Thermotoga petrophila RKU-1, complete genome NC_009486 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 148270850 Nonpathogen - hypothetical protein Tpet_1729 1 None None None 148270360 Nonpathogen - hypothetical protein Tpet_1230 1 None None None 148269919 Common - anthranilate phosphoribosyltransferase Tpet_0784 241 COG0547 TrpD, Anthranilate phosphoribosyltransferase Amino acid transport and metabolism 148269237 Common - cell division protein FtsA Tpet_0092 142 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 148269806 Common smpB SsrA-binding protein Tpet_0670 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 148270408 Nonpathogen - hypothetical protein Tpet_1278 1 None None None 148270112 Common - metal dependent phosphohydrolase Tpet_0978 128 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 148270545 Nonpathogen - protein of unknown function DUF369 Tpet_1416 10 COG2164 COG2164, Uncharacterized conserved protein Function unknown 148270439 Common - ribosomal protein S5 Tpet_1309 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 148269724 Common - orotidine 5'-phosphate decarboxylase Tpet_0587 106 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 148270857 Nonpathogen - ATPase Tpet_1739 16 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 148269537 Common - RNA chaperone Hfq Tpet_0395 127 COG1923 Hfq, Uncharacterized host factor I protein General function prediction only 148270600 Common - ABC-2 type transporter Tpet_1474 39 COG1511 COG1511, Predicted membrane protein Function unknown 148270870 Nonpathogen - hypothetical protein Tpet_1753 1 None None None 148269244 Common - PfkB domain protein Tpet_0099 93 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 148270410 Common - sun protein Tpet_1280 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 148269644 Common - oxidoreductase domain protein Tpet_0506 182 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 148269910 Common - ribosomal protein L32 Tpet_0775 80 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 148270838 Common - Mannose-1-phosphate guanylyltransferase (GDP) Tpet_1717 161 COG0836 {ManC}, Mannose-1-phosphate guanylyltransferase Cell envelope biogenesis, outer membrane 148270369 Common - ApbE family lipoprotein Tpet_1239 142 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 148270034 Common - methyl-accepting chemotaxis sensory transducer Tpet_0900 148 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148270146 Nonpathogen - PASTA domain containing protein Tpet_1012 2 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 148270432 Common - ribosomal protein L14 Tpet_1302 248 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 148269487 Common - DNA polymerase III, alpha subunit Tpet_0342 219 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 148270792 Common - carbohydrate kinase, FGGY Tpet_1671 83 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148270025 Common - ROK family protein Tpet_0891 141 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148270455 Nonpathogen - hypothetical protein Tpet_1325 4 None None None 148270401 Common - dihydrodipicolinate synthase Tpet_1271 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 148269228 Common - protein of unknown function DUF163 Tpet_0083 163 COG1576 COG1576, Uncharacterized conserved protein Function unknown 148270800 Common - extracellular solute-binding protein, family 1 Tpet_1679 32 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148270440 Common - ribosomal protein L30 Tpet_1310 124 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 148269777 Common - hypothetical protein Tpet_0641 13 None None None 148270833 Common hisH imidazole glycerol phosphate synthase subunit HisH Tpet_1712 215 COG0118 HisH, Glutamine amidotransferase Amino acid transport and metabolism 148269716 Nonpathogen - hypothetical protein Tpet_0579 3 None None None 148269840 Common fliG flagellar motor switch protein G Tpet_0704 125 COG1536 FliG, Flagellar motor switch protein Cell motility and secretion 148269794 Common - histone family protein DNA-binding protein Tpet_0658 210 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 148269480 Common - UDP-glucose 6-dehydrogenase Tpet_0335 205 COG0677 WecC, UDP-N-acetyl-D-mannosaminuronate dehydrogenase Cell envelope biogenesis, outer membrane 148269630 Common - Beta-glucuronidase Tpet_0490 75 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 148270449 Common rpsD 30S ribosomal protein S4 Tpet_1319 243 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 148270191 Common - 1-deoxy-D-xylulose-5-phosphate synthase Tpet_1058 225 COG1154 Dxs, Deoxyxylulose-5-phosphate synthase Coenzyme metabolism / Lipid metabolism 148269658 Common - integral membrane sensor signal transduction histidine kinase Tpet_0520 221 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148270314 Nonpathogen - Uncharacterized protein-like protein Tpet_1184 2 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 148269521 Common - Malate dehydrogenase (oxaloacetate-decarboxylating) Tpet_0379 202 COG0281 SfcA, Malic enzyme Energy production and conversion 148269403 Common - flagellar hook capping protein Tpet_0258 109 COG1843 FlgD, Flagellar hook capping protein Cell motility and secretion 148270813 Common - Stage V sporulation protein S Tpet_1692 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 148269759 Common - 6-phosphofructokinase Tpet_0623 160 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 148269829 Common - UDP-N-acetylmuramate--alanine ligase Tpet_0693 210 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 148269213 Nonpathogen - preprotein translocase, YajC subunit Tpet_0068 3 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 148270091 Common - ROK family protein Tpet_0957 98 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148270104 Common - glycoside hydrolase, family 4 Tpet_0970 50 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 148270916 Nonpathogen - hypothetical protein Tpet_1800 10 None None None 148270450 Common - DNA-directed RNA polymerase subunit alpha Tpet_1320 218 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 148270396 Nonpathogen - Rubrerythrin Tpet_1266 13 COG1633 COG1633, Uncharacterized conserved protein Function unknown 148269386 Common - Triose-phosphate isomerase Tpet_0241 219 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 148270820 Common - competence protein ComEA helix-hairpin-helix repeat protein Tpet_1699 166 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 148269199 Common - ATPase AAA-2 domain protein Tpet_0054 215 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 148270087 Common - alpha amylase, catalytic region Tpet_0953 159 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 148269255 Common - exporter of the RND superfamily-like protein Tpet_0110 89 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 148270912 Common - hypothetical protein Tpet_1796 18 COG4923 COG4923, Uncharacterized conserved protein Function unknown 148269506 Common - carbamoyl phosphate synthase small subunit Tpet_0362 234 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 148270119 Common - Guanylate kinase Tpet_0985 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 148269584 Nonpathogen - hypothetical protein Tpet_0444 2 None None None 148270610 Common - exporter of the RND superfamily-like protein Tpet_1486 84 COG1033 COG1033, Predicted exporters of the RND superfamily General function prediction only 148269925 Common - beta-lactamase domain protein Tpet_0790 161 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148270879 Common - DsrH family protein Tpet_1762 3 COG2168 DsrH, Uncharacterized conserved protein involved in oxidation of intracellular sulfur Inorganic ion transport and metabolism 148269862 Common - ATPase AAA-2 domain protein Tpet_0726 225 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 148270675 Common - extracellular solute-binding protein, family 1 Tpet_1552 110 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 148270304 Nonpathogen - hypothetical protein Tpet_1174 1 None None None 148270929 Common - Uncharacterized protein-like protein Tpet_1813 32 COG3864 COG3864, Uncharacterized protein conserved in bacteria Function unknown 148269551 Common - phage SPO1 DNA polymerase-related protein Tpet_0411 154 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 148269930 Common - peptidase dimerisation domain protein Tpet_0795 187 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 148270809 Common - hypothetical protein Tpet_1688 11 None None None 148269615 Common - small GTP-binding protein Tpet_0475 228 COG1160 COG1160, Predicted GTPases General function prediction only 148270227 Common - metal dependent phosphohydrolase Tpet_1097 29 COG1353 COG1353, Predicted hydrolase of the HD superfamily (permuted catalytic motifs) General function prediction only 148269965 Common - type II secretion system protein Tpet_0830 146 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 148269874 Nonpathogen - Activator of Hsp90 ATPase 1 family protein Tpet_0739 5 COG3832 COG3832, Uncharacterized conserved protein Function unknown 148269651 Common - diacylglycerol kinase Tpet_0513 56 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 148270758 Nonpathogen - hypothetical protein Tpet_1636 1 None None None 148269675 Common - nitroreductase Tpet_0537 229 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148270619 Common - ABC transporter related Tpet_1495 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 148269785 Common - periplasmic binding protein/LacI transcriptional regulator Tpet_0649 125 COG1609 PurR, Transcriptional regulators Transcription 148269902 Common - prolipoprotein diacylglyceryl transferase Tpet_0767 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 148269974 Nonpathogen - anti-sigma-28 factor, FlgM Tpet_0839 2 COG2747 FlgM, Negative regulator of flagellin synthesis (anti-sigma28 factor) Transcription / Cell motility and secretion / Intracellular trafficking and secretion 148270531 Nonpathogen - hypothetical protein Tpet_1402 4 None None None 148270042 Common - pyruvate/ketoisovalerate oxidoreductase, gamma subunit Tpet_0908 77 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 148270214 Common - CRISPR-associated helicase Cas3 Tpet_1084 100 COG1203 COG1203, Predicted helicases General function prediction only 148269731 Common - short-chain dehydrogenase/reductase SDR Tpet_0594 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148270474 Common - transcription-repair coupling factor Tpet_1344 239 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 148269150 Common - carbohydrate kinase, YjeF related protein Tpet_0005 222 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 148269953 Common - nuclease (RecB family)-like protein Tpet_0818 16 COG2251 COG2251, Predicted nuclease (RecB family) General function prediction only 148269159 Common - MazG family protein Tpet_0014 156 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 148270747 Nonpathogen - hypothetical protein Tpet_1625 1 None None None 148269620 Nonpathogen - hypothetical protein Tpet_0480 8 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 148269876 Common - Nitrilase/cyanide hydratase and apolipoprotein N-acyltransferase Tpet_0741 208 COG0388 COG0388, Predicted amidohydrolase General function prediction only 148270357 Common - signal recognition particle protein Tpet_1227 246 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 148270799 Common - FG-GAP repeat protein Tpet_1678 15 None None None 148269920 Common - Indole-3-glycerol-phosphate synthase Tpet_0785 219 COG0134 TrpC, Indole-3-glycerol phosphate synthase Amino acid transport and metabolism 148269738 Common - alkylhydroperoxidase like protein, AhpD family Tpet_0601 40 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 148270417 Common rpsL 30S ribosomal protein S12 Tpet_1287 246 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 148270829 Common - ATP phosphoribosyltransferase Tpet_1708 210 COG0040 HisG, ATP phosphoribosyltransferase Amino acid transport and metabolism 148269632 Common - fumarate reductase/succinate dehydrogenase flavoprotein domain protein Tpet_0493 39 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 148269629 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_0489 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 148269810 Common - DNA protecting protein DprA Tpet_0674 210 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 148269292 Nonpathogen - hypothetical protein Tpet_0147 4 None None None 148269762 Common - transcriptional regulator, PadR-like family Tpet_0626 75 COG1695 COG1695, Predicted transcriptional regulators Transcription 148270507 Common - SufBD protein Tpet_1377 90 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 148270922 Common - amidohydrolase Tpet_1806 165 COG0402 SsnA, Cytosine deaminase and related metal-dependent hydrolases Nucleotide transport and metabolism / General function prediction only 148269271 Common - Beta-ketoacyl synthase-like protein Tpet_0126 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148269819 Nonpathogen - hypothetical protein Tpet_0683 4 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 148270284 Nonpathogen - hypothetical protein Tpet_1154 4 None None None 148269494 Common - Uncharacterized protein-like protein Tpet_0349 15 COG1655 COG1655, Uncharacterized protein conserved in bacteria Function unknown 148269223 Common - chaperone protein DnaJ Tpet_0078 236 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 148269532 Common - extracellular solute-binding protein, family 5 Tpet_0390 193 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148269852 Common - pyruvate kinase Tpet_0716 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 148270138 Common - protein of unknown function DUF199 Tpet_1004 53 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 148269439 Nonpathogen - hypothetical protein Tpet_0294 2 None None None 148269981 Common - ABC transporter related Tpet_0846 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 148270538 Common - Phosphoglycerate mutase Tpet_1409 184 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 148270272 Common - protein of unknown function DUF503 Tpet_1142 34 COG1550 COG1550, Uncharacterized protein conserved in bacteria Function unknown 148269267 Common - O-antigen polymerase Tpet_0122 13 COG3307 RfaL, Lipid A core - O-antigen ligase and related enzymes Cell envelope biogenesis, outer membrane 148269381 Common - trigger factor, C-terminal domain protein Tpet_0236 79 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 148270712 Nonpathogen - hypothetical protein Tpet_1590 4 COG2267 PldB, Lysophospholipase Lipid metabolism 148270668 Common - ROK family protein Tpet_1544 116 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148269278 Common - PfkB domain protein Tpet_0133 9 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148269590 Common - integral membrane protein-like protein Tpet_0450 22 COG0392 COG0392, Predicted integral membrane protein Function unknown 148269906 Common - Prephenate dehydratase Tpet_0771 213 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 148270016 Common - 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase Tpet_0882 201 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 148270513 Common - aminotransferase, class V Tpet_1383 171 COG0075 COG0075, Serine-pyruvate aminotransferase/archaeal aspartate aminotransferase Amino acid transport and metabolism 148270296 Nonpathogen - UvrB/UvrC protein Tpet_1166 3 None None None 148270005 Nonpathogen - hypothetical protein Tpet_0870 1 None None None 148269231 Common - PEGA domain protein Tpet_0086 23 None None None 148269828 Common - UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase Tpet_0692 210 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 148269215 Common - riboflavin biosynthesis protein RibF Tpet_0070 211 COG0196 RibF, FAD synthase Coenzyme metabolism 148270348 Common - tRNA pseudouridine synthase A Tpet_1218 237 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 148270371 Common - AMMECR1 domain protein Tpet_1241 76 COG2078 AMMECR1, Uncharacterized conserved protein Function unknown 148270880 Common - SirA family protein Tpet_1763 14 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 148270243 Common - riboflavin biosynthesis protein RibD Tpet_1113 226 COG0117 RibD, Pyrimidine deaminase Coenzyme metabolism 148270661 Common - ABC transporter related Tpet_1537 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 148269604 Common - ribosomal protein L10 Tpet_0464 201 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 148270330 Common - Cobyrinic acid a,c-diamide synthase Tpet_1200 228 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148269424 Common - phospholipase D/Transphosphatidylase Tpet_0279 50 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 148270254 Common - xylose isomerase Tpet_1124 69 COG2115 XylA, Xylose isomerase Carbohydrate transport and metabolism 148270376 Common - single-stranded-DNA-specific exonuclease RecJ Tpet_1246 193 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 148270842 Common - hypothetical protein Tpet_1721 25 COG1277 NosY, ABC-type transport system involved in multi-copper enzyme maturation, permease component General function prediction only 148270849 Nonpathogen - hypothetical protein Tpet_1728 2 None None None 148269431 Common - peptidase C11, clostripain Tpet_0286 13 None None None 148269180 Common - CBS domain containing protein Tpet_0035 18 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 148270059 Common - protein of unknown function UPF0047 Tpet_0925 140 COG0432 COG0432, Uncharacterized conserved protein Function unknown 148269708 Common - 3-dehydroquinate dehydratase Tpet_0571 170 COG0757 AroQ, 3-dehydroquinate dehydratase II Amino acid transport and metabolism 148269147 Common - tRNA (guanine-N(7)-)-methyltransferase Tpet_0002 193 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 148269351 Common - protein of unknown function UPF0047 Tpet_0206 121 COG0432 COG0432, Uncharacterized conserved protein Function unknown 148269842 Common - flagellar protein export ATPase FliI Tpet_0706 247 COG1157 FliI, Flagellar biosynthesis/type III secretory pathway ATPase Cell motility and secretion / Intracellular trafficking and secretion 148270220 Nonpathogen - hypothetical protein Tpet_1090 3 None None None 148269695 Common - MazG nucleotide pyrophosphohydrolase Tpet_0558 129 COG3956 COG3956, Protein containing tetrapyrrole methyltransferase domain and MazG-like (predicted pyrophosphatase) domain General function prediction only 148270765 Common - ABC-2 type transporter Tpet_1643 77 COG1668 NatB, ABC-type Na+ efflux pump, permease component Energy production and conversion / Inorganic ion transport and metabolism 148269750 Common - Alcohol dehydrogenase GroES domain protein Tpet_0614 203 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 148270325 Common - alanine racemase domain protein Tpet_1195 20 COG3457 COG3457, Predicted amino acid racemase Amino acid transport and metabolism 148270666 Common - Carbohydrate binding module 27 Tpet_1542 17 COG3934 COG3934, Endo-beta-mannanase Carbohydrate transport and metabolism 148269322 Common - glycoside hydrolase, family 4 Tpet_0177 51 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 148269939 Common - nitroreductase Tpet_0804 83 COG0778 NfnB, Nitroreductase Energy production and conversion 148270587 Nonpathogen - hypothetical protein Tpet_1458 1 None None None 148270235 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein Tpet_1105 240 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 148270564 Nonpathogen - hypothetical protein Tpet_1435 4 None None None 148270291 Nonpathogen - hypothetical protein Tpet_1161 1 None None None 148269586 Common - Nicotinic acid phosphoribosyltransferase-like protein Tpet_0446 77 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 148270891 Nonpathogen - PglZ domain Tpet_1775 3 COG5293 COG5293, Uncharacterized protein conserved in bacteria Function unknown 148270657 Common - Radical SAM domain protein Tpet_1533 80 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 148270175 Common - butyrate kinase Tpet_1041 151 COG3426 COG3426, Butyrate kinase Energy production and conversion 148270159 Common ruvB Holliday junction DNA helicase B Tpet_1025 215 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 148270497 Common - hydrogenase large subunit domain protein Tpet_1367 183 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 148270183 Common - transketolase Tpet_1050 224 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 148270044 Common - beta-lactamase domain protein Tpet_0910 46 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 148270280 Common - Dihydrofolate reductase-like protein Tpet_1150 66 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 148269363 Common - Patatin Tpet_0218 110 COG1752 RssA, Predicted esterase of the alpha-beta hydrolase superfamily General function prediction only 148270038 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase Tpet_0904 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148269669 Common - alkylhydroperoxidase like protein, AhpD family Tpet_0531 78 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 148270110 Nonpathogen - hypothetical protein Tpet_0976 1 None None None 148270598 Common - YcfA family protein Tpet_1471 14 COG1724 COG1724, Predicted periplasmic or secreted lipoprotein Cell motility and secretion 148269983 Common - glycoside hydrolase, family 3 domain protein Tpet_0848 153 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 148270423 Common rplD 50S ribosomal protein L4 Tpet_1293 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 148270898 Common - NCAIR mutase (PurE)-related protein-like protein Tpet_1782 72 COG1691 COG1691, NCAIR mutase (PurE)-related proteins General function prediction only 148269160 Common - PpiC-type peptidyl-prolyl cis-trans isomerase Tpet_0015 119 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 148269153 Common - OsmC family protein Tpet_0008 86 COG1765 COG1765, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 148270647 Common - phosphoribosylglycinamide formyltransferase Tpet_1523 228 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 148270263 Common - S-adenosylmethionine synthetase Tpet_1133 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 148269793 Common trmE tRNA modification GTPase TrmE Tpet_0657 227 COG0486 ThdF, Predicted GTPase General function prediction only 148270126 Common - peptidase A24A domain protein Tpet_0992 128 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148270547 Common - flagellar basal-body rod protein FlgC Tpet_1418 126 COG1558 FlgC, Flagellar basal body rod protein Cell motility and secretion 148270760 Common - putative monovalent cation/H+ antiporter subunit D Tpet_1638 210 COG0651 HyfB, Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit Energy production and conversion / Inorganic ion transport and metabolism 148270720 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_1598 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269395 Common - beta-lactamase domain protein Tpet_0250 88 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148269864 Common - protein of unknown function DUF355 Tpet_0728 33 COG1839 COG1839, Uncharacterized conserved protein Function unknown 148270170 Common - RNA methyltransferase, TrmH family, group 3 Tpet_1036 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 148269330 Common - glycosyl transferase, group 1 Tpet_0185 216 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148270700 Common - putative transcriptional regulator, Crp/Fnr family Tpet_1578 86 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 148270774 Common - histidyl-tRNA synthetase Tpet_1653 247 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148269379 Common - protein of unknown function DUF500 Tpet_0234 21 COG2930 COG2930, Uncharacterized conserved protein Function unknown 148269411 Common - cysteine synthase A Tpet_0266 221 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 148269169 Common - CheD, stimulates methylation of MCP protein Tpet_0024 87 COG1871 CheD, Chemotaxis protein; stimulates methylation of MCP proteins Cell motility and secretion / Signal transduction mechanisms 148269356 Common - putative CheW protein Tpet_0211 122 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 148270010 Common - protein of unknown function DUF362 Tpet_0875 101 COG2006 COG2006, Uncharacterized conserved protein Function unknown 148270622 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B Tpet_1498 214 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 148269372 Common - competence/damage-inducible protein CinA Tpet_0227 213 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 148269737 Common - heavy metal translocating P-type ATPase Tpet_0600 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 148270102 Common - binding-protein-dependent transport systems inner membrane component Tpet_0968 158 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 148270556 Nonpathogen - positive regulator of sigma E, RseC/MucC Tpet_1427 4 COG3086 RseC, Positive regulator of sigma E activity Signal transduction mechanisms 148270076 Common - extracellular solute-binding protein, family 1 Tpet_0942 64 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148270063 Common - cobalt transport protein Tpet_0929 64 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 148270735 Common - ATPase associated with various cellular activities, AAA_3 Tpet_1613 178 COG0714 COG0714, MoxR-like ATPases General function prediction only 148269804 Nonpathogen - hypothetical protein Tpet_0668 1 None None None 148270209 Nonpathogen - protein of unknown function UPF0153 Tpet_1077 2 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 148270162 Common - ATP-NAD/AcoX kinase Tpet_1028 237 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 148269189 Common - pantothenate kinase Tpet_0044 137 COG1521 COG1521, Putative transcriptional regulator, homolog of Bvg accessory factor Transcription 148269612 Common - surface antigen (D15) Tpet_0472 51 COG4775 COG4775, Outer membrane protein/protective antigen OMA87 Cell envelope biogenesis, outer membrane 148270928 Common - ATPase associated with various cellular activities, AAA_5 Tpet_1812 38 COG0714 COG0714, MoxR-like ATPases General function prediction only 148269891 Common - redox-sensing transcriptional repressor Rex Tpet_0756 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 148270784 Common - anti-sigma-factor antagonist Tpet_1663 28 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 148270065 Common - cell envelope-related transcriptional attenuator Tpet_0931 60 COG1316 LytR, Transcriptional regulator Transcription 148270819 Common - outer membrane chaperone Skp (OmpH) Tpet_1698 5 COG2825 HlpA, Outer membrane protein Cell envelope biogenesis, outer membrane 148270721 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_1599 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269749 Common - carbohydrate kinase, FGGY Tpet_0613 159 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148269565 Common - PhoH family protein Tpet_0425 198 COG1875 COG1875, Predicted ATPase related to phosphate starvation-inducible protein PhoH Signal transduction mechanisms 148270638 Nonpathogen - ATPase-like protein Tpet_1514 20 COG0433 COG0433, Predicted ATPase General function prediction only 148270909 Common - Monosaccharide-transporting ATPase Tpet_1793 115 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148269460 Common - ribosomal protein S6 Tpet_0315 126 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 148269303 Common - Radical SAM domain protein Tpet_0158 99 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 148270612 Common - Cupin 2, conserved barrel domain protein Tpet_1488 28 COG0662 {ManC}, Mannose-6-phosphate isomerase Carbohydrate transport and metabolism 148270686 Common - transposase, IS605 OrfB family Tpet_1563 75 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 148269467 Common - extracellular solute-binding protein, family 1 Tpet_0322 109 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148270343 Common prfB peptide chain release factor 2 Tpet_1213 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 148270859 Common - Esterase/lipase-like protein Tpet_1741 25 COG0657 Aes, Esterase/lipase Lipid metabolism 148269508 Common - 3-isopropylmalate dehydrogenase Tpet_0364 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 148270109 Common - beta-lactamase domain protein Tpet_0975 58 COG1237 COG1237, Metal-dependent hydrolases of the beta-lactamase superfamily II General function prediction only 148270682 Common - glycoside hydrolase family 2, TIM barrel Tpet_1559 75 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 148269445 Common - UDP-N-acetylglucosamine 2-epimerase Tpet_0300 152 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 148269202 Common - Peptidoglycan glycosyltransferase Tpet_0057 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 148270036 Common - protein of unknown function DUF190 Tpet_0902 57 COG1993 COG1993, Uncharacterized conserved protein Function unknown 148269996 Nonpathogen - hypothetical protein Tpet_0861 1 None None None 148270148 Common - Ribulose-phosphate 3-epimerase Tpet_1014 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 148269742 Common - oxidoreductase domain protein Tpet_0605 158 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 148269948 Common - iron-containing alcohol dehydrogenase Tpet_0813 173 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 148270461 Common - ribonuclease P protein component Tpet_1331 50 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 148269683 Common - arginine repressor, ArgR Tpet_0546 81 COG1438 ArgR, Arginine repressor Transcription 148270595 Nonpathogen - hypothetical protein Tpet_1468 1 None None None 148269662 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Tpet_0524 154 COG1142 HycB, Fe-S-cluster-containing hydrogenase components 2 Energy production and conversion 148269898 Nonpathogen - hypothetical protein Tpet_0763 4 COG2267 PldB, Lysophospholipase Lipid metabolism 148269478 Common - oxidoreductase domain protein Tpet_0333 195 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 148270826 Nonpathogen - alpha/beta hydrolase fold Tpet_1705 4 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148270528 Common - adenine phosphoribosyltransferase Tpet_1399 193 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 148270609 Common - beta-lactamase domain protein Tpet_1485 125 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148270442 Common secY preprotein translocase subunit SecY Tpet_1312 223 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 148269894 Common - FolC bifunctional protein Tpet_0759 217 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 148269854 Common - hypoxanthine phosphoribosyltransferase Tpet_0718 149 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 148270093 Common - pullulanase, type I Tpet_0959 151 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 148270620 Nonpathogen - prevent-host-death family protein Tpet_1496 5 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 148270033 Common - glycoside hydrolase, family 16 Tpet_0899 49 COG2273 SKN1, Beta-glucanase/Beta-glucan synthetase Carbohydrate transport and metabolism 148269756 Common leuD 3-isopropylmalate dehydratase small subunit Tpet_0620 212 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 148269427 Common - DNA polymerase, beta domain protein region Tpet_0282 9 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 148269388 Common - glyceraldehyde-3-phosphate dehydrogenase, type I Tpet_0243 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 148270914 Nonpathogen - hypothetical protein Tpet_1798 3 None None None 148270778 Common - Rhomboid family protein Tpet_1657 105 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 148269265 Common - ROK family protein Tpet_0120 46 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148270886 Nonpathogen - hypothetical protein Tpet_1770 1 None None None 148269967 Nonpathogen - hypothetical protein Tpet_0832 3 None None None 148270924 Common - Citrate transporter Tpet_1808 72 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 148269346 Common - protein of unknown function DUF6, transmembrane Tpet_0201 56 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 148269778 Common - LamG domain protein jellyroll fold domain protein Tpet_0642 10 None None None 148269999 Common - binding-protein-dependent transport systems inner membrane component Tpet_0864 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269257 Common - hypothetical protein Tpet_0112 4 None None None 148269702 Common - Outer membrane protein-like protein Tpet_0565 12 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148269656 Common - ammonium transporter Tpet_0518 203 COG0004 AmtB, Ammonia permease Inorganic ion transport and metabolism 148269397 Common - flagellar motor switch protein FliM Tpet_0252 103 COG1868 FliM, Flagellar motor switch protein Cell motility and secretion 148270081 Common - glycosidase, PH1107-related Tpet_0947 36 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 148269284 Common - Phosphomethylpyrimidine kinase type-1 Tpet_0139 186 COG1992 COG1992, Uncharacterized conserved protein Function unknown 148269909 Common - protein of unknown function DUF177 Tpet_0774 47 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 148270027 Common - binding-protein-dependent transport systems inner membrane component Tpet_0893 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270007 Nonpathogen - hypothetical protein Tpet_0872 1 None None None 148269218 Common - metal dependent phosphohydrolase Tpet_0073 59 COG1639 COG1639, Predicted signal transduction protein Signal transduction mechanisms 148270872 Common - protein of unknown function DUF1175 Tpet_1755 13 COG3234 COG3234, Uncharacterized protein conserved in bacteria Function unknown 148269240 Common - Zn-ribbon-containing protein Tpet_0095 10 COG5512 COG5512, Zn-ribbon-containing, possibly RNA-binding protein and truncated derivatives General function prediction only 148270021 Common - protein of unknown function DUF265 Tpet_0887 22 COG1618 COG1618, Predicted nucleotide kinase Nucleotide transport and metabolism 148269235 Common - type II secretion system protein E Tpet_0090 209 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 148269539 Common - hypothetical protein Tpet_0397 16 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 148270804 Common - binding-protein-dependent transport systems inner membrane component Tpet_1683 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270852 Nonpathogen - protein of unknown function DUF505 Tpet_1732 7 COG1542 COG1542, Uncharacterized conserved protein Function unknown 148269951 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase Tpet_0816 213 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 148270335 Nonpathogen - hypothetical protein Tpet_1205 3 None None None 148269597 Common - lipoprotein signal peptidase Tpet_0457 189 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148270158 Common - S-layer domain protein Tpet_1024 115 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 148270437 Common rplF 50S ribosomal protein L6 Tpet_1307 246 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 148270831 Common - histidinol-phosphate aminotransferase Tpet_1710 233 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 148269808 Common - glutamyl-tRNA(Gln) amidotransferase, C subunit Tpet_0672 85 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 148270457 Common - small GTP-binding protein Tpet_1327 227 COG0218 COG0218, Predicted GTPase General function prediction only 148270740 Nonpathogen - hypothetical protein Tpet_1618 2 None None None 148270797 Common - glycoside hydrolase, family 4 Tpet_1676 53 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 148270430 Common - ribosomal protein L29 Tpet_1300 70 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 148269546 Nonpathogen - hypothetical protein Tpet_0404 1 None None None 148270790 Common - ExsB family protein Tpet_1669 14 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 148270719 Common - binding-protein-dependent transport systems inner membrane component Tpet_1597 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269192 Common - sodium ion-translocating decarboxylase, beta subunit Tpet_0047 56 COG1883 OadB, Na+-transporting methylmalonyl-CoA/oxaloacetate decarboxylase, beta subunit Energy production and conversion 148270198 Common nusA transcription elongation factor NusA Tpet_1065 229 COG0195 NusA, Transcription elongation factor Transcription 148270499 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit Tpet_1369 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 148269207 Common - protein of unknown function DUF107 Tpet_0062 96 COG1585 COG1585, Membrane protein implicated in regulation of membrane protease activity Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148270321 Common - Radical SAM domain protein Tpet_1191 57 COG1031 COG1031, Uncharacterized Fe-S oxidoreductase Energy production and conversion 148269455 Common - hypothetical protein Tpet_0310 40 COG1738 COG1738, Uncharacterized conserved protein Function unknown 148269365 Common - transcriptional regulator, MarR family Tpet_0220 57 COG1846 MarR, Transcriptional regulators Transcription 148270177 Common - hypothetical protein Tpet_1044 15 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148270452 Common rho transcription termination factor Rho Tpet_1322 219 COG1158 Rho, Transcription termination factor Transcription 148269273 Common - 2-nitropropane dioxygenase, NPD Tpet_0128 144 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 148269420 Common - Cupin 2, conserved barrel domain protein Tpet_0275 137 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 148269884 Common - protein of unknown function DUF89 Tpet_0749 40 COG1578 COG1578, Uncharacterized conserved protein Function unknown 148270860 Common - 2,5-didehydrogluconate reductase Tpet_1742 182 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 148270509 Common - Beta-fructofuranosidase Tpet_1379 54 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 148270490 Common - protein of unknown function DUF1667 Tpet_1360 14 COG3862 COG3862, Uncharacterized protein with conserved CXXC pairs Function unknown 148269496 Common - transcriptional regulator, BadM/Rrf2 family Tpet_0351 170 COG1959 COG1959, Predicted transcriptional regulator Transcription 148269627 Common - binding-protein-dependent transport systems inner membrane component Tpet_0487 203 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269221 Common - heat-inducible transcription repressor HrcA Tpet_0076 151 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 148269335 Common - metal dependent phosphohydrolase Tpet_0190 118 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 148270714 Common - glutamine amidotransferase class-I Tpet_1592 111 COG0518 GuaA, GMP synthase - Glutamine amidotransferase domain Nucleotide transport and metabolism 148269211 Common - protein-export membrane protein SecF Tpet_0066 205 COG0341 SecF, Preprotein translocase subunit SecF Intracellular trafficking and secretion 148269511 Common - 2-isopropylmalate synthase Tpet_0367 216 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 148270406 Common - amidohydrolase Tpet_1276 166 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 148270685 Common - galactokinase Tpet_1562 108 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 148270028 Common - binding-protein-dependent transport systems inner membrane component Tpet_0894 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269812 Common - electron transport complex, RnfABCDGE type, A subunit Tpet_0676 76 COG4657 RnfA, Predicted NADH:ubiquinone oxidoreductase, subunit RnfA Energy production and conversion 148269610 Nonpathogen - hypothetical protein Tpet_0470 1 None None None 148270568 Common - ribosomal protein S15 Tpet_1439 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 148270355 Common - RNA-binding protein (contains KH domain)-like protein Tpet_1225 50 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 148269578 Common - putative CoA-substrate-specific enzyme activase Tpet_0438 65 COG3581 COG3581, Uncharacterized protein conserved in bacteria Function unknown 148269634 Common - oxidoreductase domain protein Tpet_0495 93 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 148270114 Common - ribosomal protein L31 Tpet_0980 129 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 148269822 Nonpathogen - hypothetical protein Tpet_0686 3 None None None 148270772 Nonpathogen - hypothetical protein Tpet_1651 1 None None None 148270681 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_1558 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269932 Common - integral membrane sensor signal transduction histidine kinase Tpet_0797 3 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148270737 Common - Phosphate acetyltransferase Tpet_1615 135 COG0280 Pta, Phosphotransacetylase Energy production and conversion 148270205 Common - acetylornithine and succinylornithine aminotransferase Tpet_1072 237 COG4992 ArgD, Ornithine/acetylornithine aminotransferase Amino acid transport and metabolism 148270673 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_1549 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 148270302 Common - DNA polymerase I Tpet_1172 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 148269617 Common - carbohydrate kinase, FGGY Tpet_0477 181 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148269185 Common - methylated-DNA--protein-cysteine methyltransferase Tpet_0040 220 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 148270318 Common - uridylate kinase Tpet_1188 229 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 148269960 Nonpathogen - hypothetical protein Tpet_0825 1 None None None 148269701 Common - threonine dehydratase Tpet_0564 215 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 148270745 Common - flagellar hook-associated 2 domain protein Tpet_1623 73 COG1345 FliD, Flagellar capping protein Cell motility and secretion 148270445 Common - translation initiation factor IF-1 Tpet_1315 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 148269625 Common - extracellular solute-binding protein, family 5 Tpet_0485 108 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148269961 Common obgE GTPase ObgE Tpet_0826 249 COG0536 Obg, Predicted GTPase General function prediction only 148269246 Nonpathogen - hypothetical protein Tpet_0101 1 None None None 148269878 Common - DNA polymerase III, delta subunit Tpet_0743 14 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 148270160 Common - alanine racemase domain protein Tpet_1026 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 148269733 Common - Tripartite ATP-independent periplasmic transporter, DctQ component Tpet_0596 13 COG3090 DctM, TRAP-type C4-dicarboxylate transport system, small permease component Carbohydrate transport and metabolism 148269642 Common - Xylose isomerase domain protein TIM barrel Tpet_0504 74 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 148269831 Common - Auxin Efflux Carrier Tpet_0695 12 COG0679 COG0679, Predicted permeases General function prediction only 148270313 Common - DegV family protein Tpet_1183 19 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 148269358 Nonpathogen - hypothetical protein Tpet_0213 2 None None None 148270098 Nonpathogen - hypothetical protein Tpet_0964 3 None None None 148269157 Common - Ribonuclease H Tpet_0012 234 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 148269783 Nonpathogen - hypothetical protein Tpet_0647 1 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148270543 Common - FeS assembly protein SufB Tpet_1414 188 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 148269692 Common - Fibronectin-binding A domain protein Tpet_0555 95 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 148269975 Nonpathogen - hypothetical protein Tpet_0840 1 None None None 148270617 Common - MutS2 family protein Tpet_1493 204 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 148270573 Common - hypothetical protein Tpet_1444 40 None None None 148270918 Common - pseudouridine synthase, RluA family Tpet_1802 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 148269418 Nonpathogen - Superoxide reductase Tpet_0273 24 COG2033 COG2033, Desulfoferrodoxin Energy production and conversion 148269183 Common - 1-deoxy-D-xylulose 5-phosphate reductoisomerase Tpet_0038 184 COG0743 Dxr, 1-deoxy-D-xylulose 5-phosphate reductoisomerase Lipid metabolism 148270779 Nonpathogen - hypothetical protein Tpet_1658 11 None None None 148269462 Nonpathogen - hypothetical protein Tpet_0317 1 None None None 148270540 Common - SUF system FeS assembly protein, NifU family Tpet_1411 171 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 148269429 Common - NAD+ synthetase Tpet_0284 215 COG0171 NadE, NAD synthase Coenzyme metabolism 148270046 Common - Ferredoxin-like protein Tpet_0912 26 COG3411 COG3411, Ferredoxin Energy production and conversion 148270067 Common - Uncharacterized protein-like protein Tpet_0933 13 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 148270341 Common - type I phosphodiesterase/nucleotide pyrophosphatase Tpet_1211 32 COG1524 COG1524, Uncharacterized proteins of the AP superfamily General function prediction only 148270694 Common - NUDIX hydrolase Tpet_1572 152 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 148269164 Common - flagellar biosynthesis protein FlhA Tpet_0019 127 COG1298 FlhA, Flagellar biosynthesis pathway, component FlhA Cell motility and secretion / Intracellular trafficking and secretion 148270277 Common - quinolinate synthetase Tpet_1147 196 COG0379 NadA, Quinolinate synthase Coenzyme metabolism 148269599 Common - DNA polymerase III, alpha subunit Tpet_0459 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 148269791 Common - Vitamin B12 dependent methionine synthase, activation region Tpet_0655 11 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 148270644 Common - phosphoribosylaminoimidazole synthetase Tpet_1520 225 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 148270893 Common - putative PAS/PAC sensor protein Tpet_1777 26 COG2461 COG2461, Uncharacterized conserved protein Function unknown 148270201 Common - argininosuccinate lyase Tpet_1068 224 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 148270723 Common - binding-protein-dependent transport systems inner membrane component Tpet_1601 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269200 Common - S-adenosyl-methyltransferase MraW Tpet_0055 216 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 148270743 Nonpathogen - hypothetical protein Tpet_1621 1 None None None 148269660 Common - glutamine amidotransferase, class-II Tpet_0522 145 COG0067 GltB, Glutamate synthase domain 1 Amino acid transport and metabolism 148269422 Common - spermidine synthase Tpet_0277 130 COG0421 SpeE, Spermidine synthase Amino acid transport and metabolism 148270346 Common - hemolysin A Tpet_1216 134 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 148270480 Common - hydroxymethylbutenyl pyrophosphate reductase Tpet_1350 188 COG0761 LytB, Penicillin tolerance protein Lipid metabolism / Cell envelope biogenesis, outer membrane 148270843 Common - ABC transporter related Tpet_1722 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148269209 Common - ribosomal protein L9 Tpet_0064 193 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 148269167 Nonpathogen - type IV pilus assembly PilZ Tpet_0022 7 COG5581 COG5581, Predicted glycosyltransferase Cell envelope biogenesis, outer membrane 148269946 Common - polysaccharide deacetylase Tpet_0811 103 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 148269998 Common - Endo-1,4-beta-xylanase Tpet_0863 37 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 148269844 Common glyQ glycyl-tRNA synthetase subunit alpha Tpet_0708 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 148270373 Common - glycosyl transferase, family 4 Tpet_1243 102 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 148269301 Common - PSP1 domain protein Tpet_0156 57 COG1774 COG1774, Uncharacterized homolog of PSP1 Function unknown 148269789 Nonpathogen - hypothetical protein Tpet_0653 3 None None None 148269353 Common - uracil phosphoribosyltransferase Tpet_0208 164 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 148270245 Common - transposase, IS605 OrfB family Tpet_1115 63 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 148270012 Nonpathogen - hypothetical protein Tpet_0878 3 None None None 148270332 Common - ribosomal protein L35 Tpet_1202 112 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 148270489 Common - CoA-binding domain protein Tpet_1359 122 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 148270767 Common - ornithine carbamoyltransferase Tpet_1646 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 148270566 Common - peptidase M16 domain protein Tpet_1437 200 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 148269523 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, alpha subunit Tpet_0381 148 COG1951 TtdA, Tartrate dehydratase alpha subunit/Fumarate hydratase class I, N-terminal domain Energy production and conversion 148269149 Common - Tetratricopeptide TPR_2 repeat protein Tpet_0004 6 COG1729 COG1729, Uncharacterized protein conserved in bacteria Function unknown 148269838 Common - ABC transporter related Tpet_0702 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 148270589 Common - ABC transporter related Tpet_1460 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148270052 Common - putative DNA helicase Tpet_0918 100 COG1112 COG1112, Superfamily I DNA and RNA helicases and helicase subunits DNA replication, recombination, and repair 148270782 Nonpathogen - protein of unknown function DUF101 Tpet_1661 2 COG1371 COG1371, Uncharacterized conserved protein Function unknown 148269513 Common - dihydroxy-acid dehydratase Tpet_0369 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 148270726 Common - cytochrome c biogenesis protein, transmembrane region Tpet_1604 147 COG0785 CcdA, Cytochrome c biogenesis protein Posttranslational modification, protein turnover, chaperones 148269482 Nonpathogen - thioesterase-like protein Tpet_0337 4 COG5496 COG5496, Predicted thioesterase General function prediction only 148269601 Common - DNA-directed RNA polymerase, beta' subunit Tpet_0461 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 148269376 Nonpathogen - hypothetical protein Tpet_0231 3 COG3190 FliO, Flagellar biogenesis protein Cell motility and secretion 148269667 Common - Glycerol-3-phosphate dehydrogenase (NAD(P)(+)) Tpet_0529 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 148270521 Nonpathogen - hypothetical protein Tpet_1391 1 None None None 148269563 Common - protein of unknown function DUF125, transmembrane Tpet_0423 38 COG1814 COG1814, Uncharacterized membrane protein Function unknown 148270131 Common - MATE efflux family protein Tpet_0997 184 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 148269308 Common - ABC transporter related Tpet_0163 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148269744 Common - Beta-galactosidase Tpet_0607 40 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 148269689 Common - endonuclease III Tpet_0552 240 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 148270019 Common - 6-pyruvoyl tetrahydropterin synthase and hypothetical protein Tpet_0885 136 COG0720 COG0720, 6-pyruvoyl-tetrahydropterin synthase Coenzyme metabolism 148269747 Common - L-fucose isomerase, N-terminal_2 domain protein Tpet_0610 23 COG2407 FucI, L-fucose isomerase and related proteins Carbohydrate transport and metabolism 148270631 Common - phosphate binding protein Tpet_1507 180 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 148269896 Common - protein of unknown function DUF368 Tpet_0761 50 COG2035 COG2035, Predicted membrane protein Function unknown 148269249 Common - transcriptional regulator, TetR family Tpet_0104 93 COG1309 AcrR, Transcriptional regulator Transcription 148270864 Common - regulatory protein, ArsR Tpet_1747 172 COG0640 ArsR, Predicted transcriptional regulators Transcription 148269469 Common - extracellular solute-binding protein, family 3 Tpet_0324 197 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 148270467 Nonpathogen - protein of unknown function DUF464 Tpet_1337 1 COG2868 COG2868, Predicted ribosomal protein Translation, ribosomal structure and biogenesis 148270415 Common - PhoH family protein Tpet_1285 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 148269434 Nonpathogen - hypothetical protein Tpet_0289 4 None None None 148270806 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_1685 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270390 Common - FAD dependent oxidoreductase Tpet_1260 165 COG0644 FixC, Dehydrogenases (flavoproteins) Energy production and conversion 148270270 Common - translation elongation factor G Tpet_1140 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 148269489 Common - S-adenosylmethionine--tRNA-ribosyltransferase-isomerase Tpet_0344 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 148269582 Common - tyrosyl-tRNA synthetase Tpet_0442 243 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148270593 Common - ABC transporter related Tpet_1466 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148269332 Common - metallophosphoesterase Tpet_0187 97 COG1409 Icc, Predicted phosphohydrolases General function prediction only 148270380 Common - flagellar basal-body rod protein FlgG Tpet_1250 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 148270128 Common - aspartate aminotransferase Tpet_0994 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 148269722 Common - 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductase-like protein Tpet_0585 54 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 148269866 Common - ABC transporter related Tpet_0730 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 148270287 Nonpathogen - hypothetical protein Tpet_1157 3 None None None 148270378 Common - cell shape determining protein, MreB/Mrl family Tpet_1248 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 148270387 Common - Polyprenyl synthetase Tpet_1257 241 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 148269606 Common - ribosomal protein L11 Tpet_0466 249 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 148270421 Common - ribosomal protein S10 Tpet_1291 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 148269370 Common - ABC transporter related Tpet_0225 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 148270624 Nonpathogen - hypothetical protein Tpet_1500 1 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 148269501 Common - hypothetical protein Tpet_0356 13 None None None 148270901 Common - DNA mismatch repair protein MutS domain protein Tpet_1785 82 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 148270707 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Tpet_1585 111 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 148269561 Nonpathogen - hypothetical protein Tpet_0421 1 None None None 148270074 Common - metal dependent phosphohydrolase Tpet_0940 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 148270225 Common - CRISPR-associated RAMP protein, Csm3 family Tpet_1095 33 COG1337 COG1337, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 148270168 Nonpathogen - protein of unknown function DUF430 Tpet_1034 2 COG2380 COG2380, Uncharacterized protein conserved in bacteria Function unknown 148269775 Common - glycoside hydrolase, family 43 Tpet_0639 27 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 148270580 Nonpathogen - helix-turn-helix domain protein Tpet_1451 6 COG1709 COG1709, Predicted transcriptional regulator Transcription 148269714 Common - 3-deoxy-7-phosphoheptulonate synthase Tpet_0577 186 COG2876 AroA, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 148270326 Common - purine nucleoside phosphorylase Tpet_1196 141 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 148269175 Common - Stage V sporulation protein S Tpet_0030 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 148270751 Nonpathogen - hypothetical protein Tpet_1629 1 None None None 148270207 Common - regulatory protein, ArsR Tpet_1075 94 COG0640 ArsR, Predicted transcriptional regulators Transcription 148269992 Common - PfkB domain protein Tpet_0857 116 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148270554 Common - protein of unknown function DUF82 Tpet_1425 36 COG1656 COG1656, Uncharacterized conserved protein Function unknown 148270392 Common - Electron transfer flavoprotein, alpha/beta-subunit-like protein Tpet_1262 152 COG2086 FixA, Electron transfer flavoprotein, beta subunit Energy production and conversion 148269781 Common - binding-protein-dependent transport systems inner membrane component Tpet_0645 159 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148270001 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_0866 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270232 Common - valyl-tRNA synthetase Tpet_1102 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148269227 Common - protein of unknown function DUF21 Tpet_0082 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 148270715 Nonpathogen - hypothetical protein Tpet_1593 1 None None None 148269595 Nonpathogen - hypothetical protein Tpet_0455 1 None None None 148269870 Common - transport system permease protein Tpet_0734 196 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 148270679 Common - periplasmic binding protein/LacI transcriptional regulator Tpet_1556 131 COG1609 PurR, Transcriptional regulators Transcription 148269640 Common - binding-protein-dependent transport systems inner membrane component Tpet_0502 140 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148270862 Common - AraC-type transcriptional regulator domain protein Tpet_1744 139 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 148269671 Common - HhH-GPD family protein Tpet_0533 170 COG2231 COG2231, Uncharacterized protein related to Endonuclease III DNA replication, recombination, and repair 148269154 Common - methyl-accepting chemotaxis sensory transducer Tpet_0009 153 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148269880 Common - hypothetical protein Tpet_0745 7 None None None 148269986 Common - binding-protein-dependent transport systems inner membrane component Tpet_0851 215 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269194 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit alpha Tpet_0049 110 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 148269945 Common - periplasmic binding protein/LacI transcriptional regulator Tpet_0810 106 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148269623 Common - glycoside hydrolase, family 28 Tpet_0483 26 COG5434 PGU1, Endopygalactorunase Cell envelope biogenesis, outer membrane 148269882 Common - primosomal protein N' Tpet_0747 227 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 148269367 Common - biotin/lipoate A/B protein ligase Tpet_0222 51 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 148269694 Nonpathogen - hypothetical protein Tpet_0557 1 None None None 148270257 Common - methyltransferase small Tpet_1127 149 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 148270190 Common - exodeoxyribonuclease VII, small subunit Tpet_1057 103 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 148270133 Common - sulfatase Tpet_0999 65 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 148269282 Common - hypothetical protein Tpet_0137 110 COG1738 COG1738, Uncharacterized conserved protein Function unknown 148269963 Common - putative TIM-barrel protein, nifR3 family Tpet_0828 207 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 148270260 Common - peptide deformylase Tpet_1130 214 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 148270350 Common - signal peptidase I Tpet_1220 185 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 148270749 Nonpathogen - hypothetical protein Tpet_1627 4 None None None 148269686 Common - major facilitator superfamily MFS_1 Tpet_0549 51 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 148269858 Common - ABC-type nitrate/sulfonate/bicarbonate transport systems periplasmic components-like protein Tpet_0722 32 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 148270691 Common - diguanylate cyclase with PAS/PAC sensor Tpet_1569 190 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 148269823 Common - UDP-N-acetylmuramyl-tripeptide synthetase Tpet_0687 210 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 148269274 Common - BioY protein Tpet_0129 114 COG1268 BioY, Uncharacterized conserved protein General function prediction only 148269343 Common - protein of unknown function DUF208 Tpet_0198 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 148269752 Common - PfkB domain protein Tpet_0616 189 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148269490 Common - apolipoprotein N-acyltransferase Tpet_0345 158 COG0815 Lnt, Apolipoprotein N-acyltransferase Cell envelope biogenesis, outer membrane 148269767 Common - Alpha-N-arabinofuranosidase Tpet_0631 32 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 148269815 Common - electron transport complex, RnfABCDGE type, D subunit Tpet_0679 76 COG4658 RnfD, Predicted NADH:ubiquinone oxidoreductase, subunit RnfD Energy production and conversion 148270267 Common - PAS/PAC sensor signal transduction histidine kinase Tpet_1137 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 148270866 Common - redox-active disulfide protein 2 Tpet_1749 67 None None None 148270630 Common - AAA ATPase Tpet_1506 27 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 148270008 Common - ferrous iron transport protein B Tpet_0873 214 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 148270926 Common - restriction endonuclease Tpet_1810 4 COG1787 COG1787, Predicted endonuclease distantly related to archaeal Holliday junction resolvase and Mrr-like restriction enzymes Defense mechanisms 148269704 Common - efflux transporter, RND family, MFP subunit Tpet_0567 89 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 148270399 Common - aspartate-semialdehyde dehydrogenase Tpet_1269 235 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 148269316 Common - glycosyl transferase, family 2 Tpet_0171 68 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148269498 Common - sugar fermentation stimulation protein Tpet_0353 106 COG1489 SfsA, DNA-binding protein, stimulates sugar fermentation General function prediction only 148269788 Common - pyruvate phosphate dikinase Tpet_0652 235 COG0574 PpsA, Phosphoenolpyruvate synthase/pyruvate phosphate dikinase Carbohydrate transport and metabolism 148270295 Common - peptidyl-tRNA hydrolase Tpet_1165 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 148270504 Common - Nucleotidyl transferase Tpet_1374 78 COG1213 COG1213, Predicted sugar nucleotidyltransferases Cell envelope biogenesis, outer membrane 148269929 Common - major facilitator superfamily MFS_1 Tpet_0794 78 COG2270 COG2270, Permeases of the major facilitator superfamily General function prediction only 148270362 Common - Formiminotransferase-cyclodeaminase Tpet_1232 38 COG3404 COG3404, Methenyl tetrahydrofolate cyclohydrolase Amino acid transport and metabolism 148269217 Common - ribosome-binding factor A Tpet_0072 139 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 148269915 Common - putative metalloendopeptidase, glycoprotease family Tpet_0780 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 148270549 Common - peptide chain release factor 1 Tpet_1420 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 148269649 Common - peptidase M23B Tpet_0511 193 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 148270845 Nonpathogen - integral membrane protein-like protein Tpet_1724 3 COG5652 COG5652, Predicted integral membrane protein Function unknown 148270359 Common - MscS Mechanosensitive ion channel Tpet_1229 200 COG3264 COG3264, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 148270181 Common - pyruvate ferredoxin/flavodoxin oxidoreductase Tpet_1048 50 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 148270805 Common - binding-protein-dependent transport systems inner membrane component Tpet_1684 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269262 Common - binding-protein-dependent transport systems inner membrane component Tpet_0117 176 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148270023 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Tpet_0889 53 COG2768 COG2768, Uncharacterized Fe-S center protein General function prediction only 148269243 Common - CBS domain containing protein Tpet_0098 111 COG3448 COG3448, CBS-domain-containing membrane protein Signal transduction mechanisms 148269533 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_0391 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270604 Common - ABC transporter related Tpet_1479 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148270089 Common - binding-protein-dependent transport systems inner membrane component Tpet_0955 172 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148270115 Common - RNA binding S1 domain protein Tpet_0981 229 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 148270837 Common - UDP-N-acetylglucosamine 2-epimerase Tpet_1716 154 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 148269514 Common - ketol-acid reductoisomerase Tpet_0370 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 148269556 Common - chaperonin Cpn10 Tpet_0416 208 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 148269289 Common - Linocin_M18 bacteriocin protein Tpet_0144 21 COG1659 COG1659, Uncharacterized protein, linocin/CFP29 homolog Function unknown 148269297 Common - transposase, IS605 OrfB family Tpet_0152 60 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 148270078 Common - hypothetical protein Tpet_0944 7 COG1331 COG1331, Highly conserved protein containing a thioredoxin domain Posttranslational modification, protein turnover, chaperones 148270459 Common - Indigoidine synthase A family protein Tpet_1329 49 COG2313 IndA, Uncharacterized enzyme involved in pigment biosynthesis Secondary metabolites biosynthesis, transport, and catabolism 148270447 Common rpsM 30S ribosomal protein S13 Tpet_1317 248 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 148269911 Common - fatty acid/phospholipid synthesis protein Tpet_0776 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 148270606 Nonpathogen - hypothetical protein Tpet_1481 1 None None None 148270874 Common - alpha-2-macroglobulin domain protein Tpet_1757 70 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 148270518 Nonpathogen - hypothetical protein Tpet_1388 4 None None None 148269635 Common - Auxin Efflux Carrier Tpet_0496 155 COG0679 COG0679, Predicted permeases General function prediction only 148270120 Common - hypothetical protein Tpet_0986 33 COG2052 COG2052, Uncharacterized protein conserved in bacteria Function unknown 148270013 Nonpathogen - hypothetical protein Tpet_0879 1 None None None 148269248 Common - Radical SAM domain protein Tpet_0103 102 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 148270427 Common - ribosomal protein L22 Tpet_1297 221 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 148270436 Common - ribosomal protein S8 Tpet_1306 249 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 148270075 Common - Alanine racemase Tpet_0941 126 COG1609 PurR, Transcriptional regulators Transcription 148270594 Common - Radical SAM domain protein Tpet_1467 53 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 148270154 Common - 3-oxoacyl-(acyl-carrier-protein) reductase Tpet_1020 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148270559 Common - hypothetical protein Tpet_1430 8 None None None 148269547 Common - conserved hypothetical radical SAM protein Tpet_0407 83 COG1242 COG1242, Predicted Fe-S oxidoreductase General function prediction only 148269958 Nonpathogen - hypothetical protein Tpet_0823 4 None None None 148270731 Common - inner-membrane translocator Tpet_1609 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 148270210 Common - diguanylate cyclase Tpet_1078 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 148269484 Common - tRNA(Ile)-lysidine synthetase Tpet_0339 230 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 148269836 Common - biotin--acetyl-CoA-carboxylase ligase Tpet_0700 213 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 148270535 Common - binding-protein-dependent transport systems inner membrane component Tpet_1406 208 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 148270744 Common - flagellar protein FlaG protein Tpet_1622 31 COG1334 FlaG, Uncharacterized flagellar protein FlaG Cell motility and secretion 148269773 Common - glycoside hydrolase, family 43 Tpet_0637 33 COG3507 XynB, Beta-xylosidase Carbohydrate transport and metabolism 148269893 Common - phosphopentomutase Tpet_0758 71 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 148269383 Common - holo-acyl-carrier-protein synthase Tpet_0238 100 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 148269543 Common - tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase Tpet_0401 213 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 148270217 Nonpathogen - hypothetical protein Tpet_1087 4 None None None 148270920 Common - Methyltransferase type 12 Tpet_1804 140 COG2227 UbiG, 2-polyprenyl-3-methyl-5-hydroxy-6-metoxy-1,4-benzoquinol methylase Coenzyme metabolism 148269195 Common - Phosphopyruvate hydratase Tpet_0050 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 148270073 Common - regulatory protein RecX Tpet_0939 40 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 148269251 Common - phenylalanyl-tRNA synthetase, alpha subunit Tpet_0106 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 148270642 Common - NAD+ synthetase Tpet_1518 237 COG0171 NadE, NAD synthase Coenzyme metabolism 148269311 Common rpsB 30S ribosomal protein S2 Tpet_0166 247 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 148270551 Common - isoleucyl-tRNA synthetase Tpet_1422 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148270404 Common - aspartate kinase Tpet_1274 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 148270106 Common - transposase IS200-family protein Tpet_0972 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 148270919 Common - aspartate alpha-decarboxylase Tpet_1803 130 COG0853 PanD, Aspartate 1-decarboxylase Coenzyme metabolism 148270122 Common - Cysteine desulfurase Tpet_0988 238 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 148270626 Common - biotin synthase Tpet_1502 183 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 148269868 Common - Stage V sporulation protein S Tpet_0732 24 COG2359 SpoVS, Uncharacterized protein conserved in bacteria Function unknown 148269560 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_0420 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269453 Common - UDP-N-acetylglucosamine 2-epimerase Tpet_0308 151 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 148270041 Common - pyruvate ferredoxin/flavodoxin oxidoreductase, delta subunit Tpet_0907 79 COG1144 COG1144, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, delta subunit Energy production and conversion 148270169 Common - ribonuclease III Tpet_1035 38 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 148270289 Common - protein of unknown function UPF0079 Tpet_1159 209 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 148270705 Common - putative oxygen-independent coproporphyrinogen III oxidase Tpet_1583 210 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 148270014 Common - ABC transporter related Tpet_0880 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148269797 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA Tpet_0661 191 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 148270789 Common - phosphodiesterase, MJ0936 family Tpet_1668 47 COG0622 COG0622, Predicted phosphoesterase General function prediction only 148270308 Common - ATP synthase F1, delta subunit Tpet_1178 76 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 148270165 Common - replicative DNA helicase Tpet_1031 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 148270204 Common - acetylglutamate kinase Tpet_1071 220 COG0548 ArgB, Acetylglutamate kinase Amino acid transport and metabolism 148270582 Common - ABC transporter related Tpet_1453 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148270855 Nonpathogen - hypothetical protein Tpet_1736 1 None None None 148270223 Nonpathogen - CRISPR-associated RAMP protein, Csm5 family Tpet_1093 8 COG1332 COG1332, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 148269666 Common - glycosyl transferase, group 1 Tpet_0528 35 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148269895 Common - Holliday junction DNA helicase RuvA Tpet_0760 210 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 148269177 Common - glycogen/starch synthase, ADP-glucose type Tpet_0032 131 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 148270780 Common - methionyl-tRNA synthetase Tpet_1659 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148270575 Nonpathogen - hypothetical protein Tpet_1446 1 None None None 148270814 Common - ferredoxin-dependent glutamate synthase Tpet_1693 40 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 148270562 Common - alpha/beta hydrolase fold Tpet_1433 143 COG2267 PldB, Lysophospholipase Lipid metabolism 148270592 Common - ABC transporter related Tpet_1465 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148269385 Common - GatB/Yqey domain protein Tpet_0240 147 COG1610 COG1610, Uncharacterized conserved protein Function unknown 148269647 Common - ROK family protein Tpet_0509 156 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148269861 Common - DNA repair protein RadA Tpet_0725 204 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 148269607 Common - NusG antitermination factor Tpet_0467 214 COG0250 NusG, Transcription antiterminator Transcription 148269441 Common - sugar transferase Tpet_0296 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 148270655 Common - acid phosphatase/vanadium-dependent haloperoxidase related Tpet_1531 13 COG1963 COG1963, Uncharacterized protein conserved in bacteria Function unknown 148269687 Common - methyl-accepting chemotaxis sensory transducer Tpet_0550 152 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148270634 Common - phosphate ABC transporter, ATPase subunit Tpet_1510 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 148270492 Common - FAD dependent oxidoreductase Tpet_1362 157 COG0579 COG0579, Predicted dehydrogenase General function prediction only 148270069 Common - MiaB-like tRNA modifying enzyme YliG Tpet_0935 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 148270910 Common - Monosaccharide-transporting ATPase Tpet_1794 139 COG1879 RbsB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148269569 Nonpathogen - hypothetical protein Tpet_0429 3 None None None 148269924 Common - Radical SAM domain protein Tpet_0789 88 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 148269464 Common - PHP C-terminal domain protein Tpet_0319 8 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 148269728 Common - DNA methylase N-4/N-6 domain protein Tpet_0591 140 COG0863 COG0863, DNA modification methylase DNA replication, recombination, and repair 148269329 Nonpathogen - hypothetical protein Tpet_0184 1 None None None 148269466 Common - binding-protein-dependent transport systems inner membrane component Tpet_0321 149 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148270143 Common - protein of unknown function UPF0029 Tpet_1009 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 148269337 Nonpathogen - Uncharacterized protein-like protein Tpet_0192 7 COG2908 COG2908, Uncharacterized protein conserved in bacteria Function unknown 148269934 Common - ABC-3 protein Tpet_0799 174 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 148269306 Common - alpha amylase, catalytic region Tpet_0161 49 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 148269757 Common - 3-isopropylmalate dehydratase large subunit Tpet_0621 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 148270032 Common - glycoside hydrolase, family 3 domain protein Tpet_0898 126 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 148269264 Common - glycoside hydrolase, family 3 domain protein Tpet_0119 182 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 148270692 Common - aldo/keto reductase Tpet_1570 197 COG1453 COG1453, Predicted oxidoreductases of the aldo/keto reductase family General function prediction only 148269391 Common - Lytic transglycosylase, catalytic Tpet_0246 29 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 148269855 Common - ATP-dependent DNA helicase RecG Tpet_0719 238 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 148269720 Common - Dipeptidyl aminopeptidase/acylaminoacyl-peptidase-like protein Tpet_0583 36 COG1506 DAP2, Dipeptidyl aminopeptidases/acylaminoacyl-peptidases Amino acid transport and metabolism 148269682 Common - acriflavin resistance protein Tpet_0545 177 COG0841 AcrB, Cation/multidrug efflux pump Defense mechanisms 148270389 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Tpet_1259 86 COG2440 FixX, Ferredoxin-like protein Energy production and conversion 148270188 Common - Methenyltetrahydrofolate cyclohydrolase Tpet_1055 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 148269407 Nonpathogen - hypothetical protein Tpet_0262 9 None None None 148269426 Nonpathogen - hypothetical protein Tpet_0281 4 None None None 148270337 Common - Hydroxypyruvate reductase Tpet_1207 86 COG2379 GckA, Putative glycerate kinase Carbohydrate transport and metabolism 148270239 Nonpathogen - hypothetical protein Tpet_1109 2 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 148270567 Common - polynucleotide phosphorylase/polyadenylase Tpet_1438 236 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 148270908 Common - ABC transporter related Tpet_1792 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148270884 Nonpathogen - hypothetical protein Tpet_1768 5 None None None 148269846 Common - glycine dehydrogenase subunit 2 Tpet_0710 174 COG1003 GcvP, Glycine cleavage system protein P (pyridoxal-binding), C-terminal domain Amino acid transport and metabolism 148270250 Nonpathogen - hypothetical protein Tpet_1120 1 None None None 148270055 Common - phosphodiesterase, MJ0936 family Tpet_0921 95 COG0622 COG0622, Predicted phosphoesterase General function prediction only 148270171 Common - HAD-superfamily hydrolase, subfamily IIA Tpet_1037 117 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 148269760 Common - ABC transporter, transmembrane region Tpet_0624 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148269503 Common - Methyltransferase type 11 Tpet_0358 229 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 148270662 Common - glycoside hydrolase, family 38 Tpet_1538 40 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 148270003 Common - extracellular solute-binding protein, family 5 Tpet_0868 179 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148270485 Common - Uncharacterized protein-like protein Tpet_1355 19 COG3330 COG3330, Uncharacterized protein conserved in bacteria Function unknown 148269210 Common - glucose-1-phosphate thymidyltransferase Tpet_0065 238 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 148269786 Common - acetate kinase Tpet_0650 162 COG0282 ackA, Acetate kinase Energy production and conversion 148269798 Common - DNA polymerase III, beta subunit Tpet_0662 216 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 148269225 Common - GTP-binding protein Era Tpet_0080 237 COG1159 Era, GTPase General function prediction only 148269576 Common - NMT1/THI5 like protein Tpet_0436 108 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 148270248 Nonpathogen - hypothetical protein Tpet_1118 3 COG2245 COG2245, Predicted membrane protein Function unknown 148270195 Common - cofactor-independent phosphoglycerate mutase Tpet_1062 51 COG3635 COG3635, Predicted phosphoglycerate mutase, AP superfamily Carbohydrate transport and metabolism 148270544 Common - FeS assembly ATPase SufC Tpet_1415 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 148269416 Common - protein of unknown function DUF62 Tpet_0271 74 COG1912 COG1912, Uncharacterized conserved protein Function unknown 148270903 Common - protein of unknown function DUF477 Tpet_1787 88 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 148270825 Common - septum site-determining protein MinC Tpet_1704 89 COG0850 MinC, Septum formation inhibitor Cell division and chromosome partitioning 148269349 Nonpathogen - hypothetical protein Tpet_0204 3 None None None 148270570 Nonpathogen - hypothetical protein Tpet_1441 2 None None None 148270895 Common - diguanylate cyclase Tpet_1779 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 148270923 Nonpathogen - putative signal-transduction protein with CBS domains Tpet_1807 24 COG2905 COG2905, Predicted signal-transduction protein containing cAMP-binding and CBS domains Signal transduction mechanisms 148269374 Common - putative CheW protein Tpet_0229 125 COG0835 CheW, Chemotaxis signal transduction protein Cell motility and secretion / Signal transduction mechanisms 148270648 Common - amidophosphoribosyltransferase Tpet_1524 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 148270155 Common - Threonyl/alanyl tRNA synthetase, SAD Tpet_1021 209 COG2872 COG2872, Predicted metal-dependent hydrolases related to alanyl-tRNA synthetase HxxxH domain General function prediction only 148270275 Common - protein of unknown function DUF327 Tpet_1145 6 COG1728 COG1728, Uncharacterized protein conserved in bacteria Function unknown 148269318 Nonpathogen - hypothetical protein Tpet_0173 1 None None None 148270515 Common - undecaprenyl diphosphate synthase Tpet_1385 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 148269361 Common - protein of unknown function DUF1239 Tpet_0216 6 COG1452 Imp, Organic solvent tolerance protein OstA Cell envelope biogenesis, outer membrane 148270636 Common - two component transcriptional regulator, winged helix family Tpet_1512 221 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148269437 Nonpathogen - hypothetical protein Tpet_0292 3 None None None 148269290 Nonpathogen - hypothetical protein Tpet_0145 1 None None None 148269492 Common - protease Do Tpet_0347 223 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 148270419 Common - translation elongation factor G Tpet_1289 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 148269314 Common - transferase hexapeptide repeat containing protein Tpet_0169 234 COG1044 LpxD, UDP-3-O- 3-hydroxymyristoyl 148270667 Common - glycosidase, PH1107-related Tpet_1543 30 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 148270240 Common - Riboflavin synthase Tpet_1110 221 COG0054 RibH, Riboflavin synthase beta-chain Coenzyme metabolism 148270688 Common - protein of unknown function UPF0118 Tpet_1566 118 COG0628 PerM, Predicted permease General function prediction only 148270463 Common - 60 kDa inner membrane insertion protein Tpet_1333 213 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 148270506 Common - ABC transporter related Tpet_1376 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 148270293 Common - ribose-phosphate pyrophosphokinase Tpet_1163 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 148269826 Common - UDP-N-acetylmuramoylalanine--D-glutamate ligase Tpet_0690 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 148269927 Common - isochorismatase hydrolase Tpet_0792 122 COG1535 EntB, Isochorismate hydrolase Secondary metabolites biosynthesis, transport, and catabolism 148269764 Common - carbohydrate kinase, FGGY Tpet_0628 183 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148269345 Common - (p)ppGpp synthetase I, SpoT/RelA Tpet_0200 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 148269908 Common - protein of unknown function DUF1121 Tpet_0773 20 COG0427 ACH1, Acetyl-CoA hydrolase Energy production and conversion 148269904 Common - flavin reductase domain protein, FMN-binding Tpet_0769 128 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 148270677 Common - binding-protein-dependent transport systems inner membrane component Tpet_1554 177 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 148270753 Common - protein of unknown function DUF861, cupin_3 Tpet_1631 26 COG3450 COG3450, Predicted enzyme of the cupin superfamily General function prediction only 148269979 Common - periplasmic binding protein Tpet_0844 166 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 148270307 Common - ATP synthase F0, B subunit Tpet_1177 91 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 148270470 Common rplM 50S ribosomal protein L13 Tpet_1340 234 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 148269299 Common - ribosomal protein L7Ae/L30e/S12e/Gadd45 Tpet_0154 13 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 148269152 Common - iron-containing alcohol dehydrogenase Tpet_0007 174 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 148269173 Nonpathogen - hypothetical protein Tpet_0028 2 None None None 148270717 Common - glucose-6-phosphate 1-dehydrogenase Tpet_1595 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 148270742 Nonpathogen - hypothetical protein Tpet_1620 1 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 148270602 Common - ABC-2 type transporter Tpet_1477 48 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 148269872 Common - protein of unknown function UPF0066 Tpet_0736 99 COG1720 COG1720, Uncharacterized conserved protein Function unknown 148269276 Common - 2-phosphosulfolactate phosphatase Tpet_0131 49 COG2045 COG2045, Phosphosulfolactate phosphohydrolase and related enzymes Coenzyme metabolism / General function prediction only 148269734 Common - TRAP dicarboxylate transporter, DctP subunit Tpet_0597 105 COG1638 DctP, TRAP-type C4-dicarboxylate transport system, periplasmic component Carbohydrate transport and metabolism 148270479 Common - RNA binding S1 domain protein Tpet_1349 214 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 148270583 Common - ABC transporter related Tpet_1454 249 COG4555 NatA, ABC-type Na+ transport system, ATPase component Energy production and conversion / Inorganic ion transport and metabolism 148270704 Nonpathogen - hypothetical protein Tpet_1582 1 None None None 148270730 Common - inner-membrane translocator Tpet_1608 151 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 148269988 Common - extracellular solute-binding protein, family 5 Tpet_0853 151 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148270212 Common - CRISPR-associated protein Cas1 Tpet_1082 96 COG1518 COG1518, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 148269943 Common - xylulokinase Tpet_0808 185 COG1070 XylB, Sugar (pentulose and hexulose) kinases Carbohydrate transport and metabolism 148269516 Common - acetolactate synthase, large subunit, biosynthetic type Tpet_0372 223 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 148270811 Common - Uncharacterized protein-like protein Tpet_1690 17 COG4289 COG4289, Uncharacterized protein conserved in bacteria Function unknown 148269978 Common - flagellar assembly protein FliW Tpet_0843 36 COG1699 COG1699, Uncharacterized protein conserved in bacteria Function unknown 148270476 Nonpathogen - Tetratricopeptide TPR_2 repeat protein Tpet_1346 4 None None None 148269637 Common - Xylose isomerase domain protein TIM barrel Tpet_0499 40 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 148270670 Common - binding-protein-dependent transport systems inner membrane component Tpet_1546 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270323 Nonpathogen - hypothetical protein Tpet_1193 1 None None None 148270761 Common - NADH-ubiquinone oxidoreductase, chain 4L Tpet_1639 19 COG1006 MnhC, Multisubunit Na+/H+ antiporter, MnhC subunit Inorganic ion transport and metabolism 148269718 Nonpathogen - hypothetical protein Tpet_0581 1 None None None 148269181 Common - 1-hydroxy-2-methyl-2-(E)-butenyl 4-diphosphate synthase Tpet_0036 188 COG0821 GcpE, Enzyme involved in the deoxyxylulose pathway of isoprenoid biosynthesis Lipid metabolism 148269972 Common - protein of unknown function DUF52 Tpet_0837 67 COG1355 COG1355, Predicted dioxygenase General function prediction only 148269186 Common - glycosyl transferase, family 51 Tpet_0041 201 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 148269197 Nonpathogen - hypothetical protein Tpet_0052 1 None None None 148269922 Common - tryptophan synthase subunit beta Tpet_0787 229 COG0133 TrpB, Tryptophan synthase beta chain Amino acid transport and metabolism 148269684 Common - hypothetical protein Tpet_0547 92 COG0467 RAD55, RecA-superfamily ATPases implicated in signal transduction Signal transduction mechanisms 148270316 Common - ribonuclease, Rne/Rng family Tpet_1186 185 COG1530 CafA, Ribonucleases G and E Translation, ribosomal structure and biogenesis 148269803 Common - metal dependent phosphohydrolase Tpet_0667 47 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 148270733 Nonpathogen - hypothetical protein Tpet_1611 1 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 148269850 Nonpathogen - hypothetical protein Tpet_0714 1 None None None 148270152 Common - protein of unknown function DUF6, transmembrane Tpet_1018 97 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 148270085 Common - glycosyltransferase 36 Tpet_0951 46 COG3459 COG3459, Cellobiose phosphorylase Carbohydrate transport and metabolism 148269269 Common - histidinol phosphate phosphatase HisJ family Tpet_0124 23 COG1387 HIS2, Histidinol phosphatase and related hydrolases of the PHP family Amino acid transport and metabolism / General function prediction only 148269956 Common - ABC transporter related Tpet_0821 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 148270773 Nonpathogen - hypothetical protein Tpet_1652 1 None None None 148269471 Common - ABC transporter related Tpet_0326 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 148270557 Common - DRTGG domain protein Tpet_1428 8 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 148270117 Common - phosphopantothenoylcysteine decarboxylase/phosphopantothenate--cysteine ligase Tpet_0983 235 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 148270082 Common - glycoside hydrolase, family 38 Tpet_0948 52 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 148270071 Common - 2'-5' RNA ligase Tpet_0937 127 COG1514 LigT, 2'-5' RNA ligase Translation, ribosomal structure and biogenesis 148269233 Common - cell cycle protein Tpet_0088 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 148269253 Common - uracil-xanthine permease Tpet_0108 122 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 148270094 Common - glycoside hydrolase, family 13 domain protein Tpet_0960 18 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 148269541 Common hslU ATP-dependent protease ATP-binding subunit Tpet_0399 209 COG1220 HslU, ATP-dependent protease HslVU (ClpYQ), ATPase subunit Posttranslational modification, protein turnover, chaperones 148270050 Common - transglutaminase domain protein Tpet_0916 21 COG1305 COG1305, Transglutaminase-like enzymes, putative cysteine proteases Amino acid transport and metabolism 148269535 Common - methionyl-tRNA formyltransferase Tpet_0393 228 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 148269713 Common - Prephenate dehydrogenase Tpet_0576 147 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 148270364 Common - metal dependent phosphohydrolase Tpet_1234 32 COG2316 COG2316, Predicted hydrolase (HD superfamily) General function prediction only 148270147 Common - ribosome small subunit-dependent GTPase A Tpet_1013 164 COG1162 COG1162, Predicted GTPases General function prediction only 148269913 Common - iojap-like protein Tpet_0778 178 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 148270024 Common - phospholipase/Carboxylesterase Tpet_0890 50 COG4099 COG4099, Predicted peptidase General function prediction only 148269558 Common - binding-protein-dependent transport systems inner membrane component Tpet_0418 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270434 Common rplE 50S ribosomal protein L5 Tpet_1304 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 148269653 Common - 2-oxoglutarate ferredoxin oxidoreductase subunit beta Tpet_0515 113 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 148269528 Nonpathogen - hypothetical protein Tpet_0386 4 None None None 148270835 Common - imidazoleglycerol phosphate synthase, cyclase subunit Tpet_1714 215 COG0107 HisF, Imidazoleglycerol-phosphate synthase Amino acid transport and metabolism 148269771 Common - binding-protein-dependent transport systems inner membrane component Tpet_0635 143 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148269917 Common - response regulator receiver modulated diguanylate cyclase Tpet_0782 184 COG3706 PleD, Response regulator containing a CheY-like receiver domain and a GGDEF domain Signal transduction mechanisms 148270542 Common - FeS assembly protein SufD Tpet_1413 138 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 148270787 Common - protein of unknown function DUF501 Tpet_1666 27 COG1507 COG1507, Uncharacterized conserved protein Function unknown 148270832 Common - Imidazoleglycerol-phosphate dehydratase Tpet_1711 213 COG0131 HisB, Imidazoleglycerol-phosphate dehydratase Amino acid transport and metabolism 148269280 Common - transposase, putative Tpet_0135 62 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 148269373 Common - CheA signal transduction histidine kinase Tpet_0228 161 COG0643 CheA, Chemotaxis protein histidine kinase and related kinases Cell motility and secretion / Signal transduction mechanisms 148270883 Common - ATPase Tpet_1767 34 COG1672 COG1672, Predicted ATPase (AAA+ superfamily) General function prediction only 148270412 Common - uncharacterised conserved protein UCP033563 Tpet_1282 47 COG4198 COG4198, Uncharacterized conserved protein Function unknown 148269260 Common - Glutamine--fructose-6-phosphate transaminase (isomerizing) Tpet_0115 233 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 148269473 Nonpathogen - hypothetical protein Tpet_0328 1 None None None 148270794 Common - L-rhamnose isomerase Tpet_1673 38 COG4952 COG4952, Predicted sugar isomerase Cell envelope biogenesis, outer membrane 148270802 Common - binding-protein-dependent transport systems inner membrane component Tpet_1681 152 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148269554 Common - recombination factor protein RarA/unknown domain fusion protein Tpet_0414 246 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 148270930 Nonpathogen - hypothetical protein Tpet_1814 4 None None None 148270193 Common - Dak phosphatase Tpet_1060 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 148270876 Common - protein of unknown function DUF395, YeeE/YedE Tpet_1759 15 COG2391 COG2391, Predicted transporter component General function prediction only 148269677 Common - ABC transporter related Tpet_0540 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148269238 Nonpathogen - hypothetical protein Tpet_0093 1 None None None 148270615 Common - ATPase, BadF/BadG/BcrA/BcrD type Tpet_1491 44 COG2971 COG2971, Predicted N-acetylglucosamine kinase Carbohydrate transport and metabolism 148269324 Nonpathogen - hypothetical protein Tpet_0179 2 None None None 148270441 Common - ribosomal protein L15 Tpet_1311 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 148269572 Common - modification methylase, HemK family Tpet_0432 226 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 148270101 Common - binding-protein-dependent transport systems inner membrane component Tpet_0967 159 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148270867 Nonpathogen - hypothetical protein Tpet_1750 1 None None None 148269530 Common - binding-protein-dependent transport systems inner membrane component Tpet_0388 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269639 Common - binding-protein-dependent transport systems inner membrane component Tpet_0501 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148269645 Common - Creatininase Tpet_0507 79 COG1402 COG1402, Uncharacterized protein, putative amidase General function prediction only 148269567 Common - chromosome segregation and condensation protein ScpA Tpet_0427 141 COG1354 COG1354, Uncharacterized conserved protein Function unknown 148269817 Common - Radical SAM domain protein Tpet_0681 21 COG2516 COG2516, Biotin synthase-related enzyme General function prediction only 148269486 Common - GCN5-related N-acetyltransferase Tpet_0341 66 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 148270265 Nonpathogen - hypothetical protein Tpet_1135 2 None None None 148269581 Nonpathogen - preprotein translocase, SecG subunit Tpet_0441 5 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 148269588 Common - SNO glutamine amidotransferase Tpet_0448 98 COG0311 PDX2, Predicted glutamine amidotransferase involved in pyridoxine biosynthesis Coenzyme metabolism 148270173 Common - Threonine aldolase Tpet_1039 123 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 148270048 Common - Rubrerythrin Tpet_0914 8 COG1633 COG1633, Uncharacterized conserved protein Function unknown 148269609 Common - ribosomal protein L33 Tpet_0469 69 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 148269614 Common - phosphoribosylaminoimidazole carboxylase, catalytic subunit Tpet_0474 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 148269518 Common - threonine synthase Tpet_0374 188 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 148269287 Common - putative thiazole biosynthetic enzyme Tpet_0142 44 COG1635 THI4, Flavoprotein involved in thiazole biosynthesis Coenzyme metabolism 148269505 Common - Ferritin, Dps family protein Tpet_0360 21 COG2406 COG2406, Protein distantly related to bacterial ferritins General function prediction only 148269755 Common - gamma-glutamyl phosphate reductase Tpet_0619 198 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 148270124 Common - thiamine biosynthesis/tRNA modification protein ThiI Tpet_0990 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 148270501 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Tpet_1371 30 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 148270219 Common - heat shock protein DnaJ domain protein Tpet_1089 227 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 148270425 Common rplB 50S ribosomal protein L2 Tpet_1295 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 148270283 Common - ABC transporter related Tpet_1153 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148269468 Common - Xanthine/uracil/vitamin C permease Tpet_0323 135 COG2252 COG2252, Permeases General function prediction only 148270512 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Tpet_1382 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 148270060 Nonpathogen - hypothetical protein Tpet_0926 3 COG0851 MinE, Septum formation topological specificity factor Cell division and chromosome partitioning 148269740 Common - YHS domain protein Tpet_0603 17 COG3350 COG3350, Uncharacterized conserved protein Function unknown 148269304 Common - phosphoglucomutase/phosphomannomutase alpha/beta/alpha domain I Tpet_0159 243 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 148270750 Nonpathogen - hypothetical protein Tpet_1628 1 None None None 148270816 Common - CutA1 divalent ion tolerance protein Tpet_1695 113 COG1324 CutA, Uncharacterized protein involved in tolerance to divalent cations Inorganic ion transport and metabolism 148270374 Common - polysaccharide biosynthesis protein CapD Tpet_1244 213 COG1086 COG1086, Predicted nucleoside-diphosphate sugar epimerases Cell envelope biogenesis, outer membrane / Carbohydrate transport and metabolism 148269354 Common - Glycine hydroxymethyltransferase Tpet_0209 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 148269834 Common - protein of unknown function DUF554 Tpet_0698 47 COG1811 COG1811, Uncharacterized membrane protein, possible Na+ channel or pump General function prediction only 148269393 Common - peptidase M50 Tpet_0248 77 COG1994 SpoIVFB, Zn-dependent proteases General function prediction only 148270383 Common flgI flagellar basal body P-ring protein Tpet_1253 105 COG1706 FlgI, Flagellar basal-body P-ring protein Cell motility and secretion 148270237 Common - HflK protein Tpet_1107 189 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 148269801 Common - D-alanine--D-alanine ligase Tpet_0665 220 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 148269179 Common - Bacitracin resistance protein BacA Tpet_0034 193 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 148269726 Common - Amidohydrolase 3 Tpet_0589 74 COG1574 COG1574, Predicted metal-dependent hydrolase with the TIM-barrel fold General function prediction only 148269795 Common - excinuclease ABC, C subunit Tpet_0659 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 148270468 Common rpmA 50S ribosomal protein L27 Tpet_1338 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 148269170 Common - RNA polymerase, sigma 28 subunit, FliA/WhiG Tpet_0025 145 COG1191 FliA, DNA-directed RNA polymerase specialized sigma subunit Transcription 148269340 Common - tRNA (uracil-5-)-methyltransferase Gid Tpet_0195 120 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 148270164 Common - permease YjgP/YjgQ family protein Tpet_1030 55 COG0795 COG0795, Predicted permeases General function prediction only 148270202 Common argC N-acetyl-gamma-glutamyl-phosphate reductase Tpet_1069 221 COG0002 ArgC, Acetylglutamate semialdehyde dehydrogenase Amino acid transport and metabolism 148270755 Common - putative monovalent cation/H+ antiporter subunit B Tpet_1633 11 COG2111 MnhB, Multisubunit Na+/H+ antiporter, MnhB subunit Inorganic ion transport and metabolism 148270853 Common - hypothetical protein Tpet_1733 8 None None None 148270577 Nonpathogen - hypothetical protein Tpet_1448 1 None None None 148270664 Common - glycosyl transferase, family 2 Tpet_1540 21 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148269863 Common - PP-loop domain protein Tpet_0727 134 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 148269443 Nonpathogen - hypothetical protein Tpet_0298 8 COG2194 COG2194, Predicted membrane-associated, metal-dependent hydrolase General function prediction only 148269574 Common - protein of unknown function DUF77 Tpet_0434 13 COG0011 COG0011, Uncharacterized conserved protein Function unknown 148269954 Common - inner-membrane translocator Tpet_0819 159 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 148270727 Common - CBS domain containing protein Tpet_1605 220 COG0517 COG0517, FOG: CBS domain General function prediction only 148269697 Nonpathogen - glycosyl transferase, group 1 Tpet_0560 3 None None None 148270345 Nonpathogen - hypothetical protein Tpet_1215 2 None None None 148269414 Common - acyl carrier protein Tpet_0269 209 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148269936 Common - periplasmic solute binding protein Tpet_0801 165 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 148269401 Common - flagellar FlbD family protein Tpet_0256 29 COG1582 FlgEa, Uncharacterized protein, possibly involved in motility Cell motility and secretion 148269205 Nonpathogen - hypothetical protein Tpet_0060 1 None None None 148270141 Nonpathogen - hypothetical protein Tpet_1007 1 None None None 148269621 Common - transcriptional regulator, GntR family Tpet_0481 133 COG1802 GntR, Transcriptional regulators Transcription 148270822 Common - peptidase M42 family protein Tpet_1701 80 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 148270004 Common - Alpha-glucuronidase Tpet_0869 15 COG3661 AguA, Alpha-glucuronidase Carbohydrate transport and metabolism 148270897 Common - ExsB family protein Tpet_1781 71 COG1606 COG1606, ATP-utilizing enzymes of the PP-loop superfamily General function prediction only 148269327 Common - carboxyl-terminal protease Tpet_0182 188 COG0793 Prc, Periplasmic protease Cell envelope biogenesis, outer membrane 148270030 Common - ABC transporter related Tpet_0896 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270906 Common - periplasmic binding protein/LacI transcriptional regulator Tpet_1790 129 COG1609 PurR, Transcriptional regulators Transcription 148270524 Common - putative methyltransferase Tpet_1395 214 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 148269889 Common - hydrolase, HAD-superfamily, subfamily IIIA Tpet_0754 40 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 148270763 Common - Ribonuclease III Tpet_1641 216 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 148270273 Common - metal dependent phosphohydrolase Tpet_1143 42 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 148270698 Common - HAD-superfamily hydrolase, subfamily IA, variant 1 Tpet_1576 165 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 148269222 Common - GrpE protein Tpet_0077 202 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 148269400 Common - MotA/TolQ/ExbB proton channel Tpet_0255 91 COG1291 MotA, Flagellar motor component Cell motility and secretion 148269163 Common - flagellar biosynthetic protein FlhB Tpet_0018 130 COG1377 FlhB, Flagellar biosynthesis pathway, component FlhB Cell motility and secretion / Intracellular trafficking and secretion 148269451 Common - polysaccharide biosynthesis protein Tpet_0306 70 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 148270628 Common thiH thiamine biosynthesis protein ThiH Tpet_1504 59 COG1060 ThiH, Thiamine biosynthesis enzyme ThiH and related uncharacterized enzymes Coenzyme metabolism / General function prediction only 148270108 Common - metal dependent phosphohydrolase Tpet_0974 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 148270043 Common - methyl-accepting chemotaxis sensory transducer Tpet_0909 164 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148270186 Common nusB transcription antitermination protein NusB Tpet_1053 120 COG0781 NusB, Transcription termination factor Transcription 148269680 Common - heat shock protein Hsp20 Tpet_0543 109 COG0071 IbpA, Molecular chaperone (small heat shock protein) Posttranslational modification, protein turnover, chaperones 148270230 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Tpet_1100 22 COG1146 COG1146, Ferredoxin Energy production and conversion 148269458 Common - ribosomal protein S18 Tpet_0313 213 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 148269941 Common - ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent Tpet_0806 223 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 148270569 Common - hypothetical protein Tpet_1440 7 None None None 148269848 Common - glycine cleavage system H protein Tpet_0712 186 COG0509 GcvH, Glycine cleavage system H protein (lipoate-binding) Amino acid transport and metabolism 148270572 Nonpathogen - hypothetical protein Tpet_1443 1 None None None 148269619 Common - short-chain dehydrogenase/reductase SDR Tpet_0479 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148270252 Nonpathogen - hypothetical protein Tpet_1122 1 None None None 148270585 Common - Radical SAM domain protein Tpet_1456 113 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 148270776 Common - TrkA-N domain protein Tpet_1655 145 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 148270487 Common - dimethyladenosine transferase Tpet_1357 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 148270709 Common - beta-lactamase domain protein Tpet_1587 135 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 148270650 Common - phosphoribosylformylglycinamidine synthase I Tpet_1526 228 COG0047 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, glutamine amidotransferase domain Nucleotide transport and metabolism 148270659 Common - binding-protein-dependent transport systems inner membrane component Tpet_1535 174 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148270135 Common - lysyl-tRNA synthetase Tpet_1001 249 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 148270653 Nonpathogen - hypothetical protein Tpet_1529 3 None None None 148270259 Common - stationary-phase survival protein SurE Tpet_1129 186 COG0496 SurE, Predicted acid phosphatase General function prediction only 148270057 Common - putative cold-shock DNA-binding domain protein Tpet_0923 181 COG1278 CspC, Cold shock proteins Transcription 148270563 Common - protein of unknown function UPF0118 Tpet_1434 97 COG0628 PerM, Predicted permease General function prediction only 148269709 Common - Shikimate kinase., 3-dehydroquinate synthase Tpet_0572 212 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 148269203 Common - thioredoxin reductase Tpet_0058 248 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 148270242 Common - riboflavin synthase subunit alpha Tpet_1112 209 COG0307 RibC, Riboflavin synthase alpha chain Coenzyme metabolism 148270058 Common - Orn/DAP/Arg decarboxylase 2 Tpet_0924 214 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 148269887 Common - reverse gyrase Tpet_0752 232 COG1110 COG1110, Reverse gyrase DNA replication, recombination, and repair 148270766 Common - dTMP kinase Tpet_1644 234 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 148270053 Common ushA bifunctional UDP-sugar hydrolase/5'-nucleotidase periplasmic precursor Tpet_0919 143 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 148269600 Common - 4-phytase Tpet_0460 183 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148270890 Nonpathogen - hypothetical protein Tpet_1774 1 None None None 148270588 Nonpathogen - hypothetical protein Tpet_1459 1 None None None 148270176 Common - Phosphate butyryltransferase Tpet_1042 140 COG0280 Pta, Phosphotransacetylase Energy production and conversion 148270724 Common - isocitrate dehydrogenase Tpet_1602 135 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 148270656 Common - UvrD/REP helicase Tpet_1532 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 148270660 Common - binding-protein-dependent transport systems inner membrane component Tpet_1536 129 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148270771 Common - arginyl-tRNA synthetase Tpet_1650 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148270695 Nonpathogen - hypothetical protein Tpet_1573 4 None None None 148269208 Common - ribonuclease Z Tpet_0063 73 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 148269587 Common - pyridoxine biosynthesis protein Tpet_0447 87 COG0214 SNZ1, Pyridoxine biosynthesis enzyme Coenzyme metabolism 148270221 Common - hypothetical protein Tpet_1091 3 None None None 148270646 Common - IMP cyclohydrolase Tpet_1522 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 148269214 Common - hypothetical protein Tpet_0069 6 None None None 148269839 Common - flagellar M-ring protein FliF Tpet_0703 125 COG1766 FliF, Flagellar biosynthesis/type III secretory pathway lipoprotein Cell motility and secretion / Intracellular trafficking and secretion 148269432 Nonpathogen - hypothetical protein Tpet_0287 4 None None None 148269423 Common - RNA modification enzyme, MiaB family Tpet_0278 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 148269940 Common - Acetamidase/Formamidase Tpet_0805 63 COG2421 COG2421, Predicted acetamidase/formamidase Energy production and conversion 148270729 Common - ABC transporter related Tpet_1607 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148270481 Common - cytidylate kinase Tpet_1351 214 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 148269410 Common - serine O-acetyltransferase Tpet_0265 187 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 148270331 Common rplT 50S ribosomal protein L20 Tpet_1201 216 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 148269628 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_0488 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270597 Nonpathogen - protein of unknown function UPF0150 Tpet_1470 1 COG1598 COG1598, Uncharacterized conserved protein Function unknown 148269792 Common - homocysteine S-methyltransferase Tpet_0656 179 COG1410 MetH, Methionine synthase I, cobalamin-binding domain Amino acid transport and metabolism 148270324 Common - RNA polymerase, sigma-24 subunit, ECF subfamily Tpet_1194 162 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 148270200 Common - Argininosuccinate synthase Tpet_1067 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 148270548 Common - flagellar basal-body rod protein FlgB Tpet_1419 32 COG1815 FlgB, Flagellar basal body protein Cell motility and secretion 148270228 Nonpathogen - CRISPR-associated protein DxTHG motif Tpet_1098 15 None None None 148270881 Common - metal dependent phosphohydrolase Tpet_1765 122 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 148269166 Common - Cobyrinic acid a,c-diamide synthase Tpet_0021 112 COG0455 COG0455, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 148269419 Common - Rubrerythrin Tpet_0274 79 COG1592 COG1592, Rubrerythrin Energy production and conversion 148270281 Common - putative oxidoreductase Tpet_1151 240 COG0493 GltD, NADPH-dependent glutamate synthase beta chain and related oxidoreductases Amino acid transport and metabolism / General function prediction only 148269997 Nonpathogen - Carbohydrate-binding, CenC domain protein Tpet_0862 1 None None None 148270118 Nonpathogen - DNA-directed RNA polymerase, omega subunit Tpet_0984 4 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 148270199 Common - protein of unknown function DUF150 Tpet_1066 179 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 148269696 Common - biotin synthase Tpet_0559 185 COG0502 BioB, Biotin synthase and related enzymes Coenzyme metabolism 148270062 Common - peptidase S16, lon domain protein Tpet_0928 100 COG1067 LonB, Predicted ATP-dependent protease Posttranslational modification, protein turnover, chaperones 148269949 Common - ROK family protein Tpet_0814 160 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148270683 Common - Alpha-galactosidase-like protein Tpet_1560 35 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 148269585 Common - isochorismatase hydrolase Tpet_0445 150 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 148270161 Common - protein of unknown function YGGT Tpet_1027 67 COG0762 COG0762, Predicted integral membrane protein Function unknown 148270848 Common - protein of unknown function DUF6, transmembrane Tpet_1727 172 COG5006 COG5006, Predicted permease, DMT superfamily General function prediction only 148269711 Common - Shikimate dehydrogenase substrate binding, N-terminal domain protein Tpet_0574 196 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 148269190 Common - O-acetylhomoserine/O-acetylserine sulfhydrylase Tpet_0045 208 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 148269188 Common - Radical SAM domain protein Tpet_0043 82 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 148270125 Common - Tetratricopeptide TPR_2 repeat protein Tpet_0991 147 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 148269832 Common - NADH dehydrogenase (quinone) Tpet_0696 170 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 148270064 Common - L-lactate dehydrogenase Tpet_0930 172 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 148270785 Common - ribose 5-phosphate isomerase B Tpet_1664 127 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 148270208 Nonpathogen - hypothetical protein Tpet_1076 1 None None None 148270555 Common - protein of unknown function UPF0027 Tpet_1426 119 COG1690 RtcB, Uncharacterized conserved protein Function unknown 148270466 Common - ribosomal protein L21 Tpet_1336 204 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 148270927 Nonpathogen - hypothetical protein Tpet_1811 1 None None None 148270096 Nonpathogen - hypothetical protein Tpet_0962 3 None None None 148269736 Nonpathogen - Heavy metal transport/detoxification protein Tpet_0599 3 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 148270818 Common - ABC transporter related Tpet_1697 249 COG1137 YhbG, ABC-type (unclassified) transport system, ATPase component General function prediction only 148270379 Common - protein of unknown function DUF1078 domain protein Tpet_1249 126 COG4786 FlgG, Flagellar basal body rod protein Cell motility and secretion 148269402 Common - protein of unknown function DUF1078 domain protein Tpet_0257 126 COG1749 FlgE, Flagellar hook protein FlgE Cell motility and secretion 148269564 Common - DNA polymerase III, epsilon subunit Tpet_0424 194 COG0847 DnaQ, DNA polymerase III, epsilon subunit and related 3'-5' exonucleases DNA replication, recombination, and repair 148269394 Common - polysaccharide pyruvyl transferase Tpet_0249 15 COG2327 WcaK, Uncharacterized conserved protein Function unknown 148270236 Common - N-glycosylase/DNA lyase Tpet_1106 14 COG1059 COG1059, Thermostable 8-oxoguanine DNA glycosylase DNA replication, recombination, and repair 148269172 Nonpathogen - hypothetical protein Tpet_0027 5 None None None 148270139 Common - protein of unknown function UPF0052 and CofD Tpet_1005 98 COG0391 COG0391, Uncharacterized conserved protein Function unknown 148269444 Common - glycosyl transferase, group 1 Tpet_0299 11 None None None 148269161 Common - putative translation initiation factor, aIF-2BI family Tpet_0016 132 COG0182 COG0182, Predicted translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 148269605 Common rplA 50S ribosomal protein L1 Tpet_0465 249 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 148269378 Common - flagellar biosynthetic protein FliQ Tpet_0233 27 COG1987 FliQ, Flagellar biosynthesis pathway, component FliQ Cell motility and secretion / Intracellular trafficking and secretion 148270140 Common - hypothetical protein Tpet_1006 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 148270623 Common - glutamyl-tRNA(Gln) amidotransferase, A subunit Tpet_1499 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 148270422 Common - ribosomal protein L3 Tpet_1292 248 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 148270103 Common - alpha amylase, catalytic region Tpet_0969 166 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 148269570 Common - Silent information regulator protein Sir2 Tpet_0430 152 COG0846 SIR2, NAD-dependent protein deacetylases, SIR2 family Transcription 148270264 Common - ribosomal protein S20 Tpet_1134 174 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 148269664 Common - glutamate synthase, alpha subunit domain protein Tpet_0526 120 COG0070 GltB, Glutamate synthase domain 3 Amino acid transport and metabolism 148269331 Nonpathogen - hypothetical protein Tpet_0186 4 None None None 148269899 Common - Polyprenyl synthetase Tpet_0764 242 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 148270902 Common - DNA mismatch repair protein MutS