Ochrobactrum anthropi ATCC 49188 chromosome 2, complete sequence NC_009668 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 153010654 Common - protein of unknown function DUF395 YeeE/YedE Oant_3333 62 COG2391 COG2391, Predicted transporter component General function prediction only 153010206 Common - alpha/beta hydrolase fold Oant_2883 76 COG2267 PldB, Lysophospholipase Lipid metabolism 153010190 Common - L-seryl-tRNA(Sec) selenium transferase Oant_2867 73 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 153011326 Common - Acyl-CoA dehydrogenase type 2 domain protein Oant_4006 37 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153010715 Common - major facilitator superfamily MFS_1 Oant_3394 138 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153011426 Common - PTS system protein II sorbitol-specific factor Oant_4109 22 COG3730 SrlA, Phosphotransferase system sorbitol-specific component IIC Carbohydrate transport and metabolism 153011405 Common - TonB-dependent receptor Oant_4087 95 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 153010633 Common - protein of unknown function UPF0029 Oant_3312 134 COG1739 COG1739, Uncharacterized conserved protein Function unknown 153011707 Common - putative dioxygenase Oant_4392 5 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153010466 Common - hypothetical protein Oant_3143 4 None None None 153010369 Common - Three-deoxy-D-manno-octulosonic-acid transferase domain protein Oant_3046 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 153011317 Common - Cupin 2 conserved barrel domain protein Oant_3997 11 COG3837 COG3837, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 153010338 Common - DNA-3-methyladenine glycosylase I Oant_3015 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 153011077 Common - short-chain dehydrogenase/reductase SDR Oant_3756 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153011738 Common - inner-membrane translocator Oant_4423 146 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 153011410 Common - TRAP dicarboxylate transporter, DctM subunit Oant_4093 132 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 153011068 Common - polar amino acid ABC transporter, inner membrane subunit Oant_3747 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153010663 Common - SMP-30/Gluconolaconase/LRE domain protein Oant_3342 67 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 153010730 Common - Xylose isomerase domain protein TIM barrel Oant_3409 56 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 153010300 Common - binding-protein-dependent transport systems inner membrane component Oant_2977 131 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153011751 Common - hypothetical protein Oant_4436 13 COG3383 COG3383, Uncharacterized anaerobic dehydrogenase General function prediction only 153011747 Common - protein of unknown function DUF922 Oant_4432 9 COG5664 COG5664, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 153010719 Common - putative transmembrane anti-sigma factor Oant_3398 25 COG5662 COG5662, Predicted transmembrane transcriptional regulator (anti-sigma factor) Transcription 153010189 Common - formate dehydrogenase accessory protein FdhE Oant_2866 39 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 153011108 Common - extracellular solute-binding protein family 5 Oant_3787 207 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153011638 Common - hypothetical protein Oant_4323 3 None None None 153010140 Common - FGGY-family pentulose kinase Oant_2816 177 COG1069 AraB, Ribulose kinase Energy production and conversion 153010270 Common - iron-containing alcohol dehydrogenase Oant_2947 172 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 153011417 Common - TRAP transporter, 4TM/12TM fusion protein Oant_4100 123 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 153011595 Pathogen - hypothetical protein Oant_4280 2 None None None 153010707 Common - hypothetical protein Oant_3386 12 None None None 153010678 Common - short-chain dehydrogenase/reductase SDR Oant_3357 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153011602 Common - hypothetical protein Oant_4287 12 None None None 153011039 Common - beta-ketoadipyl CoA thiolase Oant_3718 171 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 153011470 Common - spermidine/putrescine ABC transporter ATPase subunit Oant_4155 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153011700 Pathogen - NorF protein Oant_4385 2 None None None 153010341 Common - tRNA synthetase class II (G H P and S) Oant_3018 172 COG3705 HisZ, ATP phosphoribosyltransferase involved in histidine biosynthesis Amino acid transport and metabolism 153010251 Common - major facilitator superfamily MFS_1 Oant_2928 199 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010460 Common - Protein of unknown function DUF1778 Oant_3137 12 COG4453 COG4453, Uncharacterized protein conserved in bacteria Function unknown 153011362 Common - putative mRNA 3-end processing factor Oant_4043 77 COG1236 YSH1, Predicted exonuclease of the beta-lactamase fold involved in RNA processing Translation, ribosomal structure and biogenesis 153010419 Common - transcriptional regulator, GntR family Oant_3096 143 COG1802 GntR, Transcriptional regulators Transcription 153011631 Common - Ku family containing protein Oant_4316 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 153010693 Common - GDP-mannose 4,6-dehydratase Oant_3372 219 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 153010869 Common - binding-protein-dependent transport systems inner membrane component Oant_3548 171 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153010797 Common - ABC transporter related Oant_3476 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 153011101 Common - two component transcriptional regulator, winged helix family Oant_3780 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153010647 Common - Uncharacterized protein UPF0114 Oant_3326 56 COG2862 COG2862, Predicted membrane protein Function unknown 153010315 Common - putative transmembrane protein Oant_2992 8 None None None 153010374 Common - Chloride channel core Oant_3051 159 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 153010402 Common - carbohydrate kinase FGGY Oant_3079 169 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 153010488 Common - hypothetical protein Oant_3165 7 None None None 153011061 Common - binding-protein-dependent transport systems inner membrane component Oant_3740 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011003 Pathogen - hypothetical protein Oant_3682 1 None None None 153010373 Common - peptidase S58 DmpA Oant_3050 51 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153010115 Common - binding-protein-dependent transport systems inner membrane component Oant_2791 169 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153010862 Common - cytochrome bd ubiquinol oxidase subunit I Oant_3541 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 153010476 Common - hypothetical protein Oant_3153 9 None None None 153010853 Common - NADH-ubiquinone oxidoreductase chain 4L Oant_3532 100 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 153011021 Common - ABC-3 protein Oant_3700 184 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 153011084 Common - Tripartite ATP-independent periplasmic transporter DctQ component Oant_3763 58 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 153010083 Common - helix-turn-helix- domain containing protein AraC type Oant_2758 50 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153011338 Common - Endoribonuclease L-PSP Oant_4018 106 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153011344 Common - extracellular solute-binding protein family 3 Oant_4024 175 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153011760 Common - ADP-ribosylation/Crystallin J1 Oant_4445 12 COG1397 DraG, ADP-ribosylglycohydrolase Posttranslational modification, protein turnover, chaperones 153010382 Common - hypothetical protein Oant_3059 7 None None None 153010772 Common - outer membrane autotransporter barrel domain protein Oant_3451 28 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 153011286 Common - binding-protein-dependent transport systems inner membrane component Oant_3966 218 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011034 Common - putative transcriptional regulator, AsnC family Oant_3713 143 COG1522 Lrp, Transcriptional regulators Transcription 153010751 Common - hypothetical protein Oant_3430 9 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 153010307 Common - extracellular solute-binding protein family 5 Oant_2984 191 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153010213 Common - nitrite transporter Oant_2890 98 COG2223 NarK, Nitrate/nitrite transporter Inorganic ion transport and metabolism 153011460 Common - transcriptional regulator, GntR family Oant_4145 139 COG2188 PhnF, Transcriptional regulators Transcription 153010528 Common - electron transport protein SCO1/SenC Oant_3205 104 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 153011768 Pathogen - hypothetical protein Oant_4453 1 None None None 153011442 Common - protein of unknown function DUF336 Oant_4125 13 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 153011253 Common - protein of unknown function UPF0187 Oant_3933 56 COG3781 COG3781, Predicted membrane protein Function unknown 153011117 Common - putative esterase Oant_3796 44 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 153010596 Common - hypothetical protein Oant_3273 4 COG5428 COG5428, Uncharacterized conserved small protein Function unknown 153011723 Common - glutathione-dependent formaldehyde-activating GFA Oant_4408 47 COG3791 COG3791, Uncharacterized conserved protein Function unknown 153010979 Pathogen - hypothetical protein Oant_3658 2 None None None 153010776 Common - binding-protein-dependent transport systems inner membrane component Oant_3455 147 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153010244 Common - transcriptional regulator, AraC family Oant_2921 149 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 153010333 Common - D-lactate dehydrogenase (cytochrome) Oant_3010 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 153011746 Common - Tripartite ATP-independent periplasmic transporter DctQ component Oant_4431 57 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 153010960 Common - DSBA oxidoreductase Oant_3639 89 COG2761 FrnE, Predicted dithiol-disulfide isomerase involved in polyketide biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 153010671 Pathogen - hypothetical protein Oant_3350 4 None None None 153011625 Common - isochorismatase hydrolase Oant_4310 24 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 153011070 Common - periplasmic binding protein/LacI transcriptional regulator Oant_3749 125 COG1609 PurR, Transcriptional regulators Transcription 153010258 Common - short-chain dehydrogenase/reductase SDR Oant_2935 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153010722 Common - GntR domain protein Oant_3401 124 COG2186 FadR, Transcriptional regulators Transcription 153010204 Pathogen - hypothetical protein Oant_2881 1 None None None 153010615 Common - dihydrodipicolinate synthetase Oant_3294 159 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 153011224 Common - Galactarate dehydratase Oant_3904 73 COG2721 UxaA, Altronate dehydratase Carbohydrate transport and metabolism 153010810 Common - Homoserine O-succinyltransferase Oant_3489 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 153011395 Common - hypothetical protein Oant_4077 14 None None None 153011598 Common - N-formylglutamate amidohydrolase Oant_4283 57 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 153010495 Common - prevent-host-death family protein Oant_3172 6 COG4118 Phd, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 153010229 Common - Triose-phosphate isomerase Oant_2906 217 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 153010451 Common - binding-protein-dependent transport systems inner membrane component Oant_3128 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010907 Common - protein of unknown function DUF6 transmembrane Oant_3586 137 COG2962 RarD, Predicted permeases General function prediction only 153010325 Common - protein of unknown function DUF1656 Oant_3002 12 None None None 153010490 Common - nuclease (SNase domain protein) Oant_3167 49 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 153010122 Common - transcriptional regulator, GntR family Oant_2798 91 COG1802 GntR, Transcriptional regulators Transcription 153010557 Common - cation diffusion facilitator family transporter Oant_3234 191 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 153011099 Common - potassium-transporting ATPase, C subunit Oant_3778 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 153011241 Common - MgtC/SapB transporter Oant_3921 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 153011357 Pathogen - hypothetical protein Oant_4038 1 None None None 153010458 Common - Recombinase Oant_3135 85 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 153010126 Common - extracellular solute-binding protein family 1 Oant_2802 123 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 153011582 Common - band 7 protein Oant_4267 217 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 153010391 Common - GntR domain protein Oant_3068 137 COG2186 FadR, Transcriptional regulators Transcription 153010570 Common - cytochrome c biogenesis protein transmembrane region Oant_3247 119 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 153010186 Common - formate dehydrogenase, alpha subunit Oant_2863 178 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 153010388 Common - hypothetical protein Oant_3065 11 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 153010157 Common - ABC transporter related Oant_2834 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153011758 Common - inner-membrane translocator Oant_4443 105 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 153010545 Common - hypothetical protein Oant_3222 23 COG5639 COG5639, Uncharacterized conserved small protein Function unknown 153011390 Common - dihydroxyacetone kinase, L subunit Oant_4072 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 153010280 Common - 4-phytase Oant_2957 216 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153011547 Common - spermidine/putrescine ABC transporter ATPase subunit Oant_4232 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153011050 Common - 3-carboxy-cis,cis-muconate cycloisomerase Oant_3729 113 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 153011676 Common - hypothetical protein Oant_4361 47 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 153011641 Common - transposase IS3/IS911 family protein Oant_4326 21 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 153010695 Common - glycosyl transferase group 1 Oant_3374 169 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153010769 Common - short-chain dehydrogenase/reductase SDR Oant_3448 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153011057 Common - beta-lactamase Oant_3736 59 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 153010579 Common - hypothetical protein Oant_3256 40 None None None 153011247 Common - spermidine/putrescine ABC transporter ATPase subunit Oant_3927 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153010100 Common - TonB-dependent siderophore receptor Oant_2776 124 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 153010905 Common - transcriptional regulator, BadM/Rrf2 family Oant_3584 59 COG1959 COG1959, Predicted transcriptional regulator Transcription 153010107 Common - binding-protein-dependent transport systems inner membrane component Oant_2783 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011197 Common - N-formylglutamate amidohydrolase Oant_3877 42 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 153011710 Common - Extracellular ligand-binding receptor Oant_4395 122 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 153010604 Common - YbaK/prolyl-tRNA synthetase associated region Oant_3283 31 COG3760 COG3760, Uncharacterized conserved protein Function unknown 153010227 Common - fructose-bisphosphate aldolase, class II, Calvin cycle subtype Oant_2904 163 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 153011195 Common - transcriptional regulator, TetR family Oant_3875 55 COG1309 AcrR, Transcriptional regulator Transcription 153011545 Common - binding-protein-dependent transport systems inner membrane component Oant_4230 148 COG4132 COG4132, ABC-type uncharacterized transport system, permease component General function prediction only 153010741 Common - hypothetical protein Oant_3420 4 None None None 153011612 Common - prolyl oligopeptidase family protein Oant_4297 7 COG1647 COG1647, Esterase/lipase General function prediction only 153011049 Common - protocatechuate 3,4-dioxygenase, alpha subunit Oant_3728 40 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 153010885 Common - major facilitator superfamily MFS_1 Oant_3564 196 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010889 Common - Monosaccharide-transporting ATPase Oant_3568 124 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153010942 Common - Haemin-degrading family protein Oant_3621 40 COG3720 HemS, Putative heme degradation protein Inorganic ion transport and metabolism 153010512 Common - conjugal transfer protein precursor Oant_3189 30 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153011648 Common - hypothetical protein Oant_4333 12 None None None 153010102 Common - transport system permease protein Oant_2778 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153011517 Pathogen - hypothetical protein Oant_4202 1 None None None 153010973 Common - signal transduction histidine kinase Oant_3652 133 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 153011276 Common - glucose-6-phosphate 1-dehydrogenase Oant_3956 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 153010989 Common - protein of unknown function DUF205 Oant_3668 170 COG0344 COG0344, Predicted membrane protein Function unknown 153011120 Common - transport system permease protein Oant_3799 111 COG4605 CeuC, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 153011717 Common - 3-hydroxyanthranilate 3,4-dioxygenase Oant_4402 16 COG1791 COG1791, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 153010287 Common - UbiA prenyltransferase Oant_2964 50 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 153010521 Common - arsenical-resistance protein Oant_3198 135 COG0798 ACR3, Arsenite efflux pump ACR3 and related permeases Inorganic ion transport and metabolism 153010172 Common - polar amino acid ABC transporter, inner membrane subunit Oant_2849 178 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153011209 Common - glycine betaine/L-proline ABC transporter, ATPase subunit Oant_3889 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 153011586 Common - gluconate transporter Oant_4271 79 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 153011062 Common - extracellular solute-binding protein family 5 Oant_3741 187 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153011561 Common - Amidase Oant_4246 220 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 153010744 Common - Uncharacterized protein UPF0065 Oant_3423 65 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 153011488 Common - transcriptional regulator, BadM/Rrf2 family Oant_4173 172 COG1959 COG1959, Predicted transcriptional regulator Transcription 153010939 Common - ABC transporter related Oant_3618 249 COG4559 COG4559, ABC-type hemin transport system, ATPase component Inorganic ion transport and metabolism 153011656 Common - ApbE family lipoprotein Oant_4341 112 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 153010875 Common - dihydrolipoamide dehydrogenase Oant_3554 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 153011186 Common - major facilitator superfamily MFS_1 Oant_3866 120 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010263 Common - extracellular solute-binding protein family 1 Oant_2940 108 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010980 Common - GCN5-related N-acetyltransferase Oant_3659 11 COG0456 RimI, Acetyltransferases General function prediction only 153010436 Common - two component, sigma54 specific, transcriptional regulator, Fis family Oant_3113 221 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 153010417 Common - MmgE/PrpD family protein Oant_3094 54 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 153011658 Common - NosY, nitrous-oxide reductase, NosY component Oant_4343 71 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 153011697 Common - Hemerythrin HHE cation binding domain protein Oant_4382 5 None None None 153011172 Common - binding-protein-dependent transport systems inner membrane component Oant_3852 144 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153011524 Common - flagellar basal-body rod protein FlgG Oant_4209 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 153010275 Common - glutaredoxin-like protein NrdH Oant_2952 39 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 153011179 Common - iron permease FTR1 Oant_3859 98 COG0672 FTR1, High-affinity Fe2+/Pb2+ permease Inorganic ion transport and metabolism 153010543 Common - P-type conjugative transfer protein TrbG Oant_3220 51 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 153010916 Common - alpha/beta hydrolase fold Oant_3595 125 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153011627 Common - porin Oant_4312 34 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 153011506 Common - flagellar hook-associated 3 family protein Oant_4191 17 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 153011603 Pathogen - hypothetical protein Oant_4288 1 None None None 153011661 Common - Nitrous-oxide reductase Oant_4346 41 COG4263 NosZ, Nitrous oxide reductase Energy production and conversion 153011216 Common - binding-protein-dependent transport systems inner membrane component Oant_3896 175 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153011698 Common - hypothetical protein Oant_4383 4 None None None 153010426 Common - hypothetical protein Oant_3103 6 None None None 153010168 Common - transcriptional regulator, TetR family Oant_2845 52 COG1309 AcrR, Transcriptional regulator Transcription 153011223 Common - Alcohol dehydrogenase zinc-binding domain protein Oant_3903 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 153011706 Common - Alpha/beta hydrolase fold-3 domain protein Oant_4391 69 COG0657 Aes, Esterase/lipase Lipid metabolism 153010163 Common - Monosaccharide-transporting ATPase Oant_2840 136 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153010966 Common - cytochrome c biogenesis protein transmembrane region Oant_3645 135 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 153011296 Common - hypothetical protein Oant_3976 3 None None None 153011378 Common - PfkB domain protein Oant_4060 173 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153010211 Common - hypothetical protein Oant_2888 29 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 153010113 Common - spermidine/putrescine ABC transporter ATPase subunit Oant_2789 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153010197 Common - integral membrane sensor signal transduction histidine kinase Oant_2874 219 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 153010537 Common - conjugal transfer protein TrbB Oant_3214 25 COG5268 TrbD, Type IV secretory pathway, TrbD component Cell motility and secretion / Intracellular trafficking and secretion 153011333 Common - Indolepyruvate ferredoxin oxidoreductase Oant_4013 92 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 153010137 Common - ABC transporter related Oant_2813 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153011182 Common - glycine dehydrogenase Oant_3862 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 153010895 Common - 2OG-Fe(II) oxygenase Oant_3574 56 COG3145 AlkB, Alkylated DNA repair protein DNA replication, recombination, and repair 153010371 Common - hypothetical protein Oant_3048 23 COG3908 COG3908, Uncharacterized protein conserved in bacteria Function unknown 153011349 Common - putative phage repressor Oant_4030 30 COG2932 COG2932, Predicted transcriptional regulator Transcription 153010565 Common - protein of unknown function DUF305 Oant_3242 51 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 153011553 Common - glycosyl transferase family 2 Oant_4238 22 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 153011510 Common - Lytic transglycosylase catalytic Oant_4195 43 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 153010785 Common - Ectoine/hydroxyectoine ABC transporter permease protein EhuC Oant_3464 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153010645 Common - Substrate-binding region of ABC-type glycine betaine transport system Oant_3324 62 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 153010548 Common - regulatory protein ArsR Oant_3225 58 COG0640 ArsR, Predicted transcriptional regulators Transcription 153011016 Common - hypothetical protein Oant_3695 3 None None None 153010834 Common - ABC transporter related Oant_3513 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 153010421 Common - Uncharacterized protein UPF0065 Oant_3098 75 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 153010891 Common - rhamnose ABC transporter, periplasmic rhamnose-binding protein Oant_3570 93 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153011535 Common - flagellar motor switch protein FliN Oant_4220 123 COG1886 FliN, Flagellar motor switch/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 153010507 Common - replication protein A Oant_3184 32 COG5534 COG5534, Plasmid replication initiator protein DNA replication, recombination, and repair 153010585 Common - NADH:flavin oxidoreductase/NADH oxidase Oant_3262 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 153011450 Common - TonB-dependent siderophore receptor Oant_4135 104 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 153011684 Common - Monosaccharide-transporting ATPase Oant_4369 114 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153011466 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Oant_4151 204 COG0388 COG0388, Predicted amidohydrolase General function prediction only 153011127 Common - putative transcriptional regulator Oant_3806 24 COG5631 COG5631, Predicted transcription regulator, contains HTH domain (MarR family) Transcription 153011235 Common - transport system permease protein Oant_3915 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153011633 Pathogen - hypothetical protein Oant_4318 1 None None None 153011454 Common - putative transcriptional regulator, GntR family Oant_4139 214 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153011702 Common - Nitric-oxide reductase Oant_4387 105 COG3256 NorB, Nitric oxide reductase large subunit Inorganic ion transport and metabolism 153010117 Common - YD repeat protein Oant_2793 36 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 153010821 Common - peptidase M20 Oant_3500 26 COG4187 RocB, Arginine degradation protein (predicted deacylase) Amino acid transport and metabolism 153011614 Common - hypothetical protein Oant_4299 10 None None None 153010674 Common - Amidohydrolase 3 Oant_3353 114 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 153010178 Common - GCN5-related N-acetyltransferase Oant_2855 88 COG0456 RimI, Acetyltransferases General function prediction only 153011119 Common - transport system permease protein Oant_3798 191 COG4606 CeuB, ABC-type enterochelin transport system, permease component Inorganic ion transport and metabolism 153010381 Common - GMP synthase, large subunit Oant_3058 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 153010990 Common - DNA protecting protein DprA Oant_3669 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 153011386 Common - short-chain dehydrogenase/reductase SDR Oant_4068 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153010664 Common - Dihydroxy-acid dehydratase Oant_3343 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 153010808 Common - ROK family protein Oant_3487 106 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 153010699 Common - protein of unknown function DUF218 Oant_3378 29 COG1434 COG1434, Uncharacterized conserved protein Function unknown 153010478 Common - hypothetical protein Oant_3155 2 None None None 153011412 Common - mannonate dehydratase Oant_4095 57 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 153011609 Common - hypothetical protein Oant_4294 16 None None None 153011526 Common - flagellar basal-body rod protein FlgC Oant_4211 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 153010360 Common - putative methyltransferase Oant_3037 213 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 153010467 Common - protein of unknown function DUF159 Oant_3144 30 COG2135 COG2135, Uncharacterized conserved protein Function unknown 153010398 Common - transcriptional regulator, DeoR family Oant_3075 68 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 153010085 Common - Inosine/uridine-preferring nucleoside hydrolase Oant_2761 84 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 153010610 Common - major facilitator superfamily MFS_1 Oant_3289 119 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 153010087 Common - extracellular solute-binding protein family 3 Oant_2763 172 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153010264 Common - binding-protein-dependent transport systems inner membrane component Oant_2941 180 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153010159 Common - aldehyde dehydrogenase Oant_2836 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153011539 Common - regulatory protein LuxR Oant_4224 66 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 153010132 Common - ABC transporter related Oant_2808 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153010767 Common - penicillin-binding protein 1C Oant_3446 200 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 153011424 Common - hypothetical protein Oant_4107 3 None None None 153011530 Common - flagellar basal body rod protein Oant_4215 123 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 153011681 Common - transcriptional regulator, LysR family Oant_4366 156 COG0583 LysR, Transcriptional regulator Transcription 153010729 Common - ribose ABC transporter, periplasmic D-ribose-binding protein Oant_3408 96 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153011688 Common - regulatory protein LacI Oant_4373 126 COG1609 PurR, Transcriptional regulators Transcription 153010955 Common - Phosphatidylcholine synthase Oant_3634 28 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 153010635 Common - amidohydrolase Oant_3314 169 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 153010272 Common - flavin reductase domain protein FMN-binding Oant_2949 102 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 153010685 Common - methionine-R-sulfoxide reductase Oant_3364 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 153011009 Pathogen - hypothetical protein Oant_3688 1 None None None 153011593 Common - Threonine aldolase Oant_4278 99 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 153011054 Common - ABC transporter related Oant_3733 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153010284 Common - GntR domain protein Oant_2961 126 COG2186 FadR, Transcriptional regulators Transcription 153010552 Common - transmembrane protein Oant_3229 96 COG1238 COG1238, Predicted membrane protein Function unknown 153011749 Common - FAD dependent oxidoreductase Oant_4434 113 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153010470 Common - DNA polymerase III, alpha subunit Oant_3147 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 153010713 Common - LmbE family protein Oant_3392 19 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 153011315 Common - helix-turn-helix- domain containing protein AraC type Oant_3995 57 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 153010717 Common - Secreted repeat-containing protein Oant_3396 37 COG4315 COG4315, Uncharacterized protein conserved in bacteria Function unknown 153010863 Common - cytochrome d ubiquinol oxidase, subunit II Oant_3542 156 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 153010256 Common - RES domain protein Oant_2933 26 None None None 153011146 Common - ABC transporter related Oant_3825 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153011402 Common - periplasmic binding protein Oant_4084 48 COG4592 FepB, ABC-type Fe2+-enterobactin transport system, periplasmic component Inorganic ion transport and metabolism 153010095 Common - binding-protein-dependent transport systems inner membrane component Oant_2771 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010146 Common - 8-amino-7-oxononanoate synthase Oant_2822 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 153011301 Common - hypothetical protein Oant_3981 25 COG5477 COG5477, Predicted small integral membrane protein Function unknown 153011403 Common - ABC transporter related Oant_4085 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 153010588 Common - extracellular solute-binding protein family 3 Oant_3265 167 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153010576 Pathogen - hypothetical protein Oant_3253 1 None None None 153010841 Common - polar amino acid ABC transporter, inner membrane subunit Oant_3520 172 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 153010294 Common - septum site-determining protein MinD Oant_2971 140 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 153011014 Common - peptidase U35 phage prohead HK97 Oant_3693 21 None None None 153011047 Common - 4-carboxymuconolactone decarboxylase Oant_3726 87 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 153011564 Common - high-affinity nickel-transporter Oant_4249 40 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 153011163 Common - Inositol-phosphate phosphatase Oant_3842 203 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 153010492 Common - hypothetical protein Oant_3169 9 None None None 153011397 Common - putative transcriptional regulator, AsnC family Oant_4079 131 COG1522 Lrp, Transcriptional regulators Transcription 153010184 Common - transglutaminase domain protein Oant_2861 31 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 153011549 Common - MOSC domain containing protein Oant_4234 39 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 153010393 Common - protein of unknown function DUF336 Oant_3070 83 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 153010497 Common - probably methylase/helicase Oant_3174 22 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 153010456 Common - diguanylate cyclase/phosphodiesterase Oant_3133 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 153011351 Common - acetyl-CoA acetyltransferase Oant_4032 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 153011265 Common - putative transcriptional regulator, AsnC family Oant_3945 165 COG1522 Lrp, Transcriptional regulators Transcription 153011459 Common - protein of unknown function DUF81 Oant_4144 132 COG0730 COG0730, Predicted permeases General function prediction only 153011273 Common - major facilitator superfamily MFS_1 Oant_3953 173 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153011093 Common - protein of unknown function DUF6 transmembrane Oant_3772 81 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 153010524 Common - regulatory protein ArsR Oant_3201 67 COG0640 ArsR, Predicted transcriptional regulators Transcription 153010120 Common - Ectoine synthase Oant_2796 35 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 153010641 Common - extracellular solute-binding protein family 5 Oant_3320 209 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153010386 Common - hypothetical protein Oant_3063 11 COG5618 COG5618, Predicted periplasmic lipoprotein General function prediction only 153011484 Common - Transglycosylase-associated protein Oant_4169 18 COG2261 COG2261, Predicted membrane protein Function unknown 153011495 Pathogen - type IV pilus assembly PilZ Oant_4180 2 None None None 153010405 Pathogen - hypothetical protein Oant_3082 1 None None None 153010656 Common - transcriptional regulator, GntR family Oant_3335 140 COG1802 GntR, Transcriptional regulators Transcription 153010331 Pathogen - hypothetical protein Oant_3008 2 None None None 153010150 Common - transport system permease protein Oant_2826 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153010774 Common - Formaldehyde dehydrogenase glutathione-independent Oant_3453 174 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 153010462 Common - nuclease (SNase-like) Oant_3139 8 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 153010379 Common - thioesterase superfamily protein Oant_3056 67 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 153011251 Common - hypothetical protein Oant_3931 6 None None None 153011336 Common - Enoyl-CoA hydratase/isomerase Oant_4016 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 153010503 Common - hypothetical protein Oant_3180 13 None None None 153011257 Common - FAD dependent oxidoreductase Oant_3937 125 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153010243 Common - Substrate-binding region of ABC-type glycine betaine transport system Oant_2920 73 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 153011066 Common - ABC transporter related Oant_3745 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153010309 Common - binding-protein-dependent transport systems inner membrane component Oant_2986 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011036 Common - binding-protein-dependent transport systems inner membrane component Oant_3715 212 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 153011258 Common - transcriptional regulator, MarR family Oant_3938 19 COG1846 MarR, Transcriptional regulators Transcription 153010357 Common - cytochrome B561 Oant_3034 46 COG3038 CybB, Cytochrome B561 Energy production and conversion 153011324 Common - hypothetical protein Oant_4004 45 COG0657 Aes, Esterase/lipase Lipid metabolism 153010727 Common - ABC transporter related Oant_3406 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153011771 Common - Cobyrinic acid ac-diamide synthase Oant_4456 198 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 153010090 Common - short-chain dehydrogenase/reductase SDR Oant_2766 223 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153010124 Common - extracellular solute-binding protein family 3 Oant_2800 167 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153010215 Common - nitrate reductase, beta subunit Oant_2892 149 COG1140 NarY, Nitrate reductase beta subunit Energy production and conversion 153010762 Common - glycosyl transferase group 1 Oant_3441 110 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153011725 Pathogen - hypothetical protein Oant_4410 3 None None None 153010623 Common - Peptidyl-dipeptidase Dcp Oant_3302 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 153010353 Common - riboflavin biosynthesis protein RibF Oant_3030 211 COG0196 RibF, FAD synthase Coenzyme metabolism 153011133 Common - ribosomal RNA methyltransferase RrmJ/FtsJ Oant_3812 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 153011110 Common - 2OG-Fe(II) oxygenase Oant_3789 53 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 153010444 Pathogen - hypothetical protein Oant_3121 1 None None None 153011350 Common - 3-hydroxyacyl-CoA dehydrogenase NAD-binding Oant_4031 179 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 153010613 Common - OsmC family protein Oant_3292 98 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 153010673 Common - Domain of unknown function DUF1801 Oant_3352 27 COG5649 COG5649, Uncharacterized conserved protein Function unknown 153010778 Common - ABC transporter related Oant_3457 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153010555 Common - protein of unknown function DUF411 Oant_3232 62 COG3019 COG3019, Predicted metal-binding protein General function prediction only 153011600 Common - protein-L-isoaspartate O-methyltransferase Oant_4285 155 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 153010594 Pathogen - hypothetical protein Oant_3271 1 COG4282 SMI1, Protein involved in beta-1,3-glucan synthesis Carbohydrate transport and metabolism 153011578 Common - Homospermidine synthase Oant_4263 25 COG5310 COG5310, Homospermidine synthase Secondary metabolites biosynthesis, transport, and catabolism 153010273 Common - putative transcriptional regulator, MerR family Oant_2950 53 COG0789 SoxR, Predicted transcriptional regulators Transcription 153010535 Common - P-type conjugative transfer ATPase TrbB Oant_3212 152 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 153011274 Common - metal dependent phosphohydrolase Oant_3954 63 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 153010424 Common - Xylose isomerase domain protein TIM barrel Oant_3101 7 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 153011448 Common - regulatory protein ArsR Oant_4133 125 COG0640 ArsR, Predicted transcriptional regulators Transcription 153011551 Common - oxidoreductase domain protein Oant_4236 163 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153011674 Common - GCN5-related N-acetyltransferase Oant_4359 35 None None None 153010914 Common - ABC transporter related Oant_3593 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 153011479 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_4164 28 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 153010921 Common - Alkaline phosphatase Oant_3600 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010859 Common - hypothetical protein Oant_3538 37 COG1510 COG1510, Predicted transcriptional regulators Transcription 153011497 Common - hypothetical protein Oant_4182 10 None None None 153011719 Common - transcriptional regulator, LysR family Oant_4404 188 COG0583 LysR, Transcriptional regulator Transcription 153011654 Common - hypothetical protein Oant_4339 41 None None None 153011555 Common - glycosyl transferase, WecB/TagA/CpsF family Oant_4240 108 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 153011188 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Oant_3868 238 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 153010231 Common - transcriptional regulator, DeoR family Oant_2908 66 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 153011038 Common - extracellular solute-binding protein family 1 Oant_3717 93 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 153010949 Common - GCN5-related N-acetyltransferase Oant_3628 41 COG0456 RimI, Acetyltransferases General function prediction only 153011074 Common - ABC transporter related Oant_3753 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153011691 Common - hypothetical protein Oant_4376 26 None None None 153011686 Common - periplasmic binding protein/LacI transcriptional regulator Oant_4371 81 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010139 Common - short-chain dehydrogenase/reductase SDR Oant_2815 237 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 153010580 Common - IucA/IucC family protein Oant_3257 46 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 153010697 Common - acetyltransferase, CysE/LacA/LpxA/NodL family Oant_3376 114 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 153011200 Common - TRAP dicarboxylate transporter- DctP subunit Oant_3880 80 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 153010541 Common - P-type conjugative transfer protein TrbL Oant_3218 28 COG3846 TrbL, Type IV secretory pathway, TrbL components Intracellular trafficking and secretion 153010940 Common - transport system permease protein Oant_3619 174 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153010296 Pathogen - hypothetical protein Oant_2973 2 None None None 153011141 Common - protein of unknown function DUF442 Oant_3820 41 COG3453 COG3453, Uncharacterized protein conserved in bacteria Function unknown 153010844 Common - molybdenum cofactor synthesis domain protein Oant_3523 188 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 153010818 Common - polar amino acid ABC transporter, inner membrane subunit Oant_3497 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153011148 Common - Superoxide dismutase Oant_3827 87 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 153010438 Common - peptidase U32 Oant_3115 48 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 153011619 Common - short-chain dehydrogenase/reductase SDR Oant_4304 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153011430 Common - hypothetical protein Oant_4113 2 None None None 153010781 Common - periplasmic binding protein/LacI transcriptional regulator Oant_3460 119 COG1609 PurR, Transcriptional regulators Transcription 153011464 Common - transcriptional regulator, LysR family Oant_4149 191 COG0583 LysR, Transcriptional regulator Transcription 153011419 Common - protein of unknown function DUF1109 Oant_4102 19 COG4944 COG4944, Uncharacterized protein conserved in bacteria Function unknown 153011568 Common - molybdate ABC transporter, inner membrane subunit Oant_4253 184 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 153010603 Common - hypothetical protein Oant_3281 2 None None None 153010510 Common - hypothetical protein Oant_3187 16 None None None 153011329 Common - major facilitator superfamily MFS_1 Oant_4009 174 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 153010887 Common - L-rhamnose 1-epimerase Oant_3566 38 COG3254 COG3254, Uncharacterized conserved protein Function unknown 153011245 Common - Ornithine carbamoyltransferase Oant_3925 200 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153010336 Common - 2,5-didehydrogluconate reductase Oant_3013 189 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 153011193 Common - FAD linked oxidase domain protein Oant_3873 82 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 153011437 Common - putative PTS IIA-like nitrogen-regulatory protein PtsN Oant_4120 29 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 153010105 Common - extracellular solute-binding protein family 5 Oant_2781 199 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153010928 Common - Gluconate 2-dehydrogenase (acceptor) Oant_3607 73 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 153011668 Common - amidohydrolase Oant_4353 173 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 153010806 Common - protein of unknown function DUF899 thioredoxin family protein Oant_3485 28 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 153010883 Common - aminotransferase class IV Oant_3562 205 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 153010302 Common - NMT1/THI5 like domain protein Oant_2979 88 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 153011174 Common - extracellular solute-binding protein family 1 Oant_3854 91 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010412 Common - binding-protein-dependent transport systems inner membrane component Oant_3089 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011391 Common - hypothetical protein Oant_4073 14 None None None 153010683 Common - response regulator receiver protein Oant_3362 28 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 153011125 Common - extracellular solute-binding protein family 5 Oant_3804 205 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153011158 Common - PfkB domain protein Oant_3837 166 COG3892 COG3892, Uncharacterized protein conserved in bacteria Function unknown 153010832 Pathogen - hypothetical protein Oant_3511 2 None None None 153011512 Common - conserved hypothetical MotC chemotaxis protein Oant_4197 11 None None None 153010539 Common - P-type conjugative transfer protein TrbJ Oant_3216 24 COG5314 COG5314, Conjugal transfer/entry exclusion protein Intracellular trafficking and secretion 153010982 Common - GCN5-related N-acetyltransferase Oant_3661 67 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 153011537 Common - flagellar biosynthetic protein FlhB Oant_4222 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 153010946 Common - hypothetical protein Oant_3625 8 None None None 153011740 Common - Transposase and inactivated derivatives-like protein Oant_4425 47 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 153010208 Common - hypothetical protein Oant_2885 2 None None None 153010407 Common - peptidase T2 asparaginase 2 Oant_3084 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 153010787 Common - Ectoine utilization protein EutE Oant_3466 52 COG3608 COG3608, Predicted deacylase General function prediction only 153010220 Common - transcriptional regulator, GntR family Oant_2897 128 COG1802 GntR, Transcriptional regulators Transcription 153010865 Common - transcriptional regulator, GntR family Oant_3544 134 COG2188 PhnF, Transcriptional regulators Transcription 153011221 Common - Tripartite ATP-independent periplasmic transporter DctQ component Oant_3901 67 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 153010501 Common - single-strand binding protein Oant_3178 167 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 153011303 Common - isochorismatase hydrolase Oant_3983 67 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 153010964 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Oant_3643 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 153010851 Common - HI0933 family protein Oant_3530 31 COG4529 COG4529, Uncharacterized protein conserved in bacteria Function unknown 153011508 Common - flagellar basal body FlaE domain protein Oant_4193 128 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 153010199 Common - outer membrane autotransporter barrel domain protein Oant_2876 113 COG4625 COG4625, Uncharacterized protein with a C-terminal OMP (outer membrane protein) domain Function unknown 153010930 Common - hypothetical protein Oant_3609 19 None None None 153010794 Common - protein of unknown function DUF488 Oant_3473 76 COG3189 COG3189, Uncharacterized conserved protein Function unknown 153011580 Common - lipoprotein Omp10 Oant_4265 7 None None None 153011501 Common - flagellar biosynthesis protein FlhA Oant_4186 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 153010568 Common - protein of unknown function DUF305 Oant_3245 22 COG3544 COG3544, Uncharacterized protein conserved in bacteria Function unknown 153010279 Common - peptidase M42 family protein Oant_2956 74 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 153011519 Common - flagellar basal body-associated protein FliL Oant_4204 11 None None None 153011712 Common - ABC transporter related Oant_4397 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153011331 Common - major facilitator superfamily MFS_1 Oant_4011 187 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010217 Common - respiratory nitrate reductase, gamma subunit Oant_2894 58 COG2181 NarI, Nitrate reductase gamma subunit Energy production and conversion 153011294 Common - type I secretion system ATPase Oant_3974 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 153010598 Pathogen - hypothetical protein Oant_3276 1 None None None 153011376 Common - hypothetical protein Oant_4058 21 COG3823 COG3823, Glutamine cyclotransferase Posttranslational modification, protein turnover, chaperones 153010975 Common - diguanylate cyclase Oant_3654 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153010628 Common - inner-membrane translocator Oant_3307 106 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 153010226 Common - Inositol phosphatase/fructose-16-bisphosphatase Oant_2903 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 153010355 Common - isoleucyl-tRNA synthetase Oant_3032 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153010523 Common - protein tyrosine phosphatase Oant_3200 119 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 153010827 Common - ABC transporter related Oant_3506 249 COG4525 TauB, ABC-type taurine transport system, ATPase component Inorganic ion transport and metabolism 153010236 Common - ABC transporter related Oant_2913 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153010621 Common - hypothetical protein Oant_3300 22 COG5515 COG5515, Uncharacterized conserved small protein Function unknown 153010754 Common - Methyltransferase type 11 Oant_3433 21 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153011607 Pathogen - hypothetical protein Oant_4292 1 None None None 153011671 Common - transcriptional regulator, BadM/Rrf2 family Oant_4356 177 COG1959 COG1959, Predicted transcriptional regulator Transcription 153010337 Common - ErfK/YbiS/YcfS/YnhG family protein Oant_3014 89 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153011576 Common - para-aminobenzoate synthase, subunit I Oant_4261 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 153011726 Common - protein of unknown function DUF995 Oant_4411 6 None None None 153010902 Common - Histidinol dehydrogenase Oant_3581 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 153010351 Common - hypothetical protein Oant_3028 19 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 153011112 Common - ABC transporter related Oant_3791 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 153010097 Common - ABC transporter related Oant_2773 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010593 Common - hypothetical protein Oant_3270 46 None None None 153010758 Common - type I secretion system ATPase Oant_3437 249 COG4618 ArpD, ABC-type protease/lipase transport system, ATPase and permease components General function prediction only 153011307 Common - isochorismatase hydrolase Oant_3987 83 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 153011727 Common - endoglucanase family protein Oant_4412 19 COG4124 ManB, Beta-mannanase Carbohydrate transport and metabolism 153010303 Common - 5-formyltetrahydrofolate cyclo-ligase Oant_2980 20 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 153010958 Common - Invasion associated locus B family protein Oant_3637 17 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 153011563 Common - protein of unknown function DUF1007 Oant_4248 34 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 153010899 Common - ABC transporter, periplasmic solute-binding protein Oant_3578 46 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 153010574 Common - integral membrane sensor signal transduction histidine kinase Oant_3251 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153011521 Common - hypothetical protein Oant_4206 14 COG3334 COG3334, Uncharacterized conserved protein Function unknown 153010232 Common - EryC, D-erythrulose-1-phosphate dehydrogenase Oant_2909 8 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 153010321 Common - glutamate--cysteine ligase Oant_2998 54 COG3572 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 153011720 Common - extracellular solute-binding protein family 5 Oant_4405 213 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153011389 Common - Glycerone kinase Oant_4071 94 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 153011629 Common - Ku family containing protein Oant_4314 63 COG1273 COG1273, Uncharacterized conserved protein Function unknown 153010688 Common - putative transcriptional regulator, Crp/Fnr family Oant_3367 75 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153011160 Common - Xylose isomerase domain protein TIM barrel Oant_3839 59 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 153011045 Common - transcriptional regulator, LysR family Oant_3724 189 COG0583 LysR, Transcriptional regulator Transcription 153011321 Common - ABC transporter related Oant_4001 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153010935 Common - putative signal peptide protein Oant_3614 43 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153011228 Common - GAF sensor signal transduction histidine kinase Oant_3908 139 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 153011382 Common - Monosaccharide-transporting ATPase Oant_4064 134 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153011281 Common - metal dependent phosphohydrolase Oant_3961 50 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 153011741 Common - Shikimate dehydrogenase substrate binding domain protein Oant_4426 181 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 153010446 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Oant_3123 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 153010703 Common - glycosyl transferase family 2 Oant_3382 174 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153011095 Common - protein of unknown function DUF81 Oant_3774 40 COG0730 COG0730, Predicted permeases General function prediction only 153010494 Common - PilT protein domain protein Oant_3171 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 153011392 Common - FAD dependent oxidoreductase Oant_4074 89 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153011279 Common - Methylenetetrahydrofolate dehydrogenase (NADP(+)) Oant_3959 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 153010362 Common - peptidase M16 domain protein Oant_3039 184 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 153010153 Common - helix-turn-helix- domain containing protein AraC type Oant_2830 131 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153010643 Common - hypothetical protein Oant_3322 22 None None None 153010499 Common - hypothetical protein Oant_3176 21 None None None 153011443 Common - response regulator receiver protein Oant_4126 205 COG4566 TtrR, Response regulator Signal transduction mechanisms 153011620 Common - protein of unknown function DUF296 Oant_4305 30 COG1661 COG1661, Predicted DNA-binding protein with PD1-like DNA-binding motif General function prediction only 153011064 Common - hypothetical protein Oant_3743 7 None None None 153011422 Common - HupC/HyaC/HydC family protein Oant_4105 22 COG4117 COG4117, Thiosulfate reductase cytochrome B subunit (membrane anchoring protein) Energy production and conversion 153011313 Common - LrgB family protein Oant_3993 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 153011703 Common - ATPase associated with various cellular activities AAA_5 Oant_4388 77 COG0714 COG0714, MoxR-like ATPases General function prediction only 153010711 Common - C-methyltransferase Oant_3390 42 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 153010974 Pathogen - hypothetical protein Oant_3653 1 None None None 153010440 Common - hypothetical protein Oant_3117 14 COG3154 COG3154, Putative lipid carrier protein Lipid metabolism 153010638 Common - ABC transporter related Oant_3317 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153011734 Common - Asp/Glu racemase Oant_4419 45 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 153011135 Common - ABC transporter related Oant_3814 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153011606 Common - hypothetical protein Oant_4291 25 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 153010472 Common - domain of unknown function DUF1738 Oant_3149 48 COG4227 COG4227, Antirestriction protein DNA replication, recombination, and repair 153011087 Common - Xylose isomerase domain protein TIM barrel Oant_3766 15 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 153010377 Common - Catalase Oant_3054 127 COG0753 KatE, Catalase Inorganic ion transport and metabolism 153010135 Common - regulatory protein LacI Oant_2811 121 COG1609 PurR, Transcriptional regulators Transcription 153010648 Common - Carboxymethylenebutenolidase Oant_3327 110 COG0412 COG0412, Dienelactone hydrolase and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 153010550 Common - drug resistance transporter, EmrB/QacA subfamily Oant_3227 182 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153011142 Pathogen - hypothetical protein Oant_3821 2 None None None 153010319 Common - exodeoxyribonuclease VII, large subunit Oant_2996 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 153010366 Common - inositol monophosphatase Oant_3043 188 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 153010666 Common - periplasmic binding protein/LacI transcriptional regulator Oant_3345 103 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153011149 Common - multicopper oxidase type 3 Oant_3828 124 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 153011298 Common - ABC transporter related Oant_3978 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153010651 Common - phospholipase/Carboxylesterase Oant_3330 33 COG0400 COG0400, Predicted esterase General function prediction only 153011682 Common - Dak phosphatase Oant_4367 58 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 153010816 Pathogen - hypothetical protein Oant_3495 1 None None None 153011542 Common - drug resistance transporter, EmrB/QacA subfamily Oant_4227 199 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153011463 Common - ChaC family protein Oant_4148 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 153011730 Common - glycosyl transferase, group 2 family protein Oant_4415 76 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153011692 Common - hypothetical protein Oant_4377 12 None None None 153010477 Common - hypothetical protein Oant_3154 4 None None None 153010704 Common - polysaccharide pyruvyl transferase Oant_3383 26 COG2327 WcaK, Uncharacterized conserved protein Function unknown 153010349 Common - chaperonin GroEL Oant_3026 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 153011388 Common - dihydroxyacetone kinase, L subunit Oant_4070 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 153010469 Common - hypothetical protein Oant_3146 76 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 153011753 Common - binding-protein-dependent transport systems inner membrane component Oant_4438 209 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 153010686 Common - TOBE domain protein Oant_3365 23 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 153010345 Common - fumarate hydratase, class II Oant_3022 229 COG0114 FumC, Fumarase Energy production and conversion 153010255 Common - hypothetical protein Oant_2932 25 None None None 153010992 Common - DNA topoisomerase I Oant_3671 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 153011107 Common - binding-protein-dependent transport systems inner membrane component Oant_3786 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011366 Pathogen - hypothetical protein Oant_4047 2 None None None 153011165 Common - binding-protein-dependent transport systems inner membrane component Oant_3844 216 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 153010748 Common - protein of unknown function UPF0118 Oant_3427 148 COG0628 PerM, Predicted permease General function prediction only 153011400 Common - transport system permease protein Oant_4082 185 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 153011634 Common - hypothetical protein Oant_4319 2 None None None 153010823 Common - thiamine pyrophosphate protein central region Oant_3502 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 153010675 Common - protein of unknown function DUF1330 Oant_3354 10 COG5470 COG5470, Uncharacterized conserved protein Function unknown 153011230 Common - ABC transporter related Oant_3910 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153010092 Common - peptidase M24 Oant_2768 233 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 153010735 Common - D-xylose ABC transporter, periplasmic substrate-binding protein Oant_3414 87 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 153010559 Common - hypothetical protein Oant_3236 16 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 153011528 Common - hypothetical protein Oant_4213 5 None None None 153010595 Common - hypothetical protein Oant_3272 39 None None None 153010991 Pathogen - hypothetical protein Oant_3670 1 None None None 153011080 Common - NAD-dependent epimerase/dehydratase Oant_3759 122 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153010783 Common - Ectoine/hydroxyectoine ABC transporter ATP-binding protein Oant_3462 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153011478 Common - potassium efflux system protein Oant_4163 204 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 153011302 Common - extracellular solute-binding protein family 1 Oant_3982 35 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153011340 Common - beta-ketoadipyl CoA thiolase Oant_4020 167 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 153011764 Common - protein of unknown function DUF839 Oant_4449 70 COG3211 PhoX, Predicted phosphatase General function prediction only 153010484 Common - hypothetical protein Oant_3161 4 None None None 153011468 Common - binding-protein-dependent transport systems inner membrane component Oant_4153 229 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153010874 Common - catalytic domain of components of various dehydrogenase complexes Oant_3553 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 153010561 Common - Oxidoreductase FAD-binding domain protein Oant_3238 177 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 153010985 Common - Holliday junction resolvase YqgF Oant_3664 162 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 153011666 Common - polar amino acid ABC transporter, inner membrane subunit Oant_4351 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153010133 Common - Monosaccharide-transporting ATPase Oant_2809 168 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153010240 Common - carbohydrate kinase FGGY Oant_2917 171 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 153010825 Common - protein of unknown function DUF1486 Oant_3504 13 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 153010763 Common - polysaccharide pyruvyl transferase Oant_3442 11 None None None 153010569 Common - Redoxin domain protein Oant_3246 134 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 153011646 Common - transcriptional regulator, XRE family Oant_4331 45 COG1476 COG1476, Predicted transcriptional regulators Transcription 153011012 Common - hypothetical protein Oant_3691 23 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 153010533 Common - Bile acid:sodium symporter Oant_3210 32 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 153011019 Common - periplasmic solute binding protein Oant_3698 172 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 153010581 Common - major facilitator superfamily MFS_1 Oant_3258 21 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010165 Common - ABC transporter related Oant_2842 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153010222 Common - Malate/L-lactate dehydrogenase Oant_2899 67 COG2055 COG2055, Malate/L-lactate dehydrogenases Energy production and conversion 153011156 Common - Inositol 2-dehydrogenase Oant_3835 172 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153011462 Pathogen - hypothetical protein Oant_4147 1 None None None 153010170 Common - transcriptional regulator, LysR family Oant_2847 187 COG0583 LysR, Transcriptional regulator Transcription 153010312 Common - regulatory protein IclR Oant_2989 102 COG1414 IclR, Transcriptional regulator Transcription 153011291 Common - lysyl-tRNA synthetase Oant_3971 77 COG1384 LysS, Lysyl-tRNA synthetase (class I) Translation, ribosomal structure and biogenesis 153010788 Common - Ectoine utilization protein EutD Oant_3467 183 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 153011680 Common - extracellular solute-binding protein family 3 Oant_4365 177 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153010977 Common - protein of unknown function DUF6 transmembrane Oant_3656 137 COG2962 RarD, Predicted permeases General function prediction only 153011267 Common - branched-chain amino acid transport Oant_3947 13 COG4541 COG4541, Predicted membrane protein Function unknown 153011227 Common - two component transcriptional regulator, LuxR family Oant_3907 151 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 153010963 Common - ATP-dependent DNA helicase RecG Oant_3642 220 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 153010193 Common - hypothetical protein Oant_2870 7 COG3319 COG3319, Thioesterase domains of type I polyketide synthases or non-ribosomal peptide synthetases Secondary metabolites biosynthesis, transport, and catabolism 153011353 Common - hypothetical protein Oant_4034 3 None None None 153010830 Common - OmpA/MotB domain protein Oant_3509 66 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 153011531 Common - protein of unknown function DUF1217 Oant_4216 20 None None None 153011242 Pathogen - hypothetical protein Oant_3922 1 None None None 153010179 Common - histone deacetylase superfamily Oant_2856 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 153011453 Common - alanine racemase domain protein Oant_4138 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 153011617 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Oant_4302 167 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153010305 Common - monooxygenase FAD-binding Oant_2982 30 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 153010998 Common - response regulator receiver modulated diguanylate cyclase Oant_3677 225 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 153011114 Common - aminotransferase class I and II Oant_3793 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153010281 Common - binding-protein-dependent transport systems inner membrane component Oant_2958 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010701 Common - glycosyl transferase family 4 Oant_3380 84 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 153011190 Common - ABC transporter related Oant_3870 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 153010848 Common - 20S proteasome A and B subunits Oant_3527 54 COG3484 COG3484, Predicted proteasome-type protease Posttranslational modification, protein turnover, chaperones 153010944 Common - TonB-dependent heme/hemoglobin receptor family protein Oant_3623 107 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 153010431 Common - short-chain dehydrogenase/reductase SDR Oant_3108 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153011310 Common - secretion protein HlyD family protein Oant_3990 156 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 153011493 Common - ABC-3 protein Oant_4178 197 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 153011540 Common - transcriptional regulator, TetR family Oant_4225 144 COG1309 AcrR, Transcriptional regulator Transcription 153010925 Common - hypothetical protein Oant_3604 5 None None None 153010910 Common - NMT1/THI5 like domain protein Oant_3589 46 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 153010267 Common - protein of unknown function DUF1037 Oant_2944 19 COG4813 ThuA, Trehalose utilization protein Carbohydrate transport and metabolism 153011024 Common - extracellular solute-binding protein family 1 Oant_3703 20 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 153011211 Common - alanine racemase domain protein Oant_3891 70 COG3616 COG3616, Predicted amino acid aldolase or racemase Amino acid transport and metabolism 153010881 Common - RND efflux system, outer membrane lipoprotein, NodT family Oant_3560 125 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 153010923 Common - ABC transporter related Oant_3602 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 153011413 Common - Mannitol dehydrogenase domain protein Oant_4096 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 153010617 Common - protein of unknown function DUF1025 Oant_3296 48 COG3824 COG3824, Uncharacterized protein conserved in bacteria Function unknown 153010297 Common - transcriptional regulator, LysR family Oant_2974 109 COG0583 LysR, Transcriptional regulator Transcription 153010079 Common - hypothetical protein Oant_2754 4 None None None 153011435 Common - SAF domain protein Oant_4118 36 COG4091 COG4091, Predicted homoserine dehydrogenase Amino acid transport and metabolism 153010144 Common - adenosylmethionine-8-amino-7-oxononanoate aminotransferase Oant_2820 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 153010459 Common - hypothetical protein Oant_3136 2 None None None 153011709 Common - transcriptional regulator, LysR family Oant_4394 166 COG0583 LysR, Transcriptional regulator Transcription 153010525 Common - hypothetical protein Oant_3202 3 None None None 153011565 Common - hypothetical protein Oant_4250 3 None None None 153010738 Common - hypothetical protein Oant_3417 6 None None None 153010480 Common - Mercuric transport protein MerT Oant_3157 22 None None None 153010414 Common - ABC transporter related Oant_3091 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011272 Common - transcriptional regulator, GntR family Oant_3952 105 COG1802 GntR, Transcriptional regulators Transcription 153011762 Common - ribokinase Oant_4447 192 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153010801 Common - sodium:dicarboxylate symporter Oant_3480 161 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 153010328 Pathogen - hypothetical protein Oant_3005 2 None None None 153011502 Common - flagellar biosynthetic protein FliQ Oant_4187 58 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 153010857 Common - monovalent cation/proton antiporter, MnhG/PhaG subunit Oant_3536 19 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 153010912 Common - ABC transporter related Oant_3591 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 153011204 Common - BA14K family protein Oant_3884 7 None None None 153011474 Common - alanine dehydrogenase Oant_4159 167 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 153011175 Common - periplasmic binding protein/LacI transcriptional regulator Oant_3855 126 COG1609 PurR, Transcriptional regulators Transcription 153011183 Common - glycine cleavage system H protein Oant_3863 188 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 153010290 Common - NAD-dependent epimerase/dehydratase Oant_2967 213 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153011653 Common - formate/nitrite transporter Oant_4338 67 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 153011713 Common - ABC transporter related Oant_4398 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153010811 Common - major facilitator superfamily MFS_1 Oant_3490 109 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010118 Pathogen - hypothetical protein Oant_2794 1 None None None 153011572 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Oant_4257 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 153011202 Common - aldehyde dehydrogenase Oant_3882 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153010573 Common - ErfK/YbiS/YcfS/YnhG family protein Oant_3250 64 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153011213 Common - ABC transporter related Oant_3893 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153010681 Common - transcriptional regulator, TetR family Oant_3360 61 COG1309 AcrR, Transcriptional regulator Transcription 153010527 Common - cytochrome c biogenesis protein transmembrane region Oant_3204 131 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 153011043 Common - helix-turn-helix- domain containing protein AraC type Oant_3722 80 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153011041 Common - 3-oxoacid CoA-transferase, A subunit Oant_3720 101 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 153011384 Common - Monosaccharide-transporting ATPase Oant_4066 159 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153011249 Common - protein of unknown function DUF955 Oant_3929 51 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 153011091 Pathogen - hypothetical protein Oant_3770 1 None None None 153010845 Common - protein of unknown function DUF404 Oant_3524 89 COG2308 COG2308, Uncharacterized conserved protein Function unknown 153011130 Common - polar amino acid ABC transporter, inner membrane subunit Oant_3809 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153011300 Common - binding-protein-dependent transport systems inner membrane component Oant_3980 155 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153011445 Common - ABC transporter related Oant_4130 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153010496 Common - Antirestriction protein Oant_3173 17 None None None 153011154 Common - transcriptional regulator, LysR family Oant_3833 189 COG0583 LysR, Transcriptional regulator Transcription 153010833 Common - NMT1/THI5 like domain protein Oant_3512 51 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 153011048 Common - protocatechuate 3,4-dioxygenase, beta subunit Oant_3727 51 COG3485 PcaH, Protocatechuate 3,4-dioxygenase beta subunit Secondary metabolites biosynthesis, transport, and catabolism 153011499 Pathogen - hypothetical protein Oant_4184 2 None None None 153010583 Common - TonB-dependent receptor Oant_3260 110 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 153011162 Common - DoxX family protein Oant_3841 25 COG2259 COG2259, Predicted membrane protein Function unknown 153010770 Common - transcriptional regulator, LysR family Oant_3449 172 COG0583 LysR, Transcriptional regulator Transcription 153011328 Common - alpha/beta hydrolase fold Oant_4008 69 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153011673 Common - luciferase family protein Oant_4358 93 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 153010517 Common - hypothetical protein Oant_3194 23 None None None 153011705 Common - aldehyde dehydrogenase Oant_4390 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153010335 Common - protein of unknown function DUF224 cysteine-rich region domain protein Oant_3012 186 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 153010756 Common - Hemolysin-type calcium-binding region Oant_3435 105 None None None 153011096 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Oant_3775 27 COG3573 COG3573, Predicted oxidoreductase General function prediction only 153010591 Common - putative transcriptional regulator, XRE family Oant_3268 68 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 153011523 Common - FlgA, flagellar basal-body P-ring formation protein Oant_4208 29 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 153011544 Pathogen - hypothetical protein Oant_4229 1 None None None 153011394 Common - polar amino acid ABC transporter, inner membrane subunit Oant_4076 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153010956 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family Oant_3635 122 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 153010752 Common - putative membrane-anchored protein Oant_3431 5 None None None 153011345 Common - aminotransferase class I and II Oant_4025 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153010721 Common - amino acid permease-associated region Oant_3400 132 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 153011254 Common - hypothetical protein Oant_3934 3 None None None 153011455 Common - benzoate transporter Oant_4140 59 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 153010709 Common - hypothetical protein Oant_3388 15 COG4310 COG4310, Uncharacterized protein conserved in bacteria with an aminopeptidase-like domain General function prediction only 153010277 Common - ribonucleoside-diphosphate reductase, alpha subunit Oant_2954 217 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 153010128 Common - binding-protein-dependent transport systems inner membrane component Oant_2804 198 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 153010909 Common - transcriptional regulator, LysR family Oant_3588 116 COG0583 LysR, Transcriptional regulator Transcription 153011744 Common - TRAP dicarboxylate transporter, DctP subunit Oant_4429 111 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 153011574 Common - two component, sigma54 specific, transcriptional regulator, Fis family Oant_4259 190 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 153011137 Common - binding-protein-dependent transport systems inner membrane component Oant_3816 145 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153010724 Common - major facilitator superfamily MFS_1 Oant_3403 178 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153011368 Common - Heavy metal transport/detoxification protein Oant_4050 19 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 153010684 Common - Endoribonuclease L-PSP Oant_3363 45 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153010343 Common - glutathione-dependent formaldehyde-activating GFA Oant_3020 52 COG3791 COG3791, Uncharacterized conserved protein Function unknown 153011722 Common - gamma-glutamyltransferase Oant_4407 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 153010900 Common - binding-protein-dependent transport systems inner membrane component Oant_3579 187 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 153011481 Common - Endoribonuclease L-PSP Oant_4166 82 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153011408 Common - TRAP dicarboxylate transporter, DctP subunit Oant_4091 98 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 153011755 Common - regulatory protein IclR Oant_4440 106 COG1414 IclR, Transcriptional regulator Transcription 153010416 Common - beta-lactamase Oant_3093 66 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 153010733 Common - xylulokinase Oant_3412 184 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 153010261 Common - cation diffusion facilitator family transporter Oant_2938 45 COG3965 COG3965, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 153011636 Common - hypothetical protein Oant_4321 16 None None None 153010347 Common - NADPH-dependent FMN reductase Oant_3024 38 COG0431 COG0431, Predicted flavoprotein General function prediction only 153011644 Common - yecA family protein Oant_4329 10 None None None 153011239 Common - protein of unknown function DUF112 transmembrane Oant_3919 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 153010790 Common - Ectoine utilization protein EutB Oant_3469 222 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 153011105 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Oant_3784 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010385 Common - ABC transporter related Oant_3062 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153010447 Common - ATPase BadF/BadG/BcrA/BcrD type Oant_3124 62 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 153011732 Common - NAD-dependent epimerase/dehydratase Oant_4417 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153010669 Common - protein of unknown function DUF21 Oant_3348 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 153010531 Common - heavy metal translocating P-type ATPase Oant_3208 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 153011729 Common - UDP-glucose 6-dehydrogenase Oant_4414 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 153010310 Common - amidohydrolase Oant_2987 31 COG3964 COG3964, Predicted amidohydrolase General function prediction only 153010994 Common - protein of unknown function DUF983 Oant_3673 29 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 153010677 Common - transcriptional regulator, XRE family Oant_3356 32 COG1396 HipB, Predicted transcriptional regulators Transcription 153010268 Common - oxidoreductase domain protein Oant_2945 180 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153010228 Common - sugar-phosphate isomerase, RpiB/LacA/LacB family Oant_2905 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 153011584 Common - KpsF/GutQ family protein Oant_4269 144 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 153010631 Common - basic membrane lipoprotein Oant_3310 101 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 153010463 Common - ATP-dependent endonuclease, OLD family protein Oant_3140 22 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 153010253 Common - transcriptional regulator, LysR family Oant_2930 140 COG0583 LysR, Transcriptional regulator Transcription 153011028 Common - HAD-superfamily hydrolase subfamily IA, variant 3 Oant_3707 4 None None None 153011008 Pathogen - hypothetical protein Oant_3687 1 None None None 153011695 Common - protein of unknown function DUF323 Oant_4380 69 COG1262 COG1262, Uncharacterized conserved protein Function unknown 153011284 Common - ABC transporter related Oant_3964 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153011373 Common - protein of unknown function DUF899 thioredoxin family protein Oant_4055 29 COG4312 COG4312, Uncharacterized protein conserved in bacteria Function unknown 153011766 Common - major facilitator superfamily MFS_1 Oant_4451 56 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153011420 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Oant_4103 93 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153011434 Common - Pyruvate dehydrogenase (acetyl-transferring) Oant_4117 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 153010368 Common - protein of unknown function DUF374 Oant_3045 39 COG2121 COG2121, Uncharacterized protein conserved in bacteria Function unknown 153011736 Common - ABC transporter related Oant_4421 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153011051 Common - Extracellular ligand-binding receptor Oant_3730 132 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 153010081 Common - hypothetical protein Oant_2756 4 None None None 153010364 Common - potassium efflux system protein Oant_3041 182 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 153011428 Common - PTS system glucitol/sorbitol-specific IIA component Oant_4111 20 COG3731 SrlB, Phosphotransferase system sorbitol-specific component IIA Carbohydrate transport and metabolism 153010793 Common - aminotransferase class-III Oant_3472 236 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 153011651 Common - Integrase catalytic region Oant_4336 124 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 153011089 Common - Xanthine/uracil/vitamin C permease Oant_3768 136 COG2252 COG2252, Permeases General function prediction only 153011406 Common - hypothetical protein Oant_4088 60 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 153010442 Common - 3-octaprenyl-4-hydroxybenzoate carboxy-lyase Oant_3119 152 COG0163 UbiX, 3-polyprenyl-4-hydroxybenzoate decarboxylase Coenzyme metabolism 153010317 Pathogen - protein of unknown function DUF1127 Oant_2994 2 None None None 153011072 Common - binding-protein-dependent transport systems inner membrane component Oant_3751 142 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153011610 Common - protein of unknown function DUF892 Oant_4295 36 COG3685 COG3685, Uncharacterized protein conserved in bacteria Function unknown 153011305 Common - transcriptional regulator, LysR family Oant_3985 170 COG0583 LysR, Transcriptional regulator Transcription 153010660 Common - binding-protein-dependent transport systems inner membrane component Oant_3339 95 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153011622 Common - cyclic nucleotide-binding protein Oant_4307 28 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153010799 Common - two component, sigma54 specific, transcriptional regulator, Fis family Oant_3478 223 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 153011058 Common - ABC transporter related Oant_3737 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010474 Common - hypothetical protein Oant_3151 61 None None None 153010653 Common - protein of unknown function DUF395 YeeE/YedE Oant_3332 60 COG2391 COG2391, Predicted transporter component General function prediction only 153011591 Common - glutamate synthase, NADH/NADPH, small subunit Oant_4276 187 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 153011311 Common - drug resistance transporter, EmrB/QacA subfamily Oant_3991 173 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010658 Common - ABC transporter, periplasmic substrate-binding protein Oant_3337 14 COG4134 COG4134, ABC-type uncharacterized transport system, periplasmic component General function prediction only 153010188 Common - formate dehydrogenase, gamma subunit Oant_2865 64 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 153010299 Common - 5-formyltetrahydrofolate cyclo-ligase Oant_2976 20 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 153010285 Common - asparagine synthase (glutamine-hydrolyzing) Oant_2962 182 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 153011293 Common - type I secretion membrane fusion protein, HlyD family Oant_3973 118 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 153010987 Common - aspartate carbamoyltransferase Oant_3666 240 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 153011588 Common - lytic murein transglycosylase Oant_4273 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 153010838 Common - GCN5-related N-acetyltransferase Oant_3517 8 COG3153 COG3153, Predicted acetyltransferase General function prediction only 153010505 Common - hypothetical protein Oant_3182 9 COG5419 COG5419, Uncharacterized conserved protein Function unknown 153011533 Common - surface presentation of antigens (SPOA) protein Oant_4218 51 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 153010546 Common - transcriptional regulator, LysR family Oant_3223 189 COG0583 LysR, Transcriptional regulator Transcription 153010323 Common - transcriptional regulator, MarR family Oant_3000 117 COG1846 MarR, Transcriptional regulators Transcription 153011129 Common - extracellular solute-binding protein family 3 Oant_3808 189 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153010861 Common - ABC transporter CydDC cysteine exporter (CydDC-E) family permease/ATP-binding protein CydC Oant_3540 247 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 153010877 Pathogen - hypothetical protein Oant_3556 1 None None None 153010403 Common - Cyclopropane-fatty-acyl-phospholipid synthase Oant_3080 142 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 153010813 Common - putative transcriptional regulator, GntR family Oant_3492 183 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153010259 Common - major facilitator superfamily MFS_1 Oant_2936 118 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 153011261 Common - cation diffusion facilitator family transporter Oant_3941 108 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 153011268 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Oant_3948 47 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153010970 Common - hypothetical protein Oant_3649 16 COG4425 COG4425, Predicted membrane protein Function unknown 153010224 Common - NnrS family protein Oant_2901 60 COG3213 NnrS, Uncharacterized protein involved in response to NO Inorganic ion transport and metabolism 153011451 Common - ferric iron reductase Oant_4136 9 COG4114 FhuF, Uncharacterized Fe-S protein General function prediction only 153011750 Common - BFD domain protein (2Fe-2S)-binding domain protein Oant_4435 85 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 153010433 Common - helix-turn-helix- domain containing protein AraC type Oant_3110 82 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153011232 Common - inner-membrane translocator Oant_3912 117 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153011214 Common - short-chain dehydrogenase/reductase SDR Oant_3894 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153011225 Common - GntR domain protein Oant_3905 155 COG2186 FadR, Transcriptional regulators Transcription 153010177 Common - protein of unknown function DUF849 Oant_2854 63 COG3246 COG3246, Uncharacterized conserved protein Function unknown 153011476 Common - protein of unknown function DUF930 Oant_4161 10 COG5373 COG5373, Predicted membrane protein Function unknown 153010509 Common - DNA methylase N-4/N-6 domain protein Oant_3186 80 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 153010690 Common - lipopolysaccharide biosynthesis protein Oant_3369 58 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 153010968 Common - virulence factor family protein Oant_3647 18 COG3946 VirJ, Type IV secretory pathway, VirJ component Intracellular trafficking and secretion 153010167 Common - transcriptional regulator, DeoR family Oant_2844 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 153010486 Common - hypothetical protein Oant_3163 15 None None None 153011071 Common - extracellular solute-binding protein family 1 Oant_3750 108 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010094 Common - binding-protein-dependent transport systems inner membrane component Oant_2770 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010872 Common - 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) Oant_3551 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 153010238 Common - periplasmic binding protein/LacI transcriptional regulator Oant_2915 96 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153011757 Common - ABC transporter related Oant_4442 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 153011342 Common - aminotransferase class V Oant_4022 124 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 153011664 Common - extracellular solute-binding protein family 3 Oant_4349 99 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153011031 Common - extracellular solute-binding protein family 3 Oant_3710 174 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153011662 Common - FMN-binding domain protein Oant_4347 85 COG3901 NosR, Regulator of nitric oxide reductase transcription Transcription 153010161 Common - ribokinase Oant_2838 198 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153010893 Common - rhamnulose-1-phosphate aldolase/alcohol dehydrogenase Oant_3572 231 COG3347 COG3347, Uncharacterized conserved protein Function unknown 153010937 Common - YbaK/prolyl-tRNA synthetase associated region Oant_3616 83 COG2606 EbsC, Uncharacterized conserved protein Function unknown 153011472 Common - Glutamate--ammonia ligase Oant_4157 43 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 153010897 Common - short-chain dehydrogenase/reductase SDR Oant_3576 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153010567 Common - hypothetical protein Oant_3244 21 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 153011515 Common - flagellar M-ring protein FliF Oant_4200 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 153010627 Common - inner-membrane translocator Oant_3306 115 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 153010246 Common - 3-hydroxyacyl-CoA dehydrogenase NAD-binding Oant_2923 108 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 153010731 Common - oxidoreductase domain protein Oant_3410 131 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153010326 Common - secretion protein HlyD family protein Oant_3003 144 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 153011159 Common - thiamine pyrophosphate protein central region Oant_3838 221 COG3962 COG3962, Acetolactate synthase Amino acid transport and metabolism 153010736 Common - D-xylose ABC transporter, ATPase subunit Oant_3415 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153011570 Common - Rhodanese domain protein Oant_4255 110 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 153010482 Pathogen - hypothetical protein Oant_3159 1 None None None 153011624 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Oant_4309 149 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153011347 Common - cyclase family protein Oant_4027 79 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 153010746 Common - protein of unknown function DUF81 Oant_3425 29 None None None 153010961 Common - transcription-repair coupling factor Oant_3640 217 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 153011457 Common - nucleoside recognition domain protein Oant_4142 18 None None None 153010174 Common - ABC transporter related Oant_2851 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153010453 Common - beta-lactamase Oant_3130 64 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 153010292 Pathogen - hypothetical protein Oant_2969 2 None None None 153010394 Common - transcriptional regulator, LysR family Oant_3071 186 COG0583 LysR, Transcriptional regulator Transcription 153011504 Common - flagellar FlbT family protein Oant_4189 24 COG5443 FlbT, Flagellar biosynthesis regulator FlbT Cell motility and secretion 153010183 Common - selenide, water dikinase Oant_2860 141 COG0709 SelD, Selenophosphate synthase Amino acid transport and metabolism 153011715 Common - inner-membrane translocator Oant_4400 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 153010143 Common - Beta-ketoacyl-acyl-carrier-protein synthase I Oant_2819 203 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 153010195 Common - hypothetical protein Oant_2872 16 None None None 153011170 Common - short-chain dehydrogenase/reductase SDR Oant_3850 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153011005 Pathogen - phage transcriptional regulator, AlpA Oant_3684 1 COG3311 AlpA, Predicted transcriptional regulator Transcription 153010155 Common - binding-protein-dependent transport systems inner membrane component Oant_2832 161 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 153011185 Common - protein of unknown function DUF1127 Oant_3865 8 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 153010400 Common - FAD dependent oxidoreductase Oant_3077 150 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 153010586 Common - polar amino acid ABC transporter, inner membrane subunit Oant_3263 175 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153010556 Common - heavy metal translocating P-type ATPase Oant_3233 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 153011240 Common - hypothetical protein Oant_3920 20 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 153011078 Common - GntR domain protein Oant_3757 147 COG2186 FadR, Transcriptional regulators Transcription 153011122 Common - hypothetical protein Oant_3801 8 None None None 153010868 Common - binding-protein-dependent transport systems inner membrane component Oant_3547 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153011177 Common - Dyp-type peroxidase family Oant_3857 47 COG2837 COG2837, Predicted iron-dependent peroxidase Inorganic ion transport and metabolism 153011558 Common - lipopolysaccharide biosynthesis protein Oant_4243 54 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 153010855 Common - cation antiporter Oant_3534 65 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 153011270 Common - Glutathione S-transferase domain protein Oant_3950 84 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153010428 Common - peptide deformylase Oant_3105 211 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 153011116 Common - TonB-dependent receptor Oant_3795 125 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 153010619 Common - hypothetical protein Oant_3298 9 None None None 153010761 Common - putative membrane-anchored protein Oant_3440 2 None None None 153010919 Common - extracellular solute-binding protein family 5 Oant_3598 211 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 153011199 Common - TRAP C4-dicarboxylate transport system permease DctM subunit Oant_3879 124 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 153010519 Common - major facilitator superfamily MFS_1 Oant_3196 37 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153011102 Common - hypothetical protein Oant_3781 18 None None None 153011678 Common - Mandelate racemase/muconate lactonizing protein Oant_4363 137 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 153010111 Common - transcriptional regulator, LysR family Oant_2787 192 COG0583 LysR, Transcriptional regulator Transcription 153011144 Common - binding-protein-dependent transport systems inner membrane component Oant_3823 162 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 153011052 Common - inner-membrane translocator Oant_3731 144 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 153010606 Common - peptidase S16 lon domain protein Oant_3285 35 COG2802 COG2802, Uncharacterized protein, similar to the N-terminal domain of Lon protease General function prediction only 153010951 Common - inner-membrane translocator Oant_3630 108 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 153011491 Common - periplasmic solute binding protein Oant_4176 160 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 153010609 Common - methylated-DNA--protein-cysteine methyltransferase Oant_3288 180 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 153011283 Common - pyrroline-5-carboxylate reductase Oant_3963 212 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 153010927 Common - AraC-type transcriptional regulator domain protein Oant_3606 108 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153010101 Common - periplasmic binding protein Oant_2777 40 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153011415 Common - secretion protein HlyD family protein Oant_4098 72 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 153011026 Common - binding-protein-dependent transport systems inner membrane component Oant_3705 214 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153010743 Common - protein of unknown function DUF1468 Oant_3422 17 None None None 153010515 Common - hypothetical protein Oant_3192 26 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 153011167 Common - putative transcriptional regulator, AsnC family Oant_3847 164 COG1522 Lrp, Transcriptional regulators Transcription 153011194 Common - NMT1/THI5 like domain protein Oant_3874 69 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 153011649 Common - phage integrase family protein Oant_4334 30 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 153010138 Common - inner-membrane translocator Oant_2814 108 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 153011687 Common - inner-membrane translocator Oant_4372 101 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153010324 Common - Fusaric acid resistance protein conserved region Oant_3001 51 COG1289 COG1289, Predicted membrane protein Function unknown 153010740 Common - hypothetical protein Oant_3419 5 None None None 153010108 Common - ABC transporter related Oant_2784 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153010929 Common - Gluconate 2-dehydrogenase (acceptor) Oant_3608 65 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 153010745 Common - transcriptional regulator, LysR family Oant_3424 190 COG0583 LysR, Transcriptional regulator Transcription 153011027 Common - periplasmic binding protein/LacI transcriptional regulator Oant_3706 126 COG1609 PurR, Transcriptional regulators Transcription 153010936 Common - hypothetical protein Oant_3615 11 COG3798 COG3798, Uncharacterized protein conserved in bacteria Function unknown 153011546 Common - binding-protein-dependent transport systems inner membrane component Oant_4231 191 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153010554 Pathogen - hypothetical protein Oant_3231 1 None None None 153011677 Common - hypothetical protein Oant_4362 14 COG3375 COG3375, Uncharacterized conserved protein Function unknown 153010886 Common - carbohydrate kinase FGGY Oant_3565 23 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 153010602 Pathogen - hypothetical protein Oant_3280 1 None None None 153010605 Common - thioredoxin Oant_3284 231 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 153011056 Common - adenine deaminase Oant_3735 78 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 153010943 Common - hypothetical protein Oant_3622 5 COG4256 HemP, Hemin uptake protein Inorganic ion transport and metabolism 153010819 Common - polar amino acid ABC transporter, inner membrane subunit Oant_3498 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153011569 Common - molybdenum ABC transporter, periplasmic molybdate-binding protein Oant_4254 151 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 153011500 Common - flagellar biosynthetic protein FliR Oant_4185 125 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 153010849 Common - extracellular solute-binding protein family 5 Oant_3528 196 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153011139 Common - 67-dimethyl-8-ribityllumazine synthase Oant_3818 150 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 153010904 Common - transcriptional regulator, GntR family Oant_3583 124 COG2188 PhnF, Transcriptional regulators Transcription 153011196 Common - transcriptional regulator, RpiR family Oant_3876 75 COG1737 RpiR, Transcriptional regulators Transcription 153011626 Common - signal transduction histidine kinase Oant_4311 58 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 153010269 Common - hypothetical protein Oant_2946 10 COG1511 COG1511, Predicted membrane protein Function unknown 153010418 Common - transcriptional regulator, LysR family Oant_3095 166 COG0583 LysR, Transcriptional regulator Transcription 153011669 Common - putative nitrilotriacetate monooxygenase component Oant_4354 66 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 153011490 Common - hypothetical protein Oant_4175 18 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 153011339 Common - 3-hydroxyacyl-CoA dehydrogenase NAD-binding Oant_4019 161 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 153011525 Common - flagellar hook-basal body complex protein FliE Oant_4210 31 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 153010181 Common - Carbonate dehydratase Oant_2858 150 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 153011173 Common - binding-protein-dependent transport systems inner membrane component Oant_3853 152 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153011696 Common - putative transcriptional regulator, Crp/Fnr family Oant_4381 173 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153011264 Common - major facilitator superfamily MFS_1 Oant_3944 163 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153011206 Common - protein of unknown function DUF6 transmembrane Oant_3886 72 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 153010262 Common - Alanine racemase Oant_2939 126 COG1609 PurR, Transcriptional regulators Transcription 153011718 Common - dihydrodipicolinate synthetase Oant_4403 205 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 153010542 Common - Conjugal transfer protein Oant_3219 34 COG3701 TrbF, Type IV secretory pathway, TrbF components Intracellular trafficking and secretion 153011556 Common - hypothetical protein Oant_4241 7 None None None 153010173 Common - polar amino acid ABC transporter, inner membrane subunit Oant_2850 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153011157 Common - transcriptional regulator, RpiR family Oant_3836 89 COG1737 RpiR, Transcriptional regulators Transcription 153011449 Pathogen - hypothetical protein Oant_4134 1 None None None 153010425 Common - Glycerone kinase Oant_3102 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 153011487 Common - ATPase BadF/BadG/BcrA/BcrD type Oant_4172 54 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 153011215 Common - extracellular solute-binding protein family 1 Oant_3895 127 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010293 Common - septum site-determining protein MinC Oant_2970 76 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 153010396 Common - ABC transporter related Oant_3073 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153011657 Common - NosL family protein Oant_4342 27 COG4314 NosL, Predicted lipoprotein involved in nitrous oxide reduction Energy production and conversion 153010454 Common - protein of unknown function UPF0075 Oant_3131 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 153010411 Common - extracellular solute-binding protein family 5 Oant_3088 197 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153011297 Common - ABC transporter related Oant_3977 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153010948 Common - MiaB-like tRNA modifying enzyme YliG Oant_3627 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 153011341 Common - transcriptional regulator, GntR family Oant_4021 122 COG1802 GntR, Transcriptional regulators Transcription 153011659 Common - ABC transporter related Oant_4344 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153010237 Common - Monosaccharide-transporting ATPase Oant_2914 118 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153011377 Common - transcriptional regulator, DeoR family Oant_4059 70 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 153010114 Common - binding-protein-dependent transport systems inner membrane component Oant_2790 215 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 153010809 Common - CutC family protein Oant_3488 59 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 153010896 Common - histidinol-phosphate aminotransferase Oant_3575 219 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 153011334 Common - NADH:flavin oxidoreductase/NADH oxidase Oant_4014 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 153010536 Common - Conjugal transfer protein TrbC Oant_3213 22 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 153011181 Common - hypothetical protein Oant_3861 2 None None None 153010276 Common - NrdI protein Oant_2953 35 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 153011552 Common - O-antigen polymerase Oant_4237 22 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 153011642 Common - IS66 Orf2 family protein Oant_4327 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153010988 Common - dihydroorotase, multifunctional complex type Oant_3667 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 153010854 Common - NADH/Ubiquinone/plastoquinone (complex I) Oant_3533 196 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 153011660 Common - periplasmic copper-binding Oant_4345 49 COG3420 NosD, Nitrous oxidase accessory protein Inorganic ion transport and metabolism 153011348 Common - hypothetical protein Oant_4029 11 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 153011507 Common - flagellar hook-associated protein FlgK Oant_4192 112 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 153010625 Common - GTP-binding protein TypA Oant_3304 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 153011699 Common - cytochrome c oxidase subunit III Oant_4384 155 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 153010358 Common - CMP/dCMP deaminase zinc-binding Oant_3035 213 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 153010196 Common - two component transcriptional regulator, LuxR family Oant_2873 210 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 153010487 Common - phage integrase domain protein SAM domain protein Oant_3164 12 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153010420 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Oant_3097 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 153010871 Common - ABC transporter related Oant_3550 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153011370 Common - glutaredoxin Oant_4052 9 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 153010870 Common - oxidoreductase domain protein Oant_3549 162 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153010646 Common - transcriptional regulator, LysR family Oant_3325 178 COG0583 LysR, Transcriptional regulator Transcription 153011711 Common - Aspartate dehydrogenase Oant_4396 49 COG1712 COG1712, Predicted dinucleotide-utilizing enzyme General function prediction only 153010878 Common - cell divisionFtsK/SpoIIIE Oant_3557 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 153010506 Common - putative transcriptional regulator Oant_3183 24 None None None 153010449 Common - extracellular solute-binding protein family 5 Oant_3126 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153011587 Common - UTP-glucose-1-phosphate uridylyltransferase Oant_4272 232 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 153010099 Common - anti-FecI sigma factor, FecR Oant_2775 45 COG3712 FecR, Fe2+-dicitrate sensor, membrane component Inorganic ion transport and metabolism / Signal transduction mechanisms 153011632 Pathogen - hypothetical protein Oant_4317 1 None None None 153011017 Common - helix-turn-helix- domain containing protein AraC type Oant_3696 127 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153010564 Common - Heavy metal transport/detoxification protein Oant_3241 34 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 153010892 Common - transcriptional regulator, DeoR family Oant_3571 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 153010680 Common - protein of unknown function DUF6 transmembrane Oant_3359 53 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 153011010 Pathogen - hypothetical protein Oant_3689 1 None None None 153010831 Pathogen - hypothetical protein Oant_3510 2 None None None 153010422 Common - hypothetical protein Oant_3099 15 None None None 153010967 Common - protein of unknown function DUF470 Oant_3646 76 COG2898 COG2898, Uncharacterized conserved protein Function unknown 153010205 Common - CDP-alcohol phosphatidyltransferase Oant_2882 49 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 153011275 Common - short-chain dehydrogenase/reductase SDR Oant_3955 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153010162 Common - hypothetical protein Oant_2839 15 None None None 153010644 Common - sulfatase Oant_3323 94 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 153011132 Common - Ppx/GppA phosphatase Oant_3811 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 153010665 Common - Dimethylmenaquinone methyltransferase Oant_3344 69 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 153010257 Common - putative methylisocitrate lyase Oant_2934 134 COG2513 PrpB, PEP phosphonomutase and related enzymes Carbohydrate transport and metabolism 153010399 Common - aldo/keto reductase Oant_3076 203 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 153011100 Common - osmosensitive K+ channel signal transduction histidine kinase Oant_3779 220 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 153010718 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Oant_3397 142 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153011356 Common - Peptidoglycan-binding domain 1 protein Oant_4037 118 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 153010096 Common - ABC transporter related Oant_2772 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011145 Common - extracellular solute-binding protein family 1 Oant_3824 112 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 153011318 Common - Extracellular ligand-binding receptor Oant_3998 140 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 153011083 Common - hypothetical protein Oant_3762 36 COG3970 COG3970, Fumarylacetoacetate (FAA) hydrolase family protein General function prediction only 153010475 Common - hypothetical protein Oant_3152 8 None None None 153010141 Common - outer membrane autotransporter barrel domain protein Oant_2817 67 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 153011596 Common - Lysophospholipase Oant_4281 53 COG2267 PldB, Lysophospholipase Lipid metabolism 153011590 Common - amino acid permease-associated region Oant_4275 174 COG1113 AnsP, Gamma-aminobutyrate permease and related permeases Amino acid transport and metabolism 153010301 Common - ABC transporter related Oant_2978 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 153011432 Common - biotin/lipoyl attachment domain protein Oant_4115 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 153010657 Common - dihydrodipicolinate synthetase Oant_3336 194 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 153010679 Common - transcriptional regulator, LysR family Oant_3358 177 COG0583 LysR, Transcriptional regulator Transcription 153011371 Common - efflux transporter, RND family, MFP subunit Oant_4053 149 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 153010330 Common - GntR domain protein Oant_3007 135 COG2186 FadR, Transcriptional regulators Transcription 153011118 Common - periplasmic binding protein Oant_3797 59 COG4607 CeuA, ABC-type enterochelin transport system, periplasmic component Inorganic ion transport and metabolism 153010634 Common - diguanylate cyclase Oant_3313 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153010339 Common - Lysine exporter protein (LYSE/YGGA) Oant_3016 114 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 153010622 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_3301 21 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 153011737 Common - inner-membrane translocator Oant_4422 163 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 153010191 Common - Sel1 domain protein repeat-containing protein Oant_2868 80 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 153010589 Common - Endoribonuclease L-PSP Oant_3266 157 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153010662 Common - Mandelate racemase/muconate lactonizing protein Oant_3341 109 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 153010372 Common - DNA mismatch repair protein MutL Oant_3049 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 153010708 Common - NAD-dependent epimerase/dehydratase Oant_3387 184 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153010455 Common - hypothetical protein Oant_3132 26 COG3915 COG3915, Uncharacterized protein conserved in bacteria Function unknown 153010380 Common - MTA/SAH nucleosidase family protein Oant_3057 27 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 153011076 Common - carbohydrate kinase, thermoresistant glucokinase family Oant_3755 80 COG3265 GntK, Gluconate kinase Carbohydrate transport and metabolism 153011069 Common - polar amino acid ABC transporter, inner membrane subunit Oant_3748 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153010084 Pathogen - hypothetical protein Oant_2759 1 None None None 153011483 Common - hypothetical protein Oant_4168 23 COG1289 COG1289, Predicted membrane protein Function unknown 153011604 Common - hypothetical protein Oant_4289 3 None None None 153011639 Common - hypothetical protein Oant_4324 4 None None None 153010375 Common - inosine-5'-monophosphate dehydrogenase Oant_3052 242 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 153011234 Common - ABC transporter related Oant_3914 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 153010340 Common - histidyl-tRNA synthetase Oant_3017 249 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153010250 Common - ABC-2 type transporter Oant_2927 126 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 153011361 Common - DEAD/H associated domain protein Oant_4042 186 COG1201 Lhr, Lhr-like helicases General function prediction only 153011164 Common - ABC transporter related Oant_3843 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153011360 Common - hypothetical protein Oant_4041 45 COG1407 COG1407, Predicted ICC-like phosphoesterases General function prediction only 153011536 Common - flagellar motor switch protein FliG Oant_4221 122 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 153010692 Common - NAD-dependent epimerase/dehydratase Oant_3371 209 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153011769 Common - replication protein C Oant_4454 15 None None None 153010820 Common - ABC transporter related Oant_3499 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153010726 Common - NAD-dependent epimerase/dehydratase Oant_3405 126 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153010978 Common - DNA topoisomerase IV, B subunit Oant_3657 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 153011259 Common - Chloride channel core Oant_3939 153 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 153010777 Common - binding-protein-dependent transport systems inner membrane component Oant_3456 151 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153010723 Pathogen - hypothetical protein Oant_3402 1 None None None 153010917 Common - extracellular solute-binding protein family 5 Oant_3596 212 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 153011675 Common - luciferase family protein Oant_4360 114 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 153010670 Common - diguanylate cyclase/phosphodiesterase Oant_3349 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 153011745 Common - TRAP dicarboxylate transporter, DctM subunit Oant_4430 122 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 153010805 Common - transcriptional regulator, MarR family Oant_3484 49 COG1846 MarR, Transcriptional regulators Transcription 153010614 Common - RNA-directed DNA polymerase (Reverse transcriptase) Oant_3293 94 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 153010406 Common - hypothetical protein Oant_3083 3 None None None 153010156 Common - extracellular solute-binding protein family 1 Oant_2833 110 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 153011343 Common - polar amino acid ABC transporter, inner membrane subunit Oant_4023 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153011033 Common - Saccharopine dehydrogenase Oant_3712 36 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 153010148 Common - ABC transporter related Oant_2824 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 153011306 Common - transcriptional regulator, LysR family Oant_3986 134 COG0583 LysR, Transcriptional regulator Transcription 153011022 Common - ABC-3 protein Oant_3701 194 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 153010954 Common - Alcohol dehydrogenase zinc-binding domain protein Oant_3633 200 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 153010773 Common - hypothetical protein Oant_3452 5 None None None 153010502 Common - transcriptional regulator, XRE family Oant_3179 13 None None None 153010383 Common - oxidoreductase domain protein Oant_3060 164 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153010216 Common - nitrate reductase molybdenum cofactor assembly chaperone Oant_2893 55 COG2180 NarJ, Nitrate reductase delta subunit Energy production and conversion 153011323 Common - benzoate-CoA ligase family Oant_4003 221 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 153011285 Common - ABC transporter related Oant_3965 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011337 Common - acyl-CoA dehydrogenase domain protein Oant_4017 149 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153011252 Pathogen - hypothetical protein Oant_3932 2 None None None 153010836 Common - integral membrane sensor signal transduction histidine kinase Oant_3515 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153011650 Common - transposase IS3/IS911 family protein Oant_4335 59 None None None 153011169 Common - Alcohol dehydrogenase GroES domain protein Oant_3849 206 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 153010578 Common - IucA/IucC family protein Oant_3255 50 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 153010389 Common - type III effector Hrp-dependent outers Oant_3066 48 COG3395 COG3395, Uncharacterized protein conserved in bacteria Function unknown 153010187 Common - formate dehydrogenase, beta subunit Oant_2864 160 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 153011694 Common - nitrite reductase, copper-containing Oant_4379 46 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 153010843 Common - extracellular solute-binding protein family 3 Oant_3522 167 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153011489 Common - cobalamin synthesis protein P47K Oant_4174 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 153010390 Common - Ribulose-bisphosphate carboxylase Oant_3067 67 COG1850 RbcL, Ribulose 1,5-bisphosphate carboxylase, large subunit Carbohydrate transport and metabolism 153011263 Common - Prephenate dehydrogenase Oant_3943 103 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 153010714 Common - secretion protein HlyD family protein Oant_3393 130 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 153010201 Common - efflux transporter, RND family, MFP subunit Oant_2878 164 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 153011396 Common - extracellular solute-binding protein family 3 Oant_4078 124 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153011425 Common - Glucitol operon activator Oant_4108 3 COG4578 GutM, Glucitol operon activator Transcription 153010308 Common - binding-protein-dependent transport systems inner membrane component Oant_2985 220 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010316 Common - Integral membrane protein TerC Oant_2993 98 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 153011498 Common - hypothetical protein Oant_4183 12 None None None 153011152 Common - alkylhydroperoxidase, AhpD family Oant_3831 27 COG2128 COG2128, Uncharacterized conserved protein Function unknown 153010123 Common - polar amino acid ABC transporter, inner membrane subunit Oant_2799 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153010127 Common - spermidine/putrescine ABC transporter ATPase subunit Oant_2803 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153011246 Common - binding-protein-dependent transport systems inner membrane component Oant_3926 210 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 153011098 Common - K+-transporting ATPase, B subunit Oant_3777 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 153011759 Common - inner-membrane translocator Oant_4444 82 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 153011667 Common - GCN5-related N-acetyltransferase Oant_4352 52 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 153010540 Common - hypothetical protein Oant_3217 11 None None None 153011266 Common - AzlC family protein Oant_3946 104 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 153011613 Common - hypothetical protein Oant_4298 9 None None None 153011690 Common - hypothetical protein Oant_4375 28 COG4309 COG4309, Uncharacterized conserved protein Function unknown 153011579 Pathogen - hypothetical protein Oant_4264 1 None None None 153011029 Common - aldo/keto reductase Oant_3708 192 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 153011509 Common - two component transcriptional regulator, winged helix family Oant_4194 158 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153010803 Common - YidE/YbjL duplication Oant_3482 57 COG2985 COG2985, Predicted permease General function prediction only 153010996 Common - major facilitator superfamily MFS_1 Oant_3675 100 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010423 Common - protein of unknown function DUF112 transmembrane Oant_3100 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 153010288 Common - FAD linked oxidase domain protein Oant_2965 48 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 153011640 Common - protein of unknown function DUF805 Oant_4325 49 COG3152 COG3152, Predicted membrane protein Function unknown 153011567 Common - molybdate ABC transporter, ATPase subunit Oant_4252 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 153011554 Common - hypothetical protein Oant_4239 31 None None None 153011447 Common - Activator of Hsp90 ATPase 1 family protein Oant_4132 18 COG3832 COG3832, Uncharacterized conserved protein Function unknown 153010931 Pathogen - hypothetical protein Oant_3610 2 None None None 153011655 Common - phage integrase family protein Oant_4340 100 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153010694 Common - glycosyl transferase group 1 Oant_3373 88 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153010106 Common - binding-protein-dependent transport systems inner membrane component Oant_2782 218 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011208 Common - binding-protein-dependent transport systems inner membrane component Oant_3888 215 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 153011155 Common - protein of unknown function DUF1612 Oant_3834 10 COG3177 COG3177, Uncharacterized conserved protein Function unknown 153011244 Common - AsmA family protein Oant_3924 26 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 153010888 Common - Monosaccharide-transporting ATPase Oant_3567 110 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153011192 Common - Amidohydrolase 3 Oant_3872 70 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 153011438 Common - phosphotransferase system lactose/cellobiose-specific IIB subunit Oant_4121 13 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 153011288 Common - extracellular solute-binding protein family 5 Oant_3968 201 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153010947 Common - bacterioferritin Oant_3626 111 COG2193 Bfr, Bacterioferritin (cytochrome b1) Inorganic ion transport and metabolism 153011030 Common - FAD dependent oxidoreductase Oant_3709 131 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153010829 Common - putative transcriptional regulator, GntR family Oant_3508 178 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153010915 Common - NMT1/THI5 like domain protein Oant_3594 37 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 153010920 Common - extracellular solute-binding protein family 5 Oant_3599 209 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 153010884 Common - transcriptional regulator, LysR family Oant_3563 135 COG0583 LysR, Transcriptional regulator Transcription 153010121 Common - Amidase Oant_2797 214 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 153011150 Pathogen - hypothetical protein Oant_3829 2 None None None 153011421 Pathogen - Pentapeptide MXKDX repeat protein Oant_4104 1 None None None 153010103 Common - transcriptional regulator, LysR family Oant_2779 149 COG0583 LysR, Transcriptional regulator Transcription 153010274 Common - short-chain dehydrogenase/reductase SDR Oant_2951 234 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 153011201 Common - Glutamate--ammonia ligase Oant_3881 223 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 153010941 Common - periplasmic binding protein Oant_3620 139 COG4558 ChuT, ABC-type hemin transport system, periplasmic component Inorganic ion transport and metabolism 153011399 Common - thiamine pyrophosphate protein central region Oant_4081 222 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 153010847 Common - transglutaminase domain protein Oant_3526 97 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 153010295 Common - cell division topological specificity factor MinE Oant_2972 74 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 153011140 Common - formate dehydrogenase family accessory protein FdhD Oant_3819 137 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 153010430 Common - acetyl-CoA acetyltransferase Oant_3107 178 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 153011618 Common - putative two-component response regulator protein Oant_4303 16 None None None 153010817 Common - extracellular solute-binding protein family 3 Oant_3496 184 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153010876 Common - Surfeit locus 1 family protein Oant_3555 59 COG3346 COG3346, Uncharacterized conserved protein Function unknown 153010435 Common - integral membrane sensor signal transduction histidine kinase Oant_3112 214 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 153010600 Common - Resolvase domain protein Oant_3278 58 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 153011187 Common - Endoribonuclease L-PSP Oant_3867 119 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153010812 Common - glycoside hydrolase family 25 Oant_3491 47 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 153010500 Common - hypothetical protein Oant_3177 13 None None None 153010408 Common - proline iminopeptidase Oant_3085 101 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153011222 Common - TRAP dicarboxylate transporter, DctP subunit Oant_3902 103 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 153010839 Common - amidohydrolase Oant_3518 88 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 153010682 Common - protein of unknown function DUF894 DitE Oant_3361 100 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010145 Common - dethiobiotin synthase Oant_2821 129 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 153011229 Common - putative simple sugar transport system substrate-binding protein Oant_3909 52 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010413 Common - binding-protein-dependent transport systems inner membrane component Oant_3090 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011217 Common - binding-protein-dependent transport systems inner membrane component Oant_3897 164 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153010981 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Oant_3660 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 153011369 Common - oxidoreductase FAD/NAD(P)-binding domain protein Oant_4051 159 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 153010938 Common - transcriptional regulator, BadM/Rrf2 family Oant_3617 100 COG1959 COG1959, Predicted transcriptional regulator Transcription 153010452 Common - ABC transporter related Oant_3129 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153011513 Common - OmpA/MotB domain protein Oant_4198 107 COG1360 MotB, Flagellar motor protein Cell motility and secretion 153011004 Common - phage integrase family protein Oant_3683 103 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153010562 Common - glutaredoxin Oant_3239 8 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 153011015 Pathogen - hypothetical protein Oant_3694 1 None None None 153010239 Common - transcriptional regulator, DeoR family Oant_2916 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 153010207 Common - Dual specificity protein phosphatase Oant_2884 22 COG2453 CDC14, Predicted protein-tyrosine phosphatase Signal transduction mechanisms 153010700 Common - glycosyl transferase, group 2 family protein Oant_3379 87 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153011295 Common - hypothetical protein Oant_3975 2 None None None 153010538 Common - AAA ATPase Oant_3215 63 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 153010972 Common - BA14K family protein Oant_3651 7 None None None 153011124 Common - binding-protein-dependent transport systems inner membrane component Oant_3803 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011332 Common - pyruvate ferredoxin/flavodoxin oxidoreductase Oant_4012 16 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 153010218 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Oant_2895 139 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 153010513 Common - protein of unknown function DUF736 Oant_3190 25 COG5489 COG5489, Uncharacterized conserved protein Function unknown 153010599 Common - hypothetical protein Oant_3277 3 None None None 153011550 Common - oxidoreductase domain protein Oant_4235 166 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153011439 Common - carboxyl-terminal protease Oant_4122 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 153011375 Common - Helix-turn-helix type 11 domain protein Oant_4057 16 None None None 153011465 Common - Dimethylmenaquinone methyltransferase Oant_4150 77 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 153010784 Common - Ectoine/hydroxyectoine ABC transporter permease protein EhuD Oant_3463 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153010534 Common - regulatory protein ArsR Oant_3211 52 COG0640 ArsR, Predicted transcriptional regulators Transcription 153010852 Common - monovalent cation/H+ antiporter, subunit 1 Oant_3531 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 153010764 Common - polysaccharide pyruvyl transferase Oant_3443 10 None None None 153010130 Common - peptidase S58 DmpA Oant_2806 47 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153011581 Common - Ferrochelatase Oant_4266 168 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 153011701 Common - cytochrome c class I Oant_4386 37 None None None 153010807 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_3486 45 COG3324 COG3324, Predicted enzyme related to lactoylglutathione lyase General function prediction only 153011748 Common - extracellular solute-binding protein family 1 Oant_4433 73 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 153010489 Common - hypothetical protein Oant_3166 9 None None None 153011109 Common - Amidohydrolase 3 Oant_3788 112 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 153011518 Common - flagellar biosynthetic protein FliP Oant_4203 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 153010995 Common - NUDIX hydrolase Oant_3674 37 None None None 153011485 Common - hypothetical protein Oant_4170 18 None None None 153010706 Common - aminotransferase class-III Oant_3385 235 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 153010086 Common - Alanine racemase Oant_2762 126 COG1609 PurR, Transcriptional regulators Transcription 153010314 Common - ABC transporter related Oant_2991 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153011060 Common - binding-protein-dependent transport systems inner membrane component Oant_3739 221 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011363 Common - ATP dependent DNA ligase Oant_4044 103 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 153011126 Common - ABC transporter related Oant_3805 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153010265 Common - binding-protein-dependent transport systems inner membrane component Oant_2942 179 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153010198 Common - oxidoreductase molybdopterin binding Oant_2875 26 COG3915 COG3915, Uncharacterized protein conserved in bacteria Function unknown 153010088 Common - polar amino acid ABC transporter, inner membrane subunit Oant_2764 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153011001 Common - GreA/GreB family elongation factor Oant_3680 79 COG0782 GreA, Transcription elongation factor Transcription 153011404 Common - regulatory protein IclR Oant_4086 64 COG1414 IclR, Transcriptional regulator Transcription 153010822 Common - phosphate acetyltransferase Oant_3501 156 COG0280 Pta, Phosphotransacetylase Energy production and conversion 153010795 Common - TonB-dependent siderophore receptor Oant_3474 121 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 153010965 Common - Nucleotidyl transferase Oant_3644 235 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 153011316 Common - monooxygenase FAD-binding Oant_3996 74 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 153011628 Common - hypothetical protein Oant_4313 44 COG3569 COG3569, Topoisomerase IB DNA replication, recombination, and repair 153011538 Common - hypothetical protein Oant_4223 9 None None None 153011615 Common - phage SPO1 DNA polymerase-related protein Oant_4300 149 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 153011511 Common - flagellar hook-length control protein Oant_4196 7 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 153011385 Common - periplasmic binding protein/LacI transcriptional regulator Oant_4067 106 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153011067 Common - extracellular solute-binding protein family 3 Oant_3746 178 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153010553 Common - 40-residue YVTN family beta-propeller repeat protein Oant_3230 96 COG3391 COG3391, Uncharacterized conserved protein Function unknown 153011147 Common - FAD dependent oxidoreductase Oant_3826 117 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153011055 Common - ABC transporter related Oant_3734 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153011423 Common - oxidoreductase molybdopterin binding Oant_4106 122 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 153011320 Common - inner-membrane translocator Oant_4000 147 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 153010667 Common - Monosaccharide-transporting ATPase Oant_3346 164 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153011309 Pathogen - hypothetical protein Oant_3989 2 None None None 153010283 Common - ABC transporter related Oant_2960 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153011594 Common - heat shock protein Hsp20 Oant_4279 68 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 153011411 Common - Alcohol dehydrogenase GroES domain protein Oant_4094 209 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 153010116 Common - aldehyde dehydrogenase Oant_2792 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153011601 Pathogen - hypothetical protein Oant_4286 1 None None None 153010361 Common - peptidase M16 domain protein Oant_3038 203 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 153010289 Common - hypothetical protein Oant_2966 45 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 153010712 Common - Glucose-1-phosphate cytidylyltransferase Oant_3391 147 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 153010203 Common - transcriptional regulator, LysR family Oant_2880 110 COG0583 LysR, Transcriptional regulator Transcription 153011304 Common - Pirin domain protein Oant_3984 146 COG1741 COG1741, Pirin-related protein General function prediction only 153010864 Common - cyd operon protein YbgT Oant_3543 11 COG4890 COG4890, Predicted outer membrane lipoprotein Function unknown 153010716 Common - transcriptional regulator, MarR family Oant_3395 64 COG1846 MarR, Transcriptional regulators Transcription 153010147 Common - biotin synthase Oant_2823 186 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 153011708 Common - monooxygenase FAD-binding Oant_4393 74 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 153010465 Common - ATPase involved in DNA repair-like protein Oant_3142 26 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 153011287 Common - binding-protein-dependent transport systems inner membrane component Oant_3967 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010620 Common - Citrate (pro-3S)-lyase Oant_3299 111 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 153010271 Common - cytochrome c class I Oant_2948 57 COG3474 COG3474, Cytochrome c2 Energy production and conversion 153011085 Common - TRAP dicarboxylate transporter, DctM subunit Oant_3764 127 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 153011689 Common - Cystathionine gamma-synthase Oant_4374 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 153011739 Common - branched-chain amino acid ABC transporter, periplasmic substrate-binding protein Oant_4424 123 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 153010636 Common - L-2-amino-thiazoline-4-carboxylic acid hydrolase Oant_3315 8 None None None 153010249 Common - ABC transporter related Oant_2926 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153010766 Pathogen - hypothetical protein Oant_3445 1 None None None 153010890 Common - ABC transporter related Oant_3569 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153010649 Common - protein of unknown function DUF808 Oant_3328 60 COG2354 COG2354, Uncharacterized protein conserved in bacteria Function unknown 153011583 Common - protein of unknown function DUF107 Oant_4268 42 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153010498 Common - hypothetical protein Oant_3175 37 None None None 153010640 Common - binding-protein-dependent transport systems inner membrane component Oant_3319 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010185 Common - molybdopterin oxidoreductase Fe4S4 region Oant_2862 168 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 153010842 Common - ABC transporter related Oant_3521 249 COG4598 HisP, ABC-type histidine transport system, ATPase component Amino acid transport and metabolism 153010242 Common - Cupin 2 conserved barrel domain protein Oant_2919 67 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 153011359 Common - hypothetical protein Oant_4040 28 None None None 153010392 Common - drug resistance transporter, EmrB/QacA subfamily Oant_3069 213 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010558 Common - multicopper oxidase type 2 Oant_3235 107 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 153010387 Common - periplasmic binding protein/LacI transcriptional regulator Oant_3064 94 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153011496 Common - hypothetical protein Oant_4181 11 None None None 153011752 Common - binding-protein-dependent transport systems inner membrane component Oant_4437 227 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153010450 Common - binding-protein-dependent transport systems inner membrane component Oant_3127 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010151 Common - periplasmic binding protein Oant_2827 55 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153010234 Common - carbohydrate kinase FGGY Oant_2911 134 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 153011236 Common - periplasmic binding protein Oant_3916 80 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153011013 Pathogen - hypothetical protein Oant_3692 1 None None None 153010352 Common - HAD-superfamily hydrolase, subfamily IIA Oant_3029 87 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 153011166 Common - delta-1-pyrroline-5-carboxylate dehydrogenase Oant_3846 220 COG4230 COG4230, Delta 1-pyrroline-5-carboxylate dehydrogenase Energy production and conversion 153011134 Common - major facilitator superfamily MFS_1 Oant_3813 183 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010750 Common - glycosyl transferase group 1 Oant_3429 161 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153011398 Common - transcriptional regulator, LysR family Oant_4080 185 COG0583 LysR, Transcriptional regulator Transcription 153011441 Pathogen - hypothetical protein Oant_4124 1 None None None 153010571 Common - DSBA oxidoreductase Oant_3248 85 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 153010125 Common - transcriptional regulator, RpiR family Oant_2801 52 COG1737 RpiR, Transcriptional regulators Transcription 153010098 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Oant_2774 142 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153010443 Common - peptidase M24 Oant_3120 245 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 153011724 Common - helix-turn-helix- domain containing protein AraC type Oant_4409 64 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153010597 Common - hypothetical protein Oant_3275 7 None None None 153011075 Common - TrkA-C domain protein Oant_3754 102 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 153010612 Common - transcriptional regulator, MarR family Oant_3291 127 COG1846 MarR, Transcriptional regulators Transcription 153010468 Common - hypothetical protein Oant_3145 23 COG4544 COG4544, Uncharacterized conserved protein Function unknown 153010728 Common - Monosaccharide-transporting ATPase Oant_3407 161 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153010779 Common - Xylose isomerase domain protein TIM barrel Oant_3458 34 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 153011092 Common - protein of unknown function DUF1127 Oant_3771 3 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 153011111 Common - binding-protein-dependent transport systems inner membrane component Oant_3790 170 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 153010672 Common - Domain of unknown function DUF1801 Oant_3351 13 COG5649 COG5649, Uncharacterized conserved protein Function unknown 153010158 Common - Lipocalin family protein Oant_2835 68 COG3040 Blc, Bacterial lipocalin Cell envelope biogenesis, outer membrane 153011218 Common - putative endoribonuclease L-PSP Oant_3898 194 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153010815 Common - putative transcriptional regulator, AsnC family Oant_3494 86 COG1522 Lrp, Transcriptional regulators Transcription 153011335 Common - short-chain dehydrogenase/reductase SDR Oant_4015 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153011548 Common - 6-phosphogluconate dehydrogenase, decarboxylating Oant_4233 181 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 153010230 Common - transcriptional regulator, DeoR family Oant_2907 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 153011770 Common - parB-like partition protein Oant_4455 60 COG1475 Spo0J, Predicted transcriptional regulators Transcription 153011358 Common - protein of unknown function DUF81 Oant_4039 38 COG0730 COG0730, Predicted permeases General function prediction only 153010775 Common - extracellular solute-binding protein family 1 Oant_3454 74 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010952 Common - inner-membrane translocator Oant_3631 105 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 153011250 Common - isocitrate lyase Oant_3930 128 COG2224 AceA, Isocitrate lyase Energy production and conversion 153010529 Common - protein of unknown function DUF461 Oant_3206 82 COG2847 COG2847, Uncharacterized protein conserved in bacteria Function unknown 153010356 Common - hypothetical protein Oant_3033 10 None None None 153011256 Common - Glutamate--putrescine ligase Oant_3936 225 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 153011046 Common - 3-oxoadipate enol-lactonase Oant_3725 171 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153011035 Common - binding-protein-dependent transport systems inner membrane component Oant_3714 209 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153010933 Common - CrcB protein Oant_3612 186 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 153011081 Common - 2-hydroxy-3-oxopropionate reductase Oant_3760 181 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 153010749 Common - hypothetical protein Oant_3428 12 COG2327 WcaK, Uncharacterized conserved protein Function unknown 153010241 Common - FAD dependent oxidoreductase Oant_2918 155 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 153011088 Common - CMP/dCMP deaminase zinc-binding Oant_3767 17 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 153011260 Common - hypothetical protein Oant_3940 16 None None None 153010171 Common - extracellular solute-binding protein family 3 Oant_2848 185 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153010248 Common - secretion protein HlyD family protein Oant_2925 142 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 153011647 Common - hypothetical protein Oant_4332 4 None None None 153011330 Common - transcriptional regulator, MarR family Oant_4010 79 COG1846 MarR, Transcriptional regulators Transcription 153011433 Common - Transketolase central region Oant_4116 197 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 153010850 Common - hypothetical protein Oant_3529 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 153010254 Common - ABC transporter related Oant_2931 248 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 153010532 Common - putative transcriptional regulator, MerR family Oant_3209 149 COG0789 SoxR, Predicted transcriptional regulators Transcription 153011477 Common - protein tyrosine phosphatase Oant_4162 16 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 153010483 Common - mercuric reductase Oant_3160 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 153010192 Common - selenocysteine-specific translation elongation factor Oant_2869 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 153010110 Common - Hemolysin-type calcium-binding region Oant_2786 68 None None None 153011473 Common - hypothetical protein Oant_4158 8 None None None 153011665 Common - extracellular solute-binding protein family 3 Oant_4350 147 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153011663 Common - DSBA oxidoreductase Oant_4348 45 COG3917 NahD, 2-hydroxychromene-2-carboxylate isomerase Secondary metabolites biosynthesis, transport, and catabolism 153010209 Common - phospholipid/glycerol acyltransferase Oant_2886 48 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 153011237 Common - Uncharacterized protein UPF0065 Oant_3917 72 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 153010837 Common - two component transcriptional regulator, winged helix family Oant_3516 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153010786 Common - Ectoine/hydroxyEctoine ABC transporter solute-binding protein Oant_3465 91 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153011354 Common - protein of unknown function DUF1236 Oant_4035 6 None None None 153010789 Common - Ectoine utilization protein EutC Oant_3468 92 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 153010814 Common - hypothetical protein Oant_3493 27 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 153011123 Common - binding-protein-dependent transport systems inner membrane component Oant_3802 221 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011414 Common - hypothetical protein Oant_4097 8 None None None 153010780 Common - oxidoreductase domain protein Oant_3459 155 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153010511 Common - hypothetical protein Oant_3188 23 None None None 153011002 Common - DNA-directed DNA polymerase Oant_3681 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 153010563 Common - heavy metal translocating P-type ATPase Oant_3240 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 153010164 Common - Monosaccharide-transporting ATPase Oant_2841 112 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153011754 Common - ABC transporter related Oant_4439 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153011037 Common - spermidine/putrescine ABC transporter ATPase subunit Oant_3716 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153011486 Pathogen - hypothetical protein Oant_4171 2 COG0583 LysR, Transcriptional regulator Transcription 153011290 Common - hypothetical protein Oant_3970 15 None None None 153010924 Common - diguanylate cyclase Oant_3603 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153010432 Common - AMP-dependent synthetase and ligase Oant_3109 222 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 153010953 Common - ABC transporter related Oant_3632 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 153010104 Common - hypothetical protein Oant_2780 6 None None None 153010866 Common - ATPase BadF/BadG/BcrA/BcrD type Oant_3545 58 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 153011023 Common - ABC transporter related Oant_3702 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153010601 Common - hypothetical protein Oant_3279 2 None None None 153010999 Common - response regulator receiver protein Oant_3678 224 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 153010233 Common - FAD dependent oxidoreductase Oant_2910 147 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 153011053 Common - inner-membrane translocator Oant_3732 85 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 153011714 Common - inner-membrane translocator Oant_4399 149 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 153010608 Common - 3-isopropylmalate dehydrogenase Oant_3287 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 153011514 Common - hypothetical protein Oant_4199 6 None None None 153011436 Common - PTS system Galactitol-specific IIC component Oant_4119 19 COG3775 GatC, Phosphotransferase system, galactitol-specific IIC component Carbohydrate transport and metabolism 153010616 Common - Lysine exporter protein (LYSE/YGGA) Oant_3295 117 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 153011210 Common - hypothetical protein Oant_3890 7 None None None 153010922 Common - binding-protein-dependent transport systems inner membrane component Oant_3601 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010409 Common - peptidase S9 prolyl oligopeptidase active site domain protein Oant_3086 149 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 153011541 Common - secretion protein HlyD family protein Oant_4226 173 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 153010932 Common - protein of unknown function DUF861 cupin_3 Oant_3611 24 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 153010516 Common - TRAG family protein Oant_3193 79 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 153011469 Common - binding-protein-dependent transport systems inner membrane component Oant_4154 144 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 153010282 Common - ABC transporter related Oant_2959 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010918 Common - porin Oant_3597 13 None None None 153010334 Common - FAD linked oxidase domain protein Oant_3011 160 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 153011494 Common - putative ferric uptake regulator, Fur family Oant_4179 94 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 153010304 Common - transcriptional regulator, RpiR family Oant_2981 78 COG1737 RpiR, Transcriptional regulators Transcription 153010945 Common - Antibiotic biosynthesis monooxygenase Oant_3624 39 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 153011559 Common - GCN5-related N-acetyltransferase Oant_4244 52 COG3153 COG3153, Predicted acetyltransferase General function prediction only 153010698 Pathogen - hypothetical protein Oant_3377 3 None None None 153010266 Common - ABC transporter related Oant_2943 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153011205 Pathogen - hypothetical protein Oant_3885 1 None None None 153011189 Common - Creatininase Oant_3869 84 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 153011203 Common - iron-containing alcohol dehydrogenase Oant_3883 172 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 153011452 Common - periplasmic binding protein Oant_4137 88 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153011616 Common - hypothetical protein Oant_4301 3 None None None 153010119 Common - hypothetical protein Oant_2795 26 COG3665 COG3665, Uncharacterized conserved protein Function unknown 153010760 Common - glycosyl transferase group 1 Oant_3439 137 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153011271 Common - transcriptional regulator, LysR family Oant_3951 178 COG0583 LysR, Transcriptional regulator Transcription 153010882 Common - peptidase S58 DmpA Oant_3561 50 COG3191 DmpA, L-aminopeptidase/D-esterase Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153010983 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Oant_3662 159 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 153010911 Common - binding-protein-dependent transport systems inner membrane component Oant_3590 179 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153011532 Common - chemotaxis motA protein Oant_4217 109 COG1291 MotA, Flagellar motor component Cell motility and secretion 153010547 Pathogen - hypothetical protein Oant_3224 1 None None None 153010858 Pathogen - hypothetical protein Oant_3537 2 None None None 153011282 Common - hypothetical protein Oant_3962 7 None None None 153010560 Common - putative transcriptional regulator, MerR family Oant_3237 117 COG0789 SoxR, Predicted transcriptional regulators Transcription 153010739 Common - hypothetical protein Oant_3418 2 None None None 153011219 Common - uncharacterised conserved protein UCP012702 Oant_3899 32 COG5476 COG5476, Uncharacterized conserved protein Function unknown 153011503 Common - flagellar hook capping protein Oant_4188 105 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 153010913 Common - binding-protein-dependent transport systems inner membrane component Oant_3592 195 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153010802 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Oant_3481 168 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 153010329 Common - metallophosphoesterase Oant_3006 68 None None None 153010429 Common - acyl-CoA dehydrogenase domain protein Oant_3106 165 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153010508 Common - Cobyrinic acid ac-diamide synthase Oant_3185 201 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 153011566 Common - GCN5-related N-acetyltransferase Oant_4251 94 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153010759 Common - transcriptional regulator, MarR family Oant_3438 23 COG1846 MarR, Transcriptional regulators Transcription 153011176 Common - protein of unknown function DUF451 Oant_3856 28 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 153010959 Common - extracellular solute-binding protein family 5 Oant_3638 175 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 153010278 Common - Ribonucleoside-diphosphate reductase Oant_2955 148 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 153011113 Common - lipoprotein, YaeC family Oant_3792 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 153010903 Common - Alcohol dehydrogenase GroES domain protein Oant_3582 202 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 153010445 Common - transcriptional regulator, RpiR family Oant_3122 123 COG1737 RpiR, Transcriptional regulators Transcription 153010592 Pathogen - hypothetical protein Oant_3269 1 None None None 153011492 Common - ABC transporter related Oant_4177 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 153010720 Common - Asparaginase/glutaminase Oant_3399 137 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 153010522 Common - arsenate reductase Oant_3199 106 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 153011097 Common - potassium-transporting ATPase, A subunit Oant_3776 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 153010461 Common - GCN5-related N-acetyltransferase Oant_3138 47 COG0456 RimI, Acetyltransferases General function prediction only 153010350 Common - chaperonin Cpn10 Oant_3027 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 153011562 Common - transcriptional regulator, LysR family Oant_4247 168 COG0583 LysR, Transcriptional regulator Transcription 153011520 Common - flagellar L-ring protein Oant_4205 95 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 153010659 Common - ABC transporter related Oant_3338 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153010629 Common - ABC transporter related Oant_3308 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 153010152 Common - Transposase and inactivated derivatives-like protein Oant_2829 47 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 153011255 Common - hypothetical protein Oant_3935 4 None None None 153010755 Common - glycosyl transferase family 2 Oant_3434 100 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 153011763 Common - conserved hypothetical signal peptide protein Oant_4448 28 COG4222 COG4222, Uncharacterized protein conserved in bacteria Function unknown 153011280 Common - lipopolysaccharide biosynthesis protein Oant_3960 6 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 153010689 Common - two component transcriptional regulator, LuxR family Oant_3368 150 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 153010235 Common - hypothetical protein Oant_2912 7 COG5618 COG5618, Predicted periplasmic lipoprotein General function prediction only 153010950 Common - basic membrane lipoprotein Oant_3629 94 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 153011670 Pathogen - hypothetical protein Oant_4355 1 None None None 153010219 Common - hypothetical protein Oant_2896 19 None None None 153011289 Common - hypothetical protein Oant_3969 4 None None None 153010354 Common - MltA-interacting MipA family protein Oant_3031 25 COG3713 OmpV, Outer membrane protein V Cell envelope biogenesis, outer membrane 153011327 Common - NADPH-dependent FMN reductase Oant_4007 50 COG0431 COG0431, Predicted flavoprotein General function prediction only 153010804 Common - aminotransferase class I and II Oant_3483 147 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153011608 Common - hypothetical protein Oant_4293 15 None None None 153011444 Common - integral membrane sensor signal transduction histidine kinase Oant_4127 217 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 153010642 Common - short-chain dehydrogenase/reductase SDR Oant_3321 227 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 153011527 Common - flagellar basal-body rod protein FlgB Oant_4212 12 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 153010491 Common - hypothetical protein Oant_3168 4 None None None 153011393 Common - ABC transporter related Oant_4075 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153011577 Common - 4-amino-4-deoxychorismate lyase Oant_4262 68 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 153010582 Common - Siderophore transporter RhtX/FptX family Oant_3259 104 None None None 153011220 Common - TRAP dicarboxylate transporter, DctM subunit Oant_3900 142 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 153011621 Common - putative transcriptional regulator, Crp/Fnr family Oant_4306 28 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153010611 Common - aspartate-semialdehyde dehydrogenase Oant_3290 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 153010702 Common - polysaccharide biosynthesis protein Oant_3381 79 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 153011322 Common - ABC transporter related Oant_4002 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153010934 Common - transcriptional regulator, LysR family Oant_3613 127 COG0583 LysR, Transcriptional regulator Transcription 153010840 Common - polar amino acid ABC transporter, inner membrane subunit Oant_3519 171 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 153011381 Common - periplasmic binding protein/LacI transcriptional regulator Oant_4063 82 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010997 Common - ribosomal protein L33 Oant_3676 123 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 153011094 Common - aminotransferase class IV Oant_3773 193 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 153011458 Common - protein of unknown function DUF1634 Oant_4143 13 COG4272 COG4272, Predicted membrane protein Function unknown 153011742 Common - transcriptional regulator, TetR family Oant_4427 118 COG1309 AcrR, Transcriptional regulator Transcription 153010551 Common - Heavy metal transport/detoxification protein Oant_3228 18 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 153010313 Common - pyridoxal phosphate-dependent enzyme, putative Oant_2990 75 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 153010650 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_3329 40 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 153011352 Common - acyl-CoA dehydrogenase domain protein Oant_4033 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153010134 Common - outer membrane autotransporter barrel domain protein Oant_2810 148 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 153011073 Common - binding-protein-dependent transport systems inner membrane component Oant_3752 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153010479 Common - putative transcriptional regulator, MerR family Oant_3156 142 COG0789 SoxR, Predicted transcriptional regulators Transcription 153010639 Common - binding-protein-dependent transport systems inner membrane component Oant_3318 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011231 Common - inner-membrane translocator Oant_3911 93 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153011143 Common - diguanylate cyclase/phosphodiesterase Oant_3822 178 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 153011683 Common - Glycerone kinase Oant_4368 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 153010798 Common - Glutathione S-transferase domain protein Oant_3477 59 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153010765 Common - putative protein, probably exported to periplasma Oant_3444 2 None None None 153010363 Common - Patatin Oant_3040 106 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 153011314 Pathogen - LrgA family protein Oant_3994 1 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 153010630 Common - Amidase Oant_3309 203 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 153011044 Common - 4-hydroxybenzoate 3-monooxygenase Oant_3723 64 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 153011429 Common - phosphoenolpyruvate-protein phosphotransferase Oant_4112 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 153010437 Common - putative transcriptional regulator, Crp/Fnr family Oant_3114 168 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153010577 Common - L-lysine 6-monooxygenase (NADPH) Oant_3254 53 COG3486 IucD, Lysine/ornithine N-monooxygenase Secondary metabolites biosynthesis, transport, and catabolism 153011599 Common - response regulator receiver protein Oant_4284 218 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 153011733 Common - transcriptional regulator, GntR family Oant_4418 134 COG1802 GntR, Transcriptional regulators Transcription 153010908 Common - transmembrane pair domain protein Oant_3587 41 COG4125 COG4125, Predicted membrane protein Function unknown 153011401 Common - transport system permease protein Oant_4083 184 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153010221 Common - dihydrodipicolinate synthetase Oant_2898 130 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 153011086 Common - TRAP dicarboxylate transporter, DctP subunit Oant_3765 104 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 153010384 Common - Monosaccharide-transporting ATPase Oant_3061 115 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153010131 Common - Monosaccharide-transporting ATPase Oant_2807 121 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010210 Common - phosphatidate cytidylyltransferase Oant_2887 214 COG4589 COG4589, Predicted CDP-diglyceride synthetase/phosphatidate cytidylyltransferase General function prediction only 153010091 Common - outer membrane autotransporter barrel domain protein Oant_2767 70 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 153010792 Common - aldehyde dehydrogenase Oant_3471 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153010367 Common - hypothetical protein Oant_3044 24 None None None 153010984 Common - beta-lactamase domain protein Oant_3663 88 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 153011299 Common - binding-protein-dependent transport systems inner membrane component Oant_3979 152 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153011238 Common - putative tricarboxylic transport membrane protein Oant_3918 10 None None None 153010734 Common - regulatory protein LacI Oant_3413 104 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010661 Common - binding-protein-dependent transport systems inner membrane component Oant_3340 204 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153010176 Common - aminotransferase class-III Oant_2853 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 153010260 Common - transcriptional regulator, GntR family Oant_2937 135 COG1802 GntR, Transcriptional regulators Transcription 153011380 Common - ABC transporter related Oant_4062 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153011765 Pathogen - hypothetical protein Oant_4450 1 None None None 153011007 Pathogen - hypothetical protein Oant_3686 1 None None None 153010378 Common - Fmu (Sun) domain protein Oant_3055 206 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 153010344 Common - DoxX family protein Oant_3021 75 COG2259 COG2259, Predicted membrane protein Function unknown 153011480 Common - transcriptional regulator, TetR family Oant_4165 85 COG1309 AcrR, Transcriptional regulator Transcription 153010705 Common - glycosyl transferase group 1 Oant_3384 209 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153011409 Common - Tripartite ATP-independent periplasmic transporter DctQ component Oant_4092 15 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 153010080 Common - hypothetical protein Oant_2755 9 COG4026 COG4026, Uncharacterized protein containing TOPRIM domain, potential nuclease General function prediction only 153011693 Common - protein of unknown function DUF59 Oant_4378 156 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 153010696 Common - glycosyl transferase group 1 Oant_3375 206 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153011106 Common - binding-protein-dependent transport systems inner membrane component Oant_3785 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010824 Common - FAD dependent oxidoreductase Oant_3503 107 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153011065 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Oant_3744 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 153011365 Common - 2-nitropropane dioxygenase NPD Oant_4046 80 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 153010471 Pathogen - hypothetical protein Oant_3148 1 None None None 153011635 Common - hypothetical protein Oant_4320 2 None None None 153011364 Common - hypothetical protein Oant_4045 6 None None None 153010348 Common - transcriptional regulator, HxlR family Oant_3025 146 COG1733 COG1733, Predicted transcriptional regulators Transcription 153011387 Common - Glycerone kinase Oant_4069 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 153010873 Common - Transketolase central region Oant_3552 197 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 153010894 Common - L-rhamnose catabolism isomerase Oant_3573 31 COG4952 COG4952, Predicted sugar isomerase Cell envelope biogenesis, outer membrane 153011461 Common - NUDIX hydrolase Oant_4146 135 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 153010962 Common - protein of unknown function DUF339 Oant_3641 38 COG2938 COG2938, Uncharacterized conserved protein Function unknown 153011000 Common - hypothetical protein Oant_3679 12 None None None 153010566 Common - protein of unknown function DUF156 Oant_3243 89 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 153011226 Common - Mannitol dehydrogenase domain protein Oant_3906 87 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 153011020 Common - ABC transporter related Oant_3699 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 153011269 Common - alkylhydroperoxidase like protein, AhpD family Oant_3949 77 COG2128 COG2128, Uncharacterized conserved protein Function unknown 153011277 Common - 6-phosphogluconolactonase Oant_3957 119 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 153011121 Common - ABC transporter related Oant_3800 249 COG4604 CeuD, ABC-type enterochelin transport system, ATPase component Inorganic ion transport and metabolism 153010782 Common - putative transcriptional regulator, GntR family Oant_3461 191 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153010473 Common - hypothetical protein Oant_3150 19 None None None 153011372 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Oant_4054 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 153010322 Common - protein of unknown function DUF558 Oant_2999 168 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 153011560 Common - Orn/DAP/Arg decarboxylase 2 Oant_4245 217 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 153011292 Common - two component transcriptional regulator, LuxR family Oant_3972 143 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 153010860 Common - ABC transporter CydDC cysteine exporter (CydDC-E) family permease/ATP-binding protein CydD Oant_3539 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 153011756 Common - basic membrane lipoprotein Oant_4441 105 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 153011431 Common - transcriptional regulator, DeoR family Oant_4114 67 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 153010520 Common - Arsenate resistance ArsH Oant_3197 65 COG0431 COG0431, Predicted flavoprotein General function prediction only 153010637 Common - FAD dependent oxidoreductase Oant_3316 103 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153011128 Common - 5-oxoprolinase (ATP-hydrolyzing) Oant_3807 117 COG0146 HyuB, N-methylhydantoinase B/acetone carboxylase, alpha subunit Amino acid transport and metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153011379 Common - Monosaccharide-transporting ATPase Oant_4061 110 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153011082 Common - Mandelate racemase/muconate lactonizing protein Oant_3761 106 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 153011032 Common - extracellular solute-binding protein family 3 Oant_3711 181 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153010747 Common - HPP family protein? Oant_3426 69 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 153011471 Common - extracellular solute-binding protein family 1 Oant_4156 79 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 153010448 Common - glucokinase regulatory-like protein Oant_3125 83 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 153010194 Common - Isoprenylcysteine carboxyl methyltransferase Oant_2871 51 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 153010160 Common - deoxyribose-phosphate aldolase Oant_2837 132 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 153011516 Common - flagellin domain protein Oant_4201 80 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 153011079 Common - FAD linked oxidase domain protein Oant_3758 200 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 153010898 Common - ABC transporter related Oant_3577 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 153011355 Common - putative transcriptional regulator, MerR family Oant_4036 41 COG0789 SoxR, Predicted transcriptional regulators Transcription 153010247 Common - transcriptional regulator, TetR family Oant_2924 50 COG1309 AcrR, Transcriptional regulator Transcription 153011467 Common - HpcH/HpaI aldolase Oant_4152 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 153011585 Common - hypothetical protein Oant_4270 17 COG5338 COG5338, Uncharacterized protein conserved in bacteria Function unknown 153010464 Common - metallophosphoesterase Oant_3141 52 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 153010768 Common - alpha-2-macroglobulin domain protein Oant_3447 80 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 153010626 Common - hypothetical protein Oant_3305 11 None None None 153010691 Common - polysaccharide export protein Oant_3370 102 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 153010986 Common - acyl-CoA dehydrogenase domain protein Oant_3665 148 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153010710 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Oant_3389 165 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 153011645 Common - hypothetical protein Oant_4330 2 COG3152 COG3152, Predicted membrane protein Function unknown 153010732 Common - xylose isomerase Oant_3411 72 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 153010485 Common - hypothetical protein Oant_3162 14 None None None 153010214 Common - nitrate reductase, alpha subunit Oant_2891 96 COG5013 NarG, Nitrate reductase alpha subunit Energy production and conversion 153010223 Common - pseudoazurin Oant_2900 26 COG3794 PetE, Plastocyanin Energy production and conversion 153011575 Common - oligoendopeptidase, pepF/M3 family Oant_4260 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 153010410 Common - amidohydrolase Oant_3087 85 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 153010969 Common - putative iron-regulated membrane protein Oant_3648 66 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 153010971 Common - band 7 protein Oant_3650 168 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 153011011 Common - hypothetical protein Oant_3690 2 None None None 153011475 Common - putative transcriptional regulator, AsnC family Oant_4160 152 COG1522 Lrp, Transcriptional regulators Transcription 153010530 Common - Co/Zn/Cd efflux system component Oant_3207 76 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 153011184 Common - glycine cleavage system T protein Oant_3864 178 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 153011262 Common - protein of unknown function DUF156 Oant_3942 100 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 153011207 Common - Substrate-binding region of ABC-type glycine betaine transport system Oant_3887 89 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 153011171 Common - ABC transporter related Oant_3851 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153011672 Common - flavin reductase domain protein FMN-binding Oant_4357 103 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 153011243 Common - PAS/PAC sensor signal transduction histidine kinase Oant_3923 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153011278 Common - 6-phosphogluconate dehydratase Oant_3958 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 153011136 Common - binding-protein-dependent transport systems inner membrane component Oant_3815 165 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153010370 Common - tetraacyldisaccharide 4'-kinase Oant_3047 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 153010291 Common - aminotransferase class-III Oant_2968 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 153010327 Common - glutamine amidotransferase class-I Oant_3004 114 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 153011557 Common - hypothetical protein Oant_4242 7 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 153010587 Common - FAD dependent oxidoreductase Oant_3264 94 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153010298 Common - Lysine exporter protein (LYSE/YGGA) Oant_2975 79 COG1279 COG1279, Lysine efflux permease General function prediction only 153010401 Common - deoxyribose-phosphate aldolase/phospho-2-dehydro-3-deoxyheptonate aldolase Oant_3078 66 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 153010395 Common - putative ABC transporter periplasmic sugar-binding protein Oant_3072 96 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010737 Common - Monosaccharide-transporting ATPase Oant_3416 107 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 153010800 Common - integral membrane sensor signal transduction histidine kinase Oant_3479 223 COG4191 COG4191, Signal transduction histidine kinase regulating C4-dicarboxylate transport system Signal transduction mechanisms 153011534 Pathogen - hypothetical protein Oant_4219 3 None None None 153010481 Common - Heavy metal transport/detoxification protein Oant_3158 60 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 153010182 Common - uracil-xanthine permease Oant_2859 123 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 153010427 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Oant_3104 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 153011522 Common - flagellar P-ring protein Oant_4207 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 153010549 Common - cation diffusion facilitator family transporter Oant_3226 180 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 153011685 Common - ABC transporter related Oant_4370 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153010926 Common - Alcohol dehydrogenase zinc-binding domain protein Oant_3605 152 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 153010526 Common - lipoprotein signal peptidase Oant_3203 164 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 153010112 Common - extracellular solute-binding protein family 1 Oant_2788 117 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 153010136 Common - periplasmic binding protein/LacI transcriptional regulator Oant_2812 68 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 153010879 Common - ABC transporter related Oant_3558 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153010149 Common - transport system permease protein Oant_2825 187 COG4779 FepG, ABC-type enterobactin transport system, permease component Inorganic ion transport and metabolism 153011191 Common - binding-protein-dependent transport systems inner membrane component Oant_3871 180 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153010202 Common - Alpha/beta hydrolase fold-3 domain protein Oant_2879 77 COG0657 Aes, Esterase/lipase Lipid metabolism 153010742 Common - protein of unknown function DUF112 transmembrane Oant_3421 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 153011416 Common - Domain of unknown function DUF1850 Oant_4099 12 COG4729 COG4729, Uncharacterized conserved protein Function unknown 153011571 Common - hypothetical protein Oant_4256 18 None None None 153011025 Common - binding-protein-dependent transport systems inner membrane component Oant_3704 188 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 153011168 Common - Mannitol dehydrogenase domain protein Oant_3848 90 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 153010514 Common - Lytic transglycosylase catalytic Oant_3191 158 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 153010109 Common - peptidase S15 Oant_2785 69 COG2936 COG2936, Predicted acyl esterases General function prediction only 153011178 Common - protein of unknown function DUF451 Oant_3858 27 COG2822 COG2822, Predicted periplasmic lipoprotein involved in iron transport Inorganic ion transport and metabolism 153011212 Common - transcriptional regulator, RpiR family Oant_3892 88 COG1737 RpiR, Transcriptional regulators Transcription 153011151 Common - major facilitator superfamily MFS_1 Oant_3830 136 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 153011589 Common - protein of unknown function DUF459 Oant_4274 28 COG2845 COG2845, Uncharacterized protein conserved in bacteria Function unknown 153010439 Common - peptidase U32 Oant_3116 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 153011103 Common - aldehyde dehydrogenase Oant_3782 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153011630 Common - DNA ligase D Oant_4315 111 COG3285 COG3285, Predicted eukaryotic-type DNA primase DNA replication, recombination, and repair 153010835 Common - binding-protein-dependent transport systems inner membrane component Oant_3514 152 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153011440 Pathogen - hypothetical protein Oant_4123 1 None None None 153010169 Common - major facilitator superfamily MFS_1 Oant_2846 41 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010175 Common - hypothetical protein Oant_2852 20 None None None 153010518 Pathogen - hypothetical protein Oant_3195 1 None None None 153011679 Common - MlrC domain protein Oant_4364 32 COG5476 COG5476, Uncharacterized conserved protein Function unknown 153011198 Common - Tripartite ATP-independent periplasmic transporter DctQ component Oant_3878 26 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 153010142 Common - FAD dependent oxidoreductase Oant_2818 79 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153010867 Common - extracellular solute-binding protein family 1 Oant_3546 70 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010607 Common - protein of unknown function DUF343 Oant_3286 93 COG2835 COG2835, Uncharacterized conserved protein Function unknown 153010434 Common - General substrate transporter Oant_3111 135 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153011131 Common - ABC transporter related Oant_3810 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153010846 Common - protein of unknown function DUF403 Oant_3525 82 COG2307 COG2307, Uncharacterized protein conserved in bacteria Function unknown 153011018 Common - hypothetical protein Oant_3697 45 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 153010493 Common - hypothetical protein Oant_3170 7 None None None 153010129 Common - Ornithine carbamoyltransferase Oant_2805 207 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153010957 Common - hemimethylated DNA binding protein Oant_3636 43 COG3785 COG3785, Uncharacterized conserved protein Function unknown 153010180 Common - thioesterase superfamily protein Oant_2857 9 COG0824 FcbC, Predicted thioesterase General function prediction only 153010200 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Oant_2877 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 153011153 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Oant_3832 206 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 153011418 Common - TRAP transporter solute receptor, TAXI family Oant_4101 87 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 153010225 Common - transketolase Oant_2902 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 153011623 Pathogen - hypothetical protein Oant_4308 1 None None None 153010584 Common - helix-turn-helix- domain containing protein AraC type Oant_3261 76 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153011597 Common - histidinol-phosphate phosphatase, putative Oant_4282 181 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 153011529 Common - ATPase, FliI/YscN family Oant_4214 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 153011573 Common - protein of unknown function DUF882 Oant_4258 61 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 153011042 Common - beta-ketoadipate pathway transcriptional regulators, PcaR/PcaU/PobR family Oant_3721 119 COG1414 IclR, Transcriptional regulator Transcription 153011456 Common - pyridoxal kinase Oant_4141 103 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 153010572 Common - Thiol:disulfide interchange protein-like protein Oant_3249 52 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 153010880 Common - efflux transporter, RND family, MFP subunit Oant_3559 171 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 153011446 Common - hypothetical protein Oant_4131 9 None None None 153011383 Common - ABC transporter related Oant_4065 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153010828 Common - taurine ABC transporter, periplasmic binding protein Oant_3507 87 COG4521 TauA, ABC-type taurine transport system, periplasmic component Inorganic ion transport and metabolism 153010618 Common - 3-isopropylmalate dehydratase, small subunit Oant_3297 211 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 153011090 Common - hypothetical protein Oant_3769 17 None None None 153011040 Common - 3-oxoacid CoA-transferase, B subunit Oant_3719 91 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 153011248 Common - extracellular solute-binding protein family 1 Oant_3928 129 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 153010901 Common - binding-protein-dependent transport systems inner membrane component Oant_3580 205 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 153011716 Common - extracellular ligand-binding receptor Oant_4401 136 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 153011505 Common - flagellar FlaF family protein Oant_4190 14 COG5442 FlaF, Flagellar biosynthesis regulator FlaF Cell motility and secretion 153010154 Common - Cupin 2 conserved barrel domain protein Oant_2831 12 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 153011138 Common - extracellular solute-binding protein family 1 Oant_3817 64 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153011761 Common - Inosine/uridine-preferring nucleoside hydrolase Oant_4446 89 COG1957 URH1, Inosine-uridine nucleoside N-ribohydrolase Nucleotide transport and metabolism 153010575 Common - two component transcriptional regulator, winged helix family Oant_3252 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153010320 Common - ErfK/YbiS/YcfS/YnhG family protein Oant_2997 77 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153010397 Common - Monosaccharide-transporting ATPase Oant_3074 115 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153011721 Common - peptidase T Oant_4406 62 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 153010771 Common - GCN5-related N-acetyltransferase Oant_3450 52 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 153010856 Common - multiple resistance and pH regulation protein F Oant_3535 42 COG2212 MnhF, Multisubunit Na+/H+ antiporter, MnhF subunit Inorganic ion transport and metabolism 153010590 Common - major facilitator superfamily MFS_1 Oant_3267 216 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010757 Common - type I secretion membrane fusion protein, HlyD family Oant_3436 125 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 153010725 Common - transcriptional regulator, LysR family Oant_3404 187 COG0583 LysR, Transcriptional regulator Transcription 153011161 Common - Myo-inositol catabolism IolB domain protein Oant_3840 53 COG3718 IolB, Uncharacterized enzyme involved in inositol metabolism Carbohydrate transport and metabolism 153010796 Common - helix-turn-helix- domain containing protein AraC type Oant_3475 136 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153011115 Common - regulatory protein LysR Oant_3794 135 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 153010753 Common - glycosyl transferase group 1 Oant_3432 181 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153011728 Common - protein of unknown function DUF995 Oant_4413 6 None None None 153011346 Common - transcriptional regulator, MarR family Oant_4026 110 COG1846 MarR, Transcriptional regulators Transcription 153010212 Common - putative transcriptional regulator, Crp/Fnr family Oant_2889 62 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153010624 Common - magnesium transporter Oant_3303 171 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 153011743 Common - 4-hydroxyphenylpyruvate dioxygenase Oant_4428 79 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 153010457 Common - methyltransferase FkbM family Oant_3134 8 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 153010359 Common - RNA-binding S4 domain protein Oant_3036 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 153010093 Common - extracellular solute-binding protein family 5 Oant_2769 203 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153011482 Common - transcriptional regulator, MarR family Oant_4167 79 COG1846 MarR, Transcriptional regulators Transcription 153010252 Common - aldo/keto reductase Oant_2929 145 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 153011543 Common - extracellular solute-binding protein family 1 Oant_4228 56 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 153010318 Common - transcriptional regulator, LysR family Oant_2995 189 COG0583 LysR, Transcriptional regulator Transcription 153011367 Common - putative transcriptional regulator, MerR family Oant_4049 138 COG0789 SoxR, Predicted transcriptional regulators Transcription 153010342 Common - ATP phosphoribosyltransferase Oant_3019 214 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 153010826 Common - binding-protein-dependent transport systems inner membrane component Oant_3505 184 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153010544 Common - conjugation TrbI family protein Oant_3221 59 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 153010376 Common - transcriptional regulator, LysR family Oant_3053 187 COG0583 LysR, Transcriptional regulator Transcription 153010993 Common - ribonuclease R Oant_3672 192 COG0557 VacB, Exoribonuclease R Transcription 153011637 Common - phage integrase family protein Oant_4322 77 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153011592 Common - Glutamate synthase (ferredoxin) Oant_4277 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 153011233 Common - Gluconolactonase Oant_3913 85 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 153011407 Common - transcriptional regulator, GntR family Oant_4090 134 COG1802 GntR, Transcriptional regulators Transcription 153011104 Common - ABC transporter related Oant_3783 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153010346 Common - hypothetical protein Oant_3023 3 None None None 153010976 Common - lipoate-protein ligase B Oant_3655 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 153011731 Common - UDP-glucose 4-epimerase Oant_4416 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 153010306 Common - protein of unknown function DUF6 transmembrane Oant_2983 68 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 153010166 Common - putative periplasmic binding protein with substrate ribose Oant_2843 83 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153011643 Common - transposase IS66 Oant_4328 61 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153010668 Common - ABC transporter related Oant_3347 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153010082 Common - hypothetical protein Oant_2757 9 COG4026 COG4026, Uncharacterized protein containing TOPRIM domain, potential nuclease General function prediction only 153010791 Common - putative transcriptional regulator, AsnC family Oant_3470 143 COG1522 Lrp, Transcriptional regulators Transcription 153011767 Common - protein of unknown function DUF105 Oant_4452 11 COG1865 COG1865, Uncharacterized conserved protein Function unknown 153010089 Common - Beta-glucosidase Oant_2765 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 153011063 Common - peptidase M19 renal dipeptidase Oant_3742 103 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 153010676 Common - hypothetical protein Oant_3355 14 None None None 153011605 Common - hypothetical protein Oant_4290 3 None None None 153011319 Common - inner-membrane translocator Oant_3999 148 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 153011611 Common - hypothetical protein Oant_4296 6 None None None 153011312 Common - YceI family protein Oant_3992 111 COG2353 COG2353, Uncharacterized conserved protein Function unknown 153010311 Common - Endoribonuclease L-PSP Oant_2988 91 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153010441 Common - UbiD family decarboxylase Oant_3118 154 COG0043 UbiD, 3-polyprenyl-4-hydroxybenzoate decarboxylase and related decarboxylases Coenzyme metabolism 153011308 Common - transcriptional regulator, LysR family Oant_3988 110 COG0583 LysR, Transcriptional regulator Transcription 153011059 Common - ABC transporter related Oant_3738 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153010652 Common - regulatory protein ArsR Oant_3331 163 COG0640 ArsR, Predicted transcriptional regulators Transcription 153011006 Pathogen - hypothetical protein Oant_3685 1 None None None 153010655 Common - ABC transporter related Oant_3334 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153011704 Common - von Willebrand factor type A Oant_4389 46 COG4548 NorD, Nitric oxide reductase activation protein Inorganic ion transport and metabolism 153010687 Common - major facilitator superfamily MFS_1 Oant_3366 91 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 153010632 Common - Amidohydrolase 3 Oant_3311 96 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 153010332 Common - transcriptional regulator, LysR family Oant_3009 122 COG0583 LysR, Transcriptional regulator Transcription 153011427 Common - Protein-N(pi)-phosphohistidine--sugar phosphotransferase Oant_4110 22 COG3732 SrlE, Phosphotransferase system sorbitol-specific component IIBC Carbohydrate transport and metabolism 153011325 Common - response regulator receiver protein Oant_4005 47 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 153010286 Common - Glutathione synthase Oant_2963 69 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 153010245 Common - protein of unknown function DUF849 Oant_2922 62 COG3246 COG3246, Uncharacterized conserved protein Function unknown 153010504 Common - hypothetical protein Oant_3181 6 None None None 153011180 Common - hypothetical protein Oant_3860 69 COG3000 ERG3, Sterol desaturase Lipid metabolism 153011374 Common - hypothetical protein Oant_4056 6 None None None 153010365 Common - peptidase U62 modulator of DNA gyrase Oant_3042 160 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 153011735 Common - ABC transporter related Oant_4420 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153010404 Pathogen - hypothetical protein Oant_3081 1 None None None 153010415 Common - ABC transporter related Oant_3092 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153011652 Pathogen - hypothetical protein Oant_4337 1 None None None 153010906 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Oant_3585 176 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones