Haemophilus influenzae PittEE, complete genome NC_009566 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 148826487 Common - hypothetical protein CGSHiEE_07690 10 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 148825498 Common - HemY CGSHiEE_01985 37 COG3071 HemY, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 148825294 Common pssA phosphatidylserine synthase CGSHiEE_00870 31 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 148825343 Common - hypothetical protein CGSHiEE_01135 8 None None None 148826710 Common - hypothetical protein CGSHiEE_08925 8 None None None 148825927 Common trpD anthranilate phosphoribosyltransferase CGSHiEE_04510 219 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 148825319 Common - DNA mismatch repair protein CGSHiEE_00995 16 COG3691 COG3691, Uncharacterized protein conserved in bacteria Function unknown 148826296 Common - heme exporter protein B CGSHiEE_06615 82 COG2386 CcmB, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 148826719 Pathogen - hypothetical protein CGSHiEE_08970 1 None None None 148825485 Common secF preprotein translocase subunit SecF CGSHiEE_01920 234 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 148826258 Common - hypothetical protein CGSHiEE_06405 143 COG2001 COG2001, Uncharacterized protein conserved in bacteria Function unknown 148826448 Common - hypothetical protein CGSHiEE_07475 4 None None None 148825616 Common - putative Mg2+ and Co2+ transporter CGSHiEE_02740 218 COG4536 CorB, Putative Mg2+ and Co2+ transporter CorB Inorganic ion transport and metabolism 148826271 Common rfaD ADP-L-glycero-D-mannoheptose-6-epimerase CGSHiEE_06480 198 COG0451 WcaG, Nucleoside-diphosphate-sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148826489 Common - lipopolysaccharide biosynthesis protein CGSHiEE_07700 30 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 148825870 Common - type I restriction/modification specificity protein CGSHiEE_04175 68 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 148825400 Pathogen - hypothetical protein CGSHiEE_01450 1 None None None 148825906 Common - threonyl-tRNA synthetase CGSHiEE_04375 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148825965 Common - fumarate/nitrate reduction transcriptional regulator CGSHiEE_04700 146 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 148826666 Pathogen - hypothetical protein CGSHiEE_08685 1 None None None 148826198 Common - branched-chain amino acid aminotransferase CGSHiEE_06075 188 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 148825911 Common - condesin subunit F CGSHiEE_04410 20 COG3006 MukF, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 148826753 Common recX recombination regulator RecX CGSHiEE_09160 82 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 148825651 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase CGSHiEE_02955 213 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 148825784 Common - cell morphogenesis/cell wall metabolism regulator CGSHiEE_03675 45 COG2846 COG2846, Regulator of cell morphogenesis and NO signaling Cell division and chromosome partitioning 148825185 Common ureA urease subunit gamma CGSHiEE_00285 96 COG0831 UreA, Urea amidohydrolase (urease) gamma subunit Amino acid transport and metabolism 148825137 Common cpdB bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein CGSHiEE_00045 6 COG3510 CmcI, Cephalosporin hydroxylase Defense mechanisms 148826610 Common - anaerobic C4-dicarboxylate transporter CGSHiEE_08375 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 148826329 Common - transcriptional regulator AraC family protein CGSHiEE_06810 142 COG4977 COG4977, Transcriptional regulator containing an amidase domain and an AraC-type DNA-binding HTH domain Transcription 148826191 Common cysB transcriptional regulator CysB CGSHiEE_06040 191 COG0583 LysR, Transcriptional regulator Transcription 148825454 Common - nitrate/nitrite sensor protein NarQ CGSHiEE_01720 129 COG3850 NarQ, Signal transduction histidine kinase, nitrate/nitrite-specific Signal transduction mechanisms 148825882 Common - deoxyguanosinetriphosphate triphosphohydrolase-like protein CGSHiEE_04235 159 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 148825638 Common - thioredoxin CGSHiEE_02870 232 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 148826579 Common - autoinducer-2 (AI-2) kinase CGSHiEE_08190 177 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148826066 Common - putative NAD(P)H oxidoreductase CGSHiEE_05300 89 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 148825304 Common - hydroxyethylthiazole kinase CGSHiEE_00920 78 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 148825506 Common - L-fuculose phosphate aldolase CGSHiEE_02035 156 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 148826707 Common - hypothetical protein CGSHiEE_08910 125 COG0551 TopA, Zn-finger domain associated with topoisomerase type I DNA replication, recombination, and repair 148826370 Common - 6-phosphofructokinase CGSHiEE_07055 160 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 148825792 Common - carboxy-terminal protease CGSHiEE_03715 182 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 148826698 Common - probable ABC transporter, ATP-binding protein CGSHiEE_08865 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148826251 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase CGSHiEE_06370 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 148826074 Common bioD dithiobiotin synthetase CGSHiEE_05340 14 COG2830 COG2830, Uncharacterized protein conserved in bacteria Function unknown 148826033 Common - hypothetical protein CGSHiEE_05080 4 None None None 148825935 Pathogen - hypothetical protein CGSHiEE_04550 2 None None None 148826096 Common alr alanine racemase CGSHiEE_05465 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 148825358 Common - iron (chelated) ABC transporter permease protein CGSHiEE_01210 186 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 148825201 Common pgk phosphoglycerate kinase CGSHiEE_00365 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 148825862 Common - acylneuraminate cytidylyltransferase CGSHiEE_04135 65 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 148825275 Common secG preprotein translocase subunit SecG CGSHiEE_00765 23 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 148825286 Common recR recombination protein RecR CGSHiEE_00820 168 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 148826473 Common - hypothetical protein CGSHiEE_07620 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 148825466 Common - dihydrodipicolinate synthase CGSHiEE_01790 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 148825159 Common - ribulose-phosphate 3-epimerase CGSHiEE_00155 94 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 148826505 Common - predicted positive regulator of sigma E CGSHiEE_07800 20 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 148826375 Common - cell filamentation protein CGSHiEE_07080 32 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 148826015 Common - 30S ribosomal protein S15 CGSHiEE_04970 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 148826520 Common - fumarate reductase flavoprotein subunit CGSHiEE_07885 226 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 148825197 Common - thymidine kinase CGSHiEE_00345 96 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 148825224 Common - probable oxidoreductase OrdL CGSHiEE_00500 19 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 148825313 Common - acetyl-CoA carboxylase carboxyltransferase subunit alpha CGSHiEE_00965 208 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 148825979 Common - thiamine biosynthesis protein ThiI CGSHiEE_04780 95 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 148825849 Common - transcription-repair coupling factor CGSHiEE_04040 228 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 148826482 Common - dTDP-glucose 46-dehydratase CGSHiEE_07665 232 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 148825510 Common fucI L-fucose isomerase CGSHiEE_02055 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 148825831 Pathogen - hypothetical protein CGSHiEE_03920 1 None None None 148826025 Common - translation initiation factor IF-3 CGSHiEE_05020 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 148825770 Common rnfD electron transport complex protein RnfD CGSHiEE_03605 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 148825440 Common - acyl-CoA thioester hydrolase YfbB CGSHiEE_01650 131 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148826432 Pathogen - hypothetical protein CGSHiEE_07395 1 None None None 148826608 Common - glycerol-3-phosphate acyltransferase CGSHiEE_08365 48 COG2937 PlsB, Glycerol-3-phosphate O-acyltransferase Lipid metabolism 148825517 Common metN DL-methionine transporter ATP-binding subunit CGSHiEE_02090 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 148825537 Common - hypothetical protein CGSHiEE_02260 176 COG0730 COG0730, Predicted permeases General function prediction only 148825245 Pathogen - hypothetical protein CGSHiEE_00605 1 None None None 148825474 Common tgt queuine tRNA-ribosyltransferase CGSHiEE_01855 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 148825247 Common - 1-(5-phosphoribosyl)-5-[(5-phosphoribosylamino)methylideneamino] imidazole-4-carboxamide isomerase CGSHiEE_00625 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 148826735 Common - elongation factor Tu CGSHiEE_09060 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 148825723 Common - glutamate racemase CGSHiEE_03340 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 148825809 Common - transposase CGSHiEE_03800 57 None None None 148825332 Common - predicted thioesterase CGSHiEE_01070 121 COG0824 FcbC, Predicted thioesterase General function prediction only 148825526 Common ribA GTP cyclohydrolase II CGSHiEE_02170 184 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 148826571 Common rplP 50S ribosomal protein L16 CGSHiEE_08140 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 148825879 Common queF 7-cyano-7-deazaguanine reductase CGSHiEE_04220 76 COG1525 COG1525, Micrococcal nuclease (thermonuclease) homologs DNA replication, recombination, and repair 148826456 Common - dihydrofolate reductase CGSHiEE_07515 149 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 148825398 Common aspS aspartyl-tRNA synthetase CGSHiEE_01440 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148825566 Pathogen - hypothetical protein CGSHiEE_02455 1 None None None 148825650 Common - DNA repair protein CGSHiEE_02940 209 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 148826365 Common - 3-isopropylmalate dehydrogenase CGSHiEE_07030 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 148825240 Common - F0F1 ATP synthase subunit alpha CGSHiEE_00580 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 148825392 Common - ribonuclease T CGSHiEE_01410 47 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 148825419 Common lnt apolipoprotein N-acyltransferase CGSHiEE_01545 219 COG4535 CorC, Putative Mg2+ and Co2+ transporter CorC Inorganic ion transport and metabolism 148826269 Common - deoxyribose-phosphate aldolase CGSHiEE_06470 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 148826480 Common - aminopeptidase B CGSHiEE_07655 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 148825741 Common glnD PII uridylyl-transferase CGSHiEE_03450 150 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 148826113 Common lolA outer-membrane lipoprotein carrier protein precursor CGSHiEE_05580 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 148825554 Common - Na(+)-translocating NADH-quinone reductase subunit C CGSHiEE_02365 48 COG2869 NqrC, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrC Energy production and conversion 148825637 Common - cystathionine gamma-synthase CGSHiEE_02855 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 148826262 Common - transaldolase B CGSHiEE_06425 196 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 148826006 Common - hypothetical protein CGSHiEE_04915 45 COG2062 SixA, Phosphohistidine phosphatase SixA Signal transduction mechanisms 148825838 Common - 16S pseudouridylate 516 synthase CGSHiEE_03965 197 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 148826121 Pathogen - hypothetical protein CGSHiEE_05620 1 None None None 148826237 Common - hypothetical protein CGSHiEE_06290 62 COG3028 COG3028, Uncharacterized protein conserved in bacteria Function unknown 148825997 Common - hypothetical protein CGSHiEE_04870 96 COG2510 COG2510, Predicted membrane protein Function unknown 148825254 Common - hypothetical protein CGSHiEE_00660 103 COG0354 COG0354, Predicted aminomethyltransferase related to GcvT General function prediction only 148825437 Common - alanine aminotransferase CGSHiEE_01635 221 COG1169 MenF, Isochorismate synthase Coenzyme metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148826228 Common - thioredoxin domain-containing protein CGSHiEE_06245 143 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 148826260 Common - hypothetical protein CGSHiEE_06415 4 None None None 148826755 Common - carbamate kinase CGSHiEE_09190 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 148826149 Common - HTH-type transcriptional regulator CGSHiEE_05780 143 COG0789 SoxR, Predicted transcriptional regulators Transcription 148826083 Common prfA peptide chain release factor 1 CGSHiEE_05385 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 148825706 Common rsmC 16S ribosomal RNA m2G1207 methyltransferase CGSHiEE_03255 152 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 148826133 Common - 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase CGSHiEE_05690 192 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 148825548 Common - Sec-independent protein translocase protein TatA/E CGSHiEE_02325 46 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 148826521 Common - fumarate reductase iron-sulfur subunit CGSHiEE_07890 208 COG0479 FrdB, Succinate dehydrogenase/fumarate reductase, Fe-S protein subunit Energy production and conversion 148826546 Common - phosphoenolpyruvate carboxykinase CGSHiEE_08015 98 COG1866 PckA, Phosphoenolpyruvate carboxykinase (ATP) Energy production and conversion 148825597 Common dcd deoxycytidine triphosphate deaminase CGSHiEE_02630 157 COG0717 Dcd, Deoxycytidine deaminase Nucleotide transport and metabolism 148826108 Common purU formyltetrahydrofolate deformylase CGSHiEE_05545 220 COG0788 PurU, Formyltetrahydrofolate hydrolase Nucleotide transport and metabolism 148825154 Common gyrB DNA gyrase subunit B CGSHiEE_00130 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 148826534 Common - fused methyl-galactoside transporter subunits of ABC superfamily: ATP-binding components CGSHiEE_07955 126 COG1609 PurR, Transcriptional regulators Transcription 148825361 Common - thiamine biosynthesis protein CGSHiEE_01225 87 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 148826097 Common pgi glucose-6-phosphate isomerase CGSHiEE_05470 197 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 148825214 Common - ribonuclease activity regulator protein RraA CGSHiEE_00450 80 COG0684 MenG, Demethylmenaquinone methyltransferase Coenzyme metabolism 148825970 Common - phosphoribosylaminoimidazole synthetase CGSHiEE_04725 232 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 148826289 Common - TPR-repeat-containing protein CGSHiEE_06580 39 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 148826748 Pathogen - hypothetical protein CGSHiEE_09135 1 None None None 148826161 Common - phosphoenolpyruvate carboxylase CGSHiEE_05850 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 148825425 Common - N-acetyl-anhydromuranmyl-L-alanine amidase CGSHiEE_01575 36 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148826217 Common - S-adenosylmethionine synthetase CGSHiEE_06180 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 148826468 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase CGSHiEE_07595 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 148825270 Common - virulence-associated protein D CGSHiEE_00740 3 COG3309 VapD, Uncharacterized virulence-associated protein D Function unknown 148825187 Common ureC urease subunit alpha CGSHiEE_00295 96 COG0804 UreC, Urea amidohydrolase (urease) alpha subunit Amino acid transport and metabolism 148826168 Common - peptide ABC transporter permease protein CGSHiEE_05885 207 COG4168 SapB, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 148826184 Common - arginine repressor CGSHiEE_05995 106 COG1090 COG1090, Predicted nucleoside-diphosphate sugar epimerase General function prediction only 148826401 Common - hypothetical protein CGSHiEE_07220 22 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 148825921 Common - phosphate-binding periplasmic protein precursor PstS CGSHiEE_04470 99 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 148826556 Common rpsM 30S ribosomal protein S13 CGSHiEE_08065 244 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 148825589 Common - N-acetylmannosamine kinase CGSHiEE_02570 96 COG1737 RpiR, Transcriptional regulators Transcription 148826253 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase CGSHiEE_06380 209 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 148825579 Common - anaerobic C4-dicarboxylate transporter CGSHiEE_02520 36 COG2704 DcuB, Anaerobic C4-dicarboxylate transporter General function prediction only 148826230 Common - cysteine/glutathione ABC transporter membrane/ATP-binding component CGSHiEE_06255 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 148825893 Common - ribonuclease G CGSHiEE_04290 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 148825751 Common - glucose-specific PTS system enzyme IIA component CGSHiEE_03500 96 COG1292 BetT, Choline-glycine betaine transporter Cell envelope biogenesis, outer membrane 148825236 Common - F0F1 ATP synthase subunit A CGSHiEE_00560 206 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 148825665 Common uvrC excinuclease ABC subunit C CGSHiEE_03025 117 COG0861 TerC, Membrane protein TerC, possibly involved in tellurium resistance Inorganic ion transport and metabolism 148826136 Common - multidrug efflux protein CGSHiEE_05715 157 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 148826208 Common - DNA ligase CGSHiEE_06135 29 COG1793 CDC9, ATP-dependent DNA ligase DNA replication, recombination, and repair 148825277 Common recR recombination protein RecR CGSHiEE_00775 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 148825969 Common purN phosphoribosylglycinamide formyltransferase CGSHiEE_04720 222 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 148826346 Common - Biotin synthase CGSHiEE_06905 175 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 148825690 Common - hypothetical protein CGSHiEE_03165 154 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 148825903 Common - DNA topoisomerase I CGSHiEE_04360 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 148825503 Common - shikimate 5-dehydrogenase CGSHiEE_02010 215 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 148825840 Common - malic enzyme CGSHiEE_03975 217 COG0281 SfcA, Malic enzyme Energy production and conversion 148826582 Common - hypothetical protein CGSHiEE_08215 102 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148825394 Common - predicted nucleic acid-binding protein, contains PIN domain CGSHiEE_01420 55 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 148826507 Common - tRNA (uracil-5-)-methyltransferase CGSHiEE_07810 161 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 148825713 Common - formate dehydrogenase accessory protein FdhE CGSHiEE_03290 132 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 148825424 Common - putative type IV pilin secretion protein CGSHiEE_01570 143 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 148825953 Pathogen - hypothetical protein CGSHiEE_04640 1 None None None 148826239 Common - hypothetical protein CGSHiEE_06300 64 COG1934 COG1934, Uncharacterized protein conserved in bacteria Function unknown 148825914 Common mukB cell division protein MukB CGSHiEE_04435 14 None None None 148825289 Common - hypothetical protein CGSHiEE_00835 26 COG3068 COG3068, Uncharacterized protein conserved in bacteria Function unknown 148826654 Common - DNA mismatch repair protein CGSHiEE_08625 50 COG1238 COG1238, Predicted membrane protein Function unknown 148826306 Common - probable amino-acid ABC transporter binding protein CGSHiEE_06665 179 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 148826142 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit CGSHiEE_05745 191 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 148826726 Common rplL 50S ribosomal protein L7/L12 CGSHiEE_09015 214 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 148826621 Pathogen - hypothetical protein CGSHiEE_08440 1 None None None 148826669 Common - DNA-binding transcriptional regulator IlvY CGSHiEE_08700 79 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 148826684 Common - iron-hydroxamate transporter permease subunit CGSHiEE_08785 188 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 148825800 Pathogen - hypothetical protein CGSHiEE_03755 1 None None None 148825135 Common - peptidase E CGSHiEE_00035 173 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 148826646 Common - hypothetical protein CGSHiEE_08585 7 COG3077 RelB, DNA-damage-inducible protein J DNA replication, recombination, and repair 148826442 Common tsf elongation factor Ts CGSHiEE_07445 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 148826284 Common - cell division protein ZipA CGSHiEE_06555 41 COG3115 ZipA, Cell division protein Cell division and chromosome partitioning 148826086 Common - hypothetical protein CGSHiEE_05400 4 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 148825766 Common - predicted Na+-dependent transporters of the SNF family protein CGSHiEE_03585 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 148825362 Common - putative ABC-type nitrate/sulfonate/bicarbonate transport system, permease component CGSHiEE_01230 190 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 148825938 Common - aspartate-semialdehyde dehydrogenase CGSHiEE_04565 34 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 148826427 Pathogen - hypothetical protein CGSHiEE_07370 1 None None None 148825469 Common - biopolymer transport protein CGSHiEE_01805 55 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 148826413 Common - extragenic suppressor CGSHiEE_07280 212 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 148826243 Common - chorismate mutase/prephenate dehydratase CGSHiEE_06320 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 148825604 Common - UDP-N-acetylmuramoylalanine-D-glutamate ligase-like protein CGSHiEE_02670 208 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 148825852 Common - SanA CGSHiEE_04065 39 COG2949 SanA, Uncharacterized membrane protein Function unknown 148825179 Common rpsF 30S ribosomal protein S6 CGSHiEE_00255 193 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 148826420 Common eno phosphopyruvate hydratase CGSHiEE_07335 126 COG0753 KatE, Catalase Inorganic ion transport and metabolism 148825571 Common - phosphatidylserine decarboxylase CGSHiEE_02480 95 COG0688 Psd, Phosphatidylserine decarboxylase Lipid metabolism 148825325 Common - peptidyl-tRNA hydrolase CGSHiEE_01025 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 148826358 Common rpmH 50S ribosomal protein L34 CGSHiEE_06995 83 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 148825520 Common - hypothetical protein CGSHiEE_02140 17 COG4694 COG4694, Uncharacterized protein conserved in bacteria Function unknown 148825145 Common - hypothetical protein CGSHiEE_00085 44 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 148826175 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase CGSHiEE_05950 121 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 148826054 Common - bifunctional heptose 7-phosphate kinase/heptose 1-phosphate adenyltransferase CGSHiEE_05200 183 COG2870 RfaE, ADP-heptose synthase, bifunctional sugar kinase/adenylyltransferase Cell envelope biogenesis, outer membrane 148826501 Common - putative heme iron utilization protein CGSHiEE_07770 15 COG0748 HugZ, Putative heme iron utilization protein Inorganic ion transport and metabolism 148826592 Common ftsX membrane component of ABC transporter FtsEX CGSHiEE_08265 22 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 148826339 Common - hypothetical protein CGSHiEE_06870 3 None None None 148826004 Pathogen - hypothetical protein CGSHiEE_04905 1 None None None 148826636 Common - heat shock protein HtpX CGSHiEE_08525 190 COG0501 HtpX, Zn-dependent protease with chaperone function Posttranslational modification, protein turnover, chaperones 148826555 Common - 30S ribosomal protein S11 CGSHiEE_08060 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 148825477 Common yajC preprotein translocase subunit YajC CGSHiEE_01870 165 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 148826537 Common galM aldose 1-epimerase CGSHiEE_07970 88 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 148825368 Common - cytochrome C-type protein NapC CGSHiEE_01260 52 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 148825804 Common - hypothetical protein CGSHiEE_03775 109 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 148826741 Common - RNA polymerase sigma factor RpoE CGSHiEE_09100 137 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 148826273 Pathogen - hypothetical protein CGSHiEE_06490 1 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148825352 Common ispG 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase CGSHiEE_01180 28 COG3063 PilF, Tfp pilus assembly protein PilF Cell motility and secretion / Intracellular trafficking and secretion 148826102 Common argS arginyl-tRNA synthetase CGSHiEE_05515 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148826660 Common - hypothetical protein CGSHiEE_08655 97 COG2911 COG2911, Uncharacterized protein conserved in bacteria Function unknown 148825627 Common - iron(III) ABC transporter ATP-binding protein CGSHiEE_02795 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 148826454 Common - dinucleoside polyphosphate hydrolase CGSHiEE_07505 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 148825385 Common - Histidine Kinase CGSHiEE_01345 29 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148826221 Common - hypothetical protein CGSHiEE_06200 22 COG2926 COG2926, Uncharacterized protein conserved in bacteria Function unknown 148825884 Common - ABC transporter ATPase component CGSHiEE_04245 138 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 148826034 Pathogen - hypothetical protein CGSHiEE_05085 2 None None None 148826613 Common - preprotein translocase subunit SecB CGSHiEE_08390 108 COG1952 SecB, Preprotein translocase subunit SecB Intracellular trafficking and secretion 148826280 Common - ADP-heptose--lipooligosaccharide heptosyltransferase II CGSHiEE_06535 110 COG0859 RfaF, ADP-heptose:LPS heptosyltransferase Cell envelope biogenesis, outer membrane 148825508 Common - L-fuculokinase CGSHiEE_02045 176 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148826737 Common rseB periplasmic negative regulator of sigmaE CGSHiEE_09080 48 COG3026 RseB, Negative regulator of sigma E activity Signal transduction mechanisms 148825302 Common thiE thiamine-phosphate pyrophosphorylase CGSHiEE_00910 203 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 148825850 Common - probable periplasmic serine protease do/HhoA-like precursor CGSHiEE_04045 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 148826352 Common trmE tRNA modification GTPase TrmE CGSHiEE_06965 232 COG0486 ThdF, Predicted GTPase General function prediction only 148825859 Common metG methionyl-tRNA synthetase CGSHiEE_04120 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148826151 Common - putative translation initiation inhibitor, YjgF family protein CGSHiEE_05800 90 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 148825412 Common - putative 3-phenylpropionic acid transporter CGSHiEE_01510 75 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148825407 Common ruvC Holliday junction resolvase CGSHiEE_01485 195 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 148825457 Common - heme/hemopexin-binding protein A CGSHiEE_01735 56 COG3210 FhaB, Large exoproteins involved in heme utilization or adhesion Intracellular trafficking and secretion 148825586 Common - anaerobic C4-dicarboxylate transporter CGSHiEE_02555 112 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 148826068 Common mnmC 5-methylaminomethyl-2-thiouridine methyltransferase CGSHiEE_05310 16 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 148825895 Common - hypothetical protein CGSHiEE_04300 75 COG2983 COG2983, Uncharacterized conserved protein Function unknown 148825925 Common sbcB exonuclease I CGSHiEE_04490 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 148825699 Common - hypothetical protein CGSHiEE_03210 100 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 148825727 Common - predicted branched-chain amino acid permease CGSHiEE_03360 18 COG1687 AzlD, Predicted branched-chain amino acid permeases (azaleucine resistance) Amino acid transport and metabolism 148825561 Common rluD 23S rRNA pseudouridine synthase D CGSHiEE_02410 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 148826589 Common - cell division protein FtsY CGSHiEE_08250 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 148825764 Common modB molybdate ABC transporter permease protein CGSHiEE_03575 230 COG4149 ModC, ABC-type molybdate transport system, permease component Inorganic ion transport and metabolism 148825779 Common - HMW1A, high molecular weight adhesin 1 CGSHiEE_03650 151 None None None 148825836 Common - bicyclomycin/multidrug efflux system CGSHiEE_03955 208 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148825296 Common - rRNA methylase CGSHiEE_00880 107 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 148825621 Common - putative type I restriction-modification system, methyltransferase subunit CGSHiEE_02765 158 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 148826017 Common rpsO 30S ribosomal protein S15 CGSHiEE_04980 12 None None None 148825629 Pathogen - hypothetical protein CGSHiEE_02815 1 None None None 148825684 Common - hypothetical protein CGSHiEE_03135 56 COG2985 COG2985, Predicted permease General function prediction only 148825748 Common - hypothetical protein CGSHiEE_03485 25 COG3111 COG3111, Uncharacterized conserved protein Function unknown 148825678 Common - hypothetical protein CGSHiEE_03090 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 148826527 Common - YciI-like protein CGSHiEE_07920 66 COG2350 COG2350, Uncharacterized protein conserved in bacteria Function unknown 148825183 Common groEL chaperonin GroEL CGSHiEE_00275 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 148826045 Common - predicted threonine efflux protein CGSHiEE_05140 95 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 148826377 Common panF sodium/panthothenate symporter CGSHiEE_07090 159 COG4145 PanF, Na+/panthothenate symporter Coenzyme metabolism 148826452 Common - prolipoprotein diacylglyceryl transferase CGSHiEE_07495 208 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 148825168 Common - virulence-associated protein D CGSHiEE_00200 5 COG3309 VapD, Uncharacterized virulence-associated protein D Function unknown 148826219 Common - para-aminobenzoate synthase component I CGSHiEE_06190 221 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 148826721 Common - aspartate-semialdehyde dehydrogenase CGSHiEE_08980 200 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 148825524 Common - hypothetical protein CGSHiEE_02160 9 COG2832 COG2832, Uncharacterized protein conserved in bacteria Function unknown 148826691 Common ispF 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase CGSHiEE_08820 189 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 148826076 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase CGSHiEE_05350 237 COG0161 BioA, Adenosylmethionine-8-amino-7-oxononanoate aminotransferase Coenzyme metabolism 148826664 Common glpQ glycerophosphodiester phosphodiesterase CGSHiEE_08675 20 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 148825345 Common - ferredoxin, 2Fe-2S CGSHiEE_01145 110 COG0633 Fdx, Ferredoxin Energy production and conversion 148826407 Common - hypothetical protein CGSHiEE_07250 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 148826171 Common - phosphoenolpyruvate carboxylase CGSHiEE_05910 116 COG2855 COG2855, Predicted membrane protein Function unknown 148825807 Common - TldD CGSHiEE_03790 170 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 148825653 Common - probable N-acetylmuramoyl-L-alanine amidase AmiB precursor CGSHiEE_02965 127 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 148826446 Pathogen - hypothetical protein CGSHiEE_07465 1 None None None 148825496 Common - biotin--protein ligase CGSHiEE_01975 228 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 148825568 Common - transcriptional regulator CGSHiEE_02465 82 COG0271 BolA, Stress-induced morphogen (activity unknown) Signal transduction mechanisms 148825577 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase CGSHiEE_02510 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148825243 Common atpC F0F1 ATP synthase subunit epsilon CGSHiEE_00595 193 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 148825847 Common - predicted P-loop ATPase fused to an acetyltransferase CGSHiEE_04030 48 COG1444 COG1444, Predicted P-loop ATPase fused to an acetyltransferase General function prediction only 148826158 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase CGSHiEE_05835 151 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 148825370 Common napH quinol dehydrogenase membrane component CGSHiEE_01270 75 COG0348 NapH, Polyferredoxin Energy production and conversion 148825872 Common rbfA ribosome-binding factor A CGSHiEE_04185 176 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 148826061 Common - LicA CGSHiEE_05255 24 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 148826178 Common - single-stranded-DNA-specific exonuclease RecJ CGSHiEE_05965 192 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 148826500 Common - hypothetical protein CGSHiEE_07765 25 COG3681 COG3681, Uncharacterized conserved protein Function unknown 148826264 Common oppB oligopeptide permease ABC transporter membrane protein CGSHiEE_06435 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148825198 Common - tyrosine-specific transport protein 2 CGSHiEE_00350 32 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 148825731 Common - predicted allophanate hydrolase subunit 1 CGSHiEE_03390 99 COG2049 DUR1, Allophanate hydrolase subunit 1 Amino acid transport and metabolism 148826648 Common tig trigger factor CGSHiEE_08595 249 COG3276 SelB, Selenocysteine-specific translation elongation factor Translation, ribosomal structure and biogenesis 148825487 Common - polynucleotide phosphorylase/polyadenylase CGSHiEE_01930 242 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 148826196 Common - SAM-dependent methyltransferase CGSHiEE_06065 45 COG2933 COG2933, Predicted SAM-dependent methyltransferase General function prediction only 148826471 Common - DNA-binding response regulator in two-component regulatory system with ArcB or CpxA CGSHiEE_07610 217 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148825226 Common hslU ATP-dependent protease ATP-binding subunit CGSHiEE_00510 212 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 148825204 Common - hypothetical protein CGSHiEE_00400 82 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 148825150 Common - DNA-binding transcriptional regulator OxyR CGSHiEE_00110 190 COG0583 LysR, Transcriptional regulator Transcription 148825442 Common - uridine phosphorylase CGSHiEE_01660 79 COG2258 COG2258, Uncharacterized protein conserved in bacteria Function unknown 148825495 Common - inositol-5-monophosphate dehydrogenase CGSHiEE_01970 241 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 148825464 Common - hypothetical protein CGSHiEE_01780 67 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 148825232 Common - predicted phosphatase/phosphohexomutase CGSHiEE_00540 173 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 148826672 Common xerC site-specific tyrosine recombinase XerC CGSHiEE_08715 225 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 148825177 Common infA translation initiation factor IF-1 CGSHiEE_00245 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 148825977 Common - tRNA pseudouridine synthase C CGSHiEE_04770 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 148825310 Common - hypothetical protein CGSHiEE_00950 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 148825590 Common - N-acetylneuraminate lyase CGSHiEE_02575 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 148826601 Common rpmE 50S ribosomal protein L31 CGSHiEE_08330 25 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 148826023 Common rplT 50S ribosomal protein L20 CGSHiEE_05010 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 148826705 Common - putative HTH-type transcriptional regulator CGSHiEE_08900 5 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 148826021 Common - exodeoxyribonuclease V alpha chain CGSHiEE_05000 123 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 148826201 Common - 6-pyruvoyl tetrahydrobiopterin synthase CGSHiEE_06090 129 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 148826438 Common - hypothetical protein CGSHiEE_07425 210 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 148826490 Pathogen - CMP-neu5Ac--lipooligosaccharide alpha 2-3 sialyltransferase CGSHiEE_07715 4 None None None 148825584 Common - hypothetical protein CGSHiEE_02545 26 COG3055 COG3055, Uncharacterized protein conserved in bacteria Function unknown 148825976 Common - hypothetical protein CGSHiEE_04765 15 COG3140 COG3140, Uncharacterized protein conserved in bacteria Function unknown 148826051 Common - putative carbonic anhydrase CGSHiEE_05170 146 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 148825990 Common folE GTP cyclohydrolase I CGSHiEE_04835 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 148826558 Common secY preprotein translocase subunit SecY CGSHiEE_08075 238 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 148826313 Pathogen - hypothetical protein CGSHiEE_06710 1 None None None 148825391 Common - predicted primosomal replication protein N CGSHiEE_01395 6 COG3923 PriC, Primosomal replication protein N'' DNA replication, recombination, and repair 148826381 Common - 3-dehydroquinate dehydratase CGSHiEE_07110 169 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 148825279 Common - hypothetical protein CGSHiEE_00785 85 COG2961 ComJ, Protein involved in catabolism of external DNA General function prediction only 148825949 Common - putative prophage repressor CI CGSHiEE_04620 30 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 148825479 Common - hypothetical protein CGSHiEE_01890 206 COG0628 PerM, Predicted permease General function prediction only 148825377 Common - primosome assembly protein PriA CGSHiEE_01305 213 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 148826344 Common serB phosphoserine phosphatase CGSHiEE_06895 149 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 148826090 Pathogen - hypothetical protein CGSHiEE_05420 1 None None None 148825916 Common - phosphate regulon sensor protein PhoR CGSHiEE_04445 220 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 148825999 Common - RNA polymerase sigma factor CGSHiEE_04880 115 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 148826651 Common - DNA mismatch repair protein CGSHiEE_08610 202 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 148826388 Common - HIT-like protein CGSHiEE_07155 233 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 148826652 Common - lipoprotein CGSHiEE_08615 188 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 148826728 Common - adenylosuccinate lyase CGSHiEE_09025 227 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 148825592 Common nagA N-acetylglucosamine-6-phosphate deacetylase CGSHiEE_02585 119 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 148825901 Common pntA NAD(P) transhydrogenase subunit alpha CGSHiEE_04340 166 COG3288 PntA, NAD/NADP transhydrogenase alpha subunit Energy production and conversion 148825708 Common rimI ribosomal-protein-alanine N-acetyltransferase CGSHiEE_03265 172 COG0456 RimI, Acetyltransferases General function prediction only 148826106 Common - predicted Na+/H+ antiporter CGSHiEE_05535 45 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 148825346 Common - hypothetical protein CGSHiEE_01150 43 COG2975 COG2975, Uncharacterized protein conserved in bacteria Function unknown 148825216 Common - hypothetical protein CGSHiEE_00460 130 COG1609 PurR, Transcriptional regulators Transcription 148825802 Common - hypothetical protein CGSHiEE_03765 63 COG2823 OsmY, Predicted periplasmic or secreted lipoprotein General function prediction only 148825610 Pathogen - hypothetical protein CGSHiEE_02700 1 None None None 148826131 Common cca multifunctional tRNA nucleotidyl transferase/2'3'-cyclic phosphodiesterase/2'nucleotidase/phosphatase CGSHiEE_05680 194 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 148825435 Common - transcriptional repressor protein MetJ CGSHiEE_01625 31 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 148826323 Common pyrH uridylate kinase CGSHiEE_06770 188 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 148825152 Common greB transcription elongation factor GreB CGSHiEE_00120 186 COG0782 GreA, Transcription elongation factor Transcription 148826156 Common - 50S ribosomal protein L25 CGSHiEE_05825 27 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 148825386 Common recO DNA repair protein RecO CGSHiEE_01370 102 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 148826743 Common trkA potassium transporter peripheral membrane component CGSHiEE_09110 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 148825619 Common - putative type I site-specific restriction-modification system, S subunit CGSHiEE_02755 88 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 148826484 Pathogen - N-acetylneuraminic acid synthase-like protein CGSHiEE_07675 3 None None None 148826518 Pathogen - hypothetical protein CGSHiEE_07875 1 None None None 148825967 Common - universal stress protein UspE CGSHiEE_04710 50 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 148826147 Common - hypothetical protein CGSHiEE_05770 5 None None None 148825944 Common - hypothetical protein CGSHiEE_04595 25 COG0864 NikR, Predicted transcriptional regulators containing the CopG/Arc/MetJ DNA-binding domain and a metal-binding domain Transcription 148826115 Common - DNA repair protein RadA CGSHiEE_05590 216 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 148826245 Common - cell division protein FtsZ CGSHiEE_06330 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 148826226 Common - histidinol-phosphate aminotransferase CGSHiEE_06235 96 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 148825230 Common - S-ribosylhomocysteinase CGSHiEE_00530 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 148826564 Common rpsH 30S ribosomal protein S8 CGSHiEE_08105 238 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 148825721 Common - guanosine-3',5'-bis 3'-pyrophosphohydrolase CGSHiEE_03330 207 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148826173 Common - cytidylate kinase CGSHiEE_05930 6 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 148825821 Common - DNA replication initiation factor CGSHiEE_03870 123 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 148826318 Common nrfA cytochrome c nitrite reductase CGSHiEE_06735 40 COG3303 NrfA, Formate-dependent nitrite reductase, periplasmic cytochrome c552 subunit Inorganic ion transport and metabolism 148825631 Common - hypothetical protein CGSHiEE_02825 16 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 148826304 Common ligA NAD-dependent DNA ligase LigA CGSHiEE_06655 52 COG5007 COG5007, Predicted transcriptional regulator, BolA superfamily Transcription 148826594 Common - nicotinamide-nucleotide adenylyltransferase CGSHiEE_08285 7 COG2129 COG2129, Predicted phosphoesterases, related to the Icc protein General function prediction only 148825886 Common potB spermidine/putrescine ABC transporter membrane protein CGSHiEE_04255 214 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 148826638 Common - heat shock protein HtpX CGSHiEE_08535 94 COG2853 VacJ, Surface lipoprotein Cell envelope biogenesis, outer membrane 148825667 Common - Uxu operon regulator CGSHiEE_03035 123 COG2186 FadR, Transcriptional regulators Transcription 148826422 Common - glutaredoxin-related protein CGSHiEE_07345 7 COG4545 COG4545, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 148825983 Common - ClpXP protease specificity-enhancing factor CGSHiEE_04800 64 COG2969 SspB, Stringent starvation protein B General function prediction only 148825338 Common - hypothetical protein CGSHiEE_01110 175 COG1959 COG1959, Predicted transcriptional regulator Transcription 148825535 Common rplS 50S ribosomal protein L19 CGSHiEE_02240 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 148826539 Common - Xaa-Pro aminopeptidase CGSHiEE_07980 238 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 148826544 Common - argininosuccinate lyase CGSHiEE_08005 236 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 148826056 Common - Sodium/glutamate symport carrier protein CGSHiEE_05230 56 COG0786 GltS, Na+/glutamate symporter Amino acid transport and metabolism 148825354 Common - hypothetical protein CGSHiEE_01190 142 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 148825266 Common - putative deoxyribonuclease CGSHiEE_00720 238 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 148826368 Common - hypothetical protein CGSHiEE_07045 86 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 148825298 Common - ATP-dependent RNA helicase SrmB CGSHiEE_00890 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 148826361 Common recF recombination protein F CGSHiEE_07010 165 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 148826584 Common - aldolase CGSHiEE_08225 78 COG1830 FbaB, DhnA-type fructose-1,6-bisphosphate aldolase and related enzymes Carbohydrate transport and metabolism 148825758 Common - putative UDP-galactose--lipooligosaccharide galactosyltransferase CGSHiEE_03545 220 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148825364 Pathogen - CMP-neu5Ac--lipooligosaccharide alpha 2-3 sialyltransferase CGSHiEE_01240 4 None None None 148825422 Common - Type IV pilin subunit protein CGSHiEE_01560 4 COG4969 PilA, Tfp pilus assembly protein, major pilin PilA Cell motility and secretion / Intracellular trafficking and secretion 148826587 Common ftsX cell division protein FtsX CGSHiEE_08240 100 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 148825786 Common moaC molybdenum cofactor biosynthesis protein C CGSHiEE_03685 195 COG0315 MoaC, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 148825174 Common ksgA dimethyladenosine transferase CGSHiEE_00230 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 148825143 Common - elongation factor G CGSHiEE_00075 5 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 148826686 Common - iron-hydroxamate transporter permease subunit CGSHiEE_08795 43 None None None 148826036 Common - putative 5'(3')-deoxyribonucleotidase CGSHiEE_05095 5 COG4502 COG4502, Uncharacterized protein conserved in bacteria Function unknown 148825828 Common aceE pyruvate dehydrogenase subunit E1 CGSHiEE_03905 157 COG2609 AceE, Pyruvate dehydrogenase complex, dehydrogenase (E1) component Energy production and conversion 148826397 Common radC DNA repair protein RadC CGSHiEE_07200 179 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 148826282 Common - D-xylose transporter subunit CGSHiEE_06545 213 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 148826411 Common - hypothetical protein CGSHiEE_07270 6 COG4795 PulJ, Type II secretory pathway, component PulJ Intracellular trafficking and secretion 148826031 Common - DNA translocase FtsK CGSHiEE_05070 96 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 148826341 Common - hypothetical protein CGSHiEE_06880 74 COG0762 COG0762, Predicted integral membrane protein Function unknown 148826597 Common - hypothetical protein CGSHiEE_08300 230 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 148826689 Common ftsB cell divison protein FtsB CGSHiEE_08810 61 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 148826088 Common - hypothetical protein CGSHiEE_05410 31 COG3101 COG3101, Uncharacterized protein conserved in bacteria Function unknown 148825794 Common - hypothetical protein CGSHiEE_03725 62 COG3108 COG3108, Uncharacterized protein conserved in bacteria Function unknown 148826085 Common - Sel1-like repeat protein CGSHiEE_05395 109 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 148825817 Common - hypothetical protein CGSHiEE_03850 60 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 148825272 Common - fructose-specific PTS IIA/HPr components CGSHiEE_00750 124 COG4668 MtlA, Mannitol/fructose-specific phosphotransferase system, IIA domain Carbohydrate transport and metabolism 148825449 Common djlA Dna-J like membrane chaperone protein CGSHiEE_01695 74 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 148825810 Common - hypothetical protein CGSHiEE_03805 3 None None None 148826298 Common - superoxide dismutase (Mn) CGSHiEE_06625 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 148825488 Common - hypothetical protein CGSHiEE_01935 10 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 148825687 Common - penicillin-binding protein 2 CGSHiEE_03150 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 148825323 Common xseA exodeoxyribonuclease VII large subunit CGSHiEE_01015 57 COG2850 COG2850, Uncharacterized conserved protein Function unknown 148826246 Common - cell division protein FtsZ CGSHiEE_06345 69 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 148826429 Common glyS glycyl-tRNA synthetase subunit beta CGSHiEE_07380 32 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 148826071 Common - outer membrane-specific lipoprotein transporter subunit LolE CGSHiEE_05325 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 148825602 Common - cystathionine beta-lyase CGSHiEE_02660 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 148826466 Common glyA serine hydroxymethyltransferase CGSHiEE_07585 3 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 148825515 Common - probable D-methionine-binding lipoprotein MetQ CGSHiEE_02080 100 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 148826101 Common pgi glucose-6-phosphate isomerase CGSHiEE_05500 4 None None None 148825931 Common valS valyl-tRNA synthetase CGSHiEE_04530 2 None None None 148825762 Common - transcriptional regulator ModE CGSHiEE_03565 84 COG2005 ModE, N-terminal domain of molybdenum-binding protein General function prediction only 148825959 Common - predicted phage anti-repressor protein CGSHiEE_04670 16 COG3561 COG3561, Phage anti-repressor protein Transcription 148826390 Common - beta-hexosaminidase CGSHiEE_07165 177 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 148825563 Common - formate acetyltransferase CGSHiEE_02440 58 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 148826524 Common mtgA monofunctional biosynthetic peptidoglycan transglycosylase CGSHiEE_07905 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 148825493 Common - polynucleotide phosphorylase/polyadenylase CGSHiEE_01960 95 COG2962 RarD, Predicted permeases General function prediction only 148826326 Common rnhB ribonuclease HII CGSHiEE_06785 239 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 148825775 Common - hypothetical protein CGSHiEE_03630 16 COG3110 COG3110, Uncharacterized protein conserved in bacteria Function unknown 148826286 Common - hypothetical protein CGSHiEE_06565 4 None None None 148826210 Common artP arginine transporter ATP-binding subunit CGSHiEE_06145 249 COG4161 ArtP, ABC-type arginine transport system, ATPase component Amino acid transport and metabolism 148825897 Common - glycogen branching enzyme CGSHiEE_04320 162 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 148825962 Pathogen - integrase/recombinase CGSHiEE_04685 1 None None None 148825672 Common - D-mannonate oxidoreductase CGSHiEE_03060 236 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148826416 Common - cytochrome C-type biogenesis protein CGSHiEE_07295 88 COG4235 COG4235, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 148825403 Common - transposase CGSHiEE_01465 15 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 148826580 Common - hypothetical protein CGSHiEE_08195 68 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 148825957 Pathogen - hypothetical protein CGSHiEE_04660 2 None None None 148826550 Common - hypothetical protein CGSHiEE_08035 102 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 148825227 Common - ATP-dependent protease peptidase subunit CGSHiEE_00515 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 148826430 Pathogen - hypothetical protein CGSHiEE_07385 1 None None None 148825416 Common - hypothetical protein CGSHiEE_01530 126 COG1678 COG1678, Putative transcriptional regulator Transcription 148826020 Common - hypothetical protein CGSHiEE_04995 17 COG3120 COG3120, Uncharacterized protein conserved in bacteria Function unknown 148826492 Common - pyridoxamine 5'-phosphate oxidase CGSHiEE_07725 132 COG0259 PdxH, Pyridoxamine-phosphate oxidase Coenzyme metabolism 148825806 Common - hypothetical protein CGSHiEE_03785 209 COG0313 COG0313, Predicted methyltransferases General function prediction only 148826605 Common - phosphoribosylformylglycinamidine synthase CGSHiEE_08350 98 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148825513 Common - glp protein CGSHiEE_02070 105 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 148825190 Common - urease accessory protein CGSHiEE_00310 152 COG0378 HypB, Ni2+-binding GTPase involved in regulation of expression and maturation of urease and hydrogenase Posttranslational modification, protein turnover, chaperones / Transcription 148826234 Common - hypothetical protein CGSHiEE_06275 4 None None None 148826677 Common glpQ glycerophosphodiester phosphodiesterase CGSHiEE_08750 90 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 148825263 Common - pyrimidine regulatory protein PyrR CGSHiEE_00705 185 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 148825875 Common queF 7-cyano-7-deazaguanine reductase CGSHiEE_04200 86 COG2904 COG2904, Uncharacterized protein conserved in bacteria Function unknown 148826663 Common - hypothetical protein CGSHiEE_08670 26 COG2503 COG2503, Predicted secreted acid phosphatase General function prediction only 148826266 Common - oligopeptide transport ATP-binding protein CGSHiEE_06445 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 148826187 Common - acetate kinase CGSHiEE_06020 161 COG0282 ackA, Acetate kinase Energy production and conversion 148825331 Common - probable ATP-dependent helicase CGSHiEE_01065 154 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 148825241 Common - F0F1 ATP synthase subunit gamma CGSHiEE_00585 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 148826312 Common - probable cytochrome oxidase subunit II CGSHiEE_06705 154 COG1294 AppB, Cytochrome bd-type quinol oxidase, subunit 2 Energy production and conversion 148826010 Common rrmJ 23S rRNA methyltransferase J CGSHiEE_04945 97 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 148826153 Common - cobalt transport protein CbiM CGSHiEE_05810 131 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 148825239 Common - F0F1 ATP synthase subunit delta CGSHiEE_00575 147 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 148825777 Common - HMW1C, putative glycosyltransferase involved in glycosylation of HMW1A and HMW2A CGSHiEE_03640 18 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 148825834 Common - predicted membrane protein CGSHiEE_03945 133 COG2860 COG2860, Predicted membrane protein Function unknown 148825219 Common rbsC ribose ABC transporter permease protein CGSHiEE_00475 165 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148825623 Common - heat shock protein 90 CGSHiEE_02775 151 COG0326 HtpG, Molecular chaperone, HSP90 family Posttranslational modification, protein turnover, chaperones 148825534 Common trmD tRNA (guanine-N(1)-)-methyltransferase CGSHiEE_02235 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 148826435 Common leuS leucyl-tRNA synthetase CGSHiEE_07410 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148825570 Common - glutathione reductase CGSHiEE_02475 247 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 148825923 Common - ferritin CGSHiEE_04480 85 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 148825688 Common - rod shape-determining protein CGSHiEE_03155 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 148825181 Common rpsR 30S ribosomal protein S18 CGSHiEE_00265 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 148826575 Common rplB 50S ribosomal protein L2 CGSHiEE_08160 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 148826374 Common prmA ribosomal protein L11 methyltransferase CGSHiEE_07075 174 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 148825746 Common - glucose-specific PTS system component CGSHiEE_03475 60 COG2190 NagE, Phosphotransferase system IIA components Carbohydrate transport and metabolism 148826254 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase CGSHiEE_06385 213 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 148825973 Common - aspartate-semialdehyde dehydrogenase CGSHiEE_04750 119 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 148826206 Common dppD dipeptide transporter ATP-binding subunit CGSHiEE_06125 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148825166 Common - glucose-6-phosphate 1-dehydrogenase CGSHiEE_00190 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 148825607 Common znuA high-affinity zinc transporter periplasmic component CGSHiEE_02685 182 COG1179 COG1179, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 1 Coenzyme metabolism 148825612 Common - predicted methyltransferase CGSHiEE_02720 88 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 148826616 Common - export protein SecB CGSHiEE_08405 241 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 148826723 Common - cytochrome C-like protein CGSHiEE_08990 56 COG3005 TorC, Nitrate/TMAO reductases, membrane-bound tetraheme cytochrome c subunit Energy production and conversion 148825763 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase CGSHiEE_03570 150 COG0725 ModA, ABC-type molybdate transport system, periplasmic component Inorganic ion transport and metabolism 148826674 Common - xanthine-guanine phosphoribosyltransferase CGSHiEE_08725 72 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 148825942 Common - dihydroorotate dehydrogenase 2 CGSHiEE_04585 175 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 148825365 Common - UDP-glucose 4-epimerase CGSHiEE_01245 232 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 148825290 Common nudC NADH pyrophosphatase CGSHiEE_00840 211 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 148825373 Common - NapD CGSHiEE_01285 16 COG3062 NapD, Uncharacterized protein involved in formation of periplasmic nitrate reductase Inorganic ion transport and metabolism 148826062 Common - lic-1 operon protein CGSHiEE_05260 7 None None None 148826443 Common rpsB 30S ribosomal protein S2 CGSHiEE_07450 220 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 148826078 Common - glycerate dehydrogenase CGSHiEE_05360 231 COG1052 LdhA, Lactate dehydrogenase and related dehydrogenases Energy production and conversion / Coenzyme metabolism / General function prediction only 148826525 Common - Trp operon repressor CGSHiEE_07910 21 COG2973 TrpR, Trp operon repressor Transcription 148826725 Common glmU bifunctional N-acetylglucosamine-1-phosphate uridyltransferase/glucosamine-1-phosphate acetyltransferase CGSHiEE_09010 231 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 148825654 Common - hypothetical protein CGSHiEE_02970 207 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 148825887 Common potA putrescine/spermidine ABC transporter ATPase protein CGSHiEE_04260 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 148825490 Common - branched-chain amino acid transport system II carrier protein CGSHiEE_01945 50 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 148825827 Common - dihydrolipoamide acetyltransferase CGSHiEE_03900 199 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 148825489 Common - hypothetical protein CGSHiEE_01940 30 COG2731 EbgC, Beta-galactosidase, beta subunit Carbohydrate transport and metabolism 148826692 Common - D-tyrosyl-tRNA deacylase CGSHiEE_08825 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 148826756 Common - predicted membrane protein CGSHiEE_09195 50 COG1288 COG1288, Predicted membrane protein Function unknown 148826703 Common - hemoglobin-binding protein CGSHiEE_08890 48 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 148825281 Common - competence protein A CGSHiEE_00795 4 COG4972 PilM, Tfp pilus assembly protein, ATPase PilM Cell motility and secretion / Intracellular trafficking and secretion 148825501 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase CGSHiEE_02000 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 148825439 Common - acyl-CoA thioester hydrolase YfbB CGSHiEE_01645 57 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148826180 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase CGSHiEE_05975 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 148825679 Common - exonuclease III CGSHiEE_03095 197 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 148825716 Common - haloacid dehalogenase-like protein CGSHiEE_03305 130 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 148825844 Common - hypothetical protein CGSHiEE_04015 75 COG3093 VapI, Plasmid maintenance system antidote protein General function prediction only 148825668 Common - zinc-type alcohol dehydrogenase CGSHiEE_03040 213 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 148825349 Pathogen - hypothetical protein CGSHiEE_01165 1 None None None 148826126 Common - hypothetical protein CGSHiEE_05645 62 COG3220 COG3220, Uncharacterized protein conserved in bacteria Function unknown 148826465 Common glyA serine hydroxymethyltransferase CGSHiEE_07580 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 148826292 Common - cytochrome C-type biogenesis protein CGSHiEE_06595 146 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 148826716 Common - ATP-dependent DNA helicase CGSHiEE_08955 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 148825599 Common - inorganic pyrophosphatase CGSHiEE_02645 186 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 148825734 Common - argininosuccinate synthase CGSHiEE_03415 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 148826195 Common cysB transcriptional regulator CysB CGSHiEE_06060 206 COG0045 SucC, Succinyl-CoA synthetase, beta subunit Energy production and conversion 148825420 Common - N-acetyl-anhydromuranmyl-L-alanine amidase CGSHiEE_01550 107 COG3023 AmpD, Negative regulator of beta-lactamase expression Defense mechanisms 148825580 Common - putative 4'-phosphopantetheinyl transferase CGSHiEE_02525 17 COG2091 Sfp, Phosphopantetheinyl transferase Coenzyme metabolism 148826541 Common alaS alanyl-tRNA synthetase CGSHiEE_07990 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148825529 Common aroB 3-dehydroquinate synthase CGSHiEE_02200 207 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 148826008 Common - dihydropteroate synthase CGSHiEE_04925 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 148826204 Common uvrD DNA-dependent helicase II CGSHiEE_06105 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 148825601 Common - uridine kinase CGSHiEE_02655 50 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 148825788 Common - molybdopterin converting factor subunit 2 CGSHiEE_03695 160 COG0314 MoaE, Molybdopterin converting factor, large subunit Coenzyme metabolism 148825406 Common - hypothetical protein CGSHiEE_01480 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 148825141 Common - elongation factor G CGSHiEE_00065 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 148825321 Common - cyclic 3',5'-adenosine monophosphate phosphodiesterase CGSHiEE_01005 113 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 148825718 Common - hypothetical protein CGSHiEE_03315 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 148826495 Common - 23S rRNA (guanosine-2'-O-)-methyltransferase CGSHiEE_07740 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 148825662 Common - 3-deoxy-manno-octulosonate cytidylyltransferase CGSHiEE_03010 148 COG1212 KdsB, CMP-2-keto-3-deoxyoctulosonic acid synthetase Cell envelope biogenesis, outer membrane 148826073 Common - biotin synthesis protein CGSHiEE_05335 24 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148825796 Common - carboxy-terminal protease CGSHiEE_03735 222 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148825149 Common - hypothetical protein CGSHiEE_00105 116 COG0678 AHP1, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148825934 Common - hypothetical protein CGSHiEE_04545 31 COG4185 COG4185, Uncharacterized protein conserved in bacteria Function unknown 148826395 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase CGSHiEE_07190 182 COG0756 Dut, dUTPase Nucleotide transport and metabolism 148825981 Common - exodeoxyribonuclease VII small subunit CGSHiEE_04790 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 148825175 Common - lipooligosaccharide glycosyl transferase G CGSHiEE_00235 99 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148825205 Common - hypothetical protein CGSHiEE_00405 68 COG1972 NupC, Nucleoside permease Nucleotide transport and metabolism 148825144 Common - hypothetical protein CGSHiEE_00080 36 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 148826602 Pathogen - hypothetical protein CGSHiEE_08335 1 None None None 148825480 Common - putative arsenate reductase CGSHiEE_01895 115 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 148826276 Common - D-xylose ABC transporter permease protein CGSHiEE_06515 110 COG4214 XylH, ABC-type xylose transport system, permease component Carbohydrate transport and metabolism 148826412 Common - hypothetical protein CGSHiEE_07275 4 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 148826060 Common mnmC 5-methylaminomethyl-2-thiouridine methyltransferase CGSHiEE_05250 88 COG4121 COG4121, Uncharacterized conserved protein Function unknown 148826426 Common - major phage capsid protein precursor CGSHiEE_07365 19 None None None 148826248 Common murC UDP-N-acetylmuramate--L-alanine ligase CGSHiEE_06355 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 148826642 Common clpP ATP-dependent Clp protease proteolytic subunit CGSHiEE_08555 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148826177 Common - single-stranded-DNA-specific exonuclease RecJ CGSHiEE_05960 30 None None None 148826335 Common - anaerobic dimethyl sulfoxide reductase chain C CGSHiEE_06850 25 COG3302 DmsC, DMSO reductase anchor subunit General function prediction only 148825820 Common - DNA replication initiation factor CGSHiEE_03865 191 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 148826649 Common - selenocysteine synthase CGSHiEE_08600 72 COG1921 SelA, Selenocysteine synthase [seryl-tRNASer selenium transferase] Amino acid transport and metabolism 148825781 Common - transposase CGSHiEE_03660 60 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 148826316 Common - ATP-dependent RNA helicase HrpA CGSHiEE_06725 131 COG1643 HrpA, HrpA-like helicases DNA replication, recombination, and repair 148825992 Common - molybdopterin biosynthesis protein MoeB CGSHiEE_04845 223 COG0476 ThiF, Dinucleotide-utilizing enzymes involved in molybdopterin and thiamine biosynthesis family 2 Coenzyme metabolism 148825434 Common - L-serine deaminase CGSHiEE_01620 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 148825867 Common infB translation initiation factor IF-2 CGSHiEE_04160 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 148825756 Common - hypothetical protein CGSHiEE_03525 61 COG1434 COG1434, Uncharacterized conserved protein Function unknown 148825559 Common - Na(+)-translocating NADH-quinone reductase subunit F CGSHiEE_02390 19 COG2991 COG2991, Uncharacterized protein conserved in bacteria Function unknown 148826424 Common glyS glycyl-tRNA synthetase subunit beta CGSHiEE_07355 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 148825736 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase CGSHiEE_03425 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 148825390 Common - elongation factor P CGSHiEE_01390 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 148826364 Common - isopropylmalate isomerase large subunit CGSHiEE_07025 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 148826542 Common - carbon storage regulator CGSHiEE_07995 84 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 148826736 Pathogen - hypothetical protein CGSHiEE_09065 1 None None None 148825889 Common - peptidase T CGSHiEE_04270 127 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 148825303 Common - phosphomethylpyrimidine kinase CGSHiEE_00915 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 148825783 Common - KpsF CGSHiEE_03670 162 COG0794 GutQ, Predicted sugar phosphate isomerase involved in capsule formation Cell envelope biogenesis, outer membrane 148826450 Common secA preprotein translocase subunit SecA CGSHiEE_07485 216 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 148826378 Common panF sodium/panthothenate symporter CGSHiEE_07095 17 COG3924 COG3924, Predicted membrane protein Function unknown 148825379 Common - primosome assembly protein PriA CGSHiEE_01315 188 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 148826331 Common - hypothetical protein CGSHiEE_06820 5 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 148826567 Common rplX 50S ribosomal protein L24 CGSHiEE_08120 208 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 148825552 Common - Na(+)-translocating NADH-quinone reductase subunit A CGSHiEE_02355 42 COG1726 NqrA, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrA Energy production and conversion 148826134 Common - ribose-phosphate pyrophosphokinase CGSHiEE_05695 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 148825543 Common - flavodoxin FldA CGSHiEE_02300 74 COG0716 FldA, Flavodoxins Energy production and conversion 148825387 Common - opacity associated protein OapB CGSHiEE_01375 3 None None None 148826560 Common rpmD 50S ribosomal protein L30 CGSHiEE_08085 141 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 148825540 Common - potassium efflux protein KefA CGSHiEE_02275 211 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 148826577 Common rplD 50S ribosomal protein L4 CGSHiEE_08170 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 148825655 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase CGSHiEE_02975 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 148825952 Common - hypothetical protein CGSHiEE_04635 6 COG3422 COG3422, Uncharacterized conserved protein Function unknown 148825993 Common - dsDNA-mimic protein CGSHiEE_04850 18 COG3099 COG3099, Uncharacterized protein conserved in bacteria Function unknown 148826170 Common - ABC-type transport system, ATPase component, involved in antimicrobial peptide resistance CGSHiEE_05905 248 COG4167 SapF, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 148826224 Common - Outer membrane protein P5 CGSHiEE_06225 144 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 148826512 Common - hypothetical protein CGSHiEE_07835 62 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 148825646 Common - nucleotidyltransferase CGSHiEE_02920 26 None None None 148825274 Common fruK 1-phosphofructokinase CGSHiEE_00760 68 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 148825158 Pathogen - hypothetical protein CGSHiEE_00150 1 None None None 148825217 Common - ribokinase CGSHiEE_00465 208 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148826043 Common pheS phenylalanyl-tRNA synthetase subunit alpha CGSHiEE_05130 40 COG0633 Fdx, Ferredoxin Energy production and conversion 148825709 Common - formate dehydrogenase accessory protein FdhE CGSHiEE_03270 41 COG3058 FdhE, Uncharacterized protein involved in formate dehydrogenase formation Posttranslational modification, protein turnover, chaperones 148825283 Common - competence protein C CGSHiEE_00805 4 None None None 148825702 Common - autonomous glycyl radical cofactor GrcA CGSHiEE_03225 52 COG3445 COG3445, Acid-induced glycyl radical enzyme General function prediction only 148826516 Common - nucleoid-associated protein NdpA CGSHiEE_07865 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148825237 Common - F0F1 ATP synthase subunit C CGSHiEE_00565 125 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 148826549 Common - predicted permease CGSHiEE_08030 43 COG0730 COG0730, Predicted permeases General function prediction only 148826394 Common slmA nucleoid occlusion protein CGSHiEE_07185 72 COG1309 AcrR, Transcriptional regulator Transcription 148825229 Common aphA acid phosphatase/phosphotransferase CGSHiEE_00525 87 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 148826406 Common - formamidopyrimidine-DNA glycosylase CGSHiEE_07245 225 COG1985 RibD, Pyrimidine reductase, riboflavin biosynthesis Coenzyme metabolism 148826141 Common - riboflavin synthase subunit alpha CGSHiEE_05740 232 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 148825309 Common - transcriptional regulatory protein CGSHiEE_00945 172 COG3283 TyrR, Transcriptional regulator of aromatic amino acids metabolism Transcription / Amino acid transport and metabolism 148825314 Common - pyridoxamine kinase CGSHiEE_00970 72 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 148825521 Common - hypothetical protein CGSHiEE_02145 92 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 148826517 Pathogen - hypothetical protein CGSHiEE_07870 1 None None None 148826379 Common - acetyl-CoA carboxylase biotin carboxylase subunit CGSHiEE_07100 234 COG0439 AccC, Biotin carboxylase Lipid metabolism 148825413 Common - pyrroline-5-carboxylate reductase CGSHiEE_01515 216 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 148825968 Common - universal stress protein UspE CGSHiEE_04715 11 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 148826053 Pathogen - ABC transporter ATPase component CGSHiEE_05195 1 None None None 148826321 Common pyrH uridylate kinase CGSHiEE_06760 228 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 148825458 Common - heme/hemopexin-binding protein B CGSHiEE_01740 66 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 148826091 Pathogen - hypothetical protein CGSHiEE_05425 2 None None None 148825594 Common rnhA ribonuclease H CGSHiEE_02595 168 COG0328 RnhA, Ribonuclease HI DNA replication, recombination, and repair 148825980 Common - exodeoxyribonuclease VII small subunit CGSHiEE_04785 108 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 148826123 Pathogen - putative ABC-type chelated iron transport system, permease component CGSHiEE_05630 1 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 148825857 Common - hypothetical protein CGSHiEE_04100 35 COG2242 CobL, Precorrin-6B methylase 2 Coenzyme metabolism 148826162 Common - transposase CGSHiEE_05855 6 None None None 148825813 Common - pyridoxine biosynthesis protein CGSHiEE_03820 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 148826461 Pathogen - hypothetical protein CGSHiEE_07560 1 None None None 148825447 Common rph ribonuclease PH CGSHiEE_01685 185 COG0689 Rph, RNase PH Translation, ribosomal structure and biogenesis 148825507 Common - L-fuculose phosphate aldolase CGSHiEE_02040 30 COG4154 FucU, Fucose dissimilation pathway protein FucU Carbohydrate transport and metabolism 148825574 Pathogen - hypothetical protein CGSHiEE_02495 1 None None None 148825451 Common - RNA polymerase factor sigma-32 CGSHiEE_01705 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 148826625 Common - prolyl-tRNA synthetase CGSHiEE_08470 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148825587 Common - N-acetylmannosamine-6-phosphate 2-epimerase CGSHiEE_02560 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 148826324 Common - UDP-N-acetylglucosamine acyltransferase CGSHiEE_06775 154 COG1043 LpxA, Acyl- acyl carrier protein 148826353 Common - putative inner membrane protein translocase component YidC CGSHiEE_06970 214 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 148826751 Common def peptide deformylase CGSHiEE_09150 10 COG3070 TfoX, Regulator of competence-specific genes Transcription 148826745 Common def peptide deformylase CGSHiEE_09120 215 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 148825694 Common - citrate lyase ligase CGSHiEE_03185 25 COG3053 CitC, Citrate lyase synthetase Energy production and conversion 148825635 Common - homoserine kinase CGSHiEE_02845 129 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 148826583 Common - autoinducer-2 (AI-2) kinase CGSHiEE_08220 49 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148825261 Common - pyrimidine regulatory protein PyrR CGSHiEE_00695 109 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 148825987 Common metF 5,10-methylenetetrahydrofolate reductase CGSHiEE_04820 143 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 148826268 Common - GTPase EngB CGSHiEE_06465 203 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 148826679 Common - anaerobic glycerol-3-phosphate dehydrogenase subunit B CGSHiEE_08760 32 COG3075 GlpB, Anaerobic glycerol-3-phosphate dehydrogenase Amino acid transport and metabolism 148826027 Common - predicted serine/threonine protein phosphatase family protein CGSHiEE_05050 9 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 148825172 Common apaH diadenosine tetraphosphatase CGSHiEE_00220 90 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 148826220 Common - hypothetical protein CGSHiEE_06195 18 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 148826111 Common - recombination factor protein RarA CGSHiEE_05570 238 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 148826116 Common - hypothetical protein CGSHiEE_05595 57 COG3025 COG3025, Uncharacterized conserved protein Function unknown 148826019 Common - 3-hydroxydecanoyl-ACP dehydratase CGSHiEE_04990 98 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 148825698 Common - CitXG CGSHiEE_03205 46 COG1767 CitG, Triphosphoribosyl-dephospho-CoA synthetase Coenzyme metabolism 148826189 Common - hypothetical protein CGSHiEE_06030 62 COG2840 COG2840, Uncharacterized protein conserved in bacteria Function unknown 148825221 Common - Ribose transport permease protein CGSHiEE_00485 44 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 148825950 Pathogen - hypothetical protein CGSHiEE_04625 1 None None None 148825336 Common tolB translocation protein TolB CGSHiEE_01090 165 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 148826508 Common - hypothetical protein CGSHiEE_07815 23 COG3085 COG3085, Uncharacterized protein conserved in bacteria Function unknown 148826012 Common - D-alanyl-D-alanine carboxypeptidase/endopeptidase CGSHiEE_04955 98 COG2027 DacB, D-alanyl-D-alanine carboxypeptidase (penicillin-binding protein 4) Cell envelope biogenesis, outer membrane 148825532 Common rpsP 30S ribosomal protein S16 CGSHiEE_02225 210 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 148825995 Common - conserved hypothetical cytochrome c-type biogenesis protein CGSHiEE_04860 83 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 148826712 Common aroE shikimate 5-dehydrogenase CGSHiEE_08935 129 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148826504 Pathogen - hypothetical protein CGSHiEE_07795 1 None None None 148826593 Common ribB 3,4-dihydroxy-2-butanone 4-phosphate synthase CGSHiEE_08270 229 COG0108 RibB, 3,4-dihydroxy-2-butanone 4-phosphate synthase Coenzyme metabolism 148826485 Common - putative polysaccharide polymerase CGSHiEE_07680 12 None None None 148826522 Common - fumarate reductase subunit C CGSHiEE_07895 23 COG3029 FrdC, Fumarate reductase subunit C Energy production and conversion 148825692 Common lipB lipoyltransferase CGSHiEE_03175 169 COG0321 LipB, Lipoate-protein ligase B Coenzyme metabolism 148825773 Common - Na(+)-translocating NADH-quinone reductase subunit E CGSHiEE_03620 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 148826003 Common - hypothetical protein CGSHiEE_04900 108 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148826384 Common - naphthoate synthase CGSHiEE_07125 4 None None None 148826294 Common - heme exporter protein D CGSHiEE_06605 4 COG3114 CcmD, Heme exporter protein D Intracellular trafficking and secretion 148826749 Pathogen - hypothetical protein CGSHiEE_09140 1 None None None 148826307 Common - probable amino-acid ABC transporter ATP-binding protein CGSHiEE_06680 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 148826607 Common - LexA repressor CGSHiEE_08360 174 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 148825195 Common rpsU 30S ribosomal protein S21 CGSHiEE_00335 122 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 148825555 Common - Na(+)-translocating NADH-quinone reductase subunit D CGSHiEE_02370 76 COG1347 NqrD, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrD Energy production and conversion 148826434 Common holA DNA polymerase III subunit delta CGSHiEE_07405 22 COG2980 RlpB, Rare lipoprotein B Cell envelope biogenesis, outer membrane 148825401 Common - transcriptional regulatory protein CGSHiEE_01455 33 COG2932 COG2932, Predicted transcriptional regulator Transcription 148826418 Pathogen - hypothetical protein CGSHiEE_07325 1 None None None 148826212 Common - arginine transporter permease subunit ArtQ CGSHiEE_06155 172 COG4215 ArtQ, ABC-type arginine transport system, permease component Amino acid transport and metabolism 148825686 Common - hypothetical protein CGSHiEE_03145 165 COG1576 COG1576, Uncharacterized conserved protein Function unknown 148826459 Common - predicted cation/multidrug efflux pump CGSHiEE_07540 179 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 148825418 Common lnt apolipoprotein N-acyltransferase CGSHiEE_01540 166 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 148825192 Common aspA aspartate ammonia-lyase CGSHiEE_00320 218 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 148825463 Pathogen - hypothetical protein CGSHiEE_01775 1 None None None 148825375 Common - hypothetical protein CGSHiEE_01295 25 COG3171 COG3171, Uncharacterized protein conserved in bacteria Function unknown 148825754 Common - leucyl aminopeptidase CGSHiEE_03515 107 COG0795 COG0795, Predicted permeases General function prediction only 148826494 Common - hypothetical protein CGSHiEE_07735 201 COG0557 VacB, Exoribonuclease R Transcription 148826182 Common - malate dehydrogenase CGSHiEE_05985 191 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 148825357 Common - iron (chelated) transporter ATP-binding protein CGSHiEE_01205 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 148825880 Common - hypothetical protein CGSHiEE_04225 23 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 148825972 Common trpA tryptophan synthase subunit alpha CGSHiEE_04745 212 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 148826038 Common - lipoprotein CGSHiEE_05105 134 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 148825582 Common - HflC CGSHiEE_02535 188 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 148826128 Common - conserved hypothetical phosphate transport regulator CGSHiEE_05665 39 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 148825842 Common - hypothetical protein CGSHiEE_04005 28 COG3683 COG3683, ABC-type uncharacterized transport system, periplasmic component General function prediction only 148825675 Common - hypothetical protein CGSHiEE_03075 18 COG3054 COG3054, Predicted transcriptional regulator General function prediction only 148825869 Common - hypothetical protein CGSHiEE_04170 19 None None None 148825714 Common - formate dehydrogenase accessory protein CGSHiEE_03295 136 COG1526 FdhD, Uncharacterized protein required for formate dehydrogenase activity Energy production and conversion 148825674 Common - hypothetical protein CGSHiEE_03070 105 COG2824 PhnA, Uncharacterized Zn-ribbon-containing protein involved in phosphonate metabolism Inorganic ion transport and metabolism 148826439 Common - protective surface antigen D15 CGSHiEE_07430 161 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 148826714 Common coaD phosphopantetheine adenylyltransferase CGSHiEE_08945 209 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 148825669 Common - putative TRAP-type C4-dicarboxylate transport system, small permease component CGSHiEE_03045 60 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 148825340 Common - scaffold protein CGSHiEE_01120 153 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 148826478 Common obgE GTPase ObgE CGSHiEE_07645 249 COG0536 Obg, Predicted GTPase General function prediction only 148825890 Common - cytidine deaminase CGSHiEE_04275 36 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 148825136 Common cpdB bifunctional 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase periplasmic precursor protein CGSHiEE_00040 125 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 148826055 Common - DNA topoisomerase IV subunit B CGSHiEE_05215 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 148826064 Common - hypothetical protein CGSHiEE_05290 74 COG0778 NfnB, Nitroreductase Energy production and conversion 148826094 Common prfA peptide chain release factor 1 CGSHiEE_05440 7 None None None 148826193 Common - hypothetical protein CGSHiEE_06050 230 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 148826618 Common - dihydroxy-acid dehydratase CGSHiEE_08425 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 148825258 Common - ATP-dependent proteinase CGSHiEE_00680 215 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 148825233 Common - S-ribosylhomocysteinase CGSHiEE_00545 8 None None None 148825328 Common - long-chain-fatty-acid--CoA ligase CGSHiEE_01050 223 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148825609 Common - possible SAM-dependent methyltransferase CGSHiEE_02695 162 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 148826696 Common - hypothetical protein CGSHiEE_08855 11 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 148825625 Common - succinyl-diaminopimelate desuccinylase CGSHiEE_02785 218 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 148826573 Common rplV 50S ribosomal protein L22 CGSHiEE_08150 218 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 148826302 Common - conserved ABC-type transport system protein CGSHiEE_06645 69 COG2854 Ttg2D, ABC-type transport system involved in resistance to organic solvents, auxiliary component Secondary metabolites biosynthesis, transport, and catabolism 148826694 Common - flavodoxin CGSHiEE_08835 20 COG3074 COG3074, Uncharacterized protein conserved in bacteria Function unknown 148826310 Pathogen - hypothetical protein CGSHiEE_06695 1 None None None 148825725 Common - transcriptional activator CGSHiEE_03350 189 COG0583 LysR, Transcriptional regulator Transcription 148825292 Common - disulfide bond formation protein B CGSHiEE_00850 53 COG1495 DsbB, Disulfide bond formation protein DsbB Posttranslational modification, protein turnover, chaperones 148825680 Common - hypothetical protein CGSHiEE_03100 7 None None None 148826733 Pathogen - predicted chloride channel protein CGSHiEE_09050 1 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 148826058 Common grxA glutaredoxin 1 CGSHiEE_05240 54 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 148825164 Pathogen - hypothetical protein CGSHiEE_00180 1 None None None 148826661 Common - exopolyphosphatase CGSHiEE_08660 179 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 148826441 Common lpxD UDP-3-O-[3-hydroxymyristoyl] glucosamine N-acyltransferase CGSHiEE_07440 173 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 148826499 Common - DNA polymerase I CGSHiEE_07760 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 148826256 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase CGSHiEE_06395 21 COG3116 FtsL, Cell division protein Cell division and chromosome partitioning 148825825 Pathogen - adenine phosphoribosyltransferase CGSHiEE_03890 1 None None None 148825427 Common - transcriptional repressor protein MetJ CGSHiEE_01585 23 COG3060 MetJ, Transcriptional regulator of met regulon Transcription / Amino acid transport and metabolism 148825793 Common - hypothetical protein CGSHiEE_03720 74 COG2989 COG2989, Uncharacterized protein conserved in bacteria Function unknown 148825335 Common tolA cell envelope integrity inner membrane protein TolA CGSHiEE_01085 19 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 148825649 Common ppnK inorganic polyphosphate/ATP-NAD kinase CGSHiEE_02935 239 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 148825738 Common - hypothetical protein CGSHiEE_03435 166 COG0316 IscA, Uncharacterized conserved protein Function unknown 148826403 Common - diaminobutyrate--2-oxoglutarate aminotransferase CGSHiEE_07230 111 COG0076 GadB, Glutamate decarboxylase and related PLP-dependent proteins Amino acid transport and metabolism 148826631 Common cyaY frataxin-like protein CGSHiEE_08500 12 None None None 148826599 Common - phosphoglyceromutase CGSHiEE_08310 138 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 148826337 Common - predicted ferredoxin CGSHiEE_06860 79 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 148826731 Common - tryptophanyl-tRNA synthetase CGSHiEE_09040 15 COG3691 COG3691, Uncharacterized protein conserved in bacteria Function unknown 148826080 Common - hypothetical protein CGSHiEE_05370 55 COG2912 COG2912, Uncharacterized conserved protein Function unknown 148826509 Common - thiol:disulfide interchange protein DsbA CGSHiEE_07820 64 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 148825366 Common - hypothetical protein CGSHiEE_01250 110 None None None 148826683 Pathogen - hypothetical protein CGSHiEE_08780 1 None None None 148826738 Common rseB periplasmic negative regulator of sigmaE CGSHiEE_09085 20 COG3073 RseA, Negative regulator of sigma E activity Signal transduction mechanisms 148826308 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase CGSHiEE_06685 35 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 148825855 Pathogen - hypothetical protein CGSHiEE_04080 1 None None None 148825383 Common - HNH endonuclease CGSHiEE_01335 3 COG1403 McrA, Restriction endonuclease Defense mechanisms 148825350 Common - 4-hydroxy-3-methylbut-2-en-1-yl diphosphate synthase CGSHiEE_01170 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 148825877 Common - hypothetical protein CGSHiEE_04210 81 COG2166 COG2166, SufE protein probably involved in Fe-S center assembly General function prediction only 148825527 Common - hypothetical protein CGSHiEE_02175 29 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 148826001 Pathogen - hypothetical protein CGSHiEE_04890 1 None None None 148825648 Common - anaerobic ribonucleoside triphosphate reductase CGSHiEE_02930 218 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 148826611 Common ansB L-asparaginase II CGSHiEE_08380 140 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 148825300 Pathogen - hypothetical protein CGSHiEE_00900 1 None None None 148825326 Common - translation-associated GTPase CGSHiEE_01030 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 148825823 Common - DNA polymerase III subunits gamma and tau CGSHiEE_03880 247 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 148826333 Common - hypothetical protein CGSHiEE_06830 36 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 148825147 Common - hypothetical protein CGSHiEE_00095 139 COG0545 FkpA, FKBP-type peptidyl-prolyl cis-trans isomerases 1 Posttranslational modification, protein turnover, chaperones 148825899 Common glgA glycogen synthase CGSHiEE_04330 140 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 148826144 Common - predicted ABC-type cobalt transport system, ATPase component CGSHiEE_05755 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 148826366 Common - 2-isopropylmalate synthase CGSHiEE_07035 216 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 148825642 Common - cystathionine gamma-synthase CGSHiEE_02890 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 148826105 Pathogen - hypothetical protein CGSHiEE_05530 1 None None None 148825511 Common - ATP-dependent helicase HepA CGSHiEE_02060 139 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 148825170 Common - 6-phosphogluconate dehydrogenase CGSHiEE_00210 181 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 148825472 Common uvrA excinuclease ABC subunit A CGSHiEE_01845 3 None None None 148825539 Common - chorismate synthase CGSHiEE_02270 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 148825798 Common kgd alpha-ketoglutarate decarboxylase CGSHiEE_03745 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 148826279 Common - Xylose operon regulatory protein CGSHiEE_06530 92 COG1609 PurR, Transcriptional regulators Transcription 148826497 Common - predicted 5-formyltetrahydrofolate cyclo-ligase CGSHiEE_07750 190 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 148825664 Common uvrC excinuclease ABC subunit C CGSHiEE_03020 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 148826553 Common - DNA-directed RNA polymerase subunit alpha CGSHiEE_08050 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 148826274 Common - xylose isomerase CGSHiEE_06495 69 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 148825359 Common - iron (chelated) ABC transporter permease protein CGSHiEE_01215 187 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 148825550 Common - alcohol dehydrogenase class III CGSHiEE_02335 198 COG1062 AdhC, Zn-dependent alcohol dehydrogenases, class III Energy production and conversion 148825860 Common - putative ATPase CGSHiEE_04125 229 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148826087 Common - Sel1 domain protein repeat-containing protein CGSHiEE_05405 127 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 148826314 Common - hypothetical protein CGSHiEE_06715 23 COG2707 COG2707, Predicted membrane protein Function unknown 148826701 Pathogen - hypothetical protein CGSHiEE_08880 1 None None None 148825815 Common - integration host factor beta-subunit CGSHiEE_03840 206 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 148825482 Common - hypothetical protein CGSHiEE_01905 4 None None None 148825208 Common rplA 50S ribosomal protein L1 CGSHiEE_00420 248 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 148825162 Common - hypothetical protein CGSHiEE_00170 104 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 148826125 Common - predicted repair protein CGSHiEE_05640 10 COG3219 COG3219, Uncharacterized protein conserved in bacteria Function unknown 148825285 Common - competence protein E CGSHiEE_00815 141 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 148825452 Common - RNA polymerase factor sigma-32 CGSHiEE_01710 15 COG4390 COG4390, Uncharacterized protein conserved in bacteria Function unknown 148826166 Common - predicted ATPase CGSHiEE_05875 42 COG3106 COG3106, Predicted ATPase General function prediction only 148826099 Pathogen - hypothetical protein CGSHiEE_05480 1 None None None 148825700 Common - lipoyl synthase CGSHiEE_03215 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 148826747 Common - hypothetical protein CGSHiEE_09130 3 None None None 148826529 Common - intracellular septation protein A CGSHiEE_07930 89 COG2917 COG2917, Intracellular septation protein A Cell division and chromosome partitioning 148825768 Common - SoxR-reducing system protein RsxE CGSHiEE_03595 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 148825711 Common - formate dehydrogenase, iron-sulfur subunit CGSHiEE_03280 160 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 148825211 Common - potassium-tellurite ethidium and proflavin transporter CGSHiEE_00435 46 COG1275 TehA, Tellurite resistance protein and related permeases Inorganic ion transport and metabolism 148825432 Common - probable cation-transporting ATPase CGSHiEE_01610 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 148825936 Common - DNA polymerase III subunit chi CGSHiEE_04555 56 COG2927 HolC, DNA polymerase III, chi subunit DNA replication, recombination, and repair 148826399 Common rpmG 50S ribosomal protein L33 CGSHiEE_07210 137 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 148825565 Common - N-acetyl-D-glucosamine kinase CGSHiEE_02450 144 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148825445 Common rbn ribonuclease BN CGSHiEE_01675 26 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 148826623 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase CGSHiEE_08450 134 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 148826164 Common - modification methylase CGSHiEE_05865 133 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 148825268 Common - hypothetical protein CGSHiEE_00730 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 148825596 Common engA GTP-binding protein EngA CGSHiEE_02605 237 COG1160 COG1160, Predicted GTPases General function prediction only 148825761 Common - putative UDP-galactose--lipooligosaccharide galactosyltransferase CGSHiEE_03560 100 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148826348 Common - thiamin ABC transporter periplasmic-binding protein CGSHiEE_06925 51 COG4143 TbpA, ABC-type thiamine transport system, periplasmic component Coenzyme metabolism 148826240 Common - ABC transporter ATP-binding protein CGSHiEE_06305 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 148826657 Common - hypothetical protein CGSHiEE_08640 23 COG3076 COG3076, Uncharacterized protein conserved in bacteria Function unknown 148826514 Common - nucleoid-associated protein NdpA CGSHiEE_07855 31 COG3081 COG3081, Nucleoid-associated protein General function prediction only 148825389 Common recO DNA repair protein RecO CGSHiEE_01385 127 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 148826132 Common lolB outer membrane lipoprotein LolB CGSHiEE_05685 36 COG3017 LolB, Outer membrane lipoprotein involved in outer membrane biogenesis Cell envelope biogenesis, outer membrane 148826392 Common - cAMP-regulatory protein CGSHiEE_07175 159 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 148825615 Common - hypothetical protein CGSHiEE_02735 27 COG2966 COG2966, Uncharacterized conserved protein Function unknown 148825256 Common - ribose-5-phosphate isomerase A CGSHiEE_00670 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 148826644 Pathogen - hypothetical protein CGSHiEE_08565 1 None None None 148825657 Common - dnaK suppressor protein CGSHiEE_02985 143 COG1734 DksA, DnaK suppressor protein Signal transduction mechanisms 148825917 Common - phosphate regulon transcriptional regulatory protein PhoB CGSHiEE_04450 223 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148825541 Common - O-succinylbenzoic acid--CoA ligase CGSHiEE_02280 199 COG0318 CaiC, Acyl-CoA synthetases (AMP-forming)/AMP-acid ligases II Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148825744 Common - ribosome-associated GTPase CGSHiEE_03465 142 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 148826048 Common nusB transcription antitermination protein NusB CGSHiEE_05155 189 COG0781 NusB, Transcription termination factor Transcription 148825948 Common - putative cro repressor CGSHiEE_04615 7 COG1476 COG1476, Predicted transcriptional regulators Transcription 148825557 Common - Na(+)-translocating NADH-quinone reductase subunit F CGSHiEE_02380 157 COG2871 NqrF, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrF Energy production and conversion 148825312 Common - 23S rRNA pseudouridylate synthase C CGSHiEE_00960 182 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 148826232 Common nrdG anaerobic ribonucleotide reductase-activating protein CGSHiEE_06265 59 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 148825704 Common - GTP-binding protein LepA CGSHiEE_03235 206 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 148826041 Common pheS phenylalanyl-tRNA synthetase subunit alpha CGSHiEE_05120 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 148826531 Common mglC beta-methylgalactoside transporter inner membrane component CGSHiEE_07940 130 COG4211 MglC, ABC-type glucose/galactose transport system, permease component Carbohydrate transport and metabolism 148825910 Common - threonyl-tRNA synthetase CGSHiEE_04405 161 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 148826532 Common - galactose/methyl galaxtoside transporter ATP-binding protein CGSHiEE_07945 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148826510 Common - hypothetical protein CGSHiEE_07825 18 COG3084 COG3084, Uncharacterized protein conserved in bacteria Function unknown 148826222 Common - phosphoserine aminotransferase CGSHiEE_06205 119 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 148826356 Common - hypothetical protein CGSHiEE_06985 12 None None None 148825908 Common - probable molybdenum-pterin binding protein CGSHiEE_04395 68 COG3585 MopI, Molybdopterin-binding protein Coenzyme metabolism 148825156 Common - phosphoglycolate phosphatase CGSHiEE_00140 200 COG0546 Gph, Predicted phosphatases General function prediction only 148825500 Common cyaA adenylate cyclase CGSHiEE_01995 25 COG3072 CyaA, Adenylate cyclase Nucleotide transport and metabolism 148825729 Common prfC peptide chain release factor 3 CGSHiEE_03370 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 148826014 Common - D-alanyl-D-alanine carboxypeptidase/endopeptidase CGSHiEE_04965 9 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 148826569 Common rpsQ 30S ribosomal protein S17 CGSHiEE_08130 237 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 148825966 Common - universal stress protein UspE CGSHiEE_04705 4 None None None 148825153 Common greB transcription elongation factor GreB CGSHiEE_00125 214 COG2183 Tex, Transcriptional accessory protein Transcription 148826547 Common frr ribosome recycling factor CGSHiEE_08020 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 148825547 Common - sec-independent translocase CGSHiEE_02320 23 COG1826 TatA, Sec-independent protein secretion pathway components Intracellular trafficking and secretion 148826533 Common - galactose ABC transporter periplasmic-binding protein CGSHiEE_07950 96 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148826098 Pathogen - hypothetical protein CGSHiEE_05475 1 None None None 148825549 Common - putative HTH-type transcriptional regulator CGSHiEE_02330 68 COG0789 SoxR, Predicted transcriptional regulators Transcription 148826519 Common - lysyl-tRNA synthetase CGSHiEE_07880 230 COG2269 COG2269, Truncated, possibly inactive, lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 148826118 Common - HMW1B, OMP-85-like protein required for secretion of HMW1A and HMW2A CGSHiEE_05605 22 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 148826727 Common rplJ 50S ribosomal protein L10 CGSHiEE_09020 205 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 148825742 Common - oligoribonuclease CGSHiEE_03455 88 COG1949 Orn, Oligoribonuclease (3'->5' exoribonuclease) RNA processing and modification 148826145 Common - aromatic-amino-acid aminotransferase CGSHiEE_05760 12 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 148825998 Common - dsDNA-mimic protein CGSHiEE_04875 6 None None None 148825207 Common rplK 50S ribosomal protein L11 CGSHiEE_00415 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 148825956 Pathogen - hypothetical protein CGSHiEE_04655 3 None None None 148825801 Common - ribonucleotide-diphosphate reductase subunit alpha CGSHiEE_03760 201 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 148826261 Common - transaldolase B CGSHiEE_06420 184 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 148825904 Common - DNA topoisomerase I CGSHiEE_04365 97 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 148825235 Common - F0F1 ATP synthase subunit I CGSHiEE_00555 3 COG3312 AtpI, F0F1-type ATP synthase, subunit I Energy production and conversion 148825461 Common - putative deoxyribonucleotide triphosphate pyrophosphatase CGSHiEE_01765 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 148825542 Common - esterase/lipase CGSHiEE_02295 168 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148826740 Common - hypothetical protein CGSHiEE_09095 37 COG2938 COG2938, Uncharacterized conserved protein Function unknown 148825791 Common - putative solute/DNA competence effector CGSHiEE_03710 26 COG3109 ProQ, Activator of osmoprotectant transporter ProP Signal transduction mechanisms 148826398 Common rpmB 50S ribosomal protein L28 CGSHiEE_07205 154 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 148826409 Common - hypothetical protein CGSHiEE_07260 4 None None None 148826563 Common rplF 50S ribosomal protein L6 CGSHiEE_08100 234 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 148825367 Common adk adenylate kinase CGSHiEE_01255 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 148826469 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase CGSHiEE_07600 31 COG2259 COG2259, Predicted membrane protein Function unknown 148825712 Common - formate dehydrogenase major subunit CGSHiEE_03285 175 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 148825360 Common - transcriptional activator CGSHiEE_01220 75 COG0819 TenA, Putative transcription activator Transcription 148825278 Common - hypothetical protein CGSHiEE_00780 166 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 148826460 Common - predicted membrane-fusion protein CGSHiEE_07545 169 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 148825276 Common - DNA topoisomerase III CGSHiEE_00770 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 148826585 Common - autoinducer-2 (AI-2) modifying protein LsrG CGSHiEE_08230 24 COG1359 COG1359, Uncharacterized conserved protein Function unknown 148825376 Common trmB tRNA (guanine-N(7))-methyltransferase CGSHiEE_01300 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 148825913 Common - hypothetical protein CGSHiEE_04430 24 COG3586 COG3586, Uncharacterized conserved protein Function unknown 148826653 Common - hypothetical protein CGSHiEE_08620 3 None None None 148825327 Common - translation-associated GTPase CGSHiEE_01045 109 COG0349 Rnd, Ribonuclease D Translation, ribosomal structure and biogenesis 148826200 Common - predicted PP-loop superfamily ATPase CGSHiEE_06085 175 COG0603 COG0603, Predicted PP-loop superfamily ATPase General function prediction only 148826185 Common - amidophosphoribosyltransferase CGSHiEE_06000 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 148825984 Common - ClpXP protease specificity-enhancing factor CGSHiEE_04805 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 148826557 Common rpmJ 50S ribosomal protein L36 CGSHiEE_08070 137 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 148826231 Common - cysteine/glutathione ABC transporter membrane/ATP-binding component CGSHiEE_06260 249 COG4987 CydC, ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 148825409 Common ruvB Holliday junction DNA helicase B CGSHiEE_01495 230 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 148825707 Common - DNA polymerase III subunit psi CGSHiEE_03260 15 COG3050 HolD, DNA polymerase III, psi subunit DNA replication, recombination, and repair 148826169 Common - peptide ABC transporter ATP-binding protein CGSHiEE_05900 249 COG4170 SapD, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 148826380 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit CGSHiEE_07105 191 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 148826345 Common - transketolase CGSHiEE_06900 221 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 148825297 Common pssA phosphatidylserine synthase CGSHiEE_00885 97 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 148826207 Common dppF dipeptide transporter ATP-binding subunit CGSHiEE_06130 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 148826252 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase CGSHiEE_06375 220 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 148825892 Common - cytidine deaminase CGSHiEE_04285 166 COG0591 PutP, Na+/proline symporter Amino acid transport and metabolism / General function prediction only 148826670 Common tpiA triosephosphate isomerase CGSHiEE_08705 219 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 148825583 Common - putative protein-S-isoprenylcysteine methyltransferase CGSHiEE_02540 34 COG2020 STE14, Putative protein-S-isoprenylcysteine methyltransferase Posttranslational modification, protein turnover, chaperones 148825611 Pathogen - transposase CGSHiEE_02715 2 None None None 148826139 Common - HicB CGSHiEE_05730 28 COG4226 HicB, Uncharacterized protein encoded in hypervariable junctions of pilus gene clusters Function unknown 148826476 Common rpmA 50S ribosomal protein L27 CGSHiEE_07635 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 148825468 Common - transport protein ExbB CGSHiEE_01800 20 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 148825316 Common - DNA mismatch repair protein CGSHiEE_00980 28 COG3066 MutH, DNA mismatch repair protein DNA replication, recombination, and repair 148825476 Common tgt queuine tRNA-ribosyltransferase CGSHiEE_01865 5 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 148826629 Common - diaminopimelate decarboxylase CGSHiEE_08490 219 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 148825863 Common - transposase CGSHiEE_04140 7 None None None 148826005 Common - hypothetical protein CGSHiEE_04910 6 None None None 148826428 Common - hypothetical protein CGSHiEE_07375 24 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 148825930 Common valS valyl-tRNA synthetase CGSHiEE_04525 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148826414 Common - cytochrome c-type biogenesis protein NrfE CGSHiEE_07285 137 COG1138 CcmF, Cytochrome c biogenesis factor Posttranslational modification, protein turnover, chaperones 148825830 Common - hypothetical protein CGSHiEE_03915 17 COG5339 COG5339, Uncharacterized protein conserved in bacteria Function unknown 148825605 Common - cystathionine beta-lyase CGSHiEE_02675 6 COG5413 COG5413, Uncharacterized integral membrane protein Function unknown 148825538 Common mepA penicillin-insensitive murein endopeptidase CGSHiEE_02265 40 COG3770 MepA, Murein endopeptidase Cell envelope biogenesis, outer membrane 148825696 Common - citrate lyase beta chain CGSHiEE_03195 112 COG2301 CitE, Citrate lyase beta subunit Carbohydrate transport and metabolism 148826355 Common rpmH 50S ribosomal protein L34 CGSHiEE_06980 191 COG0230 RpmH, Ribosomal protein L34 Translation, ribosomal structure and biogenesis 148825851 Common - acetyl-CoA carboxylase subunit beta CGSHiEE_04050 219 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 148826708 Common glpX fructose 1,6-bisphosphatase II CGSHiEE_08915 201 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 148826622 Common - UDP-2,3-diacylglucosamine hydrolase CGSHiEE_08445 82 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 148826305 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase CGSHiEE_06660 219 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 148825146 Common - hypothetical protein CGSHiEE_00090 49 COG2964 COG2964, Uncharacterized protein conserved in bacteria Function unknown 148825497 Common - phosphate-starvation-inducible protein PsiE CGSHiEE_01980 20 COG3223 COG3223, Predicted membrane protein Function unknown 148826453 Common thyA thymidylate synthase CGSHiEE_07500 85 COG0730 COG0730, Predicted permeases General function prediction only 148825324 Common - hypothetical protein CGSHiEE_01020 61 COG2914 COG2914, Uncharacterized protein conserved in bacteria Function unknown 148825423 Common - putative type IV pilin secretion protein CGSHiEE_01565 210 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 148826100 Common - Outer membrane lipoprotein PCP precursor CGSHiEE_05495 17 COG3133 SlyB, Outer membrane lipoprotein Cell envelope biogenesis, outer membrane 148825785 Common moaA molybdenum cofactor biosynthesis protein A CGSHiEE_03680 203 COG2896 MoaA, Molybdenum cofactor biosynthesis enzyme Coenzyme metabolism 148825295 Pathogen - rRNA methylase CGSHiEE_00875 1 None None None 148826668 Common - hypothetical protein CGSHiEE_08695 94 COG2962 RarD, Predicted permeases General function prediction only 148826272 Common rfaD ADP-L-glycero-D-mannoheptose-6-epimerase CGSHiEE_06485 163 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148826687 Common - xanthine-guanine phosphoribosyltransferase CGSHiEE_08800 71 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 148825353 Common - hypothetical protein CGSHiEE_01185 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 148825288 Common nudC NADH pyrophosphatase CGSHiEE_00830 112 COG2816 NPY1, NTP pyrophosphohydrolases containing a Zn-finger, probably nucleic-acid-binding DNA replication, recombination, and repair 148826360 Common - DNA polymerase III subunit beta CGSHiEE_07005 215 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 148825253 Common - hypothetical protein CGSHiEE_00655 137 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 148825689 Common - lipoprotein CGSHiEE_03160 136 COG0797 RlpA, Lipoproteins Cell envelope biogenesis, outer membrane 148825943 Pathogen - hypothetical protein CGSHiEE_04590 1 None None None 148825769 Common - electron transport complex protein RnfG CGSHiEE_03600 58 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 148826752 Common recA recombinase A CGSHiEE_09155 244 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 148825260 Common mazG nucleoside triphosphate pyrophosphohydrolase CGSHiEE_00690 158 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 148825759 Common - putative UDP-glcNAc--lipooligosaccharide N-acetylglucosaminyl glycosyltransferase CGSHiEE_03550 15 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 148826536 Common - galactokinase CGSHiEE_07965 82 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 148826387 Common ileS isoleucyl-tRNA synthetase CGSHiEE_07150 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148825342 Common hscB co-chaperone HscB CGSHiEE_01130 53 COG1076 DjlA, DnaJ-domain-containing proteins 1 Posttranslational modification, protein turnover, chaperones 148826229 Common hemH ferrochelatase CGSHiEE_06250 246 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 148825644 Common cysS cysteinyl-tRNA synthetase CGSHiEE_02910 77 COG1946 TesB, Acyl-CoA thioesterase Lipid metabolism 148825530 Common aroK shikimate kinase CGSHiEE_02205 202 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 148826635 Common - cell developmental protein SirA CGSHiEE_08520 86 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 148825438 Common - 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylic acid synthase/2-oxoglutarate decarboxylase CGSHiEE_01640 79 COG1165 MenD, 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase Coenzyme metabolism 148826447 Common - preprotein translocase subunit SecA CGSHiEE_07470 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 148825160 Common - asparagine synthetase AsnA CGSHiEE_00160 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 148826697 Common - hypothetical protein CGSHiEE_08860 62 COG3550 HipA, Uncharacterized protein related to capsule biosynthesis enzymes General function prediction only 148825905 Pathogen - hypothetical protein CGSHiEE_04370 1 None None None 148826578 Common rplC 50S ribosomal protein L3 CGSHiEE_08185 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 148825560 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase CGSHiEE_02405 181 COG1496 COG1496, Uncharacterized conserved protein Function unknown 148826174 Common - putative L-lactate permease CGSHiEE_05935 103 COG1620 LldP, L-lactate permease Energy production and conversion 148825912 Common - condesin subunit E CGSHiEE_04415 20 COG3095 MukE, Uncharacterized protein involved in chromosome partitioning Cell division and chromosome partitioning 148825677 Common - hypothetical protein CGSHiEE_03085 43 COG3768 COG3768, Predicted membrane protein Function unknown 148825660 Common - lipid transporter ATP-binding/permease protein CGSHiEE_03000 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148826667 Common - DNA-binding transcriptional regulator IlvY CGSHiEE_08690 184 COG0583 LysR, Transcriptional regulator Transcription 148825946 Common - hypothetical protein CGSHiEE_04605 15 COG3645 COG3645, Uncharacterized phage-encoded protein Function unknown 148825617 Common - Signal recognition particle protein CGSHiEE_02745 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 148825169 Common - glucose-6-phosphate 1-dehydrogenase CGSHiEE_00205 3 None None None 148825683 Common - exonuclease III CGSHiEE_03130 249 COG4178 COG4178, ABC-type uncharacterized transport system, permease and ATPase components General function prediction only 148826614 Common - hypothetical protein CGSHiEE_08395 13 None None None 148825626 Common - putative D-alanyl-D-alanine carboxypeptidase CGSHiEE_02790 24 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 148825186 Common ureB urease subunit beta CGSHiEE_00290 96 COG0832 UreB, Urea amidohydrolase (urease) beta subunit Amino acid transport and metabolism 148825499 Common - phosphate-starvation-inducible protein PsiE CGSHiEE_01990 55 COG2959 HemX, Uncharacterized enzyme of heme biosynthesis Coenzyme metabolism 148826283 Common - putative sulfate transport protein CysZ CGSHiEE_06550 44 COG2981 CysZ, Uncharacterized protein involved in cysteine biosynthesis Amino acid transport and metabolism 148826673 Common xerC site-specific tyrosine recombinase XerC CGSHiEE_08720 65 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 148826037 Common - hypothetical protein CGSHiEE_05100 21 COG2378 COG2378, Predicted transcriptional regulator Transcription 148826259 Common - carbon starvation protein, predicted membrane protein CGSHiEE_06410 109 COG1966 CstA, Carbon starvation protein, predicted membrane protein Signal transduction mechanisms 148825486 Common - lipoprotein NlpI CGSHiEE_01925 26 COG4785 NlpI, Lipoprotein NlpI, contains TPR repeats General function prediction only 148826046 Common - phosphatidylglycerophosphatase A CGSHiEE_05145 100 COG1267 PgpA, Phosphatidylglycerophosphatase A and related proteins Lipid metabolism 148826095 Common - pyruvate kinase CGSHiEE_05445 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 148825670 Common - putative TRAP-type C4-dicarboxylate transport system, large permease component CGSHiEE_03050 126 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 148825410 Common ruvB Holliday junction DNA helicase B CGSHiEE_01500 4 None None None 148825928 Common - bifunctional indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase CGSHiEE_04515 220 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 148826032 Common - hypothetical protein CGSHiEE_05075 69 COG3943 COG3943, Virulence protein General function prediction only 148826057 Common - DNA topoisomerase IV subunit A CGSHiEE_05235 126 COG0189 RimK, Glutathione synthase/Ribosomal protein S6 modification enzyme (glutaminyl transferase) Coenzyme metabolism / Translation, ribosomal structure and biogenesis 148825894 Common - glutaminyl-tRNA synthetase CGSHiEE_04295 243 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 148825630 Common - hypothetical protein CGSHiEE_02820 123 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148826357 Pathogen - transferrin-binding protein 2 precursor CGSHiEE_06990 3 None None None 148825652 Common mutL DNA mismatch repair protein CGSHiEE_02960 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 148826300 Common - conserved ABC-type transport system protein, permease component CGSHiEE_06635 151 COG0767 Ttg2B, ABC-type transport system involved in resistance to organic solvents, permease component Secondary metabolites biosynthesis, transport, and catabolism 148825853 Common metX homoserine O-acetyltransferase CGSHiEE_04070 133 COG2021 MET2, Homoserine acetyltransferase Amino acid transport and metabolism 148825567 Common - putative Na+/alanine symporter CGSHiEE_02460 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 148826595 Common mltC murein transglycosylase C CGSHiEE_08290 138 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 148825883 Common - ABC transporter ATPase component CGSHiEE_04240 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 148826711 Common - DNA-3-methyladenine glycosylase CGSHiEE_08930 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 148826328 Common - hypothetical protein CGSHiEE_06805 18 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 148826502 Common - heme-binding lipoprotein CGSHiEE_07775 213 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148826190 Common - N5-glutamine S-adenosyl-L-methionine-dependent methyltransferase CGSHiEE_06035 222 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 148825138 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA CGSHiEE_00050 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 148825749 Common - transcriptional regulatory protein CGSHiEE_03490 222 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148826067 Common - sodium/dicarboxylate symporter protein CGSHiEE_05305 142 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 148825293 Common - fatty acid metabolism regulator CGSHiEE_00865 57 COG2186 FadR, Transcriptional regulators Transcription 148826706 Common - ABC transporter ATP-binding protein CGSHiEE_08905 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 148825832 Common - chaperone protein DnaK CGSHiEE_03925 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 148826506 Common - DNA polymerase I CGSHiEE_07805 50 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 148826103 Common ilvH acetolactate synthase 3 regulatory subunit CGSHiEE_05520 192 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 148826732 Common - tRNA-dihydrouridine synthase A CGSHiEE_09045 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 148825771 Common - electron transport complex protein RnfC CGSHiEE_03610 86 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 148826386 Common - bifunctional riboflavin kinase/FMN adenylyltransferase CGSHiEE_07145 211 COG0196 RibF, FAD synthase Coenzyme metabolism 148825441 Common - uridine phosphorylase CGSHiEE_01655 99 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 148826419 Common - hypothetical protein CGSHiEE_07330 54 COG0754 Gsp, Glutathionylspermidine synthase Amino acid transport and metabolism 148826024 Common rpmI 50S ribosomal protein L35 CGSHiEE_05015 30 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 148825209 Common rpoB DNA-directed RNA polymerase subunit beta CGSHiEE_00425 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 148825248 Common hisH imidazole glycerol phosphate synthase subunit HisH CGSHiEE_00630 217 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 148826016 Pathogen - hypothetical protein CGSHiEE_04975 1 None None None 148825194 Common dnaG DNA primase CGSHiEE_00330 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 148825467 Common bcp thioredoxin-dependent thiol peroxidase CGSHiEE_01795 211 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148825475 Common - hypothetical protein CGSHiEE_01860 18 None None None 148825752 Common - leucyl aminopeptidase CGSHiEE_03505 188 COG0260 PepB, Leucyl aminopeptidase Amino acid transport and metabolism 148826214 Pathogen - hypothetical protein CGSHiEE_06165 3 None None None 148825151 Common - DNA-binding transcriptional repressor FabR CGSHiEE_00115 51 COG1309 AcrR, Transcriptional regulator Transcription 148825178 Pathogen - hypothetical protein CGSHiEE_00250 1 None None None 148825919 Common - phosphate transport system permease protein PstA CGSHiEE_04460 222 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 148826457 Common - multidrug resistance protein A CGSHiEE_07520 145 COG1566 EmrA, Multidrug resistance efflux pump Defense mechanisms 148826157 Common - adenylosuccinate synthetase CGSHiEE_05830 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 148826474 Common - DNA-binding response regulator in two-component regulatory system with ArcB or CpxA CGSHiEE_07625 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 148826481 Common - hypothetical protein CGSHiEE_07660 17 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 148825985 Common rpsI 30S ribosomal protein S9 CGSHiEE_04810 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 148825659 Common mutL DNA mismatch repair protein CGSHiEE_02995 168 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 148826288 Pathogen - hypothetical protein CGSHiEE_06575 2 None None None 148826112 Common lolA outer-membrane lipoprotein carrier protein CGSHiEE_05575 67 COG2834 LolA, Outer membrane lipoprotein-sorting protein Cell envelope biogenesis, outer membrane 148825333 Common - long-chain-fatty-acid--CoA ligase CGSHiEE_01075 146 COG0811 TolQ, Biopolymer transport proteins Intracellular trafficking and secretion 148825839 Common - bicyclomycin/multidrug efflux system CGSHiEE_03970 7 COG3955 COG3955, Exopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 148826183 Common - arginine repressor CGSHiEE_05990 79 COG1438 ArgR, Arginine repressor Transcription 148826263 Common oppB oligopeptide transporter permease CGSHiEE_06430 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148825553 Common - Na(+)-translocating NADH-quinone reductase subunit B CGSHiEE_02360 76 COG1805 NqrB, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrB Energy production and conversion 148826633 Common - Trk system potassium uptake protein TrkH CGSHiEE_08510 120 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 148825778 Common - HMW1B, OMP-85-like protein required for secretion of HMW1A and HMW2A CGSHiEE_03645 22 COG2831 FhaC, Hemolysin activation/secretion protein Intracellular trafficking and secretion 148826197 Common - predicted methyltransferase CGSHiEE_06070 185 COG0583 LysR, Transcriptional regulator Transcription 148825971 Common - tryptophan synthase subunit beta CGSHiEE_04740 224 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 148825525 Common - hypothetical protein CGSHiEE_02165 164 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 148825246 Common - imidazole glycerol phosphate synthase subunit HisF CGSHiEE_00620 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 148826591 Common - conserved hypothetical tRNA/rRNA methyltransferase CGSHiEE_08260 160 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 148826431 Pathogen - hypothetical protein CGSHiEE_07390 1 None None None 148826619 Common - acetohydroxy acid synthase II CGSHiEE_08430 220 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 148826570 Common - 50S ribosomal protein L29 CGSHiEE_08135 86 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 148825397 Common - ribonuclease T CGSHiEE_01435 20 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 148825841 Common - hypothetical protein CGSHiEE_04000 42 COG2215 COG2215, ABC-type uncharacterized transport system, permease component General function prediction only 148826148 Common - putative ABC-type Co2+ transport system, periplasmic component CGSHiEE_05775 9 COG5266 CbiK, ABC-type Co2+ transport system, periplasmic component Inorganic ion transport and metabolism 148826659 Common - hypothetical protein CGSHiEE_08650 122 COG0729 COG0729, Outer membrane protein Cell envelope biogenesis, outer membrane 148825299 Common - putative protease CGSHiEE_00895 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 148825757 Common - putative lipooligosaccharide flippase CGSHiEE_03530 43 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 148825369 Common adk adenylate kinase CGSHiEE_01265 41 COG3043 NapB, Nitrate reductase cytochrome c-type subunit Energy production and conversion 148826290 Common - cytochrome C-type biogenesis protein CGSHiEE_06585 89 COG3088 CcmH, Uncharacterized protein involved in biosynthesis of c-type cytochromes Posttranslational modification, protein turnover, chaperones 148825598 Common - uridine kinase CGSHiEE_02635 85 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 148825915 Common sbcB exonuclease I CGSHiEE_04440 52 COG2925 SbcB, Exonuclease I DNA replication, recombination, and repair 148825982 Common - 1-deoxy-D-xylulose-5-phosphate synthase CGSHiEE_04795 226 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 148825846 Common - hypothetical protein CGSHiEE_04025 20 COG3094 COG3094, Uncharacterized protein conserved in bacteria Function unknown 148826107 Common - acetolactate synthase 3 catalytic subunit CGSHiEE_05540 20 COG2916 Hns, DNA-binding protein H-NS General function prediction only 148826277 Common - putative aspartate aminotransferase CGSHiEE_06520 202 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 148826612 Common ansB L-asparaginase II CGSHiEE_08385 86 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 148825188 Common ureE urease accessory protein UreE CGSHiEE_00300 15 COG2371 UreE, Urease accessory protein UreE Posttranslational modification, protein turnover, chaperones 148825307 Common - 23S rRNA pseudouridylate synthase C CGSHiEE_00935 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 148826650 Common - selenocysteine synthase CGSHiEE_08605 12 None None None 148825139 Common rpsL 30S ribosomal protein S12 CGSHiEE_00055 240 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 148825902 Common pntB pyridine nucleotide transhydrogenase CGSHiEE_04355 163 COG0583 LysR, Transcriptional regulator Transcription 148826238 Common - hypothetical protein CGSHiEE_06295 26 COG3117 COG3117, Uncharacterized protein conserved in bacteria Function unknown 148826467 Common - phosphoribosylamine--glycine ligase CGSHiEE_07590 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 148826389 Common ileS isoleucyl-tRNA synthetase CGSHiEE_07160 4 COG5633 COG5633, Predicted periplasmic lipoprotein General function prediction only 148825732 Common - exoribonuclease II CGSHiEE_03395 115 COG1984 DUR1, Allophanate hydrolase subunit 2 Amino acid transport and metabolism 148826620 Common - dihydroxy-acid dehydratase CGSHiEE_08435 88 COG0733 COG0733, Na+-dependent transporters of the SNF family General function prediction only 148826050 Common asnC asparaginyl-tRNA synthetase CGSHiEE_05165 209 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 148826322 Common - predicted PE--lipooligosaccharide phosphorylethanolamine transferase CGSHiEE_06765 56 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 148826402 Common - predicted nucleic acid-binding protein, contains PIN domain CGSHiEE_07225 58 COG1487 VapC, Predicted nucleic acid-binding protein, contains PIN domain General function prediction only 148826120 Common - hypothetical protein CGSHiEE_05615 8 None None None 148826437 Common - CDP-diglyceride synthetase CGSHiEE_07420 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 148826146 Common - cobalt transport protein CbiM CGSHiEE_05765 23 COG0310 CbiM, ABC-type Co2+ transport system, permease component Inorganic ion transport and metabolism 148826343 Common - nucleotide-binding protein CGSHiEE_06890 107 COG1666 COG1666, Uncharacterized protein conserved in bacteria Function unknown 148825719 Common gmk guanylate kinase CGSHiEE_03320 212 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 148825750 Common - sensor protein QseC CGSHiEE_03495 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148826382 Common - O-succinylbenzoate synthase CGSHiEE_07115 48 COG1441 MenC, O-succinylbenzoate synthase Coenzyme metabolism 148826137 Common - riboflavin synthase subunit alpha CGSHiEE_05720 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 148826559 Common rplO 50S ribosomal protein L15 CGSHiEE_08080 87 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 148826299 Common - conserved ABC-type transport system protein, ATPase component CGSHiEE_06630 249 COG1127 Ttg2A, ABC-type transport system involved in resistance to organic solvents, ATPase component Secondary metabolites biosynthesis, transport, and catabolism 148826242 Common - hypothetical protein CGSHiEE_06315 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 148825929 Common - hydrogenase 2 accessory protein HypG CGSHiEE_04520 41 COG0298 HypC, Hydrogenase maturation factor Posttranslational modification, protein turnover, chaperones 148825545 Common - glutamate dehydrogenase CGSHiEE_02310 166 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 148825318 Common - long-chain fatty acid transport protein CGSHiEE_00990 75 COG2067 FadL, Long-chain fatty acid transport protein Lipid metabolism 148825591 Common nagB glucosamine-6-phosphate deaminase CGSHiEE_02580 81 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 148825811 Common - D-lactate dehydrogenase CGSHiEE_03810 73 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 148825280 Common - penicillin-binding protein 1A CGSHiEE_00790 200 COG5009 MrcA, Membrane carboxypeptidase/penicillin-binding protein Cell envelope biogenesis, outer membrane 148826227 Common hemH ferrochelatase CGSHiEE_06240 155 COG0276 HemH, Protoheme ferro-lyase (ferrochelatase) Coenzyme metabolism 148826627 Common cyaY frataxin-like protein CGSHiEE_08480 41 COG1965 CyaY, Protein implicated in iron transport, frataxin homolog Inorganic ion transport and metabolism 148826565 Common rpsN 30S ribosomal protein S14 CGSHiEE_08110 190 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 148825436 Common - aminotransferase AlaT CGSHiEE_01630 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 148825975 Common - aspartate-semialdehyde dehydrogenase CGSHiEE_04760 174 COG1278 CspC, Cold shock proteins Transcription 148826754 Common - camphor resistance protein CrcB CGSHiEE_09165 19 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 148825829 Common mgsA methylglyoxal synthase CGSHiEE_03910 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 148826160 Common dapD 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase CGSHiEE_05845 128 COG1609 PurR, Transcriptional regulators Transcription 148825578 Common acpP acyl carrier protein CGSHiEE_02515 182 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148825822 Common upp uracil phosphoribosyltransferase CGSHiEE_03875 165 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 148825347 Common hscA chaperone protein HscA CGSHiEE_01155 65 COG2976 COG2976, Uncharacterized protein conserved in bacteria Function unknown 148826130 Common - hypothetical protein CGSHiEE_05675 32 COG3103 COG3103, SH3 domain protein Signal transduction mechanisms 148826742 Common trkA potassium transporter peripheral membrane component CGSHiEE_09105 144 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 148825618 Common - putative type I site-specific restriction-modification system, R subunit CGSHiEE_02750 131 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 148825767 Common modC molybdate transporter ATP-binding subunit CGSHiEE_03590 238 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 148826535 Common - galactose-1-phosphate uridylyltransferase CGSHiEE_07960 80 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 148826396 Common - bifunctional phosphopantothenoylcysteine decarboxylase/phosphopantothenate synthase CGSHiEE_07195 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 148825265 Common - DNA polymerase III subunit delta' CGSHiEE_00715 213 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 148826236 Common nrdG anaerobic ribonucleotide reductase-activating protein CGSHiEE_06285 156 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 148825378 Common - hypothetical protein CGSHiEE_01310 39 COG0628 PerM, Predicted permease General function prediction only 148826545 Common hslO Hsp33-like chaperonin CGSHiEE_08010 137 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 148825330 Common - hypothetical protein CGSHiEE_01060 188 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 148825380 Common mogA molybdenum cofactor biosynthesis protein CGSHiEE_01320 185 COG0521 MoaB, Molybdopterin biosynthesis enzymes Coenzyme metabolism 148825909 Common - predicted dissimilatory sulfite reductase, desulfoviridin, gamma subunit CGSHiEE_04400 60 COG2920 DsrC, Dissimilatory sulfite reductase (desulfoviridin), gamma subunit Inorganic ion transport and metabolism 148825355 Pathogen - hypothetical protein CGSHiEE_01195 1 None None None 148825954 Pathogen - hypothetical protein CGSHiEE_04645 1 None None None 148825238 Common - F0F1 ATP synthase subunit B CGSHiEE_00570 85 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 148826574 Common rpsS 30S ribosomal protein S19 CGSHiEE_08155 246 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 148826566 Common rplE 50S ribosomal protein L5 CGSHiEE_08115 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 148826451 Common thyA thymidylate synthase CGSHiEE_07490 136 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 148825991 Common folE GTP cyclohydrolase I CGSHiEE_04840 196 COG0303 MoeA, Molybdopterin biosynthesis enzyme Coenzyme metabolism 148826319 Common - cytochrome c-type protein NrfB CGSHiEE_06740 16 None None None 148826143 Common - aromatic amino acid aminotransferase CGSHiEE_05750 73 COG1448 TyrB, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 148825858 Common - tellurite resistance protein TehB CGSHiEE_04115 39 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 148826362 Common recF recombination protein F CGSHiEE_07015 30 COG3468 AidA, Type V secretory pathway, adhesin AidA Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148826172 Common - fructose-1,6-bisphosphatase CGSHiEE_05925 108 COG0158 Fbp, Fructose-1,6-bisphosphatase Carbohydrate transport and metabolism 148825639 Common - hypothetical protein CGSHiEE_02875 3 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 148825536 Common - lipid A biosynthesis (KDO)2-(lauroyl)-lipid IVA acyltransferase CGSHiEE_02255 96 COG1560 HtrB, Lauroyl/myristoyl acyltransferase Cell envelope biogenesis, outer membrane 148825645 Common - anaerobic ribonucleoside triphosphate reductase CGSHiEE_02915 100 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 148825666 Common - mannonate dehydratase CGSHiEE_03030 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 148825433 Common - serine transporter CGSHiEE_01615 42 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 148826089 Pathogen - G protein CGSHiEE_05415 1 COG5005 COG5005, Mu-like prophage protein gpG General function prediction only 148825720 Common rpoZ DNA-directed RNA polymerase subunit omega CGSHiEE_03325 108 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 148826350 Common ispH 4-hydroxy-3-methylbut-2-enyl diphosphate reductase CGSHiEE_06935 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 148825818 Common - orotidine 5'-phosphate decarboxylase CGSHiEE_03855 172 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 148825572 Common - hypothetical protein CGSHiEE_02485 43 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 148825937 Common - aspartate-semialdehyde dehydrogenase CGSHiEE_04560 8 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 148825603 Pathogen - hypothetical protein CGSHiEE_02665 1 None None None 148825478 Common secF preprotein translocase subunit SecF CGSHiEE_01885 207 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 148825873 Common truB tRNA pseudouridine synthase B CGSHiEE_04190 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 148826596 Common - hypothetical protein CGSHiEE_08295 72 COG2924 COG2924, Uncharacterized protein conserved in bacteria Function unknown 148825213 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase CGSHiEE_00445 83 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 148825134 Common - hemoglobin-haptoglobin binding protein B CGSHiEE_00010 50 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 148825448 Common pyrE orotate phosphoribosyltransferase CGSHiEE_01690 127 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 148825865 Common - hypothetical protein CGSHiEE_04150 175 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 148825932 Common - hypothetical protein CGSHiEE_04535 16 COG3097 COG3097, Uncharacterized protein conserved in bacteria Function unknown 148826372 Common fis DNA-binding protein Fis CGSHiEE_07065 97 COG2901 Fis, Factor for inversion stimulation Fis, transcriptional activator Transcription / DNA replication, recombination, and repair 148825322 Common xseA exodeoxyribonuclease VII large subunit CGSHiEE_01010 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 148825562 Common - conserved hypothetical lipoprotein CGSHiEE_02415 123 COG4105 ComL, DNA uptake lipoprotein General function prediction only 148825726 Common - predicted branched-chain amino acid permease CGSHiEE_03355 84 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 148826681 Common - Ferrichrome transport ATP-binding protein fhuC CGSHiEE_08770 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 148825421 Pathogen - hypothetical protein CGSHiEE_01555 1 COG4968 PilE, Tfp pilus assembly protein PilE Cell motility and secretion / Intracellular trafficking and secretion 148826440 Common leuS leucyl-tRNA synthetase CGSHiEE_07435 34 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 148826645 Common - hypothetical protein CGSHiEE_08580 32 COG3041 COG3041, Uncharacterized protein conserved in bacteria Function unknown 148826082 Common - 2-dehydro-3-deoxyphosphooctonate aldolase CGSHiEE_05380 3 COG1714 COG1714, Predicted membrane protein/domain Function unknown 148825471 Common - single-strand DNA-binding protein CGSHiEE_01815 213 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 148825795 Common - conserved putative deoxyribonuclease CGSHiEE_03730 90 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 148825551 Common - esterase CGSHiEE_02340 99 COG0627 COG0627, Predicted esterase General function prediction only 148826630 Common - nitrate/nitrite response regulator protein CGSHiEE_08495 219 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 148825803 Common - hypothetical protein CGSHiEE_03770 114 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 148825787 Common moaD molybdopterin synthase small subunit CGSHiEE_03690 63 COG1977 MoaD, Molybdopterin converting factor, small subunit Coenzyme metabolism 148826270 Common - deoxyribose-phosphate aldolase CGSHiEE_06475 63 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 148826688 Pathogen - hypothetical protein CGSHiEE_08805 1 None None None 148825411 Common xerD site-specific tyrosine recombinase XerD CGSHiEE_01505 225 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148825671 Common - mannonate dehydratase CGSHiEE_03055 148 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148825896 Common - hypothetical protein CGSHiEE_04305 119 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 148825585 Common - hypothetical protein CGSHiEE_02550 123 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 148826586 Common - ribulose-phosphate 3-epimerase CGSHiEE_08235 215 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 148826327 Common - putative type III restriction/modification system modification methylase CGSHiEE_06790 122 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 148825837 Common - bicyclomycin resistance protein CGSHiEE_03960 55 None None None 148825251 Common hisD histidinol dehydrogenase CGSHiEE_00645 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 148825926 Common - anthranilate synthase component II CGSHiEE_04495 232 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 148825774 Common - predicted inner membrane peptidase CGSHiEE_03625 189 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148825632 Common - hypothetical protein CGSHiEE_02830 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 148825173 Common apaH diadenosine tetraphosphatase CGSHiEE_00225 16 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 148825569 Common pflA pyruvate formate lyase-activating enzyme 1 CGSHiEE_02470 19 COG3056 COG3056, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 148825765 Common modC molybdate transporter ATP-binding protein CGSHiEE_03580 249 COG4148 ModC, ABC-type molybdate transport system, ATPase component Inorganic ion transport and metabolism 148826338 Common - UDP-N-acetylglucosamine acyltransferase CGSHiEE_06865 2 None None None 148825456 Common - dihydroneopterin aldolase CGSHiEE_01730 108 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 148826351 Common lspA lipoprotein signal peptidase CGSHiEE_06960 166 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 148826704 Common - hypothetical protein CGSHiEE_08895 27 COG4679 COG4679, Phage-related protein Function unknown 148826202 Common - predicted organic radical activating enzyme CGSHiEE_06095 173 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 148825505 Common - FolD bifunctional protein CGSHiEE_02020 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 148826030 Common - NAD-dependent deacetylase sirtuin 5 CGSHiEE_05065 138 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 148825372 Common - periplasmic nitrate reductase CGSHiEE_01280 187 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 148826075 Common - 8-amino-7-oxononanoate synthase CGSHiEE_05345 189 COG0156 BioF, 7-keto-8-aminopelargonate synthetase and related enzymes Coenzyme metabolism 148825408 Common ruvA Holliday junction DNA helicase motor protein CGSHiEE_01490 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 148826699 Common - hypothetical ABC transporter, ATP-binding protein CGSHiEE_08870 248 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 148826576 Common rplW 50S ribosomal protein L23 CGSHiEE_08165 82 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 148826665 Common - ketol-acid reductoisomerase CGSHiEE_08680 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 148826734 Common - predicted chloride channel protein CGSHiEE_09055 6 None None None 148826408 Common - exodeoxyribonuclease V gamma chain CGSHiEE_07255 69 COG1330 RecC, Exonuclease V gamma subunit DNA replication, recombination, and repair 148825344 Common hscA chaperone protein HscA CGSHiEE_01140 234 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 148826445 Common rpsB 30S ribosomal protein S2 CGSHiEE_07460 190 COG0475 KefB, Kef-type K+ transport systems, membrane components Inorganic ion transport and metabolism 148825776 Common - predicted membrane protein CGSHiEE_03635 48 COG1289 COG1289, Predicted membrane protein Function unknown 148826209 Common gmhA phosphoheptose isomerase CGSHiEE_06140 128 COG0279 GmhA, Phosphoheptose isomerase Carbohydrate transport and metabolism 148825628 Common - iron-utilization periplasmic protein hFbpA CGSHiEE_02810 126 COG1840 AfuA, ABC-type Fe3+ transport system, periplasmic component Inorganic ion transport and metabolism 148826281 Common - transporter protein CGSHiEE_06540 161 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148826035 Common - NAD-dependent deacetylase CGSHiEE_05090 148 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 148826720 Common coaD phosphopantetheine adenylyltransferase CGSHiEE_08975 116 COG1285 SapB, Uncharacterized membrane protein Function unknown 148825167 Common - 6-phosphogluconolactonase CGSHiEE_00195 145 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 148825871 Common infB translation initiation factor IF-2 CGSHiEE_04180 160 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 148826297 Common - heme exporter ATP-binding protein A CGSHiEE_06620 249 COG4133 CcmA, ABC-type transport system involved in cytochrome c biogenesis, ATPase component Posttranslational modification, protein turnover, chaperones 148826690 Common ispD 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase CGSHiEE_08815 196 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 148825363 Common - putative ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component CGSHiEE_01235 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 148825223 Common - probable oxidoreductase OrdL CGSHiEE_00495 117 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 148825620 Common - predicted transcriptional regulator containing an HTH domain CGSHiEE_02760 67 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 148825523 Common - hypothetical protein CGSHiEE_02155 125 COG0339 Dcp, Zn-dependent oligopeptidases Amino acid transport and metabolism 148826538 Common - hypothetical protein CGSHiEE_07975 26 COG3079 COG3079, Uncharacterized protein conserved in bacteria Function unknown 148826718 Common - putative NADPH-quinone reductase, modulator of drug activity B CGSHiEE_08965 46 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 148826483 Common - undecaprenyl-phosphate galactosephosphotransferase CGSHiEE_07670 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 148826455 Common - gamma-glutamyl kinase CGSHiEE_07510 190 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 148826528 Common - Trp operon repressor CGSHiEE_07925 117 COG1607 COG1607, Acyl-CoA hydrolase Lipid metabolism 148826179 Common - thiol-disulfide interchange protein CGSHiEE_05970 59 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 148825465 Common - putative deoxyribonucleotide triphosphate pyrophosphatase CGSHiEE_01785 12 COG3317 NlpB, Uncharacterized lipoprotein Cell envelope biogenesis, outer membrane 148825681 Common - rod shape-determining protein MreD CGSHiEE_03105 35 COG2891 MreD, Cell shape-determining protein Cell envelope biogenesis, outer membrane 148825199 Common - putative ferredoxin-like protein CGSHiEE_00355 105 COG4231 COG4231, Indolepyruvate ferredoxin oxidoreductase, alpha and beta subunits Energy production and conversion 148825730 Common prfC peptide chain release factor 3 CGSHiEE_03375 232 COG0623 FabI, Enoyl- acyl-carrier-protein 148826114 Common - leucine-responsive transcriptional regulator CGSHiEE_05585 148 COG1522 Lrp, Transcriptional regulators Transcription 148826609 Common - glycerol-3-phosphate acyltransferase CGSHiEE_08370 193 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 148826463 Common - zinc-binding protein CGSHiEE_07570 60 COG3024 COG3024, Uncharacterized protein conserved in bacteria Function unknown 148826265 Common oppD oligopeptide transporter ATP-binding component CGSHiEE_06440 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148826647 Common - hypothetical protein CGSHiEE_08590 25 COG4238 COG4238, Murein lipoprotein Cell envelope biogenesis, outer membrane 148826007 Common - predicted phosphomannomutase CGSHiEE_04920 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 148825808 Common - probable lipoprotein NlpC CGSHiEE_03795 141 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 148825576 Common - 3-oxoacyl-(acyl carrier protein) synthase III CGSHiEE_02505 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 148825244 Common - tyrosine-specific transport protein 1 CGSHiEE_00600 33 COG0814 SdaC, Amino acid permeases Amino acid transport and metabolism 148825399 Pathogen - hypothetical protein CGSHiEE_01445 1 None None None 148825747 Common - hypothetical protein CGSHiEE_03480 4 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 148826376 Common prmA ribosomal protein L11 methyltransferase CGSHiEE_07085 144 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 148825740 Common glnD PII uridylyl-transferase CGSHiEE_03445 123 COG2844 GlnD, UTP:GlnB (protein PII) uridylyltransferase Posttranslational modification, protein turnover, chaperones 148825305 Pathogen - outer membrane opacity protein B CGSHiEE_00925 2 None None None 148825393 Common - lactoylglutathione lyase CGSHiEE_01415 128 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 148825848 Common - hypothetical protein CGSHiEE_04035 2 None None None 148826029 Common - hypothetical protein CGSHiEE_05060 57 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 148826150 Common - hypothetical protein CGSHiEE_05785 89 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 148825722 Common rpoZ DNA-directed RNA polymerase subunit omega CGSHiEE_03335 216 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 148826069 Common - phospho-2-dehydro-3-heoxyheptonate aldolase CGSHiEE_05315 107 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 148826022 Common - hypothetical protein CGSHiEE_05005 218 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 148826729 Common - hypothetical protein CGSHiEE_09030 41 COG2915 COG2915, Uncharacterized protein involved in purine metabolism General function prediction only 148825443 Common - hypothetical protein CGSHiEE_01665 87 COG3012 COG3012, Uncharacterized protein conserved in bacteria Function unknown 148826109 Common - 3-phosphoshikimate 1-carboxyvinyltransferase CGSHiEE_05550 228 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 148826640 Common secE preprotein translocase subunit SecE CGSHiEE_08545 62 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 148825885 Common potC spermidine/putrescine ABC transporter membrane protein CGSHiEE_04250 181 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 148825311 Common - ABC transporter ATP-binding protein CGSHiEE_00955 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 148826472 Common - predicted Na+/alanine symporter CGSHiEE_07615 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 148825196 Common - O-sialoglycoprotein endopeptidase CGSHiEE_00340 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 148825203 Common - hypothetical protein CGSHiEE_00395 14 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 148826216 Common - hypothetical protein CGSHiEE_06175 24 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 148825978 Common - tRNA pseudouridine synthase C CGSHiEE_04775 31 COG3098 COG3098, Uncharacterized protein conserved in bacteria Function unknown 148825518 Common - D,D-heptose 1,7-bisphosphate phosphatase CGSHiEE_02095 132 COG0241 HisB, Histidinol phosphatase and related phosphatases Amino acid transport and metabolism 148825371 Common napG quinol dehydrogenase periplasmic component CGSHiEE_01275 57 COG1145 NapF, Ferredoxin Energy production and conversion 148826600 Common - hypothetical protein CGSHiEE_08325 62 COG2861 COG2861, Uncharacterized protein conserved in bacteria Function unknown 148826159 Pathogen - hypothetical protein CGSHiEE_05840 1 None None None 148826675 Common glpK glycerol kinase CGSHiEE_08730 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 148825271 Common - DNA polymerase III subunit delta' CGSHiEE_00745 4 None None None 148825814 Common cmk cytidylate kinase CGSHiEE_03825 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 148825176 Common ksgA dimethyladenosine transferase CGSHiEE_00240 24 COG3306 COG3306, Glycosyltransferase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 148825868 Common - putative type I restriction enzyme HindVIIP R protein CGSHiEE_04165 136 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 148825206 Common deoD purine nucleoside phosphorylase CGSHiEE_00410 85 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 148825163 Common - predicted membrane protein CGSHiEE_00175 42 COG1297 COG1297, Predicted membrane protein Function unknown 148826598 Common rpmE 50S ribosomal protein L31 CGSHiEE_08305 201 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 148826049 Common ribH riboflavin synthase subunit beta CGSHiEE_05160 229 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 148826603 Common - phosphoribosylformylglycinamidine synthase CGSHiEE_08340 232 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 148825717 Common - long chain fatty acid CoA ligase CGSHiEE_03310 215 COG1022 FAA1, Long-chain acyl-CoA synthetases (AMP-forming) Lipid metabolism 148825428 Common - transcriptional regulator MerR family protein CGSHiEE_01590 142 COG0789 SoxR, Predicted transcriptional regulators Transcription 148826070 Common - outer membrane-specific lipoprotein transporter subunit LolE CGSHiEE_05320 155 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 148826410 Common - hypothetical protein CGSHiEE_07265 4 None None None 148825898 Common glgC glucose-1-phosphate adenylyltransferase CGSHiEE_04325 162 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 148826330 Common - ABC transporter ATP-binding protein CGSHiEE_06815 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148826009 Common - ribosomal RNA large subunit methyltransferase J CGSHiEE_04940 138 COG0293 FtsJ, 23S rRNA methylase Translation, ribosomal structure and biogenesis 148825481 Common - hypothetical protein CGSHiEE_01900 19 COG3036 COG3036, Uncharacterized protein conserved in bacteria Function unknown 148825473 Common queA S-adenosylmethionine:tRNA ribosyltransferase-isomerase CGSHiEE_01850 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 148826496 Common - ClpB CGSHiEE_07745 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 148825826 Common - dihydrolipoamide dehydrogenase CGSHiEE_03895 240 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 148825215 Common - hypothetical protein CGSHiEE_00455 55 COG2862 COG2862, Predicted membrane protein Function unknown 148825797 Common kgd alpha-ketoglutarate decarboxylase CGSHiEE_03740 149 COG0567 SucA, 2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, and related enzymes Energy production and conversion 148825142 Common - elongation factor Tu CGSHiEE_00070 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 148826203 Common - branched-chain amino acid aminotransferase CGSHiEE_06100 52 COG0327 COG0327, Uncharacterized conserved protein Function unknown 148825661 Common lpxK tetraacyldisaccharide 4'-kinase CGSHiEE_03005 130 COG1663 LpxK, Tetraacyldisaccharide-1-P 4'-kinase Cell envelope biogenesis, outer membrane 148825161 Common - DNA-binding transcriptional regulator AsnC CGSHiEE_00165 163 COG1522 Lrp, Transcriptional regulators Transcription 148825789 Common - paraquat-inducible protein B-like protein CGSHiEE_03700 56 COG3008 PqiB, Paraquat-inducible protein B General function prediction only 148826680 Common glpC sn-glycerol-3-phosphate dehydrogenase subunit C CGSHiEE_08765 180 COG0247 GlpC, Fe-S oxidoreductase Energy production and conversion 148826449 Common - hypothetical protein CGSHiEE_07480 4 COG4701 COG4701, Uncharacterized protein conserved in bacteria Function unknown 148825640 Common - hypothetical protein CGSHiEE_02880 3 None None None 148825647 Common - hypothetical protein CGSHiEE_02925 15 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 148825888 Common - peptidase T CGSHiEE_04265 61 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 148825989 Common bioD dithiobiotin synthetase CGSHiEE_04830 23 COG3100 COG3100, Uncharacterized protein conserved in bacteria Function unknown 148825856 Pathogen - hypothetical protein CGSHiEE_04095 2 None None None 148826543 Common - carbon storage regulator CGSHiEE_08000 229 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 148825641 Common - putative deoxyribonuclease CGSHiEE_02885 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 148826639 Common nusG transcription antitermination protein NusG CGSHiEE_08540 215 COG0250 NusG, Transcription antiterminator Transcription 148825382 Common - GTP pyrophosphokinase CGSHiEE_01330 205 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148826000 Pathogen - hypothetical protein CGSHiEE_04885 2 None None None 148825633 Common - succinyl-diaminopimelate desuccinylase CGSHiEE_02835 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 148825491 Common - Na(+)/H(+) antiporter 1 CGSHiEE_01950 106 COG3004 NhaA, Na+/H+ antiporter Inorganic ion transport and metabolism 148825259 Common - coproporphyrinogen III oxidase CGSHiEE_00685 20 COG2990 VirK, Uncharacterized protein conserved in bacteria Function unknown 148826309 Common - CTP synthetase CGSHiEE_06690 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 148825381 Common - diacylglycerol kinase CGSHiEE_01325 109 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 148826176 Common - hypothetical protein CGSHiEE_05955 40 COG1651 DsbG, Protein-disulfide isomerase Posttranslational modification, protein turnover, chaperones 148825920 Common - phosphate transport system permease protein PstC CGSHiEE_04465 228 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 148826244 Common lpxC UDP-3-O-[3-hydroxymyristoyl] N-acetylglucosamine deacetylase CGSHiEE_06325 139 COG0774 LpxC, UDP-3-O-acyl-N-acetylglucosamine deacetylase Cell envelope biogenesis, outer membrane 148826615 Pathogen - hypothetical protein CGSHiEE_08400 1 None None None 148826632 Common - hypothetical protein CGSHiEE_08505 12 COG3078 COG3078, Uncharacterized protein conserved in bacteria Function unknown 148825737 Common - hypothetical protein CGSHiEE_03430 14 COG3112 COG3112, Uncharacterized protein conserved in bacteria Function unknown 148826317 Common - ATP-dependent RNA helicase HrpA CGSHiEE_06730 8 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 148825252 Common hisG ATP phosphoribosyltransferase CGSHiEE_00650 211 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 148825564 Common - probable formate transporter CGSHiEE_02445 100 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 148826342 Common - magnesium/nickel/cobalt transporter CorA CGSHiEE_06885 157 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 148825918 Common - phosphate import ATP-binding protein PstB CGSHiEE_04455 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 148825588 Common - N-acetylmannosamine kinase CGSHiEE_02565 151 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148826140 Common - HicA CGSHiEE_05735 8 None None None 148825703 Common - GTP-binding protein LepA CGSHiEE_03230 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 148826515 Common - small protein A CGSHiEE_07860 62 COG2913 SmpA, Small protein A (tmRNA-binding) Translation, ribosomal structure and biogenesis 148825522 Common - hypothetical protein CGSHiEE_02150 159 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 148826349 Common thiP thiamin transporter membrane protein CGSHiEE_06930 100 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 148826568 Common rplN 50S ribosomal protein L14 CGSHiEE_08125 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 148826084 Common - hypothetical protein CGSHiEE_05390 25 COG0790 COG0790, FOG: TPR repeat, SEL1 subfamily General function prediction only 148825388 Common - opacity associated protein CGSHiEE_01380 12 COG3061 OapA, Cell envelope opacity-associated protein A Cell envelope biogenesis, outer membrane 148826104 Common - acetolactate synthase 3 catalytic subunit CGSHiEE_05525 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 148825833 Common proA gamma-glutamyl phosphate reductase CGSHiEE_03940 188 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 148825546 Common - Sec-independent protein translocase protein TatC CGSHiEE_02315 205 COG0805 TatC, Sec-independent protein secretion pathway component TatC Intracellular trafficking and secretion 148826400 Common - diaminobutyrate--2-oxoglutarate aminotransferase CGSHiEE_07215 237 COG0160 GabT, 4-aminobutyrate aminotransferase and related aminotransferases Amino acid transport and metabolism 148826552 Common rplQ 50S ribosomal protein L17 CGSHiEE_08045 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 148825947 Pathogen - hypothetical protein CGSHiEE_04610 1 None None None 148825656 Common - probable poly polymerase CGSHiEE_02980 213 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 148825951 Pathogen - hypothetical protein CGSHiEE_04630 1 None None None 148826275 Common xylF D-xylose transporter subunit XylF CGSHiEE_06500 103 COG4213 XylF, ABC-type xylose transport system, periplasmic component Carbohydrate transport and metabolism 148826561 Common rpsE 30S ribosomal protein S5 CGSHiEE_08090 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 148825682 Common - rod shape-determining protein MreB CGSHiEE_03125 234 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 148826421 Common glyQ glycyl-tRNA synthetase subunit alpha CGSHiEE_07340 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 148826511 Common mobA molybdopterin-guanine dinucleotide biosynthesis protein A CGSHiEE_07830 87 COG0746 MobA, Molybdopterin-guanine dinucleotide biosynthesis protein A Coenzyme metabolism 148825210 Common - DNA-directed RNA polymerase subunit beta' CGSHiEE_00430 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 148826334 Common - anaerobic dimethyl sulfoxide reductase chain A CGSHiEE_06835 184 COG0243 BisC, Anaerobic dehydrogenases, typically selenocysteine-containing Energy production and conversion 148825994 Common - hypothetical protein CGSHiEE_04855 72 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 148825907 Common - probable zinc protease CGSHiEE_04380 197 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 148826235 Common - hypoxanthine-guanine phosphoribosyltransferase CGSHiEE_06280 149 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 148825575 Common - 3-oxoacyl-(acyl carrier protein) synthase III CGSHiEE_02500 225 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 148826626 Common - prolyl-tRNA synthetase CGSHiEE_08475 209 COG0514 RecQ, Superfamily II DNA helicase DNA replication, recombination, and repair 148826247 Common ddl D-alanine--D-alanine ligase CGSHiEE_06350 215 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 148825269 Common - hypothetical protein CGSHiEE_00735 2 None None None 148826354 Common rnpA ribonuclease P CGSHiEE_06975 190 COG0759 COG0759, Uncharacterized conserved protein Function unknown 148826744 Common fmt methionyl-tRNA formyltransferase CGSHiEE_09115 218 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 148825693 Common - lipoyl synthase CGSHiEE_03180 190 COG0320 LipA, Lipoate synthase Coenzyme metabolism 148825988 Common bioD dithiobiotin synthetase CGSHiEE_04825 125 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 148825414 Common rdgC recombination associated protein CGSHiEE_01520 53 COG2974 RdgC, DNA recombination-dependent growth factor C DNA replication, recombination, and repair 148825728 Common lldD L-lactate dehydrogenase CGSHiEE_03365 6 None None None 148826405 Common - protease DegS CGSHiEE_07240 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 148826658 Common - FKBP-type peptidyl-prolyl cis-trans isomerase SlyD CGSHiEE_08645 129 COG1047 SlpA, FKBP-type peptidyl-prolyl cis-trans isomerases 2 Posttranslational modification, protein turnover, chaperones 148825184 Common groES co-chaperonin GroES CGSHiEE_00280 213 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 148825431 Common - mercuric ion scavenger protein CGSHiEE_01605 50 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 148825459 Common - heme-hemopexin utilization protein C CGSHiEE_01745 88 COG1629 CirA, Outer membrane receptor proteins, mostly Fe transport Inorganic ion transport and metabolism 148826092 Common - hypothetical protein CGSHiEE_05430 9 COG4383 COG4383, Mu-like prophage protein gp29 Function unknown 148825405 Common ntpA dATP pyrophosphohydrolase CGSHiEE_01475 28 None None None 148825593 Common nagA N-acetylglucosamine-6-phosphate deacetylase CGSHiEE_02590 6 COG3203 OmpC, Outer membrane protein (porin) Cell envelope biogenesis, outer membrane 148825900 Common glgA glycogen synthase CGSHiEE_04335 144 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 148826052 Pathogen - hypothetical protein CGSHiEE_05190 2 None None None 148826122 Common - hypothetical protein CGSHiEE_05625 3 None None None 148826464 Common coaE dephospho-CoA kinase CGSHiEE_07575 205 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 148826320 Common - NrfC, Fe-S-cluster-containing hydrogenase component 1 CGSHiEE_06745 165 COG0437 HybA, Fe-S-cluster-containing hydrogenase components 1 Energy production and conversion 148825960 Pathogen - hypothetical protein CGSHiEE_04675 1 None None None 148826163 Pathogen - transposase CGSHiEE_05860 2 None None None 148825446 Common gltX glutamyl-tRNA synthetase CGSHiEE_01680 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 148825157 Common - transposase CGSHiEE_00145 14 COG2963 COG2963, Transposase and inactivated derivatives DNA replication, recombination, and repair 148825958 Pathogen - hypothetical protein CGSHiEE_04665 1 None None None 148826117 Common - HMW2A, high molecular weight adhesin 2 CGSHiEE_05600 165 COG5301 COG5301, Phage-related tail fibre protein General function prediction only 148825470 Common bcp thioredoxin-dependent thiol peroxidase CGSHiEE_01810 22 COG0810 TonB, Periplasmic protein TonB, links inner and outer membranes Cell envelope biogenesis, outer membrane 148826491 Common - aminopeptidase B CGSHiEE_07720 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 148826152 Common - hypothetical protein CGSHiEE_05805 26 COG3105 COG3105, Uncharacterized protein conserved in bacteria Function unknown 148826581 Common - hypothetical protein CGSHiEE_08210 152 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148825516 Common - ATP-dependent helicase HepA CGSHiEE_02085 145 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 148825939 Common fumC fumarate hydratase CGSHiEE_04570 217 COG0114 FumC, Fumarase Energy production and conversion 148826415 Common - thiol-disulfide interchange protein CGSHiEE_07290 119 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 148825242 Common - F0F1 ATP synthase subunit beta CGSHiEE_00590 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 148825191 Common groES co-chaperonin GroES CGSHiEE_00315 34 COG0829 UreH, Urease accessory protein UreH Posttranslational modification, protein turnover, chaperones 148825374 Common napG quinol dehydrogenase periplasmic component CGSHiEE_01290 73 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 148826267 Common - GTPase EngB CGSHiEE_06460 179 COG0218 COG0218, Predicted GTPase General function prediction only 148826028 Common - hypothetical protein CGSHiEE_05055 2 None None None 148826486 Pathogen - hypothetical protein CGSHiEE_07685 1 None None None 148826325 Common lpxB lipid-A-disaccharide synthase CGSHiEE_06780 139 COG0763 LpxB, Lipid A disaccharide synthetase Cell envelope biogenesis, outer membrane 148825812 Common - D-lactate dehydrogenase CGSHiEE_03815 85 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 148825533 Common rimM 16S rRNA-processing protein CGSHiEE_02230 137 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 148825819 Common - translation initiation factor Sui1 CGSHiEE_03860 53 COG0023 SUI1, Translation initiation factor 1 (eIF-1/SUI1) and related proteins Translation, ribosomal structure and biogenesis 148825220 Common - D-ribose transporter ATP binding protein CGSHiEE_00480 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148826211 Common artP arginine transporter ATP-binding subunit CGSHiEE_06150 152 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 148825634 Common thrA bifunctional aspartokinase I/homeserine dehydrogenase I CGSHiEE_02840 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 148825961 Common - integrase/recombinase CGSHiEE_04680 45 COG0582 XerC, Integrase DNA replication, recombination, and repair 148826218 Common - para-aminobenzoate synthase component II CGSHiEE_06185 234 COG0512 PabA, Anthranilate/para-aminobenzoate synthases component II Amino acid transport and metabolism / Coenzyme metabolism 148826371 Common smpB SsrA-binding protein CGSHiEE_07060 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 148826044 Common - dihydrodipicolinate reductase CGSHiEE_05135 215 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 148826340 Common - hypothetical protein CGSHiEE_06875 75 COG0121 COG0121, Predicted glutamine amidotransferase General function prediction only 148825306 Common - hydroxyethylthiazole kinase CGSHiEE_00930 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 148826311 Common - probable cytochrome oxidase subunit I CGSHiEE_06700 166 COG1271 CydA, Cytochrome bd-type quinol oxidase, subunit 1 Energy production and conversion 148826628 Common - hypothetical protein CGSHiEE_08485 2 COG5567 COG5567, Predicted small periplasmic lipoprotein Cell motility and secretion 148825733 Common - hypothetical protein CGSHiEE_03400 100 COG1540 COG1540, Uncharacterized proteins, homologs of lactam utilization protein B General function prediction only 148825404 Common aspS aspartyl-tRNA synthetase CGSHiEE_01470 28 COG1914 MntH, Mn2+ and Fe2+ transporters of the NRAMP family Inorganic ion transport and metabolism 148825974 Common - hypothetical protein CGSHiEE_04755 125 COG2606 EbsC, Uncharacterized conserved protein Function unknown 148826637 Common - putative translation initiation inhibitor, YjgF family protein CGSHiEE_08530 184 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 148826347 Common thiP thiamin transporter membrane protein CGSHiEE_06920 100 COG1178 ThiP, ABC-type Fe3+ transport system, permease component Inorganic ion transport and metabolism 148826186 Common - hypothetical protein CGSHiEE_06015 22 COG3092 COG3092, Uncharacterized protein conserved in bacteria Function unknown 148826588 Common - cell division ATP-binding protein CGSHiEE_08245 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 148826477 Common rpmA 50S ribosomal protein L27 CGSHiEE_07640 33 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 148825415 Common - Holliday junction resolvase-like protein CGSHiEE_01525 149 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 148826676 Common glpQ glycerophosphodiester phosphodiesterase CGSHiEE_08745 105 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 148825835 Common proA gamma-glutamyl phosphate reductase CGSHiEE_03950 6 None None None 148825772 Common - electron transport complex protein RnfB CGSHiEE_03615 111 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 148826604 Common - hypothetical protein CGSHiEE_08345 9 COG3477 COG3477, Predicted periplasmic/secreted protein Function unknown 148826011 Common greA transcription elongation factor GreA CGSHiEE_04950 204 COG0782 GreA, Transcription elongation factor Transcription 148825845 Common - putative ABC transporter ATP-binding protein CGSHiEE_04020 244 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 148825171 Common - 6-phosphogluconate dehydrogenase CGSHiEE_00215 6 None None None 148826367 Common - 2-isopropylmalate synthase CGSHiEE_07040 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 148825339 Common tolB translocation protein TolB precursor CGSHiEE_01115 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 148825453 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase CGSHiEE_01715 200 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 148825264 Common tdk thymidylate kinase CGSHiEE_00710 225 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 148826225 Common - hypothetical protein CGSHiEE_06230 202 COG0277 GlcD, FAD/FMN-containing dehydrogenases Energy production and conversion 148825249 Common - imidazole glycerol-phosphate dehydratase/histidinol phosphatase CGSHiEE_00635 217 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 148825685 Common - hypothetical protein CGSHiEE_03140 200 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 148825941 Common fumC fumarate hydratase CGSHiEE_04580 135 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 148826063 Common - lic-1 operon protein CGSHiEE_05265 52 COG4750 LicC, CTP:phosphocholine cytidylyltransferase involved in choline phosphorylation for cell surface LPS epitopes Cell envelope biogenesis, outer membrane 148826724 Common - aspartate-semialdehyde dehydrogenase CGSHiEE_09005 4 None None None 148825622 Common - seryl-tRNA synthetase CGSHiEE_02770 127 COG0327 COG0327, Uncharacterized conserved protein Function unknown 148825231 Common - hypothetical protein CGSHiEE_00535 74 COG1238 COG1238, Predicted membrane protein Function unknown 148826194 Common - succinyl-CoA synthetase alpha subunit CGSHiEE_06055 217 COG0074 SucD, Succinyl-CoA synthetase, alpha subunit Energy production and conversion 148825462 Common - UDP-galactose--lipooligosaccharide galactosyltransferase CGSHiEE_01770 34 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 148826077 Common - adenosylmethionine--8-amino-7-oxononanoate transaminase CGSHiEE_05355 149 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 148825182 Common rplI 50S ribosomal protein L9 CGSHiEE_00270 209 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 148825225 Common - predicted cytoplasmic sugar-binding protein CGSHiEE_00505 144 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 148825250 Common - histidinol-phosphate aminotransferase CGSHiEE_00640 234 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 148825924 Common - hypothetical protein CGSHiEE_04485 2 None None None 148825200 Common - thymidine kinase CGSHiEE_00360 36 COG3719 Rna, Ribonuclease I Translation, ribosomal structure and biogenesis 148826303 Common - predicted NTP binding protein, contains STAS domain CGSHiEE_06650 6 COG3113 COG3113, Predicted NTP binding protein (contains STAS domain) General function prediction only 148825348 Common hisS histidyl-tRNA synthetase CGSHiEE_01160 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148825613 Common - seryl-tRNA synthetase CGSHiEE_02725 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 148825494 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein CGSHiEE_01965 238 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 148825429 Common - mercuric ion scavenger protein CGSHiEE_01595 50 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 148826722 Common - lysophospholipase L2 CGSHiEE_08985 61 COG2267 PldB, Lysophospholipase Lipid metabolism 148825606 Common znuA high-affinity zinc transporter periplasmic component CGSHiEE_02680 144 COG4531 ZnuA, ABC-type Zn2+ transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 148825697 Common - citrate lyase alpha chain CGSHiEE_03200 31 COG3051 CitF, Citrate lyase, alpha subunit Energy production and conversion 148826479 Common ndk nucleoside diphosphate kinase CGSHiEE_07650 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 148825341 Common - scaffold protein CGSHiEE_01125 165 COG0316 IscA, Uncharacterized conserved protein Function unknown 148826018 Common - 3-hydroxydecanoyl-(acyl carrier protein) dehydratase CGSHiEE_04985 81 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 148825165 Common - DNA-binding transcriptional regulator AsnC CGSHiEE_00185 182 COG1218 CysQ, 3'-Phosphoadenosine 5'-phosphosulfate (PAPS) 3'-phosphatase Inorganic ion transport and metabolism 148826255 Common - peptidoglycan synthetase FtsI CGSHiEE_06390 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 148826739 Common - RNA polymerase sigma factor RpoE CGSHiEE_09090 175 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 148826702 Pathogen - hypothetical protein CGSHiEE_08885 1 None None None 148826526 Common - putative soluble lytic murein transglycosylase CGSHiEE_07915 163 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 148825502 Common cysE serine acetyltransferase CGSHiEE_02005 205 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 148825866 Common nusA transcription elongation factor NusA CGSHiEE_04155 217 COG0195 NusA, Transcription elongation factor Transcription 148825282 Common - competence protein B CGSHiEE_00800 4 COG3166 PilN, Tfp pilus assembly protein PilN Cell motility and secretion / Intracellular trafficking and secretion 148826717 Common - putative LysR-family transcriptional regulator CGSHiEE_08960 188 COG0583 LysR, Transcriptional regulator Transcription 148826127 Common - hypothetical protein CGSHiEE_05650 9 COG3767 COG3767, Uncharacterized low-complexity protein Function unknown 148825320 Common - cyclic 3',5'-adenosine monophosphate phosphodiesterase CGSHiEE_01000 72 COG1409 Icc, Predicted phosphohydrolases General function prediction only 148826291 Common - thiol-disulfide interchange protein CGSHiEE_06590 134 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 148825673 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase CGSHiEE_03065 125 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 148825874 Common tyrA bifunctional chorismate mutase/prephenate dehydrogenase CGSHiEE_04195 101 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 148825724 Common lldD L-lactate dehydrogenase CGSHiEE_03345 123 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 148825351 Common - hypothetical protein CGSHiEE_01175 54 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 148826363 Common leuD isopropylmalate isomerase small subunit CGSHiEE_07020 209 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 148825528 Pathogen - hypothetical protein CGSHiEE_02180 1 None None None 148825782 Common - 3-deoxy-D-manno-octulosonate 8-phosphate phosphatase CGSHiEE_03665 102 COG1778 COG1778, Low specificity phosphatase (HAD superfamily) General function prediction only 148825878 Common - predicted selenocysteine lyase CGSHiEE_04215 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 148826641 Common clpX ATP-dependent protease ATP-binding subunit CGSHiEE_08550 239 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 148825301 Common - ATP-dependent RNA helicase SrmB CGSHiEE_00905 128 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148825643 Common - hypothetical protein CGSHiEE_02905 47 COG2833 COG2833, Uncharacterized protein conserved in bacteria Function unknown 148825329 Common - outer membrane protein CGSHiEE_01055 29 COG3065 Slp, Starvation-inducible outer membrane lipoprotein Cell envelope biogenesis, outer membrane 148825940 Common - hypothetical protein CGSHiEE_04575 18 None None None 148825384 Pathogen - hypothetical protein CGSHiEE_01340 2 None None None 148825426 Common rho transcription termination factor Rho CGSHiEE_01580 206 COG1158 Rho, Transcription termination factor Transcription 148826513 Common - hypothetical protein CGSHiEE_07850 19 COG3082 COG3082, Uncharacterized protein conserved in bacteria Function unknown 148825573 Common rpmF 50S ribosomal protein L32 CGSHiEE_02490 66 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 148826540 Common - hypothetical protein CGSHiEE_07985 35 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 148825257 Common - coproporphyrinogen III oxidase CGSHiEE_00675 210 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 148826065 Common - predicted component of anaerobic dehydrogenase CGSHiEE_05295 14 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 148825334 Common - colicin uptake protein TolR CGSHiEE_01080 98 COG0848 ExbD, Biopolymer transport protein Intracellular trafficking and secretion 148825739 Common - methionine aminopeptidase CGSHiEE_03440 248 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 148825705 Common rnc ribonuclease III CGSHiEE_03240 217 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 148825933 Pathogen - hypothetical protein CGSHiEE_04540 1 COG4185 COG4185, Uncharacterized protein conserved in bacteria Function unknown 148826315 Common - CTP synthetase CGSHiEE_06720 67 COG2363 COG2363, Uncharacterized small membrane protein Function unknown 148826278 Common - conserved hypothetical Na(+)/H(+) antiporter CGSHiEE_06525 61 COG1757 NhaC, Na+/H+ antiporter Energy production and conversion 148825450 Common djlA DnaJ-like membrane chaperone protein CGSHiEE_01700 208 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 148826634 Common - hypothetical protein CGSHiEE_08515 130 COG1739 COG1739, Uncharacterized conserved protein Function unknown 148825780 Pathogen - hypothetical protein CGSHiEE_03655 1 COG3025 COG3025, Uncharacterized conserved protein Function unknown 148826081 Common - HemK CGSHiEE_05375 218 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 148826462 Common - ATP-dependent RNA helicase RhlB CGSHiEE_07565 233 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 148825444 Common rbn ribonuclease BN CGSHiEE_01670 143 COG1295 Rbn, Predicted membrane protein Function unknown 148826047 Common - dihydrodipicolinate reductase CGSHiEE_05150 196 COG0611 ThiL, Thiamine monophosphate kinase Coenzyme metabolism 148825816 Common rpsA 30S ribosomal protein S1 CGSHiEE_03845 4 COG3771 COG3771, Predicted membrane protein Function unknown 148825595 Common - DNA polymerase III subunit epsilon CGSHiEE_02600 188 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 148825881 Common - hypothetical protein CGSHiEE_04230 81 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 148826192 Common - ribosomal large subunit pseudouridine synthase B CGSHiEE_06045 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 148825581 Common - HflK CGSHiEE_02530 214 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 148825315 Common - pyridoxine kinase CGSHiEE_00975 213 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 148825824 Common - adenine phosphoribosyltransferase CGSHiEE_03885 191 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 148825861 Common - putative NAD(P)H nitroreductase CGSHiEE_04130 90 COG0778 NfnB, Nitroreductase Energy production and conversion 148826425 Common - putative prophage integrase CGSHiEE_07360 12 None None None 148825140 Common - 30S ribosomal protein S7 CGSHiEE_00060 247 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 148825799 Common nrdB ribonucleotide-diphosphate reductase subunit beta CGSHiEE_03750 151 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 148825512 Common - hypothetical protein CGSHiEE_02065 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 148825663 Pathogen - hypothetical protein CGSHiEE_03015 1 None None None 148826685 Common - putative ferric siderophore receptor CGSHiEE_08790 90 COG4774 Fiu, Outer membrane receptor for monomeric catechols Inorganic ion transport and metabolism 148826336 Common - twin-argninine leader-binding protein DmsD CGSHiEE_06855 27 COG3381 TorD, Uncharacterized component of anaerobic dehydrogenases General function prediction only 148825148 Common - hypothetical protein CGSHiEE_00100 46 COG2900 SlyX, Uncharacterized protein conserved in bacteria Function unknown 148826682 Common glpC sn-glycerol-3-phosphate dehydrogenase subunit C CGSHiEE_08775 43 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 148826498 Common - 23S rRNA (guanosine-2'-O-)-methyltransferase CGSHiEE_07755 25 COG3027 COG3027, Uncharacterized protein conserved in bacteria Function unknown 148826423 Common glyQ glycyl-tRNA synthetase subunit alpha CGSHiEE_07350 48 COG2852 COG2852, Uncharacterized protein conserved in bacteria Function unknown 148825519 Common - hypothetical protein CGSHiEE_02100 56 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 148826072 Common bioD dithiobiotin synthetase CGSHiEE_05330 156 COG0132 BioD, Dethiobiotin synthetase Coenzyme metabolism 148826233 Common - proton glutamate symport protein CGSHiEE_06270 151 COG1823 COG1823, Predicted Na+/dicarboxylate symporter General function prediction only 148825402 Common - transposase CGSHiEE_01460 147 COG2801 Tra5, Transposase and inactivated derivatives DNA replication, recombination, and repair 148826249 Common murG N-acetylglucosaminyl transferase CGSHiEE_06360 210 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 148825267 Common - hypothetical protein CGSHiEE_00725 15 None None None 148826590 Common - hypothetical protein CGSHiEE_08255 209 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 148825854 Common - DNA gyrase subunit A CGSHiEE_04075 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 148826624 Common - UDP-2,3-diacylglucosamine hydrolase CGSHiEE_08455 63 COG2132 SufI, Putative multicopper oxidases Secondary metabolites biosynthesis, transport, and catabolism 148825753 Common - predicted permease CGSHiEE_03510 112 COG0795 COG0795, Predicted permeases General function prediction only 148826750 Pathogen - hypothetical protein CGSHiEE_09145 1 None None None 148825255 Common - D-3-phosphoglycerate dehydrogenase CGSHiEE_00665 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 148825760 Common - putative UDP-galactose--lipooligosaccharide galactosyltransferase CGSHiEE_03555 118 COG1216 COG1216, Predicted glycosyltransferases General function prediction only 148826385 Common rpsT 30S ribosomal protein S20 CGSHiEE_07130 159 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 148825395 Common - hypothetical protein CGSHiEE_01425 10 COG4456 VagC, Virulence-associated protein and related proteins Function unknown 148825701 Common - uracil-DNA glycosylase CGSHiEE_03220 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 148826138 Common - aminopeptidase N CGSHiEE_05725 161 COG0308 PepN, Aminopeptidase N Amino acid transport and metabolism 148825417 Common - hypothetical protein CGSHiEE_01535 205 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 148826167 Common - ABC-type transport system, periplasmic component, involved in antimicrobial peptide resistance CGSHiEE_05880 183 COG4166 OppA, ABC-type oligopeptide transport system, periplasmic component Amino acid transport and metabolism 148826656 Common truD tRNA pseudouridine synthase D CGSHiEE_08635 85 COG0585 COG0585, Uncharacterized conserved protein Function unknown 148826285 Common ligA NAD-dependent DNA ligase LigA CGSHiEE_06560 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 148826165 Common - putative type II restriction endonuclease CGSHiEE_05870 29 COG3440 COG3440, Predicted restriction endonuclease Defense mechanisms 148826124 Common - hypothetical protein CGSHiEE_05635 9 COG5566 COG5566, Uncharacterized conserved protein Function unknown 148826458 Common - cell division protein CGSHiEE_07535 19 COG3087 FtsN, Cell division protein Cell division and chromosome partitioning 148825691 Common - hypothetical protein CGSHiEE_03170 24 COG2921 COG2921, Uncharacterized conserved protein Function unknown 148826655 Common surE stationary phase survival protein SurE CGSHiEE_08630 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 148825710 Common - formate dehydrogenase gamma subunit CGSHiEE_03275 71 COG2864 FdnI, Cytochrome b subunit of formate dehydrogenase Energy production and conversion 148826223 Common - conserved glutaredoxin-related protein CGSHiEE_06220 126 COG0278 COG0278, Glutaredoxin-related protein Posttranslational modification, protein turnover, chaperones 148826295 Common - heme exporter protein C CGSHiEE_06610 125 COG0755 CcmC, ABC-type transport system involved in cytochrome c biogenesis, permease component Posttranslational modification, protein turnover, chaperones 148825212 Common - potassium-tellurite ethidium and proflavin transporter CGSHiEE_00440 94 COG1720 COG1720, Uncharacterized conserved protein Function unknown 148825273 Common fruK 1-phosphofructokinase CGSHiEE_00755 117 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 148826551 Pathogen - 1-deoxy-D-xylulose 5-phosphate reductoisomerase CGSHiEE_08040 4 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 148826530 Common - intracellular septation protein A CGSHiEE_07935 4 None None None 148825556 Common - Na(+)-translocating NADH-quinone reductase subunit E CGSHiEE_02375 76 COG2209 NqrE, Na+-transporting NADH:ubiquinone oxidoreductase, subunit NqrE Energy production and conversion 148825155 Common - ribulose-phosphate 3-epimerase CGSHiEE_00135 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 148826040 Common pheT phenylalanyl-tRNA synthetase subunit beta CGSHiEE_05115 232 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 148826215 Common artM arginine transporter permease subunit ArtM CGSHiEE_06170 5 COG3637 COG3637, Opacity protein and related surface antigens Cell envelope biogenesis, outer membrane 148825284 Common - competence protein D CGSHiEE_00810 3 None None None 148825558 Common - lipoprotein CGSHiEE_02385 137 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 148825614 Pathogen - hypothetical protein CGSHiEE_02730 1 None None None 148826013 Pathogen - insertion element IS1016 transposase CGSHiEE_04960 3 COG3676 COG3676, Transposase and inactivated derivatives DNA replication, recombination, and repair 148826562 Common rplR 50S ribosomal protein L18 CGSHiEE_08095 207 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 148825996 Common - bifunctional methionine sulfoxide reductase A/B protein CGSHiEE_04865 206 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 148826548 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase CGSHiEE_08025 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 148825986 Common rplM 50S ribosomal protein L13 CGSHiEE_04815 237 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 148826135 Common - sugar fermentation stimulation protein A CGSHiEE_05710 107 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 148826554 Common rpsD 30S ribosomal protein S4 CGSHiEE_08055 223 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 148826391 Common rumB 23S rRNA metyluridine methyltransferase CGSHiEE_07170 144 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 148825544 Common - Ferric uptake regulation protein CGSHiEE_02305 201 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 148825658 Pathogen - hypothetical protein CGSHiEE_02990 1 None None None 148825745 Common - phosphoenolpyruvate-protein phosphotransferase CGSHiEE_03470 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 148826523 Common - fumarate reductase subunit D CGSHiEE_07900 21 COG3080 FrdD, Fumarate reductase subunit D Energy production and conversion 148825945 Common - hypothetical protein CGSHiEE_04600 18 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 148825430 Common - mercuric ion scavenger protein CGSHiEE_01600 50 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 148826241 Common - hypothetical protein CGSHiEE_06310 129 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 148826257 Common mraW S-adenosyl-methyltransferase MraW CGSHiEE_06400 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 148825735 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase CGSHiEE_03420 197 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 148825805 Common - putative lipoprotein CGSHiEE_03780 42 COG3107 LppC, Putative lipoprotein General function prediction only 148825337 Common - outer membrane protein P6 precursor CGSHiEE_01095 149 COG2885 OmpA, Outer membrane protein and related peptidoglycan-associated (lipo)proteins Cell envelope biogenesis, outer membrane 148825531 Common - NAD nucleotidase CGSHiEE_02210 128 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 148825234 Common gidB glucose-inhibited division protein B CGSHiEE_00550 162 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 148826436 Common - hypothetical protein CGSHiEE_07415 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 148826188 Common - phosphate acetyltransferase CGSHiEE_06025 167 COG0280 Pta, Phosphotransacetylase Energy production and conversion 148826181 Common lysS lysyl-tRNA synthetase CGSHiEE_05980 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 148825492 Common - putative transcriptional regulator CGSHiEE_01955 155 COG1522 Lrp, Transcriptional regulators Transcription 148826671 Common tpiA triosephosphate isomerase CGSHiEE_08710 21 None None None 148826110 Common - hypothetical protein CGSHiEE_05565 6 None None None 148825396 Common - S-adenosyl-L-methionine-dependent methyltransferase CGSHiEE_01430 50 COG4106 Tam, Trans-aconitate methyltransferase General function prediction only 148825262 Common - stationary-phase survival protein SurA CGSHiEE_00700 142 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 148825876 Common - Zn-ribbon-containing, possibly nucleic-acid-binding protein CGSHiEE_04205 13 COG5595 COG5595, Zn-ribbon-containing, possibly nucleic-acid-binding protein General function prediction only 148826678 Common glpA sn-glycerol-3-phosphate dehydrogenase subunit A CGSHiEE_08755 161 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 148826643 Common tig trigger factor CGSHiEE_08560 216 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 148825843 Common - hypothetical protein CGSHiEE_04010 48 COG3549 HigB, Plasmid maintenance system killer protein General function prediction only 148825455 Common - hypothetical protein CGSHiEE_01725 170 COG0344 COG0344, Predicted membrane protein Function unknown 148825287 Common - predicted gluconate transport-associated protein CGSHiEE_00825 59 COG0694 COG0694, Thioredoxin-like proteins and domains Posttranslational modification, protein turnover, chaperones 148826369 Common - hypothetical protein CGSHiEE_07050 4 None None None 148825743 Common - ribosome-associated GTPase CGSHiEE_03460 163 COG1162 COG1162, Predicted GTPases General function prediction only 148825291 Common - D-fructose-6-phosphate amidotransferase CGSHiEE_00845 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 148826493 Common - hypothetical protein CGSHiEE_07730 75 COG1738 COG1738, Uncharacterized conserved protein Function unknown 148825460 Common - 3-deoxy-D-manno-octulosonic-acid kinase CGSHiEE_01760 20 COG0478 COG0478, RIO-like serine/threonine protein kinase fused to N-terminal HTH domain Signal transduction mechanisms 148826444 Common - hypothetical protein CGSHiEE_07455 36 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 148826250 Common murG N-acetylglucosaminyl transferase CGSHiEE_06365 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 148825222 Common - DNA recombination protein RmuC CGSHiEE_00490 113 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 148826026 Common - predicted enzyme CGSHiEE_05025 52 COG0676 COG0676, Uncharacterized enzymes related to aldose 1-epimerase Carbohydrate transport and metabolism 148826417 Common eno phosphopyruvate hydratase CGSHiEE_07310 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 148825228 Common aphA acid phosphatase/phosphotransferase CGSHiEE_00520 12 COG3700 AphA, Acid phosphatase (class B) General function prediction only 148825790 Common moaD molybdopterin synthase small subunit CGSHiEE_03705 53 COG2995 PqiA, Uncharacterized paraquat-inducible protein A Function unknown 148826433 Common holA DNA polymerase III subunit delta CGSHiEE_07400 65 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 148825514 Common - glycerol-3-phosphate regulon repressor CGSHiEE_02075 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 148826393 Common - hypothetical protein CGSHiEE_07180 26 COG3089 COG3089, Uncharacterized protein conserved in bacteria Function unknown 148825755 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase CGSHiEE_03520 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 148826154 Common - 50S ribosomal protein L25 CGSHiEE_05815 146 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 148826199 Pathogen - hypothetical protein CGSHiEE_06080 1 None None None 148826475 Common rplU 50S ribosomal protein L21 CGSHiEE_07630 210 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 148825218 Common - D-ribose transporter subunit RbsB CGSHiEE_00470 126 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148826287 Pathogen - hypothetical protein CGSHiEE_06570 2 None None None 148826002 Pathogen - hypothetical protein CGSHiEE_04895 1 None None None 148826606 Common dapF diaminopimelate epimerase CGSHiEE_08355 203 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 148825308 Common hfq RNA-binding protein Hfq CGSHiEE_00940 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 148826301 Common - conserved ABC-type transport system protein, periplasmic component CGSHiEE_06640 101 COG1463 Ttg2C, ABC-type transport system involved in resistance to organic solvents, periplasmic component Secondary metabolites biosynthesis, transport, and catabolism 148826503 Common - molybdopterin-guanine dinucleotide biosynthesis protein B CGSHiEE_07790 88 COG1763 MobB, Molybdopterin-guanine dinucleotide biosynthesis protein Coenzyme metabolism 148826383 Common - naphthoate synthase CGSHiEE_07120 180 COG0447 MenB, Dihydroxynaphthoic acid synthase Coenzyme metabolism 148826746 Pathogen - hypothetical protein CGSHiEE_09125 1 None None None 148825963 Common - dihydroorotate dehydrogenase 2 CGSHiEE_04690 20 None None None 148826042 Pathogen - hypothetical protein CGSHiEE_05125 2 None None None 148825484 Common - predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein CGSHiEE_01915 87 COG4623 COG4623, Predicted soluble lytic transglycosylase fused to an ABC-type amino acid-binding protein Cell envelope biogenesis, outer membrane 148825189 Common - urease accessory protein UreF CGSHiEE_00305 84 COG0830 UreF, Urease accessory protein UreF Posttranslational modification, protein turnover, chaperones 148825193 Common aspA aspartate ammonia-lyase CGSHiEE_00325 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 148825955 Pathogen - hypothetical protein CGSHiEE_04650 1 None None None 148826715 Common - predicted periplasmic lipoprotein CGSHiEE_08950 4 COG5645 COG5645, Predicted periplasmic lipoprotein General function prediction only 148826213 Common artM arginine transporter permease subunit ArtM CGSHiEE_06160 171 COG4160 ArtM, ABC-type arginine/histidine transport system, permease component Amino acid transport and metabolism 148825504 Common - possible di- and tricarboxylate transporter CGSHiEE_02015 149 COG0471 CitT, Di- and tricarboxylate transporters Inorganic ion transport and metabolism 148826093 Pathogen - hypothetical protein CGSHiEE_05435 1 None None None 148825891 Common - hypothetical protein CGSHiEE_04280 59 COG2230 Cfa, Cyclopropane fatty acid synthase and related methyltransferases Cell envelope biogenesis, outer membrane 148825636 Common - threonine synthase CGSHiEE_02850 185 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 148826713 Common - 3-deoxy-D-manno-octulosonic-acid transferase CGSHiEE_08940 128 COG1519 KdtA, 3-deoxy-D-manno-octulosonic-acid transferase Cell envelope biogenesis, outer membrane 148826700 Pathogen - hypothetical protein CGSHiEE_08875 1 None None None 148825483 Pathogen - hypothetical protein CGSHiEE_01910 1 None None None 148825676 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase CGSHiEE_03080 77 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 148826129 Common - putative phosphate permease CGSHiEE_05670 174 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 148826617 Common - threonine dehydratase CGSHiEE_08420 222 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 148825317 Common - methylated-DNA-protein-cysteine methyltransferase CGSHiEE_00985 210 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 148825695 Common - citrate lyase subunit gamma CGSHiEE_03190 26 COG3052 CitD, Citrate lyase, gamma subunit Energy production and conversion 148826205 Common uvrD DNA-dependent helicase II CGSHiEE_06120 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148826293 Common - cytochrome c-type biogenesis protein CcmE CGSHiEE_06600 94 COG2332 CcmE, Cytochrome c-type biogenesis protein CcmE Posttranslational modification, protein turnover, chaperones 148825715 Common - hypothetical protein CGSHiEE_03300 191 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 148826662 Common - hypothetical protein CGSHiEE_08665 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 148825356 Common - putative periplasmic chelated iron binding protein CGSHiEE_01200 179 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 148825509 Common fucI L-fucose isomerase CGSHiEE_02050 19 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 148826730 Common - tryptophanyl-tRNA synthetase CGSHiEE_09035 232 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148826059 Common - 3-oxoacyl-(acyl carrier protein) synthase I CGSHiEE_05245 209 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148826119 Common - HMW1C, putative glycosyltransferase involved in glycosylation of HMW1A and HMW2A CGSHiEE_05610 23 COG3914 Spy, Predicted O-linked N-acetylglucosamine transferase, SPINDLY family Posttranslational modification, protein turnover, chaperones 148826572 Common rpsC 30S ribosomal protein S3 CGSHiEE_08145 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 148826709 Common aroE shikimate 5-dehydrogenase CGSHiEE_08920 219 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 148826332 Common - hypothetical protein CGSHiEE_06825 6 None None None 148826359 Common dnaA chromosomal replication initiation protein CGSHiEE_07000 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 148825922 Common - ferritin like protein 1 CGSHiEE_04475 84 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 148825202 Common - fructose-bisphosphate aldolase CGSHiEE_00370 145 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 148826470 Common dipZ thiol:disulfide interchange protein precursor CGSHiEE_07605 124 COG4232 COG4232, Thiol:disulfide interchange protein Posttranslational modification, protein turnover, chaperones / Energy production and conversion 148826488 Common - hypothetical protein CGSHiEE_07695 183 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148826693 Common - flavodoxin CGSHiEE_08830 70 COG0716 FldA, Flavodoxins Energy production and conversion 148826039 Common rpmI 50S ribosomal protein L35 CGSHiEE_05110 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 148826079 Common - 2-dehydro-3-deoxyphosphooctonate aldolase CGSHiEE_05365 186 COG2877 KdsA, 3-deoxy-D-manno-octulosonic acid (KDO) 8-phosphate synthase Cell envelope biogenesis, outer membrane 148825608 Common mltA murein transglycosylase A CGSHiEE_02690 92 COG2821 MltA, Membrane-bound lytic murein transglycosylase Cell envelope biogenesis, outer membrane 148826373 Common fis DNA-binding protein Fis CGSHiEE_07070 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 148825624 Common - heat shock protein 90 CGSHiEE_02780 109 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 148826404 Common - formamidopyrimidine-DNA glycosylase CGSHiEE_07235 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 148825180 Common - primosomal replication protein N CGSHiEE_00260 24 COG2965 PriB, Primosomal replication protein N DNA replication, recombination, and repair 148826695 Pathogen - hypothetical protein CGSHiEE_08850 1 None None None