Klebsiella pneumoniae subsp. pneumoniae MGH 78578 plasmid pKPN5, complete sequence NC_009651 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 152973745 Pathogen - hypothetical protein KPN_pKPN5p08174 5 None None None 152973790 Common - plasmid F resolvase-like protein KPN_pKPN5p08219 192 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 152973797 Common impA ImpA-like protein; UV protection KPN_pKPN5p08226 79 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 152973760 Common - putative adenosylmethionine-8-amino-7-oxononanoate aminotransferase KPN_pKPN5p08189 22 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 152973777 Common - transposase KPN_pKPN5p08206 48 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973758 Common - putative resolvase KPN_pKPN5p08187 71 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 152973824 Common - putative transposase KPN_pKPN5p08253 48 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973820 Common - putative permeases of the major facilitator superfamily KPN_pKPN5p08249 20 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152973814 Common - hypothetical protein KPN_pKPN5p08243 13 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 152973809 Common - hypothetical protein KPN_pKPN5p08238 5 None None None 152973733 Common - putative transposase KPN_pKPN5p08162 5 None None None 152973752 Common - putative transposase KPN_pKPN5p08181 57 COG4644 COG4644, Transposase and inactivated derivatives, TnpA family DNA replication, recombination, and repair 152973766 Common - putative transposase KPN_pKPN5p08195 48 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973799 Pathogen stbB mediator of plasmid stability KPN_pKPN5p08228 2 None None None 152973803 Pathogen - hypothetical protein KPN_pKPN5p08232 1 None None None 152973751 Common - streptomycin resistance protein B KPN_pKPN5p08180 23 COG3570 StrB, Streptomycin 6-kinase Defense mechanisms 152973769 Common - putative dihydrofolate reductase KPN_pKPN5p08198 131 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 152973743 Pathogen - hypothetical protein KPN_pKPN5p08172 5 None None None 152973756 Common - putative transposase KPN_pKPN5p08185 11 None None None 152973822 Common - putative sodium-proton antiporter NhaA KPN_pKPN5p08251 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 152973812 Common - putative transposase KPN_pKPN5p08241 63 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973779 Common - hypothetical protein KPN_pKPN5p08208 5 None None None 152973785 Pathogen - hypothetical protein KPN_pKPN5p08214 2 None None None 152973749 Common - putative resolvase KPN_pKPN5p08178 120 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 152973805 Common cmlA2 chloramphenicol acetyltransferase KPN_pKPN5p08234 20 COG4845 COG4845, Chloramphenicol O-acetyltransferase Defense mechanisms 152973741 Common - putative antirestriction protein KPN_pKPN5p08170 12 COG4734 ArdA, Antirestriction protein General function prediction only 152973787 Pathogen - hypothetical protein KPN_pKPN5p08216 2 None None None 152973811 Common - putative transposase KPN_pKPN5p08240 48 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973793 Common - hypothetical protein KPN_pKPN5p08222 8 None None None 152973764 Pathogen - hypothetical protein KPN_pKPN5p08193 1 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 152973737 Pathogen - hypothetical protein KPN_pKPN5p08166 1 None None None 152973773 Common cmlA1 chloramphenicol resistance protein KPN_pKPN5p08202 150 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152973829 Common bla putative TEM-1 beta-lactamase KPN_pKPN5p08258 58 COG2367 PenP, Beta-lactamase class A Defense mechanisms 152973795 Common paraB plasmid partition protein B KPN_pKPN5p08224 11 COG1475 Spo0J, Predicted transcriptional regulators Transcription 152973818 Common - putative sulfate permease KPN_pKPN5p08247 162 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 152973815 Common - putative transposase KPN_pKPN5p08244 18 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 152973735 Common - hypothetical protein KPN_pKPN5p08164 23 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 152973746 Common - hypothetical protein KPN_pKPN5p08175 112 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 152973747 Pathogen - hypothetical protein KPN_pKPN5p08176 1 None None None 152973806 Common - putative transposase KPN_pKPN5p08235 48 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973754 Common sul dihydropteroate synthase KPN_pKPN5p08183 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 152973780 Pathogen - hypothetical protein KPN_pKPN5p08209 1 None None None 152973775 Common - aminoglycoside adenylyltransferase KPN_pKPN5p08204 6 None None None 152973789 Pathogen - hypothetical protein KPN_pKPN5p08218 1 None None None 152973770 Common - hypothetical protein KPN_pKPN5p08199 14 None None None 152973796 Common - mutagenesis by UV and mutagens KPN_pKPN5p08225 182 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 152973816 Pathogen - putative transposase KPN_pKPN5p08245 1 None None None 152973827 Common tetD tetracycline resistance protein, efflux, class D KPN_pKPN5p08256 82 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 152973821 Common - putative CrcB-like protein KPN_pKPN5p08250 182 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 152973808 Common - hypothetical protein KPN_pKPN5p08237 7 COG5464 COG5464, Uncharacterized conserved protein Function unknown 152973750 Common str putative APH(3'') streptomycin phosphotransferase KPN_pKPN5p08179 18 COG3231 Aph, Aminoglycoside phosphotransferase Translation, ribosomal structure and biogenesis 152973801 Common - hypothetical protein KPN_pKPN5p08230 62 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 152973826 Pathogen - hypothetical protein KPN_pKPN5p08255 1 None None None 152973732 Common - putative resolvase KPN_pKPN5p08161 144 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 152973753 Common - putative transposase KPN_pKPN5p08182 76 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973776 Common - integrase KPN_pKPN5p08205 219 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 152973791 Pathogen - hypothetical protein KPN_pKPN5p08220 1 None None None 152973802 Common - putative alcohol dehydrogenase class III KPN_pKPN5p08231 148 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 152973734 Common - putative transposase KPN_pKPN5p08163 48 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973763 Common - hypothetical protein KPN_pKPN5p08192 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 152973782 Common - hypothetical protein KPN_pKPN5p08211 2 None None None 152973771 Common sul dihydropteroate synthase KPN_pKPN5p08200 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 152973825 Common tetR tetracycline resistance, repressor protein, tetR family KPN_pKPN5p08254 40 COG1309 AcrR, Transcriptional regulator Transcription 152973798 Common stbA mediator of plasmid stability KPN_pKPN5p08227 9 None None None 152973813 Common - hypothetical protein KPN_pKPN5p08242 9 None None None 152973823 Common - sugE, small multidrug resistance family KPN_pKPN5p08252 145 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 152973757 Common - hypothetical protein KPN_pKPN5p08186 4 None None None 152973739 Common - hypothetical protein KPN_pKPN5p08168 11 None None None 152973759 Common - hypothetical protein KPN_pKPN5p08188 48 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973778 Pathogen - hypothetical protein KPN_pKPN5p08207 1 None None None 152973819 Common - hypothetical protein KPN_pKPN5p08248 53 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 152973767 Common - replication initiator protein KPN_pKPN5p08196 28 COG5527 COG5527, Protein involved in initiation of plasmid replication DNA replication, recombination, and repair 152973792 Common repB DNA replication KPN_pKPN5p08221 19 COG5527 COG5527, Protein involved in initiation of plasmid replication DNA replication, recombination, and repair 152973810 Pathogen - hypothetical protein KPN_pKPN5p08239 3 None None None 152973761 Common - hypothetical protein KPN_pKPN5p08190 20 None None None 152973744 Pathogen - hypothetical protein KPN_pKPN5p08173 5 None None None 152973768 Pathogen - hypothetical protein KPN_pKPN5p08197 1 None None None 152973781 Common - hypothetical protein KPN_pKPN5p08210 15 None None None 152973817 Common - putative transposase KPN_pKPN5p08246 48 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973772 Common - QacEdelta1; small multidrug resistance protein KPN_pKPN5p08201 141 COG2076 EmrE, Membrane transporters of cations and cationic drugs Inorganic ion transport and metabolism 152973804 Common - hypothetical protein KPN_pKPN5p08233 30 COG0456 RimI, Acetyltransferases General function prediction only 152973742 Common - putative antirestriction protein KPN_pKPN5p08171 14 None None None 152973784 Pathogen repC plasmid F repC-like protein, plasmid replication KPN_pKPN5p08213 1 None None None 152973794 Common parA plasmid partition protein A KPN_pKPN5p08223 143 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 152973738 Pathogen - hypothetical protein KPN_pKPN5p08167 1 None None None 152973755 Common - phosphoglucosamine mutase KPN_pKPN5p08184 208 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 152973774 Common int integrase KPN_pKPN5p08203 40 COG3795 COG3795, Uncharacterized protein conserved in bacteria Function unknown 152973783 Common pifA plasmid F pilA-like protein, phage inhibition KPN_pKPN5p08212 39 COG4928 COG4928, Predicted P-loop ATPase General function prediction only 152973788 Pathogen - hypothetical protein KPN_pKPN5p08217 1 None None None 152973762 Common - hypothetical protein KPN_pKPN5p08191 178 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 152973828 Common - putative alcohol dehydrogenase class III KPN_pKPN5p08257 102 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 152973765 Common aphA aminoglycoside 3'-phosphotransferase; APH I KPN_pKPN5p08194 23 COG3231 Aph, Aminoglycoside phosphotransferase Translation, ribosomal structure and biogenesis 152973740 Pathogen - hypothetical protein KPN_pKPN5p08169 3 None None None 152973786 Pathogen - hypothetical protein KPN_pKPN5p08215 2 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 152973736 Common - hypothetical protein KPN_pKPN5p08165 13 None None None 152973800 Common - putative transposase KPN_pKPN5p08229 48 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973748 Common - putative transposase KPN_pKPN5p08177 48 COG3316 COG3316, Transposase and inactivated derivatives DNA replication, recombination, and repair 152973807 Pathogen - hypothetical protein KPN_pKPN5p08236 3 None None None