Campylobacter curvus 525.92, complete genome NC_009715 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 154175387 Common - ferredoxin-type protein, NapH/MauN family CCV52592_1930 63 COG0348 NapH, Polyferredoxin Energy production and conversion 154174777 Common - putative molybdopterin-guanine dinucleotide biosynthesis protein CCV52592_0609 48 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 154174633 Common glyQ glycyl-tRNA synthetase, alpha subunit CCV52592_0284 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 154174218 Common rpsG ribosomal protein S7 CCV52592_0187 218 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 154174871 Common - L-lactate dehydrogenase (cytochrome) CCV52592_0468 111 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 154173994 Common - tetratricopeptide repeat domain protein CCV52592_1515 6 None None None 154173881 Common - acriflavine resistance protein B CCV52592_1775 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 154174013 Common ruvB holliday junction DNA helicase RuvB CCV52592_1922 226 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 154174398 Pathogen - hypothetical protein CCV52592_0301 1 None None None 154174463 Common - nitrous oxidase accessory protein CCV52592_0007 52 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 154174043 Common - phage Gp37Gp68 family protein CCV52592_1598 42 COG4422 COG4422, Bacteriophage protein gp37 Function unknown 154174050 Common - hemin transport system permease protein HmuU CCV52592_0650 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 154174288 Common - hypothetical protein CCV52592_1041 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154173868 Common - sulfur reductase FeS subunit CCV52592_1915 166 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 154174829 Common - hypothetical protein CCV52592_1352 1 COG3147 DedD, Uncharacterized protein conserved in bacteria Function unknown 154174281 Common purS phosphoribosylformylglycinamidine synthase, PurS protein CCV52592_2004 114 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 154173764 Common - hypothetical protein CCV52592_1596 4 None None None 154174940 Pathogen - hypothetical protein CCV52592_0380 1 None None None 154175509 Common - hypothetical protein CCV52592_1435 62 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 154174933 Common gltX glutamyl-tRNA synthetase CCV52592_0438 247 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 154175084 Common - multi-sensor signal transduction histidine kinase CCV52592_0542 6 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 154174458 Common - hypothetical protein CCV52592_1832 7 COG1847 Jag, Predicted RNA-binding protein General function prediction only 154174930 Common - cupin 2, conserved barrel CCV52592_2020 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 154175170 Common ribF riboflavin biosynthesis protein RibF CCV52592_1563 211 COG0196 RibF, FAD synthase Coenzyme metabolism 154174870 Pathogen - hypothetical protein CCV52592_1171 1 None None None 154175435 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA(Glucose-inhibited division protein A) CCV52592_0431 17 COG4393 COG4393, Predicted membrane protein Function unknown 154174129 Common - hypothetical protein CCV52592_0624 86 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 154174953 Common - ferrochelatase (Protoheme ferro-lyase) (Hemesynthetase) CCV52592_0446 7 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 154175229 Common relA GTP pyrophosphokinase CCV52592_1190 5 None None None 154174644 Pathogen - hypothetical protein CCV52592_0771 1 None None None 154174787 Common - hypothetical protein CCV52592_2099 1 None None None 154174120 Common - hypothetical protein CCV52592_0572 37 COG0622 COG0622, Predicted phosphoesterase General function prediction only 154174352 Pathogen - citrate transporter superfamily CCV52592_1711 1 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 154174102 Common accD acetyl-CoA carboxylase, carboxyl transferase, beta subunit CCV52592_1756 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 154174607 Common grpE co-chaperone GrpE CCV52592_0150 232 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 154175253 Common nuoL hydrogenase 4 membrane subunit CCV52592_0429 44 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 154175007 Common - putative transcriptional regulator superfamily CCV52592_1769 145 COG1733 COG1733, Predicted transcriptional regulators Transcription 154173857 Common purB adenylosuccinate lyase CCV52592_1121 239 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 154174573 Common - OorD subunit of 2-oxoglutarate:acceptor oxidoreductase CCV52592_1880 38 COG1146 COG1146, Ferredoxin Energy production and conversion 154175380 Common atpB ATP synthase F0, A subunit CCV52592_0790 183 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 154174134 Common - exodeoxyribonuclease 7 small subunit (Exodeoxyribonuclease VII small subunit) (Exonuclease VII smallsubunit) CCV52592_0981 3 None None None 154174251 Common - type I secretion membrane fusion protein, HlyD CCV52592_0164 138 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154174912 Common - mate efflux family protein CCV52592_0078 171 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 154174949 Common - putative lipoprotein CCV52592_0021 2 None None None 154174225 Common - hypothetical protein CCV52592_0772 6 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 154174161 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase CCV52592_0516 230 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 154174323 Common rpsC ribosomal protein S3 CCV52592_1027 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 154174842 Common - hydroxylamine oxidase CCV52592_0434 19 None None None 154174942 Common - aspartyl/glutamyl-tRNA(Asn/Gln) amidotransferase subunit B (Asp/Glu-ADT subunit B) CCV52592_0791 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 154174885 Common - biotin/lipoyl attachment CCV52592_0964 185 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 154174179 Common metW methionine biosynthesis protein MetW CCV52592_0299 45 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 154174088 Common - aspartate racemase CCV52592_1766 83 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 154174346 Common leuB 3-isopropylmalate dehydrogenase CCV52592_1365 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 154175184 Common def peptide deformylase CCV52592_1501 213 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 154173935 Common - toxin secretion ATP-binding protein CCV52592_0163 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 154175271 Common - WbnF CCV52592_1845 90 None None None 154174236 Pathogen - hypothetical protein CCV52592_2133 1 None None None 154174782 Common - trap dicarboxylate transporter- dctp subunit CCV52592_0633 97 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 154175353 Common - elongation factor Tu (EF-Tu) CCV52592_1523 182 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 154175236 Common ruvC crossover junction endodeoxyribonuclease RuvC CCV52592_2057 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 154173715 Common rpsI ribosomal protein S9 CCV52592_0912 246 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 154174387 Pathogen - hypothetical protein CCV52592_1304 1 None None None 154174145 Common secD protein-export membrane protein SecD CCV52592_0707 218 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 154173745 Common glmS glutamine-fructose-6-phosphate transaminase (isomerizing) CCV52592_0218 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 154174244 Common folK 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CCV52592_0366 169 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 154175331 Pathogen - peptide deformylase (PDF) (Polypeptide deformylase) CCV52592_1339 1 None None None 154175371 Common - ribosome-binding factor A CCV52592_1803 131 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 154174048 Common cas crispr-associated protein Cas1 CCV52592_1287 85 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 154173963 Common ppa inorganic diphosphatase CCV52592_0470 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 154175124 Common - aminoacyl-histidine dipeptidase CCV52592_0737 5 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 154175070 Common murC UDP-N-acetylmuramate--alanine ligase CCV52592_0985 207 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 154174514 Common hisF imidazoleglycerol phosphate synthase, cyclase subunit CCV52592_1117 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 154175231 Common - putative periplasmic protein CCV52592_0713 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 154175441 Common trpA tryptophan synthase, alpha subunit CCV52592_1687 214 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 154173875 Common - MmgE/PrpD family CCV52592_0206 62 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 154174309 Common - oxidoreductase domain protein CCV52592_0878 182 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 154175514 Pathogen - glutathionylspermidine synthase family protein CCV52592_2125 1 None None None 154174502 Common lysA diaminopimelate decarboxylase CCV52592_1665 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 154175482 Common - lipoprotein-releasing system ATP-binding protein LolD CCV52592_0077 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 154175408 Common - bacterial flagellin protein CCV52592_0568 113 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 154175207 Common - glycosysltransferase CCV52592_1856 58 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 154174331 Common - NADPH-flavin oxidoreductase CCV52592_1605 108 COG0778 NfnB, Nitroreductase Energy production and conversion 154175267 Common - S1 RNA binding domain protein CCV52592_0514 223 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 154173813 Common - stage 0 sporulation protein J CCV52592_1732 183 COG1475 Spo0J, Predicted transcriptional regulators Transcription 154175260 Common - hypothetical protein CCV52592_1457 1 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 154173945 Common cydB cytochrome D ubiquinol oxidase, subunit II CCV52592_2080 138 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 154174897 Common - hypothetical protein CCV52592_0937 5 None None None 154175096 Common rplK ribosomal protein L11 CCV52592_0177 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 154174485 Common - NnrS protein CCV52592_0640 27 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 154173640 Common - putative CAP-Gly domain containing protein CCV52592_0054 3 None None None 154174038 Common - arabinose 5-phosphate isomerase CCV52592_1114 148 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 154173647 Common hypC hydrogenase assembly chaperone HypC/HupF CCV52592_1892 89 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 154173988 Common - cell division protein FtsX CCV52592_0479 16 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 154173959 Common serB phosphoserine phosphatase SerB CCV52592_1659 154 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 154174509 Pathogen - hypothetical protein CCV52592_1286 1 None None None 154174776 Common - ABC transporter membrane-spanning permease - glutamine transport CCV52592_0287 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 154174597 Common - periplasmic protein CCV52592_0161 32 COG3672 COG3672, Predicted periplasmic protein Function unknown 154175296 Common - putative bacterial sugar transferase CCV52592_1211 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 154174338 Common hisB imidazoleglycerol-phosphate dehydratase CCV52592_0457 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 154175359 Common gltA citrate (Si)-synthase CCV52592_0576 194 COG0372 GltA, Citrate synthase Energy production and conversion 154174920 Common alr alanine racemase CCV52592_1338 195 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 154173952 Common - putative integral membrane protein CCV52592_0223 7 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 154174007 Common - 50S ribosomal protein L5 (BL6) CCV52592_1021 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 154175395 Common - hypothetical protein CCV52592_1619 81 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 154173802 Common - transformation system protein CCV52592_1458 9 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 154175489 Common - transcriptional regulator, LysR family CCV52592_1779 41 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 154174681 Pathogen - hypothetical protein CCV52592_2083 1 None None None 154174625 Common pgi glucose-6-phosphate isomerase CCV52592_2200 210 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 154175401 Common - O-acetylhomoserine (thiol)-lyase CCV52592_1597 42 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 154174081 Common - zinc protease CCV52592_1251 86 COG2321 COG2321, Predicted metalloprotease General function prediction only 154173896 Common - magnesium and cobalt efflux protein CorC CCV52592_0644 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 154174430 Common rpsU ribosomal protein S21 CCV52592_1544 81 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 154174477 Common trxB thioredoxin-disulfide reductase CCV52592_0838 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 154175276 Common - malic enzyme, NAD binding domain protein CCV52592_0547 201 COG0281 SfcA, Malic enzyme Energy production and conversion 154174799 Common - TM2 CCV52592_0744 7 COG2314 XynA, Predicted membrane protein Function unknown 154174814 Common ilvE branched-chain amino acid aminotransferase CCV52592_0855 212 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 154174719 Pathogen - hypothetical protein CCV52592_1960 1 None None None 154173714 Pathogen - 13S globulin CCV52592_0525 1 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 154174610 Common purQ phosphoribosylformylglycinamidine synthase I CCV52592_2003 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 154173695 Common - hypothetical protein CCV52592_0530 2 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 154173690 Common - macrolide export ATP-binding/permease protein MacB CCV52592_1085 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 154175118 Pathogen - putative cytochrome c family protein CCV52592_0545 1 None None None 154173791 Common - flagellar assembly factor FliW CCV52592_1592 14 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 154175119 Common rho transcription termination factor CCV52592_0861 45 None None None 154174009 Pathogen - hypothetical protein CCV52592_1572 1 None None None 154173761 Common - hypothetical protein CCV52592_1329 5 None None None 154174581 Common cysK cysteine synthase A CCV52592_0717 227 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 154175028 Pathogen mpr ATP-binding protein CCV52592_1773 1 None None None 154175122 Common - putative YgbB family CCV52592_0202 192 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 154174794 Common ftsZ cell division protein FtsZ CCV52592_1843 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 154175044 Common - Tat (twin-arginine translocation) pathway signal sequence domain protein CCV52592_0264 69 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 154173635 Common csrA carbon storage regulator CCV52592_0697 4 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 154174808 Common - ATP-dependent DNA helicase, UvrD/REP family CCV52592_0910 228 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 154173783 Common recA protein RecA CCV52592_0616 237 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 154174095 Common astC succinylornithine transaminase CCV52592_1387 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 154175129 Common - outer membrane protein transport protein (OMPP1/FadL/TodX) CCV52592_1488 71 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 154174534 Common - 2-acyl-glycerophospho-ethanolamine acyltransferase CCV52592_0888 227 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154175545 Common - heavy metal translocating P-type ATPase subfamily CCV52592_1377 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154175198 Common - phosphoglucomutase/phosphomannomutase, C- domain family CCV52592_0306 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 154174108 Common atpG ATP synthase F1, gamma subunit CCV52592_1737 207 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 154175548 Common - hypothetical protein CCV52592_1546 185 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 154173957 Common radA DNA repair protein RadA CCV52592_1392 205 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 154173775 Common - hypothetical protein CCV52592_0214 1 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 154175432 Common - putative integral membrane protein CCV52592_1194 145 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 154174693 Common flhA flagellar biosynthesis protein FlhA CCV52592_1553 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 154174663 Common - putative cytochrome c family protein CCV52592_0196 1 COG2863 COG2863, Cytochrome c553 Energy production and conversion 154173906 Common - putative 6-pyruvoyl tetrahydrobiopterin synthase (ptps)(ptp synthase) CCV52592_0824 28 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 154174325 Common - polyphosphate kinase 2 CCV52592_0147 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 154175247 Common rnhA RNase H CCV52592_2066 175 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 154174973 Common - thiazole biosynthesis protein ThiG CCV52592_0606 13 None None None 154174812 Common patB aminotransferase, class II CCV52592_1001 216 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 154173978 Common - putative periplasmic protein CCV52592_1632 9 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 154173950 Common - hypothetical protein CCV52592_0503 5 None None None 154175073 Common - putative phospholipid-binding domain family CCV52592_0589 18 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 154174750 Common carA carbamoyl-phosphate synthase, small subunit CCV52592_0898 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 154174563 Common - thioester dehydrase family protein CCV52592_1165 22 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 154175023 Common - general glycosylation pathway protein CCV52592_0758 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 154173961 Pathogen - hypothetical protein CCV52592_0167 1 None None None 154174823 Common - acyl carrier protein CCV52592_0968 46 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154174635 Common mscL large conductance mechanosensitive channel protein CCV52592_0437 144 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 154175373 Common ribA GTP cyclohydrolase II CCV52592_1346 176 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 154173911 Common - stas domain protein CCV52592_1433 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 154175143 Common - hypothetical protein CCV52592_0759 1 None None None 154174659 Pathogen - hypothetical protein CCV52592_0860 1 None None None 154173618 Common - hypothetical protein CCV52592_0059 8 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 154175461 Common - DedA family protein CCV52592_1876 65 COG0716 FldA, Flavodoxins Energy production and conversion 154175212 Common - hypothetical protein CCV52592_0614 7 None None None 154174022 Pathogen - hypothetical protein CCV52592_0751 4 None None None 154174468 Common rpsE ribosomal protein S5 CCV52592_1016 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 154174988 Pathogen - acetyltransferase CCV52592_1905 1 None None None 154173642 Common purA adenylosuccinate synthetase CCV52592_1784 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 154174437 Common - putative soluble lytic murein transglycosylase CCV52592_0440 80 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 154173790 Pathogen - hypothetical protein CCV52592_0278 1 None None None 154174650 Common - heat-inducible transcription repressor CCV52592_0151 37 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 154174000 Common - serine 3-dehydrogenase CCV52592_1706 127 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 154173649 Common eno phosphopyruvate hydratase CCV52592_0615 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 154175365 Pathogen - outer membrane autotransporter barrel domain protein CCV52592_1252 1 None None None 154175323 Common pmi mannose-6-phosphate isomerase CCV52592_0879 203 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 154173673 Common - hypothetical protein CCV52592_0444 6 None None None 154175306 Common - dihydrouridine synthase (Dus) superfamily CCV52592_1752 211 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 154173820 Common rpsO ribosomal protein S15 CCV52592_1555 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 154174262 Pathogen - hypothetical protein CCV52592_1373 1 None None None 154174069 Common - hypothetical protein CCV52592_1969 2 None None None 154174730 Common - ABC-type Co2+ transport system, periplasmic component CCV52592_0558 17 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 154175526 Common - cyclic diguanylate phosphodiesterase (EAL) domain protein CCV52592_1647 176 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 154174677 Common - putative vesicular transport factor Uso1p CCV52592_1948 132 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 154174426 Pathogen - hypothetical protein CCV52592_0216 1 None None None 154174571 Common rpmI ribosomal protein L35 CCV52592_0346 126 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 154173827 Common - diamine acetyltransferase 2 CCV52592_2131 97 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 154175101 Common - integral membrane protein DUF6 CCV52592_1276 23 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 154175497 Common - phosphoglycerate mutase family protein CCV52592_1088 45 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 154174057 Common - methyltransferase domain family CCV52592_0599 38 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 154175454 Pathogen - transmembrane transport protein CCV52592_1302 1 None None None 154175300 Pathogen - thiamine-phosphate pyrophosphorylase (TMPpyrophosphorylase) (TMP-PPase) (Thiamine-phosphate synthase) CCV52592_2068 1 None None None 154174375 Common - transmembrane transport protein CCV52592_0654 62 COG1133 SbmA, ABC-type long-chain fatty acid transport system, fused permease and ATPase components Lipid metabolism 154175417 Pathogen - prokaryotic N- methylation motif domain protein CCV52592_1594 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 154173733 Pathogen - hypothetical protein CCV52592_0026 1 None None None 154175161 Common proC pyrroline-5-carboxylate reductase CCV52592_1603 22 COG4099 COG4099, Predicted peptidase General function prediction only 154175269 Common nikA nickel ABC transporter, periplasmic nickel-binding protein CCV52592_1321 205 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 154174623 Common - acyltransferase CCV52592_1175 37 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 154173627 Common - D-alanine--D-alanine ligase (D-alanylalanine synthetase)(D-Ala-D-Ala ligase) CCV52592_1152 208 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 154174270 Pathogen - hypothetical protein CCV52592_2141 1 None None None 154174231 Pathogen - hypothetical protein CCV52592_0935 1 None None None 154173888 Common nhaA Na+/H+ antiporter NhaA CCV52592_1896 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 154175407 Common cooS carbon-monoxide dehydrogenase, catalytic subunit CCV52592_1131 25 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 154175168 Common - protein translation intiation inhibitor CCV52592_0805 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 154173656 Common - anaerobic ribonucleoside-triphosphate reductase CCV52592_0019 21 None None None 154174854 Common - hypothetical protein CCV52592_1970 4 None None None 154173841 Common - hypothetical protein CCV52592_0341 7 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 154175533 Common - 2-isopropylmalate synthase (Alpha-isopropylmalatesynthase) (Alpha-IPM synthetase) CCV52592_0766 1 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 154173866 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase CCV52592_1442 217 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 154174737 Common - flagellar protein FlaG CCV52592_0779 9 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 154173914 Common - transcriptional regulator, ModE family CCV52592_0738 58 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 154174170 Common rpsD ribosomal protein S4 CCV52592_1009 247 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 154175490 Common - transporter, lactate permease (LctP) family CCV52592_0467 105 COG1620 LldP, L-lactate permease Energy production and conversion 154174907 Common - hypothetical protein CCV52592_0426 1 None None None 154175186 Common - putative methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor CCV52592_0663 8 None None None 154175427 Common - radical SAM enzyme, Cfr family CCV52592_1119 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 154174073 Common - alpha/beta hydrolase fold CCV52592_1173 65 COG2267 PldB, Lysophospholipase Lipid metabolism 154174015 Pathogen - hypothetical protein CCV52592_0020 1 None None None 154173681 Common - MacA CCV52592_1084 172 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154175057 Common gap glyceraldehyde-3-phosphate dehydrogenase, type I CCV52592_1249 222 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 154175355 Common - saccharopine dehydrogenase CCV52592_1257 8 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 154174300 Common - Mur ligase family protein CCV52592_1156 182 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 154173722 Common - NADH-dependent flavin oxidoreductase CCV52592_2060 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 154174567 Common - hypothetical protein CCV52592_1469 25 COG2862 COG2862, Predicted membrane protein Function unknown 154174060 Pathogen - hypothetical protein CCV52592_0031 1 None None None 154174990 Common - putative endoribonuclease L-PSP CCV52592_0631 187 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 154175173 Common - general stress protein 14 (GSP14) CCV52592_1153 1 None None None 154174989 Common - hypothetical protein CCV52592_1328 62 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 154174416 Common - N- methylation CCV52592_0224 6 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 154174174 Common - NADH:ubiquinone oxidoreductase, na CCV52592_2199 17 COG3738 COG3738, Uncharacterized protein conserved in bacteria Function unknown 154174296 Common - putative tetraheme cytochrome c CCV52592_0435 39 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 154174153 Common - hypothetical protein CCV52592_0120 3 None None None 154175154 Common nusA transcription termination factor NusA CCV52592_0262 221 COG0195 NusA, Transcription elongation factor Transcription 154174291 Common - signaling protein CCV52592_2120 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 154173932 Common - putative conserved hypothetical protein CCV52592_1940 9 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 154174868 Common - general stress protein 14 (GSP14) CCV52592_1006 72 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 154173729 Common - hypothetical protein CCV52592_0987 3 None None None 154173976 Pathogen - hypothetical protein CCV52592_0768 1 None None None 154174267 Common argB acetylglutamate kinase CCV52592_0128 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 154174435 Common rpmC ribosomal protein L29 CCV52592_1025 12 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 154175005 Pathogen - hypothetical protein CCV52592_1123 1 None None None 154174575 Common - TonB family C- domain protein CCV52592_2219 3 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 154175259 Common - S-adenosyl-L-methionine-dependent methyltransferase MraW CCV52592_0586 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 154173637 Common pth peptidyl-tRNA hydrolase CCV52592_1663 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 154175227 Common - purine nucleoside phosphorylase CCV52592_0592 9 COG3608 COG3608, Predicted deacylase General function prediction only 154174982 Common - peptidase, M48 family CCV52592_1820 84 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 154173999 Common - formate/nitrite transporter CCV52592_1640 79 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 154175347 Common typA GTP-binding protein TypA/BipA CCV52592_2046 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 154174688 Common - hypothetical protein CCV52592_0859 17 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 154174045 Common - alpha-2-macroglobulin family N- region CCV52592_1077 70 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 154174609 Common rplW ribosomal protein L23 CCV52592_1030 68 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 154174136 Common - integral membrane protein CCV52592_1410 44 COG2510 COG2510, Predicted membrane protein Function unknown 154174919 Pathogen - putative periplasmic protein CCV52592_1857 1 None None None 154175340 Pathogen napB periplasmic nitrate reductase CCV52592_0009 1 None None None 154175091 Common - phosphohistidine phosphatase SixA CCV52592_1894 10 COG4929 COG4929, Uncharacterized membrane-anchored protein Function unknown 154175363 Common - seryl-tRNA synthetase (Serine--tRNA ligase) (SerRS) CCV52592_0770 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 154173855 Common - ribosomal large subunit pseudouridine synthase D CCV52592_0474 214 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 154173811 Common - TonB-dependent outer membrane receptor CCV52592_0604 124 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 154174830 Common rpsR ribosomal protein S18 CCV52592_1587 118 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 154174246 Pathogen - hypothetical protein CCV52592_1367 1 None None None 154174883 Common - prephenate dehydrogenase CCV52592_2225 163 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 154174955 Common - ribonuclease HII (RNase HII) CCV52592_0405 24 COG4866 COG4866, Uncharacterized conserved protein Function unknown 154175010 Common - protein CysQ CCV52592_1336 101 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 154175321 Common - diaminopimelate epimerase (DAP epimerase) CCV52592_1811 98 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 154175146 Common - phosphoglycerate kinase CCV52592_1824 43 COG2966 COG2966, Uncharacterized conserved protein Function unknown 154174275 Common - Omp18 CCV52592_1744 147 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 154174766 Pathogen - hypothetical protein CCV52592_1234 1 None None None 154173818 Common - putative phosphoglycerol transferase CCV52592_0769 28 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 154173992 Common - putative bifunctional protein: sulfite reductase [NADPH] flavoprotein alpha-component; iron-uptake factor CCV52592_2094 20 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 154175082 Common - metallo-beta-lactamase family protein CCV52592_1991 223 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 154174705 Common mobB molybdopterin-guanine dinucleotide biosynthesis protein B CCV52592_0442 91 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 154175448 Common - arginine biosynthesis bifunctional protein ArgJ CCV52592_1326 7 None None None 154174748 Pathogen - hypothetical protein CCV52592_1704 1 None None None 154175351 Common - hypothetical protein CCV52592_1450 7 None None None 154174147 Pathogen - hypothetical protein CCV52592_0747 2 None None None 154174844 Common - diguanylate cyclase CCV52592_0712 180 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 154174253 Common - hypothetical protein CCV52592_1995 9 None None None 154175250 Common - orotate phosphoribosyltransferase (oprt) (oprtase) CCV52592_2073 24 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 154174205 Common - glycosyltransferase involved in cell wall biogenesis CCV52592_0338 173 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 154173986 Common - lipoprotein-releasing system ATP-binding protein LolD CCV52592_1259 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 154174585 Common - N- methylation CCV52592_0320 20 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 154174479 Common - oxidoreductase CCV52592_1947 86 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 154174599 Common dprA DNA protecting protein DprA CCV52592_1579 208 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 154174595 Pathogen - hypothetical protein CCV52592_2127 1 None None None 154174500 Common - recombination and DNA strand exchange inhibitor protein CCV52592_0988 161 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 154173971 Common - domain protein CCV52592_1386 133 COG2860 COG2860, Predicted membrane protein Function unknown 154174185 Common - UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase CCV52592_1002 212 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 154174545 Common - transcriptional regulator, BadM/Rrf2 family CCV52592_1554 34 COG1959 COG1959, Predicted transcriptional regulator Transcription 154174396 Common aroB 3-dehydroquinate synthase CCV52592_1438 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 154174354 Common - flavodoxin CCV52592_0376 69 COG0716 FldA, Flavodoxins Energy production and conversion 154174052 Common mrr Mrr restriction system protein CCV52592_0753 48 COG1715 Mrr, Restriction endonuclease Defense mechanisms 154174113 Pathogen - hypothetical protein CCV52592_0029 3 None None None 154174077 Common - hypothetical protein CCV52592_0318 3 None None None 154174168 Common - TolC protein CCV52592_1086 109 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154174931 Common - glycosyl hydrolase, family 57 CCV52592_2112 84 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 154174213 Common - general glycosylation pathway protein CCV52592_1217 156 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 154174283 Common - glycosyl transferase, group 1 family protein CCV52592_0297 182 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154173630 Common - PDZ domain protein CCV52592_0072 10 None None None 154173725 Common lon ATP-dependent protease La CCV52592_1589 229 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 154173886 Common rbfA ribosome-binding factor A CCV52592_0356 8 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 154174665 Common - CoA-binding domain protein CCV52592_1421 154 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 154174818 Common metX homoserine O-acetyltransferase CCV52592_0980 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 154173625 Common - cytoplasmic membrane protein CCV52592_1132 99 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 154174031 Common - lipolytic enzyme CCV52592_1534 128 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154175094 Common recG ATP-dependent DNA helicase RecG CCV52592_0367 227 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 154173890 Pathogen - hypothetical protein CCV52592_0639 1 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 154174654 Pathogen - hypothetical protein CCV52592_1301 1 None None None 154173947 Common - C4-dicarboxylate-binding periplasmic protein CCV52592_2123 118 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 154173770 Common - hypothetical protein CCV52592_0198 2 None None None 154174837 Common - hypothetical protein CCV52592_0168 28 COG3672 COG3672, Predicted periplasmic protein Function unknown 154174507 Common - HmuU protein CCV52592_0813 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 154175131 Pathogen - hypothetical protein CCV52592_0192 1 None None None 154175393 Common - putative amidase CCV52592_0978 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 154173872 Pathogen - hypothetical protein CCV52592_1306 1 None None None 154174036 Common rplD ribosomal protein L4/L1 family CCV52592_1031 217 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 154174336 Common - hypothetical protein CCV52592_0504 9 None None None 154174214 Common - snare associated golgi protein CCV52592_0339 45 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 154173899 Common - 2-hydroxyglutaryl-CoA dehydratase, D-component CCV52592_0873 39 COG1775 HgdB, Benzoyl-CoA reductase/2-hydroxyglutaryl-CoA dehydratase subunit, BcrC/BadD/HgdB Amino acid transport and metabolism 154173831 Common - fkbp-type peptidyl-prolyl cis-trans isomerase slyd (ppiase) (rotamase) CCV52592_1746 129 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 154175450 Common pepT peptidase T CCV52592_2074 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 154173804 Pathogen - hypothetical protein CCV52592_0319 1 None None None 154175294 Pathogen - signal-transduction sensor protein-pas/pac domain CCV52592_0041 1 None None None 154174517 Common - type II secretion system protein CCV52592_1963 145 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 154175190 Common - NAD dependent epimerase/dehydratase family CCV52592_1226 232 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154175385 Common moeB molybdopterin biosynthesis protein MoeB CCV52592_0605 3 None None None 154174945 Common - colicin I receptor CCV52592_1978 86 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 154174373 Common - putative undecaprenol kinase CCV52592_0067 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 154173965 Common - transporter CCV52592_0081 131 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 154174028 Common - acyl-CoA thioester hydrolase YciA CCV52592_1642 113 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 154175328 Common - lactate/malate dehydrogenase, NAD binding domain protein CCV52592_1883 165 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 154175474 Pathogen - hypothetical protein CCV52592_0897 1 None None None 154174895 Common - hypothetical protein CCV52592_0812 41 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 154174774 Common - oxidoreductase with FAD/NAD CCV52592_0409 135 COG2081 COG2081, Predicted flavoproteins General function prediction only 154175443 Common - HsdS CCV52592_1637 192 COG3260 COG3260, Ni,Fe-hydrogenase III small subunit Energy production and conversion 154174344 Common - superoxide dismutase (Fe) CCV52592_1312 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 154175399 Common nrdD anaerobic ribonucleoside-triphosphate reductase CCV52592_1124 105 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 154174516 Common - yggt family protein CCV52592_0439 38 COG0762 COG0762, Predicted integral membrane protein Function unknown 154174494 Common - aconitate hydratase 2 (Citrate hydro-lyase 2) (Aconitase2) CCV52592_1414 220 COG1049 AcnB, Aconitase B Energy production and conversion 154174944 Common - fumarate reductase flavoprotein subunit CCV52592_2205 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 154175283 Common - protein EbsC CCV52592_0275 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 154174789 Common serS seryl-tRNA synthetase CCV52592_1189 245 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 154173701 Common - biotin synthase (Biotin synthetase) CCV52592_0574 172 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 154174194 Common - hypothetical protein CCV52592_0220 86 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 154173937 Common nifJ pyruvate:ferredoxin (flavodoxin) oxidoreductase CCV52592_0916 122 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 154175038 Common - Na(+)/H(+) antiporter 1 (Sodium/proton antiporter 1) CCV52592_0641 36 COG3315 COG3315, O-Methyltransferase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 154175068 Common - antioxidant, AhpC/TSA family CCV52592_0858 223 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 154175512 Common - phosphoribosylformylglycinamidine cyclo-ligase CCV52592_1808 4 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 154173756 Common - general glycosylation pathway protein CCV52592_1201 10 None None None 154174063 Common - ribosomal protein L25, Ctc-form CCV52592_1662 143 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 154174368 Common hemC porphobilinogen deaminase CCV52592_0767 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 154175531 Pathogen - pantoate--beta-alanine ligase (Pantothenate synthetase)(Pantoate-activating enzyme) CCV52592_0840 1 None None None 154173712 Common - sulfate/thiosulfate import ATP-binding protein CysA (Sulfate-transporting ATPase) CCV52592_0582 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 154175021 Common - divergent polysaccharide deacetylase family CCV52592_1580 54 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 154173926 Pathogen - hypothetical protein CCV52592_1413 1 None None None 154174971 Common - deoxyribonuclease, TatD family CCV52592_1212 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154173661 Common fliE flagellar hook-basal body complex protein (FliE) CCV52592_0691 44 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 154174483 Common - hypothetical protein CCV52592_0384 8 COG1598 COG1598, Uncharacterized conserved protein Function unknown 154174561 Common - ribonucleoside-diphosphate reductase, alpha subunit CCV52592_1122 217 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 154175468 Common - hypothetical protein CCV52592_0510 3 None None None 154175375 Pathogen rplM ribosomal protein L13 CCV52592_1416 1 None None None 154174551 Common - oxidoreductase family, NAD-binding Rossmann fold protein CCV52592_0687 39 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 154174401 Common - chaperonin CCV52592_1183 5 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 154175188 Common - hypothetical protein CCV52592_1398 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 154175422 Common - oxygen-independent coproporphyrinogen III oxidase CCV52592_0372 204 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 154173719 Common - ATPase CCV52592_0500 12 None None None 154174600 Common - thioredoxin family protein CCV52592_0427 20 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 154175285 Common dcd deoxycytidine triphosphate deaminase CCV52592_0933 170 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 154173785 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase (KDO 8-P phosphatase) CCV52592_0456 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 154174327 Common - protein YajQ CCV52592_1539 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 154175456 Pathogen - IroE protein CCV52592_0057 1 None None None 154174381 Pathogen - hypothetical protein CCV52592_0022 1 None None None 154174094 Pathogen - hypothetical protein CCV52592_0311 1 None None None 154174114 Common - oxidoreductase, 2-nitropropane dioxygenase family CCV52592_0485 125 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 154175463 Pathogen - molybdenum cofactor biosynthesis protein A CCV52592_0140 1 None None None 154174071 Common modA molybdate ABC transporter, periplasmic molybdate-binding protein CCV52592_0553 60 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 154175510 Common panB 3-methyl-2-oxobutanoate hydroxymethyltransferase CCV52592_1923 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 154174652 Common moaA molybdenum cofactor biosynthesis protein A CCV52592_0822 197 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 154174619 Common - mate efflux family protein CCV52592_1507 170 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 154173688 Common - trap-type mannitol/chloroaromatic compound transport system, periplasmic component CCV52592_1354 98 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 154174866 Common - Hit family protein CCV52592_1953 104 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 154174183 Common - sensor histidine kinase CCV52592_0501 181 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154173939 Pathogen - hypothetical protein CCV52592_2148 1 None None None 154174724 Common - hypothetical protein CCV52592_1376 3 None None None 154174593 Common - ferric uptake regulation protein CCV52592_2147 201 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 154174453 Common - ATPase, ParA family CCV52592_0368 242 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 154175066 Common - hypothetical protein CCV52592_1996 16 None None None 154175493 Common - transcription elongation factor GreA (Transcript cleavage factorgreA) CCV52592_1740 142 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 154175112 Common - MTA/SAH nucleosidase CCV52592_1786 15 COG3334 COG3334, Uncharacterized conserved protein Function unknown 154174894 Common lysS lysyl-tRNA synthetase CCV52592_1349 245 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 154174177 Common - putative ABC transporter ATP-binding protein CCV52592_0401 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 154174757 Common - hypothetical protein CCV52592_0831 5 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 154174269 Common pyrF orotidine 5'-phosphate decarboxylase CCV52592_1179 167 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 154175059 Common dfp pantothenate metabolism flavoprotein CCV52592_0084 213 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 154175314 Common - hypothetical protein CCV52592_0670 5 COG2863 COG2863, Cytochrome c553 Energy production and conversion 154174199 Common - ABC transporter, permease protein, FecCD family CCV52592_0602 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 154174260 Common - flavodoxin CCV52592_1956 30 COG0716 FldA, Flavodoxins Energy production and conversion 154173869 Common - two component transcriptional regulator, winged helix family CCV52592_0851 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154173693 Common - ATPase with chaperone activity, ATP-binding domain, diverged CCV52592_0715 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 154173654 Common - putative Mg chelatase-like protein CCV52592_1502 190 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 154174021 Common psd phosphatidylserine decarboxylase CCV52592_1195 41 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 154173870 Common dxr 1-deoxy-D-xylulose 5-phosphate reductoisomerase CCV52592_0594 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 154173704 Common - histidine kinase CCV52592_1692 175 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154175278 Common - hypothetical protein CCV52592_0073 52 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 154174521 Common - hypothetical protein CCV52592_0028 5 None None None 154175543 Pathogen - lipid A biosynthesis acyltransferase CCV52592_2171 1 None None None 154175042 Common - hypothetical protein CCV52592_0200 51 COG2046 MET3, ATP sulfurylase (sulfate adenylyltransferase) Inorganic ion transport and metabolism 154173903 Common - hypothetical protein CCV52592_1599 14 None None None 154173731 Common - hypothetical protein CCV52592_2050 3 COG3399 COG3399, Uncharacterized protein conserved in bacteria Function unknown 154174393 Pathogen - hypothetical protein CCV52592_2077 1 None None None 154174797 Common - radical SAM domain protein CCV52592_1472 51 COG0731 COG0731, Fe-S oxidoreductases Energy production and conversion 154174536 Common - hypothetical protein CCV52592_1651 14 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 154173838 Common - hypothetical protein CCV52592_0893 2 None None None 154174806 Common purH bifunctional purine biosynthesis protein PurH CCV52592_1838 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 154175072 Common - fumarate hydratase class II (Fumarase C) CCV52592_0433 49 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 154174588 Common - hypothetical protein CCV52592_0451 2 None None None 154174121 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase CCV52592_0967 45 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 154174272 Common - dihydroorotase (DHOase) CCV52592_0154 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 154175507 Common iadA beta-aspartyl peptidase CCV52592_0185 22 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 154174628 Common - L-fuculose-1-phosphate aldolase CCV52592_1846 7 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 154174921 Common - type III effector HopAH2-2 CCV52592_0088 63 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 154174311 Common mraW S-adenosyl-methyltransferase MraW CCV52592_1847 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 154174342 Common - iron compounds ABC transporter, ATP-binding protein CCV52592_1615 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 154174172 Common - hypothetical protein CCV52592_1441 137 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 154174359 Common glmU UDP-N-acetylglucosamine diphosphorylase/glucosamine-1-phosphate N-acetyltransferase CCV52592_1268 229 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 154173916 Common - anaerobic C4-dicarboxylate transporter DcuA CCV52592_0209 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 154175471 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase (Polyprenylp-hydroxybenzoate decarboxylase) CCV52592_1585 206 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 154173843 Common - methionine import ATP-binding protein MetN CCV52592_1075 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 154174414 Common - hydrolase, carbon-nitrogen family CCV52592_0982 133 COG0388 COG0388, Predicted amidohydrolase General function prediction only 154174316 Common - putative perosamine synthetase CCV52592_1203 193 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 154174905 Common flgG flagellar basal-body rod protein FlgG CCV52592_0104 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 154175425 Common - hypothetical protein CCV52592_0555 13 None None None 154175152 Common - biopolymer transport ExbB protein CCV52592_1653 204 COG0782 GreA, Transcription elongation factor Transcription 154174850 Common - hypothetical protein CCV52592_1524 6 None None None 154173723 Common - thiol:disulfide interchange protein DsbA CCV52592_1147 29 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 154173840 Common nusB transcription antitermination factor NusB CCV52592_1180 162 COG0781 NusB, Transcription termination factor Transcription 154173768 Pathogen - hypothetical protein CCV52592_1577 1 None None None 154175234 Common tkt transketolase CCV52592_0069 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 154175338 Common yitK conserved protein YitK CCV52592_1912 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 154174612 Common - methionine import ATP-binding protein MetN CCV52592_0478 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 154174720 Common - putative transcriptional regulator CCV52592_0263 190 COG0583 LysR, Transcriptional regulator Transcription 154174857 Common - hypothetical protein CCV52592_0537 6 None None None 154175205 Common - bifunctional protein HldE CCV52592_0832 3 None None None 154175345 Common - succinate dehydrogenase and fumarate reductase iron-sulfur protein CCV52592_2206 207 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 154175499 Common rfaD ADP-glyceromanno-heptose 6-epimerase CCV52592_0243 231 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154175302 Common - hypothetical protein CCV52592_0310 13 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 154175175 Common dcd deoxycytidine triphosphate deaminase CCV52592_0559 153 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 154174106 Common - aldehyde dehydrogenase (NAD) family protein CCV52592_1278 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 154174059 Common - taurine transport system permease protein TauC CCV52592_1129 198 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 154174783 Common - homoserine dehydrogenase (HDH) CCV52592_0834 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 154174679 Pathogen - hypothetical protein CCV52592_1875 1 None None None 154174440 Common - hypothetical protein CCV52592_0258 3 None None None 154175524 Common czcD cation-efflux system membrane protein CCV52592_0201 142 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154175015 Common - putative methyltransferase CCV52592_1715 148 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 154175492 Common nusG transcription termination/antitermination factor NusG CCV52592_0176 214 COG0250 NusG, Transcription antiterminator Transcription 154175103 Common - maturase-related protein CCV52592_0302 55 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 154174621 Common - hypothetical protein CCV52592_0711 7 None None None 154174465 Common - translation initiation factor IF-2 CCV52592_0355 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 154173663 Common - type I restriction-modification system S subunit CCV52592_0371 34 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 154174016 Common truA tRNA pseudouridine synthase A CCV52592_1426 229 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 154174470 Common - succinate dehydrogenase flavoprotein subunit CCV52592_1873 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 154174925 Common - pyridoxamine 5'-phosphate oxidase family protein CCV52592_0652 15 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 154174141 Common - periplasmic nitrate reductase component NapD CCV52592_1934 7 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 154175075 Common - methyl-accepting chemotaxis protein (MCP) signaling domain CCV52592_0397 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 154173671 Common - hemin-binding periplasmic protein HmuT CCV52592_0648 158 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 154174424 Common - protein of unknown function , transmembrane CCV52592_0331 29 COG1814 COG1814, Uncharacterized membrane protein Function unknown 154175220 Common - 50S ribosomal protein L5 (BL6) CCV52592_1436 1 None None None 154175511 Common - ATP-dependent hsl protease ATP-binding subunit HslU CCV52592_0051 96 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 154174764 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase CCV52592_2005 225 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 154173833 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase CCV52592_0293 169 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 154174148 Pathogen - hypothetical protein CCV52592_0060 1 None None None 154174672 Common gltL glutamate/aspartate ABC transporter, ATP-binding protein CCV52592_0494 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 154175232 Common gntT GntT protein CCV52592_0520 77 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 154174745 Pathogen - hypothetical protein CCV52592_0043 1 None None None 154174714 Common - glycosyl transferase, group 2 family protein CCV52592_0972 112 COG4261 COG4261, Predicted acyltransferase General function prediction only 154174363 Common - hypothetical protein CCV52592_0863 4 None None None 154174839 Common flgB flagellar basal-body rod protein FlgB CCV52592_0693 71 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 154174549 Common - transporter CCV52592_0884 141 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 154174542 Pathogen - hypothetical protein CCV52592_0039 1 None None None 154175478 Common tig trigger factor CCV52592_1498 209 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 154174233 Common dapE succinyl-diaminopimelate desuccinylase CCV52592_0990 213 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 154175016 Common kdtA 3-deoxy-d-manno-octulosonic-acid transferase CCV52592_0462 219 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 154175202 Common rpsP ribosomal protein S16 CCV52592_0676 200 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 154174697 Common - lipid A export ATP-binding/permease protein MsbA CCV52592_1141 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 154174518 Common - cystathionine beta-lyase (CBL) (Beta-cystathionase)(Cysteine lyase) CCV52592_1206 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 154174010 Common thrC threonine synthase CCV52592_0130 135 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 154175357 Common - hypothetical protein CCV52592_0992 8 None None None 154175191 Pathogen - hypothetical protein CCV52592_1308 1 None None None 154175518 Common guaB inosine-5'-monophosphate dehydrogenase CCV52592_0979 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 154174355 Pathogen - hypothetical protein CCV52592_1451 1 None None None 154175065 Common - glycosyltransferase CCV52592_0882 21 COG4380 COG4380, Uncharacterized protein conserved in bacteria Function unknown 154175136 Common - trimethylamiNe-n-oxide reductase 1 (tmaoreductase 1) (trimethylamine oxidase 1) CCV52592_0114 158 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 154174506 Common cas crispr-associated protein Cas2 CCV52592_1288 24 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 154173884 Common xseA exodeoxyribonuclease VII, large subunit CCV52592_1675 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 154175445 Common - NADH-dependent butanol dehydrogenase a (bdh i) CCV52592_1018 219 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 154174667 Common - purine nucleoside phosphorylase CCV52592_1853 75 COG1683 COG1683, Uncharacterized conserved protein Function unknown 154175031 Pathogen napD periplasmic nitrate reductase component NapD CCV52592_0013 1 None None None 154174520 Common - copper homeostasis protein CutF CCV52592_1624 20 COG3015 CutF, Uncharacterized lipoprotein NlpE involved in copper resistance Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism 154174966 Pathogen pcm protein-L-isoaspartate O-methyltransferase CCV52592_2087 1 None None None 154175106 Common - methyl-accepting chemotaxis protein (MCP) signaling domain CCV52592_1409 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 154174034 Common - transcriptional regulator, TraR/DksA family CCV52592_1754 95 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 154175350 Common - integral membrane protein DUF6 CCV52592_1481 13 COG3356 COG3356, Predicted membrane protein Function unknown 154175368 Common - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase (1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase) CCV52592_0908 4 None None None 154174305 Common - putative periplasmic protein CCV52592_1742 3 COG5373 COG5373, Predicted membrane protein Function unknown 154174099 Common - proton/sodium-glutamate symport protein (Glutamate-aspartate carrierprotein) CCV52592_1033 165 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 154175289 Common - Mrr restriction system protein (EcoKMrr) CCV52592_1602 79 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154175505 Pathogen - hypothetical protein CCV52592_0386 7 None None None 154175341 Pathogen - NADPH dehydrogenase (xenobiotic reductase) CCV52592_1828 1 None None None 154173623 Common fabG 3-oxoacyl-(acyl-carrier-protein) reductase CCV52592_1043 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154173758 Common pheT phenylalanyl-tRNA synthetase, beta subunit CCV52592_0517 230 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 154174303 Common - trimethylamiNe-n-oxide reductase 2 (tmaoreductase 2) (trimethylamine oxidase 2) CCV52592_0392 150 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 154173941 Pathogen - hypothetical protein CCV52592_0044 2 None None None 154174686 Common - mechanosensitive ion channel family protein CCV52592_2117 230 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 154175390 Common - TrkA CCV52592_1327 3 None None None 154174772 Common glnA glutamine synthetase, type I CCV52592_0276 226 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 154175431 Common dnaK chaperone protein DnaK CCV52592_0148 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 154174335 Common - TrkA CCV52592_0721 74 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 154174223 Common fliP flagellar biosynthetic protein FliP CCV52592_1271 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 154174160 Common - radical SAM CCV52592_2101 26 COG2108 COG2108, Uncharacterized conserved protein related to pyruvate formate-lyase activating enzyme General function prediction only 154175376 Common - Sel1 repeat family CCV52592_2145 29 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154175264 Common - protein TonB CCV52592_1830 110 COG0759 COG0759, Uncharacterized conserved protein Function unknown 154173806 Common - hypothetical protein CCV52592_0938 1 None None None 154175053 Common ilvB acetolactate synthase, large subunit, biosynthetic type CCV52592_1428 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 154174490 Common - hypothetical protein CCV52592_1696 17 COG0433 COG0433, Predicted ATPase General function prediction only 154174893 Pathogen - hypothetical protein CCV52592_0749 1 None None None 154174962 Common - riboflavin biosynthesis protein CCV52592_1800 5 None None None 154173644 Common - hypothetical protein CCV52592_0261 7 None None None 154173948 Common putP sodium/proline symporter CCV52592_0491 183 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 154174216 Common - hypothetical protein CCV52592_2240 7 None None None 154173997 Pathogen - hypothetical protein CCV52592_1935 1 None None None 154175326 Common miaB tRNA-I(6)A37 thiotransferase enzyme MiaB CCV52592_0260 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 154174863 Common rpsK ribosomal protein S11 CCV52592_1010 247 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 154173740 Common rplV ribosomal protein L22 CCV52592_1028 213 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 154174026 Common - hypothetical protein CCV52592_0724 3 None None None 154174529 Pathogen - hypothetical protein CCV52592_1888 1 None None None 154174587 Common - rhomboid family protein CCV52592_1090 125 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 154174926 Common secF protein-export membrane protein SecF CCV52592_0708 219 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 154173853 Common - alpha/beta hydrolase fold domain protein CCV52592_0665 122 COG0657 Aes, Esterase/lipase Lipid metabolism 154173879 Common rplP ribosomal protein L16 CCV52592_1026 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 154174092 Common - chemotaxis response regulator protein-glutamate methylesterase CCV52592_1332 142 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 154173747 Common - 3-deoxy-D-manno-octulosonic-acid transferase (KDOtransferase) CCV52592_0673 125 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 154174255 Common - peptidase, M16 (pitrilysin) family CCV52592_2215 186 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 154174752 Common - ferripyoverdine receptor CCV52592_0400 102 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 154173752 Common - hypothetical protein CCV52592_0709 15 None None None 154173990 Pathogen - hypothetical protein CCV52592_2152 2 None None None 154174492 Common pckA phosphoenolpyruvate carboxykinase (ATP) CCV52592_0965 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 154175087 Common - RmuC domain protein CCV52592_2033 158 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 154174558 Common - ribonucleoside-diphosphate reductase, beta subunit CCV52592_2093 156 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 154174889 Pathogen - hypothetical protein CCV52592_1246 1 None None None 154173767 Common - type III pantothenate kinase (Pantothenic acid kinase)(PanK-III) CCV52592_0993 30 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 154175041 Pathogen - hypothetical protein CCV52592_0052 1 None None None 154174881 Common - YjeF-related protein CCV52592_1503 215 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 154175452 Pathogen - hypothetical protein CCV52592_2025 1 None None None 154174155 Common - putative integral membrane protein CCV52592_0852 2 None None None 154174473 Common - nickel transport system permease protein NikB CCV52592_1322 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 154175525 Common fbaA fructose-bisphosphate aldolase, class II CCV52592_0113 120 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 154174998 Common dnaA chromosomal replication initiator protein DnaA CCV52592_2056 214 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 154174876 Common - putative methyltransferase CCV52592_1562 51 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154175383 Common - L-seryl-tRNA(Sec) selenium transferase CCV52592_0995 7 None None None 154174343 Common - hypothetical protein CCV52592_1899 5 None None None 154175301 Common - hydrogenase nickel incorporation protein HypB CCV52592_0638 60 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 154173816 Common - hypothetical protein CCV52592_0963 8 None None None 154174825 Common - hypothetical protein CCV52592_0556 1 None None None 154174284 Common - peptide methionine sulfoxide reductase MsrA/msrB CCV52592_1839 206 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 154174084 Common - putative nicotinate (nicotinamide) nucleotide adenylyltransferase CCV52592_1250 195 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 154175254 Common rplR ribosomal protein L18 CCV52592_1017 122 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 154174126 Common - transcriptional regulator, AraC family CCV52592_0526 140 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 154173771 Common pgk phosphoglycerate kinase CCV52592_1248 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 154174200 Common fusA translation elongation factor G CCV52592_0189 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 154175257 Pathogen - succinyl-CoA synthetase beta chain (SCS-alpha)(Vegetative protein 63) (VEG63) CCV52592_0621 1 None None None 154175462 Common - hypothetical protein CCV52592_1067 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 154174918 Common - two component transcriptional regulator, winged helix family CCV52592_1144 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154174139 Common folE GTP cyclohydrolase I CCV52592_1496 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 154174454 Common - hypothetical protein CCV52592_1431 12 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 154174206 Common nuoD NADH dehydrogenase (quinone), d subunit CCV52592_1526 192 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 154175361 Common - outer membrane lipoprotein MapA CCV52592_0197 82 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 154174642 Common - peptidase M23B CCV52592_2224 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 154175420 Common - FlhB domain protein CCV52592_0719 19 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 154174577 Common - asparate kinase, monofunctional class CCV52592_1570 236 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 154173728 Pathogen - hypothetical protein CCV52592_1468 1 None None None 154174937 Common - sensor histidine kinase CCV52592_0810 177 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154174613 Common serC phosphoserine aminotransferase CCV52592_1676 114 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 154174326 Common - putative membrane-bound tetrahaem cytochrome TorC/YecK CCV52592_2045 19 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 154174649 Common - hypothetical protein CCV52592_2082 6 None None None 154174130 Pathogen - hypothetical protein CCV52592_0212 1 None None None 154174846 Common fliL flagellar basal body-associated protein FliL CCV52592_1630 37 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 154174105 Common - general L-amino acid transport ATP-binding protein AapP CCV52592_0289 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 154173735 Common - CoA-substrate-specific enzyme activase domain protein CCV52592_1797 65 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 154174957 Common - lipoprotein, nlpa family CCV52592_1879 113 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 154175217 Common - OmpA/MotB CCV52592_0286 41 COG3258 COG3258, Cytochrome c Energy production and conversion 154174433 Pathogen - hypothetical protein CCV52592_1305 1 None None None 154174286 Common - putative Cell division protease FtsH-like protein CCV52592_1068 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 154173621 Common ilvN acetolactate synthase, small subunit CCV52592_1429 190 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 154174762 Common - helicase, UvrD/Rep family CCV52592_0699 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 154173989 Common - flavodoxin CCV52592_2018 31 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 154173972 Common - single-stranded DNA-binding protein (SSB) (Helix-destabilizingprotein) CCV52592_0058 185 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 154173825 Common - hypothetical protein CCV52592_0023 7 None None None 154174980 Common - hypothetical protein CCV52592_0562 91 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 154175438 Common - acyl carrier protein CCV52592_0379 4 None None None 154175222 Common cysS cysteinyl-tRNA synthetase CCV52592_1142 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154174722 Common - DNA protection during starvation protein CCV52592_0191 124 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 154173876 Common - hypothetical protein CCV52592_0837 3 None None None 154174402 Common - aminoacyl-histidine dipeptidase CCV52592_0116 53 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 154174442 Common - putative chemotaxis protein MotB CCV52592_0111 26 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 154174017 Common lpxA acyl-[acyl-carrier-protein]-UDP-N-acetylglucosamine O-acyltransferase CCV52592_0866 149 COG1043 LpxA, Acyl- acyl carrier protein 154174150 Common - iron-sulfur cluster-binding domain protein CCV52592_0539 48 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 154175541 Common - hypothetical protein CCV52592_1115 165 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 154175164 Common murF UDP-MurNac-pentapeptide presynthetase CCV52592_1949 56 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 154175003 Common proS prolyl-tRNA synthetase CCV52592_0765 244 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154174755 Pathogen - hypothetical protein CCV52592_1601 1 None None None 154174673 Common - hypothetical protein CCV52592_0597 4 None None None 154174429 Common argG argininosuccinate synthase CCV52592_1976 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 154174848 Common sppA signal peptide peptidase SppA, 36K type CCV52592_0361 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154175459 Pathogen - glutamyl-tRNA reductase (GluTR) CCV52592_1591 1 None None None 154173709 Common secE preprotein translocase, SecE subunit CCV52592_0175 6 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 154173749 Common - putative epimerase/dehydratase WbiI CCV52592_1202 182 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154175219 Pathogen - transformation system protein CCV52592_2132 1 None None None 154174446 Common uvrA excinuclease ABC, A subunit CCV52592_1703 234 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 154174422 Common - bifunctional protein FolD CCV52592_0799 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 154174371 Common - molybdenum import ATP-binding protein ModC CCV52592_0583 4 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 154175403 Common cheR CheR methyltransferase, SAM binding domain protein CCV52592_1333 150 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 154174760 Pathogen - hypothetical protein CCV52592_0034 1 None None None 154173788 Common - probable inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase) CCV52592_0464 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 154173737 Common - hypothetical protein CCV52592_1102 7 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 154174903 Common - acyltransferase CCV52592_1229 116 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 154173862 Common - hypothetical protein CCV52592_0636 8 None None None 154174353 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase CCV52592_1101 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 154174994 Pathogen - hypothetical protein CCV52592_0826 1 None None None 154174865 Common - YceI CCV52592_1334 119 COG2353 COG2353, Uncharacterized conserved protein Function unknown 154174481 Common - hypothetical protein CCV52592_1578 22 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 154173685 Common - OorB subunit of 2-oxoglutarate:acceptor oxidoreductase CCV52592_1878 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 154175134 Common - hypothetical protein CCV52592_1474 44 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 154174684 Common - electron transport protein HydN CCV52592_1792 149 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 154174274 Common - hypothetical protein CCV52592_0723 2 None None None 154174247 Pathogen - hypothetical protein CCV52592_0017 1 None None None 154174913 Common - outer membrane receptor for fe CCV52592_1999 90 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 154174858 Common - twitching mobility protein CCV52592_1661 220 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 154175410 Common - peptidase T CCV52592_2106 162 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 154174341 Common - putative oligoendopeptidase F CCV52592_0701 87 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 154174553 Pathogen - hypothetical protein CCV52592_0825 1 None None None 154174602 Common - hypothetical protein CCV52592_1003 7 None None None 154175245 Common - hypothetical protein CCV52592_1134 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 154175292 Common - yggt family protein CCV52592_1233 82 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 154174734 Common - hypothetical protein CCV52592_0158 4 None None None 154174590 Pathogen - hypothetical protein CCV52592_1063 1 None None None 154174295 Common - purine nucleoside phosphorylase CCV52592_1118 7 None None None 154175538 Common proA gamma-glutamyl phosphate reductase CCV52592_0754 201 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 154175210 Common - CoA-binding domain protein CCV52592_0247 84 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154175200 Common - abc transporter, ATP-binding protein CCV52592_0219 122 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 154174337 Common - NADH-quinone oxidoreductase chain l (NADH dehydrogenase i, chain l) (ndh-1, chain l) CCV52592_1518 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 154175312 Pathogen - DedA family protein CCV52592_2175 1 None None None 154175209 Common - putative ABC transporter, ATP-binding protein CCV52592_1128 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 154175381 Common gltX glutamyl-tRNA synthetase CCV52592_0548 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 154173984 Common ansB L-asparaginase II CCV52592_1362 132 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 154173845 Common - hypothetical protein CCV52592_2216 4 None None None 154175307 Common fliM flagellar motor switch protein FliM CCV52592_1439 106 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 154175064 Common modA molybdate ABC transporter, periplasmic molybdate-binding protein CCV52592_0584 149 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 154174112 Pathogen - hypothetical protein CCV52592_1380 1 None None None 154175114 Pathogen - hypothetical protein CCV52592_2118 1 None None None 154174104 Common - hypothetical protein CCV52592_0536 2 None None None 154175317 Common - PP-loop family CCV52592_0255 200 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 154174062 Common - hypothetical protein CCV52592_0672 52 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 154174817 Common - integral membrane protein CCV52592_1400 71 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 154175177 Common - CbiM CCV52592_0557 23 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 154174795 Common - hypothetical protein CCV52592_0761 5 None None None 154173631 Common napB periplasmic nitrate reductase, diheme cytochrome c subunit CCV52592_1931 37 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 154173832 Common - anaerobic ribonucleoside-triphosphate reductase activating protein CCV52592_1126 79 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 154174188 Common - flagellin CCV52592_0107 80 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 154175272 Common - ubiquinol--cytochrome c reductase, cytochrome c1 subunit CCV52592_0554 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 154174692 Common - 4-carboxymuconolactone decarboxylase CCV52592_2032 47 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 154174792 Common - hypothetical protein CCV52592_0455 4 None None None 154175047 Common rplI ribosomal protein L9 CCV52592_1975 215 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 154174318 Common - sodium/hydrogen exchanger family protein CCV52592_1861 211 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 154174999 Common - N-acetylmuramoyl-L-alanine amidase domain protein CCV52592_0486 179 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 154175495 Common rplS ribosomal protein L19 CCV52592_0680 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 154174804 Common tatC twin arginine-targeting protein translocase TatC CCV52592_1575 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 154175024 Pathogen trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase CCV52592_0211 1 None None None 154175008 Common - hypothetical protein CCV52592_1695 169 COG0344 COG0344, Predicted membrane protein Function unknown 154175126 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA CCV52592_1793 193 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 154174811 Common - hypothetical protein CCV52592_1644 1 None None None 154173665 Common - WabG CCV52592_1236 146 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154175155 Common - trigger factor (TF) (Vegetative protein 2) (VEG2) CCV52592_1342 182 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 154175465 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase CCV52592_1324 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 154174197 Common clpX ATP-dependent Clp protease, ATP-binding subunit ClpX CCV52592_0867 221 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 154175544 Common - Xaa-Pro dipeptidase CCV52592_1794 129 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 154174070 Common - D-methionine transport system permease protein MetI CCV52592_1074 111 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 154174055 Common - RRF2 family protein CCV52592_1447 63 COG1959 COG1959, Predicted transcriptional regulator Transcription 154173966 Common ilvA threonine dehydratase CCV52592_1422 205 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 154175352 Pathogen - ribosomal protein S4 CCV52592_1157 2 None None None 154174328 Common proB glutamate 5-kinase CCV52592_0755 200 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 154174891 Common rplT ribosomal protein L20 CCV52592_0347 215 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 154174631 Common - glutamyl-Q tRNA(Asp) synthetase (Glu-Q-RSs) CCV52592_0507 238 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 154174504 Common - hypothetical protein CCV52592_1275 2 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154174977 Common - methyltransferase CCV52592_2218 246 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 154174726 Common - hypothetical protein CCV52592_1550 1 None None None 154175078 Common - putative highly acidic protein CCV52592_0075 62 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154174655 Common hisG ATP phosphoribosyltransferase CCV52592_0991 200 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 154174165 Common - fibronectin/fibrinogen-binding protein CCV52592_0598 60 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 154174321 Common - excinuclease ATPase subunit CCV52592_1161 15 None None None 154175199 Common - anthranilate synthase component II CCV52592_1709 116 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 154174820 Common - hypothetical protein CCV52592_1272 16 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154173808 Pathogen - hypothetical protein CCV52592_2214 1 None None None 154173854 Common - hypothetical protein CCV52592_1848 6 None None None 154174615 Common - hypothetical protein CCV52592_1382 3 None None None 154174119 Common - ribonuclease BN CCV52592_0327 99 COG1295 Rbn, Predicted membrane protein Function unknown 154173927 Common gmk guanylate kinase CCV52592_1256 213 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 154173901 Pathogen - hypothetical protein CCV52592_1646 1 None None None 154173954 Common - penicillin-binding protein 1A (PBP-1a) (PBP1a) CCV52592_0683 206 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 154173691 Pathogen - hypothetical protein CCV52592_1606 1 None None None 154174647 Common - abcb protein CCV52592_0423 155 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 154175115 Common - general stress protein 14 (GSP14) CCV52592_1166 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154173794 Common - hypothetical protein CCV52592_1366 4 None None None 154175148 Common htrA serine protease CCV52592_2156 10 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154175050 Common - dTDP-glucose 4,6-dehydratase CCV52592_1323 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 154175488 Pathogen - PP-loop family protein CCV52592_1785 1 None None None 154173795 Common - hypothetical protein CCV52592_0785 5 None None None 154174004 Common - autotransporter CCV52592_0420 2 None None None 154175098 Common trmA tRNA (uracil-5-)-methyltransferase CCV52592_1420 171 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 154175282 Common ylxH ATP-binding protein CCV52592_1791 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 154173766 Pathogen - hypothetical protein CCV52592_1340 1 None None None 154174406 Common - hypothetical protein CCV52592_0909 22 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 154174175 Pathogen - hypothetical protein CCV52592_2226 1 None None None 154175013 Common plsX fatty acid/phospholipid synthesis protein PlsX CCV52592_1700 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 154174530 Common - N-carbamoyl-L-amino acid hydrolase (L-carbamoylase) CCV52592_2070 89 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 154174710 Common - hydrogenase-4 component C CCV52592_1790 91 COG0650 HyfC, Formate hydrogenlyase subunit 4 Energy production and conversion 154175473 Pathogen - flavodoxin family protein CCV52592_0490 1 None None None 154173921 Common trmE tRNA modification GTPase TrmE CCV52592_1833 225 COG0486 ThdF, Predicted GTPase General function prediction only 154173702 Common - TonB-dependent receptor domain protein CCV52592_0425 39 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154174228 Common - peptidyl-arginine deiminase family protein CCV52592_0085 88 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 154174032 Common hemL glutamate-1-semialdehyde-2,1-aminomutase CCV52592_0797 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 154174890 Common - AlgI CCV52592_0864 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 154174579 Common - hypothetical protein CCV52592_0850 2 None None None 154174307 Common - ribonuclease P protein component CCV52592_1829 2 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 154174489 Common - flavocytochrome c flavin subunit CCV52592_1548 66 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 154175287 Pathogen - YbaK CCV52592_1994 3 None None None 154175397 Pathogen - putative lipoprotein CCV52592_0804 1 None None None 154174221 Common - sugar transferase CCV52592_1235 208 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 154174497 Common pgpA phosphatidylglycerophosphatase A CCV52592_0199 97 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 154174152 Common ribH 6,7-dimethyl-8-ribityllumazine synthase CCV52592_1181 230 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 154174143 Common purD phosphoribosylamine--glycine ligase CCV52592_0949 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 154175366 Pathogen - hypothetical protein CCV52592_1561 2 None None None 154175138 Common gppA guanosine pentaphosphate phosphohydrolase CCV52592_1702 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 154175033 Common - hypothetical protein CCV52592_2041 22 COG4679 COG4679, Phage-related protein Function unknown 154174968 Common - putative type II/IV secretion system protein CCV52592_0998 213 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 154174499 Common - transcriptional regulatory protein BaeR CCV52592_1360 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154174333 Common leuS leucyl-tRNA synthetase CCV52592_0710 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154174770 Common - hypothetical protein CCV52592_2062 5 None None None 154175486 Common - aspartate racemase CCV52592_1423 4 None None None 154173943 Common - putative cytochrome C-type haem-binding periplasmic protein CCV52592_0390 25 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 154173646 Common - hypothetical protein CCV52592_1266 3 None None None 154174948 Common ksgA dimethyladenosine transferase CCV52592_1116 246 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 154174008 Common - bifunctional protein HldE CCV52592_0244 175 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 154175262 Pathogen - thiol:disulfide interchange protein DsbD (Protein-disulfide reductase) (Disulfide reductase) CCV52592_1494 1 None None None 154175085 Common - S-adenosylmethionine synthetase CCV52592_1319 15 COG3477 COG3477, Predicted periplasmic/secreted protein Function unknown 154174964 Common - oxidoreductase, aldo/keto reductase family CCV52592_2028 124 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 154174526 Pathogen - hypothetical protein CCV52592_1277 1 None None None 154175378 Common csh crispr-associated protein, Csh2 family CCV52592_1292 54 COG3649 COG3649, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 154174570 Common ffh signal recognition particle protein CCV52592_0675 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 154174418 Common - hypothetical protein CCV52592_2034 3 None None None 154174527 Common - putative diguanylate cyclase/phosphodiesterase CCV52592_1484 168 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 154173835 Common pyrB aspartate carbamoyltransferase CCV52592_0155 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 154173730 Common - histidine biosynthesis bifunctional protein hisIE CCV52592_0853 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 154174779 Common - hypothetical protein CCV52592_0632 2 None None None 154174411 Common - spore coat polysaccharide biosynthesis protein SpsC CCV52592_0561 191 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 154174511 Common - D-methionine-binding lipoprotein MetQ CCV52592_1073 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 154174263 Common thiE thiamine-phosphate pyrophosphorylase CCV52592_0497 193 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 154175404 Common - NAD dependent epimerase/dehydratase family CCV52592_2017 103 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 154174929 Common - P-protein CCV52592_1666 215 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 154174540 Common ccoO cytochrome c oxidase, Cbb3-type, subunit II CCV52592_0903 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 154174451 Common - TonB dependent receptor CCV52592_1080 70 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 154173743 Common - prokaryotic N- methylation motif domain protein CCV52592_0100 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 154174537 Common - hypothetical protein CCV52592_0449 176 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 154175333 Common - ferredoxin-type protein, NapH/MauN family CCV52592_0668 73 COG0348 NapH, Polyferredoxin Energy production and conversion 154174785 Common - ubiquinone/menaquinone biosynthesis methyltransferase UbiE CCV52592_1674 198 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154174547 Common - putative integral membrane protein CCV52592_1823 6 None None None 154174348 Common - hypothetical protein CCV52592_1309 4 None None None 154173821 Pathogen - hypothetical protein CCV52592_1621 1 None None None 154174670 Pathogen - nodulation efficiency protein D (NfeD) CCV52592_1623 1 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154174566 Common - hydrogenase maturation protease superfamily CCV52592_1639 23 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 154175447 Common glyA serine hydroxymethyltransferase CCV52592_1350 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 154175516 Common - putative ftsk/spoiiie family CCV52592_1296 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 154174438 Common - feruloyl-CoA synthetase CCV52592_1489 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154175415 Common - ribosomal protein L7/L12 CCV52592_1529 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 154174916 Pathogen - hypothetical protein CCV52592_1913 1 None None None 154175215 Common - CmeB CCV52592_0413 80 COG1279 COG1279, Lysine efflux permease General function prediction only 154174202 Common - putative endonuclease/exonuclease/phosphatase CCV52592_1372 8 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 154173882 Common - hypothetical protein CCV52592_0015 10 None None None 154175252 Common - transporter, monovalent cation:proton antiporter-2 (CPA2) family CCV52592_0575 38 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 154174759 Common - glycerol-3-phosphate dehydrogenase (NAD(P)+) CCV52592_0792 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 154174727 Common - antibiotic biosynthesis monooxygenase domain protein CCV52592_2210 3 COG1359 COG1359, Uncharacterized conserved protein Function unknown 154174467 Pathogen - hypothetical protein CCV52592_1600 1 None None None 154175280 Pathogen - cystathionine beta-lyase (CBL) (Beta-cystathionase)(Cysteine lyase) (Osteotoxin) CCV52592_0807 1 None None None 154174086 Common - putative chorismate binding enzyme CCV52592_1310 13 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 154173982 Common - prophage LambdaSa04, RelE/ParE family protein CCV52592_0926 6 COG3668 ParE, Plasmid stabilization system protein General function prediction only 154174427 Common purL phosphoribosylformylglycinamidine synthase II CCV52592_1835 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 154174357 Pathogen - hypothetical protein CCV52592_0821 1 None None None 154175455 Common - nucleotide sugar dehydrogenase subfamily CCV52592_1221 207 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 154175001 Common - putative ABC transporter, permease protein CCV52592_1759 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 154174350 Common - transcription Regulator Protein CCV52592_1551 96 COG1309 AcrR, Transcriptional regulator Transcription 154174025 Common - putative helix-turn-helix containsing protein CCV52592_1064 10 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 154175193 Common - dimethyladenosine transferase CCV52592_1990 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 154175329 Common - hypothetical protein CCV52592_1425 1 None None None 154174743 Common dctA C4-dicarboxylate transport protein CCV52592_1035 157 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 154174636 Common - C4-dicarboxylate transport system permease, large subunit CCV52592_2121 135 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 154174669 Common - membrane fusion protein of the hefABC efflux system HefB CCV52592_1273 118 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154174098 Common - Xaa-Pro peptidase CCV52592_0365 180 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 154174869 Common - NADH-dependent butanol dehydrogenase a (bdh i) CCV52592_2016 172 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 154174132 Common - ABC-transporter ATP-binding protein CCV52592_1982 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 154174391 Pathogen - hypothetical protein CCV52592_2079 1 None None None 154173706 Common - peptidase E CCV52592_2072 27 COG3340 PepE, Peptidase E Amino acid transport and metabolism 154174935 Common - hypothetical protein CCV52592_1966 5 None None None 154174660 Common - spfh domain / band 7 family protein CCV52592_1616 96 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 154173995 Common cysE serine O-acetyltransferase CCV52592_0718 218 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 154174640 Common - NAD(p)-specific glutamate dehydrogenase CCV52592_0886 165 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 154173865 Common - prophage Lp2 protein 3 CCV52592_0050 36 COG0338 Dam, Site-specific DNA methylase DNA replication, recombination, and repair 154173858 Common - hypothetical protein CCV52592_1950 10 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 154174742 Common ccoN cytochrome c oxidase, Cbb3-type, subunit I CCV52592_0902 134 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 154173851 Common - putative heat shock protein HspR CCV52592_1862 98 COG0789 SoxR, Predicted transcriptional regulators Transcription 154173814 Common - NADH dehydrogenase subunit c CCV52592_1527 170 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 154174860 Common - hypothetical protein CCV52592_0681 13 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 154173734 Pathogen rusA crossover junction endodeoxyribonuclease RusA superfamily CCV52592_0040 1 None None None 154173742 Common upp uracil phosphoribosyltransferase CCV52592_0546 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 154174074 Common - beta-lactamase HcpA (Cysteine-rich 28 kDaprotein) CCV52592_0080 57 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154175019 Pathogen - N- methylation CCV52592_0906 1 None None None 154174181 Pathogen - hypothetical protein CCV52592_0053 1 None None None 154174209 Common - methionine import ATP-binding protein MetN CCV52592_1434 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 154174873 Common - ABC transporter ATP-binding protein YojI CCV52592_1530 249 COG4615 PvdE, ABC-type siderophore export system, fused ATPase and permease components Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 154174257 Common - flavocytochrome c flavin subunit CCV52592_0003 67 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 154175142 Common - 30S ribosomal protein S12 CCV52592_1537 10 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 154174227 Common - putative lipoprotein CCV52592_1460 11 COG3018 COG3018, Uncharacterized protein conserved in bacteria Function unknown 154175243 Pathogen - sulfate/thiosulfate import ATP-binding protein CysA (Sulfate-transporting ATPase) CCV52592_1357 1 None None None 154174928 Common selB selenocysteine-specific translation elongation factor CCV52592_0541 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 154174163 Common ung uracil-DNA glycosylase CCV52592_1111 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 154174841 Common apt adenine phosphoribosyltransferase CCV52592_1315 173 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 154175339 Common - hypothetical protein CCV52592_1816 12 COG2857 CYT1, Cytochrome c1 Energy production and conversion 154175343 Common - molydopterin dinucleotide binding domain protein CCV52592_0534 181 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 154173633 Common uvrC excinuclease ABC, C subunit CCV52592_0936 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 154174242 Common nspC carboxynorspermidine decarboxylase CCV52592_0396 60 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 154173754 Common rnc ribonuclease III CCV52592_2065 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 154173628 Common - hypothetical protein CCV52592_0802 13 None None None 154175429 Pathogen - 4'-phosphopantetheinyl transferase superfamily CCV52592_1169 2 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 154174887 Common - GTP pyrophosphokinase (ATP:GTP 3'-pyrophosphotransferase)(ppGpp synthetase I) ((P)ppGpp synthetase) CCV52592_0483 208 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 154173658 Common - branched chain amino acid transport protein AzlD CCV52592_0101 12 COG1687 AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) Amino acid transport and metabolism 154175303 Common - acetyltransferase, gnat family CCV52592_0564 8 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 154174041 Common - NLP/P60 CCV52592_1855 31 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 154174456 Common trpC indole-3-glycerol phosphate synthase CCV52592_1952 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 154175523 Pathogen - arylsulfotransferase CCV52592_0118 1 None None None 154174116 Common dapB dihydrodipicolinate reductase CCV52592_0841 215 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 154174240 Common - MMT1 protein CCV52592_0272 192 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 154174695 Common - GMP synthase [glutamine-hydrolyzing] (Glutamineamidotransferase) (GMP synthetase) CCV52592_0940 241 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 154174293 Common - hypothetical protein CCV52592_1719 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 154175503 Common - site-specific recombinase, phage integrase family CCV52592_1635 191 COG3261 HycE, Ni,Fe-hydrogenase III large subunit Energy production and conversion 154174682 Pathogen - hypothetical protein CCV52592_0328 1 None None None 154174592 Common galE UDP-glucose 4-epimerase CCV52592_1224 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 154174249 Common rpsQ ribosomal protein S17 CCV52592_1024 214 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 154174736 Common - peptidase M50 CCV52592_0801 78 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 154174833 Common rplN ribosomal protein L14 CCV52592_1023 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 154174298 Common rnhB ribonuclease HII CCV52592_1765 233 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 154174992 Common - hypothetical protein CCV52592_1150 5 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 154175299 Pathogen - hypothetical protein CCV52592_2140 1 None None None 154175052 Common - metallo-beta-lactamase family protein CCV52592_0092 12 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 154175100 Pathogen - excinuclease ATPase subunit CCV52592_2168 1 None None None 154175290 Common flgC flagellar basal-body rod protein FlgC CCV52592_0692 123 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 154173700 Common - phosphate acetyltransferase (Phosphotransacetylase) CCV52592_1159 160 COG0280 Pta, Phosphotransacetylase Energy production and conversion 154174210 Common flgH flagellar L-ring protein FlgH CCV52592_1427 97 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 154175309 Common - tRNA synthetase class II core domain (G, H, P, S and T) protein CCV52592_1783 67 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 154175128 Common - ComEA protein CCV52592_0452 74 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 154173894 Common - hypothetical protein CCV52592_0369 4 None None None 154175412 Common - FO synthase subunit 2 2 (7,8-didemethyl-8-hydroxy-5-deazariboflavin synthase subunit 2 2) CCV52592_0823 124 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 154173847 Common gmhA phosphoheptose isomerase CCV52592_0245 125 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 154173683 Common - RNA polymerase sigma factor RpoD (Sigma-A) (Major vegetative sigmafactor) CCV52592_0106 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 154173823 Common glyS glycyl-tRNA synthetase, beta subunit CCV52592_1374 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 154174239 Common - transcriptional regulator, MerR family protein CCV52592_0889 9 COG0789 SoxR, Predicted transcriptional regulators Transcription 154174729 Common - undecaprenyl-phosphate galactosephosphotransferase CCV52592_0291 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 154174901 Common - putative cytoplasmic chaperone TorD subfamily CCV52592_2104 30 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 154175109 Common ppi peptidyl-prolyl cis-trans isomerase CCV52592_1078 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 154174385 Common - alkaline phosphatase synthesis transcriptional regulatory proteinphoP CCV52592_0808 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154174067 Common - hypothetical protein CCV52592_1887 10 None None None 154173923 Pathogen - hypothetical protein CCV52592_1609 1 None None None 154174404 Common - prenyl transferase CCV52592_0763 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 154175521 Common - dual specificity phosphatase, catalytic domain protein CCV52592_1172 21 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 154174408 Common - ncair mutase CCV52592_1717 64 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 154174852 Common - sec-independent translocase CCV52592_1574 11 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 154173718 Common - acid membrane antigen A CCV52592_1921 114 COG0628 PerM, Predicted permease General function prediction only 154174289 Pathogen - hypothetical protein CCV52592_0784 1 None None None 154175475 Pathogen - TonB-dependent siderophore receptor CCV52592_0524 1 None None None 154174019 Common mrdA penicillin-binding protein 2 CCV52592_0450 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 154174046 Common - formate dehydrogenase iron-sulfur subunit CCV52592_0533 164 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 154174444 Common trpS tryptophanyl-tRNA synthetase CCV52592_1188 240 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154173970 Common - phospholipase A CCV52592_0610 52 COG2829 PldA, Outer membrane phospholipase A Cell envelope biogenesis, outer membrane 154173934 Common - sodium-dependent transporter CCV52592_1763 77 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 154174543 Common uvrB excinuclease ABC, B subunit CCV52592_0317 230 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 154175224 Common - transcriptional regulator, AraC family CCV52592_2081 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 154174708 Common - hypothetical protein CCV52592_0820 4 None None None 154175060 Common asd aspartate-semialdehyde dehydrogenase CCV52592_1463 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 154175388 Common - thioredoxin reductase (trxr) (general stress protein 35)(Gsp35) CCV52592_0124 195 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 154174996 Common - UvrABC system protein A (UvrA protein) (Excinuclease ABC subunit A) CCV52592_1690 4 None None None 154174717 Common - putative uracil-DNA glycosylase superfamily CCV52592_1827 141 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 154174448 Pathogen - hypothetical protein CCV52592_1714 1 None None None 154174157 Pathogen - hypothetical protein CCV52592_1341 1 None None None 154174645 Common - geranyltranstransferase (Farnesyl-diphosphate synthase)(FPP synthase) CCV52592_0071 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 154174380 Common - hypothetical TonB dependent receptor CCV52592_1610 93 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154174312 Common - hypothetical protein CCV52592_1508 7 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 154174420 Common - motility accessory factor CCV52592_0566 20 COG2604 COG2604, Uncharacterized protein conserved in bacteria Function unknown 154175536 Pathogen - hypothetical protein CCV52592_0210 1 None None None 154173956 Common - macrolide export ATP-binding/permease protein MacB CCV52592_0428 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 154174626 Pathogen - hypothetical protein CCV52592_0381 1 None None None 154173759 Common - exbd\tolr family transport protein CCV52592_1741 132 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 154174675 Common - threonine synthase CCV52592_0269 210 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 154175166 Common glnQ glutamine ABC transporter, ATP-binding protein CCV52592_0876 47 COG0640 ArsR, Predicted transcriptional regulators Transcription 154175249 Common - hypothetical protein CCV52592_0424 27 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 154174276 Common - acyl carrier protein CCV52592_0969 40 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154174911 Common - putative type I restriction-modification system, S subunit CCV52592_1061 77 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 154173828 Pathogen - hypothetical protein CCV52592_0630 2 COG4092 COG4092, Predicted glycosyltransferase involved in capsule biosynthesis Cell envelope biogenesis, outer membrane 154174109 Common - hypothetical protein CCV52592_0403 15 None None None 154173864 Common ribE riboflavin synthase, alpha subunit CCV52592_1908 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 154175196 Common - chemotaxis protein methyltransferase CCV52592_0716 87 COG2231 COG2231, Uncharacterized protein related to Endonuclease III DNA replication, recombination, and repair 154173980 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase CCV52592_2001 158 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 154174002 Common ftsH cell division protein FtsH CCV52592_1196 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 154174075 Common - transcription regulator CCV52592_0436 150 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 154173667 Common - amino acid ABC transporter, permease protein, His/Glu/Gln/Arg/opine family CCV52592_0288 164 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 154175483 Common - sigma 54 modulation protein/ribosomal protein S30EA CCV52592_1453 34 COG2014 COG2014, Uncharacterized conserved protein Function unknown 154173907 Common rpsM ribosomal protein S13p/S18e CCV52592_1011 230 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 154175467 Pathogen - hypothetical protein CCV52592_0135 1 None None None 154174532 Pathogen - hypothetical protein CCV52592_0194 1 None None None 154173803 Common - putative methyltransferase CCV52592_0781 131 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 154174190 Common - dead/deah box helicase:hd domain CCV52592_1290 85 COG1203 COG1203, Predicted helicases General function prediction only 154174617 Common rrmJ ribosomal RNA large subunit methyltransferase J CCV52592_1564 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 154173648 Common - YitW CCV52592_1842 142 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 154174235 Common - mate efflux family protein CCV52592_0875 163 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 154175310 Common hypD hydrogenase expression/formation protein HypD CCV52592_1891 108 COG0409 HypD, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 154174555 Common ruvA holliday junction DNA helicase RuvA CCV52592_1151 208 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 154174788 Common - putative flagellar protein CCV52592_0563 25 COG3980 spsG, Spore coat polysaccharide biosynthesis protein, predicted glycosyltransferase Cell envelope biogenesis, outer membrane 154174952 Common - acetyltransferase, gnat family CCV52592_1220 8 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 154173781 Common - hypothetical protein CCV52592_2202 132 COG1739 COG1739, Uncharacterized conserved protein Function unknown 154173918 Common rpmA ribosomal protein L27 CCV52592_1725 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 154175437 Pathogen - carbamoyltransferase HypF CCV52592_0643 1 None None None 154174716 Common - glycosyltransferase CCV52592_0296 52 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154174753 Common - putative RhtB protein CCV52592_1071 110 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 154173797 Common - dgqhr domain protein CCV52592_0942 4 None None None 154174986 Common - ferric receptor CfrA CCV52592_0549 67 None None None 154174657 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase CCV52592_1045 228 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 154175095 Common topA DNA topoisomerase I CCV52592_0571 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 154175055 Common - hamp domain protein CCV52592_1359 145 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154174144 Common - HIT family protein CCV52592_1920 55 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 154174975 Pathogen - bifunctional protein FolD CCV52592_2154 1 None None None 154174712 Common - VanZ family protein CCV52592_1394 9 None None None 154174638 Common coaD pantetheine-phosphate adenylyltransferase CCV52592_1097 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 154175274 Common - acetohydroxy acid synthase large subunit CCV52592_0230 86 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 154174390 Common - methionine gamma-lyase (L-methioninase) CCV52592_1762 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 154175315 Common atpH ATP synthase F1, delta subunit CCV52592_1735 25 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 154173874 Common - polysaccharide biosynthesis protein CCV52592_1219 15 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 154174064 Common - UDP-glucose 6-dehydrogenase CCV52592_1223 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 154174487 Common - permease YjgP/YjgQ CCV52592_1263 14 COG0795 COG0795, Predicted permeases General function prediction only 154175069 Common - aldehyde dehydrogenase CCV52592_0294 150 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154175045 Pathogen - peptide chain release factor 2 (RF-2) CCV52592_0839 1 None None None 154174701 Common - peptidase, M16 family CCV52592_1139 188 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 154174524 Common - hypothetical protein CCV52592_1407 86 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 154175120 Pathogen - NADPH-dependent 7-cyano-7-deazaguanine reductase (nadph-dependent nitrile oxidoreductase) CCV52592_1000 1 None None None 154174475 Common - outer-membrane lipoprotein carrier protein CCV52592_1858 7 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 154174802 Common - hypothetical protein CCV52592_1981 155 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 154174501 Common - transcriptional regulator, ArsR family CCV52592_2058 26 COG0640 ArsR, Predicted transcriptional regulators Transcription 154174361 Common - hypothetical protein CCV52592_0217 11 None None None 154174690 Common - arylsulfotransferase CCV52592_0844 9 None None None 154175062 Common yvfE pyridoxal phosphate-dependent enzyme CCV52592_2170 2 None None None 154174539 Common - multidrug-efflux transporter CCV52592_0410 229 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154174793 Common - hypothetical protein CCV52592_1965 2 None None None 154175035 Pathogen ubiA 4-hydroxybenzoate octaprenyltransferase CCV52592_0144 1 None None None 154174826 Pathogen - hypothetical protein CCV52592_0103 1 None None None 154174110 Common - putative TonB dependent receptor CCV52592_2212 26 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154174790 Common - putative diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor CCV52592_1782 182 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 154174265 Common - tripartite ATP-independent periplasmic transporter, DctQ component CCV52592_0961 77 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 154174195 Common - DNA polymerase III, delta subunit superfamily CCV52592_1584 7 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 154173678 Common - putative permease CCV52592_0086 4 None None None 154175240 Pathogen - twin-arginine translocation protein TatA/E CCV52592_1817 1 None None None 154175157 Common accA acetyl-CoA carboxylase, carboxyl transferase, alpha subunit CCV52592_1910 177 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 154173777 Common - hypothetical TonB dependent receptor CCV52592_1560 86 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154173707 Common - biotin sulfoxide reductase (BDS reductase) (BSOreductase) CCV52592_0394 171 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 154175108 Pathogen - hypothetical protein CCV52592_1834 2 None None None 154174583 Pathogen - putative methyl-accepting chemotaxis sensory transducer CCV52592_0046 1 None None None 154175304 Common - polysulphide reductase, NrfD superfamily CCV52592_1916 39 COG3301 NrfD, Formate-dependent nitrite reductase, membrane component Inorganic ion transport and metabolism 154173900 Common - hypothetical protein CCV52592_0383 7 None None None 154173968 Common - hypothetical protein CCV52592_1089 46 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 154175121 Common - hypothetical protein CCV52592_1552 8 COG2404 COG2404, Predicted phosphohydrolase (DHH superfamily) General function prediction only 154174096 Pathogen - hypothetical protein CCV52592_1514 1 None None None 154173636 Pathogen - hypothetical protein CCV52592_0188 1 None None None 154174400 Common - phosphatidylinositol glycan-class A CCV52592_0295 198 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154173682 Common - hypothetical protein CCV52592_0827 20 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 154173619 Common glmM phosphoglucosamine mutase CCV52592_0742 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 154174533 Common - lipoprotein CCV52592_0881 13 COG4259 COG4259, Uncharacterized protein conserved in bacteria Function unknown 154175547 Common gpmI 2,3-bisphosphoglycerate-independent phosphoglycerate mutase CCV52592_1044 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 154173904 Pathogen - hypothetical protein CCV52592_1464 1 None None None 154175172 Pathogen - Cys/Met metabolism pyridoxal-phosphate-dependent enzyme CCV52592_1379 1 None None None 154173676 Common - citrate transporter superfamily CCV52592_1707 2 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 154174169 Common - putative cryptic C4-dicarboxylate transporter DcuD CCV52592_1207 24 COG3069 DcuC, C4-dicarboxylate transporter Energy production and conversion 154175266 Common efp translation elongation factor P CCV52592_0511 220 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 154174189 Common coaBC phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase CCV52592_1267 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 154173698 Common - GTP-binding protein CCV52592_0453 174 COG0218 COG0218, Predicted GTPase General function prediction only 154173849 Common - flagellar motor protein CCV52592_1192 71 COG1291 MotA, Flagellar motor component Cell motility and secretion 154173713 Common - putative periplasmic protein CCV52592_1933 15 COG2319 COG2319, FOG: WD40 repeat General function prediction only 154174261 Common - hypothetical protein CCV52592_0885 7 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 154175313 Common tgt queuine tRNA-ribosyltransferase CCV52592_1432 230 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 154173925 Common - hypothetical protein CCV52592_0352 8 None None None 154173962 Common - dna-3-methyladenine glycosylase 1 CCV52592_0983 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 154175058 Common - C4-dicarboxylate transporter family protein, DctQ subunit CCV52592_1303 4 None None None 154174564 Common ybbB tRNA 2-selenouridine synthase CCV52592_1955 65 COG2603 COG2603, Predicted ATPase General function prediction only 154174486 Common rpsT ribosomal protein S20 CCV52592_0741 171 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 154173762 Common - Na+/H+ antiporter family CCV52592_1419 52 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 154175117 Common fadD long-chain-fatty-acid--CoA ligase CCV52592_0160 116 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154174582 Common - thiredoxin CCV52592_1396 73 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 154173703 Pathogen - hypothetical protein CCV52592_2164 1 None None None 154175213 Common - radical SAM domain protein CCV52592_0139 213 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 154174436 Common - putative glycosyltransferase involved in LPS biosynthesis CCV52592_1218 10 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 154173919 Common - hypothetical protein CCV52592_0266 6 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 154174115 Common ttg2D toluene tolerance protein Ttg2D CCV52592_0587 51 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 154173801 Common - 7-alpha-hydroxysteroid dehydrogenase CCV52592_1137 234 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154173798 Common rpmB ribosomal protein L28 CCV52592_0722 166 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 154174184 Common ispE 4-diphosphocytidyl-2C-methyl-D-erythritol kinase CCV52592_0696 122 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 154173958 Common - hypothetical protein CCV52592_1985 1 None None None 154174001 Common fliI flagellar protein export ATPase FliI CCV52592_1495 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 154174601 Common rpsN ribosomal protein S14p/S29e CCV52592_1020 178 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 154174023 Pathogen - hypothetical protein CCV52592_1728 1 None None None 154173799 Common - putative mannonate dehydratase CCV52592_0887 10 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 154175295 Common - type II secretion system protein CCV52592_0042 27 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 154174469 Common - putative methyltransferase CCV52592_1678 32 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 154173687 Pathogen - RNA polymerase subunit B CCV52592_0927 1 None None None 154174651 Pathogen - hypothetical protein CCV52592_0108 1 None None None 154174079 Common - hypothetical protein CCV52592_0996 6 None None None 154173850 Pathogen - hypothetical protein CCV52592_0492 1 None None None 154174347 Common rfaC lipopolysaccharide heptosyltransferase I CCV52592_1228 76 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 154173905 Common - periplasmic solute binding protein family CCV52592_0094 174 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 154174696 Pathogen - hypothetical protein CCV52592_2222 1 None None None 154175277 Common rpoZ DNA-directed RNA polymerase, omega subunit CCV52592_0482 8 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 154174382 Pathogen - hypothetical protein CCV52592_0406 1 None None None 154175022 Common - hypothetical protein CCV52592_0684 175 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 154175181 Common rplX ribosomal protein L24 CCV52592_1022 206 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 154175195 Common aroE shikimate 5-dehydrogenase CCV52592_1353 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 154174072 Common - glycosyl transferase, group 1 family protein CCV52592_1232 99 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154175246 Common hisA phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase CCV52592_1199 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 154174970 Common - thioester dehydrase family protein CCV52592_0794 1 None None None 154173660 Common - polyA polymerase family protein CCV52592_1368 208 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 154175144 Common infC translation initiation factor IF-3 CCV52592_0329 210 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 154175179 Common ychF GTP-binding protein YchF CCV52592_1318 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 154174662 Pathogen - hypothetical protein CCV52592_0138 1 None None None 154174634 Common - putative iron compound ABC transporter, ATP-binding protein CCV52592_0601 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 154174974 Common lgt prolipoprotein diacylglyceryl transferase CCV52592_2203 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 154174809 Common - putative integral membrane protein CCV52592_1282 112 COG0679 COG0679, Predicted permeases General function prediction only 154175479 Pathogen - hypothetical protein CCV52592_0570 1 None None None 154175472 Pathogen - putative orphan protein CCV52592_2142 1 None None None 154175167 Common - 3-phosphoshikimate 1-carboxyvinyltransferase CCV52592_0971 42 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 154174932 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase (Ketopantoate hydroxymethyltransferase) CCV52592_0667 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 154175406 Common - ribose-phosphate pyrophosphokinase CCV52592_0207 214 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 154175061 Common fccA flavocytochrome c flavin subunit CCV52592_0919 3 None None None 154175241 Common rarD RarD protein CCV52592_1944 92 COG2962 RarD, Predicted permeases General function prediction only 154173732 Common - iron chelatin ABC transporter, substrate binding protein CCV52592_1612 107 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 154174718 Common - ATP synthase C chain (Lipid-binding protein)(Dicyclohexylcarbodiimide-binding protein) CCV52592_0957 35 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 154173778 Common - hypothetical protein CCV52592_0153 1 None None None 154175149 Common - 4Fe-4S ferredoxin, iron-sulfur binding CCV52592_0010 41 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 154174415 Common - ferric uptake regulation protein (Ferric uptake regulator) CCV52592_1383 182 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 154175169 Common priA primosomal protein N' CCV52592_0321 203 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 154175498 Common cdsA phosphatidate cytidylyltransferase CCV52592_0595 213 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 154174068 Common - zinc transporter ZitB CCV52592_1452 192 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 154174056 Common - heroin esterase CCV52592_1415 117 COG0657 Aes, Esterase/lipase Lipid metabolism 154174425 Common - GntT protein CCV52592_0611 77 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 154175414 Common dnaX DNA polymerase III gamma and tau subunits CCV52592_0862 66 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 154174856 Common - hypothetical protein CCV52592_0513 3 None None None 154175540 Common serB phosphoserine phosphatase CCV52592_1734 9 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 154174900 Common valS valyl-tRNA synthetase CCV52592_1076 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154174523 Common - putative lipopolysaccharide heptosyltransferase III CCV52592_1231 80 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 154174135 Common - OorC subunit of 2-oxoglutarate:acceptor oxidoreductase CCV52592_1877 49 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 154173826 Common - response regulatory protein CCV52592_2119 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 154174460 Common dnaN DNA polymerase III, beta subunit CCV52592_2055 210 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 154174378 Common - hydrolase, TatD family CCV52592_0460 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 154174476 Pathogen - outer membrane lipoprotein MapA CCV52592_1456 1 None None None 154174159 Common pgsA CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase CCV52592_1136 206 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 154174568 Common - nicotinate phosphoribosyltransferase CCV52592_0623 111 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 154173913 Common - Dyp-type peroxidase CCV52592_0389 53 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 154174014 Pathogen - hypothetical protein CCV52592_0149 1 None None None 154174299 Common rimI ribosomal-protein-alanine acetyltransferase CCV52592_0407 124 COG0456 RimI, Acetyltransferases General function prediction only 154174154 Common rfbB dTDP-glucose 4,6-dehydratase CCV52592_0304 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 154175457 Common - hypothetical protein CCV52592_1343 6 None None None 154173931 Common - hypothetical protein CCV52592_1344 2 None None None 154174317 Common - general secretion pathway protein E CCV52592_1964 218 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 154174290 Common - protein YgiW CCV52592_0469 24 COG3111 COG3111, Uncharacterized conserved protein Function unknown 154174867 Common argJ arginine biosynthesis bifunctional protein ArgJ CCV52592_0720 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 154174173 Common - penicillin-binding protein CCV52592_0690 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 154174594 Common - hypothetical protein CCV52592_1641 13 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 154173975 Pathogen - hypothetical protein CCV52592_0762 1 None None None 154175426 Common - thioredoxin family protein CCV52592_1245 232 COG0623 FabI, Enoyl- acyl-carrier-protein 154173842 Common recJ single-stranded-DNA-specific exonuclease RecJ CCV52592_2085 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 154174678 Common - outer membrane fibronectin-binding protein CCV52592_0913 166 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 154173655 Common - cytosine-specific methyltransferase NlaX (M.NlaX) CCV52592_0047 131 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 154174768 Pathogen - hypothetical protein CCV52592_0617 1 None None None 154174908 Common leuA 2-isopropylmalate synthase CCV52592_1193 213 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 154173993 Common ftsY signal recognition particle-docking protein FtsY CCV52592_1395 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 154174855 Common - universal stress protein family CCV52592_0954 36 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 154174572 Common - adenylate kinase (ATP-AMP transphosphorylase) CCV52592_0466 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 154174835 Common - 1-aminocyclopropane-1-carboxylate deaminase CCV52592_0110 13 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 154174369 Common - methylated-DNA--protein-cysteine methyltransferase CCV52592_1412 201 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 154174042 Pathogen - hypothetical protein CCV52592_0600 1 None None None 154174598 Common thiH thiazole biosynthesis protein ThiH CCV52592_1868 55 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 154175330 Common - DNA repair protein RecN (Recombination protein N) CCV52592_1209 46 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 154173987 Common - NifU family protein CCV52592_1004 78 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 154174180 Pathogen - hypothetical protein CCV52592_1294 1 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 154174051 Pathogen - hypothetical protein CCV52592_0883 1 None None None 154175349 Common - ATP synthase gamma chain (ATP synthase F1 sector gammasubunit) CCV52592_1656 180 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 154173867 Common fumC fumarate hydratase, class II CCV52592_1795 214 COG0114 FumC, Fumarase Energy production and conversion 154174954 Pathogen - hypothetical protein CCV52592_0917 1 None None None 154174664 Pathogen - hypothetical protein CCV52592_1461 1 None None None 154175137 Common - thiamine-phosphate kinase CCV52592_1582 50 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 154175508 Common - Na+/H+ antiporter CCV52592_0952 60 COG1926 COG1926, Predicted phosphoribosyltransferases General function prediction only 154174280 Common - hypothetical protein CCV52592_1351 5 None None None 154174828 Common - hydrolase CCV52592_2052 12 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 154174212 Common ftsA cell division protein FtsA CCV52592_1844 174 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 154174459 Common - hypothetical protein CCV52592_0846 4 None None None 154173763 Pathogen - hypothetical protein CCV52592_0316 2 None None None 154174843 Common rseP RIP metalloprotease RseP CCV52592_1135 209 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 154173638 Common - inner membrane protein YicO CCV52592_0221 134 COG2252 COG2252, Permeases General function prediction only 154173836 Common ileS isoleucyl-tRNA synthetase CCV52592_0977 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154174219 Common - glycerate dehydrogenase CCV52592_1540 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 154175006 Common fecB iron chelatin ABC transporter, substrate binding protein CCV52592_1440 113 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 154175346 Common mtnN MTA/SAH nucleosidase CCV52592_1748 102 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 154175319 Common - 4Fe-4S binding domain protein CCV52592_2103 21 COG1148 HdrA, Heterodisulfide reductase, subunit A and related polyferredoxins Energy production and conversion 154173880 Pathogen - hypothetical protein CCV52592_1927 1 None None None 154174803 Common - uracil permease (Uracil transporter) CCV52592_0593 125 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 154175356 Common - dihydrodipicolinate synthase (dhdps) CCV52592_1967 13 COG3267 ExeA, Type II secretory pathway, component ExeA (predicted ATPase) Intracellular trafficking and secretion 154174397 Common - hypothetical protein CCV52592_2174 7 None None None 154174872 Common hypA hydrogenase nickel insertion protein HypA CCV52592_1889 96 COG0375 HybF, Zn finger protein HypA/HybF (possibly regulating hydrogenase expression) General function prediction only 154175386 Pathogen - Hit family protein CCV52592_0032 1 None None None 154174204 Pathogen - hypothetical protein CCV52592_1300 1 None None None 154175194 Common - transcriptional regulator, LuxR family protein CCV52592_0166 138 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 154173805 Common - PP-loop family protein CCV52592_1749 142 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 154174934 Pathogen - hypothetical protein CCV52592_0033 1 None None None 154174740 Common - sodium- and chloride-dependent transporter CCV52592_0960 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 154174922 Common fabD malonyl CoA-acyl carrier protein transacylase CCV52592_1747 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 154173889 Common - peptidase, M23/M37 family CCV52592_0732 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 154174080 Common - putative outer membrane protein CCV52592_1369 1 None None None 154174224 Common - methyltransferase CCV52592_0579 36 COG4797 COG4797, Predicted regulatory domain of a methyltransferase General function prediction only 154173724 Common rho transcription termination factor Rho CCV52592_0274 208 COG1158 Rho, Transcription termination factor Transcription 154174322 Common ligA DNA ligase, NAD-dependent CCV52592_1565 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 154173721 Common - hypothetical protein CCV52592_0011 2 COG1520 COG1520, FOG: WD40-like repeat Function unknown 154174886 Common - 3-oxoacyl-[acyl-carrier-protein] reductase (3-ketoacyl-acyl carrier protein reductase) CCV52592_1164 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 154175239 Common - lyase superfamily CCV52592_0208 201 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 154174237 Common - DNA methylase CCV52592_0941 125 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 154174462 Common - sporulation initiation inhibitor protein soj CCV52592_1731 231 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 154175228 Common - site-specific recombinase, phage integrase family protein CCV52592_0930 69 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 154175083 Common - inner membrane protein, 60 kDa CCV52592_0569 2 None None None 154175286 Common amaB N-carbamoyl-L-amino acid amidohydrolase (AmaB) CCV52592_2110 5 None None None 154173891 Common - malate:quinone oxidoreductase (Malate dehydrogenase[acceptor]) (MQO) CCV52592_1243 84 COG0579 COG0579, Predicted dehydrogenase General function prediction only 154175093 Common terC TerC protein CCV52592_0923 85 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 154175102 Common - preprotein translocase, YajC subunit CCV52592_1316 75 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 154174171 Common ppk polyphosphate kinase CCV52592_0727 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 154174749 Common thrS threonyl-tRNA synthetase CCV52592_0330 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154174273 Common metE 5-methyltetrahydropteroyltriglutamate--homocysteine S-methyltransferase CCV52592_0342 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 154174101 Common - hypothetical protein CCV52592_0193 10 None None None 154175466 Pathogen modB molybdenum ABC transporter, permease protein CCV52592_0955 1 None None None 154175324 Common - Hpt domain protein CCV52592_1924 6 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 154175258 Common - phosphomethylpyrimidine kinase CCV52592_1176 44 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 154174146 Common - methyl-accepting chemotaxis sensory transducer CCV52592_1331 151 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 154174250 Common - hypothetical protein CCV52592_0780 4 None None None 154174087 Common - putative TonB dependent receptor CCV52592_0932 15 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 154174836 Common - tetratricopeptide repeat domain protein CCV52592_2067 15 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 154175230 Common xth exodeoxyribonuclease III CCV52592_0089 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 154174431 Common - prophage Lp2 protein 4 CCV52592_0049 8 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 154175279 Common - hypothetical protein CCV52592_1608 72 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 154174030 Common cvpA CvpA family protein CCV52592_0999 7 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 154175409 Pathogen - putative iron-regulated membrane protein CCV52592_1005 1 None None None 154174943 Common - probable oxidoreductase W CCV52592_1127 174 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 154174513 Common - purine-binding chemotaxis protein CheW CCV52592_1658 136 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 154175440 Common - hypothetical protein CCV52592_1037 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 154174243 Common - hypothetical protein CCV52592_1951 47 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 154175394 Pathogen flgB flagellar basal-body rod protein CCV52592_0441 1 None None None 154175515 Common polA DNA polymerase I superfamily CCV52592_1705 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 154173837 Common - putative ATP/GTP-binding protein CCV52592_1056 2 None None None 154174367 Common - sodium-dependent transporter CCV52592_1818 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 154175270 Common tal transaldolase CCV52592_1660 148 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 154175183 Common ycf cytochrome c biogenesis protein CCV52592_1547 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154174680 Common hemN oxygen-independent coproporphyrinogen III oxidase CCV52592_0159 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 154175018 Common - hypothetical protein CCV52592_0119 33 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 154173746 Common ribD riboflavin biosynthesis protein RibD CCV52592_0359 199 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 154173946 Common - hypothetical protein CCV52592_1718 89 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 154175449 Common expD TonB system transport protein ExbD CCV52592_1241 128 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 154174410 Common - putative nitroimidazole resistance protein CCV52592_1986 14 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 154174512 Common pyrD dihydroorotate oxidase CCV52592_1140 218 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 154173784 Common - hypothetical protein CCV52592_1566 2 None None None 154174604 Common - fumarate reductase respiratory complex, transmembrane subunit CCV52592_2204 10 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 154175297 Common - FlhB domain protein CCV52592_1330 115 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 154174495 Common - integral membrane protein CCV52592_0421 9 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 154174969 Common surE 5'/3'-nucleotidase SurE CCV52592_1650 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 154175481 Common - hypothetical protein CCV52592_1385 14 COG2930 COG2930, Uncharacterized conserved protein Function unknown 154174624 Common - chemotaxis protein PomA CCV52592_1269 94 COG1291 MotA, Flagellar motor component Cell motility and secretion 154175501 Common - 30S ribosomal protein S16 (BS17) CCV52592_0458 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 154174360 Common - hypothetical protein CCV52592_1886 183 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 154174909 Common - beta-lactamase HcpA (Cysteine-rich 28 kDaprotein) CCV52592_0323 79 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154174006 Common - protein TonB CCV52592_1242 28 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 154174259 Common dapA dihydrodipicolinate synthase CCV52592_1138 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 154174314 Common - DNA modification methylase CCV52592_1677 16 COG3392 COG3392, Adenine-specific DNA methylase DNA replication, recombination, and repair 154173936 Common - outer membrane lipoprotein CCV52592_0880 29 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 154174902 Common - MmgE/PrpD family protein CCV52592_1204 63 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 154175261 Common - hypothetical protein CCV52592_1389 45 COG1565 COG1565, Uncharacterized conserved protein Function unknown 154174039 Common - general stress protein 14 (GSP14) CCV52592_0544 68 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 154174330 Pathogen - hypothetical protein CCV52592_0803 3 COG4575 ElaB, Uncharacterized conserved protein Function unknown 154173951 Pathogen - hypothetical protein CCV52592_1620 1 None None None 154174781 Common - general glycosylation pathway protein CCV52592_1216 204 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154174689 Common - lipoprotein 28 CCV52592_1072 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 154174775 Common - phage recombination protein Bet CCV52592_0056 12 None None None 154175086 Common - RDD protein CCV52592_1291 2 None None None 154174308 Common - Rod shape-determining protein MreB CCV52592_0868 235 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 154174164 Pathogen - hypothetical protein CCV52592_0292 1 None None None 154175372 Pathogen - imidazole glycerol phosphate synthase subunit hisf CCV52592_1989 1 None None None 154174896 Common - dihydropteroate synthase CCV52592_1567 217 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 154175332 Common selA L-seryl-tRNA selenium transferase CCV52592_0540 67 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 154173716 Common - flagellar motor protein CCV52592_1191 7 COG1360 MotB, Flagellar motor protein Cell motility and secretion 154174268 Common - collagen triple helix repeat CCV52592_0025 6 None None None 154175043 Common - putative domain of unknown function CCV52592_1682 18 COG0730 COG0730, Predicted permeases General function prediction only 154175284 Common galU UTP-glucose-1-phosphate uridylyltransferase CCV52592_2201 231 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 154174191 Common leuC 3-isopropylmalate dehydratase, large subunit CCV52592_0608 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 154175293 Common - hypothetical protein CCV52592_1542 6 None None None 154174653 Pathogen - hypothetical protein CCV52592_1260 1 None None None 154174124 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase CCV52592_0816 212 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 154174452 Pathogen - hypothetical protein CCV52592_2227 1 None None None 154174029 Pathogen - hypothetical protein CCV52592_0066 1 None None None 154173861 Common - hypothetical protein CCV52592_2030 19 None None None 154174423 Common - protein conserved hypothetical protein CCV52592_0357 165 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 154175197 Common - putative hydrolase, nudix family CCV52592_1571 114 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 154175529 Common aroQ 3-dehydroquinate dehydratase, type II CCV52592_0364 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 154175451 Common - putative cryptic C4-dicarboxylate transporter DcuD CCV52592_0806 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 154174723 Common hslV ATP-dependent protease HslV CCV52592_1974 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 154175110 Pathogen - hypothetical protein CCV52592_2031 1 None None None 154175159 Common - putative prophage LambdaCh01, recombination protein Bet CCV52592_1120 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 154173776 Common - polysaccharide biosynthesis protein CCV52592_1227 37 COG3298 COG3298, Predicted 3'-5' exonuclease related to the exonuclease domain of PolB DNA replication, recombination, and repair 154175071 Common - aspartate racemase subfamily CCV52592_0918 79 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 154175379 Pathogen - hypothetical protein CCV52592_0045 1 None None None 154174972 Common nadE NAD+ synthetase CCV52592_0125 232 COG0171 NadE, NAD synthase Coenzyme metabolism 154173662 Common - NifU family protein CCV52592_1771 126 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 154174813 Common - twin-arginine translocation pathway signal CCV52592_1130 63 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 154174822 Common - diacylglycerol kinase (dagk) (diglyceride kinase)(dgk) CCV52592_0736 42 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 154174324 Common - carboxy--processing protease (C-terminal-processing protease) CCV52592_2006 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 154175469 Common - hypothetical protein CCV52592_0924 1 None None None 154174643 Common pyk pyruvate kinase CCV52592_1356 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 154173669 Common - O-sialoglycoprotein endopeptidase (Glycoprotease) CCV52592_0591 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 154175020 Common - putative DNA methylase CCV52592_1057 127 None None None 154173664 Common - molybdopterin biosynthesis mog protein CCV52592_1069 188 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 154173920 Pathogen - hypothetical protein CCV52592_1946 1 None None None 154173878 Common - cytochrome c oxidase, Cbb3-type, CcoQ subunit CCV52592_0904 1 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 154173902 Common - single-stranded DNA-binding protein (SSB) (Helix-destabilizingprotein) CCV52592_1586 212 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 154174758 Common thiG thiazole biosynthesis protein ThiG CCV52592_1867 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 154174589 Common - biotin carboxylase (Acetyl-CoA carboxylase subunit A) (ACC) CCV52592_0748 236 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 154173830 Common - ABC-transporter periplasmic-binding component CCV52592_0890 113 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 154174791 Common - flavodoxin family protein CCV52592_0646 9 COG4635 HemG, Flavodoxin Energy production and conversion / Coenzyme metabolism 154175460 Common ifcA fumarate reductase flavoprotein subunit CCV52592_0920 17 COG4378 COG4378, Uncharacterized protein conserved in bacteria Function unknown 154174394 Common - hypothetical protein CCV52592_0704 9 None None None 154175218 Common purB adenylosuccinate lyase CCV52592_1984 6 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 154175546 Pathogen - hypothetical protein CCV52592_1604 2 COG4099 COG4099, Predicted peptidase General function prediction only 154174413 Common - general stress protein 14 (GSP14) CCV52592_0505 70 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 154174535 Common - DNA polymerase III subunit alpha CCV52592_0506 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 154174107 Common - polysaccharide biosynthesis protein CCV52592_0560 199 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154173738 Common - transcriptional activator protein CopR CCV52592_0136 216 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154173769 Pathogen - hypothetical protein CCV52592_1162 2 None None None 154173711 Common - ecotin CCV52592_1222 11 COG4574 Eco, Serine protease inhibitor ecotin General function prediction only 154173739 Pathogen - hypothetical protein CCV52592_0756 1 None None None 154175424 Common - hydrogenase maturation protease superfamily CCV52592_1900 63 COG0680 HyaD, Ni,Fe-hydrogenase maturation factor Energy production and conversion 154175527 Common - ATP synthase C chain (Lipid-binding protein)(Dicyclohexylcarbodiimide-binding protein) CCV52592_1299 103 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 154174484 Common infA translation initiation factor IF-1 CCV52592_1012 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 154173696 Common - transmembrane transport protein CCV52592_0931 59 COG1133 SbmA, ABC-type long-chain fatty acid transport system, fused permease and ATPase components Lipid metabolism 154174611 Common - arylsulfotransferase CCV52592_1149 10 None None None 154174618 Common - oxidoreductase CCV52592_2023 157 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 154173792 Pathogen - hypothetical protein CCV52592_1506 2 None None None 154175123 Common - SMR-type multidrug efflux transporter CCV52592_0778 74 COG1345 FliD, Flagellar capping protein Cell motility and secretion 154175494 Common lemA cytoplasmic membrane protein CCV52592_0502 9 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 154174552 Common purN phosphoribosylglycinamide formyltransferase CCV52592_1504 219 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 154174800 Common hypE hydrogenase expression/formation protein HypE CCV52592_1890 116 COG0309 HypE, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 154173964 Common - hypothetical protein CCV52592_1836 26 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154175074 Common - biopolymer transport ExbB protein CCV52592_1091 4 None None None 154173760 Common era GTP-binding protein Era CCV52592_1972 219 COG1159 Era, GTPase General function prediction only 154173786 Common groL chaperonin GroL CCV52592_0308 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 154174798 Common - hypothetical protein CCV52592_0416 16 None None None 154175029 Pathogen ompR response regulator CCV52592_0689 1 None None None 154174738 Common - disulfide bond formation protein, DsbB family CCV52592_1681 14 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 154174580 Common - anthranilate synthase component 1 (Anthranilate synthasecomponent I) CCV52592_1683 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 154173915 Common - putative cytochrome c-type haem-binding periplasmic protein CCV52592_0847 19 None None None 154175311 Common - hypothetical protein CCV52592_0279 5 None None None 154175416 Common - hypothetical protein CCV52592_1895 20 COG4872 COG4872, Predicted membrane protein Function unknown 154174441 Common tyrS tyrosyl-tRNA synthetase CCV52592_0484 239 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154174603 Pathogen - hypothetical protein CCV52592_0842 1 None None None 154173653 Common - hypothetical protein CCV52592_1293 5 None None None 154173844 Common - DNA gyrase subunit B CCV52592_0970 24 COG4648 COG4648, Predicted membrane protein Function unknown 154175111 Common hypE hydrogenase expression/formation protein CCV52592_0635 9 None None None 154175235 Common clpP ATP-dependent Clp protease, proteolytic subunit ClpP CCV52592_1499 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154174765 Common hemE uroporphyrinogen decarboxylase CCV52592_1470 178 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 154174297 Common - multi-copper enzyme maturation ABC-type transport system permease component CCV52592_0666 31 None None None 154174906 Common - hypothetical protein CCV52592_0132 12 None None None 154174851 Common - peptidoglycan-binding domain 1 protein CCV52592_2037 12 COG1462 CsgG, Uncharacterized protein involved in formation of curli polymers Cell envelope biogenesis, outer membrane 154175081 Common - two-component response regulator family protein CCV52592_1618 165 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 154174731 Common rplB ribosomal protein L2 CCV52592_1029 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 154174351 Common - ribosomal large subunit pseudouridine synthase C CCV52592_0674 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 154173953 Common - hypothetical protein CCV52592_0798 7 None None None 154173674 Common - transcriptional regulator, Fur family CCV52592_1672 195 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 154175305 Common - TruB family pseudouridylate synthase (N domain) protein CCV52592_0698 235 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 154174807 Common tmk thymidylate kinase CCV52592_1098 223 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 154174310 Common fhs formate--tetrahydrofolate ligase CCV52592_0358 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 154174522 Pathogen - hypothetical protein CCV52592_1801 1 None None None 154175151 Pathogen - transport protein CCV52592_1767 1 None None None 154174694 Common ilvC ketol-acid reductoisomerase CCV52592_1581 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 154174910 Common hypF [NiFe] hydrogenase maturation protein HypF CCV52592_1898 112 COG0068 HypF, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 154174574 Common rpiB ribose 5-phosphate isomerase B CCV52592_1313 130 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 154173680 Common - transcriptional regulator, AraC family CCV52592_2102 106 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 154175534 Common - succinyl-CoA ligase [ADP-forming] subunit alpha (Succinyl-CoA synthetase subunit alpha) (SCS-alpha) CCV52592_0620 38 COG2107 COG2107, Predicted periplasmic solute-binding protein General function prediction only 154175162 Common - transcriptional regulator, LuxR family CCV52592_1520 147 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 154175539 Common - molybdopterin oxidoreductase domain protein CCV52592_0848 176 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 154175160 Common - transcriptional regulator, ModE family CCV52592_0959 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 154175014 Common sodC copper/zinc superoxide dismutase CCV52592_0788 82 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 154173909 Common - NADP oxidoreductase, coenzyme f420-dependent CCV52592_0326 43 COG2085 COG2085, Predicted dinucleotide-binding enzymes General function prediction only 154173787 Common - Ham1 family CCV52592_0412 233 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 154175104 Common metG methionyl-tRNA synthetase CCV52592_0445 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154174704 Common - putative Chemotaxis protein CheY-like protein CCV52592_1198 224 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 154174140 Common purE phosphoribosylaminoimidazole carboxylase, catalytic subunit CCV52592_0281 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 154173973 Common - 50S ribosomal protein L10 CCV52592_0179 202 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 154174230 Common - putative von Willebrand factor type A domain CCV52592_1750 8 COG4245 TerY, Uncharacterized protein encoded in toxicity protection region of plasmid R478, contains von Willebrand factor (vWF) domain General function prediction only 154174384 Common rplL ribosomal protein L7/L12 CCV52592_0180 207 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 154174278 Common - protein CysQ CCV52592_0577 157 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 154174478 Common - hypothetical protein CCV52592_1455 38 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 154175174 Common - thiol:disulfide interchange protein DsbA CCV52592_1958 172 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 154175204 Common - phosphatase, Ppx/GppA family CCV52592_0037 18 None None None 154175337 Common - putative transducer (chemotactic transducer pcta) CCV52592_0925 8 COG2159 COG2159, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 154174389 Common serA phosphoglycerate dehydrogenase CCV52592_0512 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 154175185 Common tpiA triose-phosphate isomerase CCV52592_1247 215 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 154174058 Common - protein-export membrane protein CCV52592_2113 31 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 154174983 Common - oxidoreductase CCV52592_1378 7 None None None 154175480 Pathogen - hypothetical protein CCV52592_2173 1 None None None 154174376 Common - hypothetical protein CCV52592_0285 121 COG0327 COG0327, Uncharacterized conserved protein Function unknown 154173860 Common - spore coat polysaccharide biosynthesis protein SpsE CCV52592_0565 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 154174622 Common cdsA phosphatidate cytidylyltransferase CCV52592_1174 215 COG4589 COG4589, Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase General function prediction only 154174100 Common - hypothetical protein CCV52592_0254 3 None None None 154175491 Common acrB acriflavine resistance protein CCV52592_0290 161 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 154174924 Common - GTP-binding protein Obg/CgtA CCV52592_1726 249 COG0536 Obg, Predicted GTPase General function prediction only 154175320 Common - putative GTPase CCV52592_1186 227 COG1160 COG1160, Predicted GTPases General function prediction only 154173887 Common - permease, MDR related, probably tetracycline resistance protein CCV52592_0527 208 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154174464 Common - histidinol phosphate phosphatase, HisJ CCV52592_0277 37 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 154175092 Pathogen - 3-isopropylmalate dehydratase large subunit CCV52592_0523 1 None None None 154174884 Common atpC ATP synthase F1, epsilon subunit CCV52592_1739 176 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 154173812 Common - putative flagella basal body P-ring formation protein FlgA CCV52592_1095 6 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 154175099 Common thiS thiamine biosynthesis protein ThiS CCV52592_1865 20 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 154174082 Common alaS alanyl-tRNA synthetase CCV52592_0686 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154174831 Common - transcriptional regulator, ModE family CCV52592_0585 92 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 154175145 Pathogen - hypothetical protein CCV52592_2228 1 None None None 154174956 Common - D-isomer specific 2-hydroxyacid dehydrogenase family protein CCV52592_2124 234 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 154175221 Common luxS S-Ribosylhomocysteinase (LuxS) CCV52592_1053 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 154175433 Common - KWG CCV52592_0976 33 COG4258 COG4258, Predicted exporter General function prediction only 154175004 Common pncB nicotinate phosphoribosyltransferase CCV52592_0508 64 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 154174784 Common - hypothetical protein CCV52592_0934 68 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154175335 Common ackA acetate kinase CCV52592_1158 162 COG0282 ackA, Acetate kinase Energy production and conversion 154173651 Common - flagellar biosynthesis sigma factor FliA CCV52592_0370 135 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 154174747 Pathogen - hypothetical protein CCV52592_2153 1 None None None 154174981 Common panC pantoate--beta-alanine ligase CCV52592_0252 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 154175256 Common rplM ribosomal protein L13 CCV52592_0911 230 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 154175322 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase CCV52592_1576 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 154173726 Common - peptidase, M23/M37 family CCV52592_0480 49 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 154173893 Common - succinate dehydrogenase, iron-sulfur protein subunit CCV52592_1872 199 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 154174746 Common - biotin sulfoxide reductase (BDS reductase) (BSOreductase) CCV52592_0391 143 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 154174586 Common - nitrate transport ATP-binding protein NrtC CCV52592_0422 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 154173807 Common - modification methylase HemK CCV52592_1821 216 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 154175364 Common - transporter, major facilitator family CCV52592_1627 64 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 154174137 Pathogen - hypothetical protein CCV52592_1708 1 None None None 154174687 Common - endonuclease 4 (Endonuclease IV) (EndodeoxyribonucleaseIV) CCV52592_1487 98 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 154175251 Common argC N-acetyl-gamma-glutamyl-phosphate reductase CCV52592_1654 214 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 154174939 Pathogen - hypothetical protein CCV52592_0363 1 None None None 154174365 Common - TonB-dependent outer membrane receptor CCV52592_1051 44 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154174546 Common - thiosulfate reductase CCV52592_1914 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 154174123 Common - ComEA protein CCV52592_0682 10 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 154174167 Common - putative cytochrome C-type haem-binding periplasmic protein CCV52592_0393 25 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 154174078 Common - hypothetical protein CCV52592_1825 26 COG3610 COG3610, Uncharacterized conserved protein Function unknown 154174395 Common trx thioredoxin CCV52592_0836 235 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 154175011 Common - carbonate dehydratase CCV52592_2116 150 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 154175130 Common - putative Signal recognition particle protein (Fifty-four-like protein) CCV52592_0459 138 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 154174044 Pathogen - hypothetical protein CCV52592_0273 1 None None None 154175348 Common - MoeA N- region (domain I and II) protein CCV52592_1093 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 154174629 Common kdsB 3-deoxy-D-manno-octulosonate cytidylyltransferase CCV52592_0131 137 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 154174838 Common folB dihydroneopterin aldolase CCV52592_1694 5 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 154174505 Common modB molybdate ABC transporter, permease protein CCV52592_0552 231 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 154174550 Pathogen - hypothetical protein CCV52592_0205 1 None None None 154173991 Common cybH Ni/Fe-hydrogenase, B-type cytochrome subunit CCV52592_1901 47 COG1969 HyaC, Ni,Fe-hydrogenase I cytochrome b subunit Energy production and conversion 154174819 Common - mechanosensitive ion channel family protein CCV52592_1066 34 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 154174596 Pathogen - hypothetical protein CCV52592_1355 1 None None None 154174763 Common - hypothetical protein CCV52592_1543 2 None None None 154173819 Common mviN integral membrane protein MviN CCV52592_1143 175 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 154174878 Common - hypothetical protein CCV52592_1593 12 None None None 154174706 Common - crispr-associated protein Cas4 CCV52592_1289 34 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 154174879 Pathogen - hypothetical protein CCV52592_1497 1 None None None 154174471 Pathogen - hypothetical protein CCV52592_0016 1 None None None 154174632 Pathogen - hypothetical protein CCV52592_0472 1 None None None 154174282 Common - abc transport permease protein-involved in lipoprotein release CCV52592_0430 192 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 154173898 Pathogen - hypothetical protein CCV52592_2161 1 None None None 154175506 Common - transcriptional regulator, Fur family CCV52592_1721 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 154174053 Common - cytochrome c551 peroxidase (cytochrome cperoxidase) (CCP) CCV52592_1483 91 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 154174245 Common - iron chelatin ABC transporter, substrate binding protein CCV52592_1559 106 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 154173985 Common - putative iron compound ABC transporter, ATP-binding protein CCV52592_0814 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 154174845 Common smpB SsrA-binding protein CCV52592_0695 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 154174606 Common - protein conserved hypothetical protein CCV52592_1755 158 COG1576 COG1576, Uncharacterized conserved protein Function unknown 154173856 Common - hydrogenase-4 component F CCV52592_1038 209 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 154174508 Common - chlorohydrolase CCV52592_0362 102 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 154174186 Common - alpha/beta superfamily hydrolase CCV52592_1613 10 COG0657 Aes, Esterase/lipase Lipid metabolism 154173773 Common - hypothetical protein CCV52592_0907 7 None None None 154173873 Pathogen - hypothetical protein CCV52592_1688 2 None None None 154174773 Pathogen - hypothetical protein CCV52592_1607 1 None None None 154173641 Common - PAS/PAC sensor signal transduction histidine kinase CCV52592_0900 220 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 154174162 Common - deoxyuridine triphosphatase domain protein CCV52592_1648 11 None None None 154174493 Pathogen - hypothetical protein CCV52592_2213 1 None None None 154174339 Common - putative DNA methylase CCV52592_0387 35 COG4646 COG4646, DNA methylase Transcription / DNA replication, recombination, and repair 154173998 Common - archaeal ATPase family CCV52592_0945 20 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 154174761 Pathogen - hypothetical protein CCV52592_1384 1 None None None 154174301 Common psd phosphatidylserine decarboxylase CCV52592_1320 88 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 154175132 Common modD ModD protein CCV52592_1375 194 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 154174215 Common - aminotransferase, class I/II CCV52592_0833 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 154174122 Common - hypothetical protein CCV52592_1590 8 COG4105 ComL, DNA uptake lipoprotein General function prediction only 154175392 Common prfB peptide chain release factor 2 CCV52592_0251 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 154174699 Common prfA peptide chain release factor 1 CCV52592_0740 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 154174345 Common - putative signal transduction protein containing diguanylate cyclase/phosphodiesterase domain CCV52592_1645 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 154173626 Common - hypothetical protein CCV52592_1720 24 COG3875 COG3875, Uncharacterized conserved protein Function unknown 154175139 Common pyrH uridylate kinase CCV52592_0481 227 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 154174252 Common - ABC transporter ATP-binding protein CCV52592_0892 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 154175374 Common - thioredoxin CCV52592_0126 189 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 154175039 Pathogen - hypothetical protein CCV52592_0596 1 None None None 154174515 Common - type II and III secretion system protein CCV52592_1968 144 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 154175442 Common - NH(3)-dependent NAD(+) synthetase CCV52592_0093 21 COG0824 FcbC, Predicted thioesterase General function prediction only 154174089 Pathogen - hypothetical protein CCV52592_0775 1 None None None 154175226 Common - hypothetical protein CCV52592_1399 1 COG2930 COG2930, Uncharacterized conserved protein Function unknown 154174917 Common - hypothetical protein CCV52592_0943 3 None None None 154174193 Common - ABC transporter ATP-binding protein CCV52592_0097 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 154175513 Common - transcriptional regulator, MarR family CCV52592_1937 61 COG1846 MarR, Transcriptional regulators Transcription 154173755 Common rarD RarD protein CCV52592_0796 105 COG2962 RarD, Predicted permeases General function prediction only 154175400 Common - hypothetical protein CCV52592_0694 6 None None None 154174374 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase CCV52592_1092 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 154174285 Common - hypothetical protein CCV52592_0008 13 None None None 154173938 Common - hypothetical protein CCV52592_2047 11 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 154175268 Common copA cation-transporting ATPase, P-type CCV52592_0854 49 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 154175026 Common - Sec-independent protein translocase protein TatC CCV52592_2008 160 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 154174946 Common - hypothetical protein CCV52592_0700 7 None None None 154175354 Common fliG flagellar motor switch protein FliG CCV52592_1669 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 154173839 Common - flavocytochrome c flavin subunit CCV52592_0002 199 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 154175237 Pathogen dhs 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase CCV52592_0024 1 None None None 154175067 Common - DJ-1 family protein CCV52592_0509 143 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 154174027 Common - inner membrane symporter YgjU CCV52592_0702 156 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 154175419 Common hisH imidazole glycerol phosphate synthase, glutamine amidotransferase subunit CCV52592_1200 216 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 154174562 Pathogen - hypothetical protein CCV52592_2237 1 None None None 154175384 Common flgK flagellar hook-associated protein FlgK CCV52592_0786 105 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 154175180 Common - hypothetical protein CCV52592_0946 45 COG3663 Mug, G:T/U mismatch-specific DNA glycosylase DNA replication, recombination, and repair 154175002 Common panD aspartate 1-decarboxylase CCV52592_0074 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 154174428 Common rplA ribosomal protein L1 CCV52592_0178 237 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 154173622 Common - lipoprotein CCV52592_0259 44 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 154174447 Common - cell volume regulation protein A CCV52592_0757 132 COG3263 COG3263, NhaP-type Na+/H+ and K+/H+ antiporters with a unique C-terminal domain Inorganic ion transport and metabolism 154175389 Common frr ribosome recycling factor CCV52592_2111 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 154174993 Common nhaC Na+/H+ antiporter NhaC CCV52592_0184 59 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 154173652 Common - 2-methylthioadenine synthetase CCV52592_0253 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 154175163 Common - cell division protein FtsY CCV52592_0268 149 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 154174674 Common - iron ABC transporter, solute-binding protein CCV52592_0815 75 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 154175216 Common - 50S ribosomal protein L10 CCV52592_1528 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 154175402 Common - translocator protein, LysE family CCV52592_1363 108 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 154175537 Common modB molybdate ABC transporter, permease protein CCV52592_0581 231 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 154175522 Common - putative alkyl-dihydroxyacetone phosphate synthase CCV52592_1462 217 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 154173967 Common - phosphate transporter family protein CCV52592_1957 172 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 154173774 Common - bacterial regulatory protein, AsnC family:Bacterial regulatory protein, GntR family CCV52592_1710 129 COG1802 GntR, Transcriptional regulators Transcription 154175076 Common fliH putative flagellar assembly protein CCV52592_1723 97 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 154175458 Common proP ProP protein CCV52592_0432 25 COG3470 Tpd, Uncharacterized protein probably involved in high-affinity Fe2+ transport Inorganic ion transport and metabolism 154175423 Common - putative 4-hydroxybenzoate polyprenyltransferase CCV52592_0818 161 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 154174386 Common dapF diaminopimelate epimerase CCV52592_0348 200 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 154173824 Common - trap dicarboxylate transporter, dctm subunit CCV52592_0962 125 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 154174256 Common yhbN cell envelope biogenesis protein YhbN CCV52592_0454 9 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 154174407 Common acpS holo-(acyl-carrier-protein) synthase CCV52592_1391 112 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 154175418 Pathogen - ribonuclease CCV52592_1467 1 None None None 154175476 Pathogen tlpB methyl-accepting chemotaxis protein CCV52592_0499 1 None None None 154174702 Pathogen - hypothetical protein CCV52592_1851 1 None None None 154174721 Common - TonB-dependent receptor domain protein CCV52592_1110 118 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154174403 Common rimM 16S rRNA processing protein RimM CCV52592_0678 28 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 154174927 Common - multi-sensor signal transduction histidine kinase CCV52592_1804 211 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 154173871 Common - B-glycosyltransferase, glycosyltransferase family 2 protein CCV52592_0298 119 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 154173780 Common yaeT outer membrane protein assembly complex, YaeT protein CCV52592_1757 160 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 154175223 Common prs ribose-phosphate pyrophosphokinase subfamily CCV52592_1446 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 154173741 Common - twin-arginine translocation protein TatA/E CCV52592_1255 7 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 154174443 Pathogen - hypothetical protein CCV52592_2238 1 None None None 154174020 Common - putative TonB-dependent colicin receptor protein CCV52592_1047 35 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 154174733 Common - hypothetical protein CCV52592_1486 5 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 154174156 Common - putative oxygen-independent coproporphyrinogen III oxidase CCV52592_1573 205 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 154175187 Common pipD pathogenicity island encoded protein: SPI3 CCV52592_1815 147 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 154175411 Common metK methionine adenosyltransferase CCV52592_0703 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 154175244 Common trpF N-(5'phosphoribosyl)anthranilate isomerase CCV52592_1685 122 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 154174472 Common sucD succinate-CoA ligase, alpha subunit subfamily CCV52592_1881 218 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 154174997 Common - hypothetical protein CCV52592_1807 9 None None None 154175150 Common rpsO 30S ribosomal protein S15 CCV52592_2211 53 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 154174340 Common - sodium-dependent tyrosine transporter CCV52592_0645 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 154173639 Common rpoA DNA-directed RNA polymerase, alpha subunit CCV52592_1008 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 154173817 Common - FAD-dependent oxidoreductase CCV52592_0817 93 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 154174313 Common - sensor histidine kinase CCV52592_0137 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154174732 Common - Na+/H+ antiporter CCV52592_0578 116 COG0025 NhaP, NhaP-type Na+/H+ and K+/H+ antiporters Inorganic ion transport and metabolism 154174037 Common - DNA-binding response regulator CCV52592_1280 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154175502 Common - hypothetical protein CCV52592_1443 3 None None None 154174294 Common pyrG CTP synthase CCV52592_2084 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 154173892 Common gyrB DNA gyrase, B subunit CCV52592_2054 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 154174085 Common - multidrug resistance protein YkkD CCV52592_1182 23 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 154175453 Common - NikR C nickel binding domain family CCV52592_1897 65 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 154174656 Common - putative endoribonuclease L-PSP CCV52592_1208 177 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 154175208 Common - hypothetical protein CCV52592_1643 6 None None None 154174054 Common - methyl-accepting chemotaxis protein CCV52592_1962 75 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 154175211 Common - cytochrome C biogenesis protein transmembrane region CCV52592_0145 154 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 154175308 Pathogen - hypothetical protein CCV52592_2129 1 None None None 154175382 Common modA molybdenum ABC transporter, periplasmic molybdate-binding protein CCV52592_0958 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 154174421 Common - cytosol aminopeptidase (Leucine aminopeptidase) (LAP)(Leucyl aminopeptidase) CCV52592_1317 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 154173751 Common - trimethylamiNe-n-oxide reductase 1 (tmaoreductase 1) (trimethylamine oxidase 1) CCV52592_2044 169 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 154173955 Common - protein of unknown function, DUF CCV52592_0653 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 154174739 Common - exporter protein CCV52592_1727 109 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 154174904 Common - hypothetical protein CCV52592_0819 4 None None None 154174923 Common - peptidyl-prolyl cis-trans isomerase (PPIase) (Rotamase) CCV52592_1036 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 154173979 Common - hypothetical protein CCV52592_1841 11 None None None 154173659 Common - formate dehydrogenase, cytochrome B subunit CCV52592_1778 64 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 154174824 Pathogen - hypothetical protein CCV52592_0388 1 None None None 154174178 Common - major outer membrane protein CCV52592_0195 3 None None None 154173863 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase CCV52592_0322 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 154175336 Pathogen - hypothetical protein CCV52592_1870 1 None None None 154173720 Common lpxB lipid-A-disaccharide synthase CCV52592_1652 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 154174859 Common - ABC transporter, permease protein, FecCD family CCV52592_1614 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 154174093 Common petA ubiquinol-cytochrome c reductase, iron-sulfur subunit CCV52592_1814 117 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 154175133 Pathogen - fructose-bisphosphate aldolase CCV52592_0739 1 None None None 154175080 Pathogen - MraY CCV52592_1087 1 None None None 154175156 Pathogen - hypothetical protein CCV52592_0027 1 None None None 154175430 Common - hypothetical protein CCV52592_1568 9 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 154174620 Common - drug resistance transporter CCV52592_0947 154 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 154175125 Common - NeuB3 CCV52592_0939 48 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 154174685 Common - hypothetical protein CCV52592_0669 32 COG2863 COG2863, Cytochrome c553 Energy production and conversion 154173929 Common - putative transducer CCV52592_2035 147 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 154174805 Common - biopolymer transport ExbD protein CCV52592_1049 136 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 154174978 Common algI alginate O-acetylation protein CCV52592_1364 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 154174329 Pathogen - hypothetical protein CCV52592_0313 1 None None None 154174892 Common - MoeB/ThiF family protein CCV52592_0001 99 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 154173789 Common - chaperone ClpB 1 CCV52592_1904 230 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 154174198 Common - hypothetical protein CCV52592_0899 30 COG2836 COG2836, Uncharacterized conserved protein Function unknown 154173672 Common - putative methyl-accepting chemotaxis sensory transducer with Pas/Pac sensor CCV52592_1919 17 None None None 154175054 Common rpsH ribosomal protein S8 CCV52592_1019 222 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 154174985 Common lpxK tetraacyldisaccharide-1-P 4'-kinase CCV52592_0127 35 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 154175105 Common - DNA modification methylase (adenine-specific methyltransferase) CCV52592_1716 120 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 154175077 Common - DNA polymerase III subunit beta CCV52592_1311 220 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 154174111 Common - hypothetical protein CCV52592_1626 12 COG3015 CutF, Uncharacterized lipoprotein NlpE involved in copper resistance Cell envelope biogenesis, outer membrane / Inorganic ion transport and metabolism 154175318 Common - nitric oxide reductase large subunit CCV52592_1444 74 COG3189 COG3189, Uncharacterized conserved protein Function unknown 154175176 Common nhaC Na+/H+ antiporter NhaC CCV52592_1535 5 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 154174691 Common - transcriptional regulator, LysR family CCV52592_1787 193 COG0583 LysR, Transcriptional regulator Transcription 154174482 Common - uridine diphosphate glucose pyrophosphatase CCV52592_0730 37 None None None 154174187 Common - RDD protein CCV52592_2108 7 COG1714 COG1714, Predicted membrane protein/domain Function unknown 154173632 Common - iron-sulfur protein CCV52592_0006 59 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 154174725 Common - major outer membrane protein CCV52592_0123 4 None None None 154173694 Pathogen - hypothetical protein CCV52592_0076 1 None None None 154175273 Common - putative cytochrome c CCV52592_2042 37 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 154174816 Common - histidine triad nucleotide-binding protein 2 (hint-2)(hint-3) CCV52592_0519 232 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 154175496 Common fliS flagellar protein FliS CCV52592_0777 74 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 154174118 Common - pirin family protein CCV52592_1938 147 COG1741 COG1741, Pirin-related protein General function prediction only 154173910 Pathogen - hypothetical protein CCV52592_1445 1 None None None 154175048 Pathogen - hypothetical protein CCV52592_1170 2 None None None 154174639 Common - CmeA CCV52592_1776 168 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 154174366 Common - transporter, Ni2+-Co2+ transporter CCV52592_0096 26 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 154174554 Common - hypothetical protein CCV52592_1840 4 None None None 154174277 Common - nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase CCV52592_2092 25 COG0388 COG0388, Predicted amidohydrolase General function prediction only 154173793 Pathogen - putative resolvase CCV52592_0036 1 None None None 154175051 Pathogen - hypothetical protein CCV52592_0099 1 None None None 154175097 Common lepB signal peptidase I CCV52592_0800 177 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 154175291 Common - chad domain family CCV52592_1673 43 COG5607 COG5607, Uncharacterized conserved protein Function unknown 154175027 Common lnt apolipoprotein N-acyltransferase CCV52592_0705 73 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 154174979 Pathogen - hypothetical protein CCV52592_0048 1 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 154174666 Pathogen - hypothetical protein CCV52592_0343 1 None None None 154174709 Common mrp Mrp protein CCV52592_0204 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 154173922 Common - peptidase M48, Ste24p CCV52592_0655 125 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 154173699 Common - putative NAD(P)H nitroreductase CCV52592_1939 93 COG0778 NfnB, Nitroreductase Energy production and conversion 154175012 Common - bacterial flagellin N-terminus domain protein CCV52592_1295 71 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 154175113 Common fmt methionyl-tRNA formyltransferase CCV52592_1729 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 154174630 Common recR recombination protein RecR CCV52592_1358 203 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 154174614 Common hemD uroporphyrinogen-III synthase CCV52592_0948 14 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 154173666 Common - TrkA domain protein CCV52592_1437 10 COG3400 COG3400, Uncharacterized protein conserved in bacteria Function unknown 154174796 Common - hypothetical protein CCV52592_0256 4 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 154174266 Pathogen - hypothetical protein CCV52592_0528 1 None None None 154173809 Common - protein TolB CCV52592_1743 124 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 154175532 Common purB adenylosuccinate lyase CCV52592_0005 230 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 154173679 Common - peptidase family C69 CCV52592_0344 25 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 154174005 Pathogen - hypothetical protein CCV52592_0345 1 None None None 154175090 Common coaE dephospho-CoA kinase CCV52592_0349 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 154173908 Common lepA GTP-binding protein LepA CCV52592_1454 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 154174756 Common purF amidophosphoribosyltransferase CCV52592_0845 241 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 154175040 Common - membrane protein CCV52592_0332 36 None None None 154174713 Common - ABC transporter, permease protein, FecCD family CCV52592_0891 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 154174076 Common - hypothetical protein CCV52592_1780 24 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 154174412 Common - hypothetical protein CCV52592_0895 3 None None None 154175487 Common - crispr-associated protein Cas2 CCV52592_0303 191 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 154174383 Pathogen - hypothetical protein CCV52592_0064 1 None None None 154175203 Common - oxidoreductase, aldo/keto reductase family CCV52592_2022 199 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 154174011 Common - NADH-quinone oxidoreductase subunit h (nadhdehydrogenase i subunit h) (ndh-1 subunit h) CCV52592_1522 187 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 154174334 Common rarD RarD protein CCV52592_0795 99 COG2962 RarD, Predicted permeases General function prediction only 154175036 Common - 1-deoxy-d-xylulose-5-phosphate synthase CCV52592_1722 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 154175140 Common mreC rod shape-determining protein MreC CCV52592_0869 12 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 154175519 Common flgD hook assembly protein, flagella CCV52592_1758 182 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 154173677 Common atpD ATP synthase F1, beta subunit CCV52592_1738 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 154173757 Common - hypothetical protein CCV52592_0282 4 None None None 154174947 Pathogen - Tat (twin-arginine translocation) pathway signal sequence domain protein CCV52592_0271 1 None None None 154175327 Common flgE flagellar hook protein FlgE CCV52592_2239 168 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 154174229 Common rpsB ribosomal protein S2 CCV52592_1262 226 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 154175032 Pathogen - type IV pilus assembly protein PilZ CCV52592_1697 1 None None None 154174503 Common - bacterial Peptidase A24 N- domain family CCV52592_1264 128 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 154175370 Common - phospholipase A CCV52592_0521 24 None None None 154174769 Common - alpha/beta hydrolase fold CCV52592_1155 22 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154174192 Common flgE flagellar hook protein FlgE CCV52592_2040 127 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 154174131 Common - putative periplasmic protein CCV52592_0922 35 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 154174671 Common - RDD protein CCV52592_0950 19 COG1714 COG1714, Predicted membrane protein/domain Function unknown 154175017 Common - hypothetical protein CCV52592_1466 8 None None None 154173928 Common - DNA integration/recombination/inversion protein CCV52592_0063 113 COG0582 XerC, Integrase DNA replication, recombination, and repair 154174698 Common - LemA protein CCV52592_0634 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 154174065 Common fliF flagellar M-ring protein FliF CCV52592_1668 128 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 154174608 Common - hypothetical protein CCV52592_0974 22 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 154173810 Common - DnaJ domain protein CCV52592_1837 177 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 154174222 Common kdsA 3-deoxy-8-phosphooctulonate synthase CCV52592_1184 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 154174319 Common mrdB rod shape-determining protein RodA CCV52592_0473 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 154175360 Common - diguanylate cyclase CCV52592_1210 200 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 154174915 Common - thiol peroxidase (Scavengase P20) CCV52592_0642 100 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 154173949 Common - hypothetical protein CCV52592_0896 11 COG2952 COG2952, Uncharacterized protein conserved in bacteria Function unknown 154173643 Common - 3-oxoacyl-[acyl-carrier-protein] synthase 3 CCV52592_1699 219 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 154174217 Common - hypothetical protein CCV52592_0257 4 None None None 154174364 Common - prevent-host-death family protein CCV52592_2220 8 None None None 154173750 Common - NADH-quinone oxidoreductase chain k (NADH dehydrogenase i, chain k) (ndh-1, chain k) CCV52592_1519 163 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 154175178 Common - ribonuclease 3 (Ribonuclease III) (RNase III) CCV52592_2115 137 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 154174491 Pathogen - hypothetical protein CCV52592_0030 1 None None None 154174960 Common - hypothetical protein CCV52592_2049 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 154174434 Common - hydrogenase-4 component E CCV52592_1039 38 COG4237 HyfE, Hydrogenase 4 membrane component (E) Energy production and conversion 154174961 Common holB DNA polymerase III delta prime subunit CCV52592_0928 36 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 154175398 Common - proton-translocating NADH-quinone oxidoreductase, chain n subfamily CCV52592_1516 210 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 154175436 Common - flagella basal body rod protein CCV52592_0105 125 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 154174498 Common - hypothetical protein CCV52592_0662 12 None None None 154174304 Common - RNA methyltransferase, TrmH family, group 3 CCV52592_0830 216 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 154174576 Common prmA ribosomal protein L11 methyltransferase CCV52592_1197 175 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 154174786 Common - DNA-binding response regulator CCV52592_1917 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154174149 Common - hypothetical protein CCV52592_1971 5 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 154174771 Common - RNA-uridine isomerase CCV52592_1113 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 154174302 Common - hypothetical protein CCV52592_1381 2 None None None 154175504 Common - imidazoleglycerol phosphate dehydratase CCV52592_1215 213 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154173942 Pathogen - hypothetical protein CCV52592_2166 1 None None None 154174142 Common exbB TonB-system energizer ExbB CCV52592_1240 148 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 154174035 Common - acetyltransferase, gnat family CCV52592_2150 22 COG0456 RimI, Acetyltransferases General function prediction only 154173624 Common - YbaK/prolyl-tRNA synthetase associated region CCV52592_1112 26 COG2606 EbsC, Uncharacterized conserved protein Function unknown 154174965 Common - hypothetical protein CCV52592_0787 22 None None None 154175391 Common - nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase CCV52592_2086 42 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154174279 Common - permeases of the drug/metabolite transporter CCV52592_1480 108 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 154174668 Pathogen - hypothetical protein CCV52592_0165 1 None None None 154174557 Pathogen - hypothetical protein CCV52592_1532 1 None None None 154174950 Common - methionyl-tRNA formyltransferase CCV52592_1664 25 COG0795 COG0795, Predicted permeases General function prediction only 154175342 Common - hypothetical protein CCV52592_1482 25 None None None 154173686 Common - hypothetical protein CCV52592_0829 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 154174801 Common - TonB-dependent haem/haemoglobin receptor CCV52592_1239 90 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154175362 Common - tonB-dependent receptor CCV52592_0651 125 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 154174877 Common - 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase DapD CCV52592_0213 41 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 154174951 Common - ribosomal protein S10p/S20e CCV52592_2236 246 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 154175037 Common - MauM/NapG family ferredoxin-type protein CCV52592_1929 63 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 154174392 Common - transcriptional regulator, AraC family CCV52592_1805 76 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 154173983 Common - ABC transporter ATP-binding protein CCV52592_2198 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 154174201 Common hypB hydrogenase accessory protein HypB CCV52592_1893 135 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 154173748 Common pyrE orotate phosphoribosyltransferase CCV52592_2109 96 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 154175089 Common hisD histidinol dehydrogenase CCV52592_0109 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 154174847 Common - hydrogenase-4 component H CCV52592_1636 64 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 154174208 Common thyX thymidylate synthase, flavin-dependent CCV52592_2063 39 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 154174864 Common - (R)-2-hydroxyglutaryl-CoA dehydratase activator (2-hydroxyglutaryl-CoA dehydratase component A) CCV52592_0874 65 COG1924 COG1924, Activator of 2-hydroxyglutaryl-CoA dehydratase (HSP70-class ATPase domain) Lipid metabolism 154174528 Common pheS phenylalanyl-tRNA synthetase, alpha subunit CCV52592_0518 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 154174091 Pathogen - hypothetical protein CCV52592_0411 1 None None None 154174703 Common - UDP-glucose 4-epimerase CCV52592_0877 3 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154174648 Common rfbA glucose-1-phosphate thymidylyltransferase CCV52592_0305 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 154174744 Common dnaG DNA primase CCV52592_2069 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 154173650 Common - hypothetical protein CCV52592_0377 3 None None None 154173634 Common moaC molybdenum cofactor biosynthesis protein C CCV52592_0664 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 154174958 Common - DNA-binding response regulator CCV52592_1401 1 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 154173996 Common - hypothetical protein CCV52592_0112 4 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 154174356 Pathogen - hypothetical protein CCV52592_1854 1 None None None 154174938 Common - metalloid reductase RarA CCV52592_2207 7 None None None 154174959 Common thiL thiamine-monophosphate kinase CCV52592_0773 193 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 154174560 Common - general glycosylation pathway protein CCV52592_1213 7 COG1287 COG1287, Uncharacterized membrane protein, required for N-linked glycosylation General function prediction only 154174984 Pathogen - ModE repressor domain protein CCV52592_0417 1 None None None 154173885 Common - two-component regulator CCV52592_1693 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154173736 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 family protein CCV52592_0760 151 COG0546 Gph, Predicted phosphatases General function prediction only 154175377 Common secA preprotein translocase, SecA subunit CCV52592_1859 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 154174287 Common argF ornithine carbamoyltransferase CCV52592_0157 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 154174641 Common - hypothetical protein CCV52592_1160 22 None None None 154174125 Common gyrA DNA gyrase, A subunit CCV52592_1459 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 154175049 Common - periplasmic binding protein CCV52592_1611 98 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 154174083 Common - chain X CCV52592_1052 20 COG3016 PhuW, Uncharacterized iron-regulated protein Function unknown 154173772 Common nifS cysteine desulfurase, NifS family CCV52592_1770 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 154175255 Pathogen - porphobilinogen deaminase CCV52592_1588 1 None None None 154174207 Common - phenylacrylic acid decarboxylase (PAD) CCV52592_1096 151 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 154174455 Common - putative integral membrane protein CCV52592_1649 3 None None None 154174840 Common - general stress protein 14 (GSP14) CCV52592_2172 76 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 154174248 Common - amino acid ABC transporter, permease protein, His/Glu/Gln/Arg/opine family CCV52592_0493 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 154175421 Common - RNA-binding protein CCV52592_1163 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 154174882 Pathogen - hypothetical protein CCV52592_1850 2 COG1289 COG1289, Predicted membrane protein Function unknown 154174254 Common - hypothetical protein CCV52592_1826 6 None None None 154174751 Common - sensor histidine kinase, PAS domain CCV52592_1764 165 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 154173974 Common - hydrolase, carbon-nitrogen family CCV52592_0083 199 COG0388 COG0388, Predicted amidohydrolase General function prediction only 154174379 Common murI glutamate racemase CCV52592_1992 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 154175428 Common - FdhC protein CCV52592_1753 7 None None None 154174987 Common - PglC CCV52592_1860 150 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 154173629 Common - HuvX protein CCV52592_2043 18 COG3721 HugX, Putative heme iron utilization protein Inorganic ion transport and metabolism 154173689 Common rpoN RNA polymerase sigma-54 factor CCV52592_1983 143 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 154175298 Pathogen - tRNA(Ile)-lysidine synthase (tRNA(Ile)-lysidinesynthetase) (tRNA(Ile)-2-lysyl-cytidine synthase) CCV52592_0843 1 None None None 154174158 Common tuf translation elongation factor Tu CCV52592_0173 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 154175413 Common - hypothetical protein CCV52592_1285 63 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 154174238 Pathogen - hypothetical protein CCV52592_1281 1 None None None 154174888 Common - thioesterase superfamily CCV52592_0973 52 COG0824 FcbC, Predicted thioesterase General function prediction only 154174853 Common - GatB/Yqey family protein CCV52592_1959 152 COG1610 COG1610, Uncharacterized conserved protein Function unknown 154175201 Common - holliday junction ATP-dependent DNA helicase RuvA CCV52592_1954 10 None None None 154174832 Common - sensor histidine kinase CCV52592_1279 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154174117 Common rpmE ribosomal protein L31 CCV52592_0828 179 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 154173895 Pathogen - hypothetical protein CCV52592_2078 1 None None None 154175275 Common - 3-isopropylmalate dehydratase small subunit CCV52592_0685 1 None None None 154174176 Common - cytochrome c-553 (cytochrome c553) (Low-potential cytochromec) CCV52592_0241 26 COG2863 COG2863, Cytochrome c553 Energy production and conversion 154175530 Common - copper-translocating P-type ATPase CCV52592_0531 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154175206 Common hydB quinone-reactive Ni/Fe hydrogenase, large subunit CCV52592_0647 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 154173710 Common yajC preprotein translocase, YajC subunit CCV52592_0706 169 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 154174780 Common - inner membrane protein OxaA CCV52592_1831 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 154174995 Common carB carbamoyl-phosphate synthase, large subunit CCV52592_0870 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 154174821 Pathogen - hypothetical protein CCV52592_1819 1 None None None 154174991 Common - hypothetical protein CCV52592_1809 3 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 154173684 Common - membrane protein CCV52592_0090 63 COG1971 COG1971, Predicted membrane protein Function unknown 154174315 Common ccoG cytochrome c oxidase accessory protein CcoG CCV52592_1549 84 COG0348 NapH, Polyferredoxin Energy production and conversion 154173779 Common argS arginyl-tRNA synthetase CCV52592_1254 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 154173657 Common rpsL ribosomal protein S12 CCV52592_0186 231 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 154174735 Common - biotin-[acetyl-CoA-carboxylase] ligase CCV52592_1730 96 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 154174258 Common lys1 saccharopine dehydrogenase CCV52592_0415 51 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 154173977 Pathogen - glycosyl transferase, group 1 family protein CCV52592_0300 1 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154175242 Common - nucleoside diphosphate kinase CCV52592_1691 183 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 154174914 Common - putative two component sensor kinase CCV52592_0849 210 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 154174700 Common - hypothetical protein CCV52592_1525 6 None None None 154174683 Common - TPR repeat-containing protein CCV52592_1745 12 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 154174658 Common - probable pyridine nucleotide-disulfide oxidoreductase YkgC CCV52592_0248 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 154175165 Common flgI flagellar P-ring protein FlgI CCV52592_0782 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 154173933 Common - OmpA/MotB CCV52592_1270 145 COG1360 MotB, Flagellar motor protein Cell motility and secretion 154175063 Common - antibiotic biosynthesis monooxygenase domain protein CCV52592_2026 6 COG1359 COG1359, Uncharacterized conserved protein Function unknown 154175484 Common - hypothetical protein CCV52592_0588 61 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 154173969 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase CCV52592_1430 175 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 154174627 Common - anaerobic dimethyl sulfoxide reductase subunit A CCV52592_2107 181 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 154174449 Common napA periplasmic nitrate reductase, large subunit CCV52592_1928 176 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 154173848 Common - periplasmic binding protein CCV52592_0603 75 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 154173822 Common - hypothetical protein CCV52592_0398 7 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 154175127 Common - putative DNA-binding response regulator CCV52592_1961 102 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 154174445 Common murD UDP-N-acetylmuramoylalanine--D-glutamate ligase CCV52592_1046 205 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 154173717 Common - glutathionylspermidine synthase family protein CCV52592_1541 53 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 154174372 Common - inner membrane protein YfcA CCV52592_0789 160 COG0730 COG0730, Predicted permeases General function prediction only 154174066 Common - ExsB protein CCV52592_0448 177 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 154173912 Common fliQ flagellar biosynthetic protein FliQ CCV52592_0619 28 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 154174047 Common - succinyl-CoA synthetase beta chain (SCS-alpha)(Vegetative protein 63) (VEG63) CCV52592_1882 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 154174474 Common - DoxX family protein CCV52592_0183 53 COG2259 COG2259, Predicted membrane protein Function unknown 154174292 Common - hypothetical protein CCV52592_1906 157 COG1496 COG1496, Uncharacterized conserved protein Function unknown 154175520 Common yciA acyl-CoA thioester hydrolase CCV52592_1751 7 None None None 154174591 Common - two-component response regulator CCV52592_1806 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154174405 Common - PepSY-associated TM helix family CCV52592_1810 20 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 154174544 Common - diguanylate cyclase CCV52592_1500 17 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 154175225 Common - copper-translocating P-type ATPase CCV52592_0267 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 154174388 Common - transport protein CCV52592_2039 30 COG2056 COG2056, Predicted permease General function prediction only 154174707 Common pcm protein-L-isoaspartate O-methyltransferase CCV52592_2091 153 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 154174409 Common - flagellar hook assembly protein CCV52592_2048 108 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 154174018 Common - hypothetical protein CCV52592_1569 7 None None None 154175009 Pathogen - competence/damage-inducible domain protein CCV52592_0385 1 None None None 154173917 Common rplO ribosomal protein L15 CCV52592_1015 173 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 154174711 Common - metallophosphoesterase CCV52592_1655 13 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 154174061 Pathogen - hypothetical protein CCV52592_2232 1 None None None 154173782 Common - 5,10-methenyltetrahydrofolate synthetase CCV52592_1397 37 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 154174754 Common hisC histidinol-phosphate aminotransferase CCV52592_1667 236 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 154175025 Common - thioesterase family protein CCV52592_0122 10 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 154175464 Common - anthranilate synthase component I and chorismate binding protein CCV52592_0325 43 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 154173796 Pathogen - hypothetical protein CCV52592_0146 1 None None None 154174271 Common fbp fructose-1,6-bisphosphatase CCV52592_0443 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 154174320 Common aroC chorismate synthase CCV52592_2064 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 154174128 Common trmD tRNA (guanine-N1)-methyltransferase CCV52592_0679 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 154175265 Common secF protein-export membrane protein CCV52592_1314 4 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 154174715 Common nth endonuclease III CCV52592_0115 238 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 154174605 Common - hypothetical protein CCV52592_0543 25 COG1427 COG1427, Predicted periplasmic solute-binding protein General function prediction only 154173829 Common - S4 domain protein CCV52592_1980 36 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 154175367 Common - hypothetical protein CCV52592_0222 54 COG2236 COG2236, Predicted phosphoribosyltransferases General function prediction only 154174676 Pathogen - hypothetical protein CCV52592_1168 1 None None None 154174103 Common argH argininosuccinate lyase CCV52592_0522 230 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 154174616 Common - cation ABC transporter, permease protein CCV52592_0098 191 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 154173708 Common - aminobenzoyl-glutamate utilization protein A CCV52592_2071 165 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 154173924 Common - hypothetical protein CCV52592_0249 5 None None None 154174003 Common - DNA ligase (Polydeoxyribonucleotide synthase [ATP]) CCV52592_1225 44 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 154174264 Common - IroE protein CCV52592_1979 38 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 154173668 Common - putative response regulator ArlR CCV52592_0337 136 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 154174646 Common - peptidase U32 CCV52592_0280 141 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 154175238 Common dprA DNA processing chain A CCV52592_1471 121 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 154174450 Common mgtE magnesium transporter CCV52592_0731 170 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 154174332 Common - GTP-binding protein CCV52592_2209 48 COG3596 COG3596, Predicted GTPase General function prediction only 154174480 Common rplU ribosomal protein L21 CCV52592_1724 181 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 154173960 Common - anthranilate synthase component II CCV52592_1684 240 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 154175147 Common - hydrolase, carbon-nitrogen family CCV52592_0340 34 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 154174556 Common ybaK YbaK/ebsC protein CCV52592_1631 113 COG2606 EbsC, Uncharacterized conserved protein Function unknown 154174234 Common - D-alanine aminotransferase CCV52592_1852 196 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 154175158 Common rplQ ribosomal protein L17 CCV52592_1007 215 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 154175542 Common - membrane protein CCV52592_1698 225 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 154175107 Common - ribosomal protein L22 CCV52592_1070 110 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 154175444 Pathogen - RNA polymerase sigma factor RpoD CCV52592_0746 1 None None None 154174196 Common - oxidoreductase, short chain dehydrogenase/reductase family CCV52592_1418 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 154173765 Common - molybdate metabolism regulator CCV52592_1411 7 COG4884 COG4884, Uncharacterized protein conserved in bacteria Function unknown 154173670 Common - similarity to mvin protein CCV52592_1491 49 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 154174417 Common truD tRNA pseudouridine synthase D CCV52592_0774 87 COG0585 COG0585, Uncharacterized conserved protein Function unknown 154175116 Common tcmP TcmP CCV52592_0495 181 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 154175248 Common - hypothetical protein CCV52592_0062 11 None None None 154174810 Common - chemotaxis protein CheA CCV52592_1657 224 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 154175056 Common - flagellin CCV52592_0745 94 COG1981 COG1981, Predicted membrane protein Function unknown 154174963 Common nikD nickel transport permease component NikD CCV52592_0726 171 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 154174827 Common - TonB-dependent siderophore receptor CCV52592_0607 119 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 154175316 Common - putative branched-chain amino acid transport protein CCV52592_0750 46 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 154175046 Common - hypothetical protein CCV52592_0532 4 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 154175439 Common rplC ribosomal protein L3 CCV52592_1032 217 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 154173877 Common rfaF lipopolysaccharide heptosyltransferase II CCV52592_1237 102 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 154174541 Common - Sel1 repeat family CCV52592_0250 88 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 154174525 Pathogen - hypothetical protein CCV52592_0133 1 None None None 154174232 Pathogen - hypothetical protein CCV52592_2015 1 None None None 154175500 Common fixO cytochrome c oxidase, monoheme subunit, membrane-bound CCV52592_1408 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 154173692 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase CCV52592_0515 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 154173697 Common thiD phosphomethylpyrimidine kinase CCV52592_0496 216 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 154175192 Common - thymidylate kinase (dTMP kinase) CCV52592_1903 78 COG1740 HyaA, Ni,Fe-hydrogenase I small subunit Energy production and conversion 154174419 Common - immunogenic protein CCV52592_0082 83 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 154175358 Common - sulfate/thiosulfate import ATP-binding protein CysA 2 (Sulfate-transporting ATPase 2) CCV52592_1977 112 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 154173744 Common - competence/damage-inducible domain protein CCV52592_0975 193 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 154174584 Common fliN flagellar motor switch protein FliN CCV52592_1689 119 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 154175153 Common - hypothetical protein CCV52592_2090 5 None None None 154173645 Common - putative thiamine-phosphate pyrophosphorylase CCV52592_1869 30 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 154173944 Common - disulfide isomerase CCV52592_0856 31 None None None 154175446 Common - PilT CCV52592_1145 87 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154174033 Pathogen - hypothetical protein CCV52592_2021 1 None None None 154173800 Common - hypothetical protein CCV52592_0121 76 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 154173930 Pathogen - hypothetical protein CCV52592_0567 1 None None None 154173727 Common groS chaperonin GroS CCV52592_0309 214 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 154175263 Common ilvD dihydroxy-acid dehydratase CCV52592_2036 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 154175434 Common - lipoprotein CCV52592_0360 13 COG3779 COG3779, Uncharacterized protein conserved in bacteria Function unknown 154174306 Pathogen - hypothetical protein CCV52592_0035 1 COG3926 zliS, Putative secretion activating protein General function prediction only 154174488 Common - type I restriction-modification system, R subunit CCV52592_1475 141 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 154174496 Common - thiamine-phosphate pyrophosphorylase CCV52592_2114 20 None None None 154174151 Common - thiamine biosynthesis protein:ExsB CCV52592_2075 42 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 154173940 Pathogen - hypothetical protein CCV52592_2038 1 None None None 154174362 Common - mercuric transport protein periplasmic component CCV52592_0117 39 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 154175369 Pathogen - hypothetical protein CCV52592_2217 1 None None None 154174967 Common - membrane-fusion protein CCV52592_1253 117 COG2855 COG2855, Predicted membrane protein Function unknown 154175182 Common - diguanylate cyclase/phosphodiesterase CCV52592_0404 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 154174880 Common - hypothetical protein CCV52592_1638 2 None None None 154174138 Common - ribonuclease R CCV52592_1583 192 COG0557 VacB, Exoribonuclease R Transcription 154174166 Pathogen - hypothetical protein CCV52592_0986 1 None None None 154174569 Common - cupin 2, conserved barrel domain protein CCV52592_0944 36 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 154174220 Common - glycosyl hyrolase, family 3 CCV52592_0793 181 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 154175171 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 family protein CCV52592_1595 4 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 154175528 Common - hypothetical protein CCV52592_0014 18 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 154175485 Common - CTA2 subfamily 1 protein 7 CCV52592_0283 20 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 154174377 Common gidB methyltransferase GidB CCV52592_1345 137 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 154175470 Common - UDP-N-acetylmuramate--L-alanine ligase (UDP-N-acetylmuramoyl-L-alanine synthetase) CCV52592_0395 124 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 154174349 Common - protein YegH CCV52592_1505 116 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 154174538 Pathogen - hypothetical protein CCV52592_2088 1 None None None 154173675 Common aroK shikimate kinase CCV52592_1187 198 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 154174548 Common gatC glutamyl-tRNA(Gln) amidotransferase, C subunit CCV52592_0997 49 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 154175477 Common - molybdenum-pterin binding protein CCV52592_1617 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 154175517 Pathogen - hypothetical protein CCV52592_2233 1 None None None 154175281 Pathogen - hypothetical protein CCV52592_1629 1 None None None 154174439 Common - aspartate racemase CCV52592_1034 78 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 154175135 Common - ATPase, AAA family protein CCV52592_1997 149 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 154174976 Common hemA glutamyl-tRNA reductase CCV52592_0764 180 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 154175233 Common purM phosphoribosylformylglycinamidine cyclo-ligase CCV52592_0351 229 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 154174461 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase CCV52592_0618 141 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 154175079 Common - putative conserved hypothetical protein CCV52592_0914 168 COG0546 Gph, Predicted phosphatases General function prediction only 154174778 Common - SCO1/SenC family protein CCV52592_1941 97 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 154174510 Common - glycerate kinase 1 CCV52592_0612 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 154175189 Common - transcriptional regulator, ArsR family CCV52592_2122 72 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 154175034 Common nfo endonuclease IV CCV52592_0162 100 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 154174012 Common - ATP synthase subunit B CCV52592_1733 9 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 154174519 Common tsf translation elongation factor Ts CCV52592_1261 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 154174531 Common - 4Fe-4S ferredoxin, iron-sulfur binding CCV52592_1932 31 COG2221 DsrA, Dissimilatory sulfite reductase (desulfoviridin), alpha and beta subunits Energy production and conversion 154175405 Common - amino acid carrier family protein CCV52592_1998 37 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 154173859 Common - hypothetical protein CCV52592_1178 7 None None None 154173705 Common - hypothetical protein CCV52592_2195 1 None None None 154174661 Common ccoP cytochrome c oxidase, Cbb3-type, subunit III CCV52592_0905 77 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 154174936 Common - putative periplasmic protein CCV52592_0613 2 None None None 154174941 Common - ankyrin repeat protein CCV52592_1417 38 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 154174741 Common - hypothetical protein CCV52592_0783 6 None None None 154174767 Common - hypothetical protein CCV52592_1701 7 None None None 154173846 Common - putative probable oxidoreductase CCV52592_1802 37 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 154173852 Common hemB delta-aminolevulinic acid dehydratase CCV52592_1348 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 154173620 Common - glycosyl transferase, group 1 family protein CCV52592_1214 196 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 154174862 Common proC pyrroline-5-carboxylate reductase CCV52592_0752 211 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 154174637 Common - zinc metalloprotease CCV52592_0079 136 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 154174899 Common trpB tryptophan synthase, beta subunit CCV52592_1686 228 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 154173815 Common - hypothetical protein CCV52592_1849 3 None None None 154174370 Common - branched-chain amino acid transport protein CCV52592_0102 102 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 154173883 Common - putative pyruvate kinase CCV52592_0353 24 COG4922 COG4922, Uncharacterized protein conserved in bacteria Function unknown 154174127 Common hgpB hemoglobin and hemoglobin-haptoglobin binding protein B CCV52592_0590 58 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 154175535 Pathogen - hypothetical protein CCV52592_1772 1 None None None 154175000 Pathogen - GatB/Yqey family protein CCV52592_0038 1 None None None 154174203 Common - putative two-component sensor CCV52592_1918 209 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 154174565 Common - NADH-quinone oxidoreductase subunit i (nadhdehydrogenase i subunit i) (ndh-1 subunit i) CCV52592_1521 185 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 154174728 Common - protein YhbP CCV52592_1054 18 COG3787 COG3787, Uncharacterized protein conserved in bacteria Function unknown 154174090 Common - hypothetical protein CCV52592_1822 1 None None None 154175141 Common mfd transcription-repair coupling factor CCV52592_0714 223 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 154174875 Common - radical SAM domain protein CCV52592_1538 203 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 154175334 Common purU formyltetrahydrofolate deformylase CCV52592_1370 220 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 154174358 Pathogen - hypothetical protein CCV52592_0215 1 None None None 154174226 Pathogen - hypothetical protein CCV52592_1042 1 None None None 154175288 Pathogen - glycosyl transferase, group 2 family protein CCV52592_0382 1 None None None 154174466 Common lspA signal peptidase II CCV52592_0743 94 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 154174024 Common - radical SAM domain protein CCV52592_2061 42 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 154175030 Common fliR flagellar biosynthetic protein FliR CCV52592_1258 128 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 154174578 Common - quinone-reactive Ni/Fe-hydrogenase large chain CCV52592_1902 98 COG0374 HyaB, Ni,Fe-hydrogenase I large subunit Energy production and conversion 154175088 Pathogen - hypothetical protein CCV52592_0134 1 None None None 154174049 Common - hypothetical protein CCV52592_0091 35 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 154174399 Pathogen - hypothetical protein CCV52592_1055 1 None None None 154175325 Common acpP acyl carrier protein CCV52592_1083 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 154174834 Common murG undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase CCV52592_1988 207 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 154174097 Pathogen - hypothetical protein CCV52592_2089 1 None None None 154173753 Common - NADH oxidase CCV52592_1244 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 154174815 Common atpA ATP synthase F1, alpha subunit CCV52592_1736 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 154174211 Common - hypothetical protein CCV52592_0018 11 COG3926 zliS, Putative secretion activating protein General function prediction only 154173834 Pathogen - hypothetical protein CCV52592_1679 1 None None None 154174898 Common - NADH-quinone oxidoreductase chain m (NADH dehydrogenase i, chain m) (ndh-1, chain m) CCV52592_1517 209 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 154175214 Pathogen - hypothetical protein CCV52592_2128 1 None None None 154174040 Common - hypothetical protein CCV52592_2051 3 None None None 154174432 Pathogen - hypothetical protein CCV52592_1796 1 None None None 154174457 Common - polyribonucleotide nucleotidyltransferase (Polynucleotidephosphorylase) (PNPase) CCV52592_0953 234 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 154173897 Common - putative flavocytochrome c flavin subunit CCV52592_1545 124 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 154175396 Common fabZ beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ CCV52592_0865 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 154174861 Pathogen - hypothetical protein CCV52592_0061 1 None None None 154174559 Common - outer membrane receptor for fe CCV52592_2000 92 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 154174182 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase CCV52592_1671 215 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 154174133 Common - putative high-molecular-weight surface-exposed protein CCV52592_1393 2 None None None 154173981 Common - disulfide bond formation protein B CCV52592_1146 27 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 154174874 Common - biopolymer transport ExbB protein CCV52592_1050 145 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 154174241 Common - lipopolysaccharide core biosynthesis glycosyltransferase KdtX CCV52592_1230 119 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 154174849 Common - putative BcpB CCV52592_0580 13 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 154175344 Common hcp hydroxylamine reductase CCV52592_0447 74 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion