Ignicoccus hospitalis KIN4/I, complete genome NC_009776 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 156937511 Nonpathogen - hypothetical protein Igni_0718 1 None None None 156937350 Nonpathogen - hypothetical protein Igni_0557 4 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 156937902 Nonpathogen - hypothetical protein Igni_1114 1 COG1695 COG1695, Predicted transcriptional regulators Transcription 156937565 Nonpathogen - hypothetical protein Igni_0772 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 156937702 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Igni_0911 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 156936876 Nonpathogen - hypothetical protein Igni_0081 2 COG5185 HEC1, Protein involved in chromosome segregation, interacts with SMC proteins Cell division and chromosome partitioning 156937919 Common - tRNA methyltransferase complex GCD14 subunit Igni_1131 60 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 156936809 Nonpathogen - transcriptional regulator, ArsR family Igni_0014 2 COG2345 COG2345, Predicted transcriptional regulator Transcription 156937209 Common - glucose-6-phosphate isomerase Igni_0415 17 COG2140 COG2140, Thermophilic glucose-6-phosphate isomerase and related metalloenzymes Carbohydrate transport and metabolism / General function prediction only 156937534 Nonpathogen - hypothetical protein Igni_0741 2 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 156937483 Common - replicative DNA polymerase I Igni_0690 61 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 156937024 Common - Radical SAM domain protein Igni_0229 175 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 156938191 Common - histidine triad (HIT) protein Igni_1404 110 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 156937611 Common - putative RNA methylase Igni_0818 127 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 156937679 Common - Ion transport 2 domain protein Igni_0886 10 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 156936960 Common - phosphoribosylamine--glycine ligase Igni_0165 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 156937252 Common - anaerobic ribonucleoside-triphosphate reductase activating protein Igni_0458 63 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 156938066 Nonpathogen - LSU ribosomal protein L32E Igni_1279 34 COG1717 RPL32, Ribosomal protein L32E Translation, ribosomal structure and biogenesis 156938215 Nonpathogen - hypothetical protein Igni_1428 1 None None None 156937198 Nonpathogen - hypothetical protein Igni_0404 1 None None None 156937621 Nonpathogen - transcriptional regulator containing an HTH domain fused to a Zn-ribbon-like protein Igni_0828 21 COG3357 COG3357, Predicted transcriptional regulator containing an HTH domain fused to a Zn-ribbon Transcription 156936995 Nonpathogen - hypothetical protein Igni_0200 1 None None None 156937097 Common - ACT domain-containing protein Igni_0303 42 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 156937314 Common - acetylornithine deacetylase or succinyl-diaminopimelate desuccinylase Igni_0521 203 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 156937715 Common - putative rRNA pseudouridine synthase Igni_0924 242 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 156937050 Common - UspA domain protein Igni_0255 48 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 156937267 Nonpathogen - hypothetical protein Igni_0473 1 None None None 156936929 Nonpathogen - hypothetical protein Igni_0134 1 None None None 156937750 Common - Radical SAM domain protein Igni_0959 60 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 156938131 Nonpathogen - peptide chain release factor subunit 1 (aeRF-1) Igni_1344 34 COG1503 eRF1, Peptide chain release factor 1 (eRF1) Translation, ribosomal structure and biogenesis 156937866 Common - 2-oxoglutarate ferredoxin oxidoreductase, alpha subunit Igni_1078 106 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 156937735 Common - N2-acetyl-L-lysine aminotransferase Igni_0944 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 156937743 Nonpathogen - protein of unknown function DUF125, transmembrane Igni_0952 3 None None None 156937724 Nonpathogen - hypothetical protein Igni_0933 1 COG1634 COG1634, Uncharacterized Rossmann fold enzyme General function prediction only 156937312 Common - translation initiation factor 2B subunit I family (IF-2BI) Igni_0519 132 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 156937924 Nonpathogen - metal dependent phosphohydrolase Igni_1136 1 COG2254 COG2254, Predicted HD superfamily hydrolase, possibly a nuclease DNA replication, recombination, and repair 156938053 Nonpathogen - hypothetical protein Igni_1266 1 None None None 156938225 Nonpathogen - hypothetical protein Igni_1438 5 None None None 156937931 Nonpathogen - serine protease-like protein Igni_1143 6 COG1750 COG1750, Archaeal serine proteases General function prediction only 156937300 Common - PP-loop domain protein Igni_0506 44 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 156937231 Common - hypothetical protein Igni_0437 40 COG4913 COG4913, Uncharacterized protein conserved in bacteria Function unknown 156936969 Nonpathogen - nucleoid protein Alba Igni_0174 28 COG1581 Ssh10b, Archaeal DNA-binding protein Transcription 156937057 Nonpathogen - hypothetical protein Igni_0262 1 None None None 156937897 Common - UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase-like protein Igni_1109 8 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 156937672 Common - histidyl-tRNA synthetase Igni_0879 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156938123 Common - binding-protein-dependent transport systems inner membrane component Igni_1336 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 156938086 Common - replication factor C small subunit Igni_1299 248 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 156937361 Common - glycyl-tRNA synthetase Igni_0568 86 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 156937678 Common - Phosphoglucosamine mutase Igni_0885 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 156938214 Nonpathogen - hypothetical protein Igni_1427 1 None None None 156938118 Common - Fmu (Sun) domain protein Igni_1331 139 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 156937155 Nonpathogen - hypothetical protein Igni_0361 1 None None None 156937151 Nonpathogen - hypothetical protein Igni_0357 1 None None None 156936850 Nonpathogen - hypothetical protein Igni_0055 1 COG2430 COG2430, Uncharacterized conserved protein Function unknown 156937278 Common - phosphotransferase KptA/Tpt1 Igni_0484 41 COG1859 KptA, RNA:NAD 2'-phosphotransferase Translation, ribosomal structure and biogenesis 156937336 Common - NADH-quinone oxidoreductase, B subunit Igni_0543 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 156938164 Common - putative nitrate reductase, subunit H Igni_1377 75 COG0348 NapH, Polyferredoxin Energy production and conversion 156937622 Common - Citrate transporter Igni_0829 76 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 156937947 Common - Nucleotidyl transferase Igni_1159 159 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 156937202 Common - ferredoxin-dependent glutamate synthase Igni_0408 210 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 156937914 Common - hypothetical protein Igni_1126 6 COG3971 COG3971, 2-keto-4-pentenoate hydratase Secondary metabolites biosynthesis, transport, and catabolism 156936930 Nonpathogen - hypothetical protein Igni_0135 6 None None None 156936916 Nonpathogen - hypothetical protein Igni_0121 6 None None None 156937594 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Igni_0801 163 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 156936839 Common - aspartate carbamoyltransferase Igni_0044 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 156937302 Nonpathogen - Protein of unknown function DUF1610 Igni_0508 31 COG2888 COG2888, Predicted Zn-ribbon RNA-binding protein with a function in translation Translation, ribosomal structure and biogenesis 156937869 Nonpathogen - Vacuolar H+-transporting two-sector ATPase, F subunit Igni_1081 8 COG1436 NtpG, Archaeal/vacuolar-type H+-ATPase subunit F Energy production and conversion 156937779 Nonpathogen - TATA binding protein of transcription factor TFIID Igni_0989 34 COG2101 SPT15, TATA-box binding protein (TBP), component of TFIID and TFIIIB Transcription 156938042 Nonpathogen - hypothetical protein Igni_1255 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 156937776 Nonpathogen - hypothetical protein Igni_0985 1 None None None 156938032 Common - Nucleotide binding protein, PINc Igni_1245 99 COG1855 COG1855, ATPase (PilT family) General function prediction only 156937349 Nonpathogen - hypothetical protein Igni_0556 1 None None None 156937550 Common - ATPase involved in chromosome partitioning-like protein Igni_0757 235 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 156936840 Nonpathogen - hypothetical protein Igni_0045 2 COG5650 COG5650, Predicted integral membrane protein Function unknown 156936864 Common - protein of unknown function DUF81 Igni_0069 201 COG0730 COG0730, Predicted permeases General function prediction only 156937716 Common - anthranilate synthase, component I Igni_0925 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 156937065 Nonpathogen - SSU ribosomal protein S27AE Igni_0270 11 COG1998 RPS31, Ribosomal protein S27AE Translation, ribosomal structure and biogenesis 156937111 Nonpathogen - GHMP kinase Igni_0317 6 COG1829 COG1829, Predicted archaeal kinase (sugar kinase superfamily) General function prediction only 156937606 Nonpathogen - prefoldin, beta subunit Igni_0813 19 COG1382 GimC, Prefoldin, chaperonin cofactor Posttranslational modification, protein turnover, chaperones 156937213 Nonpathogen - hypothetical protein Igni_0419 2 COG2319 COG2319, FOG: WD40 repeat General function prediction only 156937685 Common - chorismate mutase Igni_0892 83 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 156937230 Common - protein kinase Igni_0436 95 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 156937238 Nonpathogen - putative signal transduction protein with CBS domains Igni_0444 2 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 156936830 Nonpathogen - hypothetical protein Igni_0035 1 None None None 156937805 Nonpathogen - MazG nucleotide pyrophosphohydrolase Igni_1015 13 COG1694 MazG, Predicted pyrophosphatase General function prediction only 156937539 Nonpathogen - hypothetical protein Igni_0746 1 None None None 156937084 Nonpathogen - SSU ribosomal protein S26E Igni_0290 10 COG4830 RPS26B, Ribosomal protein S26 Translation, ribosomal structure and biogenesis 156937394 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Igni_0601 33 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 156937453 Nonpathogen - hypothetical protein Igni_0660 1 None None None 156937299 Nonpathogen - Uncharacterized protein-like protein Igni_0505 23 COG1888 COG1888, Uncharacterized protein conserved in archaea Function unknown 156937596 Nonpathogen - hypothetical protein Igni_0803 1 None None None 156938026 Nonpathogen - hypothetical protein Igni_1239 1 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 156937377 Nonpathogen - hypothetical protein Igni_0584 1 None None None 156938192 Nonpathogen - peptidase A24A, prepilin type IV Igni_1405 7 None None None 156937990 Nonpathogen - transport system permease protein Igni_1203 1 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 156937973 Nonpathogen - hypothetical protein Igni_1185 1 None None None 156937471 Common - fumarase Igni_0678 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 156938074 Common - DEAD/DEAH box helicase domain protein Igni_1287 216 COG1204 COG1204, Superfamily II helicase General function prediction only 156937115 Nonpathogen - hypothetical protein Igni_0321 1 None None None 156936946 Nonpathogen - DNA-directed RNA polymerase, subunit K Igni_0151 29 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 156937370 Nonpathogen - RNA-binding protein (consists of S1 domain and a Zn-ribbon domain)-like protein Igni_0577 23 COG1096 COG1096, Predicted RNA-binding protein (consists of S1 domain and a Zn-ribbon domain) Translation, ribosomal structure and biogenesis 156936993 Common - Radical SAM domain protein Igni_0198 140 COG2100 COG2100, Predicted Fe-S oxidoreductase General function prediction only 156937971 Nonpathogen - Protein of unknown function DUF431 Igni_1183 8 COG2428 COG2428, Uncharacterized conserved protein Function unknown 156937100 Common - putative circadian clock protein, KaiC Igni_0306 103 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 156938223 Common - 3-deoxy-D-arabinoheptulosonate-7-phosphate synthase Igni_1436 188 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 156937572 Nonpathogen - hypothetical protein Igni_0779 1 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 156937139 Common - FAD dependent oxidoreductase Igni_0345 83 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 156937479 Common - S-adenosylmethionine decarboxylase related Igni_0686 69 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 156938038 Nonpathogen - ATP dependent DNA ligase Igni_1251 19 COG1423 COG1423, ATP-dependent DNA ligase, homolog of eukaryotic ligase III DNA replication, recombination, and repair 156938089 Nonpathogen - hypothetical protein Igni_1302 6 None None None 156937666 Common - Nucleotidyl transferase Igni_0873 227 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 156937586 Nonpathogen - LSU ribosomal protein L37AE Igni_0793 31 COG1997 RPL43A, Ribosomal protein L37AE/L43A Translation, ribosomal structure and biogenesis 156937980 Common - metallophosphoesterase Igni_1193 31 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 156937835 Nonpathogen - amidohydrolase Igni_1046 9 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 156938004 Nonpathogen - protein of unknown function DUF190 Igni_1217 1 COG1993 COG1993, Uncharacterized conserved protein Function unknown 156938111 Common - carbon starvation protein CstA Igni_1324 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 156938178 Common - NH(3)-dependent NAD(+) synthetase Igni_1391 232 COG0171 NadE, NAD synthase Coenzyme metabolism 156937125 Common - CTP synthase Igni_0331 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 156937636 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Igni_0843 198 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 156937408 Nonpathogen - exonuclease of the beta-lactamase fold involved in RNA processing-like protein Igni_0615 14 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 156937817 Common - transcriptional regulator, AsnC family Igni_1027 32 COG1522 Lrp, Transcriptional regulators Transcription 156936888 Nonpathogen - hypothetical protein Igni_0093 2 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 156938171 Nonpathogen - hypothetical protein Igni_1384 1 None None None 156936914 Nonpathogen - hypothetical protein Igni_0119 8 None None None 156937507 Nonpathogen - hypothetical protein Igni_0714 4 None None None 156938108 Nonpathogen - hypothetical protein Igni_1321 1 None None None 156937077 Common - GTP-binding protein, HSR1-related Igni_0283 210 COG2262 HflX, GTPases General function prediction only 156937006 Nonpathogen - ribosomal RNA-processing protein RRP4 Igni_0211 24 COG1097 RRP4, RNA-binding protein Rrp4 and related proteins (contain S1 domain and KH domain) Translation, ribosomal structure and biogenesis 156936977 Common - SSU ribosomal protein S11P Igni_0182 192 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 156938162 Nonpathogen - hypothetical protein Igni_1375 1 None None None 156937968 Common - LSU ribosomal protein L11P Igni_1180 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 156937945 Nonpathogen - hypothetical protein Igni_1157 6 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 156937853 Common - isocitrate dehydrogenase (NADP) Igni_1064 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 156936881 Common - succinyl-CoA synthetase (ADP-forming) beta subunit Igni_0086 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 156937381 Common - SSU ribosomal protein S19P Igni_0588 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 156936940 Nonpathogen - DEAD/DEAH box helicase domain protein Igni_0145 23 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 156937736 Nonpathogen - hypothetical protein Igni_0945 1 None None None 156938101 Nonpathogen - hypothetical protein Igni_1314 1 None None None 156937072 Nonpathogen - hypothetical protein Igni_0277 15 None None None 156937761 Common - sulfate adenylyltransferase Igni_0970 64 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 156937460 Nonpathogen - hypothetical protein Igni_0667 1 None None None 156937613 Nonpathogen - MoaD family protein Igni_0820 11 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 156937428 Common - argininosuccinate synthase Igni_0635 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 156937884 Nonpathogen - hypothetical protein Igni_1096 1 None None None 156936950 Common - SNO glutamine amidotransferase Igni_0155 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 156937513 Nonpathogen - Aminoacyl-tRNA hydrolase Igni_0720 34 COG1990 COG1990, Uncharacterized conserved protein Function unknown 156937741 Nonpathogen - hypothetical protein Igni_0950 5 None None None 156937994 Common - isochorismatase hydrolase Igni_1207 168 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 156937997 Common - hypothetical protein Igni_1210 13 COG1340 COG1340, Uncharacterized archaeal coiled-coil protein Function unknown 156937648 Nonpathogen - DNA primase small subunit Igni_0855 29 COG1467 PRI1, Eukaryotic-type DNA primase, catalytic (small) subunit DNA replication, recombination, and repair 156937978 Common - hypothetical protein Igni_1190 11 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 156937294 Nonpathogen - hypothetical protein Igni_0500 1 COG3342 COG3342, Uncharacterized conserved protein Function unknown 156937872 Common - ABC-type Na+ efflux pump permease component-like protein Igni_1084 35 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 156937387 Nonpathogen - hypothetical protein Igni_0594 1 None None None 156937700 Common - peptidase U62, modulator of DNA gyrase Igni_0909 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 156936815 Common - protein of unknown function UPF0047 Igni_0020 137 COG0432 COG0432, Uncharacterized conserved protein Function unknown 156937089 Common - methionine aminopeptidase, type II Igni_0295 179 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 156938188 Common - acetyl-CoA acetyltransferase Igni_1401 183 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 156936896 Nonpathogen - hypothetical protein Igni_0101 7 COG5491 VPS24, Conserved protein implicated in secretion Cell motility and secretion 156937955 Nonpathogen - hypothetical protein Igni_1167 4 COG4072 COG4072, Uncharacterized protein conserved in archaea Function unknown 156937063 Nonpathogen - hypothetical protein Igni_0268 1 None None None 156937605 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Igni_0812 71 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 156937031 Common - TrkA-N domain protein Igni_0236 168 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 156936989 Nonpathogen - protein of unknown function DUF75 Igni_0194 25 COG1938 COG1938, Archaeal enzymes of ATP-grasp superfamily General function prediction only 156937397 Common - beta-lactamase domain protein Igni_0604 181 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 156937688 Common - thermosome Igni_0897 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 156937936 Common - NADH/Ubiquinone/plastoquinone (complex I) Igni_1148 58 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 156937401 Common - ketol-acid reductoisomerase Igni_0608 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 156936908 Nonpathogen - hypothetical protein Igni_0113 1 None None None 156937147 Nonpathogen - hypothetical protein Igni_0353 1 None None None 156938129 Nonpathogen - hypothetical protein Igni_1342 9 COG1356 COG1356, Uncharacterized protein conserved in archaea Function unknown 156937013 Nonpathogen - hypothetical protein Igni_0218 1 None None None 156937328 Nonpathogen - hypothetical protein Igni_0535 1 None None None 156936799 Nonpathogen - tRNA splicing endonuclease Igni_0004 5 COG1676 SEN2, tRNA splicing endonuclease Translation, ribosomal structure and biogenesis 156937144 Nonpathogen - hypothetical protein Igni_0350 1 None None None 156937186 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Igni_0392 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 156937963 Nonpathogen - LSU ribosomal protein LX Igni_1175 5 COG2157 RPL20A, Ribosomal protein L20A (L18A) Translation, ribosomal structure and biogenesis 156937181 Nonpathogen - LSU ribosomal protein L13E Igni_0387 8 COG4352 RPL13, Ribosomal protein L13E Translation, ribosomal structure and biogenesis 156937284 Common - hydrogenase expression/formation protein HypE Igni_0490 204 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 156937225 Common - tryptophan synthase, alpha chain Igni_0431 142 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 156937241 Nonpathogen - hypothetical protein Igni_0447 1 None None None 156937359 Nonpathogen - aspartate/glutamate/uridylate kinase Igni_0566 33 COG1608 COG1608, Predicted archaeal kinase General function prediction only 156937043 Nonpathogen - hypothetical protein Igni_0248 6 COG1259 COG1259, Uncharacterized conserved protein Function unknown 156937499 Common - transcriptional regulator, AsnC family Igni_0706 97 COG1522 Lrp, Transcriptional regulators Transcription 156937008 Nonpathogen - hypothetical protein Igni_0213 21 COG2512 COG2512, Uncharacterized membrane-associated protein/domain Function unknown 156937909 Nonpathogen - hypothetical protein Igni_1121 1 None None None 156938103 Nonpathogen - hypothetical protein Igni_1316 1 None None None 156936869 Common - membrane protein-like protein Igni_0074 7 COG3463 COG3463, Predicted membrane protein Function unknown 156937628 Nonpathogen - hypothetical protein Igni_0835 1 COG1374 NIP7, Protein involved in ribosomal biogenesis, contains PUA domain Translation, ribosomal structure and biogenesis 156937259 Common - lysyl-tRNA synthetase Igni_0465 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 156937292 Nonpathogen - hypothetical protein Igni_0498 2 None None None 156936813 Common - 3-dehydroquinate synthase Igni_0018 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 156937340 Nonpathogen - protein of unknown function DUF120 Igni_0547 34 COG1339 COG1339, Transcriptional regulator of a riboflavin/FAD biosynthetic operon Transcription / Coenzyme metabolism 156937248 Common - Na+/solute symporter Igni_0454 138 COG4147 DhlC, Predicted symporter General function prediction only 156937059 Nonpathogen - hypothetical protein Igni_0264 1 None None None 156937583 Nonpathogen - hypothetical protein Igni_0790 1 None None None 156938151 Common - transcriptional regulator, TetR family Igni_1364 92 COG1309 AcrR, Transcriptional regulator Transcription 156938198 Common - LSU ribosomal protein L5P Igni_1411 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 156936920 Common - Rhomboid family protein Igni_0125 105 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 156938051 Nonpathogen - hypothetical protein Igni_1264 1 COG1603 RPP1, RNase P/RNase MRP subunit p30 Translation, ribosomal structure and biogenesis 156937168 Common - Sec-independent protein translocase TatC Igni_0374 73 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 156938097 Common - protein of unknown function DUF125, transmembrane Igni_1310 30 COG1814 COG1814, Uncharacterized membrane protein Function unknown 156937713 Nonpathogen - hypothetical protein Igni_0922 1 None None None 156937310 Common - DEAD/DEAH box helicase domain protein Igni_0517 188 COG1205 COG1205, Distinct helicase family with a unique C-terminal domain including a metal-binding cysteine cluster General function prediction only 156936853 Nonpathogen - peptidylprolyl isomerase, FKBP-type Igni_0058 33 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 156937022 Common - dihydroorotate oxidase B, catalytic subunit Igni_0227 165 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 156937086 Common - 5-oxoprolinase (ATP-hydrolyzing) Igni_0292 94 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 156937608 Common - glycosyl transferase, family 2 Igni_0815 57 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 156937726 Nonpathogen - hypothetical protein Igni_0935 5 None None None 156938172 Common - SMC domain protein Igni_1385 55 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 156937788 Nonpathogen - diphthamide biosynthesis protein Igni_0998 32 COG1736 DPH2, Diphthamide synthase subunit DPH2 Translation, ribosomal structure and biogenesis 156937264 Common - ABC transporter related Igni_0470 248 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 156936807 Common - protein of unknown function DUF101 Igni_0012 45 COG1371 COG1371, Uncharacterized conserved protein Function unknown 156938125 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Igni_1338 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 156937540 Common - methionine synthase (B12-independent) Igni_0747 153 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 156937102 Common - putative transcriptional regulator, AsnC family Igni_0308 18 COG1522 Lrp, Transcriptional regulators Transcription 156937904 Nonpathogen - Uncharacterized protein-like protein Igni_1116 11 COG4046 COG4046, Uncharacterized protein conserved in archaea Function unknown 156937926 Nonpathogen - hypothetical protein Igni_1138 1 None None None 156937709 Nonpathogen - membrane protein-like protein Igni_0918 5 COG4920 COG4920, Predicted membrane protein Function unknown 156936939 Common - UspA domain protein Igni_0144 58 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 156937352 Common - competence/damage-inducible protein cinA Igni_0559 165 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 156937683 Common - protein of unknown function DUF72 Igni_0890 74 COG1801 COG1801, Uncharacterized conserved protein Function unknown 156937236 Nonpathogen - IMP biosynthesis enzyme PurP-like protein Igni_0442 20 COG1759 COG1759, ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) General function prediction only 156937163 Nonpathogen - GTPase or GTP-binding protein-like protein Igni_0369 16 COG1341 COG1341, Predicted GTPase or GTP-binding protein General function prediction only 156937342 Nonpathogen - hypothetical protein Igni_0549 1 None None None 156937304 Nonpathogen - hypothetical protein Igni_0510 6 None None None 156937577 Nonpathogen - hypothetical protein Igni_0784 1 None None None 156937196 Nonpathogen - glutamyl-tRNA(Gln) amidotransferase, C subunit Igni_0402 1 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 156937976 Nonpathogen - hypothetical protein Igni_1188 10 None None None 156937656 Nonpathogen - SSU ribosomal protein S3AE Igni_0863 34 COG1890 RPS1A, Ribosomal protein S3AE Translation, ribosomal structure and biogenesis 156936987 Common - cation transporter Igni_0192 170 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 156937900 Nonpathogen - hypothetical protein Igni_1112 1 None None None 156937414 Common - N2-acetyl-L-aminoadipate kinase Igni_0621 218 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 156937029 Nonpathogen - hypothetical protein Igni_0234 1 None None None 156937536 Nonpathogen - hypothetical protein Igni_0743 1 None None None 156937250 Common - UspA domain protein Igni_0456 44 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 156937189 Common - intracellular protease, PfpI family Igni_0395 152 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 156937061 Common - putative metalloendopeptidase, glycoprotease family Igni_0266 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 156937432 Nonpathogen - hypothetical protein Igni_0639 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 156937095 Common - phage SPO1 DNA polymerase-related protein Igni_0301 155 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 156936862 Common - ribosomal RNA methyltransferase NOP2 Igni_0067 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 156938167 Nonpathogen - putative nitrate reductase, subunit D Igni_1380 2 None None None 156937552 Nonpathogen - hypothetical protein Igni_0759 3 None None None 156937644 Nonpathogen - hypothetical protein Igni_0851 1 None None None 156937695 Common - THUMP domain protein Igni_0904 23 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 156937113 Common - methyltransferase Igni_0319 40 COG2520 COG2520, Predicted methyltransferase General function prediction only 156937117 Common - translation initiation factor 2 subunit gamma (aeIF-2g) Igni_0323 249 COG5257 GCD11, Translation initiation factor 2, gamma subunit (eIF-2gamma; GTPase) Translation, ribosomal structure and biogenesis 156937203 Nonpathogen - hypothetical protein Igni_0409 1 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 156938040 Nonpathogen - TatD-related deoxyribonuclease Igni_1253 26 COG1831 COG1831, Predicted metal-dependent hydrolase (urease superfamily) General function prediction only 156937767 Common - Metal-dependent hydrolase of the beta-lactamase superfamily II-like protein Igni_0976 44 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 156937392 Nonpathogen - hypothetical protein Igni_0599 1 None None None 156937777 Nonpathogen - HAD-superfamily hydrolase, subfamily IB (PSPase-like) Igni_0986 10 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 156937797 Common - enolase Igni_1007 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 156937481 Nonpathogen - hypothetical protein Igni_0688 1 None None None 156937334 Nonpathogen - hypothetical protein Igni_0541 1 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 156937674 Nonpathogen - hypothetical protein Igni_0881 1 None None None 156938212 Nonpathogen - Ribonuclease P-related Igni_1425 1 COG1369 POP5, RNase P/RNase MRP subunit POP5 Translation, ribosomal structure and biogenesis 156937153 Nonpathogen - hypothetical protein Igni_0359 1 None None None 156937105 Common - phosphoribosylformylglycinamidine cyclo-ligase Igni_0311 224 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 156937563 Nonpathogen - Transcription initiation factor IIB (TFIIB) Igni_0770 15 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 156938116 Common - indole-3-glycerol phosphate synthase Igni_1329 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 156937389 Common - dihydroorotase Igni_0596 206 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 156938180 Common - protein of unknown function RIO1 Igni_1393 61 COG0478 COG0478, RIO-like serine/threonine protein kinase fused to N-terminal HTH domain Signal transduction mechanisms 156936857 Common - replicative DNA polymerase I Igni_0062 67 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 156937792 Common - small GTP-binding protein Igni_1002 180 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 156938207 Nonpathogen - hypothetical protein Igni_1420 1 None None None 156938006 Common - FeS assembly ATPase SufC Igni_1219 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 156937437 Nonpathogen - hypothetical protein Igni_0644 2 None None None 156937799 Common - type II secretion system protein E Igni_1009 221 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 156937729 Common - leucyl-tRNA synthetase Igni_0938 32 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937321 Nonpathogen - Polysulphide reductase, NrfD Igni_0528 19 COG5557 COG5557, Polysulphide reductase Energy production and conversion 156937221 Nonpathogen - zinc finger, SWIM domain protein Igni_0427 1 COG5431 COG5431, Uncharacterized metal-binding protein Function unknown 156936886 Nonpathogen - hypothetical protein Igni_0091 1 None None None 156936913 Common - ABC transporter related Igni_0118 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 156938094 Common - methyltransferase-like protein Igni_1307 17 COG2521 COG2521, Predicted archaeal methyltransferase General function prediction only 156937634 Nonpathogen - Protein of unknown function DUF650, N-terminal domain Igni_0841 32 COG1602 COG1602, Uncharacterized conserved protein Function unknown 156936963 Common - SSU ribosomal protein S6P modification protein Igni_0168 89 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 156937933 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Igni_1145 176 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 156938015 Common - L-glutamine synthetase Igni_1228 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 156936991 Common - alanyl-tRNA synthetase Igni_0196 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937033 Common - hypothetical protein Igni_0238 22 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 156937122 Nonpathogen - hypothetical protein Igni_0328 13 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 156937509 Nonpathogen - hypothetical protein Igni_0716 6 None None None 156938031 Nonpathogen - hypothetical protein Igni_1244 1 None None None 156937851 Common - ERCC4 domain protein Igni_1062 38 COG1948 MUS81, ERCC4-type nuclease DNA replication, recombination, and repair 156937837 Nonpathogen - hypothetical protein Igni_1048 1 None None None 156937554 Nonpathogen - protein of unknown function DUF402 Igni_0761 16 COG2306 COG2306, Uncharacterized conserved protein Function unknown 156937469 Nonpathogen - translation initiation factor 1A (aeIF-1A) Igni_0676 34 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 156937720 Common - Roadblock/LC7 family protein Igni_0929 17 COG2018 COG2018, Uncharacterized distant relative of homeotic protein bithoraxoid General function prediction only 156938200 Common - SSU ribosomal protein S8P Igni_1413 207 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 156937142 Nonpathogen - Sec-independent protein translocase TatA Igni_0348 8 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 156937588 Nonpathogen - hypothetical protein Igni_0795 2 COG2892 COG2892, Uncharacterized protein conserved in archaea Function unknown 156937075 Common - 3-dehydroquinate dehydratase Igni_0280 24 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 156937774 Common - isopropylmalate/citramalate/homocitrate synthase Igni_0983 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 156937205 Nonpathogen - hypothetical protein Igni_0411 1 None None None 156938194 Nonpathogen - SSU ribosomal protein S17P Igni_1407 34 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 156937790 Nonpathogen - Protein of unknown function DUF207 Igni_1000 14 COG1590 COG1590, Uncharacterized conserved protein Function unknown 156937070 Nonpathogen - hypothetical protein Igni_0275 1 None None None 156937543 Nonpathogen - hypothetical protein Igni_0750 1 COG1693 COG1693, Uncharacterized protein conserved in archaea Function unknown 156936948 Common - peptidase S26B, signal peptidase Igni_0153 29 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 156937818 Nonpathogen - hypothetical protein Igni_1028 2 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 156938072 Nonpathogen - hypothetical protein Igni_1285 1 None None None 156938135 Nonpathogen - Desulfoferrodoxin, ferrous iron-binding region Igni_1348 22 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 156937219 Common - geranylgeranylglyceryl phosphate synthase Igni_0425 26 COG1646 COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold General function prediction only 156938060 Common - phosphoesterase, PA-phosphatase related Igni_1273 17 None None None 156937808 Nonpathogen - Methylase of polypeptide chain release factors-like protein Igni_1018 7 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 156937473 Common - V-type ATPase, D subunit Igni_0680 45 COG1394 NtpD, Archaeal/vacuolar-type H+-ATPase subunit D Energy production and conversion 156937228 Nonpathogen - hypothetical protein Igni_0434 1 COG5276 COG5276, Uncharacterized conserved protein Function unknown 156937570 Common - L-fucose isomerase and related protein-like protein Igni_0777 10 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 156937440 Common - TrkA-C domain protein Igni_0647 19 COG3273 COG3273, Uncharacterized conserved protein Function unknown 156937491 Common - Radical SAM domain protein Igni_0698 209 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 156937827 Common - ribonuclease Z Igni_1037 125 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 156938024 Nonpathogen - hypothetical protein Igni_1237 7 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 156937526 Common - uridylate kinase, putative Igni_0733 39 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 156938149 Nonpathogen - hypothetical protein Igni_1362 1 None None None 156937127 Nonpathogen - hypothetical protein Igni_0333 1 None None None 156936804 Common - beta-lactamase domain protein Igni_0009 141 COG1782 COG1782, Predicted metal-dependent RNase, consists of a metallo-beta-lactamase domain and an RNA-binding KH domain General function prediction only 156937581 Common - hexulose-6-phosphate isomerase Igni_0788 141 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 156937961 Nonpathogen - hypothetical protein Igni_1173 1 None None None 156937920 Nonpathogen - CRISPR-associated protein, Csa1 family Igni_1132 9 COG4343 COG4343, Uncharacterized protein conserved in archaea Function unknown 156937395 Nonpathogen - helix-turn-helix domain protein Igni_0602 29 COG1709 COG1709, Predicted transcriptional regulator Transcription 156937367 Nonpathogen - hypothetical protein Igni_0574 1 None None None 156937427 Nonpathogen - metallophosphoesterase Igni_0634 17 None None None 156937786 Nonpathogen - hypothetical protein Igni_0996 7 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 156937989 Common - molybdenum cofactor biosynthesis protein C Igni_1202 196 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 156937938 Common - translation elongation factor 1A (EF-1A/EF-Tu) Igni_1150 249 COG5256 TEF1, Translation elongation factor EF-1alpha (GTPase) Translation, ribosomal structure and biogenesis 156937286 Common - ATPase of the ABC class-like protein Igni_0492 26 COG3044 COG3044, Predicted ATPase of the ABC class General function prediction only 156938049 Common - peptidase M50 Igni_1262 80 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 156937194 Common - adenylosuccinate lyase Igni_0400 241 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 156937843 Nonpathogen - hypothetical protein Igni_1054 1 COG1901 COG1901, Uncharacterized conserved protein Function unknown 156937045 Nonpathogen - ORC complex protein Cdc6/Orc1 Igni_0250 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 156937357 Common - UspA domain protein Igni_0564 167 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 156938144 Nonpathogen - hypothetical protein Igni_1357 1 None None None 156937375 Common - TGS domain protein Igni_0582 206 COG1163 DRG, Predicted GTPase General function prediction only 156937886 Nonpathogen - hypothetical protein Igni_1098 1 None None None 156937462 Nonpathogen - hypothetical protein Igni_0669 1 None None None 156937738 Common - protein of unknown function DUF62 Igni_0947 74 COG1912 COG1912, Uncharacterized conserved protein Function unknown 156936975 Common - SSU ribosomal protein S13P Igni_0180 125 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 156936874 Common - Zn-dependent hydrolase of the beta-lactamase fold-like protein Igni_0079 75 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 156937803 Nonpathogen - SSU ribosomal protein S30E Igni_1013 1 COG4919 COG4919, Ribosomal protein S30 Translation, ribosomal structure and biogenesis 156937731 Nonpathogen - hypothetical protein Igni_0940 2 None None None 156937747 Common - 2,5-diamino-6-(5-phosphoribosylamino)pyrimidin-4(3H)-one reductase Igni_0956 156 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 156936923 Common - multiple antibiotic resistance (MarC)-related protein Igni_0128 145 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 156937449 Nonpathogen - hypothetical protein Igni_0656 1 None None None 156937916 Common - translation initiation factor 5A (eIF-5A) Igni_1128 41 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 156936901 Common - phosphate ABC transporter, ATPase subunit Igni_0106 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 156937870 Nonpathogen - membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase-like protein Igni_1082 8 COG4346 COG4346, Predicted membrane-bound dolichyl-phosphate-mannose-protein mannosyltransferase Posttranslational modification, protein turnover, chaperones 156937999 Common - putative signal transduction protein with CBS domains Igni_1212 151 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 156938080 Common - ammonium transporter Igni_1293 201 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 156937407 Nonpathogen - MgtE integral membrane region Igni_0614 14 COG1824 COG1824, Permease, similar to cation transporters Inorganic ion transport and metabolism 156936952 Nonpathogen - Like-Sm ribonucleoprotein, core Igni_0157 21 COG1958 LSM1, Small nuclear ribonucleoprotein (snRNP) homolog Transcription 156937681 Common - Phosphomethylpyrimidine kinase type-1 Igni_0888 220 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 156938183 Nonpathogen - hypothetical protein Igni_1396 6 None None None 156937943 Common - methionyl-tRNA synthetase Igni_1155 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937217 Nonpathogen - DNA polymerase, beta domain protein region Igni_0423 12 COG2413 COG2413, Predicted nucleotidyltransferase General function prediction only 156937769 Nonpathogen - Like-Sm ribonucleoprotein, core Igni_0978 28 COG1958 LSM1, Small nuclear ribonucleoprotein (snRNP) homolog Transcription 156937459 Nonpathogen - hypothetical protein Igni_0666 1 None None None 156938127 Common - binding-protein-dependent transport systems inner membrane component Igni_1340 180 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 156937697 Common - glutaredoxin-like domain protein Igni_0906 32 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 156938152 Common - GTPase of unknown function-like protein Igni_1365 247 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 156937332 Common - Citrate transporter Igni_0539 74 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 156937923 Nonpathogen - CRISPR-associated protein Cas4 Igni_1135 5 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 156937529 Nonpathogen - hypothetical protein Igni_0736 1 COG1630 COG1630, Uncharacterized protein conserved in archaea Function unknown 156937658 Nonpathogen - hypothetical protein Igni_0865 1 None None None 156937371 Common - ribosomal-protein-alanine acetyltransferase Igni_0578 126 COG0456 RimI, Acetyltransferases General function prediction only 156938114 Nonpathogen - hypothetical protein Igni_1327 6 None None None 156937601 Nonpathogen - hypothetical protein Igni_0808 1 COG5276 COG5276, Uncharacterized conserved protein Function unknown 156938035 Common - 3-isopropylmalate dehydratase, small subunit Igni_1248 161 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 156936835 Common - adenosylhomocysteinase Igni_0040 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 156936924 Common - protein of unknown function DUF699, ATPase putative Igni_0129 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 156937412 Nonpathogen - putative RNA methylase Igni_0619 40 COG1041 COG1041, Predicted DNA modification methylase DNA replication, recombination, and repair 156937857 Common - hypothetical protein Igni_1069 10 COG4634 COG4634, Uncharacterized protein conserved in bacteria Function unknown 156936859 Nonpathogen - hypothetical protein Igni_0064 1 None None None 156936912 Nonpathogen - hypothetical protein Igni_0117 1 None None None 156937016 Common - ATPase-like protein Igni_0221 46 COG0433 COG0433, Predicted ATPase General function prediction only 156937069 Common - phosphoglycerate kinase Igni_0274 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 156937862 Nonpathogen - hypothetical protein Igni_1074 4 None None None 156937307 Nonpathogen - hypothetical protein Igni_0514 1 None None None 156937840 Nonpathogen - hypothetical protein Igni_1051 1 None None None 156938195 Common - LSU ribosomal protein L14P Igni_1408 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 156936844 Nonpathogen - hypothetical protein Igni_0049 3 None None None 156937405 Nonpathogen - hypothetical protein Igni_0612 1 None None None 156937390 Nonpathogen - hypothetical protein Igni_0597 1 None None None 156937568 Common - glycosyl transferase, family 4 Igni_0775 227 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 156937020 Nonpathogen - hypothetical protein Igni_0225 1 None None None 156937692 Nonpathogen - hypothetical protein Igni_0901 3 None None None 156937365 Common - hydrogenase assembly chaperone hypC/hupF Igni_0572 54 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 156937899 Common - hypothetical protein Igni_1111 3 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 156937858 Nonpathogen - hypothetical protein Igni_1070 3 None None None 156937018 Nonpathogen - Xylose isomerase domain protein TIM barrel Igni_0223 19 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 156937906 Nonpathogen - hypothetical protein Igni_1118 1 None None None 156937046 Nonpathogen - hypothetical protein Igni_0251 1 COG1628 COG1628, Uncharacterized conserved protein Function unknown 156936816 Common - Quinolinate phosphoribosyl transferase Igni_0021 116 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 156938010 Nonpathogen - hypothetical protein Igni_1223 1 None None None 156936972 Common - 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino) imidazole-4-carboxamide isomerase Igni_0177 213 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 156937025 Nonpathogen - LSU ribosomal protein L7AE Igni_0230 35 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 156937324 Common - chorismate synthase Igni_0531 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 156938062 Nonpathogen - LSU ribosomal protein L30P Igni_1275 34 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 156936964 Nonpathogen - hypothetical protein Igni_0169 1 None None None 156937711 Common - protein of unknown function UPF0131 Igni_0920 6 COG2105 COG2105, Uncharacterized conserved protein Function unknown 156936949 Nonpathogen - hypothetical protein Igni_0154 1 None None None 156937763 Nonpathogen - hypothetical protein Igni_0972 3 None None None 156936998 Common - methylated-DNA--protein-cysteine methyltransferase Igni_0203 204 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 156937524 Common - ABC transporter related Igni_0731 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 156937675 Nonpathogen - hypothetical protein Igni_0882 1 COG3432 COG3432, Predicted transcriptional regulator Transcription 156937263 Nonpathogen - hypothetical protein Igni_0469 1 None None None 156937496 Common - protein of unknown function DUF77 Igni_0703 18 COG0011 COG0011, Uncharacterized conserved protein Function unknown 156937173 Common - AMP-dependent synthetase and ligase Igni_0379 221 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 156936847 Common - CDP-alcohol phosphatidyltransferase Igni_0052 80 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 156937027 Nonpathogen - hypothetical protein Igni_0232 1 COG1617 COG1617, Uncharacterized conserved protein Function unknown 156937161 Nonpathogen - hypothetical protein Igni_0367 1 None None None 156938067 Common - LSU ribosomal protein L6P Igni_1280 57 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 156937319 Nonpathogen - hypothetical protein Igni_0526 1 None None None 156937285 Nonpathogen - hypothetical protein Igni_0491 1 None None None 156938057 Common - ABC transporter related Igni_1270 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 156937177 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Igni_0383 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 156937632 Common - transcriptional regulator, AsnC family Igni_0839 54 COG1522 Lrp, Transcriptional regulators Transcription 156937754 Common - TBP-interacting protein TIP49 Igni_0963 96 COG1224 TIP49, DNA helicase TIP49, TBP-interacting protein Transcription 156937356 Common - Radical SAM domain protein Igni_0563 99 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 156937739 Common - nicotinamide-nucleotide adenylyltransferase Igni_0948 52 COG1056 NadR, Nicotinamide mononucleotide adenylyltransferase Coenzyme metabolism 156937271 Nonpathogen - hypothetical protein Igni_0477 1 None None None 156937661 Common - Radical SAM domain protein Igni_0868 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 156937256 Nonpathogen - CRISPR-associated RAMP protein, Cmr6 family Igni_0462 7 COG1604 COG1604, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 156937290 Common - methylenetetrahydrofolate reductase Igni_0496 46 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 156937627 Nonpathogen - hypothetical protein Igni_0834 1 None None None 156938221 Nonpathogen - hypothetical protein Igni_1434 1 None None None 156938156 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Igni_1369 76 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 156937615 Common - photosystem I assembly BtpA Igni_0822 41 COG0434 SgcQ, Predicted TIM-barrel enzyme General function prediction only 156936855 Nonpathogen - metallophosphoesterase Igni_0060 9 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 156937706 Common - NUDIX hydrolase Igni_0915 146 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 156937166 Nonpathogen - hypothetical protein Igni_0372 1 None None None 156938147 Common - phosphoadenosine phosphosulfate reductase Igni_1360 77 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 156937053 Nonpathogen - hypothetical protein Igni_0258 1 None None None 156937917 Nonpathogen - hypothetical protein Igni_1129 1 None None None 156937530 Nonpathogen - hypothetical protein Igni_0737 1 None None None 156936982 Nonpathogen - DNA-directed RNA polymerase, subunit N Igni_0187 34 COG1644 RPB10, DNA-directed RNA polymerase, subunit N (RpoN/RPB10) Transcription 156937744 Nonpathogen - nucleic acid binding, OB-fold, tRNA/helicase-type Igni_0953 20 COG1599 RFA1, Single-stranded DNA-binding replication protein A (RPA), large (70 kD) subunit and related ssDNA-binding proteins DNA replication, recombination, and repair 156937464 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Igni_0671 247 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 156937494 Nonpathogen - hypothetical protein Igni_0701 2 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 156937880 Common - Endonuclease IV Igni_1092 51 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 156937489 Common - triosephosphate isomerase Igni_0696 47 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 156937130 Nonpathogen - hypothetical protein Igni_0336 1 None None None 156937480 Nonpathogen - periplasmic solute-binding protein-like protein Igni_0687 1 COG1427 COG1427, Predicted periplasmic solute-binding protein General function prediction only 156936894 Nonpathogen - transcriptional regulator, HxlR family Igni_0099 2 COG1733 COG1733, Predicted transcriptional regulators Transcription 156938008 Nonpathogen - hypothetical protein Igni_1221 9 None None None 156937993 Nonpathogen - Sjogrens syndrome scleroderma autoantigen 1 Igni_1206 11 COG1645 COG1645, Uncharacterized Zn-finger containing protein General function prediction only 156936811 Nonpathogen - Uncharacterized membrane protein required for N-linked glycosylation-like protein Igni_0016 9 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 156937093 Nonpathogen - hypothetical protein Igni_0299 1 None None None 156937825 Nonpathogen - hypothetical protein Igni_1035 1 None None None 156937879 Common - serine hydroxymethyltransferase Igni_1091 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 156937067 Nonpathogen - SSU ribosomal protein S17E Igni_0272 31 COG1383 RPS17A, Ribosomal protein S17E Translation, ribosomal structure and biogenesis 156936902 Common - binding-protein-dependent transport systems inner membrane component Igni_0107 219 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 156937959 Common - beta-lactamase domain protein Igni_1171 59 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 156937369 Nonpathogen - Uncharacterized protein-like protein Igni_0576 8 COG3286 COG3286, Uncharacterized protein conserved in archaea Function unknown 156937950 Nonpathogen - PUA domain containing protein Igni_1162 29 COG1370 COG1370, Prefoldin, molecular chaperone implicated in de novo protein folding, alpha subunit Posttranslational modification, protein turnover, chaperones 156936883 Nonpathogen - hypothetical protein Igni_0088 1 None None None 156938082 Nonpathogen - ORC complex protein Cdc6/Orc1 Igni_1295 31 COG1474 CDC6, Cdc6-related protein, AAA superfamily ATPase DNA replication, recombination, and repair / Posttranslational modification, protein turnover, chaperones 156937380 Common - 26S proteasome subunit P45 family Igni_0587 249 COG1222 RPT1, ATP-dependent 26S proteasome regulatory subunit Posttranslational modification, protein turnover, chaperones 156937915 Nonpathogen - holliday junction resolvase Igni_1127 19 COG1591 COG1591, Holliday junction resolvase - archaeal type DNA replication, recombination, and repair 156937668 Common - protein of unknown function DUF191 Igni_0875 42 COG2107 COG2107, Predicted periplasmic solute-binding protein General function prediction only 156937966 Nonpathogen - protein translocase SEC61 complex, gamma subunit Igni_1178 1 COG2443 Sss1, Preprotein translocase subunit Sss1 Intracellular trafficking and secretion 156937876 Nonpathogen - hypothetical protein Igni_1088 1 None None None 156937422 Nonpathogen - hypothetical protein Igni_0629 1 None None None 156938173 Nonpathogen - hypothetical protein Igni_1386 2 None None None 156938141 Nonpathogen - hypothetical protein Igni_1354 1 None None None 156937518 Common - nucleoside diphosphate kinase Igni_0725 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 156937244 Nonpathogen - hypothetical protein Igni_0450 1 None None None 156937796 Common - DNA repair and recombination protein RadA Igni_1006 243 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 156937865 Common - 2-oxoglutarate ferredoxin oxidoreductase, beta subunit Igni_1077 108 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 156936944 Nonpathogen - hypothetical protein Igni_0149 1 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 156937593 Common - major facilitator superfamily MFS_1 Igni_0800 72 None None None 156936836 Common - PfkB domain protein Igni_0041 147 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 156937295 Nonpathogen - hypothetical protein Igni_0501 1 None None None 156937129 Nonpathogen - hypothetical protein Igni_0335 1 None None None 156937820 Nonpathogen - LamG domain protein jellyroll fold domain protein Igni_1030 2 None None None 156936996 Common - glutamyl-tRNA(Gln) amidotransferase subunit D Igni_0201 136 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 156936796 Common - translation initiation factor aIF-2 Igni_0001 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 156937733 Common - DNA ligase I, ATP-dependent Dnl1 Igni_0942 103 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 156938001 Nonpathogen - hypothetical protein Igni_1214 2 COG1527 NtpC, Archaeal/vacuolar-type H+-ATPase subunit C Energy production and conversion 156936959 Nonpathogen - hypothetical protein Igni_0164 1 None None None 156937557 Nonpathogen - Nucleolar RNA-binding protein Nop10p Igni_0764 21 COG2260 COG2260, Predicted Zn-ribbon RNA-binding protein Translation, ribosomal structure and biogenesis 156937060 Common - protein of unknown function DUF885 Igni_0265 44 COG4805 COG4805, Uncharacterized protein conserved in bacteria Function unknown 156936937 Nonpathogen - hypothetical protein Igni_0142 4 COG1848 COG1848, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 156937104 Nonpathogen - hypothetical protein Igni_0310 1 None None None 156937442 Common - HAD-superfamily hydrolase, subfamily IIA Igni_0649 96 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 156937433 Nonpathogen - protein of unknown function DUF1152 Igni_0640 11 COG4034 COG4034, Uncharacterized protein conserved in archaea Function unknown 156938124 Common - binding-protein-dependent transport systems inner membrane component Igni_1337 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 156938085 Nonpathogen - Protein of unknown function DUF1288 Igni_1298 4 None None None 156937344 Common - UbiD family decarboxylase Igni_0551 146 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 156937135 Common - Phosphoenolpyruvate carboxylase Igni_0341 17 COG1892 COG1892, Uncharacterized protein conserved in archaea Function unknown 156936824 Common - phosphoribosyl-ATP pyrophosphohydrolase Igni_0029 174 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 156938070 Nonpathogen - hypothetical protein Igni_1283 1 None None None 156937360 Nonpathogen - hypothetical protein Igni_0567 4 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 156937810 Nonpathogen - binding-protein-dependent transport systems inner membrane component Igni_1020 1 None None None 156938022 Common - flavin reductase domain protein, FMN-binding protein Igni_1235 24 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 156937542 Common - Methyltransferase type 11 Igni_0749 64 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 156937475 Nonpathogen - H+-transporting two-sector ATPase, C subunit Igni_0682 1 None None None 156937984 Nonpathogen - LSU ribosomal protein L34E Igni_1197 17 COG2174 RPL34A, Ribosomal protein L34E Translation, ribosomal structure and biogenesis 156937574 Nonpathogen - hypothetical protein Igni_0781 1 None None None 156938096 Nonpathogen - hypothetical protein Igni_1309 1 None None None 156938209 Common - thymidylate synthase, flavin-dependent Igni_1422 38 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 156938013 Common - phenylalanyl-tRNA synthetase beta subunit Igni_1226 206 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 156936801 Nonpathogen - hypothetical protein Igni_0006 1 None None None 156937759 Common - adenylylsulfate kinase Igni_0968 146 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 156937935 Nonpathogen - hypothetical protein Igni_1147 1 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 156938104 Common - t-RNA-binding domain protein Igni_1317 19 COG2517 COG2517, Predicted RNA-binding protein containing a C-terminal EMAP domain General function prediction only 156936860 Common - SSU ribosomal protein S10P Igni_0065 245 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 156937454 Nonpathogen - nucleic acid-binding protein consists of a PIN domain and a Zn-ribbon module-like protein Igni_0661 21 COG1439 COG1439, Predicted nucleic acid-binding protein, consists of a PIN domain and a Zn-ribbon module General function prediction only 156937831 Nonpathogen - Uncharacterized protein-like protein Igni_1042 6 COG5399 COG5399, Uncharacterized protein conserved in archaea Function unknown 156937036 Nonpathogen - RecB-family nuclease-like protein Igni_0241 11 COG4080 COG4080, RecB-family nuclease DNA replication, recombination, and repair 156937239 Common - succinate dehydrogenase subunit B Igni_0445 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 156937504 Nonpathogen - hypothetical protein Igni_0711 1 None None None 156938205 Nonpathogen - hypothetical protein Igni_1418 1 None None None 156937121 Common - CRISPR-associated RAMP protein, Cmr4 family Igni_0327 13 COG1336 COG1336, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 156937076 Nonpathogen - hypothetical protein Igni_0282 1 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 156937425 Common - GTP cyclohydrolase Igni_0632 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 156937839 Nonpathogen - Protein of unknown function DUF207 Igni_1050 16 COG1590 COG1590, Uncharacterized conserved protein Function unknown 156937798 Common - major facilitator superfamily MFS_1 Igni_1008 67 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 156938138 Common - exporter of the RND superfamily-like protein Igni_1351 9 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 156938075 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Igni_1288 226 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 156937584 Nonpathogen - Suppressor Mra1 Igni_0791 18 COG1756 Mra1, Uncharacterized conserved protein Function unknown 156937801 Nonpathogen - type II secretion system protein Igni_1011 18 None None None 156937274 Nonpathogen - S-layer domain-like protein Igni_0480 4 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 156936867 Nonpathogen - metallophosphoesterase Igni_0072 14 None None None 156936828 Common - hypothetical protein Igni_0033 18 COG4933 COG4933, Uncharacterized conserved protein Function unknown 156938166 Common - putative nitrate reductase, subunit A Igni_1379 167 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 156937749 Nonpathogen - Protein of unknown function DUF54 Igni_0958 17 COG1931 COG1931, Uncharacterized protein conserved in archaea Function unknown 156937373 Common - Pyridoxal-5'-phosphate-dependent enzyme, beta subunit Igni_0580 223 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 156937892 Nonpathogen - hypothetical protein Igni_1104 1 None None None 156936872 Common - glutamyl-tRNA(Gln) amidotransferase subunit E Igni_0077 212 COG2511 GatE, Archaeal Glu-tRNAGln amidotransferase subunit E (contains GAD domain) Translation, ribosomal structure and biogenesis 156937309 Common - Reverse gyrase Igni_0516 239 COG1110 COG1110, Reverse gyrase DNA replication, recombination, and repair 156937566 Common - imidazole glycerol phosphate synthase subunit hisF Igni_0773 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 156937757 Common - LSU ribosomal protein L23P Igni_0966 177 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 156938142 Nonpathogen - hypothetical protein Igni_1355 1 None None None 156937269 Common - Coenzyme F390 synthetase-like protein Igni_0475 94 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 156937704 Nonpathogen - hypothetical protein Igni_0913 1 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 156938029 Nonpathogen - hypothetical protein Igni_1242 1 None None None 156936910 Nonpathogen - UBA/THIF-type NAD/FAD binding protein Igni_0115 2 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 156936927 Common - Alcohol dehydrogenase Igni_0132 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 156937158 Common - hypothetical protein Igni_0364 36 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 156938120 Common - histidinol phosphate aminotransferase Igni_1333 226 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 156937618 Common - hydrogenase expression/synthesis, HypA Igni_0825 73 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 156937846 Nonpathogen - hypothetical protein Igni_1057 1 None None None 156937260 Common - anthranilate synthase, component II Igni_0466 237 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 156937718 Common - RNA-metabolising metallo-beta-lactamase Igni_0927 132 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 156937659 Nonpathogen - hypothetical protein Igni_0866 1 None None None 156938185 Nonpathogen - Lysine exporter protein (LYSE/YGGA) Igni_1398 6 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 156937339 Common - proton-translocating NADH-quinone oxidoreductase, chain L Igni_0546 207 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 156937048 Nonpathogen - putative translation factor pelota Igni_0253 34 COG1537 PelA, Predicted RNA-binding proteins General function prediction only 156936970 Nonpathogen - hypothetical protein Igni_0175 6 None None None 156937001 Common - transglutaminase domain protein Igni_0206 75 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 156937908 Nonpathogen - hypothetical protein Igni_1120 1 None None None 156937806 Nonpathogen - hypothetical protein Igni_1016 1 None None None 156936907 Nonpathogen - hypothetical protein Igni_0112 4 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 156937527 Nonpathogen - hypothetical protein Igni_0734 1 None None None 156937730 Nonpathogen - hypothetical protein Igni_0939 1 None None None 156938217 Common - argininosuccinate lyase Igni_1430 217 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 156937784 Common - AAA ATPase, central domain protein Igni_0994 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 156937386 Nonpathogen - hypothetical protein Igni_0593 1 None None None 156938154 Common - nickel-dependent hydrogenase, large subunit Igni_1367 98 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 156937273 Common - protein of unknown function DUF214 Igni_0479 186 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 156936899 Common - thiamine biosynthesis protein ThiC Igni_0104 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 156937402 Common - H(+)-transporting two-sector ATPase Igni_0609 34 COG1269 NtpI, Archaeal/vacuolar-type H+-ATPase subunit I Energy production and conversion 156937330 Nonpathogen - cobalamin (vitamin B12) biosynthesis CbiX protein Igni_0537 15 COG2138 COG2138, Uncharacterized conserved protein Function unknown 156937109 Common - acetylornithine deacetylase Igni_0315 200 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 156936935 Common - Extracellular ligand-binding receptor Igni_0140 124 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 156937456 Nonpathogen - hypothetical protein Igni_0663 1 None None None 156937912 Nonpathogen - Transcription factor TFIIE, alpha subunit Igni_1124 31 COG1675 TFA1, Transcription initiation factor IIE, alpha subunit Transcription 156937670 Common - protein-L-isoaspartate O-methyltransferase Igni_0877 183 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 156937638 Common - phosphoribosylformylglycinamidine synthase I Igni_0845 213 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 156937624 Nonpathogen - CBS domain containing protein Igni_0831 1 None None None 156937254 Common - CRISPR-associated RAMP protein, Cmr4 family Igni_0460 25 COG1336 COG1336, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 156938055 Nonpathogen - translation initiation factor 2 subunit beta (aeIF-2b) Igni_1268 34 COG1601 GCD7, Translation initiation factor 2, beta subunit (eIF-2beta)/eIF-5 N-terminal domain Translation, ribosomal structure and biogenesis 156937288 Common - transcriptional regulator, AsnC family Igni_0494 147 COG1522 Lrp, Transcriptional regulators Transcription 156937410 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Igni_0617 215 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 156937630 Nonpathogen - nucleotidyltransferase-like protein Igni_0837 8 COG4914 COG4914, Predicted nucleotidyltransferase General function prediction only 156938158 Common - agmatinase Igni_1371 138 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 156937485 Nonpathogen - hypothetical protein Igni_0692 1 None None None 156937874 Common - Radical SAM domain protein Igni_1086 83 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 156937604 Nonpathogen - hypothetical protein Igni_0811 1 COG3889 COG3889, Predicted solute binding protein General function prediction only 156937860 Nonpathogen - hypothetical protein Igni_1072 1 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 156937420 Nonpathogen - hypothetical protein Igni_0627 1 None None None 156937175 Common - protein of unknown function DUF6, transmembrane Igni_0381 51 COG2962 RarD, Predicted permeases General function prediction only 156937895 Common - Radical SAM domain protein Igni_1107 101 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 156938019 Nonpathogen - hypothetical protein Igni_1232 1 None None None 156937055 Common - molybdopterin biosynthesis MoaE protein Igni_0260 152 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 156937461 Nonpathogen - hypothetical protein Igni_0668 1 None None None 156938092 Common - H+-transporting two-sector ATPase, alpha/beta subunit, central region Igni_1305 247 COG1155 NtpA, Archaeal/vacuolar-type H+-ATPase subunit A Energy production and conversion 156937752 Common - dihydroxyacid dehydratase Igni_0961 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 156937233 Nonpathogen - hypothetical protein Igni_0439 1 None None None 156937537 Nonpathogen - hypothetical protein Igni_0744 1 None None None 156938079 Nonpathogen - hypothetical protein Igni_1292 1 None None None 156937722 Common - 3-isopropylmalate dehydratase, large subunit Igni_0931 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 156937962 Common - 3-dehydroquinate synthase Igni_1174 119 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 156937354 Common - WD-40 repeat protein Igni_0561 14 COG2319 COG2319, FOG: WD40 repeat General function prediction only 156937941 Common - ribonuclease H Igni_1153 44 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 156937171 Common - Acetyl-CoA acetyltransferase-like protein Igni_0377 89 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 156937185 Common - major facilitator superfamily MFS_1 Igni_0391 131 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 156937579 Nonpathogen - dinucleotide-utilizing enzyme-like protein Igni_0786 5 COG1712 COG1712, Predicted dinucleotide-utilizing enzyme General function prediction only 156937694 Common - phosphodiesterase, MJ0936 family Igni_0903 59 COG0622 COG0622, Predicted phosphoesterase General function prediction only 156937023 Nonpathogen - hypothetical protein Igni_0228 1 None None None 156938069 Nonpathogen - RNA polymerase Rbp10 Igni_1282 2 COG1996 RPC10, DNA-directed RNA polymerase, subunit RPC10 (contains C4-type Zn-finger) Transcription 156938106 Common - CBS domain containing protein Igni_1319 23 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 156937882 Common - putative signal-transduction protein with CBS domains Igni_1094 223 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 156936802 Common - DNA topoisomerase I Igni_0007 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 156936849 Nonpathogen - hypothetical protein Igni_0054 1 None None None 156937384 Nonpathogen - LSU ribosomal protein L29P Igni_0591 6 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 156937532 Nonpathogen - hypothetical protein Igni_0739 1 None None None 156936833 Common - ABC transporter related Igni_0038 249 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 156937522 Common - inner-membrane translocator Igni_0729 141 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 156937501 Nonpathogen - Radical SAM domain protein Igni_0708 30 COG1031 COG1031, Uncharacterized Fe-S oxidoreductase Energy production and conversion 156937765 Nonpathogen - Cupin 2, conserved barrel domain protein Igni_0974 14 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 156936919 Nonpathogen - hypothetical protein Igni_0124 1 None None None 156937081 Nonpathogen - LSU ribosomal protein L31E Igni_0287 28 COG2097 RPL31A, Ribosomal protein L31E Translation, ribosomal structure and biogenesis 156936932 Nonpathogen - hypothetical protein Igni_0137 1 None None None 156937641 Nonpathogen - Ser/Thr protein kinase-like protein Igni_0848 13 COG2112 COG2112, Predicted Ser/Thr protein kinase Signal transduction mechanisms 156937849 Nonpathogen - Protein of unknown function DUF655 Igni_1060 33 COG1491 COG1491, Predicted RNA-binding protein Translation, ribosomal structure and biogenesis 156937652 Common - 2-aminoadipate aminotransferase Igni_0859 230 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 156937545 Common - aspartate semialdehyde dehydrogenase Igni_0752 207 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 156937889 Common - molybdopterin oxidoreductase Igni_1101 166 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 156937964 Nonpathogen - prefoldin, alpha subunit Igni_1176 1 COG1730 GIM5, Predicted prefoldin, molecular chaperone implicated in de novo protein folding Posttranslational modification, protein turnover, chaperones 156937815 Nonpathogen - hypothetical protein Igni_1025 1 None None None 156937929 Nonpathogen - hypothetical protein Igni_1141 2 None None None 156937145 Common - purine or other phosphorylase, family 1 Igni_0351 102 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 156937091 Nonpathogen - protein of unknown function DUF343 Igni_0297 11 COG2835 COG2835, Uncharacterized conserved protein Function unknown 156937419 Nonpathogen - hypothetical protein Igni_0626 5 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 156937789 Nonpathogen - LSU ribosomal protein L10AE Igni_0999 34 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 156938175 Nonpathogen - hypothetical protein Igni_1388 3 COG2441 COG2441, Predicted butyrate kinase Energy production and conversion 156937617 Nonpathogen - hypothetical protein Igni_0824 1 COG2457 COG2457, Uncharacterized conserved protein Function unknown 156937187 Common - protein of unknown function UPF0027 Igni_0393 119 COG1690 RtcB, Uncharacterized conserved protein Function unknown 156937107 Common - Anticodon-binding domain protein Igni_0313 240 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156936979 Nonpathogen - LSU ribosomal protein L18AE Igni_0184 40 COG1727 RPL18A, Ribosomal protein L18E Translation, ribosomal structure and biogenesis 156937782 Common - protein of unknown function DUF52 Igni_0992 72 COG1355 COG1355, Predicted dioxygenase General function prediction only 156937088 Nonpathogen - methyltransferase Igni_0294 30 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 156938168 Nonpathogen - hypothetical protein Igni_1381 1 None None None 156937975 Nonpathogen - NAD-dependent epimerase/dehydratase Igni_1187 3 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 156937487 Nonpathogen - protein of unknown function DUF126 Igni_0694 26 COG1786 COG1786, Uncharacterized conserved protein Function unknown 156937466 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Igni_0673 123 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 156937602 Nonpathogen - hypothetical protein Igni_0809 1 None None None 156937451 Nonpathogen - putative transcriptional regulator, CopG family Igni_0658 6 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 156936904 Nonpathogen - peptidase M50 Igni_0109 28 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 156937337 Nonpathogen - NADH-ubiquinone/plastoquinone oxidoreductase, chain 3 Igni_0544 1 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 156936821 Nonpathogen - hypothetical protein Igni_0026 2 None None None 156937703 Nonpathogen - Queuine tRNA-ribosyltransferase contain PUA domain-like protein Igni_0912 11 COG1549 COG1549, Queuine tRNA-ribosyltransferases, contain PUA domain Translation, ribosomal structure and biogenesis 156937760 Nonpathogen - type I phosphodiesterase/nucleotide pyrophosphatase Igni_0969 23 COG3379 COG3379, Uncharacterized conserved protein Function unknown 156936892 Nonpathogen - protein of unknown function DUF89 Igni_0097 9 COG1578 COG1578, Uncharacterized conserved protein Function unknown 156937995 Common - homoserine kinase Igni_1208 104 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 156937224 Common - hypothetical protein Igni_0430 8 None None None 156938036 Common - homocitrate synthase Igni_1249 221 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 156937957 Common - hypothetical protein Igni_1169 6 None None None 156937725 Common - AAA ATPase, central domain protein Igni_0934 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 156938098 Nonpathogen - hypothetical protein Igni_1311 2 None None None 156937123 Nonpathogen - hypothetical protein Igni_0329 1 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 156937804 Nonpathogen - hypothetical protein Igni_1014 1 None None None 156937833 Common - signal recognition particle subunit FFH/SRP54 (srp54) Igni_1044 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 156937561 Nonpathogen - signal recognition particle, subunit SRP19 (srp19) Igni_0768 22 COG1400 SEC65, Signal recognition particle 19 kDa protein Intracellular trafficking and secretion 156937982 Nonpathogen - hypothetical protein Igni_1195 2 None None None 156937664 Common - Myo-inositol-1-phosphate synthase, GAPDH domain protein Igni_0871 53 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 156938176 Nonpathogen - hypothetical protein Igni_1389 6 None None None 156937079 Nonpathogen - DNA-binding TFAR19-related protein Igni_0285 33 COG2118 COG2118, DNA-binding protein General function prediction only 156938045 Common - pyruvate ferredoxin oxidoreductase, alpha subunit Igni_1258 129 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 156937011 Nonpathogen - hypothetical protein Igni_0216 1 None None None 156937946 Nonpathogen - hypothetical protein Igni_1158 1 None None None 156937828 Nonpathogen - hypothetical protein Igni_1039 2 None None None 156936967 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Igni_0172 35 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 156938136 Common - Aspartate dehydrogenase Igni_1349 49 COG1712 COG1712, Predicted dinucleotide-utilizing enzyme General function prediction only 156937038 Common - DNA-directed RNA polymerase, subunit A' Igni_0243 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 156938020 Nonpathogen - hypothetical protein Igni_1233 1 None None None 156937506 Nonpathogen - DNA polymerase sliding clamp subunit B Igni_0713 20 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 156938091 Nonpathogen - hypothetical protein Igni_1304 1 COG3356 COG3356, Predicted membrane protein Function unknown 156938003 Nonpathogen - hypothetical protein Igni_1216 1 None None None 156937131 Common - Endonuclease V Igni_0337 72 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 156937326 Common - protein of unknown function DUF114 Igni_0533 38 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 156938204 Nonpathogen - rRNA 2'-O-methyltransferase fibrillarin Igni_1417 35 COG1889 NOP1, Fibrillarin-like rRNA methylase Translation, ribosomal structure and biogenesis 156938050 Common - malate dehydrogenase (NAD) Igni_1263 172 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 156937074 Nonpathogen - hypothetical protein Igni_0279 1 None None None 156937276 Nonpathogen - hypothetical protein Igni_0482 1 None None None 156937855 Nonpathogen - protein of unknown function DUF265 Igni_1066 21 COG1618 COG1618, Predicted nucleotide kinase Nucleotide transport and metabolism 156936879 Common - DNA-directed RNA polymerase, subunit E' Igni_0084 45 COG1095 RPB7, DNA-directed RNA polymerase, subunit E' Transcription 156937346 Common - SSU ribosomal protein S18P alanine acetyltransferase Igni_0553 114 COG0456 RimI, Acetyltransferases General function prediction only 156936826 Nonpathogen - hypothetical protein Igni_0031 1 None None None 156937041 Nonpathogen - NusA family KH domain protein Igni_0246 31 COG0195 NusA, Transcription elongation factor Transcription 156937416 Common - UDP-N-acetylglucosamine 2-epimerase Igni_0623 149 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 156937477 Common - hydroxymethylbilane synthase Igni_0684 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 156936822 Nonpathogen - hypothetical protein Igni_0027 4 None None None 156938196 Nonpathogen - LSU ribosomal protein L24P Igni_1409 34 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 156937794 Nonpathogen - hypothetical protein Igni_1004 1 None None None 156936994 Common - aspartate kinase Igni_0199 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 156938161 Common - phosphoglycerate mutase Igni_1374 51 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 156937297 Nonpathogen - hypothetical protein Igni_0503 3 None None None 156937547 Common - ATP phosphoribosyltransferase (homohexameric) Igni_0754 214 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 156937444 Common - DNA-directed RNA polymerase, subunit B' Igni_0651 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 156936955 Common - methyltransferase small Igni_0160 158 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 156937215 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Igni_0421 201 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 156937201 Common - glutamate synthase (NADPH) GltB1 subunit Igni_0407 239 COG0067 GltB, Glutamate synthase domain 1 Amino acid transport and metabolism 156937591 Nonpathogen - hypothetical protein Igni_0798 1 None None None 156937598 Common - imidazoleglycerol-phosphate dehydratase Igni_0805 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 156937559 Nonpathogen - Dephospho-CoA kinase-like protein Igni_0766 34 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 156937812 Nonpathogen - hypothetical protein Igni_1022 5 COG1433 COG1433, Uncharacterized conserved protein Function unknown 156936808 Common - aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B Igni_0013 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 156937823 Nonpathogen - hypothetical protein Igni_1033 1 None None None 156937844 Nonpathogen - hypothetical protein Igni_1055 1 None None None 156937281 Common - Radical SAM domain protein Igni_0487 202 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 156937137 Common - inositol monophosphatase Igni_0343 152 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 156937431 Nonpathogen - hypothetical protein Igni_0638 1 None None None 156936798 Nonpathogen - hypothetical protein Igni_0003 3 None None None 156937438 Common - 2-isopropylmalate synthase Igni_0645 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 156937208 Nonpathogen - NMD3 Igni_0414 32 COG1499 NMD3, NMD protein affecting ribosome stability and mRNA decay Translation, ribosomal structure and biogenesis 156938087 Common - replication factor C large subunit Igni_1300 92 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 156936980 Common - LSU ribosomal protein L13P Igni_0185 75 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 156937580 Common - putative ATP binding protein Igni_0787 44 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 156937154 Common - 5-formyltetrahydrofolate cyclo-ligase Igni_0360 22 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 156937441 Common - putative signal transduction protein with CBS domains Igni_0648 117 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 156937553 Nonpathogen - Protein of unknown function UPF0147 Igni_0760 28 COG1698 COG1698, Uncharacterized protein conserved in archaea Function unknown 156938007 Common - SufBD protein Igni_1220 187 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 156937573 Nonpathogen - hypothetical protein Igni_0780 2 None None None 156937032 Nonpathogen - hypothetical protein Igni_0237 1 None None None 156936820 Common - Aldehyde ferredoxin oxidoreductase Igni_0025 58 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 156937463 Nonpathogen - hypothetical protein Igni_0670 1 None None None 156937826 Common - short-chain dehydrogenase/reductase SDR Igni_1036 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 156938110 Nonpathogen - hypothetical protein Igni_1323 1 None None None 156938187 Common - carbamoyl-phosphate synthase small subunit Igni_1400 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 156937450 Nonpathogen - Diphthine synthase Igni_0657 34 COG1798 DPH5, Diphthamide biosynthesis methyltransferase Translation, ribosomal structure and biogenesis 156937791 Nonpathogen - glyceraldehyde-3-phosphate dehydrogenase Igni_1001 37 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 156937949 Nonpathogen - hypothetical protein Igni_1161 1 None None None 156937516 Nonpathogen - SSU ribosomal protein S28E Igni_0723 33 COG2053 RPS28A, Ribosomal protein S28E/S33 Translation, ribosomal structure and biogenesis 156938027 Nonpathogen - hypothetical protein Igni_1240 2 None None None 156937436 Nonpathogen - hypothetical protein Igni_0643 1 None None None 156938073 Nonpathogen - hypothetical protein Igni_1286 1 None None None 156936992 Nonpathogen - hypothetical protein Igni_0197 1 None None None 156938095 Nonpathogen - hypothetical protein Igni_1308 1 None None None 156937141 Common - tyrosyl-tRNA synthetase Igni_0347 41 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937531 Common - Leucyl aminopeptidase Igni_0738 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 156938109 Nonpathogen - hypothetical protein Igni_1322 1 None None None 156937149 Common - hydrogenase accessory protein HypB Igni_0355 157 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 156936915 Nonpathogen - tRNA intron endonuclease Igni_0120 31 COG1676 SEN2, tRNA splicing endonuclease Translation, ribosomal structure and biogenesis 156937944 Nonpathogen - Conserved protein implicated in secretion-like protein Igni_1156 7 COG5491 VPS24, Conserved protein implicated in secretion Cell motility and secretion 156937005 Nonpathogen - ribosomal RNA-processing protein RRP41/SKI6 Igni_0210 34 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 156937821 Nonpathogen - hypothetical protein Igni_1031 1 None None None 156938030 Nonpathogen - hypothetical protein Igni_1243 1 None None None 156937382 Common - LSU ribosomal protein L22P Igni_0589 70 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 156937852 Nonpathogen - hypothetical protein Igni_1063 1 None None None 156937071 Common - succinate dehydrogenase subunit A Igni_0276 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 156937126 Common - Radical SAM domain protein Igni_0332 53 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 156937991 Common - periplasmic binding protein Igni_1204 64 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 156937665 Common - PhoH family protein Igni_0872 197 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 156937289 Common - orotate phosphoribosyltransferase Igni_0495 136 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 156936851 Common - MscS Mechanosensitive ion channel Igni_0056 227 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 156937520 Nonpathogen - hypothetical protein Igni_0727 1 None None None 156936909 Nonpathogen - hypothetical protein Igni_0114 1 None None None 156938056 Nonpathogen - protein of unknown function DUF214 Igni_1269 1 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 156937983 Nonpathogen - hypothetical protein Igni_1196 3 None None None 156938005 Nonpathogen - hypothetical protein Igni_1218 1 None None None 156937279 Nonpathogen - hypothetical protein Igni_0485 14 COG4021 COG4021, Uncharacterized conserved protein Function unknown 156937960 Common - DEAD/H associated domain protein Igni_1172 184 COG1201 Lhr, Lhr-like helicases General function prediction only 156937478 Nonpathogen - protein of unknown function DUF437 Igni_0685 11 COG2411 COG2411, Uncharacterized conserved protein Function unknown 156937637 Nonpathogen - hypothetical protein Igni_0844 10 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 156937388 Common - Vinylacetyl-CoA Delta-isomerase Igni_0595 46 COG2368 COG2368, Aromatic ring hydroxylase Secondary metabolites biosynthesis, transport, and catabolism 156937701 Common - Creatininase Igni_0910 49 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 156937400 Common - phosphate uptake regulator, PhoU Igni_0607 128 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 156937490 Nonpathogen - Shwachman-Bodian-Diamond syndrome protein Igni_0697 34 COG1500 COG1500, Predicted exosome subunit Translation, ribosomal structure and biogenesis 156937969 Common - LSU ribosomal protein L1P Igni_1181 239 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 156937873 Common - ABC transporter related Igni_1085 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 156937649 Nonpathogen - hypothetical protein Igni_0856 2 None None None 156936890 Nonpathogen - hypothetical protein Igni_0095 29 COG1633 COG1633, Uncharacterized conserved protein Function unknown 156937654 Nonpathogen - hypothetical protein Igni_0861 2 None None None 156937251 Common - 4-hydroxybenzoate polyprenyltransferase, putative Igni_0457 119 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 156938228 Common - beta-ribofuranosylaminobenzene 5'-phosphate synthase family Igni_1441 31 COG1907 COG1907, Predicted archaeal sugar kinases General function prediction only 156936897 Common - protein of unknown function DUF224, cysteine-rich region domain protein Igni_0102 35 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 156937954 Nonpathogen - hypothetical protein Igni_1166 1 None None None 156936928 Common - phosphoadenosine phosphosulfate reductase Igni_0133 25 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 156937834 Nonpathogen - hypothetical protein Igni_1045 1 None None None 156937762 Nonpathogen - hypothetical protein Igni_0971 1 None None None 156936976 Common - SSU ribosomal protein S4P Igni_0181 159 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 156937498 Common - Dehydrogenase (flavoprotein)-like protein Igni_0705 50 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 156936951 Common - Vitamin B6 biosynthesis protein Igni_0156 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 156937885 Common - acetolactate synthase, large subunit Igni_1097 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 156937612 Nonpathogen - hypothetical protein Igni_0819 1 None None None 156937429 Nonpathogen - hypothetical protein Igni_0636 5 COG5551 COG5551, Uncharacterized conserved protein Function unknown 156936938 Nonpathogen - hypothetical protein Igni_0143 1 None None None 156938179 Nonpathogen - Protein of unknown function DUF460 Igni_1392 26 COG2433 COG2433, Uncharacterized conserved protein Function unknown 156937996 Nonpathogen - Protein of unknown function DUF373 Igni_1209 29 COG2237 COG2237, Predicted membrane protein Function unknown 156937293 Nonpathogen - hypothetical protein Igni_0499 3 None None None 156937426 Common - spermine synthase Igni_0633 127 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 156937182 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Igni_0388 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 156937327 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Igni_0534 67 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 156936921 Nonpathogen - hypothetical protein Igni_0126 7 COG1542 COG1542, Uncharacterized conserved protein Function unknown 156936814 Common - ProFAR isomerase family protein Igni_0019 6 COG4043 COG4043, Uncharacterized conserved protein Function unknown 156937040 Nonpathogen - LSU ribosomal protein L30E Igni_0245 28 COG1911 RPL30, Ribosomal protein L30E Translation, ribosomal structure and biogenesis 156938145 Nonpathogen - orotidine 5'-phosphate decarboxylase Igni_1358 28 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 156937814 Nonpathogen - hypothetical protein Igni_1024 1 None None None 156938014 Common - phenylalanyl-tRNA synthetase, alpha subunit Igni_1227 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 156937927 Nonpathogen - CRISPR-associated protein Cas5 Igni_1139 2 COG1688 COG1688, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 156937687 Nonpathogen - hypothetical protein Igni_0896 1 None None None 156937937 Nonpathogen - hypothetical protein Igni_1149 4 COG2112 COG2112, Predicted Ser/Thr protein kinase Signal transduction mechanisms 156936900 Common - protein of unknown function DUF763 Igni_0105 32 COG1415 COG1415, Uncharacterized conserved protein Function unknown 156937470 Nonpathogen - SSU ribosomal protein S6E Igni_0677 34 COG2125 RPS6A, Ribosomal protein S6E (S10) Translation, ribosomal structure and biogenesis 156937398 Nonpathogen - hypothetical protein Igni_0605 1 None None None 156937351 Nonpathogen - hypothetical protein Igni_0558 1 None None None 156938134 Common - DEAD/DEAH box helicase domain protein Igni_1347 241 COG1201 Lhr, Lhr-like helicases General function prediction only 156937845 Common - carbohydrate kinase, YjeF related protein Igni_1056 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 156937505 Nonpathogen - hypothetical protein Igni_0712 1 COG5542 COG5542, Predicted integral membrane protein Function unknown 156938128 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Igni_1341 87 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 156937979 Common - glycerophosphoryl diester phosphodiesterase Igni_1191 99 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 156936832 Nonpathogen - hypothetical protein Igni_0037 1 None None None 156936988 Nonpathogen - SSU ribosomal protein S25E Igni_0193 8 COG4901 COG4901, Ribosomal protein S25 Translation, ribosomal structure and biogenesis 156937610 Nonpathogen - hypothetical protein Igni_0817 8 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 156937502 Common - hypothetical protein Igni_0709 10 COG4997 COG4997, Uncharacterized conserved protein Function unknown 156937184 Nonpathogen - hypothetical protein Igni_0390 1 None None None 156937533 Nonpathogen - hypothetical protein Igni_0740 1 None None None 156937549 Common - cytidylate kinase, putative Igni_0756 75 COG1102 Cmk, Cytidylate kinase Nucleotide transport and metabolism 156938130 Common - nuclease (SNase domain protein) Igni_1343 4 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 156936926 Common - metal dependent phosphohydrolase Igni_0131 15 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 156936812 Nonpathogen - hypothetical protein Igni_0017 3 None None None 156937021 Common - transcriptional regulator, AsnC family Igni_0226 30 COG1522 Lrp, Transcriptional regulators Transcription 156937291 Common - putative signal-transduction protein with CBS domains Igni_0497 87 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 156936933 Nonpathogen - UBA/THIF-type NAD/FAD binding protein Igni_0138 1 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 156937364 Common - 3-octaprenyl-4hydroxybenzoate decarboxylase Igni_0571 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 156936961 Nonpathogen - hypothetical protein Igni_0166 1 None None None 156938063 Common - SSU ribosomal protein S5P Igni_1276 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 156937512 Nonpathogen - hypothetical protein Igni_0719 2 COG4882 COG4882, Predicted aminopeptidase, Iap family General function prediction only 156937197 Nonpathogen - hypothetical protein Igni_0403 1 None None None 156938211 Nonpathogen - hypothetical protein Igni_1424 1 None None None 156937393 Common - amidophosphoribosyltransferase Igni_0600 227 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 156937030 Nonpathogen - hypothetical protein Igni_0235 2 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 156937101 Common - Prephenate dehydratase Igni_0307 214 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 156936957 Common - molybdenum cofactor synthesis domain Igni_0162 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 156938197 Nonpathogen - SSU ribosomal protein S4E Igni_1410 34 COG1471 RPS4A, Ribosomal protein S4E Translation, ribosomal structure and biogenesis 156937751 Common - hybrid cluster protein Igni_0960 76 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 156936806 Common - molybdenum cofactor synthesis domain Igni_0011 189 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 156937619 Common - Radical SAM domain protein Igni_0826 90 COG1964 COG1964, Predicted Fe-S oxidoreductases General function prediction only 156937169 Common - protein of unknown function DUF84 Igni_0375 19 COG1986 COG1986, Uncharacterized conserved protein Function unknown 156936966 Common - glutamine--fructose-6-phosphate transaminase Igni_0171 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 156936877 Nonpathogen - Protein of unknown function DUF359 Igni_0082 31 COG1909 COG1909, Uncharacterized protein conserved in archaea Function unknown 156937193 Nonpathogen - Nucleoside-diphosphate-sugar pyrophosphorylase-like protein Igni_0399 19 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 156938226 Common - molybdopterin-guanine dinucleotide biosynthesis MobB region Igni_1439 6 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 156937696 Nonpathogen - hypothetical protein Igni_0905 9 COG2522 COG2522, Predicted transcriptional regulator General function prediction only 156937930 Nonpathogen - transcriptional regulator, TrmB Igni_1142 1 COG1378 COG1378, Predicted transcriptional regulators Transcription 156937170 Common - putative hydroxymethylglutaryl-CoA synthase Igni_0376 225 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 156937253 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Igni_0459 220 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 156938054 Common - transketolase subunit A Igni_1267 221 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 156937727 Common - 6,7-dimethyl-8-ribityllumazine synthase Igni_0936 204 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 156937677 Nonpathogen - hypothetical protein Igni_0884 1 None None None 156937056 Common - pyruvate carboxyltransferase Igni_0261 196 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 156937896 Common - geranylgeranyl reductase Igni_1108 43 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 156937317 Nonpathogen - hypothetical protein Igni_0524 1 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 156937417 Nonpathogen - hypothetical protein Igni_0624 4 None None None 156937787 Nonpathogen - hypothetical protein Igni_0997 1 None None None 156937179 Nonpathogen - hypothetical protein Igni_0385 1 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 156938017 Nonpathogen - hypothetical protein Igni_1230 1 COG5625 COG5625, Predicted transcription regulator containing HTH domain Transcription 156937098 Common - 3-isopropylmalate dehydratase, small subunit Igni_0304 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 156938119 Nonpathogen - hypothetical protein Igni_1332 1 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 156937740 Common - protein of unknown function DUF59 Igni_0949 87 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 156937305 Nonpathogen - Predicted hydrolase of the metallo-beta-lactamase superfamily Igni_0511 17 COG2248 COG2248, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 156937623 Nonpathogen - hypothetical protein Igni_0830 1 None None None 156937214 Common - succinate dehydrogenase subunit C Igni_0420 50 COG2048 HdrB, Heterodisulfide reductase, subunit B Energy production and conversion 156938165 Common - putative nitrate reductase, subunit G Igni_1378 65 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 156936865 Nonpathogen - rRNA biogenesis protein Nop56/Nop58 Igni_0070 34 COG1498 SIK1, Protein implicated in ribosomal biogenesis, Nop56p homolog Translation, ribosomal structure and biogenesis 156937014 Nonpathogen - AIR synthase related protein domain protein Igni_0219 19 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 156937003 Nonpathogen - hypothetical protein Igni_0208 1 None None None 156937913 Common - DNA-cytosine methyltransferase Igni_1125 114 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 156937768 Common - type III restriction enzyme, res subunit Igni_0977 91 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 156937642 Nonpathogen - tRNA adenylyltransferase Igni_0849 34 COG1746 CCA1, tRNA nucleotidyltransferase (CCA-adding enzyme) Translation, ribosomal structure and biogenesis 156937587 Nonpathogen - ribosomal biogenesis protein, containing Brix domain Igni_0794 14 COG2136 IMP4, Predicted exosome subunit/U3 small nucleolar ribonucleoprotein (snoRNP) component, contains IMP4 domain Translation, ribosomal structure and biogenesis / RNA processing and modification 156937595 Common - molybdopterin oxidoreductase Igni_0802 169 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 156937484 Common - flap endonuclease 1 Igni_0691 53 COG0258 Exo, 5'-3' exonuclease (including N-terminal domain of PolI) DNA replication, recombination, and repair 156937152 Common - protein of unknown function UPF0153 Igni_0358 12 None None None 156937235 Nonpathogen - hypothetical protein Igni_0441 4 None None None 156937508 Common - AAA ATPase Igni_0715 11 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 156937861 Common - CRISPR-associated protein Cas1 Igni_1073 56 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 156937112 Common - HhH-GPD family protein Igni_0318 12 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 156937335 Common - NADH-ubiquinone oxidoreductase, chain 49kDa Igni_0542 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 156937671 Nonpathogen - hypothetical protein Igni_0878 1 None None None 156937686 Nonpathogen - hypothetical protein Igni_0894 1 None None None 156937064 Common - Orotidine 5'-phosphate decarboxylase Igni_0269 58 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 156936870 Nonpathogen - putative transcriptional regulator, CopG family Igni_0075 2 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 156936831 Common - anaerobic ribonucleoside-triphosphate reductase Igni_0036 98 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 156937268 Nonpathogen - hypothetical protein Igni_0474 1 None None None 156937133 Nonpathogen - hypothetical protein Igni_0339 3 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 156938202 Common - protein of unknown function DUF814 Igni_1415 42 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 156937868 Nonpathogen - H+-transporting two-sector ATPase, E subunit Igni_1080 1 COG1390 NtpE, Archaeal/vacuolar-type H+-ATPase subunit E Energy production and conversion 156936846 Common - SAM-dependent methyltransferase Igni_0051 122 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 156937446 Nonpathogen - hypothetical protein Igni_0653 1 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 156937116 Common - Cyclopropane fatty acid synthase-like protein Igni_0322 44 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 156937780 Common - seryl-tRNA synthetase Igni_0990 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 156938033 Common - Amidohydrolase 3 Igni_1246 78 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 156937901 Common - phosphoenolpyruvate synthase Igni_1113 237 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 156937348 Nonpathogen - major facilitator superfamily MFS_1 Igni_0555 4 None None None 156937986 Common - protein translocase subunit secY/sec61 alpha Igni_1199 207 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 156937078 Nonpathogen - SSU ribosomal protein S19E Igni_0284 34 COG2238 RPS19A, Ribosomal protein S19E (S16A) Translation, ribosomal structure and biogenesis 156937227 Nonpathogen - hypothetical protein Igni_0433 1 None None None 156937878 Common - DNA topoisomerase VI, B subunit Igni_1090 34 COG1389 COG1389, DNA topoisomerase VI, subunit B DNA replication, recombination, and repair 156937850 Nonpathogen - Sec61beta Igni_1061 1 COG4023 SBH1, Preprotein translocase subunit Sec61beta Intracellular trafficking and secretion 156937998 Nonpathogen - protein of unknown function, ATP binding Igni_1211 15 COG1100 COG1100, GTPase SAR1 and related small G proteins General function prediction only 156937106 Nonpathogen - hypothetical protein Igni_0312 1 None None None 156937737 Common - L-aspartate aminotransferase Igni_0946 161 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 156937120 Nonpathogen - CRISPR-associated protein DxTHG motif Igni_0326 3 COG1517 COG1517, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 156938100 Nonpathogen - hypothetical protein Igni_1313 1 None None None 156937836 Common - small GTP-binding protein Igni_1047 158 COG1084 COG1084, Predicted GTPase General function prediction only 156937329 Common - NAD(+) kinase Igni_0536 230 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 156937721 Nonpathogen - hypothetical protein Igni_0930 1 None None None 156937802 Nonpathogen - hypothetical protein Igni_1012 1 None None None 156938193 Common - phosphoadenosine phosphosulfate reductase Igni_1406 21 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 156937468 Common - Non-specific serine/threonine protein kinase Igni_0675 65 COG1718 RIO1, Serine/threonine protein kinase involved in cell cycle control Signal transduction mechanisms / Cell division and chromosome partitioning 156936962 Common - Ras superfamily GTP-binding protein YlqF Igni_0167 98 COG1161 COG1161, Predicted GTPases General function prediction only 156936990 Nonpathogen - hypothetical protein Igni_0195 4 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 156937191 Common - Radical SAM domain protein Igni_0397 102 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 156938132 Common - glutamine amidotransferase class-I Igni_1345 241 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 156937890 Common - cystathionine gamma-synthase Igni_1102 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 156937981 Common - Methyltransferase type 11 Igni_1194 79 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 156937988 Common - solute binding protein-like protein Igni_1201 40 COG3889 COG3889, Predicted solute binding protein General function prediction only 156938208 Nonpathogen - hypothetical protein Igni_1421 2 None None None 156937816 Nonpathogen - hypothetical protein Igni_1026 1 None None None 156937424 Common - Deoxyhypusine synthase Igni_0631 62 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 156937443 Nonpathogen - hypothetical protein Igni_0650 1 None None None 156936887 Nonpathogen - DNA-binding protein containing PIN domain-like protein Igni_0092 19 COG1458 COG1458, Predicted DNA-binding protein containing PIN domain General function prediction only 156937571 Nonpathogen - LSU ribosomal protein L21E Igni_0778 30 COG2139 RPL21A, Ribosomal protein L21E Translation, ribosomal structure and biogenesis 156937034 Nonpathogen - hypothetical protein Igni_0239 6 None None None 156937283 Common - Dipeptidyl aminopeptidase/acylaminoacyl-peptidase-like protein Igni_0489 8 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 156937376 Nonpathogen - Dehydrogenase (flavoprotein)-like protein Igni_0583 27 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 156938189 Nonpathogen - hypothetical protein Igni_1402 18 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 156938047 Nonpathogen - tRNA pseudouridine synthase D, TruD Igni_1260 38 COG0585 COG0585, Uncharacterized conserved protein Function unknown 156936941 Common - daunorubicin resistance ABC transporter ATPase subunit Igni_0146 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 156938148 Common - glucokinase Igni_1361 69 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 156937136 Nonpathogen - pseudouridylate synthase-like protein Igni_0342 33 COG1258 COG1258, Predicted pseudouridylate synthase Translation, ribosomal structure and biogenesis 156938068 Common - translation initiation factor 1 (eIF-1/SUI1) Igni_1281 94 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 156937525 Common - ABC transporter related Igni_0732 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 156937434 Common - quinolinate synthetase A Igni_0641 195 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 156937773 Common - 3-isopropylmalate dehydrogenase Igni_0982 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 156937514 Nonpathogen - tRNA (guanine-N1-)-methyltransferase Igni_0721 12 COG2419 COG2419, Uncharacterized conserved protein Function unknown 156937472 Common - Sodium-transporting two-sector ATPase Igni_0679 247 COG1156 NtpB, Archaeal/vacuolar-type H+-ATPase subunit B Energy production and conversion 156936842 Common - cytochrome c assembly protein Igni_0047 180 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 156937589 Nonpathogen - protein of unknown function, ATP binding Igni_0796 15 COG1100 COG1100, GTPase SAR1 and related small G proteins General function prediction only 156937544 Nonpathogen - hypothetical protein Igni_0751 18 COG2106 COG2106, Uncharacterized conserved protein Function unknown 156937204 Common - beta-lactamase domain protein Igni_0410 103 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 156937555 Nonpathogen - hypothetical protein Igni_0762 1 None None None 156937819 Common - Thrombospondin type 3 repeat Igni_1029 37 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 156936947 Nonpathogen - hypothetical protein Igni_0152 1 None None None 156938071 Common - SPP-like hydrolase Igni_1284 82 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 156937465 Nonpathogen - protein of unknown function DUF1641 Igni_0672 3 COG2427 COG2427, Uncharacterized conserved protein Function unknown 156938224 Common - RNase HII Igni_1437 120 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 156937842 Common - DNA topoisomerase (ATP-hydrolyzing) Igni_1053 34 COG1697 COG1697, DNA topoisomerase VI, subunit A DNA replication, recombination, and repair 156937977 Common - Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein Igni_1189 69 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 156937044 Common - SSU ribosomal protein S7P Igni_0249 242 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 156937655 Nonpathogen - hypothetical protein Igni_0862 1 None None None 156937887 Common - histidine triad (HIT) protein Igni_1099 220 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 156938048 Nonpathogen - LSU ribosomal protein L14E Igni_1261 18 COG2163 RPL14A, Ribosomal protein L14E/L6E/L27E Translation, ribosomal structure and biogenesis 156936873 Nonpathogen - DNA primase large subunit Igni_0078 24 COG2219 PRI2, Eukaryotic-type DNA primase, large subunit DNA replication, recombination, and repair 156937519 Nonpathogen - hypothetical protein Igni_0726 1 None None None 156938025 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Igni_1238 19 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 156937062 Nonpathogen - hypothetical protein Igni_0267 1 None None None 156937939 Nonpathogen - hypothetical protein Igni_1151 2 None None None 156937220 Nonpathogen - hypothetical protein Igni_0426 6 COG4888 COG4888, Uncharacterized Zn ribbon-containing protein General function prediction only 156937714 Nonpathogen - Uncharacterized protein-like protein Igni_0923 9 COG4879 COG4879, Uncharacterized protein conserved in archaea Function unknown 156936984 Common - Ferredoxin-like protein Igni_0189 15 COG1141 Fer, Ferredoxin Energy production and conversion 156937859 Nonpathogen - hypothetical protein Igni_1071 1 None None None 156937396 Nonpathogen - Nascent polypeptide associated complex NAC Igni_0603 8 COG1308 EGD2, Transcription factor homologous to NACalpha-BTF3 Transcription 156938012 Nonpathogen - hypothetical protein Igni_1225 1 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 156937226 Nonpathogen - hypothetical protein Igni_0432 1 None None None 156937368 Nonpathogen - DNA-directed RNA polymerase, subunit L Igni_0575 8 COG1761 RPB11, DNA-directed RNA polymerase, subunit L Transcription 156937448 Common - putative signal-transduction protein with CBS domains Igni_0655 153 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 156937708 Nonpathogen - hypothetical protein Igni_0917 1 None None None 156938000 Nonpathogen - hypothetical protein Igni_1213 1 None None None 156937746 Common - hypothetical protein Igni_0955 17 None None None 156937409 Common - Proteasome endopeptidase complex Igni_0616 50 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 156938081 Common - nitrogen regulatory protein P-II Igni_1294 177 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 156937824 Common - L-threonine synthase Igni_1034 117 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 156937247 Nonpathogen - Proteasome endopeptidase complex Igni_0453 34 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 156937406 Nonpathogen - hypothetical protein Igni_0613 1 None None None 156937320 Nonpathogen - hypothetical protein Igni_0527 1 None None None 156937871 Nonpathogen - SNARE associated Golgi protein Igni_1083 5 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 156937645 Nonpathogen - DNA-directed RNA polymerase, subunit M Igni_0852 33 COG1594 RPB9, DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS Transcription 156936818 Nonpathogen - hypothetical protein Igni_0023 1 None None None 156937240 Nonpathogen - hypothetical protein Igni_0446 22 COG1833 COG1833, Uncharacterized conserved protein Function unknown 156936953 Common - Methionine adenosyltransferase Igni_0158 43 COG1812 MetK, Archaeal S-adenosylmethionine synthetase Amino acid transport and metabolism 156938088 Common - tryptophanyl-tRNA synthetase Igni_1301 144 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937921 Common - CRISPR-associated protein Cas1 Igni_1133 98 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 156937492 Nonpathogen - hypothetical protein Igni_0699 1 None None None 156937620 Nonpathogen - hypothetical protein Igni_0827 1 None None None 156936974 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Igni_0179 226 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 156937452 Common - pyrroline-5-carboxylate reductase Igni_0659 163 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 156937249 Nonpathogen - hypothetical protein Igni_0455 1 COG3162 COG3162, Predicted membrane protein Function unknown 156937952 Nonpathogen - hypothetical protein Igni_1164 1 None None None 156937635 Nonpathogen - hypothetical protein Igni_0842 1 None None None 156937333 Nonpathogen - shikimate kinase Igni_0540 29 COG1685 COG1685, Archaeal shikimate kinase Amino acid transport and metabolism / Coenzyme metabolism 156936922 Common - tRNA/rRNA methyltransferase (SpoU) Igni_0127 129 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 156937083 Common - Nucleotidyl transferase Igni_0289 230 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 156937650 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Igni_0857 185 COG0388 COG0388, Predicted amidohydrolase General function prediction only 156937313 Nonpathogen - hypothetical protein Igni_0520 1 None None None 156936885 Common - Uroporphyrinogen III synthase HEM4 Igni_0090 40 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 156937358 Nonpathogen - hypothetical protein Igni_0565 1 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 156936852 Common - L-2-aminoadipate N-acetyltransferase Igni_0057 92 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 156936968 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Igni_0173 11 COG1149 COG1149, MinD superfamily P-loop ATPase containing an inserted ferredoxin domain Energy production and conversion 156937051 Common - AMP-dependent synthetase and ligase Igni_0256 209 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 156937167 Common - translation factor SUA5 Igni_0373 228 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 156937607 Common - phosphoesterase, RecJ domain protein Igni_0814 30 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 156938052 Common - SAM-dependent methyltransferase Igni_1265 117 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 156937629 Nonpathogen - Translin Igni_0836 21 COG2178 COG2178, Predicted RNA-binding protein of the translin family Translation, ribosomal structure and biogenesis 156937315 Nonpathogen - hypothetical protein Igni_0522 1 None None None 156938182 Nonpathogen - hypothetical protein Igni_1395 6 COG2083 COG2083, Uncharacterized protein conserved in archaea Function unknown 156937564 Nonpathogen - hypothetical protein Igni_0771 2 None None None 156938102 Nonpathogen - hypothetical protein Igni_1315 1 None None None 156937266 Common - ABC-type tungstate transport system permease component-like protein Igni_0472 61 COG2998 TupB, ABC-type tungstate transport system, permease component Coenzyme metabolism 156937415 Common - UDP-glucose 6-dehydrogenase Igni_0622 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 156937404 Common - S-adenosylmethionine decarboxylase related Igni_0611 68 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 156937353 Common - thiazole biosynthesis enzyme Igni_0560 31 COG1635 THI4, Flavoprotein involved in thiazole biosynthesis Coenzyme metabolism 156936875 Common - Cupin 2, conserved barrel domain protein Igni_0080 42 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 156937582 Common - Radical SAM domain protein Igni_0789 108 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 156936986 Common - DEAD/DEAH box helicase domain protein Igni_0191 238 COG1201 Lhr, Lhr-like helicases General function prediction only 156937195 Common - CutA1 divalent ion tolerance protein Igni_0401 111 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 156937712 Common - camphor resistance protein CrcB Igni_0921 181 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 156936863 Nonpathogen - hypothetical protein Igni_0068 1 None None None 156937657 Common - HhH-GPD family protein Igni_0864 238 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 156937535 Nonpathogen - hypothetical protein Igni_0742 1 None None None 156937698 Nonpathogen - LSU ribosomal protein L15E Igni_0907 34 COG1632 RPL15A, Ribosomal protein L15E Translation, ribosomal structure and biogenesis 156938065 Nonpathogen - LSU ribosomal protein L19E Igni_1278 34 COG2147 RPL19A, Ribosomal protein L19E Translation, ribosomal structure and biogenesis 156937322 Common - sulfide reductase, subunit B Igni_0529 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 156937510 Common - phosphoadenosine phosphosulfate reductase Igni_0717 33 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 156937156 Common - prolyl-tRNA synthetase Igni_0362 242 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937785 Nonpathogen - hypothetical protein Igni_0995 1 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 156937942 Nonpathogen - hypothetical protein Igni_1154 3 None None None 156937103 Nonpathogen - DNA-binding protein containing a Zn-ribbon domain-like protein Igni_0309 24 COG1571 COG1571, Predicted DNA-binding protein containing a Zn-ribbon domain General function prediction only 156937265 Common - ABC-type tungstate transport system periplasmic component-like protein Igni_0471 97 COG4662 TupA, ABC-type tungstate transport system, periplasmic component Coenzyme metabolism 156937691 Common - Fmu (Sun) domain protein Igni_0900 192 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 156937164 Nonpathogen - hypothetical protein Igni_0370 1 None None None 156938199 Nonpathogen - SSU ribosomal protein S14P Igni_1412 17 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 156937903 Common - Methyltransferase type 11 Igni_1115 46 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 156937576 Nonpathogen - hypothetical protein Igni_0783 4 COG1665 COG1665, Uncharacterized protein conserved in archaea Function unknown 156937128 Common - Phosphoribosylaminoimidazole carboxylase Igni_0334 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 156937771 Common - Proteasome endopeptidase complex Igni_0980 48 COG0638 PRE1, 20S proteasome, alpha and beta subunits Posttranslational modification, protein turnover, chaperones 156937114 Nonpathogen - hypothetical protein Igni_0320 3 None None None 156937643 Common - 2'-5' RNA ligase Igni_0850 103 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 156937118 Common - porphobilinogen synthase Igni_0324 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 156937523 Common - inner-membrane translocator Igni_0730 132 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 156938041 Common - beta-lactamase domain protein Igni_1254 102 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 156936838 Common - aspartate carbamoyltransferase, regulatory subunit Igni_0043 65 COG1781 PyrI, Aspartate carbamoyltransferase, regulatory subunit Nucleotide transport and metabolism 156938039 Common - phosphoribosylformylglycinamidine synthase II Igni_1252 235 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 156937707 Common - aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit A Igni_0916 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 156938077 Nonpathogen - hypothetical protein Igni_1290 3 None None None 156938219 Nonpathogen - hypothetical protein Igni_1432 2 None None None 156937867 Common - deoxyribose-phosphate aldolase Igni_1079 127 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 156937096 Nonpathogen - major facilitator superfamily MFS_1 Igni_0302 1 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 156937684 Common - transketolase subunit B Igni_0891 228 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 156937690 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Igni_0899 144 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 156936841 Nonpathogen - hypothetical protein Igni_0046 7 COG1412 COG1412, Uncharacterized proteins of PilT N-term./Vapc superfamily General function prediction only 156937246 Nonpathogen - Protein of unknown function DUF137 Igni_0452 30 COG1701 COG1701, Uncharacterized protein conserved in archaea Function unknown 156937551 Common - mevalonate kinase Igni_0758 61 COG1577 ERG12, Mevalonate kinase Lipid metabolism 156936942 Common - daunorubicin resistance ABC transporter, inner membrane subunit B Igni_0147 198 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 156937764 Nonpathogen - hypothetical protein Igni_0973 1 None None None 156937500 Common - PP-loop domain protein Igni_0707 72 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 156938117 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Igni_1330 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 156937362 Nonpathogen - hypothetical protein Igni_0569 1 None None None 156936931 Nonpathogen - hypothetical protein Igni_0136 1 None None None 156937212 Common - Reverse gyrase Igni_0418 235 COG1110 COG1110, Reverse gyrase DNA replication, recombination, and repair 156936856 Nonpathogen - TOPRIM domain protein Igni_0061 34 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 156938181 Nonpathogen - helix-turn-helix domain protein Igni_1394 33 COG1395 COG1395, Predicted transcriptional regulator Transcription 156937778 Nonpathogen - hypothetical protein Igni_0988 1 None None None 156937673 Common - Inorganic diphosphatase Igni_0880 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 156937391 Common - putative signal transduction protein with CBS domains Igni_0598 213 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 156938059 Nonpathogen - Uncharacterized protein-like protein Igni_1272 1 COG1860 COG1860, Uncharacterized protein conserved in archaea Function unknown 156937058 Nonpathogen - hypothetical protein Igni_0263 5 None None None 156936895 Common - peptidase M24 Igni_0100 244 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 156938122 Common - THUMP domain protein Igni_1335 25 COG1818 COG1818, Predicted RNA-binding protein, contains THUMP domain General function prediction only 156937482 Common - Creatininase Igni_0689 80 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 156938009 Common - CBS domain containing protein Igni_1222 115 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 156937423 Common - Radical SAM domain protein Igni_0630 206 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 156937953 Nonpathogen - hypothetical protein Igni_1165 2 None None None 156937958 Common - protein of unknown function DUF87 Igni_1170 98 COG0433 COG0433, Predicted ATPase General function prediction only 156936903 Common - phosphate ABC transporter, inner membrane subunit PstC Igni_0108 222 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 156936884 Common - uroporphyrin-III C-methyltransferase Igni_0089 199 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 156936943 Nonpathogen - hypothetical protein Igni_0148 6 None None None 156937092 Nonpathogen - hypothetical protein Igni_0298 1 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 156937399 Common - AMMECR1 domain protein Igni_0606 76 COG2078 AMMECR1, Uncharacterized conserved protein Function unknown 156938083 Nonpathogen - putative transcriptional regulator Igni_1296 1 COG2345 COG2345, Predicted transcriptional regulator Transcription 156937206 Nonpathogen - thiamine biosynthesis protein Igni_0412 12 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 156937190 Nonpathogen - Ser-tRNA(Thr) hydrolase Igni_0396 28 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937646 Common - Ser-tRNA(Thr) hydrolase Igni_0853 243 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937974 Common - beta-lactamase domain protein Igni_1186 91 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 156937877 Nonpathogen - hypothetical protein Igni_1089 1 None None None 156938222 Common - aspartyl-tRNA synthetase Igni_1435 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 156936954 Nonpathogen - hypothetical protein Igni_0159 1 None None None 156937430 Common - GMP synthase (glutamine-hydrolyzing) Igni_0637 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 156937599 Nonpathogen - hypothetical protein Igni_0806 5 None None None 156937199 Nonpathogen - hypothetical protein Igni_0405 1 None None None 156936810 Nonpathogen - hypothetical protein Igni_0015 1 None None None 156938140 Nonpathogen - Radical SAM domain protein Igni_1353 22 COG1549 COG1549, Queuine tRNA-ribosyltransferases, contain PUA domain Translation, ribosomal structure and biogenesis 156937992 Nonpathogen - hypothetical protein Igni_1205 1 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 156937378 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Igni_0585 124 COG0756 Dut, dUTPase Nucleotide transport and metabolism 156937323 Nonpathogen - hypothetical cytochrome Igni_0530 3 None None None 156937108 Common - cytochrome c assembly protein Igni_0314 144 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 156938169 Common - lysine 2,3-aminomutase YodO family protein Igni_1382 128 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 156938159 Nonpathogen - Transcription initiation factor IIB (TFIIB) Igni_1372 34 COG1405 SUA7, Transcription initiation factor TFIIIB, Brf1 subunit/Transcription initiation factor TFIIB Transcription 156937667 Common - dihydropteroate synthase-related protein Igni_0874 31 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 156937772 Common - hypothetical protein Igni_0981 39 None None None 156938011 Nonpathogen - hypothetical protein Igni_1224 1 None None None 156937881 Nonpathogen - LSU ribosomal protein L35AE Igni_1093 9 COG2451 COG2451, Ribosomal protein L35AE/L33A Translation, ribosomal structure and biogenesis 156937888 Common - tryptophan synthase, beta chain Igni_1100 224 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 156937809 Nonpathogen - binding-protein-dependent transport systems inner membrane component Igni_1019 1 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 156938078 Nonpathogen - hypothetical protein Igni_1291 1 None None None 156937967 Nonpathogen - NGN domain protein Igni_1179 34 COG0250 NusG, Transcription antiterminator Transcription 156937660 Common - exsB protein Igni_0867 178 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 156937932 Common - NADH dehydrogenase (quinone) Igni_1144 181 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 156938002 Nonpathogen - hypothetical protein Igni_1215 1 None None None 156937374 Nonpathogen - 4-vinyl reductase, 4VR Igni_0581 1 COG1719 COG1719, Predicted hydrocarbon binding protein (contains V4R domain) General function prediction only 156937138 Common - phosphoenolpyruvate synthase Igni_0344 41 COG3382 COG3382, Uncharacterized conserved protein Function unknown 156937445 Nonpathogen - DNA-directed RNA polymerase, subunit H Igni_0652 29 COG2012 RPB5, DNA-directed RNA polymerase, subunit H, RpoH/RPB5 Transcription 156937245 Nonpathogen - LSU ribosomal protein L12AE Igni_0451 33 COG2058 RPP1A, Ribosomal protein L12E/L44/L45/RPP1/RPP2 Translation, ribosomal structure and biogenesis 156938229 Common - anthranilate phosphoribosyltransferase Igni_1442 221 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 156937811 Common - extracellular solute-binding protein, family 5 Igni_1021 189 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 156937345 Nonpathogen - hypothetical protein Igni_0552 2 None None None 156937758 Nonpathogen - hypothetical protein Igni_0967 1 None None None 156937748 Nonpathogen - hypothetical protein Igni_0957 1 None None None 156936800 Common - Radical SAM domain protein Igni_0005 42 COG5014 COG5014, Predicted Fe-S oxidoreductase General function prediction only 156937474 Nonpathogen - hypothetical protein Igni_0681 1 None None None 156937541 Common - Cobalamin-independent synthase MetE, N-terminal domain protein Igni_0748 49 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 156937575 Nonpathogen - KH, type 1, domain protein Igni_0782 34 COG1094 COG1094, Predicted RNA-binding protein (contains KH domains) General function prediction only 156937795 Common - peptidase S8 and S53, subtilisin, kexin, sedolisin Igni_1005 20 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 156937015 Common - valyl-tRNA synthetase Igni_0220 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937558 Common - translation initiation factor 2 subunit alpha (aeIF-2a) Igni_0765 40 COG1093 SUI2, Translation initiation factor 2, alpha subunit (eIF-2alpha) Translation, ribosomal structure and biogenesis 156938046 Common - pyruvate ferredoxin oxidoreductase, beta subunit Igni_1259 113 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 156937569 Nonpathogen - hypothetical protein Igni_0776 1 None None None 156937592 Common - peptidase M48, Ste24p Igni_0799 184 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 156937010 Common - shikimate dehydrogenase Igni_0215 224 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 156937822 Common - Aldehyde ferredoxin oxidoreductase Igni_1032 57 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 156937585 Nonpathogen - hypothetical protein Igni_0792 1 None None None 156938023 Common - class II aldolase/adducin family protein Igni_1236 112 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 156937280 Nonpathogen - transcriptional regulator, XRE family Igni_0486 16 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 156937800 Nonpathogen - hypothetical protein Igni_1010 17 COG1955 FlaJ, Archaeal flagella assembly protein J Cell motility and secretion / Intracellular trafficking and secretion 156937458 Nonpathogen - putative CRISPR-associated protein, APE2256 family Igni_0665 10 COG4006 COG4006, Uncharacterized protein conserved in archaea Function unknown 156937275 Nonpathogen - endonuclease (RecB family)-like protein Igni_0481 8 COG4998 COG4998, Predicted endonuclease (RecB family) DNA replication, recombination, and repair 156938139 Nonpathogen - GTP cyclohydrolase Iia Igni_1352 6 COG2429 COG2429, Uncharacterized conserved protein Function unknown 156937296 Nonpathogen - hypothetical protein Igni_0502 1 None None None 156937856 Common - protein of unknown function DUF433 Igni_1068 30 COG2442 COG2442, Uncharacterized conserved protein Function unknown 156937893 Nonpathogen - ZPR1-related zinc finger protein Igni_1105 29 COG1779 COG1779, C4-type Zn-finger protein General function prediction only 156936866 Nonpathogen - hypothetical protein Igni_0071 1 None None None 156936829 Nonpathogen - hypothetical protein Igni_0034 4 COG0714 COG0714, MoxR-like ATPases General function prediction only 156937732 Nonpathogen - methyltransferase Igni_0941 35 COG2520 COG2520, Predicted methyltransferase General function prediction only 156938099 Nonpathogen - hypothetical protein Igni_1312 1 None None None 156937455 Nonpathogen - hypothetical protein Igni_0662 1 None None None 156937987 Common - histone deacetylase superfamily Igni_1200 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 156938105 Nonpathogen - hypothetical protein Igni_1318 1 None None None 156937488 Common - aconitase subunit 1 Igni_0695 39 COG1679 COG1679, Uncharacterized conserved protein Function unknown 156937218 Common - AIR synthase related protein domain protein Igni_0424 21 COG1973 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 156938206 Common - RNA modification enzyme, MiaB family Igni_1419 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 156937222 Common - ribose 5-phosphate isomerase Igni_0428 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 156937229 Nonpathogen - hypothetical protein Igni_0435 1 None None None 156937838 Nonpathogen - hypothetical protein Igni_1049 1 None None None 156937146 Nonpathogen - hypothetical protein Igni_0352 7 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 156936825 Common - imidazole glycerol phosphate synthase subunit hisH Igni_0030 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 156937210 Nonpathogen - (S)-2,3-Di-O-geranylgeranyl glyceryl phosphate synthase Igni_0416 42 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 156936868 Nonpathogen - hypothetical protein Igni_0073 1 None None None 156937864 Common - 2-oxoglutarate ferredoxin oxidoreductase, gamma subunit Igni_1076 83 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 156936925 Common - TatD-related deoxyribonuclease Igni_0130 196 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 156938021 Nonpathogen - hypothetical protein Igni_1234 1 None None None 156936861 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Igni_0066 181 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 156937651 Common - transcriptional regulator, PadR family Igni_0858 31 COG1695 COG1695, Predicted transcriptional regulators Transcription 156937517 Nonpathogen - LSU ribosomal protein L24E Igni_0724 32 COG2075 RPL24A, Ribosomal protein L24E Translation, ribosomal structure and biogenesis 156938115 Common - putative RNA methylase Igni_1328 42 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 156937745 Nonpathogen - hypothetical protein Igni_0954 1 COG4742 COG4742, Predicted transcriptional regulator Transcription 156938210 Nonpathogen - hypothetical protein Igni_1423 6 None None None 156936823 Nonpathogen - hypothetical protein Igni_0028 2 None None None 156938153 Common - Nickel-dependent hydrogenase small subunit, N-terminal domain protein Igni_1366 77 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 156937159 Nonpathogen - hypothetical protein Igni_0365 1 None None None 156937693 Common - amidophosphoribosyltransferase Igni_0902 231 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 156937306 Common - glutamyl-tRNA reductase Igni_0512 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 156937940 Nonpathogen - Protein of unknown function DUF516 Igni_1152 28 COG1650 COG1650, Uncharacterized protein conserved in archaea Function unknown 156937211 Nonpathogen - Alba, DNA/RNA-binding protein Igni_0417 17 COG1581 Ssh10b, Archaeal DNA-binding protein Transcription 156937830 Nonpathogen - transcriptional regulator, AbrB family Igni_1041 4 COG2002 AbrB, Regulators of stationary/sporulation gene expression Transcription 156937783 Common - NAD-dependent epimerase/dehydratase Igni_0993 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 156937343 Common - ABC transporter related Igni_0550 248 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 156937922 Nonpathogen - CRISPR-associated protein Cas2 Igni_1134 6 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 156937331 Nonpathogen - Uncharacterized protein-like protein Igni_0538 20 COG2090 COG2090, Uncharacterized protein conserved in archaea Function unknown 156937435 Nonpathogen - hypothetical protein Igni_0642 2 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 156937017 Nonpathogen - nucleotide kinase-like protein Igni_0222 28 COG1936 COG1936, Predicted nucleotide kinase (related to CMP and AMP kinases) Nucleotide transport and metabolism 156936985 Nonpathogen - hypothetical protein Igni_0190 6 None None None 156938133 Common - LSU ribosomal protein L2P Igni_1346 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 156938218 Common - AAA family ATPase, CDC48 subfamily Igni_1431 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 156937085 Nonpathogen - protein of unknown function DUF358 Igni_0291 21 COG1901 COG1901, Uncharacterized conserved protein Function unknown 156937891 Common - methylthioadenosine phosphorylase Igni_1103 160 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 156936936 Nonpathogen - hypothetical protein Igni_0141 1 None None None 156938184 Nonpathogen - hypothetical protein Igni_1397 8 None None None 156937609 Nonpathogen - hypothetical protein Igni_0816 1 None None None 156937000 Common - ATPase associated with various cellular activities, AAA_3 Igni_0205 179 COG0714 COG0714, MoxR-like ATPases General function prediction only 156937898 Common - glutamyl-tRNA synthetase Igni_1110 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 156937234 Common - glycosyl transferase, family 2 Igni_0440 212 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 156937047 Common - ribose-phosphate pyrophosphokinase Igni_0252 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 156936837 Common - oxidoreductase FAD/NAD(P)-binding domain protein Igni_0042 88 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 156936858 Nonpathogen - hypothetical protein Igni_0063 1 None None None 156937035 Nonpathogen - Protein of unknown function DUF54 Igni_0240 21 COG1325 COG1325, Predicted exosome subunit Translation, ribosomal structure and biogenesis 156937007 Nonpathogen - hypothetical protein Igni_0212 3 COG1571 COG1571, Predicted DNA-binding protein containing a Zn-ribbon domain General function prediction only 156937689 Nonpathogen - hypothetical protein Igni_0898 1 None None None 156937905 Common - protein of unknown function DUF699, ATPase putative Igni_1117 46 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 156936843 Nonpathogen - hypothetical protein Igni_0048 1 None None None 156937258 Nonpathogen - hypothetical protein Igni_0464 1 None None None 156937068 Common - amidohydrolase Igni_0273 36 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 156937140 Common - Adenylosuccinate synthetase Igni_0346 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 156937341 Common - phage integrase family protein Igni_0548 224 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 156937841 Nonpathogen - hypothetical protein Igni_1052 2 None None None 156937682 Nonpathogen - peptidase S16, lon domain protein Igni_0889 11 COG1750 COG1750, Archaeal serine proteases General function prediction only 156936958 Common - ABC transporter related Igni_0163 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 156937562 Nonpathogen - hypothetical protein Igni_0769 1 None None None 156937497 Common - phosphoribosyltransferase Igni_0704 96 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 156937162 Common - Radical SAM domain protein Igni_0368 224 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 156937028 Common - phosphoribosyltransferase Igni_0233 96 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 156936999 Nonpathogen - hypothetical protein Igni_0204 1 None None None 156937174 Nonpathogen - hypothetical protein Igni_0380 1 None None None 156937546 Nonpathogen - hypothetical protein Igni_0753 5 None None None 156937556 Nonpathogen - protein of unknown function DUF46 Igni_0763 36 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 156936805 Nonpathogen - hypothetical protein Igni_0010 1 None None None 156937080 Nonpathogen - LSU ribosomal protein L39E Igni_0286 5 COG2167 RPL39, Ribosomal protein L39E Translation, ribosomal structure and biogenesis 156937578 Nonpathogen - hypothetical protein Igni_0785 1 None None None 156936973 Nonpathogen - Mn2+-dependent serine/threonine protein kinase Igni_0178 35 COG3642 COG3642, Mn2+-dependent serine/threonine protein kinase Signal transduction mechanisms 156937848 Common - dimethyladenosine transferase Igni_1059 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 156937325 Common - RNA-3'-phosphate cyclase Igni_0532 47 COG0430 RCL1, RNA 3'-terminal phosphate cyclase RNA processing and modification 156936819 Nonpathogen - hypothetical protein Igni_0024 1 None None None 156938058 Nonpathogen - hypothetical protein Igni_1271 6 None None None 156937119 Common - protein of unknown function DUF124 Igni_0325 73 COG2013 COG2013, Uncharacterized conserved protein Function unknown 156937614 Nonpathogen - hypothetical protein Igni_0821 1 None None None 156937755 Common - LSU ribosomal protein L3P Igni_0964 85 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 156938107 Nonpathogen - hypothetical protein Igni_1320 1 None None None 156937467 Common - (NiFe) hydrogenase maturation protein HypF Igni_0674 126 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 156937710 Nonpathogen - Suppressor Mra1 Igni_0919 18 COG1756 Mra1, Uncharacterized conserved protein Function unknown 156938150 Nonpathogen - heat shock protein Hsp20 Igni_1363 28 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 156937165 Nonpathogen - hypothetical protein Igni_0371 1 None None None 156937521 Common - N2-acetyl-L-aminoadipate semialdehyde dehydrogenase Igni_0728 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 156937192 Common - amidohydrolase Igni_0398 38 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 156937311 Nonpathogen - hypothetical protein Igni_0518 1 None None None 156936965 Nonpathogen - hypothetical protein Igni_0170 4 None None None 156936854 Nonpathogen - putative transcription elongation factor Igni_0059 12 COG0195 NusA, Transcription elongation factor Transcription 156937094 Nonpathogen - Radical SAM domain protein Igni_0300 7 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 156937052 Common - Acyl-coenzyme A synthetase/AMP-(fatty) acid ligase-like protein Igni_0257 213 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 156938157 Nonpathogen - peptidase, zinc-dependent Igni_1370 19 COG1913 COG1913, Predicted Zn-dependent proteases General function prediction only 156937705 Common - ABC-type metal ion transport system periplasmic component/surface adhesin-like protein Igni_0914 8 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 156937699 Nonpathogen - hypothetical protein Igni_0908 1 COG1779 COG1779, C4-type Zn-finger protein General function prediction only 156937318 Common - metallophosphoesterase Igni_0525 40 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 156937918 Common - hypothetical protein Igni_1130 20 None None None 156937669 Nonpathogen - von Willebrand factor, type A Igni_0876 15 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 156937719 Common - arginyl-tRNA synthetase Igni_0928 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937723 Common - flavoprotein Igni_0932 25 COG1036 COG1036, Archaeal flavoproteins Energy production and conversion 156937766 Common - phosphate ABC transporter, periplasmic phosphate-binding protein Igni_0975 108 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 156937180 Common - CoA-binding domain protein Igni_0386 151 COG1042 COG1042, Acyl-CoA synthetase (NDP forming) Energy production and conversion 156937493 Nonpathogen - hypothetical protein Igni_0700 1 None None None 156937178 Common - histidinol dehydrogenase Igni_0384 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 156937026 Common - protein of unknown function DUF711 Igni_0231 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 156937355 Common - phosphoribosyl-AMP cyclohydrolase Igni_0562 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 156937413 Common - NADPH-dependent FMN reductase Igni_0620 78 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 156937270 Common - 3-hydroxy-3-methylglutaryl-coenzyme A reductase Igni_0476 49 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 156938174 Common - ornithine carbamoyltransferase Igni_1387 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 156937728 Common - O-methyltransferase, family 3 Igni_0937 7 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 156936911 Nonpathogen - hypothetical protein Igni_0116 5 None None None 156937633 Nonpathogen - hypothetical protein Igni_0840 5 COG1318 COG1318, Predicted transcriptional regulators Transcription 156937257 Nonpathogen - hypothetical protein Igni_0463 12 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 156937282 Common - Radical SAM domain protein Igni_0488 38 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 156937066 Nonpathogen - SSU ribosomal protein S24E Igni_0271 16 COG2004 RPS24A, Ribosomal protein S24E Translation, ribosomal structure and biogenesis 156937143 Common - phosphoribosyltransferase Igni_0349 71 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 156937099 Nonpathogen - hypothetical protein Igni_0305 7 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 156937781 Common - cysteinyl-tRNA synthetase Igni_0991 244 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937476 Common - glutamate-1-semialdehyde 2,1-aminomutase Igni_0683 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 156937883 Nonpathogen - Auxin Efflux Carrier Igni_1095 1 COG0679 COG0679, Predicted permeases General function prediction only 156937965 Common - signal recognition particle-docking protein FtsY Igni_1177 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 156938016 Nonpathogen - FeoA family protein Igni_1229 21 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 156937243 Nonpathogen - hypothetical protein Igni_0449 9 COG1818 COG1818, Predicted RNA-binding protein, contains THUMP domain General function prediction only 156938163 Common - protein of unknown function DUF82 Igni_1376 33 COG1656 COG1656, Uncharacterized conserved protein Function unknown 156937934 Nonpathogen - NADH-ubiquinone/plastoquinone oxidoreductase, chain 6 Igni_1146 1 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 156937090 Common - glyceraldehyde-3-phosphate ferredoxin oxidoreductase Igni_0296 26 COG2414 COG2414, Aldehyde:ferredoxin oxidoreductase Energy production and conversion 156937503 Nonpathogen - transcriptional regulator, TrmB Igni_0710 4 COG1497 COG1497, Predicted transcriptional regulator Transcription 156937183 Nonpathogen - hypothetical protein Igni_0389 1 None None None 156937188 Nonpathogen - sodium/hydrogen exchanger Igni_0394 7 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 156937662 Common - HD superfamily phosphohydrolase-like protein Igni_0869 87 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 156937647 Nonpathogen - proliferating cell nuclear antigen PcnA Igni_0854 34 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 156937956 Common - Polyprenyl synthetase Igni_1168 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 156936893 Common - hypothetical protein Igni_0098 21 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 156936905 Common - t-RNA-binding domain protein Igni_0110 186 COG0073 ARC1, EMAP domain General function prediction only 156936827 Nonpathogen - hypothetical protein Igni_0032 1 None None None 156937951 Nonpathogen - protein of unknown function DUF75 Igni_1163 31 COG1938 COG1938, Archaeal enzymes of ATP-grasp superfamily General function prediction only 156936978 Nonpathogen - DNA-directed RNA polymerase, subunit D Igni_0183 34 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 156936878 Nonpathogen - DNA-directed RNA polymerase, subunit E'' Igni_0083 17 COG2093 COG2093, DNA-directed RNA polymerase, subunit E'' Transcription 156937223 Nonpathogen - hypothetical protein Igni_0429 1 None None None 156937486 Common - AAA family ATPase, CDC48 subfamily Igni_0693 249 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 156937087 Common - putative circadian clock protein, KaiC Igni_0293 90 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 156938170 Common - translation elongation factor 2 (EF-2/EF-G) Igni_1383 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 156937597 Common - isopentenyl-diphosphate delta-isomerase, type 2 Igni_0804 80 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 156937538 Nonpathogen - hypothetical protein Igni_0745 1 None None None 156937603 Nonpathogen - hypothetical protein Igni_0810 1 None None None 156937875 Common - 3-isopropylmalate dehydratase Igni_1087 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 156937421 Common - Alcohol dehydrogenase, zinc-binding domain protein Igni_0628 175 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 156938201 Common - CBS domain containing protein Igni_1414 201 COG0517 COG0517, FOG: CBS domain General function prediction only 156937039 Common - DNA-directed RNA polymerase, subunit A Igni_0244 247 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 156937134 Common - Radical SAM domain protein Igni_0340 159 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 156938090 Nonpathogen - hypothetical protein Igni_1303 1 None None None 156938137 Common - nicotinate-nucleotide pyrophosphorylase (carboxylating) Igni_1350 202 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 156937457 Common - N2-acetyl-L-lysine deacetylase Igni_0664 157 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 156937004 Common - ribosomal RNA-processing protein RRP42 Igni_0209 52 COG2123 COG2123, RNase PH-related exoribonuclease Translation, ribosomal structure and biogenesis 156937854 Nonpathogen - hypothetical protein Igni_1065 1 None None None 156937277 Common - siroheme synthase Igni_0483 34 COG1648 CysG, Siroheme synthase (precorrin-2 oxidase/ferrochelatase domain) Coenzyme metabolism 156938112 Nonpathogen - hypothetical protein Igni_1325 1 None None None 156936945 Common - leucyl-tRNA synthetase Igni_0150 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156937829 Common - cytidyltransferase-related domain protein Igni_1040 153 COG0615 TagD, Cytidylyltransferase Cell envelope biogenesis, outer membrane / Lipid metabolism 156938177 Common - molybdenum cofactor synthesis domain Igni_1390 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 156937807 Common - Isoleucyl-tRNA synthetase Igni_1017 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 156938037 Nonpathogen - hypothetical protein Igni_1250 1 None None None 156937560 Nonpathogen - SSU ribosomal protein S8E Igni_0767 34 COG2007 RPS8A, Ribosomal protein S8E Translation, ribosomal structure and biogenesis 156937985 Nonpathogen - adenylate kinase-like protein Igni_1198 22 COG2019 AdkA, Archaeal adenylate kinase Nucleotide transport and metabolism 156937639 Nonpathogen - transcriptional regulators-like protein Igni_0846 13 COG1318 COG1318, Predicted transcriptional regulators Transcription 156937756 Nonpathogen - LSU ribosomal protein L4P Igni_0965 34 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 156937663 Nonpathogen - glycosidase, PH1107-related Igni_0870 11 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 156936797 Common - FAD linked oxidase domain protein Igni_0002 195 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 156938076 Nonpathogen - hypothetical protein Igni_1289 1 None None None 156936871 Nonpathogen - hypothetical protein Igni_0076 1 None None None 156937734 Nonpathogen - IMP biosynthesis enzyme PurP-like protein Igni_0943 20 COG1759 COG1759, ATP-utilizing enzymes of ATP-grasp superfamily (probably carboligases) General function prediction only 156937216 Nonpathogen - hypothetical protein Igni_0422 5 None None None 156937363 Common - asparagine synthase (glutamine-hydrolyzing) Igni_0570 185 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 156938044 Common - pyruvate ferredoxin oxidoreductase, delta subunit Igni_1257 112 COG1144 COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit Energy production and conversion 156938121 Nonpathogen - riboflavin synthase alpha chain Igni_1334 22 COG1731 COG1731, Archaeal riboflavin synthase Coenzyme metabolism 156938190 Common - lysine biosynthesis enzyme LysX Igni_1403 111 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 156937910 Nonpathogen - hypothetical protein Igni_1122 2 None None None 156938064 Nonpathogen - LSU ribosomal protein L18P Igni_1277 34 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 156936956 Common - ABC transporter related Igni_0161 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 156937770 Nonpathogen - LSU ribosomal protein L37E Igni_0979 29 COG2126 RPL37A, Ribosomal protein L37E Translation, ribosomal structure and biogenesis 156937347 Common - Phosphopantothenoylcysteine decarboxylase Igni_0554 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 156937372 Nonpathogen - hypothetical protein Igni_0579 1 None None None 156937447 Nonpathogen - hypothetical protein Igni_0654 1 None None None 156937148 Common - sugar fermentation stimulation protein Igni_0354 50 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 156937207 Common - hydrogenase formation HypD protein Igni_0413 109 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 156937439 Common - hypothetical protein Igni_0646 3 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 156937012 Nonpathogen - hypothetical protein Igni_0217 1 None None None 156937308 Nonpathogen - hypothetical protein Igni_0515 2 None None None 156936981 Common - SSU ribosomal protein S9P Igni_0186 97 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 156937972 Nonpathogen - tRNA (guanine-N(2)-)-methyltransferase Igni_1184 38 COG1867 TRM1, N2,N2-dimethylguanosine tRNA methyltransferase Translation, ribosomal structure and biogenesis 156938220 Common - Wyosine base formation Igni_1433 36 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 156937793 Nonpathogen - hypothetical protein Igni_1003 1 None None None 156937110 Common - Thioredoxin domain Igni_0316 7 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 156937124 Nonpathogen - hypothetical protein Igni_0330 1 None None None 156937970 Nonpathogen - LSU ribosomal protein L10P Igni_1182 34 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 156937073 Common - metallophosphoesterase Igni_0278 123 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 156937590 Nonpathogen - hypothetical protein Igni_0797 5 None None None 156937847 Common - 3-hydroxyacyl-CoA dehydrogenase, NAD-binding Igni_1058 191 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 156937832 Common - PHP C-terminal domain protein Igni_1043 74 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 156937200 Common - aminotransferase, class I and II Igni_0406 238 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 156937548 Nonpathogen - hypothetical protein Igni_0755 1 None None None 156938160 Nonpathogen - DNA-(apurinic or apyrimidinic site) lyase Igni_1373 12 COG4047 COG4047, Uncharacterized protein conserved in archaea Function unknown 156937813 Nonpathogen - VanZ family protein Igni_1023 1 COG5652 COG5652, Predicted integral membrane protein Function unknown 156936997 Nonpathogen - hypothetical protein Igni_0202 1 None None None 156937157 Common - protein of unknown function DUF100 Igni_0363 37 COG1980 COG1980, Archaeal fructose 1,6-bisphosphatase Carbohydrate transport and metabolism 156938043 Common - pyruvate/ketoisovalerate oxidoreductase, gamma subunit Igni_1256 95 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 156937600 Nonpathogen - hypothetical protein Igni_0807 1 None None None 156938186 Common - carbamoyl-phosphate synthase large subunit Igni_1399 238 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 156936934 Common - Extracellular ligand-binding receptor Igni_0139 119 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 156937242 Common - aldo/keto reductase Igni_0448 176 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 156937232 Common - Appr-1-p processing domain protein Igni_0438 117 COG2110 COG2110, Predicted phosphatase homologous to the C-terminal domain of histone macroH2A1 General function prediction only 156937680 Nonpathogen - hypothetical protein Igni_0887 1 None None None 156937863 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Igni_1075 39 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 156937925 Common - CRISPR-associated helicase Cas3 Igni_1137 89 COG1203 COG1203, Predicted helicases General function prediction only 156936845 Nonpathogen - hypothetical protein Igni_0050 9 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 156937301 Nonpathogen - adenylate cyclase Igni_0507 29 COG1437 CyaB, Adenylate cyclase, class 2 (thermophilic) Nucleotide transport and metabolism 156937528 Common - protein of unknown function DUF87 Igni_0735 82 COG0433 COG0433, Predicted ATPase General function prediction only 156937907 Nonpathogen - hypothetical protein Igni_1119 1 None None None 156937379 Common - Undecaprenyl pyrophosphate synthetase Igni_0586 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 156937049 Nonpathogen - hypothetical protein Igni_0254 1 None None None 156937019 Common - dCTP deaminase Igni_0224 152 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 156937742 Nonpathogen - hypothetical protein Igni_0951 1 None None None 156937172 Nonpathogen - protein of unknown function DUF35 Igni_0378 33 COG1545 COG1545, Predicted nucleic-acid-binding protein containing a Zn-ribbon General function prediction only 156938143 Common - peptidase U62, modulator of DNA gyrase Igni_1356 123 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 156938126 Common - ABC transporter related Igni_1339 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 156936918 Nonpathogen - glutamine amidotransferase-like protein Igni_0123 4 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 156937042 Common - SSU ribosomal protein S12P Igni_0247 235 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 156937009 Nonpathogen - hypothetical protein Igni_0214 1 None None None 156937037 Common - HAD-superfamily hydrolase, subfamily IB (PSPase-like) Igni_0242 144 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 156937298 Nonpathogen - hydrogenase maturation protease Igni_0504 1 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 156938028 Nonpathogen - hypothetical protein Igni_1241 1 None None None 156937261 Nonpathogen - CRISPR-associated protein Cas4 Igni_0467 2 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 156938113 Common - Arsenite-transporting ATPase Igni_1326 93 COG0003 ArsA, Predicted ATPase involved in chromosome partitioning Cell division and chromosome partitioning 156937911 Nonpathogen - protein of unknown function DUF127 Igni_1123 31 COG1303 COG1303, Uncharacterized protein conserved in archaea Function unknown 156937948 Nonpathogen - hypothetical protein Igni_1160 1 None None None 156937625 Nonpathogen - Uncharacterized protein putative amidase-like protein Igni_0832 1 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 156936834 Nonpathogen - hypothetical protein Igni_0039 6 None None None 156938203 Common - phosphoribosylglycinamide formyltransferase 2 Igni_1416 205 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 156937515 Common - ATPase involved in chromosome partitioning-like protein Igni_0722 22 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 156937338 Common - proton-translocating NADH-quinone oxidoreductase, chain M Igni_0545 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 156937132 Common - Polyprenyl synthetase Igni_0338 97 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 156938034 Nonpathogen - Alcohol dehydrogenase GroES domain protein Igni_1247 3 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 156937366 Common - amino acid permease-associated region Igni_0573 151 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 156938155 Nonpathogen - hypothetical protein Igni_1368 7 None None None 156937403 Nonpathogen - DNA polymerase sliding clamp subunit A Igni_0610 34 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 156936817 Nonpathogen - RNA-binding protein, containing PUA domain Igni_0022 34 COG2016 COG2016, Predicted RNA-binding protein (contains PUA domain) Translation, ribosomal structure and biogenesis 156936906 Common - histone deacetylase superfamily Igni_0111 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 156938216 Nonpathogen - hypothetical protein Igni_1429 1 None None None 156937567 Nonpathogen - hypothetical protein Igni_0774 1 None None None 156937385 Nonpathogen - Ribonuclease P subunit Igni_0592 13 COG1588 POP4, RNase P/RNase MRP subunit p29 Translation, ribosomal structure and biogenesis 156938084 Nonpathogen - replicative DNA helicase Mcm Igni_1297 34 COG1241 MCM2, Predicted ATPase involved in replication control, Cdc46/Mcm family DNA replication, recombination, and repair 156937753 Common - MMPL domain protein Igni_0962 42 COG2409 COG2409, Predicted drug exporters of the RND superfamily General function prediction only 156937150 Nonpathogen - hypothetical protein Igni_0356 7 None None None 156936891 Common - thermosome Igni_0096 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 156937262 Common - beta-lactamase domain protein Igni_0468 27 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 156937894 Nonpathogen - LSU ribosomal protein L44E Igni_1106 25 COG1631 RPL42A, Ribosomal protein L44E Translation, ribosomal structure and biogenesis 156936983 Common - SSU ribosomal protein S2P Igni_0188 194 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 156938093 Nonpathogen - phosphohydrolase (DHH superfamily)-like protein Igni_1306 10 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 156936882 Nonpathogen - prefoldin, alpha subunit Igni_0087 22 COG1730 GIM5, Predicted prefoldin, molecular chaperone implicated in de novo protein folding Posttranslational modification, protein turnover, chaperones 156936898 Nonpathogen - SSU ribosomal protein S27E Igni_0103 34 COG2051 RPS27A, Ribosomal protein S27E Translation, ribosomal structure and biogenesis 156936889 Nonpathogen - hypothetical protein Igni_0094 3 None None None 156938018 Nonpathogen - putative phosphohistidine phosphatase, SixA Igni_1231 12 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 156937054 Common - phosphoesterase, putative Igni_0259 39 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 156936917 Common - transcriptional regulator, AsnC family Igni_0122 98 COG1522 Lrp, Transcriptional regulators Transcription 156938146 Common - hypothetical multiheme cytochrome Igni_1359 17 None None None 156938061 Nonpathogen - LSU ribosomal protein L15P Igni_1274 22 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 156937717 Common - phosphoribosylanthranilate isomerase Igni_0926 179 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 156936880 Common - succinyl-CoA synthetase (ADP-forming) alpha subunit Igni_0085 215 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 156937316 Nonpathogen - Protein of unknown function DUF429 Igni_0523 11 COG2410 COG2410, Uncharacterized conserved protein Function unknown 156937237 Common - membrane protein-like protein Igni_0443 19 COG2426 COG2426, Predicted membrane protein Function unknown 156937775 Nonpathogen - hypothetical protein Igni_0984 6 None None None 156937255 Nonpathogen - CRISPR-associated protein, Cmr5 family Igni_0461 2 None None None 156937287 Nonpathogen - hypothetical protein Igni_0493 5 None None None 156937411 Nonpathogen - hypothetical protein Igni_0618 1 None None None 156937272 Common - tRNA-guanine transglycosylase, various specificities Igni_0478 227 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 156937631 Nonpathogen - LSU ribosomal protein L40E Igni_0838 14 COG1552 RPL40A, Ribosomal protein L40E Translation, ribosomal structure and biogenesis 156937176 Nonpathogen - Protein of unknown function DUF424 Igni_0382 20 COG2412 COG2412, Uncharacterized conserved protein Function unknown 156937383 Common - SSU ribosomal protein S3P Igni_0590 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 156937616 Nonpathogen - hypothetical protein Igni_0823 1 None None None 156937676 Nonpathogen - SpoVT/AbrB domain protein Igni_0883 25 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 156937626 Nonpathogen - hypothetical protein Igni_0833 1 None None None 156936848 Common - DEAD_2 domain protein Igni_0053 44 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 156937495 Common - iron dependent repressor Igni_0702 82 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 156937160 Nonpathogen - DNA-directed RNA polymerase, subunit M Igni_0366 7 COG1594 RPB9, DNA-directed RNA polymerase, subunit M/Transcription elongation factor TFIIS Transcription 156937002 Nonpathogen - hypothetical protein Igni_0207 7 COG2014 COG2014, Uncharacterized conserved protein Function unknown 156937640 Nonpathogen - hypothetical protein Igni_0847 1 None None None 156937303 Nonpathogen - translation elongation factor 1B (aEF-1B) Igni_0509 10 COG2092 EFB1, Translation elongation factor EF-1beta Translation, ribosomal structure and biogenesis 156937653 Nonpathogen - SSU ribosomal protein S15P Igni_0860 34 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 156937082 Nonpathogen - translation initiation factor 6 (aeIF-6) Igni_0288 33 COG1976 TIF6, Translation initiation factor 6 (eIF-6) Translation, ribosomal structure and biogenesis 156938227 Nonpathogen - membrane-bound metal-dependent hydrolase Igni_1440 4 COG1988 COG1988, Predicted membrane-bound metal-dependent hydrolases General function prediction only 156938213 Nonpathogen - transcriptional regulator, ArsR family Igni_1426 5 COG2345 COG2345, Predicted transcriptional regulator Transcription 156936971 Nonpathogen - hypothetical protein Igni_0176 5 None None None 156936803 Nonpathogen - hypothetical protein Igni_0008 1 None None None 156937928 Nonpathogen - CRISPR-associated autoregulator, DevR family Igni_1140 14 COG1857 COG1857, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 156937418 Nonpathogen - hypothetical protein Igni_0625 1 None None None