Flavobacterium psychrophilum JIP02/86, complete genome NC_009613 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 150025877 Common - Putative 2 ,3-cyclic phosphodiesterase FP1834 78 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 150026340 Common - Protein of unknown function; putative adhesin FP2310 15 COG3291 COG3291, FOG: PKD repeat General function prediction only 150025684 Common - Glycosyl transferase, group 2 family protein FP1634 164 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150026087 Common rpoD RNA polymerase sigma-70 factor RpoD FP2048 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 150025314 Common - Glycosyl transferase, group 1 family protein FP1246 161 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150026302 Common - Probable ABC-type transport system, permease component FP2271 70 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 150024850 Common - hypothetical protein FP0757 4 None None None 150026444 Common - Probable ABC-type transport system, permease component FP2415 195 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 150025932 Common ppiB Probable peptidyl-prolyl cis-trans isomerase PpiB FP1890 209 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 150025432 Common dcp1 Peptidyl-dipeptidase Dcp1 FP1364 125 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 150025071 Common - Probable two-component system sensor histidine kinase FP0990 219 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150024651 Pathogen - hypothetical protein FP0554 1 None None None 150026358 Common bioA Adenosylmethionine--8-amino-7-oxononanoatetransa minase FP2328 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 150026403 Common - Probable saccharopine reductase FP2373 11 COG1748 LYS9, Saccharopine dehydrogenase and related proteins Amino acid transport and metabolism 150025860 Common - Probable metallo-beta-lactamase FP1815 208 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150026265 Common pbpC Membrane carboxypeptidase/penicillin-binding protein PbpC FP2234 199 COG4953 PbpC, Membrane carboxypeptidase/penicillin-binding protein PbpC Cell envelope biogenesis, outer membrane 150025328 Common - Glycosyl transferase, group 2 family protein FP1260 22 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 150026286 Common - hypothetical protein FP2255 21 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 150024972 Common - hypothetical protein FP0882 5 COG2365 COG2365, Protein tyrosine/serine phosphatase Signal transduction mechanisms 150025736 Common - Probable two-component system sensory protein FP1688 90 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 150025958 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase FP1916 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 150024768 Common - hypothetical protein FP0674 8 COG3296 COG3296, Uncharacterized protein conserved in bacteria Function unknown 150024938 Common - hypothetical protein FP0848 44 COG0714 COG0714, MoxR-like ATPases General function prediction only 150025087 Common - Probable M1 family metalloprotease FP1008 120 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 150024585 Common - Putative mobilization protein, TraG family FP0487 40 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 150024630 Common - Probable ABC-type multidrug transport system, ATPase and permease components FP0532 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150026242 Common - hypothetical protein FP2211 83 COG0433 COG0433, Predicted ATPase General function prediction only 150024392 Pathogen - hypothetical protein FP0286 1 None None None 150025268 Common rnhB ribonuclease HII FP1200 230 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 150025203 Common parA Chromosome partitioning protein ParA FP1131 230 COG1192 Soj, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150025485 Common - hypothetical protein FP1426 6 None None None 150024821 Common - Putative methyltransferase FP0728 59 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 150025830 Common - hypothetical protein FP1784 7 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 150024942 Pathogen - hypothetical protein FP0852 1 None None None 150024176 Common xth Exodeoxyribonuclease III FP0062 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 150024670 Common - hypothetical protein FP0575 2 None None None 150025951 Common pcm Protein-L-isoaspartate(D-aspartate)O-methyltrans ferase FP1909 156 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 150026150 Common yozB YozB protein FP2112 20 COG2322 COG2322, Predicted membrane protein Function unknown 150026153 Common - Probable outer membrane efflux protein precursor FP2115 77 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150025181 Common - hypothetical protein FP1108 2 None None None 150025370 Common - hypothetical protein FP1302 4 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 150025252 Common rplK 50S ribosomal protein L11 FP1180 247 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 150025218 Common - hypothetical protein FP1146 78 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 150026067 Common - hypothetical protein FP2028 147 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 150024751 Common - hypothetical protein FP0657 1 None None None 150025334 Common - TDP-4-oxo-6-deoxy-D-glucose transaminase FP1266 194 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 150026093 Common ftsQ Cell division protein FtsQ FP2055 6 None None None 150025924 Common - Probable TonB-dependent outer membrane receptorprecursor FP1882 12 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150025563 Common yiaD Probable lipoprotein YiaD precursor FP1507 168 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 150025693 Common - Putative translation factor FP1643 239 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 150025039 Common hisB imidazole glycerol-phosphate dehydratase/histidinol phosphatase FP0957 217 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 150024714 Common kup Probable potassium transport system protein Kup FP0619 89 COG3158 Kup, K+ transporter Inorganic ion transport and metabolism 150025802 Common - hypothetical protein FP1754 6 None None None 150025794 Common - TatD-related DNase FP1746 161 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 150024213 Pathogen - hypothetical protein FP0101 1 None None None 150025919 Common - Probable ABC-type multidrug transport system, ATPase and permease components FP1877 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 150025455 Common gldJ Gliding motility lipoprotein GldJ FP1389 67 COG1262 COG1262, Uncharacterized conserved protein Function unknown 150024458 Common - hypothetical protein FP0353 4 None None None 150024122 Common - hypothetical protein FP0008 3 None None None 150026410 Common rpmF 50S ribosomal protein L32 FP2380 13 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 150024482 Common - hypothetical protein FP0377 23 None None None 150025013 Common - Probable membrane fusion efflux protein precursor FP0931 138 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150026211 Pathogen - hypothetical protein FP2175 1 None None None 150026314 Common - hypothetical protein FP2283 2 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150026483 Common - hypothetical protein FP2455 62 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 150026161 Common maeB malic enzyme FP2123 214 COG0281 SfcA, Malic enzyme Energy production and conversion 150026235 Common - Probable phage protein FP2204 7 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 150025164 Common dnaN Probable DNA polymerase III, beta subunit FP1091 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 150024406 Common - Probable acetyltransferase, GNAT family FP0301 75 COG3153 COG3153, Predicted acetyltransferase General function prediction only 150024826 Common - hypothetical protein FP0733 2 None None None 150025785 Common - hypothetical protein FP1737 3 None None None 150025076 Common - 3-hydroxybutyryl-CoA dehydrogenase FP0997 159 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 150025773 Common - Acetyl-CoA C-acyltransferase FP1725 186 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 150024921 Pathogen - Probable transcriptional regulator, LuxR family FP0831 2 COG2909 MalT, ATP-dependent transcriptional regulator Transcription 150026433 Common - Probable transcriptional regulator, TetR family FP2404 32 COG1309 AcrR, Transcriptional regulator Transcription 150026320 Common - TatD-related DNase FP2289 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 150026110 Common dnaG DNA primase FP2072 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 150025008 Common - Probable membrane fusion efflux protein precursor FP0923 143 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150024780 Common - hypothetical protein FP0686 2 None None None 150025979 Common - hypothetical protein FP1937 25 None None None 150025463 Common - hypothetical protein FP1404 8 None None None 150025622 Common - hypothetical protein FP1571 3 None None None 150025980 Pathogen - hypothetical protein FP1938 3 COG3668 ParE, Plasmid stabilization system protein General function prediction only 150024290 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0180 17 None None None 150025114 Common - hypothetical protein FP1035 15 COG3320 COG3320, Putative dehydrogenase domain of multifunctional non-ribosomal peptide synthetases and related enzymes Secondary metabolites biosynthesis, transport, and catabolism 150024324 Pathogen - hypothetical protein FP0214 1 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 150026010 Common gldN Gliding motility protein GldN FP1970 4 None None None 150026006 Common - hypothetical protein FP1966 5 None None None 150024226 Common atpD F0F1 ATP synthase subunit beta FP0114 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 150024465 Common oprP Probable phosphate-selective porine FP0360 8 COG3746 OprP, Phosphate-selective porin Inorganic ion transport and metabolism 150025936 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein FP1894 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 150026521 Common glnS glutaminyl-tRNA synthetase FP2494 226 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 150024413 Common - hypothetical protein FP0308 133 COG2081 COG2081, Predicted flavoproteins General function prediction only 150025652 Common yyaK Protein of unknown function YyaK FP1602 23 None None None 150024599 Common kdsA 2-dehydro-3-deoxyphosphooctonate aldolase FP0501 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 150025707 Common - hypothetical protein FP1657 30 None None None 150026322 Common ansA Asparaginase 1 FP2291 125 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 150025645 Common - Probable transcriptional regulator, ArsR family FP1595 75 COG0640 ArsR, Predicted transcriptional regulators Transcription 150024794 Common - hypothetical protein FP0701 7 None None None 150026026 Common - hypothetical protein FP1986 2 None None None 150024904 Pathogen - hypothetical protein FP0814 1 None None None 150024116 Common - hypothetical protein FP0002 108 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 150025289 Common - hypothetical protein FP1221 39 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150025577 Common - Probable CRISPR-associated (Cas) protein. Cas2 family FP1526 21 COG3512 COG3512, Uncharacterized protein conserved in bacteria Function unknown 150024150 Common - hypothetical protein FP0036 3 None None None 150025106 Common ydcP Putative protease YdcP precursor FP1027 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 150025852 Common - Probable tRNA/rRNA methyltransferase FP1807 177 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 150025583 Common - hypothetical protein FP1532 4 None None None 150025239 Common surA Peptidyl-prolyl cis-trans isomerase precursor FP1167 137 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 150026459 Common - hypothetical protein FP2430 62 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 150025193 Common mutA Methylmalonyl-CoA mutase small subunit FP1121 109 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 150025727 Common - hypothetical protein FP1679 5 COG2127 COG2127, Uncharacterized conserved protein Function unknown 150025599 Common - hypothetical protein FP1548 2 None None None 150026408 Common accB Acetyl-CoA carboxylase, biotin carboxyl carrierprotein FP2378 170 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 150025848 Pathogen - hypothetical protein FP1803 1 None None None 150026428 Pathogen - hypothetical protein FP2398 1 None None None 150024312 Common rnc Ribonuclease III FP0202 213 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 150024677 Common - hypothetical protein FP0582 9 None None None 150024649 Pathogen - hypothetical protein FP0552 1 None None None 150026256 Common nuoG NADH dehydrogenase I, G subunit, N-terminal region FP2225 179 COG1034 NuoG, NADH dehydrogenase/NADH:ubiquinone oxidoreductase 75 kD subunit (chain G) Energy production and conversion 150025298 Pathogen - hypothetical protein FP1230 1 None None None 150024658 Pathogen - hypothetical protein FP0563 1 None None None 150025673 Common ddpX D-alanyl-D-alanine dipeptidase FP1623 56 COG2173 DdpX, D-alanyl-D-alanine dipeptidase Cell envelope biogenesis, outer membrane 150026225 Pathogen - hypothetical protein FP2189 2 None None None 150026368 Common - Probable proton-dependent di-tripeptide transporter FP2338 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 150025084 Common - Probable transcriptional regulator, AraC family FP1005 93 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150025815 Common - Probable thiamine diphosphokinase FP1767 28 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 150026509 Common - hypothetical protein FP2481 5 None None None 150025392 Common rplF 50S ribosomal protein L6 FP1324 239 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 150025914 Common wzxE Putative lipopolysaccharide biosynthesis protein WzxE FP1871 30 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150024316 Common - hypothetical protein FP0206 42 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 150025633 Common panE 2-dehydropantoate 2-reductase FP1582 74 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 150026070 Pathogen - hypothetical protein FP2031 1 None None None 150026386 Pathogen - hypothetical protein FP2356 1 None None None 150025078 Common - hypothetical protein FP0999 2 None None None 150026124 Common tig Trigger factor (TF) FP2086 176 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 150026055 Common - hypothetical protein FP2016 5 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150026512 Common - Putative Sec-independent protein translocase (twin-arginine translocation protein) FP2484 57 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 150025429 Common - hypothetical protein FP1361 1 None None None 150025296 Common mscS3 Probable small-conductance mechanosensitive ionchannel MscS3 FP1228 177 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 150025987 Common - hypothetical protein FP1945 50 COG3762 COG3762, Predicted membrane protein Function unknown 150024201 Common - Probable cytochrome c oxidase biogenesis protein FP0088 40 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 150025624 Pathogen - hypothetical protein FP1573 1 None None None 150025588 Common - hypothetical protein FP1537 3 COG1485 COG1485, Predicted ATPase General function prediction only 150024984 Common infC Translation initiation factor IF-3 FP0894 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 150025671 Common - hypothetical protein FP1621 11 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 150025422 Common - hypothetical protein FP1354 4 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 150025232 Common ccoH Probable cytochrome cbb3 oxidase maturation protein CcoH FP1160 4 None None None 150024498 Common mutS DNA mismatch repair protein FP0395 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 150025132 Common holA Probable DNA polymerase III, delta subunit FP1053 57 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 150025859 Common - Rhodanese-like domain protein FP1814 30 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 150026488 Common atpF ATP synthase B subunit FP2460 164 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 150024424 Common - Protein of unknown function precursor FP0319 29 COG5184 ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins Cell division and chromosome partitioning / Cytoskeleton 150024136 Common yceA Protein of unknown function YceA FP0022 120 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 150024141 Common - Probable type I endonuclease-methyltransferase fusion protein FP0027 96 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 150026298 Common - Acyl carrier protein FP2267 44 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150024382 Common - hypothetical protein FP0274 122 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 150024190 Common mntH Probable manganese transport protein mntH FP0076 113 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 150026174 Common - Probable modification methyltransferase FP2137 58 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 150024237 Common - hypothetical protein FP0125 3 None None None 150024693 Common cysS cysteinyl-tRNA synthetase FP0598 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150024385 Common - Probable cytosine/adenosine deaminase FP0277 210 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 150026334 Common - Probable lipoprotein precursor FP2304 2 None None None 150024540 Common - Probable exopolyphosphatase FP0437 35 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 150025553 Pathogen - hypothetical protein FP1497 1 None None None 150024146 Common - hypothetical protein FP0032 9 COG0417 PolB, DNA polymerase elongation subunit (family B) DNA replication, recombination, and repair 150025023 Pathogen - hypothetical protein FP0941 1 None None None 150025409 Common fusA elongation factor G FP1341 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 150024508 Common porR PorR protein, probably involved in biosynthesisof cell surface polysaccharide FP0405 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 150025654 Common - Probable TonB-dependent outer membrane receptorprecursor FP1604 18 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150025100 Common - Probable two-component system response regulatory protein FP1021 119 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150025049 Pathogen - hypothetical protein FP0967 1 None None None 150024867 Pathogen - hypothetical protein FP0777 1 None None None 150025040 Common hisC Histidinol-phosphate transaminase FP0958 227 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 150026305 Common hpaIIM Type II modification methyltransferase HpaII FP2274 135 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 150025134 Common - Glycosyl transferase, group 2 family protein FP1055 124 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 150024370 Common - Probable deoxynucleoside kinase FP0262 39 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 150024519 Common apaG ApaG FP0416 89 COG2967 ApaG, Uncharacterized protein affecting Mg2+/Co2+ transport Inorganic ion transport and metabolism 150025871 Common rprY Two-component system response regulatory protein RprY FP1826 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150026388 Common uppP Undecaprenyl-diphosphatase FP2358 197 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 150024246 Pathogen - hypothetical protein FP0134 1 None None None 150024683 Common - Probably involved in regulation of translation initiation FP0588 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150024477 Common - Cytochrome c family protein FP0372 26 COG3474 COG3474, Cytochrome c2 Energy production and conversion 150024517 Common gidB glucose-inhibited division protein B FP0414 194 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 150025878 Common - hypothetical protein FP1835 2 None None None 150024860 Pathogen - hypothetical protein FP0767 1 None None None 150025608 Common - hypothetical protein FP1557 8 None None None 150024606 Common trpB tryptophan synthase subunit beta FP0508 226 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 150025356 Common fnlA FnlA protein involved in UDP-L-FucpNAc biosynthesis (a nucleotide sugar precursor for antigen-O biosynthesis) FP1288 173 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150026132 Common - hypothetical protein FP2094 4 None None None 150024118 Common - Probable SAM-dependent methyltransferase FP0004 108 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150026462 Common - Protein of unknown function, putative outer membrane protein FP2433 7 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 150024335 Common hmgA Homogentisate 1,2-dioxygenase FP0225 53 COG3508 HmgA, Homogentisate 1,2-dioxygenase Secondary metabolites biosynthesis, transport, and catabolism 150024928 Common hutH1 Histidine ammonia-lyase FP0838 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 150024216 Common radA DNA repair protein RadA FP0104 214 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 150024681 Pathogen - hypothetical protein FP0586 1 None None None 150024464 Common phoR Two-component system sensor histidine kinase involved in phosphate regulation FP0359 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150024918 Pathogen - hypothetical protein FP0828 1 None None None 150024396 Common polA DNA polymerase I FP0290 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 150025648 Common - hypothetical protein FP1598 18 COG2263 COG2263, Predicted RNA methylase Translation, ribosomal structure and biogenesis 150024587 Common bmgA Probable mobilization protein BmgA FP0489 6 None None None 150024819 Common - hypothetical protein FP0726 29 None None None 150025246 Common - hypothetical protein FP1174 13 None None None 150025452 Common cdd Cytidine deaminase FP1386 109 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 150025517 Common cobU Bifunctional protein cobU : adenosylcobinamide kinase and adenosylcobinamide-phosphate guanylyltransferase FP1461 129 COG2087 CobU, Adenosyl cobinamide kinase/adenosyl cobinamide phosphate guanylyltransferase Coenzyme metabolism 150025714 Common ssb Single-strand DNA-binding protein Ssb FP1664 199 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 150024240 Common batD BatD protein FP0128 23 None None None 150024286 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0176 20 None None None 150025697 Common - Probable two-component system response regulatory protein FP1647 130 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150025537 Common - hypothetical protein FP1481 17 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 150026184 Common - Probable modification methyltransferase FP2147 58 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 150026284 Common - Probable coenzyme F390 synthetase FP2253 117 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 150025311 Common - Probable peptidase FP1243 31 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 150024342 Common fpp2 Psychrophilic metalloprotease Fpp2 precursor FP0232 12 None None None 150025510 Common - Protein of unknown function; putative anti ECF-type sigma factor FP1454 4 None None None 150026379 Common - Probable two-component system sensor histidine kinase FP2349 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150024703 Common - Probable superoxide dismutase FP0608 208 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 150024491 Common - hypothetical protein FP0386 2 None None None 150025718 Common mrp ATP-binding protein, Mrp/Nbp35 family FP1668 237 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150024675 Common - hypothetical protein FP0580 2 None None None 150024429 Common - Probable outer membrane protein precursor FP0324 17 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 150026176 Pathogen - hypothetical protein FP2139 1 None None None 150024536 Common thiH Thiazole biosynthesis protein ThiH FP0433 56 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 150024529 Common - Cation-transporting ATPase, P-type FP0426 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 150026300 Common - 3-oxoacyl-(acyl-carrier-protein) synthase FP2269 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150025745 Common - hypothetical protein FP1697 8 None None None 150024924 Common - Probable ABC-type multidrug transport system, ATPase and permease components FP0834 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150024364 Common - Homoserine dehydrogenase FP0255 197 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 150026278 Common trpS Tryptophan--tRNA ligase FP2247 231 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150024132 Common pgk phosphoglycerate kinase FP0018 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 150024300 Common - hypothetical protein FP0190 2 None None None 150025520 Common - Probable ABC-type iron(III)-transport system, permease component FP1464 192 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 150026345 Pathogen - hypothetical protein FP2315 1 None None None 150024227 Common atpC ATP synthase epsilon subunit FP0115 52 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 150024833 Common - hypothetical protein FP0740 2 None None None 150024614 Common - Probable transcriptional regulator, MarR-family FP0516 23 COG1846 MarR, Transcriptional regulators Transcription 150024660 Common - hypothetical protein FP0565 3 None None None 150026193 Common - Putative transporter FP2156 5 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 150024331 Common - hypothetical protein FP0221 53 COG3608 COG3608, Predicted deacylase General function prediction only 150024748 Common ddl D-alanyl-alanine synthetase A FP0653 213 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 150024795 Common - Probable peroxiredoxin FP0702 61 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150024911 Pathogen - hypothetical protein FP0821 1 None None None 150026148 Common - hypothetical protein FP2110 2 None None None 150026251 Common nuoL NADH dehydrogenase I, L subunit FP2220 210 COG1009 NuoL, NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit Energy production and conversion / Inorganic ion transport and metabolism 150025275 Common - hypothetical protein FP1207 154 COG0824 FcbC, Predicted thioesterase General function prediction only 150025592 Common - Major facilitator superfamily (MFS) permease FP1541 153 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150024185 Common - hypothetical protein FP0071 8 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 150024448 Common - hypothetical protein FP0343 1 None None None 150025917 Common trmD tRNA (guanine-N(1)-)-methyltransferase FP1874 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 150026396 Common greA Transcription elongation factor GreA FP2366 203 COG0782 GreA, Transcription elongation factor Transcription 150024152 Common - hypothetical protein FP0038 1 None None None 150024781 Common - Acetyltransferase, GNAT family FP0687 94 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150024349 Common queA S-adenosylmethionine:tRNA-ribosyltransferase-iso merase FP0240 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 150025491 Common rpmG 50S ribosomal protein L33 FP1432 61 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 150025885 Common - hypothetical protein FP1842 25 COG3007 COG3007, Uncharacterized paraquat-inducible protein B Function unknown 150025417 Common - recombination factor protein RarA FP1349 243 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 150025081 Common - Carboxyltransferase FP1002 143 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 150025995 Common - hypothetical protein FP1953 2 None None None 150026101 Common - hypothetical protein FP2063 2 None None None 150025259 Common - Acyl-CoA dehydrogenase family protein FP1191 161 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 150024281 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0171 18 None None None 150026271 Common - hypothetical protein FP2240 1 None None None 150026140 Common - hypothetical protein FP2102 73 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 150024220 Common panC Pantoate--beta-alanine ligase FP0108 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 150024997 Pathogen - hypothetical protein FP0912 1 None None None 150024802 Common - Putative phosphoesterase FP0709 27 COG0622 COG0622, Predicted phosphoesterase General function prediction only 150026038 Common - Glycosyl transferase, group 1 family protein FP1998 177 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150025185 Common pepX2 Xaa-Pro dipeptidyl-peptidase FP1112 107 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 150026466 Common - hypothetical protein FP2438 6 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 150025665 Common - hypothetical protein FP1615 10 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 150025867 Common pyrD Dihydroorotate oxidase FP1822 202 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 150025906 Common - hypothetical protein FP1863 24 None None None 150025402 Common rplV 50S ribosomal protein L22 FP1334 215 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 150025143 Common mur/alr putative bifunctional UDP-N-acetylmuramoyl-tripeptide:D-alanyl-D-alanine ligase/alanine racemase FP1064 209 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 150025410 Common rpsG 30S ribosomal protein S7 FP1342 222 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 150026316 Common - 3-oxoacyl-[acyl-carrier-protein] reductase FP2285 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150025839 Common - hypothetical protein FP1794 2 None None None 150026332 Common gspG Putative bacterial general secretion pathway protein G precursor FP2302 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 150025361 Common rmlA Glucose-1-phosphate thymidylyltransferase FP1293 233 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 150025198 Common - hypothetical protein FP1126 32 None None None 150025812 Common - putative ABC transporter ATP-binding protein FP1764 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150025663 Common gapA3 Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) FP1613 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 150025966 Common - hypothetical protein FP1924 2 COG4278 COG4278, Uncharacterized conserved protein Function unknown 150025756 Common speA Arginine decarboxylase FP1708 87 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 150025507 Common crtZ Carotene hydroxylase FP1451 14 None None None 150026204 Common rhuM RhuM protein FP2168 61 COG3943 COG3943, Virulence protein General function prediction only 150024874 Pathogen - hypothetical protein FP0784 1 None None None 150026155 Common - hypothetical protein FP2117 3 None None None 150026519 Common - hypothetical protein FP2491 9 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 150025187 Common - hypothetical protein FP1115 34 COG5373 COG5373, Predicted membrane protein Function unknown 150025450 Common pdhC Pyruvate dehydrogenase E2 component (dihydrolipoamide acetyltransferase) FP1384 196 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 150024494 Common umuC UmuC protein FP0389 180 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 150025067 Common - Probable modification methyltransferase FP0986 185 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 150024489 Common - hypothetical protein FP0384 1 None None None 150025825 Common corA Magnesium and cobalt transport protein CorA FP1779 167 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 150026069 Common sulP Probable sulfate permease FP2030 166 COG0659 SUL1, Sulfate permease and related transporters (MFS superfamily) Inorganic ion transport and metabolism 150026187 Common - Probable type II modification methyltransferase FP2150 131 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 150026523 Common - hypothetical protein FP2496 2 None None None 150024211 Common - Putative outer membrane protein FP0099 26 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 150026008 Common - hypothetical protein FP1968 3 None None None 150026091 Common ftsZ Cell division protein FtsZ FP2053 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 150024161 Common - Probable transmembrane protein of unknown function FP0047 66 COG1981 COG1981, Predicted membrane protein Function unknown 150025118 Common - MutS family protein FP1039 200 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 150024484 Common - Probable cytochrome c oxidase, subunit I precursor FP0379 175 COG0843 CyoB, Heme/copper-type cytochrome/quinol oxidases, subunit 1 Energy production and conversion 150025869 Pathogen - hypothetical protein FP1824 1 None None None 150026249 Common nuoN NADH dehydrogenase I, N subunit FP2218 208 COG1007 NuoN, NADH:ubiquinone oxidoreductase subunit 2 (chain N) Energy production and conversion 150026419 Common sufS Cysteine desulfurase, SufS FP2389 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 150025733 Common - hypothetical protein FP1685 1 None None None 150025804 Common - hypothetical protein FP1756 51 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 150024400 Common - Probable ABC-type transport system, permease component FP0294 115 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 150026197 Common - hypothetical protein FP2160 12 COG4938 COG4938, Uncharacterized conserved protein Function unknown 150024656 Pathogen - hypothetical protein FP0561 1 None None None 150026446 Common mreB Rod shape-determining protein MreB FP2417 212 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 150025191 Common udk Uridine kinase FP1119 107 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 150026139 Common - hypothetical protein FP2101 3 None None None 150026233 Pathogen - hypothetical protein FP2202 1 None None None 150025947 Common - hypothetical protein FP1905 13 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 150025112 Common - Probable ribosomal-protein-amino-adic N-acetyltransferase FP1033 110 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150026130 Common - hypothetical protein FP2092 5 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 150025483 Common - Probable ABC-type transport system, ATPase and permease components FP1424 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150025626 Pathogen - hypothetical protein FP1575 1 None None None 150025761 Common - hypothetical protein FP1713 4 None None None 150026213 Common - hypothetical protein FP2177 12 COG0714 COG0714, MoxR-like ATPases General function prediction only 150025183 Common cphB Cyanophycinase FP1110 25 COG4242 CphB, Cyanophycinase and related exopeptidases Secondary metabolites biosynthesis, transport, and catabolism / Inorganic ion transport and metabolism 150025015 Common - Probable outer membrane efflux protein precursor FP0933 115 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150025179 Common - RNA polymerase ECF-type sigma factor FP1106 168 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150025250 Common rplJ 50S ribosomal protein L10 FP1178 179 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 150024408 Common - hypothetical protein FP0303 3 None None None 150024120 Common - Protein of unknown function; putative adhesin FP0006 12 None None None 150025227 Common - Probable acyl-[acyl-carrier-protein] desaturase FP1155 10 None None None 150025272 Common hemL Glutamate-1-semialdehyde aminotransferase FP1204 237 COG0001 HemL, Glutamate-1-semialdehyde aminotransferase Coenzyme metabolism 150024631 Common vdh Valine dehydrogenase FP0533 175 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 150024578 Common - Probable peptidase FP0480 29 COG2234 Iap, Predicted aminopeptidases General function prediction only 150025481 Common maf Maf-like protein FP1422 184 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 150024326 Pathogen - hypothetical protein FP0216 1 None None None 150024836 Common - Glycosyl transferase, group 1 family protein FP0743 64 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150026202 Common - hypothetical protein FP2166 60 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150024299 Common ahcY S-adenosyl-L-homocysteine hydrolase FP0189 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 150025686 Common - hypothetical protein FP1636 9 None None None 150026034 Common - Probable rRNA methyltransferase FP1994 158 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 150025175 Common - hypothetical protein FP1102 1 None None None 150025544 Common - Probable vitamin K-dependent gamma-carboxylase FP1488 7 None None None 150026253 Common nuoJ NADH dehydrogenase I, J subunit FP2222 155 COG0839 NuoJ, NADH:ubiquinone oxidoreductase subunit 6 (chain J) Energy production and conversion 150026338 Common - hypothetical protein FP2308 26 COG3209 RhsA, Rhs family protein Cell envelope biogenesis, outer membrane 150025006 Common lolD Lipoprotein releasing system ATP-binding protein LolD FP0921 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150026025 Common groL 60 kDa chaperonin GroEL FP1985 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 150025999 Common hutU urocanate hydratase FP1957 97 COG2987 HutU, Urocanate hydratase Amino acid transport and metabolism 150026293 Common - hypothetical protein FP2262 6 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 150024302 Common mfd Transcription-repair coupling factor FP0192 225 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 150024390 Common dgt Deoxyguanosinetriphosphate triphosphohydrolase (dGTPase) FP0282 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 150025846 Common - hypothetical protein FP1801 2 None None None 150024940 Common - Probable transcriptional regulator, AraC family FP0850 123 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150024467 Common pstC ABC-type phosphate-transport system, permease component PstC FP0362 231 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 150025434 Common - hypothetical protein FP1366 2 None None None 150024607 Common trpF Phosphoribosylanthranilate isomerase FP0509 161 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 150025089 Common recG ATP-dependent DNA helicase RecG FP1010 220 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 150025054 Common - hypothetical protein FP0973 2 None None None 150024948 Common - Probable type II modification methyltransferase FP0858 107 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 150025305 Common yhbG Probable ABC-type transport system, ATPase component YhbG FP1237 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 150026108 Common nadE NH(3)-dependent NAD(+) synthetase FP2070 216 COG0171 NadE, NAD synthase Coenzyme metabolism 150025220 Common - Rhomboid family protein FP1148 102 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 150024362 Common - Probable transcriptional regulator, AraC family FP0253 87 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150026423 Common sufB cysteine desulfurase activator complex subunit SufB FP2393 183 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 150026442 Common claF Protein of unknown function; putative adhesin FP2413 27 None None None 150025200 Common dapB Dihydrodipicolinate reductase FP1128 214 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 150024600 Common - Major facilitator superfamily (MFS) permease FP0502 198 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150025266 Common - hypothetical protein FP1198 5 None None None 150024737 Common fdx1 Ferredoxin FP0642 89 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 150026507 Common rmlC dTDP-4-dehydrorhamnose 3,5-epimerase FP2479 168 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 150024712 Common - hypothetical protein FP0617 10 None None None 150025390 Common rpsE 30S ribosomal protein S5 FP1322 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 150026001 Common - Protein of unknown function; putative adhesin FP1959 7 None None None 150024265 Common - hypothetical protein FP0155 16 COG2887 COG2887, RecB family exonuclease DNA replication, recombination, and repair 150024350 Common aroA 3-phosphoshikimate 1-carboxyvinyltransferase FP0241 229 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 150024558 Common rpsI 30S ribosomal protein S9 FP0455 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 150026514 Common czcD Cation efflux system protein CzcD FP2486 219 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 150025759 Common nupG Major facilitator superfamily (MFS), H+ Symporter (NHS) family, nucleoside permease FP1711 29 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 150024554 Pathogen - hypothetical protein FP0451 1 None None None 150025316 Common - Hexapeptide transferase family protein FP1248 199 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 150024629 Common - hypothetical protein FP0531 7 None None None 150025797 Common - Probable transcriptional regulator FP1749 33 COG3682 COG3682, Predicted transcriptional regulator Transcription 150025405 Common rplW 50S ribosomal protein L23 FP1337 205 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 150026159 Common sprA SprA protein FP2121 6 None None None 150025508 Common - hypothetical protein FP1452 2 None None None 150025399 Common rpmC 50S ribosomal protein L29 FP1331 18 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 150026366 Common - Thioredoxin family protein FP2336 10 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 150025290 Common - Pseudouridylate synthase FP1222 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 150024705 Common tgt Queuine tRNA-ribosyltransferase FP0610 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 150024961 Common - Cysteine synthase/cystathionine beta-synthase family protein FP0871 228 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 150025497 Common - Probable DNA polymerase III subunit FP1438 133 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 150025940 Common - hypothetical protein FP1898 42 COG3530 COG3530, Uncharacterized protein conserved in bacteria Function unknown 150025420 Common radC DNA repair protein RadC FP1352 175 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 150025169 Common - Probable esterase FP1096 98 COG0400 COG0400, Predicted esterase General function prediction only 150026486 Common atpA F0F1 ATP synthase subunit alpha FP2458 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 150024590 Pathogen - hypothetical protein FP0492 1 None None None 150025427 Common adk Adenylate kinase FP1359 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 150024906 Pathogen - hypothetical protein FP0816 1 None None None 150024571 Common - hypothetical protein FP0468 30 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 150024374 Common - hypothetical protein FP0266 2 None None None 150025470 Common - Probable sugar O-acetyltransferase precursor FP1411 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 150024178 Common - Putative phosphoglycerate dehydrogenase FP0064 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 150024986 Pathogen - hypothetical protein FP0901 1 None None None 150025974 Common - RNA polymerase ECF-type sigma factor FP1932 78 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150026391 Pathogen - hypothetical protein FP2361 1 None None None 150025439 Common - hypothetical protein FP1373 22 COG2346 COG2346, Truncated hemoglobins General function prediction only 150024380 Common - hypothetical protein FP0272 2 None None None 150024787 Common - Protein of unknown function related to microcinresistance protein McbG FP0694 40 COG1357 COG1357, Uncharacterized low-complexity proteins Function unknown 150024923 Pathogen - hypothetical protein FP0833 1 None None None 150024310 Common acpP Acyl carrier protein FP0200 210 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150024357 Common engC ribosome-associated GTPase FP0248 163 COG1162 COG1162, Predicted GTPases General function prediction only 150024734 Common serA Phosphoglycerate dehydrogenase FP0639 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 150025818 Common - hypothetical protein FP1770 79 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 150025150 Common - hypothetical protein FP1077 5 None None None 150025540 Common apbE Membrane-associated lipoprotein involved in thiamine biosynthesis FP1484 138 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 150025375 Common - Amidinotransferase family protein FP1307 21 COG1834 COG1834, N-Dimethylarginine dimethylaminohydrolase Amino acid transport and metabolism 150024292 Common - hypothetical protein FP0182 6 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 150026267 Pathogen - hypothetical protein FP2236 1 None None None 150025817 Common aroE Shikimate dehydrogenase FP1769 219 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 150024422 Common - Putative transcriptional regulator FP0317 2 None None None 150024858 Common aroC chorismate synthase FP0765 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 150025387 Common secY preprotein translocase subunit SecY FP1319 228 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 150025501 Common pyrR2 Bifunctional protein : pyrimidine operon regulatory protein and uracil phosphoribosyltransferase FP1442 85 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 150024538 Common pyrH UMP kinase FP0435 243 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 150025985 Common - Probable transcriptional regulator, MerR family FP1943 93 COG0789 SoxR, Predicted transcriptional regulators Transcription 150026012 Common gldL Gliding motility protein GldL FP1972 6 None None None 150025561 Common - hypothetical protein FP1505 184 COG0661 AarF, Predicted unusual protein kinase General function prediction only 150026329 Common gspD Putative bacterial general secretion pathway protein D precursor FP2299 136 COG1450 PulD, Type II secretory pathway, component PulD Cell motility and secretion / Intracellular trafficking and secretion 150026119 Common - O-methyltransferase FP2081 98 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 150024314 Common pykA Pyruvate kinase FP0204 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 150026227 Common - hypothetical protein FP2196 51 COG3876 COG3876, Uncharacterized protein conserved in bacteria Function unknown 150024244 Common batA BatA protein FP0132 88 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 150025916 Common rplS 50S ribosomal protein L19 FP1873 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 150024622 Common asd Aspartate-semialdehyde dehydrogenase FP0524 236 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 150025850 Common purB adenylosuccinate lyase FP1805 235 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 150025771 Common - 3-hydroxyacyl-CoA dehydrogenase/enoyl-CoA hydratase/isomerase family protein FP1723 163 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 150026179 Pathogen - hypothetical protein FP2142 1 None None None 150026180 Pathogen - hypothetical protein FP2143 1 None None None 150025725 Common yncA Probable phosphinothricin N-acetyltransferase YncA FP1677 113 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 150026400 Common - Probable TonB-dependent outer membrane receptorprecursor FP2370 70 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150026373 Pathogen - hypothetical protein FP2343 1 None None None 150025461 Common - Protein of unknown function precursor FP1402 6 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 150024456 Common - Probable drug/metabolite-transporting permease FP0351 104 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 150025934 Common gldI Gliding motility lipoprotein GldI FP1892 3 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 150024898 Common - Putative S49 family serine protease FP0808 126 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150025650 Common - Putative UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase FP1600 144 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 150024197 Common - hypothetical protein FP0084 2 None None None 150026436 Common - hypothetical protein FP2407 1 None None None 150024553 Common ilvE Branched-chain-amino-acid transaminase FP0450 217 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 150025127 Common tal putative translaldolase FP1048 152 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 150025606 Pathogen - hypothetical protein FP1555 1 None None None 150024612 Common - hypothetical protein FP0514 23 COG2353 COG2353, Uncharacterized conserved protein Function unknown 150026072 Common - Probable TonB-dependent outer membrane receptorprecursor FP2033 24 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 150024278 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0168 34 None None None 150024817 Common - hypothetical protein FP0724 2 None None None 150024306 Common purF Amidophosphoribosyltransferase FP0196 231 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 150024979 Common - hypothetical protein FP0889 1 COG5473 COG5473, Predicted integral membrane protein Function unknown 150024957 Common - hypothetical protein FP0867 3 None None None 150026182 Pathogen - hypothetical protein FP2145 1 None None None 150025331 Common - hypothetical protein FP1263 39 COG3274 COG3274, Uncharacterized protein conserved in bacteria Function unknown 150025712 Common - Protein of unknown function; putative adhesin FP1662 4 None None None 150025556 Common - Probable TonB-dependent outer membrane receptorprecursor FP1500 25 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150025519 Common - Probable ABC-type iron(III)-transport system, binding protein precursor component FP1463 30 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 150024333 Common - Probable esterase of the alpha-beta hydrolase superfamily FP0223 130 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 150024932 Common - hypothetical protein FP0842 18 COG2866 COG2866, Predicted carboxypeptidase Amino acid transport and metabolism 150026057 Common aroQ 3-dehydroquinate dehydratase FP2018 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 150024242 Common batB BatB protein FP0130 59 COG1240 ChlD, Mg-chelatase subunit ChlD Coenzyme metabolism 150024790 Common rsmB Ribosomal RNA small subunit methyltransferase B FP0697 209 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 150025513 Common - Probable TonB-dependent outer membrane receptorprecursor FP1457 92 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 150025778 Common catG Bi-functional catalase-peroxidase FP1730 98 COG0376 KatG, Catalase (peroxidase I) Inorganic ion transport and metabolism 150026336 Pathogen - hypothetical protein FP2306 1 None None None 150024797 Common - hypothetical protein FP0704 2 None None None 150025845 Common - hypothetical protein FP1800 1 None None None 150024691 Pathogen - hypothetical protein FP0596 1 None None None 150025555 Common - Protein of unknown function; putative adhesin FP1499 8 None None None 150024138 Common gldH Gliding motility protein GldH FP0024 5 None None None 150026324 Common - hypothetical protein FP2294 4 None None None 150024771 Common - Probable lipoprotein FP0677 10 None None None 150026282 Common - Probable exporter FP2251 74 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 150025397 Common rplN 50S ribosomal protein L14 FP1329 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 150024855 Common - Glycosyl transferase, group 1 family protein FP0762 230 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150024148 Common - Cytochrome c551/c552 family protein FP0034 2 COG4654 COG4654, Cytochrome c551/c552 Energy production and conversion 150025215 Common - Probable secreted M23/M37 family peptidase FP1143 171 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 150026172 Common gpmI phosphoglyceromutase FP2135 125 COG0696 GpmI, Phosphoglyceromutase Carbohydrate transport and metabolism 150026479 Common - Probable polysaccharide biosynthesis protein FP2451 62 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 150025799 Common - Holliday junction resolvase-like protein FP1751 108 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 150024506 Common - hypothetical protein FP0403 12 None None None 150026490 Common atpB ATP synthase A subunit FP2462 187 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 150024963 Common prfB Peptide chain release factor 2 (RF-2) FP0873 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 150024504 Common - hypothetical protein FP0401 19 None None None 150024809 Common - hypothetical protein FP0716 5 None None None 150024372 Pathogen - hypothetical protein FP0264 1 None None None 150024869 Pathogen - hypothetical protein FP0779 1 None None None 150024154 Common - hypothetical protein FP0040 4 COG3187 HslJ, Heat shock protein Posttranslational modification, protein turnover, chaperones 150025344 Common - Probable polysaccharide exporter precursor FP1276 69 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 150024479 Common - Probable molybdopterin oxidoreductase, membranesubunit FP0374 39 COG5557 COG5557, Polysulphide reductase Energy production and conversion 150025647 Pathogen - hypothetical protein FP1597 1 None None None 150024669 Common glcD (S)-2-hydroxy-acid oxidase FP0574 201 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 150024469 Common pstB ABC-type phosphate-transport system, ATPase component PstB FP0364 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 150026296 Common - 3-oxoacyl-(acyl-carrier-protein) synthase FP2265 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150024847 Common - Probable Fe-S oxidoreductase N-terminal region FP0754 67 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 150025904 Common - Glycosyl transferase, group 2 family protein FP1861 20 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 150024420 Common - Pseudouridylate synthase FP0315 203 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 150024515 Common aspC1 Probable aspartate transaminase AspC1 FP0412 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150026063 Common yjgM Probable acetyltransferase YjgM FP2024 61 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150025529 Common lpxK Tetraacyldisaccharide 4'-kinase FP1473 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 150025895 Common - Probable two-component system response regulatory protein FP1852 162 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150025025 Common - Probable exonuclease FP0943 34 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 150025828 Common ftnA Ferritin FP1782 80 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 150024865 Pathogen - hypothetical protein FP0775 1 None None None 150025389 Common rpmD 50S ribosomal protein L30 FP1321 61 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 150026468 Common - Probable M23/M37 family peptidase FP2440 12 COG4942 COG4942, Membrane-bound metallopeptidase Cell division and chromosome partitioning 150025475 Common - Probable penicillin-binding protein FP1416 48 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 150025069 Common - Probable TonB-dependent outer membrane receptorprecursor FP0988 12 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150024273 Common - Probable lipoprotein precursor FP0163 2 None None None 150025701 Common - Putative two-component system sensor, no kinasedomain FP1651 66 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 150024990 Common - hypothetical protein FP0905 10 None None None 150025059 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase FP0978 172 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 150026453 Pathogen - Probable lipoprotein precursor FP2424 1 None None None 150024800 Common - hypothetical protein FP0707 20 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 150025997 Common - Probable lipoprotein precursor FP1955 20 None None None 150024993 Common sucC Succinyl-CoA synthetase, beta subunit FP0908 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 150024470 Common phoU Phosphate transport system protein PhoU FP0365 191 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 150024168 Common - Hydrolase, haloacid dehalogenase family protein FP0054 23 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 150025400 Common rplP 50S ribosomal protein L16 FP1332 217 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 150024619 Common - Probable TonB-dependent outer membrane receptor precursor FP0521 5 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150024840 Common clpA ATPase with chaperone activity ATP-binding subunit FP0747 219 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 150025635 Common - hypothetical protein FP1584 2 None None None 150025109 Common - hypothetical protein FP1030 18 None None None 150024432 Common ubiE Ubiquinone/menaquinone biosynthesis methyltransferase UbiE FP0327 224 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150025574 Common - Two-component system response regulatory protein FP1523 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150024344 Common bioB Biotin synthase FP0234 174 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 150025196 Pathogen - hypothetical protein FP1124 1 None None None 150026221 Pathogen - hypothetical protein FP2185 1 None None None 150024394 Pathogen - hypothetical protein FP0288 1 None None None 150026356 Common thiL Thiamine-phosphate kinase FP2326 199 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 150024999 Common - Probable peroxiredoxin FP0914 221 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150024288 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0178 15 None None None 150025407 Common rplC 50S ribosomal protein L3 FP1339 238 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 150025758 Common - hypothetical protein FP1710 2 None None None 150026258 Common nuoF NADH dehydrogenase I, F subunit FP2227 166 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 150025716 Common hupA Histone-like bacterial DNA-binding protein HU-alpha FP1666 199 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 150025968 Common - hypothetical protein FP1926 17 None None None 150024838 Common - hypothetical protein FP0745 69 COG2323 COG2323, Predicted membrane protein Function unknown 150025930 Common - Probable aminopeptidase precursor FP1888 50 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 150025278 Common - Probable methyltransferase FP1210 208 COG0313 COG0313, Predicted methyltransferases General function prediction only 150025141 Common - hypothetical protein FP1062 2 None None None 150024891 Common ibrB Protein of unknown function IbrB FP0801 17 COG1475 Spo0J, Predicted transcriptional regulators Transcription 150024569 Common - hypothetical protein FP0466 2 None None None 150025382 Common rpsD 30S ribosomal protein S4 FP1314 227 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 150025613 Common - hypothetical protein FP1562 35 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 150024282 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0172 20 None None None 150025095 Common - Protein of unknown function containing an heme NO Binding domain FP1016 20 None None None 150025060 Common - Probable phosphohydrolase FP0979 89 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 150025225 Common ccoI Probable cytochrome cbb3 oxidase maturation protein CcoI FP1153 230 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 150025677 Common dsbD Thiol:disulfide interchange protein DsbD precursor FP1627 107 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 150025443 Common - Glycosyl transferase, group 2 family protein FP1377 75 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150025257 Common xerC Tyrosine recombinase XerC FP1189 225 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150025539 Common - hypothetical protein FP1483 4 None None None 150026199 Common - hypothetical protein FP2162 11 None None None 150025341 Pathogen - hypothetical protein FP1273 1 None None None 150026049 Common recQ2 ATP-dependent DNA helicase RecQ2 FP2010 234 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 150024746 Common - Probable 23S rRNA pseudouridine synthase FP0651 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 150025783 Common lpdA1 Dihydrolipoyl dehydrogenase FP1735 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 150026163 Common ruvB Holliday junction DNA helicase B FP2125 229 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 150024253 Common gpsA Glycerol-3-phosphate dehydrogenase (NAD(P)+) FP0141 211 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 150026089 Common - hypothetical protein FP2050 25 COG3228 COG3228, Uncharacterized protein conserved in bacteria Function unknown 150024159 Common - Probable transcriptional regulator, AraC family FP0045 34 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150025522 Common - RNA polymerase ECF-type sigma factor FP1466 159 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150026394 Common - Probable M48 family membrane-associated zinc metalloprotease precursor FP2364 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 150026146 Common - Cytochrome c oxidase family protein FP2108 16 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 150025585 Common - hypothetical protein FP1534 17 COG2253 COG2253, Uncharacterized conserved protein Function unknown 150025961 Common pepT peptidase T FP1919 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 150024134 Common elaA ElaA protein FP0020 88 COG2153 ElaA, Predicted acyltransferase General function prediction only 150025415 Common - Probable tRNA/rRNA methyltransferase FP1347 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 150025789 Common - Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase family protein FP1741 189 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 150026190 Common - hypothetical protein FP2153 2 None None None 150024183 Common - hypothetical protein FP0069 35 COG4823 AbiF, Abortive infection bacteriophage resistance protein Defense mechanisms 150025926 Common smpB SsrA-binding protein FP1884 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 150026189 Pathogen - hypothetical protein FP2152 1 None None None 150026457 Common - hypothetical protein FP2428 7 COG5019 CDC3, Septin family protein Cell division and chromosome partitioning / Cytoskeleton 150024527 Common cat2 4-hydroxybutyrate coenzyme A transferase FP0424 100 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 150024912 Common - hypothetical protein FP0822 4 COG1423 COG1423, ATP-dependent DNA ligase, homolog of eukaryotic ligase III DNA replication, recombination, and repair 150025883 Common - hypothetical protein FP1840 6 None None None 150025102 Common - Probable cell surface protein FP1023 16 COG3291 COG3291, FOG: PKD repeat General function prediction only 150026464 Pathogen - hypothetical protein FP2436 1 None None None 150024229 Pathogen - hypothetical protein FP0117 1 None None None 150025321 Common - Hexapeptide transferase family protein FP1253 195 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 150024814 Common - Probable ribonuclease FP0721 16 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 150025594 Common tetX Tetracycline resistance protein FP1543 49 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 150026499 Common upp uracil phosphoribosyltransferase FP2471 163 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 150024926 Common gcvT glycine cleavage system aminomethyltransferase T FP0836 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 150025976 Common - Probable acyltransferase FP1934 2 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 150024222 Common - hypothetical protein FP0110 2 None None None 150026051 Common - hypothetical protein FP2012 1 None None None 150025573 Common - Two-component system response regulatory protein FP1517 205 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150026127 Pathogen - Putative ABC-type transport system, permease component FP2089 1 None None None 150026014 Common - hypothetical protein FP1974 3 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 150026080 Common phrB2 Deoxyribodipyrimidine photolyase PhrB2 FP2041 131 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 150025983 Common alaS alanyl-tRNA synthetase FP1941 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150025373 Pathogen - hypothetical protein FP1305 1 None None None 150024304 Common - hypothetical protein FP0194 135 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 150024901 Pathogen - hypothetical protein FP0811 1 None None None 150025234 Common - hypothetical protein FP1162 28 COG2841 COG2841, Uncharacterized protein conserved in bacteria Function unknown 150025992 Common - Probable ABC-type multidrug transport system, ATPase and permease components FP1950 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150026098 Common mraY Phospho-N-acetylmuramoyl-pentapeptide-transferase FP2060 212 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 150025770 Common - Probable transcriptional regulator, MarR-family FP1722 44 COG1846 MarR, Transcriptional regulators Transcription 150025221 Common - Rhomboid family protein FP1149 18 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 150024206 Common sdhA succinate dehydrogenase flavoprotein subunit FP0093 225 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 150025495 Common - hypothetical protein FP1436 2 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 150024731 Common - hypothetical protein FP0636 3 None None None 150024914 Pathogen - hypothetical protein FP0824 1 None None None 150024171 Common - hypothetical protein FP0057 1 None None None 150025844 Common - hypothetical protein FP1799 14 COG4485 COG4485, Predicted membrane protein Function unknown 150024269 Common - Probable ATP-dependent DNA helicase, UvrD/REP family FP0159 208 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 150024602 Common - Probable outer membrane efflux protein precursor FP0504 87 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150025955 Common - hypothetical protein FP1913 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 150026177 Common - hypothetical protein FP2140 4 None None None 150025171 Common phnP PhnP protein FP1098 95 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 150024532 Common thiE1 Thiamine-phosphate diphosphorylase FP0429 17 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 150024834 Common - hypothetical protein FP0741 2 None None None 150025285 Common gapA2 glyceraldehyde-3-phosphate dehydrogenase FP1217 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 150026349 Pathogen - hypothetical protein FP2319 1 None None None 150026229 Common - Putative methyltransferase FP2198 10 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150025098 Common - Probable two-component system sensor histidine kinase FP1019 222 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 150025425 Common obgE GTPase ObgE FP1357 249 COG0536 Obg, Predicted GTPase General function prediction only 150025445 Common - Probable ABC-type transport system, ATPase component FP1379 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 150024702 Common - Probable Acyl CoA binding protein FP0607 6 COG4281 ACB, Acyl-CoA-binding protein Lipid metabolism 150024885 Pathogen - hypothetical protein FP0795 1 None None None 150024620 Common phuR Probable TonB-dependent outer membrane hemin receptor precursor PhuR FP0522 110 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150025291 Common - Probable ion transporter FP1223 95 None None None 150024980 Common mscS1 Probable small-conductance mechanosensitive ionchannel MscS1 FP0890 164 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 150026157 Common - hypothetical protein FP2119 1 COG5652 COG5652, Predicted integral membrane protein Function unknown 150024674 Common - Probable cytochrome c peroxidase FP0579 93 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 150025148 Common - hypothetical protein FP1069 2 None None None 150024654 Pathogen - hypothetical protein FP0559 1 None None None 150025453 Common - hypothetical protein FP1387 7 None None None 150026059 Common xerD Tyrosine recombinase XerD FP2020 230 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150024881 Pathogen - hypothetical protein FP0791 1 None None None 150024263 Common pepP Xaa-Pro aminopeptidase FP0153 227 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 150026247 Common rpmA 50S ribosomal protein L27 FP2216 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 150024262 Common - hypothetical protein FP0152 6 None None None 150024642 Common glnA Glutamate--ammonia ligase FP0545 67 COG3968 COG3968, Uncharacterized protein related to glutamine synthetase General function prediction only 150026289 Common - hypothetical protein FP2258 2 None None None 150024627 Common secDF bifunctional preprotein translocase subunit SecD/SecF FP0529 218 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 150026170 Common - hypothetical protein FP2133 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 150024931 Common - Putative transcriptional regulator, XRE family FP0841 6 COG4800 COG4800, Predicted transcriptional regulator with an HTH domain Transcription 150025945 Common fur Ferric iron uptake transcription regulator, Fur FP1903 164 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 150024878 Pathogen - hypothetical protein FP0788 1 None None None 150026135 Common - Probable outer membrane protein, OmpH family FP2097 12 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 150026477 Common - Probable sugar phosphate nucleotydyl transferase FP2449 236 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 150025136 Pathogen - hypothetical protein FP1057 1 None None None 150025153 Common - Probable short-chain type dehydrogenase FP1080 226 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 150024700 Common cdsA Phosphatidate cytidylyltransferase FP0605 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 150026208 Pathogen - hypothetical protein FP2172 1 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 150024633 Common - hypothetical protein FP0535 8 None None None 150025281 Common - hypothetical protein FP1213 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 150024486 Common - hypothetical protein FP0381 2 None None None 150025723 Common - hypothetical protein FP1675 11 None None None 150026033 Common - Pseudouridylate synthase FP1993 202 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 150025709 Common - Probable ABC-type transport system, ATPase component FP1659 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150026422 Common sufC Fe-S assembly ATPase, SufC FP2392 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 150025016 Common - Probable universal stress protein FP0934 131 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 150025167 Common pyrC2 Dihydroorotase FP1094 202 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 150026502 Common capK Putative capsular polysaccharide biosynthesis protein CapK FP2474 62 COG1541 PaaK, Coenzyme F390 synthetase Coenzyme metabolism 150025074 Common - hypothetical protein FP0993 2 COG4270 COG4270, Predicted membrane protein Function unknown 150025435 Common - hypothetical protein FP1367 3 None None None 150026295 Common - 3-oxoacyl-(acyl-carrier-protein) synthase FP2264 9 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150024352 Common - hypothetical protein FP0243 33 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 150025489 Common ftsY Cell division protein FtsY FP1430 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 150026269 Common - Probable TonB-dependent outer membrane receptorprecursor FP2238 7 None None None 150025897 Common - hypothetical protein FP1854 32 COG4731 COG4731, Uncharacterized protein conserved in bacteria Function unknown 150025873 Common coaE Dephospho-CoA kinase FP1828 210 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 150024950 Common - Putative aminotransferase FP0860 201 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 150025173 Common - Probable peroxiredoxin FP1100 218 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150024297 Common pcrB geranylgeranylglyceryl phosphate synthase-like protein FP0187 26 COG1646 COG1646, Predicted phosphate-binding enzymes, TIM-barrel fold General function prediction only 150024726 Common - hypothetical protein FP0631 22 None None None 150026417 Common sufE Cysteine desulfuration protein, SufE FP2387 97 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 150025368 Common recR Recombination protein RecR FP1300 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 150024234 Common - Probable acyl-protein synthetase FP0122 21 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150024764 Common dnaJ Chaperone protein DnaJ FP0670 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 150026344 Common - hypothetical protein FP2314 2 None None None 150024717 Common - hypothetical protein FP0622 1 None None None 150025264 Common - Cysteine synthase/cystathionine beta-synthase family protein FP1196 222 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 150024377 Common recO DNA repair protein RecO FP0269 7 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 150026425 Common - Putative metal-dependent hydrolase FP2395 45 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 150026440 Common - Probable outer membrane protein, OmpA family FP2411 144 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 150024710 Common trxB1 Thioredoxin-disulfide reductase FP0615 245 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 150026077 Common - hypothetical protein FP2038 25 None None None 150025689 Common - Glycosyl transferase, group 1 family protein FP1639 26 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150025680 Common lpsA Lipopolysaccharide core biosynthesis protein LpsA FP1630 8 None None None 150026310 Common darB 3-oxoacyl-(acyl carrier protein) synthase III FP2279 147 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 150025206 Common - Probable sugar phosphate nucleotydyl transferase FP1134 50 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 150024750 Common - hypothetical protein FP0656 57 COG2120 COG2120, Uncharacterized proteins, LmbE homologs Function unknown 150024581 Common - hypothetical protein FP0483 11 None None None 150026413 Common ribE riboflavin synthase subunit alpha FP2383 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 150024959 Common - Putative translation factor FP0869 235 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 150026022 Common - hypothetical protein FP1982 6 None None None 150024588 Pathogen bmgB Probable mobilization protein BmgB FP0490 1 None None None 150024188 Common - hypothetical protein FP0074 3 COG0723 QcrA, Rieske Fe-S protein Energy production and conversion 150024160 Common hemH Ferrochelatase FP0046 148 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 150025110 Common - Translation initiation factor SUI1 family protein FP1031 58 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 150024496 Pathogen - hypothetical protein FP0391 1 None None None 150025430 Common purK Phosphoribosylaminoimidazole carboxylase ATPasesubunit FP1362 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 150025715 Common mutY A/G-specific adenine glycosylase FP1665 225 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 150025256 Common - hypothetical protein FP1188 5 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 150025065 Common - Probable transcriptional regulator, AraC family FP0984 11 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150026239 Common exbD Biopolymer transport ExbD protein FP2208 7 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 150026144 Common cyoE Protoheme IX farnesyltransferase FP2106 167 COG0109 CyoE, Polyprenyltransferase (cytochrome oxidase assembly factor) Posttranslational modification, protein turnover, chaperones 150026232 Pathogen - hypothetical protein FP2201 1 None None None 150024419 Common - Prenyltransferase family protein FP0314 30 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 150026137 Common murI Glutamate racemase FP2099 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 150026375 Common prc Carboxy-terminal processing protease precursor FP2345 183 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150026260 Common nuoD NADH dehydrogenase I, D subunit FP2229 191 COG0649 NuoD, NADH:ubiquinone oxidoreductase 49 kD subunit 7 Energy production and conversion 150025303 Common tatC Sec-independent protein secretion pathway component TatC FP1235 204 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 150025827 Common - Probable ferredoxin FP1781 11 COG3411 COG3411, Ferredoxin Energy production and conversion 150024609 Common trpD Anthranilate phosphoribosyltransferase FP0511 217 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 150026317 Common - hypothetical protein FP2286 25 None None None 150025833 Common - hypothetical protein FP1788 2 None None None 150025702 Common - hypothetical protein FP1652 2 None None None 150024403 Common - hypothetical protein FP0297 14 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 150024561 Common nrdB Ribonucleoside-diphosphate reductase, beta subunit FP0458 135 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 150026002 Common - hypothetical protein FP1960 5 None None None 150024853 Common - hypothetical protein FP0760 2 None None None 150025325 Common neuA N-acylneuraminate cytidylyltransferase FP1257 75 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 150024707 Common - hypothetical protein FP0612 40 COG2962 RarD, Predicted permeases General function prediction only 150024196 Common - hypothetical protein FP0083 212 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 150024934 Common - hypothetical protein FP0844 6 None None None 150025864 Common - HAM1 protein homolog FP1819 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 150025280 Common - hypothetical protein FP1212 4 None None None 150024359 Common aspC3 Probable aspartate transaminase AspC3 FP0250 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150024410 Common - Probable glycosidase FP0305 173 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 150024825 Common - hypothetical protein FP0732 3 None None None 150024126 Common - hypothetical protein FP0012 2 None None None 150025806 Common - hypothetical protein FP1758 82 COG3193 GlcG, Uncharacterized protein, possibly involved in utilization of glycolate and propanediol General function prediction only 150024970 Common - Probable multidrug resistance protein precursor. AcrB/AcrD/AcrF family protein FP0880 176 COG3696 COG3696, Putative silver efflux pump Inorganic ion transport and metabolism 150025117 Common ung Uracil-DNA glycosylase FP1038 128 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 150025160 Common - hypothetical protein FP1087 4 COG1359 COG1359, Uncharacterized conserved protein Function unknown 150025460 Common - hypothetical protein FP1401 1 None None None 150025005 Common - Cytochrome c oxidase family protein FP0920 150 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 150024744 Common parC DNA topoisomerase IV subunit A FP0649 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 150025309 Common - hypothetical protein FP1241 8 None None None 150026525 Common - Protein of unknown function similar to several eukaryotic hypersensitive-induced response proteins FP2498 185 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 150024524 Common - Probable ABC-type transport system, membrane fusion efflux protein component FP0421 88 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150024845 Common - Probable N-acetylmuramoyl-L-alanine amidase FP0752 173 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150024483 Common - Probable cytochrome c oxidase, subunit II precursor FP0378 116 COG1622 CyoA, Heme/copper-type cytochrome/quinol oxidases, subunit 2 Energy production and conversion 150025704 Common - hypothetical protein FP1654 2 None None None 150025524 Pathogen - hypothetical protein FP1468 1 None None None 150024967 Pathogen - hypothetical protein FP0877 1 None None None 150026105 Common engB GTPase EngB FP2067 185 COG0218 COG0218, Predicted GTPase General function prediction only 150024285 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0175 22 None None None 150026040 Common - Thioredoxin family protein FP2000 235 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 150026019 Common - hypothetical protein FP1979 234 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 150026165 Common - Probable aminopeptidase FP2127 41 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 150025928 Common - Probable ribosomal-protein-amino-adic N-acetyltransferase FP1886 132 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150024773 Common - hypothetical protein FP0679 4 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 150025570 Pathogen - hypothetical protein FP1514 1 None None None 150025603 Pathogen - hypothetical protein FP1552 1 None None None 150026451 Common nucA Probable DNA/RNA non-specific endonuclease FP2422 46 COG1864 NUC1, DNA/RNA endonuclease G, NUC1 Nucleotide transport and metabolism 150024345 Pathogen - hypothetical protein FP0235 1 COG5178 PRP8, U5 snRNP spliceosome subunit RNA processing and modification 150025739 Common kdpB Potassium-transporting ATPase B subunit FP1691 232 COG2216 KdpB, High-affinity K+ transport system, ATPase chain B Inorganic ion transport and metabolism 150025323 Common neuC UDP-N-acetylglucosamine 2-epimerase FP1255 127 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 150025072 Common - hypothetical protein FP0991 2 None None None 150024755 Common dbpA ATP-dependent RNA helicase DbpA FP0661 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150024617 Common ftsE Probable cell division ATP-binding protein FtsE FP0519 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 150024610 Common pabA Para-aminobenzoate/anthranilate synthase glutamine amidotransferase component II FP0512 236 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 150025969 Common anmK anhydro-N-acetylmuramic acid kinase FP1927 120 COG2377 COG2377, Predicted molecular chaperone distantly related to HSP70-fold metalloproteases Posttranslational modification, protein turnover, chaperones 150025386 Common infA translation initiation factor IF-1 FP1318 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 150026275 Common - Protein of unknown function; putative adhesin FP2244 31 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 150025269 Common lipB Lipoyltransferase FP1201 168 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 150026455 Common - hypothetical protein FP2426 10 None None None 150024664 Common norM Multidrug resistance protein norM (Na(+)/drug antiporter) FP0569 164 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 150025011 Common - hypothetical protein FP0929 88 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 150024459 Common - Cys/Met metabolism PLP-dependent enzyme FP0354 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 150025477 Common - Probable cytochrome c-type biogenesis protein precursor FP1418 117 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 150024329 Common lspA Signal peptidase II FP0219 62 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150025889 Common - hypothetical protein FP1846 1 None None None 150024946 Common - Putative two-component system sensor histidine kinase FP0856 13 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150025569 Common - Probable drug/metabolite-transporting permease FP1513 15 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 150026469 Common - hypothetical protein FP2441 4 None None None 150024259 Common prsA ribose-phosphate pyrophosphokinase FP0147 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 150024438 Common thyA Thymidylate synthase FP0333 138 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 150025751 Common - hypothetical protein FP1703 12 COG4907 COG4907, Predicted membrane protein Function unknown 150025302 Common kdsD Arabinose-5-phosphate isomerase FP1234 146 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 150025433 Common - Tryptophan repeat gene family protein FP1365 2 None None None 150025121 Common - Probably involved in regulation of translation initiation FP1042 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150025637 Common - Probable acetyl-CoA acetyltransferase FP1586 180 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 150025638 Common - Probable transcriptional regulator, TetR family FP1587 82 COG1309 AcrR, Transcriptional regulator Transcription 150025962 Common - Probable outer membrane protein, OmpA family FP1920 159 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 150025668 Common - hypothetical protein FP1618 11 None None None 150024373 Common - Putative outer membrane protein FP0265 4 None None None 150026117 Common - Probable lipoprotein precursor FP2079 1 None None None 150024722 Common - hypothetical protein FP0627 7 COG3311 AlpA, Predicted transcriptional regulator Transcription 150025558 Common - hypothetical protein FP1502 5 None None None 150025766 Common mrsB1 protein-methionine-S-oxide reductase MrsB1 FP1718 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 150024308 Common rnhA Ribonuclease HI FP0198 168 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 150024640 Common - Putative biopolymer transporter FP0543 3 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 150024181 Common mgtE Mg2+ transporter MgtE FP0067 173 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 150025597 Common - hypothetical protein FP1546 2 None None None 150024258 Common rplY 50S ribosomal protein L25/general stress protein Ctc FP0146 179 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 150024592 Pathogen - hypothetical protein FP0494 1 None None None 150024368 Common - Thioredoxin family protein FP0260 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 150024208 Common sdhB succinate dehydrogenase/fumarate reductase iron-sulfur subunit FP0095 70 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 150025414 Common - hypothetical protein FP1346 5 None None None 150025365 Common wbpP UDP-N-acetylglucosamine C4 epimerase FP1297 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150024893 Pathogen - hypothetical protein FP0803 1 None None None 150026035 Common - Probable ABC-type iron(III)-transport system, ATPase component FP1995 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 150024252 Common phnA PhnA protein FP0140 95 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 150025880 Common - Probable lipoprotein FP1837 103 COG4105 ComL, DNA uptake lipoprotein General function prediction only 150025836 Common ygcM Probable 6-pyruvoyltetrahydrobiopterin synthase FP1791 95 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 150025615 Pathogen - hypothetical protein FP1564 2 None None None 150025691 Common rmd GDP-4-dehydro-D-rhamnose reductase FP1641 221 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150025763 Common - Major facilitator superfamily (MFS) permease FP1715 73 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 150024156 Common hemD Uroporphyrinogen-III synthase FP0042 13 COG1587 HemD, Uroporphyrinogen-III synthase Coenzyme metabolism 150024199 Common pepO M13 family metallopeptidase PepO precursor FP0086 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 150024548 Common ilvA threonine dehydratase FP0445 207 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 150024539 Common frr Ribosome recycling factor FP0436 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 150025055 Common - Probable UDP-N-acetylglucosamine acyltransferase FP0974 171 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 150025042 Common hisG ATP phosphoribosyltransferase FP0960 211 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 150025729 Common - hypothetical protein FP1681 1 None None None 150024165 Common - Putative acyl-[acyl-carrier-protein] desaturase FP0051 10 None None None 150026326 Common - hypothetical protein FP2296 3 COG0464 SpoVK, ATPases of the AAA+ class Posttranslational modification, protein turnover, chaperones 150025901 Common yjeB Protein of unknown function YjeB FP1858 93 COG1959 COG1959, Predicted transcriptional regulator Transcription 150025533 Common - hypothetical protein FP1477 49 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 150024544 Common - Probable Na+/H+ antiporter FP0441 199 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 150024564 Pathogen - hypothetical protein FP0461 1 None None None 150024698 Common ftsH Cell division protein FtsH FP0603 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 150025346 Common - Probable aminotransferase FP1278 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 150024831 Common - hypothetical protein FP0738 38 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 150024530 Common thiS Thiamine biosynthesis protein ThiS FP0427 7 COG2104 ThiS, Sulfur transfer protein involved in thiamine biosynthesis Coenzyme metabolism 150025874 Common - Glycosyl transferase, group 2 family protein FP1829 124 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150025490 Common - hypothetical protein FP1431 2 None None None 150025856 Common - Probable outer membrane efflux protein precursor FP1811 68 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150025899 Common nadC Nicotinate-nucleotide diphosphorylase (carboxylating) FP1856 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 150026160 Common ruvA Holliday junction DNA helicase RuvA FP2122 211 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 150025027 Common - Probable ATP-dependent RNA helicase, DEAD/DEAH box family FP0945 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150024441 Common etfB Electron transfer flavoprotein, beta subunit FP0336 149 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 150026495 Common - hypothetical protein FP2467 8 None None None 150025822 Common nhaA Na+/H+ antiporter FP1774 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 150024399 Common - Probable polysaccharide deacetylase FP0293 109 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150024812 Common - Putative pyruvate/branched-chain alpha-keto acid dehydrogenase (E1) component, alpha and beta subunits FP0719 174 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 150025530 Common - Putative acetyltransferase, GNAT family FP1474 26 COG0456 RimI, Acetyltransferases General function prediction only 150025151 Common - Probable M42 family peptidase FP1078 83 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 150025600 Pathogen - hypothetical protein FP1549 1 None None None 150024149 Common hemB delta-aminolevulinic acid dehydratase FP0035 220 COG0113 HemB, Delta-aminolevulinic acid dehydratase Coenzyme metabolism 150025710 Common - Probable ABC-type transport system, permease component FP1660 7 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 150026290 Common - Probable dehydratase FP2259 4 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 150024431 Common porT PorT protein FP0326 5 None None None 150026339 Common - hypothetical protein FP2309 29 COG3236 COG3236, Uncharacterized protein conserved in bacteria Function unknown 150024687 Pathogen - hypothetical protein FP0592 1 None None None 150024863 Common - Probable acetyl-CoA acetyltransferase FP0770 177 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 150025744 Common aspC2 aspartate aminotransferase FP1696 241 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 150025798 Common - Putative antirepressor FP1750 14 COG4219 MecR1, Antirepressor regulating drug resistance, predicted signal transduction N-terminal membrane component Transcription / Signal transduction mechanisms 150025001 Common - Probable transcriptional regulator, AraC family FP0916 77 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150025156 Pathogen - hypothetical protein FP1083 1 None None None 150024960 Common ptrB Protease II (Oligopeptidase B) FP0870 101 COG1770 PtrB, Protease II Amino acid transport and metabolism 150026354 Common - hypothetical protein FP2324 2 None None None 150024907 Pathogen - hypothetical protein FP0817 1 None None None 150024503 Common - Putative outer membrane protein FP0400 8 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 150024871 Pathogen - hypothetical protein FP0781 1 None None None 150024450 Common rimM 16S rRNA processing protein RimM FP0345 121 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 150025357 Common wbuA Probable rhamnosyl transferase FP1289 36 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 150026487 Common atpH ATP synthase delta subunit FP2459 170 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 150025781 Common - Cys/Met metabolism PLP-dependent enzyme FP1733 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 150025352 Common wbuB Probable L-fucosamine transferase FP1284 71 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150025515 Common cobS Adenosylcobinamide-GDP ribazoletransferase FP1459 116 COG0368 CobS, Cobalamin-5-phosphate synthase Coenzyme metabolism 150025641 Common lolA Outer-membrane lipoprotein carrier protein precursor LolA FP1591 5 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 150025842 Common - Glycosyl transferase, group 1 family protein FP1797 32 None None None 150025213 Common - hypothetical protein FP1141 4 None None None 150026188 Pathogen - hypothetical protein FP2151 1 None None None 150026047 Common hupB Histone-like bacterial DNA-binding protein HU-beta FP2008 207 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 150025990 Common - hypothetical protein FP1948 4 None None None 150024583 Common - hypothetical protein FP0485 9 None None None 150024513 Pathogen - hypothetical protein FP0410 1 None None None 150025128 Common - Probable short-chain type dehydrogenase FP1049 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 150024338 Common - Tryptophan 2,3-dioxygenase FP0228 40 COG3483 TDO2, Tryptophan 2,3-dioxygenase (vermilion) Amino acid transport and metabolism 150025395 Common rplE 50S ribosomal protein L5 FP1327 248 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 150026383 Common - Probable membrane-associated esterase FP2353 6 COG2267 PldB, Lysophospholipase Lipid metabolism 150025915 Common icd isocitrate dehydrogenase FP1872 66 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 150026437 Common kgd alpha-ketoglutarate decarboxylase FP2408 147 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 150025244 Common prfC Peptide chain release factor 3 (RF-3) FP1172 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 150024239 Common batE BatE protein FP0127 26 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 150025732 Common - hypothetical protein FP1684 7 COG2391 COG2391, Predicted transporter component General function prediction only 150024550 Common ilvH Acetolactate synthase, small subunit FP0447 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 150024276 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0166 22 None None None 150025567 Common - hypothetical protein FP1511 32 COG5267 COG5267, Uncharacterized protein conserved in bacteria Function unknown 150025617 Common - Probable modification methyltransferase FP1566 51 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 150024679 Common - Probable ABC-type transport system, ATPase component FP0584 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150024753 Common - hypothetical protein FP0659 91 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 150026254 Common nuoI NADH dehydrogenase I, I subunit FP2223 188 COG1143 NuoI, Formate hydrogenlyase subunit 6/NADH:ubiquinone oxidoreductase 23 kD subunit (chain I) Energy production and conversion 150024672 Common - hypothetical protein FP0577 2 None None None 150025587 Pathogen - hypothetical protein FP1536 1 None None None 150024811 Common - hypothetical protein FP0718 78 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 150024887 Pathogen - hypothetical protein FP0797 2 None None None 150024883 Pathogen - hypothetical protein FP0793 2 None None None 150024843 Common yjgF Protein of unknown function YjgF FP0750 179 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 150025912 Common - hypothetical protein FP1869 8 None None None 150025705 Common - Protein of unknown function; putative adhesin FP1655 12 COG3291 COG3291, FOG: PKD repeat General function prediction only 150024204 Pathogen - hypothetical protein FP0091 1 None None None 150024644 Pathogen - hypothetical protein FP0547 1 None None None 150025796 Common - Major facilitator superfamily (MFS) permease FP1748 154 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150026510 Common - hypothetical protein FP2482 13 None None None 150024626 Common mdh Malate dehydrogenase FP0528 192 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 150025294 Common - hypothetical protein FP1226 35 COG4680 COG4680, Uncharacterized protein conserved in bacteria Function unknown 150025742 Common - Probable sigma-54 dependent two-component system response regulatory protein FP1694 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150025155 Common - hypothetical protein FP1082 71 COG1912 COG1912, Uncharacterized conserved protein Function unknown 150026133 Common uppS Di-trans,poly-cis-decaprenylcistransferase FP2095 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 150026216 Pathogen - hypothetical protein FP2180 1 None None None 150024791 Common - hypothetical protein FP0698 2 None None None 150024260 Common - ArgE/DapE/Acy1 family protein FP0150 148 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 150024395 Common - Probable penicillin-binding protein FP0289 124 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 150025437 Common - hypothetical protein FP1371 2 None None None 150024982 Common rplT 50S ribosomal protein L20 FP0892 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 150024511 Common fabD Malonyl CoA-acyl carrier protein transacylase FP0408 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 150025749 Common - Probable ATP-dependent RNA helicase, DEAD/DEAH box family FP1701 239 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150025978 Common - hypothetical protein FP1936 3 None None None 150024318 Common - Probable coproporphyrinogen oxidase FP0208 207 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 150025283 Common dapF Diaminopimelate epimerase FP1215 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 150025091 Common - hypothetical protein FP1012 23 COG4276 COG4276, Uncharacterized conserved protein Function unknown 150025423 Common - Protein of unknown function ; putative S46 family serine protease FP1355 21 COG3591 COG3591, V8-like Glu-specific endopeptidase Amino acid transport and metabolism 150024572 Common nusA transcription elongation factor NusA FP0469 218 COG0195 NusA, Transcription elongation factor Transcription 150025312 Common - Probable glycosyl transferase FP1244 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 150024520 Common - Protein of unknown function precursor FP0417 6 None None None 150026053 Common murA UDP-N-acetylglucosamine 1-carboxyvinyltransferase FP2014 209 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 150026381 Common - hypothetical protein FP2351 6 None None None 150026016 Common - hypothetical protein FP1976 6 None None None 150024473 Common trmB tRNA (guanine-N(7)-)-methyltransferase FP0368 146 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 150026395 Common - hypothetical protein FP2365 2 COG2146 {NirD}, Ferredoxin subunits of nitrite reductase and ring-hydroxylating dioxygenases Inorganic ion transport and metabolism / General function prediction only 150026347 Common - hypothetical protein FP2317 151 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 150026031 Common - hypothetical protein FP1991 5 None None None 150025989 Pathogen - hypothetical protein FP1947 5 None None None 150025236 Common acnA aconitate hydratase FP1164 223 COG1048 AcnA, Aconitase A Energy production and conversion 150024903 Pathogen - hypothetical protein FP0813 1 None None None 150024730 Common - hypothetical protein FP0635 2 None None None 150025994 Common - hypothetical protein FP1952 8 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 150025131 Common - hypothetical protein FP1052 2 None None None 150024267 Common kbl 2-amino-3-ketobutyrate coenzyme A ligase FP0157 193 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 150025505 Common crtI Phytoene dehydrogenase FP1449 89 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 150025775 Common - hypothetical protein FP1727 2 None None None 150025138 Common adeC Adenine deaminase FP1059 69 COG1001 AdeC, Adenine deaminase Nucleotide transport and metabolism 150026194 Pathogen - hypothetical protein FP2157 1 None None None 150025854 Common - Probable multidrug resistance protein precursor. AcrB/AcrD/AcrF family protein FP1809 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150024783 Common - hypothetical protein FP0689 4 None None None 150026129 Common pdxJ pyridoxal phosphate biosynthetic protein PdxJ FP2091 139 COG0854 PdxJ, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 150025195 Common mutB methylmalonyl-CoA mutase FP1123 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 150025082 Common - hypothetical protein FP1003 9 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150026406 Common rnpA Ribonuclease P protein component FP2376 12 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 150026175 Common - hypothetical protein FP2138 5 None None None 150024804 Pathogen - hypothetical protein FP0711 1 None None None 150024291 Common - hypothetical protein FP0181 2 None None None 150026506 Common rmlD dTDP-4-dehydrorhamnose reductase FP2478 172 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 150024173 Common - hypothetical protein FP0059 109 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 150026361 Common - hypothetical protein FP2331 2 None None None 150025240 Common - Probable peptidyl-prolyl cis-trans isomerase precursor FP1168 154 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 150026115 Common - RNA polymerase ECF-type sigma factor FP2077 152 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150024736 Common - hypothetical protein FP0641 4 None None None 150025738 Common kdpC Potassium-transporting ATPase C subunit FP1690 95 COG2156 KdpC, K+-transporting ATPase, c chain Inorganic ion transport and metabolism 150024586 Pathogen - hypothetical protein FP0488 1 None None None 150024952 Common - Rhomboid family protein FP0862 81 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 150024944 Common - Phosphoglucomutase/phosphomannomutase family protein FP0854 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 150025347 Common - Putative acetyltransferase FP1279 90 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 150026378 Common - Probable oxidoreductase FP2348 61 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 150026044 Common - hypothetical protein FP2005 6 None None None 150026312 Common - hypothetical protein FP2281 72 COG1233 COG1233, Phytoene dehydrogenase and related proteins Secondary metabolites biosynthesis, transport, and catabolism 150025307 Common pssA CDP-diacylglycerol--serineO-phosphatidyltransfera se FP1239 131 COG1183 PssA, Phosphatidylserine synthase Lipid metabolism 150025813 Common cplB ATPase with chaperone activity ATP-binding subunit FP1765 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 150025003 Common - hypothetical protein FP0918 2 None None None 150025953 Common - 3-hydroxyacyl-CoA dehydrogenase family protein FP1911 160 COG1250 FadB, 3-hydroxyacyl-CoA dehydrogenase Lipid metabolism 150024823 Common - hypothetical protein FP0730 1 None None None 150025354 Common fnlB FnlB protein involved in UDP-L-FucpNAc biosynthesis (a nucleotide sugar precursor for antigen-O bisynthesis) FP1286 21 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150025254 Common secE Preprotein translocase SecE subunit FP1182 3 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 150025338 Common - Probable ABC-type polysaccharide/polyol phosphate transport system, permease component FP1270 106 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 150026004 Common era GTP-binding protein Era FP1962 223 COG1159 Era, GTPase General function prediction only 150025695 Common coxA Cytochrome c oxidase assembly protein FP1645 52 COG1612 CtaA, Uncharacterized protein required for cytochrome oxidase assembly Posttranslational modification, protein turnover, chaperones 150025063 Common - Probable ATP-dependent exodeoxyribonuclease FP0982 84 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 150026319 Common - Putative dehydrogenase/oxidoreductase FP2288 74 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 150026411 Common - hypothetical protein FP2381 7 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 150025378 Common - Putative outer membrane protein FP1310 8 COG2312 COG2312, Erythromycin esterase homolog General function prediction only 150024417 Common - hypothetical protein FP0312 2 None None None 150026230 Common - Putative transporter FP2199 5 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 150026096 Common ftsW Cell division protein FtsW FP2058 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 150026359 Common bioD Dethiobiotin synthetase FP2329 149 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 150025721 Pathogen - hypothetical protein FP1671 1 None None None 150024977 Common - Probable 23S rRNA pseudouridine synthase FP0887 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 150024124 Common - hypothetical protein FP0010 3 None None None 150024724 Pathogen - hypothetical protein FP0629 1 None None None 150025188 Common - hypothetical protein FP1116 3 None None None 150025831 Common - Probable TonB-dependent outer membrane receptorprecursor FP1785 120 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150026237 Common - Putative ABC-type phosphate-transport system, binding protein precursor component FP2206 11 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 150026485 Common atpG ATP synthase gamma subunit FP2457 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 150025834 Common manA Mannose-6-phosphate isomerase FP1789 54 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 150025921 Common - Protein of unknown function related to arylsulfatase regulator (Fe-S oxidoreductase) FP1879 41 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 150025808 Common - hypothetical protein FP1760 2 None None None 150024454 Common - hypothetical protein FP0349 26 None None None 150025247 Common rpoC DNA-directed RNA polymerase subunit beta' FP1175 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 150024218 Common - hypothetical protein FP0106 25 COG0392 COG0392, Predicted integral membrane protein Function unknown 150024789 Common - Probable extracellular ribonuclease precursor FP0696 22 COG2356 EndA, Endonuclease I DNA replication, recombination, and repair 150026415 Common - hypothetical protein FP2385 4 None None None 150026473 Pathogen - hypothetical protein FP2445 1 None None None 150025480 Common ubiA prenyltransferase FP1421 39 COG0382 UbiA, 4-hydroxybenzoate polyprenyltransferase and related prenyltransferases Coenzyme metabolism 150024194 Common - Probable M50 family membrane-associated zinc metalloprotease precursor FP0081 211 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 150025162 Common gldF Gliding motility protein GldF FP1089 45 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 150026206 Common - hypothetical protein FP2170 12 None None None 150024728 Common mrsA Protein-methionine-S-oxide reductase MsrA FP0633 205 COG0225 MsrA, Peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 150024488 Pathogen - hypothetical protein FP0383 1 None None None 150026079 Common - hypothetical protein FP2040 45 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 150026420 Common - Probable penicillin-binding protein FP2390 64 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 150025018 Common - Probable transmembrane protein precursor FP0936 3 COG5617 COG5617, Predicted integral membrane protein Function unknown 150025034 Common - hypothetical protein FP0952 3 None None None 150026021 Common - hypothetical protein FP1981 7 None None None 150025841 Common pyrR1 Bifunctional protein : pyrimidine operon regulatory protein and uracil phosphoribosyltransferase FP1796 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 150024715 Common - hypothetical protein FP0620 10 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 150025682 Common - Glycosyl transferase, group 2 family protein FP1632 111 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150025051 Common ppk Polyphosphate kinase FP0969 161 COG0855 Ppk, Polyphosphate kinase Inorganic ion transport and metabolism 150026122 Common clpX ATP-dependent protease ATP-binding subunit FP2084 225 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 150024471 Common - Probable glycosyl transferase FP0366 6 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 150026500 Common - hypothetical protein FP2472 2 None None None 150024295 Common - Probable bifunctional protein : transcriptionalregulator NadR family and of unknown function FP0185 39 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 150025223 Common - hypothetical protein FP1151 1 None None None 150026028 Common carB carbamoyl phosphate synthase large subunit FP1988 236 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 150025465 Common - Two-component system response regulatory protein FP1406 224 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150025487 Common tlpA Putative thiol:disulfide oxidoreductase TlpA FP1428 23 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 150025208 Common - hypothetical protein FP1136 2 None None None 150025340 Pathogen - hypothetical protein FP1272 1 None None None 150024379 Common gdhA glutamate dehydrogenase FP0271 169 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 150024719 Common - Probable phosphatase/phosphohexomutase FP0624 194 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 150026352 Common - hypothetical protein FP2322 3 None None None 150026342 Common - hypothetical protein FP2312 2 None None None 150024832 Common rocD Ornithine--oxo-acid transaminase FP0739 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 150026308 Common darC2 Probable acyl carrier protein involved in flexirubin-type pigment biosynthesis DarC2 FP2277 3 COG4706 COG4706, Predicted 3-hydroxylacyl-(acyl carrier protein) dehydratase Lipid metabolism 150025201 Common - hypothetical protein FP1129 7 None None None 150026449 Common pbpA Penicillin-binding protein 2 FP2420 206 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150025262 Common - hypothetical protein FP1194 7 None None None 150026240 Common - hypothetical protein FP2209 5 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 150025287 Common yqfO Protein of unknown function YqfO FP1219 98 COG0327 COG0327, Uncharacterized conserved protein Function unknown 150026401 Common lpxH UDP-2,3-diacylglucosamine hydrolase FP2371 48 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 150025801 Common def peptide deformylase FP1753 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 150024186 Common serS seryl-tRNA synthetase FP0072 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 150025096 Common - Probable two-component system sensor histidine kinase FP1017 221 COG4251 COG4251, Bacteriophytochrome (light-regulated signal transduction histidine kinase) Signal transduction mechanisms 150025300 Common - hypothetical protein FP1232 1 None None None 150025753 Common rnz ribonuclease Z FP1705 111 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 150024436 Common - hypothetical protein FP0331 2 None None None 150026037 Common asnB Asparagine synthetase [glutamine-hydrolyzing] FP1997 169 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 150025720 Common trxB2 Thioredoxin-disulfide reductase FP1670 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 150025158 Common - hypothetical protein FP1085 18 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 150025964 Common fhuA Probable TonB-dependent outer membrane ferrichrome-iron receptor precursor FhuA FP1922 118 COG4773 FhuE, Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid Inorganic ion transport and metabolism 150024322 Common - hypothetical protein FP0212 2 None None None 150025923 Pathogen - hypothetical protein FP1881 1 None None None 150025579 Common - hypothetical protein FP1528 10 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 150024480 Common - hypothetical protein FP0375 18 None None None 150025012 Common - hypothetical protein FP0930 1 None None None 150025384 Common rpsM 30S ribosomal protein S13 FP1316 237 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 150025768 Common fadD Long-chain-fatty-acid--CoA ligase FP1720 215 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 150024696 Common birA Probable biotin--[acetyl-CoA-carboxylase] ligase FP0601 216 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 150024742 Common - hypothetical protein FP0647 31 None None None 150025363 Common ugd UDP-glucose 6-dehydrogenase FP1295 207 COG1004 Ugd, Predicted UDP-glucose 6-dehydrogenase Cell envelope biogenesis, outer membrane 150025371 Common - MarC family integral membrane protein precursor FP1303 158 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 150024501 Common - Probable bifunctional protein : 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine diphosphokinase and deoxynucleoside kinase FP0398 136 COG1428 COG1428, Deoxynucleoside kinases Nucleotide transport and metabolism 150024851 Common - Probable beta-N-acetylglucosaminidase precursor FP0758 188 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 150025440 Common fabH1 3-oxoacyl-[acyl-carrier-protein] synthase III protein FabH1 FP1374 205 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 150024895 Pathogen - hypothetical protein FP0805 1 None None None 150024542 Common - hypothetical protein FP0439 11 None None None 150025548 Common - hypothetical protein FP1492 2 None None None 150024876 Pathogen - hypothetical protein FP0786 2 None None None 150024223 Common glmS Glucosamine--fructose-6-phosphate aminotransferase [isomerizing] FP0111 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 150025447 Common manC Mannose-1-phosphate guanylyltransferase (GDP) FP1381 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 150024387 Common dxs 1-deoxy-D-xylulose-5-phosphate synthase FP0279 207 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 150024414 Common - Probable integral membrane protein FP0309 60 COG3476 COG3476, Tryptophan-rich sensory protein (mitochondrial benzodiazepine receptor homolog) Signal transduction mechanisms 150026082 Common phrB3 Deoxyribodipyrimidine photolyase PhrB3 FP2043 132 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 150025526 Common gapA1 Glyceraldehyde-3-phosphate dehydrogenase (phosphorylating) FP1470 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 150024192 Common - hypothetical protein FP0078 6 None None None 150024384 Common - Probable cold shock protein FP0276 179 COG1278 CspC, Cold shock proteins Transcription 150024163 Common crt Probable 3-hydroxybutyryl-CoA dehydratase FP0049 187 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 150025943 Common - hypothetical protein FP1901 17 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 150024662 Common - hypothetical protein FP0567 2 COG3211 PhoX, Predicted phosphatase General function prediction only 150025580 Pathogen - hypothetical protein FP1529 1 None None None 150024130 Common sprB Putative adhesin precursor SprB FP0016 94 None None None 150024534 Common thiE2 Thiamine-phosphate diphosphorylase FP0431 204 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 150024965 Common - hypothetical protein FP0875 71 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 150024522 Common map Methionine aminopeptidase FP0419 247 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 150025661 Pathogen - hypothetical protein FP1611 1 None None None 150026220 Pathogen - hypothetical protein FP2184 1 None None None 150025403 Common rpsS 30S ribosomal protein S19 FP1335 246 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 150026480 Common - Probable transmembrane protein FP2452 67 COG3182 PiuB, Uncharacterized iron-regulated membrane protein Function unknown 150024615 Common - Rhodanese-related sulfurtransferase FP0517 87 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 150026103 Common mraZ Protein MraZ FP2065 127 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 150026431 Common - Probable membrane fusion efflux protein precursor FP2402 174 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150024405 Common yggG Putative M48 family metalloprotease YggG FP0300 101 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 150025273 Common - Putative muramidase FP1205 63 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 150026186 Common - Probable type II restriction endonuclease FP2149 9 None None None 150025009 Common - Probable transcriptional regulator, TetR family FP0924 29 COG1309 AcrR, Transcriptional regulator Transcription 150025628 Common - hypothetical protein FP1577 72 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 150025070 Pathogen - hypothetical protein FP0989 1 None None None 150026167 Common - hypothetical protein FP2129 2 None None None 150026398 Common pop Prolyl oligopeptidase family protein FP2368 112 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 150024340 Common pth peptidyl-tRNA hydrolase FP0230 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 150026460 Pathogen - hypothetical protein FP2431 1 None None None 150024248 Common - ATPase, MoxR family FP0136 174 COG0714 COG0714, MoxR-like ATPases General function prediction only 150026142 Pathogen - hypothetical protein FP2104 2 None None None 150025675 Common pabB Para-aminobenzoate synthase component I FP1625 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 150024347 Common rbfA Ribosome-binding factor A FP0238 69 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 150024994 Common - hypothetical protein FP0909 2 None None None 150025547 Common - hypothetical protein FP1491 43 COG3829 RocR, Transcriptional regulator containing PAS, AAA-type ATPase, and DNA-binding domains Transcription / Signal transduction mechanisms 150025590 Common - hypothetical protein FP1539 4 None None None 150025887 Pathogen - hypothetical protein FP1844 1 None None None 150025719 Common - NifU-like protein FP1669 93 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 150025419 Common - Probable hydrolase (HAD superfamily) FP1351 96 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 150025811 Common - Probable S8 subtilisin family serine endopeptidase precursor FP1763 84 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 150025242 Common - hypothetical protein FP1170 5 None None None 150025032 Common - Acyl-CoA hydrolase family protein FP0950 44 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 150025821 Common - Probable chloride channel protein FP1773 163 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 150026515 Pathogen - hypothetical protein FP2487 1 None None None 150025643 Common dgkA Diacylglycerol kinase FP1593 75 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 150025412 Common - Probable outer membrane protein precursor FP1344 3 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 150025124 Pathogen - hypothetical protein FP1045 1 None None None 150024975 Common panB1 3-methyl-2-oxobutanoate hydroxymethyltransferase panB1 FP0885 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 150026330 Common gspE Putative bacterial general secretion pathway protein E FP2300 164 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 150024828 Common - Putative DNA binding protein FP0735 2 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 150024989 Pathogen - hypothetical protein FP0904 1 None None None 150025971 Common pepD Xaa-His dipeptidase FP1929 62 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 150025123 Common - hypothetical protein FP1044 103 COG1964 COG1964, Predicted Fe-S oxidoreductases General function prediction only 150024175 Common - Flagellar motor/Chemotaxis (MotB)-related protein FP0061 134 COG1360 MotB, Flagellar motor protein Cell motility and secretion 150025611 Common - hypothetical protein FP1560 7 None None None 150024908 Pathogen - hypothetical protein FP0818 1 None None None 150024375 Common - hypothetical protein FP0267 10 None None None 150025601 Common - hypothetical protein FP1550 2 None None None 150024462 Common - Probable TonB-dependent outer membrane receptorprecursor FP0357 26 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150025310 Common - hypothetical protein FP1242 8 None None None 150024452 Common gcdH Glutaryl-CoA dehydrogenase FP0347 159 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 150024256 Common - Probable TonB-dependent outer membrane receptorprecursor FP0144 69 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 150026439 Common - Major facilitator superfamily (MFS) permease FP2410 100 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150025393 Common rpsH 30S ribosomal protein S8 FP1325 245 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 150025656 Common fumC fumarate hydratase FP1606 229 COG0114 FumC, Fumarase Energy production and conversion 150024139 Common mrcA Penicillin-binding protein 1A FP0025 201 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 150025910 Common - Probable tRNA/rRNA methyltransferase FP1867 205 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 150025908 Common wbsE Putative glycosyl transferase WbsE FP1865 3 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150024354 Common dinD DNA-damage-inducible protein D FP0245 20 None None None 150024775 Common glyA serine hydroxymethyltransferase FP0681 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 150025249 Common rplL 50S ribosomal protein L7/L12 FP1177 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 150025359 Common - Probable polysaccharide export protein FP1291 27 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 150026212 Pathogen - hypothetical protein FP2176 1 None None None 150024235 Common - hypothetical protein FP0123 3 None None None 150024230 Pathogen - hypothetical protein FP0118 1 None None None 150025516 Common bluB/cobT Bifunctional protein : cob(II)yrinic acid a,c-diamide reductase and nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase FP1460 124 COG2038 CobT, NaMN:DMB phosphoribosyltransferase Coenzyme metabolism 150024274 Common pyrC1 dihydroorotase FP0164 210 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 150024556 Common tsf Elongation factor Ts (EF-Ts) FP0453 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 150024336 Common hppD 4-hydroxyphenylpyruvate dioxygenase FP0226 77 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 150025565 Common htpG heat shock protein 90 FP1509 147 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 150025335 Common neuD Protein of unknown function NeuD FP1267 74 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 150026060 Common hisS histidyl-tRNA synthetase FP2021 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150025044 Common - Probable phosphoglycerol transferase FP0962 63 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 150024562 Common - hypothetical protein FP0459 9 None None None 150024475 Common ogt2 Methylated-DNA--[protein]-cysteineS-methyltransf erase FP0370 105 COG3695 COG3695, Predicted methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 150024793 Common - hypothetical protein FP0700 7 None None None 150025021 Common - Glycosyl transferase, group 1 family protein FP0939 40 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150024574 Common typA GTP-binding protein TypA FP0476 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 150024546 Common - Acetyltransferase, GNAT family FP0443 14 COG0456 RimI, Acetyltransferases General function prediction only 150024144 Common atoA 3-oxoacid CoA-transferase subunit B family protein AtoA FP0030 98 COG2057 AtoA, Acyl CoA:acetate/3-ketoacid CoA transferase, beta subunit Lipid metabolism 150025589 Common - hypothetical protein FP1538 4 None None None 150026280 Common rpoN RNA polymerase sigma-54 factor RpoN FP2249 145 COG1508 RpoN, DNA-directed RNA polymerase specialized sigma subunit, sigma54 homolog Transcription 150026475 Common - hypothetical protein FP2447 4 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 150025146 Common - hypothetical protein FP1067 203 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 150024594 Common - hypothetical protein FP0496 2 None None None 150025939 Common osmC Putative stress-induced protein OsmC FP1897 12 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 150024366 Common metY Probable O-acetylhomoserine aminocarboxypropyltransferase FP0257 206 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 150025728 Common - hypothetical protein FP1680 3 None None None 150026287 Common - Probable bifunctional protein : exporter and 1-acyl-sn-glycerol-3-phosphate acyltransferase precursor FP2256 122 COG4258 COG4258, Predicted exporter General function prediction only 150025471 Common - Probable sugar O-acetyltransferase precursor FP1412 5 None None None 150025551 Common - Probable TonB-dependent outer membrane receptorprecursor FP1495 123 COG4771 FepA, Outer membrane receptor for ferrienterochelin and colicins Inorganic ion transport and metabolism 150024427 Common accD Acetyl-coenzyme A carboxylase carboxyl transferase beta subunit FP0322 218 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 150025037 Common hisA 1-(5-phosphoribosyl)-5-((5-phosphoribosylamino)methylideneamino)imidazole-4-carboxamide isomerase FP0955 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 150025891 Common - hypothetical protein FP1848 3 None None None 150026121 Common - Putative Sec-independent protein translocase (twin-arginine translocation protein) FP2083 54 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 150024652 Pathogen - hypothetical protein FP0557 1 None None None 150025876 Common - 5'-nucleotidase FP1833 137 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 150024443 Common - Putative outer membrane protein FP0338 6 None None None 150024490 Pathogen - hypothetical protein FP0385 1 None None None 150026245 Common speB Agmatinase FP2214 130 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 150026273 Common lepA GTP-binding protein LepA FP2242 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 150024861 Common yuxK Protein of unknown function YuxK FP0768 34 COG3011 COG3011, Uncharacterized protein conserved in bacteria Function unknown 150025029 Common - hypothetical protein FP0947 3 None None None 150024685 Common bfmBB Dihydrolipoyllysine-residue(2-methylpropanoyl)tr ansferase FP0590 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 150025672 Common - hypothetical protein FP1622 1 None None None 150024397 Common - hypothetical protein FP0291 95 COG1408 COG1408, Predicted phosphohydrolases General function prediction only 150024766 Common - Probable nucleoside-diphosphate sugar epimerase FP0672 111 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 150026303 Common - Probable ABC-type transport system, ATPase component FP2272 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150024158 Common hemA Glutamyl-tRNA reductase FP0044 181 COG0373 HemA, Glutamyl-tRNA reductase Coenzyme metabolism 150026497 Common - Probable heptosyltransferase involved in lipopolysaccharide core biosynthesis FP2469 66 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 150024636 Common - Probable ABC-type transport system, binding protein precursor component FP0538 108 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 150025053 Common sucD Succinyl-CoA synthetase, alpha subunit FP0972 210 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 150026328 Common - Putative bacterial general secretion pathway protein FP2298 1 None None None 150024818 Common murQ N-acetylmuramic acid-6-phosphate etherase FP0725 83 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 150024518 Common pruA 1-pyrroline-5-carboxylate dehydrogenase FP0415 218 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150024468 Common pstA ABC-type phosphate-transport system, permease component PstA FP0363 228 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 150024576 Common menB Naphthoate synthase FP0478 177 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 150026306 Common - hypothetical protein FP2275 14 None None None 150025655 Pathogen - hypothetical protein FP1605 1 None None None 150025469 Common - hypothetical protein FP1410 4 None None None 150024868 Pathogen - hypothetical protein FP0778 1 None None None 150026504 Common wcaJ Putative colanic biosynthesis UDP-glucose lipidcarrier transferase FP2476 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 150026013 Common gldK Gliding motility protein GldK FP1973 89 COG1262 COG1262, Uncharacterized conserved protein Function unknown 150026299 Common - hypothetical protein FP2268 4 None None None 150024516 Common - Fatty acid desaturase FP0413 38 COG3239 DesA, Fatty acid desaturase Lipid metabolism 150026285 Common - hypothetical protein FP2254 14 COG4927 COG4927, Predicted choloylglycine hydrolase General function prediction only 150025105 Common - Fumarylacetoacetate hydrolase family protein FP1026 172 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 150025046 Common - 3-oxoacyl-[acyl-carrier-protein] reductase FP0964 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150024191 Common sirR Probable metal-dependent transcriptional regulator FP0077 87 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 150025894 Common rpsF 30S ribosomal protein S6 FP1851 183 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 150024386 Common - hypothetical protein FP0278 2 None None None 150024238 Common - Probable transmembrane protein FP0126 20 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 150025035 Common hisIE Histidine biosynthesis bifunctional protein HisIE [Includes: Phosphoribosyl-AMP cyclohydrolase; Phosphoribosyl-ATP pyrophosphatase] FP0953 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 150024779 Common purM Phosphoribosylformylglycinamidine cyclo-ligase FP0685 218 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 150024509 Common galE UDP-glucose 4-epimerase FP0406 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 150024478 Common hmoA Probable molybdopterin oxidoreductase, iron-sulfur binding subunit FP0373 116 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 150024164 Common - Probable hydrolase FP0050 60 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 150026335 Common - hypothetical protein FP2305 2 None None None 150025473 Common - hypothetical protein FP1414 9 None None None 150024526 Pathogen - Probable transcriptional regulator, TetR family FP0423 1 COG1309 AcrR, Transcriptional regulator Transcription 150025670 Common - Putative transporting permease FP1620 186 COG0628 PerM, Predicted permease General function prediction only 150025748 Common - hypothetical protein FP1700 8 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 150025494 Common - Probable exopolyphosphatase FP1435 10 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 150024694 Common - hypothetical protein FP0599 184 COG0759 COG0759, Uncharacterized conserved protein Function unknown 150024929 Common - Putative spermidine synthase FP0839 16 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 150025552 Common - hypothetical protein FP1496 6 None None None 150024145 Common - Probable transmembrane protein of unknown function FP0031 39 COG2715 SpmA, Uncharacterized membrane protein, required for spore maturation in B.subtilis. General function prediction only 150025022 Common - Putative capsular polysaccharide biosynthesis protein FP0940 9 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 150024445 Common - Putative carboxypeptidase FP0340 66 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 150024184 Common - hypothetical protein FP0070 6 None None None 150024917 Pathogen - hypothetical protein FP0827 1 None None None 150024541 Common - Major facilitator superfamily (MFS) permease FP0438 44 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150026371 Common - Probable hydroxymethylglutaryl-coenzyme A reductase FP2341 37 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 150024142 Pathogen - hypothetical protein FP0028 1 None None None 150024897 Pathogen - hypothetical protein FP0807 2 None None None 150024135 Common - Probable outer membrane protein, OmpA family FP0021 56 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 150025041 Common hisD Histidinol dehydrogenase FP0959 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 150025623 Common - hypothetical protein FP1572 4 None None None 150025713 Common gldD Gliding motility protein GldD FP1663 4 None None None 150024255 Common nadD nicotinic acid mononucleotide adenyltransferase FP0143 188 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 150025909 Common relA GTP diphosphokinase FP1866 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 150024552 Common ilvD dihydroxy-acid dehydratase FP0449 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 150024568 Common - hypothetical protein FP0465 7 None None None 150024393 Common - hypothetical protein FP0287 1 None None None 150025536 Common - Protein of unknown function containing ankyrin repeat signature FP1480 67 COG0666 Arp, FOG: Ankyrin repeat General function prediction only 150026517 Common rnr Ribonuclease R FP2489 192 COG0557 VacB, Exoribonuclease R Transcription 150024598 Common - hypothetical protein FP0500 3 None None None 150024500 Common - Probable tRNA/rRNA methyltransferase FP0397 204 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 150025535 Pathogen - hypothetical protein FP1479 1 None None None 150025349 Common - Probable nucleoside-diphosphate-sugar epimerase FP1281 55 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150024668 Common fsr Major facilitator superfamily (MFS) permease. Fosmidomycin resistance protein FP0573 103 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150025644 Common tpx Thiol peroxidase FP1594 129 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150026181 Pathogen - hypothetical protein FP2144 1 None None None 150026380 Common - hypothetical protein FP2350 90 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 150025319 Common - Glycosyl transferase, group 2 family protein FP1251 10 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 150025607 Common - hypothetical protein FP1556 5 None None None 150025903 Common yydA hypothetical protein FP1860 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 150025528 Common deoD purine nucleoside phosphorylase FP1472 154 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 150024453 Common gmk Guanylate kinase FP0348 212 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 150025391 Common rplR 50S ribosomal protein L18 FP1323 215 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 150026062 Common hemK Methylase of polypeptide chain release factors FP2023 222 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 150025630 Common - Putative thioesterase FP1579 5 COG0824 FcbC, Predicted thioesterase General function prediction only 150024280 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0170 14 None None None 150026222 Common - Protein of unknown function, putative esterase/lipase/thioesterase FP2186 3 None None None 150024245 Common - hypothetical protein FP0133 6 None None None 150024272 Common - hypothetical protein FP0162 83 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150024875 Pathogen - hypothetical protein FP0785 2 None None None 150024215 Pathogen - hypothetical protein FP0103 1 None None None 150025428 Common hpt Hypoxanthine phosphoribosyltransferase FP1360 151 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 150024684 Common - Glycosyl transferase, group 2 family protein FP0589 175 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 150025126 Common - hypothetical protein FP1047 3 None None None 150024682 Common - hypothetical protein FP0587 13 None None None 150024356 Common dtd D-tyrosyl-tRNA(Tyr) deacylase FP0247 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 150024954 Common dnaK Chaperone protein DnaK FP0864 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 150024689 Pathogen - hypothetical protein FP0594 1 None None None 150025935 Common - hypothetical protein FP1893 76 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 150025967 Common - Glu/Leu/Phe/Val dehydrogenase family protein FP1925 159 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 150025653 Common - Probable arsenate reductase (glutaredoxin) FP1603 106 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 150026355 Common pcd Piperideine-6-carboxylate dehydrogenase FP2325 218 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150025464 Common - Probable two-component system sensor histidine kinase FP1405 218 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150025245 Pathogen - hypothetical protein FP1173 1 None None None 150026432 Common - Probable outer membrane efflux protein precursor FP2403 47 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150026094 Common murC UDP-N-acetylmuramate--L-alanine ligase FP2056 210 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 150024782 Common - Protein of unknown function; putative adhesin FP0688 10 COG5295 Hia, Autotransporter adhesin Intracellular trafficking and secretion / Extracellular structures 150026141 Common yyaL Protein of unknown function YyaL FP2103 105 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 150025276 Common dnaA Chromosomal replication initiator protein DnaA FP1208 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 150025320 Common - Glycosyl transferase, group 1 family protein FP1252 200 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150025593 Pathogen - hypothetical protein FP1542 1 None None None 150025418 Common - hypothetical protein FP1350 2 None None None 150025784 Common sodC Superoxide dismutase [Cu-Zn] FP1736 85 COG2032 SodC, Cu/Zn superoxide dismutase Inorganic ion transport and metabolism 150025769 Common ggt Gamma-glutamyltransferase FP1721 148 COG0405 Ggt, Gamma-glutamyltransferase Amino acid transport and metabolism 150025614 Pathogen - hypothetical protein FP1563 1 None None None 150026272 Pathogen - hypothetical protein FP2241 1 None None None 150024808 Common - Probable two-component system response regulatory protein FP0715 217 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150025411 Common rpsL 30S ribosomal protein S12 FP1343 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 150024332 Common uvrC Excinuclease ABC, C subunit FP0222 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 150025226 Common ccoS Probable cytochrome cbb3 oxidase maturation protein CcoS FP1154 2 COG3197 FixS, Uncharacterized protein, possibly involved in nitrogen fixation Inorganic ion transport and metabolism 150024925 Common - hypothetical protein FP0835 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 150026346 Pathogen - hypothetical protein FP2316 1 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 150025476 Common bsaA Glutathione peroxidase BsaA FP1417 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 150024537 Common thiF Molybdopterin and thiamine biosynthesis protein FP0434 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 150025521 Common - Glycosyl transferase, group 2 family protein FP1465 124 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150024440 Common etfA Electron transfer flavoprotein, alpha subunit FP0335 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 150026162 Common - Putative 4Fe-4S binding protein FP2124 133 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 150024848 Common - hypothetical protein FP0755 2 None None None 150026461 Common - hypothetical protein FP2432 4 None None None 150024661 Common - hypothetical protein FP0566 127 COG2326 COG2326, Uncharacterized conserved protein Function unknown 150025058 Common lpxC/fabZ bifunctional UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase/(3R)-hydroxymyristoyl-[acyl-carrier-protein] dehydratase FP0977 191 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 150024435 Common - hypothetical protein FP0330 14 None None None 150025996 Common phhA phenylalanine 4-monooxygenase FP1954 45 COG3186 COG3186, Phenylalanine-4-hydroxylase Amino acid transport and metabolism 150025602 Pathogen - hypothetical protein FP1551 1 None None None 150024910 Pathogen - hypothetical protein FP0820 1 None None None 150024131 Common - hypothetical protein FP0017 4 None None None 150026491 Common - RCC1 (Regulator of Chromosome Condensation) repeat domain protein FP2463 42 COG5184 ATS1, Alpha-tubulin suppressor and related RCC1 domain-containing proteins Cell division and chromosome partitioning / Cytoskeleton 150024426 Common - Probable outer membrane protein, OmpA family FP0321 126 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 150026192 Common - hypothetical protein FP2155 2 None None None 150024747 Common - hypothetical protein FP0652 11 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 150025662 Common - hypothetical protein FP1612 6 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 150024151 Common hemF coproporphyrinogen III oxidase FP0037 113 COG0408 HemF, Coproporphyrinogen III oxidase Coenzyme metabolism 150026315 Common fabB 3-oxoacyl-(acyl-carrier-protein) synthase I FP2284 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150025362 Common rmlB dTDP-glucose 4,6-dehydratase FP1294 233 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 150026149 Common - Probable cytochrome c oxidase biogenesis protein FP2111 66 COG1999 COG1999, Uncharacterized protein SCO1/SenC/PrrC, involved in biogenesis of respiratory and photosynthetic systems General function prediction only 150025408 Common rpsJ 30S ribosomal protein S10 FP1340 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 150025557 Common fabH2 3-oxoacyl-[acyl-carrier-protein] synthase III protein FabH2 FP1501 212 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 150026113 Common - hypothetical protein FP2075 2 None None None 150025277 Common - Low molecular weight phosphotyrosine protein phosphatase FP1209 136 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 150025609 Pathogen - hypothetical protein FP1558 1 None None None 150025757 Common - hypothetical protein FP1709 38 COG1899 DYS1, Deoxyhypusine synthase Posttranslational modification, protein turnover, chaperones 150025941 Common pyrG CTP synthetase FP1899 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 150024991 Common - hypothetical protein FP0906 31 COG4807 COG4807, Uncharacterized protein conserved in bacteria Function unknown 150024228 Common - hypothetical protein FP0116 1 None None None 150024391 Common - hypothetical protein FP0285 1 None None None 150024890 Common ibrA Protein of unknown function IbrA FP0800 24 COG3969 COG3969, Predicted phosphoadenosine phosphosulfate sulfotransferase General function prediction only 150026086 Common - hypothetical protein FP2047 1 None None None 150024381 Common - hypothetical protein FP0273 9 None None None 150024283 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0173 22 None None None 150025506 Common crtB Geranylgeranyl-diphosphategeranylgeranyltransfera se FP1450 80 COG1562 ERG9, Phytoene/squalene synthetase Lipid metabolism 150024320 Common - hypothetical protein FP0210 2 None None None 150025664 Common pfkA 6-phosphofructokinase FP1614 158 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 150025376 Common gltA Citrate (Si)-synthase FP1308 194 COG0372 GltA, Citrate synthase Energy production and conversion 150025676 Common tilS tRNA(Ile)-lysidine synthase FP1626 182 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 150024289 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0179 20 None None None 150024996 Common - hypothetical protein FP0911 4 None None None 150026465 Common smf Protein Smf of unknown function FP2437 211 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 150025820 Common - hypothetical protein FP1772 10 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 150025176 Common - Major facilitator superfamily (MFS) permease FP1103 31 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150024343 Common ribF Bifunctional riboflavin biosynthesis protein RibF : Riboflavin kinase and FMN adenylyltransferase FP0233 211 COG0196 RibF, FAD synthase Coenzyme metabolism 150026120 Common - Probable membrane-associated phospholipid phosphatase FP2082 21 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 150025383 Common rpsK 30S ribosomal protein S11 FP1315 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 150026471 Common - Esterase/lipase/thioesterase family protein FP2443 22 COG2267 PldB, Lysophospholipase Lipid metabolism 150025401 Common rpsC 30S ribosomal protein S3 FP1333 248 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 150026393 Common leuS leucyl-tRNA synthetase FP2363 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150025884 Common recN DNA repair protein recN FP1841 204 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 150026357 Common - 3-oxoacyl-(acyl-carrier-protein) synthase FP2327 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150024611 Common trpE Anthranilate synthase component I FP0513 222 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 150024461 Common - Probable lipoprotein precursor FP0356 23 None None None 150024803 Common - Probable two-component system sensor histidine kinase FP0710 116 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 150026218 Common - Probable penicillin-binding protein FP2182 135 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 150025327 Common - hypothetical protein FP1259 2 None None None 150025199 Common lepB Signal peptidase I FP1127 163 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 150025212 Common - hypothetical protein FP1140 11 None None None 150024363 Pathogen - hypothetical protein FP0254 1 None None None 150026039 Common - hypothetical protein FP1999 34 COG5587 COG5587, Uncharacterized conserved protein Function unknown 150025144 Common mscL Large-conductance mechanosensitive channel FP1065 121 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 150026404 Common - hypothetical protein FP2374 52 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 150025793 Common - Putative dinucleotide-utilizing enzyme involvedin molybdopterin and thiamine biosynthesis FP1745 195 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 150026029 Common irk Inward rectifier potassium channel Irk FP1989 17 None None None 150025486 Common tlpB Putative thiol:disulfide oxidoreductase TlpB FP1427 2 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 150024805 Pathogen - hypothetical protein FP0712 1 None None None 150026447 Common mreC Rod shape-determining protein MreC FP2418 123 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 150025238 Common - ATPase, MoxR family FP1166 190 COG0714 COG0714, MoxR-like ATPases General function prediction only 150024169 Common metG methionyl-tRNA synthetase FP0055 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150025726 Common prmA ribosomal protein L11 methyltransferase FP1678 158 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 150024315 Common - hypothetical protein FP0205 3 None None None 150025251 Common rplA 50S ribosomal protein L1 FP1179 220 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 150025306 Common yegX Protein of unknown function YegX FP1238 42 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 150025180 Common uvrA1 Excinuclease ABC, A subunit UvrA1 FP1107 231 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 150024765 Common grpE Chaperone protein GrpE FP0671 221 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 150025229 Pathogen ccoQ Cytochrome c oxidase, cbb3-type, subunit IV FP1157 1 None None None 150026262 Common nuoB NADH dehydrogenase I, B subunit FP2231 192 COG0377 NuoB, NADH:ubiquinone oxidoreductase 20 kD subunit and related Fe-S oxidoreductases Energy production and conversion 150026348 Pathogen - hypothetical protein FP2318 1 None None None 150024409 Common - hypothetical protein FP0304 1 None None None 150025086 Common - hypothetical protein FP1007 8 None None None 150025163 Common gldG Gliding motility protein GldG FP1090 13 COG3225 GldG, ABC-type uncharacterized transport system involved in gliding motility, auxiliary component Cell motility and secretion 150026243 Common kmo Kynurenine 3-monooxygenase FP2212 67 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 150025451 Common pdhA Pyruvate dehydrogenase E1 component, alpha subunit FP1385 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 150025184 Common cphA Cyanophycin synthetase FP1111 84 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 150026203 Common - Probable type III restriction enzyme FP2167 33 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 150026331 Pathogen - Putative bacterial general secretion pathway protein FP2301 1 None None None 150025231 Common ccoG Probable cytochrome cbb3 oxidase maturation protein CcoG FP1159 98 COG0348 NapH, Polyferredoxin Energy production and conversion 150025342 Common - Probable capsular polysaccharide biosynthesis protein FP1274 39 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 150024650 Pathogen - hypothetical protein FP0553 1 None None None 150026092 Common ftsA Cell division protein FtsA FP2054 196 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 150025866 Common mvaB Hydroxymethylglutaryl-CoA lyase FP1821 97 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 150026301 Common - Probable esterase FP2270 73 COG0824 FcbC, Predicted thioesterase General function prediction only 150025893 Common rpsR 30S ribosomal protein S18 FP1850 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 150025007 Common lolC Lipoprotein releasing system transmembrane protein LolC FP0922 170 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150025209 Common - Glycosyl transferase, group 2 family protein FP1137 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150026443 Common hflX GTP-binding protein HflX FP2414 225 COG2262 HflX, GTPases General function prediction only 150025931 Common - hypothetical protein FP1889 2 None None None 150026042 Common - hypothetical protein FP2002 8 None None None 150024481 Common - Cytochrome c family protein FP0376 23 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 150025952 Common - Oxidoreductase, Gfo/Idh/MocA family FP1910 167 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 150025786 Common oxyR Redox-sensitive transcriptional activator OxyR FP1738 187 COG0583 LysR, Transcriptional regulator Transcription 150024584 Common - hypothetical protein FP0486 7 None None None 150026214 Pathogen - Probable phage protein FP2178 1 None None None 150024749 Common coaD Pantetheine-phosphate adenylyltransferase FP0654 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 150025178 Common - Putative sensor (PAS) domain for methyl-accepting chemotaxis sensory transducer FP1105 82 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 150024128 Common sprC Putative adhesin precursor SprC FP0014 6 None None None 150025685 Pathogen - hypothetical protein FP1635 4 None None None 150025267 Common - Probable outer membrane protein, Omp121 family FP1199 29 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 150026350 Common - hypothetical protein FP2320 2 None None None 150026061 Common - Probable ABC-type transport system, permease component FP2022 155 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 150026482 Common - Putative siderophore biosynthesis protein FP2454 46 COG4264 RhbC, Siderophore synthetase component Secondary metabolites biosynthesis, transport, and catabolism 150026236 Common - hypothetical protein FP2205 35 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 150024973 Common - Probable phosphoglycerol transferase FP0883 68 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 150024214 Common - hypothetical protein FP0102 9 None None None 150025333 Common - Glycosyl transferase, group 1 family protein FP1265 5 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150025068 Pathogen - hypothetical protein FP0987 2 None None None 150026151 Common - hypothetical protein FP2113 3 None None None 150025679 Common - hypothetical protein FP1629 2 None None None 150024943 Common - hypothetical protein FP0853 33 COG3124 COG3124, Uncharacterized protein conserved in bacteria Function unknown 150025960 Pathogen - hypothetical protein FP1918 2 None None None 150024121 Common - Probable helicase FP0007 31 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 150026030 Common - Acyl-CoA hydrolase family protein FP1990 133 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 150026250 Common nuoM NADH dehydrogenase I, M subunit FP2219 210 COG1008 NuoM, NADH:ubiquinone oxidoreductase subunit 4 (chain M) Energy production and conversion 150026259 Common nuoE NADH dehydrogenase I, E subunit FP2228 156 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 150026152 Common - hypothetical protein FP2114 5 None None None 150025692 Common - Glycosyl transferase, group 2 family protein FP1642 202 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150026158 Common gcvH Glycine cleavage system H protein FP2120 186 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 150026522 Common - hypothetical protein FP2495 1 None None None 150025115 Common - hypothetical protein FP1036 4 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 150024729 Common folE1 GTP cyclohydrolase I FP0634 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 150025911 Common - hypothetical protein FP1868 133 COG2860 COG2860, Predicted membrane protein Function unknown 150026084 Common rpsO 30S ribosomal protein S15 FP2045 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 150024225 Common - Probable outer membrane protein FP0113 6 None None None 150026385 Common - hypothetical protein FP2355 11 None None None 150025133 Common - hypothetical protein FP1054 12 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 150025598 Common - hypothetical protein FP1547 2 None None None 150026407 Common accC Biotin carboxylase FP2377 234 COG4770 COG4770, Acetyl/propionyl-CoA carboxylase, alpha subunit Lipid metabolism 150026007 Common - Probably involved in regulation of translation initiation FP1967 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150026226 Common - Probable ABC-type transport system, permease component FP2195 96 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150026071 Common - hypothetical protein FP2032 4 None None None 150025803 Common mazG nucleoside triphosphate pyrophosphohydrolase FP1755 155 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 150025847 Common yghO Protein of unknown function YghO FP1802 39 None None None 150024570 Common uspA Universal stress protein UspA FP0467 148 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 150025562 Common - hypothetical protein FP1506 3 None None None 150025988 Common - Protein of unknown function precursor FP1946 81 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 150025779 Common - Esterase/lipase/thioesterase family protein FP1731 3 COG1075 LipA, Predicted acetyltransferases and hydrolases with the alpha/beta hydrolase fold General function prediction only 150025937 Common - hypothetical protein FP1895 39 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 150024711 Common - Protein of unknown function; putative adhesin FP0616 2 None None None 150025499 Common - Probable ribosome-associated heat shock proteinHsp15 FP1440 96 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 150026078 Common - hypothetical protein FP2039 2 None None None 150024704 Common - hypothetical protein FP0609 9 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150026118 Common yloN Protein of unknown function YloN FP2080 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 150024841 Common gyrA DNA gyrase subunit A FP0748 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 150025708 Common - hypothetical protein FP1658 6 None None None 150025317 Common - Probable methyltransferase FP1249 12 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 150024579 Common - Putative monofunctional lysine-ketoglutarate reductase FP0481 11 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 150024937 Common - hypothetical protein FP0847 3 COG1700 COG1700, Uncharacterized conserved protein Function unknown 150026054 Common - Probable membrane-bound lytic murein transglycosylase precursor FP2015 110 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 150024621 Common - hypothetical protein FP0523 1 None None None 150024596 Common menC O-succinylbenzoate synthase FP0498 73 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 150025582 Common - hypothetical protein FP1531 8 None None None 150024733 Common - hypothetical protein FP0638 3 COG5403 COG5403, Uncharacterized conserved protein Function unknown 150024492 Common - hypothetical protein FP0387 52 COG3378 COG3378, Predicted ATPase General function prediction only 150025772 Common - hypothetical protein FP1724 33 None None None 150024788 Common purL phosphoribosylformylglycinamidine synthase FP0695 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 150024412 Pathogen - hypothetical protein FP0307 1 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 150024638 Common folC Bifunctional protein : Folylpolyglutamate synthase and Dihydrofolate synthase FP0541 219 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 150025576 Common - Probable CRISPR-associated (Cas) protein. Cas1 family FP1525 39 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 150026434 Common - Polyprenyl synthetase FP2405 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 150025500 Common - hypothetical protein FP1441 22 None None None 150024920 Pathogen - hypothetical protein FP0830 1 None None None 150026011 Common gldM Gliding motility protein GldM FP1971 6 None None None 150024325 Pathogen - hypothetical protein FP0215 1 None None None 150025621 Common - hypothetical protein FP1570 3 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 150025981 Pathogen - hypothetical protein FP1939 1 None None None 150025466 Common - hypothetical protein FP1407 55 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 150024115 Common - Putative chromosome segregation ATPase FP0001 5 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 150025458 Common rpsT 30S ribosomal protein S20 FP1397 114 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 150025959 Pathogen - hypothetical protein FP1917 1 None None None 150025079 Common - Phosphate transporter family protein FP1000 142 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 150025632 Common - Putative ATP/GTP-binding protein FP1581 5 None None None 150026511 Common - hypothetical protein FP2483 4 None None None 150024816 Common - hypothetical protein FP0723 2 None None None 150024177 Common - Putative hemolysin FP0063 41 COG3176 COG3176, Putative hemolysin General function prediction only 150024497 Common - hypothetical protein FP0392 14 COG5635 COG5635, Predicted NTPase (NACHT family) Signal transduction mechanisms 150024241 Common batC BatC protein FP0129 12 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 150024985 Common thrS Threonine--tRNA ligase FP0895 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150025014 Common - Probable multidrug resistance protein precursor. AcrB/AcrD/AcrF family protein FP0932 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150025948 Common - Probable sugar O-acetyltransferase precursor FP1906 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 150026429 Common - Probable ferredoxin FP2399 48 COG0633 Fdx, Ferredoxin Energy production and conversion 150025853 Common - hypothetical protein FP1808 14 None None None 150024770 Common - hypothetical protein FP0676 8 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 150024889 Pathogen - Probable transcriptional regulator, XRE family FP0799 1 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 150024425 Common - hypothetical protein FP0320 5 None None None 150025421 Common - Mur ligase family protein FP1353 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 150026219 Common - hypothetical protein FP2183 2 None None None 150025973 Common ndh NADH dehydrogenase FP1931 172 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 150024777 Common tktC Transketolase, C-terminal subunit FP0683 229 COG3958 COG3958, Transketolase, C-terminal subunit Carbohydrate transport and metabolism 150024624 Common asnB asparagine synthetase B FP0526 174 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 150026374 Pathogen - hypothetical protein FP2344 1 None None None 150026173 Common - Integrase/recombinase FP2136 229 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 150026111 Common - hypothetical protein FP2073 24 None None None 150024646 Common - Protein of unknown function; putative anti ECF-type sigma factor FP0549 5 None None None 150024266 Common - Outer membrane protein OmpA family P60 FP0156 170 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 150024678 Common - hypothetical protein FP0583 131 COG2096 COG2096, Uncharacterized conserved protein Function unknown 150024209 Pathogen - hypothetical protein FP0096 1 None None None 150025299 Pathogen - hypothetical protein FP1231 1 None None None 150025619 Common - Putative DNA binding protein FP1568 3 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 150025449 Common - Probable short-chain type dehydrogenase FP1383 237 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 150026365 Common - Thioredoxin family protein FP2335 6 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 150024603 Common - Probable transcriptional regulator, TetR family FP0505 126 COG1309 AcrR, Transcriptional regulator Transcription 150025442 Common - Glycosyl transferase, group 2 family protein FP1376 156 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 150024739 Common engD translation-associated GTPase FP0644 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 150026123 Common clpP S14 family, ATP-dependent Clp protease proteolytic subunit FP2085 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150025343 Common - Probable tyrosine-protein kinase involved in exopolysaccharide biosynthesis FP1275 152 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150025605 Common - hypothetical protein FP1554 10 None None None 150026489 Common atpE ATP synthase C subunit FP2461 44 None None None 150024182 Common ksgA dimethyladenosine transferase FP0068 247 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 150024740 Common - Probable TonB-dependent outer membrane siderophore receptor precursor FP0645 97 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150024279 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0169 17 None None None 150025518 Common - hypothetical protein FP1462 5 None None None 150024978 Common aldH Aldehyde dehydrogenase FP0888 220 COG1012 PutA, NAD-dependent aldehyde dehydrogenases Energy production and conversion 150026075 Common - hypothetical protein FP2036 4 None None None 150025696 Common - CDP-alcohol phosphatidyltransferase class-I family protein FP1646 10 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 150024699 Common - hypothetical protein FP0604 3 None None None 150025538 Common - hypothetical protein FP1482 36 COG4447 COG4447, Uncharacterized protein related to plant photosystem II stability/assembly factor General function prediction only 150024334 Common - Probable amino acid-transporting permease FP0224 186 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150025511 Common - RNA polymerase ECF-type sigma factor FP1455 88 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150026048 Common fmt methionyl-tRNA formyltransferase FP2009 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 150024243 Common - hypothetical protein FP0131 17 None None None 150025646 Common - hypothetical protein FP1596 3 None None None 150026041 Common recF DNA replication and repair protein RecF FP2001 164 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 150025881 Common - hypothetical protein FP1838 7 None None None 150025933 Common ppiA Probable peptidyl-prolyl cis-trans isomerase PpiA FP1891 203 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 150025512 Common - Probable lipoprotein precursor FP1456 6 None None None 150024933 Common - Probable transcriptional regulator, AsnC family FP0843 153 COG1522 Lrp, Transcriptional regulators Transcription 150025462 Common - hypothetical protein FP1403 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 150026435 Common - hypothetical protein FP2406 1 None None None 150024873 Pathogen - hypothetical protein FP0783 1 None None None 150025616 Pathogen - hypothetical protein FP1565 1 None None None 150025543 Common irpA Iron-regulated protein A precursor FP1487 9 COG3489 COG3489, Predicted periplasmic lipoprotein General function prediction only 150025838 Common rpsA 30S ribosomal protein S1 FP1793 215 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 150024270 Common sodA Superoxide dismutase [Mn] FP0160 206 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 150024455 Common - hypothetical protein FP0350 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 150026064 Common ribD Riboflavin biosynthesis protein RibD FP2025 219 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 150026018 Common - hypothetical protein FP1978 2 None None None 150024680 Common - hypothetical protein FP0585 7 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 150026171 Common - hypothetical protein FP2134 25 None None None 150024117 Common gidA tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA FP0003 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 150026297 Common - hypothetical protein FP2266 16 None None None 150025332 Common - Glycosyl transferase, group 2 family protein FP1264 208 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150026323 Common - hypothetical protein FP2293 3 None None None 150025651 Common menE o-succinylbenzoate--CoA ligase FP1601 101 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150024198 Common yeeZ Putative enzyme of sugar metabolism YeeZ precursor FP0085 67 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150024147 Common ogt1 Methylated-DNA--[protein]-cysteineS-methyltransf erase FP0033 211 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 150024447 Common rpbA Putative RNA-binding protein RbpA FP0342 66 COG0724 COG0724, RNA-binding proteins (RRM domain) General function prediction only 150024153 Common - Probable ribosomal-protein-amino-adic N-acetyltransferase FP0039 21 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150025862 Common - hypothetical protein FP1817 3 None None None 150025791 Pathogen - hypothetical protein FP1743 1 None None None 150025048 Common - hypothetical protein FP0966 2 None None None 150025896 Common priA Primosomal protein N' FP1853 211 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 150024866 Common - Putative phage tail protein FP0776 49 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 150025056 Common efp Elongation factor P (EF-P) FP0975 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 150026270 Common - Putative lipoprotein FP2239 3 None None None 150024311 Common fabF 3-oxoacyl-(acyl-carrier-protein) synthase II FP0201 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150024305 Common - hypothetical protein FP0195 46 COG2954 COG2954, Uncharacterized protein conserved in bacteria Function unknown 150025024 Common acsA Acetate--CoA ligase FP0942 216 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 150025107 Common bfmBA 3-methyl-2-oxobutanoate dehydrogenase (2-methylpropanoyl-transferring) FP1028 218 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 150024593 Common - hypothetical protein FP0495 3 None None None 150025101 Common - hypothetical protein FP1022 18 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 150025478 Common - hypothetical protein FP1419 35 COG5495 COG5495, Uncharacterized conserved protein Function unknown 150024692 Common folE2 GTP cyclohydrolase I FP0597 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 150025120 Common pheT phenylalanyl-tRNA synthetase subunit beta FP1041 232 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 150024846 Common - hypothetical protein FP0753 47 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 150024507 Common kdtA 3-deoxy-D-manno-octulosonic-acid transferase FP0404 127 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 150024774 Common fahA Putative fumarylacetoacetase FP0680 47 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 150025746 Common valS valyl-tRNA synthetase FP1698 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150024428 Common fbaA fructose-bisphosphate aldolase FP0323 161 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 150025879 Common dapA Dihydrodipicolinate synthase FP1836 234 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 150025568 Common - hypothetical protein FP1512 48 COG4102 COG4102, Uncharacterized protein conserved in bacteria Function unknown 150026283 Common - Probable tRNA-dihydrouridine synthase FP2252 211 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 150024137 Common - hypothetical protein FP0023 58 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 150024566 Common - Carboxy-terminal processing protease precursor FP0463 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150025872 Common rprX Two-component system sensor histidine kinase RprX FP1827 219 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150025559 Pathogen - hypothetical protein FP1503 1 None None None 150025658 Common - Putative sugar-transporting permease FP1608 46 COG0738 FucP, Fucose permease Carbohydrate transport and metabolism 150024371 Common - hypothetical protein FP0263 1 None None None 150024505 Common - hypothetical protein FP0402 174 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 150026493 Common - hypothetical protein FP2465 2 None None None 150024856 Common - Probable transcriptional regulator, LysR family FP0763 128 COG0583 LysR, Transcriptional regulator Transcription 150026478 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase FP2450 180 COG0756 Dut, dUTPase Nucleotide transport and metabolism 150025355 Common - Putative sugar epimerase FP1287 1 None None None 150024796 Common - Probable transcriptional regulatory protein, Crp/Fnr family FP0703 135 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150024806 Common - hypothetical protein FP0713 39 COG4748 COG4748, Uncharacterized conserved protein Function unknown 150025492 Common rpmB 50S ribosomal protein L28 FP1433 153 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 150024762 Common natB Probable ABC-type Na(+)-transporting system, permease component FP0668 45 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 150024919 Common - hypothetical protein FP0829 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 150025545 Common fecA ABC-type iron(III) dicitrate-transport system component, TonB-dependent outer membrane receptor FecA precursor FP1489 74 COG4772 FecA, Outer membrane receptor for Fe3+-dicitrate Inorganic ion transport and metabolism 150025566 Common - Probable TonB-dependent outer membrane receptorprecursor FP1510 9 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150024839 Common rimK Ribosomal protein S6 modification protein RimK FP0746 122 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 150025094 Common - Probable two-component system response regulatory protein FP1015 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150024892 Common - hypothetical protein FP0802 16 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 150025140 Common - Probable methyltransferase FP1061 211 COG0313 COG0313, Predicted methyltransferases General function prediction only 150024949 Pathogen - hypothetical protein FP0859 1 None None None 150024361 Common gldA Gliding motility protein GldA FP0252 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150024433 Common dfrA Dihydrofolate reductase FP0328 148 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 150025666 Common gcp O-sialoglycoprotein endopeptidase FP1616 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 150025381 Common rpoA DNA-directed RNA polymerase subunit alpha FP1313 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 150024801 Common - Probable cysteine desulfurase FP0708 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 150026107 Common gldB Gliding motility protein GldB FP2069 6 None None None 150024421 Common - hypothetical protein FP0316 6 COG4319 COG4319, Ketosteroid isomerase homolog Function unknown 150025258 Common rpsU 30S ribosomal protein S21 FP1190 14 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 150025717 Common cafA Ribonuclease G FP1667 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 150026088 Common rpe Ribulose-phosphate 3-epimerase FP2049 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 150025061 Pathogen - hypothetical protein FP0980 2 None None None 150025444 Common - Probable ABC-type transport system, permease component FP1378 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 150025829 Common - hypothetical protein FP1783 2 None None None 150024389 Common - Probable M36 fungalysin family metalloprotease precursor FP0281 25 None None None 150024769 Common - Probable transcriptional regulator, PadR family FP0675 55 COG1695 COG1695, Predicted transcriptional regulators Transcription 150024992 Pathogen - hypothetical protein FP0907 1 None None None 150025998 Common - hypothetical protein FP1956 8 None None None 150024998 Common - hypothetical protein FP0913 23 COG3877 COG3877, Uncharacterized protein conserved in bacteria Function unknown 150024759 Common - hypothetical protein FP0665 1 None None None 150026353 Common - hypothetical protein FP2323 2 None None None 150025610 Common - hypothetical protein FP1559 11 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 150026198 Common - hypothetical protein FP2161 3 None None None 150024514 Common purT phosphoribosylglycinamide formyltransferase 2 FP0411 211 COG0027 PurT, Formate-dependent phosphoribosylglycinamide formyltransferase (GAR transformylase) Nucleotide transport and metabolism 150025210 Common - Phosphoglucomutase/phosphomannomutase family protein FP1138 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 150024463 Common phoP Two-component system response regulatory protein involved in phosphate regulation FP0358 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150025197 Common - hypothetical protein FP1125 23 None None None 150025329 Common - Glycosyl transferase, group 2 family protein FP1261 217 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150026467 Common - Acyl-CoA hydrolase family protein FP2439 131 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 150024430 Common - Probable tRNA/rRNA methyltransferase FP0325 189 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 150024697 Common - hypothetical protein FP0602 193 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 150026224 Pathogen - hypothetical protein FP2188 1 None None None 150025279 Common - hypothetical protein FP1211 8 None None None 150025467 Common - hypothetical protein FP1408 21 COG4365 COG4365, Uncharacterized protein conserved in bacteria Function unknown 150025925 Common dcp2 Peptidyl-dipeptidase Dcp2 FP1883 123 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 150024167 Common yqiW Protein of unknown function YqiW FP0053 11 None None None 150026458 Common glyS glycyl-tRNA synthetase FP2429 87 COG0423 GRS1, Glycyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 150025882 Common - Bifunctional protein CoaBC : Phosphopantothenoylcysteine decarboxylase and Phosphopantothenate--cysteine ligase FP1839 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 150026498 Common - hypothetical protein FP2470 12 None None None 150026454 Pathogen - Probable lipoprotein precursor FP2425 1 None None None 150025119 Common - hypothetical protein FP1040 1 None None None 150025750 Common - LemA family protein FP1702 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 150025388 Common rplO 50S ribosomal protein L15 FP1320 189 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 150026463 Common - pantothenate kinase FP2434 124 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 150025595 Common - Probable transcriptional regulator, AraC family FP1544 119 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150025322 Common - hypothetical protein FP1254 2 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 150024449 Common rpsP 30S ribosomal protein S16 FP0344 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 150025782 Common - Probable transcriptional regulator, AsnC family FP1734 143 COG1522 Lrp, Transcriptional regulators Transcription 150026164 Common - Probable amino acid-transporting permease FP2126 183 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150024969 Common - Protein of unknown function precursor FP0879 2 None None None 150024666 Common - hypothetical protein FP0571 2 None None None 150024745 Common - Probable aminopeptidase FP0650 48 COG2234 Iap, Predicted aminopeptidases General function prediction only 150024179 Common - hypothetical protein FP0065 13 None None None 150026279 Common - Probable 6-pyruvoyltetrahydrobiopterin synthase FP2248 90 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 150025030 Common ydzA Protein YdzA of unknown function FP0948 18 None None None 150026409 Common fabH3 3-oxoacyl-(acyl carrier protein) synthase III FP2379 230 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 150025764 Common - Putative M48 family metalloprotease FP1716 126 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 150025575 Common - Probable CRISPR-associated (Cas) protein. csn1 family, subtype Nmeni FP1524 20 COG3513 COG3513, Uncharacterized protein conserved in bacteria Function unknown 150025523 Common - hypothetical protein FP1467 4 None None None 150025108 Common - Probable oxidoreductase FP1029 55 COG3491 PcbC, Isopenicillin N synthase and related dioxygenases General function prediction only 150024690 Common - Protein of unknown function; putative adhesin FP0595 51 COG5492 COG5492, Bacterial surface proteins containing Ig-like domains Cell motility and secretion 150025788 Common - hypothetical protein FP1740 85 COG4121 COG4121, Uncharacterized conserved protein Function unknown 150024133 Common mltD Membrane-bound lytic murein transglycosylase D precursor FP0019 142 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 150024899 Pathogen - hypothetical protein FP0809 1 None None None 150024330 Common ygfA 5-formyltetrahydrofolate cyclo-ligase FP0220 87 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 150024830 Pathogen - hypothetical protein FP0737 1 None None None 150026191 Common - hypothetical protein FP2154 2 None None None 150026147 Common - hypothetical protein FP2109 2 None None None 150025038 Common hisH imidazole glycerol phosphate synthase subunit HisH FP0956 221 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 150025957 Common - Probable DNA polymerase III subunit FP1915 218 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 150025431 Common purE Phosphoribosylaminoimidazole carboxylase catalytic subunit FP1363 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 150024162 Common - Probable two-component system sensor histidine kinase FP0048 224 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 150025113 Common - hypothetical protein FP1034 3 None None None 150024582 Common - hypothetical protein FP0484 17 COG4226 HicB, Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters Function unknown 150026081 Common - Protein of unknown function related to deoxyribodipyrimidine photolyase FP2042 59 COG3046 COG3046, Uncharacterized protein related to deoxyribodipyrimidine photolyase General function prediction only 150025271 Pathogen - hypothetical protein FP1203 1 None None None 150025946 Common - Putative muramidase FP1904 11 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 150026234 Pathogen - hypothetical protein FP2203 1 None None None 150024827 Common - Probable RNA methyltransferase FP0734 189 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 150025190 Pathogen - hypothetical protein FP1118 1 None None None 150025228 Common ccoN/ccoO Cytochrome c oxidase, cbb3-type, subunit I and II FP1156 164 COG3278 CcoN, Cbb3-type cytochrome oxidase, subunit 1 Posttranslational modification, protein turnover, chaperones 150025762 Common lon S16 family, ATP-dependent endopeptidase La FP1714 211 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 150024358 Common - Putative phospho-2-dehydro-3-deoxyheptonate aldolase FP0249 137 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 150025625 Common - hypothetical protein FP1574 2 None None None 150024219 Common panD Aspartate 1-decarboxylase FP0107 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 150026131 Common ppnK inorganic polyphosphate/ATP-NAD kinase FP2093 240 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 150025426 Common - hypothetical protein FP1358 220 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 150024752 Common menF Isochorismate synthase FP0658 178 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 150026277 Common - Probable acyltransferase FP2246 113 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 150025416 Common - hypothetical protein FP1348 40 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 150024401 Common - Probable ABC-type transport system, membrane fusion efflux protein precursor component FP0295 120 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150026154 Common - Probable membrane fusion efflux protein FP2116 171 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150025313 Common - hypothetical protein FP1245 4 None None None 150024673 Common - hypothetical protein FP0578 3 None None None 150024720 Pathogen - hypothetical protein FP0625 1 None None None 150024254 Common - Probable alcohol dehydrogenase FP0142 165 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 150024659 Common - hypothetical protein FP0564 7 None None None 150026156 Common deoC Deoxyribose-phosphate aldolase FP2118 123 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 150025066 Common - hypothetical protein FP0985 4 None None None 150025975 Common - Protein of unknown function; putative anti ECF-type sigma factor FP1933 2 None None None 150025950 Common ppiC Probable peptidyl-prolyl cis-trans isomerase PpiC FP1908 206 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 150025350 Common - putative carbamoyl phosphate synthase large subunit FP1282 57 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 150026252 Common nuoK NADH dehydrogenase I, K subunit FP2221 159 COG0713 NuoK, NADH:ubiquinone oxidoreductase subunit 11 or 4L (chain K) Energy production and conversion 150025174 Common nth DNA-(apurinic or apyrimidinic site) lyase FP1101 237 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 150026125 Common - hypothetical protein FP2087 57 COG1950 COG1950, Predicted membrane protein Function unknown 150025814 Common - hypothetical protein FP1766 44 None None None 150025304 Common - hypothetical protein FP1236 64 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 150026524 Common - hypothetical protein FP2497 2 None None None 150024608 Common trpC Indole-3-glycerol phosphate synthase FP0510 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 150025142 Common tdk Thymidine kinase FP1063 47 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 150025913 Common - Probable aminotransferase involved in lipopolysaccharide biosynthesis FP1870 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 150025687 Common wbhW Protein of unknown function WbhW FP1637 6 None None None 150024939 Common uvrA2 Excinuclease ABC, A subunit UvrA2 FP0849 240 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 150024457 Common - Probable arsenate reductase (glutaredoxin) FP0352 11 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 150025805 Common - Probable transcriptional regulator, AraC family FP1757 76 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150024767 Common - hypothetical protein FP0673 6 None None None 150025743 Common - hypothetical protein FP1695 1 None None None 150026264 Common - Probable lipoprotein precursor FP2233 72 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 150025260 Common - hypothetical protein FP1192 7 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 150025092 Common - Probable short-chain type dehydrogenase FP1013 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150026109 Common - Probable two-component system response regulatory protein FP2071 167 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 150024639 Common - Putative biopolymer transporter FP0542 135 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 150025165 Common rhlE Putative ATP-dependent RNA helicase RhlE FP1092 232 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150024760 Common - ATP-dependent RNA helicase, DEAD box family FP0666 214 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150025088 Common - hypothetical protein FP1009 52 COG2102 COG2102, Predicted ATPases of PP-loop superfamily General function prediction only 150025724 Common menD Menaquinone biosynthesis protein MenD : 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase and 2-oxoglutarate decarboxylase FP1676 91 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 150024232 Common - hypothetical protein FP0120 2 None None None 150026424 Common sufA Scaffold protein for Fe-S assembly, SufA FP2394 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 150024493 Pathogen - hypothetical protein FP0388 1 None None None 150026201 Common - Putative two-component system response regulatory protein FP2165 1 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 150025868 Common - hypothetical protein FP1823 1 None None None 150026068 Common cynT Carbonic anhydrase FP2029 151 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 150025482 Common truA tRNA pseudouridine synthase A FP1423 233 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 150025186 Common - hypothetical protein FP1113 4 None None None 150026100 Common ftsI Peptidoglycan glycosyltransferase FtsI precursor FP2062 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 150025824 Common - hypothetical protein FP1778 26 COG4420 COG4420, Predicted membrane protein Function unknown 150024327 Common ileS isoleucyl-tRNA synthetase FP0217 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150025484 Common folP Dihydropteroate synthase FP1425 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 150026024 Common groES co-chaperonin GroES FP1984 215 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 150026292 Common - hypothetical protein FP2261 3 None None None 150025898 Common yfkH Protein of unknown function YfkH FP1855 82 COG1295 Rbn, Predicted membrane protein Function unknown 150025168 Common - hypothetical protein FP1095 4 None None None 150025870 Common ytxJ Protein of unknown function YtxJ FP1825 8 None None None 150026445 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase FP2416 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 150024757 Common pyrE Orotate phosphoribosyltransferase FP0663 106 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 150025861 Common - hypothetical protein FP1816 25 COG0730 COG0730, Predicted permeases General function prediction only 150024298 Common sfp Probable phosphopantetheinyl transferase FP0188 11 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 150026337 Common - hypothetical protein FP2307 2 None None None 150025077 Common - Probable myosin-crossreactive antigen FP0998 25 COG4716 COG4716, Myosin-crossreactive antigen Function unknown 150025456 Common murF UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase FP1390 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 150025699 Common - hypothetical protein FP1649 15 None None None 150024962 Common - Putative endonuclease FP0872 4 None None None 150025502 Common aroK Shikimate kinase FP1443 194 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 150025498 Common - hypothetical protein FP1439 31 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 150024301 Common ltd L-threonine 3-dehydrogenase FP0191 103 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150024641 Common - Membrane protein TerC family, possibly involvedin tellurium resistance FP0544 105 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 150024905 Pathogen - hypothetical protein FP0815 1 None None None 150024591 Pathogen - hypothetical protein FP0493 1 None None None 150026441 Common - hypothetical protein FP2412 5 None None None 150024170 Pathogen - hypothetical protein FP0056 1 None None None 150026513 Common - Putative RNA binding protein with S1 RNA-binding domain FP2485 201 COG2183 Tex, Transcriptional accessory protein Transcription 150026427 Common - Probable M1 family aminopeptidase FP2397 84 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 150024676 Common secA preprotein translocase subunit SecA FP0581 216 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 150024499 Common - hypothetical protein FP0396 8 None None None 150025858 Pathogen - hypothetical protein FP1813 1 None None None 150024411 Pathogen - hypothetical protein FP0306 2 None None None 150025265 Common - hypothetical protein FP1197 6 None None None 150025217 Common - hypothetical protein FP1145 5 None None None 150024293 Common - Enoyl-CoA hydratase/isomerase family protein FP0183 161 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 150024207 Common - hypothetical protein FP0094 32 None None None 150025406 Common rplD 50S ribosomal protein L4 FP1338 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 150024772 Common - hypothetical protein FP0678 4 None None None 150024559 Common rplM 50S ribosomal protein L13 FP0456 224 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 150024648 Common - Probable transcriptional regulator FP0551 16 COG2378 COG2378, Predicted transcriptional regulator Transcription 150024880 Pathogen - hypothetical protein FP0790 1 None None None 150024555 Common - Putative sensor (PAS) domain for methyl-accepting chemotaxis sensory transducer FP0452 84 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 150024351 Common - hypothetical protein FP0242 25 COG1694 MazG, Predicted pyrophosphatase General function prediction only 150024423 Pathogen - hypothetical protein FP0318 1 None None None 150024738 Common - hypothetical protein FP0643 4 None None None 150025554 Common argS arginyl-tRNA synthetase FP1498 248 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150026508 Common - hypothetical protein FP2480 4 None None None 150026376 Common - Glyoxalase family protein FP2346 2 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 150025369 Common - Sodium:solute symporter FP1301 71 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 150024605 Common trpA tryptophan synthase subunit alpha FP0507 219 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 150024264 Common - Probable hydrolase FP0154 191 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150025509 Common - hypothetical protein FP1453 4 None None None 150026009 Common - Glycine/D-amino acid oxidases (deaminating) family protein FP1969 30 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 150026363 Common - Probable S41A family C-terminal processing peptidase precursor FP2333 181 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150025398 Common rpsQ 30S ribosomal protein S17 FP1330 225 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 150026027 Common rpmH 50S ribosomal protein L34 FP1987 191 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 150024202 Common feoA Ferrous iron transport protein A FP0089 9 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 150024941 Common - Probable TonB-dependent outer membrane receptorprecursor FP0851 84 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150024706 Common - hypothetical protein FP0611 80 COG0795 COG0795, Predicted permeases General function prediction only 150025182 Common - Asparaginase 2 FP1109 84 COG1446 COG1446, Asparaginase Amino acid transport and metabolism 150026321 Common - hypothetical protein FP2290 17 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 150025851 Common npdA NAD-dependent deacetylase FP1806 150 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 150024313 Common - hypothetical protein FP0203 2 None None None 150025560 Common - Probable ABC-type transport system, ATPase component FP1504 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 150026228 Common - hypothetical protein FP2197 12 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 150026387 Common truB tRNA pseudouridine synthase B FP2357 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 150024951 Common - Putative lipid A biosynthesis acyltransferase FP0861 18 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 150025135 Common - hypothetical protein FP1056 1 None None None 150026073 Common - hypothetical protein FP2034 1 None None None 150026056 Common - Putative outer membrane protein FP2017 6 None None None 150025777 Common - Probable peroxiredoxin FP1729 205 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150026399 Common pepC Bleomycin hydrolase FP2369 14 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 150024987 Common - Peptidase, M48 family FP0902 19 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 150025986 Common - LemA family protein FP1944 131 COG1704 LemA, Uncharacterized conserved protein Function unknown 150024859 Common gltP Probable proton glutamate symport protein GltP FP0766 164 COG1301 GltP, Na+/H+-dicarboxylate symporters Energy production and conversion 150025541 Common - Thioredoxin family protein FP1485 3 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 150025374 Common - hypothetical protein FP1306 12 None None None 150024786 Common - hypothetical protein FP0692 2 None None None 150024922 Pathogen - hypothetical protein FP0832 1 None None None 150025711 Common - hypothetical protein FP1661 12 None None None 150024212 Common - Penicillin-binding protein FP0100 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 150026501 Common purD Phosphoribosylamine--glycine ligase FP2473 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 150025734 Common - hypothetical protein FP1686 55 COG1284 COG1284, Uncharacterized conserved protein Function unknown 150026392 Common - Probable membrane-associated phospholipid phosphatase FP2362 8 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 150024618 Common - TPR-domain containing protein FP0520 52 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 150025103 Common - Probable M43 cytophagalysin family metalloprotease precursor FP1024 11 COG3291 COG3291, FOG: PKD repeat General function prediction only 150026456 Common - Putative amidophosphoribosyltransferase FP2427 141 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 150025765 Common - hypothetical protein FP1717 35 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150025571 Pathogen - hypothetical protein FP1515 1 None None None 150025093 Common phrB1 Deoxyribodipyrimidine photolyase PhrB1 FP1014 132 COG0415 PhrB, Deoxyribodipyrimidine photolyase DNA replication, recombination, and repair 150026276 Common recA Recombinase A FP2245 222 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 150026397 Common - HIT family protein FP2367 188 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 150025385 Common rpmJ 50S ribosomal protein L36 FP1317 75 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 150024439 Common - hypothetical protein FP0334 77 COG1259 COG1259, Uncharacterized conserved protein Function unknown 150025888 Pathogen - hypothetical protein FP1845 1 None None None 150025807 Pathogen - hypothetical protein FP1759 1 None None None 150026452 Pathogen - hypothetical protein FP2423 1 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 150024743 Common - hypothetical protein FP0648 23 None None None 150025004 Common - Cytochrome c oxidase family protein FP0919 98 COG2993 CcoO, Cbb3-type cytochrome oxidase, cytochrome c subunit Energy production and conversion 150026083 Common - Probable nucleoside-diphosphate-sugar epimerase FP2044 69 COG0702 COG0702, Predicted nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150024328 Common dksA DnaK suppressor protein FP0218 28 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 150025837 Common idi Isopentenyl-diphosphate delta-isomerase FP1792 50 COG1443 Idi, Isopentenyldiphosphate isomerase Lipid metabolism 150025546 Common - Acyl-CoA hydrolase family protein FP1490 129 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 150025525 Common lipA lipoyl synthase FP1469 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 150026145 Common - Cytochrome c oxidase family protein FP2107 34 COG1845 CyoC, Heme/copper-type cytochrome/quinol oxidase, subunit 3 Energy production and conversion 150024966 Common recJ Single-stranded-DNA-specific exonuclease RecJ FP0876 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 150024595 Common - Probable ribosomal-protein-amino-adic N-acetyltransferase FP0497 125 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150025147 Common ald Alanine dehydrogenase FP1068 168 COG0686 Ald, Alanine dehydrogenase Amino acid transport and metabolism 150024776 Common tktN Transketolase, N-terminal subunit FP0682 222 COG3959 COG3959, Transketolase, N-terminal subunit Carbohydrate transport and metabolism 150026104 Common pcbD Probable 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoic acid hydrolase FP2066 162 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150024857 Common - ThiJ/PfpI family protein FP0764 105 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 150024525 Common - Probable ABC-type transport system, ATPase and permease components FP0422 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 150025358 Pathogen - hypothetical protein FP1290 1 None None None 150024785 Common - Probable lipoprotein precursor FP0691 3 None None None 150024231 Common - Putative 8-amino-7-oxononanoate synthase FP0119 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 150024360 Common pheA Prephenate dehydratase FP0251 212 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 150024798 Pathogen - hypothetical protein FP0705 1 None None None 150024956 Common - hypothetical protein FP0866 15 None None None 150024367 Common - hypothetical protein FP0259 74 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 150026185 Pathogen - hypothetical protein FP2148 1 None None None 150024545 Common - hypothetical protein FP0442 13 None None None 150025345 Common wbpM WbpM protein involved in UDP-D-Qui2NAc biosynthesis (a nucleotide sugar precursor for antigen-O biosynthesis) FP1277 199 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150025205 Common - hypothetical protein FP1133 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 150025823 Common trmU tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase FP1775 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 150025674 Common - hypothetical protein FP1624 11 None None None 150025564 Common - hypothetical protein FP1508 2 None None None 150024296 Common pnuC Nicotinamide mononucleotide transporter PnuC FP0186 56 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 150024189 Common - Probable lipoprotein precursor FP0075 49 COG3488 COG3488, Predicted thiol oxidoreductase Energy production and conversion 150025366 Common - Probable tyrosine-protein kinase involved in exopolysaccharide biosynthesis FP1298 129 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 150026045 Common - Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase family protein FP2006 186 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 150024995 Common - Probable M61 family peptidase FP0910 50 COG3975 COG3975, Predicted protease with the C-terminal PDZ domain General function prediction only 150025396 Common rplX 50S ribosomal protein L24 FP1328 215 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 150026325 Common - hypothetical protein FP2295 5 None None None 150025954 Common - hypothetical protein FP1912 45 COG4198 COG4198, Uncharacterized conserved protein Function unknown 150025927 Common - hypothetical protein FP1885 36 COG4628 COG4628, Uncharacterized conserved protein Function unknown 150024200 Common - Probable glycosyl hydrolase FP0087 36 None None None 150025216 Common - hypothetical protein FP1144 2 None None None 150025667 Common - hypothetical protein FP1617 201 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 150025578 Pathogen - hypothetical protein FP1527 1 None None None 150025404 Common rplB 50S ribosomal protein L2 FP1336 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 150025612 Common - hypothetical protein FP1561 123 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 150026116 Common - Polyprenyl synthetase FP2078 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 150026246 Common kynU Kynureninase FP2215 65 COG3844 COG3844, Kynureninase Amino acid transport and metabolism 150024634 Common yajC Preprotein translocase YajC subunit FP0536 124 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 150024442 Common pdhB Pyruvate dehydrogenase E1 component, beta subunit FP0337 218 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 150024655 Pathogen - hypothetical protein FP0560 1 None None None 150025152 Common purC phosphoribosylaminoimidazole-succinocarboxamide synthase FP1079 192 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 150026494 Common - hypothetical protein FP2466 54 COG1664 CcmA, Integral membrane protein CcmA involved in cell shape determination Cell envelope biogenesis, outer membrane 150025659 Common yojE Probable permease YojE FP1609 116 COG2962 RarD, Predicted permeases General function prediction only 150024879 Pathogen - hypothetical protein FP0789 1 None None None 150025052 Pathogen - hypothetical protein FP0971 1 None None None 150026291 Common - hypothetical protein FP2260 2 None None None 150024319 Common ruvC Holliday junction resolvase FP0209 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 150024688 Pathogen - hypothetical protein FP0593 1 None None None 150025157 Common - hypothetical protein FP1084 11 None None None 150025890 Common ligA DNA ligase (NAD+) FP1847 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 150024531 Common thiC thiamine biosynthesis protein ThiC FP0428 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism 150024864 Pathogen - hypothetical protein FP0774 1 None None None 150025902 Pathogen - hypothetical protein FP1859 1 None None None 150024758 Common - hypothetical protein FP0664 2 None None None 150025752 Common pdxH Pyridoxamine 5'-phosphate oxidase FP1704 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 150024549 Common ilvC Ketol-acid reductoisomerase FP0446 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 150025503 Common crtY Lycopene cyclase FP1447 15 None None None 150024474 Common - hypothetical protein FP0369 3 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 150025043 Common - hypothetical protein FP0961 2 COG4244 COG4244, Predicted membrane protein Function unknown 150025900 Common hmp Nitric oxide dioxygenase FP1857 144 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 150024512 Common - hypothetical protein FP0409 1 None None None 150024981 Common - Peptidase, M16 family FP0891 167 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 150025790 Common - hypothetical protein FP1742 11 COG4696 COG4696, Uncharacterized protein conserved in bacteria Function unknown 150024913 Pathogen - hypothetical protein FP0823 1 None None None 150026476 Pathogen - hypothetical protein FP2448 1 None None None 150024307 Common - Carbohydrate kinase, PfkB family FP0197 31 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 150025472 Common - Probable sugar O-acetyltransferase precursor FP1413 86 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 150026058 Common fspA Flavobacterial-specific protein antigen FspA precursor FP2019 2 None None None 150024172 Common - Putative carboxypeptidase FP0058 86 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 150024695 Common lgt Prolipoprotein diacylglyceryl transferase FP0600 166 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 150026046 Common - Putative transcriptional regulator FP2007 128 COG1678 COG1678, Putative transcriptional regulator Transcription 150025640 Common - hypothetical protein FP1590 15 COG0795 COG0795, Predicted permeases General function prediction only 150025843 Common crcB Protein of unknown function CrcB FP1798 187 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 150024129 Common sprD Putative cell surface protein precursor SprD FP0015 1 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 150025542 Common - hypothetical protein FP1486 4 None None None 150025129 Pathogen - hypothetical protein FP1050 1 None None None 150025532 Common ffh Signal recognition particle protein FP1476 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 150025731 Common - hypothetical protein FP1683 18 COG2391 COG2391, Predicted transporter component General function prediction only 150026384 Common tag DNA-3-methyladenine glycosylase I FP2354 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 150024551 Common ilvB Acetolactate synthase, large subunit FP0448 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 150024872 Pathogen - hypothetical protein FP0782 1 None None None 150024635 Common pyrF Orotidine-5'-phosphate decarboxylase FP0537 73 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 150025514 Common gpmA Phosphoglycerate mutase FP1458 103 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 150024339 Common - Probable M23/M37 family peptidase FP0229 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 150024815 Common - Membrane protein, TerC family FP0722 95 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 150025920 Pathogen - hypothetical protein FP1878 1 None None None 150025270 Common lysS lysyl-tRNA synthetase FP1202 243 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 150024249 Common - hypothetical protein FP0137 3 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 150026036 Common murB UDP-N-acetylmuramate dehydrogenase FP1996 189 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 150024221 Common - hypothetical protein FP0109 84 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 150025698 Common - hypothetical protein FP1648 10 None None None 150024376 Common metK S-adenosylmethionine synthetase FP0268 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 150025000 Common - hypothetical protein FP0915 3 None None None 150025634 Common - Putative acetyltransferase FP1583 9 COG0456 RimI, Acetyltransferases General function prediction only 150024810 Common rho transcription termination factor Rho FP0717 208 COG1158 Rho, Transcription termination factor Transcription 150026099 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase FP2061 211 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 150026166 Common - hypothetical protein FP2128 2 None None None 150025122 Common - hypothetical protein FP1043 10 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 150026090 Common - hypothetical protein FP2052 149 COG1610 COG1610, Uncharacterized conserved protein Function unknown 150025780 Common - Probable amino acid-transporting permease FP1732 159 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 150025137 Common - hypothetical protein FP1058 1 None None None 150024261 Common - Probable phospholipid N-methyltransferase FP0151 36 COG3963 COG3963, Phospholipid N-methyltransferase Lipid metabolism 150025149 Pathogen - hypothetical protein FP1071 2 COG3188 FimD, P pilus assembly protein, porin PapC Cell motility and secretion / Intracellular trafficking and secretion 150024968 Common - hypothetical protein FP0878 6 None None None 150026215 Pathogen - hypothetical protein FP2179 1 None None None 150024732 Common - hypothetical protein FP0637 2 None None None 150026003 Common engA GTP-binding protein EngA FP1961 232 COG1160 COG1160, Predicted GTPases General function prediction only 150025584 Common - hypothetical protein FP1533 5 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150024268 Common - hypothetical protein FP0158 76 COG1479 COG1479, Uncharacterized conserved protein Function unknown 150025741 Common - hypothetical protein FP1693 1 None None None 150026389 Common - hypothetical protein FP2359 4 None None None 150024807 Pathogen - hypothetical protein FP0714 1 None None None 150024709 Common dnaB Replicative DNA helicase FP0614 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 150024567 Common - dCMP deaminase FP0464 101 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 150025243 Common - Protein of unknown function; putative adhesin FP1171 114 None None None 150026114 Common - Protein of unknown function; putative anti ECF-type sigma factor FP2076 2 None None None 150024915 Pathogen - hypothetical protein FP0825 1 None None None 150025057 Common lpxA UDP-N-acetylglucosamine acyltransferase FP0976 193 COG1043 LpxA, Acyl- acyl carrier protein 150025984 Common - Probable secreted M23/M37 family peptidase FP1942 192 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 150024927 Common - hypothetical protein FP0837 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 150026050 Common - hypothetical protein FP2011 32 COG3911 COG3911, Predicted ATPase General function prediction only 150025572 Common - Two-component system sensor histidine kinase FP1516 108 COG3275 LytS, Putative regulator of cell autolysis Signal transduction mechanisms 150025819 Common argD Acetylornithine/ succinyldiaminopimelatetransamin ase FP1771 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 150024900 Pathogen - N-acetylmuramoyl-L-alanine amidase FP0810 4 None None None 150024837 Common - Probable metalloprotease FP0744 87 COG2321 COG2321, Predicted metalloprotease General function prediction only 150026505 Common - Probable nucleoside-diphosphate-sugar epimerase FP2477 234 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 150025372 Common - hypothetical protein FP1304 15 COG4874 COG4874, Uncharacterized protein conserved in bacteria containing a pentein-type domain Function unknown 150026015 Common topA DNA topoisomerase I FP1975 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 150026065 Common - Probable hydrolase (HAD superfamily) FP2026 42 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 150024708 Common accA Acetyl-coenzyme A carboxylase carboxyl transferase alpha subunit FP0613 186 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 150025991 Common - hypothetical protein FP1949 12 COG5293 COG5293, Uncharacterized protein conserved in bacteria Function unknown 150024472 Common - hypothetical protein FP0367 74 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 150025233 Common - hypothetical protein FP1161 61 COG2836 COG2836, Uncharacterized conserved protein Function unknown 150026126 Common - Probable hydrolase FP2088 152 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150025776 Common - Thioredoxin family protein FP1728 89 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 150025090 Common - hypothetical protein FP1011 7 None None None 150024824 Pathogen - hypothetical protein FP0731 1 None None None 150026196 Common - hypothetical protein FP2159 102 COG3177 COG3177, Uncharacterized conserved protein Function unknown 150025504 Common - Probable transcriptional regulator, MerR family FP1448 35 COG0789 SoxR, Predicted transcriptional regulators Transcription 150024784 Common - Probable outer membrane protein precursor FP0690 18 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150026248 Common rplU 50S ribosomal protein L21 FP2217 210 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 150025496 Common - Fumarylacetoacetate hydrolase family protein FP1437 179 COG0179 MhpD, 2-keto-4-pentenoate hydratase/2-oxohepta-3-ene-1,7-dioic acid hydratase (catechol pathway) Secondary metabolites biosynthesis, transport, and catabolism 150024735 Common serC phosphoserine aminotransferase FP0640 98 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 150024353 Pathogen - hypothetical protein FP0244 1 None None None 150025907 Common - Glycosyl transferase, group 1 family protein FP1864 104 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150024271 Common tyrS Tyrosine--tRNA ligase FP0161 217 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150024930 Common - Probable acyltransferase FP0840 50 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 150026138 Common - Carbonic anhydrase/acetyltransferase family protein FP2100 203 COG0663 PaaY, Carbonic anhydrases/acetyltransferases, isoleucine patch superfamily General function prediction only 150025026 Common - hypothetical protein FP0944 86 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 150024877 Pathogen - hypothetical protein FP0787 2 None None None 150026492 Common - hypothetical protein FP2464 1 None None None 150025956 Common - hypothetical protein FP1914 1 None None None 150024632 Common nusB N utilization substance protein B homolog (NusBprotein) FP0534 92 COG0781 NusB, Transcription termination factor Transcription 150025286 Common - hypothetical protein FP1218 122 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 150025857 Common - Thioredoxin family protein FP1812 234 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 150026364 Common - hypothetical protein FP2334 134 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 150025189 Pathogen - hypothetical protein FP1117 1 None None None 150025627 Pathogen - hypothetical protein FP1576 1 None None None 150026370 Pathogen - hypothetical protein FP2340 1 None None None 150026288 Common - Glycosyl transferase, group 2 family protein FP2257 179 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150026311 Common darA Dialkylrecorsinol condensing enzyme DarA FP2280 7 None None None 150024643 Common - Probable outer membrane protein, OmpA family FP0546 10 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 150026200 Pathogen - hypothetical protein FP2163 2 None None None 150025863 Common - Probable ATP-dependent RNA helicase, DEAD/DEAH box family FP1818 235 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 150026074 Common - hypothetical protein FP2035 2 None None None 150024557 Common rpsB 30S ribosomal protein S2 FP0454 223 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 150025292 Common - hypothetical protein FP1224 3 None None None 150025792 Common - hypothetical protein FP1744 2 None None None 150025360 Common - hypothetical protein FP1292 2 None None None 150025380 Common rplQ 50S ribosomal protein L17 FP1312 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 150026426 Common - Probable S8 subtilisin family serine endopeptidase precursor FP2396 131 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 150025977 Common - Probable pyrophosphohydrolase FP1935 128 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 150025816 Common - putative SAM-dependent methyltransferase FP1768 28 COG3129 COG3129, Predicted SAM-dependent methyltransferase General function prediction only 150024628 Common csaA Protein secretion chaperone CsaA FP0530 81 COG0073 ARC1, EMAP domain General function prediction only 150024886 Pathogen - hypothetical protein FP0796 1 None None None 150025219 Common mutL DNA mismatch repair protein MutL FP1147 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 150024205 Common sdhC Succinate dehydrogenase, cytochrome b subunit FP0092 33 None None None 150024882 Pathogen - hypothetical protein FP0792 1 None None None 150024657 Common - hypothetical protein FP0562 62 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 150024625 Common gyrB DNA gyrase B subunit FP0527 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 150025293 Pathogen - hypothetical protein FP1225 1 None None None 150024502 Common sppA Protease IV (signal peptide peptidase) FP0399 190 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 150024303 Common - Protein of unknown function precursor FP0193 5 None None None 150026106 Common gldC Gliding motility protein GldC FP2068 3 None None None 150024721 Pathogen - hypothetical protein FP0626 1 None None None 150025367 Common - Probable polysaccharide exporter FP1299 33 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 150025031 Common mscS2 Probable small-conductance mechanosensitive ionchannel MscS2 FP0949 96 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 150025010 Common - Probable transcriptional regulatory protein, Crp/Fnr family FP0925 72 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150025130 Common - Putative glutamine cyclotransferase FP1051 22 COG3823 COG3823, Glutamine cyclotransferase Posttranslational modification, protein turnover, chaperones 150026343 Common - hypothetical protein FP2313 2 None None None 150024667 Common argK Periplasmic transport binding protein kinase ArgK FP0572 99 COG1703 ArgK, Putative periplasmic protein kinase ArgK and related GTPases of G3E family Amino acid transport and metabolism 150026418 Common - hypothetical protein FP2388 2 None None None 150025202 Common parB Chromosome partitioning protein ParB FP1130 186 COG1475 Spo0J, Predicted transcriptional regulators Transcription 150024725 Common trmE tRNA modification GTPase TrmE FP0630 227 COG0486 ThdF, Predicted GTPase General function prediction only 150025315 Common - Glycosyl transferase, group 1 family protein FP1247 46 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150025194 Pathogen - hypothetical protein FP1122 1 None None None 150024761 Common - Probable sigma-54 dependent two-component system response regulatory protein FP0667 225 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150025172 Common - hypothetical protein FP1099 10 None None None 150026294 Common - Probable polysaccharide deacetylase FP2263 120 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150025832 Common - hypothetical protein FP1786 2 None None None 150024953 Common - hypothetical protein FP0863 80 COG2968 COG2968, Uncharacterized conserved protein Function unknown 150025468 Common ndk Nucleoside-diphosphate kinase FP1409 229 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 150024210 Common fmo Flavomodulin FP0097 7 None None None 150025700 Common - hypothetical protein FP1650 2 None None None 150026207 Common - hypothetical protein FP2171 36 COG1479 COG1479, Uncharacterized conserved protein Function unknown 150026261 Common nuoC NADH dehydrogenase I, C subunit FP2230 172 COG0852 NuoC, NADH:ubiquinone oxidoreductase 27 kD subunit Energy production and conversion 150025436 Pathogen - hypothetical protein FP1368 1 None None None 150025308 Common - hypothetical protein FP1240 3 None None None 150025017 Common - Probable two-component system response regulatory protein-glycosyl transferase, group 2 family protein FP0935 229 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 150025166 Common - hypothetical protein FP1093 4 None None None 150026309 Common darC1 Probable acyl carrier protein involved in flexirubin-type pigment biosynthesis DarC1 FP2278 6 None None None 150026000 Common - hypothetical protein FP1958 4 None None None 150025083 Common - Probable metalloprotease FP1004 98 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 150025479 Common kdsC 3-deoxy-manno-octulosonate-8-phosphatase FP1420 103 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 150025826 Common hutI Imidazolonepropionase FP1780 116 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 150026266 Common haaO 3-hydroxyanthranilate 3,4-dioxygenase FP2235 16 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 150026169 Common yitI Acetyltransferase, GNAT family, YitI FP2132 16 COG0456 RimI, Acetyltransferases General function prediction only 150025075 Common - Probable transcriptional regulator, AraC family FP0994 37 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 150026097 Common murD UDP-N-acetylmuramoylalanine--D-glutamateligase FP2059 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 150024485 Common - hypothetical protein FP0380 2 None None None 150025703 Common - Probable outer membrane protein FP1653 10 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 150024460 Common - hypothetical protein FP0355 5 COG2849 COG2849, Uncharacterized protein conserved in bacteria Function unknown 150025111 Common udp Uridine phosphorylase FP1032 59 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 150025339 Pathogen - hypothetical protein FP1271 1 None None None 150024718 Common - RNA polymerase ECF-type sigma factor FP0623 160 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150024971 Common - Probable membrane fusion efflux protein precursor FP0881 149 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150026472 Pathogen - hypothetical protein FP2444 1 None None None 150024346 Common - Probable lyase FP0237 93 COG3185 COG3185, 4-hydroxyphenylpyruvate dioxygenase and related hemolysins Amino acid transport and metabolism / General function prediction only 150025424 Common - Protein of unknown function containing LysM domain FP1356 50 COG1652 XkdP, Uncharacterized protein containing LysM domain Function unknown 150025800 Common mqo malate:quinone oxidoreductase FP1752 57 COG0579 COG0579, Predicted dehydrogenase General function prediction only 150026526 Common gltX glutamyl-tRNA synthetase FP2499 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 150024217 Common - hypothetical protein FP0105 12 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 150024378 Common - hypothetical protein FP0270 9 COG3292 COG3292, Predicted periplasmic ligand-binding sensor domain Signal transduction mechanisms 150024947 Common - Putative DNA binding protein FP0857 2 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 150024195 Common - Probable M1 family metalloprotease precursor FP0082 154 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 150026223 Pathogen - hypothetical protein FP2187 1 None None None 150024180 Common proC Pyrroline-5-carboxylate reductase FP0066 208 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 150025970 Common - Acyl-CoA dehydrogenase family protein FP1928 167 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 150024671 Pathogen - hypothetical protein FP0576 1 None None None 150025263 Common dnaQ Probable DNA polymerase III, epsilon subunit FP1195 71 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 150025681 Common - Putative mannosyltransferase FP1631 196 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150026318 Common hutH2 Histidine ammonia-lyase FP2287 110 COG2986 HutH, Histidine ammonia-lyase Amino acid transport and metabolism 150024495 Common umuD SOS mutagenesis; error-prone repair; processed to UmuD'; forms complex with UmuC FP0390 63 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 150025255 Common tuf elongation factor Tu FP1184 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 150026414 Common - hypothetical protein FP2384 7 None None None 150025963 Common prfA Peptide chain release factor 1 (RF-1) FP1921 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 150024284 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0174 18 None None None 150025064 Common - Probable TonB-dependent outer membrane receptorprecursor FP0983 11 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150026274 Common - hypothetical protein FP2243 16 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 150024580 Common - Probable penicillin-binding protein FP0482 113 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 150025722 Common - hypothetical protein FP1672 172 COG2962 RarD, Predicted permeases General function prediction only 150026210 Common - hypothetical protein FP2174 4 None None None 150025099 Pathogen - Probable two-component system histidine-containing phosphotransfer protein (HPt) FP1020 1 COG2198 ArcB, FOG: HPt domain Signal transduction mechanisms 150025170 Common - hypothetical protein FP1097 2 None None None 150026255 Common nuoH NADH dehydrogenase I, H subunit FP2224 191 COG1005 NuoH, NADH:ubiquinone oxidoreductase subunit 1 (chain H) Energy production and conversion 150025222 Common - hypothetical protein FP1150 9 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 150024402 Common - Probable outer membrane efflux protein precursor FP0296 4 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150025324 Common neuB Sialic acid synthase (N-acetylneuraminic acid synthetase) FP1256 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 150024976 Common - hypothetical protein FP0886 50 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 150024418 Common - Probable mevalonate kinase FP0313 9 COG1577 ERG12, Mevalonate kinase Lipid metabolism 150024125 Common holB Probable DNA polymerase III, delta prime subunit FP0011 113 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 150024560 Common nrdA Ribonucleoside-diphosphate reductase, alpha subunit FP0457 221 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 150024543 Common - Putative outer membrane protein FP0440 6 None None None 150024647 Common yfbK Probable outer membrane protein precursor YfbK FP0550 56 COG2304 COG2304, Uncharacterized protein containing a von Willebrand factor type A (vWA) domain General function prediction only 150025364 Common wbpO UDP-N-acetyl-D-galactosamine dehydrogenase FP1296 206 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 150024958 Common uvrD ATP-dependent DNA helicase UvrD FP0868 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 150026430 Common - Probable multidrug resistance protein precursor. AcrB/AcrD/AcrF family protein FP2401 176 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 150025905 Common - Glycosyl transferase, group 2 family protein FP1862 212 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150024896 Pathogen - hypothetical protein FP0806 2 None None None 150025326 Common - Glycosyl transferase, group 2 family protein FP1258 19 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 150024257 Common pgi Glucose-6-phosphate isomerase FP0145 198 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 150025394 Common rpsN 30S ribosomal protein S14 FP1326 212 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 150024663 Common - Probable cytochrome c peroxidase FP0568 94 COG1858 MauG, Cytochrome c peroxidase Inorganic ion transport and metabolism 150025413 Common - Probable outer membrane protein, Omp121 family FP1345 62 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 150025596 Pathogen - hypothetical protein FP1545 1 None None None 150025441 Common - hypothetical protein FP1375 11 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 150026043 Common ribH Riboflavin synthase, beta subunit FP2003 222 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 150025448 Common - hypothetical protein FP1382 3 None None None 150024348 Common - Probable ABC-type transport system, permease component FP0239 114 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 150025549 Common - hypothetical protein FP1493 3 None None None 150024251 Common - hypothetical protein FP0139 1 None None None 150025261 Common - hypothetical protein FP1193 3 None None None 150024716 Common - hypothetical protein FP0621 2 None None None 150025669 Common - Probable M43 cytophagalysin family metalloprotease precursor FP1619 10 None None None 150024383 Common aspS aspartyl-tRNA synthetase FP0275 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150025787 Common - hypothetical protein FP1739 2 None None None 150024437 Pathogen - hypothetical protein FP0332 1 None None None 150025020 Common - Probable glycosyl hydrolase FP0938 11 COG3934 COG3934, Endo-beta-mannanase Carbohydrate transport and metabolism 150025840 Common pyrB Aspartate carbamoyltransferase FP1795 239 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 150025660 Common - hypothetical protein FP1610 204 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 150026481 Common - Major facilitator superfamily (MFS) permease FP2453 33 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150024365 Common metX Homoserine O-acetyltransferase FP0256 128 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 150026168 Common pepE peptidase E FP2130 28 COG3340 PepE, Peptidase E Amino acid transport and metabolism 150024404 Common fbp fructose-1,6-bisphosphatase FP0299 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 150025274 Common acdS 1-aminocyclopropane-1-carboxylate deaminase FP1206 70 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 150024321 Common - Glycosyl transferase, group 2 family protein FP0211 50 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150025379 Common carA carbamoyl phosphate synthase small subunit FP1311 237 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 150024341 Common fpp1 Psychrophilic metalloprotease Fpp1 precursor FP0231 28 COG4935 COG4935, Regulatory P domain of the subtilisin-like proprotein convertases and other proteases Posttranslational modification, protein turnover, chaperones 150024416 Pathogen - hypothetical protein FP0311 1 None None None 150024741 Common parE DNA topoisomerase IV subunit B FP0646 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 150026085 Common pnp polynucleotide phosphorylase/polyadenylase FP2046 235 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 150024434 Common - hypothetical protein FP0329 4 None None None 150026390 Common ftsX Cell division protein FtsX FP2360 69 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 150025810 Common - Probable dioxygenase FP1762 146 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 150025835 Common - Probable peroxiredoxin FP1790 220 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 150025886 Pathogen - hypothetical protein FP1843 1 None None None 150024756 Common - Protein of unknown function, Nudix family FP0662 4 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 150025581 Common - hypothetical protein FP1530 6 None None None 150025944 Common purA adenylosuccinate synthetase FP1902 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 150025145 Common - Probable two-component system response regulatory protein FP1066 222 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150025754 Common - Putative antibiotic resistance protein FP1706 79 COG0506 PutA, Proline dehydrogenase Amino acid transport and metabolism 150025527 Common - Probable two-component system sensor histidine kinase FP1471 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 150024193 Common - hypothetical protein FP0079 30 COG3751 EGL-9, Predicted proline hydroxylase Posttranslational modification, protein turnover, chaperones 150024224 Common - Probable TonB-dependent outer membrane receptorprecursor FP0112 42 COG4206 BtuB, Outer membrane cobalamin receptor protein Coenzyme metabolism 150025301 Common recQ1 ATP-dependent DNA helicase RecQ1 FP1233 237 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 150024369 Common - hypothetical protein FP0261 1 None None None 150025629 Common - hypothetical protein FP1578 22 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 150024187 Common - Protein of unknown function precursor FP0073 16 None None None 150026102 Common mraW S-adenosyl-methyltransferase MraW FP2064 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 150024964 Common ltaE Threonine aldolase FP0874 116 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 150025760 Common cmk Cytidylate kinase FP1712 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 150025649 Common - Probable arsenate reductase (glutaredoxin) FP1599 123 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 150024535 Common thiG Thiazole biosynthesis protein ThiG FP0432 167 COG2022 ThiG, Uncharacterized enzyme of thiazole biosynthesis Nucleotide transport and metabolism 150024415 Common mvaD Diphosphomevalonate decarboxylase FP0310 28 COG3407 MVD1, Mevalonate pyrophosphate decarboxylase Lipid metabolism 150024523 Common - Probable outer membrane efflux protein precursor FP0420 11 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 150026143 Common - hypothetical protein FP2105 195 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 150025639 Common ribBA Bifunctional enzyme : 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II FP1589 232 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 150024233 Common - Putative outer membrane protein precursor FP0121 6 None None None 150024521 Common - Probable methyltransferase FP0418 44 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 150025214 Common - Probable outer membrane protein FP1142 13 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150025531 Common folD Bifunctional protein FolD : methylenetetrahydrofolate dehydrogenase and methenyltetrahydrofolate cyclohydrolase FP1475 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 150025642 Common ftsK DNA translocase FtsK FP1592 198 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 150024528 Pathogen - hypothetical protein FP0425 1 None None None 150024337 Common - hypothetical protein FP0227 14 None None None 150024813 Common - hypothetical protein FP0720 7 None None None 150025336 Common - hypothetical protein FP1268 37 None None None 150024604 Common - Probable metalloprotease FP0506 2 COG2321 COG2321, Predicted metalloprotease General function prediction only 150025028 Common - Putative DNA or RNA helicase FP0946 121 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 150025080 Common - hypothetical protein FP1001 68 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 150024778 Common - Probable outer membrane protein, OmpA family FP0684 46 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 150025730 Common - hypothetical protein FP1682 28 COG3714 COG3714, Predicted membrane protein Function unknown 150025678 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase FP1628 146 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 150024166 Common plsC 1-acylglycerol-3-phosphate O-acyltransferase FP0052 103 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 150026134 Common - Probable outer membrane protein precursor FP2096 152 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 150025351 Common wcgN Putative undecaprenyl-phosphate glycosyl-1-phosphate transferase FP1283 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 150025737 Common - hypothetical protein FP1689 7 None None None 150024275 Common - Glycosyl transferase, group 2 family protein FP0165 126 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150024870 Common - hypothetical protein FP0780 2 None None None 150024820 Common - hypothetical protein FP0727 4 None None None 150025241 Common - Probable outer membrane protein, OmpA family FP1169 126 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 150025690 Common gmd GDP-mannose 4,6-dehydratase FP1640 226 COG1089 Gmd, GDP-D-mannose dehydratase Cell envelope biogenesis, outer membrane 150026382 Common aat leucyl/phenylalanyl-tRNA--protein transferase FP2352 134 COG2360 Aat, Leu/Phe-tRNA-protein transferase Posttranslational modification, protein turnover, chaperones 150024936 Common - hypothetical protein FP0846 1 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 150024250 Common pphA Phosphoprotein phosphatase FP0138 70 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 150024849 Common - Probable Fe-S oxidoreductase C-terminal region FP0756 117 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 150025282 Common - Probable ribosomal-protein-amino-adic N-acetyltransferase FP1214 73 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 150024829 Common - Probable modification methyltransferase Sau3AI FP0736 89 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 150025636 Common - hypothetical protein FP1585 8 None None None 150025534 Common - Probable lipoprotein precursor FP1478 34 COG3487 IrpA, Uncharacterized iron-regulated protein Inorganic ion transport and metabolism 150024247 Common - hypothetical protein FP0135 114 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 150025125 Pathogen - hypothetical protein FP1046 1 None None None 150024974 Common sdaA L-serine ammonia-lyase FP0884 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 150025230 Common ccoP Cytochrome c oxidase, cbb3-type, subunit III FP1158 73 COG2010 CccA, Cytochrome c, mono- and diheme variants Energy production and conversion 150024127 Common - hypothetical protein FP0013 25 None None None 150024988 Common uvrB excinuclease ABC subunit B FP0903 229 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 150026516 Common rpiB Ribose 5-phosphate isomerase FP2488 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 150024909 Pathogen - hypothetical protein FP0819 1 None None None 150025318 Common - Glycosyl transferase, group 2 family protein FP1250 25 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 150024451 Common yfiC Protein of unknown function YfiC FP0346 100 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 150025620 Pathogen - hypothetical protein FP1569 1 None None None 150024287 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0177 22 None None None 150026066 Common - hypothetical protein FP2027 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 150025965 Common - hypothetical protein FP1923 3 COG3295 COG3295, Uncharacterized protein conserved in bacteria Function unknown 150026438 Common sucB Dihydrolipoyllysine-residue succinyltransferasecomponent of 2-oxoglutarate dehydrogenase complex FP2409 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 150025892 Common rplI 50S ribosomal protein L9 FP1849 213 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 150024444 Common ppa Inorganic diphosphatase FP0339 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 150025767 Common mrsB2 protein-methionine-S-oxide reductase MrsB2 FP1719 194 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 150025875 Common - Protein of unknown function, putative adhesine FP1830 11 None None None 150025036 Common hisF Imidazole glycerol phosphate synthase subunit HisF FP0954 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 150024653 Common - Probably involved in regulation of translation initiation FP0558 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 150026244 Common pac Penicillin G acylase precursor FP2213 77 COG2366 COG2366, Protein related to penicillin acylase General function prediction only 150024510 Pathogen - hypothetical protein FP0407 1 None None None 150026327 Pathogen - Putative bacterial general secretion pathway protein FP2297 1 None None None 150024686 Common - hypothetical protein FP0591 4 None None None 150025457 Pathogen - hypothetical protein FP1391 2 None None None 150026304 Common hpaIIR Type II restriction endonuclease HpaII FP2273 4 None None None 150025159 Pathogen - hypothetical protein FP1086 1 None None None 150024157 Common hemC Hydroxymethylbilane synthase FP0043 222 COG0181 HemC, Porphobilinogen deaminase Coenzyme metabolism 150024637 Common - Hydrolase, alpha/beta fold family FP0539 160 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 150026496 Common paaE Probable phenylacetic acid degradation NADH oxidoreductase PaaE FP2468 153 COG1018 Hmp, Flavodoxin reductases (ferredoxin-NADPH reductases) family 1 Energy production and conversion 150025918 Pathogen - hypothetical protein FP1876 1 None None None 150025237 Common yueD Benzil reductase YueD FP1165 208 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150024388 Common - Probable M36 fungalysin family metalloprotease precursor FP0280 20 None None None 150024143 Pathogen - hypothetical protein FP0029 1 None None None 150024476 Common - hypothetical protein FP0371 2 None None None 150024575 Common - hypothetical protein FP0477 44 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 150024852 Common - hypothetical protein FP0759 53 COG1814 COG1814, Uncharacterized membrane protein Function unknown 150024140 Common atoD 3-oxoacid CoA-transferase subunit A family protein AtoD FP0026 103 COG1788 AtoD, Acyl CoA:acetate/3-ketoacid CoA transferase, alpha subunit Lipid metabolism 150026281 Common asnC asparaginyl-tRNA synthetase FP2250 219 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 150024563 Common - MarC family integral membrane protein precursor FP0460 152 COG2095 MarC, Multiple antibiotic transporter Intracellular trafficking and secretion 150024613 Common - Nitroreductase FP0515 78 COG0778 NfnB, Nitroreductase Energy production and conversion 150024792 Common - hypothetical protein FP0699 8 None None None 150024236 Common pheS phenylalanyl-tRNA synthetase subunit alpha FP0124 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 150025938 Common - hypothetical protein FP1896 43 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 150025604 Common - hypothetical protein FP1553 76 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 150026474 Common yoeB Toxin YoeB FP2446 52 COG4115 COG4115, Uncharacterized protein conserved in bacteria Function unknown 150024533 Common thiD Phosphomethylpyrimidine kinase FP0430 219 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 150024842 Common - hypothetical protein FP0749 12 COG5010 TadD, Flp pilus assembly protein TadD, contains TPR repeats Intracellular trafficking and secretion 150024119 Common - Probable outer membrane protein, OmpH family FP0005 4 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 150025474 Common - hypothetical protein FP1415 2 None None None 150025045 Common - hypothetical protein FP0963 6 None None None 150024547 Common - Major facilitator superfamily (MFS) protein FP0444 25 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150025550 Pathogen - hypothetical protein FP1494 1 None None None 150024597 Common - hypothetical protein FP0499 3 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 150025657 Common - hypothetical protein FP1607 1 None None None 150024203 Common feoB Ferrous iron transport protein B FP0090 163 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 150026405 Common pckA phosphoenolpyruvate carboxykinase FP2375 97 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 150026313 Common - Probable acyltransferase FP2282 41 COG4261 COG4261, Predicted acyltransferase General function prediction only 150026369 Common pepX1 Xaa-Pro dipeptidyl-peptidase FP2339 104 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 150025740 Common kdpA potassium-transporting ATPase subunit A FP1692 96 COG2060 KdpA, K+-transporting ATPase, A chain Inorganic ion transport and metabolism 150025855 Common - Probable membrane fusion efflux protein precursor FP1810 175 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 150024916 Pathogen - hypothetical protein FP0826 1 None None None 150025284 Common degQ Protease DegQ precursor FP1216 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 150026470 Common - hypothetical protein FP2442 31 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 150025755 Common aroB 3-dehydroquinate synthase FP1707 207 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 150025235 Common hemN coproporphyrinogen III oxidase FP1163 202 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 150024174 Common tas Oxidoreductase Tas, aldo/keto reductase family FP0060 201 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 150025459 Common proS prolyl-tRNA synthetase FP1400 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 150024983 Common rpmI 50S ribosomal protein L35 FP0893 186 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 150026372 Common - hypothetical protein FP2342 2 COG1577 ERG12, Mevalonate kinase Lipid metabolism 150024355 Common - Probable type II endonuclease-methyltransferasefusion protein FP0246 107 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 150025438 Common gcvP glycine dehydrogenase FP1372 172 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 150024398 Common - Thioredoxin family protein FP0292 111 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 150024955 Common - Probable aminotransferase FP0865 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 150025493 Common cinA CinA-like protein FP1434 212 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 150026032 Common rmuC DNA recombination protein RmuC FP1992 143 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 150025618 Common - Probable endonuclease-methyltransferase fusion protein FP1567 54 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 150024577 Common menA 1,4-dihydroxy-2-naphthoateoctaprenyltransferase FP0479 66 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 150024645 Common - RNA polymerase ECF-type sigma factor FP0548 36 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 150024277 Common - Probable cell surface protein (Leucine-rich repeat protein) FP0167 24 None None None 150025204 Common ykuF Hypothetical oxidoreductase YkuF FP1132 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 150024727 Common - Probable ABC-type transport system, ATPase component FP0632 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 150024701 Common psd phosphatidylserine decarboxylase FP0606 93 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 150025297 Common - Probable FAD-dependent dehydrogenase FP1229 83 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 150024888 Pathogen - hypothetical protein FP0798 1 None None None 150024754 Common - hypothetical protein FP0660 4 None None None 150025586 Common - hypothetical protein FP1535 11 COG5340 COG5340, Predicted transcriptional regulator Transcription 150026362 Common surE stationary phase survival protein SurE FP2332 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 150024862 Common - Probable cell wall-associated hydrolase FP0769 147 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 150025288 Common - hypothetical protein FP1220 49 COG1579 COG1579, Zn-ribbon protein, possibly nucleic acid-binding General function prediction only 150025446 Common - hypothetical protein FP1380 7 None None None 150024713 Common - hypothetical protein FP0618 54 COG3781 COG3781, Predicted membrane protein Function unknown 150024884 Pathogen - hypothetical protein FP0794 2 None None None 150026367 Common - Probable proton-dependent di-tripeptide transporter FP2337 80 COG3104 PTR2, Dipeptide/tripeptide permease Amino acid transport and metabolism 150024844 Common - hypothetical protein FP0751 17 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 150026341 Pathogen - hypothetical protein FP2311 1 None None None 150025942 Common oxaA putative inner membrane protein translocase component YidC FP1900 208 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 150024623 Common - hypothetical protein FP0525 3 None None None 150025735 Common - Probable two-component system sensor histidine kinase FP1687 223 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 150026178 Common - Major facilitator superfamily (MFS) permease FP2141 179 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 150025154 Common phoH Phosphate starvation-inducible protein PhoH FP1081 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 150025747 Common - hypothetical protein FP1699 6 None None None 150025631 Common panB2 3-methyl-2-oxobutanoate hydroxymethyltransferase panB2 FP1580 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 150026195 Pathogen - hypothetical protein FP2158 1 None None None 150024565 Common - Putative pyridine nucleotide-disulphide oxidoreductase, class-II family protein FP0462 5 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 150024466 Common pstS ABC-type phosphate-transport system, binding protein precursor component PstS FP0361 169 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 150025982 Common - Methylmalonyl-CoA mutase FP1940 110 COG1884 Sbm, Methylmalonyl-CoA mutase, N-terminal domain/subunit Lipid metabolism 150024407 Common lysC Aspartate kinase FP0302 234 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 150025139 Common - hypothetical protein FP1060 15 None None None 150024317 Common - Probable arylformamidase FP0207 2 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 150026360 Common lpxB Lipid-A-disaccharide synthase FP2330 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 150026076 Common - hypothetical protein FP2037 84 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 150024799 Common lpdA2 Dihydrolipoyl dehydrogenase FP0706 245 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 150026052 Common - hypothetical protein FP2013 6 None None None 150026518 Common - hypothetical protein FP2490 1 None None None 150024155 Common hemE Uroporphyrinogen decarboxylase FP0041 181 COG0407 HemE, Uroporphyrinogen-III decarboxylase Coenzyme metabolism 150024446 Common dnaE/dnaQ Probable DNA polymerase III, alpha and epsilon subunits FP0341 218 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 150026268 Common - hypothetical protein FP2237 16 None None None 150026450 Common rodA Rod shape-determining protein RodA FP2421 206 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 150026128 Common - Putative ABC-type transport system, ATPase component FP2090 232 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 150025972 Common - hypothetical protein FP1930 7 None None None 150024902 Pathogen - hypothetical protein FP0812 1 None None None 150025104 Common - Putative ferredoxin-dependent glutamate synthase FP1025 202 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 150026017 Common - hypothetical protein FP1977 11 None None None 150025774 Common - Acyl-CoA dehydrogenase family protein FP1726 164 COG1960 CaiA, Acyl-CoA dehydrogenases Lipid metabolism 150024573 Common infB translation initiation factor IF-2 FP0470 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 150025706 Common - hypothetical protein FP1656 5 None None None 150025993 Common - hypothetical protein FP1951 1 None None None 150025224 Common - Probable transcriptional regulatory protein, Crp/Fnr family FP1152 170 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150026095 Common murG N-acetylglucosaminyl transferase FP2057 211 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 150026520 Common folB Dihydroneopterin aldolase FP2493 59 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 150024123 Common - Probable cAMP-binding protein FP0009 25 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 150025922 Pathogen - hypothetical protein FP1880 1 None None None 150024294 Common - Probable protein chain release factor FP0184 102 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 150026484 Common - Probable TonB-dependent outer membrane ferrichrome-iron receptor precursor FP2456 98 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 150026023 Common secG Preprotein translocase SecG subunit FP1983 2 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 150026307 Common - hypothetical protein FP2276 6 None None None 150025207 Common rpmE2 50S ribosomal protein L31 type B FP1135 132 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 150026183 Pathogen - hypothetical protein FP2146 1 None None None 150025211 Common msbA Probable lipid A transport system, ATPase and permease components FP1139 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 150025809 Common pafA Alkaline phosphatase FP1761 19 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 150025865 Common guaB IMP dehydrogenase FP1820 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 150025591 Common - hypothetical protein FP1540 3 None None None 150026238 Common tonB Protein TonB FP2207 5 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 150024945 Pathogen - Putative two-component system response regulatory protein FP0855 2 COG0784 CheY, FOG: CheY-like receiver Signal transduction mechanisms 150024894 Pathogen - hypothetical protein FP0804 1 None None None 150026377 Common mtgA Monofunctional biosynthetic peptidoglycan transglycosylase FP2347 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 150025353 Common fnlC FnlC protein involved in UDP-L-FucpNAc biosynthesis (a nucleotide sugar precursor for antigen-O bisynthesis). Probable UDP-2-acetamino-2,6-dideoxy-L-talose 2-epimerase FP1285 157 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 150025929 Common - hypothetical protein FP1887 2 None None None 150025348 Common - hypothetical protein FP1280 31 COG0622 COG0622, Predicted phosphoesterase General function prediction only 150024589 Common - hypothetical protein FP0491 29 COG5545 COG5545, Predicted P-loop ATPase and inactivated derivatives General function prediction only 150026005 Common - Probable DnaJ-class molecular chaperone FP1965 3 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 150026257 Pathogen - hypothetical protein FP2226 1 None None None 150026421 Common sufD Fe-S assembly protein, SufD FP2391 172 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 150025002 Common - Cytochrome c family protein FP0917 3 None None None 150025248 Common rpoB DNA-directed RNA polymerase subunit beta FP1176 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 150024854 Common - Probable acyltransferase FP0761 109 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 150026231 Common ygcF Protein of unknown function YgcF FP2200 159 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 150026412 Common pdxA 4-hydroxythreonine-4-phosphate dehydrogenase FP2382 159 COG1995 PdxA, Pyridoxal phosphate biosynthesis protein Coenzyme metabolism 150025454 Common - Protein of unknown function, putative sulfolipid biosynthesis protein FP1388 8 None None None 150025337 Common - Probable ABC-type polysaccharide/polyol phosphate transport system, ATPase component FP1269 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 150025253 Common nusG Transcription antitermination protein NusG FP1181 215 COG0250 NusG, Transcription antiterminator Transcription 150024616 Common - Probable monooxygenase FP0518 33 COG0654 UbiH, 2-polyprenyl-6-methoxyphenol hydroxylase and related FAD-dependent oxidoreductases Coenzyme metabolism / Energy production and conversion 150025062 Common kdsB 3-deoxy-manno-octulosonate cytidylyltransferase FP0981 141 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 150025694 Common cca tRNA nucleotidyltransferase FP1644 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 150025377 Common eno Phosphopyruvate hydratase FP1309 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 150024723 Common - hypothetical protein FP0628 2 None None None 150025795 Common - hypothetical protein FP1747 18 COG3358 COG3358, Uncharacterized conserved protein Function unknown 150025116 Common - hypothetical protein FP1037 3 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 150026217 Pathogen - hypothetical protein FP2181 1 None None None 150026241 Common exbB Biopolymer transport ExbB protein FP2210 14 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 150026351 Common - hypothetical protein FP2321 2 None None None 150025488 Common tpiA Triose-phosphate isomerase FP1429 224 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 150024935 Common - hypothetical protein FP0845 104 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 150024601 Common - Probable membrane fusion efflux protein FP0503 169 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 150025295 Common - Probable transcriptional regulator, XRE family FP1227 36 COG5499 COG5499, Predicted transcription regulator containing HTH domain Transcription 150025019 Common - hypothetical protein FP0937 2 None None None 150024835 Common miaE tRNA-(MS[2]IO[6]A)-hydroxylase FP0742 40 COG4445 MiaE, Hydroxylase for synthesis of 2-methylthio-cis-ribozeatin in tRNA Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 150025949 Common - hypothetical protein FP1907 11 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 150025688 Common - Glycosyl transferase, group 2 family protein FP1638 138 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150025097 Common - hypothetical protein FP1018 36 COG3287 COG3287, Uncharacterized conserved protein Function unknown 150026416 Common - hypothetical protein FP2386 145 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 150024665 Common - hypothetical protein FP0570 52 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 150025192 Common - hypothetical protein FP1120 4 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 150025683 Common - Probable polysaccharide deacetylase FP1633 69 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 150025161 Common - Probable methyltransferase FP1088 11 None None None 150025849 Common - Putative 8-amino-7-oxononanoate synthase FP1804 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 150026402 Common asnC Regulatory protein AsnC FP2372 159 COG1522 Lrp, Transcriptional regulators Transcription 150024309 Common purN Phosphoribosylglycinamide formyltransferase FP0199 224 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 150026448 Common - hypothetical protein FP2419 6 None None None 150024323 Common - hypothetical protein FP0213 8 COG2839 COG2839, Uncharacterized protein conserved in bacteria Function unknown 150026333 Common - Probable outer membrane protein, OmpH family FP2303 5 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 150026503 Common - Glycosyl transferase, group 2 family protein FP2475 217 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 150025177 Common - Putative sensor (PAS) domain for methyl-accepting chemotaxis sensory transducer FP1104 80 COG2202 AtoS, FOG: PAS/PAC domain Signal transduction mechanisms 150026209 Common - hypothetical protein FP2173 32 COG5545 COG5545, Predicted P-loop ATPase and inactivated derivatives General function prediction only 150024487 Common - Protein of unknown function ; putative S46 family serine protease FP0382 21 None None None 150026112 Common - hypothetical protein FP2074 25 None None None 150026020 Common - Probable sigma-54-dependent transcriptional regulator FP1980 167 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 150025073 Common - Probable transcriptional regulator, TetR family FP0992 37 COG1309 AcrR, Transcriptional regulator Transcription 150025330 Common - Glycosyl transferase, group 1 family protein FP1262 225 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 150026263 Common nuoA NADH dehydrogenase I, A subunit FP2232 162 COG0838 NuoA, NADH:ubiquinone oxidoreductase subunit 3 (chain A) Energy production and conversion 150026136 Common - Outer membrane protein OmpH family P18 FP2098 13 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 150025033 Common - MutT/nudix family protein FP0951 147 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 150025047 Common - Probable DNA polymerase III subunit FP0965 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 150024822 Common - Probable modification methyltransferase FP0729 132 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 150026205 Common - Probable type III modification methyltransferase FP2169 95 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 150025085 Common ybcL Probable phospholipid-binding protein precursorYbcL FP1006 129 COG1881 COG1881, Phospholipid-binding protein General function prediction only 150024763 Common natA Probable ABC-type Na(+)-transporting system, ATPase component FP0669 249 COG4152 COG4152, ABC-type uncharacterized transport system, ATPase component General function prediction only 150025050 Common ppx Exopolyphosphatase FP0968 151 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism