 Nonpathogen - hypothetical protein Mext_2365 1 None None None 163851552 Common - cytidylate kinase Mext_2129 201 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 163851628 Nonpathogen - GCN5-related N-acetyltransferase Mext_2205 3 None None None 163852170 Common - protein of unknown function DUF882 Mext_2751 60 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 163849584 Common - hypothetical protein Mext_0129 8 None None None 163853271 Common - phosphoribosylamine--glycine ligase Mext_3871 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 163851302 Common - hypothetical protein Mext_1875 4 None None None 163850471 Common - transmembrane pair domain protein Mext_1038 41 COG4125 COG4125, Predicted membrane protein Function unknown 163851858 Nonpathogen - hypothetical protein Mext_2435 1 None None None 163854272 Common - cyclic nucleotide-binding Mext_4876 114 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163853389 Nonpathogen - hypothetical protein Mext_3990 1 None None None 163849490 Common - helix-turn-helix- domain containing protein AraC type Mext_0034 75 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 163852479 Common - diguanylate cyclase Mext_3062 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163849696 Common - Myo-inositol-1-phosphate synthase Mext_0243 56 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 163852002 Nonpathogen - protein of unknown function DUF1236 Mext_2581 5 None None None 163852066 Common - nicotinate-nucleotide pyrophosphorylase Mext_2646 205 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 163852176 Common - ABC-1 domain protein Mext_2757 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 163854222 Common - 6-phosphogluconate dehydrogenase, decarboxylating Mext_4826 185 COG1023 Gnd, Predicted 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 163849714 Common - hypothetical protein Mext_0262 16 None None None 163854182 Nonpathogen - Membrane protein involved in the export of O-antigen and teichoic acid-like protein Mext_4786 7 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 163852163 Common - pyruvate kinase Mext_2744 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 163850152 Common - Protein of unknown function DUF1810 Mext_0712 28 COG5579 COG5579, Uncharacterized conserved protein Function unknown 163850981 Nonpathogen - hypothetical protein Mext_1554 5 COG4575 ElaB, Uncharacterized conserved protein Function unknown 163853661 Common - hypothetical protein Mext_4264 9 None None None 163853288 Common - uncharacterized protein-like protein Mext_3889 8 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 163853571 Common - glycosyl transferase family 2 Mext_4174 186 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163853030 Nonpathogen - hypothetical protein Mext_3624 1 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 163853499 Common - drug resistance transporter, EmrB/QacA subfamily Mext_4101 195 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163851639 Common - Silent information regulator protein Sir2 Mext_2216 138 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 163849499 Common - helix-turn-helix- domain containing protein AraC type Mext_0043 49 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 163852177 Nonpathogen - hypothetical protein Mext_2758 1 None None None 163849799 Common - glycosyl transferase family 2 Mext_0347 131 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163853735 Common - putative transmembrane transporter protein Mext_4338 120 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 163850911 Common - NUDIX hydrolase Mext_1482 10 None None None 163853132 Common - ABC transport system substrate-binding protein Mext_3730 53 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163849939 Common - diguanylate cyclase Mext_0495 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163851733 Common - hypothetical protein Mext_2310 16 None None None 163851878 Nonpathogen - hypothetical protein Mext_2455 1 None None None 163851327 Nonpathogen - transposase Mext_1900 6 None None None 163853629 Common - Protein-L-isoaspartate(D-aspartate) O-methyltransferase Mext_4232 151 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 163852838 Common - chemotaxis sensory transducer Mext_3424 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163851695 Common - holo-acyl-carrier-protein synthase Mext_2272 157 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 163853344 Nonpathogen - hypothetical protein Mext_3945 1 None None None 163852025 Common - flagellar biosynthetic protein FliQ Mext_2605 122 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 163853004 Common - LysR substrate-binding Mext_3598 159 COG0583 LysR, Transcriptional regulator Transcription 163852729 Common - protein of unknown function DUF205 Mext_3314 166 COG0344 COG0344, Predicted membrane protein Function unknown 163852780 Common - Extracellular ligand-binding receptor Mext_3366 135 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 163853792 Common - hypothetical protein Mext_4396 14 None None None 163852697 Common - hypothetical protein Mext_3282 55 COG2862 COG2862, Predicted membrane protein Function unknown 163853298 Common - glycoside hydrolase family 25 Mext_3899 42 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 163852862 Common - hypothetical protein Mext_3448 2 COG0657 Aes, Esterase/lipase Lipid metabolism 163852566 Common - response regulator receiver Mext_3150 29 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163853622 Common - Squalene/phytoene synthase Mext_4225 34 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 163850107 Common - ABC transporter related Mext_0665 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 163849594 Nonpathogen - hypothetical protein Mext_0139 1 None None None 163852193 Common - diguanylate cyclase Mext_2774 183 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163851039 Nonpathogen - flagellar FlaF family protein Mext_1612 10 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 163852339 Nonpathogen - hypothetical protein Mext_2922 1 None None None 163850448 Common - isochorismatase hydrolase Mext_1015 29 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 163853371 Common - non-ribosomal peptide synthetase Mext_3972 222 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 163849966 Common - helix-turn-helix- domain containing protein AraC type Mext_0523 68 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 163851243 Common - hypothetical protein Mext_1816 9 None None None 163852826 Nonpathogen - hypothetical protein Mext_3412 2 None None None 163853128 Common - glutamine synthetase, type III Mext_3726 220 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 163853278 Nonpathogen - hypothetical protein Mext_3878 6 None None None 163851335 Common - regulatory protein ArsR Mext_1908 87 COG0640 ArsR, Predicted transcriptional regulators Transcription 163854259 Common - protein of unknown function UPF0061 Mext_4863 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 163853854 Common - ABC-type multidrug transport system ATPase and permease components-like protein Mext_4458 24 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 163854102 Common - hypothetical protein Mext_4706 5 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 163852625 Common - Catalase Mext_3210 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 163853804 Common - LysR substrate-binding Mext_4408 173 COG0583 LysR, Transcriptional regulator Transcription 163853164 Common - hypothetical protein Mext_3762 5 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163849924 Common - regulatory protein MerR Mext_0478 51 COG0789 SoxR, Predicted transcriptional regulators Transcription 163852135 Nonpathogen - hypothetical protein Mext_2716 1 None None None 163850578 Common - ABC transporter nitrate-binding protein Mext_1148 93 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163852526 Common - porin Mext_3110 13 None None None 163852202 Common - 7-cyano-7-deazaguanine reductase Mext_2783 133 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 163852869 Common - hopanoid biosynthesis associated radical SAM protein HpnJ Mext_3455 98 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 163850999 Common - helix-turn-helix domain protein Mext_1572 29 COG2944 COG2944, Predicted transcriptional regulator Transcription 163850236 Nonpathogen - hypothetical protein Mext_0803 1 None None None 163850566 Common - hypothetical protein Mext_1134 8 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163850688 Common - sigma-54 factor interaction domain-containing protein Mext_1258 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163849642 Common - HhH-GPD family protein Mext_0188 70 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 163853896 Common - glycoside hydrolase 15-related Mext_4500 69 COG3387 SGA1, Glucoamylase and related glycosyl hydrolases Carbohydrate transport and metabolism 163852831 Common - transglutaminase domain protein Mext_3417 81 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 163852065 Common - L-aspartate oxidase Mext_2645 225 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 163852912 Common - putative transcriptional regulatory protein, Crp/Fnr family Mext_3499 23 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163850096 Common - 16S rRNA processing protein RimM Mext_0654 144 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 163852344 Common - transport system permease protein Mext_2927 182 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 163850757 Common - Alpha/beta hydrolase fold-3 domain protein Mext_1328 115 COG0657 Aes, Esterase/lipase Lipid metabolism 163851652 Common - protein of unknown function DUF6 transmembrane Mext_2229 42 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 163849984 Nonpathogen - hypothetical protein Mext_0541 2 None None None 163851506 Common - membrane-associated zinc metalloprotease Mext_2082 210 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 163852914 Common - hypothetical protein Mext_3501 13 COG5622 COG5622, Protein required for attachment to host cells Cell motility and secretion 163851681 Common - type IV pilus assembly PilZ Mext_2258 12 None None None 163850880 Nonpathogen - hypothetical protein Mext_1451 1 None None None 163851596 Common - NUDIX hydrolase Mext_2173 27 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 163850658 Nonpathogen - glycosyl transferase family 2 Mext_1228 8 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163852614 Common - peptidase M22 glycoprotease Mext_3199 184 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 163849653 Common - glycosyl transferase group 1 Mext_0199 120 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163851053 Common - glycosyl transferase group 1 Mext_1626 121 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163853194 Nonpathogen - hypothetical protein Mext_3792 1 None None None 163849555 Common - PQQ-dependent dehydrogenase, methanol/ethanol family Mext_0099 66 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 163852846 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Mext_3432 139 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 163849793 Common - cytochrome c class I Mext_0341 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 163853259 Common - aldo/keto reductase Mext_3859 180 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 163849997 Common - aminotransferase class I and II Mext_0554 182 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 163853037 Nonpathogen - hypothetical protein Mext_3631 1 None None None 163850634 Common - hypothetical protein Mext_1204 10 None None None 163852084 Common - fumarate hydratase, class II Mext_2664 224 COG0114 FumC, Fumarase Energy production and conversion 163852764 Common - HEAT domain containing protein Mext_3349 48 COG1413 COG1413, FOG: HEAT repeat Energy production and conversion 163854159 Common - protein TolQ Mext_4763 143 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 163853205 Common - diguanylate cyclase Mext_3803 182 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 163849644 Nonpathogen - hypothetical protein Mext_0190 1 None None None 163852015 Common - Redoxin domain protein Mext_2595 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 163852950 Common - hypothetical protein Mext_3539 14 None None None 163853428 Common - exodeoxyribonuclease III Xth Mext_4030 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 163852299 Common - putative periplasmic ligand-binding sensor protein Mext_2881 18 COG3416 COG3416, Uncharacterized protein conserved in bacteria Function unknown 163852181 Common - single-stranded-DNA-specific exonuclease RecJ Mext_2762 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 163852591 Common - conserved hypothetical proteinn Mext_3176 25 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 163850006 Common - acetate kinase Mext_0563 161 COG0282 ackA, Acetate kinase Energy production and conversion 163852814 Common - twin-arginine translocation protein, TatB subunit Mext_3400 73 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 163853323 Common - agmatinase Mext_3924 144 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 163850645 Nonpathogen - hypothetical protein Mext_1215 2 None None None 163850883 Common - chemotaxis sensory transducer Mext_1454 121 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163850290 Common - 8-amino-7-oxononanoate synthase Mext_0857 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 163850279 Common - glucose-1-phosphate cytidylyltransferase Mext_0846 184 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 163853114 Common - hypothetical protein Mext_3711 4 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163852243 Common - GTP-binding proten HflX Mext_2825 221 COG2262 HflX, GTPases General function prediction only 163850703 Common - Carbohydrate-selective porin OprB Mext_1274 12 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 163851034 Common - cytochrome oxidase assembly Mext_1607 41 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 163852774 Nonpathogen - hypothetical protein Mext_3360 1 None None None 163850849 Common - hypothetical protein Mext_1420 29 COG5449 COG5449, Uncharacterized conserved protein Function unknown 163851567 Common - major facilitator superfamily MFS_1 Mext_2144 39 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163852045 Nonpathogen - hypothetical protein Mext_2625 1 None None None 163852681 Common - Glutamate synthase (ferredoxin) Mext_3266 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 163850775 Nonpathogen - hypothetical protein Mext_1346 2 None None None 163851128 Common - basic membrane lipoprotein Mext_1701 79 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 163852114 Common - tRNA pseudouridine synthase B Mext_2695 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 163851887 Common - Protein of unknown function YqcI/YcgG Mext_2464 8 COG3403 COG3403, Uncharacterized conserved protein Function unknown 163852737 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Mext_3322 163 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 163852524 Common - Polyprenyl synthetase Mext_3108 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 163853426 Common - ribosomal protein S15 Mext_4028 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 163853016 Common - Enoyl-CoA hydratase/isomerase Mext_3610 124 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 163853522 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I Mext_4125 233 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 163851796 Common - carbohydrate kinase, YjeF related protein Mext_2373 197 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 163849955 Common - NAD-dependent epimerase/dehydratase Mext_0511 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163852450 Common - type IV pilus assembly PilZ Mext_3033 11 None None None 163852229 Common - hypothetical protein Mext_2810 19 COG4551 COG4551, Predicted protein tyrosine phosphatase General function prediction only 163852568 Common - hypothetical protein Mext_3152 13 None None None 163849667 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mext_0213 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 163851447 Common - conserved hypothetical selenoprotein Mext_2021 30 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 163853171 Common - pyrroline-5-carboxylate reductase Mext_3769 209 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 163853148 Common - NADH:flavin oxidoreductase/NADH oxidase Mext_3746 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 163852231 Common - (2Fe-2S)-binding domain protein Mext_2813 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 163854129 Common - protein of unknown function DUF949 Mext_4733 53 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 163852782 Common - ABC transporter related Mext_3368 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 163850318 Nonpathogen - hypothetical protein Mext_0885 1 None None None 163850094 Common - chorismate mutase Mext_0652 69 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 163850721 Common - regulatory protein TetR Mext_1292 30 COG1309 AcrR, Transcriptional regulator Transcription 163852960 Common - regulatory protein Crp Mext_3552 52 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163850965 Common - Hypoxia induced protein conserved region Mext_1538 8 None None None 163849620 Common - hypothetical protein Mext_0166 35 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 163850002 Common - 3-oxoacyl-(acyl-carrier-protein) synthase 2 Mext_0559 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163849660 Common - metal-dependent phosphohydrolase HD sub domain Mext_0206 216 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 163850046 Nonpathogen - thiamine biosynthesis protein ThiS Mext_0604 4 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 163850324 Common - protein of unknown function DUF140 Mext_0891 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 163851632 Common - protein of unknown function DUF403 Mext_2209 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 163851272 Nonpathogen - hypothetical protein Mext_1845 9 None None None 163852635 Common - hypothetical protein Mext_3220 87 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 163852880 Nonpathogen - hypothetical protein Mext_3467 1 None None None 163849655 Nonpathogen - putative sugar transferase Mext_0201 6 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163853889 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mext_4493 191 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 163850421 Common - hypothetical protein Mext_0988 10 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 163853534 Common - response regulator receiver Mext_4137 184 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163850993 Common - Integral membrane protein TerC Mext_1566 95 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 163853063 Common - phosphate-selective porin O and P Mext_3657 23 COG3746 OprP, Phosphate-selective porin Inorganic ion transport and metabolism 163851190 Common - bacterioferritin Mext_1763 109 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 163852889 Common - NUDIX hydrolase Mext_3476 19 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 163854244 Common - porphobilinogen deaminase Mext_4848 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 163852346 Common - prevent-host-death family protein Mext_2929 9 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 163850743 Nonpathogen - hypothetical protein Mext_1314 1 None None None 163854246 Common - polysaccharide deacetylase Mext_4850 62 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 163853219 Common - hypothetical protein Mext_3817 13 COG3861 COG3861, Uncharacterized protein conserved in bacteria Function unknown 163850623 Common - hypothetical protein Mext_1193 11 None None None 163852459 Nonpathogen - hypothetical protein Mext_3042 4 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 163851005 Common - alanine racemase domain protein Mext_1578 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 163850395 Common - crossover junction endodeoxyribonuclease RuvC Mext_0962 194 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 163850791 Nonpathogen - cyd operon protein YbgT Mext_1362 1 COG4890 COG4890, Predicted outer membrane lipoprotein Function unknown 163851919 Nonpathogen - hypothetical protein Mext_2496 8 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 163850038 Common - response regulator receiver Mext_0596 171 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 163854075 Common - protein of unknown function DUF188 Mext_4679 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 163850078 Common - hypothetical protein Mext_0636 9 None None None 163851148 Common - NMT1/THI5 like domain protein Mext_1721 81 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163851216 Nonpathogen - hypothetical protein Mext_1789 1 None None None 163852122 Nonpathogen - hypothetical protein Mext_2703 1 None None None 163852248 Nonpathogen - hypothetical protein Mext_2830 5 None None None 163853158 Common - extracellular solute-binding protein family 5 Mext_3756 173 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 163850972 Nonpathogen - hypothetical protein Mext_1545 1 None None None 163853719 Nonpathogen - hypothetical protein Mext_4322 1 None None None 163851285 Common - polysaccharide export protein Mext_1858 95 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 163850262 Nonpathogen - hypothetical protein Mext_0829 2 None None None 163851802 Nonpathogen - hypothetical protein Mext_2379 1 None None None 163852657 Common - EAL domain protein Mext_3242 96 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 163853471 Nonpathogen - hypothetical protein Mext_4073 1 None None None 163850615 Common - Cold-shock protein DNA-binding Mext_1185 179 COG1278 CspC, Cold shock proteins Transcription 163849801 Common - flagellin domain protein Mext_0349 49 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 163853519 Common - TonB-dependent siderophore receptor Mext_4121 116 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 163850223 Nonpathogen - hypothetical protein Mext_0786 1 None None None 163851507 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Mext_2083 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 163849843 Nonpathogen - hypothetical protein Mext_0393 3 None None None 163851068 Common - Shikimate kinase., 3-dehydroquinate synthase Mext_1641 213 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 163851220 Common - glycosyl transferase group 1 Mext_1793 171 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163850936 Common - molybdopterin biosynthesis MoaE protein Mext_1507 133 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 163853141 Common - Sarcosine oxidase gamma subunit Mext_3739 21 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 163851899 Common - hypothetical protein Mext_2476 14 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 163851775 Common - ribonuclease P protein component Mext_2352 27 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 163851549 Common - hypothetical protein Mext_2126 17 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 163850536 Common - arsenical resistance protein ArsH Mext_1104 46 COG0431 COG0431, Predicted flavoprotein General function prediction only 163851473 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Mext_2049 44 COG0546 Gph, Predicted phosphatases General function prediction only 163850414 Common - hypothetical protein Mext_0981 10 COG3208 GrsT, Predicted thioesterase involved in non-ribosomal peptide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 163851868 Common - hypothetical protein Mext_2445 11 None None None 163854283 Common - ADP-ribosylation/Crystallin J1 Mext_4887 92 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 163853084 Common - transposase Mext_3680 44 None None None 163851380 Common - Ethanolamine ammonia-lyase Mext_1953 51 COG4302 EutC, Ethanolamine ammonia-lyase, small subunit Amino acid transport and metabolism 163850234 Common - HD-GYP domain-like protein Mext_0801 43 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 163851752 Common - peptidase M16 domain protein Mext_2329 173 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 163853829 Common - adenosylhomocysteinase Mext_4433 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 163854142 Nonpathogen - hypothetical protein Mext_4746 5 None None None 163849673 Common - hypothetical protein Mext_0219 28 COG2863 COG2863, Cytochrome c553 Energy production and conversion 163849754 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_0302 81 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163851683 Common - Rhomboid family protein Mext_2260 35 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 163850764 Common - 40-residue YVTN family beta-propeller repeat protein Mext_1335 89 COG3391 COG3391, Uncharacterized conserved protein Function unknown 163850692 Common - NMT1/THI5 like domain protein Mext_1262 113 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163852058 Common - Antibiotic biosynthesis monooxygenase Mext_2638 29 COG1359 COG1359, Uncharacterized conserved protein Function unknown 163851934 Common - hypothetical protein Mext_2511 10 None None None 163853834 Common - phospholipase D/Transphosphatidylase Mext_4438 150 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 163851500 Common - Inorganic diphosphatase Mext_2076 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 163849464 Nonpathogen - hypothetical protein Mext_0007 1 None None None 163851208 Common - hypothetical protein Mext_1781 12 None None None 163851418 Common - hypothetical protein Mext_1991 3 None None None 163850590 Nonpathogen - helix-turn-helix domain protein Mext_1160 4 COG1396 HipB, Predicted transcriptional regulators Transcription 163852099 Nonpathogen - hypothetical protein Mext_2680 2 None None None 163853760 Common - peptidase membrane zinc metallopeptidase putative Mext_4363 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 163850782 Common - Carbonate dehydratase Mext_1353 160 COG0583 LysR, Transcriptional regulator Transcription 163851346 Nonpathogen - hypothetical protein Mext_1919 1 None None None 163850660 Nonpathogen - hypothetical protein Mext_1230 1 None None None 163852992 Common - protein of unknown function DUF159 Mext_3586 49 COG2135 COG2135, Uncharacterized conserved protein Function unknown 163853779 Nonpathogen - hypothetical protein Mext_4382 1 None None None 163852292 Common - ABC transporter related Mext_2874 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 163850878 Common - fumarate hydratase, class II Mext_1449 233 COG0114 FumC, Fumarase Energy production and conversion 163852532 Common - Nrd protein Mext_3116 71 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 163849522 Nonpathogen - hypothetical protein Mext_0066 1 None None None 163851229 Common - Citrate (pro-3S)-lyase Mext_1802 115 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 163851197 Nonpathogen - hypothetical protein Mext_1770 1 None None None 163853768 Common - binding-protein-dependent transport systems inner membrane component Mext_4371 177 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163854185 Nonpathogen - hypothetical protein Mext_4789 1 None None None 163850199 Nonpathogen - hypothetical protein Mext_0759 1 None None None 163851983 Common - PAS sensor protein Mext_2561 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163849918 Nonpathogen - hypothetical protein Mext_0469 1 None None None 163850579 Common - Rubredoxin-type Fe(Cys)4 protein Mext_1149 137 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 163853593 Nonpathogen - hypothetical protein Mext_4196 1 None None None 163850086 Common - 20S proteasome A and B subunits Mext_0644 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 163853483 Common - Capsule polysaccharide export protein-like protein Mext_4085 35 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 163850498 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Mext_1065 209 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 163850903 Common - Rhodanese domain protein Mext_1474 31 COG4275 COG4275, Uncharacterized conserved protein Function unknown 163853991 Common - Alpha/beta hydrolase fold-3 domain protein Mext_4595 122 COG0657 Aes, Esterase/lipase Lipid metabolism 163851169 Common - protein of unknown function DUF989 Mext_1742 36 COG3748 COG3748, Predicted membrane protein Function unknown 163853449 Common - PAS sensor protein Mext_4051 219 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163853783 Nonpathogen - hypothetical protein Mext_4386 1 None None None 163853901 Common - PAS sensor protein Mext_4505 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163849946 Common - Phosphoglycerate mutase Mext_0502 118 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 163850779 Nonpathogen - hypothetical protein Mext_1350 1 None None None 163850584 Common - ThiJ/PfpI domain protein Mext_1154 73 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 163849901 Nonpathogen - protein of unknown function DUF1236 Mext_0452 6 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 163853178 Common - polyhydroxyalkanoate depolymerase, intracellular Mext_3776 43 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 163851906 Common - type II secretion system protein E Mext_2483 158 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 163850336 Nonpathogen - SirA family protein Mext_0903 1 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 163852432 Common - UreE urease accessory domain protein Mext_3015 49 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 163852874 Common - hypothetical protein Mext_3461 14 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 163849915 Nonpathogen - hypothetical protein Mext_0466 1 None None None 163850419 Common - hypothetical protein Mext_0986 18 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 163851993 Common - DEAD/DEAH box helicase domain protein Mext_2571 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 163851481 Nonpathogen - hypothetical protein Mext_2057 1 None None None 163851461 Common - polysaccharide biosynthesis protein CapD Mext_2037 138 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163853822 Common - Na+/solute symporter Mext_4426 98 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 163850190 Common - hypothetical protein Mext_0750 20 COG3644 COG3644, Uncharacterized protein conserved in bacteria Function unknown 163854153 Common - hypothetical protein Mext_4757 3 None None None 163853412 Common - phosphate-selective porin O and P Mext_4013 11 None None None 163853386 Nonpathogen - hypothetical protein Mext_3987 4 None None None 163852924 Nonpathogen - hypothetical protein Mext_3511 8 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 163851496 Common - chemotaxis sensory transducer Mext_2072 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163849795 Common - extracellular solute-binding protein family 5 Mext_0343 120 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 163851611 Common - ribosomal protein S14 Mext_2188 207 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 163853691 Common - hypothetical protein Mext_4294 9 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 163852748 Common - Usg family protein Mext_3333 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 163851747 Common - sodium:dicarboxylate symporter Mext_2324 162 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 163853282 Nonpathogen - putative site-specific integrase/recombinase Mext_3883 3 None None None 163851603 Common - adenylate kinase Mext_2180 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 163851891 Nonpathogen - hypothetical protein Mext_2468 1 None None None 163853655 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Mext_4258 12 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 163851157 Common - NMT1/THI5 like domain protein Mext_1730 83 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163853239 Common - protein of unknown function DUF442 Mext_3839 106 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 163853793 Common - Heme NO binding domain protein Mext_4397 11 None None None 163853776 Nonpathogen - hypothetical protein Mext_4379 2 None None None 163851428 Common - ABC transporter related Mext_2001 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 163854011 Common - NADH-ubiquinone oxidoreductase chain 4L Mext_4615 76 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 163853637 Common - RDD domain containing protein Mext_4240 14 COG1714 COG1714, Predicted membrane protein/domain Function unknown 163850163 Common - AraC-type transcriptional regulator domain protein Mext_0723 71 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 163852857 Common - tRNA/rRNA methyltransferase (SpoU) Mext_3443 36 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 163849486 Common - acyl transferase domain protein Mext_0030 109 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 163854051 Common - peptidase S10 serine carboxypeptidase Mext_4655 37 COG2939 COG2939, Carboxypeptidase C (cathepsin A) Amino acid transport and metabolism 163850028 Common - endonuclease III Mext_0586 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 163852505 Nonpathogen - hypothetical protein Mext_3089 1 None None None 163851411 Common - Histidinol dehydrogenase Mext_1984 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 163850024 Common - sulfate ABC transporter, inner membrane subunit CysT Mext_0582 236 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 163854279 Nonpathogen - DNA polymerase beta domain protein region Mext_4883 3 None None None 163852109 Common - heavy metal translocating P-type ATPase Mext_2690 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 163854083 Common - tartrate dehydrogenase Mext_4687 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 163852205 Common - pyruvate dehydrogenase (acetyl-transferring) E1 component, alpha subunit Mext_2786 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 163854270 Common - response regulator receiver Mext_4874 111 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163850311 Common - Collagen triple helix repeat Mext_0878 5 None None None 163851048 Common - protein of unknown function DUF1150 Mext_1621 14 COG5568 COG5568, Uncharacterized small protein Function unknown 163853975 Common - Ion transport 2 domain protein Mext_4579 51 None None None 163850034 Nonpathogen - hypothetical protein Mext_0592 1 None None None 163853954 Nonpathogen - Hemolysin-type calcium-binding region Mext_4558 1 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 163850178 Nonpathogen - hypothetical protein Mext_0738 1 None None None 163852463 Common - flagella basal body P-ring formation protein FlgA Mext_3046 40 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 163852090 Common - phenazine biosynthesis protein PhzF family Mext_2671 116 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 163853225 Common - protein of unknown function DUF1275 Mext_3824 10 COG3619 COG3619, Predicted membrane protein Function unknown 163854157 Common - protein TolA Mext_4761 12 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 163851978 Nonpathogen - hypothetical protein Mext_2556 13 None None None 163852969 Common - polysaccharide export protein Mext_3561 65 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 163850554 Common - K potassium transporter Mext_1122 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 163851416 Common - 5-aminolevulinic acid synthase Mext_1989 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 163850699 Common - cell division topological specificity factor MinE Mext_1269 70 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 163853567 Common - response regulator receiver Mext_4170 139 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163852558 Nonpathogen - hypothetical protein Mext_3142 1 None None None 163852548 Common - Glutathione S-transferase domain Mext_3132 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163850739 Common - TonB-dependent receptor plug Mext_1310 64 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 163850862 Common - phage portal protein, HK97 family Mext_1433 43 COG4695 COG4695, Phage-related protein Function unknown 163850871 Common - protein of unknown function DUF1636 Mext_1442 19 COG5469 COG5469, Predicted metal-binding protein Function unknown 163851316 Common - ATP-binding region ATPase domain protein Mext_1889 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163850850 Common - hypothetical protein Mext_1421 26 COG5448 COG5448, Uncharacterized conserved protein Function unknown 163854216 Common - bacteriochlorophyll/chlorophyll synthetase Mext_4820 75 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 163850491 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol synthase Mext_1058 45 COG2068 COG2068, Uncharacterized MobA-related protein General function prediction only 163852287 Common - nicotinate (nicotinamide) nucleotide adenylyltransferase Mext_2869 152 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 163853563 Nonpathogen - hypothetical protein Mext_4166 1 None None None 163850065 Common - flagellar P-ring protein Mext_0623 104 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 163850297 Nonpathogen - hypothetical protein Mext_0864 1 None None None 163850130 Common - flagellar biosynthesis protein FlhA Mext_0690 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 163853643 Common - phage SPO1 DNA polymerase-related protein Mext_4246 154 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 163854191 Nonpathogen - hypothetical protein Mext_4795 1 None None None 163853927 Nonpathogen - hypothetical protein Mext_4531 1 None None None 163851351 Common - Glutathione S-transferase domain Mext_1924 100 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163853915 Nonpathogen - hypothetical protein Mext_4519 1 None None None 163851518 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Mext_2094 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 163854058 Nonpathogen - preprotein translocase, SecG subunit Mext_4662 1 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 163853232 Common - efflux transporter, RND family, MFP subunit Mext_3832 154 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163853941 Common - Beta-ketoacyl synthase Mext_4545 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163853864 Common - hypothetical protein Mext_4468 95 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 163850374 Common - N-acetylmuramoyl-L-alanine amidase family 2 Mext_0941 104 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 163850810 Nonpathogen - hypothetical protein Mext_1381 1 None None None 163851024 Common - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase Mext_1597 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 163851786 Common - 5-formyltetrahydrofolate cyclo-ligase Mext_2363 190 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 163850221 Common - hypothetical protein Mext_0784 31 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163852086 Common - protein of unknown function DUF1052 Mext_2667 30 COG5321 COG5321, Uncharacterized protein conserved in bacteria Function unknown 163854108 Nonpathogen - hypothetical protein Mext_4712 1 None None None 163853510 Common - response regulator receiver Mext_4112 120 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163853328 Common - ubiquinone/menaquinone biosynthesis methyltransferase Mext_3929 208 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163849851 Common - ribonuclease PH Mext_0401 183 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 163850015 Nonpathogen - hypothetical protein Mext_0572 1 None None None 163853359 Common - porin Mext_3960 13 None None None 163853226 Common - GAF domain protein Mext_3825 82 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 163854047 Common - aromatic amino acid beta-eliminating lyase/threonine aldolase Mext_4651 106 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 163850325 Common - ABC transporter related Mext_0892 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 163854133 Common - RNA-binding S4 domain protein Mext_4737 241 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 163850755 Common - short-chain dehydrogenase/reductase SDR Mext_1326 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163850789 Common - cytochrome bd ubiquinol oxidase subunit I Mext_1360 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 163853058 Nonpathogen - hypothetical protein Mext_3652 1 None None None 163851115 Common - protein of unknown function DUF6 transmembrane Mext_1688 33 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 163850546 Common - Urea carboxylase Mext_1114 46 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 163850466 Common - major facilitator superfamily MFS_1 Mext_1033 101 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 163852551 Common - CMP/dCMP deaminase zinc-binding Mext_3135 206 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 163853658 Common - Cupin 2 conserved barrel domain protein Mext_4261 34 None None None 163852897 Common - Acyl-CoA dehydrogenase type 2 domain Mext_3484 22 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 163852424 Common - Cold-shock protein DNA-binding Mext_3007 154 COG1278 CspC, Cold shock proteins Transcription 163852276 Common - Cystathionine gamma-synthase Mext_2858 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 163853708 Common - hemolysin A Mext_4311 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 163853759 Common - glutamyl-tRNA(Gln) amidotransferase subunit A Mext_4362 3 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 163851813 Nonpathogen - hypothetical protein Mext_2390 2 None None None 163850430 Common - aminotransferase class IV Mext_0997 188 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 163851006 Common - leucyl-tRNA synthetase Mext_1579 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163853453 Common - excinuclease ABC, B subunit Mext_4055 226 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 163852832 Common - regulatory protein TetR Mext_3418 87 COG1309 AcrR, Transcriptional regulator Transcription 163850454 Common - ABC-1 domain protein Mext_1021 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 163852256 Common - chemotaxis sensory transducer Mext_2838 149 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163852213 Nonpathogen - hypothetical protein Mext_2794 1 None None None 163852146 Common - Polyprenyl synthetase Mext_2727 236 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 163850559 Common - metallophosphoesterase Mext_1127 92 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 163850735 Common - CrcB protein Mext_1306 126 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 163853624 Common - protein-export membrane protein SecF Mext_4227 204 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 163849768 Common - glutathione peroxidase Mext_0316 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 163851996 Common - thioesterase superfamily protein Mext_2575 139 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 163849873 Common - ferric-uptake regulator Mext_0423 25 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 163853289 Nonpathogen - hypothetical protein Mext_3890 3 COG4313 COG4313, Protein involved in meta-pathway of phenol degradation Energy production and conversion 163852394 Common - Tetratricopeptide TPR_2 repeat protein Mext_2977 76 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 163854170 Common - restriction endonuclease Mext_4774 17 COG1787 COG1787, Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes Defense mechanisms 163853584 Common - methionyl-tRNA synthetase Mext_4187 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163853986 Nonpathogen - hypothetical protein Mext_4590 1 None None None 163851372 Common - hypothetical protein Mext_1945 35 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 163850228 Common - integrase family protein Mext_0791 80 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 163852301 Common - protein of unknown function DUF152 Mext_2883 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 163854069 Common - molybdenum cofactor biosynthesis protein C Mext_4673 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 163849605 Common - hypothetical protein Mext_0151 11 None None None 163849496 Common - Phosphoketolase Mext_0040 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 163850071 Common - flagellar M-ring protein FliF Mext_0629 128 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 163852419 Common - Glutathione S-transferase domain Mext_3002 83 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163851935 Common - tyrosine recombinase XerD Mext_2512 222 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163852541 Nonpathogen - hypothetical protein Mext_3125 1 None None None 163849828 Nonpathogen - hypothetical protein Mext_0378 1 None None None 163853090 Common - transposase IS116/IS110/IS902 family protein Mext_3686 83 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 163853216 Common - Transglycosylase-associated protein Mext_3814 5 COG2261 COG2261, Predicted membrane protein Function unknown 163851663 Common - pantoate--beta-alanine ligase Mext_2240 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 163853097 Common - glucose-1-phosphate thymidylyltransferase Mext_3693 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 163851825 Common - Methyltransferase type 12 Mext_2402 31 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163850249 Common - capsule polysaccharide export protein-like protein Mext_0816 37 COG3524 KpsE, Capsule polysaccharide export protein Cell envelope biogenesis, outer membrane 163851726 Nonpathogen - hypothetical protein Mext_2303 4 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 163850800 Nonpathogen - hypothetical protein Mext_1371 1 None None None 163851466 Common - Homospermidine synthase Mext_2042 26 COG5310 COG5310, Homospermidine synthase Secondary metabolites biosynthesis, transport, and catabolism 163853299 Common - protein of unknown function DUF1130 Mext_3900 21 COG5483 COG5483, Uncharacterized conserved protein Function unknown 163849836 Nonpathogen - hypothetical protein Mext_0386 10 None None None 163850836 Common - CcmE/CycJ protein Mext_1407 94 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 163852646 Common - heat shock protein DnaJ domain protein Mext_3231 56 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 163850637 Common - formyl-CoA transferase Mext_1207 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 163850160 Common - regulatory protein ArsR Mext_0720 97 COG0640 ArsR, Predicted transcriptional regulators Transcription 163850882 Common - alpha/beta hydrolase fold Mext_1453 130 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163850198 Common - luciferase family protein Mext_0758 24 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 163850556 Common - short-chain dehydrogenase/reductase SDR Mext_1124 14 COG0623 FabI, Enoyl- acyl-carrier-protein 163850307 Common - ribonuclease BN Mext_0874 94 COG1295 Rbn, Predicted membrane protein Function unknown 163852987 Common - domain of unknown function DUF1738 Mext_3581 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 163854101 Nonpathogen - hypothetical protein Mext_4705 2 None None None 163853261 Common - RNA-binding S4 domain protein Mext_3861 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 163850169 Common - protein of unknown function DUF55 Mext_0729 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 163850332 Common - protein of unknown function DUF558 Mext_0899 160 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 163850040 Common - phosphoribosylformylglycinamidine synthase, purS Mext_0598 112 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 163850280 Common - CDP-glucose 4,6-dehydratase Mext_0847 131 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163851117 Common - autotransporter-associated beta strand repeat protein Mext_1690 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 163850036 Common - polyhydroxyalkanoate depolymerase, intracellular Mext_0594 44 COG4553 DepA, Poly-beta-hydroxyalkanoate depolymerase Lipid metabolism 163851004 Common - hypothetical protein Mext_1577 41 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 163854162 Nonpathogen - hypothetical protein Mext_4766 1 COG3652 COG3652, Predicted outer membrane protein Function unknown 163851133 Common - ABC transporter related Mext_1706 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 163850023 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Mext_0581 93 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 163851329 Nonpathogen - hypothetical protein Mext_1902 4 None None None 163852984 Common - regulatory protein LuxR Mext_3578 81 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163851729 Common - Uracil-DNA glycosylase superfamily Mext_2306 153 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 163851625 Nonpathogen - hypothetical protein Mext_2202 1 None None None 163850309 Common - AMP-dependent synthetase and ligase Mext_0876 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163849827 Common - alpha/beta hydrolase fold Mext_0377 161 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163851312 Common - conserved hypothetical membrane spanning protein Mext_1885 4 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 163850526 Common - 3-dehydroquinate dehydratase, type II Mext_1094 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 163852836 Common - beta-lactamase Mext_3422 149 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 163852735 Nonpathogen - hypothetical protein Mext_3320 1 None None None 163850583 Common - ThiJ/PfpI domain protein Mext_1153 113 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 163851963 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Mext_2541 209 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 163851896 Common - GTP-binding protein YchF Mext_2473 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 163852925 Common - TadE family protein Mext_3512 6 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 163850010 Common - Phosphoketolase Mext_0567 65 COG3957 COG3957, Phosphoketolase Carbohydrate transport and metabolism 163853999 Common - protein of unknown function DUF861 cupin_3 Mext_4603 22 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 163850442 Common - major facilitator superfamily MFS_1 Mext_1009 40 None None None 163852550 Common - ETC complex I subunit conserved region Mext_3134 36 None None None 163850242 Common - chemotaxis sensory transducer Mext_0809 131 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163851376 Common - glycosyl transferase family 2 Mext_1949 162 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163851356 Common - thioesterase superfamily protein Mext_1929 100 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 163852544 Common - short-chain dehydrogenase/reductase SDR Mext_3128 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163853587 Common - DNA-directed DNA polymerase Mext_4190 199 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 163852426 Common - von Willebrand factor type A Mext_3009 61 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 163854048 Common - hypothetical protein Mext_4652 30 COG3652 COG3652, Predicted outer membrane protein Function unknown 163850794 Common - response regulator receiver Mext_1365 98 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163851904 Common - pilus (Caulobacter type) biogenesis lipoprotein CpaD Mext_2481 13 COG5461 COG5461, Type IV pili component Cell motility and secretion 163850069 Common - flagellar biosynthetic protein FliP Mext_0627 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 163853656 Common - PAS sensor protein Mext_4259 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163853542 Common - hypothetical protein Mext_4145 11 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 163852616 Common - phospholipid/glycerol acyltransferase Mext_3201 97 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 163850954 Common - inositol monophosphatase Mext_1527 162 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 163851140 Common - AMP-dependent synthetase and ligase Mext_1713 217 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163853711 Common - hypothetical protein Mext_4314 4 None None None 163852577 Common - transcription antitermination factor NusB Mext_3161 161 COG0781 NusB, Transcription termination factor Transcription 163853988 Common - short-chain dehydrogenase/reductase SDR Mext_4592 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 163853484 Nonpathogen - hypothetical protein Mext_4086 1 None None None 163851381 Common - dihydroxy-acid dehydratase Mext_1954 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 163853056 Common - permease YjgP/YjgQ family protein Mext_3650 128 COG0795 COG0795, Predicted permeases General function prediction only 163852203 Common - Phosphopyruvate hydratase Mext_2784 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 163853253 Nonpathogen - hypothetical protein Mext_3853 1 None None None 163853631 Common - seryl-tRNA synthetase Mext_4234 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 163850159 Common - fatty acid desaturase Mext_0719 38 COG1398 OLE1, Fatty-acid desaturase Lipid metabolism 163849607 Nonpathogen - hypothetical protein Mext_0153 1 None None None 163850238 Nonpathogen - hypothetical protein Mext_0805 4 None None None 163849807 Nonpathogen - hypothetical protein Mext_0357 1 None None None 163854085 Common - aldo/keto reductase Mext_4689 196 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 163853332 Common - Colicin V production protein Mext_3933 17 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 163849890 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_0440 130 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 163853489 Common - flagellar motor switch protein FliG Mext_4091 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 163849704 Common - NAD-dependent epimerase/dehydratase Mext_0251 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163849687 Common - K+-transporting ATPase, B subunit Mext_0234 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 163850807 Common - protein of unknown function DUF461 Mext_1378 64 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 163849877 Common - flagellar biosynthetic protein FliP Mext_0427 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 163850940 Common - ATPase associated with various cellular activities AAA_5 Mext_1512 35 COG0714 COG0714, MoxR-like ATPases General function prediction only 163852864 Nonpathogen - hypothetical protein Mext_3450 1 None None None 163853393 Common - lipolytic protein G-D-S-L family Mext_3994 104 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 163852557 Common - isocitrate dehydrogenase, NADP-dependent Mext_3141 60 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 163853222 Common - Choloylglycine hydrolase Mext_3821 52 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 163849774 Common - UvrD/REP helicase Mext_0322 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 163854137 Common - ABC transporter related Mext_4741 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 163853351 Common - hypothetical protein Mext_3952 16 None None None 163851670 Common - hypothetical protein Mext_2247 24 COG3698 COG3698, Predicted periplasmic protein Function unknown 163850079 Common - flagellar biosynthetic protein FlhB Mext_0637 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 163850747 Nonpathogen - hypothetical protein Mext_1318 4 None None None 163854034 Common - UDP-N-acetylmuramyl-tripeptide synthetase Mext_4638 213 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 163851025 Common - Patatin Mext_1598 83 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 163853913 Common - hypothetical protein Mext_4517 13 None None None 163850133 Common - hypothetical protein Mext_0693 11 COG3951 COG3951, Rod binding protein Cell envelope biogenesis, outer membrane / Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 163853096 Common - dTDP-4-dehydrorhamnose reductase Mext_3692 164 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 163850854 Common - phage major tail protein, TP901-1 family Mext_1425 18 COG5437 COG5437, Predicted secreted protein Function unknown 163853230 Common - Chloride channel core Mext_3829 148 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 163853653 Common - GCN5-related N-acetyltransferase Mext_4256 100 COG0456 RimI, Acetyltransferases General function prediction only 163853364 Common - protein of unknown function DUF606 Mext_3965 16 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 163850062 Common - flagellar hook-basal body complex protein FliE Mext_0620 24 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 163850867 Common - precorrin-3B synthase Mext_1438 29 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 163854066 Common - glutamine amidotransferase of anthranilate synthase Mext_4670 239 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 163852342 Nonpathogen - hypothetical protein Mext_2925 3 None None None 163853287 Common - RNA polymerase sigma factor, sigma-70 family Mext_3888 105 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 163852225 Common - short-chain dehydrogenase/reductase SDR Mext_2806 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163850224 Nonpathogen - hypothetical protein Mext_0787 1 None None None 163851013 Common - parB-like partition protein Mext_1586 184 COG1475 Spo0J, Predicted transcriptional regulators Transcription 163851163 Common - Endoribonuclease L-PSP Mext_1736 176 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 163851438 Common - Nucleoside-diphosphate kinase Mext_2012 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 163852674 Common - cytochrome c oxidase assembly protein CtaG/Cox11 Mext_3259 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 163853869 Nonpathogen - hypothetical protein Mext_4473 1 None None None 163853894 Common - ANTAR domain protein Mext_4498 99 COG3707 AmiR, Response regulator with putative antiterminator output domain Signal transduction mechanisms 163851677 Common - import inner membrane translocase subunit Tim44 Mext_2254 21 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 163850218 Nonpathogen - hypothetical protein Mext_0781 1 None None None 163853236 Common - regulatory protein ArsR Mext_3836 166 COG0640 ArsR, Predicted transcriptional regulators Transcription 163851702 Common - Sel1 domain protein repeat-containing protein Mext_2279 117 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 163852461 Nonpathogen - hypothetical protein Mext_3044 1 None None None 163853620 Common - L-lactate transport Mext_4223 102 COG1620 LldP, L-lactate permease Energy production and conversion 163854274 Common - PAS fold-3 domain protein Mext_4878 6 None None None 163853266 Common - arsenical-resistance protein Mext_3866 128 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 163850530 Common - regulatory protein TetR Mext_1098 51 COG1309 AcrR, Transcriptional regulator Transcription 163850899 Common - Ferrochelatase Mext_1470 161 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 163854224 Nonpathogen - hypothetical protein Mext_4828 1 None None None 163853786 Nonpathogen - hypothetical protein Mext_4390 1 COG3918 COG3918, Predicted membrane protein Function unknown 163850869 Common - hypothetical protein Mext_1440 11 None None None 163851234 Common - binding-protein-dependent transport systems inner membrane component Mext_1807 177 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163849880 Nonpathogen - hypothetical protein Mext_0430 1 None None None 163850211 Common - response regulator receiver Mext_0773 30 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163850720 Common - molybdopterin dehydrogenase FAD-binding Mext_1291 99 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 163852714 Nonpathogen - hypothetical protein Mext_3299 5 None None None 163854056 Common - protein of unknown function DUF350 Mext_4660 16 COG3766 COG3766, Predicted membrane protein Function unknown 163852504 Common - V-type H(+)-translocating pyrophosphatase Mext_3088 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 163852246 Nonpathogen - hypothetical protein Mext_2828 1 None None None 163853185 Common - integrase family protein Mext_3783 126 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 163850213 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_0775 59 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 163849581 Common - porin Mext_0125 14 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 163852511 Common - regulatory protein LuxR Mext_3095 8 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 163854215 Common - transcriptional regulator PpsR Mext_4819 15 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163849753 Common - peptidase S9 prolyl oligopeptidase active site domain protein Mext_0301 123 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 163852288 Common - iojap-like protein Mext_2870 199 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 163852501 Common - alpha/beta hydrolase fold Mext_3084 99 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163850323 Nonpathogen - major facilitator superfamily MFS_1 Mext_0890 2 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163851207 Nonpathogen - hypothetical protein Mext_1780 1 None None None 163850817 Common - TRAP dicarboxylate transporter, DctM subunit Mext_1388 123 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 163850947 Common - orotidine 5'-phosphate decarboxylase Mext_1520 169 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 163853973 Common - hypothetical protein Mext_4577 14 None None None 163850019 Common - cyclic nucleotide-binding Mext_0576 19 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163853083 Common - transposase Mext_3679 25 None None None 163852881 Common - polyhydroxyalkanoate synthesis repressor PhaR Mext_3468 65 COG5394 COG5394, Uncharacterized protein conserved in bacteria Function unknown 163854190 Common - methylmalonyl-CoA mutase, large subunit Mext_4794 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 163850181 Common - chaperonin GroEL Mext_0741 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 163851608 Common - ribosomal protein L18 Mext_2185 214 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 163853273 Common - exodeoxyribonuclease VII, large subunit Mext_3873 199 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 163853296 Common - PAS sensor protein Mext_3897 149 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163851988 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Mext_2566 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 163851124 Common - amidohydrolase Mext_1697 167 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 163849633 Common - integration host factor, beta subunit Mext_0179 204 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 163850179 Nonpathogen - hypothetical protein Mext_0739 1 None None None 163853770 Common - hypothetical protein Mext_4373 2 COG3793 TerB, Tellurite resistance protein Inorganic ion transport and metabolism 163852975 Common - CapK related-protein Mext_3567 91 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 163850417 Common - beta-lactamase-like protein Mext_0984 14 COG1592 COG1592, Rubrerythrin Energy production and conversion 163852979 Common - polysaccharide biosynthesis protein Mext_3571 11 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 163852048 Common - maf protein Mext_2628 173 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 163850412 Common - Inositol phosphatase/fructose-16-bisphosphatase Mext_0979 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 163853011 Nonpathogen - outer membrane lipoprotein omp19 Mext_3605 2 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 163851498 Common - translation elongation factor Ts Mext_2074 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 163853706 Common - deoxyxylulose-5-phosphate synthase Mext_4309 208 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 163852997 Nonpathogen - hypothetical protein Mext_3591 1 None None None 163853423 Common - Glutathione S-transferase domain Mext_4025 84 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163851269 Common - dihydropteroate synthase DHPS Mext_1842 31 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 163853443 Common - glutamate--cysteine ligase GCS2 Mext_4045 67 COG2170 COG2170, Uncharacterized conserved protein Function unknown 163854128 Nonpathogen - hypothetical protein Mext_4732 4 None None None 163851776 Common - ribosomal protein L34 Mext_2353 189 None None None 163851599 Common - DNA-directed RNA polymerase, alpha subunit Mext_2176 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 163849958 Common - cytochrome c biogenesis protein transmembrane region Mext_0515 59 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 163852990 Nonpathogen - hypothetical protein Mext_3584 1 None None None 163853831 Common - nitroreductase Mext_4435 34 COG0778 NfnB, Nitroreductase Energy production and conversion 163849461 Common - PilT protein domain protein Mext_0004 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 163851026 Common - Methyltransferase type 11 Mext_1599 74 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163852529 Nonpathogen - hypothetical protein Mext_3113 1 None None None 163852632 Common - glutamate racemase Mext_3217 184 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 163850478 Common - Fe2+/Zn2+ uptake regulation protein-like protein Mext_1045 89 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 163852666 Common - oxidoreductase domain protein Mext_3251 172 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 163851467 Nonpathogen - hypothetical protein Mext_2043 1 None None None 163853767 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Mext_4370 38 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163853992 Common - hypothetical protein Mext_4596 18 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 163850425 Common - GCN5-related N-acetyltransferase Mext_0992 116 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 163851433 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Mext_2006 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 163852877 Common - Cof-like hydrolase Mext_3464 101 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 163851513 Common - LysR substrate-binding Mext_2089 170 COG0583 LysR, Transcriptional regulator Transcription 163850098 Common - Methyltransferase type 11 Mext_0656 93 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163851264 Nonpathogen - hypothetical protein Mext_1837 1 None None None 163850636 Common - PAS sensor protein Mext_1206 119 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 163853358 Common - hypothetical protein Mext_3959 16 None None None 163852688 Common - UDP-glucose 4-epimerase Mext_3273 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 163850973 Common - NAD(P)H quinone oxidoreductase, PIG3 family Mext_1546 199 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 163852078 Common - HflK protein Mext_2658 164 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 163853521 Common - hypothetical protein Mext_4124 62 None None None 163850694 Common - hypothetical protein Mext_1264 38 COG4325 COG4325, Predicted membrane protein Function unknown 163854206 Nonpathogen - photosynthetic reaction center H subunit Mext_4810 9 None None None 163853900 Nonpathogen - hypothetical protein Mext_4504 1 None None None 163851362 Common - ABC transporter related Mext_1935 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 163853839 Common - porin Mext_4443 9 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 163850326 Common - Mammalian cell entry related domain protein Mext_0893 82 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 163852941 Common - transposase IS3/IS911 family protein Mext_3530 59 None None None 163850997 Common - Acid phosphatase Mext_1570 31 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 163851939 Common - hypothetical protein Mext_2516 35 None None None 163849866 Common - EAL domain protein Mext_0416 61 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 163852413 Common - Carbamoyl-phosphate synthase L chain ATP-binding Mext_2996 238 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 163851566 Nonpathogen - hypothetical protein Mext_2143 1 None None None 163850595 Common - hypothetical protein Mext_1165 8 None None None 163852852 Common - ABC-2 type transporter Mext_3438 15 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 163851669 Nonpathogen - hypothetical protein Mext_2246 1 COG4371 COG4371, Predicted membrane protein Function unknown 163849680 Common - hypothetical protein Mext_0226 16 None None None 163849771 Common - delta-1-pyrroline-5-carboxylate dehydrogenase Mext_0319 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 163851787 Common - protein of unknown function DUF710 Mext_2364 35 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 163853598 Common - regulatory protein GntR HTH Mext_4201 137 COG1802 GntR, Transcriptional regulators Transcription 163852894 Nonpathogen - hypothetical protein Mext_3481 1 None None None 163853666 Common - bifunctional deaminase-reductase domain protein Mext_4269 38 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 163852589 Common - H+transporting two-sector ATPase C subunit Mext_3174 30 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 163852434 Common - protein of unknown function DUF1003 Mext_3017 46 COG4420 COG4420, Predicted membrane protein Function unknown 163852253 Common - CheW domain protein Mext_2835 23 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 163852449 Common - threonine dehydratase, biosynthetic Mext_3032 213 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 163853644 Common - Electron-transferring-flavoprotein dehydrogenase Mext_4247 109 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 163850495 Nonpathogen - hypothetical protein Mext_1062 2 None None None 163849672 Common - hypothetical protein Mext_0218 21 None None None 163851225 Common - Formiminotransferase-cyclodeaminase Mext_1798 38 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 163851504 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase Mext_2080 196 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 163852531 Nonpathogen - hypothetical protein Mext_3115 1 None None None 163849945 Common - Methyltransferase type 12 Mext_0501 89 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 163852037 Common - protein of unknown function DUF162 Mext_2617 18 COG1556 COG1556, Uncharacterized conserved protein Function unknown 163852564 Common - hypothetical protein Mext_3148 54 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 163850594 Common - Cellulose synthase (UDP-forming) Mext_1164 91 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163849528 Nonpathogen - hypothetical protein Mext_0072 3 None None None 163850100 Common - tRNA (guanine-N1)-methyltransferase Mext_0658 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 163850170 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Mext_0730 210 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 163852071 Common - hypothetical protein Mext_2651 2 None None None 163852849 Nonpathogen - phospholipid/glycerol acyltransferase Mext_3435 10 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 163852302 Common - protein of unknown function DUF185 Mext_2884 85 COG1565 COG1565, Uncharacterized conserved protein Function unknown 163850390 Common - phosphoenolpyruvate-protein phosphotransferase Mext_0957 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 163850346 Common - (2Fe-2S)-binding domain protein Mext_0913 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 163853485 Common - hypothetical protein Mext_4087 10 None None None 163850990 Common - transcription termination factor Rho Mext_1563 204 COG1158 Rho, Transcription termination factor Transcription 163849517 Common - alpha/beta hydrolase fold Mext_0061 138 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163853417 Common - extracellular solute-binding protein family 1 Mext_4019 130 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 163852147 Common - O-methyltransferase family 2 Mext_2728 15 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 163849758 Common - major facilitator superfamily MFS_1 Mext_0306 160 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 163850420 Common - polysaccharide biosynthesis protein Mext_0987 16 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 163850715 Common - inner-membrane translocator Mext_1286 160 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 163852810 Common - arginyl-tRNA synthetase Mext_3396 245 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163853504 Nonpathogen - hypothetical protein Mext_4106 1 None None None 163851319 Common - Cold-shock protein DNA-binding Mext_1892 179 COG1278 CspC, Cold shock proteins Transcription 163851047 Common - heat shock protein Hsp20 Mext_1620 66 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 163851193 Common - acyltransferase 3 Mext_1766 36 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 163850054 Common - Gluconolactonase Mext_0612 74 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 163852783 Common - ABC transporter related Mext_3369 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 163854076 Common - citrate synthase I Mext_4680 194 COG0372 GltA, Citrate synthase Energy production and conversion 163851545 Common - TonB-dependent siderophore receptor Mext_2122 110 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 163853717 Common - histidine triad (HIT) protein Mext_4320 235 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 163851171 Common - urate catabolism protein Mext_1744 67 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 163850112 Common - TonB-dependent siderophore receptor Mext_0672 121 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 163851476 Common - hypothetical protein Mext_2052 30 None None None 163851634 Nonpathogen - hypothetical protein Mext_2211 3 None None None 163853877 Common - low molecular weight phosphotyrosine protein phosphatase Mext_4481 119 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 163851215 Nonpathogen - hypothetical protein Mext_1788 1 None None None 163851885 Common - hypothetical protein Mext_2462 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 163851085 Common - ferredoxin-dependent glutamate synthase Mext_1658 205 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 163853082 Common - integrase, catalytic region Mext_3676 9 None None None 163852316 Common - regulatory protein MarR Mext_2899 139 COG1846 MarR, Transcriptional regulators Transcription 163854059 Nonpathogen - hypothetical protein Mext_4663 1 None None None 163852758 Common - xanthine permease Mext_3343 127 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 163851482 Nonpathogen - hypothetical protein Mext_2058 2 None None None 163854095 Nonpathogen - hypothetical protein Mext_4699 1 None None None 163850968 Common - ATP--cobalamin adenosyltransferase Mext_1541 128 COG2096 COG2096, Uncharacterized conserved protein Function unknown 163853410 Common - diguanylate cyclase Mext_4011 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163853930 Nonpathogen - hypothetical protein Mext_4534 1 None None None 163849870 Common - riboflavin biosynthesis protein RibF Mext_0420 210 COG0196 RibF, FAD synthase Coenzyme metabolism 163850148 Common - AMP nucleosidase Mext_0708 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 163852101 Common - oxidoreductase domain protein Mext_2682 153 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 163850838 Common - ATP-binding region ATPase domain protein Mext_1409 192 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163852043 Common - Aldose 1-epimerase Mext_2623 44 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 163852366 Common - cell division protein FtsZ Mext_2949 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 163853152 Common - Choline/ethanolamine kinase Mext_3750 16 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 163850255 Common - flagellar export protein FliJ Mext_0822 16 None None None 163850072 Common - hypothetical protein Mext_0630 7 None None None 163851076 Common - PAS sensor protein Mext_1649 189 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163852437 Common - Urease accessory protein UreD Mext_3020 74 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 163851289 Common - hypothetical protein Mext_1862 3 None None None 163850275 Nonpathogen - hypothetical protein Mext_0842 2 None None None 163853174 Common - response regulator receiver Mext_3772 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163852237 Common - PAS sensor protein Mext_2819 219 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 163851491 Common - Polyphosphate kinase Mext_2067 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 163851913 Common - thioesterase superfamily protein Mext_2490 33 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 163849744 Common - short-chain dehydrogenase/reductase SDR Mext_0292 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163850770 Nonpathogen - hypothetical protein Mext_1341 1 None None None 163850119 Nonpathogen - hypothetical protein Mext_0679 4 None None None 163853134 Common - binding-protein-dependent transport systems inner membrane component Mext_3732 183 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 163854197 Common - ATP-dependent Clp protease adaptor protein ClpS Mext_4801 118 COG2127 COG2127, Uncharacterized conserved protein Function unknown 163850315 Common - intracellular protease, PfpI family Mext_0882 176 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 163851758 Common - protein of unknown function DUF1275 Mext_2335 21 COG3619 COG3619, Predicted membrane protein Function unknown 163850121 Common - flagellar basal body rod protein Mext_0681 114 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 163852111 Common - amidohydrolase Mext_2692 165 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 163852041 Common - conserved hypothetical proteinn Mext_2621 5 COG5586 COG5586, Uncharacterized conserved protein Function unknown 163852271 Nonpathogen - hypothetical protein Mext_2853 1 None None None 163851320 Common - Cold-shock protein DNA-binding Mext_1893 178 COG1278 CspC, Cold shock proteins Transcription 163849625 Common - dienelactone hydrolase Mext_0171 36 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 163851918 Nonpathogen - CsbD family protein Mext_2495 2 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 163850339 Common - hypothetical protein Mext_0906 2 None None None 163850962 Common - urea amidolyase related protein Mext_1535 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 163849510 Nonpathogen - hypothetical protein Mext_0054 7 None None None 163850377 Common - UreE urease accessory domain protein Mext_0944 13 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 163851287 Common - hypothetical protein Mext_1860 143 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 163852379 Common - phospholipid N-methyltransferase Mext_2962 39 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 163853027 Common - regulatory protein LysR Mext_3621 84 COG0583 LysR, Transcriptional regulator Transcription 163852536 Nonpathogen - hypothetical protein Mext_3120 1 None None None 163850049 Common - hypothetical protein Mext_0607 7 None None None 163849970 Common - protein of unknown function DUF323 Mext_0527 104 COG1262 COG1262, Uncharacterized conserved protein Function unknown 163852215 Common - L-sorbosone dehydrogenase Mext_2796 66 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 163853166 Common - hypothetical protein Mext_3764 22 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 163852409 Nonpathogen - hypothetical protein Mext_2992 1 None None None 163853145 Common - electron transfer flavoprotein beta-subunit Mext_3743 5 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 163850351 Common - hypothetical protein Mext_0918 9 None None None 163853316 Common - HpcH/HpaI aldolase Mext_3917 110 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 163853401 Common - ferredoxin protein Mext_4002 6 COG1141 Fer, Ferredoxin Energy production and conversion 163854286 Common - ribosomal protein S20 Mext_4890 154 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 163851252 Common - formylmethanofuran--tetrahydromethanopterin N-formyltransferase Mext_1825 24 COG2037 Ftr, Formylmethanofuran:tetrahydromethanopterin formyltransferase Energy production and conversion 163850689 Common - ATP-binding region ATPase domain protein Mext_1259 217 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163851655 Common - sulfate adenylyltransferase, large subunit Mext_2232 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 163850031 Common - glycosyl transferase family 2 Mext_0589 73 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163852751 Common - Acyl-CoA dehydrogenase type 2 domain Mext_3336 38 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 163853753 Nonpathogen - hypothetical protein Mext_4356 1 None None None 163854024 Common - aldo/keto reductase Mext_4628 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 163849694 Common - Methyltransferase type 11 Mext_0241 102 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 163850017 Common - Kelch repeat-containing protein Mext_0574 36 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 163852032 Common - heme exporter protein CcmC Mext_2612 123 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 163851690 Common - protein of unknown function DUF37 Mext_2267 173 COG0759 COG0759, Uncharacterized conserved protein Function unknown 163853607 Common - surface presentation of antigens (SPOA) protein Mext_4210 94 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 163851615 Nonpathogen - hypothetical protein Mext_2192 1 None None None 163852779 Common - LysR substrate-binding Mext_3365 189 COG0583 LysR, Transcriptional regulator Transcription 163853127 Common - protein of unknown function DUF861 cupin_3 Mext_3725 36 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 163850561 Common - protein of unknown function DUF892 Mext_1129 21 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 163851641 Common - glycosyl transferase family 2 Mext_2218 74 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163850299 Common - von Willebrand factor type A Mext_0866 12 COG4867 COG4867, Uncharacterized protein with a von Willebrand factor type A (vWA) domain General function prediction only 163854265 Common - glutamine amidotransferase class-II Mext_4869 48 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 163853880 Nonpathogen - hypothetical protein Mext_4484 1 None None None 163851662 Common - TonB-dependent receptor plug Mext_2239 115 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 163849925 Common - TM2 domain containing protein? Mext_0479 13 None None None 163852908 Common - ABC transporter related Mext_3495 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 163850050 Common - helix-turn-helix- domain containing protein AraC type Mext_0608 42 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 163851343 Common - major facilitator superfamily MFS_1 Mext_1916 34 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163852905 Common - inner-membrane translocator Mext_3492 136 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 163852817 Common - major facilitator superfamily MFS_1 Mext_3403 140 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163853257 Common - hypothetical protein Mext_3857 18 COG3202 COG3202, ATP/ADP translocase Energy production and conversion 163851754 Common - oxidoreductase FAD/NAD(P)-binding domain protein Mext_2331 111 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 163852087 Common - periplasmic binding protein Mext_2668 91 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 163852385 Common - hypothetical protein Mext_2968 23 COG3908 COG3908, Uncharacterized protein conserved in bacteria Function unknown 163851450 Common - cyclic nucleotide-binding Mext_2024 73 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163853415 Common - DNA-directed RNA polymerase, beta subunit Mext_4017 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 163854160 Common - chemotaxis sensory transducer Mext_4764 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163850056 Common - GatB/YqeY Mext_0614 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 163852732 Nonpathogen - hypothetical protein Mext_3317 1 None None None 163850696 Common - chemotaxis sensory transducer Mext_1266 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163851035 Common - Hly-III family protein Mext_1608 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 163852391 Common - Cold-shock protein DNA-binding Mext_2974 173 COG1278 CspC, Cold shock proteins Transcription 163854252 Nonpathogen - hypothetical protein Mext_4856 1 None None None 163850680 Common - acyltransferase 3 Mext_1250 19 COG4763 COG4763, Predicted membrane protein Function unknown 163853106 Nonpathogen - hypothetical protein Mext_3702 2 None None None 163852848 Common - glycosyl transferase family 2 Mext_3434 68 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163851879 Nonpathogen - hypothetical protein Mext_2456 1 None None None 163854151 Nonpathogen - protein of unknown function DUF1656 Mext_4755 1 None None None 163850987 Common - import inner membrane translocase subunit Tim44 Mext_1560 48 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 163849728 Common - Carboxypeptidase Taq Mext_0276 82 COG2317 COG2317, Zn-dependent carboxypeptidase Amino acid transport and metabolism 163852619 Common - RNA modification enzyme, MiaB family Mext_3204 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 163851590 Common - ribosomal protein L22 Mext_2167 203 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 163853378 Common - FeS assembly protein SufD Mext_3979 170 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 163853795 Common - Glucokinase Mext_4399 90 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 163852028 Common - putative flagellar basal-body rod protein Mext_2608 34 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 163849494 Common - Kojibiose phosphorylase Mext_0038 51 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 163849529 Common - cyclic nucleotide-binding Mext_0073 100 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163849553 Common - cytochrome c class I Mext_0097 31 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 163851864 Common - hypothetical protein Mext_2441 7 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 163852318 Common - beta-lactamase domain protein Mext_2901 168 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 163852457 Nonpathogen - hypothetical protein Mext_3040 7 None None None 163853274 Common - hypothetical protein Mext_3874 24 None None None 163853978 Common - formate dehydrogenase, alpha subunit Mext_4582 215 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 163850009 Common - ABC-2 type transporter Mext_0566 109 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 163850572 Common - efflux transporter, RND family, MFP subunit Mext_1140 146 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163850467 Common - precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit Mext_1034 91 COG2241 CobL, Precorrin-6B methylase 1 Coenzyme metabolism 163851949 Common - thiamine pyrophosphate protein TPP binding domain protein Mext_2527 218 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 163853879 Common - hypothetical protein Mext_4483 2 None None None 163849639 Common - Pirin domain protein Mext_0185 139 COG1741 COG1741, Pirin-related protein General function prediction only 163850905 Nonpathogen - hypothetical protein Mext_1476 1 None None None 163851308 Common - PAS sensor protein Mext_1881 164 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163851975 Common - phosphoribosyl-ATP diphosphatase Mext_2553 148 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 163853377 Common - FeS assembly ATPase SufC Mext_3978 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 163850277 Common - regulatory protein MarR Mext_0844 40 COG1846 MarR, Transcriptional regulators Transcription 163851056 Common - phenylalanyl-tRNA synthetase, alpha subunit Mext_1629 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 163850616 Nonpathogen - conserved hypothetical protein; putative signal peptide Mext_1186 2 None None None 163853384 Nonpathogen - hypothetical protein Mext_3985 1 None None None 163852080 Common - Thymidylate synthase Mext_2660 143 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 163849999 Common - malonyl CoA-acyl carrier protein transacylase Mext_0556 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 163850476 Common - major facilitator superfamily MFS_1 Mext_1043 75 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163850533 Common - NADH:ubiquinone oxidoreductase 17.2 kD subunit Mext_1101 38 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 163849797 Common - GCN5-related N-acetyltransferase Mext_0345 93 COG3153 COG3153, Predicted acetyltransferase General function prediction only 163852053 Nonpathogen - hypothetical protein Mext_2633 1 None None None 163851564 Nonpathogen - hypothetical protein Mext_2141 1 None None None 163851738 Nonpathogen - hypothetical protein Mext_2315 1 None None None 163852694 Common - protein of unknown function DUF1178 Mext_3279 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 163852374 Common - PspA/IM30 family protein Mext_2957 7 COG1842 PspA, Phage shock protein A (IM30), suppresses sigma54-dependent transcription Transcription / Signal transduction mechanisms 163852142 Common - signal recognition particle-docking protein FtsY Mext_2723 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 163852609 Common - orotate phosphoribosyltransferase Mext_3194 101 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 163851833 Nonpathogen - hypothetical protein Mext_2410 1 None None None 163853020 Common - protein of unknown function DUF892 Mext_3614 37 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 163850840 Common - response regulator receiver Mext_1411 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163850890 Common - protein of unknown function DUF1285 Mext_1461 43 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 163850700 Common - cytochrome P450 Mext_1270 70 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 163851556 Common - Creatininase Mext_2133 86 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 163851613 Common - ribosomal protein L24 Mext_2190 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 163851789 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Mext_2366 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 163851709 Common - protein of unknown function DUF610 YibQ Mext_2286 57 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 163850292 Nonpathogen - hypothetical protein Mext_0859 1 None None None 163853983 Nonpathogen - hypothetical protein Mext_4587 1 None None None 163849565 Common - response regulator receiver Mext_0109 30 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 163853843 Common - NUDIX hydrolase Mext_4447 107 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 163852003 Common - aminotransferase class I and II Mext_2582 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 163853847 Nonpathogen - hypothetical protein Mext_4451 1 None None None 163853465 Common - alpha/beta hydrolase fold Mext_4067 124 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 163852498 Common - CHAD domain containing protein Mext_3081 94 COG3025 COG3025, Uncharacterized conserved protein Function unknown 163852173 Common - oligoendopeptidase, pepF/M3 family Mext_2754 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 163852664 Nonpathogen - hypothetical protein Mext_3249 5 None None None 163853325 Nonpathogen - hypothetical protein Mext_3926 5 None None None 163851098 Common - Histidine kinase Mext_1671 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163850980 Nonpathogen - hypothetical protein Mext_1553 1 None None None 163852076 Common - protease Do Mext_2656 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 163851542 Common - putative CobW family cobalimin synthesis protein Mext_2119 64 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 163849988 Common - glucose-6-phosphate 1-dehydrogenase Mext_0545 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 163852701 Nonpathogen - hypothetical protein Mext_3286 3 None None None 163851535 Common - Shikimate kinase Mext_2112 192 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 163849545 Common - transcriptional regulator protein-like protein Mext_0089 14 COG4957 COG4957, Predicted transcriptional regulator Transcription 163852679 Common - formate dehydrogenase family accessory protein FdhD Mext_3264 135 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 163850493 Common - formyl transferase domain protein Mext_1060 133 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 163849651 Nonpathogen - hypothetical protein Mext_0197 3 None None None 163853433 Common - NAD+ synthetase Mext_4035 187 COG0171 NadE, NAD synthase Coenzyme metabolism 163851361 Common - phosphopentomutase Mext_1934 70 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 163850128 Common - flagellar hook capping protein Mext_0688 100 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 163852723 Common - DNA topoisomerase I Mext_3308 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 163852108 Common - Histidine kinase Mext_2689 221 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 163851112 Nonpathogen - Cupin 2 conserved barrel domain protein Mext_1685 5 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 163854111 Common - phosphate ABC transporter, inner membrane subunit PstA Mext_4715 226 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 163853806 Common - GTP-binding protein Obg/CgtA Mext_4410 249 COG0536 Obg, Predicted GTPase General function prediction only 163849612 Nonpathogen - hypothetical protein Mext_0158 1 None None None 163853198 Nonpathogen - hypothetical protein Mext_3796 1 None None None 163850089 Common - hypothetical protein Mext_0647 96 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 163853191 Common - hypothetical protein Mext_3789 2 None None None 163849940 Nonpathogen - hypothetical protein Mext_0496 1 None None None 163850397 Common - Holliday junction DNA helicase RuvA Mext_0964 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 163850389 Common - hypothetical protein Mext_0956 7 COG5504 COG5504, Predicted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 163850516 Common - NADH-quinone oxidoreductase, B subunit Mext_1084 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 163851155 Common - aldehyde oxidase and xanthine dehydrogenase molybdopterin binding Mext_1728 122 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 163852014 Common - homoserine kinase Mext_2594 63 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 163853136 Common - putative signal peptide Mext_3734 15 None None None 163852447 Nonpathogen - hypothetical protein Mext_3030 1 None None None 163853532 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Mext_4135 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 163850625 Common - Urease accessory protein UreF Mext_1195 24 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 163851745 Nonpathogen - hypothetical protein Mext_2322 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 163854060 Common - hypothetical protein Mext_4664 4 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 163852336 Common - 3-oxoacid CoA-transferase, A subunit Mext_2919 99 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 163853033 Common - beta-Ig-H3/fasciclin Mext_3627 69 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 163853649 Common - cystathionine beta-lyase Mext_4252 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 163851557 Common - diguanylate cyclase Mext_2134 183 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 163854155 Common - Glutathione S-transferase domain Mext_4759 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163852958 Nonpathogen - hypothetical protein Mext_3550 1 None None None 163852592 Common - DsbA oxidoreductase Mext_3177 86 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 163853301 Nonpathogen - hypothetical protein Mext_3902 1 None None None 163851679 Common - transglutaminase family protein cysteine peptidase BTLCP Mext_2256 15 COG3672 COG3672, Predicted periplasmic protein Function unknown 163850487 Common - Extracellular ligand-binding receptor Mext_1054 136 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 163850456 Common - peptidase M23B Mext_1023 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 163851333 Nonpathogen - hypothetical protein Mext_1906 1 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 163851970 Common - Imidazoleglycerol-phosphate dehydratase Mext_2548 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 163852480 Common - diguanylate cyclase Mext_3063 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163850745 Common - alpha/beta hydrolase fold Mext_1316 150 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163851108 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_1681 43 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 163851636 Nonpathogen - hypothetical protein Mext_2213 1 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 163853713 Common - protein of unknown function DUF482 Mext_4316 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 163849572 Common - Cupin 2 conserved barrel domain protein Mext_0116 10 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 163853147 Common - protein of unknown function DUF224 cysteine-rich region domain protein Mext_3745 85 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 163853345 Nonpathogen - hypothetical protein Mext_3946 1 None None None 163850507 Common - NADH-ubiquinone oxidoreductase chain 4L Mext_1075 133 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 163852223 Common - hypothetical protein Mext_2804 3 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163850439 Common - GTPase EngC Mext_1006 163 COG1162 COG1162, Predicted GTPases General function prediction only 163851297 Nonpathogen - hypothetical protein Mext_1870 1 None None None 163851547 Common - oxidoreductase molybdopterin binding Mext_2124 82 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 163853784 Nonpathogen - hypothetical protein Mext_4387 1 None None None 163854203 Nonpathogen - hypothetical protein Mext_4807 7 None None None 163849480 Common - malonate decarboxylase, alpha subunit Mext_0024 27 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 163850509 Common - NADH-quinone oxidoreductase, chain I Mext_1077 194 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 163849736 Common - regulatory protein TetR Mext_0284 24 COG1309 AcrR, Transcriptional regulator Transcription 163851200 Common - Thioredoxin domain Mext_1773 87 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 163849739 Common - hypothetical protein Mext_0287 11 None None None 163851397 Nonpathogen - hypothetical protein Mext_1970 1 None None None 163851981 Nonpathogen - hypothetical protein Mext_2559 1 None None None 163852599 Nonpathogen - hypothetical protein Mext_3184 1 None None None 163850809 Common - electron transport protein SCO1/SenC Mext_1380 104 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 163853460 Common - hypothetical protein Mext_4062 25 COG1846 MarR, Transcriptional regulators Transcription 163853002 Common - iron dependent repressor Mext_3596 95 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 163853842 Common - tryptophan synthase, alpha subunit Mext_4446 216 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 163853939 Common - SH3 type 3 domain protein Mext_4543 2 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 163852489 Nonpathogen - conserved hypothetical protein; putative exported protein Mext_3072 1 None None None 163853140 Common - sarcosine oxidase, alpha subunit family Mext_3738 180 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 163852989 Nonpathogen - hypothetical protein Mext_3583 1 None None None 163853183 Common - MaoC domain protein dehydratase Mext_3781 59 COG2030 MaoC, Acyl dehydratase Lipid metabolism 163853125 Common - hypothetical protein Mext_3723 57 COG3665 COG3665, Uncharacterized conserved protein Function unknown 163854144 Common - hypothetical protein Mext_4748 9 None None None 163853528 Common - NAD-dependent epimerase/dehydratase Mext_4131 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163853944 Common - phosphopantetheine-binding Mext_4548 37 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163849913 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_0464 6 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 163850203 Nonpathogen - hypothetical protein Mext_0763 1 None None None 163849531 Common - hypothetical protein Mext_0075 34 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163849721 Common - Sel1 domain protein repeat-containing protein Mext_0269 26 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 163853497 Common - ATP-binding region ATPase domain protein Mext_4099 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163850912 Common - esterase, PHB depolymerase family Mext_1483 33 COG3509 LpqC, Poly(3-hydroxybutyrate) depolymerase Secondary metabolites biosynthesis, transport, and catabolism 163851767 Common - MOSC domain containing protein Mext_2344 39 COG3217 COG3217, Uncharacterized Fe-S protein General function prediction only 163852357 Common - cell cycle protein Mext_2940 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 163849544 Nonpathogen - hypothetical protein Mext_0088 1 None None None 163849892 Common - transposase IS3/IS911 family protein Mext_0442 59 None None None 163850885 Common - hypothetical protein Mext_1456 34 COG5426 COG5426, Uncharacterized membrane protein Function unknown 163853007 Common - succinate dehydrogenase, hydrophobic membrane anchor protein Mext_3601 35 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 163851682 Common - protein of unknown function DUF1457 Mext_2259 14 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 163853242 Common - periplasmic binding protein Mext_3842 44 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 163852644 Common - cobalt chelatase, pCobT subunit Mext_3229 42 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 163851511 Common - HPP family protein? Mext_2087 87 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 163852185 Common - protein of unknown function DUF490 Mext_2766 106 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 163854006 Common - Radical SAM domain protein Mext_4610 73 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 163850403 Nonpathogen - hypothetical protein Mext_0970 1 None None None 163851209 Common - PAS sensor protein Mext_1782 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163853726 Common - Asparaginase Mext_4329 137 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 163850652 Nonpathogen - hypothetical protein Mext_1222 1 None None None 163851862 Nonpathogen - hypothetical protein Mext_2439 1 None None None 163852708 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Mext_3293 132 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 163851256 Common - Methylene-tetrahydromethanopterin dehydrogenase Mext_1829 8 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 163850676 Common - hypothetical protein Mext_1246 63 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 163850986 Common - protein-export protein SecB Mext_1559 109 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 163850643 Common - CBS domain containing protein Mext_1213 20 COG0517 COG0517, FOG: CBS domain General function prediction only 163851436 Common - Carbohydrate-selective porin OprB Mext_2010 24 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 163851584 Common - ribosomal protein S10 Mext_2161 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 163851872 Common - hypothetical protein Mext_2449 14 None None None 163852656 Common - 3-hydroxyacyl-CoA dehydrogenase NAD-binding Mext_3241 170 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 163851236 Common - PQQ-dependent dehydrogenase, methanol/ethanol family Mext_1809 58 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 163853540 Common - von Willebrand factor type A Mext_4143 9 None None None 163853400 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mext_4001 189 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 163853909 Common - autoinducer synthesis protein Mext_4513 14 COG3916 LasI, N-acyl-L-homoserine lactone synthetase Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 163853731 Common - cytochrome o ubiquinol oxidase subunit IV Mext_4334 60 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 163853920 Common - Pyrrolo-quinoline quinone Mext_4524 68 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 163849470 Common - glutaredoxin-like protein Mext_0013 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 163851601 Common - ribosomal protein S11 Mext_2178 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 163853473 Common - acetylornithine and succinylornithine aminotransferase Mext_4075 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 163851270 Common - aspartate/glutamate/uridylate kinase Mext_1843 13 COG2054 COG2054, Uncharacterized archaeal kinase related to aspartokinases, uridylate kinases General function prediction only 163851730 Common - Alcohol dehydrogenase GroES domain protein Mext_2307 205 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 163852321 Nonpathogen - hypothetical protein Mext_2904 3 None None None 163852151 Common - chlorophyllide reductase subunit Z Mext_2732 32 COG2710 NifD, Nitrogenase molybdenum-iron protein, alpha and beta chains Energy production and conversion 163850875 Common - regulatory protein MarR Mext_1446 13 COG1846 MarR, Transcriptional regulators Transcription 163851646 Nonpathogen - phasin Mext_2223 8 COG5490 COG5490, Uncharacterized conserved protein Function unknown 163851178 Nonpathogen - hypothetical protein Mext_1751 1 None None None 163851961 Common - short-chain dehydrogenase/reductase SDR Mext_2539 182 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 163853048 Common - alpha/beta hydrolase fold Mext_3642 133 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163850977 Common - Alpha,alpha-trehalose-phosphate synthase (UDP-forming) Mext_1550 97 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 163849952 Nonpathogen - glycosyl transferase group 1 Mext_0508 11 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163849833 Nonpathogen - hypothetical protein Mext_0383 8 None None None 163850824 Common - alpha-2-macroglobulin domain protein Mext_1395 81 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 163853572 Common - lipid A biosynthesis domain protein Mext_4175 24 COG3952 COG3952, Predicted membrane protein Function unknown 163853159 Common - TonB-dependent siderophore receptor Mext_3757 85 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 163853650 Common - helix-turn-helix- domain containing protein AraC type Mext_4253 53 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 163853318 Common - diguanylate cyclase Mext_3919 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 163852951 Common - HNH endonuclease Mext_3540 4 None None None 163849816 Common - CsbD family protein Mext_0366 34 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 163854145 Common - OmpA/MotB domain protein Mext_4749 51 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 163849786 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Mext_0334 82 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163849591 Common - diguanylate cyclase Mext_0136 196 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163850926 Common - ATP phosphoribosyltransferase Mext_1497 203 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 163849977 Nonpathogen - hypothetical protein Mext_0534 4 None None None 163853967 Common - hypothetical protein Mext_4571 10 None None None 163852403 Common - fatty acid desaturase Mext_2986 34 COG3239 DesA, Fatty acid desaturase Lipid metabolism 163851354 Nonpathogen - hypothetical protein Mext_1927 1 None None None 163851921 Common - protein of unknown function DUF1239 Mext_2498 19 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 163851195 Common - Radical SAM domain protein Mext_1768 106 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 163853339 Common - hypothetical protein Mext_3940 10 None None None 163851181 Common - gamma-glutamyltransferase Mext_1754 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 163852254 Common - Protein-glutamate O-methyltransferase Mext_2836 150 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 163853745 Nonpathogen - hypothetical protein Mext_4348 2 None None None 163850665 Common - PTS system fructose subfamily IIA component Mext_1235 100 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 163851672 Common - Glutathione S-transferase domain Mext_2249 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163853684 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_4287 121 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 163849965 Nonpathogen - hypothetical protein Mext_0522 1 None None None 163851795 Common - amino acid permease-associated region Mext_2372 93 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 163850581 Common - OsmC family protein Mext_1151 35 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 163850956 Common - ATP-binding region ATPase domain protein Mext_1529 184 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 163851014 Common - DNA polymerase III, delta subunit Mext_1587 48 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 163852261 Common - metallothionein family 14 Mext_2843 6 None None None 163850382 Common - BLUF domain protein Mext_0949 18 None None None 163851404 Common - regulatory protein LuxR Mext_1977 115 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163854165 Common - Peptidoglycan-binding domain 1 protein Mext_4769 77 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 163853330 Common - short-chain dehydrogenase/reductase SDR Mext_3931 222 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163851424 Nonpathogen - hypothetical protein Mext_1997 1 None None None 163852468 Nonpathogen - hypothetical protein Mext_3051 4 None None None 163854130 Common - ribosomal protein L19 Mext_4734 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 163850815 Common - TRAP dicarboxylate transporter- DctP subunit Mext_1386 93 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 163851742 Nonpathogen - hypothetical protein Mext_2319 1 None None None 163851399 Common - hypothetical protein Mext_1972 28 COG3897 COG3897, Predicted methyltransferase General function prediction only 163853228 Common - protease Do Mext_3827 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 163853956 Common - protein of unknown function UPF0118 Mext_4560 148 COG0628 PerM, Predicted permease General function prediction only 163852415 Common - acylphosphatase Mext_2998 117 COG1254 AcyP, Acylphosphatases Energy production and conversion 163854054 Common - glutathionylspermidine synthase Mext_4658 52 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 163849790 Common - protein of unknown function DUF497 Mext_0338 2 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 163854036 Common - putative exported protein of unknown function Mext_4640 18 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 163852428 Common - phytoene desaturase Mext_3011 93 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 163849943 Common - hypothetical protein Mext_0499 13 None None None 163854038 Common - DNA ligase, NAD-dependent Mext_4642 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 163849519 Nonpathogen - hypothetical protein Mext_0063 4 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 163852977 Common - glycosyl transferase group 1 Mext_3569 52 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163853357 Common - fumarate lyase Mext_3958 232 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 163852251 Nonpathogen - conserved hypothetical protein; putative esterase/lipase/thioesterase domains Mext_2833 2 None None None 163853646 Common - RarD protein, DMT superfamily transporter Mext_4249 90 COG2962 RarD, Predicted permeases General function prediction only 163854131 Nonpathogen - DNA polymerase, beta domain protein region Mext_4735 2 None None None 163851705 Common - K potassium transporter Mext_2282 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 163852476 Common - sodium:dicarboxylate symporter Mext_3059 163 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 163851943 Common - acriflavin resistance protein Mext_2521 179 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163851526 Common - PAS sensor protein Mext_2103 107 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163854176 Nonpathogen - hypothetical protein Mext_4780 3 None None None 163851322 Common - response regulator receiver Mext_1895 42 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163852168 Common - protein of unknown function DUF1244 Mext_2749 38 COG3492 COG3492, Uncharacterized protein conserved in bacteria Function unknown 163854063 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Mext_4667 136 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 163849845 Common - regulatory protein TetR Mext_0395 90 COG1309 AcrR, Transcriptional regulator Transcription 163850469 Common - diguanylate cyclase Mext_1036 174 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 163852295 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Mext_2877 197 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 163850852 Nonpathogen - hypothetical protein Mext_1423 4 None None None 163852555 Common - PAS sensor protein Mext_3139 218 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163850435 Common - diguanylate cyclase Mext_1002 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163851470 Common - periplasmic glucan biosynthesis protein MdoG Mext_2046 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 163850060 Common - flagellar basal body rod protein Mext_0618 31 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 163853673 Common - major facilitator superfamily MFS_1 Mext_4276 135 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163852575 Common - short-chain dehydrogenase/reductase SDR Mext_3159 207 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 163849831 Common - 4Fe-4S ferredoxin iron-sulfur binding domain protein Mext_0381 50 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 163849689 Common - Osmosensitive K channel His kinase sensor Mext_0236 221 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 163853089 Common - hypothetical protein Mext_3685 11 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 163853670 Common - binding-protein-dependent transport systems inner membrane component Mext_4273 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 163853918 Common - hypothetical protein Mext_4522 16 None None None 163853859 Common - ROSMUCR transcriptional regulator Mext_4463 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 163853911 Nonpathogen - hypothetical protein Mext_4515 2 None None None 163851479 Common - histone family protein DNA-binding protein Mext_2055 194 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 163852439 Nonpathogen - hypothetical protein Mext_3022 1 None None None 163851571 Nonpathogen - hypothetical protein Mext_2148 1 None None None 163850361 Common - penicillin-binding protein, 1A family Mext_0928 204 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 163853312 Common - MazG family protein Mext_3913 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 163854213 Nonpathogen - 2-vinyl bacteriochlorophyllide hydratase Mext_4817 14 None None None 163853234 Common - cytochrome bd ubiquinol oxidase subunit I Mext_3834 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 163854267 Common - hypothetical protein Mext_4871 10 None None None 163850226 Common - cyclic nucleotide-binding Mext_0789 28 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163853506 Common - KaiB domain protein Mext_4108 24 None None None 163851011 Common - methyltransferase GidB Mext_1584 154 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 163853788 Common - translation elongation factor Tu Mext_4392 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 163849776 Common - MIP family channel protein Mext_0324 128 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 163853043 Common - hypothetical protein Mext_3637 4 None None None 163854195 Common - heat shock protein DnaJ domain protein Mext_4799 25 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 163851242 Common - hypothetical protein Mext_1815 14 None None None 163853293 Common - efflux transporter, RND family, MFP subunit Mext_3894 148 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163850520 Common - carbamoyl-phosphate synthase, large subunit Mext_1088 233 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 163851444 Common - protein of unknown function DUF477 Mext_2018 7 COG3762 COG3762, Predicted membrane protein Function unknown 163854064 Common - anthranilate synthase component I Mext_4668 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 163849475 Common - ATP-binding region ATPase domain protein Mext_0018 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163854226 Common - MotA/TolQ/ExbB proton channel Mext_4830 82 COG1291 MotA, Flagellar motor component Cell motility and secretion 163852273 Common - periplasmic glucan biosynthesis protein MdoG Mext_2855 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 163850021 Nonpathogen - hypothetical protein Mext_0578 1 None None None 163850749 Common - hypothetical protein Mext_1320 61 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 163852515 Common - glycyl-tRNA synthetase, alpha subunit Mext_3099 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 163849908 Common - response regulator receiver Mext_0459 185 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 163850353 Common - protein of unknown function DUF519 Mext_0920 84 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 163853430 Common - diguanylate cyclase Mext_4032 177 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163852092 Nonpathogen - hypothetical protein Mext_2673 1 None None None 163854016 Common - NAD-dependent epimerase/dehydratase Mext_4620 219 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163850768 Common - PQQ-dependent dehydrogenase, methanol/ethanol family Mext_1339 75 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 163853246 Common - hypothetical protein Mext_3846 47 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 163850889 Common - thioesterase superfamily protein Mext_1460 26 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 163853437 Common - hypothetical protein Mext_4039 23 None None None 163853867 Common - Thiamine-phosphate diphosphorylase Mext_4471 200 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 163850215 Common - cytochrome P450 Mext_0777 86 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 163853285 Common - Hemolysin-type calcium-binding region Mext_3886 23 None None None 163851173 Common - protein of unknown function DUF808 Mext_1746 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 163850731 Common - urease accessory protein UreG Mext_1302 130 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 163853094 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Mext_3690 167 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 163853773 Common - short-chain dehydrogenase/reductase SDR Mext_4376 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 163851135 Common - basic membrane lipoprotein Mext_1708 87 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 163853824 Common - PAS sensor protein Mext_4428 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163853798 Common - beta-lactamase Mext_4402 138 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 163849690 Common - response regulator receiver Mext_0237 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163853872 Common - hypothetical protein Mext_4476 5 None None None 163849919 Common - hypothetical protein Mext_0470 81 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 163850305 Nonpathogen - hypothetical protein Mext_0872 1 COG5373 COG5373, Predicted membrane protein Function unknown 163851413 Nonpathogen - hypothetical protein Mext_1986 1 None None None 163852562 Common - Alcohol dehydrogenase zinc-binding domain protein Mext_3146 186 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 163853960 Nonpathogen - hypothetical protein Mext_4564 1 None None None 163850638 Common - phospholipase/Carboxylesterase Mext_1208 25 COG0400 COG0400, Predicted esterase General function prediction only 163852522 Common - methyltransferase small Mext_3106 66 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 163853512 Common - response regulator receiver Mext_4114 208 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163853303 Common - Nicotinamidase Mext_3904 125 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 163852313 Nonpathogen - hypothetical protein Mext_2895 1 None None None 163853054 Common - Organic solvent tolerance protein Mext_3648 118 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 163851331 Common - Mg chelatase, subunit ChlI Mext_1904 186 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 163853251 Nonpathogen - hypothetical protein Mext_3851 1 None None None 163850860 Common - phage major capsid protein, HK97 family Mext_1431 52 COG4653 COG4653, Predicted phage phi-C31 gp36 major capsid-like protein General function prediction only 163849679 Nonpathogen - caa(3)-type oxidase, subunit IV Mext_0225 3 None None None 163853693 Common - response regulator receiver Mext_4296 48 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163850321 Common - hypothetical protein Mext_0888 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 163853208 Common - regulatory protein LysR Mext_3806 56 COG1910 COG1910, Periplasmic molybdate-binding protein/domain Inorganic ion transport and metabolism 163853576 Common - short-chain dehydrogenase/reductase SDR Mext_4179 217 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 163850012 Common - ABC transporter related Mext_0569 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 163850329 Common - hypothetical protein Mext_0896 6 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 163851282 Nonpathogen - hypothetical protein Mext_1855 1 None None None 163851816 Common - dTDP-glucose 4,6-dehydratase Mext_2393 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 163849713 Nonpathogen - hypothetical protein Mext_0261 1 None None None 163851299 Nonpathogen - hypothetical protein Mext_1872 1 None None None 163852217 Common - cell wall hydrolase SleB Mext_2798 27 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 163851249 Common - ATP-binding region ATPase domain protein Mext_1822 214 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 163851561 Common - fumarylacetoacetate (FAA) hydrolase Mext_2138 170 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 163852923 Common - ATP-binding region ATPase domain protein Mext_3510 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163850460 Nonpathogen - hypothetical protein Mext_1027 1 None None None 163850143 Common - major facilitator superfamily MFS_1 Mext_0703 62 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163853478 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mext_4080 226 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 163853679 Common - DNA mismatch repair protein MutS Mext_4282 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 163853000 Nonpathogen - hypothetical protein Mext_3594 1 None None None 163852421 Common - tRNA synthetase class II (D K and N) Mext_3004 204 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 163850742 Common - transposase-like protein Mext_1313 9 None None None 163850667 Common - ATP-binding region ATPase domain protein Mext_1237 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163852208 Common - pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase Mext_2789 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 163850796 Common - cellulose synthase catalytic subunit (UDP-forming) Mext_1367 128 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163850444 Common - hypothetical protein Mext_1011 12 None None None 163850233 Common - zinc-containing alcohol dehydrogenase superfamily Mext_0799 14 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 163854147 Common - 3-demethylubiquinone-9 3-methyltransferase Mext_4751 65 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 163850751 Common - phosphoglycerate mutase 1 family Mext_1322 165 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 163852046 Nonpathogen - hypothetical protein Mext_2626 2 None None None 163849764 Common - mutator MutT protein Mext_0312 162 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 163850196 Common - beta-lactamase domain protein Mext_0756 56 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 163853348 Common - formylmethionine deformylase Mext_3949 199 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 163851204 Common - regulatory protein TetR Mext_1777 91 COG1309 AcrR, Transcriptional regulator Transcription 163851378 Common - major facilitator superfamily MFS_1 Mext_1951 128 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 163849956 Common - short chain oxidoreductase Mext_0512 11 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 163849805 Nonpathogen - hypothetical protein Mext_0355 1 None None None 163852768 Nonpathogen - hypothetical protein Mext_3353 1 None None None 163852201 Nonpathogen - putative transmembrane protein Mext_2782 1 None None None 163852842 Common - DoxX family protein Mext_3428 11 COG2259 COG2259, Predicted membrane protein Function unknown 163851715 Common - DSBA oxidoreductase Mext_2292 48 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 163852190 Common - Carbohydrate-selective porin OprB Mext_2771 20 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 163852340 Common - PepSY-associated TM helix domain protein Mext_2923 60 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 163853458 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_4060 50 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 163852518 Common - regulatory protein TetR Mext_3102 24 COG1309 AcrR, Transcriptional regulator Transcription 163852865 Common - Non-specific serine/threonine protein kinase Mext_3451 22 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 163853932 Common - Saccharopine dehydrogenase Mext_4536 24 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 163853407 Common - 5-oxopent-3-ene-1,2,5-tricarboxylate decarboxylase Mext_4008 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 163853544 Common - methanol dehydrogenase beta subunit Mext_4147 7 None None None 163850631 Common - protein of unknown function DUF1624 Mext_1201 23 COG3503 COG3503, Predicted membrane protein Function unknown 163851058 Common - SEC-C motif domain protein Mext_1631 49 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 163851750 Nonpathogen - hypothetical protein Mext_2327 6 None None None 163853907 Common - glycosyl transferase group 1 Mext_4511 99 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163853682 Common - hypothetical protein Mext_4285 5 None None None 163851049 Common - hypothetical protein Mext_1622 52 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163850114 Common - conserved hypothetical protein; putative deoxyribonuclease Mext_0674 101 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 163851909 Common - MaoC domain protein dehydratase Mext_2486 62 COG2030 MaoC, Acyl dehydratase Lipid metabolism 163851222 Common - Serine--glyoxylate transaminase Mext_1795 157 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 163849860 Common - binding-protein-dependent transport systems inner membrane component Mext_0410 98 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 163850717 Common - Extracellular ligand-binding receptor Mext_1288 136 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 163854239 Common - peptidoglycan-associated lipoprotein Mext_4843 142 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 163853883 Nonpathogen - hypothetical protein Mext_4487 1 None None None 163849742 Common - methylmalonyl-CoA mutase, large subunit Mext_0290 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 163851080 Common - Sarcosine oxidase delta subunit heterotetrameric Mext_1653 33 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 163852149 Common - chlorophyllide reductase iron protein subunit X Mext_2730 70 COG1348 NifH, Nitrogenase subunit NifH (ATPase) Inorganic ion transport and metabolism 163853668 Common - protein of unknown function DUF336 Mext_4271 27 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 163853314 Nonpathogen - hypothetical protein Mext_3915 1 COG5373 COG5373, Predicted membrane protein Function unknown 163850261 Common - Acetamidase/Formamidase Mext_0828 65 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 163852125 Nonpathogen - hypothetical protein Mext_2706 3 None None None 163851631 Common - protein of unknown function DUF404 Mext_2208 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 163853154 Common - amidase, hydantoinase/carbamoylase family Mext_3752 86 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 163850268 Common - (2Fe-2S)-binding domain protein Mext_0835 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 163850944 Common - plasmid stabilization system Mext_1517 30 COG3668 ParE, Plasmid stabilization system protein General function prediction only 163850244 Common - helicase domain protein Mext_0811 83 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 163852594 Nonpathogen - hypothetical protein Mext_3179 1 None None None 163851087 Nonpathogen - hypothetical protein Mext_1660 1 None None None 163852745 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Mext_3330 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 163851213 Common - protein of unknown function DUF1234 Mext_1786 51 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 163853080 Common - periplasmic glucan biosynthesis protein MdoG Mext_3674 50 COG3131 MdoG, Periplasmic glucans biosynthesis protein Inorganic ion transport and metabolism 163851191 Nonpathogen - hypothetical protein Mext_1764 7 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 163854281 Common - Resolvase domain Mext_4885 108 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 163851674 Common - Thioredoxin domain Mext_2251 222 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 163852382 Common - deoxyribose-phosphate aldolase Mext_2965 136 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 163851823 Common - GAF domain protein Mext_2400 46 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163852823 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Mext_3409 99 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163853502 Common - acyl-CoA dehydrogenase domain protein Mext_4104 154 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 163849708 Nonpathogen - hypothetical protein Mext_0256 1 None None None 163851280 Common - TonB-dependent receptor Mext_1853 44 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 163852281 Common - cell division ATP-binding protein FtsE Mext_2863 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 163852235 Common - 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Mext_2817 194 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 163851185 Common - hypothetical protein Mext_1758 19 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 163854079 Common - LexA repressor Mext_4683 171 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 163853715 Common - methylated-DNA--protein-cysteine methyltransferase Mext_4318 196 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 163851074 Common - 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase Mext_1647 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 163851389 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Mext_1962 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 163850722 Common - amidase, hydantoinase/carbamoylase family Mext_1293 85 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 163851916 Nonpathogen - BA14K family protein Mext_2493 4 None None None 163852349 Nonpathogen - phosphoesterase PA-phosphatase related Mext_2932 1 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 163849664 Common - (2Fe-2S)-binding domain protein Mext_0210 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 163851238 Common - extracellular solute-binding protein family 3 Mext_1811 18 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 163852720 Common - helix-turn-helix domain protein Mext_3305 33 COG1396 HipB, Predicted transcriptional regulators Transcription 163851617 Nonpathogen - hypothetical protein Mext_2194 1 None None None 163853619 Common - protein of unknown function DUF983 Mext_4222 26 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 163850673 Common - putative transcriptional regulator lacI family Mext_1243 7 COG1609 PurR, Transcriptional regulators Transcription 163850772 Nonpathogen - hypothetical protein Mext_1343 1 None None None 163854242 Common - hypothetical protein Mext_4846 2 None None None 163853898 Common - transaldolase Mext_4502 204 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 163851848 Nonpathogen - hypothetical protein Mext_2425 1 None None None 163851771 Common - short chain fatty acid transporter Mext_2348 39 COG2031 AtoE, Short chain fatty acids transporter Lipid metabolism 163850458 Common - glutamyl-tRNA synthetase class Ic Mext_1025 240 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 163852587 Nonpathogen - H+transporting two-sector ATPase B/B' subunit Mext_3172 1 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 163851793 Common - thiamine monophosphate synthase Mext_2370 20 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 163850153 Common - histone deacetylase superfamily Mext_0713 149 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 163852639 Common - electron transport protein SCO1/SenC Mext_3224 108 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 163850167 Common - Putative ParB-like nuclease Mext_0727 16 COG4318 COG4318, Uncharacterized protein conserved in bacteria Function unknown 163853168 Nonpathogen - hypothetical protein Mext_3766 4 None None None 163850648 Common - GntR domain protein Mext_1218 123 COG1802 GntR, Transcriptional regulators Transcription 163850375 Common - heat shock protein DnaJ domain protein Mext_0942 67 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 163852244 Common - sulphate transporter Mext_2826 151 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 163853765 Common - ThiJ/PfpI domain protein Mext_4368 121 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 163851911 Common - OsmC family protein Mext_2488 96 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 163853813 Common - hypothetical protein Mext_4417 68 COG3176 COG3176, Putative hemolysin General function prediction only 163850822 Nonpathogen - Peptidoglycan-binding domain 1 protein Mext_1393 4 None None None 163851002 Common - cyclic nucleotide-binding Mext_1575 12 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163851610 Common - ribosomal protein S8 Mext_2187 235 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 163854208 Common - magnesium protoporphyrin O-methyltransferase Mext_4812 25 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 163849751 Common - protein of unknown function DUF900 hydrolase family protein Mext_0299 24 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 163849703 Common - NAD-dependent epimerase/dehydratase Mext_0250 226 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 163852491 Nonpathogen - hypothetical protein Mext_3074 6 None None None 163852879 Common - ribosomal protein L32 Mext_3466 119 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 163853024 Nonpathogen - hypothetical protein Mext_3618 1 None None None 163853664 Common - ABC transporter related Mext_4267 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 163853560 Common - transcription-repair coupling factor Mext_4163 216 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 163850231 Nonpathogen - hypothetical protein Mext_0797 2 None None None 163850042 Common - adenine phosphoribosyltransferase Mext_0600 195 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 163851431 Common - hypothetical protein Mext_2004 30 None None None 163850558 Common - Platelet-activating factor acetylhydrolase plasma/intracellular isoform II Mext_1126 17 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 163851104 Common - LysR substrate-binding Mext_1677 140 COG0583 LysR, Transcriptional regulator Transcription 163850124 Common - flagellar hook-associated protein FlgK Mext_0684 35 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 163853421 Common - helix-turn-helix HxlR type Mext_4023 142 COG1733 COG1733, Predicted transcriptional regulators Transcription 163854126 Common - 3-hydroxybutyrate dehydrogenase Mext_4730 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163852777 Common - response regulator receiver Mext_3363 112 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163853994 Nonpathogen - hypothetical protein Mext_4598 1 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163851894 Common - DNA polymerase I Mext_2471 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 163853116 Common - Glutathione S-transferase domain Mext_3713 62 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163850803 Common - hypothetical protein Mext_1374 12 None None None 163853891 Common - nitrate ABC transporter, inner membrane subunit Mext_4495 195 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163851951 Common - Polyprenyl synthetase Mext_2529 237 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 163852352 Nonpathogen - hypothetical protein Mext_2935 1 None None None 163849468 Common - phosphoribosylformylglycinamidine synthase II Mext_0011 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 163850410 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mext_0977 234 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 163850415 Common - protein of unknown function DUF28 Mext_0982 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 163853596 Common - major facilitator superfamily MFS_1 Mext_4199 182 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 163853143 Nonpathogen - hypothetical protein Mext_3741 1 None None None 163851063 Common - peptide deformylase Mext_1636 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 163852527 Common - Tetratricopeptide TPR_2 repeat protein Mext_3111 125 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 163849618 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_0164 31 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163852819 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Mext_3405 83 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163850348 Common - PAS sensor protein Mext_0915 113 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163850610 Common - transcriptional regulator, LysR family Mext_1180 23 None None None 163851465 Common - protein of unknown function DUF820 Mext_2041 21 COG4636 Uma2, Uncharacterized protein conserved in cyanobacteria Function unknown 163853808 Common - GCN5-related N-acetyltransferase Mext_4412 95 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 163849858 Common - Substrate-binding region of ABC-type glycine betaine transport system Mext_0408 84 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 163852308 Nonpathogen - hypothetical protein Mext_2890 1 None None None 163850173 Common - uroporphyrinogen III synthase HEM4 Mext_0733 27 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 163852005 Common - ATP-binding region ATPase domain protein Mext_2584 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163853018 Common - short-chain dehydrogenase/reductase SDR Mext_3612 220 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163850480 Common - ABC-3 protein Mext_1047 111 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 163850105 Common - putative DNA-binding protein Mext_0663 13 None None None 163853327 Common - 2-polyprenylphenol 6-hydroxylase Mext_3928 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 163849670 Common - 4Fe-4S ferredoxin iron-sulfur binding domain protein Mext_0216 136 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 163850592 Common - type I secretion membrane fusion protein, HlyD family Mext_1162 113 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163850975 Common - transposase IS116/IS110/IS902 family protein Mext_1548 83 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 163850497 Common - ABC transporter related Mext_1064 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 163851142 Common - FAD linked oxidase domain protein Mext_1715 69 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 163854189 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Mext_4793 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 163852962 Common - asparagine synthase (glutamine-hydrolyzing) Mext_3554 169 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 163852854 Common - hypothetical protein Mext_3440 19 COG4704 COG4704, Uncharacterized protein conserved in bacteria Function unknown 163850391 Common - aspartate kinase Mext_0958 233 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 163849526 Common - hypothetical protein Mext_0070 7 None None None 163850641 Common - major facilitator superfamily MFS_1 Mext_1211 79 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 163852892 Common - regulatory protein LysR Mext_3479 49 COG1910 COG1910, Periplasmic molybdate-binding protein/domain Inorganic ion transport and metabolism 163851902 Common - Flp pilus assembly protein CpaB Mext_2479 52 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 163851990 Common - Rhodanese domain protein Mext_2568 145 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 163850788 Common - ABC transporter related Mext_1359 89 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 163852630 Nonpathogen - hypothetical protein Mext_3215 1 None None None 163852995 Nonpathogen - hypothetical protein Mext_3589 4 None None None 163852947 Nonpathogen - hypothetical protein Mext_3536 1 None None None 163850282 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Mext_0849 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 163853487 Common - flagellar motor switch protein FliN Mext_4089 83 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 163853633 Common - hypothetical protein Mext_4236 8 None None None 163854116 Common - Domain of unknown function DUF1849 Mext_4720 19 None None None 163852943 Common - transposase IS116/IS110/IS902 family protein Mext_3532 80 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 163852039 Common - ribosomal protein L13 Mext_2619 220 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 163849825 Common - sugar fermentation stimulation protein Mext_0375 102 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 163850934 Common - Rubrerythrin Mext_1505 24 COG1633 COG1633, Uncharacterized conserved protein Function unknown 163852582 Nonpathogen - hypothetical protein Mext_3166 1 None None None 163853837 Common - glucose sorbosone dehydrogenase Mext_4441 119 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 163852484 Nonpathogen - hypothetical protein Mext_3067 1 None None None 163850785 Nonpathogen - cytochrome c class I Mext_1356 9 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 163851778 Common - ribosomal protein L31 Mext_2355 101 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 163852372 Nonpathogen - hypothetical protein Mext_2955 1 None None None 163849552 Common - cytochrome c oxidase, subunit II Mext_0096 158 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 163853276 Common - transcription elongation factor GreA/GreB domain protein Mext_3876 124 COG0782 GreA, Transcription elongation factor Transcription 163851736 Nonpathogen - hypothetical protein Mext_2313 1 None None None 163852368 Common - putative lipoprotein Mext_2951 132 COG4105 ComL, DNA uptake lipoprotein General function prediction only 163853856 Nonpathogen - hypothetical protein Mext_4460 1 None None None 163850654 Common - monooxygenase FAD-binding Mext_1224 27 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 163853138 Common - sarcosine oxidase, beta subunit family Mext_3736 113 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 163854276 Nonpathogen - hypothetical protein Mext_4880 1 None None None 163852492 Nonpathogen - hypothetical protein Mext_3075 6 None None None 163853772 Common - peptide chain release factor 3 Mext_4375 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 163851457 Common - glycosyl transferase family 4 Mext_2033 39 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 163853849 Common - response regulator receiver Mext_4453 189 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163849472 Common - SMP-30/Gluconolaconase/LRE domain protein Mext_0015 71 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 163850842 Nonpathogen - hypothetical protein Mext_1413 1 None None None 163853200 Common - acriflavin resistance protein Mext_3798 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163852354 Nonpathogen - hypothetical protein Mext_2937 1 None None None 163853026 Common - 4-oxalocrotonate tautomerase Mext_3620 15 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 163852610 Nonpathogen - hypothetical protein Mext_3195 1 None None None 163853971 Common - hypothetical protein Mext_4575 62 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 163851153 Common - LysR substrate-binding Mext_1726 153 COG0583 LysR, Transcriptional regulator Transcription 163851834 Common - Methyltransferase type 11 Mext_2411 46 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163852179 Common - PntAB, NAD(P) transhydrogenase, alpha2 subunit Mext_2760 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 163852642 Nonpathogen - hypothetical protein Mext_3227 1 None None None 163850979 Nonpathogen - protein of unknown function DUF1469 Mext_1552 1 None None None 163851697 Common - Ribonuclease III Mext_2274 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 163852055 Common - heme exporter protein CcmA Mext_2635 243 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 163853264 Common - regulatory protein ArsR Mext_3864 54 COG0640 ArsR, Predicted transcriptional regulators Transcription 163850523 Common - protein of unknown function DUF1022 Mext_1091 21 COG3660 COG3660, Predicted nucleoside-diphosphate-sugar epimerase Cell envelope biogenesis, outer membrane 163850570 Common - protein of unknown function DUF344 Mext_1138 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 163850626 Common - urease, gamma subunit Mext_1196 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 163850370 Nonpathogen - hypothetical protein Mext_0937 4 None None None 163849587 Common - sigma-70 region 2 domain protein Mext_0132 64 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 163850080 Common - flagellar motor switch protein FliG Mext_0638 123 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 163852019 Common - Helix-turn-helix type 11 domain protein Mext_2599 87 COG2378 COG2378, Predicted transcriptional regulator Transcription 163852068 Common - hypothetical protein Mext_2648 4 COG3798 COG3798, Uncharacterized protein conserved in bacteria Function unknown 163853614 Common - PAS sensor protein Mext_4217 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163853845 Common - metal-dependent phosphohydrolase HD sub domain Mext_4449 124 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 163852953 Nonpathogen - hypothetical protein Mext_3542 1 None None None 163850761 Common - protein of unknown function DUF1194 Mext_1332 14 None None None 163850711 Common - methylmalonate-semialdehyde dehydrogenase Mext_1282 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 163851240 Common - dihydroneopterin aldolase Mext_1813 77 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 163853431 Common - outer membrane lipoprotein carrier protein LolA Mext_4033 38 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 163852916 Nonpathogen - hypothetical protein Mext_3503 1 None None None 163850603 Common - Cupin 2 conserved barrel domain protein Mext_1173 30 COG4101 COG4101, Predicted mannose-6-phosphate isomerase Carbohydrate transport and metabolism 163850139 Nonpathogen - Peptidoglycan-binding domain 1 protein Mext_0699 7 None None None 163850946 Common - hypothetical protein Mext_1519 17 None None None 163852475 Common - glutathione-dependent formaldehyde-activating GFA Mext_3058 72 COG3791 COG3791, Uncharacterized conserved protein Function unknown 163851279 Common - hypothetical protein Mext_1852 10 None None None 163850518 Common - SCP-like extracellular Mext_1086 17 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 163851843 Nonpathogen - hypothetical protein Mext_2420 1 None None None 163851043 Nonpathogen - TonB family protein Mext_1616 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 163849886 Common - PAS sensor protein Mext_0436 121 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163849990 Nonpathogen - hypothetical protein Mext_0547 1 None None None 163853161 Common - RNA polymerase sigma factor, sigma-70 family Mext_3759 103 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 163853394 Common - 2'-5' RNA ligase Mext_3995 94 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 163852870 Common - hopanoid biosynthesis associated protein HpnK Mext_3456 51 COG3394 COG3394, Uncharacterized protein conserved in bacteria Function unknown 163852334 Common - Serine-type D-Ala-D-Ala carboxypeptidase Mext_2917 155 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 163851028 Common - methionine synthase Mext_1601 176 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 163854113 Common - phosphate transport system regulatory protein PhoU Mext_4717 200 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 163849567 Common - nuclease (SNase domain protein) Mext_0111 71 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 163851958 Common - sulfatase Mext_2536 26 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 163852719 Nonpathogen - hypothetical protein Mext_3304 6 None None None 163849760 Nonpathogen - hypothetical protein Mext_0308 1 None None None 163854234 Common - phosphoglucosamine mutase Mext_4838 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 163850531 Common - hypothetical protein Mext_1099 10 None None None 163850103 Nonpathogen - hypothetical protein Mext_0661 1 None None None 163853196 Nonpathogen - DoxX family protein Mext_3794 1 None None None 163853700 Common - dihydroorotase, multifunctional complex type Mext_4303 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 163854205 Nonpathogen - putative photosynthetic complex assembly protein Mext_4809 9 None None None 163851406 Nonpathogen - hypothetical protein Mext_1979 1 None None None 163852137 Common - HhH-GPD family protein Mext_2718 212 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 163852795 Common - ABC transporter substrate-binding protein Mext_3381 118 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 163851668 Common - conserved hypothetical protein; putative secreted protein Mext_2245 13 None None None 163851250 Nonpathogen - hypothetical protein Mext_1823 5 None None None 163853441 Common - small GTP-binding protein Mext_4043 228 COG1160 COG1160, Predicted GTPases General function prediction only 163850574 Common - protein of unknown function DUF395 YeeE/YedE Mext_1143 59 COG2391 COG2391, Predicted transporter component General function prediction only 163854026 Common - hypothetical protein Mext_4630 13 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 163852580 Common - GtrA family protein Mext_3164 12 COG2246 COG2246, Predicted membrane protein Function unknown 163850682 Common - hypothetical protein Mext_1252 11 None None None 163853591 Common - ABC transporter related Mext_4194 248 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 163849927 Nonpathogen - hypothetical protein Mext_0482 1 None None None 163851306 Nonpathogen - hypothetical protein Mext_1879 1 None None None 163854088 Common - protease Do Mext_4692 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 163849692 Common - TRAP-type uncharacterized transport system periplasmic component-like protein Mext_0239 45 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 163849479 Common - GntR domain protein Mext_0022 134 COG1802 GntR, Transcriptional regulators Transcription 163853375 Common - aminotransferase class V Mext_3976 226 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 163852606 Common - dihydrodipicolinate synthase Mext_3191 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 163851629 Common - methionine aminopeptidase, type I Mext_2206 241 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 163849578 Common - integrase, catalytic region Mext_0122 32 None None None 163850897 Common - ATP synthase F1, alpha subunit Mext_1468 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 163849559 Nonpathogen - hypothetical protein Mext_0103 1 None None None 163851888 Common - hypothetical protein Mext_2465 57 COG3665 COG3665, Uncharacterized conserved protein Function unknown 163850707 Common - binding-protein-dependent transport systems inner membrane component Mext_1278 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 163849623 Common - hypothetical protein Mext_0169 3 None None None 163852423 Common - protein of unknown function DUF1624 Mext_3006 15 COG3503 COG3503, Predicted membrane protein Function unknown 163853452 Nonpathogen - hypothetical protein Mext_4054 1 None None None 163852725 Common - putative transmembrane b-type cytochrome protein Mext_3310 25 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 163852825 Common - pyridine nucleotide-disulfide oxidoreductase family Mext_3411 30 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 163853755 Common - efflux transporter, RND family, MFP subunit Mext_4358 129 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163854070 Common - molybdenum cofactor synthesis domain protein Mext_4674 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 163852629 Nonpathogen - hypothetical protein Mext_3214 1 None None None 163853244 Common - ABC transporter related Mext_3844 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 163852730 Common - DNA protecting protein DprA Mext_3315 206 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 163851395 Nonpathogen - hypothetical protein Mext_1968 1 None None None 163853556 Common - protein of unknown function DUF502 Mext_4159 79 COG2928 COG2928, Uncharacterized conserved protein Function unknown 163851692 Common - protein of unknown function DUF214 Mext_2269 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 163854105 Nonpathogen - hypothetical protein Mext_4709 4 None None None 163852034 Common - periplasmic protein thiol--disulphide oxidoreductase DsbE Mext_2614 142 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 163854254 Nonpathogen - hypothetical protein Mext_4858 1 None None None 163852405 Common - protein of unknown function UPF0075 Mext_2988 121 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 163850542 Common - NADH:flavin oxidoreductase/NADH oxidase Mext_1110 177 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 163852089 Common - pyridoxal kinase Mext_2670 61 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 163851853 Nonpathogen - hypothetical protein Mext_2430 1 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 163853605 Common - ISHne3, transposase Mext_4208 40 None None None 163852835 Nonpathogen - hypothetical protein Mext_3421 4 None None None 163850710 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mext_1281 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 163851818 Common - glucose-1-phosphate thymidylyltransferase Mext_2395 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 163852105 Common - LmbE family protein Mext_2686 8 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 163851656 Common - sulfate adenylyltransferase, small subunit Mext_2233 136 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 163853608 Common - lipoate-protein ligase B Mext_4211 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 163849723 Common - putative restriction endonuclease Mext_0271 31 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 163850829 Common - Vault protein inter-alpha-trypsin domain protein Mext_1400 43 COG2425 COG2425, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 163853526 Common - lipopolysaccharide biosynthesis protein Mext_4129 55 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 163852130 Common - malto-oligosyltrehalose synthase Mext_2711 165 COG3280 TreY, Maltooligosyl trehalose synthase Carbohydrate transport and metabolism 163852023 Common - flagellar biosynthetic protein FlhB Mext_2603 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 163849637 Common - RNA methyltransferase, TrmH family, group 3 Mext_0183 212 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 163849773 Nonpathogen - hypothetical protein Mext_0321 1 None None None 163853724 Common - sugar isomerase (SIS) Mext_4327 92 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 163849648 Nonpathogen - hypothetical protein Mext_0194 1 None None None 163851341 Common - transcriptional regulator, ArsR family Mext_1914 64 COG0640 ArsR, Predicted transcriptional regulators Transcription 163853131 Common - binding-protein-dependent transport systems inner membrane component Mext_3729 188 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163849598 Nonpathogen - hypothetical protein Mext_0143 10 None None None 163853638 Common - Arginyltransferase Mext_4241 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 163854100 Nonpathogen - hypothetical protein Mext_4704 1 None None None 163853811 Common - protein of unknown function DUF853 NPT hydrolase putative Mext_4415 77 COG0433 COG0433, Predicted ATPase General function prediction only 163851037 Common - thiamine biosynthesis protein ThiC Mext_1610 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 163851592 Common - ribosomal protein L16 Mext_2169 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 163849616 Common - hypothetical protein Mext_0162 18 None None None 163852903 Common - putative monooxygenase Mext_3490 66 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 163850474 Common - helix-turn-helix domain protein Mext_1041 41 COG1396 HipB, Predicted transcriptional regulators Transcription 163853491 Common - protein of unknown function DUF1153 Mext_4093 27 None None None 163852012 Common - potassium efflux system protein Mext_2592 163 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 163852387 Common - Three-deoxy-D-manno-octulosonic-acid transferase domain protein Mext_2970 127 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 163853255 Common - efflux transporter, RND family, MFP subunit Mext_3855 165 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163849993 Nonpathogen - protein of unknown function DUF1674 Mext_0550 1 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 163851422 Common - regulatory protein LuxR Mext_1995 9 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 163852440 Common - hypothetical protein Mext_3023 23 COG2351 COG2351, Transthyretin-like protein General function prediction only 163853032 Common - short-chain dehydrogenase/reductase SDR Mext_3626 73 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 163851254 Common - tungsten-containing formylmethanofuran dehydrogenase, subunit B Mext_1827 8 COG1029 FwdB, Formylmethanofuran dehydrogenase subunit B Energy production and conversion 163849718 Common - helix-turn-helix HxlR type Mext_0266 135 COG1733 COG1733, Predicted transcriptional regulators Transcription 163853039 Common - molybdate ABC transporter, inner membrane subunit Mext_3633 220 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 163852398 Nonpathogen - hypothetical protein Mext_2981 4 None None None 163851442 Nonpathogen - protein of unknown function DUF466 Mext_2016 1 COG2879 COG2879, Uncharacterized small protein Function unknown 163850091 Nonpathogen - hypothetical protein Mext_0649 1 None None None 163849628 Nonpathogen - putative transmembrane protein Mext_0174 3 None None None 163853574 Common - Cyclohexanone monooxygenase Mext_4177 58 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 163853308 Common - addiction module toxin, RelE/StbE family Mext_3909 20 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 163850678 Nonpathogen - flagellar FlbT family protein Mext_1248 16 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 163853826 Common - Nucleotidyl transferase Mext_4430 180 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 163853530 Common - NAD-dependent epimerase/dehydratase Mext_4133 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163853366 Nonpathogen - hypothetical protein Mext_3967 1 None None None 163850188 Common - alpha/beta hydrolase fold Mext_0748 78 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163849814 Nonpathogen - CsbD family protein Mext_0364 9 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 163851874 Common - Resolvase domain Mext_2451 43 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 163852232 Common - molybdopterin dehydrogenase FAD-binding Mext_2814 57 COG1319 CoxM, Aerobic-type carbon monoxide dehydrogenase, middle subunit CoxM/CutM homologs Energy production and conversion 163850887 Common - protein of unknown function DUF58 Mext_1458 62 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 163850618 Common - hypothetical protein Mext_1188 8 None None None 163852932 Nonpathogen - hypothetical protein Mext_3520 1 None None None 163849839 Common - molybdopterin oxidoreductase Mext_0389 189 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 163850671 Common - efflux transporter, RND family, MFP subunit Mext_1241 165 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163850294 Common - MgtC/SapB transporter Mext_0861 41 COG1285 SapB, Uncharacterized membrane protein Function unknown 163851586 Common - ribosomal protein L4/L1e Mext_2163 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 163850074 Common - putative chemotaxis protein precursor Mext_0632 11 None None None 163853051 Common - LrgA family protein Mext_3645 36 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 163854221 Common - Gluconate 2-dehydrogenase (acceptor) Mext_4825 75 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 163849935 Nonpathogen - hypothetical protein Mext_0491 1 None None None 163850657 Common - LmbE family protein Mext_1227 35 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 163851001 Common - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase Mext_1574 157 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 163851948 Nonpathogen - hypothetical protein Mext_2526 1 None None None 163853074 Nonpathogen - hypothetical protein Mext_3668 1 None None None 163850984 Nonpathogen - hypothetical protein Mext_1557 1 None None None 163852361 Common - hypothetical protein Mext_2944 9 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 163849823 Common - putative transport protein, YfdC-like protein Mext_0373 56 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 163851449 Common - 2,5-didehydrogluconate reductase Mext_2023 171 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 163851765 Common - acetylglutamate kinase Mext_2342 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 163853985 Common - lipopolysaccharide biosynthesis protein Mext_4589 47 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 163852380 Nonpathogen - conserved hypothetical protein; putative secreted protein Mext_2963 1 None None None 163851114 Common - zinc-binding alcohol dehydrogenase family protein Mext_1687 128 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 163851106 Common - Alcohol dehydrogenase zinc-binding domain protein Mext_1679 181 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 163852263 Common - molybdopterin binding domain Mext_2845 176 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 163853747 Common - LysR substrate-binding Mext_4350 182 COG0583 LysR, Transcriptional regulator Transcription 163851533 Common - hypothetical protein Mext_2110 19 None None None 163853108 Nonpathogen - hypothetical protein Mext_3704 1 None None None 163854093 Common - protein-L-isoaspartate(D-aspartate) O-methyltransferase Mext_4697 161 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 163849482 Common - malonate decarboxylase, beta subunit Mext_0026 168 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 163849534 Nonpathogen - hypothetical protein Mext_0078 2 None None None 163850740 Common - putative ABC-type Co2+ transport system, periplasmic component Mext_1311 14 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 163851290 Common - hypothetical protein Mext_1863 3 None None None 163852733 Common - ThiJ/PfpI domain protein Mext_3318 83 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 163851540 Common - Histidine kinase Mext_2117 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163850250 Common - hypothetical protein Mext_0817 6 None None None 163853508 Common - Non-specific serine/threonine protein kinase Mext_4110 80 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 163850337 Common - NUDIX hydrolase Mext_0904 158 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 163850587 Common - Nitrilase Mext_1157 78 COG0388 COG0388, Predicted amidohydrolase General function prediction only 163852192 Common - hypothetical protein Mext_2773 4 COG3794 PetE, Plastocyanin Energy production and conversion 163853817 Nonpathogen - hypothetical protein Mext_4421 2 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 163849493 Common - YidE/YbjL duplication Mext_0037 43 COG2985 COG2985, Predicted permease General function prediction only 163850549 Common - PAS sensor protein Mext_1117 132 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163852789 Common - Formamidase Mext_3375 62 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 163851883 Common - integrase family protein Mext_2460 100 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163852654 Common - protein of unknown function DUF606 Mext_3239 41 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 163854167 Common - GCN5-related N-acetyltransferase Mext_4771 152 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 163853882 Nonpathogen - hypothetical protein Mext_4486 4 None None None 163850330 Common - 4-hydroxybenzoate polyprenyl transferase Mext_0897 169 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 163853969 Common - response regulator receiver Mext_4573 105 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163852860 Common - metallophosphoesterase Mext_3446 26 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 163853876 Common - peptidase M24 Mext_4480 237 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 163851247 Nonpathogen - coenzyme PQQ biosynthesis protein A Mext_1820 1 None None None 163852323 Nonpathogen - hypothetical protein Mext_2906 1 None None None 163850502 Common - beta-lactamase domain protein Mext_1070 157 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 163852867 Common - toluene tolerance family protein Mext_3453 26 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 163851369 Common - squalene synthase HpnD Mext_1942 105 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 163850145 Common - helix-turn-helix HxlR type Mext_0705 109 COG1733 COG1733, Predicted transcriptional regulators Transcription 163851183 Common - phospholipid/glycerol acyltransferase Mext_1756 150 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 163853476 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_4078 45 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 163849894 Nonpathogen - hypothetical protein Mext_0444 4 None None None 163851716 Common - Argininosuccinate synthase Mext_2293 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 163849734 Common - carboxyl transferase Mext_0282 210 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 163853347 Nonpathogen - hypothetical protein Mext_3948 1 None None None 163851707 Common - NUDIX hydrolase Mext_2284 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 163852183 Common - HWE histidine kinase Mext_2764 31 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163854041 Common - PfkB domain protein Mext_4645 131 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 163849906 Nonpathogen - protein of unknown function DUF1236 Mext_0457 5 None None None 163854062 Common - Triose-phosphate isomerase Mext_4666 217 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 163853061 Common - DSBA oxidoreductase Mext_3655 103 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 163851578 Nonpathogen - hypothetical protein Mext_2155 1 None None None 163851781 Nonpathogen - hypothetical protein Mext_2358 2 None None None 163852157 Nonpathogen - photosynthetic reaction centre cytochrome c subunit Mext_2738 9 None None None 163849489 Nonpathogen - hypothetical protein Mext_0033 1 None None None 163850384 Common - flagellar hook-associated protein FlgK Mext_0951 120 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 163851720 Nonpathogen - hypothetical protein Mext_2297 2 None None None 163850725 Common - transcriptional regulator, LysR family Mext_1296 28 None None None 163853123 Common - allophanate hydrolase Mext_3721 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 163852761 Common - binding-protein-dependent transport systems inner membrane component Mext_3346 147 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163853490 Common - flagellar M-ring protein FliF Mext_4092 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 163853206 Common - EAL domain protein Mext_3804 171 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 163852573 Common - Chloride channel core Mext_3157 149 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 163854178 Common - chaperonin GroEL Mext_4782 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 163851623 Nonpathogen - hypothetical protein Mext_2200 1 None None None 163852676 Common - protoheme IX farnesyltransferase Mext_3261 165 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 163851688 Common - GTP cyclohydrolase I Mext_2265 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 163853045 Common - dimethyladenosine transferase Mext_3639 242 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 163850437 Common - GCN5-related N-acetyltransferase Mext_1004 3 COG3153 COG3153, Predicted acetyltransferase General function prediction only 163851069 Common - regulatory protein TetR Mext_1642 21 COG1309 AcrR, Transcriptional regulator Transcription 163851384 Nonpathogen - hypothetical protein Mext_1957 9 None None None 163853539 Common - hypothetical protein Mext_4142 7 None None None 163850401 Common - transcriptional regulator, Rrf2 family Mext_0968 154 COG1959 COG1959, Predicted transcriptional regulator Transcription 163854123 Nonpathogen - hypothetical protein Mext_4727 1 None None None 163850575 Common - regulatory protein ArsR Mext_1145 87 COG0640 ArsR, Predicted transcriptional regulators Transcription 163853942 Common - Beta-ketoacyl synthase Mext_4546 80 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163851161 Common - flavin reductase domain protein FMN-binding Mext_1734 107 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 163851260 Common - triphosphoribosyl-dephospho-CoA protein Mext_1833 16 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 163851265 Common - 40-residue YVTN family beta-propeller repeat protein Mext_1838 91 COG3391 COG3391, Uncharacterized conserved protein Function unknown 163849500 Nonpathogen - hypothetical protein Mext_0044 1 None None None 163853005 Common - sodium/sulphate symporter Mext_3599 40 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 163854228 Common - SCP-like extracellular Mext_4832 17 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 163852622 Common - CBS domain containing protein Mext_3207 216 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 163850033 Common - Invasion associated locus B family protein Mext_0591 21 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 163852885 Common - peptidase M29 aminopeptidase II Mext_3472 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 163850907 Common - preprotein translocase, SecA subunit Mext_1478 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 163853976 Nonpathogen - hypothetical protein Mext_4580 1 None None None 163851762 Nonpathogen - hypothetical protein Mext_2339 1 None None None 163850844 Nonpathogen - hypothetical protein Mext_1415 1 None None None 163850271 Common - Camphor resistance CrcB protein Mext_0838 155 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 163853181 Common - glutamine amidotransferase class-II Mext_3779 44 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 163853467 Common - glycerophosphoryl diester phosphodiesterase Mext_4069 84 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 163852487 Common - hypothetical protein Mext_3070 2 None None None 163852928 Nonpathogen - hypothetical protein Mext_3515 1 None None None 163849542 Nonpathogen - hypothetical protein Mext_0086 1 None None None 163854087 Common - chemotaxis sensory transducer Mext_4691 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163849609 Common - helix-turn-helix domain protein Mext_0155 42 COG1396 HipB, Predicted transcriptional regulators Transcription 163854008 Common - multiple resistance and pH regulation protein F Mext_4612 45 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 163851485 Common - SpoVR family protein Mext_2061 71 COG2719 SpoVR, Uncharacterized conserved protein Function unknown 163850257 Common - response regulator receiver Mext_0824 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163851434 Common - 6-phosphogluconate dehydratase Mext_2007 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 163852873 Common - hopanoid biosynthesis associated radical SAM protein HpnH Mext_3460 110 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 163850195 Common - short-chain dehydrogenase/reductase SDR Mext_0755 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163850914 Common - DNA polymerase III, epsilon subunit Mext_1485 188 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 163852221 Common - Ornithine cyclodeaminase Mext_2802 82 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 163852686 Common - protein of unknown function DUF459 Mext_3271 27 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 163853695 Nonpathogen - hypothetical protein Mext_4298 1 None None None 163852074 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Mext_2654 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 163852971 Nonpathogen - hypothetical protein Mext_3563 1 None None None 163850393 Common - PEBP family protein Mext_0960 71 COG1881 COG1881, Phospholipid-binding protein General function prediction only 163852882 Common - acetyl-CoA acetyltransferase Mext_3469 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 163853050 Common - LrgB family protein Mext_3644 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 163851268 Common - hypothetical protein Mext_1841 8 COG2457 COG2457, Uncharacterized conserved protein Function unknown 163851950 Common - putative thiol-disulphide oxidoreductase DCC Mext_2528 29 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 163852106 Common - Uracil-DNA glycosylase superfamily Mext_2687 8 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 163851910 Common - major facilitator superfamily MFS_1 Mext_2487 139 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 163851129 Common - inner-membrane translocator Mext_1702 94 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 163854014 Common - nucleotide sugar dehydrogenase Mext_4618 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 163851510 Common - ribosome recycling factor Mext_2086 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 163850598 Common - binding-protein-dependent transport systems inner membrane component Mext_1168 170 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163853157 Common - binding-protein-dependent transport systems inner membrane component Mext_3755 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 163854031 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Mext_4635 210 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 163852856 Common - hypothetical protein Mext_3442 27 COG0433 COG0433, Predicted ATPase General function prediction only 163852824 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Mext_3410 101 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163853594 Common - hypothetical protein Mext_4197 7 COG5373 COG5373, Predicted membrane protein Function unknown 163849932 Common - multimeric flavodoxin Mext_0487 72 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 163850900 Common - Methyltransferase type 11 Mext_1471 65 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 163851722 Common - hypothetical protein Mext_2299 13 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 163851992 Common - Hemolysin-type calcium-binding region Mext_2570 100 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 163853413 Common - ribosomal protein L10 Mext_4015 207 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 163850599 Common - ABC transporter substrate-binding protein Mext_1169 20 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163850778 Common - peptidase M48 Ste24p Mext_1349 7 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 163849910 Common - regulatory protein LysR Mext_0461 158 COG0583 LysR, Transcriptional regulator Transcription 163854099 Nonpathogen - hypothetical protein Mext_4703 5 None None None 163854188 Common - FAD dependent oxidoreductase Mext_4792 137 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 163852430 Common - urease accessory protein UreG Mext_3013 135 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 163850413 Common - Phosphoribulokinase Mext_0980 53 COG3954 PrkB, Phosphoribulokinase Energy production and conversion 163851495 Common - coenzyme A transferase Mext_2071 102 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 163853703 Common - metal-dependent phosphohydrolase HD sub domain Mext_4306 31 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 163853662 Common - DNA mismatch repair protein MutL Mext_4265 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 163849512 Common - alpha/beta hydrolase fold Mext_0056 119 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163851284 Common - glycosyl transferase group 1 Mext_1857 165 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163851020 Common - histidinol-phosphate aminotransferase Mext_1593 235 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 163852347 Nonpathogen - PilT protein domain protein Mext_2930 10 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 163850310 Nonpathogen - hypothetical protein Mext_0877 1 None None None 163852050 Nonpathogen - hypothetical protein Mext_2630 1 None None None 163851366 Common - deoxyxylulose-5-phosphate synthase Mext_1939 208 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 163852560 Common - RNA methyltransferase, TrmH family, group 1 Mext_3144 155 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 163849467 Common - hypothetical protein Mext_0010 16 None None None 163850342 Nonpathogen - hypothetical protein Mext_0909 4 None None None 163852044 Common - ABC transporter related Mext_2624 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 163853010 Common - succinate dehydrogenase and fumarate reductase iron-sulfur protein Mext_3604 194 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 163853763 Common - hypothetical protein Mext_4366 8 None None None 163851508 Common - phosphatidate cytidylyltransferase Mext_2084 208 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 163852945 Common - hypothetical protein Mext_3534 11 COG4733 COG4733, Phage-related protein, tail component Function unknown 163852738 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Mext_3323 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 163851772 Nonpathogen - protein of unknown function DUF423 Mext_2349 8 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 163851221 Common - metallophosphoesterase Mext_1794 67 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 163851955 Common - protein tyrosine phosphatase Mext_2533 15 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 163851060 Common - succinyl-diaminopimelate desuccinylase Mext_1633 211 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 163850931 Common - protein of unknown function DUF1044 Mext_1502 17 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 163852525 Common - 4-(cytidine 5'-diphospho)-2-C-methyl-D-erythritol kinase Mext_3109 170 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 163853015 Common - protein of unknown function DUF606 Mext_3609 52 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 163853835 Common - double-strand break repair protein AddB Mext_4439 49 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 163849540 Common - hypothetical protein Mext_0084 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 163850564 Common - protein kinase Mext_1132 152 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 163853562 Common - hypothetical protein Mext_4165 6 None None None 163849523 Nonpathogen - hypothetical protein Mext_0067 1 None None None 163851307 Common - regulatory protein Crp Mext_1880 28 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163853427 Common - amino acid permease-associated region Mext_4029 175 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 163852206 Common - Transketolase central region Mext_2787 217 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 163852268 Common - binding-protein-dependent transport systems inner membrane component Mext_2850 88 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 163851936 Common - diguanylate cyclase Mext_2513 173 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 163853613 Common - pentapeptide repeat protein Mext_4216 103 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 163850174 Common - hypothetical protein Mext_0734 8 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 163851869 Nonpathogen - hypothetical protein Mext_2446 1 None None None 163851753 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_2330 38 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 163852008 Common - branched-chain amino acid aminotransferase Mext_2587 215 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 163849917 Common - hypothetical protein Mext_0468 17 None None None 163850744 Common - glucose sorbosone dehydrogenase Mext_1315 117 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 163850296 Common - hypothetical protein Mext_0863 56 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 163852993 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_3587 46 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163851931 Common - multiple antibiotic resistance (MarC)-related protein Mext_2508 84 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 163853778 Nonpathogen - hypothetical protein Mext_4381 1 None None None 163851633 Nonpathogen - hypothetical protein Mext_2210 1 None None None 163853566 Common - ATP-binding region ATPase domain protein Mext_4169 187 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163850712 Common - carbon monoxide dehydrogenase subunit G Mext_1283 42 COG3427 COG3427, Uncharacterized conserved protein Function unknown 163851537 Nonpathogen - hypothetical protein Mext_2114 1 None None None 163853057 Common - Leucyl aminopeptidase Mext_3651 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 163852949 Nonpathogen - hypothetical protein Mext_3538 1 None None None 163850938 Common - malate--quinone oxidoreductase Mext_1509 56 COG0579 COG0579, Predicted dehydrogenase General function prediction only 163852844 Common - conserved hypothetical protein; putative exported protein Mext_3430 5 None None None 163851719 Common - phosphoglycolate phosphatase Mext_2296 136 COG0546 Gph, Predicted phosphatases General function prediction only 163852964 Common - lipopolysaccharide biosynthesis protein Mext_3556 20 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 163852743 Nonpathogen - hypothetical protein Mext_3328 1 None None None 163849600 Nonpathogen - hypothetical protein Mext_0145 1 None None None 163851018 Common - hypothetical protein Mext_1591 11 None None None 163851248 Common - response regulator receiver Mext_1821 220 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163851448 Common - PAS sensor protein Mext_2022 115 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163852291 Common - Aldose 1-epimerase Mext_2873 97 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 163850719 Common - (2Fe-2S)-binding domain protein Mext_1290 122 COG2080 CoxS, Aerobic-type carbon monoxide dehydrogenase, small subunit CoxS/CutS homologs Energy production and conversion 163851082 Common - ThiJ/PfpI domain protein Mext_1655 75 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 163851273 Common - putative exported protein of unknown function Mext_1846 21 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 163851198 Common - ribosomal protein L33 Mext_1771 126 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 163853888 Common - precorrin-3B synthase Mext_4492 167 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 163850633 Common - hypothetical protein Mext_1203 11 None None None 163851324 Nonpathogen - hypothetical protein Mext_1897 1 None None None 163851839 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Mext_2416 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 163853076 Common - luciferase family protein Mext_3670 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 163852898 Common - OsmC family protein Mext_3485 33 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 163852981 Common - Methyltransferase type 11 Mext_3574 57 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163852283 Common - protein of unknown function DUF218 Mext_2865 30 COG1434 COG1434, Uncharacterized conserved protein Function unknown 163853782 Nonpathogen - hypothetical protein Mext_4385 1 None None None 163852535 Common - DNA topoisomerase IV, B subunit Mext_3119 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 163851120 Common - amidohydrolase, AtzE family Mext_1693 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 163850396 Common - YceI family protein Mext_0963 114 COG2353 COG2353, Uncharacterized conserved protein Function unknown 163851676 Common - protein of unknown function DUF343 Mext_2253 96 COG2835 COG2835, Uncharacterized conserved protein Function unknown 163850966 Common - hypothetical protein Mext_1539 7 None None None 163853170 Common - putative transcriptional regulator, TetR family Mext_3768 13 None None None 163851219 Common - Ribonuclease H Mext_1792 214 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 163850265 Common - hypothetical protein Mext_0832 16 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163851084 Common - glutamate synthase alpha subunit domain protein Mext_1657 48 COG0070 GltB, Glutamate synthase domain 3 Amino acid transport and metabolism 163851472 Common - NADH:flavin oxidoreductase/NADH oxidase Mext_2048 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 163851734 Common - HpcH/HpaI aldolase Mext_2311 5 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 163852433 Common - urease, alpha subunit Mext_3016 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 163853066 Nonpathogen - hypothetical protein Mext_3660 1 None None None 163850373 Common - sodium/hydrogen exchanger Mext_0940 102 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 163849802 Common - transposase IS116/IS110/IS902 family protein Mext_0352 80 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 163854140 Common - hypothetical protein Mext_4744 11 None None None 163853049 Common - sulphate transporter Mext_3643 161 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 163852754 Common - oxidoreductase molybdopterin binding Mext_3339 82 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 163851089 Common - Animal haem peroxidase Mext_1662 90 COG2931 COG2931, RTX toxins and related Ca2+-binding proteins Secondary metabolites biosynthesis, transport, and catabolism 163850490 Common - molybdopterin binding domain Mext_1057 36 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 163851619 Common - hypothetical protein Mext_2196 10 None None None 163849949 Nonpathogen - hypothetical protein Mext_0505 11 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 163853310 Nonpathogen - hypothetical protein Mext_3911 1 None None None 163852115 Common - ribosome-binding factor A Mext_2696 166 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 163851130 Common - inner-membrane translocator Mext_1703 100 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 163851462 Common - protein of unknown function DUF1206 Mext_2038 20 None None None 163852258 Common - Protein-glutamate methylesterase Mext_2840 184 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 163851801 Common - NADPH-dependent FMN reductase Mext_2378 58 COG0431 COG0431, Predicted flavoprotein General function prediction only 163849973 Common - helix-turn-helix- domain containing protein AraC type Mext_0530 70 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 163852127 Common - regulatory protein TetR Mext_2708 69 COG1309 AcrR, Transcriptional regulator Transcription 163851907 Common - type II secretion system protein Mext_2484 80 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 163851694 Common - pyridoxal phosphate biosynthetic protein PdxJ Mext_2271 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 163850335 Nonpathogen - hypothetical protein Mext_0902 1 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 163850355 Nonpathogen - hypothetical protein Mext_0922 1 None None None 163849954 Common - NAD-dependent epimerase/dehydratase Mext_0510 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 163853111 Common - Acetyltransferase (isoleucine patch superfamily)-like protein Mext_3708 61 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 163852353 Common - 2-dehydropantoate 2-reductase Mext_2936 101 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 163853113 Common - glycosyl transferase group 1 Mext_3710 16 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163854282 Common - TonB-dependent siderophore receptor Mext_4886 96 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 163851052 Common - Amylo-alpha-16-glucosidase Mext_1625 53 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 163850005 Common - Kojibiose phosphorylase Mext_0562 50 COG1554 ATH1, Trehalose and maltose hydrolases (possible phosphorylases) Carbohydrate transport and metabolism 163850001 Common - acyl carrier protein Mext_0558 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163849983 Nonpathogen - hypothetical protein Mext_0540 4 None None None 163851501 Common - GCN5-related N-acetyltransferase Mext_2077 34 COG0456 RimI, Acetyltransferases General function prediction only 163850691 Common - binding-protein-dependent transport systems inner membrane component Mext_1261 197 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163853525 Nonpathogen - hypothetical protein Mext_4128 1 None None None 163854240 Nonpathogen - hypothetical protein Mext_4844 1 None None None 163850285 Common - adenosylmethionine-8-amino-7-oxononanoate aminotransferase Mext_0852 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 163850702 Common - putative dehydrogenase protein Mext_1273 22 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 163850429 Common - adenylosuccinate lyase Mext_0996 235 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 163849621 Common - hypothetical protein Mext_0167 10 COG4469 CoiA, Competence protein General function prediction only 163851790 Nonpathogen - hypothetical protein Mext_2367 1 None None None 163850116 Common - transcriptional regulator domain protein Mext_0676 101 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163853149 Common - Oxidoreductase FAD-binding domain protein Mext_3747 170 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 163853405 Common - biotin synthase Mext_4006 173 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 163852787 Common - Carbohydrate-selective porin OprB Mext_3373 11 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 163851371 Common - squalene-hopene cyclase Mext_1944 43 COG1657 SqhC, Squalene cyclase Lipid metabolism 163849570 Common - BLUF domain protein Mext_0114 38 None None None 163850118 Nonpathogen - type IV pilus assembly PilZ Mext_0678 3 None None None 163852143 Common - intracellular septation protein A Mext_2724 89 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 163850774 Nonpathogen - hypothetical protein Mext_1345 3 None None None 163853775 Nonpathogen - hypothetical protein Mext_4378 1 None None None 163851125 Common - ABC transporter related Mext_1698 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 163852569 Common - Alpha/beta hydrolase fold-3 domain protein Mext_3153 120 COG0657 Aes, Esterase/lipase Lipid metabolism 163850045 Common - thiazole biosynthesis family protein Mext_0603 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 163850661 Nonpathogen - hypothetical protein Mext_1231 6 COG4671 COG4671, Predicted glycosyl transferase General function prediction only 163849769 Nonpathogen - hypothetical protein Mext_0317 1 None None None 163851375 Common - nucleotide sugar dehydrogenase Mext_1948 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 163852395 Common - ribosomal protein L28 Mext_2978 127 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 163850229 Common - protein of unknown function DUF323 Mext_0792 110 COG1262 COG1262, Uncharacterized conserved protein Function unknown 163850522 Nonpathogen - hypothetical protein Mext_1090 1 None None None 163851725 Nonpathogen - TRAP-type uncharacterized transport system periplasmic component-like protein Mext_2302 7 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 163853580 Common - lipolytic protein G-D-S-L family Mext_4183 18 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 163853263 Common - arsenical resistance protein ArsH Mext_3863 65 COG0431 COG0431, Predicted flavoprotein General function prediction only 163851942 Common - acriflavin resistance protein Mext_2520 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163851139 Common - Creatininase Mext_1712 86 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 163852920 Common - PAS sensor protein Mext_3507 211 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163852219 Common - cyclase/dehydrase Mext_2800 102 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 163852131 Common - alpha amylase catalytic region Mext_2712 117 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 163849632 Common - hypothetical protein Mext_0178 17 None None None 163854044 Common - L-carnitine dehydratase/bile acid-inducible protein F Mext_4648 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 163852404 Common - tyrosyl-tRNA synthetase Mext_2987 216 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163851441 Common - hypothetical protein Mext_2015 27 COG4269 COG4269, Predicted membrane protein Function unknown 163852416 Common - protein of unknown function DUF599 Mext_2999 25 COG3821 COG3821, Predicted membrane protein Function unknown 163850612 Common - porin Mext_1182 14 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 163849778 Common - (Glutamate--ammonia-ligase) adenylyltransferase Mext_0326 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 163851804 Common - protein of unknown function DUF983 Mext_2381 27 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 163850066 Common - conserved hypothetical proteinn Mext_0624 11 COG3334 COG3334, Uncharacterized conserved protein Function unknown 163852191 Common - Cytochrome-c peroxidase Mext_2772 96 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 163850756 Nonpathogen - hypothetical protein Mext_1327 1 None None None 163852813 Common - twin-arginine translocation protein, TatA/E family subunit Mext_3399 30 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 163854080 Nonpathogen - protein of unknown function DUF1236 Mext_4684 6 COG4907 COG4907, Predicted membrane protein Function unknown 163849902 Nonpathogen - hypothetical protein Mext_0453 1 None None None 163849842 Nonpathogen - hypothetical protein Mext_0392 1 None None None 163850872 Common - cobalt transporter, subunit CbtA Mext_1443 16 COG5446 COG5446, Predicted integral membrane protein Function unknown 163850736 Common - urease, alpha subunit Mext_1307 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 163853118 Common - polysaccharide biosynthesis protein CapD Mext_3715 181 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163850801 Common - protein of unknown function DUF395, YeeE/YedE Mext_1372 54 None None None 163852775 Nonpathogen - hypothetical protein Mext_3361 1 None None None 163850194 Common - LysR substrate-binding Mext_0754 154 COG0583 LysR, Transcriptional regulator Transcription 163853870 Common - ROSMUCR transcriptional regulator Mext_4474 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 163851137 Nonpathogen - hypothetical protein Mext_1710 1 None None None 163853342 Common - Gentamicin 3'-N-acetyltransferase Mext_3943 8 COG0456 RimI, Acetyltransferases General function prediction only 163851828 Nonpathogen - hypothetical protein Mext_2405 2 None None None 163854249 Common - Extracellular ligand-binding receptor Mext_4853 140 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 163853697 Common - hypothetical protein Mext_4300 14 COG5451 COG5451, Predicted secreted protein Function unknown 163853756 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Mext_4359 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163849874 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA Mext_0424 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 163851612 Common - ribosomal protein L5 Mext_2189 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 163850433 Common - hypothetical protein Mext_1000 13 COG5373 COG5373, Predicted membrane protein Function unknown 163849683 Common - hypothetical protein Mext_0229 25 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 163849960 Common - ATP-binding region ATPase domain protein Mext_0517 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163850320 Nonpathogen - hypothetical protein Mext_0887 1 None None None 163850451 Common - short-chain dehydrogenase/reductase SDR Mext_1018 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163852833 Common - short-chain dehydrogenase/reductase SDR Mext_3419 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163853220 Common - hypothetical protein Mext_3818 15 None None None 163851810 Common - undecaprenol kinase Mext_2387 196 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 163849800 Common - integrase family protein Mext_0348 36 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163850863 Common - protein of unknown function DUF264 Mext_1434 25 COG5323 COG5323, Uncharacterized conserved protein Function unknown 163850164 Common - monooxygenase FAD-binding Mext_0724 64 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 163850303 Common - protein of unknown function DUF6 transmembrane Mext_0870 139 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 163853102 Nonpathogen - putative insertion sequence transposase protein Mext_3698 8 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 163850586 Common - protein of unknown function DUF485 Mext_1156 22 COG3162 COG3162, Predicted membrane protein Function unknown 163852762 Common - putative ABC transporter, substrate-binding protein Mext_3347 70 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163850790 Common - cytochrome d ubiquinol oxidase, subunit II Mext_1361 153 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 163850879 Common - formaldehyde-activating enzyme Mext_1450 26 COG1795 COG1795, Uncharacterized conserved protein Function unknown 163851385 Common - AMP-dependent synthetase and ligase Mext_1958 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 163851347 Common - TIR protein Mext_1920 17 None None None 163849840 Common - 4Fe-4S ferredoxin iron-sulfur binding domain protein Mext_0390 162 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 163853627 Common - protein of unknown function DUF815 Mext_4230 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 163849782 Common - OsmC family protein Mext_0330 27 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 163853635 Common - Porphobilinogen synthase Mext_4238 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 163854027 Common - AAA ATPase central domain protein Mext_4631 97 COG0714 COG0714, MoxR-like ATPases General function prediction only 163852640 Common - glycosyl transferase family 2 Mext_3225 90 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163849950 Nonpathogen - hypothetical protein Mext_0506 11 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 163853926 Common - hypothetical protein Mext_4530 8 None None None 163852474 Common - elongation factor G domain IV Mext_3057 242 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 163853728 Common - SNARE associated Golgi protein Mext_4331 76 COG0398 COG0398, Uncharacterized conserved protein Function unknown 163850246 Common - RNA binding S1 domain protein Mext_0813 186 COG2183 Tex, Transcriptional accessory protein Transcription 163854052 Common - DNA polymerase III chi subunit HolC Mext_4656 44 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 163853801 Common - NADH dehydrogenase (quinone) Mext_4405 165 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 163851402 Common - chemotaxis sensory transducer Mext_1975 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163852500 Common - adenylyl cyclase class-3/4/guanylyl cyclase Mext_3083 90 COG2114 CyaA, Adenylate cyclase, family 3 (some proteins contain HAMP domain) Signal transduction mechanisms 163851570 Common - Citrate (pro-3S)-lyase Mext_2147 111 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 163852649 Common - protein of unknown function DUF1275 Mext_3234 32 COG3619 COG3619, Predicted membrane protein Function unknown 163850551 Common - protein of unknown function DUF938 Mext_1119 49 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 163849847 Common - acriflavin resistance protein Mext_0397 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163851315 Common - PAS sensor protein Mext_1888 135 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163850813 Common - Carbohydrate-selective porin OprB Mext_1384 19 COG3659 OprB, Carbohydrate-selective porin Cell envelope biogenesis, outer membrane 163851046 Nonpathogen - hypothetical protein Mext_1619 6 None None None 163852464 Common - flagellar basal-body rod protein FlgG Mext_3047 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 163849586 Common - Hemolysin-type calcium-binding region Mext_0131 102 None None None 163853916 Common - acriflavin resistance protein Mext_4520 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 163853459 Nonpathogen - hypothetical protein Mext_4061 4 None None None 163849869 Common - response regulator receiver Mext_0419 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163852540 Common - PRC-barrel domain protein Mext_3124 6 None None None 163853177 Common - putative glutathione-S-transferase protein Mext_3775 63 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163853965 Common - pantetheine-phosphate adenylyltransferase Mext_4569 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 163854174 Common - uncharacterized relative of glutathione S-transferase MAPEG superfamily-like protein Mext_4778 30 COG3788 COG3788, Uncharacterized relative of glutathione S-transferase, MAPEG superfamily General function prediction only 163851352 Common - domain of unknown function DUF1745 Mext_1925 41 COG3287 COG3287, Uncharacterized conserved protein Function unknown 163851415 Nonpathogen - hypothetical protein Mext_1988 1 None None None 163853675 Common - protein of unknown function DUF1013 Mext_4278 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 163853397 Common - ribosomal protein L11 Mext_3998 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 163853472 Common - helix-turn-helix- domain containing protein AraC type Mext_4074 119 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 163853291 Common - conserved hypothetical protein; putative methyl-accepting chemotaxis protein Mext_3892 137 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163853677 Common - flavoprotein WrbA Mext_4280 122 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 163853951 Nonpathogen - hypothetical protein Mext_4555 5 None None None 163853548 Nonpathogen - hypothetical protein Mext_4151 1 COG0546 Gph, Predicted phosphatases General function prediction only 163849809 Nonpathogen - hypothetical protein Mext_0359 1 None None None 163850138 Common - protein of unknown function DUF1491 Mext_0698 24 COG5447 COG5447, Uncharacterized conserved protein Function unknown 163853958 Common - Nicotinate phosphoribosyltransferase Mext_4562 59 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 163854219 Common - TspO/MBR family protein Mext_4823 61 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 163853233 Common - cytochrome d ubiquinol oxidase, subunit II Mext_3833 152 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 163849677 Common - cytochrome c oxidase, subunit I Mext_0223 162 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 163850075 Common - hypothetical protein Mext_0633 10 None None None 163854194 Common - 2-alkenal reductase Mext_4798 221 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 163851009 Nonpathogen - hypothetical protein Mext_1582 1 None None None 163853227 Common - PAS sensor protein Mext_3826 121 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163851581 Common - ribosomal protein S7 Mext_2158 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 163851604 Common - preprotein translocase, SecY subunit Mext_2181 225 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 163850797 Common - hypothetical protein Mext_1368 5 None None None 163852929 Common - hypothetical protein Mext_3516 16 None None None 163852284 Common - response regulator receiver Mext_2866 24 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 163849506 Nonpathogen - hypothetical protein Mext_0050 1 COG4907 COG4907, Predicted membrane protein Function unknown 163851892 Common - ribonuclease BN Mext_2469 127 COG1295 Rbn, Predicted membrane protein Function unknown 163850853 Nonpathogen - gene transfer agent (GTA) orfg10 Mext_1424 1 None None None 163850185 Common - plasmid pRiA4b ORF-3 family protein Mext_0745 45 None None None 163854132 Common - lytic murein transglycosylase Mext_4736 99 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 163850217 Nonpathogen - hypothetical protein Mext_0780 1 None None None 163849763 Common - hypothetical protein Mext_0311 14 None None None 163851151 Nonpathogen - hypothetical protein Mext_1724 1 None None None 163850027 Common - putative membrane protein of unknown function Mext_0585 21 COG5488 COG5488, Integral membrane protein Function unknown 163854278 Nonpathogen - hypothetical protein Mext_4882 1 None None None 163853865 Common - helix-turn-helix domain protein Mext_4469 111 COG1396 HipB, Predicted transcriptional regulators Transcription 163850724 Common - NAD-dependent aldehyde dehydrogenase-like protein Mext_1295 201 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 163852495 Common - hypothetical protein Mext_3078 4 None None None 163852712 Common - integral membrane protein MviN Mext_3297 189 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 163850732 Common - Urease accessory protein UreF Mext_1303 52 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 163853283 Common - UDP-N-acetylglucosamine 2-epimerase Mext_3884 25 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 163850081 Common - flagellar motor switch protein FliN Mext_0639 122 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 163851000 Common - RelE-like cytotoxic translational repressor of toxin-antitoxin stability system Mext_1573 30 COG4737 COG4737, Uncharacterized protein conserved in bacteria Function unknown 163852513 Common - protein of unknown function DUF839 Mext_3097 74 COG3211 PhoX, Predicted phosphatase General function prediction only 163850093 Common - signal recognition particle protein Mext_0651 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 163849536 Common - hypothetical protein Mext_0080 18 None None None 163851099 Common - PAS sensor protein Mext_1672 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163850483 Common - ChaC family protein Mext_1050 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 163851543 Common - cyclic nucleotide-binding Mext_2120 31 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163851642 Nonpathogen - hypothetical protein Mext_2219 1 None None None 163852604 Common - metal-dependent phosphohydrolase HD sub domain Mext_3189 43 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 163851066 Common - Phosphoenolpyruvate carboxykinase (ATP) Mext_1639 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 163850705 Common - hypothetical protein Mext_1276 12 None None None 163849897 Common - hypothetical protein Mext_0448 3 None None None 163850895 Common - ATP synthase F1, beta subunit Mext_1466 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 163853688 Common - MOSC domain containing protein Mext_4291 78 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 163852658 Nonpathogen - hypothetical protein Mext_3243 1 None None None 163853349 Nonpathogen - hypothetical protein Mext_3950 1 None None None 163852827 Common - conserved hypothetical proteinn Mext_3413 16 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 163852954 Nonpathogen - hypothetical protein Mext_3543 1 None None None 163853142 Common - L-serine dehydratase 1 Mext_3740 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 163851995 Nonpathogen - hypothetical protein Mext_2573 1 None None None 163851929 Common - phosphoglycerate mutase 1 family Mext_2506 180 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 163851595 Common - AAA ATPase central domain protein Mext_2172 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 163851626 Common - monooxygenase FAD-binding Mext_2203 65 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 163852809 Common - thioesterase superfamily protein Mext_3395 67 COG0824 FcbC, Predicted thioesterase General function prediction only 163851293 Nonpathogen - hypothetical protein Mext_1866 1 None None None 163852763 Common - cyclic nucleotide-binding Mext_3348 145 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163850846 Common - hypothetical protein Mext_1417 21 None None None 163852704 Common - argininosuccinate lyase Mext_3289 228 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 163851109 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_1682 75 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163850241 Nonpathogen - hypothetical protein Mext_0808 1 None None None 163849541 Common - hypothetical protein Mext_0085 10 COG4469 CoiA, Competence protein General function prediction only 163853335 Common - DNA repair protein RadA Mext_3936 218 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 163850726 Nonpathogen - hypothetical protein Mext_1297 1 None None None 163854183 Common - FAD linked oxidase domain protein Mext_4787 149 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 163849735 Nonpathogen - hypothetical protein Mext_0283 2 None None None 163850557 Nonpathogen - hypothetical protein Mext_1125 4 None None None 163850577 Common - nitrate ABC transporter, inner membrane subunit Mext_1147 195 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163851515 Common - Transketolase domain protein Mext_2091 220 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 163853077 Nonpathogen - hypothetical protein Mext_3671 1 None None None 163853213 Common - hypothetical protein Mext_3811 8 None None None 163851974 Common - imidazoleglycerol phosphate synthase, cyclase subunit Mext_2552 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 163851821 Common - SecA DEAD domain protein Mext_2398 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 163849700 Nonpathogen - hypothetical protein Mext_0247 11 COG4641 COG4641, Uncharacterized protein conserved in bacteria Function unknown 163853340 Common - ribosomal protein S18 Mext_3941 214 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 163853537 Common - MxaD protein, putative Mext_4140 20 None None None 163850659 Nonpathogen - hypothetical protein Mext_1229 3 None None None 163851205 Common - cobalamin synthesis protein P47K Mext_1778 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 163850192 Common - ATP-binding region ATPase domain protein Mext_0752 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163850929 Common - regulatory protein TetR Mext_1500 10 None None None 163851262 Common - histidine biosynthesis protein Mext_1835 149 COG1411 COG1411, Uncharacterized protein related to proFAR isomerase (HisA) General function prediction only 163851079 Common - sarcosine oxidase, alpha subunit family Mext_1652 174 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 163852407 Common - Chorismate synthase Mext_2990 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 163852547 Common - 6-phosphogluconate dehydrogenase NAD-binding Mext_3131 147 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 163853354 Common - Citrate transporter Mext_3955 38 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 163851928 Common - magnesium chelatase ATPase subunit I Mext_2505 76 COG1239 ChlI, Mg-chelatase subunit ChlI Coenzyme metabolism 163853217 Common - conserved hypothetical membrane spanning protein Mext_3815 21 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 163849658 Common - glycosyl transferase group 1 Mext_0204 65 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163850728 Common - ammonium transporter Mext_1299 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 163852684 Common - ATP-binding region ATPase domain protein Mext_3269 19 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 163853949 Nonpathogen - hypothetical protein Mext_4553 1 None None None 163851101 Common - LysR substrate-binding Mext_1674 131 COG0583 LysR, Transcriptional regulator Transcription 163850504 Common - proton-translocating NADH-quinone oxidoreductase, chain N Mext_1072 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 163853748 Nonpathogen - hypothetical protein Mext_4351 1 None None None 163853462 Common - magnesium-protoporphyrin IX monomethyl ester anaerobic oxidative cyclase Mext_4064 88 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 163850923 Common - uroporphyrinogen decarboxylase Mext_1494 174 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 163850273 Common - peptidase M15D vanX D-ala-D-ala dipeptidase Mext_0840 51 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 163850207 Common - transposase IS4 family protein Mext_0767 57 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 163852189 Common - PAS sensor protein Mext_2770 188 COG3604 FhlA, Transcriptional regulator containing GAF, AAA-type ATPase, and DNA binding domains Transcription / Signal transduction mechanisms 163853493 Nonpathogen - flagellar hook-length control protein Mext_4095 6 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 163849503 Nonpathogen - hypothetical protein Mext_0047 2 None None None 163849576 Common - hypothetical protein Mext_0120 51 None None None 163853640 Nonpathogen - hypothetical protein Mext_4243 14 COG3636 COG3636, Predicted transcriptional regulator Transcription 163850204 Nonpathogen - hypothetical protein Mext_0764 2 None None None 163852937 Common - LysR substrate-binding Mext_3526 156 COG0583 LysR, Transcriptional regulator Transcription 163852661 Common - Sel1 domain protein repeat-containing protein Mext_3246 104 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 163853899 Common - SNARE associated Golgi protein Mext_4503 163 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 163852918 Common - regulatory protein Crp Mext_3505 119 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163851303 Nonpathogen - hypothetical protein Mext_1876 3 None None None 163851383 Common - exodeoxyribonuclease III Xth Mext_1956 196 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 163849862 Common - Extensin family protein Mext_0412 36 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 163852612 Common - DNA-directed RNA polymerase, omega subunit Mext_3197 38 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 163849537 Common - integrase family protein Mext_0081 147 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163851072 Common - succinyl-CoA synthetase, alpha subunit Mext_1645 210 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 163851966 Common - cytochrome c1 Mext_2544 49 COG2857 CYT1, Cytochrome c1 Energy production and conversion 163851944 Common - RND efflux system, outer membrane lipoprotein, NodT family Mext_2522 112 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 163851986 Common - SSS sodium solute transporter superfamily Mext_2564 171 COG4147 DhlC, Predicted symporter General function prediction only 163852325 Common - aminotransferase class-III Mext_2908 235 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 163851799 Common - Glutamate--ammonia ligase Mext_2376 81 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 163849740 Common - crotonyl-CoA reductase Mext_0288 155 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 163853850 Common - TENA/THI-4 domain protein Mext_4454 73 COG0819 TenA, Putative transcription activator Transcription 163851092 Common - type I secretion membrane fusion protein, HlyD family Mext_1665 115 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163851364 Common - DNA/RNA non-specific endonuclease Mext_1937 40 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 163850600 Common - acyl-CoA dehydrogenase domain protein Mext_1170 138 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 163851588 Common - ribosomal protein L2 Mext_2165 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 163850952 Common - NUDIX hydrolase Mext_1525 39 COG4923 COG4923, Uncharacterized conserved protein Function unknown 163850646 Nonpathogen - hypothetical protein Mext_1216 1 None None None 163851455 Nonpathogen - hypothetical protein Mext_2031 1 None None None 163853155 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Mext_3753 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 163852721 Common - Methionine adenosyltransferase Mext_3306 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 163852602 Common - hypothetical protein Mext_3187 7 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 163851875 Common - helix-turn-helix HxlR type Mext_2452 136 COG1733 COG1733, Predicted transcriptional regulators Transcription 163849662 Common - ThiJ/PfpI domain protein Mext_0208 151 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 163851846 Common - glycosyltransferase Mext_2423 63 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163852772 Common - hypothetical protein Mext_3358 19 COG0782 GreA, Transcription elongation factor Transcription 163852167 Common - N-formylglutamate amidohydrolase Mext_2748 41 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 163853924 Common - aldehyde oxidase and xanthine dehydrogenase molybdopterin binding Mext_4528 104 COG1529 CoxL, Aerobic-type carbon monoxide dehydrogenase, large subunit CoxL/CutL homologs Energy production and conversion 163850077 Common - transcriptional regulator domain protein Mext_0635 198 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163849907 Common - RNA polymerase sigma factor, sigma-70 family Mext_0458 160 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 163851291 Common - integrase family protein Mext_1864 152 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163849767 Nonpathogen - sensor histidine kinase with PAS/PAC and response regulator receiver domains Mext_0315 1 None None None 163853940 Common - short-chain dehydrogenase/reductase SDR Mext_4544 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163852620 Common - PhoH family protein Mext_3205 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 163851529 Common - Dihydroorotate oxidase Mext_2106 214 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 163851621 Nonpathogen - hypothetical protein Mext_2198 2 None None None 163851539 Common - response regulator receiver Mext_2116 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163853067 Common - N-acetylmuramoyl-L-alanine amidase Mext_3661 177 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 163850811 Common - TonB-dependent receptor Mext_1382 104 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 163849685 Common - cytochrome B561 Mext_0231 32 COG3038 CybB, Cytochrome B561 Energy production and conversion 163851400 Common - glycosyl transferase group 1 Mext_1973 68 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163850922 Common - protein of unknown function DUF299 Mext_1493 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 163851881 Nonpathogen - hypothetical protein Mext_2458 1 None None None 163852124 Common - GCN5-related N-acetyltransferase Mext_2705 110 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 163851576 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_2153 41 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 163849837 Common - cytoplasmic chaperone TorD family protein Mext_0387 31 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 163852155 Nonpathogen - photosynthetic reaction center L subunit Mext_2736 18 None None None 163849856 Common - protein of unknown function UPF0102 Mext_0406 21 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 163852741 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Mext_3326 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163852651 Common - putative mRNA 3-end processing factor Mext_3236 70 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 163853874 Nonpathogen - hypothetical protein Mext_4478 1 None None None 163852320 Nonpathogen - protein of unknown function DUF1328 Mext_2903 1 COG5487 COG5487, Small integral membrane protein Function unknown 163849732 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Mext_0280 196 COG0546 Gph, Predicted phosphatases General function prediction only 163849813 Common - PAS sensor protein Mext_0363 122 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163852414 Common - AIG2 family protein Mext_2997 14 COG2105 COG2105, Uncharacterized conserved protein Function unknown 163851277 Common - ABC transporter related Mext_1850 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 163850818 Nonpathogen - hypothetical protein Mext_1389 1 None None None 163852275 Nonpathogen - hypothetical protein Mext_2857 1 None None None 163853305 Common - glutamine amidotransferase of anthranilate synthase Mext_3906 240 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 163850969 Common - Electron transfer flavoprotein alpha/beta-subunit Mext_1542 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 163850155 Common - Chromosome segregation ATPase-like protein Mext_0715 168 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 163853981 Common - polysaccharide deacetylase Mext_4585 56 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 163850831 Nonpathogen - hypothetical protein Mext_1402 1 None None None 163851186 Common - methionine biosynthesis protein MetW Mext_1759 60 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 163852793 Common - urea ABC transporter, permease protein UrtC Mext_3379 120 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 163850312 Common - HI0933 family protein Mext_0879 128 COG2081 COG2081, Predicted flavoproteins General function prediction only 163854169 Common - ROSMUCR transcriptional regulator Mext_4773 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 163854117 Common - DNA-directed DNA polymerase Mext_4721 186 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 163853823 Common - hypothetical protein Mext_4427 5 None None None 163852265 Common - molybdopterin-guanine dinucleotide biosynthesis protein B Mext_2847 94 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 163853163 Common - IucA/IucC family protein Mext_3761 200 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 163852226 Common - Rieske (2Fe-2S) domain protein Mext_2807 72 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 163852692 Common - glutaredoxin 3 Mext_3277 136 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 163852670 Nonpathogen - hypothetical protein Mext_3255 8 None None None 163849474 Nonpathogen - hypothetical protein Mext_0017 4 None None None 163852803 Nonpathogen - hypothetical protein Mext_3389 1 None None None 163852911 Common - heat shock protein Hsp20 Mext_3498 159 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 163852311 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_2893 84 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163851524 Common - cell divisionFtsK/SpoIIIE Mext_2101 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 163851409 Common - low molecular weight phosphotyrosine protein phosphatase Mext_1982 82 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 163851659 Common - flavodoxin/nitric oxide synthase Mext_2236 102 COG0369 CysJ, Sulfite reductase, alpha subunit (flavoprotein) Inorganic ion transport and metabolism 163854261 Common - hypothetical protein Mext_4865 12 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 163854164 Common - Holliday junction DNA helicase RuvB Mext_4768 233 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 163851627 Common - hypothetical protein Mext_2204 14 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 163850472 Common - precorrin-4 C11-methyltransferase Mext_1039 199 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 163850357 Common - cytochrome c class I Mext_0924 55 COG3474 COG3474, Cytochrome c2 Energy production and conversion 163853455 Common - LysR substrate-binding Mext_4057 98 COG0583 LysR, Transcriptional regulator Transcription 163853616 Common - protein of unknown function DUF6 transmembrane Mext_4219 38 None None None 163851701 Common - hypothetical protein Mext_2278 7 None None None 163850101 Common - phosphoserine aminotransferase Mext_0659 65 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 163849645 Common - chemotaxis sensory transducer Mext_0191 129 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163851275 Common - hypothetical protein Mext_1848 9 None None None 163851532 Nonpathogen - hypothetical protein Mext_2109 4 None None None 163851031 Common - polysaccharide deacetylase Mext_1604 58 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 163853040 Common - Glutathione S-transferase domain Mext_3634 73 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163852018 Common - alanyl-tRNA synthetase Mext_2598 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163849792 Common - 3-deoxy-D-manno-octulosonate cytidylyltransferase Mext_0340 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 163849921 Nonpathogen - hypothetical protein Mext_0472 1 None None None 163851145 Common - Rieske (2Fe-2S) domain protein Mext_1718 76 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 163852571 Common - putative ICC-like phosphoesterase Mext_3155 53 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 163853021 Nonpathogen - hypothetical protein Mext_3615 1 None None None 163850043 Common - Inositol-phosphate phosphatase Mext_0601 212 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 163854029 Nonpathogen - hypothetical protein Mext_4633 1 None None None 163852900 Common - twin-arginine translocation pathway signal Mext_3487 91 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163853450 Common - glutathione S-transferase-like protein Mext_4052 17 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163849996 Nonpathogen - hypothetical protein Mext_0553 2 None None None 163852369 Nonpathogen - hypothetical protein Mext_2952 1 None None None 163852389 Common - metallophosphoesterase Mext_2972 33 COG1409 Icc, Predicted phosphohydrolases General function prediction only 163849556 Nonpathogen - hypothetical protein Mext_0100 1 None None None 163850805 Common - RNA polymerase sigma factor, sigma-70 family Mext_1376 134 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 163850943 Common - addiction module antidote protein, CC2985 family Mext_1516 29 COG3609 COG3609, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain Transcription 163852083 Common - cytochrome P450 Mext_2663 81 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 163852061 Common - Ethyl tert-butyl ether degradation EthD Mext_2641 10 None None None 163853736 Common - acriflavin resistance protein Mext_4339 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163850544 Nonpathogen - hypothetical protein Mext_1112 3 None None None 163849912 Common - Mandelate racemase/muconate lactonizing protein Mext_0463 89 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 163853514 Common - nuclease (SNase domain protein) Mext_4116 15 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 163852586 Common - Glycine hydroxymethyltransferase Mext_3171 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 163850235 Common - PAS sensor protein Mext_0802 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163850565 Common - Cellulose synthase (UDP-forming) Mext_1133 140 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163850580 Common - acyl-CoA dehydrogenase-like protein Mext_1150 31 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 163851979 Common - response regulator receiver Mext_2557 57 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163854231 Common - porin Mext_4835 12 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 163849711 Nonpathogen - hypothetical protein Mext_0259 1 None None None 163853934 Common - oxidoreductase domain protein Mext_4538 170 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 163851760 Nonpathogen - hypothetical protein Mext_2337 3 None None None 163852792 Common - urea ABC transporter, ATP-binding protein UrtD Mext_3378 249 COG4674 COG4674, Uncharacterized ABC-type transport system, ATPase component General function prediction only 163849724 Common - putative type II DNA modification enzyme Mext_0272 50 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 163850447 Common - short-chain dehydrogenase/reductase SDR Mext_1014 232 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 163849957 Common - hypothetical protein Mext_0514 25 None None None 163849930 Common - protein of unknown function DUF1228 Mext_0485 55 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163850668 Common - response regulator receiver Mext_1238 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163853388 Nonpathogen - hypothetical protein Mext_3989 1 None None None 163851338 Common - arsenical pump membrane protein Mext_1911 108 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 163852698 Common - hypothetical protein Mext_3283 29 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 163852875 Common - polysaccharide export protein Mext_3462 62 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 163850123 Common - protein of unknown function DUF1078 domain protein Mext_0683 127 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 163850424 Common - Ribulose-phosphate 3-epimerase Mext_0991 215 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 163849995 Nonpathogen - hypothetical protein Mext_0552 1 None None None 163852442 Nonpathogen - hypothetical protein Mext_3025 1 None None None 163853814 Common - major facilitator superfamily MFS_1 Mext_4418 67 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163853603 Common - Aldehyde Dehydrogenase_ Mext_4206 222 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 163850996 Common - hypothetical protein Mext_1569 4 None None None 163850463 Common - Gamma-glutamyltransferase Mext_1030 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 163851606 Common - ribosomal protein L30 Mext_2183 89 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 163850683 Common - protein of unknown function DUF442 Mext_1253 26 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 163850512 Common - NADH-quinone oxidoreductase, F subunit Mext_1080 164 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 163853803 Common - hypothetical protein Mext_4407 16 None None None 163852668 Common - processing peptidase Mext_3253 167 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 163852024 Common - flagellar biosynthetic protein FliR Mext_2604 124 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 163852134 Common - protein of unknown function UPF0060 Mext_2715 76 COG1742 COG1742, Uncharacterized conserved protein Function unknown 163852162 Common - alpha/beta hydrolase fold Mext_2743 133 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163853383 Common - DEAD/DEAH box helicase domain protein Mext_3984 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 163852245 Common - Carbonate dehydratase Mext_2827 152 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 163850085 Common - chemotaxis MotA protein Mext_0643 92 COG1291 MotA, Flagellar motor component Cell motility and secretion 163851740 Common - nitroreductase Mext_2317 82 COG0778 NfnB, Nitroreductase Energy production and conversion 163852171 Common - Peptidoglycan-binding domain 1 protein Mext_2752 76 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 163852178 Common - NAD(P)(+) transhydrogenase (AB-specific) Mext_2759 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 163853577 Common - protein of unknown function UPF0061 Mext_4180 110 COG0397 COG0397, Uncharacterized conserved protein Function unknown 163854001 Common - Homoserine O-succinyltransferase Mext_4605 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 163850917 Common - dephospho-CoA kinase Mext_1488 206 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 163850003 Common - aminodeoxychorismate lyase Mext_0560 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 163850537 Common - PRC-barrel domain protein Mext_1105 29 None None None 163852363 Common - D-alanine--D-alanine ligase Mext_2946 212 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 163852930 Common - DNA-directed DNA polymerase Mext_3517 180 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 163853360 Common - extracellular solute-binding protein family 3 Mext_3961 100 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 163853791 Nonpathogen - hypothetical protein Mext_4395 1 None None None 163852057 Common - aconitate hydratase 1 Mext_2637 223 COG1048 AcnA, Aconitase A Energy production and conversion 163852297 Nonpathogen - hypothetical protein Mext_2879 8 COG3143 CheZ, Chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163852377 Common - chaperone protein DnaK Mext_2960 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 163852638 Common - uroporphyrin-III C-methyltransferase Mext_3223 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 163853195 Common - regulatory protein MarR Mext_3793 96 COG1846 MarR, Transcriptional regulators Transcription 163851167 Common - Ureidoglycolate hydrolase Mext_1740 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 163849676 Common - cytochrome c oxidase, subunit II Mext_0222 157 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 163852454 Nonpathogen - hypothetical protein Mext_3037 2 None None None 163853438 Nonpathogen - hypothetical protein Mext_4040 3 None None None 163850186 Common - protein of unknown function DUF262 Mext_0746 32 None None None 163850376 Nonpathogen - hypothetical protein Mext_0943 1 None None None 163850628 Common - urease accessory protein UreG Mext_1198 155 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 163849557 Common - integrase family protein Mext_0101 11 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 163852182 Common - cyclic nucleotide-binding Mext_2763 37 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163852471 Common - Invasion associated locus B family protein Mext_3054 9 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 163850909 Common - beta-lactamase Mext_1480 109 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 163852861 Nonpathogen - hypothetical protein Mext_3447 1 None None None 163852094 Common - dihydroxy-acid dehydratase Mext_2675 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 163852006 Common - response regulator receiver Mext_2585 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 163854256 Nonpathogen - hypothetical protein Mext_4860 1 None None None 163853188 Nonpathogen - hypothetical protein Mext_3786 1 None None None 163849561 Common - SNARE associated Golgi protein Mext_0105 137 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 163852370 Common - hypothetical protein Mext_2953 12 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163853003 Common - Mn2+/Fe2+ transporter, NRAMP family Mext_3597 101 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 163853714 Common - amidohydrolase Mext_4317 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 163850363 Nonpathogen - GCN5-related N-acetyltransferase Mext_0930 4 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 163849569 Common - PAS sensor protein Mext_0113 91 None None None 163849491 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mext_0035 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 163849619 Common - Lytic transglycosylase catalytic Mext_0165 51 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 163849757 Common - SMC domain protein Mext_0305 80 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 163852333 Nonpathogen - hypothetical protein Mext_2916 1 None None None 163853857 Common - glutamine amidotransferase class-II Mext_4461 77 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 163853120 Nonpathogen - hypothetical protein Mext_3718 2 None None None 163849697 Common - NAD-dependent epimerase/dehydratase Mext_0244 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163849788 Common - Ribulose-phosphate 3-epimerase Mext_0336 219 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 163850714 Common - ABC transporter related Mext_1285 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 163853447 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Mext_4049 187 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 163851855 Common - Resolvase domain Mext_2432 128 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 163850605 Nonpathogen - hypothetical protein Mext_1175 1 None None None 163853862 Common - ferredoxin Mext_4466 59 COG0633 Fdx, Ferredoxin Energy production and conversion 163853904 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Mext_4508 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163853554 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Mext_4157 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 163853280 Common - transcription factor CarD Mext_3880 83 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 163854020 Common - Aspartate racemase Mext_4624 76 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 163854238 Common - tol-pal system protein YbgF Mext_4842 90 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 163850621 Common - membrane protein of uknown function UCP014873 Mext_1191 24 COG4803 COG4803, Predicted membrane protein Function unknown 163852194 Common - Catalase Mext_2775 46 COG3546 COG3546, Mn-containing catalase Inorganic ion transport and metabolism 163852467 Common - flagellar motor switch protein FliM Mext_3050 106 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 163849550 Common - putative cytochrome c oxidase subunit III protein Mext_0094 36 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 163851392 Common - response regulator receiver Mext_1965 30 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 163853279 Common - 4Fe-4S ferredoxin iron-sulfur binding domain protein Mext_3879 155 COG1146 COG1146, Ferredoxin Energy production and conversion 163850877 Common - cob(I)alamin adenosyltransferase Mext_1448 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 163852888 Common - fumarylacetoacetate (FAA) hydrolase Mext_3475 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 163852145 Common - phytoene desaturase Mext_2726 65 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 163849602 Common - hypothetical protein Mext_0147 7 None None None 163850499 Common - prolyl-tRNA synthetase Mext_1066 247 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163851228 Common - Phosphoenolpyruvate carboxylase Mext_1801 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 163849521 Common - nuclease (SNase domain protein) Mext_0065 74 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 163851984 Common - acetate--CoA ligase Mext_2562 214 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 163851917 Common - conserved hypothetical membrane spanning protein Mext_2494 21 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 163854074 Common - lipid-A-disaccharide synthase Mext_4678 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 163852940 Nonpathogen - hypothetical protein Mext_3529 1 None None None 163852121 Common - aspartate-semialdehyde dehydrogenase Mext_2702 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 163849706 Nonpathogen - hypothetical protein Mext_0254 1 None None None 163852847 Common - Ppx/GppA phosphatase Mext_3433 181 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 163849674 Common - hypothetical protein Mext_0220 17 None None None 163850371 Nonpathogen - hypothetical protein Mext_0938 1 None None None 163854245 Common - gamma-glutamyltransferase Mext_4849 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 163850865 Common - precorrin-2 C20-methyltransferase Mext_1436 166 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 163852891 Common - Resolvase domain Mext_3478 12 None None None 163851023 Common - K potassium transporter Mext_1596 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 163851217 Common - hypothetical protein Mext_1790 11 None None None 163854247 Common - ABC transporter related Mext_4851 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 163850826 Common - small multidrug resistance protein Mext_1397 139 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 163853179 Common - ribosomal protein S21 Mext_3777 39 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 163850263 Common - hypothetical protein Mext_0830 18 None None None 163849947 Common - Myo-inositol-1-phosphate synthase Mext_0503 57 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 163850422 Common - OpgC protein Mext_0989 23 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 163854154 Nonpathogen - hypothetical protein Mext_4758 1 None None None 163852773 Common - hypothetical protein Mext_3359 7 None None None 163849938 Nonpathogen - hypothetical protein Mext_0494 1 None None None 163853821 Common - metallophosphoesterase Mext_4425 61 COG1409 Icc, Predicted phosphohydrolases General function prediction only 163850492 Common - hypothetical protein Mext_1059 38 COG4338 COG4338, Uncharacterized protein conserved in bacteria Function unknown 163853064 Common - aminotransferase class I and II Mext_3658 235 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 163849656 Common - hypothetical protein Mext_0202 9 COG4671 COG4671, Predicted glycosyl transferase General function prediction only 163849844 Common - hypothetical protein Mext_0394 4 None None None 163850614 Nonpathogen - protein of unknown function DUF1236 Mext_1184 5 None None None 163849661 Common - ABC transporter related Mext_0207 228 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 163851886 Common - methyltransferase small Mext_2463 70 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 163850007 Common - secretion protein HlyD family protein Mext_0564 141 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163850644 Nonpathogen - hypothetical protein Mext_1214 1 None None None 163850776 Nonpathogen - hypothetical protein Mext_1347 2 None None None 163852113 Common - acyltransferase 3 Mext_2694 36 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 163851147 Common - ABC transporter related Mext_1720 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163851054 Common - ribosomal protein L35 Mext_1627 138 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 163852815 Common - Sec-independent protein translocase, TatC subunit Mext_3401 202 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 163852451 Common - SlyX family protein Mext_3034 19 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 163852567 Common - protein of unknown function DUF224 cysteine-rich region domain protein Mext_3151 178 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 163853686 Common - Phosphoglycerate mutase Mext_4289 36 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 163851271 Common - hypothetical protein Mext_1844 26 COG1891 COG1891, Uncharacterized protein conserved in archaea Function unknown 163854121 Common - L-threonine-O-3-phosphate decarboxylase Mext_4725 93 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 163852961 Common - NAD-dependent epimerase/dehydratase Mext_3553 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163852239 Common - helicase domain protein Mext_2821 113 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 163853133 Common - glycine betaine/L-proline ABC transporter, ATPase subunit Mext_3731 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 163850677 Common - conserved hypothetical protein; putative flagellin C-ter domain Mext_1247 61 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 163853320 Common - efflux transporter, RND family, MFP subunit Mext_3921 75 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163853523 Common - Hemolysin-type calcium-binding region Mext_4126 84 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 163851602 Common - ribosomal protein S13 Mext_2179 238 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 163851086 Common - glutamine synthetase, type III Mext_1659 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 163850884 Common - PAS sensor protein Mext_1455 211 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163851797 Common - nitrogen regulatory protein P-II Mext_2374 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 163852927 Common - Alcohol dehydrogenase zinc-binding domain protein Mext_3514 210 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 163850704 Common - transposase IS4 family protein Mext_1275 14 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 163852230 Common - ABC transporter related Mext_2811 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 163852896 Nonpathogen - hypothetical protein Mext_3483 1 None None None 163852240 Common - PAS sensor protein Mext_2822 214 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 163851905 Common - putative pilus assembly protein CpaE Mext_2482 130 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 163850485 Common - DNA topoisomerase IV, A subunit Mext_1052 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 163853150 Common - Rieske (2Fe-2S) domain protein Mext_3748 83 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 163850047 Common - glycine oxidase ThiO Mext_0605 174 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 163852781 Common - inner-membrane translocator Mext_3367 149 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 163850663 Common - glycosyl transferase group 1 Mext_1233 105 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163850799 Common - hypothetical protein Mext_1370 5 None None None 163850317 Nonpathogen - hypothetical protein Mext_0884 10 None None None 163851196 Nonpathogen - hypothetical protein Mext_1769 1 None None None 163851122 Common - isochorismatase hydrolase Mext_1695 128 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 163854258 Common - protein of unknown function DUF892 Mext_4862 36 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 163851127 Common - inner-membrane translocator Mext_1700 106 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 163849923 Nonpathogen - hypothetical protein Mext_0474 1 None None None 163854018 Common - glycosyl transferase group 1 Mext_4622 140 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163850287 Common - glycine cleavage system H protein Mext_0854 185 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 163852689 Common - UTP-glucose-1-phosphate uridylyltransferase Mext_3274 223 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 163850635 Common - OsmC family protein Mext_1205 5 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 163852278 Common - response regulator receiver Mext_2860 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163851826 Common - hypothetical protein Mext_2403 4 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 163851684 Nonpathogen - hypothetical protein Mext_2261 3 None None None 163852559 Common - Formaldehyde-activating enzyme (Fae) Mext_3143 24 COG1795 COG1795, Uncharacterized conserved protein Function unknown 163853592 Common - cyclic nucleotide-binding Mext_4195 126 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163853769 Common - ABC transporter related Mext_4372 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 163851994 Common - protein of unknown function DUF1508 Mext_2572 11 COG3422 COG3422, Uncharacterized conserved protein Function unknown 163849755 Nonpathogen - hypothetical protein Mext_0303 1 None None None 163851059 Common - UBA/THIF-type NAD/FAD binding protein Mext_1632 222 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 163852858 Common - MaoC domain protein dehydratase Mext_3444 99 COG2030 MaoC, Acyl dehydratase Lipid metabolism 163852538 Common - ABC transporter related Mext_3122 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 163850693 Common - septum site-determining protein MinC Mext_1263 102 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 163852799 Common - precorrin-6A synthase (deacetylating) Mext_3385 55 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 163852317 Common - hypothetical protein Mext_2900 25 COG4446 COG4446, Uncharacterized protein conserved in bacteria Function unknown 163851989 Common - Heparinase II/III family protein Mext_2567 41 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 163853660 Common - heat shock protein Hsp20 Mext_4263 66 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 163850596 Common - hypothetical protein Mext_1166 25 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163850835 Common - cytochrome c assembly protein Mext_1406 154 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 163851938 Common - binding-protein-dependent transport systems inner membrane component Mext_2515 219 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 163850083 Nonpathogen - hypothetical protein Mext_0641 2 None None None 163853990 Nonpathogen - putative acyl carrier protein Mext_4594 3 None None None 163853902 Common - hypothetical protein Mext_4506 12 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 163849668 Common - FAD linked oxidase domain protein Mext_0214 193 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 163850738 Common - urease, gamma subunit Mext_1309 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 163849854 Common - extracellular ligand-binding receptor Mext_0404 30 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 163854073 Common - protein of unknown function DUF1009 Mext_4677 44 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 163851489 Common - protein of unknown function UPF0118 Mext_2065 135 COG0628 PerM, Predicted permease General function prediction only 163851497 Common - ribosomal protein S2 Mext_2073 228 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 163851785 Common - metallophosphoesterase Mext_2362 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 163850910 Nonpathogen - 4'-phosphopantetheinyl transferase Mext_1481 11 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 163850328 Common - inositol monophosphatase Mext_0895 198 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 163849829 Common - ABC-2 type transporter Mext_0379 158 COG1511 COG1511, Predicted membrane protein Function unknown 163851469 Common - Orn/DAP/Arg decarboxylase 2 Mext_2045 210 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 163852481 Common - glutamyl-tRNA(Gln) amidotransferase, B subunit Mext_3064 211 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 163852523 Common - hypothetical protein Mext_3107 21 None None None 163854186 Nonpathogen - hypothetical protein Mext_4790 1 None None None 163851512 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family Mext_2088 118 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 163850870 Common - cobalamin biosynthesis protein CobW Mext_1441 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 163849916 Nonpathogen - hypothetical protein Mext_0467 1 None None None 163852249 Common - acriflavin resistance protein Mext_2831 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 163853411 Common - Radical SAM domain protein Mext_4012 85 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 163850191 Common - Cupin 2 conserved barrel domain protein Mext_0751 39 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 163850781 Common - short-chain dehydrogenase/reductase SDR Mext_1352 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163851067 Common - radical SAM enzyme, Cfr family Mext_1640 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 163851062 Common - methionyl-tRNA formyltransferase Mext_1635 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 163851517 Common - TRAP dicarboxylate transporter, DctP subunit Mext_2093 98 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 163851774 Common - 60 kDa inner membrane insertion protein Mext_2351 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 163853013 Common - KpsF/GutQ family protein Mext_3607 163 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 163852542 Common - PRC-barrel domain protein Mext_3126 31 None None None 163850344 Common - nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Mext_0911 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 163851475 Common - ubiquinol-cytochrome c chaperone Mext_2051 22 COG5452 COG5452, Uncharacterized conserved protein Function unknown 163851459 Common - NAD(P)H dehydrogenase (quinone) Mext_2035 97 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 163850278 Common - glycosyl transferase family 2 Mext_0845 101 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163854141 Common - cysteinyl-tRNA synthetase Mext_4745 243 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163853425 Common - Polyribonucleotide nucleotidyltransferase Mext_4027 242 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 163851396 Nonpathogen - hypothetical protein Mext_1969 7 None None None 163850971 Common - 3-hydroxybutyryl-CoA dehydrogenase Mext_1544 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 163853564 Nonpathogen - hypothetical protein Mext_4167 1 None None None 163852998 Nonpathogen - hypothetical protein Mext_3592 1 COG4907 COG4907, Predicted membrane protein Function unknown 163851359 Common - molybdopterin oxidoreductase Mext_1932 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 163851614 Common - ribosomal protein L14 Mext_2191 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 163852626 Common - LysR substrate-binding Mext_3211 188 COG0583 LysR, Transcriptional regulator Transcription 163851933 Common - hydroxyacylglutathione hydrolase Mext_2510 189 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 163853761 Common - Thioredoxin-disulfide reductase Mext_4364 243 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 163851898 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Mext_2475 166 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 163849969 Common - sulfatase Mext_0526 81 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 163852634 Common - hypothetical protein Mext_3219 65 COG4301 COG4301, Uncharacterized conserved protein Function unknown 163852973 Common - glycosyl transferase group 1 Mext_3565 217 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163853218 Nonpathogen - hypothetical protein Mext_3816 1 None None None 163852991 Common - Endonuclease/exonuclease/phosphatase Mext_3585 25 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 163850177 Common - hypothetical protein Mext_0737 4 None None None 163853722 Common - N-acetylglucosamine-6-phosphate deacetylase Mext_4325 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 163852159 Common - type I secretion membrane fusion protein, HlyD family Mext_2740 124 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 163853718 Common - type IV pilus assembly PilZ Mext_4321 8 None None None 163849909 Nonpathogen - Ion transport 2 domain protein Mext_0460 5 None None None 163850350 Common - Extensin family protein Mext_0917 37 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 163849465 Nonpathogen - hypothetical protein Mext_0008 1 None None None 163853699 Nonpathogen - hypothetical protein Mext_4302 2 None None None 163853833 Nonpathogen - Endonuclease/exonuclease/phosphatase Mext_4437 4 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 163849514 Common - peptidase M42 family protein Mext_0058 87 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 163850784 Common - UspA domain protein Mext_1355 58 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 163851541 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_2118 9 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 163852166 Common - Hydroxypyruvate reductase Mext_2747 85 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 163850994 Common - diacylglycerol kinase catalytic region Mext_1567 121 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 163852717 Common - rhamnosyltransferase Mext_3302 13 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 163853568 Common - AMP-dependent synthetase and ligase Mext_4171 206 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163854158 Common - Biopolymer transport protein ExbD/TolR Mext_4762 132 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 163849539 Common - Lytic transglycosylase catalytic Mext_0083 51 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 163852091 Common - NUDIX hydrolase Mext_2672 12 None None None 163853953 Common - alpha/beta hydrolase fold Mext_4557 64 COG2267 PldB, Lysophospholipase Lipid metabolism 163850035 Common - protein of unknown function DUF45 Mext_0593 153 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 163852096 Common - Mandelate racemase/muconate lactonizing protein Mext_2677 117 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 163853224 Common - LysR substrate-binding Mext_3823 178 COG0583 LysR, Transcriptional regulator Transcription 163852552 Common - radical SAM domain protein Mext_3136 17 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 163849614 Nonpathogen - hypothetical protein Mext_0160 3 None None None 163850942 Common - glucose-6-phosphate 1-dehydrogenase Mext_1515 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 163849872 Common - protein of unknown function DUF1058 Mext_0422 44 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 163853974 Common - Patatin Mext_4578 49 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 163852756 Common - aliphatic sulfonates family ABC transporter, periplsmic ligand-binding protein Mext_3341 77 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 163849592 Nonpathogen - hypothetical protein Mext_0137 8 None None None 163851350 Common - magnesium chelatase ChlI subunit Mext_1923 189 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 163852506 Nonpathogen - hypothetical protein Mext_3090 1 None None None 163849749 Common - peptidase C15 pyroglutamyl peptidase I Mext_0297 19 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 163850858 Nonpathogen - peptidase S1 and S6 chymotrypsin/Hap Mext_1429 6 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 163851040 Nonpathogen - hypothetical protein Mext_1613 1 None None None 163852462 Common - flagellar L-ring protein Mext_3045 98 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 163850219 Nonpathogen - hypothetical protein Mext_0782 2 None None None 163850765 Common - hypothetical protein Mext_1336 19 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 163849604 Common - outer membrane adhesin like proteiin Mext_0150 64 None None None 163853928 Nonpathogen - hypothetical protein Mext_4532 1 None None None 163854135 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Mext_4739 145 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 163852472 Common - lytic murein transglycosylase Mext_3055 103 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 163851417 Nonpathogen - hypothetical protein Mext_1990 1 None None None 163849459 Common - DNA polymerase III, beta subunit Mext_0002 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 163850950 Nonpathogen - hypothetical protein Mext_1523 1 None None None 163853243 Common - transport system permease protein Mext_3843 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 163854068 Common - Indole-3-glycerol-phosphate synthase Mext_4672 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 163853642 Common - protein of unknown function zinc metallopeptidase putative Mext_4245 87 COG2321 COG2321, Predicted metalloprotease General function prediction only 163850851 Common - gene transfer agent (GTA) orfg11 Mext_1422 20 COG5281 COG5281, Phage-related minor tail protein Function unknown 163851015 Common - hypothetical protein Mext_1588 17 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 163853501 Common - regulatory protein TetR Mext_4103 145 COG1309 AcrR, Transcriptional regulator Transcription 163850298 Common - von Willebrand factor type A Mext_0865 79 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 163853914 Common - LysR substrate-binding Mext_4518 98 COG0583 LysR, Transcriptional regulator Transcription 163851460 Common - helix-turn-helix HxlR type Mext_2036 146 COG1733 COG1733, Predicted transcriptional regulators Transcription 163854134 Common - 2-nitropropane dioxygenase NPD Mext_4738 82 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 163853474 Common - ornithine carbamoyltransferase Mext_4076 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 163852204 Common - Septum formation initiator Mext_2785 24 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 163852496 Nonpathogen - hypothetical protein Mext_3079 1 None None None 163854210 Common - magnesium chelatase, H subunit Mext_4814 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 163849794 Common - extracellular solute-binding protein family 5 Mext_0342 161 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 163853863 Nonpathogen - Hpt domain protein Mext_4467 7 None None None 163850220 Common - cyclic nucleotide-binding Mext_0783 97 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 163851405 Common - diguanylate cyclase Mext_1978 190 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163852647 Common - BolA family protein Mext_3232 102 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 163850222 Nonpathogen - hypothetical protein Mext_0785 1 None None None 163850606 Common - serine O-acetyltransferase Mext_1176 188 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 163851480 Common - regulatory protein MerR Mext_2056 92 COG0789 SoxR, Predicted transcriptional regulators Transcription 163851246 Common - coenzyme PQQ biosynthesis protein B Mext_1819 51 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 163853098 Common - Lipopolysaccharide biosynthesis protein-like protein Mext_3694 39 COG3754 RgpF, Lipopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 163850856 Common - phage head-tail adaptor Mext_1427 7 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 163852549 Nonpathogen - hypothetical protein Mext_3133 1 None None None 163853281 Common - RNA polymerase sigma factor, sigma-70 family Mext_3881 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 163852749 Common - chaperonin GroEL Mext_3334 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 163851310 Common - hypothetical protein Mext_1883 18 None None None 163853654 Nonpathogen - hypothetical protein Mext_4257 4 None None None 163852710 Nonpathogen - hypothetical protein Mext_3295 1 None None None 163850029 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Mext_0587 164 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 163853238 Common - Peroxiredoxin Mext_3838 209 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 163851746 Common - ROK family protein Mext_2323 165 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 163851158 Common - binding-protein-dependent transport systems inner membrane component Mext_1731 143 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163853516 Common - putative iron uptake protein Mext_4118 2 None None None 163853047 Common - glycosyl transferase family 2 Mext_3641 151 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 163853636 Nonpathogen - hypothetical protein Mext_4239 1 None None None 163854082 Common - protein of unknown function DUF849 Mext_4686 60 COG3246 COG3246, Uncharacterized conserved protein Function unknown 163851429 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_2002 94 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163854050 Nonpathogen - hypothetical protein Mext_4654 1 None None None 163849485 Common - triphosphoribosyl-dephospho-CoA synthase MdcB Mext_0029 41 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 163850319 Common - Cold-shock protein DNA-binding Mext_0886 179 COG1278 CspC, Cold shock proteins Transcription 163850978 Nonpathogen - hypothetical protein Mext_1551 5 None None None 163851231 Common - Carboxymethylenebutenolidase Mext_1804 116 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 163851373 Common - 8-amino-7-oxononanoate synthase Mext_1946 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 163852277 Common - TspO/MBR family protein Mext_2859 62 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 163851177 Nonpathogen - hypothetical protein Mext_1750 1 None None None 163849481 Common - malonate decarboxylase acyl carrier protein Mext_0025 20 None None None 163852072 Common - GSCFA domain protein Mext_2652 13 None None None 163854271 Common - PAS sensor protein Mext_4875 220 COG3300 COG3300, MHYT domain (predicted integral membrane sensor domain) Signal transduction mechanisms 163850025 Common - sulfate ABC transporter, inner membrane subunit CysW Mext_0583 188 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 163850553 Nonpathogen - hypothetical protein Mext_1121 1 None None None 163854199 Nonpathogen - hypothetical protein Mext_4803 1 None None None 163852212 Nonpathogen - endo-1,4-beta-glucanase Mext_2793 1 None None None 163854201 Nonpathogen - hypothetical protein Mext_4805 11 None None None 163853331 Common - amidophosphoribosyltransferase Mext_3932 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 163850427 Nonpathogen - TonB family protein Mext_0994 1 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 163851132 Common - isochorismatase hydrolase Mext_1705 138 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 163850734 Common - Camphor resistance CrcB protein Mext_1305 35 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 163849630 Common - tryptophan synthase, beta subunit Mext_0176 227 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 163854263 Common - Glutathione S-transferase domain Mext_4867 98 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163849497 Nonpathogen - hypothetical protein Mext_0041 1 COG4907 COG4907, Predicted membrane protein Function unknown 163852286 Common - gamma-glutamyl phosphate reductase Mext_2868 187 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 163850949 Common - regulatory protein TetR Mext_1522 70 COG1309 AcrR, Transcriptional regulator Transcription 163854033 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Mext_4637 206 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 163853987 Common - hypothetical protein Mext_4591 4 None None None 163852418 Common - protein of unknown function DUF218 Mext_3001 103 COG1434 COG1434, Uncharacterized conserved protein Function unknown 163851377 Nonpathogen - hypothetical protein Mext_1950 2 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 163853583 Common - hydrolase, TatD family Mext_4186 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 163853625 Common - protein-export membrane protein SecD Mext_4228 220 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 163852021 Common - recA protein Mext_2601 219 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 163852255 Common - CheW domain protein Mext_2837 26 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 163851664 Nonpathogen - hypothetical protein Mext_2241 1 None None None 163853690 Common - heat shock protein DnaJ domain protein Mext_4293 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 163849810 Nonpathogen - hypothetical protein Mext_0360 3 None None None 163851170 Common - Carbonate dehydratase Mext_1743 164 COG0583 LysR, Transcriptional regulator Transcription 163853727 Common - phospholipase D/Transphosphatidylase Mext_4330 27 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 163852411 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_2994 95 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163850070 Nonpathogen - hypothetical protein Mext_0628 1 None None None 163851727 Common - OsmC family protein Mext_2304 80 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 163853751 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Mext_4354 226 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 163852309 Common - pyruvate, phosphate dikinase Mext_2891 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 163853511 Common - ATP-binding region ATPase domain protein Mext_4113 117 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163851007 Common - tRNA modification GTPase TrmE Mext_1580 223 COG0486 ThdF, Predicted GTPase General function prediction only 163854046 Common - regulatory protein GntR HTH Mext_4650 138 COG1802 GntR, Transcriptional regulators Transcription 163850545 Nonpathogen - hypothetical protein Mext_1113 4 None None None 163849904 Nonpathogen - hypothetical protein Mext_0455 1 None None None 163849820 Common - ApaG domain protein Mext_0370 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 163850014 Common - binding-protein-dependent transport systems inner membrane component Mext_0571 140 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 163854107 Nonpathogen - hypothetical protein Mext_4711 1 None None None 163850746 Nonpathogen - hypothetical protein Mext_1317 10 None None None 163853997 Nonpathogen - hypothetical protein Mext_4601 1 None None None 163850465 Common - Methyltransferase type 11 Mext_1032 42 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 163851806 Common - PAS sensor protein Mext_2383 158 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163851258 Common - methenyltetrahydromethanopterin cyclohydrolase Mext_1831 27 COG3252 COG3252, Methenyltetrahydromethanopterin cyclohydrolase Coenzyme metabolism 163851345 Nonpathogen - hypothetical protein Mext_1918 1 None None None 163850162 Common - aldo/keto reductase Mext_0722 204 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 163853758 Common - ThiJ/PfpI domain protein Mext_4361 99 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 163852425 Common - protein of unknown function DUF192 Mext_3008 86 COG1430 COG1430, Uncharacterized conserved protein Function unknown 163850301 Common - hypothetical protein Mext_0868 20 None None None 163851755 Common - dethiobiotin synthase Mext_2332 149 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 163853588 Common - dTMP kinase Mext_4191 218 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 163851116 Common - diguanylate cyclase Mext_1689 178 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163853828 Common - ATP-binding region ATPase domain protein Mext_4432 222 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 163852104 Common - glycosyl transferase group 1 Mext_2685 223 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163851227 Common - succinyl-CoA synthetase, alpha subunit Mext_1800 206 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 163853454 Common - PilT protein domain protein Mext_4056 38 COG3744 COG3744, Uncharacterized protein conserved in bacteria Function unknown 163853256 Common - acriflavin resistance protein Mext_3856 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 163850438 Common - pseudouridine synthase, RluA family Mext_1005 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 163851812 Nonpathogen - hypothetical protein Mext_2389 5 None None None 163853329 Common - dihydrofolate reductase Mext_3930 2 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 163850431 Nonpathogen - hypothetical protein Mext_0998 4 None None None 163852983 Common - Hemolysin-type calcium-binding region Mext_3576 69 None None None 163850792 Common - regulatory protein DeoR Mext_1363 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 163853482 Nonpathogen - hypothetical protein Mext_4084 1 None None None 163851678 Common - PAS sensor protein Mext_2255 209 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 163853440 Common - hypothetical protein Mext_4042 13 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 163849986 Common - PAS sensor protein Mext_0543 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163852257 Common - response regulator receiver Mext_2839 222 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 163853816 Common - Patatin Mext_4420 11 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 163852690 Common - N-formylglutamate amidohydrolase Mext_3275 57 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 163852236 Common - TIM-barrel protein, nifR3 family Mext_2818 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 163853989 Common - AMP-dependent synthetase and ligase Mext_4593 200 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 163853652 Nonpathogen - hypothetical protein Mext_4255 1 None None None 163852400 Common - peptidase M23B Mext_2983 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 163852196 Common - hypothetical protein Mext_2777 44 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 163852180 Common - NAD(P)(+) transhydrogenase (AB-specific) Mext_2761 122 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 163852153 Nonpathogen - antenna complex alpha/beta subunit Mext_2734 9 None None None 163849717 Common - short-chain dehydrogenase/reductase SDR Mext_0265 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163853070 Common - Acyl-CoA dehydrogenase type 2 domain Mext_3664 86 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 163852939 Common - PAS fold-3 domain protein Mext_3528 44 None None None 163851870 Nonpathogen - hypothetical protein Mext_2447 1 None None None 163850158 Common - ethanolamine transproter Mext_0718 161 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 163851769 Common - ATP-dependent chaperone ClpB Mext_2346 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 163852118 Common - transcription termination factor NusA Mext_2699 219 COG0195 NusA, Transcription elongation factor Transcription 163850453 Nonpathogen - hypothetical protein Mext_1020 1 None None None 163849835 Nonpathogen - molybdopterin-guanine dinucleotide biosynthesis protein A Mext_0385 10 None None None 163853840 Common - FolC bifunctional protein Mext_4444 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 163850248 Common - ABC transporter related Mext_0815 247 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 163851094 Common - ATP-binding region ATPase domain protein Mext_1667 144 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 163850675 Common - glycosyl transferase family 51 Mext_1245 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 163854003 Nonpathogen - hypothetical protein Mext_4607 3 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 163853404 Common - aspartyl-tRNA synthetase Mext_4005 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163853733 Common - cytochrome o ubiquinol oxidase, subunit I Mext_4336 165 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 163850960 Common - Protein-glutamate O-methyltransferase Mext_1533 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 163854097 Nonpathogen - hypothetical protein Mext_4701 1 None None None 163852770 Common - hypothetical protein Mext_3355 14 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 163852677 Common - cytochrome c oxidase, subunit I Mext_3262 167 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 163852863 Common - Glutathione S-transferase domain Mext_3449 66 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163851574 Nonpathogen - hypothetical protein Mext_2151 3 None None None 163849979 Nonpathogen - hypothetical protein Mext_0536 1 None None None 163851923 Common - ABC transporter related Mext_2500 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 163850833 Common - protein of unknown function DUF1007 Mext_1404 35 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 163852482 Common - cation diffusion facilitator family transporter Mext_3065 180 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 163853740 Common - response regulator receiver Mext_4343 210 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 163849547 Common - dienelactone hydrolase Mext_0091 34 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 163851118 Common - xanthine permease Mext_1691 128 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 163853186 Nonpathogen - hypothetical protein Mext_3784 1 None None None 163849730 Common - pseudouridine synthase, RluA family Mext_0278 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 163851844 Nonpathogen - hypothetical protein Mext_2421 1 None None None 163850333 Common - Asparaginase/glutaminase Mext_0900 134 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 163851179 Nonpathogen - hypothetical protein Mext_1752 1 None None None 163849686 Common - potassium-transporting ATPase, A subunit Mext_0233 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 163851808 Common - domain of unknown function DUF1730 Mext_2385 135 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 163849818 Common - protein of unknown function UPF0187 Mext_0368 56 COG3781 COG3781, Predicted membrane protein Function unknown 163851301 Common - protein of unknown function DUF1376 Mext_1874 8 COG3756 COG3756, Uncharacterized protein conserved in bacteria Function unknown 163854005 Nonpathogen - hypothetical protein Mext_4609 1 None None None 163853922 Common - histidine kinase dimerisation/phosphoacceptor Mext_4526 105 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163851017 Common - conserved hypothetical proteinn Mext_1590 16 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 163851710 Common - carboxyl-terminal protease Mext_2287 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 163852986 Nonpathogen - hypothetical protein Mext_3580 3 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 163852393 Common - Leucyl aminopeptidase Mext_2976 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 163853369 Common - band 7 protein Mext_3970 11 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 163850141 Nonpathogen - hypothetical protein Mext_0701 1 None None None 163853885 Common - Glutathione S-transferase domain Mext_4489 105 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163850388 Common - peptide chain release factor 1 Mext_0955 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 163852327 Common - metallophosphoesterase Mext_2910 94 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 163851188 Common - methionine-R-sulfoxide reductase Mext_1761 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 163853035 Common - GAF domain protein Mext_3629 11 COG2203 FhlA, FOG: GAF domain Signal transduction mechanisms 163853496 Common - SNARE associated Golgi protein Mext_4098 11 COG0398 COG0398, Uncharacterized conserved protein Function unknown 163854236 Common - ATP-dependent metalloprotease FtsH Mext_4840 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 163849508 Common - Phosphate butyryltransferase Mext_0052 147 COG0280 Pta, Phosphotransacetylase Energy production and conversion 163851042 Common - metallophosphoesterase Mext_1615 27 COG4186 COG4186, Predicted phosphoesterase or phosphohydrolase General function prediction only 163849530 Common - response regulator receiver protein Mext_0074 26 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 163852267 Common - regulatory protein LysR Mext_2849 67 COG1910 COG1910, Periplasmic molybdate-binding protein/domain Inorganic ion transport and metabolism 163849610 Common - hypothetical protein Mext_0156 6 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 163851703 Common - hypothetical protein Mext_2280 6 None None None 163850991 Common - thiamine pyrophosphate protein domain protein TPP-binding Mext_1564 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 163853570 Common - glycosyl transferase family 39 Mext_4173 36 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 163849963 Common - putative cytochrome P460 Mext_0520 13 None None None 163849811 Common - peptidase S24 and S26 domain protein Mext_0361 122 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 163849981 Nonpathogen - hypothetical protein Mext_0538 1 None None None 163854181 Common - multiple antibiotic resistance (MarC)-related protein Mext_4785 157 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 163852807 Common - deoxyguanosinetriphosphate triphosphohydrolase Mext_3393 158 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 163852355 Nonpathogen - hypothetical protein Mext_2938 1 None None None 163850920 Common - maf protein Mext_1491 137 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 163850698 Common - septum site-determining protein MinD Mext_1268 141 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 163851644 Common - protease Do Mext_2221 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 163851522 Common - ammonium transporter Mext_2099 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 163853972 Common - DNA polymerase III, alpha subunit Mext_4576 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 163853042 Nonpathogen - hypothetical protein Mext_3636 1 None None None 163850064 Common - FlgA, flagellar basal-body P-ring formation protein Mext_0622 32 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 163852706 Common - hypothetical protein Mext_3291 23 None None None 163852765 Common - 4Fe-4S ferredoxin iron-sulfur binding domain protein Mext_3350 39 COG1146 COG1146, Ferredoxin Energy production and conversion 163853202 Nonpathogen - hypothetical protein Mext_3800 4 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 163852956 Nonpathogen - hypothetical protein Mext_3548 1 None None None 163850125 Common - flagellar hook-associated 3 family protein Mext_0685 20 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 163850989 Common - Smr protein/MutS2 Mext_1562 24 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 163853704 Common - hypothetical protein Mext_4307 16 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 163853464 Common - glycerol kinase Mext_4066 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 163852036 Common - protein of unknown function DUF162 Mext_2616 94 COG1139 COG1139, Uncharacterized conserved protein containing a ferredoxin-like domain Energy production and conversion 163852384 Common - cytidine deaminase Mext_2967 57 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 163850037 Common - ATP-binding region ATPase domain protein Mext_0595 180 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163850365 Nonpathogen - hypothetical protein Mext_0932 1 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 163852319 Nonpathogen - hypothetical protein Mext_2902 4 None None None 163854217 Common - PUCC protein Mext_4821 23 None None None 163850567 Nonpathogen - hypothetical protein Mext_1135 1 None None None 163850183 Common - protein of unknown function DUF955 Mext_0743 21 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 163852519 Common - protein of unknown function DUF1348 Mext_3103 49 COG3558 COG3558, Uncharacterized protein conserved in bacteria Function unknown 163850058 Nonpathogen - hypothetical protein Mext_0616 1 None None None 163850052 Common - RNA polymerase sigma factor RpoD Mext_0610 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 163851890 Common - ABC-2 type transporter Mext_2467 28 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 163853172 Common - Protein of unknown function DUF1790 Mext_3770 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 163851175 Common - diguanylate cyclase Mext_1748 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 163851527 Common - hypothetical protein Mext_2104 5 None None None 163852578 Common - 6,7-dimethyl-8-ribityllumazine synthase Mext_3162 211 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 163854012 Common - NADH dehydrogenase (quinone) Mext_4616 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 163853337 Common - replicative DNA helicase Mext_3938 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 163852966 Common - DegT/DnrJ/EryC1/StrS aminotransferase Mext_3558 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 163852906 Common - inner-membrane translocator Mext_3493 71 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 163849574 Nonpathogen - hypothetical protein Mext_0118 1 None None None 163853091 Nonpathogen - hypothetical protein Mext_3687 1 None None None 163850927 Common - tRNA synthetase class II (G H P and S) Mext_1498 42 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 163853104 Nonpathogen - hypothetical protein Mext_3700 1 None None None 163851953 Common - Deoxyribodipyrimidine photo-lyase Mext_2531 40 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 163851972 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Mext_2550 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 163853211 Nonpathogen - hypothetical protein Mext_3809 1 None None None 163853362 Common - polar amino acid ABC transporter, inner membrane subunit Mext_3963 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 163853546 Common - extracellular solute-binding protein family 3 Mext_4149 18 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 163854120 Common - cobalamin biosynthesis protein CobD Mext_4724 146 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 163850253 Common - chemotaxis sensory transducer Mext_0820 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163853805 Nonpathogen - hypothetical protein Mext_4409 1 None None None 163852187 Nonpathogen - hypothetical protein Mext_2768 1 None None None 163852786 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Mext_3372 69 COG0388 COG0388, Predicted amidohydrolase General function prediction only 163853353 Common - GCN5-related N-acetyltransferase Mext_3954 32 COG0456 RimI, Acetyltransferases General function prediction only 163850200 Common - hypothetical protein Mext_0760 15 None None None 163850400 Common - diguanylate cyclase Mext_0967 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163852304 Common - MgtC/SapB transporter Mext_2886 117 COG1285 SapB, Uncharacterized membrane protein Function unknown 163851877 Common - Alcohol dehydrogenase zinc-binding domain protein Mext_2454 176 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 163851336 Common - low molecular weight phosphotyrosine protein phosphatase Mext_1909 121 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 163851926 Common - PTS IIA-like nitrogen-regulatory protein PtsN Mext_2503 135 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 163851977 Common - chemotaxis sensory transducer Mext_2555 143 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 163851597 Common - regulatory protein MarR Mext_2174 141 COG1846 MarR, Transcriptional regulators Transcription 163853947 Common - protein of unknown function UPF0118 Mext_4551 76 COG0628 PerM, Predicted permease General function prediction only 163852672 Common - protein of unknown function DUF983 Mext_3257 29 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 163851419 Nonpathogen - hypothetical protein Mext_1992 1 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 163852935 Nonpathogen - hypothetical protein Mext_3524 1 None None None 163851165 Common - luciferase family protein Mext_1738 77 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 163849462 Common - Rv0623 family protein transcription factor Mext_0005 8 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 163852210 Nonpathogen - hypothetical protein Mext_2791 1 None None None 163849636 Common - ribosomal protein S1 Mext_0182 216 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 163851997 Common - beta-lactamase domain protein Mext_2576 217 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 163853199 Common - regulatory protein TetR Mext_3797 35 COG1309 AcrR, Transcriptional regulator Transcription 163850506 Common - proton-translocating NADH-quinone oxidoreductase, chain L Mext_1074 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 163850380 Common - diguanylate cyclase Mext_0947 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163851638 Common - putative proteasome-type protease Mext_2215 54 COG3484 COG3484, Predicted proteasome-type protease Posttranslational modification, protein turnover, chaperones 163851900 Nonpathogen - Flp/Fap pilin component Mext_2477 1 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 163851859 Common - CMP/dCMP deaminase zinc-binding Mext_2436 163 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 163851860 Nonpathogen - hypothetical protein Mext_2437 1 None None None 163849583 Nonpathogen - hypothetical protein Mext_0127 2 None None None 163852350 Common - hypothetical protein Mext_2933 45 COG0657 Aes, Esterase/lipase Lipid metabolism 163853381 Common - FeS assembly scaffold SufA Mext_3982 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 163853852 Common - beta-lactamase domain protein Mext_4456 33 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 163852636 Common - protein of unknown function DUF779 Mext_3221 41 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 163852533 Common - band 7 protein Mext_3117 35 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 163853270 Common - CMP/dCMP deaminase zinc-binding Mext_3870 200 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 163852452 Common - hypothetical protein Mext_3035 3 None None None 163852859 Common - cation efflux protein Mext_3445 55 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 163852175 Common - death-on-curing family protein Mext_2756 45 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 163851650 Common - diguanylate cyclase Mext_2227 181 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 163850209 Common - Hydroxypyruvate reductase Mext_0771 85 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 163852001 Nonpathogen - hypothetical protein Mext_2580 1 None None None 163849498 Nonpathogen - hypothetical protein Mext_0042 1 None None None 163853268 Common - alpha/beta hydrolase fold Mext_3868 138 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163850087 Common - heat shock protein HslVU, ATPase subunit HslU Mext_0645 211 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 163851551 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Mext_2128 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 163849784 Common - binding-protein-dependent transport systems inner membrane component Mext_0332 141 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163854223 Common - 6-phosphogluconolactonase Mext_4827 126 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 163852375 Common - oxidoreductase alpha (molybdopterin) subunit Mext_2958 173 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 163853436 Common - major facilitator superfamily MFS_1 Mext_4038 108 None None None 163853391 Nonpathogen - hypothetical protein Mext_3992 1 None None None 163849505 Common - sulphate transporter Mext_0049 141 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 163852715 Common - PAS sensor protein Mext_3300 118 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163850352 Common - ribonuclease T2 Mext_0919 46 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 163852169 Common - hypothetical protein Mext_2750 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 163852164 Common - porin Mext_2745 16 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 163850982 Common - histidyl-tRNA synthetase Mext_1555 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 163849882 Common - ROSMUCR transcriptional regulator Mext_0432 34 COG4957 COG4957, Predicted transcriptional regulator Transcription 163850919 Common - cation diffusion facilitator family transporter Mext_1490 167 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 163852790 Common - alpha/beta hydrolase fold Mext_3376 126 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 163852839 Common - Orn/DAP/Arg decarboxylase 2 Mext_3425 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 163853579 Common - histidine kinase dimerisation/phosphoacceptor Mext_4182 80 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 163850841 Nonpathogen - hypothetical protein Mext_1412 1 None None None 163851696 Common - signal peptidase I Mext_2273 212 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 163853559 Common - protein of unknown function DUF339 Mext_4162 38 COG2938 COG2938, Uncharacterized conserved protein Function unknown 163853552 Common - hypothetical protein Mext_4155 12 COG4329 COG4329, Predicted membrane protein Function unknown 163853085 Common - nucleotide sugar dehydrogenase Mext_3681 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 163849899 Nonpathogen - hypothetical protein Mext_0450 1 None None None 163851326 Nonpathogen - hypothetical protein Mext_1899 1 None None None 163849563 Common - hypothetical protein Mext_0107 11 None None None 163853398 Common - ribosomal protein L1 Mext_3999 241 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 163850108 Common - tRNA/rRNA methyltransferase (SpoU) Mext_0666 159 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 163850479 Common - ABC transporter related Mext_1046 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 163851831 Common - SapC family protein Mext_2408 26 None None None 163850550 Common - short-chain dehydrogenase/reductase SDR Mext_1118 65 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 163851554 Common - hypothetical protein Mext_2131 17 None None None 163849967 Common - hypothetical protein Mext_0524 11 None None None 163852338 Nonpathogen - hypothetical protein Mext_2921 1 None None None 163850514 Common - NADH dehydrogenase I, D subunit Mext_1082 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 163850651 Common - hypothetical protein Mext_1221 132 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 163851749 Common - lipoprotein signal peptidase Mext_2326 59 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 163852067 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_2647 87 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163853860 Nonpathogen - hypothetical protein Mext_4464 1 None None None 163853193 Common - short-chain dehydrogenase/reductase SDR Mext_3791 238 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 163852224 Common - Beta-ketoacyl-acyl-carrier-protein synthase I Mext_2805 209 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 163853445 Nonpathogen - hypothetical protein Mext_4047 1 None None None 163849985 Common - aminopeptidase N Mext_0542 160 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 163849516 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Mext_0060 30 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 163852059 Common - maleylacetoacetate isomerase Mext_2639 75 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 163852478 Common - sigma-54 factor interaction domain-containing protein Mext_3061 224 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 163852820 Common - binding-protein-dependent transport systems inner membrane component Mext_3406 194 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 163854022 Nonpathogen - hypothetical protein Mext_4626 1 None None None 163851390 Common - phosphoribosylaminoimidazole carboxylase, ATPase subunit Mext_1963 192 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 163852757 Common - Alkanesulfonate monooxygenase Mext_3342 72 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 163850135 Common - hypothetical protein Mext_0695 11 None None None 163853165 Common - Xylose isomerase domain protein TIM barrel Mext_3763 7 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 163852331 Nonpathogen - hypothetical protein Mext_2914 1 None None None 163850958 Common - response regulator receiver Mext_1531 222 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 163851857 Nonpathogen - hypothetical protein Mext_2434 1 None None None 163850535 Common - Na+/H+ antiporter NhaD and related arsenite permease-like protein Mext_1103 51 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 163850237 Common - phage uncharacterized protein Mext_0804 32 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 163852345 Common - periplasmic binding protein Mext_2928 98 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 163852444 Common - NAD-dependent epimerase/dehydratase Mext_3027 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163850687 Common - protein of unknown function DUF849 Mext_1257 26 COG3246 COG3246, Uncharacterized conserved protein Function unknown 163852913 Common - UspA domain protein Mext_3500 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 163849476 Common - Non-specific serine/threonine protein kinase Mext_0019 103 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 163854251 Common - GntR domain protein Mext_4855 116 COG1802 GntR, Transcriptional regulators Transcription 163851653 Common - ribonuclease BN Mext_2230 59 COG1295 Rbn, Predicted membrane protein Function unknown 163852886 Common - hypothetical protein Mext_3473 19 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 163850758 Common - PAS sensor protein Mext_1329 195 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 163851530 Common - protein of unknown function DUF952 Mext_2107 45 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 163853135 Common - Substrate-binding region of ABC-type glycine betaine transport system Mext_3733 84 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 163851565 Nonpathogen - hypothetical protein Mext_2142 1 None None None 163852085 Nonpathogen - hypothetical protein Mext_2665 1 None None None 163849593 Common - TadE family protein Mext_0138 8 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 163850902 Common - Uracil-DNA glycosylase superfamily Mext_1473 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 163852062 Nonpathogen - hypothetical protein Mext_2642 1 None None None 163850095 Common - ribosomal protein S16 Mext_0653 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 163853379 Common - cysteine desulfurase, SufS subfamily Mext_3980 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 163853895 Nonpathogen - hypothetical protein Mext_4499 1 None None None 163849889 Nonpathogen - hypothetical protein Mext_0439 1 None None None 163852915 Common - transport-associated Mext_3502 6 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 163851968 Nonpathogen - hypothetical protein Mext_2546 3 None None None 163852800 Common - hypothetical protein Mext_3386 4 COG3904 COG3904, Predicted periplasmic protein Function unknown 163852198 Common - Chloride channel core Mext_2779 67 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 163852016 Common - protein of unknown function DUF179 Mext_2596 129 COG1678 COG1678, Putative transcriptional regulator Transcription 163852584 Common - riboflavin biosynthesis protein RibD Mext_3168 225 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 163852427 Common - magnesium chelatase accessory protein Mext_3010 87 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 163852615 Common - GCN5-related N-acetyltransferase Mext_3200 138 COG0456 RimI, Acetyltransferases General function prediction only 163853307 Common - addiction module antitoxin, RelB/DinJ family Mext_3908 41 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 163851689 Common - nitrogen-fixing NifU domain protein Mext_2266 42 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 163853038 Common - hypothetical protein Mext_3632 8 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 163853101 Common - transposase and inactivated derivatives-like protein Mext_3697 43 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 163853258 Common - NADP oxidoreductase coenzyme F420-dependent Mext_3858 42 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 163852845 Common - Adenine deaminase Mext_3431 68 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 163853936 Common - LysR substrate-binding Mext_4540 169 COG0583 LysR, Transcriptional regulator Transcription 163849554 Common - extracellular solute-binding protein family 3 Mext_0098 18 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 163853115 Common - methyltransferase FkbM family Mext_3712 24 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 163853420 Common - NmrA family protein Mext_4022 75 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163852242 Common - RNA chaperone Hfq Mext_2824 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 163853734 Common - ubiquinol oxidase, subunit II Mext_4337 126 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 163849641 Common - cytochrome c biogenesis protein transmembrane region Mext_0187 17 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 163851295 Nonpathogen - hypothetical protein Mext_1868 1 None None None 163849643 Nonpathogen - hypothetical protein Mext_0189 1 None None None 163852298 Common - ErfK/YbiS/YcfS/YnhG family protein Mext_2880 89 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 163853372 Common - protein of unknown function DUF891 Mext_3973 21 COG4679 COG4679, Phage-related protein Function unknown 163849998 Nonpathogen - hypothetical protein Mext_0555 1 None None None 163852597 Common - rare lipoprotein A Mext_3182 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 163852590 Common - ATP synthase F0, A subunit Mext_3175 206 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 163853079 Nonpathogen - phosphohydrolase (DHH superfamily)-like protein Mext_3673 2 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 163852026 Common - flagellar hook-basal body complex subunit FliE Mext_2606 36 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 163849798 Common - AMP-dependent synthetase and ligase Mext_0346 218 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 163850405 Nonpathogen - hypothetical protein Mext_0972 1 None None None 163851453 Nonpathogen - hypothetical protein Mext_2029 1 None None None 163851814 Common - hypothetical protein Mext_2391 21 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 163853611 Common - protein of unknown function UPF0118 Mext_4214 184 COG0628 PerM, Predicted permease General function prediction only 163851732 Common - conserved hypothetical proteinn Mext_2309 15 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 163854103 Common - carbohydrate kinase, YjeF related protein Mext_4707 210 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 163851244 Common - coenzyme PQQ biosynthesis protein E Mext_1817 106 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 163854110 Common - phosphate ABC transporter, inner membrane subunit PstC Mext_4714 225 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 163850528 Common - acetyl-CoA carboxylase, biotin carboxylase Mext_1096 236 COG0439 AccC, Biotin carboxylase Lipid metabolism 163853853 Common - protein of unknown function DUF949 Mext_4457 52 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 163850769 Common - major facilitator superfamily MFS_1 Mext_1340 185 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163851096 Common - esterase/lipase-like protein Mext_1669 72 COG0657 Aes, Esterase/lipase Lipid metabolism 163849936 Common - hypothetical protein Mext_0492 7 None None None 163850359 Common - hypothetical protein Mext_0926 14 COG5436 COG5436, Predicted integral membrane protein Function unknown 163851421 Common - beta-lactamase domain protein Mext_1994 112 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 163851803 Common - ribonuclease R Mext_2380 192 COG0557 VacB, Exoribonuclease R Transcription 163851884 Common - glycosyl transferase group 1 Mext_2461 46 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 163851203 Common - beta-lactamase domain protein Mext_1776 69 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 163851713 Common - General substrate transporter Mext_2290 128 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 163850893 Common - Polynucleotide adenylyltransferase region Mext_1464 177 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 163850440 Common - NADH dehydrogenase Mext_1007 119 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 163850500 Common - protein of unknown function DUF1467 Mext_1068 11 COG5454 COG5454, Predicted secreted protein Function unknown 163851033 Common - hypothetical protein Mext_1606 8 None None None 163852829 Common - transglutaminase domain protein Mext_3415 77 COG4196 COG4196, Uncharacterized protein conserved in bacteria Function unknown 163849595 Nonpathogen - hypothetical protein Mext_0140 1 None None None 163852600 Common - ABC transporter related Mext_3185 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 163850685 Common - hypothetical protein Mext_1255 33 COG3247 HdeD, Uncharacterized conserved protein Function unknown 163852696 Common - peptide methionine sulfoxide reductase Mext_3281 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 163851432 Common - TonB-dependent siderophore receptor Mext_2005 106 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 163852136 Common - radical SAM domain protein Mext_2717 17 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 163853129 Common - Creatininase Mext_3727 81 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 163849726 Common - DEAD/DEAH box helicase domain protein Mext_0274 113 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 163850449 Common - Alcohol dehydrogenase GroES domain protein Mext_1016 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 163851446 Common - LemA family protein Mext_2020 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 163852624 Nonpathogen - hypothetical protein Mext_3209 1 COG4371 COG4371, Predicted membrane protein Function unknown 163853738 Common - efflux transporter, RND family, MFP subunit Mext_4341 156 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 163854284 Common - phage/plasmid primase, P4 family Mext_4888 51 COG3378 COG3378, Predicted ATPase General function prediction only 163852687 Common - lytic murein transglycosylase Mext_3272 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 163853628 Common - peptidase M23B Mext_4231 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 163853601 Common - D-lactate dehydrogenase (cytochrome) Mext_4204 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 163852663 Common - hypothetical protein Mext_3248 5 None None None 163850470 Common - LysR substrate-binding Mext_1037 121 COG0583 LysR, Transcriptional regulator Transcription 163852079 Common - Dihydrofolate reductase Mext_2659 143 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 163853248 Common - Acyl-CoA dehydrogenase type 2 domain Mext_3848 24 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism