Ochrobactrum anthropi ATCC 49188 chromosome 1, complete sequence NC_009667 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 153008948 Common - outer membrane serine protease Oant_1618 12 COG4571 OmpT, Outer membrane protease Cell envelope biogenesis, outer membrane 153009172 Common - RbsD or FucU transport Oant_1842 44 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 153007765 Common - transcriptional regulator, LysR family Oant_0420 187 COG0583 LysR, Transcriptional regulator Transcription 153008922 Common - transcriptional regulator, LysR family Oant_1592 175 COG0583 LysR, Transcriptional regulator Transcription 153009155 Common - ABC-2 type transporter Oant_1825 116 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 153009076 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Oant_1746 162 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 153009935 Common - RarD protein, DMT superfamily transporter Oant_2608 96 COG2962 RarD, Predicted permeases General function prediction only 153009314 Common - Lytic transglycosylase catalytic Oant_1984 38 COG4764 COG4764, Uncharacterized protein conserved in bacteria Function unknown 153007437 Common - protein of unknown function DUF1232 Oant_0092 36 COG3339 COG3339, Uncharacterized conserved protein Function unknown 153007942 Common - GCN5-related N-acetyltransferase Oant_0597 141 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153009148 Common - NUDIX hydrolase Oant_1818 11 None None None 153008524 Common - hypothetical protein Oant_1193 5 None None None 153010035 Common - choline dehydrogenase Oant_2709 93 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 153008129 Common - transcriptional regulator, LysR family Oant_0793 163 COG0583 LysR, Transcriptional regulator Transcription 153007949 Common - Chloride channel core Oant_0604 111 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 153008972 Common - export-related chaperone CsaA Oant_1642 119 COG0073 ARC1, EMAP domain General function prediction only 153008651 Common - aminoglycoside phosphotransferase Oant_1320 21 COG3231 Aph, Aminoglycoside phosphotransferase Translation, ribosomal structure and biogenesis 153009239 Common - DNA repair protein RadC Oant_1909 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 153009603 Common - acetyl-CoA carboxylase, biotin carboxyl carrier protein Oant_2273 183 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 153008346 Common - Electron transfer flavoprotein alpha/beta-subunit Oant_1011 153 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 153008909 Common - tRNA/rRNA methyltransferase (SpoU) Oant_1579 56 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 153007938 Common - hypothetical protein Oant_0593 45 COG4233 COG4233, Uncharacterized protein predicted to be involved in C-type cytochrome biogenesis Posttranslational modification, protein turnover, chaperones / Energy production and conversion 153008330 Common - hypoxanthine phosphoribosyltransferase Oant_0995 138 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 153008150 Common - FolC bifunctional protein Oant_0814 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 153007529 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Oant_0184 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 153009129 Common - GCN5-related N-acetyltransferase Oant_1799 115 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153007451 Common - heme exporter protein CcmA Oant_0106 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 153007727 Common - protein involved in cellulose biosynthesis (CelD)-like protein Oant_0382 12 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 153007496 Common - protein of unknown function DUF1052 Oant_0151 30 COG5321 COG5321, Uncharacterized protein conserved in bacteria Function unknown 153007568 Pathogen - hypothetical protein Oant_0223 1 None None None 153007891 Common - Pirin domain protein Oant_0546 142 COG1741 COG1741, Pirin-related protein General function prediction only 153009853 Common - 6,7-dimethyl-8-ribityllumazine synthase Oant_2526 207 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 153007845 Common - ATP synthase F0, A subunit Oant_0500 129 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 153010039 Common - HAD-superfamily hydrolase, subfamily IIB Oant_2714 79 COG1877 OtsB, Trehalose-6-phosphatase Carbohydrate transport and metabolism 153009078 Common - Polypeptide-transport-associated domain protein FtsQ-type Oant_1748 66 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 153009141 Common - K potassium transporter Oant_1811 88 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 153007532 Common - protein of unknown function UPF0102 Oant_0187 118 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 153009556 Common - short-chain dehydrogenase/reductase SDR Oant_2226 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153009942 Common - hypothetical protein Oant_2615 16 COG5451 COG5451, Predicted secreted protein Function unknown 153009042 Common - Rieske (2Fe-2S) domain protein Oant_1712 83 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 153007422 Common - Lytic transglycosylase catalytic Oant_0077 19 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 153008979 Common - hypothetical protein Oant_1649 8 None None None 153008569 Common - hypothetical protein Oant_1238 7 None None None 153009513 Common - multiple antibiotic resistance (MarC)-related protein Oant_2183 157 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 153008617 Common - aldehyde dehydrogenase Oant_1286 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153008250 Common - cobalt chelatase, pCobT subunit Oant_0915 41 COG4547 CobT, Cobalamin biosynthesis protein CobT (nicotinate-mononucleotide:5, 6-dimethylbenzimidazole phosphoribosyltransferase) Coenzyme metabolism 153009572 Common - hypothetical protein Oant_2242 14 COG3827 COG3827, Uncharacterized protein conserved in bacteria Function unknown 153008866 Pathogen - hypothetical protein Oant_1536 1 None None None 153009388 Common - Septum formation initiator Oant_2058 32 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 153007696 Common - ABC transporter related Oant_0351 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153007633 Common - Tagatose-6-phosphate kinase Oant_0288 33 COG4573 GatZ, Predicted tagatose 6-phosphate kinase Carbohydrate transport and metabolism 153008936 Common - hypothetical protein Oant_1606 35 COG5426 COG5426, Uncharacterized membrane protein Function unknown 153007556 Pathogen - hypothetical protein Oant_0211 1 None None None 153009338 Common - protein of unknown function DUF883 ElaB Oant_2008 5 COG4575 ElaB, Uncharacterized conserved protein Function unknown 153009299 Common - ribosomal protein S14 Oant_1969 204 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 153007414 Common - periplasmic binding protein/LacI transcriptional regulator Oant_0069 90 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153007355 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Oant_0010 222 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 153007710 Common - dihydroorotate dehydrogenase family protein Oant_0365 132 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 153008577 Common - response regulator receiver protein Oant_1246 135 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 153007512 Common - protein of unknown function DUF1239 Oant_0167 22 COG5375 COG5375, Uncharacterized protein conserved in bacteria Function unknown 153009392 Common - GCN5-related N-acetyltransferase Oant_2062 10 COG0456 RimI, Acetyltransferases General function prediction only 153009507 Common - Queuosine biosynthesis protein Oant_2177 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 153009399 Common - 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Oant_2069 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 153009908 Common - protein of unknown function DUF519 Oant_2581 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 153009117 Common - hypothetical protein Oant_1787 12 COG5471 COG5471, Uncharacterized conserved protein Function unknown 153009361 Common - uridylate kinase Oant_2031 227 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 153009120 Common - phage integrase family protein Oant_1790 26 None None None 153009734 Common - protein of unknown function DUF1467 Oant_2406 20 COG5454 COG5454, Predicted secreted protein Function unknown 153008088 Common - Methionine adenosyltransferase Oant_0752 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 153007739 Common - acetylornithine and succinylornithine aminotransferase Oant_0394 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 153010048 Common - Transposase and inactivated derivatives-like protein Oant_2723 54 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 153008206 Common - Alanine racemase Oant_0870 128 COG1609 PurR, Transcriptional regulators Transcription 153008361 Common - hypothetical protein Oant_1026 5 None None None 153007825 Common - Endopeptidase Clp Oant_0480 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153008563 Common - hypothetical protein Oant_1232 13 None None None 153008075 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabA Oant_0739 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 153009636 Common - phage portal protein, lambda family Oant_2308 35 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 153009604 Common - acetyl-CoA carboxylase, biotin carboxylase Oant_2274 237 COG0439 AccC, Biotin carboxylase Lipid metabolism 153007412 Common - hypothetical protein Oant_0067 15 COG4954 COG4954, Uncharacterized protein conserved in bacteria Function unknown 153008960 Common - Aminoacyl-tRNA hydrolase Oant_1630 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 153007443 Common - ABC transporter related Oant_0098 249 COG4181 COG4181, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 153009615 Common - hypothetical protein Oant_2285 2 None None None 153009660 Common - protein of unknown function DUF1127 Oant_2332 7 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 153009346 Common - L-serine dehydratase 1 Oant_2016 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 153009053 Common - 5,10-methylenetetrahydrofolate reductase Oant_1723 145 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 153009373 Common - glutamyl-tRNA synthetase Oant_2043 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 153007843 Common - cell wall hydrolase SleB Oant_0498 48 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 153007740 Common - ornithine carbamoyltransferase Oant_0395 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 153009588 Common - hypothetical protein Oant_2258 84 COG2945 COG2945, Predicted hydrolase of the alpha/beta superfamily General function prediction only 153009746 Common - NADH-quinone oxidoreductase, F subunit Oant_2418 167 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 153008411 Common - signal recognition particle protein Oant_1077 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 153008122 Common - orotidine 5'-phosphate decarboxylase Oant_0786 171 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 153008159 Common - Asp/Glu racemase Oant_0823 187 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 153009812 Common - extracellular solute-binding protein family 1 Oant_2485 126 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153007464 Common - protein of unknown function DUF218 Oant_0119 9 COG1434 COG1434, Uncharacterized conserved protein Function unknown 153009137 Common - Pyridoxal-5'-phosphate-dependent protein beta subunit Oant_1807 194 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 153008845 Common - hypothetical protein Oant_1515 5 None None None 153009381 Common - Triose-phosphate isomerase Oant_2051 219 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 153008730 Common - inner-membrane translocator Oant_1399 152 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 153008763 Common - nucleoside recognition domain protein Oant_1432 22 COG3314 COG3314, Uncharacterized protein conserved in bacteria Function unknown 153007903 Common - hypothetical protein Oant_0558 32 COG3911 COG3911, Predicted ATPase General function prediction only 153007456 Pathogen - hypothetical protein Oant_0111 1 None None None 153007581 Pathogen - hypothetical protein Oant_0236 1 None None None 153009901 Common - hypothetical protein Oant_2574 73 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 153008910 Common - regulatory protein ArsR Oant_1580 139 COG0640 ArsR, Predicted transcriptional regulators Transcription 153008055 Common - hypothetical protein Oant_0719 21 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 153009979 Common - hypothetical protein Oant_2653 18 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 153009447 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Oant_2117 201 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 153009846 Common - 3-oxoacyl-(acyl-carrier-protein) synthase III Oant_2519 225 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 153007975 Common - Rv0623 family protein transcription factor Oant_0632 2 COG4423 COG4423, Uncharacterized protein conserved in bacteria Function unknown 153009039 Common - Nicotinamidase Oant_1709 119 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 153007652 Common - amidohydrolase 2 Oant_0307 50 COG3618 COG3618, Predicted metal-dependent hydrolase of the TIM-barrel fold General function prediction only 153009025 Common - hypothetical protein Oant_1695 31 COG5343 COG5343, Uncharacterized protein conserved in bacteria Function unknown 153009232 Common - ABC transporter related Oant_1902 249 COG1124 DppF, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153008455 Common - major facilitator superfamily MFS_1 Oant_1121 62 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 153007836 Pathogen - hypothetical protein Oant_0491 2 None None None 153010034 Common - transcriptional regulator, TetR family Oant_2708 64 COG3226 COG3226, Uncharacterized protein conserved in bacteria Function unknown 153009080 Common - cell division protein FtsZ Oant_1750 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 153009175 Pathogen - hypothetical protein Oant_1845 1 None None None 153009807 Common - hypothetical protein Oant_2480 9 COG4026 COG4026, Uncharacterized protein containing TOPRIM domain, potential nuclease General function prediction only 153009875 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_2548 45 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 153009419 Common - carbohydrate kinase, YjeF related protein Oant_2089 219 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 153007874 Common - phosphoribosylamine--glycine ligase Oant_0529 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 153008476 Common - thiamine ABC transporter, periplasmic binding protein Oant_1142 65 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 153009777 Common - protein of unknown function UPF0118 Oant_2449 180 COG0628 PerM, Predicted permease General function prediction only 153009275 Common - ribosomal protein L10 Oant_1945 211 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 153008814 Common - hypothetical protein Oant_1483 2 None None None 153008181 Common - MltA domain protein Oant_0845 93 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 153009530 Common - excinuclease ABC, A subunit Oant_2200 237 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 153009015 Common - Na+ cotransporter Oant_1685 71 COG1283 NptA, Na+/phosphate symporter Inorganic ion transport and metabolism 153008665 Common - peptidase U6 penicillin-insensitive murein endopeptidase Oant_1334 40 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 153008570 Pathogen - hypothetical protein Oant_1239 1 None None None 153008853 Pathogen - hypothetical protein Oant_1523 1 COG2378 COG2378, Predicted transcriptional regulator Transcription 153009311 Common - ribosomal protein L17 Oant_1981 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 153007965 Common - hypothetical protein Oant_0622 21 None None None 153007831 Common - polysaccharide deacetylase Oant_0486 11 None None None 153009972 Common - porin Oant_2645 13 None None None 153009427 Common - NAD+ synthetase Oant_2097 236 COG0171 NadE, NAD synthase Coenzyme metabolism 153008855 Pathogen - hypothetical protein Oant_1525 1 None None None 153007662 Common - short-chain dehydrogenase/reductase SDR Oant_0317 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153008022 Common - P-type conjugative transfer protein VirB9 Oant_0683 43 COG3504 VirB9, Type IV secretory pathway, VirB9 components Intracellular trafficking and secretion 153009622 Common - phage tail tape measure protein, TP901 family Oant_2292 27 COG5283 COG5283, Phage-related tail protein Function unknown 153009566 Common - polar amino acid ABC transporter, inner membrane subunit Oant_2236 174 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 153008833 Pathogen - hypothetical protein Oant_1502 1 None None None 153009192 Common - MscS Mechanosensitive ion channel Oant_1862 202 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 153007902 Common - CDP-diacylglycerol--serine O-phosphatidyltransferase Oant_0557 143 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 153007571 Common - transcriptional repressor, LexA family Oant_0226 64 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 153007578 Pathogen - hypothetical protein Oant_0233 1 None None None 153007588 Common - phage portal protein, HK97 family Oant_0243 68 COG4695 COG4695, Phage-related protein Function unknown 153008086 Common - protein of unknown function DUF150 Oant_0750 166 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 153008230 Common - putative transcriptional regulator, XRE family Oant_0894 16 COG1396 HipB, Predicted transcriptional regulators Transcription 153007646 Common - sarcosine oxidase, beta subunit family Oant_0301 96 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153008499 Common - ribosomal protein L36 Oant_1167 70 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 153009721 Common - inositol monophosphatase Oant_2393 187 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 153008679 Common - transcriptional regulator, LysR family Oant_1348 156 COG0583 LysR, Transcriptional regulator Transcription 153008010 Pathogen - hypothetical protein Oant_0671 1 None None None 153009209 Common - protein of unknown function DUF6 transmembrane Oant_1879 55 COG2510 COG2510, Predicted membrane protein Function unknown 153009489 Common - Phosphoribosyl-AMP cyclohydrolase Oant_2159 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 153008941 Common - NUDIX hydrolase Oant_1611 117 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 153009687 Common - putative transcriptional regulator, AsnC family Oant_2359 138 COG1522 Lrp, Transcriptional regulators Transcription 153008497 Common - pyruvate kinase Oant_1165 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 153008099 Common - peptidase M29 aminopeptidase II Oant_0763 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 153008339 Common - putative ribonuclease BN Oant_1004 69 COG1295 Rbn, Predicted membrane protein Function unknown 153009300 Common - ribosomal protein S8 Oant_1970 246 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 153007366 Common - DNA polymerase III, subunits gamma and tau Oant_0021 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 153008706 Common - transcriptional regulator, MarR family Oant_1375 97 COG1846 MarR, Transcriptional regulators Transcription 153007706 Common - extracellular solute-binding protein family 1 Oant_0361 88 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153009797 Common - regulatory protein IclR Oant_2470 38 COG1414 IclR, Transcriptional regulator Transcription 153008004 Common - Threonine synthase Oant_0665 109 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 153009484 Common - threonyl-tRNA synthetase Oant_2154 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153008951 Common - ABC transporter related Oant_1621 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153009983 Common - Endonuclease/exonuclease/phosphatase Oant_2657 23 COG3021 COG3021, Uncharacterized protein conserved in bacteria Function unknown 153007591 Common - phage head-tail adaptor, putative Oant_0246 6 COG5614 COG5614, Bacteriophage head-tail adaptor General function prediction only 153009247 Common - Homoserine dehydrogenase Oant_1917 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 153008008 Common - putative transcriptional regulator, XRE family Oant_0669 29 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 153007598 Common - hypothetical protein Oant_0253 3 None None None 153008152 Common - thioredoxin Oant_0816 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 153009199 Common - glycosyl transferase family 39 Oant_1869 9 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 153008512 Pathogen - hypothetical protein Oant_1181 2 None None None 153008705 Common - Creatininase Oant_1374 82 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 153007522 Common - protein of unknown function DUF540 Oant_0177 28 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 153009758 Common - Na+/H+ antiporter NhaA Oant_2430 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 153007779 Common - Superoxide dismutase Oant_0434 206 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 153009561 Common - molybdenum cofactor biosynthesis protein A Oant_2231 200 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 153008427 Common - Usg family protein Oant_1093 24 COG5425 COG5425, Usg protein, probable subunit of phosphoribosylanthranilate isomerase Amino acid transport and metabolism 153008561 Common - GCN5-related N-acetyltransferase Oant_1230 22 COG0456 RimI, Acetyltransferases General function prediction only 153009554 Common - Peptidoglycan-binding domain 1 protein Oant_2224 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 153009167 Common - extracellular solute-binding protein family 5 Oant_1837 192 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153007505 Common - hypothetical protein Oant_0160 70 COG3176 COG3176, Putative hemolysin General function prediction only 153009294 Common - ribosomal protein L29 Oant_1964 174 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 153009425 Common - phospho-2-dehydro-3-deoxyheptonate aldolase Oant_2095 73 COG3200 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 153008982 Common - protease inhibitor Kazal-type Oant_1652 4 None None None 153008474 Common - ABC transporter, ATPase subunit, ThiQ subfamily Oant_1140 249 COG3840 ThiQ, ABC-type thiamine transport system, ATPase component Coenzyme metabolism 153007900 Common - ABC transporter related Oant_0555 249 COG5265 ATM1, ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components Posttranslational modification, protein turnover, chaperones 153009404 Common - diacylglycerol kinase catalytic region Oant_2074 119 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 153010022 Common - Gluconate 2-dehydrogenase (acceptor) Oant_2696 53 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 153009207 Common - cobaltochelatase, CobN subunit Oant_1877 89 COG1429 CobN, Cobalamin biosynthesis protein CobN and related Mg-chelatases Coenzyme metabolism 153008484 Pathogen - hypothetical protein Oant_1151 1 None None None 153008225 Pathogen - hypothetical protein Oant_0889 1 None None None 153007789 Common - Tripartite ATP-independent periplasmic transporter DctQ component Oant_0444 73 COG4665 FcbT2, TRAP-type mannitol/chloroaromatic compound transport system, small permease component Secondary metabolites biosynthesis, transport, and catabolism 153008420 Common - glycerol kinase Oant_1086 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 153009431 Common - short-chain dehydrogenase/reductase SDR Oant_2101 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153008084 Common - protein of unknown function DUF448 Oant_0748 44 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 153008548 Common - TolA protein Oant_1217 18 COG5373 COG5373, Predicted membrane protein Function unknown 153007880 Common - short-chain dehydrogenase/reductase SDR Oant_0535 227 COG0623 FabI, Enoyl- acyl-carrier-protein 153007620 Common - sulfatase Oant_0275 44 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 153008265 Common - malate dehydrogenase, NAD-dependent Oant_0930 199 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 153008649 Common - 2-polyprenylphenol 6-hydroxylase Oant_1318 185 COG0661 AarF, Predicted unusual protein kinase General function prediction only 153009406 Common - Serine-type D-Ala-D-Ala carboxypeptidase Oant_2076 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 153007889 Common - Transglycosylase-associated protein Oant_0544 6 COG2261 COG2261, Predicted membrane protein Function unknown 153008766 Common - histidine ammonia-lyase Oant_1435 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 153009288 Common - Ribosomal protein L25/L23 Oant_1958 230 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 153007833 Common - small GTP-binding protein Oant_0488 237 COG1160 COG1160, Predicted GTPases General function prediction only 153008167 Common - alpha/beta hydrolase fold Oant_0831 134 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153010062 Common - methyltransferase type 11 Oant_2738 7 None None None 153007676 Common - Urease accessory protein UreD Oant_0331 77 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 153008683 Pathogen - hypothetical protein Oant_1352 2 None None None 153009444 Common - protein of unknown function DUF922 Oant_2114 7 COG5661 COG5661, Predicted secreted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 153008514 Common - AMP-dependent synthetase and ligase Oant_1183 217 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 153008138 Common - Isoprenylcysteine carboxyl methyltransferase Oant_0802 38 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 153008353 Common - sulfatase Oant_1018 66 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 153009335 Common - protein of unknown function DUF924 Oant_2005 63 COG3803 COG3803, Uncharacterized protein conserved in bacteria Function unknown 153008187 Common - shikimate 5-dehydrogenase Oant_0851 226 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 153008210 Common - aldehyde dehydrogenase Oant_0874 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153007808 Common - copper-translocating P-type ATPase Oant_0463 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 153009364 Common - Phosphatidate cytidylyltransferase Oant_2034 211 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 153008892 Pathogen - hypothetical protein Oant_1562 2 None None None 153009229 Common - precorrin-3B synthase Oant_1899 92 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 153007566 Pathogen - hypothetical protein Oant_0221 1 None None None 153007664 Common - Mandelate racemase/muconate lactonizing protein Oant_0319 109 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 153007471 Common - phenazine biosynthesis protein PhzF family Oant_0126 111 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 153009520 Common - putative acetyltransferase protein Oant_2190 66 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 153008116 Common - Phosphoglycerate mutase Oant_0780 12 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 153008332 Common - diaminopimelate decarboxylase Oant_0997 218 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 153007634 Common - PfkB domain protein Oant_0289 163 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153007838 Common - signal peptidase I Oant_0493 113 COG4959 TraF, Type IV secretory pathway, protease TraF Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153008064 Common - type II secretion system protein Oant_0728 75 COG2064 TadC, Flp pilus assembly protein TadC Cell motility and secretion / Intracellular trafficking and secretion 153008821 Common - Phage tail tube protein FII-like protein Oant_1490 6 COG3498 COG3498, Phage tail tube protein FII General function prediction only 153008393 Common - protein of unknown function DUF163 Oant_1059 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 153008536 Common - Inositol-phosphate phosphatase Oant_1205 214 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 153008829 Common - Baseplate J family protein Oant_1498 35 COG3948 COG3948, Phage-related baseplate assembly protein General function prediction only 153007755 Common - large conductance mechanosensitive channel protein Oant_0410 119 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 153007872 Common - Enoyl-CoA hydratase/isomerase Oant_0527 176 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 153007605 Pathogen - Methyltransferase type 11 Oant_0260 1 COG4627 COG4627, Uncharacterized protein conserved in bacteria Function unknown 153009031 Common - hypothetical protein Oant_1701 8 None None None 153009548 Common - biotin/lipoate A/B protein ligase Oant_2218 58 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 153007784 Common - proline racemase Oant_0439 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 153009494 Pathogen - hypothetical protein Oant_2164 1 None None None 153009268 Common - CBS domain containing protein Oant_1938 174 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 153009393 Common - dihydrolipoamide dehydrogenase Oant_2063 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 153007358 Common - binding-protein-dependent transport systems inner membrane component Oant_0013 219 COG4174 COG4174, ABC-type uncharacterized transport system, permease component General function prediction only 153009306 Common - preprotein translocase, SecY subunit Oant_1976 236 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 153008883 Pathogen - hypothetical protein Oant_1553 1 None None None 153009693 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Oant_2365 108 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 153008888 Pathogen - hypothetical protein Oant_1558 2 None None None 153009023 Common - protein of unknown function DUF541 Oant_1693 91 COG2968 COG2968, Uncharacterized conserved protein Function unknown 153009541 Common - multi-sensor signal transduction histidine kinase Oant_2211 218 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 153008642 Common - hypothetical protein Oant_1311 4 None None None 153009437 Common - protein of unknown function DUF140 Oant_2107 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 153010067 Common - IS66 Orf2 family protein Oant_2743 52 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153007932 Common - protein of unknown function DUF983 Oant_0587 24 COG5349 COG5349, Uncharacterized protein conserved in bacteria Function unknown 153008302 Common - uracil-xanthine permease Oant_0967 124 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 153008160 Common - Phosphotransferase system, phosphocarrier protein HPr Oant_0824 139 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 153007490 Common - protein of unknown function DUF156 Oant_0145 70 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 153007886 Common - histone deacetylase superfamily Oant_0541 162 COG0123 AcuC, Deacetylases, including yeast histone deacetylase and acetoin utilization protein Chromatin structure and dynamics / Secondary metabolites biosynthesis, transport, and catabolism 153007993 Common - hypothetical protein Oant_0651 9 None None None 153007924 Common - peptidase U62 modulator of DNA gyrase Oant_0579 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 153008831 Common - Phage P2 baseplate assembly protein gpV-like protein Oant_1500 24 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 153010043 Common - dTDP-4-dehydrorhamnose reductase Oant_2718 171 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 153008838 Common - Methyltransferase type 12 Oant_1508 49 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153007627 Common - thiazole biosynthesis family protein Oant_0282 166 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 153009963 Common - (p)ppGpp synthetase I, SpoT/RelA Oant_2636 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 153007951 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Oant_0606 40 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 153009460 Common - PRC-barrel domain protein Oant_2130 26 None None None 153008304 Common - protein of unknown function DUF6 transmembrane Oant_0969 69 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 153008598 Common - major facilitator superfamily MFS_1 Oant_1267 140 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153009835 Common - hypothetical protein Oant_2508 34 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 153008594 Common - putative transcriptional regulator, AsnC family Oant_1263 148 COG1522 Lrp, Transcriptional regulators Transcription 153009654 Pathogen - hypothetical protein Oant_2326 1 None None None 153007913 Common - ribosomal protein S18 Oant_0568 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 153008217 Common - ABC transporter related Oant_0881 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153008788 Common - hypothetical protein Oant_1457 18 COG4821 COG4821, Uncharacterized protein containing SIS (Sugar ISomerase) phosphosugar binding domain General function prediction only 153009094 Common - UvrD/REP helicase Oant_1764 230 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 153008505 Pathogen - protein of unknown function DUF1192 Oant_1173 2 COG5509 COG5509, Uncharacterized small protein containing a coiled-coil domain Function unknown 153007801 Common - Guanine deaminase Oant_0456 167 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 153009649 Common - putative phage repressor Oant_2321 13 COG2932 COG2932, Predicted transcriptional regulator Transcription 153007968 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Oant_0625 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153008895 Common - DegT/DnrJ/EryC1/StrS aminotransferase Oant_1565 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 153008555 Common - phosphoglucosamine mutase Oant_1224 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 153008663 Common - glucokinase Oant_1332 91 COG0837 Glk, Glucokinase Carbohydrate transport and metabolism 153009001 Common - RNA-directed DNA polymerase (Reverse transcriptase) Oant_1671 94 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 153007392 Pathogen - hypothetical protein Oant_0047 1 None None None 153009002 Common - aminotransferase class I and II Oant_1672 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153008751 Common - Galactose 1-dehydrogenase Oant_1420 93 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153009102 Pathogen - hypothetical protein Oant_1772 2 None None None 153008634 Pathogen - hypothetical protein Oant_1303 2 None None None 153007530 Common - putative oxygen-independent coproporphyrinogen III oxidase Oant_0185 216 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 153008546 Common - Tol-Pal system TolQ Oant_1215 131 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 153009897 Pathogen - hypothetical protein Oant_2570 1 None None None 153009878 Common - regulatory protein ArsR Oant_2551 66 COG0640 ArsR, Predicted transcriptional regulators Transcription 153007655 Common - binding-protein-dependent transport systems inner membrane component Oant_0310 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153007377 Common - hypothetical protein Oant_0032 16 COG4530 COG4530, Uncharacterized protein conserved in bacteria Function unknown 153007615 Common - transcriptional regulator, Fis family Oant_0270 77 COG3284 AcoR, Transcriptional activator of acetoin/glycerol metabolism Secondary metabolites biosynthesis, transport, and catabolism / Transcription 153009829 Common - cytochrome oxidase assembly Oant_2502 48 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 153007683 Common - urease accessory protein UreG Oant_0338 148 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 153008248 Common - heat shock protein DnaJ domain protein Oant_0913 98 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 153007947 Pathogen - hypothetical protein Oant_0602 2 None None None 153009937 Common - glutathione-dependent formaldehyde-activating GFA Oant_2610 65 COG3791 COG3791, Uncharacterized conserved protein Function unknown 153008400 Common - protein of unknown function DUF1275 Oant_1066 21 COG3619 COG3619, Predicted membrane protein Function unknown 153008760 Common - binding-protein-dependent transport systems inner membrane component Oant_1429 197 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153008124 Common - phosphatidylethanolamine N-methyltransferase / phosphatidyl-N-methylethanolamine N-methyltransferase Oant_0788 43 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 153009845 Common - integration host factor, alpha subunit Oant_2518 196 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 153008919 Common - Substrate-binding region of ABC-type glycine betaine transport system Oant_1589 63 COG2113 ProX, ABC-type proline/glycine betaine transport systems, periplasmic components Amino acid transport and metabolism 153008770 Common - hypothetical protein Oant_1439 13 COG3794 PetE, Plastocyanin Energy production and conversion 153009882 Common - polar amino acid ABC transporter, inner membrane subunit Oant_2555 183 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153009926 Common - DNA polymerase III chi subunit HolC Oant_2599 37 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 153008526 Common - metallophosphoesterase Oant_1195 81 COG1692 COG1692, Uncharacterized protein conserved in bacteria Function unknown 153008374 Common - ATPase AAA-2 domain protein Oant_1039 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 153007898 Common - Peptidoglycan-binding LysM Oant_0553 42 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 153009082 Common - ComL, hypothetical competence protein Oant_1752 130 COG4105 ComL, DNA uptake lipoprotein General function prediction only 153008447 Common - inner-membrane translocator Oant_1113 140 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 153008107 Common - phosphate ABC transporter, phosphate-binding protein Oant_0771 125 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 153009890 Pathogen - hypothetical protein Oant_2563 1 None None None 153009202 Common - cobyric acid synthase CobQ Oant_1872 153 COG1492 CobQ, Cobyric acid synthase Coenzyme metabolism 153008322 Common - phospholipid/glycerol acyltransferase Oant_0987 153 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 153009568 Common - Glutathione S-transferase domain protein Oant_2238 93 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153008758 Common - aminotransferase class IV Oant_1427 195 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 153008200 Pathogen - hypothetical protein Oant_0864 2 None None None 153009058 Common - hypothetical protein Oant_1728 11 COG5379 BtaA, S-adenosylmethionine:diacylglycerol 3-amino-3-carboxypropyl transferase Lipid metabolism 153009800 Common - ABC transporter related Oant_2473 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153007484 Common - DNA gyrase, B subunit Oant_0139 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 153008619 Common - extracellular solute-binding protein family 5 Oant_1288 206 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153008792 Common - transcriptional regulator, LysR family Oant_1461 179 COG0583 LysR, Transcriptional regulator Transcription 153009785 Common - transcriptional regulator, XRE family Oant_2458 27 COG1476 COG1476, Predicted transcriptional regulators Transcription 153008385 Common - ribosomal protein L27 Oant_1051 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 153009164 Common - short-chain dehydrogenase/reductase SDR Oant_1834 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153010027 Common - Superoxide dismutase Oant_2701 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 153009774 Common - membrane protein of uknown function UCP014873 Oant_2446 25 COG4803 COG4803, Predicted membrane protein Function unknown 153010023 Common - protein of unknown function DUF853 NPT hydrolase putative Oant_2697 78 COG0433 COG0433, Predicted ATPase General function prediction only 153009999 Common - histidine kinase Oant_2673 202 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153009674 Common - putative transcriptional regulator Oant_2346 144 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 153008245 Common - 3-dehydroquinate synthase Oant_0910 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 153009737 Common - biotin--acetyl-CoA-carboxylase ligase Oant_2409 223 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 153008714 Common - aa3 type cytochrome c oxidase subunit IV Oant_1383 6 None None None 153008031 Common - beta-lactamase domain protein Oant_0692 137 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 153009259 Pathogen - hypothetical protein Oant_1929 1 None None None 153008713 Common - hypothetical protein Oant_1382 7 None None None 153008390 Common - gamma-glutamyl phosphate reductase Oant_1056 189 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 153007466 Common - sulfate ABC transporter, inner membrane subunit CysT Oant_0121 219 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 153008409 Common - lytic murein transglycosylase Oant_1075 102 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 153009458 Common - beta-lactamase Oant_2128 68 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 153008096 Common - ribosomal-protein-alanine acetyltransferase Oant_0760 188 COG0456 RimI, Acetyltransferases General function prediction only 153008324 Common - protein of unknown function YGGT Oant_0989 103 COG0762 COG0762, Predicted integral membrane protein Function unknown 153008231 Common - SMF family protein Oant_0895 209 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 153010001 Common - hypothetical protein Oant_2675 3 None None None 153009390 Common - Transketolase central region Oant_2060 208 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 153009480 Common - MazG family protein Oant_2150 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 153008659 Common - cob(II)yrinic acid a,c-diamide reductase Oant_1328 69 COG0778 NfnB, Nitroreductase Energy production and conversion 153009152 Common - protein of unknown function DUF187 Oant_1822 42 COG1649 COG1649, Uncharacterized protein conserved in bacteria Function unknown 153008999 Common - ABC transporter related Oant_1669 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153009634 Common - hypothetical protein Oant_2304 2 None None None 153007416 Common - ABC transporter related Oant_0071 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153008141 Common - benzoate transporter Oant_0805 60 COG3135 BenE, Uncharacterized protein involved in benzoate metabolism Secondary metabolites biosynthesis, transport, and catabolism 153009928 Common - permease YjgP/YjgQ family protein Oant_2601 87 COG0795 COG0795, Predicted permeases General function prediction only 153008298 Common - ABC transporter related Oant_0963 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153009508 Common - peptidyl-prolyl cis-trans isomerase cyclophilin type Oant_2178 200 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 153007811 Common - cytochrome c oxidase, cbb3-type, subunit III Oant_0466 80 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 153007445 Common - protein of unknown function UPF0005 Oant_0100 141 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 153008376 Common - peptidase M23B Oant_1041 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 153008690 Common - hypothetical protein Oant_1359 9 None None None 153008803 Common - hypothetical protein Oant_1472 18 COG2267 PldB, Lysophospholipase Lipid metabolism 153007737 Common - glycosyl transferase group 1 Oant_0392 143 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153009515 Common - phosphonate ABC transporter, inner membrane subunit Oant_2185 103 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 153008155 Common - Nucleotidyl transferase Oant_0819 198 COG1208 GCD1, Nucleoside-diphosphate-sugar pyrophosphorylase involved in lipopolysaccharide biosynthesis/translation initiation factor 2B, gamma/epsilon subunits (eIF-2Bgamma/eIF-2Bepsilon) Cell envelope biogenesis, outer membrane / Translation, ribosomal structure and biogenesis 153008980 Common - putative cold-shock DNA-binding domain protein Oant_1650 174 COG1278 CspC, Cold shock proteins Transcription 153009486 Common - protein of unknown function DUF37 Oant_2156 179 COG0759 COG0759, Uncharacterized conserved protein Function unknown 153008482 Pathogen - hypothetical protein Oant_1149 1 None None None 153009068 Common - Peptidoglycan glycosyltransferase Oant_1738 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 153007435 Common - radical SAM enzyme, Cfr family Oant_0090 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 153007563 Pathogen - hypothetical protein Oant_0218 1 None None None 153009799 Common - binding-protein-dependent transport systems inner membrane component Oant_2472 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153009681 Common - iron-sulfur cluster assembly accessory protein Oant_2353 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 153007798 Common - Xanthine dehydrogenase accessory protein XdhC Oant_0453 65 COG1975 XdhC, Xanthine and CO dehydrogenases maturation factor, XdhC/CoxF family Posttranslational modification, protein turnover, chaperones 153008363 Common - competence protein F, putative Oant_1028 169 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 153009146 Common - BA14K family protein Oant_1816 6 None None None 153008020 Common - hypothetical protein Oant_0681 8 None None None 153008120 Common - SMP-30/Gluconolaconase/LRE domain protein Oant_0784 75 COG3386 COG3386, Gluconolactonase Carbohydrate transport and metabolism 153009744 Common - NADH dehydrogenase (quinone) Oant_2416 190 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 153009985 Common - phage SPO1 DNA polymerase-related protein Oant_2659 153 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 153009096 Common - protein of unknown function DUF336 Oant_1766 20 COG4702 COG4702, Uncharacterized conserved protein Function unknown 153008507 Common - protein of unknown function DUF1013 Oant_1175 41 COG3820 COG3820, Uncharacterized protein conserved in bacteria Function unknown 153009051 Common - hypothetical protein Oant_1721 4 COG5586 COG5586, Uncharacterized conserved protein Function unknown 153010012 Common - Amidase Oant_2686 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 153009157 Common - periplasmic binding protein Oant_1827 35 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 153007716 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Oant_0371 158 COG0546 Gph, Predicted phosphatases General function prediction only 153009230 Common - precorrin-6y C5,15-methyltransferase (decarboxylating), CbiE subunit Oant_1900 102 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 153008219 Common - hypothetical protein Oant_0883 2 None None None 153009678 Common - Sporulation domain protein Oant_2350 15 COG3266 DamX, Uncharacterized protein conserved in bacteria Function unknown 153007940 Common - protein of unknown function DUF179 Oant_0595 126 COG1678 COG1678, Putative transcriptional regulator Transcription 153007489 Common - Alcohol dehydrogenase class III/S-(hydroxymethyl)glutathione dehydrogenase Oant_0144 209 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 153009375 Common - SOS-response transcriptional repressor, LexA Oant_2045 168 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 153009344 Common - protein of unknown function DUF218 Oant_2014 93 COG1434 COG1434, Uncharacterized conserved protein Function unknown 153008688 Common - pyrimidine 5'-nucleotidase Oant_1357 45 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 153009594 Common - peptidase M23B Oant_2264 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 153008912 Common - extracellular solute-binding protein family 5 Oant_1582 210 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153007725 Common - protein of unknown function DUF344 Oant_0380 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 153007453 Common - heme exporter protein CcmC Oant_0108 125 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 153008273 Common - dihydrolipoamide dehydrogenase Oant_0938 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 153008564 Common - Inorganic diphosphatase Oant_1233 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 153008134 Common - phenylalanyl-tRNA synthetase, alpha subunit Oant_0798 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 153008697 Common - hypothetical protein Oant_1366 16 None None None 153008006 Common - regulatory protein IclR Oant_0667 109 COG1414 IclR, Transcriptional regulator Transcription 153008204 Common - luciferase family protein Oant_0868 64 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 153010025 Common - ErfK/YbiS/YcfS/YnhG family protein Oant_2699 66 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153008472 Common - MOSC domain containing protein Oant_1138 79 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 153009694 Common - phosphonate metabolism protein PhnM Oant_2366 55 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 153007426 Common - hypothetical protein Oant_0081 25 COG4544 COG4544, Uncharacterized conserved protein Function unknown 153009790 Common - glycerol-3-phosphate responsive antiterminator Oant_2463 26 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 153007648 Common - sarcosine oxidase, alpha subunit family Oant_0303 183 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 153009944 Common - hypothetical protein Oant_2617 6 None None None 153008543 Common - Holliday junction DNA helicase RuvA Oant_1212 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 153008943 Common - Aspartyl/Asparaginyl beta-hydroxylase Oant_1613 38 COG3555 COG3555, Aspartyl/asparaginyl beta-hydroxylase and related dioxygenases Posttranslational modification, protein turnover, chaperones 153008173 Common - hypothetical protein Oant_0837 6 None None None 153007618 Common - protein of unknown function DUF779 Oant_0273 42 COG3564 COG3564, Uncharacterized protein conserved in bacteria Function unknown 153008418 Common - NAD-glutamate dehydrogenase Oant_1084 77 COG2902 COG2902, NAD-specific glutamate dehydrogenase Amino acid transport and metabolism 153008732 Common - ABC transporter related Oant_1401 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153008001 Common - protein of unknown function DUF112 transmembrane Oant_0662 75 COG3333 COG3333, Uncharacterized protein conserved in bacteria Function unknown 153008746 Common - Monosaccharide-transporting ATPase Oant_1415 133 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153009811 Common - binding-protein-dependent transport systems inner membrane component Oant_2484 156 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153008989 Common - protein of unknown function DUF1176 Oant_1659 11 None None None 153007424 Common - DNA polymerase III, alpha subunit Oant_0079 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 153007787 Common - integral membrane sensor signal transduction histidine kinase Oant_0442 165 COG4564 COG4564, Signal transduction histidine kinase Signal transduction mechanisms 153009700 Common - Beta-ketoacyl synthase Oant_2372 166 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153008535 Common - hypothetical protein Oant_1204 28 None None None 153009501 Common - transcriptional regulator, LysR family Oant_2171 180 COG0583 LysR, Transcriptional regulator Transcription 153008934 Common - putative glutathione S-transferase Oant_1604 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153007905 Common - amidophosphoribosyltransferase Oant_0560 239 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 153009685 Common - nuclease (SNase domain protein) Oant_2357 42 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 153009545 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Oant_2215 23 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 153008579 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Oant_1248 167 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153009906 Common - Nitrate reductase Oant_2579 180 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 153009732 Common - lipoprotein releasing system, transmembrane protein, LolC/E family Oant_2404 192 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 153008432 Common - hypothetical protein Oant_1098 56 COG4637 COG4637, Predicted ATPase General function prediction only 153010056 Common - transposase IS4 family protein Oant_2732 68 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009211 Common - protein of unknown function DUF1332 Oant_1881 4 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 153007818 Common - ErfK/YbiS/YcfS/YnhG family protein Oant_0473 83 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153009727 Common - hypothetical protein Oant_2399 16 None None None 153008495 Common - N-formylglutamate amidohydrolase Oant_1163 41 COG3931 COG3931, Predicted N-formylglutamate amidohydrolase Amino acid transport and metabolism 153008077 Common - short-chain dehydrogenase/reductase SDR Oant_0741 231 COG0623 FabI, Enoyl- acyl-carrier-protein 153009474 Common - diguanylate cyclase Oant_2144 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153009249 Common - fructose-1,6-bisphosphatase, class II Oant_1919 112 COG1494 GlpX, Fructose-1,6-bisphosphatase/sedoheptulose 1,7-bisphosphatase and related proteins Carbohydrate transport and metabolism 153007576 Pathogen - hypothetical protein Oant_0231 1 None None None 153009755 Common - Activator of Hsp90 ATPase 1 family protein Oant_2427 56 COG3832 COG3832, Uncharacterized conserved protein Function unknown 153007641 Common - binding-protein-dependent transport systems inner membrane component Oant_0296 138 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 153008671 Common - NAD-dependent epimerase/dehydratase Oant_1340 116 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153007803 Common - glyoxylate carboligase Oant_0458 221 COG3960 COG3960, Glyoxylate carboligase General function prediction only 153009158 Common - transport system permease protein Oant_1828 190 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 153009646 Common - MT-A70 family protein Oant_2318 25 COG4725 IME4, Transcriptional activator, adenine-specific DNA methyltransferase Signal transduction mechanisms / Transcription 153007642 Common - ABC transporter related Oant_0297 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 153008102 Common - two component transcriptional regulator, winged helix family Oant_0766 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153009261 Common - major facilitator superfamily MFS_1 Oant_1931 122 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153008703 Common - WD-repeat family protein Oant_1372 38 COG2319 COG2319, FOG: WD40 repeat General function prediction only 153009981 Common - Glutathione S-transferase domain protein Oant_2655 99 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153007791 Common - TRAP dicarboxylate transporter- DctP subunit Oant_0446 97 COG4663 FcbT1, TRAP-type mannitol/chloroaromatic compound transport system, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 153009532 Common - hypothetical protein Oant_2202 2 None None None 153008953 Common - ubiquinol-cytochrome c reductase, iron-sulfur subunit Oant_1623 100 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 153007747 Common - SCP-like extracellular Oant_0402 54 COG2340 COG2340, Uncharacterized protein with SCP/PR1 domains Function unknown 153007690 Common - binding-protein-dependent transport systems inner membrane component Oant_0345 97 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153009286 Common - ribosomal protein L3 Oant_1956 217 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 153007864 Common - Polyprenyl synthetase Oant_0519 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 153008337 Common - protein of unknown function DUF188 Oant_1002 97 COG1671 COG1671, Uncharacterized protein conserved in bacteria Function unknown 153008963 Common - chromate transporter, chromate ion transporter (CHR) family Oant_1633 116 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 153008316 Common - MIP family channel protein Oant_0981 121 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 153008661 Common - Dihydrodipicolinate reductase Oant_1330 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 153009445 Common - dihydropteroate synthase Oant_2115 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 153009766 Common - HupE/UreJ protein Oant_2438 44 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 153008857 Pathogen - hypothetical protein Oant_1527 1 None None None 153008044 Common - IstB domain protein ATP-binding protein Oant_0707 102 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 153009417 Common - glutamine synthetase, type I Oant_2087 228 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 153009978 Common - protein of unknown function DUF161 Oant_2652 58 COG1284 COG1284, Uncharacterized conserved protein Function unknown 153007963 Common - hypothetical protein Oant_0619 6 COG4226 HicB, Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters Function unknown 153008847 Pathogen - hypothetical protein Oant_1517 1 None None None 153009187 Common - protein of unknown function DUF1234 Oant_1857 55 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 153008607 Common - regulatory protein IclR Oant_1276 96 COG1414 IclR, Transcriptional regulator Transcription 153007546 Common - sulfate adenylyltransferase, large subunit Oant_0201 249 COG2895 CysN, GTPases - Sulfate adenylate transferase subunit 1 Inorganic ion transport and metabolism 153009037 Common - RNA-directed DNA polymerase (Reverse transcriptase) Oant_1707 94 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 153009316 Common - recA protein Oant_1986 244 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 153009903 Common - phosphoribosylformylglycinamidine cyclo-ligase Oant_2576 228 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 153007686 Common - efflux transporter, RND family, MFP subunit Oant_0341 163 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 153008685 Common - 2,3,4,5-tetrahydropyridine-2,6-dicarboxylate N-succinyltransferase Oant_1354 139 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 153008057 Common - peptidase A24A prepilin type IV Oant_0721 22 COG4960 CpaA, Flp pilus assembly protein, protease CpaA Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153008237 Common - Serine-type D-Ala-D-Ala carboxypeptidase Oant_0902 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 153009177 Pathogen - hypothetical protein Oant_1847 1 None None None 153009471 Common - Threonyl/alanyl tRNA synthetase SAD Oant_2141 202 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 153009848 Common - hypothetical protein Oant_2521 27 None None None 153008600 Common - malate synthase G Oant_1269 83 COG2225 AceB, Malate synthase Energy production and conversion 153008463 Common - protein of unknown function DUF336 Oant_1129 28 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 153009074 Common - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase Oant_1744 208 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 153010032 Common - death-on-curing family protein Oant_2706 61 COG3654 Doc, Prophage maintenance system killer protein General function prediction only 153008725 Common - binding-protein-dependent transport systems inner membrane component Oant_1394 187 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 153007753 Common - two component transcriptional regulator, LuxR family Oant_0408 178 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 153007983 Common - metallophosphoesterase Oant_0641 37 COG1409 Icc, Predicted phosphohydrolases General function prediction only 153008457 Common - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase Oant_1123 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 153009911 Common - Glutathione S-transferase domain protein Oant_2584 65 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153009273 Common - ribosomal protein L11 Oant_1943 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 153008270 Common - hypothetical protein Oant_0935 16 COG3686 COG3686, Predicted membrane protein Function unknown 153008441 Common - transcriptional regulator, MarR family Oant_1107 104 COG1846 MarR, Transcriptional regulators Transcription 153009218 Common - uroporphyrin-III C-methyltransferase Oant_1888 203 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 153007473 Common - Lysine exporter protein (LYSE/YGGA) Oant_0128 119 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 153008816 Common - phage late control D family protein Oant_1485 16 COG3500 COG3500, Phage protein D General function prediction only 153009669 Common - stationary-phase survival protein SurE Oant_2341 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 153008183 Common - FxsA cytoplasmic membrane protein Oant_0847 68 COG3030 FxsA, Protein affecting phage T7 exclusion by the F plasmid General function prediction only 153007586 Pathogen - hypothetical protein Oant_0241 1 None None None 153009013 Common - carbamoyl-phosphate synthase, small subunit Oant_1683 236 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 153007955 Common - NAD-dependent epimerase/dehydratase Oant_0610 233 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153008728 Common - glucose-methanol-choline oxidoreductase Oant_1397 92 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 153009620 Common - phage tail X family protein Oant_2290 22 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 153009190 Common - protein-export membrane protein SecD Oant_1860 203 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 153008355 Common - polysaccharide biosynthesis protein Oant_1020 36 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 153007494 Common - hypothetical protein Oant_0149 10 COG5502 COG5502, Uncharacterized conserved protein Function unknown 153008586 Common - TonB system transport protein ExbD type-1 Oant_1255 137 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 153007382 Common - acyl-CoA dehydrogenase domain protein Oant_0037 170 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153008646 Common - conserved hypothetical 25.1 kDa protein in CobV 5'region (orf1) Oant_1315 50 COG3577 COG3577, Predicted aspartyl protease General function prediction only 153009957 Common - hypothetical protein Oant_2630 43 COG3216 COG3216, Uncharacterized protein conserved in bacteria Function unknown 153007374 Common - ribosomal protein S1 Oant_0029 218 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 153009084 Common - DNA ligase, NAD-dependent Oant_1754 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 153008794 Common - extracellular solute-binding protein family 1 Oant_1463 105 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 153007539 Common - methylated-DNA--protein-cysteine methyltransferase Oant_0194 215 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 153008255 Common - putative transcriptional regulator, MerR family Oant_0920 144 COG0789 SoxR, Predicted transcriptional regulators Transcription 153009370 Common - protein of unknown function DUF1009 Oant_2040 45 COG3494 COG3494, Uncharacterized protein conserved in bacteria Function unknown 153007926 Common - Cytochrome c oxidase subunit II Oant_0581 149 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 153009041 Common - ferredoxin Oant_1711 135 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 153009028 Common - CsbD family protein Oant_1698 56 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 153007617 Common - Alcohol dehydrogenase GroES domain protein Oant_0272 209 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 153007667 Common - maf protein Oant_0322 199 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 153007603 Pathogen - hypothetical protein Oant_0258 1 None None None 153007384 Common - Carbamoyl-phosphate synthase L chain ATP-binding Oant_0039 235 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 153008267 Common - succinyl-CoA synthetase, alpha subunit Oant_0932 215 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 153007636 Common - ABC transporter related Oant_0291 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153007574 Common - DnaB domain protein helicase domain protein Oant_0229 214 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 153009021 Common - protein of unknown function UPF0153 Oant_1691 74 COG2983 COG2983, Uncharacterized conserved protein Function unknown 153007991 Common - TraC family protein Oant_0649 7 None None None 153009865 Common - Arginyltransferase Oant_2538 85 COG2935 COG2935, Putative arginyl-tRNA:protein arginylyltransferase Posttranslational modification, protein turnover, chaperones 153008753 Common - 2-keto-3-deoxy-galactonokinase Oant_1422 41 COG3734 DgoK, 2-keto-3-deoxy-galactonokinase Carbohydrate transport and metabolism 153009326 Common - glutamate racemase Oant_1996 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 153009263 Common - ferripyochelin-binding protein, hypothetical Oant_1933 219 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 153007981 Common - binding-protein-dependent transport systems inner membrane component Oant_0639 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153009833 Common - polysaccharide export protein Oant_2506 107 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 153010045 Common - dTDP-4-dehydrorhamnose 3,5-epimerase Oant_2720 166 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 153008553 Common - tRNA(Ile)-lysidine synthetase Oant_1222 127 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 153007782 Common - carboxynorspermidine decarboxylase Oant_0437 55 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 153008929 Common - 2-isopropylmalate synthase Oant_1599 211 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 153009130 Common - phosphoserine phosphatase SerB Oant_1800 152 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 153009728 Common - transcriptional regulator, HxlR family Oant_2400 148 COG1733 COG1733, Predicted transcriptional regulators Transcription 153008904 Common - hypothetical protein Oant_1574 46 COG2388 COG2388, Predicted acetyltransferase General function prediction only 153009961 Common - putative transcriptional regulator, Crp/Fnr family Oant_2634 143 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153007368 Common - recombination protein RecR Oant_0023 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 153008644 Common - GCN5-related N-acetyltransferase Oant_1313 24 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 153008886 Common - heat shock protein DnaJ domain protein Oant_1556 3 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 153009304 Common - ribosomal protein L30 Oant_1974 84 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 153007957 Common - DSBA oxidoreductase Oant_0612 96 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 153009351 Common - ATP-dependent Clp protease, ATP-binding subunit clpA Oant_2021 227 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 153009950 Common - hypothetical protein Oant_2623 31 COG1896 COG1896, Predicted hydrolases of HD superfamily General function prediction only 153009787 Common - carbohydrate kinase FGGY Oant_2460 176 COG0554 GlpK, Glycerol kinase Energy production and conversion 153009543 Pathogen - hypothetical protein Oant_2213 1 None None None 153007394 Common - Cytochrome o ubiquinol oxidase subunit I Oant_0049 166 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 153008243 Pathogen - hypothetical protein Oant_0908 1 None None None 153008118 Common - Mg chelatase, subunit ChlI Oant_0782 194 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 153007629 Common - glycine oxidase ThiO Oant_0284 93 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153009598 Common - ribonuclease, Rne/Rng family Oant_2268 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 153007893 Common - hemolysin A Oant_0548 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 153008326 Common - hypothetical protein Oant_0991 9 COG4093 COG4093, Uncharacterized protein conserved in bacteria Function unknown 153009633 Common - hypothetical protein Oant_2303 3 None None None 153009496 Common - secretion protein HlyD family protein Oant_2166 95 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 153007611 Common - putative transcriptional regulator, Crp/Fnr family Oant_0266 89 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153008136 Common - ribosomal protein L20 Oant_0800 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 153007401 Pathogen - hypothetical protein Oant_0056 2 None None None 153008849 Common - hypothetical protein Oant_1519 2 None None None 153007772 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Oant_0427 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 153008711 Common - diguanylate cyclase/phosphodiesterase Oant_1380 179 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 153008517 Common - glucose sorbosone dehydrogenase Oant_1186 124 COG2133 COG2133, Glucose/sorbosone dehydrogenases Carbohydrate transport and metabolism 153010060 Common - glycosyltransferase-like protein Oant_2736 63 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 153009612 Common - DNA-directed DNA polymerase Oant_2282 181 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 153009873 Common - monooxygenase FAD-binding Oant_2546 61 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 153009713 Common - Glutathione S-transferase domain protein Oant_2385 92 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153009139 Common - hypothetical protein Oant_1809 6 None None None 153007408 Common - hypothetical protein Oant_0063 30 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 153009048 Common - ABC transporter related Oant_1718 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153009402 Common - nitrogen metabolism transcriptional regulator, NtrC, Fis Family Oant_2072 219 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 153009205 Common - Adenosylcobinamide-phosphate guanylyltransferase Oant_1875 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 153008523 Common - protein of unknown function DUF710 Oant_1192 21 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 153008223 Common - hypothetical protein Oant_0887 2 None None None 153008781 Common - hypothetical protein Oant_1450 5 None None None 153009534 Common - ATP-dependent protease La Oant_2204 224 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 153008920 Common - hypothetical protein Oant_1590 18 COG5345 COG5345, Uncharacterized protein conserved in bacteria Function unknown 153009769 Common - urease, alpha subunit Oant_2441 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 153009529 Common - single-strand binding protein Oant_2199 211 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 153010070 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Oant_2746 56 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 153007514 Common - ABC transporter related Oant_0169 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 153010018 Pathogen - conserved hypothetical membrane spanning protein Oant_2692 2 None None None 153007939 Common - Transposase and inactivated derivatives-like protein Oant_0594 82 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 153007854 Common - hypothetical protein Oant_0509 14 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153007503 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase Oant_0158 216 COG0281 SfcA, Malic enzyme Energy production and conversion 153007692 Common - dihydropyrimidinase Oant_0347 205 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 153009990 Common - (Glutamate--ammonia-ligase) adenylyltransferase Oant_2664 119 COG1391 GlnE, Glutamine synthetase adenylyltransferase Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms 153008395 Common - peptidase M23B Oant_1061 119 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 153007544 Common - aminotransferase class-III Oant_0199 236 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 153008877 Common - AAA ATPase central domain protein Oant_1547 238 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 153008033 Common - Ureidoglycolate hydrolase Oant_0694 35 COG3194 DAL3, Ureidoglycolate hydrolase Nucleotide transport and metabolism 153009760 Common - Succinylglutamate desuccinylase/aspartoacylase Oant_2432 46 COG3608 COG3608, Predicted deacylase General function prediction only 153008632 Common - transcriptional regulator, XRE family Oant_1301 65 COG1476 COG1476, Predicted transcriptional regulators Transcription 153010053 Common - transposase IS66 Oant_2728 63 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009056 Common - glycoside hydrolase family 25 Oant_1726 45 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 153009296 Common - ribosomal protein L14 Oant_1966 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 153008439 Common - ATP synthase F1, beta subunit Oant_1105 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 153008042 Common - Integrase catalytic region Oant_0704 79 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 153008066 Common - Leucyl aminopeptidase Oant_0730 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 153009917 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Oant_2590 202 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 153008695 Common - protein of unknown function DUF1486 Oant_1364 12 COG5485 COG5485, Predicted ester cyclase General function prediction only 153009824 Common - 5'-nucleotidase, lipoprotein e(P4) family Oant_2497 25 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 153009200 Common - 3-hydroxyisobutyrate dehydrogenase Oant_1870 166 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 153007657 Common - ABC transporter related Oant_0312 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153007849 Common - NUDIX hydrolase Oant_0504 120 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 153008639 Common - hypothetical protein Oant_1308 2 None None None 153008881 Pathogen - hypothetical protein Oant_1551 1 None None None 153009772 Common - Urease accessory protein UreD Oant_2444 78 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 153010029 Common - GntR domain protein Oant_2703 129 COG2186 FadR, Transcriptional regulators Transcription 153008199 Common - DNA polymerase III, delta subunit Oant_0863 58 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 153009104 Common - transcriptional regulator, TetR family Oant_1774 26 COG1309 AcrR, Transcriptional regulator Transcription 153007934 Common - hydroxymethylbutenyl pyrophosphate reductase Oant_0589 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 153009465 Common - molybdopterin binding domain protein Oant_2135 165 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 153008406 Common - pyridoxal kinase Oant_1072 59 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 153008653 Common - hypothetical protein Oant_1322 30 COG3247 HdeD, Uncharacterized conserved protein Function unknown 153009127 Common - protease Do Oant_1797 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 153008271 Common - Lysine exporter protein (LYSE/YGGA) Oant_0936 121 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 153008779 Common - FMN-dependent alpha-hydroxy acid dehydrogenase Oant_1448 121 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 153009889 Common - conserved hypothetical transmembrane signal peptide protein Oant_2562 16 COG5455 COG5455, Predicted integral membrane protein Function unknown 153008407 Common - hypothetical protein Oant_1073 18 COG4923 COG4923, Uncharacterized conserved protein Function unknown 153008620 Common - binding-protein-dependent transport systems inner membrane component Oant_1289 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153009327 Common - aldo/keto reductase Oant_1997 197 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 153007777 Common - transcriptional regulator, TetR family Oant_0432 17 COG1309 AcrR, Transcriptional regulator Transcription 153009702 Common - Alcohol dehydrogenase zinc-binding domain protein Oant_2374 190 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 153009162 Common - Monosaccharide-transporting ATPase Oant_1832 113 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153008465 Common - helicase domain protein Oant_1131 67 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 153009951 Common - hypothetical protein Oant_2624 15 COG5350 COG5350, Predicted protein tyrosine phosphatase General function prediction only 153009756 Common - TRAP transporter, 4TM/12TM fusion protein Oant_2428 123 COG4666 COG4666, TRAP-type uncharacterized transport system, fused permease components General function prediction only 153008291 Common - OsmC family protein Oant_0956 64 COG1764 OsmC, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 153008309 Common - putative metalloendopeptidase, glycoprotease family Oant_0974 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 153009004 Common - dTDP-4-dehydrorhamnose reductase Oant_1674 72 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153008897 Common - putative ammonia monooxygenase Oant_1567 49 COG3180 AbrB, Putative ammonia monooxygenase General function prediction only 153008808 Common - acyl carrier protein Oant_1477 7 None None None 153009422 Common - ribose 5-phosphate isomerase Oant_2092 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 153009653 Common - hypothetical protein Oant_2325 2 None None None 153009608 Common - GCN5-related N-acetyltransferase Oant_2278 28 COG0456 RimI, Acetyltransferases General function prediction only 153008194 Common - tRNA modification GTPase TrmE Oant_0858 219 COG0486 ThdF, Predicted GTPase General function prediction only 153008387 Common - GCN5-related N-acetyltransferase Oant_1053 30 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153009899 Pathogen - hypothetical protein Oant_2572 2 None None None 153008801 Common - arginase Oant_1470 138 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 153009931 Common - SurA domain protein Oant_2604 78 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 153007561 Pathogen - hypothetical protein Oant_0216 1 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 153008596 Common - glutamine amidotransferase class-II Oant_1265 61 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 153010008 Common - Peptidoglycan-binding domain 1 protein Oant_2682 13 None None None 153007674 Common - hypothetical protein Oant_0329 4 None None None 153008627 Common - diguanylate cyclase Oant_1296 175 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153009254 Common - protein of unknown function DUF192 Oant_1924 86 COG1430 COG1430, Uncharacterized conserved protein Function unknown 153008165 Common - Phosphoenolpyruvate carboxykinase (ATP) Oant_0829 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 153007482 Common - DNA polymerase I Oant_0137 217 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 153008157 Common - histidine kinase Oant_0821 219 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 153008615 Common - transcriptional regulator, LysR family Oant_1284 177 COG0583 LysR, Transcriptional regulator Transcription 153007835 Common - OmpA/MotB domain protein Oant_0490 169 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 153009526 Common - phosphonate metabolism PhnG Oant_2196 32 COG3624 PhnG, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 153008544 Common - Holliday junction DNA helicase RuvB Oant_1213 230 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 153008718 Common - homoserine dehydrogenase NAD-binding Oant_1387 43 COG4091 COG4091, Predicted homoserine dehydrogenase Amino acid transport and metabolism 153009066 Common - S-adenosyl-methyltransferase MraW Oant_1736 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 153007685 Common - integral membrane sensor signal transduction histidine kinase Oant_0340 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153009442 Common - ferredoxin Oant_2112 78 COG0633 Fdx, Ferredoxin Energy production and conversion 153009910 Common - ribonuclease T2 Oant_2583 52 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 153009987 Common - protein of unknown function DUF6 transmembrane Oant_2661 93 COG2962 RarD, Predicted permeases General function prediction only 153009920 Common - protein of unknown function DUF306 Meta and HslJ Oant_2593 38 COG3126 COG3126, Uncharacterized protein conserved in bacteria Function unknown 153007362 Common - 3-deoxy-D-manno-octulosonate cytidylyltransferase Oant_0017 144 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 153010072 Common - phosphoribulokinase/uridine kinase Oant_2748 102 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 153007857 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Oant_0512 173 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 153009642 Common - hypothetical protein Oant_2314 10 None None None 153008559 Common - phosphoserine aminotransferase Oant_1228 64 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 153008722 Common - ribosomal protein S21 Oant_1391 39 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 153009651 Pathogen - hypothetical protein Oant_2323 1 None None None 153007759 Common - polysaccharide deacetylase Oant_0414 106 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 153008365 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Oant_1030 202 COG0388 COG0388, Predicted amidohydrolase General function prediction only 153009626 Common - hypothetical protein Oant_2296 2 None None None 153008059 Common - type II and III secretion system protein Oant_0723 138 COG4964 CpaC, Flp pilus assembly protein, secretin CpaC Intracellular trafficking and secretion 153009416 Common - ATP12 ATPase Oant_2086 33 COG5387 COG5387, Chaperone required for the assembly of the mitochondrial F1-ATPase Posttranslational modification, protein turnover, chaperones 153008192 Common - transcription termination factor Rho Oant_0856 212 COG1158 Rho, Transcription termination factor Transcription 153010030 Common - Mg2 transporter protein CorA family protein Oant_2704 154 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 153009018 Common - RNA polymerase, sigma 70 subunit, RpoD Oant_1688 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 153008566 Common - Rhodanese domain protein Oant_1235 32 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 153007644 Common - Substrate-binding region of ABC-type glycine betaine transport system Oant_0299 80 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 153009271 Common - preprotein translocase, SecE subunit Oant_1941 31 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 153007585 Common - putative major head protein/prohead protease Oant_0240 10 None None None 153007806 Common - Hydroxypyruvate reductase Oant_0461 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 153007988 Pathogen - hypothetical protein Oant_0646 1 None None None 153008848 Pathogen - hypothetical protein Oant_1518 1 None None None 153008908 Common - protein of unknown function DUF6 transmembrane Oant_1578 155 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 153009934 Common - peptidase M23B Oant_2607 189 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 153009916 Common - excinuclease ABC, C subunit Oant_2589 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 153008921 Common - Ribosomal small subunit Rsm22 Oant_1591 17 COG5459 COG5459, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 153008292 Common - Ubiquinone biosynthesis hydroxylase, UbiH/UbiF/VisC/COQ6 family Oant_0957 134 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 153007917 Common - acyl carrier protein Oant_0572 206 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153009578 Common - TfoX domain protein Oant_2248 29 COG3070 TfoX, Regulator of competence-specific genes Transcription 153009476 Common - Acetyl-CoA hydrolase Oant_2146 96 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 153008819 Common - phage tail tape measure protein, TP901 family Oant_1488 31 COG5283 COG5283, Phage-related tail protein Function unknown 153008572 Pathogen - hypothetical protein Oant_1241 1 None None None 153007751 Common - hypothetical protein Oant_0406 9 None None None 153008676 Common - methionyl-tRNA formyltransferase Oant_1345 216 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 153008340 Common - short-chain dehydrogenase/reductase SDR Oant_1005 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 153008041 Common - hypothetical protein Oant_0703 5 COG0622 COG0622, Predicted phosphoesterase General function prediction only 153009214 Common - transcriptional regulator, TetR family Oant_1884 39 COG1309 AcrR, Transcriptional regulator Transcription 153009706 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_2378 41 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 153008691 Common - GTP-binding protein HSR1-related Oant_1360 180 COG0218 COG0218, Predicted GTPase General function prediction only 153009488 Common - GTP cyclohydrolase I Oant_2158 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 153007868 Pathogen - hypothetical protein Oant_0523 1 None None None 153009562 Common - protein of unknown function DUF6 transmembrane Oant_2232 46 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 153008314 Common - protein of unknown function DUF1332 Oant_0979 36 COG4103 COG4103, Uncharacterized protein conserved in bacteria Function unknown 153008516 Common - Fructose-bisphosphate aldolase Oant_1185 33 COG3588 COG3588, Fructose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 153008493 Common - hypothetical protein Oant_1161 38 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 153009029 Common - Choloylglycine hydrolase Oant_1699 53 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 153008282 Common - 3-isopropylmalate dehydratase, large subunit Oant_0947 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 153008175 Common - 20S proteasome A and B subunits Oant_0839 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 153009196 Pathogen - hypothetical protein Oant_1866 1 None None None 153008810 Pathogen - hypothetical protein Oant_1479 2 None None None 153009010 Common - acyltransferase 3 Oant_1680 66 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 153008584 Pathogen - hypothetical protein Oant_1253 2 None None None 153008272 Common - hypothetical protein Oant_0937 5 None None None 153009236 Common - extracellular solute-binding protein family 5 Oant_1906 192 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153008378 Common - MATE efflux family protein Oant_1044 150 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153009688 Common - Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase Oant_2360 118 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 153009671 Common - Sec-independent protein translocase, TatC subunit Oant_2343 204 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 153007785 Common - MATE efflux family protein Oant_0440 146 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153008621 Common - binding-protein-dependent transport systems inner membrane component Oant_1290 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153008783 Common - efflux transporter, RND family, MFP subunit Oant_1452 146 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 153009189 Common - potassium efflux system protein Oant_1859 204 COG4651 RosB, Kef-type K+ transport system, predicted NAD-binding component Inorganic ion transport and metabolism 153009599 Common - aminotransferase class I and II Oant_2269 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153007357 Common - binding-protein-dependent transport systems inner membrane component Oant_0012 220 COG4239 COG4239, ABC-type uncharacterized transport system, permease component General function prediction only 153009284 Common - translation elongation factor Tu Oant_1954 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 153008861 Common - protein of unknown function DUF159 Oant_1531 112 COG2135 COG2135, Uncharacterized conserved protein Function unknown 153008826 Common - virulence-associated protein Oant_1495 8 None None None 153010074 Common - hypothetical protein Oant_2750 13 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 153007666 Common - protein of unknown function DUF329 Oant_0321 39 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 153007476 Common - penicillin-binding protein, 1A family Oant_0131 201 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 153007933 Common - Surfeit locus 1 family protein Oant_0588 56 COG3346 COG3346, Uncharacterized conserved protein Function unknown 153009786 Common - major facilitator superfamily MFS_1 Oant_2459 103 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153008092 Common - protein of unknown function UPF0054 Oant_0756 110 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 153008836 Common - phage portal protein, lambda family Oant_1505 34 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 153009629 Common - Baseplate J family protein Oant_2299 32 COG3948 COG3948, Phage-related baseplate assembly protein General function prediction only 153008161 Common - PTS system fructose subfamily IIA component Oant_0825 96 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 153009761 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Oant_2433 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 153009718 Common - BolA family protein Oant_2390 79 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 153010010 Pathogen - hypothetical protein Oant_2684 3 None None None 153007670 Common - uncharacterised conserved protein UCP032146 Oant_0325 31 COG5328 COG5328, Uncharacterized protein conserved in bacteria Function unknown 153008701 Common - protein of unknown function DUF1287 Oant_1370 17 COG3738 COG3738, Uncharacterized protein conserved in bacteria Function unknown 153009587 Common - aminotransferase class V Oant_2257 232 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 153007778 Common - Oxidoreductase FAD-binding domain protein Oant_0433 122 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 153009843 Common - putative transcriptional regulator, MerR family Oant_2516 91 COG0789 SoxR, Predicted transcriptional regulators Transcription 153009035 Pathogen - hypothetical protein Oant_1705 2 None None None 153007385 Common - Hydroxymethylglutaryl-CoA lyase Oant_0040 103 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 153008050 Pathogen - hypothetical protein Oant_0713 1 None None None 153008702 Pathogen - hypothetical protein Oant_1371 1 None None None 153007459 Common - response regulator receiver protein Oant_0114 27 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 153008394 Pathogen - hypothetical protein Oant_1060 3 None None None 153009995 Common - cytochrome c-type biogenesis protein CcmF Oant_2669 138 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 153009248 Common - ABC transporter related Oant_1918 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153009539 Common - TrkA-N domain protein Oant_2209 151 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 153008126 Common - chaperone protein DnaK Oant_0790 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 153008070 Common - Glyoxylate reductase Oant_0734 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 153008628 Common - hypothetical protein Oant_1297 11 None None None 153008944 Common - hypothetical protein Oant_1614 18 COG3811 COG3811, Uncharacterized protein conserved in bacteria Function unknown 153007697 Common - binding-protein-dependent transport systems inner membrane component Oant_0352 193 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153008451 Common - Extracellular ligand-binding receptor Oant_1117 145 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 153007974 Pathogen - hypothetical protein Oant_0631 1 None None None 153009072 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Oant_1742 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 153009859 Common - transcriptional regulator, MarR family Oant_2532 22 COG1846 MarR, Transcriptional regulators Transcription 153009318 Common - Antibiotic biosynthesis monooxygenase Oant_1988 37 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 153009792 Common - transposase IS3/IS911 family protein Oant_2465 53 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009731 Common - ABC transporter related Oant_2403 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153007834 Common - hypothetical protein Oant_0489 44 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153008019 Common - TrbL/VirB6 plasmid conjugal transfer protein Oant_0680 29 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 153009062 Common - N-acetylmuramoyl-L-alanine amidase family 2 Oant_1732 114 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 153008606 Common - succinic semialdehyde dehydrogenase Oant_1275 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153007946 Common - hypothetical protein Oant_0601 18 COG5397 COG5397, Uncharacterized conserved protein Function unknown 153007822 Common - hypothetical protein Oant_0477 24 COG3826 COG3826, Uncharacterized protein conserved in bacteria Function unknown 153008000 Common - Transketolase central region Oant_0661 170 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 153007552 Pathogen - hypothetical protein Oant_0207 1 None None None 153009939 Pathogen - hypothetical protein Oant_2612 2 None None None 153007492 Common - ATP-dependent helicase HrpB Oant_0147 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 153007433 Common - Lysine exporter protein (LYSE/YGGA) Oant_0088 117 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 153007594 Common - hypothetical protein Oant_0249 3 None None None 153008501 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Oant_1169 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 153010015 Pathogen - conserved hypothetical cytosolic protein Oant_2689 2 None None None 153008382 Common - Agmatine deiminase Oant_1048 87 COG2957 COG2957, Peptidylarginine deiminase and related enzymes Amino acid transport and metabolism 153008805 Common - Domain of unknown function DUF1839 Oant_1474 7 None None None 153009517 Common - phosphonate ABC transporter, ATPase subunit Oant_2187 249 COG3638 COG3638, ABC-type phosphate/phosphonate transport system, ATPase component Inorganic ion transport and metabolism 153007744 Common - 2-deoxycytidine 5-triphosphate deaminase Oant_0399 23 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 153009850 Common - SmpA/OmlA domain protein Oant_2523 34 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 153007428 Common - transcriptional regulator, MarR family Oant_0083 129 COG1846 MarR, Transcriptional regulators Transcription 153008423 Common - Fmu (Sun) domain protein Oant_1089 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 153008748 Common - ABC transporter related Oant_1417 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153007723 Common - extracellular solute-binding protein family 3 Oant_0378 103 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153008470 Common - short-chain dehydrogenase/reductase SDR Oant_1136 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153008648 Common - ubiquinone/menaquinone biosynthesis methyltransferase Oant_1317 214 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153008613 Common - CMP/dCMP deaminase zinc-binding Oant_1282 173 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 153009342 Common - putative transcriptional regulator, MerR family Oant_2012 103 COG0789 SoxR, Predicted transcriptional regulators Transcription 153008014 Common - VIRB2 type IV secretion fmaily protein Oant_0675 8 COG3838 VirB2, Type IV secretory pathway, VirB2 components (pilins) Intracellular trafficking and secretion 153008481 Pathogen - hypothetical protein Oant_1148 1 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153009440 Common - lipoprotein, hypothetical Oant_2110 25 COG3218 COG3218, ABC-type uncharacterized transport system, auxiliary component General function prediction only 153008531 Common - protein of unknown function DUF28 Oant_1200 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 153009826 Common - putative agmatinase Oant_2499 131 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 153009553 Pathogen - hypothetical protein Oant_2223 1 None None None 153008027 Common - hypothetical protein Oant_0688 3 None None None 153007738 Common - GcrA cell cycle regulator Oant_0393 33 COG5352 COG5352, Uncharacterized protein conserved in bacteria Function unknown 153009220 Common - aminotransferase class I and II Oant_1890 222 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 153009527 Common - transcriptional regulator, GntR family Oant_2197 143 COG2188 PhnF, Transcriptional regulators Transcription 153009099 Common - AsmA family protein Oant_1769 23 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 153007540 Common - hypothetical protein Oant_0195 4 None None None 153008863 Common - protein of unknown function DUF497 Oant_1533 9 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 153008509 Pathogen - hypothetical protein Oant_1178 2 None None None 153009738 Common - proton-translocating NADH-quinone oxidoreductase, chain N Oant_2410 208 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 153008588 Common - hypothetical protein Oant_1257 23 COG3698 COG3698, Predicted periplasmic protein Function unknown 153008079 Common - Polyribonucleotide nucleotidyltransferase Oant_0743 240 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 153009611 Common - hypothetical protein Oant_2281 5 None None None 153008186 Common - dephospho-CoA kinase Oant_0850 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 153007703 Common - PfkB domain protein Oant_0358 132 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153009395 Common - lipoic acid synthetase Oant_2065 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 153007796 Common - Xanthine dehydrogenase small subunit Oant_0451 122 COG4630 XdhA, Xanthine dehydrogenase, iron-sulfur cluster and FAD-binding subunit A Nucleotide transport and metabolism 153009631 Common - PAAR repeat-containing protein Oant_2301 21 COG4104 COG4104, Uncharacterized conserved protein Function unknown 153007829 Common - protein of unknown function DUF1228 Oant_0484 81 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 153007447 Common - hypothetical protein Oant_0102 30 None None None 153009691 Common - hypothetical protein Oant_2363 53 COG3577 COG3577, Predicted aspartyl protease General function prediction only 153007735 Common - polysaccharide deacetylase Oant_0390 14 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 153008148 Common - tryptophan synthase, alpha subunit Oant_0812 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 153008067 Common - transcriptional regulator, MarR family Oant_0731 16 COG1846 MarR, Transcriptional regulators Transcription 153008258 Common - Hydroxyacylglutathione hydrolase Oant_0923 203 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 153009385 Common - 2-dehydro-3-deoxyphosphooctonate aldolase Oant_2055 185 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 153008699 Common - oxidoreductase molybdopterin binding Oant_1368 120 COG2041 COG2041, Sulfite oxidase and related enzymes General function prediction only 153007866 Common - glycyl-tRNA synthetase, alpha subunit Oant_0521 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 153009083 Common - DNA repair protein RecN Oant_1753 199 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 153009170 Common - binding-protein-dependent transport systems inner membrane component Oant_1840 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153009525 Common - phosphonate metabolism Oant_2195 42 COG3625 PhnH, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 153007421 Common - hypothetical protein Oant_0076 3 None None None 153008965 Common - lipoprotein, hypothetical Oant_1635 9 None None None 153009118 Pathogen - hypothetical protein Oant_1788 1 None None None 153009144 Pathogen - hypothetical protein Oant_1814 1 None None None 153009371 Common - lipid-A-disaccharide synthase Oant_2041 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 153009113 Pathogen - putative transcriptional regulator, MerR family Oant_1783 1 COG0789 SoxR, Predicted transcriptional regulators Transcription 153008538 Common - Sel1 domain protein repeat-containing protein Oant_1207 101 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 153009715 Pathogen - hypothetical protein Oant_2387 2 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 153007813 Common - cytochrome c oxidase, cbb3-type, subunit II Oant_0468 82 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 153009940 Common - protein of unknown function DUF159 Oant_2613 104 COG2135 COG2135, Uncharacterized conserved protein Function unknown 153008735 Common - putative transcriptional regulator, AsnC family Oant_1404 125 COG1522 Lrp, Transcriptional regulators Transcription 153007745 Common - transcriptional regulator, AraC family Oant_0400 87 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 153009241 Common - sugar fermentation stimulation protein Oant_1911 106 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 153009805 Common - TOBE domain protein Oant_2478 7 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153007481 Common - peptidase M20 Oant_0136 175 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 153008931 Common - metallophosphoesterase Oant_1601 46 COG1409 Icc, Predicted phosphohydrolases General function prediction only 153007846 Common - H+transporting two-sector ATPase C subunit Oant_0501 39 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 153009122 Common - Thymidylate synthase Oant_1792 144 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 153007518 Common - protein of unknown function DUF1150 Oant_0173 13 COG5568 COG5568, Uncharacterized small protein Function unknown 153009969 Common - Lytic transglycosylase catalytic Oant_2642 154 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 153008717 Common - NAD(P)(+) transhydrogenase (AB-specific) Oant_1386 123 COG1282 PntB, NAD/NADP transhydrogenase beta subunit Energy production and conversion 153008442 Common - nitrite reductase, copper-containing Oant_1108 66 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 153009894 Common - protein of unknown function DUF6 transmembrane Oant_2567 163 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 153007406 Common - hypothetical protein Oant_0061 12 None None None 153008817 Common - phage tail X family protein Oant_1486 2 COG5004 COG5004, P2-like prophage tail protein X General function prediction only 153009424 Common - glutathione-disulfide reductase Oant_2094 241 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 153007950 Common - DNA methylase N-4/N-6 domain protein Oant_0605 144 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 153007979 Common - extracellular solute-binding protein family 1 Oant_0637 98 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153009106 Common - hypothetical protein Oant_1776 2 None None None 153009464 Common - UspA domain protein Oant_2134 40 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 153007478 Common - porin Oant_0133 31 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 153007928 Common - protoheme IX farnesyltransferase Oant_0583 176 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 153007689 Common - binding-protein-dependent transport systems inner membrane component Oant_0344 156 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153007495 Common - two component transcriptional regulator, Fis family Oant_0150 214 COG4567 COG4567, Response regulator consisting of a CheY-like receiver domain and a Fis-type HTH domain Signal transduction mechanisms / Transcription 153007906 Common - Colicin V production protein Oant_0561 18 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 153009007 Common - NUDIX hydrolase Oant_1677 4 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 153008308 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Oant_0973 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 153009891 Common - lipoprotein, putative Oant_2564 3 None None None 153008899 Common - two component transcriptional regulator, winged helix family Oant_1569 214 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153007370 Common - hypothetical protein Oant_0025 7 None None None 153008397 Common - protein of unknown function DUF610 YibQ Oant_1063 62 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 153008242 Common - tyrosine recombinase XerD Oant_0907 225 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153009181 Common - SNARE associated Golgi protein Oant_1851 75 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 153008460 Common - Polyprenyl synthetase Oant_1126 240 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 153007859 Common - peptidase S49 Oant_0514 188 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153008896 Common - 3-demethylubiquinone-9 3-methyltransferase Oant_1566 43 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 153008875 Pathogen - hypothetical protein Oant_1545 1 None None None 153008668 Common - domain of unknown function DUF1730 Oant_1337 138 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 153007488 Common - GCN5-related N-acetyltransferase Oant_0143 93 COG2153 ElaA, Predicted acyltransferase General function prediction only 153007386 Common - Enoyl-CoA hydratase/isomerase Oant_0041 179 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 153008069 Common - alpha/beta hydrolase fold Oant_0733 171 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153008738 Common - transcriptional regulator, RpiR family Oant_1407 50 COG1737 RpiR, Transcriptional regulators Transcription 153008755 Common - sugar ABC transporter, periplasmic sugar-binding protein Oant_1424 92 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 153008774 Common - transcriptional regulator, XRE family Oant_1443 104 COG1396 HipB, Predicted transcriptional regulators Transcription 153009645 Common - hypothetical protein Oant_2317 2 None None None 153008542 Common - crossover junction endodeoxyribonuclease RuvC Oant_1211 197 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 153009840 Common - beta-lactamase domain protein Oant_2513 60 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 153007877 Common - diguanylate cyclase Oant_0532 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153009948 Common - dihydroorotase, multifunctional complex type Oant_2621 211 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 153009975 Common - aminotransferase class I and II Oant_2648 223 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 153008285 Common - GCN5-related N-acetyltransferase Oant_0950 8 COG0456 RimI, Acetyltransferases General function prediction only 153009085 Common - hypothetical protein Oant_1755 35 COG5587 COG5587, Uncharacterized conserved protein Function unknown 153009849 Common - Ubiquinol-cytochrome C chaperone Oant_2522 22 COG5452 COG5452, Uncharacterized conserved protein Function unknown 153009060 Pathogen - hypothetical protein Oant_1730 2 None None None 153008437 Common - ATP synthase F1, alpha subunit Oant_1103 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 153008650 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Oant_1319 233 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 153008778 Common - outer surface protein Oant_1447 27 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 153007699 Common - extracellular solute-binding protein family 1 Oant_0354 126 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153010050 Common - IS66 Orf2 family protein Oant_2725 49 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153008483 Common - phage integrase family protein Oant_1150 2 None None None 153009600 Common - peptidase M48 Ste24p Oant_2270 69 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 153009753 Common - protein of unknown function DUF900 hydrolase family protein Oant_2425 24 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 153008100 Common - lipoprotein, putative Oant_0764 5 None None None 153008252 Common - hypothetical protein Oant_0917 68 COG1738 COG1738, Uncharacterized conserved protein Function unknown 153010058 Common - hypothetical protein Oant_2734 12 None None None 153010005 Common - hypothetical protein Oant_2679 13 COG5436 COG5436, Predicted integral membrane protein Function unknown 153009724 Common - RNA-binding S4 domain protein Oant_2396 216 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 153007790 Common - TRAP dicarboxylate transporter, DctM subunit Oant_0445 126 COG4664 FcbT3, TRAP-type mannitol/chloroaromatic compound transport system, large permease component Secondary metabolites biosynthesis, transport, and catabolism 153008212 Common - short-chain dehydrogenase/reductase SDR Oant_0876 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153009771 Common - urease, gamma subunit Oant_2443 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 153009564 Common - molybdopterin-guanine dinucleotide biosynthesis protein B Oant_2234 104 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 153009251 Common - import inner membrane translocase subunit Tim44 Oant_1921 22 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 153007372 Common - conserved hypothetical protein 698 Oant_0027 114 COG2855 COG2855, Predicted membrane protein Function unknown 153009097 Common - FAD linked oxidase domain protein Oant_1767 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 153007619 Common - Alanine racemase Oant_0274 127 COG1609 PurR, Transcriptional regulators Transcription 153008869 Pathogen - hypothetical protein Oant_1539 1 None None None 153008249 Common - cobalt chelatase, pCobS small subunit Oant_0914 69 COG0714 COG0714, MoxR-like ATPases General function prediction only 153009491 Common - phage integrase family protein Oant_2161 15 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153009921 Common - Nucleoside-diphosphate kinase Oant_2594 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 153009298 Common - ribosomal protein L5 Oant_1968 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 153009989 Common - multi-sensor signal transduction histidine kinase Oant_2663 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153009330 Common - hypothetical protein Oant_2000 5 None None None 153009839 Common - short-chain dehydrogenase/reductase SDR Oant_2512 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153009830 Common - hypothetical protein Oant_2503 13 None None None 153008328 Common - histidinol-phosphate aminotransferase Oant_0993 237 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 153009607 Common - NADH:ubiquinone oxidoreductase 17.2 kD subunit Oant_2277 38 COG3761 COG3761, NADH:ubiquinone oxidoreductase 17.2 kD subunit Energy production and conversion 153007797 Common - Xanthine dehydrogenase molybdopterin binding subunit Oant_0452 110 COG4631 XdhB, Xanthine dehydrogenase, molybdopterin-binding subunit B Nucleotide transport and metabolism 153009054 Common - Auxin Efflux Carrier Oant_1724 98 COG0679 COG0679, Predicted permeases General function prediction only 153008035 Common - polysaccharide biosynthesis protein CapD Oant_0697 163 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153008156 Common - protein of unknown function UPF0079 Oant_0820 190 COG3178 COG3178, Predicted phosphotransferase related to Ser/Thr protein kinases General function prediction only 153009410 Common - hydrolase, TatD family Oant_2080 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 153010042 Common - Transposase and inactivated derivatives-like protein Oant_2717 47 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 153008260 Common - signal recognition particle-docking protein FtsY Oant_0925 246 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 153009673 Common - twin-arginine translocation protein, TatA/E family subunit Oant_2345 109 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 153009558 Common - hypothetical protein Oant_2228 28 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153008521 Common - transketolase Oant_1190 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 153008655 Common - Endonuclease/exonuclease/phosphatase Oant_1324 73 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 153009709 Common - protein of unknown function DUF1476 Oant_2381 25 COG5467 COG5467, Uncharacterized conserved protein Function unknown 153009046 Common - glycosyl transferase family 2 Oant_1716 104 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153008133 Common - phenylalanyl-tRNA synthetase, beta subunit Oant_0797 233 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 153008987 Common - protein of unknown function DUF486 Oant_1657 53 COG3169 COG3169, Uncharacterized protein conserved in bacteria Function unknown 153009429 Pathogen - proline-rich extensin Oant_2099 2 None None None 153009497 Common - ABC transporter related Oant_2167 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 153007554 Pathogen - hypothetical protein Oant_0209 1 None None None 153009551 Common - porin Oant_2221 14 None None None 153009864 Common - RDD domain containing protein Oant_2537 20 COG1714 COG1714, Predicted membrane protein/domain Function unknown 153010019 Common - AMP-dependent synthetase and ligase Oant_2693 225 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153009256 Common - serine O-acetyltransferase Oant_1926 206 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 153009788 Common - FAD dependent oxidoreductase Oant_2461 152 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 153008269 Common - 2-oxoglutarate dehydrogenase, E2 subunit, dihydrolipoamide succinyltransferase Oant_0934 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 153009617 Common - glycoside hydrolase family 24 Oant_2287 28 COG3772 COG3772, Phage-related lysozyme (muraminidase) General function prediction only 153007351 Common - UBA/THIF-type NAD/FAD binding protein Oant_0006 224 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 153010063 Common - ABC transporter related Oant_2739 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 153008229 Common - transcriptional regulator, XRE family Oant_0893 22 COG1476 COG1476, Predicted transcriptional regulators Transcription 153008163 Common - integral membrane sensor signal transduction histidine kinase Oant_0827 222 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153007964 Common - HicB family protein Oant_0621 26 COG4226 HicB, Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters Function unknown 153007501 Common - integral membrane protein MviN Oant_0156 189 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 153007776 Common - nicotinate-nucleotide pyrophosphorylase Oant_0431 206 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 153010031 Common - transcriptional regulator/antitoxin, MazE Oant_2705 17 COG2336 MazE, Growth regulator Signal transduction mechanisms 153009176 Pathogen - hypothetical protein Oant_1846 1 None None None 153008264 Common - AFG1-family ATPase Oant_0929 102 COG1485 COG1485, Predicted ATPase General function prediction only 153009960 Common - oxygen-independent coproporphyrinogen III oxidase Oant_2633 204 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 153007672 Common - hypothetical protein Oant_0327 22 None None None 153008724 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_1393 58 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 153008975 Common - transcriptional regulator, MarR family Oant_1645 41 COG1846 MarR, Transcriptional regulators Transcription 153008952 Common - ABC transporter related Oant_1622 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153007461 Common - diguanylate cyclase Oant_0116 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153008970 Common - protein of unknown function DUF526 Oant_1640 32 COG2960 COG2960, Uncharacterized protein conserved in bacteria Function unknown 153009433 Common - Citrate (Si)-synthase Oant_2103 193 COG0372 GltA, Citrate synthase Energy production and conversion 153009225 Pathogen - hypothetical protein Oant_1895 2 None None None 153008357 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Oant_1022 155 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 153007804 Common - Hydroxypyruvate isomerase Oant_0459 86 COG3622 Hfi, Hydroxypyruvate isomerase Carbohydrate transport and metabolism 153009817 Pathogen - conserved hypothetical membrane spanning protein Oant_2490 1 None None None 153009264 Common - transglutaminase family protein cysteine peptidase BTLCP Oant_1934 25 COG3672 COG3672, Predicted periplasmic protein Function unknown 153007714 Common - Glucose-6-phosphate isomerase Oant_0369 198 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 153008887 Pathogen - hypothetical protein Oant_1557 1 None None None 153008109 Common - protein of unknown function DUF454 Oant_0773 73 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 153008799 Common - NADH:flavin oxidoreductase/NADH oxidase Oant_1468 178 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 153009368 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Oant_2038 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 153007601 Common - Fibronectin type III domain protein Oant_0256 10 None None None 153007516 Common - sigma 54 modulation protein/ribosomal protein S30EA Oant_0171 61 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 153007410 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I Oant_0065 198 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 153008277 Common - tyrosine recombinase XerC Oant_0942 220 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 153009101 Pathogen - hypothetical protein Oant_1771 3 None None None 153007630 Common - phosphomethylpyrimidine kinase Oant_0285 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 153009544 Common - extracellular solute-binding protein family 3 Oant_2214 181 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153009358 Common - Domain of unknown function DUF1849 Oant_2028 19 None None None 153009888 Common - extracellular solute-binding protein family 3 Oant_2561 60 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153008532 Common - ribosomal protein L31 Oant_1201 113 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 153008741 Common - thiamine pyrophosphate protein domain protein TPP-binding Oant_1410 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 153009955 Common - signal peptidase I Oant_2628 206 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 153008371 Common - peptide chain release factor 1 Oant_1036 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 153007936 Common - ribonuclease H Oant_0591 181 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 153008080 Common - ribosomal protein S15 Oant_0744 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 153007623 Common - binding-protein-dependent transport systems inner membrane component Oant_0278 179 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 153009301 Common - ribosomal protein L6 Oant_1971 241 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 153009455 Common - HI0933 family protein Oant_2125 116 COG2081 COG2081, Predicted flavoproteins General function prediction only 153007780 Common - putative transcriptional regulator Oant_0435 51 COG2345 COG2345, Predicted transcriptional regulator Transcription 153009132 Common - diguanylate cyclase Oant_1802 179 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153009329 Common - protein of unknown function DUF1452 Oant_1999 26 COG5478 COG5478, Predicted small integral membrane protein Function unknown 153009664 Common - protein-export membrane protein SecD Oant_2336 218 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 153009697 Common - Aldose 1-epimerase Oant_2369 96 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 153009968 Common - dihydrodipicolinate synthase Oant_2641 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 153009871 Common - Polyphosphate kinase Oant_2544 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 153007920 Common - domain of unknown function DUF1732 Oant_0575 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 153008957 Common - MaoC domain protein dehydratase Oant_1627 55 COG2030 MaoC, Acyl dehydratase Lipid metabolism 153009581 Common - FeS assembly SUF system protein Oant_2251 148 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 153007873 Common - acyl-CoA dehydrogenase domain protein Oant_0528 145 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153008623 Common - ABC transporter related Oant_1292 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153009287 Common - ribosomal protein L4/L1e Oant_1957 218 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 153008208 Common - coenzyme A transferase Oant_0872 85 COG4670 COG4670, Acyl CoA:acetate/3-ketoacid CoA transferase Lipid metabolism 153007520 Common - hypothetical protein Oant_0175 20 COG5488 COG5488, Integral membrane protein Function unknown 153007359 Common - extracellular solute-binding protein family 5 Oant_0014 108 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 153007823 Common - arsenate reductase and related Oant_0478 108 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 153007593 Common - hypothetical protein Oant_0248 13 None None None 153008678 Common - Alcohol dehydrogenase zinc-binding domain protein Oant_1347 170 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 153008764 Common - urocanate hydratase Oant_1433 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 153008112 Common - RimK domain protein ATP-grasp Oant_0776 67 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 153007558 Common - hypothetical protein Oant_0213 9 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 153009677 Common - RNA-directed DNA polymerase (Reverse transcriptase) Oant_2349 94 COG3344 COG3344, Retron-type reverse transcriptase DNA replication, recombination, and repair 153008119 Common - glutathione synthetase Oant_0783 139 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 153009883 Common - polar amino acid ABC transporter, inner membrane subunit Oant_2556 172 COG4597 BatB, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 153009802 Common - extracellular solute-binding protein family 5 Oant_2475 204 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153009470 Common - Pyridoxal-5'-phosphate-dependent protein beta subunit Oant_2140 225 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 153008681 Common - succinyl-diaminopimelate desuccinylase Oant_1350 210 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 153007998 Common - transposase IS66 Oant_0659 58 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009763 Common - hypothetical protein Oant_2435 28 COG3247 HdeD, Uncharacterized conserved protein Function unknown 153007708 Common - binding-protein-dependent transport systems inner membrane component Oant_0363 159 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153009477 Common - Methyltransferase type 12 Oant_2147 32 COG4976 COG4976, Predicted methyltransferase (contains TPR repeat) General function prediction only 153007349 Common - DNA polymerase III, beta subunit Oant_0004 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 153009618 Common - hypothetical protein Oant_2288 2 None None None 153008222 Pathogen - hypothetical protein Oant_0886 1 None None None 153007405 Common - glucose-methanol-choline oxidoreductase Oant_0060 89 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 153008188 Common - maf protein Oant_0852 187 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 153008843 Pathogen - hypothetical protein Oant_1513 1 None None None 153008333 Pathogen - hypothetical protein Oant_0998 2 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 153009282 Common - ribosomal protein S7 Oant_1952 248 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 153009716 Common - putative transcriptional regulator, GntR family Oant_2388 182 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153008029 Common - cytochrome c class I Oant_0690 37 COG3258 COG3258, Cytochrome c Energy production and conversion 153009537 Common - GTP-binding protein HSR1-related Oant_2207 220 COG2262 HflX, GTPases General function prediction only 153009234 Common - binding-protein-dependent transport systems inner membrane component Oant_1904 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153008550 Pathogen - hypothetical protein Oant_1219 1 None None None 153007661 Common - MaoC domain protein dehydratase Oant_0316 92 COG2030 MaoC, Acyl dehydratase Lipid metabolism 153008413 Common - ribosomal protein S16 Oant_1079 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 153008834 Common - hypothetical protein Oant_1503 6 COG5471 COG5471, Uncharacterized conserved protein Function unknown 153007853 Common - Radical SAM domain protein Oant_0508 106 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 153008106 Common - phosphate ABC transporter, inner membrane subunit PstC Oant_0770 231 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 153009814 Common - LmbE family protein Oant_2487 23 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 153009245 Pathogen - hypothetical protein Oant_1915 2 None None None 153008453 Common - pyruvate carboxylase Oant_1119 238 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 153008851 Pathogen - hypothetical protein Oant_1521 1 None None None 153007583 Common - phage Terminase Oant_0238 39 COG4626 COG4626, Phage terminase-like protein, large subunit General function prediction only 153007468 Common - sulfate ABC transporter, ATPase subunit Oant_0123 249 COG1118 CysA, ABC-type sulfate/molybdate transport systems, ATPase component Inorganic ion transport and metabolism 153008574 Common - ferric uptake regulator, Fur family Oant_1243 187 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 153008154 Common - Double-strand break repair protein AddB Oant_0818 63 COG3893 COG3893, Inactivated superfamily I helicase DNA replication, recombination, and repair 153008737 Common - extracellular solute-binding protein family 3 Oant_1406 114 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153008052 Common - formamidopyrimidine-DNA glycosylase Oant_0716 178 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 153009414 Common - protein of unknown function DUF6 transmembrane Oant_2084 160 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 153009657 Common - phage integrase family protein Oant_2329 13 None None None 153008479 Common - ABC transporter related Oant_1145 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153008342 Common - ATP--cobalamin adenosyltransferase Oant_1007 129 COG2096 COG2096, Uncharacterized conserved protein Function unknown 153008310 Common - porphobilinogen deaminase Oant_0975 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 153008280 Common - hypothetical protein Oant_0945 13 None None None 153008458 Common - major facilitator superfamily MFS_1 Oant_1124 86 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153007679 Common - urease, beta subunit Oant_0334 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 153007959 Common - hypothetical protein Oant_0615 29 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 153008168 Common - pantothenate kinase Oant_0832 75 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 153008233 Common - transposase IS66 Oant_0898 63 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009590 Common - tyrosyl-tRNA synthetase Oant_2260 217 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153007499 Common - UspA domain protein Oant_0154 26 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 153007565 Common - hypothetical protein Oant_0220 2 COG4197 COG4197, Uncharacterized protein conserved in bacteria, prophage-related Function unknown 153009781 Common - Methyltransferase type 12 Oant_2453 15 COG4627 COG4627, Uncharacterized protein conserved in bacteria Function unknown 153009991 Common - integral membrane sensor signal transduction histidine kinase Oant_2665 220 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153008048 Common - transposase IS66 Oant_0711 63 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153008373 Common - hypothetical protein Oant_1038 32 COG5373 COG5373, Predicted membrane protein Function unknown 153008604 Common - disulfide bond formation protein B, putative Oant_1273 37 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 153008511 Common - Helix-turn-helix type 11 domain protein Oant_1180 102 COG2378 COG2378, Predicted transcriptional regulator Transcription 153007378 Common - Glutathione S-transferase domain protein Oant_0033 95 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153009278 Common - DNA-directed RNA polymerase, beta' subunit Oant_1948 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 153007527 Common - ribonuclease PH Oant_0182 182 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 153008467 Common - 4Fe-4S ferredoxin iron-sulfur binding domain protein Oant_1133 157 COG1146 COG1146, Ferredoxin Energy production and conversion 153007733 Common - O-antigen polymerase Oant_0388 15 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 153007449 Common - hypothetical protein Oant_0104 13 None None None 153008858 Pathogen - hypothetical protein Oant_1528 1 None None None 153008312 Common - hypothetical protein Oant_0977 25 COG4223 COG4223, Uncharacterized protein conserved in bacteria Function unknown 153007757 Common - 5-aminolevulinic acid synthase Oant_0412 190 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 153009194 Common - FAD dependent oxidoreductase Oant_1864 176 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 153008445 Common - proline racemase Oant_1111 47 COG3938 COG3938, Proline racemase Amino acid transport and metabolism 153009828 Common - 3''-kinase Oant_2501 25 COG3570 StrB, Streptomycin 6-kinase Defense mechanisms 153008611 Common - drug resistance transporter, EmrB/QacA subfamily Oant_1280 204 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153008812 Pathogen - hypothetical protein Oant_1481 1 None None None 153009583 Common - FeS assembly protein SufD Oant_2253 180 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 153009624 Common - phage major tail tube protein Oant_2294 29 COG3498 COG3498, Phage tail tube protein FII General function prediction only 153008977 Pathogen - hypothetical protein Oant_1647 2 None None None 153009640 Common - NusG antitermination factor Oant_2312 7 COG0250 NusG, Transcription antiterminator Transcription 153007815 Common - integral membrane sensor signal transduction histidine kinase Oant_0470 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153007419 Pathogen - hypothetical protein Oant_0074 2 None None None 153007895 Common - aspartate racemase Oant_0550 87 COG1794 RacX, Aspartate racemase Cell envelope biogenesis, outer membrane 153008025 Common - pyruvate, phosphate dikinase Oant_0686 233 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 153007701 Common - GntR domain protein Oant_0356 132 COG2186 FadR, Transcriptional regulators Transcription 153007438 Pathogen - hypothetical protein Oant_0093 2 None None None 153007542 Common - methionine synthase Oant_0197 174 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 153008527 Common - Integral membrane protein TerC Oant_1196 98 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 153009502 Common - luciferase family protein Oant_2172 113 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 153008294 Common - ammonium transporter Oant_0959 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 153009704 Common - Ribulose-phosphate 3-epimerase Oant_2376 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 153009505 Common - transcriptional regulator, TetR family Oant_2175 36 COG1309 AcrR, Transcriptional regulator Transcription 153010002 Pathogen - hypothetical protein Oant_2676 3 None None None 153009222 Common - Extracellular ligand-binding receptor Oant_1892 48 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 153008518 Common - Phosphoglycerate kinase Oant_1187 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 153009749 Common - glutathione-dependent formaldehyde-activating GFA Oant_2421 60 COG3791 COG3791, Uncharacterized conserved protein Function unknown 153008693 Common - ribonuclease P protein component Oant_1362 12 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 153009597 Common - N-acetylmuramoyl-L-alanine amidase Oant_2267 181 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 153009064 Common - short-chain dehydrogenase/reductase SDR Oant_1734 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153009698 Common - protein of unknown function DUF847 Oant_2370 31 COG3926 zliS, Putative secretion activating protein General function prediction only 153008958 Common - MaoC domain protein dehydratase Oant_1628 70 COG2030 MaoC, Acyl dehydratase Lipid metabolism 153008146 Common - tryptophan synthase, beta subunit Oant_0810 227 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 153009365 Common - putative membrane-associated zinc metalloprotease Oant_2035 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 153009638 Common - regulatory protein MerR Oant_2310 7 COG4220 COG4220, Phage DNA packaging protein, Nu1 subunit of terminase DNA replication, recombination, and repair 153008179 Common - transcriptional regulator, XRE family Oant_0843 12 COG1396 HipB, Predicted transcriptional regulators Transcription 153008344 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Oant_1009 111 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 153009142 Common - transcriptional regulator, TetR family Oant_1812 21 COG1309 AcrR, Transcriptional regulator Transcription 153008259 Common - intracellular septation protein A Oant_0924 92 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 153009662 Common - phytoene synthase Oant_2334 73 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 153008172 Common - imidazole glycerol phosphate synthase, glutamine amidotransferase subunit Oant_0836 214 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 153008170 Common - imidazoleglycerol phosphate synthase, cyclase subunit Oant_0834 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 153009079 Common - cell division protein FtsA Oant_1749 184 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 153008110 Pathogen - hypothetical protein Oant_0774 1 None None None 153009348 Pathogen - hypothetical protein Oant_2018 2 None None None 153009243 Common - hypothetical protein Oant_1913 18 COG3553 COG3553, Uncharacterized protein conserved in bacteria Function unknown 153009929 Common - permease YjgP/YjgQ family protein Oant_2602 57 COG0795 COG0795, Predicted permeases General function prediction only 153009203 Common - cobalt transporter, subunit CbtB Oant_1873 10 None None None 153007531 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Oant_0186 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 153010052 Common - hypothetical protein Oant_2727 5 None None None 153007954 Common - O-antigen polymerase Oant_0609 5 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 153007720 Common - efflux transporter, RND family, MFP subunit Oant_0375 136 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 153008946 Common - Coproporphyrinogen oxidase Oant_1616 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 153009033 Common - Penicillin amidase Oant_1703 55 COG3049 COG3049, Penicillin V acylase and related amidases Cell envelope biogenesis, outer membrane 153008367 Common - protein of unknown function DUF6 transmembrane Oant_1032 37 None None None 153007731 Common - polysaccharide biosynthesis protein Oant_0386 30 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 153008012 Common - hypothetical protein Oant_0673 10 None None None 153009340 Common - hypothetical protein Oant_2010 9 COG3851 UhpB, Signal transduction histidine kinase, glucose-6-phosphate specific Signal transduction mechanisms 153009794 Common - Transposase and inactivated derivatives-like protein Oant_2467 82 COG3293 COG3293, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009740 Common - proton-translocating NADH-quinone oxidoreductase, chain L Oant_2412 206 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 153008072 Common - GCN5-related N-acetyltransferase Oant_0736 56 COG0456 RimI, Acetyltransferases General function prediction only 153007721 Common - transporter, hydrophobe/amphiphile efflux-1 (HAE1) family Oant_0376 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 153008128 Common - protein of unknown function DUF925 Oant_0792 25 COG3575 COG3575, Uncharacterized protein conserved in bacteria Function unknown 153009574 Common - protein-L-isoaspartate(D-aspartate) O-methyltransferase Oant_2244 158 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 153007441 Common - 2'-5' RNA ligase Oant_0096 85 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 153007944 Common - threonine synthase Oant_0599 177 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 153009857 Common - Glycine hydroxymethyltransferase Oant_2530 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 153008503 Common - protein of unknown function DUF465 Oant_1171 18 COG5570 COG5570, Uncharacterized small protein Function unknown 153008938 Common - protein of unknown function DUF58 Oant_1608 70 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 153007511 Common - signal peptide peptidase SppA, 36K type Oant_0166 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153008060 Common - pilus (Caulobacter type) biogenesis lipoprotein CpaD Oant_0724 14 COG5461 COG5461, Type IV pili component Cell motility and secretion 153007431 Common - Argininosuccinate synthase Oant_0086 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 153008924 Common - major facilitator superfamily MFS_1 Oant_1594 108 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 153009511 Pathogen - hypothetical protein Oant_2181 1 None None None 153007550 Pathogen - hypothetical protein Oant_0205 1 None None None 153007972 Common - peptidase M55 D-aminopeptidase Oant_0629 35 COG2362 DppA, D-aminopeptidase Amino acid transport and metabolism 153007436 Common - hypothetical protein Oant_0091 31 None None None 153007742 Common - ApaG domain protein Oant_0397 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 153009027 Common - conserved hypothetical signal peptide protein Oant_1697 25 None None None 153007794 Common - Chitin deacetylase Oant_0449 65 COG3195 COG3195, Uncharacterized protein conserved in bacteria Function unknown 153008992 Common - putative transcriptional regulator, AsnC family Oant_1662 164 COG1522 Lrp, Transcriptional regulators Transcription 153007549 Pathogen - hypothetical protein Oant_0204 1 None None None 153007454 Common - Heme exporter protein D (CcmD) Oant_0109 5 None None None 153008807 Common - acyl-CoA dehydrogenase protein Oant_1476 113 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153008002 Common - hypothetical protein Oant_0663 2 None None None 153009560 Common - protein of unknown function DUF971 Oant_2230 49 COG3536 COG3536, Uncharacterized protein conserved in bacteria Function unknown 153007423 Common - Hly-III family protein Oant_0078 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 153008914 Common - binding-protein-dependent transport systems inner membrane component Oant_1584 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153009555 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit Oant_2225 146 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 153009519 Common - phosphonate metabolism protein PhnM Oant_2189 54 COG3454 COG3454, Metal-dependent hydrolase involved in phosphonate metabolism Inorganic ion transport and metabolism 153010037 Common - transposase IS3/IS911 family protein Oant_2711 117 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 153007668 Common - translation initiation factor IF-1 Oant_0323 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 153008995 Common - transcriptional regulator, LysR family Oant_1665 187 COG0583 LysR, Transcriptional regulator Transcription 153007909 Common - purine nucleoside permease Oant_0564 11 COG5042 NUP, Purine nucleoside permease Nucleotide transport and metabolism 153008785 Common - transcriptional regulator, GntR family Oant_1454 139 COG2188 PhnF, Transcriptional regulators Transcription 153009356 Common - glycerophosphoryl diester phosphodiesterase Oant_2026 129 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 153008380 Common - protein of unknown function DUF548 Oant_1046 48 None None None 153008177 Common - heat shock protein HslVU, ATPase subunit HslU Oant_0841 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 153008602 Common - HhH-GPD family protein Oant_1271 114 COG0122 AlkA, 3-methyladenine DNA glycosylase/8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 153008776 Common - alanine racemase Oant_1445 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 153009602 Common - 3-dehydroquinate dehydratase, type II Oant_2272 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 153009742 Common - NADH-ubiquinone/plastoquinone oxidoreductase chain 6 Oant_2414 70 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 153007361 Common - cytochrome c class I Oant_0016 56 COG3474 COG3474, Cytochrome c2 Energy production and conversion 153008890 Pathogen - hypothetical protein Oant_1560 1 None None None 153007907 Common - DNA repair protein RadA Oant_0562 218 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 153008254 Common - hypothetical protein Oant_0919 17 None None None 153007513 Common - OstA family protein Oant_0168 36 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 153008402 Common - methylmalonate-semialdehyde dehydrogenase Oant_1068 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153008046 Common - transposase IS3/IS911 family protein Oant_0709 19 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009291 Common - ribosomal protein L22 Oant_1961 216 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 153008198 Common - parB-like partition protein Oant_0862 182 COG1475 Spo0J, Predicted transcriptional regulators Transcription 153008214 Common - glutathione-dependent formaldehyde-activating GFA Oant_0878 53 COG3791 COG3791, Uncharacterized conserved protein Function unknown 153007850 Common - putative transcriptional regulator, AsnC family Oant_0505 159 COG1522 Lrp, Transcriptional regulators Transcription 153009546 Common - glycosyl transferase family 2 Oant_2216 128 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153008609 Common - aldo/keto reductase Oant_1278 183 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 153009253 Common - putative cold-shock DNA-binding domain protein Oant_1923 160 COG1278 CspC, Cold shock proteins Transcription 153009764 Common - MgtC/SapB transporter Oant_2436 119 COG1285 SapB, Uncharacterized membrane protein Function unknown 153010069 Common - yecA family protein Oant_2745 10 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 153007632 Common - heavy metal translocating P-type ATPase Oant_0287 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 153009052 Common - Methyltransferase type 11 Oant_1722 132 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153007693 Common - amidase, hydantoinase/carbamoylase family Oant_0348 84 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 153009332 Common - Carbamoyl-phosphate synthase L chain ATP-binding Oant_2002 240 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 153008094 Common - RNA modification enzyme, MiaB family Oant_0758 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 153008062 Common - type II secretion system protein E Oant_0726 161 COG4962 CpaF, Flp pilus assembly protein, ATPase CpaF Intracellular trafficking and secretion 153008388 Common - GTP-binding protein Obg/CgtA Oant_1054 249 COG0536 Obg, Predicted GTPase General function prediction only 153009333 Common - carboxyl transferase Oant_2003 216 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 153009435 Common - glycosyl transferase group 1 Oant_2105 177 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153008275 Pathogen - hypothetical protein Oant_0940 1 None None None 153007608 Pathogen - hypothetical protein Oant_0263 1 None None None 153008630 Pathogen - hypothetical protein Oant_1299 1 None None None 153007870 Common - FAD linked oxidase domain protein Oant_0525 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 153009605 Common - Leucyltransferase Oant_2275 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 153008037 Common - phage integrase family protein Oant_0699 29 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 153009451 Common - putative phosphohistidine phosphatase, SixA Oant_2121 75 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 153008469 Common - transcriptional regulator, LysR family Oant_1135 154 COG0583 LysR, Transcriptional regulator Transcription 153008121 Common - protein of unknown function DUF1330 Oant_0785 45 COG5470 COG5470, Uncharacterized conserved protein Function unknown 153008933 Common - OmpW family protein Oant_1603 72 COG3047 OmpW, Outer membrane protein W Cell envelope biogenesis, outer membrane 153008664 Common - methylglyoxal synthase Oant_1333 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 153009009 Common - carbamoyl-phosphate synthase, large subunit Oant_1679 232 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 153008990 Common - transcription elongation factor GreA Oant_1660 204 COG0782 GreA, Transcription elongation factor Transcription 153008240 Common - protein of unknown function DUF949 Oant_0905 48 COG3034 COG3034, Uncharacterized protein conserved in bacteria Function unknown 153007680 Common - urease, alpha subunit Oant_0335 97 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 153009183 Pathogen - hypothetical protein Oant_1853 2 None None None 153009469 Common - DEAD/DEAH box helicase domain protein Oant_2139 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 153009896 Common - ETC complex I subunit conserved region Oant_2569 36 None None None 153009923 Common - ABC transporter related Oant_2596 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153008657 Common - YhhN family protein Oant_1326 4 COG3714 COG3714, Predicted membrane protein Function unknown 153008488 Common - hypothetical protein Oant_1155 3 None None None 153009778 Common - amidohydrolase Oant_2450 82 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 153008403 Common - hypothetical protein Oant_1069 10 None None None 153008757 Common - Monosaccharide-transporting ATPase Oant_1426 117 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 153009954 Common - Ribonuclease III Oant_2627 216 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 153007534 Common - hypothetical protein Oant_0189 14 None None None 153009837 Common - hypothetical protein Oant_2510 12 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 153007911 Common - ribosomal protein L9 Oant_0566 216 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 153009108 Common - Phage DNA packaging protein Nu1 subunit of terminase-like protein Oant_1778 4 COG4220 COG4220, Phage DNA packaging protein, Nu1 subunit of terminase DNA replication, recombination, and repair 153009499 Common - L-carnitine dehydratase/bile acid-inducible protein F Oant_2169 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 153008283 Common - diguanylate cyclase Oant_0948 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153009151 Common - UspA domain protein Oant_1821 75 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 153008104 Common - phosphate ABC transporter, ATPase subunit Oant_0768 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 153008306 Common - protein of unknown function DUF55 Oant_0971 94 COG2947 COG2947, Uncharacterized conserved protein Function unknown 153008540 Common - conserved hypothetical OpgC protein Oant_1209 28 COG4645 COG4645, Uncharacterized protein conserved in bacteria Function unknown 153007651 Common - conserved hypothetical membrane-anchored protein Oant_0306 7 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153007941 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s) Oant_0596 181 COG2200 Rtn, FOG: EAL domain Signal transduction mechanisms 153009522 Common - phosphonate C-P lyase system protein PhnK Oant_2192 249 COG4107 PhnK, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 153008708 Common - D-isomer specific 2-hydroxyacid dehydrogenase NAD-binding Oant_1377 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 153009820 Common - CoA-binding domain protein Oant_2493 121 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 153007658 Common - Mandelate racemase/muconate lactonizing protein Oant_0313 133 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 153009913 Common - transcriptional regulator, LysR family Oant_2586 176 COG0583 LysR, Transcriptional regulator Transcription 153009946 Common - isochorismatase hydrolase Oant_2619 69 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 153008911 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Oant_1581 44 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 153009974 Common - phage integrase family protein Oant_2647 191 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153008591 Common - TadE family protein Oant_1260 11 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 153009808 Common - ABC transporter related Oant_2481 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153009169 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Oant_1839 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153008721 Common - hypothetical protein Oant_1390 15 None None None 153009087 Common - branched-chain amino acid transport Oant_1757 5 COG4541 COG4541, Predicted membrane protein Function unknown 153010020 Common - hypothetical protein Oant_2694 11 None None None 153008321 Common - protein of unknown function DUF218 Oant_0986 29 COG1434 COG1434, Uncharacterized conserved protein Function unknown 153009723 Pathogen - hypothetical protein Oant_2395 1 None None None 153009453 Common - hypothetical protein Oant_2123 13 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 153008369 Common - aspartate kinase Oant_1034 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 153007760 Common - glycosyl transferase family 25 Oant_0415 25 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 153008966 Common - creatinase Oant_1636 94 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 153007922 Pathogen - hypothetical protein Oant_0577 1 None None None 153009531 Common - dihydrodipicolinate synthase Oant_2201 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 153009160 Common - oxidoreductase domain protein Oant_1830 183 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153009576 Common - hypothetical protein Oant_2246 5 None None None 153007486 Common - S-formylglutathione hydrolase Oant_0141 95 COG0627 COG0627, Predicted esterase General function prediction only 153009266 Common - protein of unknown function DUF1457 Oant_1936 14 COG5388 COG5388, Uncharacterized protein conserved in bacteria Function unknown 153008790 Common - aldehyde dehydrogenase Oant_1459 221 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153010003 Common - penicillin-binding protein, 1A family Oant_2677 202 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 153009216 Common - precorrin-6x reductase Oant_1886 75 COG2099 CobK, Precorrin-6x reductase Coenzyme metabolism 153007879 Common - chaperone DnaJ domain protein Oant_0534 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 153009966 Common - Uracil-DNA glycosylase superfamily Oant_2639 58 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 153008824 Common - hypothetical protein Oant_1493 3 None None None 153009115 Common - hypothetical protein Oant_1785 17 COG4397 COG4397, Mu-like prophage major head subunit gpT General function prediction only 153007639 Common - Pyrrolo-quinoline quinone Oant_0294 61 COG4993 Gcd, Glucose dehydrogenase Carbohydrate transport and metabolism 153008335 Common - Redoxin domain protein Oant_1000 133 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 153008399 Common - Transglycosylase-associated protein Oant_1065 3 COG2261 COG2261, Predicted membrane protein Function unknown 153007884 Common - Chorismate synthase Oant_0539 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 153008082 Common - ribosome-binding factor A Oant_0746 86 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 153008319 Common - cell division ATP-binding protein FtsE Oant_0984 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 153009997 Common - cytochrome c-type biogenesis protein, putative Oant_2671 56 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 153009783 Common - amidohydrolase Oant_2455 172 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 153007961 Common - filamentation induced by cAMP protein Fic Oant_0617 104 COG3177 COG3177, Uncharacterized conserved protein Function unknown 153009900 Common - NAD-dependent epimerase/dehydratase Oant_2573 160 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153008359 Common - GCN5-related N-acetyltransferase Oant_1024 28 COG0456 RimI, Acetyltransferases General function prediction only 153008486 Common - hypothetical protein Oant_1153 13 None None None 153009016 Common - DNA primase Oant_1686 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 153009308 Common - ribosomal protein S13 Oant_1978 240 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 153007625 Common - NMT1/THI5 like domain protein Oant_0280 104 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 153008301 Common - conserved hypothetical cytosolic protein Oant_0966 38 COG3786 COG3786, Uncharacterized protein conserved in bacteria Function unknown 153008878 Common - TRAP-type uncharacterized transport system periplasmic component-like protein Oant_1548 4 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 153008114 Common - transglutaminase family protein cysteine peptidase BTLCP Oant_0778 26 COG3672 COG3672, Predicted periplasmic protein Function unknown 153009227 Common - precorrin-2 C20-methyltransferase Oant_1897 184 COG2243 CobF, Precorrin-2 methylase Coenzyme metabolism 153009930 Common - Organic solvent tolerance protein Oant_2603 120 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 153007399 Common - protein of unknown function DUF490 Oant_0054 70 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 153007762 Common - hypothetical protein Oant_0417 7 None None None 153007579 Pathogen - hypothetical protein Oant_0234 1 None None None 153007897 Common - hypothetical protein Oant_0552 11 COG3895 COG3895, Predicted periplasmic protein General function prediction only 153008885 Pathogen - hypothetical protein Oant_1555 1 None None None 153007711 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Oant_0366 228 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 153008296 Common - outer membrane lipoprotein carrier protein LolA Oant_0961 35 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 153009398 Common - CinA domain protein Oant_2068 189 COG1546 CinA, Uncharacterized protein (competence- and mitomycin-induced) General function prediction only 153007508 Common - conserved hypothetical protein 95 Oant_0163 103 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 153009412 Common - glucan exporter ATP-binding protein Oant_2082 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153009323 Common - hypothetical protein Oant_1993 29 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 153008906 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Oant_1576 218 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 153007890 Common - protein of unknown function DUF937 Oant_0545 25 COG3753 COG3753, Uncharacterized protein conserved in bacteria Function unknown 153008131 Common - major facilitator superfamily MFS_1 Oant_0795 132 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153008266 Common - succinyl-CoA synthetase, beta subunit Oant_0931 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 153008625 Common - Exonuclease RNase T and DNA polymerase III Oant_1294 66 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 153008429 Common - leucyl-tRNA synthetase Oant_1095 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153008557 Common - hypothetical protein Oant_1226 30 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 153009854 Common - riboflavin synthase, alpha subunit Oant_2527 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 153009289 Common - ribosomal protein L2 Oant_1959 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 153009462 Common - NUDIX hydrolase Oant_2132 31 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 153007910 Common - Cyclopropane-fatty-acyl-phospholipid synthase Oant_0565 138 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 153009869 Common - ribonuclease D Oant_2542 122 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 153010014 Common - Chromosomal replication initiator DnaA domain protein Oant_2688 14 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 153008215 Common - short-chain dehydrogenase/reductase SDR Oant_0879 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153007381 Common - acetoacetyl-CoA synthase Oant_0036 200 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 153008262 Common - Diaminopimelate epimerase Oant_0927 179 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 153009658 Common - hypothetical protein Oant_2330 18 COG4929 COG4929, Uncharacterized membrane-anchored protein Function unknown 153007390 Common - Stress responsive alpha-beta barrel domain protein Oant_0045 19 None None None 153008560 Common - D-3-phosphoglycerate dehydrogenase Oant_1229 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 153007844 Common - ATP sythase protein I, hypothetical Oant_0499 14 COG5336 COG5336, Uncharacterized protein conserved in bacteria Function unknown 153008220 Pathogen - hypothetical protein Oant_0884 2 COG3756 COG3756, Uncharacterized protein conserved in bacteria Function unknown 153009862 Common - Enoyl-CoA hydratase/isomerase Oant_2535 171 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 153008422 Common - Heparinase II/III family protein Oant_1088 45 COG5360 COG5360, Uncharacterized protein conserved in bacteria Function unknown 153008832 Common - hypothetical protein Oant_1501 3 None None None 153007572 Pathogen - Myb DNA-binding Oant_0227 1 None None None 153008637 Common - Resolvase domain protein Oant_1306 64 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 153008762 Common - protein of unknown function DUF886 Oant_1431 40 COG3758 COG3758, Uncharacterized protein conserved in bacteria Function unknown 153009683 Common - exodeoxyribonuclease III Xth Oant_2355 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 153009408 Common - DNA polymerase III, delta prime subunit domain protein Oant_2078 241 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 153008436 Common - ATP synthase F1, delta subunit Oant_1102 180 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 153008415 Common - LemA family protein Oant_1081 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 153007774 Common - quinolinate synthetase complex, A subunit Oant_0429 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 153008873 Common - helix-turn-helix domain protein Oant_1543 3 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 153007388 Common - protein tyrosine/serine phosphatase Oant_0043 18 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 153008098 Common - Ferritin Dps family protein Oant_0762 89 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 153009886 Common - cystathionine beta-lyase Oant_2559 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 153008227 Common - protein of unknown function DUF1130 Oant_0891 53 COG5483 COG5483, Uncharacterized conserved protein Function unknown 153007767 Common - LrgB family protein Oant_0422 84 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 153007860 Common - Na+/H+ antiporter NhaA Oant_0515 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 153008054 Common - TadE family protein Oant_0718 15 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 153009796 Common - Endoribonuclease L-PSP Oant_2469 103 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153008903 Common - hypothetical protein Oant_1573 64 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 153008108 Common - aminotransferase class I and II Oant_0772 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153008744 Common - OsmC family protein Oant_1413 7 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 153009868 Common - aspartyl-tRNA synthetase Oant_2541 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153009540 Common - two component, sigma54 specific, transcriptional regulator, Fis family Oant_2210 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 153008545 Common - thioesterase superfamily protein Oant_1214 125 COG0824 FcbC, Predicted thioesterase General function prediction only 153009405 Common - rare lipoprotein A Oant_2075 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 153009403 Common - hypothetical protein Oant_2073 2 None None None 153008882 Common - Exonuclease RNase T and DNA polymerase III Oant_1552 9 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 153008876 Pathogen - hypothetical protein Oant_1546 1 None None None 153008030 Common - hypothetical protein Oant_0691 30 None None None 153007589 Common - hypothetical protein Oant_0244 5 None None None 153009750 Common - NADH (or F420H2) dehydrogenase, subunit C Oant_2422 177 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 153009993 Common - protease Do Oant_2667 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 153008166 Common - Class I peptide chain release factor Oant_0830 108 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 153010075 Common - hypothetical protein Oant_2751 14 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 153008515 Pathogen - hypothetical protein Oant_1184 2 None None None 153009722 Common - PP-loop domain protein Oant_2394 142 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 153009426 Common - diacylglycerol kinase Oant_2096 77 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 153007862 Common - methyltransferase small Oant_0517 29 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 153008485 Common - hypothetical protein Oant_1152 11 None None None 153008562 Common - Adenylosuccinate synthase Oant_1231 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 153007923 Common - hypothetical protein Oant_0578 45 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009712 Common - phosphoribosylformylglycinamidine synthase I Oant_2384 231 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 153007616 Common - aldehyde dehydrogenase Oant_0271 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153009421 Common - phosphoglycolate phosphatase Oant_2091 188 COG0546 Gph, Predicted phosphatases General function prediction only 153008985 Common - thioesterase superfamily protein Oant_1655 135 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 153008268 Common - 2-oxoglutarate dehydrogenase, E1 subunit Oant_0933 148 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 153008434 Common - primosomal protein N' Oant_1100 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 153007912 Common - hypothetical protein Oant_0567 11 None None None 153007901 Common - phosphatidylserine decarboxylase related protein Oant_0556 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 153008226 Common - hypothetical protein Oant_0890 16 None None None 153009359 Common - ribosomal protein S2 Oant_2029 223 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 153008769 Common - transcriptional regulator, GntR family Oant_1438 120 COG2188 PhnF, Transcriptional regulators Transcription 153008641 Common - hypothetical protein Oant_1310 12 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 153009493 Common - hypothetical protein Oant_2163 2 None None None 153008352 Common - Cystathionine gamma-synthase Oant_1017 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 153008276 Common - GumN family protein Oant_0941 49 COG3735 COG3735, Uncharacterized protein conserved in bacteria Function unknown 153008554 Common - ATP-dependent metalloprotease FtsH Oant_1223 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 153009305 Common - ribosomal protein L15 Oant_1975 210 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 153009459 Common - MscS Mechanosensitive ion channel Oant_2129 64 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 153009533 Common - histone family protein DNA-binding protein Oant_2203 213 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 153010044 Common - dTDP-glucose 4,6-dehydratase Oant_2719 229 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 153009973 Common - porin Oant_2646 13 None None None 153009022 Common - hypothetical protein Oant_1692 5 None None None 153009521 Common - phosphonate C-P lyase system protein PhnL Oant_2191 249 COG4778 PhnL, ABC-type phosphonate transport system, ATPase component Inorganic ion transport and metabolism 153009692 Common - TIM-barrel protein, yjbN family Oant_2364 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 153007994 Common - GHMP kinase Oant_0654 20 COG4542 PduX, Protein involved in propanediol utilization, and related proteins (includes coumermycin biosynthetic protein), possible kinase Secondary metabolites biosynthesis, transport, and catabolism 153007395 Common - Cytochrome o ubiquinol oxidase subunit III Oant_0050 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 153009276 Common - ribosomal protein L7/L12 Oant_1946 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 153007952 Common - A/G-specific adenine glycosylase Oant_0607 220 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 153009964 Common - DNA-directed RNA polymerase, omega subunit Oant_2637 115 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 153009959 Common - major facilitator superfamily MFS_1 Oant_2632 121 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153009919 Common - molybdopterin biosynthesis MoaE protein Oant_2592 153 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 153007665 Common - protein of unknown function DUF606 Oant_0320 56 COG3238 COG3238, Uncharacterized protein conserved in bacteria Function unknown 153008095 Common - phospholipid/glycerol acyltransferase Oant_0759 104 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 153007626 Common - Thiamine-phosphate diphosphorylase Oant_0281 200 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 153007887 Common - exodeoxyribonuclease VII, small subunit Oant_0542 124 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 153008871 Pathogen - hypothetical protein Oant_1541 1 None None None 153009528 Common - arsenate reductase Oant_2198 110 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 153009958 Common - transcriptional regulator, AraC family Oant_2631 83 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153007783 Common - Saccharopine dehydrogenase Oant_0438 52 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 153007809 Common - FixH family protein Oant_0464 24 COG5456 COG5456, Predicted integral membrane protein linked to a cation pump Inorganic ion transport and metabolism 153008115 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_0779 41 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 153008253 Common - ribosomal protein L28 Oant_0918 150 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 153007677 Common - urease, gamma subunit Oant_0332 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 153009312 Common - protease Do Oant_1982 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 153008063 Common - type II secretion system protein Oant_0727 79 COG4965 TadB, Flp pilus assembly protein TadB Intracellular trafficking and secretion 153007491 Common - GCN5-related N-acetyltransferase Oant_0146 65 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 153008085 Common - NusA antitermination factor Oant_0749 219 COG0195 NusA, Transcription elongation factor Transcription 153007881 Common - Phosphoglycerate mutase Oant_0536 126 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 153008795 Common - binding-protein-dependent transport systems inner membrane component Oant_1464 191 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 153007577 Pathogen - hypothetical protein Oant_0232 1 None None None 153009030 Common - hypothetical protein Oant_1700 5 None None None 153009201 Common - acyl-CoA dehydrogenase domain protein Oant_1871 163 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153009876 Common - transcriptional regulator, HxlR family Oant_2549 123 COG1733 COG1733, Predicted transcriptional regulators Transcription 153009325 Common - RNA methyltransferase, TrmH family, group 1 Oant_1995 156 COG0565 LasT, rRNA methylase Translation, ribosomal structure and biogenesis 153008822 Common - hypothetical protein Oant_1491 26 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 153009363 Common - undecaprenyl diphosphate synthase Oant_2033 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 153007604 Common - glycosyl transferase family 2 Oant_0259 62 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 153007376 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Oant_0031 232 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 153009614 Pathogen - hypothetical protein Oant_2284 1 None None None 153009337 Common - GTP cyclohydrolase I Oant_2007 134 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 153009468 Common - threonine dehydratase Oant_2138 216 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 153008464 Common - acetyl-CoA acetyltransferase Oant_1130 170 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 153007682 Common - urease accessory protein UreF, putative Oant_0337 65 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 153008384 Common - ribosomal protein L21 Oant_1050 214 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 153007654 Common - extracellular solute-binding protein family 1 Oant_0309 89 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153009898 Pathogen - hypothetical protein Oant_2571 2 None None None 153008742 Common - protein of unknown function DUF72 Oant_1411 86 COG1801 COG1801, Uncharacterized conserved protein Function unknown 153009825 Common - hypothetical protein Oant_2498 35 COG2329 COG2329, Uncharacterized enzyme involved in biosynthesis of extracellular polysaccharides General function prediction only 153007567 Pathogen - hypothetical protein Oant_0222 1 None None None 153008247 Common - BolA family protein Oant_0912 68 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 153009185 Common - sulfate ABC transporter, inner membrane subunit CysT Oant_1855 236 COG0555 CysU, ABC-type sulfate transport system, permease component Posttranslational modification, protein turnover, chaperones 153007389 Pathogen - hypothetical protein Oant_0044 2 None None None 153007610 Common - protein of unknown function DUF1062 Oant_0265 10 COG4332 COG4332, Uncharacterized protein conserved in bacteria Function unknown 153009952 Common - DNA repair protein RecO Oant_2625 39 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 153008325 Common - ChaC family protein Oant_0990 44 COG3703 ChaC, Uncharacterized protein involved in cation transport Inorganic ion transport and metabolism 153007768 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_0423 38 COG0400 COG0400, Predicted esterase General function prediction only 153009938 Common - cysteinyl-tRNA synthetase Oant_2611 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153008123 Common - NADPH-dependent FMN reductase Oant_0787 115 COG0431 COG0431, Predicted flavoprotein General function prediction only 153007802 Common - Transcriptional regulator IclR Oant_0457 122 COG1414 IclR, Transcriptional regulator Transcription 153007463 Common - hypothetical protein Oant_0118 3 None None None 153007363 Common - Prephenate dehydratase Oant_0018 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 153009655 Common - hypothetical protein Oant_2327 12 None None None 153009430 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) (NADP(+)), Phosphate acetyltransferase Oant_2100 209 COG0281 SfcA, Malic enzyme Energy production and conversion 153008597 Common - Rubrerythrin Oant_1266 27 COG1633 COG1633, Uncharacterized conserved protein Function unknown 153009834 Common - glycosyl transferase group 1 Oant_2507 163 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153008789 Common - formyltetrahydrofolate deformylase Oant_1458 217 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 153008916 Common - ABC transporter related Oant_1586 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 153009093 Common - CreA family protein Oant_1763 56 COG3045 CreA, Uncharacterized protein conserved in bacteria Function unknown 153008375 Common - ErfK/YbiS/YcfS/YnhG family protein Oant_1040 87 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153009895 Common - transcriptional regulator, LysR family Oant_2568 171 COG0583 LysR, Transcriptional regulator Transcription 153008750 Common - protein of unknown function DUF1238 Oant_1419 14 COG3802 GguC, Uncharacterized protein conserved in bacteria Function unknown 153008813 Common - hypothetical protein Oant_1482 6 None None None 153009255 Common - alpha/beta hydrolase fold Oant_1925 128 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153009003 Common - transcriptional regulator, TetR family Oant_1673 55 COG1309 AcrR, Transcriptional regulator Transcription 153007400 Common - ErfK/YbiS/YcfS/YnhG family protein Oant_0055 73 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153008593 Common - deoxyuridine 5'-triphosphate nucleotidohydrolase Dut Oant_1262 183 COG0756 Dut, dUTPase Nucleotide transport and metabolism 153008626 Common - FAD dependent oxidoreductase Oant_1295 106 COG0579 COG0579, Predicted dehydrogenase General function prediction only 153008289 Common - succinate dehydrogenase and fumarate reductase iron-sulfur protein Oant_0954 193 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 153009267 Common - Rhomboid family protein Oant_1937 58 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 153008232 Common - hypothetical protein Oant_0896 5 None None None 153008398 Common - NUDIX hydrolase Oant_1064 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 153009165 Common - hypothetical protein Oant_1835 6 None None None 153007982 Common - ABC transporter related Oant_0640 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153009782 Common - Methyltransferase type 11 Oant_2454 17 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153010024 Common - hypothetical protein Oant_2698 13 None None None 153008652 Common - peptide chain release factor 3 Oant_1321 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 153008216 Pathogen - hypothetical protein Oant_0880 1 None None None 153008408 Common - Carbonate dehydratase Oant_1074 151 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 153009675 Common - chromosome segregation and condensation protein ScpA Oant_2347 121 COG1354 COG1354, Uncharacterized conserved protein Function unknown 153008391 Common - nicotinate (nicotinamide) nucleotide adenylyltransferase Oant_1057 169 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 153010009 Common - integral membrane sensor signal transduction histidine kinase Oant_2683 215 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153007467 Common - sulfate ABC transporter, inner membrane subunit CysW Oant_0122 198 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 153009436 Common - Mandelate racemase/muconate lactonizing protein Oant_2106 120 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 153009134 Common - acetolactate synthase, large subunit, biosynthetic type Oant_1804 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 153009050 Common - metabolite/H+ symporter, major facilitator superfamily (MFS) Oant_1720 141 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153009775 Common - hypothetical protein Oant_2447 2 None None None 153008771 Common - hypothetical protein Oant_1440 25 COG3652 COG3652, Predicted outer membrane protein Function unknown 153008715 Common - alanine dehydrogenase/PNT domain protein Oant_1384 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 153009986 Common - major facilitator superfamily MFS_1 Oant_2660 70 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153010028 Common - major facilitator superfamily MFS_1 Oant_2702 77 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 153009759 Common - proteinase inhibitor I11 ecotin Oant_2431 23 COG4574 Eco, Serine protease inhibitor ecotin General function prediction only 153007715 Common - Succinylglutamate desuccinylase/aspartoacylase Oant_0370 28 COG3608 COG3608, Predicted deacylase General function prediction only 153009443 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Oant_2113 64 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 153009045 Common - lipid A biosynthesis domain protein Oant_1715 23 COG3952 COG3952, Predicted membrane protein Function unknown 153010054 Common - IS66 Orf2 family protein Oant_2729 45 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009881 Common - ABC transporter related Oant_2554 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 153008201 Common - ABC transporter related Oant_0865 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 153008894 Common - oxidoreductase domain protein Oant_1564 184 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153009450 Common - protein of unknown function DUF463 YcjX family protein Oant_2120 42 COG3106 COG3106, Predicted ATPase General function prediction only 153008193 Common - protein of unknown function DUF255 Oant_0857 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 153009569 Common - 6-phosphogluconate dehydrogenase NAD-binding Oant_2239 189 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 153009128 Common - HI0933 family protein Oant_1798 136 COG2081 COG2081, Predicted flavoproteins General function prediction only 153009941 Common - NUDIX hydrolase Oant_2614 133 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 153007560 Pathogen - hypothetical protein Oant_0215 1 None None None 153009258 Pathogen - hypothetical protein Oant_1928 1 None None None 153007434 Common - hypothetical protein Oant_0089 3 None None None 153008865 Common - hypothetical protein Oant_1535 26 COG3598 RepA, RecA-family ATPase DNA replication, recombination, and repair 153007533 Common - uroporphyrin-III C-methyltransferase Oant_0188 204 COG0007 CysG, Uroporphyrinogen-III methylase Coenzyme metabolism 153008988 Common - protein of unknown function DUF6 transmembrane Oant_1658 89 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 153009557 Common - transcriptional regulator, TetR family Oant_2227 80 COG1309 AcrR, Transcriptional regulator Transcription 153008961 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Oant_1631 191 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 153007536 Common - phosphoadenosine phosphosulfate reductase Oant_0191 151 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 153008913 Common - Alkaline phosphatase Oant_1583 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153009512 Common - DNA gyrase, A subunit Oant_2182 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 153007590 Common - uncharacterized phage protein Oant_0245 6 None None None 153009065 Common - Mn2+/Fe2+ transporter, NRAMP family Oant_1735 114 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 153007718 Common - AMP-dependent synthetase and ligase Oant_0373 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153008525 Common - 5-formyltetrahydrofolate cyclo-ligase Oant_1194 177 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 153008568 Common - pseudouridine synthase, RluA family Oant_1237 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 153009925 Common - hypothetical protein Oant_2598 3 None None None 153009852 Common - NusB antitermination factor Oant_2525 172 COG0781 NusB, Transcription termination factor Transcription 153009387 Common - protein of unknown function DUF1428 Oant_2057 39 COG5507 COG5507, Uncharacterized conserved protein Function unknown 153009354 Common - histidine triad (HIT) protein Oant_2024 223 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 153008013 Common - virB1 type IV secretion protein Oant_0674 24 None None None 153010000 Common - two component transcriptional regulator, winged helix family Oant_2674 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153007899 Common - regulatory protein ArsR Oant_0554 64 COG0640 ArsR, Predicted transcriptional regulators Transcription 153008731 Common - ABC transporter related Oant_1400 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153008635 Common - hypothetical protein Oant_1304 13 None None None 153009173 Common - conserved hypothetical acid-shock protein Oant_1843 11 None None None 153007766 Common - LrgA family protein Oant_0421 20 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 153007450 Common - aconitate hydratase 1 Oant_0105 223 COG1048 AcnA, Aconitase A Energy production and conversion 153008205 Common - protein of unknown function DUF993 Oant_0869 21 None None None 153008056 Common - Flp/Fap pilin component Oant_0720 5 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 153009369 Common - acyl-(acyl-carrier-protein)--UDP-N-acetylglucosamine O-acyltransferase Oant_2039 142 COG1043 LpxA, Acyl- acyl carrier protein 153007732 Common - lipopolysaccharide biosynthesis protein Oant_0387 33 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 153009736 Common - beta-lactamase domain protein Oant_2408 157 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 153008323 Common - Inorganic diphosphatase Oant_0988 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 153007937 Common - Redoxin domain protein Oant_0592 81 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 153008005 Common - peptidase M24 Oant_0666 234 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 153007989 Common - Ti-type conjugative transfer system TraG Oant_0647 63 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 153008430 Common - hypothetical protein Oant_1096 7 COG5468 COG5468, Predicted secreted (periplasmic) protein Function unknown 153007483 Common - DEAD/DEAH box helicase domain protein Oant_0138 243 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 153009374 Common - ComEC/Rec2-related protein Oant_2044 133 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 153008347 Common - Electron transfer flavoprotein alpha subunit Oant_1012 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 153007557 Common - hypothetical protein Oant_0212 4 None None None 153008800 Common - putative transcriptional regulator, AsnC family Oant_1469 138 COG1522 Lrp, Transcriptional regulators Transcription 153008923 Common - protein of unknown function DUF6 transmembrane Oant_1593 21 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 153008793 Common - FAD dependent oxidoreductase Oant_1462 118 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153008221 Pathogen - hypothetical protein Oant_0885 1 None None None 153008918 Common - binding-protein-dependent transport systems inner membrane component Oant_1588 209 COG4176 ProW, ABC-type proline/glycine betaine transport system, permease component Amino acid transport and metabolism 153009345 Pathogen - hypothetical protein Oant_2015 2 None None None 153009589 Common - small multidrug resistance protein Oant_2259 145 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 153009260 Common - transcriptional regulator, TetR family Oant_1930 27 COG1309 AcrR, Transcriptional regulator Transcription 153008672 Common - GTP-binding protein LepA Oant_1341 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 153009091 Common - hypothetical protein Oant_1761 20 None None None 153007978 Common - transposase IS4 family protein Oant_0636 17 None None None 153007700 Common - Cystathionine gamma-synthase Oant_0355 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 153007734 Common - Transposase and inactivated derivatives-like protein Oant_0389 47 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 153008504 Common - major facilitator superfamily MFS_1 Oant_1172 60 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153007442 Common - lipolytic protein G-D-S-L family Oant_0097 109 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 153007707 Common - binding-protein-dependent transport systems inner membrane component Oant_0362 167 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153009703 Common - lipid A biosynthesis acyltransferase Oant_2375 107 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 153007960 Common - hypothetical protein Oant_0616 8 COG2929 COG2929, Uncharacterized protein conserved in bacteria Function unknown 153009798 Common - binding-protein-dependent transport systems inner membrane component Oant_2471 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153008942 Common - Polynucleotide adenylyltransferase region Oant_1612 170 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 153010036 Common - betaine aldehyde dehydrogenase Oant_2710 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153009747 Common - NADH-quinone oxidoreductase, E subunit Oant_2419 155 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 153008174 Common - Imidazoleglycerol-phosphate dehydratase Oant_0838 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 153009149 Common - phenazine biosynthesis protein PhzF family Oant_1819 107 COG0384 COG0384, Predicted epimerase, PhzC/PhzF homolog General function prediction only 153007465 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Oant_0120 90 COG1613 Sbp, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 153007865 Common - Tetratricopeptide TPR_2 repeat protein Oant_0520 169 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 153008297 Common - exodeoxyribonuclease III Xth Oant_0962 193 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 153008618 Common - short-chain dehydrogenase/reductase SDR Oant_1287 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153010011 Common - Fe-S metabolism associated SufE Oant_2685 100 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 153008368 Common - ubiquinone biosynthesis O-methyltransferase Oant_1033 110 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 153009153 Common - secretion protein HlyD family protein Oant_1823 99 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 153008852 Pathogen - hypothetical protein Oant_1522 1 None None None 153007817 Common - cytochrome c biogenesis protein transmembrane region Oant_0472 111 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 153009506 Common - queuine tRNA-ribosyltransferase Oant_2176 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 153007415 Common - Monosaccharide-transporting ATPase Oant_0070 176 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153010059 Common - transposase IS3/IS911 family protein Oant_2735 117 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009313 Common - AAA ATPase central domain protein Oant_1983 235 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 153009509 Common - peptidyl-prolyl cis-trans isomerase cyclophilin type Oant_2179 199 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 153009595 Common - peptide chain release factor 2 Oant_2265 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 153008937 Common - hypothetical protein Oant_1607 31 None None None 153009648 Common - hypothetical protein Oant_2320 2 None None None 153008787 Common - N-acetylglucosamine-6-phosphate deacetylase Oant_1456 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 153008144 Common - protein of unknown function DUF218 Oant_0808 11 COG1434 COG1434, Uncharacterized conserved protein Function unknown 153008360 Common - mutator MutT protein Oant_1025 173 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 153008696 Common - Endoribonuclease L-PSP Oant_1365 135 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153008949 Common - purine nucleoside permease Oant_1619 11 COG5042 NUP, Purine nucleoside permease Nucleotide transport and metabolism 153009070 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Oant_1740 209 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 153009362 Common - ribosome recycling factor Oant_2032 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 153007413 Common - ROK family protein Oant_0068 73 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 153010047 Common - glycosyl transferase family 2 Oant_2722 96 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 153007793 Common - protein of unknown function DUF861 cupin_3 Oant_0448 33 COG3257 GlxB, Uncharacterized protein, possibly involved in glyoxylate utilization General function prediction only 153007756 Common - aminotransferase class I and II Oant_0411 234 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153007548 Common - phage integrase family protein Oant_0203 17 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153008477 Common - thiamine pyrophosphokinase Oant_1143 40 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 153007403 Common - protein of unknown function DUF461 Oant_0058 87 COG4549 COG4549, Uncharacterized protein conserved in bacteria Function unknown 153009193 Common - hypothetical protein Oant_1863 6 None None None 153008571 Pathogen - hypothetical protein Oant_1240 1 None None None 153009208 Common - cob(I)alamin adenosyltransferase Oant_1878 142 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 153009971 Common - hypothetical protein Oant_2644 13 None None None 153009637 Common - phage terminase GpA Oant_2309 37 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 153008582 Common - hypothetical protein Oant_1251 14 None None None 153008412 Common - chorismate mutase Oant_1078 53 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 153007810 Common - Cytochrome c oxidase cbb3 type accessory protein FixG Oant_0465 77 COG0348 NapH, Polyferredoxin Energy production and conversion 153008854 Pathogen - hypothetical protein Oant_1524 1 None None None 153009806 Common - hypothetical protein Oant_2479 4 None None None 153009014 Common - GatB/Yqey domain protein Oant_1684 151 COG1610 COG1610, Uncharacterized conserved protein Function unknown 153008350 Common - cysteine synthase A Oant_1015 219 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 153009711 Common - phosphoribosylformylglycinamidine synthase, purS Oant_2383 116 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 153008182 Common - import inner membrane translocase subunit Tim44 Oant_0846 44 COG4395 COG4395, Uncharacterized protein conserved in bacteria Function unknown 153008747 Common - Monosaccharide-transporting ATPase Oant_1416 119 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153007830 Common - SbmABacA family protein Oant_0485 59 COG1133 SbmA, ABC-type long-chain fatty acid transport system, fused permease and ATPase components Lipid metabolism 153007545 Common - sulfate adenylyltransferase, small subunit Oant_0200 134 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 153007582 Common - hypothetical protein Oant_0237 4 None None None 153009623 Pathogen - hypothetical protein Oant_2293 2 None None None 153009912 Common - beta-lactamase Oant_2585 99 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 153008238 Common - cobalamin synthesis protein P47K Oant_0903 126 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 153009907 Common - protein of unknown function DUF6 transmembrane Oant_2580 51 COG2510 COG2510, Predicted membrane protein Function unknown 153008151 Common - hypothetical protein Oant_0815 45 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009413 Common - pseudouridine synthase, RluA family Oant_2083 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 153007352 Common - GCN5-related N-acetyltransferase Oant_0007 19 COG0456 RimI, Acetyltransferases General function prediction only 153008844 Pathogen - hypothetical protein Oant_1514 1 None None None 153007840 Common - transcriptional activator, TenA family Oant_0495 36 COG0819 TenA, Putative transcription activator Transcription 153008830 Common - GPW/gp25 family protein Oant_1499 23 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 153007570 Common - acyl carrier protein Oant_0225 200 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153008666 Common - drug resistance transporter, Bcr/CflA subfamily Oant_1335 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153009902 Common - protein of unknown function UPF0118 Oant_2575 146 COG0628 PerM, Predicted permease General function prediction only 153009321 Common - Glutathione S-transferase domain protein Oant_1991 93 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153007855 Pathogen - hypothetical protein Oant_0510 2 None None None 153007470 Common - nicotinate phosphoribosyltransferase Oant_0125 62 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 153008431 Common - beta-lactamase domain protein Oant_1097 29 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 153008537 Common - translation elongation factor P Oant_1206 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 153007653 Common - regulatory protein IclR Oant_0308 101 COG1414 IclR, Transcriptional regulator Transcription 153007839 Common - hypothetical protein Oant_0494 3 None None None 153008045 Common - IstB domain protein ATP-binding protein Oant_0708 101 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 153009210 Common - protein of unknown function DUF81 Oant_1880 137 COG0730 COG0730, Predicted permeases General function prediction only 153007367 Common - conserved hypothetical protein 103 Oant_0022 126 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 153007347 Common - ribosomal protein S20 Oant_0002 183 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 153008608 Common - transcriptional regulator, LysR family Oant_1277 170 COG0583 LysR, Transcriptional regulator Transcription 153009038 Common - hypothetical protein Oant_1708 19 COG5472 COG5472, Predicted small integral membrane protein Function unknown 153008454 Common - transcriptional regulator, DeoR family Oant_1120 115 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 153007875 Common - 4-hydroxybenzoate polyprenyl transferase Oant_0530 166 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 153009748 Common - NADH dehydrogenase I, D subunit Oant_2420 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 153008928 Common - cation diffusion facilitator family transporter Oant_1598 213 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 153007996 Common - transposase IS3/IS911 family protein Oant_0657 117 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 153008684 Pathogen - hypothetical protein Oant_1353 2 None None None 153008137 Common - ribosomal protein L35 Oant_0801 43 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 153009246 Common - aminotransferase class I and II Oant_1916 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 153009448 Common - hypothetical protein Oant_2118 6 None None None 153008968 Common - protein of unknown function DUF185 Oant_1638 94 COG1565 COG1565, Uncharacterized conserved protein Function unknown 153007606 Common - hypothetical protein Oant_0261 12 COG3179 COG3179, Predicted chitinase General function prediction only 153008704 Common - cobalamin synthesis protein P47K Oant_1373 128 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 153008009 Common - regulatory protein LuxR Oant_0670 37 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 153008196 Common - methyltransferase GidB Oant_0860 173 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 153009186 Common - sulfate ABC transporter, inner membrane subunit CysW Oant_1856 217 COG4208 CysW, ABC-type sulfate transport system, permease component Inorganic ion transport and metabolism 153008529 Common - BioY protein Oant_1198 81 COG1268 BioY, Uncharacterized conserved protein General function prediction only 153007728 Common - glycosyl transferase family 2 Oant_0383 109 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153007455 Common - periplasmic protein thiol--disulphide oxidoreductase DsbE Oant_0110 156 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 153008662 Common - ABC transporter related Oant_1331 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153007506 Common - lipoprotein signal peptidase Oant_0161 199 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 153007695 Common - NUDIX hydrolase Oant_0350 13 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 153008317 Pathogen - hypothetical protein Oant_0982 2 None None None 153008978 Common - beta-lactamase domain protein Oant_1648 219 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 153008578 Common - hypothetical protein Oant_1247 5 None None None 153009573 Common - type I secretion outer membrane protein, TolC family Oant_2243 147 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 153008491 Pathogen - hypothetical protein Oant_1159 4 None None None 153008496 Common - protein of unknown function DUF1036 Oant_1164 18 COG5480 COG5480, Predicted integral membrane protein Function unknown 153008498 Common - Tetratricopeptide TPR_2 repeat protein Oant_1166 47 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 153009686 Common - hypothetical protein Oant_2358 56 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 153009776 Pathogen - 17 kDa surface antigen Oant_2448 2 None None None 153008767 Common - imidazolonepropionase Oant_1436 104 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 153008601 Common - glutamyl-tRNA synthetase class Ic Oant_1270 245 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 153009720 Common - drug resistance transporter, Bcr/CflA subfamily Oant_2392 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153009233 Common - ABC transporter related Oant_1903 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153008331 Common - hypothetical protein Oant_0996 28 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 153009765 Common - Citrate transporter Oant_2437 44 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 153007528 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_0183 29 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 153009663 Common - protein of unknown function DUF498 Oant_2335 40 COG3737 COG3737, Uncharacterized conserved protein Function unknown 153009269 Common - RNA methyltransferase, TrmH family, group 3 Oant_1939 213 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 153008552 Common - Tol-Pal system YbgF Oant_1221 93 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 153008955 Common - cytochrome c1 Oant_1625 68 COG2857 CYT1, Cytochrome c1 Energy production and conversion 153007883 Common - protein of unknown function DUF1344 Oant_0538 6 None None None 153010046 Common - glucose-1-phosphate thymidylyltransferase Oant_2721 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 153009131 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Oant_1801 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 153009729 Common - NAD-dependent epimerase/dehydratase Oant_2401 110 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 153007575 Common - DNA (cytosine-5-)-methyltransferase Oant_0230 80 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 153009632 Common - phage-related baseplate assembly protein V Oant_2302 23 COG4540 gpV, Phage P2 baseplate assembly protein gpV General function prediction only 153009962 Common - orotate phosphoribosyltransferase Oant_2635 108 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 153007675 Common - cytochrome c oxidase subunit I Oant_0330 37 COG5473 COG5473, Predicted integral membrane protein Function unknown 153009784 Common - extracellular solute-binding protein family 3 Oant_2456 176 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153008643 Common - peptide methionine sulfoxide reductase Oant_1312 204 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 153010068 Common - transposase IS66 Oant_2744 60 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153008889 Pathogen - hypothetical protein Oant_1559 1 None None None 153007992 Common - Ti-type conjugative transfer relaxase TraA Oant_0650 89 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 153008097 Common - peptidase M22 glycoprotease Oant_0761 196 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 153009457 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Oant_2127 111 COG2072 TrkA, Predicted flavoprotein involved in K+ transport Inorganic ion transport and metabolism 153009495 Common - hypothetical protein Oant_2165 7 None None None 153009303 Common - ribosomal protein S5 Oant_1973 247 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 153009438 Common - ABC transporter related Oant_2108 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 153009613 Pathogen - hypothetical protein Oant_2283 1 None None None 153009352 Common - AzlC family protein Oant_2022 10 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 153007958 Common - chromosome segregation protein SMC Oant_0613 175 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 153008135 Common - hypothetical protein Oant_0799 17 None None None 153009111 Common - hypothetical protein Oant_1781 2 None None None 153008303 Common - putative transcriptional regulator, GntR family Oant_0968 224 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153007397 Pathogen - SH3 type 3 domain protein Oant_0052 4 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 153008590 Common - efflux transporter, RND family, MFP subunit Oant_1259 169 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 153007781 Common - major facilitator superfamily MFS_1 Oant_0436 187 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153008354 Common - hypothetical protein Oant_1019 19 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 153009984 Common - Electron-transferring-flavoprotein dehydrogenase Oant_2658 111 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 153007628 Pathogen - thiamine biosynthesis protein ThiS Oant_0283 2 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 153008256 Common - heavy metal translocating P-type ATPase Oant_0921 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 153007970 Common - binding-protein-dependent transport systems inner membrane component Oant_0627 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153007612 Common - two component transcriptional regulator, LuxR family Oant_0267 160 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 153007474 Common - PfkB domain protein Oant_0129 128 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153009020 Common - hypothetical protein Oant_1690 5 None None None 153008039 Pathogen - hypothetical protein Oant_0701 1 None None None 153009666 Common - protein of unknown function DUF815 Oant_2338 89 COG2607 COG2607, Predicted ATPase (AAA+ superfamily) General function prediction only 153008820 Pathogen - hypothetical protein Oant_1489 1 None None None 153009874 Common - 3-demethylubiquinone-9 3-methyltransferase Oant_2547 65 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 153008428 Common - alanine racemase domain protein Oant_1094 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 153008087 Common - tRNA (guanine-N(7)-)-methyltransferase Oant_0751 166 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 153010006 Common - hypothetical protein Oant_2680 6 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 153008828 Common - hypothetical protein Oant_1497 5 None None None 153009394 Pathogen - hypothetical protein Oant_2064 2 None None None 153009535 Common - ATP-dependent Clp protease, ATP-binding subunit ClpX Oant_2205 227 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 153007538 Common - Stress responsive alpha-beta barrel domain protein Oant_0193 9 None None None 153007999 Pathogen - hypothetical protein Oant_0660 1 None None None 153007635 Common - Monosaccharide-transporting ATPase Oant_0290 130 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 153007621 Common - ABC transporter related Oant_0276 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153009571 Common - valyl-tRNA synthetase Oant_2241 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153008950 Common - tRNA/rRNA methyltransferase (SpoU) Oant_1620 167 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 153009428 Common - glutamyl-tRNA synthetase Oant_2098 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 153007888 Common - SNARE associated Golgi protein Oant_0543 43 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 153008279 Common - tRNA (guanine-N1)-methyltransferase Oant_0944 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 153009401 Common - signal transduction histidine kinase, nitrogen specific, NtrB Oant_2071 223 COG3852 NtrB, Signal transduction histidine kinase, nitrogen specific Signal transduction mechanisms 153008761 Common - NMT1/THI5 like domain protein Oant_1430 109 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 153007515 Common - RNA polymerase, sigma 54 subunit, RpoN Oant_0170 144 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 153007602 Common - hypothetical protein Oant_0257 5 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 153008727 Common - lipoprotein, YaeC family Oant_1396 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 153009174 Common - phage integrase family protein Oant_1844 111 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153008880 Common - hypothetical protein Oant_1550 5 None None None 153008065 Common - Tetratricopeptide TPR_2 repeat protein Oant_0729 86 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 153010017 Common - Oligopeptidase B Oant_2691 110 COG1770 PtrB, Protease II Amino acid transport and metabolism 153009831 Common - hypothetical protein Oant_2504 10 COG5653 COG5653, Protein involved in cellulose biosynthesis (CelD) Cell envelope biogenesis, outer membrane 153007820 Pathogen - hypothetical protein Oant_0475 1 None None None 153009463 Common - Xanthine phosphoribosyltransferase Oant_2133 84 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 153008962 Common - hypothetical protein Oant_1632 29 COG0433 COG0433, Predicted ATPase General function prediction only 153009866 Common - DNA topoisomerase IV, A subunit Oant_2539 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 153007504 Common - DNA mismatch repair protein MutS Oant_0159 201 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 153008349 Common - hypothetical protein Oant_1014 3 None None None 153009423 Common - hypothetical protein Oant_2093 12 COG3184 COG3184, Uncharacterized protein conserved in bacteria Function unknown 153008117 Common - putative DNA-B helicase protein Oant_0781 21 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 153009328 Common - hypothetical protein Oant_1998 5 None None None 153008983 Common - excinuclease ABC, B subunit Oant_1653 226 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 153007892 Common - deoxyxylulose-5-phosphate synthase Oant_0547 225 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 153008522 Common - hypothetical protein Oant_1191 11 None None None 153007771 Common - pantoate--beta-alanine ligase Oant_0426 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 153009262 Common - hypothetical protein Oant_1932 9 None None None 153007914 Common - ribosomal protein S6 Oant_0569 203 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 153008218 Common - phage integrase family protein Oant_0882 66 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 153009863 Common - Porphobilinogen synthase Oant_2536 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 153010033 Common - GreA/GreB family elongation factor Oant_2707 119 COG0782 GreA, Transcription elongation factor Transcription 153007931 Common - cytochrome c oxidase subunit III Oant_0586 159 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 153007986 Common - hypothetical protein Oant_0644 14 None None None 153010077 Common - hypothetical protein Oant_2753 8 None None None 153009823 Common - ribosomal protein S9 Oant_2496 248 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 153009257 Common - hypothetical protein Oant_1927 21 None None None 153009040 Common - PhnA protein Oant_1710 105 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 153009432 Common - Citrate synthase Oant_2102 128 COG0372 GltA, Citrate synthase Energy production and conversion 153009851 Common - V-type H(+)-translocating pyrophosphatase Oant_2524 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 153008654 Common - phospholipase D/Transphosphatidylase Oant_1323 150 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 153009773 Common - protein of unknown function DUF900 hydrolase family protein Oant_2445 23 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 153008405 Common - hypothetical protein Oant_1071 3 None None None 153008224 Common - phage tail tape measure protein, TP901 family Oant_0888 35 COG5271 MDN1, AAA ATPase containing von Willebrand factor type A (vWA) domain General function prediction only 153009126 Common - hypothetical protein Oant_1796 4 COG3242 COG3242, Uncharacterized protein conserved in bacteria Function unknown 153008773 Common - aminotransferase class-III Oant_1442 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 153008246 Common - protein of unknown function DUF21 Oant_0911 219 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 153007827 Common - regulatory protein ArsR Oant_0482 131 COG0640 ArsR, Predicted transcriptional regulators Transcription 153007713 Common - carbon monoxide dehydrogenase subunit G Oant_0368 38 COG3427 COG3427, Uncharacterized conserved protein Function unknown 153007509 Common - hypothetical protein Oant_0164 7 None None None 153007409 Common - protein of unknown function DUF59 Oant_0064 231 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 153009383 Common - ErfK/YbiS/YcfS/YnhG family protein Oant_2053 83 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153009136 Common - Lysine exporter protein (LYSE/YGGA) Oant_1806 61 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 153009163 Common - ABC transporter related Oant_1833 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153009757 Common - TRAP transporter solute receptor, TAXI family Oant_2429 97 COG2358 Imp, TRAP-type uncharacterized transport system, periplasmic component General function prediction only 153008712 Common - 6-aminohexanoate-dimer hydrolase Oant_1381 78 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 153008043 Common - Integrase catalytic region Oant_0706 72 COG4584 COG4584, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009378 Common - Indole-3-glycerol-phosphate synthase Oant_2048 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 153009481 Common - hypothetical protein Oant_2151 86 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 153009988 Common - aminopeptidase N Oant_2662 161 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 153008032 Common - BioY protein Oant_0693 102 COG1268 BioY, Uncharacterized conserved protein General function prediction only 153009441 Common - hypothetical protein Oant_2111 142 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 153008446 Common - inner-membrane translocator Oant_1112 150 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 153009081 Common - UDP-3-0-acyl N-acetylglucosamine deacetylase Oant_1751 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 153009585 Common - FeS assembly protein SufB Oant_2255 186 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 153008797 Common - RNA binding S1 domain protein Oant_1466 145 COG2183 Tex, Transcriptional accessory protein Transcription 153009801 Common - MmgE/PrpD family protein Oant_2474 48 COG2079 PrpD, Uncharacterized protein involved in propionate catabolism General function prediction only 153007656 Common - binding-protein-dependent transport systems inner membrane component Oant_0311 207 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153010026 Common - haloacid dehalogenase, type II Oant_2700 53 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 153008631 Pathogen - hypothetical protein Oant_1300 1 None None None 153008901 Common - hypothetical protein Oant_1571 28 COG5385 COG5385, Uncharacterized protein conserved in bacteria Function unknown 153009179 Common - hypothetical protein Oant_1849 2 None None None 153009768 Common - Urea transporter Oant_2440 20 COG4413 Utp, Urea transporter Amino acid transport and metabolism 153007596 Common - hypothetical protein Oant_0251 18 COG5281 COG5281, Phage-related minor tail protein Function unknown 153009391 Common - pyruvate dehydrogenase complex dihydrolipoamide acetyltransferase Oant_2061 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 153008158 Common - adenosylhomocysteinase Oant_0822 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 153009832 Common - exopolysaccharide transport protein family Oant_2505 74 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 153008719 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Oant_1388 162 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 153008874 Common - hypothetical protein Oant_1544 12 None None None 153008164 Common - two component transcriptional regulator, winged helix family Oant_0828 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153007832 Common - hypothetical protein Oant_0487 37 COG4649 COG4649, Uncharacterized protein conserved in bacteria Function unknown 153009339 Common - hypothetical protein Oant_2009 15 COG5330 COG5330, Uncharacterized protein conserved in bacteria Function unknown 153009095 Common - serine/threonine protein kinase Oant_1765 10 COG2112 COG2112, Predicted Ser/Thr protein kinase Signal transduction mechanisms 153008377 Common - GCN5-related N-acetyltransferase Oant_1043 21 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153008327 Common - Prephenate dehydrogenase Oant_0992 160 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 153007684 Common - Deoxyribodipyrimidine photo-lyase Oant_0339 139 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 153007365 Common - histidine triad (HIT) protein Oant_0020 54 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 153009627 Common - phage-related tail fibre protein-like protein Oant_2297 21 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 153008386 Common - GCN5-related N-acetyltransferase Oant_1052 115 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153009293 Common - ribosomal protein L16 Oant_1963 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 153009956 Common - holo-acyl-carrier-protein synthase Oant_2629 160 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 153009880 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_2553 25 None None None 153009498 Pathogen - hypothetical protein Oant_2168 1 None None None 153009005 Common - hypothetical protein Oant_1675 21 COG5500 COG5500, Predicted integral membrane protein Function unknown 153007925 Common - Invasion associated locus B family protein Oant_0580 13 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 153009672 Common - twin-arginine translocation protein, TatB subunit Oant_2344 29 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 153009918 Common - molybdopterin converting factor, subunit 1 Oant_2591 77 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 153008595 Common - hypothetical protein Oant_1264 8 None None None 153009932 Common - 4-hydroxythreonine-4-phosphate dehydrogenase Oant_2605 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 153008599 Common - GCN5-related N-acetyltransferase Oant_1268 135 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 153009043 Common - protein of unknown function DUF1498 Oant_1713 18 COG3822 COG3822, ABC-type sugar transport system, auxiliary component General function prediction only 153008809 Common - SEC-independent protein translocase protein TatC Oant_1478 45 COG2346 COG2346, Truncated hemoglobins General function prediction only 153009609 Common - glutamyl-tRNA(Gln) amidotransferase, B subunit Oant_2279 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 153008287 Common - Succinate dehydrogenase hydrophobic membrane anchor Oant_0952 44 COG2142 SdhD, Succinate dehydrogenase, hydrophobic anchor subunit Energy production and conversion 153007444 Common - protein of unknown function DUF214 Oant_0099 86 COG3127 COG3127, Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, permease component Secondary metabolites biosynthesis, transport, and catabolism 153009466 Common - flavoprotein WrbA Oant_2136 95 COG0655 WrbA, Multimeric flavodoxin WrbA General function prediction only 153009357 Common - Endoribonuclease L-PSP Oant_2027 91 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 153009105 Common - drug resistance transporter, Bcr/CflA subfamily Oant_1775 213 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153008752 Common - Dihydroxy-acid dehydratase Oant_1421 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 153009695 Common - protein of unknown function DUF1045 Oant_2367 27 None None None 153009701 Common - Beta-ketoacyl synthase Oant_2373 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153008616 Common - transcriptional regulator, GntR family Oant_1285 132 COG1802 GntR, Transcriptional regulators Transcription 153008338 Common - protein of unknown function DUF6 transmembrane Oant_1003 106 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 153008589 Common - ABC transporter related Oant_1258 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 153007599 Common - hypothetical protein Oant_0254 15 None None None 153008440 Common - ATP synthase F1, epsilon subunit Oant_1106 169 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 153009121 Common - hypothetical protein Oant_1791 15 None None None 153010007 Common - protein of unknown function DUF1491 Oant_2681 20 COG5447 COG5447, Uncharacterized conserved protein Function unknown 153008449 Common - ABC transporter related Oant_1115 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153008362 Common - Methyltransferase type 11 Oant_1027 75 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153009147 Common - Endonuclease/exonuclease/phosphatase Oant_1817 11 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 153009212 Common - precorrin-3B C17-methyltransferase, putative Oant_1882 7 COG2073 CbiG, Cobalamin biosynthesis protein CbiG Coenzyme metabolism 153007812 Common - Cbb3-type cytochrome oxidase component Oant_0467 5 COG4736 CcoQ, Cbb3-type cytochrome oxidase, subunit 3 Posttranslational modification, protein turnover, chaperones 153008506 Common - Quinone oxidoreductase putative PIG3 Oant_1174 189 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 153009140 Common - Pyridoxal phosphate biosynthetic protein PdxJ Oant_1810 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 153008379 Common - diguanylate cyclase with PAS/PAC sensor Oant_1045 183 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153008176 Common - hypothetical protein Oant_0840 11 None None None 153009382 Common - preprotein translocase, SecG subunit Oant_2052 14 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 153009745 Common - NADH-quinone oxidoreductase, chain G Oant_2417 190 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 153007354 Common - protein of unknown function DUF126 Oant_0009 35 COG1786 COG1786, Uncharacterized conserved protein Function unknown 153007417 Common - hypothetical protein Oant_0072 80 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 153008997 Common - binding-protein-dependent transport systems inner membrane component Oant_1667 135 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153009154 Common - ABC transporter related Oant_1824 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 153008074 Common - ferric uptake regulator, Fur family Oant_0738 139 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 153008142 Common - hypothetical protein Oant_0806 15 None None None 153009635 Common - hypothetical protein Oant_2305 8 COG5471 COG5471, Uncharacterized conserved protein Function unknown 153009343 Common - protein of unknown function DUF1624 Oant_2013 27 COG3503 COG3503, Predicted membrane protein Function unknown 153007826 Common - conserved hypothethetical protein Oant_0481 8 COG3832 COG3832, Uncharacterized conserved protein Function unknown 153010049 Common - transposase IS3/IS911 family protein Oant_2724 24 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009188 Common - hypothetical protein Oant_1858 55 COG0392 COG0392, Predicted integral membrane protein Function unknown 153008315 Common - major facilitator superfamily MFS_1 Oant_0980 138 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 153008827 Common - hypothetical protein Oant_1496 6 None None None 153009315 Common - OmpA/MotB domain protein Oant_1985 169 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 153009949 Common - Glycine cleavage T-protein barrel Oant_2622 121 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 153007819 Common - DSBA oxidoreductase Oant_0474 91 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 153009791 Common - hypothetical protein Oant_2464 6 None None None 153008998 Common - binding-protein-dependent transport systems inner membrane component Oant_1668 147 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153008147 Pathogen - hypothetical protein Oant_0811 2 None None None 153009735 Common - Methylmalonyl-CoA epimerase Oant_2407 89 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 153008698 Common - Ferric reductase domain protein transmembrane component Oant_1367 79 COG2717 COG2717, Predicted membrane protein Function unknown 153008140 Common - hypothetical protein Oant_0804 48 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153009059 Pathogen - hypothetical protein Oant_1729 1 None None None 153009360 Common - translation elongation factor Ts Oant_2030 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 153009067 Common - hypothetical protein Oant_1737 15 COG5462 COG5462, Predicted secreted (periplasmic) protein Function unknown 153009661 Common - gid protein Oant_2333 100 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 153007427 Common - hypothetical protein Oant_0082 3 None None None 153008016 Common - type IV secretion/conjugal transfer ATPase, VirB4 family Oant_0677 64 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 153008023 Common - conjugation TrbI family protein Oant_0684 59 COG2948 VirB10, Type IV secretory pathway, VirB10 components Intracellular trafficking and secretion 153008733 Common - branched-chain amino acid ABC transporter, periplasmic amino acid- binding protein Oant_1402 89 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 153009810 Common - binding-protein-dependent transport systems inner membrane component Oant_2483 155 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153008473 Common - peptidase M48 Ste24p Oant_1139 129 COG4784 COG4784, Putative Zn-dependent protease General function prediction only 153007569 Common - hypothetical protein Oant_0224 2 None None None 153008007 Common - putative transcriptional regulator, XRE family Oant_0668 5 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 153009077 Common - D-alanine--D-alanine ligase Oant_1747 210 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 153009943 Common - hypothetical protein Oant_2616 6 None None None 153007497 Common - ErfK/YbiS/YcfS/YnhG family protein Oant_0152 73 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 153007432 Common - Antibiotic biosynthesis monooxygenase Oant_0087 24 COG1359 COG1359, Uncharacterized conserved protein Function unknown 153007425 Common - hypothetical protein Oant_0080 67 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 153007948 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Oant_0603 166 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 153008867 Common - single-strand binding protein Oant_1537 203 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 153009500 Common - acyl-CoA dehydrogenase domain protein Oant_2170 157 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 153009927 Common - Leucyl aminopeptidase Oant_2600 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 153007788 Common - two component transcriptional regulator, LuxR family Oant_0443 202 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 153007457 Common - dihydroxy-acid dehydratase Oant_0112 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 153007749 Common - Dihydroorotate oxidase Oant_0404 231 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 153009389 Common - dehydrogenase E1 component Oant_2059 169 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 153008425 Common - protein of unknown function DUF1674 Oant_1091 4 COG5508 COG5508, Uncharacterized conserved small protein Function unknown 153007764 Pathogen - hypothetical protein Oant_0419 2 None None None 153008986 Common - Extensin family protein Oant_1656 36 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 153008534 Common - OmpA/MotB domain protein Oant_1203 158 COG1360 MotB, Flagellar motor protein Cell motility and secretion 153007848 Common - ATP synthase F0, B subunit Oant_0503 30 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 153007555 Pathogen - hypothetical protein Oant_0210 1 None None None 153008290 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_0955 64 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 153009075 Common - UDP-N-acetylmuramate--alanine ligase Oant_1745 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 153009559 Common - transcriptional regulator, MarR family Oant_2229 91 COG1846 MarR, Transcriptional regulators Transcription 153009376 Common - molybdenum cofactor synthesis domain protein Oant_2046 195 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 153007869 Common - Sua5/YciO/YrdC/YwlC family protein Oant_0524 232 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 153008090 Common - apolipoprotein N-acyltransferase Oant_0754 165 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 153009116 Pathogen - hypothetical protein Oant_1786 1 None None None 153010065 Common - metallophosphoesterase Oant_2741 34 COG0622 COG0622, Predicted phosphoesterase General function prediction only 153009593 Common - protein of unknown function DUF455 Oant_2263 48 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 153008633 Pathogen - hypothetical protein Oant_1302 1 None None None 153007562 Pathogen - hypothetical protein Oant_0217 1 None None None 153007726 Common - histidine kinase Oant_0381 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 153007452 Common - heme exporter protein CcmB Oant_0107 79 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 153008802 Common - Ornithine cyclodeaminase Oant_1471 82 COG2423 COG2423, Predicted ornithine cyclodeaminase, mu-crystallin homolog Amino acid transport and metabolism 153009514 Common - phosphonate ABC transporter, inner membrane subunit Oant_2184 88 COG3639 COG3639, ABC-type phosphate/phosphonate transport system, permease component Inorganic ion transport and metabolism 153009124 Common - HflK protein Oant_1794 185 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 153008058 Common - SAF domain protein Oant_0722 55 COG3745 CpaB, Flp pilus assembly protein CpaB Intracellular trafficking and secretion 153009819 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Oant_2492 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 153007730 Common - hypothetical protein Oant_0385 5 None None None 153008236 Common - amidohydrolase Oant_0901 168 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 153008274 Pathogen - hypothetical protein Oant_0939 1 None None None 153008926 Common - putative transcriptional regulator, AsnC family Oant_1596 160 COG1522 Lrp, Transcriptional regulators Transcription 153007842 Common - glutathione-dependent formaldehyde-activating GFA Oant_0497 63 COG3791 COG3791, Uncharacterized conserved protein Function unknown 153008101 Common - cell wall hydrolase SleB Oant_0765 24 COG3773 SleB, Cell wall hydrolyses involved in spore germination Cell envelope biogenesis, outer membrane 153008392 Common - iojap-like protein Oant_1058 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 153008780 Common - oxidoreductase alpha (molybdopterin) subunit Oant_1449 171 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 153008089 Common - transcriptional regulator, XRE family Oant_0753 41 COG1396 HipB, Predicted transcriptional regulators Transcription 153007867 Common - glycyl-tRNA synthetase, beta subunit Oant_0522 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 153007792 Common - porin Oant_0447 14 None None None 153008839 Pathogen - hypothetical protein Oant_1509 1 None None None 153009767 Common - Urease accessory protein UreF Oant_2439 78 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 153009483 Common - hypothetical protein Oant_2153 13 None None None 153007976 Common - PilT protein domain protein Oant_0633 17 COG3742 COG3742, Uncharacterized protein conserved in bacteria Function unknown 153009274 Common - ribosomal protein L1 Oant_1944 238 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 153008935 Common - GCN5-related N-acetyltransferase Oant_1605 92 COG3153 COG3153, Predicted acetyltransferase General function prediction only 153009684 Common - Sel1 domain protein repeat-containing protein Oant_2356 71 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 153008189 Common - protein of unknown function DUF299 Oant_0853 112 COG1806 COG1806, Uncharacterized protein conserved in bacteria Function unknown 153007904 Common - short-chain dehydrogenase/reductase SDR Oant_0559 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153009228 Common - Precorrin-8X methylmutase Oant_1898 119 COG2082 CobH, Precorrin isomerase Coenzyme metabolism 153009446 Common - dihydroneopterin aldolase Oant_2116 76 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 153009231 Common - Siderophore-interacting protein Oant_1901 61 COG2375 ViuB, Siderophore-interacting protein Inorganic ion transport and metabolism 153008686 Common - conserved hypothetical protein 730 Oant_1355 106 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 153008580 Common - signal transduction histidine kinase Oant_1249 93 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 153007640 Common - putative transcriptional regulator, MerR family Oant_0295 130 COG0789 SoxR, Predicted transcriptional regulators Transcription 153009726 Common - hypothetical protein Oant_2398 3 None None None 153008494 Pathogen - conserved hypothetical cytosolic protein Oant_1162 2 COG3750 COG3750, Uncharacterized protein conserved in bacteria Function unknown 153007799 Common - transcriptional regulator, LysR family Oant_0454 157 COG0583 LysR, Transcriptional regulator Transcription 153009472 Common - Rhodanese domain protein Oant_2142 145 COG2897 SseA, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 153007525 Common - Ribulose-phosphate 3-epimerase Oant_0180 231 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 153009754 Common - transcriptional regulator, TetR family Oant_2426 104 COG1309 AcrR, Transcriptional regulator Transcription 153010040 Common - mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase Oant_2715 164 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 153007984 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Oant_0642 145 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 153008125 Common - chaperone protein DnaJ Oant_0789 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 153009977 Common - hypothetical protein Oant_2650 9 None None None 153009668 Common - Protein-L-isoaspartate(D-aspartate) O-methyltransferase Oant_2340 151 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 153007754 Common - integral membrane sensor hybrid histidine kinase Oant_0409 226 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 153007369 Common - lytic murein transglycosylase Oant_0024 104 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 153009219 Common - cobyrinic acid a,c-diamide synthase Oant_1889 140 COG1797 CobB, Cobyrinic acid a,c-diamide synthase Coenzyme metabolism 153008184 Common - protein-export protein SecB Oant_0848 107 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 153008815 Common - chitinase-like protein Oant_1484 25 COG3179 COG3179, Predicted chitinase General function prediction only 153008749 Common - periplasmic binding protein/LacI transcriptional regulator Oant_1418 114 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153007687 Common - acriflavin resistance protein Oant_0342 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 153007966 Common - hypothetical protein Oant_0623 4 None None None 153008856 Common - hypothetical protein Oant_1526 2 None None None 153009479 Common - UDP-glucose 4-epimerase Oant_2149 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 153009970 Common - hypothetical protein Oant_2643 20 COG3743 COG3743, Uncharacterized conserved protein Function unknown 153009567 Common - polar amino acid ABC transporter, inner membrane subunit Oant_2237 173 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 153009279 Common - hypothetical protein Oant_1949 4 None None None 153009982 Common - AMP nucleosidase Oant_2656 54 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 153009012 Common - major facilitator superfamily MFS_1 Oant_1682 229 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153009191 Pathogen - hypothetical protein Oant_1861 2 None None None 153007383 Common - Propionyl-CoA carboxylase Oant_0038 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 153008734 Common - transcriptional regulator, LysR family Oant_1403 155 COG0583 LysR, Transcriptional regulator Transcription 153009198 Pathogen - Entericidin EcnAB Oant_1868 2 COG5510 COG5510, Predicted small secreted protein Function unknown 153009542 Common - GCN5-related N-acetyltransferase Oant_2212 69 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 153008475 Common - thiamine ABC transporter, inner membrane subunit Oant_1141 60 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 153008419 Common - major facilitator superfamily MFS_1 Oant_1085 74 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 153007472 Common - Methyltransferase type 11 Oant_0127 130 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153008669 Common - Glutathione S-transferase domain protein Oant_1338 90 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153008585 Common - TonB-system energizer ExbB type-1 Oant_1254 149 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 153009280 Pathogen - hypothetical protein Oant_1950 2 None None None 153009621 Common - phage P2 GpU family protein Oant_2291 27 COG3499 COG3499, Phage protein U General function prediction only 153007587 Pathogen - hypothetical protein Oant_0242 1 None None None 153009285 Common - ribosomal protein S10 Oant_1955 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 153009905 Common - protein of unknown function DUF992 Oant_2578 12 None None None 153007769 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_0424 36 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 153008410 Common - L-lactate permease Oant_1076 103 COG1620 LldP, L-lactate permease Energy production and conversion 153007705 Common - transcriptional regulator, GntR family Oant_0360 104 COG1802 GntR, Transcriptional regulators Transcription 153008846 Pathogen - hypothetical protein Oant_1516 1 None None None 153009847 Common - fatty acid/phospholipid synthesis protein PlsX Oant_2520 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 153007580 Common - hypothetical protein Oant_0235 11 COG1403 McrA, Restriction endonuclease Defense mechanisms 153009011 Common - protein of unknown function zinc metallopeptidase putative Oant_1681 88 COG2321 COG2321, Predicted metalloprotease General function prediction only 153009036 Common - protein of unknown function DUF475 Oant_1706 39 COG2899 COG2899, Uncharacterized protein conserved in bacteria Function unknown 153007547 Common - 3'(2'),5'-bisphosphate nucleotidase Oant_0202 183 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 153007945 Common - lipoprotein, putative Oant_0600 11 None None None 153008729 Common - inner-membrane translocator Oant_1398 66 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 153007698 Common - binding-protein-dependent transport systems inner membrane component Oant_0353 181 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 153009206 Common - cobalamin biosynthesis protein CobW Oant_1876 127 COG0523 COG0523, Putative GTPases (G3E family) General function prediction only 153007647 Common - sarcosine oxidase, delta subunit family Oant_0302 33 COG4311 SoxD, Sarcosine oxidase delta subunit Amino acid transport and metabolism 153009647 Pathogen - hypothetical protein Oant_2319 1 None None None 153007915 Common - malonyl CoA-acyl carrier protein transacylase Oant_0570 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 153008149 Common - acetyl-CoA carboxylase, carboxyl transferase, beta subunit Oant_0813 217 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 153008011 Common - hypothetical protein Oant_0672 6 None None None 153009904 Common - phosphoribosylglycinamide formyltransferase Oant_2577 220 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 153009418 Common - nitrogen regulatory protein P-II Oant_2088 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 153008462 Common - ribosomal protein L32 Oant_1128 120 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 153008674 Common - protein of unknown function DUF195 Oant_1343 143 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 153008307 Common - YCII-related Oant_0972 20 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 153008461 Common - monofunctional biosynthetic peptidoglycan transglycosylase Oant_1127 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 153009180 Common - periplasmic protein-like protein Oant_1850 6 COG3904 COG3904, Predicted periplasmic protein Function unknown 153007609 Pathogen - hypothetical protein Oant_0264 1 None None None 153008241 Common - acetyl-CoA carboxylase, carboxyl transferase, alpha subunit Oant_0906 182 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 153009644 Common - hypothetical protein Oant_2316 2 None None None 153008456 Common - 3-hydroxybutyrate dehydrogenase Oant_1122 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153008898 Common - hypothetical protein Oant_1568 13 None None None 153007375 Common - cytidylate kinase Oant_0030 206 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 153009818 Common - protein of unknown function DUF861 cupin_3 Oant_2491 32 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 153008754 Common - KDPG and KHG aldolase Oant_1423 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 153008329 Common - Methyltransferase type 11 Oant_0994 70 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153009879 Common - GCN5-related N-acetyltransferase Oant_2552 30 COG2153 ElaA, Predicted acyltransferase General function prediction only 153009947 Common - YCII-related Oant_2620 39 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 153008841 Common - ParB domain protein nuclease Oant_1511 32 COG1475 Spo0J, Predicted transcriptional regulators Transcription 153009086 Common - AzlC family protein Oant_1756 104 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 153008638 Pathogen - hypothetical protein Oant_1307 1 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 153008389 Common - glutamate 5-kinase Oant_1055 193 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 153008320 Common - protein of unknown function DUF214 Oant_0985 34 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 153009872 Common - hypothetical protein Oant_2545 14 COG4391 COG4391, Uncharacterized protein conserved in bacteria Function unknown 153008660 Common - phosphoglycerate mutase 1 family Oant_1329 181 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 153007480 Common - 3'-5' exonuclease Oant_0135 109 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 153007688 Common - NMT1/THI5 like domain protein Oant_0343 78 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 153008404 Common - Alcohol dehydrogenase zinc-binding domain protein Oant_1070 97 COG2130 COG2130, Putative NADP-dependent oxidoreductases General function prediction only 153009821 Common - thioesterase superfamily protein Oant_2494 59 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 153009696 Common - PfkB domain protein Oant_2368 93 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153009804 Common - PfkB domain protein Oant_2477 101 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153009224 Common - phospholipase/Carboxylesterase Oant_1894 6 COG0400 COG0400, Predicted esterase General function prediction only 153009204 Common - cobalt transporter, subunit CbtA Oant_1874 13 COG5446 COG5446, Predicted integral membrane protein Function unknown 153008468 Common - transcriptional regulator, CarD family Oant_1134 83 COG1329 COG1329, Transcriptional regulators, similar to M. xanthus CarD Transcription 153009841 Common - ATP synthase F0, A subunit Oant_2514 191 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 153009892 Common - SH3 type 3 domain protein Oant_2565 15 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 153008026 Common - polysaccharide deacetylase Oant_0687 25 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 153008930 Common - lipoprotein, putative Oant_1600 6 None None None 153007927 Common - Cytochrome c oxidase subunit I type Oant_0582 167 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 153008103 Common - phosphate uptake regulator, PhoU Oant_0767 196 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 153009250 Common - single-stranded-DNA-specific exonuclease RecJ Oant_1920 194 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 153009838 Common - protein of unknown function UPF0060 Oant_2511 65 COG1742 COG1742, Uncharacterized conserved protein Function unknown 153008939 Common - ATPase associated with various cellular activities AAA_3 Oant_1609 172 COG0714 COG0714, MoxR-like ATPases General function prediction only 153009049 Common - Trans-aconitate 2-methyltransferase Oant_1719 107 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 153009524 Common - phosphonate metabolism Oant_2194 45 COG3626 PhnI, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 153009492 Pathogen - hypothetical protein Oant_2162 1 None None None 153008443 Common - transcriptional regulator, GntR family Oant_1109 122 COG1802 GntR, Transcriptional regulators Transcription 153008533 Common - lipid A ABC exporter family, fused ATPase and inner membrane subunits Oant_1202 248 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 153009107 Common - hypothetical protein Oant_1777 2 None None None 153008426 Common - acetate--CoA ligase Oant_1092 212 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 153009355 Common - protein of unknown function DUF482 Oant_2025 81 COG3146 COG3146, Uncharacterized protein conserved in bacteria Function unknown 153007659 Common - protein of unknown function DUF718 Oant_0314 36 COG3254 COG3254, Uncharacterized conserved protein Function unknown 153007407 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_0062 110 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 153007681 Common - UreE urease accessory domain protein Oant_0336 60 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 153007691 Common - ABC transporter related Oant_0346 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 153009411 Common - beta-lactamase domain protein Oant_2081 81 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 153007743 Common - O-succinylhomoserine sulfhydrylase Oant_0398 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 153008438 Common - ATP synthase F1, gamma subunit Oant_1104 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 153009793 Common - Integrase catalytic region Oant_2466 142 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 153010066 Common - transposase IS3/IS911 family protein Oant_2742 21 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 153008592 Common - hypothetical protein Oant_1261 17 COG4655 COG4655, Predicted membrane protein Function unknown 153010004 Common - protein of unknown function DUF1214 Oant_2678 17 COG5402 COG5402, Uncharacterized conserved protein Function unknown 153008656 Common - aldehyde dehydrogenase Oant_1325 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153008772 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Oant_1441 170 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153008891 Common - hypothetical protein Oant_1561 8 None None None 153009138 Common - exodeoxyribonuclease V Oant_1808 110 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 153008710 Common - short-chain dehydrogenase/reductase SDR Oant_1379 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153009976 Common - protein of unknown function DUF423 Oant_2649 10 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 153008197 Common - Cobyrinic acid ac-diamide synthase Oant_0861 202 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 153007702 Common - Pyridoxal 4-dehydrogenase Oant_0357 132 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 153007595 Common - hypothetical protein Oant_0250 3 None None None 153008211 Common - glucose-methanol-choline oxidoreductase Oant_0875 88 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 153008775 Common - FAD dependent oxidoreductase Oant_1444 145 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153007719 Common - transcriptional regulator, TetR family Oant_0374 39 COG1309 AcrR, Transcriptional regulator Transcription 153009090 Common - electron transport protein SCO1/SenC Oant_1760 99 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 153007479 Common - acyltransferase 3 Oant_0134 26 COG4763 COG4763, Predicted membrane protein Function unknown 153009680 Common - putative deoxyguanosinetriphosphate triphosphohydrolase Oant_2352 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 153007350 Common - DNA replication and repair protein RecF Oant_0005 156 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 153008203 Common - protein of unknown function DUF534 Oant_0867 55 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 153009439 Common - Mammalian cell entry related domain protein Oant_2109 66 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 153008235 Common - transposase IS3/IS911 family protein Oant_0900 17 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009996 Common - CcmE/CycJ protein Oant_2670 89 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 153009409 Common - methionyl-tRNA synthetase Oant_2079 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153007517 Common - PTS IIA-like nitrogen-regulatory protein PtsN Oant_0172 139 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 153009125 Common - HflC protein Oant_1795 120 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 153007502 Common - metal dependent phosphohydrolase Oant_0157 126 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 153007775 Common - L-aspartate oxidase Oant_0430 225 COG0029 NadB, Aspartate oxidase Coenzyme metabolism 153009168 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Oant_1838 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153007856 Pathogen - hypothetical protein Oant_0511 2 None None None 153009592 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Oant_2262 221 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 153010071 Common - GtrA family protein Oant_2747 12 COG2246 COG2246, Predicted membrane protein Function unknown 153008263 Common - outer membrane lipoprotein omp19 Oant_0928 8 None None None 153009400 Common - putative TIM-barrel protein, nifR3 family Oant_2070 206 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 153008905 Common - protein of unknown function DUF1153 Oant_1575 27 None None None 153009708 Common - HpcH/HpaI aldolase Oant_2380 74 COG3836 HpcH, 2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase Carbohydrate transport and metabolism 153009195 Common - transcriptional regulator, AraC family Oant_1865 147 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 153009295 Common - ribosomal protein S17 Oant_1965 219 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 153008520 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Oant_1189 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 153008872 Pathogen - hypothetical protein Oant_1542 1 None None None 153007916 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Oant_0571 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153009861 Common - hypothetical protein Oant_2534 12 None None None 153008900 Common - response regulator receiver protein Oant_1570 62 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 153008798 Common - regulatory protein ArsR Oant_1467 49 COG0640 ArsR, Predicted transcriptional regulators Transcription 153007487 Common - protein of unknown function DUF1345 Oant_0142 40 COG4291 COG4291, Predicted membrane protein Function unknown 153009725 Common - Extensin family protein Oant_2397 36 COG3921 COG3921, Uncharacterized protein conserved in bacteria Function unknown 153009652 Common - hypothetical protein Oant_2324 80 COG5164 SPT5, Transcription elongation factor Transcription 153009628 Common - phage tail protein I Oant_2298 27 COG4385 gpI, Bacteriophage P2-related tail formation protein General function prediction only 153008139 Common - translation initiation factor IF-3 Oant_0803 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 153008971 Common - Protein of unknown function DUF1790 Oant_1641 34 COG5465 COG5465, Uncharacterized conserved protein Function unknown 153008091 Common - CBS domain containing protein Oant_0755 216 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 153009550 Common - diguanylate cyclase Oant_2220 186 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 153009665 Common - preprotein translocase, YajC subunit Oant_2337 58 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 153007507 Common - tRNA/rRNA methyltransferase (SpoU) Oant_0162 214 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 153008981 Common - Lytic transglycosylase catalytic Oant_1651 44 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 153007396 Common - Cytochrome o ubiquinol oxidase subunit IV Oant_0051 61 COG3125 CyoD, Heme/copper-type cytochrome/quinol oxidase, subunit 4 Energy production and conversion 153007763 Common - protein of unknown function DUF1127 Oant_0418 6 COG5457 COG5457, Uncharacterized conserved small protein Function unknown 153008370 Common - PTSINtr with GAF domain, PtsP Oant_1035 235 COG3605 PtsP, Signal transduction protein containing GAF and PtsI domains Signal transduction mechanisms 153007622 Common - aldehyde dehydrogenase Oant_0277 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 153009334 Common - protein of unknown function DUF955 Oant_2004 52 COG3800 COG3800, Predicted transcriptional regulator General function prediction only 153008081 Common - tRNA pseudouridine synthase B Oant_0745 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 153007871 Common - hypothetical protein Oant_0526 10 None None None 153007673 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Oant_0328 210 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 153009350 Common - ATP-dependent Clp protease adaptor protein ClpS Oant_2020 121 COG2127 COG2127, Uncharacterized conserved protein Function unknown 153009133 Common - protein of unknown function DUF87 Oant_1803 77 COG0433 COG0433, Predicted ATPase General function prediction only 153008244 Common - Shikimate kinase Oant_0909 196 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 153007990 Pathogen - Conjugal transfer TraD family protein Oant_0648 1 None None None 153009967 Common - SsrA-binding protein Oant_2640 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 153009547 Common - ABC transporter related Oant_2217 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 153008956 Common - adenine phosphoribosyltransferase Oant_1626 187 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 153007404 Common - hypothetical protein Oant_0059 5 None None None 153009456 Common - low temperature requirement A Oant_2126 31 COG4292 COG4292, Predicted membrane protein Function unknown 153008673 Common - conserved hypothetical selenoprotein Oant_1342 29 COG3526 COG3526, Uncharacterized protein conserved in bacteria Posttranslational modification, protein turnover, chaperones 153008927 Common - anthranilate synthase Oant_1597 237 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 153008132 Common - transcriptional regulator, TetR family Oant_0796 82 COG1309 AcrR, Transcriptional regulator Transcription 153007460 Common - putative transcriptional regulator, AsnC family Oant_0115 24 COG1522 Lrp, Transcriptional regulators Transcription 153008228 Common - hypothetical protein Oant_0892 5 None None None 153009057 Common - Methyltransferase type 12 Oant_1727 100 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 153008356 Common - preprotein translocase, SecA subunit Oant_1021 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 153007882 Common - metallophosphoesterase Oant_0537 47 COG0622 COG0622, Predicted phosphoesterase General function prediction only 153007391 Common - hypothetical protein Oant_0046 40 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 153008558 Common - Bile acid:sodium symporter Oant_1227 106 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 153007637 Common - Monosaccharide-transporting ATPase Oant_0292 107 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153009461 Common - ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent Oant_2131 184 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 153007805 Common - 2-hydroxy-3-oxopropionate reductase Oant_0460 169 COG2084 MmsB, 3-hydroxyisobutyrate dehydrogenase and related beta-hydroxyacid dehydrogenases Lipid metabolism 153008448 Common - ABC transporter related Oant_1114 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 153007876 Common - pyridoxamine 5'-phosphate oxidase Oant_0531 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 153007600 Common - hypothetical protein Oant_0255 3 None None None 153008567 Common - RNA polymerase, sigma 32 subunit, RpoH Oant_1236 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 153008967 Common - protein of unknown function DUF152 Oant_1637 182 COG1496 COG1496, Uncharacterized conserved protein Function unknown 153008791 Common - protein of unknown function DUF1338 Oant_1460 23 COG5383 COG5383, Uncharacterized protein conserved in bacteria Function unknown 153009367 Common - UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase Oant_2037 177 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 153009213 Common - major facilitator superfamily MFS_1 Oant_1883 179 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153008111 Common - rare lipoprotein A Oant_0775 137 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 153009887 Common - protein of unknown function UPF0118 Oant_2560 163 COG0628 PerM, Predicted permease General function prediction only 153008313 Common - HemY domain protein Oant_0978 26 COG3898 COG3898, Uncharacterized membrane-bound protein Function unknown 153008859 Common - deoxycytidine triphosphate deaminase Oant_1529 141 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 153009100 Common - hypothetical protein Oant_1770 24 COG4321 COG4321, Uncharacterized protein related to arylsulfate sulfotransferase involved in siderophore biosynthesis General function prediction only 153009215 Common - precorrin-4 C11-methyltransferase Oant_1885 201 COG2875 CobM, Precorrin-4 methylase Coenzyme metabolism 153009579 Common - DEAD/DEAH box helicase domain protein Oant_2249 241 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 153008021 Common - VirB8 family protein Oant_0682 38 COG3736 VirB8, Type IV secretory pathway, component VirB8 Intracellular trafficking and secretion 153008573 Pathogen - hypothetical protein Oant_1242 2 None None None 153008675 Common - peptide deformylase Oant_1344 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 153009277 Common - DNA-directed RNA polymerase, beta subunit Oant_1947 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 153008818 Common - Fels-2 prophage protein Oant_1487 24 COG3499 COG3499, Phage protein U General function prediction only 153009309 Common - ribosomal protein S11 Oant_1979 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 153008840 Common - DNA-cytosine methyltransferase Oant_1510 125 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 153009591 Common - hypothetical protein Oant_2261 32 COG2982 AsmA, Uncharacterized protein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 153008435 Common - hypothetical protein Oant_1101 6 None None None 153008234 Common - IS66 Orf2 family protein Oant_0899 45 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009659 Common - hypothetical protein Oant_2331 8 COG4872 COG4872, Predicted membrane protein Function unknown 153008416 Common - protein of unknown function DUF477 Oant_1082 91 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 153009580 Common - NAD(+) kinase Oant_2250 238 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 153007985 Common - transcriptional regulator, DeoR family Oant_0643 64 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 153008051 Common - Enoyl-CoA hydratase/isomerase Oant_0715 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 153009237 Common - peptidase M19 renal dipeptidase Oant_1907 104 COG2355 COG2355, Zn-dependent dipeptidase, microsomal dipeptidase homolog Amino acid transport and metabolism 153007969 Common - extracellular solute-binding protein family 5 Oant_0626 198 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 153009320 Common - regulatory protein ArsR Oant_1990 40 COG0640 ArsR, Predicted transcriptional regulators Transcription 153008583 Common - PRC-barrel domain protein Oant_1252 20 None None None 153009110 Pathogen - hypothetical protein Oant_1780 1 None None None 153009073 Common - cell division protein FtsW Oant_1743 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 153009026 Common - beta-Ig-H3/fasciclin Oant_1696 69 COG2335 COG2335, Secreted and surface protein containing fasciclin-like repeats Cell envelope biogenesis, outer membrane 153007943 Common - processing peptidase Oant_0598 201 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 153008565 Common - transcriptional regulator, AraC family Oant_1234 128 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 153008723 Common - TPR repeat-containing protein Oant_1392 166 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 153009842 Common - small multidrug resistance protein Oant_2515 147 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 153007469 Common - glycosyltransferase 36 Oant_0124 47 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 153008191 Common - conserved hypothetical protein 701 Oant_0855 97 COG1981 COG1981, Predicted membrane protein Function unknown 153009034 Common - hypothetical protein Oant_1704 17 None None None 153009019 Common - hypothetical protein Oant_1689 15 COG5453 COG5453, Uncharacterized conserved protein Function unknown 153009643 Common - hypothetical protein Oant_2315 4 None None None 153008459 Common - transcriptional regulator, HxlR family Oant_1125 128 COG1733 COG1733, Predicted transcriptional regulators Transcription 153009679 Common - arginyl-tRNA synthetase Oant_2351 247 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153008907 Pathogen - hypothetical protein Oant_1577 1 None None None 153008311 Common - Uroporphyrinogen III synthase HEM4 Oant_0976 20 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 153007752 Common - proline iminopeptidase Oant_0407 95 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 153009915 Common - short-chain dehydrogenase/reductase SDR Oant_2588 232 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153008049 Common - hypothetical protein Oant_0712 5 None None None 153008726 Common - ABC transporter related Oant_1395 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 153008348 Common - 3-hydroxybutyryl-CoA dehydrogenase Oant_1013 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 153008622 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Oant_1291 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153007475 Common - short-chain dehydrogenase/reductase SDR Oant_0130 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153008341 Common - hypothetical protein Oant_1006 7 None None None 153008680 Common - hypothetical protein Oant_1349 7 None None None 153009992 Common - two component transcriptional regulator, winged helix family Oant_2666 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153008700 Common - hypothetical protein Oant_1369 32 COG0400 COG0400, Predicted esterase General function prediction only 153007364 Common - NADH pyrophosphatase-like protein Oant_0019 105 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 153009619 Common - phage late control D family protein Oant_2289 35 COG3500 COG3500, Phage protein D General function prediction only 153009159 Common - ABC transporter related Oant_1829 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 153007613 Common - transcriptional regulator, DeoR family Oant_0268 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 153009803 Common - FAD dependent oxidoreductase Oant_2476 98 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153008281 Common - ribosomal protein L19 Oant_0946 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 153008040 Common - hypothetical protein Oant_0702 3 None None None 153007458 Common - hypothetical protein Oant_0113 3 None None None 153009538 Common - RNA chaperone Hfq Oant_2208 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 153008974 Common - two component transcriptional regulator, winged helix family Oant_1644 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153007524 Common - protein of unknown function UPF0126 Oant_0179 132 COG2860 COG2860, Predicted membrane protein Function unknown 153009570 Common - membrane protein involved in aromatic hydrocarbon degradation Oant_2240 47 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 153008796 Common - ABC transporter related Oant_1465 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153008038 Common - hypothetical protein Oant_0700 2 None None None 153008127 Common - oxidoreductase domain protein Oant_0791 167 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153009762 Common - efflux transporter, RND family, MFP subunit Oant_2434 147 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 153008782 Common - efflux transporter, RND family, MFP subunit Oant_1451 166 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 153009822 Common - ribosomal protein L13 Oant_2495 238 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 153008902 Common - uncharacterised conserved protein UCP033924 Oant_1572 22 COG5400 COG5400, Uncharacterized protein conserved in bacteria Function unknown 153009197 Common - transcriptional regulator, LysR family Oant_1867 191 COG0583 LysR, Transcriptional regulator Transcription 153009933 Common - dimethyladenosine transferase Oant_2606 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 153010073 Common - class II aldolase/adducin family protein Oant_2749 38 COG3347 COG3347, Uncharacterized conserved protein Function unknown 153009454 Common - multi-sensor hybrid histidine kinase Oant_2124 224 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153009670 Common - seryl-tRNA synthetase Oant_2342 243 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 153009733 Common - prolyl-tRNA synthetase Oant_2405 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153008860 Common - protein of unknown function DUF982 Oant_1530 3 None None None 153008450 Common - hypothetical protein Oant_1116 10 None None None 153009980 Common - hypothetical protein Oant_2654 12 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 153009283 Common - translation elongation factor G Oant_1953 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 153007828 Common - hypothetical protein Oant_0483 10 None None None 153009667 Common - peptidase M23B Oant_2339 190 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 153008954 Common - Cytochrome b/b6 domain protein Oant_1624 149 COG1290 QcrB, Cytochrome b subunit of the bc complex Energy production and conversion 153008076 Common - Beta-ketoacyl synthase Oant_0740 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153008162 Common - HPr kinase Oant_0826 73 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 153008605 Common - hypothetical protein Oant_1274 52 COG1238 COG1238, Predicted membrane protein Function unknown 153008837 Common - phage terminase GpA Oant_1506 37 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 153008239 Common - SirA family protein Oant_0904 90 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 153009596 Common - penicillin-binding protein, 1A family Oant_2266 202 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 153008093 Common - PhoH family protein Oant_0757 198 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 153009789 Common - FAD linked oxidase domain protein Oant_2462 199 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 153008492 Pathogen - hypothetical protein Oant_1160 2 None None None 153007430 Common - methionine aminopeptidase, type I Oant_0085 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 153008293 Common - acyl-CoA thioesterase II Oant_0958 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 153009719 Common - glutaredoxin-like protein Oant_2391 127 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 153008804 Common - glycoside hydrolase family 2 immunoglobulin domain protein beta-sandwich Oant_1473 39 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 153008471 Common - RNA polymerase, sigma 32 subunit, RpoH Oant_1137 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 153008915 Common - ABC transporter related Oant_1585 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 153008424 Common - peptidase M48 Ste24p Oant_1090 191 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 153008687 Common - protein of unknown function DUF817 Oant_1356 24 COG3739 COG3739, Uncharacterized integral membrane protein Function unknown 153007553 Common - HNH endonuclease Oant_0208 11 None None None 153007649 Common - Sarcosine oxidase gamma subunit Oant_0304 19 COG4583 COG4583, Sarcosine oxidase gamma subunit Amino acid transport and metabolism 153008288 Common - succinate dehydrogenase, flavoprotein subunit Oant_0953 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 153008383 Common - hypothetical protein Oant_1049 2 None None None 153007429 Common - hypothetical protein Oant_0084 22 None None None 153009516 Common - phosphonate ABC transporter, periplasmic phosphonate-binding protein Oant_2186 96 COG3221 PhnD, ABC-type phosphate/phosphonate transport system, periplasmic component Inorganic ion transport and metabolism 153008480 Common - aldo/keto reductase Oant_1146 203 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 153009503 Common - acriflavin resistance protein Oant_2173 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 153009565 Common - extracellular solute-binding protein family 3 Oant_2235 180 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153008530 Common - transcriptional regulator, GntR family Oant_1199 132 COG1802 GntR, Transcriptional regulators Transcription 153008478 Pathogen - 17 kDa surface antigen Oant_1144 2 None None None 153009290 Common - ribosomal protein S19 Oant_1960 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 153007729 Common - hypothetical protein Oant_0384 3 None None None 153008417 Common - protein of unknown function DUF477 Oant_1083 54 COG3762 COG3762, Predicted membrane protein Function unknown 153008862 Common - hypothetical protein Oant_1532 27 COG3514 COG3514, Uncharacterized protein conserved in bacteria Function unknown 153009341 Pathogen - hypothetical protein Oant_2011 2 None None None 153007770 Common - protein of unknown function DUF900 hydrolase family protein Oant_0425 24 COG4782 COG4782, Uncharacterized protein conserved in bacteria Function unknown 153009310 Common - DNA-directed RNA polymerase, alpha subunit Oant_1980 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 153008209 Common - Enoyl-CoA hydratase/isomerase Oant_0873 182 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 153008645 Common - SlyX family protein Oant_1314 16 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 153007541 Common - BA14K family protein Oant_0196 6 None None None 153007748 Common - MATE efflux family protein Oant_0403 103 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 153008017 Common - P-type DNA transfer protein VirB5 Oant_0678 22 None None None 153008736 Common - aminotransferase class-III Oant_1405 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 153008629 Common - Glutathione S-transferase domain protein Oant_1298 77 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153007724 Common - glycosyl transferase family 2 Oant_0379 138 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153009061 Common - heat shock protein DnaJ domain protein Oant_1731 58 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 153007704 Common - dihydrodipicolinate synthetase Oant_0359 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 153008071 Common - protein of unknown function DUF1058 Oant_0735 45 COG3807 COG3807, Uncharacterized protein conserved in bacteria Function unknown 153008130 Common - aldo/keto reductase Oant_0794 203 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 153009858 Common - Peptidoglycan-binding domain 1 protein Oant_2531 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 153008299 Common - cyclic nucleotide-binding protein Oant_0964 72 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 153008541 Common - protein of unknown function DUF1465 Oant_1210 18 COG5317 COG5317, Uncharacterized protein conserved in bacteria Function unknown 153010016 Common - transcriptional regulator, MucR family Oant_2690 33 COG4957 COG4957, Predicted transcriptional regulator Transcription 153008508 Pathogen - hypothetical protein Oant_1176 1 None None None 153009384 Common - CTP synthase Oant_2054 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 153008018 Common - hypothetical protein Oant_0679 5 None None None 153009922 Common - DinB family protein Oant_2595 37 COG2318 DinB, Uncharacterized protein conserved in bacteria Function unknown 153008519 Common - protein of unknown function DUF1089 Oant_1188 17 COG3554 COG3554, Uncharacterized protein conserved in bacteria Function unknown 153009485 Common - Serine-type D-Ala-D-Ala carboxypeptidase Oant_2155 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 153008945 Common - GCN5-related N-acetyltransferase Oant_1615 98 COG3153 COG3153, Predicted acetyltransferase General function prediction only 153009473 Common - GCN5-related N-acetyltransferase Oant_2143 31 COG0456 RimI, Acetyltransferases General function prediction only 153007973 Common - peptidase T2 asparaginase 2 Oant_0630 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 153007643 Common - binding-protein-dependent transport systems inner membrane component Oant_0298 126 COG1174 OpuBB, ABC-type proline/glycine betaine transport systems, permease component Amino acid transport and metabolism 153009730 Common - DNA polymerase III, alpha subunit Oant_2402 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 153009145 Common - putative transcriptional regulator, GntR family Oant_1815 223 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 153007821 Common - methylated-DNA--protein-cysteine methyltransferase Oant_0476 211 COG2169 Ada, Adenosine deaminase Nucleotide transport and metabolism 153008068 Common - NLP/P60 protein Oant_0732 70 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 153009006 Common - putative cold-shock DNA-binding domain protein Oant_1676 179 COG1278 CspC, Cold shock proteins Transcription 153009396 Common - cyclase/dehydrase Oant_2066 101 COG2867 COG2867, Oligoketide cyclase/lipid transport protein Lipid metabolism 153008993 Common - cation transporter Oant_1663 139 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 153007956 Common - protein of unknown function DUF1159 Oant_0611 20 COG5389 COG5389, Uncharacterized protein conserved in bacteria Function unknown 153009178 Common - transcriptional regulator, XRE family Oant_1848 40 COG1476 COG1476, Predicted transcriptional regulators Transcription 153008500 Common - phosphoribosylaminoimidazole carboxylase, ATPase subunit Oant_1168 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 153008692 Common - 60 kDa inner membrane insertion protein Oant_1361 215 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 153008739 Common - major facilitator superfamily MFS_1 Oant_1408 218 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 153009349 Common - Serine-type D-Ala-D-Ala carboxypeptidase Oant_2019 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 153009272 Common - NusG antitermination factor Oant_1942 215 COG0250 NusG, Transcription antiterminator Transcription 153009119 Common - Transposase and inactivated derivatives-like protein Oant_1789 47 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 153007597 Common - hypothetical protein Oant_0252 4 None None None 153009069 Common - UDP-N-acetylmuramyl-tripeptide synthetase Oant_1739 211 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 153007669 Common - protein tyrosine phosphatase Oant_0324 61 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 153009372 Common - citrate synthase I Oant_2042 194 COG0372 GltA, Citrate synthase Energy production and conversion 153008336 Common - Lysine exporter protein (LYSE/YGGA) Oant_1001 123 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 153008178 Common - protein of unknown function DUF1402 Oant_0842 6 None None None 153009714 Common - conserved hypothetical lipoprotein Oant_2386 6 None None None 153007446 Common - GCN5-related N-acetyltransferase Oant_0101 125 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 153009584 Common - FeS assembly ATPase SufC Oant_2254 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 153009240 Common - methionine aminopeptidase, type I Oant_1910 243 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 153007418 Common - fumarylacetoacetate (FAA) hydrolase Oant_0073 178 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 153008996 Common - extracellular solute-binding protein family 1 Oant_1666 96 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153009221 Common - cobalamin biosynthesis protein CobD Oant_1891 147 COG1270 CbiB, Cobalamin biosynthesis protein CobD/CbiB Coenzyme metabolism 153007894 Common - (Uracil-5)-methyltransferase Oant_0549 194 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 153007519 Common - heat shock protein Hsp20 Oant_0174 64 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 153008614 Common - Ankyrin Oant_1283 108 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 153007521 Common - endonuclease III Oant_0176 239 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 153009156 Common - TonB-dependent receptor Oant_1826 130 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 153010055 Common - transposase IS3/IS911 family protein Oant_2730 17 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009317 Common - alanyl-tRNA synthetase Oant_1987 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153009098 Pathogen - hypothetical protein Oant_1768 2 None None None 153008364 Common - glutaredoxin 3 Oant_1029 133 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 153008587 Common - TonB family protein Oant_1256 6 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 153009743 Common - NADH-quinone oxidoreductase, chain I Oant_2415 195 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 153009707 Common - protein of unknown function DUF1234 Oant_2379 53 COG3545 COG3545, Predicted esterase of the alpha/beta hydrolase fold General function prediction only 153009377 Common - molybdenum cofactor biosynthesis protein C Oant_2047 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 153008257 Pathogen - hypothetical protein Oant_0922 3 None None None 153009610 Common - trigger factor Oant_2280 212 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 153008145 Common - Phosphoribosylanthranilate isomerase Oant_0809 192 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 153009008 Common - ABC transporter domain protein Oant_1678 84 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 153008278 Common - 16S rRNA processing protein RimM Oant_0943 169 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 153007573 Pathogen - hypothetical protein Oant_0228 1 None None None 153009770 Common - urease, beta subunit Oant_2442 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 153007807 Common - cytochrome oxidase maturation protein, cbb3-type Oant_0462 3 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 153009549 Common - hypothetical protein Oant_2219 4 None None None 153007814 Common - cytochrome c oxidase, cbb3-type, subunit I Oant_0469 141 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 153008396 Common - carboxyl-terminal protease Oant_1062 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 153007980 Common - binding-protein-dependent transport systems inner membrane component Oant_0638 136 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 153008667 Common - NAD-dependent epimerase/dehydratase Oant_1336 112 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 153008658 Common - bifunctional deaminase-reductase domain protein Oant_1327 56 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 153008047 Common - IS66 Orf2 family protein Oant_0710 45 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153007360 Common - extracellular solute-binding protein family 5 Oant_0015 150 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 153007795 Common - Hydroxyisourate hydrolase Oant_0450 64 COG2351 COG2351, Transthyretin-like protein General function prediction only 153009252 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_1922 123 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 153009123 Common - Dihydrofolate reductase Oant_1793 145 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 153007908 Common - replicative DNA helicase Oant_0563 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 153008401 Common - transcriptional regulator, LysR family Oant_1067 105 COG0583 LysR, Transcriptional regulator Transcription 153007510 Common - integration host factor, beta subunit Oant_0165 208 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 153007977 Common - plasmid maintenance system antidote protein, XRE family Oant_0634 65 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 153008969 Common - prolipoprotein diacylglyceryl transferase Oant_1639 206 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 153007851 Common - Lysine exporter protein (LYSE/YGGA) Oant_0506 44 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 153007717 Common - Glutathione S-transferase domain protein Oant_0372 70 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 153008528 Common - protein of unknown function DUF1284 Oant_1197 16 COG3543 COG3543, Uncharacterized conserved protein Function unknown 153008213 Common - Choline dehydrogenase Oant_0877 93 COG2303 BetA, Choline dehydrogenase and related flavoproteins Amino acid transport and metabolism 153008868 Pathogen - hypothetical protein Oant_1538 1 None None None 153008716 Common - PntAB, NAD(P) transhydrogenase, alpha2 subunit Oant_1385 117 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 153007373 Common - hypothetical protein Oant_0028 7 None None None 153008195 Common - glucose inhibited division protein A Oant_0859 193 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 153008777 Common - putative transcriptional regulator, AsnC family Oant_1446 156 COG1522 Lrp, Transcriptional regulators Transcription 153009490 Common - Patatin Oant_2160 123 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 153007919 Common - aminodeoxychorismate lyase Oant_0574 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 153007650 Common - L-carnitine dehydratase/bile acid-inducible protein F Oant_0305 116 COG1804 CaiB, Predicted acyl-CoA transferases/carnitine dehydratase Energy production and conversion 153008786 Common - Glutamine--fructose-6-phosphate transaminase (isomerizing) Oant_1455 232 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 153008709 Common - peptidase C26 Oant_1378 114 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 153009055 Common - lytic murein transglycosylase Oant_1725 99 COG2951 MltB, Membrane-bound lytic murein transglycosylase B Cell envelope biogenesis, outer membrane 153009914 Common - porin Oant_2587 17 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 153009292 Common - ribosomal protein S3 Oant_1962 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 153009752 Common - NADH-ubiquinone/plastoquinone oxidoreductase chain 3 Oant_2424 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 153007929 Pathogen - hypothetical protein Oant_0584 2 None None None 153010051 Common - transposase IS66 Oant_2726 57 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153009166 Common - sulfatase Oant_1836 85 COG3119 AslA, Arylsulfatase A and related enzymes Inorganic ion transport and metabolism 153009945 Common - transcriptional regulator, AraC family Oant_2618 119 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 153008351 Common - UspA domain protein Oant_1016 149 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 153008549 Common - Tol-Pal system beta propeller repeat TolB Oant_1218 160 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 153009809 Common - argininosuccinate lyase Oant_2482 232 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 153008036 Common - glycosyl transferase family 4 Oant_0698 42 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 153008636 Common - phage-related hypothetical protein Oant_1305 14 None None None 153009452 Common - transcriptional regulator, TraR/DksA family Oant_2122 160 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 153007543 Common - Autoinducer-binding domain protein Oant_0198 44 COG2771 CsgD, DNA-binding HTH domain-containing proteins Transcription 153009924 Pathogen - hypothetical protein Oant_2597 1 None None None 153008489 Common - metallophosphoesterase Oant_1156 34 COG1409 Icc, Predicted phosphohydrolases General function prediction only 153008932 Common - NUDIX hydrolase Oant_1602 52 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 153009710 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Oant_2382 158 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 153007800 Common - protein of unknown function DUF989 Oant_0455 37 COG3748 COG3748, Predicted membrane protein Function unknown 153009047 Common - lysophospholipase L2 Oant_1717 89 COG2267 PldB, Lysophospholipase Lipid metabolism 153009336 Pathogen - hypothetical protein Oant_2006 2 None None None 153009467 Common - MscS Mechanosensitive ion channel Oant_2137 209 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 153009182 Common - Integral membrane protein TerC Oant_1852 215 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 153009109 Common - phage terminase GpA Oant_1779 38 COG5525 COG5525, Bacteriophage tail assembly protein General function prediction only 153007694 Common - transcriptional regulator, TetR family Oant_0349 101 COG1309 AcrR, Transcriptional regulator Transcription 153007537 Common - uncharacterised conserved protein UCP030820 Oant_0192 54 COG3749 COG3749, Uncharacterized protein conserved in bacteria Function unknown 153009893 Pathogen - hypothetical protein Oant_2566 1 None None None 153007371 Common - transcriptional regulator, LysR family Oant_0026 191 COG0583 LysR, Transcriptional regulator Transcription 153008284 Pathogen - hypothetical protein Oant_0949 1 None None None 153009353 Common - branched-chain amino acid transport Oant_2023 8 None None None 153009779 Common - hypothetical protein Oant_2451 10 COG3111 COG3111, Uncharacterized conserved protein Function unknown 153009953 Common - GTP-binding protein Era Oant_2626 216 COG1159 Era, GTPase General function prediction only 153007847 Common - H+transporting two-sector ATPase B/B' subunit Oant_0502 34 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 153009836 Common - Undecaprenyl-phosphate galactose phosphotransferase Oant_2509 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 153008334 Common - argininosuccinate lyase Oant_0999 235 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 153007786 Common - Invasion associated locus B family protein Oant_0441 20 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 153008300 Common - two component transcriptional regulator, winged helix family Oant_0965 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153007393 Common - ubiquinol oxidase, subunit II Oant_0048 142 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 153007380 Common - protein of unknown function DUF6 transmembrane Oant_0035 110 None None None 153008884 Pathogen - hypothetical protein Oant_1554 1 None None None 153009606 Common - hypothetical protein Oant_2276 28 COG4765 COG4765, Uncharacterized protein conserved in bacteria Function unknown 153009780 Common - Lipopolysaccharide biosynthesis protein-like protein Oant_2452 12 COG3754 RgpF, Lipopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 153007935 Common - homoserine kinase Oant_0590 67 COG2334 COG2334, Putative homoserine kinase type II (protein kinase fold) General function prediction only 153009226 Common - precorrin-3B C17-methyltransferase Oant_1896 117 COG1010 CobJ, Precorrin-3B methylase Coenzyme metabolism 153007624 Common - transcriptional activator, TenA family Oant_0279 74 COG0819 TenA, Putative transcription activator Transcription 153008113 Common - GCN5-related N-acetyltransferase Oant_0777 118 COG0456 RimI, Acetyltransferases General function prediction only 153007761 Common - hypothetical protein Oant_0416 7 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 153007758 Common - hypothetical protein Oant_0413 10 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153009307 Common - adenylate kinase Oant_1977 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 153008879 Pathogen - hypothetical protein Oant_1549 1 None None None 153009397 Common - short-chain dehydrogenase/reductase SDR Oant_2067 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153007896 Common - conserved hypothetical protein 730 Oant_0551 147 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 153010041 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I Oant_2716 240 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 153007398 Common - surface antigen (D15) Oant_0053 131 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 153007885 Common - 3,4-dihydroxy-2-butanone 4-phosphate synthase Oant_0540 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 153007712 Common - protein of unknown function DUF6 transmembrane Oant_0367 56 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 153009870 Common - Ppx/GppA phosphatase Oant_2543 168 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 153007962 Common - protein of unknown function DUF132 Oant_0618 11 None None None 153009641 Common - hypothetical protein Oant_2313 14 None None None 153007671 Common - Histidinol dehydrogenase Oant_0326 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 153009434 Common - metallophosphoesterase Oant_2104 70 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 153008295 Common - cell divisionFtsK/SpoIIIE Oant_0960 197 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 153009601 Common - DSBA oxidoreductase Oant_2271 98 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 153009161 Common - periplasmic binding protein/LacI transcriptional regulator Oant_1831 88 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 153008870 Pathogen - hypothetical protein Oant_1540 2 None None None 153008893 Common - Resolvase domain protein Oant_1563 78 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 153008358 Common - arginine biosynthesis bifunctional protein ArgJ Oant_1023 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 153008720 Common - MaoC domain protein dehydratase Oant_1389 80 COG2030 MaoC, Acyl dehydratase Lipid metabolism 153009739 Common - proton-translocating NADH-quinone oxidoreductase, chain M Oant_2411 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 153007607 Common - hypothetical protein Oant_0262 2 None None None 153008556 Common - porin opacity type Oant_1225 27 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 153007841 Common - protein of unknown function DUF1311 Oant_0496 30 COG3755 COG3755, Uncharacterized protein conserved in bacteria Function unknown 153009092 Common - transferase hexapeptide repeat containing protein Oant_1762 172 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 153008825 Common - hypothetical protein Oant_1494 4 None None None 153008083 Common - translation initiation factor IF-2 Oant_0747 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 153009114 Common - phage portal protein, lambda family Oant_1784 38 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 153008169 Common - phosphoribosyl-ATP pyrophosphohydrolase Oant_0833 145 COG0140 HisI, Phosphoribosyl-ATP pyrophosphohydrolase Amino acid transport and metabolism 153007638 Common - periplasmic binding protein/LacI transcriptional regulator Oant_0293 126 COG1609 PurR, Transcriptional regulators Transcription 153007878 Common - hypothetical protein Oant_0533 9 None None None 153009682 Common - protein of unknown function DUF533 Oant_2354 38 COG2979 COG2979, Uncharacterized protein conserved in bacteria Function unknown 153009482 Common - nitroreductase Oant_2152 80 COG0778 NfnB, Nitroreductase Energy production and conversion 153009523 Common - phosphonate metabolism PhnJ Oant_2193 45 COG3627 PhnJ, Uncharacterized enzyme of phosphonate metabolism Inorganic ion transport and metabolism 153008759 Common - ABC transporter related Oant_1428 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 153009616 Pathogen - hypothetical protein Oant_2286 1 None None None 153007773 Common - hypothetical protein Oant_0428 33 COG4111 COG4111, Uncharacterized conserved protein General function prediction only 153007858 Common - hypothetical protein Oant_0513 6 None None None 153009815 Common - hypothetical protein Oant_2488 3 None None None 153007500 Common - tryptophanyl-tRNA synthetase Oant_0155 230 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 153009407 Common - dTMP kinase Oant_2077 230 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 153010064 Common - ABC-2 type transporter Oant_2740 109 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 153007995 Common - Pyridoxal-5'-phosphate-dependent protein beta subunit Oant_0655 206 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 153008547 Common - Biopolymer transport TolR Oant_1216 138 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 153009998 Common - outer membrane lipoprotein-related protein Oant_2672 19 COG4520 LipA, Surface antigen Cell envelope biogenesis, outer membrane 153008740 Common - Asp/Glu racemase Oant_1409 38 COG4126 COG4126, Hydantoin racemase Amino acid transport and metabolism 153009885 Common - phosphoesterase PA-phosphatase related Oant_2558 66 None None None 153007387 Common - Extracellular ligand-binding receptor Oant_0042 149 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 153009380 Common - rotamase family protein Oant_2050 118 None None None 153008743 Common - D-aminopeptidase domain C Oant_1412 103 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 153007861 Common - hypothetical protein Oant_0516 4 None None None 153008190 Common - uroporphyrinogen decarboxylase Oant_0854 177 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 153008624 Common - Amidase Oant_1293 221 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 153007824 Common - hypothetical protein Oant_0479 8 COG4129 COG4129, Predicted membrane protein Function unknown 153009867 Common - hypothetical protein Oant_2540 6 None None None 153008421 Common - phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase Oant_1087 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 153009816 Pathogen - Flp/Fap pilin component Oant_2489 1 COG3847 Flp, Flp pilus assembly protein, pilin Flp Intracellular trafficking and secretion 153009855 Common - riboflavin biosynthesis protein RibD Oant_2528 229 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 153010021 Common - cytochrome c class II Oant_2695 28 COG3909 COG3909, Cytochrome c556 Energy production and conversion 153007918 Common - Beta-ketoacyl synthase Oant_0573 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153010013 Common - conserved hypothetical cytosolic protein Oant_2687 20 None None None 153007402 Pathogen - conserved hypothetical cytosolic protein (cysteine-rich) Oant_0057 2 None None None 153008261 Common - MiaB-like tRNA modifying enzyme Oant_0926 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 153009265 Common - type IV pilus assembly PilZ Oant_1935 12 None None None 153009877 Common - Activator of Hsp90 ATPase 1 family protein Oant_2550 12 COG3832 COG3832, Uncharacterized conserved protein Function unknown 153009324 Common - intracellular protease, PfpI family Oant_1994 139 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 153007353 Common - protein of unknown function DUF521 Oant_0008 39 COG1679 COG1679, Uncharacterized conserved protein Function unknown 153007614 Common - FAD dependent oxidoreductase Oant_0269 151 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 153008305 Common - hypothetical protein Oant_0970 75 COG3897 COG3897, Predicted methyltransferase General function prediction only 153007485 Common - cytochrome P450 Oant_0140 87 COG2124 CypX, Cytochrome P450 Secondary metabolites biosynthesis, transport, and catabolism 153007631 Common - diguanylate cyclase/phosphodiesterase with PAS/PAC and GAF sensor(s) Oant_0286 191 COG5001 COG5001, Predicted signal transduction protein containing a membrane domain, an EAL and a GGDEF domain Signal transduction mechanisms 153008487 Pathogen - hypothetical protein Oant_1154 1 None None None 153008973 Common - integral membrane sensor signal transduction histidine kinase Oant_1643 212 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153009420 Pathogen - hypothetical protein Oant_2090 2 None None None 153009650 Pathogen - hypothetical protein Oant_2322 1 None None None 153009965 Common - protein of unknown function DUF88 Oant_2638 65 COG1432 COG1432, Uncharacterized conserved protein Function unknown 153007348 Common - chromosomal replication initiator protein DnaA Oant_0003 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 153009860 Common - protein of unknown function DUF411 Oant_2533 64 COG3019 COG3019, Predicted metal-binding protein General function prediction only 153007660 Common - oxidoreductase domain protein Oant_0315 90 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153008603 Common - HNH endonuclease Oant_1272 97 COG1403 McrA, Restriction endonuclease Defense mechanisms 153008682 Common - transglutaminase family protein cysteine peptidase BTLCP Oant_1351 31 COG3672 COG3672, Predicted periplasmic protein Function unknown 153009994 Common - cytochrome C biogenesis protein Oant_2668 89 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 153008185 Common - DNA polymerase III, epsilon subunit Oant_0849 195 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 153009478 Common - Bile acid:sodium symporter Oant_2148 55 COG0385 COG0385, Predicted Na+-dependent transporter General function prediction only 153009487 Common - nitrogen-fixing NifU domain protein Oant_2157 97 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 153009536 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Oant_2206 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 153008202 Common - inner-membrane translocator Oant_0866 68 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 153008502 Common - protein of unknown function DUF465 Oant_1170 13 COG5481 COG5481, Uncharacterized conserved small protein containing a coiled-coil domain Function unknown 153010038 Common - alpha,alpha-trehalose-phosphate synthase (UDP-forming) Oant_2713 96 COG0380 OtsA, Trehalose-6-phosphate synthase Carbohydrate transport and metabolism 153009281 Common - ribosomal protein S12 Oant_1951 239 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 153009813 Common - ROK family protein Oant_2486 176 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 153008670 Common - putative undecaprenol kinase Oant_1339 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 153008551 Common - Peptidoglycan-associated lipoprotein Oant_1220 155 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 153008105 Common - phosphate ABC transporter, inner membrane subunit PstA Oant_0769 221 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 153007852 Common - Ribonuclease H Oant_0507 208 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 153009244 Common - Peptidase M15A Oant_1914 55 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 153007523 Common - PfkB domain protein Oant_0178 198 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 153009676 Common - Beta-N-acetylhexosaminidase Oant_2348 167 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 153009689 Common - cobalamin 5'-phosphate synthase Oant_2361 111 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 153008765 Common - N-formylglutamate amidohydrolase Oant_1434 57 COG3741 HutG, N-formylglutamate amidohydrolase Amino acid transport and metabolism 153008784 Common - acriflavin resistance protein Oant_1453 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 153009656 Common - hypothetical protein Oant_2328 7 None None None 153008976 Common - branched-chain amino acid aminotransferase Oant_1646 216 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 153007863 Common - hypothetical protein Oant_0518 22 None None None 153009235 Common - binding-protein-dependent transport systems inner membrane component Oant_1905 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153008850 Common - hypothetical protein Oant_1520 8 None None None 153008452 Common - Extracellular ligand-binding receptor Oant_1118 139 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 153009302 Common - ribosomal protein L18 Oant_1972 214 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 153008490 Pathogen - hypothetical protein Oant_1158 4 None None None 153007584 Common - peptidase U35 phage prohead HK97 Oant_0239 18 None None None 153008180 Common - Smr protein/MutS2 Oant_0844 85 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 153009379 Common - anthranilate phosphoribosyltransferase Oant_2049 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 153007930 Common - cytochrome c oxidase assembly protein CtaG/Cox11 Oant_0585 68 COG3175 COX11, Cytochrome oxidase assembly factor Posttranslational modification, protein turnover, chaperones 153009089 Common - ribosomal L11 methyltransferase Oant_1759 153 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 153008940 Common - protein of unknown function DUF1285 Oant_1610 44 COG3816 COG3816, Uncharacterized protein conserved in bacteria Function unknown 153007997 Common - IS66 Orf2 family protein Oant_0658 51 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 153007526 Common - heat-inducible transcription repressor HrcA Oant_0181 148 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 153008835 Common - peptidase U35 phage prohead HK97 Oant_1504 22 COG3740 COG3740, Phage head maturation protease General function prediction only 153009717 Common - phosphoribosylformylglycinamidine synthase II Oant_2389 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 153009017 Pathogen - hypothetical protein Oant_1687 1 None None None 153009143 Common - ketol-acid reductoisomerase Oant_1813 214 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 153008917 Common - ABC transporter related Oant_1587 249 COG4175 ProV, ABC-type proline/glycine betaine transport system, ATPase component Amino acid transport and metabolism 153009103 Common - protein of unknown function DUF1321 Oant_1773 40 COG3814 COG3814, Uncharacterized protein conserved in bacteria Function unknown 153009844 Pathogen - hypothetical protein Oant_2517 1 None None None 153009322 Common - isocitrate dehydrogenase, NADP-dependent Oant_1992 65 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 153009582 Common - cysteine desulfurase, SufS subfamily Oant_2252 240 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 153007559 Common - hypothetical protein Oant_0214 11 None None None 153009475 Pathogen - hypothetical protein Oant_2145 1 None None None 153009563 Common - molybdopterin-guanine dinucleotide biosynthesis protein A Oant_2233 71 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 153007356 Common - ABC transporter related Oant_0011 249 COG4172 COG4172, ABC-type uncharacterized transport system, duplicated ATPase component General function prediction only 153008466 Common - RNA-binding S4 domain protein Oant_1132 105 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 153008842 Pathogen - hypothetical protein Oant_1512 2 None None None 153009909 Common - hypothetical protein Oant_2582 10 COG5511 COG5511, Bacteriophage capsid protein General function prediction only 153008444 Common - D-amino-acid dehydrogenase Oant_1110 124 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 153008647 Common - uracil phosphoribosyltransferase Oant_1316 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 153008414 Common - GCN5-related N-acetyltransferase Oant_1080 69 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 153009032 Common - hypothetical protein Oant_1702 19 None None None 153008433 Common - putative transaldolase Oant_1099 154 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 153007750 Common - protein of unknown function DUF952 Oant_0405 46 COG3502 COG3502, Uncharacterized protein conserved in bacteria Function unknown 153009936 Common - 2-isopropylmalate synthase/homocitrate synthase family protein Oant_2609 212 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 153008811 Common - Glyoxalase/bleomycin resistance protein/dioxygenase Oant_1480 18 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 153009625 Common - phage tail sheath protein Oant_2295 34 COG3497 COG3497, Phage tail sheath protein FI General function prediction only 153007592 Common - phage protein, HK97 gp10 family Oant_0247 6 None None None 153008745 Common - GntR domain protein Oant_1414 91 COG2186 FadR, Transcriptional regulators Transcription 153009415 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Oant_2085 164 COG0546 Gph, Predicted phosphatases General function prediction only 153008510 Common - Invasion associated locus B family protein Oant_1179 12 COG5342 COG5342, Invasion protein B, involved in pathogenesis General function prediction only 153008677 Common - tRNA pseudouridine synthase A Oant_1346 235 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 153007987 Common - YecA family protein Oant_0645 11 COG3318 COG3318, Predicted metal-binding protein related to the C-terminal domain of SecA General function prediction only 153008581 Pathogen - hypothetical protein Oant_1250 2 None None None 153008689 Common - acetylglutamate kinase Oant_1358 219 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 153008343 Common - Radical SAM domain protein Oant_1008 117 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 153008768 Common - formiminoglutamate deiminase Oant_1437 107 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 153008053 Common - hypothetical protein Oant_0717 16 COG4961 TadG, Flp pilus assembly protein TadG Intracellular trafficking and secretion 153007645 Common - Glu/Leu/Phe/Val dehydrogenase Oant_0300 180 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 153007921 Common - Guanylate kinase Oant_0576 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 153008575 Common - signal transduction histidine kinase Oant_1244 38 COG3920 COG3920, Signal transduction histidine kinase Signal transduction mechanisms 153009270 Common - translation elongation factor Tu Oant_1940 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 153007967 Common - transcriptional regulator, RpiR family Oant_0624 69 COG1737 RpiR, Transcriptional regulators Transcription 153009884 Common - cationic amino acid ABC transporter, periplasmic binding protein Oant_2557 124 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 153009577 Common - FeS assembly scaffold SufA Oant_2247 164 COG0316 IscA, Uncharacterized conserved protein Function unknown 153009217 Common - cobalamin biosynthesis protein CbiD Oant_1887 95 COG1903 CbiD, Cobalamin biosynthesis protein CbiD Coenzyme metabolism 153008153 Common - Double-strand break repair helicase AddA Oant_0817 226 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 153008372 Common - modification methylase, HemK family Oant_1037 221 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 153007678 Common - HupE/UreJ protein Oant_0333 43 COG2370 HupE, Hydrogenase/urease accessory protein Posttranslational modification, protein turnover, chaperones 153007379 Common - acyltransferase 3 Oant_0034 24 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 153010076 Common - glycosyl transferase family 2 Oant_2752 175 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 153008318 Pathogen - hypothetical protein Oant_0983 1 None None None 153007477 Common - porin Oant_0132 27 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 153007564 Common - putative phage repressor Oant_0219 39 COG2932 COG2932, Predicted transcriptional regulator Transcription 153009238 Common - hypothetical protein Oant_1908 20 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 153007736 Common - glycosyl transferase group 1 Oant_0391 165 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153008707 Common - Alanine racemase Oant_1376 128 COG1609 PurR, Transcriptional regulators Transcription 153009386 Common - Phosphopyruvate hydratase Oant_2056 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 153008991 Common - glycosyl transferase group 1 Oant_1661 199 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 153008610 Common - polysaccharide deacetylase Oant_1279 43 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 153009242 Pathogen - hypothetical protein Oant_1912 1 None None None 153009366 Common - surface antigen (D15) Oant_2036 159 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 153009586 Pathogen - hypothetical protein Oant_2256 1 None None None 153007498 Common - Scaffold protein Nfu/NifU Oant_0153 93 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 153007709 Common - ABC transporter related Oant_0364 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 153008024 Common - P-type DNA transfer ATPase VirB11 Oant_0685 178 COG0630 VirB11, Type IV secretory pathway, VirB11 components, and related ATPases involved in archaeal flagella biosynthesis Cell motility and secretion / Intracellular trafficking and secretion 153008947 Common - hypothetical protein Oant_1617 9 None None None 153009112 Common - DNA-binding protein Oant_1782 8 None None None 153008034 Common - Hydroxyisourate hydrolase Oant_0695 63 COG2351 COG2351, Transthyretin-like protein General function prediction only 153008964 Common - ribose-phosphate pyrophosphokinase Oant_1634 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 153008959 Common - GTP-binding protein YchF Oant_1629 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 153009699 Common - phosphopantetheine-binding Oant_2371 91 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 153008015 Common - type IV secretory pathway VirB3 family protein Oant_0676 12 COG3702 VirB3, Type IV secretory pathway, VirB3 components Intracellular trafficking and secretion 153007722 Pathogen - hypothetical protein Oant_0377 2 None None None 153009297 Common - ribosomal protein L24 Oant_1967 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 153009347 Common - uncharacterised conserved protein UCP032025 Oant_2017 31 COG5458 COG5458, Uncharacterized conserved protein Function unknown 153008612 Common - major facilitator superfamily MFS_1 Oant_1281 74 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 153008994 Common - thioredoxin reductase Oant_1664 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 153008539 Common - thiamine monophosphate synthase Oant_1208 64 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 153009071 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Oant_1741 217 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 153008823 Pathogen - hypothetical protein Oant_1492 1 None None None 153008513 Common - short-chain dehydrogenase/reductase SDR Oant_1182 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 153009088 Common - peptidase M24 Oant_1758 237 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 153009795 Pathogen - hypothetical protein Oant_2468 1 None None None 153007816 Common - two component transcriptional regulator, winged helix family Oant_0471 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 153007535 Common - Sulfite reductase (ferredoxin) Oant_0190 165 COG0155 CysI, Sulfite reductase, beta subunit (hemoprotein) Inorganic ion transport and metabolism 153009000 Common - metallophosphoesterase Oant_1670 49 COG1409 Icc, Predicted phosphohydrolases General function prediction only 153008366 Common - protein of unknown function DUF1178 Oant_1031 47 COG5319 COG5319, Uncharacterized protein conserved in bacteria Function unknown 153009575 Common - Heavy metal transport/detoxification protein Oant_2245 13 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 153009319 Common - NIPSNAP family containing protein Oant_1989 17 None None None 153009504 Common - efflux transporter, RND family, MFP subunit Oant_2174 165 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 153008171 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Oant_0835 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 153008756 Common - ABC transporter related Oant_1425 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 153007439 Common - transcriptional coactivator/pterin dehydratase Oant_0094 84 COG2154 COG2154, Pterin-4a-carbinolamine dehydratase Coenzyme metabolism 153007741 Common - Hsp33 protein Oant_0396 128 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 153009135 Common - acetolactate synthase, small subunit Oant_1805 188 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 153007448 Common - protein of unknown function DUF1223 Oant_0103 33 COG5429 COG5429, Uncharacterized secreted protein Function unknown 153010057 Common - glycosyltransferase-like protein Oant_2733 7 COG5325 COG5325, t-SNARE complex subunit, syntaxin Intracellular trafficking and secretion 153009184 Common - sulfate ABC transporter, periplasmic sulfate-binding protein Oant_1854 88 COG4150 CysP, ABC-type sulfate transport system, periplasmic component Inorganic ion transport and metabolism 153007440 Common - protein tyrosine phosphatase Oant_0095 141 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 153008251 Common - short-chain dehydrogenase/reductase SDR Oant_0916 238 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 153007420 Pathogen - hypothetical protein Oant_0075 2 None None None 153009741 Common - NADH-ubiquinone oxidoreductase chain 4L Oant_2413 132 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 153007411 Common - transcriptional regulator, AraC family Oant_0066 65 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 153008078 Common - methyltransferase small Oant_0742 66 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 153009223 Common - flavin reductase domain protein FMN-binding Oant_1893 110 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 153008640 Pathogen - hypothetical protein Oant_1309 1 None None None 153008143 Common - protein of unknown function DUF45 Oant_0807 151 COG1451 COG1451, Predicted metal-dependent hydrolase General function prediction only 153008576 Pathogen - protein of unknown function DUF1328 Oant_1245 1 None None None 153009150 Common - pyridoxamine 5'-phosphate oxidase-related FMN-binding Oant_1820 8 COG3467 COG3467, Predicted flavin-nucleotide-binding protein General function prediction only 153009630 Common - GPW/gp25 family protein Oant_2300 33 COG3628 COG3628, Phage baseplate assembly protein W General function prediction only 153009690 Common - protein of unknown function DUF1289 Oant_2362 47 COG3313 COG3313, Predicted Fe-S protein General function prediction only 153007953 Common - glycosyl transferase family 25 Oant_0608 27 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 153008694 Common - ribosomal protein L34 Oant_1363 190 None None None 153009705 Common - adenylosuccinate lyase Oant_2377 241 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 153008061 Common - response regulator receiver protein Oant_0725 101 COG4963 CpaE, Flp pilus assembly protein, ATPase CpaE Intracellular trafficking and secretion 153007493 Common - integral membrane sensor signal transduction histidine kinase Oant_0148 73 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 153009063 Common - Lytic transglycosylase catalytic Oant_1733 108 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 153009827 Common - N-acetyl-gamma-glutamyl-phosphate reductase Oant_2500 209 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 153008806 Common - hypothetical protein Oant_1475 16 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 153008345 Common - exsB protein Oant_1010 177 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 153007462 Common - protein of unknown function DUF930 Oant_0117 10 None None None 153009639 Common - hypothetical protein Oant_2311 4 None None None 153009518 Common - phosphonate metabolism protein/1,5-bisphosphokinase (PRPP-forming) PhnN Oant_2188 83 COG3709 COG3709, Uncharacterized component of phosphonate metabolism Inorganic ion transport and metabolism 153008286 Common - Succinate dehydrogenase cytochrome b556 subunit Oant_0951 88 COG2009 SdhC, Succinate dehydrogenase/fumarate reductase, cytochrome b subunit Energy production and conversion 153008381 Common - pseudouridine synthase Oant_1047 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 153007663 Common - 5-carboxymethyl-2-hydroxymuconate Delta-isomerase Oant_0318 180 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 153009552 Pathogen - hypothetical protein Oant_2222 1 None None None 153008003 Common - Uncharacterized protein UPF0065 Oant_0664 74 COG3181 COG3181, Uncharacterized protein conserved in bacteria Function unknown 153008984 Common - SH3 type 3 domain protein Oant_1654 16 COG4991 COG4991, Uncharacterized protein with a bacterial SH3 domain homologue Function unknown 153009449 Common - conserved hypothetical protein 1620 Oant_2119 43 COG3768 COG3768, Predicted membrane protein Function unknown 153009331 Common - methylmalonyl-CoA mutase, large subunit Oant_2001 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 153009856 Common - ATP-cone domain protein Oant_2529 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 153008207 Common - oxidoreductase domain protein Oant_0871 170 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 153007746 Common - hypothetical protein Oant_0401 12 None None None 153009751 Common - NADH-quinone oxidoreductase, B subunit Oant_2423 191 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 153010061 Common - hypothetical protein Oant_2737 2 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 153009044 Common - UDP-glucose 6-dehydrogenase Oant_1714 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 153008028 Common - Gluconate 2-dehydrogenase (acceptor) Oant_0689 64 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 153008864 Common - hypothetical protein Oant_1534 2 None None None 153008073 Common - lipoprotein, YaeC family Oant_0737 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 153007837 Common - heat shock protein, Hsp70 family Oant_0492 233 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 153009171 Common - binding-protein-dependent transport systems inner membrane component Oant_1841 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 153008925 Common - transcriptional regulator, MarR family Oant_1595 51 COG1846 MarR, Transcriptional regulators Transcription 153007551 Pathogen - hypothetical protein Oant_0206 1 None None None 153009510 Common - pantetheine-phosphate adenylyltransferase Oant_2180 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 153009024 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Oant_1694 159 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 153007971 Common - binding-protein-dependent transport systems inner membrane component Oant_0628 221 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism