Campylobacter concisus 13826, complete genome NC_009802 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 157164604 Pathogen - arylsulfotransferase CCC13826_2223 1 None None None 157164847 Common - hypothetical protein CCC13826_0046 10 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 157164997 Common - flagellum-specific ATP synthase CCC13826_0283 22 None None None 157165241 Common - pyruvate-ferredoxin oxidoreductase CCC13826_1705 220 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 157164237 Common - riboflavin biosynthesis protein ribAB CCC13826_1973 89 COG0348 NapH, Polyferredoxin Energy production and conversion 157165208 Common secG protein translocation protein, low temperature CCC13826_0774 5 COG3399 COG3399, Uncharacterized protein conserved in bacteria Function unknown 157165764 Common - sodium:neurotransmitter symporter family CCC13826_1706 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 157165563 Common - hypothetical protein CCC13826_1003 72 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 157164254 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) CCC13826_1761 223 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 157165148 Common - polysaccharide biosynthesis protein CCC13826_0458 10 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 157164274 Common hydD quinone-reactive Ni/Fe hydrogenase CCC13826_1123 20 None None None 157163969 Common - hypothetical protein CCC13826_1847 3 None None None 157165102 Common wlaD putative glycosyltransferase CCC13826_1008 130 COG1802 GntR, Transcriptional regulators Transcription 157164243 Pathogen - hypothetical protein CCC13826_1714 2 None None None 157164215 Common - formate dehydrogenase iron-sulfur subunit CCC13826_1667 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 157164611 Common - L-fuculose-1-phosphate aldolase CCC13826_1084 6 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 157164874 Common - 2,3-bisphosphoglycerate-independent phosphoglycerate mutase CCC13826_1555 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 157165111 Common - TrkA-C domain protein CCC13826_0088 10 COG3400 COG3400, Uncharacterized protein conserved in bacteria Function unknown 157164836 Common leuS leucyl-tRNA synthetase CCC13826_0074 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157163908 Common - methyltransferase GidB (Glucose-inhibited divisionprotein B) CCC13826_0882 175 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 157164693 Common - radical SAM domain protein CCC13826_1654 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 157164342 Common rpoZ DNA-directed RNA polymerase, omega subunit CCC13826_0501 8 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 157165731 Common - hypothetical protein CCC13826_0709 22 None None None 157165122 Common putP sodium/proline symporter CCC13826_0416 143 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 157164642 Pathogen - hypothetical protein CCC13826_1573 1 None None None 157165465 Pathogen - hypothetical protein CCC13826_1175 2 None None None 157164882 Common glmS glucosamine fructose-6-phosphate aminotransferase (isomerizing) CCC13826_0404 44 COG1159 Era, GTPase General function prediction only 157164179 Pathogen - putative phosphonate uptake transporter CCC13826_2279 1 None None None 157164383 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase CCC13826_2096 147 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 157164106 Pathogen nrtD nitrate transport protein NrtD CCC13826_1949 1 None None None 157165526 Common - general glycosylation pathway protein CCC13826_1001 24 COG3875 COG3875, Uncharacterized conserved protein Function unknown 157165744 Common - methyl-accepting chemotaxis protein CCC13826_1233 74 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 157164575 Common - hypothetical protein CCC13826_1922 193 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 157163985 Common - hypothetical protein CCC13826_1010 3 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 157163906 Common - N-acylneuraminate cytidylyltransferase CCC13826_2299 69 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 157165344 Common - hypothetical protein CCC13826_1141 3 None None None 157163954 Common - glutathionylspermidine synthase subfamily CCC13826_1647 54 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 157164562 Common - NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 superfamily CCC13826_1656 145 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 157164339 Common fliP flagellar biosynthetic protein FliP CCC13826_0689 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 157165758 Common ftsA cell division protein FtsA CCC13826_1086 179 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 157164509 Common - hypothetical protein CCC13826_0891 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 157164422 Common - bacterial regulatory protein, AsnC family:Bacterial regulatory protein, GntR family CCC13826_1232 149 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 157164540 Common - tRNA nucleotidyltransferase/poly(A) polymerase family protein CCC13826_0039 212 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 157165395 Pathogen - hypothetical protein CCC13826_0031 1 None None None 157164347 Common - beta-lactamase HcpA (Cysteine-rich 28 kDaprotein) CCC13826_2205 5 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 157165118 Common - FO synthase subunit 2 (7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2) CCC13826_0447 184 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 157164931 Common ilvH acetolactate synthase small subunit CCC13826_1162 119 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 157165157 Common uvrA excinuclease ABC, A subunit CCC13826_0992 239 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 157164549 Pathogen - hypothetical protein CCC13826_1189 1 None None None 157164281 Common - hypothetical protein CCC13826_1725 5 COG2863 COG2863, Cytochrome c553 Energy production and conversion 157165259 Common - oxidoreductase family, NAD-binding Rossmann fold protein CCC13826_2300 47 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 157165022 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase CCC13826_1297 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 157165487 Common - PP-loop family CCC13826_0928 149 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 157165278 Common - hypothetical protein CCC13826_1437 46 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 157164635 Common - IspD/IspF bifunctional enzyme CCC13826_0390 37 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 157164948 Pathogen - hypothetical protein CCC13826_0734 1 None None None 157164736 Common - isoleucyl-tRNA synthetase (Isoleucine--tRNA ligase; IleRS) CCC13826_0717 3 None None None 157165003 Common uvrB excinuclease ABC, B subunit CCC13826_0674 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 157164366 Common map methionine aminopeptidase, type I CCC13826_1756 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 157163948 Common - nucleoside diphosphate kinase (NDK; NDP kinase; Nucleoside-2-P kinase) CCC13826_0990 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 157164008 Common - putative pyridine nucleotide-disulphide oxidoreductase CCC13826_0743 141 COG2081 COG2081, Predicted flavoproteins General function prediction only 157164649 Common - putative two-component sensor CCC13826_0820 127 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 157164865 Common - chlorohydrolase CCC13826_0371 89 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 157163941 Common - hypothetical protein CCC13826_1330 7 None None None 157164391 Common fecD iron chelatin ABC transporter, permease protein CCC13826_0452 9 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 157163929 Common - inner membrane protein YicO CCC13826_1484 134 COG2252 COG2252, Permeases General function prediction only 157165681 Common - hypothetical protein CCC13826_1338 7 None None None 157165635 Pathogen - FdhC protein CCC13826_1462 1 None None None 157165691 Common - C4-dicarboxylate-binding periplasmic protein CCC13826_0764 25 COG3470 Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport Inorganic ion transport and metabolism 157165271 Common - arginyl-tRNA synthetase (Arginine--tRNA ligase; ArgRS) CCC13826_1535 72 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 157165314 Common - thiamine biosynthesis protein ThiC CCC13826_0391 215 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 157165088 Common - transcriptional regulator, TraR/DksA family CCC13826_0939 132 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 157164206 Common rimM 16S rRNA processing protein RimM CCC13826_1431 37 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 157165568 Common era GTP-binding protein Era CCC13826_1223 219 COG1159 Era, GTPase General function prediction only 157164510 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA CCC13826_2318 28 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 157165618 Common - orotate phosphoribosyltransferase (oprt; oprtase) CCC13826_2089 102 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 157164174 Common - hypothetical protein CCC13826_0019 92 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 157165730 Common - radical SAM domain protein CCC13826_1972 72 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 157165295 Common - RmuC domain protein CCC13826_0751 129 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 157164126 Common - antibiotic biosynthesis monooxygenase domain protein CCC13826_1905 8 COG1359 COG1359, Uncharacterized conserved protein Function unknown 157164613 Common trmD tRNA (guanine-N1)-methyltransferase CCC13826_1430 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 157165062 Common rplC ribosomal protein L3 CCC13826_2326 216 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 157164790 Common - hypothetical protein CCC13826_0322 2 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 157165204 Common ruvB holliday junction DNA helicase RuvB CCC13826_0384 236 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 157164720 Common - hypothetical protein CCC13826_1318 2 None None None 157164911 Common - putative periplasmic protein CCC13826_0243 33 None None None 157165379 Common - peptidyl-prolyl cis-trans isomerase B (PPIase B; Rotamase B) CCC13826_1513 199 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 157164972 Common rpsD ribosomal protein S4 CCC13826_1752 247 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 157164667 Common - L-cystine import ATP-binding protein TcyC CCC13826_1700 147 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 157164071 Common - putative peptidyl-prolyl cis-trans isomerase, fkbp-type CCC13826_0925 122 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 157165579 Common gltX glutamyl-tRNA synthetase CCC13826_0242 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 157164695 Common efp translation elongation factor P CCC13826_1570 221 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 157164168 Common purM phosphoribosylformylglycinamidine cyclo-ligase CCC13826_1844 231 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 157163856 Common - 1-aminocyclopropane-1-carboxylate deaminase CCC13826_2073 17 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 157164764 Common - transcriptional regulator, Fur family CCC13826_1383 169 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 157164164 Common - dihydroorotase (DHOase) CCC13826_0308 2 None None None 157164727 Common - RNA methyltransferase, TrmH family CCC13826_0040 161 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 157165650 Common - hypothetical protein CCC13826_0940 157 COG1576 COG1576, Uncharacterized conserved protein Function unknown 157165372 Common - udp-N-acetylglucosamine--n-acetylmuramyl-(pentapeptide)pyrophosphoryl-undecaprenol n-acetylglucosamine transferase (undecaprenyl-pp-murnac-pentapeptide-udpglcnac glcnactransferase) CCC13826_0577 185 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 157165434 Common - translocator protein, LysE family CCC13826_1449 78 COG1279 COG1279, Lysine efflux permease General function prediction only 157164135 Common - hypothetical protein CCC13826_1151 16 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 157165449 Pathogen - hypothetical protein CCC13826_2248 1 None None None 157164284 Common - hypothetical protein CCC13826_0989 7 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 157164003 Pathogen - hypothetical protein CCC13826_0676 1 None None None 157163899 Common - HIT family protein CCC13826_0482 63 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 157165249 Common crcB CrcB protein CCC13826_2292 129 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 157165139 Common - hypothetical protein CCC13826_0146 13 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 157164818 Pathogen - hypothetical protein CCC13826_1183 2 None None None 157164457 Common - orotidine 5'-phosphate decarboxylase CCC13826_0659 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 157165036 Common - protein YabJ CCC13826_0204 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 157164433 Common - putative periplasmic protein CCC13826_0921 3 COG5373 COG5373, Predicted membrane protein Function unknown 157165774 Common - putative flagellar hook capping protein CCC13826_1122 116 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 157165322 Common - hypothetical protein CCC13826_0049 182 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 157165698 Common - putative ftsk/spoiiie family CCC13826_1302 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 157164821 Pathogen - DNA polymerase III subunit alpha CCC13826_0930 1 None None None 157164228 Pathogen - hypothetical protein CCC13826_0191 1 COG4128 Zot, Zonula occludens toxin General function prediction only 157165597 Common - crispr-associated protein Cas2 CCC13826_1965 47 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 157164629 Common tuf translation elongation factor Tu CCC13826_0166 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 157164811 Common - ferredoxin, 4Fe-4S CCC13826_1213 74 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 157165476 Common purB adenylosuccinate lyase CCC13826_1894 239 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 157164438 Common - hypothetical protein CCC13826_0824 5 None None None 157165084 Common - sensory box/ggdef domain/hd domain protein CCC13826_0185 2 None None None 157164598 Pathogen - hypothetical protein CCC13826_0307 1 None None None 157165074 Pathogen - hypothetical protein CCC13826_0817 1 None None None 157164674 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 family protein CCC13826_1280 55 None None None 157164778 Common - Mug G:T/U mismatch-specific DNA glycosylase CCC13826_1935 47 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 157163895 Common - hypothetical protein CCC13826_0262 1 None None None 157164458 Common - response regulator receiver domain protein CCC13826_1063 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157164979 Common - dimethyladenosine transferase CCC13826_2284 42 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 157164486 Pathogen - hypothetical protein CCC13826_0008 1 None None None 157164710 Common - putative molybdenum cofactor synthesis domain CCC13826_1350 188 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 157164784 Common - translocator protein, LysE family CCC13826_0032 108 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 157165324 Pathogen - hypothetical protein CCC13826_2074 1 None None None 157163911 Common - bacterial type II and III secretion system protein CCC13826_0190 49 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 157164717 Common - SsrA-binding protein CCC13826_1795 9 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 157164886 Common - putative outer membrane protein CCC13826_0288 1 None None None 157164697 Common pgk phosphoglycerate kinase CCC13826_0515 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 157165510 Common - putative bacterial transcription activator, effector binding domain CCC13826_1440 24 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 157164198 Common - hypothetical protein CCC13826_1381 23 COG2930 COG2930, Uncharacterized conserved protein Function unknown 157164089 Common azlD branched-chain amino acid transport protein CCC13826_1827 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 157164092 Pathogen - biopolymer transport ExbD protein CCC13826_0828 1 None None None 157163924 Common - phosphomethylpyrimidine kinase superfamily CCC13826_0011 223 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 157164662 Common - methyl-accepting chemotaxis sensory transducer CCC13826_0585 78 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 157163864 Common - phosphate transporter family protein CCC13826_1218 172 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 157164805 Common rpsB ribosomal protein S2 CCC13826_0551 226 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 157165168 Common cas crispr-associated protein Cas5 CCC13826_1421 10 COG1688 COG1688, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 157164451 Common - cytochrome c oxidase, Cbb3-type, CcoQ subunit CCC13826_0725 7 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 157164627 Common secD protein-export membrane protein SecD CCC13826_0071 217 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 157165380 Pathogen - hypothetical protein CCC13826_0006 1 None None None 157164766 Common - peptidase family S51 CCC13826_0798 28 COG3340 PepE, Peptidase E Amino acid transport and metabolism 157165076 Common sugE SugE protein CCC13826_0662 157 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 157164496 Pathogen - hypothetical protein CCC13826_1826 2 None None None 157165705 Common - hypothetical protein CCC13826_0829 4 None None None 157164825 Common - Ser/Thr protein phosphatase family protein CCC13826_1327 95 None None None 157165307 Common - diguanylate cyclase (ggdef) domain protein CCC13826_1782 12 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 157164305 Common - ribonucleoside-diphosphate reductase, beta subunit CCC13826_0297 156 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 157165385 Common - protein TonB CCC13826_0827 4 None None None 157164058 Pathogen - polyphosphate kinase 2 CCC13826_0290 1 None None None 157165530 Pathogen - Hit family protein CCC13826_1166 1 None None None 157165181 Common yvfE pyridoxal phosphate-dependent enzyme CCC13826_1000 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 157164102 Common - putative Cell division protease FtsH homolog CCC13826_0993 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157163943 Common - glycoprotease family CCC13826_0417 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 157164398 Common - ABC-type transport system involved in multi-copper enzyme maturation, permease component CCC13826_0227 5 None None None 157164586 Common - PepSY-associated TM helix family CCC13826_2016 16 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 157164620 Common - tRNA synthetase, class II CCC13826_2132 53 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157164652 Common - hypothetical protein CCC13826_0433 11 None None None 157165545 Common - hypothetical protein CCC13826_1230 2 None None None 157165357 Common - ribosomal protein S1 CCC13826_0487 33 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 157165283 Common - Cpp22 CCC13826_1601 23 COG0730 COG0730, Predicted permeases General function prediction only 157164324 Common - YbaK CCC13826_2133 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 157164145 Pathogen - electron transport protein HydN CCC13826_2311 1 None None None 157164962 Common - elongation factor P (EF-P) CCC13826_0490 94 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 157164859 Common - bacterial extracellular solute-binding protein, family 3 CCC13826_1925 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 157164993 Pathogen hspR putative heat shock protein CCC13826_1291 1 None None None 157164444 Pathogen - hypothetical protein CCC13826_1811 2 None None None 157165042 Pathogen - hypothetical protein CCC13826_2057 1 None None None 157165402 Common - transcriptional regulator, TetR family protein CCC13826_1641 89 COG1309 AcrR, Transcriptional regulator Transcription 157165256 Common - hypothetical protein CCC13826_1947 1 None None None 157165581 Common - hypothetical protein CCC13826_0512 8 None None None 157165397 Common proS prolyl-tRNA synthetase CCC13826_1050 243 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157164079 Common - ATP synthase subunit B CCC13826_0913 21 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 157165105 Common secA preprotein translocase, SecA subunit CCC13826_1072 217 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 157164024 Common - hypothetical protein CCC13826_0097 6 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 157164114 Common - hypothetical protein CCC13826_0205 7 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 157165092 Common petA ubiquinol-Cytochrome c reductase, iron-sulfur subunit CCC13826_1921 120 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 157164158 Pathogen - putative ATP CCC13826_0955 1 None None None 157164758 Common - multidrug resistance protein MdtF CCC13826_1639 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 157165540 Common asnB asparagine synthase (glutamine-hydrolyzing) CCC13826_0524 155 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 157165644 Common - hypothetical protein CCC13826_1923 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 157164779 Pathogen - hypothetical protein CCC13826_0215 1 None None None 157165557 Common - hydrogenase maturation protease superfamily CCC13826_0715 21 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 157164945 Common - DNA-binding protein HU 1 (DNA-binding protein II; HB) CCC13826_0021 179 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 157164742 Common - hypothetical protein CCC13826_1733 20 None None None 157165095 Common - phosphate acetyltransferase (Phosphotransacetylase) CCC13826_1128 127 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 157164872 Common - citrate transporter superfamily CCC13826_1865 29 COG2056 COG2056, Predicted permease General function prediction only 157164418 Pathogen - hypothetical protein CCC13826_0305 1 None None None 157164141 Common - L(+)-tartrate dehydratase subunit beta (L-TTD beta) CCC13826_1231 219 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 157165576 Common - hydroxylamine reductase (Hybrid-cluster protein; HCP) CCC13826_0460 8 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 157164122 Common dnaN DNA polymerase III, beta subunit CCC13826_1851 206 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 157165365 Pathogen - hypothetical protein CCC13826_1917 1 None None None 157164138 Common - peptidyl-tRNA hydrolase (PTH) CCC13826_0506 172 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 157164743 Common - 3-isopropylmalate dehydratase small subunit CCC13826_0035 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 157163996 Common - hypothetical protein CCC13826_1458 1 None None None 157164062 Common ccoP cytochrome c oxidase, Cbb3-type, subunit III CCC13826_0726 69 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 157165470 Common - endonuclease III CCC13826_0080 82 COG2231 COG2231, Uncharacterized protein related to Endonuclease III DNA replication, recombination, and repair 157164672 Common frr ribosome recycling factor CCC13826_0341 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 157164082 Common fbcF ubiquinol Cytochrome c oxidoreductase, Rieske 2Fe-2S subunit CCC13826_2317 12 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 157164405 Common - putative Hsp90 protein CCC13826_1348 150 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 157164184 Common - hypothetical protein CCC13826_2304 133 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 157165724 Common murD UDP-N-acetylmuramoylalanine--D-glutamate ligase CCC13826_0566 206 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 157165606 Common - silent information regulator protein Sir2 CCC13826_1630 129 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 157164244 Common - putative cytoChrome c subfamily CCC13826_1919 14 COG2857 CYT1, Cytochrome c1 Energy production and conversion 157165390 Common rpsF ribosomal protein S6 CCC13826_1998 206 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 157164899 Pathogen - DNA helicase related protein CCC13826_2285 1 None None None 157164186 Pathogen - hypothetical protein CCC13826_1037 1 None None None 157164936 Common - type III pantothenate kinase (Pantothenic acid kinase; PanK-III) CCC13826_0217 26 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 157165261 Pathogen - hypothetical protein CCC13826_0934 1 None None None 157164375 Common exbB TonB-system energizer ExbB CCC13826_0394 146 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 157164370 Common rfaF ADP-heptose-lps heptosyltransferase II CCC13826_0924 13 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 157165677 Common - putative molybdenum ABC transporter, periplasmic binding protein CCC13826_1902 158 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 157164680 Common - cell division protein FtsX CCC13826_0504 13 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 157164926 Common panB ketopantoate hydroxymethyltransferase CCC13826_0813 7 None None None 157165486 Common - molybdenum-pterin binding domain protein CCC13826_2203 94 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 157165663 Common asnB asparagine synthase (glutamine-hydrolyzing) CCC13826_0536 168 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 157165155 Pathogen - twin-arginine translocation pathway signal CCC13826_0234 1 None None None 157163973 Common rpsP ribosomal protein S16 CCC13826_1433 206 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 157165450 Common - hypothetical protein CCC13826_0517 113 COG2855 COG2855, Predicted membrane protein Function unknown 157164507 Pathogen - hypothetical protein CCC13826_2334 1 None None None 157165409 Pathogen - type VI secretion lipoprotein, family CCC13826_1177 2 COG3521 COG3521, Uncharacterized protein conserved in bacteria Function unknown 157165637 Pathogen - hypothetical protein CCC13826_0106 1 None None None 157164316 Pathogen - hypothetical protein CCC13826_0654 1 None None None 157164797 Pathogen - hypothetical protein CCC13826_0402 1 None None None 157165516 Pathogen - hypothetical protein CCC13826_0904 1 None None None 157164906 Common hemB delta-aminolevulinic acid dehydratase CCC13826_0884 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 157165053 Common ybaK YbaK/ebsC protein CCC13826_1378 112 COG2606 EbsC, Uncharacterized conserved protein Function unknown 157164588 Common - putative permease CCC13826_0866 72 COG0348 NapH, Polyferredoxin Energy production and conversion 157165714 Common - ggdef domain protein CCC13826_0076 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 157164334 Pathogen - hypothetical protein CCC13826_1689 1 None None None 157164531 Common lepA GTP-binding protein LepA CCC13826_0855 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 157164086 Common - RNA methyltransferase, TrmH family CCC13826_1388 6 None None None 157164349 Common - hypothetical protein CCC13826_0418 9 COG3608 COG3608, Predicted deacylase General function prediction only 157165393 Common tag DNA-3-methyladenine glycosylase I CCC13826_0711 191 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 157164006 Common pyk pyruvate kinase CCC13826_0964 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 157165221 Common - MraY CCC13826_1556 56 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 157164043 Common - transcriptional regulatory protein, C CCC13826_0590 5 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157165696 Pathogen - hypothetical protein CCC13826_0343 3 None None None 157165648 Common hemD uroporphyrinogen-III synthase CCC13826_0493 8 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 157164360 Common trpB tryptophan synthase, beta subunit CCC13826_0972 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 157164545 Pathogen - hypothetical protein CCC13826_2055 1 None None None 157164542 Common cadF outer membrane fibronectin-binding protein CCC13826_1485 54 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 157165419 Common hypF [NiFe] hydrogenase maturation protein HypF CCC13826_0356 113 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 157164933 Common - site-specific recombinase, phage integrase family protein CCC13826_2082 88 COG0582 XerC, Integrase DNA replication, recombination, and repair 157164841 Common - hypothetical protein CCC13826_0546 2 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 157165130 Common - putative integral membrane protein CCC13826_2154 4 None None None 157164633 Common - tRNA (guanine-N(1)-)-methyltransferase CCC13826_1959 11 COG4105 ComL, DNA uptake lipoprotein General function prediction only 157165159 Common - hypothetical protein CCC13826_1518 2 None None None 157164209 Pathogen - tRNA(Ile)-lysidine synthase CCC13826_1571 1 None None None 157165152 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase CCC13826_1794 26 COG0824 FcbC, Predicted thioesterase General function prediction only 157164904 Common - hydrolase, carbon-nitrogen family CCC13826_0712 191 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 157165024 Common - formate dehydrogenase, cytochrome B subunit CCC13826_2138 65 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 157165001 Common - putative domain of unknown function CCC13826_0123 97 COG0628 PerM, Predicted permease General function prediction only 157163873 Common - HIT family protein CCC13826_0380 53 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 157164984 Common - lipoprotein CCC13826_0443 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 157164606 Pathogen - hd/hdig/kh domain protein CCC13826_2183 1 None None None 157164217 Common rpsC ribosomal protein S3 CCC13826_1771 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 157164848 Pathogen - RecA CCC13826_1909 3 None None None 157164177 Common nhaA Na+/H+ antiporter NhaA CCC13826_0732 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 157164600 Common aroK shikimate kinase CCC13826_0776 197 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 157164223 Common flaG FlaG protein CCC13826_1034 10 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 157163983 Common - asparate kinase, monofunctional class CCC13826_2018 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 157164538 Common coaE dephospho-CoA kinase CCC13826_1842 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 157164208 Common alaS alanyl-tRNA synthetase CCC13826_0051 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157164211 Common - hydrogenase expression/synthesis, HypA CCC13826_0103 165 COG0280 Pta, Phosphotransacetylase Energy production and conversion 157165146 Common - hypothetical protein CCC13826_1401 1 None None None 157164409 Common rarD RarD protein CCC13826_0152 100 COG2962 RarD, Predicted permeases General function prediction only 157165718 Common - succinate dehydrogenase, iron-sulfur protein subunit CCC13826_0048 206 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 157164707 Common - ABC transporter, permease protein CCC13826_0233 195 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 157163967 Common - aspartate racemase CCC13826_1511 83 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 157164591 Pathogen - 50S ribosomal protein L5 (BL6) CCC13826_0271 1 None None None 157165620 Common purH bifunctional purine biosynthesis protein PurH CCC13826_1632 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 157164385 Common - putative auxiliary transport protein, membrane fusion protein (MFP) family CCC13826_1256 179 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 157165247 Pathogen - hypothetical protein CCC13826_1879 1 None None None 157165595 Common pgpA phosphatidylglycerophosphatase A CCC13826_1464 93 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 157164108 Common - hypothetical protein CCC13826_0740 180 COG0546 Gph, Predicted phosphatases General function prediction only 157164577 Common amaA acid membrane antigen A CCC13826_0816 34 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 157165176 Common - hypothetical protein CCC13826_0959 3 None None None 157164210 Common - hypothetical protein CCC13826_0594 4 None None None 157165120 Pathogen - 3-oxoacyl-[acyl-carrier-protein] synthase 3 CCC13826_1208 1 None None None 157164471 Pathogen - hypothetical protein CCC13826_1382 1 None None None 157164880 Common - hypothetical protein CCC13826_1390 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 157164272 Common - RNA methyltransferase, TrmH family, group 3 CCC13826_1148 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 157163858 Common - ATP-utilizing enzyme of the pp-loop superfamily CCC13826_1227 144 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 157163956 Common rpiB ribose 5-phosphate isomerase B CCC13826_2228 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 157165566 Common yckK amino acid ABC transporter, periplasmic binding protein CCC13826_1696 56 None None None 157164555 Common - hypothetical protein CCC13826_1097 2 COG4929 COG4929, Uncharacterized membrane-anchored protein Function unknown 157165436 Common rpsT ribosomal protein S20 CCC13826_1806 162 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 157165688 Common - O-acetylhomoserine (thiol)-lyase CCC13826_1282 200 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 157164713 Common leuC 3-isopropylmalate dehydratase, large subunit CCC13826_2194 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 157163904 Common accB acetyl-CoA carboxylase, biotin carboxyl carrier protein CCC13826_2103 177 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 157165611 Common panD aspartate 1-decarboxylase CCC13826_1739 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 157164461 Common - ggdef domain protein CCC13826_0333 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 157165447 Common - methyl-accepting chemotaxis protein (MCP) signaling domain CCC13826_1234 124 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 157165034 Common - ribonucleoside-diphosphate reductase, alpha subunit CCC13826_1895 220 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 157164286 Common - addiction module toxin, Txe/YoeB CCC13826_1294 113 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 157163936 Pathogen - transmembrane transport protein CCC13826_0423 1 None None None 157164001 Common atpB ATP synthase F0, A subunit CCC13826_0159 195 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 157165498 Common hisD histidinol dehydrogenase CCC13826_2188 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 157165341 Pathogen - hypothetical protein CCC13826_0651 2 COG4575 ElaB, Uncharacterized conserved protein Function unknown 157165032 Common - lipid A export ATP-binding/permease protein MsbA CCC13826_0117 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 157165202 Common - integral membrane protein CCC13826_0772 5 None None None 157164950 Common - 50S ribosomal protein L18 CCC13826_0266 3 None None None 157165437 Pathogen - prophage protein gp49 CCC13826_1612 1 None None None 157165232 Common - hypothetical protein CCC13826_0810 18 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 157165082 Common - aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (Asp/Glu-ADT subunit B) CCC13826_1179 37 COG3455 COG3455, Uncharacterized protein conserved in bacteria Function unknown 157164812 Pathogen - ABC transporter ATP-binding protein uup CCC13826_0850 1 None None None 157164434 Pathogen - fumarate reductase flavoprotein subunit CCC13826_0977 1 None None None 157164624 Common - NC domain family CCC13826_1046 15 None None None 157164734 Common galU UTP-glucose-1-phosphate uridylyltransferase CCC13826_0429 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 157164230 Common - biotin-[acetyl-CoA-carboxylase] ligase CCC13826_0360 65 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 157164823 Pathogen atpD ATP synthase F1 sector beta subunit CCC13826_0137 1 None None None 157164725 Common - hypothetical protein CCC13826_0780 1 None None None 157164356 Common - hypothetical protein CCC13826_1883 5 None None None 157163922 Pathogen - hypothetical protein CCC13826_1690 1 None None None 157165505 Common lspA lipoprotein signal peptidase CCC13826_2148 6 None None None 157165239 Common - Rrf2 family protein (putative transcriptional regulator) CCC13826_2034 67 COG1959 COG1959, Predicted transcriptional regulator Transcription 157165133 Common - bacterial Cytochrome Ubiquinol Oxidase superfamily CCC13826_0906 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 157165748 Common - Cpp29 CCC13826_0450 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 157164484 Common fabG 3-oxoacyl-(acyl-carrier-protein) reductase CCC13826_0562 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 157165086 Pathogen - hypothetical protein CCC13826_0567 1 None None None 157165064 Pathogen - hypothetical protein CCC13826_1463 1 None None None 157163927 Common - methionyl-tRNA formyltransferase CCC13826_0782 23 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 157164239 Common - hypothetical protein CCC13826_1193 1 None None None 157165332 Pathogen - hypothetical protein CCC13826_0253 1 None None None 157164393 Pathogen - hypothetical protein CCC13826_0267 1 None None None 157164752 Common - putative nucleobase:cation symporter CCC13826_1180 5 None None None 157165751 Common - putative conserved hypothetical protein CCC13826_1742 83 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 157164414 Common - methyl-accepting chemotaxis protein CCC13826_1058 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 157165412 Common - ABC transport permease protein-involved in lipoprotein release CCC13826_0766 88 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 157164959 Common - putative periplasmic protein CCC13826_1045 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 157164995 Pathogen - hypothetical protein CCC13826_1986 1 None None None 157165339 Common - glutamine-binding periplasmic protein/glutamine transport system permease protein CCC13826_1924 182 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 157164892 Common - flavoCytochrome c heme subunit CCC13826_1830 5 None None None 157164128 Common - transporter, small conductance mechanosensitive ion channel (MscS) family CCC13826_0086 25 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 157164761 Common ftsI cell division protein CCC13826_1800 65 COG1971 COG1971, Predicted membrane protein Function unknown 157164583 Common rpsH ribosomal protein S8 CCC13826_1763 233 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 157165017 Common - acyl-CoA hydrolase CCC13826_1856 144 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 157165454 Common - amino acid carrier protein AlsT CCC13826_1997 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 157165770 Common - abc-type transporter, atpase component CCC13826_2202 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 157165312 Common - DedA family protein CCC13826_0529 11 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157164424 Common - peptidase, M48 family CCC13826_1711 129 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 157165424 Common - iron(III) dicitrate-binding protein CCC13826_0045 58 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 157165577 Common thiD phosphomethylpyrimidine kinase CCC13826_1843 21 COG4335 COG4335, DNA alkylation repair enzyme DNA replication, recombination, and repair 157165554 Common - hypothetical protein CCC13826_0770 1 None None None 157165674 Pathogen plsX fatty acid/phospholipid synthesis protein CCC13826_1209 1 None None None 157164515 Common hemC porphobilinogen deaminase CCC13826_1048 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 157165746 Common serS seryl-tRNA synthetase CCC13826_0773 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 157163945 Pathogen - hypothetical protein CCC13826_1301 1 None None None 157164659 Common - AAA ATPase, central region CCC13826_0165 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 157164914 Common - putative integral membrane protein CCC13826_1495 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 157164478 Pathogen - hypothetical protein CCC13826_1719 1 None None None 157165753 Pathogen - co-chaperone protein GrpE CCC13826_0303 1 COG1737 RpiR, Transcriptional regulators Transcription 157164622 Common - alpha-2-macroglobulin family N- region CCC13826_1253 69 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 157164052 Common cas crispr-associated protein Cas1 CCC13826_1425 86 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 157164279 Pathogen - transglutaminase family protein CCC13826_0907 1 None None None 157164835 Common - hypothetical protein CCC13826_0292 1 None None None 157164303 Pathogen - hypothetical protein CCC13826_0962 1 None None None 157165178 Common - NifU family protein CCC13826_0248 149 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 157164850 Common - DNA gyrase subunit A CCC13826_1076 30 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 157164065 Common flgB flagellar basal-body rod protein FlgB CCC13826_0058 68 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 157164322 Common csrA carbon storage regulator CCC13826_0062 12 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 157164031 Common - sodium:neurotransmitter symporter family CCC13826_1611 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 157165044 Common - protease htpx CCC13826_1039 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 157164715 Pathogen - hypothetical protein CCC13826_1205 1 None None None 157164119 Pathogen - hypothetical protein CCC13826_2290 1 None None None 157165061 Common typA GTP-binding protein TypA/BipA CCC13826_1124 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 157164033 Common - peptidase M50 CCC13826_1635 10 None None None 157164991 Common miaB tRNA-I(6)A37 thiotransferase enzyme MiaB CCC13826_0597 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 157164581 Common - phosphoribosylformylglycinamidine cyclo-ligase CCC13826_2111 65 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 157165319 Common - hypothetical protein CCC13826_2022 29 COG3236 COG3236, Uncharacterized protein conserved in bacteria Function unknown 157165592 Common aroQ 3-dehydroquinate dehydratase, type II CCC13826_0370 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 157164650 Common - 3-deoxy-D-manno-octulosonic-acid transferase CCC13826_1436 117 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 157164104 Common - two component transcriptional regulator, winged helix family CCC13826_0386 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157165468 Common serA phosphoglycerate dehydrogenase CCC13826_0489 56 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 157165051 Pathogen - hypothetical protein CCC13826_0673 1 None None None 157164463 Common thiD phosphomethylpyrimidine kinase CCC13826_0399 213 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 157163853 Common infA translation initiation factor IF-1 CCC13826_1755 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 157164723 Common - putative integral membrane protein CCC13826_1466 183 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 157164699 Common pyrG CTP synthase CCC13826_0908 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 157164615 Common - tetratricopeptide repeat domain protein CCC13826_0745 9 None None None 157163913 Common - rhomboid family protein CCC13826_0066 88 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 157165015 Pathogen - hypothetical protein CCC13826_1029 1 None None None 157164528 Common - hypothetical protein CCC13826_1870 117 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 157164447 Common - hypothetical protein CCC13826_1911 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 157165330 Common pyrE orotate phosphoribosyltransferase CCC13826_1866 104 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 157164807 Pathogen - hypothetical protein CCC13826_0643 1 None None None 157164664 Pathogen - hypothetical protein CCC13826_1852 1 None None None 157163991 Common - molybdenum cofactor biosynthesis protein A CCC13826_1396 139 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 157165337 Common - dynamin family protein CCC13826_0403 39 COG0486 ThdF, Predicted GTPase General function prediction only 157165761 Common - S-adenosylmethionine synthetase (Methionineadenosyltransferase; AdoMet synthetase; MAT) CCC13826_1787 114 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 157165737 Common rplU ribosomal protein L21 CCC13826_0997 169 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 157165214 Common - anthranilate synthase component 1 (Anthranilate synthasecomponent I) CCC13826_1602 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 157164080 Common - hypothetical protein CCC13826_0836 2 None None None 157164453 Common - hypothetical protein CCC13826_0982 169 COG0344 COG0344, Predicted membrane protein Function unknown 157164884 Common acpP acyl carrier protein CCC13826_0561 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 157165046 Common dnaG DNA primase CCC13826_0795 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 157165305 Common - putative conserved hypothetical protein CCC13826_1622 53 COG0759 COG0759, Uncharacterized conserved protein Function unknown 157165459 Common atpA ATP synthase F1, alpha subunit CCC13826_0915 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 157164669 Common murF UDP-MurNac-pentapeptide presynthetase CCC13826_1134 39 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 157164689 Pathogen - hypothetical protein CCC13826_2291 1 None None None 157165058 Common - putative lipoprotein CCC13826_1476 10 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 157163888 Common - trna (uracil-5-)-methyltransferase (trna(m-5-u54)-methyltransferase; rumt) CCC13826_1983 197 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 157164413 Pathogen - ATPase CCC13826_1091 2 None None None 157163975 Common rpmH ribosomal protein L34 CCC13826_2243 77 None None None 157165722 Common ispE 4-diphosphocytidyl-2C-methyl-D-erythritol kinase CCC13826_0061 41 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 157165776 Common - putative Carbon storage regulator homolog CCC13826_1793 167 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 157165166 Common - periplasmic binding protein CCC13826_1285 85 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 157164297 Common gmhA phosphoheptose isomerase CCC13826_0578 122 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 157164261 Common - PP-loop family protein CCC13826_0091 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 157164038 Common - heavy metal transport/detoxification protein CCC13826_0435 96 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 157165604 Common rplM ribosomal protein L13 CCC13826_0737 230 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 157165268 Common - S-adenosylmethionine:tRNA ribosyltransferase-isomerase (Queuosine biosynthesis protein QueA) CCC13826_0344 1 None None None 157164094 Common - UDP-N-acetylglucosamine 2-epimerase CCC13826_0521 153 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 157164924 Pathogen - putative periplasmic protein CCC13826_2242 1 None None None 157165359 Common ilvD dihydroxy-acid dehydratase CCC13826_0012 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 157164938 Common - zonular occludens toxin (Zot) family CCC13826_2276 2 COG4128 Zot, Zonula occludens toxin General function prediction only 157165250 Common - S-ribosylhomocysteine lyase (Autoinducer-2 productionprotein LuxS; AI-2 synthesis protein) CCC13826_2098 35 COG2107 COG2107, Predicted periplasmic solute-binding protein General function prediction only 157165536 Common - hypothetical protein CCC13826_2043 2 None None None 157164759 Common ackA acetate kinase CCC13826_0104 162 COG0282 ackA, Acetate kinase Energy production and conversion 157165514 Common - nitric oxide reductase large subunit CCC13826_0454 177 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157164010 Common - site-specific recombinase, phage integrase family protein CCC13826_0706 91 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 157165547 Pathogen - L-cystine-binding protein TcyA CCC13826_1698 1 None None None 157164268 Common ilvC ketol-acid reductoisomerase CCC13826_2003 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 157164019 Common - hypothetical protein CCC13826_2198 2 None None None 157164505 Pathogen - hypothetical protein CCC13826_0945 1 None None None 157163961 Common - ferric-uptake regulator CCC13826_2004 58 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 157165407 Common - 30S ribosomal protein S8 CCC13826_0269 26 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 157164791 Common trpS tryptophanyl-tRNA synthetase CCC13826_0775 241 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157165661 Pathogen - hypothetical protein CCC13826_0641 2 None None None 157165587 Pathogen - hypothetical protein CCC13826_2144 1 None None None 157165350 Common tmk thymidylate kinase CCC13826_1271 219 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 157165712 Common - putative polysaccharide deacetylase CCC13826_0920 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 157164857 Pathogen - two component transcriptional regulator, winged helix family CCC13826_0821 1 None None None 157164332 Common - hydrolase CCC13826_2107 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 157163875 Common - hypothetical protein CCC13826_1882 9 None None None 157164270 Common htrA serine protease CCC13826_1288 28 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 157165107 Common terC TerC protein CCC13826_2169 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 157165766 Common - chemotaxis protein CheV CCC13826_1579 183 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 157165400 Common - nitroreductase family protein CCC13826_2134 91 COG0778 NfnB, Nitroreductase Energy production and conversion 157164172 Common - flavodoxin CCC13826_1929 72 COG0716 FldA, Flavodoxins Energy production and conversion 157165237 Common - 3-phosphoshikimate 1-carboxyvinyltransferase CCC13826_0485 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 157164156 Common - hypothetical protein CCC13826_0037 4 None None None 157164246 Common - modification methylase HaeIII (Cytosine-specificmethyltransferase HaeIII; M.HaeIII) CCC13826_0819 116 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 157165285 Common flgC flagellar basal-body rod protein FlgC CCC13826_0057 123 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 157164077 Common hsdM type I restriction-modification system, M subunit CCC13826_1974 30 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 157164263 Pathogen - hypothetical protein CCC13826_2151 1 None None None 157164740 Common - outer membrane fibronectin-binding protein CCC13826_0739 166 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 157164749 Common - hypothetical protein CCC13826_0720 30 COG2836 COG2836, Uncharacterized conserved protein Function unknown 157165066 Common - hypothetical aminotransferase YfdZ CCC13826_1385 3 None None None 157165559 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase, YrbI family CCC13826_1990 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 157164498 Common valS valyl-tRNA synthetase CCC13826_1252 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157164965 Common - putative transport-associated CCC13826_2199 18 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 157164124 Common - thiamine monophosphate synthase/teni subfamily CCC13826_1279 27 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 157163881 Common thiF thiamine biosynthesis protein ThiF CCC13826_1276 149 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 157165150 Common grpE co-chaperone GrpE CCC13826_2045 230 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 157163998 Common rarD RarD protein CCC13826_0151 81 COG2962 RarD, Predicted permeases General function prediction only 157164110 Common - acetyltransferase CCC13826_0434 73 COG0579 COG0579, Predicted dehydrogenase General function prediction only 157165574 Common - hypothetical protein CCC13826_2160 86 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 157164843 Common cas crispr-associated protein Cas4 CCC13826_1423 34 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 157164403 Common - hypothetical protein CCC13826_1075 49 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 157163866 Common rplT ribosomal protein L20 CCC13826_1840 215 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 157165192 Common - Na+/H+ antiporter family protein CCC13826_1982 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 157164048 Pathogen - hypothetical protein CCC13826_1198 1 None None None 157164947 Pathogen - hypothetical protein CCC13826_2215 1 None None None 157165367 Pathogen - hypothetical protein CCC13826_1877 2 None None None 157165299 Common clpX ATP-dependent Clp protease, ATP-binding subunit ClpX CCC13826_2124 222 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 157164688 Common - putative helix-turn-helix containsing protein CCC13826_0345 11 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 157165614 Common pheS phenylalanyl-tRNA synthetase, alpha subunit CCC13826_1563 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 157165291 Pathogen - hypothetical protein CCC13826_1303 1 None None None 157165310 Common - tRNA-I(6)A37 thiotransferase enzyme MiaB CCC13826_1587 27 COG0795 COG0795, Predicted permeases General function prediction only 157163891 Common - Two-component sensor kinase CzcS CCC13826_1741 7 None None None 157164446 Pathogen - hypothetical protein CCC13826_2265 1 None None None 157164319 Common tsf translation elongation factor Ts CCC13826_0550 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 157164196 Common - Sel1 repeat family CCC13826_0589 82 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 157165593 Common - UDP-N-acetylglucosamine 2-epimerase CCC13826_2302 67 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 157164090 Common gltA citrate (Si)-synthase CCC13826_2287 194 COG0372 GltA, Citrate synthase Energy production and conversion 157165252 Pathogen - hypothetical protein CCC13826_1748 1 None None None 157164132 Common - putative periplasmic protein CCC13826_0685 3 None None None 157165484 Common lys1 saccharopine dehydrogenase CCC13826_0747 52 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 157164139 Common - Sel1 repeat family CCC13826_2180 91 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 157164709 Common omp peptidoglycan associated lipoprotein CCC13826_0131 183 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 157165373 Common - outer membrane protein transport protein (ompp1/fadl/todx) CCC13826_1772 69 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 157165050 Pathogen - hypothetical protein CCC13826_1835 1 None None None 157165187 Common rplS ribosomal protein L19 CCC13826_1429 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 157164753 Pathogen - hypothetical protein CCC13826_1685 1 None None None 157164954 Pathogen - NADP-dependent malic enzyme (nadp-me) CCC13826_1940 1 None None None 157165039 Common nusG transcription termination/antitermination factor NusG CCC13826_0169 214 COG0250 NusG, Transcription antiterminator Transcription 157163879 Pathogen - hypothetical protein CCC13826_0199 1 None None None 157165550 Common - glyoxalase II CCC13826_1985 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 157165267 Common - hypothetical protein CCC13826_1226 2 None None None 157165695 Common - para protein CCC13826_1600 28 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 157165384 Common - ABC-2 type transporter superfamily CCC13826_1721 16 None None None 157165671 Common rpmE ribosomal protein L31 CCC13826_1150 184 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 157165430 Common thrS threonyl-tRNA synthetase CCC13826_1819 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157165653 Common - hypothetical protein CCC13826_1677 5 None None None 157164468 Common - polysulphide reductase, NrfD CCC13826_1874 26 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 157165132 Pathogen - multifunctional CCA protein CCC13826_1816 1 None None None 157165008 Common tktA transketolase A CCC13826_0241 200 COG0281 SfcA, Malic enzyme Energy production and conversion 157164219 Pathogen - endonuclease/exonuclease/phosphatase CCC13826_1814 1 None None None 157164148 Common rnhB ribonuclease HII CCC13826_0342 236 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 157164594 Common glyQ glycyl-tRNA synthetase, alpha subunit CCC13826_1439 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 157165749 Pathogen - hypothetical protein CCC13826_0192 1 None None None 157165549 Common - hypothetical protein CCC13826_1127 7 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 157165234 Pathogen - hypothetical protein CCC13826_2029 1 None None None 157165030 Common - MTA/SAH nucleosidase CCC13826_0092 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 157165326 Common sodC copper/zinc superoxide dismutase CCC13826_0161 84 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 157165472 Common - transferase hexapeptide repeat CCC13826_1533 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 157165040 Common acrB acriflavine resistance protein CCC13826_0892 126 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 157165280 Common - putative conserved hypothetical protein CCC13826_2110 42 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 157165154 Common thiH thiazole biosynthesis protein ThiH CCC13826_1278 55 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 157165445 Common dapA dihydrodipicolinate synthase CCC13826_0120 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 157165646 Pathogen - isoaspartyl dipeptidase CCC13826_1637 1 None None None 157165375 Common - hypothetical protein CCC13826_1703 8 None None None 157165439 Common - thioesterase family protein CCC13826_1618 112 COG0824 FcbC, Predicted thioesterase General function prediction only 157164192 Common - trap dicarboxylate transporter, dctm subunit CCC13826_1507 126 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 157164160 Common - putative hemagglutinin/hemolysin-related protein CCC13826_2126 17 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 157164358 Common - hydrogenase-4 component C CCC13826_2309 7 None None None 157164679 Pathogen - hypothetical protein CCC13826_1447 1 None None None 157164258 Common iadA beta-aspartyl peptidase CCC13826_0552 36 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 157163939 Common - putative ABC transporter, ATP-binding protein CCC13826_2120 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 157165201 Common modB molybdate ABC transporter, permease protein CCC13826_2282 214 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 157164436 Pathogen rplT 50S ribosomal protein L20 CCC13826_2115 1 None None None 157164537 Common - hypothetical protein CCC13826_1610 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 157165631 Common - hypothetical protein CCC13826_1802 4 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 157165570 Common - hypothetical protein CCC13826_0765 17 COG4393 COG4393, Predicted membrane protein Function unknown 157164608 Pathogen - hypothetical protein CCC13826_0812 1 None None None 157164497 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha region CCC13826_1701 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 157164224 Common - hypothetical protein CCC13826_2063 3 None None None 157164169 Common - hypothetical protein CCC13826_0852 8 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 157164832 Pathogen - hypothetical protein CCC13826_0856 1 None None None 157164406 Pathogen - hypothetical protein CCC13826_2207 1 None None None 157164518 Common - hypothetical protein CCC13826_0582 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 157164271 Common - peptidase family M41 CCC13826_1351 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 157165171 Common - glycosyl transferase, group 1 family protein CCC13826_0478 146 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157165709 Pathogen - hypothetical protein CCC13826_1174 2 None None None 157164929 Common patB aminotransferase, class II CCC13826_0327 223 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 157163957 Common dapE succinyl-diaminopimelate desuccinylase CCC13826_0246 212 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 157165128 Common kdsB 3-deoxy-D-manno-octulosonate cytidylyltransferase CCC13826_2053 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 157164645 Common - 4Fe-4S binding domain protein CCC13826_1915 148 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 157165700 Common - permease CCC13826_0752 8 None None None 157164878 Common - DNA polymerase III, delta subunit superfamily CCC13826_1999 7 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 157165126 Pathogen - hypothetical protein CCC13826_2277 1 None None None 157165410 Common dnaJ chaperone protein DnaJ CCC13826_0965 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 157163909 Common glyA serine hydroxymethyltransferase CCC13826_0226 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 157164564 Pathogen - hypothetical protein CCC13826_0186 1 None None None 157165660 Common groS chaperonin GroS CCC13826_0668 137 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 157164585 Common - DegT/DnrJ/EryC1/StrS aminotransferase family CCC13826_2305 190 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 157164109 Common - trap dicarboxylate transporter- dctm subunit CCC13826_0331 135 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 157165331 Common - protein CysQ CCC13826_2286 173 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 157163982 Common - putative integral membrane protein CCC13826_0537 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 157165144 Common - arylsulfate sulfotransferase CCC13826_0153 1 None None None 157164630 Common - hypothetical protein CCC13826_0539 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 157164388 Common - putative chemotaxis protein MotB CCC13826_2072 34 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 157164544 Common - response regulatory protein CCC13826_0768 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 157164772 Common - sensor histidine kinase CCC13826_1286 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 157164657 Common - cytosol aminopeptidase CCC13826_0528 41 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 157165417 Common - malate:quinone oxidoreductase (Malate dehydrogenase[acceptor]; MQO) CCC13826_0986 218 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 157165669 Common lpxB lipid-A-disaccharide synthase CCC13826_1576 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 157164335 Common - transmembrane transport protein CCC13826_0424 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 157165011 Common lspA signal peptidase II CCC13826_1808 119 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 157164475 Common - hypothetical protein CCC13826_0125 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 157165223 Common tyrA prephenate dehydrogenase CCC13826_1343 3 None None None 157164470 Pathogen - two-component regulator CCC13826_1203 1 None None None 157164557 Common pepQ prolidase (Xaa-Pro dipeptidase; PepQ) CCC13826_0804 54 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 157165779 Common - putative integral membrane protein CCC13826_1486 7 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 157164123 Common - phosphatidylglycerophosphatase A CCC13826_0387 28 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 157163965 Common purD phosphoribosylamine--glycine ligase CCC13826_0492 232 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 157163902 Common truB tRNA pseudouridine synthase B CCC13826_0063 240 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 157164014 Common - hypothetical protein CCC13826_0646 147 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 157164066 Common - plasminogen-binding protein PgbB CCC13826_0219 7 None None None 157164863 Common - hypothetical protein CCC13826_1619 6 None None None 157165755 Pathogen - putative surface protein CCC13826_0932 2 None None None 157165509 Common rpoA DNA-directed RNA polymerase, alpha subunit CCC13826_1751 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 157164276 Common acpS holo-(acyl-carrier-protein) synthase CCC13826_1319 110 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 157165277 Common selB selenocysteine-specific translation elongation factor CCC13826_0756 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 157164732 Common fliG flagellar motor switch protein FliG CCC13826_1592 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 157164637 Common - putative endonuclease CCC13826_1335 11 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 157164920 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase CCC13826_0378 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 157164700 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CCC13826_0368 184 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 157164320 Common lysA diaminopimelate decarboxylase CCC13826_1588 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 157165523 Common - putative D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain CCC13826_1648 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 157164827 Common - argininosuccinate synthase (Citrulline--aspartateligase) CCC13826_0600 75 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 157165026 Common - response regulator CCC13826_1849 90 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 157164118 Common - flagellar basal-body rod protein CCC13826_2185 124 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 157165504 Common - hypothetical protein CCC13826_2030 1 COG0628 PerM, Predicted permease General function prediction only 157164368 Pathogen - putative L-arabinose ABC transporter CCC13826_2156 1 None None None 157164935 Common - riboflavin biosynthesis protein ribAB CCC13826_1413 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 157164040 Common - glutamate racemase 2 CCC13826_0084 20 COG2863 COG2863, Cytochrome c553 Energy production and conversion 157164704 Common - glycosyl transferase, group 1 CCC13826_1512 156 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 157163920 Common pgsA phosphatidylglycerophosphate synthase CCC13826_1147 5 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 157164046 Common - hypothetical protein CCC13826_1264 4 None None None 157165264 Common - formate dehydrogenase iron-sulfur subunit CCC13826_0762 172 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 157165719 Common - hypothetical protein CCC13826_0254 1 None None None 157165585 Common radA DNA repair protein RadA CCC13826_1314 204 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 157165533 Pathogen - putative ribosomal RNA adenine dimethylase CCC13826_0042 1 None None None 157164329 Pathogen - hypothetical protein CCC13826_1049 1 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 157165360 Pathogen - hypothetical protein CCC13826_0108 1 None None None 157164677 Common - hypothetical protein CCC13826_0761 180 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 157164571 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase CCC13826_0138 178 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 157164151 Common modD ModD protein CCC13826_1392 199 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 157165425 Common speA arginine decarboxylase CCC13826_1273 134 COG1166 SpeA, Arginine decarboxylase (spermidine biosynthesis) Amino acid transport and metabolism 157164162 Common - sodium- and chloride-dependent transporter CCC13826_0422 35 COG1715 Mrr, Restriction endonuclease Defense mechanisms 157164975 Common cdsA phosphatidate cytidylyltransferase CCC13826_0421 214 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 157165219 Pathogen pyk pyruvate kinase CCC13826_1323 1 None None None 157165582 Common hslU heat shock protein HslVU, ATPase subunit HslU CCC13826_1222 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 157165481 Common norM MatE efflux family protein CCC13826_2166 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 157164775 Common thiD phosphomethylpyrimidine kinase CCC13826_0361 221 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 157164480 Common - hydrogenase-4 component I CCC13826_0713 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 157164994 Common - hypothetical protein CCC13826_1432 9 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 157164240 Pathogen - putative phosphonate uptake transporter CCC13826_1101 1 None None None 157164748 Common - methyl-accepting chemotaxis protein CCC13826_1521 92 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 157165216 Common trpE anthranilate synthase, component I CCC13826_0523 17 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157165710 Common lnt apolipoprotein N-acyltransferase CCC13826_0069 96 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 157164721 Common - general glycosylation pathway protein CCC13826_1006 132 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 157164844 Common - 50S ribosomal protein L5 (BL6) CCC13826_1765 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 157165108 Common - ATP synthase subunit B CCC13826_0912 31 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 157165352 Pathogen - hypothetical protein CCC13826_1164 1 None None None 157165553 Common - ExbB\TolQ family transport protein CCC13826_0919 140 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 157165539 Common thiC thiamine biosynthesis protein ThiC CCC13826_1468 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 157164408 Pathogen - hypothetical protein CCC13826_0683 1 COG1422 COG1422, Predicted membrane protein Function unknown 157165369 Common ffh signal recognition particle protein CCC13826_1434 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 157163950 Common - antioxidant, AhpC/TSA family CCC13826_2112 227 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 157163884 Common - hypothetical protein CCC13826_0595 3 None None None 157165101 Common - nlpa lipoprotein CCC13826_1247 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 157164155 Common - putative Mg chelatase homolog CCC13826_1784 190 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 157163872 Pathogen - hypothetical protein CCC13826_2042 1 None None None 157164133 Common truA tRNA pseudouridine synthase A CCC13826_0699 227 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 157164075 Common rfaC lipopolysaccharide heptosyltransferase I CCC13826_0470 81 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 157165297 Common - peptidase, M50 family CCC13826_0830 80 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 157164941 Common rpsI ribosomal protein S9 CCC13826_0738 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 157165625 Common argF ornithine carbamoyltransferase CCC13826_0885 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 157164590 Common - hypothetical protein CCC13826_1480 12 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 157164482 Common - Hsp12 variant C CCC13826_0647 15 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 157165442 Common nhaC Na+/H+ antiporter NhaC CCC13826_1636 102 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 157164968 Common pcrA ATP-dependent DNA helicase PcrA CCC13826_1791 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 157165572 Common - ATP/GTP hydrolase CCC13826_0581 209 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 157165231 Common - hypothetical protein CCC13826_0742 1 None None None 157165190 Common - nitrogenase cofactor biosynthesis protein NifB CCC13826_1743 76 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 157164401 Common rpmC ribosomal protein L29 CCC13826_1769 15 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 157164266 Common recA protein RecA CCC13826_2094 237 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 157164551 Pathogen ompR response regulator CCC13826_0026 2 None None None 157165093 Common tig trigger factor CCC13826_1780 210 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 157164625 Pathogen - hypothetical protein CCC13826_1968 1 None None None 157165633 Common - saccharopine dehydrogenase CCC13826_0697 119 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 157164314 Common - response regulator receiver domain protein CCC13826_0005 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157164054 Common fixN cytochrome c oxidase, heme b and copper-binding subunit, membrane-bound CCC13826_1469 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 157163970 Common - Sel1 repeat family CCC13826_1720 11 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 157165643 Common aroB 3-dehydroquinate synthase CCC13826_0087 207 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 157165099 Common - methionine import ATP-binding protein MetN CCC13826_1250 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 157164503 Pathogen - outer membrane lipoprotein MapA CCC13826_0858 1 None None None 157165728 Common - putative flagellar hook-associated protein 2 CCC13826_1258 123 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 157165021 Common trx thioredoxin CCC13826_1142 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 157165601 Common - transcription termination factor NusA CCC13826_1589 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 157164516 Pathogen - lysyl-tRNA synthetase (Lysine--tRNA ligase; LysRS) CCC13826_1691 1 None None None 157164489 Pathogen - hypothetical protein CCC13826_1527 1 None None None 157164379 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase CCC13826_1594 211 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 157165659 Common - hypothetical protein CCC13826_0935 7 None None None 157163977 Common - C4-dicarboxylate-binding periplasmic protein CCC13826_0329 115 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 157164814 Pathogen - putative putative periplasmic protein CCC13826_1047 1 None None None 157164684 Pathogen - hypothetical protein CCC13826_0184 1 None None None 157164454 Common - hypothetical protein CCC13826_0263 1 None None None 157164374 Pathogen - hypothetical protein CCC13826_2241 1 None None None 157164774 Common - putative lipopolysaccharide heptosyltransferase III CCC13826_0473 86 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 157165079 Common glmU UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase CCC13826_0692 223 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 157164902 Pathogen - SNF7 family protein CCC13826_1204 1 None None None 157164953 Common - NAD(FAD)-utilizing dehydrogenase CCC13826_0702 83 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 157165542 Pathogen rplQ 50S ribosomal protein L17 CCC13826_0256 1 None None None 157164987 Pathogen - DNA-directed RNA polymerase alpha chain CCC13826_0257 1 None None None 157165519 Common - DnaJ domain protein CCC13826_0703 7 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 157163993 Common - flagellar assembly protein CCC13826_1593 37 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 157165173 Common - ATPase, AAA family protein CCC13826_1825 248 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 157165317 Common hisS histidyl-tRNA synthetase CCC13826_1272 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157164346 Common ribH 6,7-dimethyl-8-ribityllumazine synthase CCC13826_0783 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 157164097 Pathogen - diguanylate cyclase/phosphodiesterase CCC13826_1934 1 None None None 157165388 Common - carbamoyl-phosphate synthase large chain (Carbamoyl-phosphate synthetase ammonia chain) CCC13826_1487 6 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 157164809 Common - septicolysin CCC13826_0326 15 None None None 157165115 Common - peptide ABC transporter, periplasmic peptide-binding protein CCC13826_1887 166 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 157164107 Common fliN flagellar motor switch protein FliN CCC13826_0975 119 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 157165303 Pathogen - hypothetical protein CCC13826_1347 1 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 157165067 Pathogen - hypothetical protein CCC13826_2065 1 None None None 157165301 Common dcd deoxycytidine triphosphate deaminase CCC13826_2308 154 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 157165768 Common - glycosysltransferase CCC13826_1007 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 157165349 Common yegQ protease YegQ CCC13826_1021 124 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 157164441 Common - aminotransferase CCC13826_0949 4 None None None 157165496 Common serC phosphoserine aminotransferase CCC13826_1599 117 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 157164526 Common - ABC transporter ATP-binding protein YojI CCC13826_1655 249 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 157163937 Common dcuA anaerobic C4-dicarboxylate transporter DcuA CCC13826_1224 5 None None None 157165287 Common selA L-seryl-tRNA selenium transferase CCC13826_0755 65 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 157164801 Common rplP ribosomal protein L16 CCC13826_1770 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 157164967 Common hisF imidazoleglycerol phosphate synthase, cyclase subunit CCC13826_1890 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 157164307 Pathogen - hypothetical protein CCC13826_0311 1 None None None 157163868 Common rplX ribosomal protein L24 CCC13826_1766 206 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 157164787 Common alr alanine racemase CCC13826_0875 197 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 157164300 Pathogen - hypothetical protein CCC13826_0961 1 None None None 157164487 Common pepD dipeptidase CCC13826_2117 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 157165226 Pathogen - hypothetical protein CCC13826_1299 1 None None None 157165199 Pathogen - hypothetical protein CCC13826_0946 1 None None None 157164004 Common accD acetyl-CoA carboxylase, carboxyl transferase, beta subunit CCC13826_0941 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 157164021 Common - SCO1/SenC family protein CCC13826_0870 97 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 157164425 Common - hypothetical protein CCC13826_0598 7 None None None 157164057 Common - bifunctional protein HldE CCC13826_1567 224 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 157164891 Common - aliphatic sulfonate ABC transporter permease protein CCC13826_0252 42 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 157165018 Common hemE uroporphyrinogen decarboxylase CCC13826_1237 34 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 157165308 Common hypA hydrogenase nickel insertion protein HypA CCC13826_1092 94 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 157164036 Pathogen - hypothetical protein CCC13826_0033 4 None None None 157164294 Common - MadN protein CCC13826_0890 121 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 157165686 Common - OmpA family protein CCC13826_0690 146 COG1360 MotB, Flagellar motor protein Cell motility and secretion 157164828 Pathogen - hypothetical protein CCC13826_1169 1 None None None 157164640 Common - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase CCC13826_0886 4 None None None 157164714 Common - cell division protein, FtsW/RodA/SpoVE family CCC13826_1244 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 157165591 Common - D12 class N6 adenine-specific DNA methyltransferase superfamily CCC13826_1858 15 COG3392 COG3392, Adenine-specific DNA methylase DNA replication, recombination, and repair 157163854 Pathogen - hypothetical protein CCC13826_1135 1 None None None 157164617 Common - zonular occludens toxin (Zot) family CCC13826_2075 2 COG4128 Zot, Zonula occludens toxin General function prediction only 157165628 Common - putative cytochrome B(N-)/b6/PetB subfamily CCC13826_1920 145 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 157165392 Common - type I restriction enzyme EcoR124II R protein (R.EcoR124II) CCC13826_1410 135 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 157164647 Common atpD ATP synthase F1, beta subunit CCC13826_0917 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 157163861 Common - hypothetical protein CCC13826_1790 167 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 157165399 Common - thioredoxin reductase (trxr) CCC13826_1380 133 COG2860 COG2860, Predicted membrane protein Function unknown 157164415 Common prmA ribosomal protein L11 methyltransferase CCC13826_0442 173 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 157164782 Common - transcriptional activator protein CopR CCC13826_1740 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 157165340 Common - PepSY-associated TM helix family CCC13826_0298 19 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 157164855 Common - acetyltransferase, gnat family CCC13826_1515 19 COG0456 RimI, Acetyltransferases General function prediction only 157164181 Common - peptidase propeptide and ypeb domain protein CCC13826_1967 11 COG3212 COG3212, Predicted membrane protein Function unknown 157165598 Common - branched-chain amino acid transport protein CCC13826_0028 14 COG1687 AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) Amino acid transport and metabolism 157164337 Common - putative orphan protein CCC13826_2121 66 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 157165243 Common - S-layer-RTX protein CCC13826_1838 24 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 157164983 Common - putative phage integrase CCC13826_0013 137 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 157165443 Common - hypothetical protein CCC13826_0065 7 None None None 157165432 Common - hypothetical protein CCC13826_1952 1 None None None 157165638 Common - glycyl-tRNA synthetase alpha chain (Glycine--tRNA ligasealpha chain; GlyRS) CCC13826_1017 57 COG3189 COG3189, Uncharacterized conserved protein Function unknown 157164560 Common - M23 peptidase domain protein CCC13826_1331 191 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 157164428 Common - NH(3)-dependent NAD(+) synthetase CCC13826_0300 2 COG3668 ParE, Plasmid stabilization system protein General function prediction only 157164596 Common - transporter gate domain protein CCC13826_1336 11 COG0700 SpmB, Uncharacterized membrane protein Function unknown 157163934 Common - tetrahydrofolate dehydrogenase/cyclohydrolase, NAD(P)-binding domain protein CCC13826_0832 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 157164587 Pathogen - hypothetical protein CCC13826_0409 1 None None None 157165134 Common - 2-acylglycerophosphoethanolamine acyltransferase CCC13826_2319 81 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 157165137 Pathogen - hypothetical protein CCC13826_1315 1 None None None 157164796 Pathogen - Cpp29 CCC13826_1531 1 None None None 157164034 Common pyrH uridylate kinase CCC13826_0502 229 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 157164430 Common - putative domain of unknown function CCC13826_0381 101 COG0628 PerM, Predicted permease General function prediction only 157164686 Common - hypothetical protein CCC13826_2187 65 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 157164569 Common - ATP phosphoribosyltransferase (ATP-PRTase; ATP-PRT) CCC13826_0608 32 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 157165255 Common - hypothetical protein CCC13826_1994 2 None None None 157164093 Common modA putative molybdenum ABC transporter, solute-binding protein CCC13826_1746 188 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 157163870 Common - L-cystine permease protein TcyB CCC13826_1699 2 None None None 157165772 Common - hypothetical protein CCC13826_1014 25 COG2862 COG2862, Predicted membrane protein Function unknown 157164853 Pathogen - hypothetical protein CCC13826_1339 1 None None None 157165206 Common - putative lipoprotein CCC13826_1916 84 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 157163897 Common - hypothetical protein CCC13826_2036 8 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 157164896 Common - P-protein CCC13826_0509 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 157164190 Common - putative aminotransferase CCC13826_0214 211 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 157164756 Common walN WalN protein CCC13826_1217 116 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 157164310 Common - cytochrome C assembly protein CCC13826_1461 82 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 157164397 Pathogen - hypothetical protein CCC13826_1749 1 None None None 157165083 Common rho transcription termination factor Rho CCC13826_0605 215 COG1158 Rho, Transcription termination factor Transcription 157165546 Pathogen - hypothetical protein CCC13826_1950 1 None None None 157165693 Pathogen - hypothetical protein CCC13826_1560 1 None None None 157165678 Common - hypothetical protein CCC13826_1441 4 None None None 157165057 Common - hypothetical protein CCC13826_0237 9 COG1427 COG1427, Predicted periplasmic solute-binding protein General function prediction only 157164176 Common - hypothetical protein CCC13826_0837 45 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 157164112 Common - preprotein translocase, YajC subunit CCC13826_1785 213 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 157164060 Common - hypothetical RNA pseudouridine synthase CCC13826_2281 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 157164299 Common - hypothetical protein CCC13826_1061 2 None None None 157164146 Pathogen - putative periplasmic protein CCC13826_1938 1 None None None 157164421 Common bcp bacterioferritin comigratory protein Bcp CCC13826_1891 7 None None None 157165069 Common - glycyl-tRNA synthetase beta chain (Glycine--tRNA ligasebeta chain; GlyRS) CCC13826_1812 235 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 157165293 Pathogen - hypothetical protein CCC13826_0296 2 None None None 157164130 Common - hypothetical protein CCC13826_1325 214 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 157165195 Common - GTP cyclohydrolase I (GTP-CH-I) CCC13826_0284 87 COG0824 FcbC, Predicted thioesterase General function prediction only 157164970 Common - hypothetical protein CCC13826_1483 86 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 157165289 Common - DNA gyrase subunit B CCC13826_2105 2 None None None 157164083 Common - phosphatase, Ppx/GppA family CCC13826_0602 4 None None None 157164234 Common folE GTP cyclohydrolase I CCC13826_1778 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 157165452 Common - hypothetical protein CCC13826_1908 3 None None None 157164512 Common - 50S ribosomal protein L24 (BL23; 12 kDa DNA-binding protein; HPB12) CCC13826_0272 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 157163916 Common - hypothetical protein CCC13826_0015 72 None None None 157165077 Common - phosphomethylpyrimidine kinase CCC13826_1956 51 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 157165458 Common - NhaD CCC13826_0476 97 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 157164251 Common - holo-[acyl-carrier-protein] synthase CCC13826_2069 161 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 157165370 Pathogen - hypothetical protein CCC13826_1118 1 None None None 157165377 Common - molybdopterin-guanine dinucleotide biosynthesis protein MobB CCC13826_0465 32 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 157164411 Common - hypothetical protein CCC13826_0735 29 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 157164643 Common - transporter, dme family CCC13826_1988 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 157164166 Common - formate/nitrite transporter CCC13826_0716 82 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 157164448 Pathogen - hypothetical protein CCC13826_1139 1 None None None 157165552 Common - hypothetical protein CCC13826_0016 17 None None None 157165742 Common - prokaryotic N- methylation motif domain protein CCC13826_1110 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 157164352 Common - sodium:neurotransmitter symporter family protein CCC13826_1505 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 157165013 Common - glutathionylspermidine synthase family protein CCC13826_2272 4 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 157164390 Common flhA flagellar biosynthesis protein FlhA CCC13826_2035 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 157164558 Common - DnaJ domain protein CCC13826_1065 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 157164290 Common nspC carboxynorspermidine decarboxylase CCC13826_2141 62 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 157165225 Common trmA tRNA (uracil-5-)-methyltransferase CCC13826_1404 172 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 157165116 Pathogen - hypothetical protein CCC13826_1936 1 None None None 157164361 Common psd phosphatidylserine decarboxylase CCC13826_1554 87 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 157164330 Common - ferredoxin-type protein, NapH/MauN family CCC13826_1723 83 COG0348 NapH, Polyferredoxin Energy production and conversion 157165328 Common - type II secretion system protein CCC13826_0587 5 None None None 157164553 Common dnaK chaperone protein DnaK CCC13826_2046 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 157164137 Common - ribosomal protein S10p/S20e CCC13826_2327 246 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 157163963 Common - transcriptional regulator superfamily CCC13826_0848 36 COG1959 COG1959, Predicted transcriptional regulator Transcription 157165006 Common - Ham1 family CCC13826_0746 231 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 157164546 Pathogen - hypothetical protein CCC13826_1397 1 None None None 157164354 Common - hypothetical protein CCC13826_0160 133 COG0730 COG0730, Predicted permeases General function prediction only 157165641 Pathogen - hypothetical protein CCC13826_0900 1 None None None 157165666 Pathogen nrdD oxygen-sensitive ribonucleoside-triphosphate reductase CCC13826_2294 1 None None None 157165156 Common - thiol peroxidase (Scavengase P20) CCC13826_0323 91 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 157163980 Common moaA molybdenum cofactor biosynthesis protein A CCC13826_1156 197 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 157165627 Common - hypothetical protein CCC13826_1471 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 157163952 Common - ribosomal protein L25, Ctc-form CCC13826_1585 145 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 157164522 Pathogen - hypothetical protein CCC13826_0538 1 None None None 157164868 Common - endonuclease III CCC13826_1775 53 COG4637 COG4637, Predicted ATPase General function prediction only 157164194 Pathogen - formate dehydrogenase, cytochrome B subunit CCC13826_1864 1 None None None 157164922 Pathogen - hypothetical protein CCC13826_1053 2 None None None 157164937 Common - carbamoyl-phosphate synthase large chain (Carbamoyl-phosphate synthetase ammonia chain) CCC13826_1876 94 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 157165321 Common secE preprotein translocase, SecE subunit CCC13826_0168 2 None None None 157164861 Common ccoG cytochrome c oxidase accessory protein CcoG CCC13826_1642 79 COG0348 NapH, Polyferredoxin Energy production and conversion 157165028 Common - RND transporter, Hydrophobe/Amphiphile Efflux-1 (HAE1) and Heavy Metal Efflux (HME) families, permease protein CCC13826_0686 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 157165757 Common - putative hydrolase, nudix family CCC13826_1333 21 None None None 157164044 Common - 4Fe-4S binding domain protein CCC13826_1873 161 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 157164492 Pathogen - hypothetical protein CCC13826_0054 1 None None None 157165164 Common - general glycosylation pathway protein CCC13826_0449 89 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 157165421 Common - processing protease CCC13826_1529 165 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 157164702 Common - twin-arginine translocation protein TatA/E CCC13826_1536 14 None None None 157165502 Common rpmI ribosomal protein L35 CCC13826_1839 128 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 157164252 Common dnaQ DNA polymerase III epsilon subunit CCC13826_2047 208 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 157164916 Common - hypothetical protein CCC13826_0055 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 157165616 Pathogen - hypothetical protein CCC13826_1519 1 None None None 157163959 Common ksgA dimethyladenosine transferase CCC13826_1888 246 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 157164364 Common - hypothetical protein CCC13826_1460 3 COG2863 COG2863, Cytochrome c553 Energy production and conversion 157164786 Pathogen - hypothetical protein CCC13826_1260 1 None None None 157164944 Common - sigma 54 modulation protein/ribosomal protein S30EA CCC13826_1737 12 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 157163987 Common dapF diaminopimelate epimerase CCC13826_1841 182 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 157164029 Common - protease DO CCC13826_1064 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 157165342 Common - hypothetical protein CCC13826_1022 4 None None None 157164203 Common rpsM ribosomal protein S13p/S18e CCC13826_1754 231 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 157163900 Common rpoN RNA polymerase sigma-54 factor CCC13826_1240 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 157165124 Common accA acetyl-CoA carboxylase, carboxyl transferase, alpha subunit CCC13826_0559 178 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 157165149 Common - putative Cytochrome c-type haem-binding periplasmic protein CCC13826_0126 10 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 157165575 Common - peptidase, M48 family CCC13826_0879 189 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 157164069 Pathogen - hypothetical protein CCC13826_0811 1 None None None 157165561 Common - tonB-dependent receptor domain protein CCC13826_1289 95 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 157164739 Common - His Kinase A CCC13826_0004 77 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 157164340 Common - pTet43 CCC13826_2027 4 None None None 157165733 Common rpsO ribosomal protein S15 CCC13826_2033 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 157163925 Common - type III restriction enzyme, res subunit family CCC13826_1530 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 157164214 Common - addiction module antitoxin, RelB/DinJ family CCC13826_1068 12 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 157164220 Common - putative ribosomal protein L10 CCC13826_0172 210 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 157164226 Common - fumarate reductase respiratory complex, transmembrane subunit CCC13826_0426 10 None None None 157164535 Common - TRAP transporter, DctQ-like membrane protein CCC13826_0330 76 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 157164998 Common - putative CoA-substrate-specific enzyme activase, putative CCC13826_1133 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 157165004 Common - hypothetical protein CCC13826_0818 2 None None None 157165703 Common pcm protein-L-isoaspartate O-methyltransferase CCC13826_0733 165 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 157164466 Common - large-conductance mechanosensitive channel CCC13826_0469 32 COG3298 COG3298, Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA replication, recombination, and repair 157165142 Common - nucleotide sugar dehydrogenase subfamily CCC13826_0461 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 157164381 Common pepF oligoendopeptidase F CCC13826_1789 178 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 157164573 Common - 50S ribosomal protein L19 CCC13826_1960 17 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 157164249 Common - ABC transporter ATP-binding protein YojI CCC13826_1100 92 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 157164887 Common nifS cysteine desulfurase, NifS family CCC13826_1163 240 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 157164876 Common fliQ flagellar biosynthetic protein FliQ CCC13826_2097 55 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 157163877 Common rplQ ribosomal protein L17 CCC13826_1750 215 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 157164264 Common - hypothetical protein CCC13826_1848 11 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 157164501 Common - anaerobic C4-dicarboxylate transporter DcuA CCC13826_0825 135 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 157164012 Common - 2-cys peroxiredoxin BAS1, (Thiol-specific antioxidant protein) CCC13826_0985 222 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 157163979 Common - phosphoglucosamine mutase CCC13826_2149 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 157164312 Common - putative endonuclease/exonuclease/phosphatase CCC13826_0041 19 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 157165169 Common frp NAD(P)H-flavin oxidoreductase CCC13826_1869 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157164372 Common - hypothetical protein CCC13826_0047 7 COG2183 Tex, Transcriptional accessory protein Transcription 157164359 Common lgt prolipoprotein diacylglyceryl transferase CCC13826_0427 208 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 157165334 Pathogen - hypothetical protein CCC13826_0289 1 None None None 157165657 Common flgB flagellar basal-body rod protein CCC13826_1797 30 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 157164894 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase CCC13826_0680 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 157165272 Common - mate efflux family protein CCC13826_1132 91 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 157163972 Common nusB transcription antitermination factor NusB CCC13826_0784 153 COG0781 NusB, Transcription termination factor Transcription 157165494 Common panC pantoate--beta-alanine ligase CCC13826_0583 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 157163886 Common tpx thiol peroxidase CCC13826_0758 5 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 157165684 Common - UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase CCC13826_0411 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 157164566 Common - hypothetical protein CCC13826_0759 2 None None None 157164682 Common - 50S ribosomal protein L25 (General stress protein CTC) CCC13826_0505 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 157165726 Common ribF riboflavin biosynthesis protein RibF CCC13826_2025 211 COG0196 RibF, FAD synthase Coenzyme metabolism 157165664 Common - 4'-phosphopantetheinyl transferase superfamily CCC13826_2164 6 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 157165275 Common metK methionine adenosyltransferase CCC13826_0068 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 157165608 Common - ATPase CCC13826_0948 9 None None None 157164378 Pathogen - hypothetical protein CCC13826_0014 1 None None None 157164188 Common - cytochrome c551 peroxidase (Cytochrome cperoxidase) CCC13826_0119 184 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 157164417 Common - DNA-directed RNA polymerase beta' chain CCC13826_1197 16 None None None 157165473 Common - sodium-dependent tyrosine transporter CCC13826_0213 2 None None None 157165521 Common lysS lysyl-tRNA synthetase CCC13826_0225 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 157165721 Common - hypothetical protein CCC13826_0860 9 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 157165456 Common modB molybdate ABC transporter, permease protein CCC13826_2102 167 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 157165672 Common - curli production assembly/transport component CsgG subfamily CCC13826_1131 34 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 157165403 Common - translation initiation factor IF-3 CCC13826_2136 24 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 157165532 Pathogen - hypothetical RNA pseudouridine synthase CCC13826_2289 1 None None None 157165491 Common - putative lipoprotein CCC13826_0730 5 None None None 157164494 Common - hypothetical protein CCC13826_0592 3 None None None 157164900 Common purF amidophosphoribosyltransferase CCC13826_1137 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 157165262 Pathogen - gamma-glutamyl phosphate reductase CCC13826_1479 1 None None None 157164777 Common - nickel-responsive regulator CCC13826_0355 65 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 157164706 Common - arabinose 5-phosphate isomerase CCC13826_1886 157 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 157164327 Common - putative soluble lytic murein transglycosylase CCC13826_0466 112 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 157165098 Common - secreted protein Hcp CCC13826_1188 28 COG3157 Hcp, Hemolysin-coregulated protein (uncharacterized) Function unknown 157165683 Common rpsK ribosomal protein S11 CCC13826_1753 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 157165517 Common - hypothetical protein CCC13826_0111 1 None None None 157164793 Common - hypothetical protein CCC13826_1524 21 COG3015 CutF, Uncharacterized lipoprotein NlpE involved in copper resistance Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism 157165428 Common - putative dihydropteroate synthase CCC13826_2021 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 157165440 Common - TM2 CCC13826_1809 6 None None None 157165580 Common - hypothetical protein CCC13826_1158 4 None None None 157165245 Common - transcriptional regulator, XRE family CCC13826_1613 70 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 157164846 Common - acyltransferase family protein CCC13826_2172 38 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 157165354 Common - hypothetical protein CCC13826_0377 2 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 157164153 Common - hypothetical protein CCC13826_1481 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 157164913 Common - hypothetical protein CCC13826_0727 1 None None None 157165537 Common - hypothetical protein CCC13826_0554 175 COG1496 COG1496, Uncharacterized conserved protein Function unknown 157165103 Common - hypothetical protein CCC13826_0983 19 COG0433 COG0433, Predicted ATPase General function prediction only 157164745 Common - hypothetical protein CCC13826_0653 1 None None None 157165555 Common - cytochrome c551 peroxidase (Cytochrome cperoxidase; CCP) CCC13826_1108 92 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 157163893 Pathogen - major outer membrane protein CCC13826_0382 1 None None None 157165362 Common dnaB replicative DNA helicase CCC13826_0681 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 157164943 Common nrdD anaerobic ribonucleoside-triphosphate reductase CCC13826_1897 107 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 157165162 Common - iron-sulfur cluster-binding domain protein CCC13826_0754 47 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 157165183 Common - methyl-accepting chemotaxis sensory transducer CCC13826_2088 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 157165228 Common moeB molybdopterin biosynthesis protein CCC13826_0494 152 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 157164961 Common - hypothetical protein CCC13826_1649 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 157164866 Common tyrS tyrosyl-tRNA synthetase CCC13826_0499 239 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157164655 Common - diaminopimelate dehydrogenase CCC13826_1251 15 COG3804 COG3804, Uncharacterized conserved protein related to dihydrodipicolinate reductase Function unknown 157165049 Common - ribosomal protein L7/L12 CCC13826_1195 56 COG3501 VgrG, Uncharacterized protein conserved in bacteria Function unknown 157165185 Common - glycosyl transferase, group 2 family protein CCC13826_0456 105 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 157163932 Common - putative response regulator of two-component system CCC13826_1580 223 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 157164100 Common ppk polyphosphate kinase CCC13826_1334 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 157163863 Common - putative phage integrase CCC13826_2077 91 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 157164485 Common - glycoprotease family CCC13826_1492 7 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 157163947 Common expD TonB system transport protein ExbD CCC13826_0393 121 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 157164292 Pathogen - hypothetical protein CCC13826_0931 1 None None None 157164442 Common - peptide methionine sulfoxide reductase MsrA/msrB CCC13826_0556 8 COG3878 COG3878, Uncharacterized protein conserved in bacteria Function unknown 157165382 Common yhbN cell envelope biogenesis protein YhbN CCC13826_1992 18 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 157165055 Common uvrC excinuclease ABC, C subunit CCC13826_1559 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 157165461 Common - polyphosphate kinase 2 superfamily CCC13826_2058 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 157163940 Common - phosphoribosylglycinamide formyltransferase CCC13826_2170 14 None None None 157164719 Common hemN oxygen-independent coproporphyrinogen III oxidase CCC13826_0887 208 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 157165512 Pathogen - chain A, Nikr In Open Conformation And Nickel Bound To High-Affinity Sites CCC13826_0790 1 None None None 157164780 Common - hypothetical protein CCC13826_2062 61 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 157163918 Pathogen - PilT CCC13826_1688 1 None None None 157165416 Pathogen - hypothetical protein CCC13826_0293 1 None None None 157164871 Common purS phosphoribosylformylglycinamidine synthase, PurS protein CCC13826_0133 114 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 157164619 Common pyrD dihydroorotate oxidase CCC13826_0118 222 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 157164473 Common - hypothetical protein CCC13826_1057 2 None None None 157165488 Common - spfh domain CCC13826_2108 53 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 157164918 Common - dihydrodipicolinate reductase (dhpr) CCC13826_1377 15 COG1565 COG1565, Uncharacterized conserved protein Function unknown 157164456 Common - adenine phosphoribosyltransferase (aprt) CCC13826_0530 202 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 157164712 Common - hypothetical protein CCC13826_0085 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 157164282 Common - peptidase family protein CCC13826_2017 117 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 157164730 Common slyD fkbp-type peptidyl-prolyl cis-trans isomerases 2 CCC13826_0094 27 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 157164675 Common - hypothetical protein CCC13826_1709 62 COG1133 SbmA, ABC-type long-chain fatty acid transport system, fused permease and ATPase components Lipid metabolism 157164426 Common - CheY protein CCC13826_0995 45 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157165323 Common - hypothetical protein CCC13826_0881 1 None None None 157165072 Common - malate dehydrogenase CCC13826_2254 165 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 157164099 Common hemH ferrochelatase CCC13826_0053 169 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 157164026 Common - type VI secretion protein, EvpB/family CCC13826_1182 50 COG3517 COG3517, Uncharacterized protein conserved in bacteria Function unknown 157165197 Common - hypothetical protein CCC13826_2145 10 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 157164889 Pathogen - hypothetical protein CCC13826_1243 1 None None None 157164533 Common yaeT outer membrane protein assembly complex, YaeT protein CCC13826_0942 163 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 157165717 Common - methyltransferase small domain family CCC13826_0147 87 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 157164592 Common rplR ribosomal protein L18 CCC13826_1760 142 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 157164838 Common - NADH-quinone oxidoreductase, b subunit subfamily CCC13826_1657 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 157165477 Common rplO ribosomal protein L15 CCC13826_1758 159 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 157164988 Common - oxidoreductase CCC13826_2297 111 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 157164116 Common tal transaldolase CCC13826_1583 147 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 157164084 Pathogen - transporter CCC13826_0854 1 None None None 157164981 Pathogen fliR flagellar biosynthetic protein CCC13826_1539 1 None None None 157164023 Common - hydrolase, carbon-nitrogen family CCC13826_0863 15 None None None 157164831 Pathogen - hypothetical protein CCC13826_1603 1 None None None 157164768 Common modA molybdate ABC transporter, periplasmic molybdate-binding protein CCC13826_2204 149 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 157164803 Common - ExsB CCC13826_0457 21 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 157164073 Common - addiction module toxin, RelE/StbE family CCC13826_0001 33 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 157164050 Common - hypothetical protein CCC13826_1568 3 None None None 157165210 Common yviF conserved protein YviF CCC13826_1732 7 None None None 157164395 Common - thiazole biosynthesis protein ThiH CCC13826_0052 40 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 157164524 Common - putative uracil-DNA glycosylase superfamily CCC13826_1620 99 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 157164670 Common - hypothetical protein CCC13826_0701 1 None None None 157164691 Common - histidine triad domain protein CCC13826_0143 121 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 157165544 Common flgG flagellar basal-body rod protein FlgG CCC13826_2184 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 157164956 Common - aspartate aminotransferase (transaminase a; aspat) CCC13826_1274 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 157163923 Common rfaF lipopolysaccharide heptosyltransferase II CCC13826_0479 102 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 157165499 Common - barstar (barnase inhibitor) superfamily CCC13826_0238 5 COG2732 COG2732, Barstar, RNAse (barnase) inhibitor Transcription 157165338 Common - 30S ribosomal protein S20 CCC13826_2150 1 None None None 157164651 Pathogen - hypothetical protein CCC13826_1298 1 None None None 157164022 Common fadD long-chain-fatty-acid--CoA ligase CCC13826_0279 193 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 157164081 Common - antibiotic biosynthesis monooxygenase CCC13826_0407 6 COG1359 COG1359, Uncharacterized conserved protein Function unknown 157165215 Common - diacylglycerol kinase (dagk; diglyceride kinase; dgk) CCC13826_1801 40 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 157165573 Common - putative 4-hydroxybenzoate polyprenyltransferase CCC13826_1159 117 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 157164765 Pathogen - hypothetical protein CCC13826_1192 1 None None None 157164450 Common - mce related protein CCC13826_0090 66 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 157165318 Common - putative 6-pyruvoyl tetrahydrobiopterin synthase (ptps; ptp synthase) CCC13826_1394 124 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 157164946 Pathogen - hypothetical protein CCC13826_0193 1 None None None 157165306 Pathogen - chemotaxis protein methyltransferase CCC13826_1077 2 None None None 157164858 Common ppa inorganic diphosphatase CCC13826_1978 187 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 157165469 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase CCC13826_1016 214 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 157164696 Common - yggt family protein CCC13826_0467 133 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 157164163 Common atpC ATP synthase F1, subunit epsilon CCC13826_0136 165 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 157165110 Common hypB hydrogenase accessory protein HypB CCC13826_1096 145 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 157164389 Common - protein of unknown function DUF81 CCC13826_0522 39 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157165325 Pathogen - hypothetical protein CCC13826_1971 1 None None None 157164185 Common - cation ABC transporter, permease protein CCC13826_2167 22 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 157164101 Pathogen - hypothetical protein CCC13826_0210 1 None None None 157165636 Pathogen - PQQ enzyme repeat domain protein CCC13826_1813 1 COG1520 COG1520, FOG: WD40-like repeat Function unknown 157165518 Common - elongation factor P (EF-P) CCC13826_1326 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 157165414 Common flgI flagellar P-ring protein FlgI CCC13826_1031 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 157164520 Common - hypothetical protein CCC13826_0714 4 None None None 157163912 Common - hypothetical protein CCC13826_0568 5 None None None 157164663 Pathogen - hypothetical protein CCC13826_1939 1 None None None 157164088 Common - hypothetical protein CCC13826_2128 133 COG2081 COG2081, Predicted flavoproteins General function prediction only 157164804 Common - molybdenum-pterin binding protein CCC13826_2152 175 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 157164018 Common - putative methyltransferase CCC13826_1032 177 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 157164032 Common ribC riboflavin synthase alpha subunit CCC13826_1547 72 COG0762 COG0762, Predicted integral membrane protein Function unknown 157164718 Common nrfG TPR-repeat-containing protein CCC13826_1313 11 COG5652 COG5652, Predicted integral membrane protein Function unknown 157165282 Common - Mur ligase middle domain family CCC13826_0109 154 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 157164493 Common - radical SAM enzyme, Cfr family CCC13826_2288 54 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 157164628 Common carB carbamoyl-phosphate synthase, large subunit CCC13826_2127 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 157164915 Common mraW S-adenosyl-methyltransferase MraW CCC13826_1083 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 157164851 Common - putative transcriptional activator CCC13826_2335 33 None None None 157165043 Common - chaperone protein HtpG (Heat shock protein htpG; High temperatureprotein G) CCC13826_2040 213 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 157164992 Common - thioredoxin family protein CCC13826_0769 14 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 157164445 Common - hypothetical protein CCC13826_1514 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 157164291 Common - response regulator receiver domain protein CCC13826_0980 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157164824 Common fecB iron chelatin ABC transporter, substrate binding protein CCC13826_0453 192 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157165492 Pathogen - methyltransferase small CCC13826_1170 2 None None None 157164306 Common - phosphatidylserine decarboxylase proenzyme CCC13826_0474 149 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157164095 Common - putative FAD binding domain CCC13826_1803 132 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 157165335 Common - phosphoribosylamine--glycine ligase CCC13826_0937 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 157164483 Common cysK cysteine synthase A CCC13826_1774 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 157165177 Common - putative methionyl-tRNA formyltransferase CCC13826_1522 50 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 157164614 Common cynT carbonic anyhydrase CCC13826_0771 4 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 157164125 Common gtp GTP-binding protein CCC13826_0526 128 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 157164059 Common - hypothetical protein CCC13826_1119 168 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 157165182 Pathogen - hypothetical protein CCC13826_1631 1 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 157165682 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase (Phosphatidylserine synthase) CCC13826_0991 103 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 157164760 Common flhB flagellar biosynthetic protein FlhB CCC13826_0999 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 157165548 Pathogen - bacteriophage replication gene A protein (GPA) CCC13826_2273 1 None None None 157165091 Pathogen - hypothetical protein CCC13826_2226 1 None None None 157164142 Common ttg2D toluene tolerance protein Ttg2D CCC13826_2201 48 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 157164315 Pathogen - hypothetical protein CCC13826_1572 1 None None None 157164671 Common - L-alanyl-D-glutamate peptidase CCC13826_1914 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 157165715 Pathogen - hypothetical protein CCC13826_1393 1 None None None 157164404 Common ilvN acetolactate synthase, small subunit CCC13826_0139 190 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 157165551 Common - exodeoxyribonuclease 7 large subunit CCC13826_0519 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 157165054 Common - transporter CCC13826_1311 68 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 157165589 Common - peptide ABC transporter, permease protein CCC13826_2118 208 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 157163880 Common - hypothetical protein CCC13826_1991 3 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 157165160 Common - hypothetical protein CCC13826_0880 2 None None None 157165586 Common - asparagine synthase, glutamine-hydrolyzing CCC13826_1516 4 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 157165002 Common modA molybdate ABC transporter, periplasmic molybdate-binding protein CCC13826_2101 45 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 157164027 Common - hypothetical protein CCC13826_1627 2 None None None 157164262 Common - tRNA pseudouridine synthase B CCC13826_1792 20 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 157165676 Common trpF N-(5'phosphoribosyl)anthranilate isomerase CCC13826_0970 189 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 157164873 Common - PAS/PAC sensor signal transduction histidine kinase CCC13826_1467 195 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 157164159 Common rpsE ribosomal protein S5 CCC13826_1759 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 157164296 Pathogen - hypothetical protein CCC13826_0034 2 None None None 157165158 Common moaE molybdopterin converting factor, subunit 2 CCC13826_2143 12 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 157163974 Common - twin arginine-targeting protein translocase, TatA/E family CCC13826_0544 68 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 157165535 Common hisA phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase CCC13826_0444 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 157164506 Pathogen - bacteriophage replication gene A protein (GPA) CCC13826_0020 6 None None None 157164840 Common - prephenate dehydrogenase CCC13826_0943 167 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 157165123 Common - dihydrodipicolinate synthase (dhdps) CCC13826_1145 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 157165763 Common - mature parasite-infected erythrocyte surface antigen CCC13826_1341 180 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 157163995 Common - hypothetical protein CCC13826_1309 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 157164798 Common thiS thiamine biosynthesis protein ThiS CCC13826_1275 5 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 157165462 Common hisC histidinol-phosphate aminotransferase CCC13826_1590 236 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 157164120 Common - guanylate kinase (GMP kinase) CCC13826_1537 186 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 157164242 Pathogen - hypothetical protein CCC13826_0642 2 None None None 157164183 Pathogen - hypothetical protein CCC13826_2028 1 None None None 157165725 Common apt adenine phosphoribosyltransferase CCC13826_1608 175 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 157164078 Common - putative periplasmic protein CCC13826_2091 2 None None None 157164412 Common - hypothetical protein CCC13826_2092 7 None None None 157165257 Common - probable pyridine nucleotide-disulfide oxidoreductase YkgC CCC13826_1578 12 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 157165167 Common - hypothetical protein CCC13826_1028 4 None None None 157164603 Common - DegT/DnrJ/EryC1/StrS aminotransferase family CCC13826_2049 190 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 157165515 Common - ExsB protein CCC13826_1538 177 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 157164325 Common - lipoprotein CCC13826_0638 91 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 157164741 Common - ankyrin repeat protein CCC13826_1980 224 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 157164681 Pathogen - binding-protein-dependent transport systems inner membrane component CCC13826_1948 1 None None None 157164898 Common - NAD(FAD)-utilizing dehydrogenase CCC13826_1875 82 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 157163917 Common - flagellar P-ring protein (Basal body P-ring protein) CCC13826_1254 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 157164875 Common hemL glutamate-1-semialdehyde-2,1-aminomutase CCC13826_0834 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 157165479 Common - oxidoreductase htatip2 CCC13826_1901 45 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 157163898 Common - putative tungsten ABC transporter, ATP-binding protein CCC13826_1662 181 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 157163907 Common - putative Cell division protease FtsH homolog CCC13826_0441 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 157165466 Common - PepSY-associated TM helix family CCC13826_1718 22 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 157164429 Common - Dyp-type peroxidase CCC13826_1987 137 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 157165739 Pathogen - hypothetical protein CCC13826_2078 1 None None None 157163997 Common - SpoU rRNA methylase family protein CCC13826_1815 169 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 157164479 Common fabD malonyl CoA-acyl carrier protein transacylase CCC13826_0926 208 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 157164708 Common ybbB tRNA 2-selenouridine synthase CCC13826_0142 65 COG2603 COG2603, Predicted ATPase General function prediction only 157163905 Pathogen - hypothetical protein CCC13826_1167 1 None None None 157164883 Common - enolase (2-phosphoglycerate dehydratase; 2-phospho-D-glycerate hydro-lyase) CCC13826_1910 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 157164661 Common - hypothetical protein CCC13826_1558 2 None None None 157165527 Common - hydrogenase-4 component I CCC13826_1459 3 None None None 157164384 Pathogen - hypothetical protein CCC13826_1510 1 None None None 157164907 Pathogen nifR nitrogen regulation protein nifR3 CCC13826_1349 1 None None None 157164927 Common smpB SsrA-binding protein CCC13826_0060 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 157165520 Common ftsH cell division protein CCC13826_2037 1 None None None 157165345 Common fbp fructose-1,6-bisphosphatase CCC13826_1544 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 157164578 Pathogen - hypothetical protein CCC13826_1152 1 None None None 157164737 Common - hypothetical protein CCC13826_1604 1 None None None 157164365 Common xerC integrase/recombinase CCC13826_1130 1 COG4259 COG4259, Uncharacterized protein conserved in bacteria Function unknown 157164042 Common gpmI 2,3-bisphosphoglycerate-independent phosphoglycerate mutase CCC13826_0563 127 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 157164837 Common - MoeA N- region (domain I and II) protein CCC13826_1266 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 157165209 Common dnaA chromosomal replication initiator protein DnaA CCC13826_1853 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 157164532 Common - radical SAM enzyme, Cfr family CCC13826_1892 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 157164338 Common tyrS tyrosyl-tRNA synthetase CCC13826_1296 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 157164171 Common - anthranilate synthase component II CCC13826_0023 5 COG2932 COG2932, Predicted transcriptional regulator Transcription 157164216 Common - hypothetical protein CCC13826_0952 7 COG4268 McrC, McrBC 5-methylcytosine restriction system component Defense mechanisms 157164222 Pathogen - hypothetical protein CCC13826_0010 1 None None None 157164909 Common - hypothetical protein CCC13826_1679 17 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 157165147 Common prfA peptide chain release factor 1 CCC13826_1805 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 157165248 Common - peptidyl-prolyl cis-trans isomerase B (PPIase B; Rotamase B) CCC13826_0432 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 157164076 Common kdsA 3-deoxy-8-phosphooctulonate synthase CCC13826_0779 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 157163949 Pathogen hyfB hydrogenase-4 component B CCC13826_2310 1 None None None 157165251 Pathogen - putative ABC transport system periplasmic substrate-binding protein CCC13826_1116 1 None None None 157164925 Common galE UDP-glucose 4-epimerase CCC13826_0464 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 157164653 Common - cell division protein FtsY CCC13826_2186 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 157164636 Common - putative ABC transporter, ATP-binding protein CCC13826_1745 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 157164275 Common - putative FAD dependent oxidoreductase CCC13826_1160 18 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 157164817 Pathogen - hypothetical protein CCC13826_1820 1 None None None 157164610 Common - protein TolB CCC13826_0922 124 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 157164317 Common - threonine dehydratase CCC13826_1984 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 157163962 Common - L-seryl-tRNA(Sec) selenium transferase CCC13826_0688 49 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 157164419 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase CCC13826_1265 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 157164167 Common - hypothetical bacteriophage protein CCC13826_0753 6 None None None 157164474 Common lepB signal peptidase I CCC13826_0831 144 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 157165508 Common - ATP-dependent DNA helicase, UvrD/REP family CCC13826_1482 122 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 157163942 Pathogen - Tat (twin-arginine translocation) pathway signal sequence domain protein CCC13826_0206 1 None None None 157164864 Common - sodium/hydrogen exchanger family protein CCC13826_1292 71 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 157165565 Common dgkA diacylglycerol kinase CCC13826_2155 2 None None None 157163984 Common - hypothetical protein CCC13826_0903 15 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 157164982 Common - putative iron-regulated membrane protein CCC13826_0224 201 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 157163859 Common hisB imidazoleglycerol-phosphate dehydratase CCC13826_1989 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 157165258 Common - hypothetical protein CCC13826_1306 2 None None None 157164207 Pathogen - hypothetical protein CCC13826_2264 1 None None None 157165023 Pathogen - hypothetical protein CCC13826_0025 1 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 157165775 Pathogen - protein yitk CCC13826_2274 1 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 157164113 Common cvpA CvpA family protein CCC13826_0223 7 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 157164331 Common - DNA gyrase subunit A CCC13826_0843 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 157165396 Common - multidrug resistance protein, SMR family CCC13826_0663 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 157163953 Common atpH ATP synthase F1, delta subunit CCC13826_0914 40 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 157164144 Common trxB thioredoxin-disulfide reductase CCC13826_1140 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 157164348 Common ffh signal recognition particle protein CCC13826_1012 60 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 157165119 Common gltX glutamyl-tRNA synthetase CCC13826_1548 247 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 157164543 Common - nucleotide sugar dehydrogenase subfamily CCC13826_0463 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 157164601 Pathogen - hypothetical protein CCC13826_1904 1 None None None 157164568 Common - hypothetical protein CCC13826_1451 47 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 157164939 Common - cache domain family CCC13826_0840 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 157165594 Common cas crispr-associated protein Cas2 CCC13826_1424 24 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 157164280 Common glmM phosphoglucosamine mutase CCC13826_1807 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 157163876 Common rplW ribosomal protein L23 CCC13826_0353 82 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 157165138 Pathogen - hypothetical protein CCC13826_2195 1 None None None 157164910 Common fliM flagellar motor switch protein FliM CCC13826_1020 106 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 157165738 Common - transporter, auxin efflux carrier (AEC) family CCC13826_1322 96 COG0679 COG0679, Predicted permeases General function prediction only 157164511 Pathogen - putative beta-lactamase HcpC (Cysteine-richprotein C) CCC13826_0310 1 None None None 157164199 Pathogen fliS flagellar protein CCC13826_1259 1 None None None 157165689 Common - hypothetical protein CCC13826_1238 166 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 157164563 Common - hypothetical protein CCC13826_2019 7 None None None 157165621 Common cydB cytochrome D ubiquinol oxidase, subunit II CCC13826_0905 145 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 157164238 Common - modulator of drug activity B CCC13826_1626 38 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 157165270 Common - thiamine-phosphate pyrophosphorylase CCC13826_0338 20 None None None 157164539 Common - putative phage integrase CCC13826_1645 2 None None None 157165690 Common - hypothetical protein CCC13826_1617 25 COG3610 COG3610, Uncharacterized conserved protein Function unknown 157165087 Common serA phosphoglycerate dehydrogenase CCC13826_1569 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 157165212 Common rpsQ ribosomal protein S17 CCC13826_1768 214 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 157165063 Common ifcA fumarate reductase flavoprotein subunit CCC13826_1912 34 COG4237 HyfE, Hydrogenase 4 membrane component (E) Energy production and conversion 157165193 Pathogen - DedA family protein CCC13826_0083 1 None None None 157165170 Common - putative RDD family CCC13826_1846 7 None None None 157165014 Common fliF flagellar M-ring protein FliF CCC13826_1591 128 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 157165490 Common - peptidase family S51 CCC13826_1040 32 COG3340 PepE, Peptidase E Amino acid transport and metabolism 157164068 Common ribD riboflavin biosynthesis protein RibD CCC13826_1500 200 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 157165680 Common hypC hydrogenase assembly chaperone HypC/HupF CCC13826_1095 96 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 157164548 Common - cytosol aminopeptidase family, catalytic domain CCC13826_1606 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 157164958 Common - hypothetical protein CCC13826_1728 13 None None None 157164229 Common - hypothetical protein CCC13826_1171 6 None None None 157165294 Common mfd transcription-repair coupling factor CCC13826_0078 220 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 157164253 Common ylxH ATP-binding protein CCC13826_0801 26 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 157164973 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase CCC13826_0064 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 157164070 Pathogen - hypothetical protein CCC13826_0729 1 None None None 157165453 Pathogen - 30S ribosomal protein S5 (BS5) CCC13826_0265 1 None None None 157165475 Pathogen tviB UDP-glucose/GDP-mannose dehydrogenase family CCC13826_0348 1 None None None 157164820 Common - divalent cation transporter CCC13826_2056 203 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 157165140 Common - hypothetical protein CCC13826_1438 97 COG0327 COG0327, Uncharacterized conserved protein Function unknown 157165131 Common - ABC transporter, ATP-binding protein CCC13826_0232 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 157164439 Common - GTP pyrophosphokinase CCC13826_0500 208 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 157165238 Common - hypothetical protein CCC13826_1660 6 None None None 157164666 Pathogen - hypothetical protein CCC13826_2275 1 None None None 157165422 Common - thioesterase superfamily CCC13826_2061 10 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 157165075 Pathogen - hypothetical protein CCC13826_1644 1 None None None 157164978 Common rpmA ribosomal protein L27 CCC13826_0996 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 157164599 Common - flagellar biosynthetic protein FliQ CCC13826_1906 20 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 157164810 Common - putative periplasmic protein CCC13826_0101 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 157165745 Pathogen - hypothetical protein CCC13826_1747 2 None None None 157164728 Common flgK flagellar hook-associated protein FlgK CCC13826_0708 100 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 157165433 Common - oxidoreductase CCC13826_2298 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 157165315 Common iadA beta-aspartyl peptidase CCC13826_0178 24 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 157165070 Pathogen pnp polyribonucleotide nucleotidyltransferase CCC13826_0933 1 None None None 157165240 Pathogen - hypothetical protein CCC13826_0953 1 None None None 157165037 Common mog molybdopterin biosynthesis protein CCC13826_2038 9 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 157164621 Common - GTP-dependent nucleic acid-binding protein EngD CCC13826_1605 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 157164002 Common - putative ABC transporter, ATP-binding protein CCC13826_0414 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 157165747 Common - C4-dicarboxylate transporter family protein, DctQ subunit CCC13826_0425 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 157165411 Common - putative anaerobic dehydrogenase CCC13826_2315 182 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 157165656 Common - amino acid ABC tansporter, permease protein, His/Glu/Gln/Arg/opine family CCC13826_0966 213 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157164770 Common - hypothetical protein CCC13826_2020 29 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 157165651 Common - phenylalanyl-tRNA synthetase alpha chain (Phenylalanine--tRNA ligase alpha chain; PheRS) CCC13826_0483 3 None None None 157164030 Common - hypothetical protein CCC13826_1407 34 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 157165205 Common - aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit C (Asp/Glu-ADT subunit C) CCC13826_1687 27 None None None 157165702 Common - hypothetical protein CCC13826_0838 5 None None None 157164285 Common - hypothetical protein CCC13826_0230 63 None None None 157165750 Pathogen - Mrr restriction system protein (EcoKMrr) CCC13826_0974 2 None None None 157165662 Common - stage 0 sporulation protein J CCC13826_0358 182 COG1475 Spo0J, Predicted transcriptional regulators Transcription 157164616 Pathogen - hypothetical protein CCC13826_1038 1 None None None 157164762 Pathogen - hypothetical protein CCC13826_0314 1 None None None 157164639 Pathogen - ribosomal protein L11 methyltransferase (L11 Mtase) CCC13826_0994 1 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 157165313 Common fabZ beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ CCC13826_2122 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 157164964 Pathogen - hypothetical protein CCC13826_0197 1 None None None 157165386 Common rplB ribosomal protein L2 CCC13826_0352 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 157165675 Common - nodulation efficiency protein D (NfeD) CCC13826_1526 4 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 157164826 Common - fructose-bisphosphate aldolase CCC13826_0901 9 None None None 157165045 Common - 5'-nucleotidase SurE (Nucleoside 5'-monophosphatephosphohydrolase) CCC13826_0495 33 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 157164990 Pathogen - activator of (R)-2-hydroxyglutaryl-CoA dehydratase CCC13826_1316 1 None None None 157164459 Pathogen - hypothetical protein CCC13826_1710 1 None None None 157164658 Common - hypothetical protein CCC13826_1229 5 None None None 157164256 Common - CmeA CCC13826_1640 158 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 157164304 Common - Omp18 CCC13826_0923 147 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 157165707 Common fbaA fructose-bisphosphate aldolase, class II CCC13826_2070 172 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 157164716 Common upp uracil phosphoribosyltransferase CCC13826_0240 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 157164477 Common serB phosphoserine phosphatase SerB CCC13826_1582 152 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 157164963 Common frdC fumarate reductase CCC13826_0978 182 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 157165752 Common ftsW_ bacterial cell division membrane protein FtsW/MrdB/SpoVE CCC13826_1503 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 157164893 Pathogen - hypothetical protein CCC13826_0652 1 None None None 157165333 Pathogen - radical SAM domain protein CCC13826_1099 6 None None None 157164064 Common - transcriptional regulator, ModE family CCC13826_1804 73 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 157164278 Pathogen - addiction module toxin, RelE/StbE family CCC13826_2095 1 None None None 157165284 Common - glutamine-binding periplasmic protein/glutamine transport system permease protein CCC13826_1927 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 157163919 Pathogen - putative periplasmic protein CCC13826_1074 1 None None None 157165180 Common - putative cytochrome C-type haem-binding periplasmic protein CCC13826_1398 26 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 157164698 Common - putative diguanylate cyclase CCC13826_2174 44 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 157165336 Common - hypothetical protein CCC13826_0833 7 COG5373 COG5373, Predicted membrane protein Function unknown 157164673 Common - hypothetical protein CCC13826_0220 7 None None None 157163865 Common - SRC Kinase Associated Phosphoprotein 2 CCC13826_0176 32 COG2259 COG2259, Predicted membrane protein Function unknown 157164726 Common folB dihydroneopterin aldolase CCC13826_0981 6 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 157164039 Common - hypothetical protein CCC13826_1543 6 None None None 157165059 Common - putative methyltransferase CCC13826_2026 52 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 157164783 Common lemA cytoplasmic membrane protein CCC13826_0209 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 157164452 Pathogen - hypothetical protein CCC13826_2002 1 None None None 157165356 Common dapB dihydrodipicolinate reductase CCC13826_1138 217 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 157165104 Common - putative aminotransferase CCC13826_1678 2 None None None 157164856 Common - ncair mutase CCC13826_1004 70 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 157165047 Common - hypothetical protein CCC13826_0535 9 COG2520 COG2520, Predicted methyltransferase General function prediction only 157165571 Common - LemA protein CCC13826_1702 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 157165304 Common - NapC/NirT Cytochrome c family, N- region CCC13826_1831 54 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 157164763 Common - uroporphyrinogen III synthase HEM4 CCC13826_0938 7 None None None 157163976 Common - putative Cytochrome c-type haem-binding periplasmic protein CCC13826_1120 19 None None None 157163921 Pathogen - hypothetical protein CCC13826_1284 1 None None None 157164464 Common - hypothetical protein CCC13826_0728 7 None None None 157164245 Common - tryptophanyl-tRNA synthetase (Tryptophan--tRNA ligase; TrpRS) CCC13826_0669 10 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 157164806 Common mrdA penicillin-binding protein 2 CCC13826_1995 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 157165316 Common - 3-deoxy-7-phosphoheptulonate synthase CCC13826_0150 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 157165467 Common - putative peptide ABC transporter, permease protein CCC13826_1885 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 157165113 Common - penicillin-binding protein CCC13826_0075 7 None None None 157164344 Common accC acetyl-CoA carboxylase, biotin carboxylase CCC13826_2104 235 COG0439 AccC, Biotin carboxylase Lipid metabolism 157164103 Common rpsQ 30S ribosomal protein S17 CCC13826_0274 5 None None None 157165497 Common - hypothetical protein CCC13826_1931 17 COG4378 COG4378, Uncharacterized protein conserved in bacteria Function unknown 157164529 Pathogen - 2-hydroxyglutaryl-CoA dehydratase, D-component CCC13826_1317 1 None None None 157165189 Common czcD cation-efflux system membrane protein CCC13826_1066 86 COG0789 SoxR, Predicted transcriptional regulators Transcription 157164733 Common - putative maltosaccharide ABC transporter, maltosaccharide-binding protein CCC13826_1295 44 COG1146 COG1146, Ferredoxin Energy production and conversion 157164025 Common - permease CCC13826_0691 93 COG1291 MotA, Flagellar motor component Cell motility and secretion 157163914 Common fliI flagellar protein export ATPase FliI CCC13826_1777 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 157164940 Common - methylated-DNA-[protein]-cysteine S-methyltransferase CCC13826_1409 192 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 157165347 Common fliL flagellar basal body-associated protein FliL CCC13826_1320 42 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 157163930 Common - campylobacter major outer membrane protein CCC13826_2060 2 None None None 157165612 Common - glyoxalase II CCC13826_1402 73 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 157164834 Common - periplasmic protein CCC13826_0889 29 COG3672 COG3672, Predicted periplasmic protein Function unknown 157164260 Pathogen - hypothetical protein CCC13826_0325 1 None None None 157164504 Pathogen - hypothetical protein CCC13826_0291 2 None None None 157165408 Common - hypothetical protein CCC13826_1653 1 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 157165765 Pathogen - hypothetical protein CCC13826_0532 3 None None None 157164589 Common ruvA holliday junction DNA helicase RuvA CCC13826_0113 208 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 157165655 Common - DJ-1/PfpI family protein CCC13826_2139 86 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 157165096 Common - band 7/Mec-2 family protein CCC13826_1525 206 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 157164289 Common murI glutamate racemase CCC13826_1245 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 157164016 Common mda modulator of drug activity CCC13826_0548 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 157164508 Common - permeases of the drug/metabolite transporter CCC13826_1796 83 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 157165460 Common - hypothetical protein CCC13826_1146 4 None None None 157164121 Common recR recombination protein RecR CCC13826_0968 203 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 157165513 Common dprA DNA protecting protein DprA CCC13826_2005 207 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 157163955 Common - argininosuccinate lyase (arginosuccinase; asal) CCC13826_0439 146 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 157165260 Pathogen - transformation system protein CCC13826_1059 1 None None None 157164323 Common tgt queuine tRNA-ribosyltransferase CCC13826_0093 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 157165485 Pathogen - DJ-1/PfpI family protein CCC13826_1863 1 None None None 157164490 Common pabC aminodeoxychorismate lyase CCC13826_0100 99 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 157165165 Common fliG flagellar motor switch protein CCC13826_0513 232 COG0623 FabI, Enoyl- acyl-carrier-protein 157164930 Common - hypothetical protein CCC13826_2116 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 157164269 Pathogen - putative ferric uptake regulation protein CCC13826_2161 1 None None None 157164011 Common - methyl-accepting chemotaxis protein (MCP) signaling domain CCC13826_1957 120 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 157164053 Pathogen ahpC alkyl hydroperoxide reductase CCC13826_2249 1 None None None 157165191 Common purA adenylosuccinate synthetase CCC13826_2131 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 157163882 Common ilvB acetolactate synthase, large subunit, biosynthetic type CCC13826_0140 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 157165060 Common - preprotein translocase, SecY subunit CCC13826_1757 217 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 157164087 Common mtnN MTA/SAH nucleosidase CCC13826_0927 99 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 157164842 Common - iron compounds ABC transporter, ATP-binding protein CCC13826_1532 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 157165364 Pathogen - hypothetical protein CCC13826_0196 1 None None None 157165090 Common rbfA ribosome-binding factor A CCC13826_1496 8 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 157164495 Common prrB anti-codon nuclease masking agent CCC13826_1975 12 None None None 157163990 Common - disulfide isomerase CCC13826_1893 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 157165760 Common - hypothetical protein CCC13826_1081 3 None None None 157165052 Pathogen - hypothetical protein CCC13826_2312 1 None None None 157165584 Pathogen - GTP-binding protein CCC13826_0954 1 None None None 157165236 Common hemE uroporphyrinogen decarboxylase CCC13826_1013 180 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 157165605 Pathogen - putative nucleotide phosphoribosyltransferase CCC13826_0408 1 None None None 157165405 Common - OmpA/MotB CCC13826_0895 28 COG3672 COG3672, Predicted periplasmic protein Function unknown 157163889 Common rpmB ribosomal protein L28 CCC13826_1345 167 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 157164376 Common - homoserine kinase (HSK; HK) CCC13826_0413 185 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 157164157 Common - permease, cytosine/purines, uracil, thiamine, allantoin family CCC13826_0157 67 COG1457 CodB, Purine-cytosine permease and related proteins Nucleotide transport and metabolism 157164632 Common - hypothetical protein CCC13826_2193 10 None None None 157164402 Pathogen - foldase protein PrsA CCC13826_0902 1 None None None 157165269 Pathogen - hypothetical protein CCC13826_0141 1 None None None 157165351 Common - hypothetical protein CCC13826_0874 1 None None None 157164341 Common fdhD FdhD protein CCC13826_1669 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 157164641 Pathogen - tRNA 2-selenouridine synthase (Selenophosphate-dependenttRNA 2-selenouridine synthase) CCC13826_1165 1 None None None 157164178 Common - site-specific recombinase, phage integrase family CCC13826_1607 106 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 157164049 Pathogen - GatB/Yqey family protein CCC13826_0604 1 None None None 157165253 Common - glutamine synthetase 1 CCC13826_0367 244 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 157164634 Common - type II secretion system protein E CCC13826_0588 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 157164201 Common - hypothetical protein CCC13826_2192 40 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 157164302 Common - hypothetical protein CCC13826_0815 2 None None None 157164648 Common - large repetitive protein CCC13826_0899 84 None None None 157164200 Common - phosphoribosylaminoimidazole carboxylase CCC13826_1228 12 COG2842 COG2842, Uncharacterized ATPase, putative transposase General function prediction only 157165200 Common - hydrogenase-4 component G CCC13826_1457 10 None None None 157165503 Common - response regulator receiver domain protein CCC13826_1969 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157165227 Common napB periplasmiC nitrate reductase, diheme cytochrome c subunit CCC13826_0865 37 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 157164514 Common - putative outer membrane component of efflux system CCC13826_0894 35 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 157165394 Common - hypothetical protein CCC13826_1494 2 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 157165777 Common - molybdopterin oxidoreductase domain protein CCC13826_0200 194 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 157164605 Common - hypothetical protein CCC13826_1824 11 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 157164333 Pathogen - carbon monoxide dehydrogenase 1 (codh 1) CCC13826_1945 1 None None None 157163960 Common - bacterial type II and III secretion system protein CCC13826_1211 48 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 157165327 Pathogen - conserved Prokaryal protein CCC13826_1241 2 None None None 157164472 Common - hypothetical protein CCC13826_0721 159 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 157164949 Common - aspartate carbamoyltransferase (Aspartatetranscarbamylase; ATCase) CCC13826_0309 2 None None None 157165246 Common - hypothetical protein CCC13826_0164 2 None None None 157165713 Common - glyceraldehyde-3-phosphate dehydrogenase 2 CCC13826_1508 184 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 157164273 Common - nucleotidyl transferase CCC13826_2301 230 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 157165175 Common ttrA tetrathionate reductase subunit A CCC13826_0003 26 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 157164881 Common - cysteine-rich domain protein CCC13826_1281 49 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 157164985 Pathogen - hypothetical protein CCC13826_2130 1 None None None 157164105 Common - hypothetical protein CCC13826_1018 123 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 157164386 Common - hypothetical protein CCC13826_1005 10 None None None 157164399 Common - hypothetical protein CCC13826_1609 4 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 157164527 Common ansB L-asparaginase II CCC13826_1009 114 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 157165121 Common - putative DNA polymerase III, subunits gamma and tau CCC13826_1448 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 157164996 Common - 3' exoribonuclease family, domain 2 CCC13826_0488 234 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 157163903 Common - mechanosensitive ion channel family protein CCC13826_1107 167 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 157164849 Common - peptidase T (Tripeptide aminopeptidase; Aminotripeptidase; Tripeptidase) CCC13826_0644 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 157164212 Pathogen - hypothetical protein CCC13826_1210 1 COG4128 Zot, Zonula occludens toxin General function prediction only 157164735 Pathogen psp ribonuclease, PSP-type CCC13826_0374 1 None None None 157163874 Common - hypothetical protein CCC13826_1964 4 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 157164905 Common fmt methionyl-tRNA formyltransferase CCC13826_0347 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 157165623 Common aspS aspartyl-tRNA synthetase CCC13826_1981 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157164218 Common - hypothetical protein CCC13826_0849 55 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 157165220 Common - abc transporter, ATP-binding protein CCC13826_0228 2 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 157165000 Common trpA tryptophan synthase, alpha subunit CCC13826_0973 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 157164530 Common - hypothetical protein CCC13826_1444 5 None None None 157165464 Common rpsN ribosomal protein S14p/S29e CCC13826_1764 180 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 157164789 Common - NosL protein CCC13826_1878 17 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 157165145 Pathogen - nucleoside diphosphate kinase (NDK; NDP kinase; Nucleoside-2-P kinase) CCC13826_1212 1 None None None 157165759 Common - histidinol phosphatase CCC13826_0366 223 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 157163989 Common putP proline permease CCC13826_0967 158 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 157163968 Common - sugar efflux transporter B CCC13826_1932 190 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 157165560 Common dnaK chaperone and heat shock protein 70 CCC13826_0302 31 COG5410 COG5410, Uncharacterized protein conserved in bacteria Function unknown 157164799 Common priA primosomal protein N' CCC13826_0678 204 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 157164232 Common - ATP-dependent Clp protease proteolytic subunit (Endopeptidase Clp) CCC13826_2175 24 COG4648 COG4648, Predicted membrane protein Function unknown 157165203 Common - UvrABC system protein A (UvrA protein; Excinuclease ABC subunit A) CCC13826_1216 150 COG1610 COG1610, Uncharacterized conserved protein Function unknown 157165279 Pathogen - hypothetical protein CCC13826_1823 1 None None None 157164623 Common - triosephosphate isomerase (TIM; Triose-phosphateisomerase) CCC13826_1506 75 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 157164822 Pathogen - glutamyl-tRNA synthetase (Glutamate--tRNA ligase; GluRS) CCC13826_0929 1 None None None 157164750 Common - flagellar motor switch protein CCC13826_1019 112 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 157164435 Common - putative periplasmic protein CCC13826_0135 7 None None None 157165081 Common - aminobenzoyl-glutamate utilization protein A CCC13826_0797 163 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 157164392 Common - hypothetical protein CCC13826_1970 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 157164355 Pathogen - bacteriophage replication gene A protein (GPA) CCC13826_0189 1 None None None 157164423 Common - hypothetical protein CCC13826_1225 4 None None None 157164885 Common - putative endoribonuclease L-PSP CCC13826_1697 188 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 157165781 Common - hypothetical protein CCC13826_1652 1 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 157165233 Pathogen - periplasmic protein-probably involved in high-affinity fe2+ transport CCC13826_0679 1 None None None 157164668 Common - transferase hexapeptide repeat CCC13826_0541 138 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 157164009 Common - hydrolase, carbon-nitrogen family CCC13826_0657 202 COG0388 COG0388, Predicted amidohydrolase General function prediction only 157164469 Common - hypothetical protein CCC13826_0282 4 COG4258 COG4258, Predicted exporter General function prediction only 157165610 Common - TrkA domain protein CCC13826_1346 83 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 157164231 Common plsX fatty acid/phospholipid synthesis protein PlsX CCC13826_0987 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 157165435 Pathogen - periplasmic binding protein CCC13826_0802 1 None None None 157165009 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CCC13826_0803 2 COG2245 COG2245, Predicted membrane protein Function unknown 157165033 Common - purine nucleoside phosphorylase CCC13826_1078 64 COG1683 COG1683, Uncharacterized conserved protein Function unknown 157164287 Common lysA diaminopimelate decarboxylase dap decarboxylase CCC13826_0508 12 COG3401 COG3401, Fibronectin type 3 domain-containing protein General function prediction only 157164771 Pathogen - ggdef domain protein CCC13826_1779 1 None None None 157164136 Pathogen - hypothetical protein CCC13826_1684 1 None None None 157165736 Common soj SpoOJ regulator CCC13826_0794 17 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 157165699 Common - hypothetical protein CCC13826_0684 28 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 157164000 Common uppS di-trans,poly-cis-decaprenylcistransferase CCC13826_0695 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 157165035 Common - hypothetical protein CCC13826_0395 12 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 157164127 Common - hypothetical protein CCC13826_2295 9 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 157164951 Common murG undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase CCC13826_1242 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 157164574 Common - glutamate-1-semialdehyde 2,1-aminomutase CCC13826_1085 82 None None None 157165016 Common - sodium:neurotransmitter symporter family CCC13826_1504 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 157165740 Common - putative cytochrome c family protein CCC13826_0383 3 None None None 157163944 Common fabE biotin carboxyl carrier protein CCC13826_1900 167 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 157165704 Common - lipoprotein CCC13826_1586 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 157165423 Common - seryl-tRNA synthetase (Serine--tRNA ligase; SerRS) CCC13826_0671 69 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 157165025 Common - Rrf2 family protein CCC13826_1071 152 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 157164580 Common - probable addiction module antidote protein CCC13826_1426 34 COG3636 COG3636, Predicted transcriptional regulator Transcription 157165525 Common - geranyltranstransferase (Farnesyl-diphosphate synthase; FPP synthase) CCC13826_1736 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 157164554 Common - hypothetical protein CCC13826_1475 40 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 157165065 Common - tRNA synthetase, class II CCC13826_1871 5 None None None 157164197 Common - hypothetical protein CCC13826_0148 51 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 157165506 Common - acetoacetate metabolism regulatory protein AtoC CCC13826_0846 181 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 157165603 Common cysS cysteinyl-tRNA synthetase CCC13826_0116 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157163928 Common - putative site-specific DNA methyltransferase CCC13826_1255 231 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 157163935 Common - 60 kDa chaperonin (Protein Cpn60; groEL protein) CCC13826_0873 31 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 157165619 Common - aerobic C4-dicarboxylate transport protein CCC13826_0431 17 COG3738 COG3738, Uncharacterized protein conserved in bacteria Function unknown 157165085 Common fliR flagellar biosynthetic protein FliR CCC13826_0547 124 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 157165634 Common - transporter, monovalent cation:proton antiporter-2 (CPA2) family CCC13826_1067 212 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 157164612 Common ligA DNA ligase, NAD-dependent CCC13826_2023 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 157164751 Common - molybdopterin oxidoreductase Fe4S4 domain family CCC13826_2032 184 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 157164819 Common fabF beta ketoacyl-acyl carrier protein synthase II CCC13826_1552 21 None None None 157164432 Common ubiA 4-hydroxybenzoate octaprenyltransferase CCC13826_1399 47 COG2510 COG2510, Predicted membrane protein Function unknown 157164255 Common - hypothetical protein CCC13826_1523 8 COG3015 CutF, Uncharacterized lipoprotein NlpE involved in copper resistance Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism 157164309 Common - cell division CCC13826_0575 133 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 157165371 Common metX homoserine O-acetyltransferase CCC13826_0275 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 157165296 Common - macrolide export ATP-binding/permease protein MacB CCC13826_1257 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 157165649 Common - DNA-binding response regulator CCC13826_2064 33 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 157164015 Common - trimethylamiNe-n-oxide reductase 1 (tmaoreductase 1; trimethylamine oxidase 1) CCC13826_0958 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 157164517 Common - methyl-accepting chemotaxis protein CCC13826_1729 45 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 157164321 Common - hypothetical protein CCC13826_2158 88 None None None 157164350 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase CCC13826_0122 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 157164747 Common rfaD ADP-glyceromanno-heptose 6-epimerase CCC13826_0576 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 157164055 Common - hypothetical protein CCC13826_0264 1 None None None 157165711 Pathogen - CmeU CCC13826_1044 1 None None None 157164295 Common - hypothetical protein CCC13826_1616 46 COG2966 COG2966, Uncharacterized conserved protein Function unknown 157163885 Common - Hsp12 variant C CCC13826_2197 66 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 157164593 Common - anaeroBic dimethyl sulfoxide reductase chain b (dmso reductase iron-sulfur subunit) CCC13826_0388 166 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 157163892 Common - acetyltransferase, gnat family CCC13826_1712 122 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 157164481 Common ribA GTP cyclohydrolase II CCC13826_0883 173 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 157164746 Common - hypothetical protein CCC13826_0446 13 None None None 157164248 Pathogen hydA quinone-reactive Ni/Fe hydrogenase, small subunit CCC13826_1126 1 None None None 157164400 Common - aminoacyl-histidine dipeptidase CCC13826_2041 39 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 157165556 Common - abc transport protein CCC13826_0675 2 None None None 157165622 Common xerC integrase/recombinase CCC13826_0002 24 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 157164685 Common - abc transport permease protein-involved in lipoprotein release CCC13826_0677 19 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 157165366 Common rbn tRNA-processing ribonuclease BN CCC13826_2059 3 COG3399 COG3399, Uncharacterized protein conserved in bacteria Function unknown 157163867 Common - (3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase ((3R)-hydroxymyristoyl ACP dehydrase) CCC13826_1881 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 157163946 Common - anaerobic ribonucleoside-triphosphate reductase activating protein CCC13826_1899 66 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 157164895 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein B CCC13826_1545 87 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 157165534 Common - ATPase, AAA family protein CCC13826_2129 4 COG3334 COG3334, Uncharacterized conserved protein Function unknown 157165529 Pathogen - uracil phosphoribosyltransferase (ump pyrophosphorylase; uprtase) CCC13826_1941 1 None None None 157165729 Pathogen tlpA methyl-accepting chemotaxis protein CCC13826_2099 1 None None None 157165361 Common - hypothetical protein CCC13826_1082 6 None None None 157165198 Common - putative PHP domain CCC13826_1445 39 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 157165426 Pathogen - putative prepilin-type N- cleavage/methylation domain protein CCC13826_1962 1 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 157165658 Pathogen - hypothetical protein CCC13826_0553 1 None None None 157165441 Common - aaa family atpase CCC13826_0280 11 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 157165583 Common aroE shikimate 5-dehydrogenase CCC13826_0229 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 157163999 Common leuB 3-isopropylmalate dehydrogenase CCC13826_0036 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 157164977 Common prfB peptide chain release factor 2 CCC13826_0584 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 157163971 Common - putative undecaprenol kinase CCC13826_1734 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 157164170 Common - hypothetical protein CCC13826_1738 9 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 157165720 Pathogen - hypothetical protein CCC13826_0260 1 None None None 157165482 Common - polysaccharide deacetylase domain protein CCC13826_0340 79 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 157165602 Common - hypothetical protein CCC13826_0778 116 COG2962 RarD, Predicted permeases General function prediction only 157165406 Common - acetyl-coenzyme A carboxylase carboxyl transferase subunit alpha CCC13826_1551 30 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 157165020 Common cysE serine O-acetyltransferase CCC13826_0082 207 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 157165531 Pathogen - histidine biosynthesis bifunctional protein hisIE CCC13826_1896 1 None None None 157165448 Pathogen - hypothetical protein CCC13826_0814 1 None None None 157165427 Common - hypothetical protein CCC13826_1384 4 None None None 157164912 Common - GTP cyclohydrolase-2 (GTP cyclohydrolase II) CCC13826_1035 91 COG1345 FliD, Flagellar capping protein Cell motility and secretion 157164773 Common rplA ribosomal protein L1 CCC13826_0171 236 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 157164152 Pathogen - signal-transduction sensor protein-pas/pac domain CCC13826_0586 1 None None None 157165163 Common - flavoCytochrome c flavin subunit CCC13826_0270 205 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 157165265 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase CCC13826_1155 75 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 157164903 Common - threonine synthase CCC13826_1453 209 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 157165673 Common - putative transcriptional regulator, AraC family CCC13826_0339 17 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 157163992 Pathogen - metal-sulfur cluster biosynthetic enzyme CCC13826_2012 1 None None None 157165754 Common ribE riboflavin synthase, alpha subunit CCC13826_0555 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 157164952 Common - arylsulfotransferase (asst) superfamily CCC13826_0231 10 None None None 157164711 Common - Ser/Thr protein phosphatase family protein CCC13826_0534 81 COG0622 COG0622, Predicted phosphoesterase General function prediction only 157165667 Common moeA putative molybdopterin biosynthesis protein CCC13826_1329 87 COG1295 Rbn, Predicted membrane protein Function unknown 157164416 Common - hypothetical protein CCC13826_1105 5 None None None 157164570 Common lon ATP-dependent protease La CCC13826_1958 227 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 157164626 Common csh crispr-associated protein, Csh2 family CCC13826_1420 54 COG3649 COG3649, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 157164792 Common rpmF ribosomal protein L32 CCC13826_0988 8 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 157164724 Common - methionine import ATP-binding protein MetN CCC13826_1722 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 157165767 Pathogen - hypothetical protein CCC13826_1946 1 None None None 157163978 Common - metal-activated pyridoxal enzyme CCC13826_0957 15 None None None 157164313 Common - thiamine-monophosphate kinase (Thiamine-phosphatekinase) CCC13826_1042 171 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 157165778 Common era GTP-binding protein CCC13826_0596 45 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 157164815 Common - putative 6-pyruvoyl tetrahydrobiopterin synthase (ptps; ptp synthase) CCC13826_1154 25 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 157164499 Common - ABC-transporter ATP-binding protein CCC13826_1239 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 157163931 Common - valyl-tRNA synthetase CCC13826_0077 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 157164267 Common - ribonuclease PH CCC13826_0698 10 COG0795 COG0795, Predicted permeases General function prediction only 157163938 Common - homoserine dehydrogenase (HDH) CCC13826_1144 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 157165302 Pathogen fliP flagellar biosynthesis protein CCC13826_2229 1 None None None 157165211 Pathogen - heat-inducible transcription repressor HrcA CCC13826_0304 1 None None None 157164345 Common rrmJ ribosomal RNA large subunit methyltransferase J CCC13826_2024 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 157165471 Common - radical SAM domain protein CCC13826_1395 145 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 157165762 Common - prophage protein gp49 CCC13826_0806 24 COG4679 COG4679, Phage-related protein Function unknown 157164870 Common dapD tetrahydrodipicolinate N-succinyltransferase CCC13826_0398 206 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 157164769 Common mscL large conductance mechanosensitive channel protein CCC13826_1549 142 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 157164250 Common - hypothetical protein CCC13826_1889 51 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 157165735 Common - phosphoserine aminotransferase, (psat) CCC13826_0520 71 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157165629 Common rplL ribosomal protein L7/L12 CCC13826_0173 209 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 157165358 Common gyrB DNA gyrase, B subunit CCC13826_1850 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 157164259 Common - transcription elongation factor GreA CCC13826_1577 204 COG0782 GreA, Transcription elongation factor Transcription 157164839 Common - response regulator receiver domain protein CCC13826_0722 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157165495 Common rplK ribosomal protein L11 CCC13826_0170 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 157164800 Common - putative ferric receptor CfrA CCC13826_0337 133 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 157164854 Pathogen - OorC subunit of 2-oxoglutarate:acceptor oxidoreductase CCC13826_0038 1 None None None 157164373 Common nifJ pyruvate:ferredoxin (flavodoxin) oxidoreductase CCC13826_1933 117 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 157165541 Common - ATPase CCC13826_1776 20 None None None 157165230 Common ftsZ cell division protein FtsZ CCC13826_1374 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 157165078 Common - glycosyl transferase, group 2 family protein CCC13826_2177 125 COG4261 COG4261, Predicted acyltransferase General function prediction only 157165048 Common - diaminopimelate epimerase (DAP epimerase) CCC13826_2114 43 None None None 157165174 Common - Na+/H+ antiporter family CCC13826_1405 70 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 157164096 Common hisH imidazole glycerol phosphate synthase, glutamine amidotransferase subunit CCC13826_0445 215 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 157164986 Common atpG ATP synthase F1, gamma subunit CCC13826_0916 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 157164976 Common - putative BcpB CCC13826_2283 8 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 157165389 Pathogen - transcription antitermination protein NusG CCC13826_1191 1 None None None 157164247 Common - sporulation initiation inhibitor protein soj CCC13826_0359 230 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 157164115 Common - thioesterase family protein CCC13826_0540 205 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 157164678 Common - putative two-component sensor CCC13826_0385 208 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 157165019 Common purQ phosphoribosylformylglycinamidine synthase I CCC13826_0134 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 157164037 Pathogen - hypothetical protein CCC13826_0557 1 None None None 157164808 Common - hypothetical protein CCC13826_1497 163 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 157164595 Common clpP ATP-dependent Clp protease, proteolytic subunit ClpP CCC13826_1781 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 157165383 Common - Hsp12 variant C CCC13826_0853 191 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 157164085 Common xth exodeoxyribonuclease III CCC13826_1799 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 157165780 Common - polysulfide reductase chain C (Sulfur reductase chain C) CCC13826_0822 48 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 157165300 Common - dUTPase CCC13826_2153 11 None None None 157165687 Pathogen - hypothetical protein CCC13826_0757 1 None None None 157163860 Common - hypothetical protein CCC13826_0823 45 None None None 157164074 Common thrB homoserine kinase CCC13826_1493 119 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 157165286 Common pckA phosphoenolpyruvate carboxykinase (ATP) CCC13826_1509 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 157164618 Pathogen - hypothetical protein CCC13826_1845 1 None None None 157164919 Common tlpA methyl-accepting chemotaxis protein CCC13826_1993 175 COG0218 COG0218, Predicted GTPase General function prediction only 157164966 Common rplI ribosomal protein L9 CCC13826_1220 200 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 157164308 Common - hypothetical protein CCC13826_1419 4 None None None 157164788 Common - lipoprotein CCC13826_1129 21 COG4380 COG4380, Uncharacterized protein conserved in bacteria Function unknown 157165716 Pathogen - putative integral membrane protein CCC13826_2106 1 None None None 157164091 Pathogen - hypothetical protein CCC13826_0030 3 None None None 157165106 Common - hypothetical protein CCC13826_1624 10 COG1847 Jag, Predicted RNA-binding protein General function prediction only 157164005 Common dnaX DNA polymerase III gamma and tau subunits CCC13826_0369 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 157165391 Common - tetrapyrrole methylase family protein CCC13826_1389 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 157164890 Pathogen - hypothetical protein CCC13826_1942 1 COG1439 COG1439, Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module General function prediction only 157165188 Common - glycosyl transferase, group 2 family protein CCC13826_0472 136 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 157164656 Common - hypothetical protein CCC13826_0258 1 None None None 157164301 Common - putative Myb2 protein CCC13826_2031 191 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 157165374 Common - DNA primase CCC13826_0649 81 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 157165112 Common - phenylalanyl-tRNA synthetase beta chain (Phenylalanine--tRNA ligase beta chain; PheRS) CCC13826_0484 226 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 157165706 Common argS arginyl-tRNA synthetase CCC13826_0543 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 157165590 Common - hypothetical protein CCC13826_1002 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 157164129 Common yyaQ conserved protein YyaQ CCC13826_1913 180 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 157164576 Common - DJ-1 family protein CCC13826_0481 141 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 157165451 Common - 4Fe-4S ferredoxin, iron-sulfur binding CCC13826_0864 34 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 157165080 Pathogen dhs 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase CCC13826_1173 2 None None None 157165483 Common selB selenocysteine-specific elongation factor SelB CCC13826_0687 98 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 157165771 Common - hypothetical protein CCC13826_1661 3 None None None 157165151 Common - hdod domain superfamily CCC13826_2001 51 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 157164195 Common secF protein-export membrane protein SecF CCC13826_0072 219 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 157165376 Common flgH flagellar L-ring protein FlgH CCC13826_0102 99 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 157165010 Common - spore coat polysaccharide biosynthesis protein spsC homolog CCC13826_0299 13 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 157164631 Pathogen - abc transporter, ATP-binding protein CCC13826_1117 1 None None None 157165600 Common - lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase CCC13826_0471 109 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 157163855 Common - hypothetical protein CCC13826_0998 2 None None None 157165346 Common rplW 50S ribosomal protein L23 CCC13826_0788 7 None None None 157165298 Pathogen fixP cytochrome c oxidase, diheme subunit, membrane-bound CCC13826_1472 2 None None None 157164131 Common - 3-dehydroquinate dehydratase (3-dehydroquinase; type iidhqase) CCC13826_0805 29 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 157165741 Pathogen - hypothetical protein CCC13826_1557 1 None None None 157165311 Common - putative permease subfamily CCC13826_0419 124 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 157163883 Common - hypothetical protein CCC13826_1090 10 None None None 157164690 Common - hypothetical protein CCC13826_1136 3 None None None 157165500 Common nusA transcription termination factor NusA CCC13826_0599 219 COG0195 NusA, Transcription elongation factor Transcription 157163890 Common - type VI secretion protein, family CCC13826_1178 45 COG3522 COG3522, Uncharacterized protein conserved in bacteria Function unknown 157164989 Common - hypothetical protein CCC13826_0871 1 None None None 157165457 Common - putative ABC transporter, ATP-binding protein CCC13826_1928 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 157165647 Common - trigger factor (TF) CCC13826_2176 61 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 157165290 Common - phosphoglycerate mutase family protein CCC13826_1261 53 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 157165235 Common - RNA pseudouridine synthase family CCC13826_1435 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 157164687 Common - extracellular solute-binding protein, family 7 CCC13826_1324 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 157164343 Common - twitching motility protein CCC13826_1584 219 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 157165127 Common - general stress protein 14 (GSP14) CCC13826_2303 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 157164257 Common infC translation initiation factor IF-3 CCC13826_1818 210 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 157165562 Common - tetratricopeptide repeat domain protein CCC13826_0145 36 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 157164007 Common - NADH dehydrogenase superfamily CCC13826_1663 179 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 157164437 Common cas crispr-associated helicase Cas3 domain protein CCC13826_1422 88 COG1203 COG1203, Predicted helicases General function prediction only 157164955 Pathogen - serine hydroxymethyltransferase (serine methylase; shmt) CCC13826_1692 1 None None None 157164833 Common eno phosphopyruvate hydratase CCC13826_2093 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 157164357 Pathogen trxB thioredoxin reductase CCC13826_1172 2 None None None 157165694 Common - hypothetical protein CCC13826_1621 4 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 157165654 Common - hypothetical protein CCC13826_1098 13 COG4872 COG4872, Predicted membrane protein Function unknown 157165281 Common - competence/damage-inducible domain protein CCC13826_0718 11 COG2952 COG2952, Uncharacterized protein conserved in bacteria Function unknown 157164288 Common ftsY signal recognition particle-docking protein FtsY CCC13826_1312 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 157164607 Common - hypothetical protein CCC13826_0050 2 None None None 157165135 Common - ComEC/Rec2 family protein CCC13826_0888 124 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 157165723 Common mpr ATP-binding protein CCC13826_0392 32 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 157165329 Common - putative ABC transporter, permease protein CCC13826_1249 115 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 157165446 Pathogen hydB quinone-reactive Ni/Fe hydrogenase, large subunit CCC13826_1125 1 None None None 157164932 Common - putative GlnD family protein CCC13826_0405 67 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 157164233 Common - dihydroorotate dehydrogenase CCC13826_1143 40 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 157164467 Common algC phosphomannomutase CCC13826_0872 85 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 157165031 Pathogen - aspartokinase (Aspartate kinase) CCC13826_0334 1 None None None 157164536 Common - hydrogenase maturation protease HydD CCC13826_0098 59 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 157164665 Common - hypothetical protein CCC13826_2200 62 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 157164879 Pathogen - hypothetical protein CCC13826_0936 1 None None None 157165027 Common - hypothetical protein CCC13826_1528 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 157164582 Common ilvA threonine dehydratase CCC13826_1403 215 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 157165276 Common - transcription elongation factor GreA (Transcript cleavage factorgreA) CCC13826_0497 178 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 157165129 Common - GTP-binding protein EngA CCC13826_0777 235 COG1160 COG1160, Predicted GTPases General function prediction only 157165524 Common tkt transketolase CCC13826_1735 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 157165501 Pathogen gdhA glutamate dehydrogenase, NADP-specific CCC13826_2140 1 None None None 157163981 Common - hypothetical protein CCC13826_1961 7 None None None 157164942 Common - peptide chain release factor 2 (RF-2) CCC13826_1574 80 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 157165613 Common - thioesterase family protein CCC13826_2146 115 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 157164449 Common - transglycosylase SLT domain protein CCC13826_1546 102 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 157164565 Common gmk guanylate kinase CCC13826_0545 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 157165143 Pathogen - hypothetical protein CCC13826_1328 1 None None None 157164550 Common glnQ glutamine ABC transporter, ATP-binding protein CCC13826_0869 146 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 157163901 Common - hypothetical protein CCC13826_0976 5 None None None 157165642 Pathogen - hypothetical protein CCC13826_1683 1 None None None 157165578 Common - peptidase E CCC13826_1263 113 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 157165005 Common - putative flagella basal body P-ring formation protein FlgA CCC13826_1268 5 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 157165701 Common sodB superoxide dismutase CCC13826_0763 48 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 157163988 Pathogen - hypothetical protein CCC13826_2054 1 None None None 157164225 Common - FlhB domain protein CCC13826_1080 5 COG1289 COG1289, Predicted membrane protein Function unknown 157164523 Common - putative outer membrane protein CCC13826_0601 1 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 157165438 Common - methyl-accepting chemotaxis protein CCC13826_2196 145 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 157164175 Common pcm protein-L-isoaspartate O-methyltransferase CCC13826_0294 153 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 157165632 Common pyrB aspartate carbamoyltransferase CCC13826_2039 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 157164189 Common - S-layer homology domain ribonuclease CCC13826_0239 10 COG4290 COG4290, Guanyl-specific ribonuclease Sa Nucleotide transport and metabolism 157164213 Common - iron compounds ABC transporter, ATP-binding protein CCC13826_0451 203 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157164638 Common - DNA polymerase III delta prime subunit HolB CCC13826_0332 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 157165244 Pathogen - hypothetical protein CCC13826_0401 1 None None None 157164869 Common - endoribonuclease L-PSP superfamily CCC13826_1452 175 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 157164862 Common - carbamoyl-phosphate synthase large chain (Carbamoyl-phosphate synthetase ammonia chain) CCC13826_0741 165 None None None 157164476 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase CCC13826_1566 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 157164813 Common acpP acyl carrier protein CCC13826_1553 95 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 157164367 Common - 5,10-methenyltetrahydrofolate synthetase CCC13826_1310 32 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 157164277 Common gap glyceraldehyde-3-phosphate dehydrogenase, type I CCC13826_0516 228 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 157165109 Common - L-asparaginase, type II subfamily CCC13826_0029 132 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 157165218 Common - ABC transporter, permease protein CCC13826_0203 178 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 157164921 Common yihK GTP-binding protein CCC13826_1307 117 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 157165217 Pathogen - flagellar biosynthesis protein FlhA CCC13826_0313 1 COG3311 AlpA, Predicted transcriptional regulator Transcription 157164646 Pathogen - metallo-beta-lactamase family protein CCC13826_0301 1 None None None 157164556 Common - nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase CCC13826_0295 26 COG0388 COG0388, Predicted amidohydrolase General function prediction only 157165624 Common - putative ATP synthase F0, C subunit CCC13826_1502 35 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 157164041 Common - glutamyl-tRNA synthetase (Glutamate--tRNA ligase; GluRS) CCC13826_0468 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 157164703 Common - LemA family CCC13826_2159 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 157164047 Common - sensory box/ggdef domain/hd domain protein CCC13826_1102 2 None None None 157165353 Common - quinol dehydrogenase periplasmic component CCC13826_0867 66 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 157164462 Common hsdM type I restriction-modification system, M subunit CCC13826_1412 161 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 157165266 Common - hypothetical protein CCC13826_1149 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 157164380 Common - helix-turn-helix domain protein CCC13826_0807 20 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 157164117 Common hypD hydrogenase expression/formation protein HypD CCC13826_1094 108 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 157163966 Common - addiction module toxin, RelE/StbE family CCC13826_1860 30 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 157165418 Common mgtE magnesium transporter CCC13826_1332 169 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 157165007 Common - hypothetical protein CCC13826_0089 1 None None None 157164559 Common - type IV pilus assembly protein PilZ CCC13826_0984 3 None None None 157165222 Common recJ single-stranded-DNA-specific exonuclease RecJ CCC13826_0910 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 157165668 Common - Cys/Met metabolism PLP-dependent enzyme superfamily CCC13826_0324 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 157164134 Common lpxB lipid A disaccharide synthase CCC13826_0496 77 COG4121 COG4121, Uncharacterized conserved protein Function unknown 157164547 Common - mercuric transport protein periplasmic component CCC13826_2066 38 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 157164362 Common psd phosphatidylserine decarboxylase CCC13826_0440 15 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 157164017 Common - glycosyl transferase, group 1 family protein CCC13826_0455 205 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157164394 Common sppA signal peptide peptidase SppA, 36K type CCC13826_0373 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 157165463 Common def peptide deformylase CCC13826_1783 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 157164067 Common - N-carbamoyl-L-amino acid hydrolase (L-carbamoylase) CCC13826_0648 131 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 157164140 Common gerC gerC2 protein CCC13826_0518 202 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 157165734 Common purN phosphoribosylglycinamide formyltransferase CCC13826_1786 217 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 157164202 Common - hypothetical protein CCC13826_1043 3 None None None 157164149 Pathogen - hypothetical protein CCC13826_0183 1 None None None 157165697 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase CCC13826_0420 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 157165355 Common - hypothetical protein CCC13826_1055 4 None None None 157164738 Common - cyclic diguanylate phosphodiesterase (EAL) domain protein CCC13826_0247 161 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 157165665 Common - outer-membrane lipoprotein carrier protein CCC13826_1073 7 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 157164187 Common - mosc domain protein CCC13826_1855 79 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 157164318 Pathogen - molybdopterin converting factor, subunit 2 CCC13826_1859 1 None None None 157164901 Pathogen - bifunctional DNA-directed RNA polymerase, beta and beta' chain CCC13826_1196 1 None None None 157164816 Common - surface antigen, CjaA CCC13826_0664 165 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 157165727 Pathogen - hypothetical protein CCC13826_1418 1 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 157164377 Common - probable addiction module antidote protein CCC13826_1201 34 COG3636 COG3636, Predicted transcriptional regulator Transcription 157164143 Pathogen - recombination protein RecR CCC13826_0024 3 COG1106 COG1106, Predicted ATPases General function prediction only 157165455 Common - hypothetical protein CCC13826_1030 6 None None None 157165609 Common glnA glutamine synthetase, type I CCC13826_1446 227 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 157164265 Common - putative heavy metal translocating P-type ATPase subfamily CCC13826_1450 231 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 157164371 Common - YitW CCC13826_1375 139 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 157164488 Common - hypothetical protein CCC13826_1157 4 None None None 157164311 Common - integral membrane protein-permease component, involved in lipoprotein release CCC13826_0767 113 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 157165161 Common tpiA triose-phosphate isomerase CCC13826_0514 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 157165094 Common - hypothetical protein CCC13826_0249 2 None None None 157165769 Common - hypothetical protein CCC13826_1427 37 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 157164028 Pathogen - ATP-dependent protease La 1 CCC13826_1730 1 None None None 157164794 Common pepT peptidase T CCC13826_0800 62 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 157164572 Common - prophage LambdaSa04, RelB antitoxin family protein CCC13826_1293 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 157165179 Common - hypothetical protein CCC13826_0281 12 COG3866 PelB, Pectate lyase Carbohydrate transport and metabolism 157165489 Common - transaldolase CCC13826_0503 32 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 157165617 Common - NAD dependent epimerase/dehydratase family CCC13826_1406 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 157163887 Common - phosphatidylserine decarboxylase proenzyme CCC13826_0525 11 None None None 157164974 Common - putative two-component sensor CCC13826_2191 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 157165429 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase CCC13826_0132 223 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 157165404 Pathogen - hypothetical protein CCC13826_0909 1 None None None 157164013 Pathogen - putative permease CCC13826_0660 1 None None None 157164154 Common - protein YgiW CCC13826_1979 17 COG3111 COG3111, Uncharacterized conserved protein Function unknown 157164241 Common leuA 2-isopropylmalate synthase CCC13826_0438 215 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 157165368 Common - putative FAD binding domain CCC13826_1643 65 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 157164744 Pathogen - hypothetical protein CCC13826_1176 2 None None None 157165474 Pathogen - hypothetical protein CCC13826_2247 1 None None None 157165213 Common - hypothetical protein CCC13826_1428 46 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 157165569 Common - processing protease CCC13826_0448 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 157165029 Common ilvE branched-chain amino acid aminotransferase CCC13826_2109 212 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 157164908 Common - putative lipoprotein CCC13826_0007 67 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 157165363 Common - FlhB domain protein CCC13826_0839 117 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 157163894 Common - addiction module toxin, Txe/YoeB family CCC13826_1069 53 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 157164519 Pathogen - hypothetical protein CCC13826_1918 1 None None None 157164328 Common - ATP-sulfurylase family protein CCC13826_1465 52 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 157164676 Common ompR response regulator CCC13826_1287 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 157165588 Pathogen - flagellar basal-body rod protein FlgG (Distal rod protein) CCC13826_0127 1 None None None 157165401 Common ruvC crossover junction endodeoxyribonuclease RuvC CCC13826_1854 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 157165528 Common - hypothetical protein CCC13826_1943 1 None None None 157165480 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase CCC13826_2119 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 157165097 Common groL chaperonin GroL CCC13826_0667 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 157164161 Common - N- methylation CCC13826_0410 196 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 157165538 Common luxS S-Ribosylhomocysteinase (LuxS) CCC13826_1857 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 157164500 Common - radical SAM domain protein CCC13826_0406 167 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 157164969 Pathogen - hypothetical protein CCC13826_2006 1 None None None 157165273 Common - CjaC CCC13826_0963 90 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 157164579 Common cysK cysteine synthase A CCC13826_0081 226 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 157164781 Common - ornithine carbamoyltransferase (OTCase) CCC13826_1033 4 None None None 157165511 Common rpsO 30S ribosomal protein S15 CCC13826_0315 112 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 157165041 Common - hypothetical protein CCC13826_1200 18 COG3657 COG3657, Uncharacterized protein conserved in bacteria Function unknown 157165415 Common dcuC DcuC protein CCC13826_0645 176 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 157164056 Common - putative periplasmic protein CCC13826_1056 145 COG0546 Gph, Predicted phosphatases General function prediction only 157164729 Common - 60Kd inner membrane protein CCC13826_1623 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 157165056 Common - protein YhbP CCC13826_2157 18 COG3787 COG3787, Uncharacterized protein conserved in bacteria Function unknown 157164455 Pathogen - hypothetical protein CCC13826_1387 1 None None None 157163994 Pathogen - hypothetical protein CCC13826_0565 1 None None None 157164150 Common rpsR ribosomal protein S18 CCC13826_1996 123 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 157164525 Common gatC glutamyl-tRNA(Gln) amidotransferase, C subunit CCC13826_0221 83 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 157164020 Common - integral membrane protein CCC13826_0666 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 157164960 Common - hypothetical protein CCC13826_2044 47 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 157165229 Common - putative uracil-DNA glycosylase superfamily CCC13826_0542 81 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 157164283 Common cooS carbon-monoxide dehydrogenase, catalytic subunit CCC13826_0236 24 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 157165692 Common - mate efflux family protein CCC13826_0851 5 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 157164654 Common - hypothetical protein CCC13826_1109 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 157164867 Common - pyridine nucleotide-disulphide oxidoreductase CCC13826_0149 212 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 157164443 Common hcp hydroxylamine reductase CCC13826_1540 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 157165309 Common - acyl-[acyl-carrier-protein]--UDP-N-acetylglucosamine O-acyltransferase CCC13826_1880 18 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 157163933 Common - GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase; GMP synthetase) CCC13826_0475 82 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 157165184 Pathogen atoS signal-transducing protein, histidine kinase CCC13826_0947 1 None None None 157164180 Common fixO cytochrome c oxidase, monoheme subunit, membrane-bound CCC13826_1470 39 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 157163910 Common atpC ATP synthase F1, epsilon subunit CCC13826_0918 176 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 157164072 Common cysE serine O-acetyltransferase CCC13826_1773 224 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 157165068 Common rpsS ribosomal protein S19 CCC13826_2325 242 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 157164191 Common - sensor histidine kinase CCC13826_0396 175 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 157163915 Pathogen - hypothetical protein CCC13826_0306 1 None None None 157165288 Pathogen - hypothetical protein CCC13826_2162 1 None None None 157165186 Common - pyrimidine dimer DNA glycosylase CCC13826_0656 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 157164802 Pathogen - hypothetical protein CCC13826_1944 2 None None None 157164757 Common truD tRNA pseudouridine synthase D CCC13826_1041 84 COG0585 COG0585, Uncharacterized conserved protein Function unknown 157164829 Common trmE tRNA modification GTPase TrmE CCC13826_1625 220 COG0486 ThdF, Predicted GTPase General function prediction only 157165398 Common argG argininosuccinate synthase CCC13826_1219 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 157164293 Common - MacA CCC13826_0073 15 None None None 157164722 Common thiD phosphomethylpyrimidine kinase CCC13826_0950 18 None None None 157165685 Pathogen - periplasmic solute binding protein for ABC transport system CCC13826_2163 1 None None None 157165194 Common hemA glutamyl-tRNA reductase CCC13826_1051 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 157165493 Common - putative dna-binding protein II CCC13826_1834 7 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 157164852 Common - thiamine-phosphate pyrophosphorylase CCC13826_0951 44 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 157164830 Common wbpB lipopolysaccharide biosynthesis protein CCC13826_1534 108 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 157164063 Common fabF 3-oxoacyl-[acyl-carrier-protein] synthase 2 CCC13826_0560 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 157164051 Common - tetratricopeptide repeat domain protein CCC13826_1670 5 None None None 157164845 Common - sec-independent translocase CCC13826_2010 11 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 157163869 Common pgi glucose-6-phosphate isomerase CCC13826_0430 210 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 157164776 Common - ProP protein CCC13826_0670 147 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 157164227 Common - protein YieJ CCC13826_1550 155 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 157164660 Pathogen - hypothetical protein CCC13826_1386 1 None None None 157164767 Common - putative RDD family CCC13826_0491 16 COG1714 COG1714, Predicted membrane protein/domain Function unknown 157164431 Common - hypothetical protein CCC13826_1646 6 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 157165071 Common - hypothetical protein CCC13826_0859 1 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 157164035 Common - type I restriction modification DNA specificity domain protein CCC13826_1411 37 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 157164888 Common - bacterial extracellular solute-binding protein, family 3 CCC13826_1926 181 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 157165478 Common - hypothetical protein CCC13826_2171 27 None None None 157165387 Common - hypothetical protein CCC13826_1798 25 None None None 157165381 Common - hypothetical protein CCC13826_0218 4 None None None 157164440 Common - inner membrane symporter YgjU CCC13826_0067 150 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 157164934 Common nhaC Na+/H+ antiporter NhaC CCC13826_0177 60 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 157164396 Common - hypothetical protein CCC13826_1344 2 None None None 157165207 Common ttdA fumarate hydratase CCC13826_0208 183 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 157164460 Common - hypothetical protein CCC13826_0835 7 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 157164897 Pathogen - hypothetical protein CCC13826_1206 1 None None None 157164754 Common - hypothetical protein CCC13826_0593 4 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 157164420 Pathogen - hypothetical protein CCC13826_1168 1 None None None 157164098 Common - mosc CCC13826_2100 99 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 157164755 Common cheB protein-glutamate methylesterase CheB CCC13826_0841 144 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 157165743 Common coaD pantetheine-phosphate adenylyltransferase CCC13826_1270 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 157164165 Common thiE thiamine-phosphate pyrophosphorylase CCC13826_0400 195 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 157165038 Common metN D-methionine ABC transporter, ATP-binding protein CCC13826_0079 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 157165652 Common - NADH-quinone oxidoreductase subunit I (NADH dehydrogenase I subunit I; NDH-1 subunit I) CCC13826_1664 188 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 157165543 Common - hypothetical protein CCC13826_1089 184 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 157164957 Common - Dyp-type peroxidase CCC13826_1400 59 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 157164795 Pathogen - hypothetical protein CCC13826_1817 1 None None None 157165444 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase (Polyprenylp-hydroxybenzoate decarboxylase) CCC13826_1269 153 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 157164980 Pathogen - shikimate dehydrogenase CCC13826_1951 1 None None None 157164235 Common - putative glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase subfamily CCC13826_0969 240 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 157164351 Common fliS flagellar protein FliS CCC13826_1036 57 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 157165670 Common fdhD formate dehydrogenase family accessory protein FdhD CCC13826_0211 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 157165073 Common - 30S ribosomal protein S12 CCC13826_1638 141 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 157165630 Pathogen - hypothetical protein CCC13826_1187 2 None None None 157165599 Common - transporter, major facilitator family CCC13826_0744 182 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 157165431 Common moaC molybdenum cofactor biosynthesis protein C CCC13826_1731 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 157165607 Common - glycosyl hydrolase family 3 N domain protein CCC13826_0154 181 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 157164427 Pathogen - hypothetical protein CCC13826_2222 1 None None None 157165242 Common - molybdopterin oxidoreductase Fe4S4 domain family CCC13826_0201 178 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 157164147 Common - ribose-phosphate pyrophosphokinase CCC13826_1015 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 157164236 Common - carbonate dehydratase CCC13826_0336 149 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 157164465 Pathogen - hypothetical protein CCC13826_0579 1 None None None 157165254 Common hisG ATP phosphoribosyltransferase CCC13826_0216 208 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 157165639 Common - cell shape determining protein, MreB/Mrl family CCC13826_2125 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 157163871 Common fbcH ubiquinol Cytochrome c oxidoreductase, cytochrome b subunit CCC13826_2316 167 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 157165348 Common aspA aspartate ammonia-lyase CCC13826_0826 7 COG2378 COG2378, Predicted transcriptional regulator Transcription 157165089 Common - hypothetical protein CCC13826_0845 2 None None None 157164513 Common rplU 50S ribosomal protein L21 CCC13826_1221 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 157165012 Common - UDP-N-acetylmuramate--L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase) CCC13826_1930 2 None None None 157165413 Common - superoxide dismutase (Fe) CCC13826_0328 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 157165558 Pathogen - hypothetical protein CCC13826_2252 1 None None None 157165708 Pathogen - hypothetical protein CCC13826_1473 1 None None None 157165320 Common - chaperone ClpB 1 CCC13826_0095 234 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 157164193 Common - hypothetical protein CCC13826_0857 35 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 157163896 Common - sensor histidine kinase CCC13826_1062 175 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 157164692 Pathogen - 4-hydroxy-3-methylbut-2-enyl diphosphate reductase CCC13826_0486 1 None None None 157165114 Common hypD hydrogenase expression/formation protein CCC13826_0105 220 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 157165732 Common napA periplasmic nitrate reductase, large subunit CCC13826_0868 179 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 157164410 Pathogen - hypothetical protein CCC13826_2224 1 None None None 157165378 Pathogen - hypothetical protein CCC13826_0312 1 None None None 157165615 Common - adenylosuccinate synthetase (imp--aspartate ligase; adss; ampsase) CCC13826_1872 76 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 157164561 Common - type VI secretion protein, family CCC13826_1181 50 COG3516 COG3516, Uncharacterized protein conserved in bacteria Function unknown 157164182 Common rpsG ribosomal protein S7 CCC13826_0180 239 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 157164061 Common rseP RIP metalloprotease RseP CCC13826_0124 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 157164298 Common argH argininosuccinate lyase CCC13826_1520 229 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 157165196 Common - R2.LlaJI CCC13826_1629 22 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 157164407 Common - prepilin-type N- cleavage/methylation domain protein CCC13826_1963 4 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 157164597 Pathogen amyH large repetitive protein CCC13826_1837 1 None None None 157165564 Common - amino acid ABC tansporter, permease protein, His/Glu/Gln/Arg/opine family CCC13826_0415 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 157164111 Common - hypothetical protein CCC13826_1707 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 157164045 Common - transport protein CCC13826_2090 220 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 157163862 Pathogen mtrC membrane fusion protein CCC13826_0893 1 None None None 157165645 Common hypE hydrogenase expression/formation protein HypE CCC13826_1093 118 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 157165292 Pathogen - putative phosphonate uptake transporter CCC13826_2278 1 None None None 157164971 Common guaB inosine-5'-monophosphate dehydrogenase CCC13826_0276 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 157165507 Common rplN ribosomal protein L14 CCC13826_1767 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 157165125 Common surE 5'/3'-nucleotidase SurE CCC13826_1575 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 157165756 Common - oxidoreductase, 2-nitropropane dioxygenase family CCC13826_0498 133 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 157164602 Common thyX thymidylate synthase, flavin-dependent CCC13826_1861 40 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 157164860 Common - hypothetical protein CCC13826_1474 16 COG3477 COG3477, Predicted periplasmic/secreted protein Function unknown 157164491 Pathogen - hypothetical protein CCC13826_2165 1 None None None 157164923 Common - peptide methionine sulfoxide reductase family CCC13826_1633 206 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 157164336 Pathogen - integral membrane protein CCC13826_2181 1 None None None 157165679 Common ung uracil-DNA glycosylase CCC13826_1822 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 157165420 Common - ATPase CCC13826_0397 18 None None None 157164369 Common pncB nicotinate phosphoribosyltransferase CCC13826_1903 8 COG0657 Aes, Esterase/lipase Lipid metabolism 157164584 Common - hypothetical protein CCC13826_1262 45 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 157164701 Common - hypothetical protein CCC13826_2314 4 None None None 157164541 Common rpoC DNA-directed RNA polymerase, beta' subunit CCC13826_0175 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 157164353 Common - succinate dehydrogenase flavoprotein subunit CCC13826_1283 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 157164609 Common fliE flagellar hook-basal body complex protein (FliE) CCC13826_0056 41 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 157165626 Pathogen - hypothetical protein CCC13826_0462 1 None None None 157165263 Common flgE flagellar hook protein FlgE CCC13826_1862 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 157165567 Pathogen - hypothetical protein CCC13826_1060 1 None None None 157164705 Common - hypothetical protein CCC13826_2000 192 COG0557 VacB, Exoribonuclease R Transcription 157164205 Common yajC preprotein translocase, YajC subunit CCC13826_0070 168 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 157165773 Common - hypothetical protein CCC13826_2113 25 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 157164326 Pathogen - L-alanyl-D-glutamate peptidase CCC13826_0268 2 None None None 157163964 Common glyS glycyl-tRNA synthetase, beta subunit CCC13826_0043 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 157164644 Common - methyl-accepting chemotaxis sensory transducer CCC13826_1079 193 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 157164502 Common acnB aconitate hydratase 2 CCC13826_1408 223 COG1049 AcnB, Aconitase B Energy production and conversion 157165153 Common - Na+/H+ antiporter CCC13826_1715 107 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 157163958 Pathogen - sugar efflux transporter B CCC13826_1704 1 None None None 157163951 Common - phosphoenolpyruvate carboxykinase (ATP) CCC13826_0428 132 COG1739 COG1739, Uncharacterized conserved protein Function unknown 157165117 Common - biotin synthase (Biotin synthetase) CCC13826_2293 171 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 157165224 Pathogen - hypothetical protein CCC13826_0198 1 None None None 157164731 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase CCC13826_1161 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 157164204 Common - response regulator receiver domain protein CCC13826_0389 181 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 157164173 Common - general stress protein 14 (GSP14) CCC13826_1907 74 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 157164567 Common - histidinol-phosphate aminotransferase (Imidazole acetol-phosphate transaminase) CCC13826_0511 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 157164877 Common - hypothetical protein CCC13826_1668 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 157164534 Pathogen - 2-dehydro-3-deoxyphosphooctonate aldolase CCC13826_0665 1 None None None 157164928 Common selD selenide, water dikinase CCC13826_2135 101 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 157165596 Common - 6,7-dimethyl-8-ribityllumazine synthase CCC13826_0661 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 157165136 Common - nitrous oxidase accessory protein CCC13826_1727 53 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 157164363 Common thrC threonine synthase CCC13826_2052 130 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 157164683 Common - hypothetical protein CCC13826_1391 2 None None None 157164521 Common - putative YbaK / prolyl-tRNA synthetases associated domain CCC13826_1821 28 COG2606 EbsC, Uncharacterized conserved protein Function unknown 157165141 Common - sodium-dependent transporter CCC13826_0533 35 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 157165522 Common - prolipoprotein diacylglyceryl transferase CCC13826_0979 207 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 157164999 Common - monomeric isocitrate dehydrogenase CCC13826_1088 65 COG2838 Icd, Monomeric isocitrate dehydrogenase Energy production and conversion 157165100 Common - CBS domain protein CCC13826_0212 52 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 157163878 Common nrdB ribonucleoside-diphosphate reductase beta chain CCC13826_0736 228 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 157164552 Common topA DNA topoisomerase I CCC13826_2296 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 157164387 Common rplD ribosomal protein L4/L1 family CCC13826_0354 217 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 157163986 Pathogen - hypothetical protein CCC13826_1190 1 None None None 157165172 Common - hypothetical protein CCC13826_2071 5 None None None 157163857 Common - glycosyl transferase, group 1 family protein CCC13826_0477 213 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 157164917 Pathogen - ABC transporter, ATP-binding protein CCC13826_0580 1 None None None 157164694 Common - hypothetical protein CCC13826_1724 14 COG2863 COG2863, Cytochrome c553 Energy production and conversion 157164785 Common - acyl carrier protein CCC13826_2173 45 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 157165274 Common - carboxypeptidase G2 CCC13826_1337 128 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 157164221 Pathogen - hypothetical protein CCC13826_2255 1 None None None 157163926 Common - 7-alpha-hydroxysteroid dehydrogenase CCC13826_0121 233 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 157165640 Common rplV ribosomal protein L22 CCC13826_2324 183 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 157164382 Common - thioredoxin domain protein CCC13826_0059 6 None None None 157165343 Pathogen - hypothetical protein CCC13826_2263 1 None None None