domain protein Tpet_1786 199 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 148270823 Common - Cellulase Tpet_1702 89 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 148270338 Common - phosphoribosyltransferase Tpet_1208 115 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 148270253 Common - protein of unknown function DUF192 Tpet_1123 90 COG1430 COG1430, Uncharacterized conserved protein Function unknown 148269990 Common - mannonate dehydratase Tpet_0855 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 148269338 Common - mannose-6-phosphate isomerase, type I Tpet_0193 47 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 148269661 Common - Glutamate synthase (NADPH) Tpet_0523 203 COG0069 GltB, Glutamate synthase domain 2 Amino acid transport and metabolism 148270494 Common - glycerol kinase Tpet_1364 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 148269991 Common - Mannitol dehydrogenase, C-terminal domain Tpet_0856 80 COG0246 MtlD, Mannitol-1-phosphate/altronate dehydrogenases Carbohydrate transport and metabolism 148270651 Common - phosphoribosylformylglycinamidine synthase, purS Tpet_1527 51 COG1828 PurS, Phosphoribosylformylglycinamidine (FGAM) synthase, PurS component Nucleotide transport and metabolism 148269377 Common fliP flagellar biosynthesis protein FliP Tpet_0232 128 COG1338 FliP, Flagellar biosynthesis pathway, component FliP Cell motility and secretion / Intracellular trafficking and secretion 148270349 Common - Pyrrolo-quinoline quinone Tpet_1219 41 COG1520 COG1520, FOG: WD40-like repeat Function unknown 148270888 Common - Adenine-specific DNA methylase containing a Zn-ribbon-like protein Tpet_1772 51 COG1743 COG1743, Adenine-specific DNA methylase containing a Zn-ribbon DNA replication, recombination, and repair 148270613 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase Tpet_1489 145 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 148270637 Common - histidine kinase Tpet_1513 217 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148270841 Common - transcriptional regulator, TetR family Tpet_1720 125 COG1309 AcrR, Transcriptional regulator Transcription 148270641 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Tpet_1517 200 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 148269507 Common - carbamoyl-phosphate synthase, large subunit Tpet_0363 237 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 148270340 Common - protein of unknown function DUF458 Tpet_1210 14 COG1978 COG1978, Uncharacterized protein conserved in bacteria Function unknown 148270687 Nonpathogen - hypothetical protein Tpet_1565 1 None None None 148269725 Common pyrE orotate phosphoribosyltransferase Tpet_0588 131 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 148269470 Common - polar amino acid ABC transporter, inner membrane subunit Tpet_0325 180 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 148269638 Common - ABC transporter related Tpet_0500 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 148270035 Common - DNA mismatch repair protein MutL Tpet_0901 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 148270402 Common - Dihydrodipicolinate reductase Tpet_1272 216 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 148270327 Common - phosphoesterase, RecJ domain protein Tpet_1197 83 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 148269743 Nonpathogen - hypothetical protein Tpet_0606 2 None None None 148270454 Common - degV family protein Tpet_1324 55 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 148269626 Common - binding-protein-dependent transport systems inner membrane component Tpet_0486 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269229 Common - glutamate formiminotransferase Tpet_0084 22 COG3643 COG3643, Glutamate formiminotransferase Amino acid transport and metabolism 148270366 Common - maf protein Tpet_1236 197 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 148270433 Common rplX 50S ribosomal protein L24 Tpet_1303 212 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 148270791 Common - glycoside hydrolase family 2, sugar binding Tpet_1670 8 None None None 148270803 Common - alpha-L-rhamnosidase Tpet_1682 24 COG3408 GDB1, Glycogen debranching enzyme Carbohydrate transport and metabolism 148270145 Common - radical SAM enzyme, Cfr family Tpet_1011 195 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 148269279 Nonpathogen - hypothetical protein Tpet_0134 4 COG3368 COG3368, Predicted permease General function prediction only 148270526 Nonpathogen - hypothetical protein Tpet_1397 1 None None None 148269779 Common - protein of unknown function DUF1680 Tpet_0643 33 COG3533 COG3533, Uncharacterized protein conserved in bacteria Function unknown 148269285 Nonpathogen - Xylose isomerase domain protein TIM barrel Tpet_0140 3 COG1082 IolE, Sugar phosphate isomerases/epimerases Carbohydrate transport and metabolism 148269398 Nonpathogen - flagellar basal body-associated protein FliL Tpet_0253 4 COG1580 FliL, Flagellar basal body-associated protein Cell motility and secretion 148269241 Common - aminotransferase, class IV Tpet_0096 187 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 148269529 Common - RNA polymerase factor sigma-70 Tpet_0387 78 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 148269952 Common - putative diguanylate cyclase Tpet_0817 7 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 148269371 Common - Protein-L-isoaspartate(D-aspartate) O-methyltransferase Tpet_0226 171 COG2518 Pcm, Protein-L-isoaspartate carboxylmethyltransferase Posttranslational modification, protein turnover, chaperones 148269254 Common - glycosyl transferase, WecB/TagA/CpsF family Tpet_0109 112 COG1922 WecG, Teichoic acid biosynthesis proteins Cell envelope biogenesis, outer membrane 148270798 Common - extracellular solute-binding protein, family 5 Tpet_1677 170 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148270514 Common - ribosome recycling factor Tpet_1384 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 148269538 Common - tRNA delta(2)-isopentenylpyrophosphate transferase Tpet_0396 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 148270443 Common - Nucleoside-triphosphate--adenylate kinase Tpet_1313 231 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 148269748 Common - Alpha-L-fucosidase Tpet_0611 33 COG3669 COG3669, Alpha-L-fucosidase Carbohydrate transport and metabolism 148270385 Common - Radical SAM domain protein Tpet_1255 118 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 148269258 Common - MATE efflux family protein Tpet_0113 190 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 148270871 Common - hypothetical protein Tpet_1754 29 COG4930 COG4930, Predicted ATP-dependent Lon-type protease Posttranslational modification, protein turnover, chaperones 148270099 Common - alpha amylase, catalytic region Tpet_0965 171 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 148269380 Common - ATP-dependent Clp protease, proteolytic subunit ClpP Tpet_0235 211 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148269751 Common - short-chain dehydrogenase/reductase SDR Tpet_0615 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148269776 Common - hypothetical protein Tpet_0640 12 None None None 148269433 Common - HAD-superfamily hydrolase, subfamily IA, variant 3 Tpet_0288 74 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 148270213 Common - CRISPR-associated protein Cas4 Tpet_1083 34 COG1468 COG1468, RecB family exonuclease DNA replication, recombination, and repair 148269488 Common - crossover junction endodeoxyribonuclease RuvC Tpet_0343 198 COG0817 RuvC, Holliday junction resolvasome, endonuclease subunit DNA replication, recombination, and repair 148270111 Nonpathogen - hypothetical protein Tpet_0977 1 None None None 148269717 Common - Uncharacterized protein-like protein Tpet_0580 17 COG3877 COG3877, Uncharacterized protein conserved in bacteria Function unknown 148270086 Common - Beta-glucosidase Tpet_0952 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 148270361 Common - queuine tRNA-ribosyltransferase Tpet_1231 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 148269344 Common - D-tyrosyl-tRNA deacylase Tpet_0199 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 148270911 Nonpathogen - Radical SAM domain protein Tpet_1795 10 COG5014 COG5014, Predicted Fe-S oxidoreductase General function prediction only 148270448 Common - 30S ribosomal protein S11 Tpet_1318 248 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 148269298 Common infB translation initiation factor IF-2 Tpet_0153 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 148270810 Common - Beta-glucuronidase Tpet_1689 76 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 148269758 Common - 2-methylcitrate synthase/citrate synthase II Tpet_0622 194 COG0372 GltA, Citrate synthase Energy production and conversion 148270006 Nonpathogen - hypothetical protein Tpet_0871 3 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 148270409 Common - protein of unknown function DUF795 Tpet_1279 27 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 148270315 Common - sigma 54 modulation protein/ribosomal protein S30EA Tpet_1185 147 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 148270090 Common - binding-protein-dependent transport systems inner membrane component Tpet_0956 212 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148270887 Nonpathogen - hypothetical protein Tpet_1771 1 None None None 148270736 Common - putative transcriptional regulator, GntR family Tpet_1614 228 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 148269234 Nonpathogen - S-layer domain-like protein Tpet_0089 4 COG1361 COG1361, S-layer domain Cell envelope biogenesis, outer membrane 148270453 Common - ROK family protein Tpet_1323 157 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148269477 Common - protein of unknown function DUF6, transmembrane Tpet_0332 119 COG0697 RhaT, Permeases of the drug/metabolite transporter (DMT) superfamily Carbohydrate transport and metabolism / Amino acid transport and metabolism / General function prediction only 148269220 Common - Sua5/YciO/YrdC/YwlC family protein Tpet_0075 244 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 148269877 Common - Radical SAM domain protein Tpet_0742 222 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 148269579 Nonpathogen - hypothetical protein Tpet_0439 13 COG1906 COG1906, Uncharacterized conserved protein Function unknown 148270045 Common - NADH dehydrogenase (ubiquinone), 24 kDa subunit Tpet_0911 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 148269784 Common - L-arabinose isomerase Tpet_0648 35 COG2160 AraA, L-arabinose isomerase Carbohydrate transport and metabolism 148269901 Common - non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family Tpet_0766 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 148269739 Nonpathogen - membrane protein-like protein Tpet_0602 12 COG3462 COG3462, Predicted membrane protein Function unknown 148270900 Common - oligoendopeptidase, M3 family Tpet_1784 89 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 148270618 Common - cell division protein FtsA Tpet_1494 162 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 148270475 Common - Tetratricopeptide TPR_2 repeat protein Tpet_1345 11 COG4783 COG4783, Putative Zn-dependent protease, contains TPR repeats General function prediction only 148269542 Common - ATP-dependent protease peptidase subunit Tpet_0400 149 COG5405 HslV, ATP-dependent protease HslVU (ClpYQ), peptidase subunit Posttranslational modification, protein turnover, chaperones 148269989 Common - Endo-1,4-beta-xylanase Tpet_0854 34 COG3693 XynA, Beta-1,4-xylanase Carbohydrate transport and metabolism 148269158 Common - protein of unknown function DUF47 Tpet_0013 69 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 148270748 Common - type II and III secretion system protein Tpet_1626 139 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 148269191 Common - homoserine O-succinyltransferase Tpet_0046 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 148269362 Nonpathogen - hypothetical protein Tpet_0217 3 None None None 148270226 Common - CRISPR-associated protein, Csm2 family Tpet_1096 3 COG1421 COG1421, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 148269821 Common - glucose-1-phosphate adenylyltransferase, GlgD subunit Tpet_0685 223 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 148270702 Common - short-chain dehydrogenase/reductase SDR Tpet_1580 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 148270674 Common - periplasmic binding protein/LacI transcriptional regulator Tpet_1550 131 COG1609 PurR, Transcriptional regulators Transcription 148269657 Common - Thymidine kinase Tpet_0519 89 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 148270305 Common - ATP synthase F0, A subunit Tpet_1175 148 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 148269875 Common - phosphoglucosamine mutase Tpet_0740 239 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 148270757 Nonpathogen - hypothetical protein Tpet_1635 1 COG1320 MnhG, Multisubunit Na+/H+ antiporter, MnhG subunit Inorganic ion transport and metabolism 148270163 Common - phosphate uptake regulator, PhoU Tpet_1029 175 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 148270603 Common - ABC-2 type transporter Tpet_1478 20 COG1511 COG1511, Predicted membrane protein Function unknown 148269650 Common - chemotaxis-specific methylesterase Tpet_0512 219 COG2201 CheB, Chemotaxis response regulator containing a CheY-like receiver domain and a methylesterase domain Cell motility and secretion / Signal transduction mechanisms 148270137 Common - hypothetical protein Tpet_1003 176 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 148269851 Common - 6-phosphofructokinase Tpet_0715 156 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 148269247 Common - Radical SAM domain protein Tpet_0102 183 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 148269593 Common - Stage II sporulation E family protein Tpet_0453 111 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 148270491 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Tpet_1361 43 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 148269268 Common - glycosyl transferase, family 4 Tpet_0123 145 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 148270537 Common - extracellular solute-binding protein, family 1 Tpet_1408 136 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 148269905 Common - Alkaline phosphatase Tpet_0770 86 COG1785 PhoA, Alkaline phosphatase Inorganic ion transport and metabolism 148269707 Common - Lysine exporter protein (LYSE/YGGA) Tpet_0570 26 COG1280 RhtB, Putative threonine efflux protein Amino acid transport and metabolism 148269510 Common - 3-isopropylmalate dehydratase, large subunit Tpet_0366 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 148269631 Common - NADH:flavin oxidoreductase/NADH oxidase Tpet_0492 175 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 148270017 Common - dihydropteroate synthase Tpet_0883 220 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 148270510 Common - daunorubicin resistance ABC transporter, inner membrane subunit B Tpet_1380 202 COG1511 COG1511, Predicted membrane protein Function unknown 148269938 Common - lysine 2,3-aminomutase YodO family protein Tpet_0803 127 COG1509 KamA, Lysine 2,3-aminomutase Amino acid transport and metabolism 148270579 Nonpathogen - hypothetical protein Tpet_1450 1 None None None 148270669 Common - extracellular solute-binding protein, family 5 Tpet_1545 196 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148270299 Nonpathogen - hypothetical protein Tpet_1169 3 None None None 148270194 Common - TPR repeat-containing protein Tpet_1061 61 COG2956 COG2956, Predicted N-acetylglucosaminyl transferase Carbohydrate transport and metabolism 148269389 Nonpathogen - conserved hypothetical protein 103 Tpet_0244 3 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 148269928 Common - flagellin domain protein Tpet_0793 99 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 148270869 Common - hypothetical protein Tpet_1752 6 None None None 148270290 Common - protein of unknown function DUF72 Tpet_1160 102 COG1801 COG1801, Uncharacterized conserved protein Function unknown 148270892 Common - ATPase (AAA+ superfamily)-like protein Tpet_1776 36 COG1483 COG1483, Predicted ATPase (AAA+ superfamily) General function prediction only 148269369 Common - protein of unknown function DUF214 Tpet_0224 16 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 148269805 Common - ribosomal protein L28 Tpet_0669 65 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 148269820 Common glgC glucose-1-phosphate adenylyltransferase Tpet_0684 222 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 148269678 Common - protein of unknown function DUF81 Tpet_0541 192 COG0730 COG0730, Predicted permeases General function prediction only 148270808 Common - extracellular solute-binding protein, family 5 Tpet_1687 163 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148270696 Common - flagellar protein FliS Tpet_1574 93 COG1516 FliS, Flagellin-specific chaperone FliS Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 148269272 Common - beta-hydroxyacyl-(acyl-carrier-protein) dehydratase FabZ Tpet_0127 186 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 148269519 Common - homoserine kinase Tpet_0375 121 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 148270377 Common - Holliday junction resolvase YqgF Tpet_1247 19 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 148269982 Common - Acetyl xylan esterase Tpet_0847 20 COG3458 COG3458, Acetyl esterase (deacetylase) Secondary metabolites biosynthesis, transport, and catabolism 148270621 Nonpathogen - hypothetical protein Tpet_1497 1 None None None 148269763 Common - Glycerol-1-phosphate dehydrogenase (NAD(P)(+)) Tpet_0627 58 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 148269643 Common - PfkB domain protein Tpet_0505 6 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148270285 Common - SMC domain protein Tpet_1155 135 COG0419 SbcC, ATPase involved in DNA repair DNA replication, recombination, and repair 148269313 Common - glycosyl transferase, group 1 Tpet_0168 71 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148270395 Common - transcriptional regulator, BadM/Rrf2 family Tpet_1265 166 COG1959 COG1959, Predicted transcriptional regulator Transcription 148269293 Common - alkyl hydroperoxide reductase/ Thiol specific antioxidant/ Mal allergen Tpet_0148 226 COG1225 Bcp, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148270576 Common - Radical SAM domain protein Tpet_1447 60 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 148269323 Common - phosphoribulokinase/uridine kinase Tpet_0178 111 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 148269950 Common - Radical SAM domain protein Tpet_0815 40 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 148269790 Common - methylenetetrahydrofolate reductase Tpet_0654 66 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 148269165 Common flhF flagellar biosynthesis regulator FlhF Tpet_0020 247 COG1419 FlhF, Flagellar GTP-binding protein Cell motility and secretion 148269146 Common - chromosomal replication initiator protein DnaA Tpet_0001 215 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 148269352 Common - ribonuclease R Tpet_0207 196 COG0557 VacB, Exoribonuclease R Transcription 148270312 Common - H+-transporting two-sector ATPase, delta/epsilon subunit Tpet_1182 39 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 148270693 Common - chromosome segregation protein SMC Tpet_1571 209 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 148270262 Nonpathogen - hypothetical protein Tpet_1132 4 None None None 148269201 Nonpathogen - hypothetical protein Tpet_0056 1 None None None 148270234 Common - Chromate transporter Tpet_1104 65 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 148269417 Common - Rubredoxin-type Fe(Cys)4 protein Tpet_0272 125 COG1773 COG1773, Rubredoxin Energy production and conversion 148270533 Common - seryl-tRNA synthetase Tpet_1404 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 148269421 Common - Adenosylmethionine decarboxylase Tpet_0276 74 COG1586 SpeD, S-adenosylmethionine decarboxylase Amino acid transport and metabolism 148270047 Common - NADH dehydrogenase (quinone) Tpet_0913 196 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 148270680 Common - Beta-galactosidase Tpet_1557 39 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 148270496 Common - redox-sensing transcriptional repressor Rex Tpet_1366 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 148269933 Common - two component transcriptional regulator, winged helix family Tpet_0798 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148269182 Common - peptidase M50 Tpet_0037 209 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 148270347 Nonpathogen - FOG: WD40-like repeat-like protein Tpet_1217 3 COG1520 COG1520, FOG: WD40-like repeat Function unknown 148270372 Common - protein of unknown function DUF1385 Tpet_1242 31 COG3872 COG3872, Predicted metal-dependent enzyme General function prediction only 148269493 Common - signal recognition particle-docking protein FtsY Tpet_0348 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 148269375 Common - response regulator receiver protein Tpet_0230 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 148270488 Common - glycerol-3-phosphate responsive antiterminator Tpet_1358 21 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 148269897 Nonpathogen - Tetratricopeptide TPR_2 repeat protein Tpet_0762 3 COG4105 ComL, DNA uptake lipoprotein General function prediction only 148269524 Common - tryptophan synthase subunit beta Tpet_0382 225 COG1350 COG1350, Predicted alternative tryptophan synthase beta-subunit (paralog of TrpB) General function prediction only 148270178 Common - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Tpet_1045 62 COG1146 COG1146, Ferredoxin Energy production and conversion 148270483 Common - aspartyl-tRNA synthetase Tpet_1353 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148269151 Common - Lytic transglycosylase, catalytic Tpet_0006 158 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 148269481 Common - Radical SAM domain protein Tpet_0336 59 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 148270768 Common - Adenylosuccinate synthase Tpet_1647 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 148270725 Nonpathogen - Thioredoxin-related protein-like protein Tpet_1603 5 COG2143 COG2143, Thioredoxin-related protein Posttranslational modification, protein turnover, chaperones 148270565 Common - inosine-5'-monophosphate dehydrogenase Tpet_1436 243 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 148270464 Common - single-stranded nucleic acid binding R3H domain protein Tpet_1334 66 COG1847 Jag, Predicted RNA-binding protein General function prediction only 148269602 Common - DNA-directed RNA polymerase, beta subunit Tpet_0462 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 148270783 Common - SOS-response transcriptional repressor, LexA Tpet_1662 173 COG1974 LexA, SOS-response transcriptional repressors (RecA-mediated autopeptidases) Transcription / Signal transduction mechanisms 148270244 Common - diguanylate cyclase Tpet_1114 160 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 148270105 Common - hypothetical protein Tpet_0971 14 None None None 148269845 Common - putative endoribonuclease L-PSP Tpet_0709 185 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 148269673 Common - Anaerobic ribonucleoside-triphosphate reductase activator Tpet_0535 8 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 148270278 Common - L-aspartate dehydrogenase Tpet_1148 49 COG1712 COG1712, Predicted dinucleotide-utilizing enzyme General function prediction only 148269454 Common - hypothetical protein Tpet_0309 16 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148270189 Common - exodeoxyribonuclease VII, large subunit Tpet_1056 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 148269404 Common - flagellar hook-length control protein Tpet_0259 17 COG3144 FliK, Flagellar hook-length control protein Cell motility and secretion 148269405 Nonpathogen - hypothetical protein Tpet_0260 7 COG3334 COG3334, Uncharacterized conserved protein Function unknown 148269670 Common - dihydrolipoamide dehydrogenase Tpet_0532 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 148270333 Common infC translation initiation factor IF-3 Tpet_1203 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 148270184 Common - translation elongation factor P Tpet_1051 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 148269984 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_0849 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 148270255 Common - succinyl-diaminopimelate desuccinylase Tpet_1125 216 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 148269333 Common - pantetheine-phosphate adenylyltransferase Tpet_0188 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 148270821 Nonpathogen - hypothetical protein Tpet_1700 2 None None None 148270416 Common - hypothetical protein Tpet_1286 5 None None None 148270915 Common - glutamine synthetase, type I Tpet_1799 231 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 148270438 Common - ribosomal protein L18 Tpet_1308 222 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 148270429 Common rplP 50S ribosomal protein L16 Tpet_1299 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 148270077 Nonpathogen - hypothetical protein Tpet_0943 1 None None None 148269509 Common - 3-isopropylmalate dehydratase, small subunit Tpet_0365 213 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 148270352 Common - Uncharacterized protein-like protein Tpet_1222 20 COG4752 COG4752, Uncharacterized protein conserved in bacteria Function unknown 148270271 Common - alpha amylase, catalytic region Tpet_1141 178 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 148270663 Nonpathogen - glycosyl transferase, group 1 Tpet_1539 5 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148270391 Common - Electron transfer flavoprotein, alpha subunit-like protein Tpet_1261 153 COG2025 FixB, Electron transfer flavoprotein, alpha subunit Energy production and conversion 148270381 Common - SAF domain Tpet_1251 24 COG1261 FlgA, Flagellar basal body P-ring biosynthesis protein Cell motility and secretion / Posttranslational modification, protein turnover, chaperones 148270899 Common - hypothetical protein Tpet_1783 64 COG1641 COG1641, Uncharacterized conserved protein Function unknown 148270018 Common - protein of unknown function DUF198 Tpet_0884 79 COG1469 COG1469, Uncharacterized conserved protein Function unknown 148270522 Common - ATPase AAA-2 domain protein Tpet_1392 216 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 148270132 Nonpathogen - hypothetical protein Tpet_0998 1 None None None 148270179 Common - 2-ketoisovalerate ferredoxin reductase Tpet_1046 131 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 148269865 Common - Ppx/GppA phosphatase Tpet_0729 81 COG0248 GppA, Exopolyphosphatase Nucleotide transport and metabolism / Inorganic ion transport and metabolism 148269813 Common - SoxR-reducing system protein RsxE Tpet_0677 76 COG4660 RnfE, Predicted NADH:ubiquinone oxidoreductase, subunit RnfE Energy production and conversion 148269723 Common - dihydroorotate dehydrogenase family protein Tpet_0586 231 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 148269309 Nonpathogen - hypothetical protein Tpet_0164 4 None None None 148270611 Common - Methyltransferase type 11 Tpet_1487 85 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148269688 Common - protein of unknown function DUF124 Tpet_0551 77 COG2013 COG2013, Uncharacterized conserved protein Function unknown 148270865 Common - permease Tpet_1748 98 COG0701 COG0701, Predicted permeases General function prediction only 148269799 Common - phosphate transporter Tpet_0663 160 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 148269302 Common - DNA polymerase III gamma/tau subunits-like protein Tpet_0157 206 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 148270639 Common - ABC transporter related Tpet_1515 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148269745 Common - extracellular solute-binding protein, family 5 Tpet_0608 167 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148270011 Common - transposase, IS605 OrfB family Tpet_0877 77 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 148270608 Common - ribonuclease H Tpet_1484 20 COG3341 COG3341, Predicted double-stranded RNA/RNA-DNA hybrid binding protein General function prediction only 148270752 Nonpathogen - hypothetical protein Tpet_1630 2 None None None 148270553 Common - PAS/PAC sensor signal transduction histidine kinase Tpet_1424 222 COG5000 NtrY, Signal transduction histidine kinase involved in nitrogen fixation and metabolism regulation Signal transduction mechanisms 148269174 Nonpathogen - hypothetical protein Tpet_0029 3 None None None 148269583 Common - S-layer domain protein Tpet_0443 83 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 148269746 Common - alpha-xylosidase YicI Tpet_0609 82 COG1501 COG1501, Alpha-glucosidases, family 31 of glycosyl hydrolases Carbohydrate transport and metabolism 148269295 Nonpathogen - hypothetical protein Tpet_0150 2 None None None 148270127 Common - SAM-dependent methyltransferase-like protein Tpet_0993 133 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 148269856 Common - ABC transporter related Tpet_0720 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 148270388 Nonpathogen - hypothetical protein Tpet_1258 1 None None None 148269993 Common - 2-dehydro-3-deoxyphosphogluconate aldolase/4-hydroxy-2-oxoglutarate aldolase Tpet_0858 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 148269947 Common - Monosaccharide-transporting ATPase Tpet_0812 162 COG1172 AraH, Ribose/xylose/arabinose/galactoside ABC-type transport systems, permease components Carbohydrate transport and metabolism 148270420 Common - elongation factor Tu Tpet_1290 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 148270529 Common - 4-diphosphocytidyl-2C-methyl-D-erythritol kinase Tpet_1400 192 COG1947 IspE, 4-diphosphocytidyl-2C-methyl-D-erythritol 2-phosphate synthase Lipid metabolism 148270066 Common - Deoxyribonuclease V Tpet_0932 73 COG1515 Nfi, Deoxyinosine 3'endonuclease (endonuclease V) DNA replication, recombination, and repair 148270815 Common - TrkA-N domain protein Tpet_1694 209 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 148269256 Common - transcriptional regulator, MarR family Tpet_0111 118 COG1846 MarR, Transcriptional regulators Transcription 148269396 Common - CheC, inhibitor of MCP methylation Tpet_0251 127 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 148270858 Common - Cupin 2, conserved barrel domain protein Tpet_1740 68 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 148270206 Nonpathogen - hypothetical protein Tpet_1073 1 None None None 148270708 Common - diguanylate cyclase Tpet_1586 177 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 148269446 Nonpathogen - hypothetical protein Tpet_0301 1 None None None 148270625 Common - Cystathionine gamma-lyase Tpet_1501 207 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 148270907 Common - RbsD or FucU transport Tpet_1791 42 COG1869 RbsD, ABC-type ribose transport system, auxiliary component Carbohydrate transport and metabolism 148269500 Common - major facilitator superfamily MFS_1 Tpet_0355 39 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148269347 Common - peptidase U62, modulator of DNA gyrase Tpet_0202 159 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 148269549 Common - Mg chelatase, subunit ChlI Tpet_0409 203 COG0606 COG0606, Predicted ATPase with chaperone activity Posttranslational modification, protein turnover, chaperones 148269715 Common - major facilitator superfamily MFS_1 Tpet_0578 173 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148270167 Common - zinc/iron permease Tpet_1033 119 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 148270157 Common - 3-methyl-2-oxobutanoate hydroxymethyltransferase Tpet_1023 195 COG0413 PanB, Ketopantoate hydroxymethyltransferase Coenzyme metabolism 148269266 Common - peroxiredoxin Tpet_0121 219 COG0450 AhpC, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 148269212 Common - protein-export membrane protein SecD Tpet_0067 220 COG0342 SecD, Preprotein translocase subunit SecD Intracellular trafficking and secretion 148269926 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Tpet_0791 80 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 148270777 Common - TrkA-N domain protein Tpet_1656 137 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 148270913 Common - PhoPQ-activated pathogenicity-related protein-like protein Tpet_1797 15 COG4287 PqaA, PhoPQ-activated pathogenicity-related protein General function prediction only 148269540 Nonpathogen - hypothetical protein Tpet_0398 1 None None None 148269774 Common - hypothetical protein Tpet_0638 12 None None None 148270329 Common - diguanylate cyclase Tpet_1199 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 148269193 Nonpathogen - 4Fe-4S ferredoxin, iron-sulfur binding domain protein Tpet_0048 4 COG1245 COG1245, Predicted ATPase, RNase L inhibitor (RLI) homolog General function prediction only 148269448 Common - HEPN domain protein Tpet_0303 21 COG2250 COG2250, Uncharacterized conserved protein related to C-terminal domain of eukaryotic chaperone, SACSIN Function unknown 148270080 Common - binding-protein-dependent transport systems inner membrane component Tpet_0946 143 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148269435 Common - polysaccharide export protein Tpet_0290 69 COG1596 Wza, Periplasmic protein involved in polysaccharide export Cell envelope biogenesis, outer membrane 148270520 Common - 2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase Tpet_1390 193 COG1211 IspD, 4-diphosphocytidyl-2-methyl-D-erithritol synthase Lipid metabolism 148270527 Common - glucose-6-phosphate isomerase Tpet_1398 210 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 148269959 Common - DNA ligase, NAD-dependent Tpet_0824 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 148269552 Common - iron dependent repressor Tpet_0412 79 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 148269655 Common - nitrogen regulatory protein P-II Tpet_0517 186 COG0347 GlnK, Nitrogen regulatory protein PII Amino acid transport and metabolism 148269475 Common - cell shape determining protein, MreB/Mrl family Tpet_0330 236 COG1077 MreB, Actin-like ATPase involved in cell morphogenesis Cell division and chromosome partitioning 148270738 Common - Adenosylhomocysteine nucleosidase Tpet_1616 65 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 148270113 Common - putative cold-shock DNA-binding domain protein Tpet_0979 181 COG1278 CspC, Cold shock proteins Transcription 148270407 Common - ferric uptake regulator, Fur family Tpet_1277 154 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 148269226 Common - cytidine deaminase Tpet_0081 118 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 148269782 Common - ABC-type sugar transport system periplasmic component-like protein Tpet_0646 68 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148269807 Common - protein of unknown function UPF0102 Tpet_0671 116 COG0792 COG0792, Predicted endonuclease distantly related to archaeal Holliday junction resolvase DNA replication, recombination, and repair 148270000 Common - binding-protein-dependent transport systems inner membrane component Tpet_0865 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270596 Common - helix-turn-helix domain protein Tpet_1469 3 None None None 148270386 Nonpathogen - protein of unknown function DUF981 Tpet_1256 7 COG3374 COG3374, Predicted membrane protein Function unknown 148269885 Common - phosphopantetheine-binding Tpet_0750 162 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 148270917 Nonpathogen - hypothetical protein Tpet_1801 2 None None None 148270092 Common - WD-40 repeat protein Tpet_0958 52 COG2319 COG2319, FOG: WD40 repeat General function prediction only 148269428 Common - 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Tpet_0283 186 COG0245 IspF, 2C-methyl-D-erythritol 2,4-cyclodiphosphate synthase Lipid metabolism 148270197 Common - ferric uptake regulator, Fur family Tpet_1064 203 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 148270444 Common - methionine aminopeptidase, type I Tpet_1314 249 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 148270456 Common - metal dependent phosphohydrolase Tpet_1326 124 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 148269206 Common - band 7 protein Tpet_0061 221 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 148270368 Common - protein of unknown function DUF1312 Tpet_1238 6 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 148270801 Common - binding-protein-dependent transport systems inner membrane component Tpet_1680 157 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148270414 Common - metal dependent phosphohydrolase Tpet_1284 59 COG1480 COG1480, Predicted membrane-associated HD superfamily hydrolase General function prediction only 148270807 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_1686 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 148270431 Common rpsQ 30S ribosomal protein S17 Tpet_1301 240 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 148269545 Nonpathogen - hypothetical protein Tpet_0403 10 None None None 148270320 Common - 3H domain protein Tpet_1190 22 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 148270830 Common - Histidinol dehydrogenase Tpet_1709 214 COG0141 HisD, Histidinol dehydrogenase Amino acid transport and metabolism 148269841 Nonpathogen - Flagellar biosynthesis/type III secretory pathway protein-like protein Tpet_0705 3 COG1317 FliH, Flagellar biosynthesis/type III secretory pathway protein Cell motility and secretion / Intracellular trafficking and secretion 148269676 Common - ABC-2 type transporter Tpet_0539 14 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 148269624 Common - Alcohol dehydrogenase GroES domain protein Tpet_0484 205 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 148270827 Common - Citrate transporter Tpet_1706 107 COG1055 ArsB, Na+/H+ antiporter NhaD and related arsenite permeases Inorganic ion transport and metabolism 148270796 Common - transcriptional regulator, DeoR family Tpet_1675 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 148270498 Common - NADH dehydrogenase (quinone) Tpet_1368 196 COG1894 NuoF, NADH:ubiquinone oxidoreductase, NADH-binding (51 kD) subunit Energy production and conversion 148270400 Common - Diaminopimelate epimerase Tpet_1270 190 COG0253 DapF, Diaminopimelate epimerase Amino acid transport and metabolism 148269320 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Tpet_0175 219 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 148270026 Common - extracellular solute-binding protein, family 5 Tpet_0892 180 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148269596 Common - Protein-glutamate O-methyltransferase Tpet_0456 151 COG1352 CheR, Methylase of chemotaxis methyl-accepting proteins Cell motility and secretion / Signal transduction mechanisms 148270770 Common - RNA methyltransferase, TrmA family Tpet_1649 203 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 148270546 Common - flagellar hook-basal body complex subunit FliE Tpet_1417 95 COG1677 FliE, Flagellar hook-basal body protein Cell motility and secretion / Intracellular trafficking and secretion 148270839 Common - major facilitator superfamily MFS_1 Tpet_1718 50 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148270334 Common - diguanylate cyclase Tpet_1204 178 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 148270020 Common - metal dependent phosphohydrolase Tpet_0886 119 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 148270873 Nonpathogen - hypothetical protein Tpet_1756 1 None None None 148270632 Common - binding-protein-dependent transport systems inner membrane component Tpet_1508 224 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 148269562 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_0422 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270851 Common - Glu/Leu/Phe/Val dehydrogenase, C terminal Tpet_1731 173 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 148269219 Common - histidine kinase Tpet_0074 223 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148269616 Common aspA aspartate ammonia-lyase Tpet_0476 212 COG1027 AspA, Aspartate ammonia-lyase Amino acid transport and metabolism 148270601 Nonpathogen - hypothetical protein Tpet_1476 1 None None None 148270150 Common - GCN5-related N-acetyltransferase Tpet_1016 79 COG2153 ElaA, Predicted acyltransferase General function prediction only 148270215 Common - CRISPR-associated protein Cas5 family Tpet_1085 6 COG1688 COG1688, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 148269512 Common - putative alpha-isopropylmalate/homocitrate synthase family transferase Tpet_0368 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 148269526 Common - hypothetical protein Tpet_0384 33 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 148270532 Common - protein of unknown function DUF558 Tpet_1403 176 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 148269591 Common - Uncharacterized protein-like protein Tpet_0451 37 COG5011 COG5011, Uncharacterized protein conserved in bacteria Function unknown 148270269 Common - hypothetical protein Tpet_1139 13 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 148270297 Common - glycoside hydrolase family 2, sugar binding Tpet_1167 69 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 148269811 Common - Fe-S cluster domain protein Tpet_0675 78 COG2878 COG2878, Predicted NADH:ubiquinone oxidoreductase, subunit RnfB Energy production and conversion 148270684 Common - galactose-1-phosphate uridylyltransferase Tpet_1561 78 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 148270539 Common - hypothetical protein Tpet_1410 6 None None None 148270192 Common - protein of unknown function DUF322 Tpet_1059 26 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 148269456 Common - beta-lactamase domain protein Tpet_0311 38 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148269633 Common - oxidoreductase domain protein Tpet_0494 147 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 148270812 Common - major facilitator superfamily MFS_1 Tpet_1691 29 None None None 148269283 Common - 7-cyano-7-deazaguanine reductase Tpet_0138 97 COG0780 COG0780, Enzyme related to GTP cyclohydrolase I General function prediction only 148269966 Nonpathogen - hypothetical protein Tpet_0831 1 None None None 148269334 Common - threonyl-tRNA synthetase Tpet_0189 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148270246 Nonpathogen - putative metal dependent phosphohydrolase Tpet_1116 2 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 148270319 Common - major facilitator superfamily MFS_1 Tpet_1189 118 COG2271 UhpC, Sugar phosphate permease Carbohydrate transport and metabolism 148270921 Common - transcriptional regulator, PadR-like family Tpet_1805 24 COG1695 COG1695, Predicted transcriptional regulators Transcription 148269769 Common - Alpha-N-arabinofuranosidase Tpet_0633 29 COG3534 AbfA, Alpha-L-arabinofuranosidase Carbohydrate transport and metabolism 148269359 Common - carboxyl transferase Tpet_0214 218 COG4799 COG4799, Acetyl-CoA carboxylase, carboxyltransferase component (subunits alpha and beta) Lipid metabolism 148270397 Nonpathogen - glycoside hydrolase, family 12 Tpet_1267 5 None None None 148269641 Common - extracellular solute-binding protein, family 1 Tpet_0503 41 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 148269690 Common - putative aminopeptidase 1 Tpet_0553 44 COG1362 LAP4, Aspartyl aminopeptidase Amino acid transport and metabolism 148269879 Nonpathogen - hypothetical protein Tpet_0744 1 None None None 148269350 Common - Na+/Ca+ antiporter, CaCA family Tpet_0205 133 COG0530 ECM27, Ca2+/Na+ antiporter Inorganic ion transport and metabolism 148269843 Common - Glycine--tRNA ligase Tpet_0707 168 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 148269691 Common - alpha amylase, catalytic region Tpet_0554 167 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 148270310 Common - ATP synthase F1, gamma subunit Tpet_1180 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 148269830 Common - phosphodiesterase, MJ0936 family Tpet_0694 31 COG0622 COG0622, Predicted phosphoesterase General function prediction only 148270711 Common - Esterase/lipase-like protein Tpet_1589 66 COG0657 Aes, Esterase/lipase Lipid metabolism 148269156 Common - protein of unknown function DUF114 Tpet_0011 50 COG0616 SppA, Periplasmic serine proteases (ClpP class) Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 148270560 Common - PHP C-terminal domain protein Tpet_1431 11 COG0613 COG0613, Predicted metal-dependent phosphoesterases (PHP family) General function prediction only 148269598 Common - pseudouridine synthase, RluA family Tpet_0458 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 148269730 Common - transcriptional regulator, RpiR family Tpet_0593 89 COG1737 RpiR, Transcriptional regulators Transcription 148270746 Common - transcriptional regulator, SARP family Tpet_1624 21 COG3629 DnrI, DNA-binding transcriptional activator of the SARP family Signal transduction mechanisms 148270616 Nonpathogen - hypothetical protein Tpet_1492 1 None None None 148270472 Common - DNA primase Tpet_1342 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 148270130 Nonpathogen - HAD-superfamily hydrolase, subfamily IA, variant 1 Tpet_0996 11 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 148269976 Common - flagellar hook-associated protein FlgK Tpet_0841 122 COG1256 FlgK, Flagellar hook-associated protein Cell motility and secretion 148270574 Common - major facilitator superfamily MFS_1 Tpet_1445 187 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 148270354 Common - 16S rRNA processing protein RimM Tpet_1224 187 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 148269931 Common - pyruvate carboxylase subunit B Tpet_0796 155 COG5016 COG5016, Pyruvate/oxaloacetate carboxyltransferase Energy production and conversion 148270672 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_1548 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269531 Common - binding-protein-dependent transport systems inner membrane component Tpet_0389 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270300 Common - glycerophosphoryl diester phosphodiesterase Tpet_1170 141 COG0584 UgpQ, Glycerophosphoryl diester phosphodiesterase Energy production and conversion 148270370 Common - Radical SAM domain protein Tpet_1240 108 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 148269364 Common - S-layer domain protein Tpet_0219 132 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 148270710 Common - response regulator receiver protein Tpet_1588 188 COG2239 MgtE, Mg/Co/Ni transporter MgtE (contains CBS domain) Inorganic ion transport and metabolism 148269700 Common - iron-containing alcohol dehydrogenase Tpet_0563 171 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 148269853 Common - Zn-dependent hydrolase of the beta-lactamase fold-like protein Tpet_0717 105 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 148270508 Common - inositol monophosphatase Tpet_1378 213 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 148269495 Common - peptidase M23B Tpet_0350 83 COG3584 COG3584, Uncharacterized protein conserved in bacteria Function unknown 148270303 Common - CheC domain protein Tpet_1173 18 COG1406 COG1406, Predicted inhibitor of MCP methylation, homolog of CheC Cell motility and secretion 148270590 Common - Fe-S oxidoreductase-like protein Tpet_1461 10 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 148270309 Common - F0F1 ATP synthase subunit alpha Tpet_1179 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 148270203 Common argJ bifunctional ornithine acetyltransferase/N-acetylglutamate synthase protein Tpet_1070 167 COG1364 ArgJ, N-acetylglutamate synthase (N-acetylornithine aminotransferase) Amino acid transport and metabolism 148269796 Common - pseudouridine synthase Tpet_0660 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 148269171 Nonpathogen - hypothetical protein Tpet_0026 1 None None None 148270144 Common - UDP-N-acetylenolpyruvoylglucosamine reductase Tpet_1010 209 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 148269957 Common - basic membrane lipoprotein Tpet_0822 106 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 148270645 Common - phosphoribosylamine--glycine ligase Tpet_1521 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 148270856 Nonpathogen - hypothetical protein Tpet_1737 1 None None None 148269732 Common - TRAP dicarboxylate transporter, DctM subunit Tpet_0595 134 COG1593 DctQ, TRAP-type C4-dicarboxylate transport system, large permease component Carbohydrate transport and metabolism 148270552 Common - response regulator receiver protein Tpet_1423 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148269390 Common - DNA polymerase III, subunits gamma and tau Tpet_0245 249 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 148269447 Nonpathogen - WD-40 repeat protein Tpet_0302 1 COG2319 COG2319, FOG: WD40 repeat General function prediction only 148269176 Common - galactose-1-phosphate uridylyltransferase Tpet_0031 78 COG1085 GalT, Galactose-1-phosphate uridylyltransferase Energy production and conversion 148269721 Common pyrC dihydroorotase Tpet_0584 206 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 148270561 Common - glutamyl-tRNA synthetase Tpet_1432 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 148270781 Common - DNA gyrase, A subunit Tpet_1660 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 148270107 Common - transposase, IS605 OrfB family Tpet_0973 63 COG0675 COG0675, Transposase and inactivated derivatives DNA replication, recombination, and repair 148270068 Common - hypothetical protein Tpet_0934 11 None None None 148270121 Common - hypothetical protein Tpet_0987 139 COG1561 COG1561, Uncharacterized stress-induced protein Function unknown 148269452 Common - glycosyl transferase, group 1 Tpet_0307 205 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148270426 Common - ribosomal protein S19 Tpet_1296 245 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 148270129 Common - metal dependent phosphohydrolase Tpet_0995 123 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 148270706 Common - 2-oxoacid ferredoxin oxidoreductase subunit beta Tpet_1584 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 148269613 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit Tpet_0473 210 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 148270328 Common - Tetratricopeptide TPR_2 repeat protein Tpet_1198 4 COG1373 COG1373, Predicted ATPase (AAA+ superfamily) General function prediction only 148270211 Common - CRISPR-associated protein Cas2 Tpet_1081 48 COG1343 COG1343, Uncharacterized protein predicted to be involved in DNA repair DNA replication, recombination, and repair 148270288 Common - ATP-dependent protease La Tpet_1158 218 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 148269935 Common - ABC transporter related Tpet_0800 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 148270276 Common - nicotinate-nucleotide pyrophosphorylase Tpet_1146 204 COG0157 NadC, Nicotinate-nucleotide pyrophosphorylase Coenzyme metabolism 148269459 Common - single-strand binding protein Tpet_0314 211 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 148270523 Common - Methyltransferase type 11 Tpet_1394 180 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148270500 Common - Stage II sporulation E family protein Tpet_1370 11 COG2208 RsbU, Serine phosphatase RsbU, regulator of sigma subunit Signal transduction mechanisms / Transcription 148270031 Nonpathogen - hypothetical protein Tpet_0897 1 None None None 148269148 Common - Radical SAM domain protein Tpet_0003 45 COG1313 PflX, Uncharacterized Fe-S protein PflX, homolog of pyruvate formate lyase activating proteins General function prediction only 148270665 Common - transcriptional regulator, RpiR family Tpet_1541 129 COG1737 RpiR, Transcriptional regulators Transcription 148270149 Common - DNA mismatch repair protein Tpet_1015 206 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 148270627 Nonpathogen - hypothetical protein Tpet_1503 2 None None None 148270517 Common - alanyl-tRNA synthetase Tpet_1387 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148270382 Nonpathogen - flagellar L-ring protein Tpet_1252 17 COG2063 FlgH, Flagellar basal body L-ring protein Cell motility and secretion 148269729 Common - D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding Tpet_0592 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 148270578 Nonpathogen - hypothetical protein Tpet_1449 2 None None None 148270413 Common - protein of unknown function UPF0054 Tpet_1283 202 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 148269461 Common - iron dependent repressor Tpet_0316 25 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 148270375 Common - metal dependent phosphohydrolase Tpet_1245 88 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 148269860 Common - protein of unknown function DUF147 Tpet_0724 28 COG1623 COG1623, Predicted nucleic-acid-binding protein (contains the HHH domain) General function prediction only 148269608 Common - preprotein translocase, SecE subunit Tpet_0468 26 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 148270061 Common - septum site-determining protein MinD Tpet_0927 180 COG2894 MinD, Septum formation inhibitor-activating ATPase Cell division and chromosome partitioning 148269307 Common - regulatory protein GntR, HTH Tpet_0162 28 COG1725 COG1725, Predicted transcriptional regulators Transcription 148269300 Common - hypothetical protein Tpet_0155 26 None None None 148270654 Common - translation-associated GTPase Tpet_1530 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 148269296 Common - transposase IS200-family protein Tpet_0151 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 148269809 Common - carbon storage regulator, CsrA Tpet_0673 84 COG1551 CsrA, Carbon storage regulator (could also regulate swarming and quorum sensing) Signal transduction mechanisms 148269263 Common - extracellular solute-binding protein, family 1 Tpet_0118 117 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148269568 Common - tryptophanyl-tRNA synthetase Tpet_0428 249 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148270844 Common - hypothetical protein Tpet_1723 3 None None None 148269436 Nonpathogen - hypothetical protein Tpet_0291 2 None None None 148270817 Common - conserved hypothetical protein 730 Tpet_1696 85 COG1611 COG1611, Predicted Rossmann fold nucleotide-binding protein General function prediction only 148270493 Common - glycerol-3-phosphate responsive antiterminator Tpet_1363 26 COG1954 GlpP, Glycerol-3-phosphate responsive antiterminator (mRNA-binding) Transcription 148269970 Nonpathogen - hypothetical protein Tpet_0835 1 None None None 148269321 Common - ubiquinone/menaquinone biosynthesis methyltransferase Tpet_0176 228 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 148269824 Common - UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate--D-alanyl-D-alanyl ligase Tpet_0688 208 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 148270172 Common - aldo/keto reductase Tpet_1038 206 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 148269204 Common - glutaredoxin-like domain protein Tpet_0059 83 COG3634 AhpF, Alkyl hydroperoxide reductase, large subunit Posttranslational modification, protein turnover, chaperones 148269328 Nonpathogen - hypothetical protein Tpet_0183 1 None None None 148270054 Common - Radical SAM domain protein Tpet_0920 14 COG1856 COG1856, Uncharacterized homolog of biotin synthetase Function unknown 148270224 Common - CRISPR-associated RAMP protein, Csm4 family Tpet_1094 11 COG1567 COG1567, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 148270002 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_0867 249 COG4608 AppF, ABC-type oligopeptide transport system, ATPase component Amino acid transport and metabolism 148270247 Nonpathogen - hypothetical protein Tpet_1117 2 COG2245 COG2245, Predicted membrane protein Function unknown 148270268 Common - pyrimidine-nucleoside phosphorylase Tpet_1138 124 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 148269787 Common - fructose-1,6-bisphosphate aldolase, class II Tpet_0651 178 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 148270762 Common - Radical SAM domain protein Tpet_1640 144 COG1243 ELP3, Histone acetyltransferase Transcription / Chromatin structure and dynamics 148270484 Common - initiation factor 2B related Tpet_1354 35 COG1184 GCD2, Translation initiation factor 2B subunit, eIF-2B alpha/beta/delta family Translation, ribosomal structure and biogenesis 148270256 Common - histidine kinase Tpet_1126 88 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 148269847 Common - glycine dehydrogenase subunit 1 Tpet_0711 172 COG0403 GcvP, Glycine cleavage system protein P (pyridoxal-binding), N-terminal domain Amino acid transport and metabolism 148269681 Common - chaperone protein DnaK Tpet_0544 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 148269525 Common - cation diffusion facilitator family transporter Tpet_0383 206 COG1230 CzcD, Co/Zn/Cd efflux system component Inorganic ion transport and metabolism 148269406 Nonpathogen - hypothetical protein Tpet_0261 4 None None None 148270196 Common - ComEC/Rec2-related protein Tpet_1063 24 COG0658 ComEC, Predicted membrane metal-binding protein General function prediction only 148270311 Common - F0F1 ATP synthase subunit beta Tpet_1181 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 148269699 Nonpathogen - hypothetical protein Tpet_0562 1 None None None 148270690 Common mgsA methylglyoxal synthase Tpet_1568 88 COG1803 MgsA, Methylglyoxal synthase Carbohydrate transport and metabolism 148270261 Common - peptidase M23B Tpet_1131 128 COG0739 NlpD, Membrane proteins related to metalloendopeptidases Cell envelope biogenesis, outer membrane 148270885 Common - type III restriction enzyme, res subunit Tpet_1769 132 COG1061 SSL2, DNA or RNA helicases of superfamily II Transcription / DNA replication, recombination, and repair 148269944 Common - ABC transporter related Tpet_0809 249 COG1129 MglA, ABC-type sugar transport system, ATPase component Carbohydrate transport and metabolism 148270633 Common - phosphate ABC transporter, inner membrane subunit PstA Tpet_1509 226 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 148270728 Common - ABC transporter related Tpet_1606 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 148269355 Common - cysteinyl-tRNA synthetase Tpet_0210 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148270187 Common - Formate--tetrahydrofolate ligase Tpet_1054 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 148269502 Common - hypothetical protein Tpet_0357 2 COG0586 DedA, Uncharacterized membrane-associated protein Function unknown 148270824 Common - peptidase M42 family protein Tpet_1703 87 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 148269348 Common - peptidase U62, modulator of DNA gyrase Tpet_0203 169 COG0312 TldD, Predicted Zn-dependent proteases and their inactivated homologs General function prediction only 148269672 Common - nitroreductase Tpet_0534 103 COG0778 NfnB, Nitroreductase Energy production and conversion 148269754 Common - gamma-glutamyl kinase Tpet_0618 192 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 148270775 Common - potassium uptake protein, TrkH family Tpet_1654 155 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 148270156 Common - hypothetical protein Tpet_1022 45 COG5495 COG5495, Uncharacterized conserved protein Function unknown 148269679 Common - Propanediol utilization protein Tpet_0542 36 COG4869 PduL, Propanediol utilization protein Secondary metabolites biosynthesis, transport, and catabolism 148270894 Common - alpha-2-macroglobulin domain protein Tpet_1778 76 COG2373 COG2373, Large extracellular alpha-helical protein General function prediction only 148269425 Common - Cof-like hydrolase Tpet_0280 130 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 148269162 Common - flagellar biosynthetic protein FliR Tpet_0017 93 COG1684 FliR, Flagellar biosynthesis pathway, component FliR Cell motility and secretion / Intracellular trafficking and secretion 148269577 Common - ABC transporter related Tpet_0437 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 148269668 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Tpet_0530 242 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 148269224 Common - GTP-binding protein, HSR1-related Tpet_0079 25 COG1161 COG1161, Predicted GTPases General function prediction only 148269867 Common - conserved hypothetical protein 245 Tpet_0731 70 COG0390 COG0390, ABC-type uncharacterized transport system, permease component General function prediction only 148270233 Common - Chromate transporter Tpet_1103 81 COG2059 ChrA, Chromate transport protein ChrA Inorganic ion transport and metabolism 148269580 Common - excinuclease ABC, A subunit Tpet_0440 246 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 148270716 Common - phage shock protein C, PspC Tpet_1594 51 COG1983 PspC, Putative stress-responsive transcriptional regulator Transcription / Signal transduction mechanisms 148270100 Common - extracellular solute-binding protein, family 1 Tpet_0966 105 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 148269573 Common - protein of unknown function DUF59 Tpet_0433 157 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 148269415 Nonpathogen - hypothetical protein Tpet_0270 4 None None None 148270301 Common - alkylhydroperoxidase like protein, AhpD family Tpet_1171 59 COG0599 COG0599, Uncharacterized homolog of gamma-carboxymuconolactone decarboxylase subunit Function unknown 148269977 Common - flagellar hook-associated protein 3 Tpet_0842 90 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 148270478 Common - small GTP-binding protein Tpet_1348 238 COG1160 COG1160, Predicted GTPases General function prediction only 148269550 Common - flagellar export protein FliJ Tpet_0410 3 COG2882 FliJ, Flagellar biosynthesis chaperone Cell motility and secretion / Intracellular trafficking and secretion / Posttranslational modification, protein turnover, chaperones 148269985 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_0850 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269703 Common - Outer membrane protein-like protein Tpet_0566 4 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 148269883 Common - protein of unknown function DUF161 Tpet_0748 71 COG1284 COG1284, Uncharacterized conserved protein Function unknown 148269969 Nonpathogen - hypothetical protein Tpet_0834 1 None None None 148269971 Common - type II and III secretion system protein Tpet_0836 143 COG4796 HofQ, Type II secretory pathway, component HofQ Intracellular trafficking and secretion 148270754 Nonpathogen - hypothetical protein Tpet_1632 1 None None None 148269881 Common - Homing endonuclease, LAGLIDADG/HNH Tpet_0746 3 None None None 148270306 Common - ATP synthase F0, C subunit Tpet_1176 7 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 148269693 Common - apurinic endonuclease Apn1 Tpet_0556 100 COG0648 Nfo, Endonuclease IV DNA replication, recombination, and repair 148270398 Nonpathogen - glycoside hydrolase, family 12 Tpet_1268 5 None None None 148270678 Common - Arabinogalactan endo-1,4-beta-galactosidase Tpet_1555 21 COG3867 COG3867, Arabinogalactan endo-1,4-beta-galactosidase Carbohydrate transport and metabolism 148270759 Nonpathogen - hypothetical protein Tpet_1637 1 COG1863 MnhE, Multisubunit Na+/H+ antiporter, MnhE subunit Inorganic ion transport and metabolism 148269497 Nonpathogen - hypothetical protein Tpet_0352 3 None None None 148269520 Common - ABC transporter related Tpet_0376 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148270473 Common - RNA polymerase, sigma 70 subunit, RpoD family Tpet_1343 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 148269825 Common - phospho-N-acetylmuramoyl-pentapeptide-transferase Tpet_0689 225 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 148269871 Common - periplasmic binding protein Tpet_0735 89 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 148270741 Nonpathogen - hypothetical protein Tpet_1619 1 None None None 148269515 Common - acetolactate synthase, small subunit Tpet_0371 191 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 148269674 Common - anaerobic ribonucleoside triphosphate reductase Tpet_0536 99 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 148270904 Common - LemA family protein Tpet_1788 132 COG1704 LemA, Uncharacterized conserved protein Function unknown 148269800 Common - protein of unknown function DUF47 Tpet_0664 37 COG1392 COG1392, Phosphate transport regulator (distant homolog of PhoU) Inorganic ion transport and metabolism 148270689 Nonpathogen - putative regulatory protein, FmdB family Tpet_1567 3 COG1241 MCM2, Predicted ATPase involved in replication control, Cdc46/Mcm family DNA replication, recombination, and repair 148270458 Common - cob(I)yrinic acid a,c-diamide adenosyltransferase Tpet_1328 141 COG2109 BtuR, ATP:corrinoid adenosyltransferase Coenzyme metabolism 148269275 Common - malonyl CoA-acyl carrier protein transacylase Tpet_0130 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 148270503 Common - Myo-inositol-1-phosphate synthase Tpet_1373 61 COG1260 INO1, Myo-inositol-1-phosphate synthase Lipid metabolism 148270836 Common - phosphoribosyl-ATP pyrophosphohydrolase Tpet_1715 213 COG0139 HisI, Phosphoribosyl-AMP cyclohydrolase Amino acid transport and metabolism 148269317 Common - glycosyl transferase, family 2 Tpet_0172 159 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 148270482 Common - anti-sigma-factor antagonist Tpet_1352 84 COG1366 SpoIIAA, Anti-anti-sigma regulatory factor (antagonist of anti-sigma factor) Signal transduction mechanisms 148270405 Common - diaminopimelate decarboxylase Tpet_1275 216 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 148270266 Common - two component transcriptional regulator, winged helix family Tpet_1136 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148270294 Common - ribosomal 5S rRNA E-loop binding protein Ctc/L25/TL5 Tpet_1164 173 COG1825 RplY, Ribosomal protein L25 (general stress protein Ctc) Translation, ribosomal structure and biogenesis 148270905 Common - ribokinase Tpet_1789 215 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 148269768 Nonpathogen - hypothetical protein Tpet_0632 2 None None None 148269366 Common - Uroporphyrin-III C/tetrapyrrole (Corrin/Porphyrin) methyltransferase Tpet_0221 216 COG0313 COG0313, Predicted methyltransferases General function prediction only 148269814 Common - electron transport complex, RnfABCDGE type, G subunit Tpet_0678 6 COG4659 RnfG, Predicted NADH:ubiquinone oxidoreductase, subunit RnfG Energy production and conversion 148270009 Common - FeoA family protein Tpet_0874 62 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 148269559 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_0419 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269780 Common - binding-protein-dependent transport systems inner membrane component Tpet_0644 206 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148270584 Common - ABC-2 type transporter Tpet_1455 78 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 148270358 Common - acylphosphatase Tpet_1228 158 COG1254 AcyP, Acylphosphatases Energy production and conversion 148269761 Common - ABC transporter related Tpet_0625 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 148270446 Common rpmJ 50S ribosomal protein L36 Tpet_1316 120 COG0257 RpmJ, Ribosomal protein L36 Translation, ribosomal structure and biogenesis 148270353 Common - tRNA (guanine-N1)-methyltransferase Tpet_1223 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 148270739 Common - Ferroxidase Tpet_1617 85 COG1528 Ftn, Ferritin-like protein Inorganic ion transport and metabolism 148269594 Common - hypothetical protein Tpet_0454 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 148270713 Common - hypothetical protein Tpet_1591 11 COG0010 SpeB, Arginase/agmatinase/formimionoglutamate hydrolase, arginase family Amino acid transport and metabolism 148269622 Common - 6-phosphogluconate dehydrogenase Tpet_0482 184 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 148270465 Nonpathogen - Cupin 2, conserved barrel domain protein Tpet_1335 23 COG1917 COG1917, Uncharacterized conserved protein, contains double-stranded beta-helix domain Function unknown 148270519 Common - Hsp33 protein Tpet_1389 130 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 148269994 Common - Transcriptional regulator IclR-like protein Tpet_0859 123 COG1414 IclR, Transcriptional regulator Transcription 148269288 Common - hypothetical protein Tpet_0143 23 COG3461 COG3461, Uncharacterized conserved protein Function unknown 148270216 Common - CRISPR-associated regulatory protein, DevR family Tpet_1086 8 None None None 148269857 Common - binding-protein-dependent transport systems inner membrane component Tpet_0721 178 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 148270029 Common - oligopeptide/dipeptide ABC transporter, ATPase subunit Tpet_0895 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270795 Common - protein of unknown function DUF1362 Tpet_1674 11 COG4288 COG4288, Uncharacterized protein conserved in bacteria Function unknown 148269912 Common - glucosamine--fructose-6-phosphate aminotransferase, isomerizing Tpet_0777 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 148269555 Common - chaperonin GroEL Tpet_0415 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 148269534 Nonpathogen - hypothetical protein Tpet_0392 2 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 148269232 Nonpathogen - hypothetical protein Tpet_0087 1 None None None 148269312 Common - major facilitator superfamily MFS_1 Tpet_0167 37 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148269835 Common - D-cysteine desulfhydrase Tpet_0699 84 COG2515 Acd, 1-aminocyclopropane-1-carboxylate deaminase Amino acid transport and metabolism 148269916 Common - putative regulatory protein, FmdB family Tpet_0781 56 COG2331 COG2331, Uncharacterized protein conserved in bacteria Function unknown 148270846 Common - Esterase/lipase-like protein Tpet_1725 73 COG1647 COG1647, Esterase/lipase General function prediction only 148269772 Common - extracellular solute-binding protein, family 1 Tpet_0636 68 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148269618 Common - hypothetical protein Tpet_0478 19 COG3875 COG3875, Uncharacterized conserved protein Function unknown 148269648 Common - protein of unknown function DUF523 Tpet_0510 64 COG1683 COG1683, Uncharacterized conserved protein Function unknown 148270182 Common - excinuclease ABC subunit B Tpet_1049 225 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 148269242 Common - MiaB-like tRNA modifying enzyme Tpet_0097 233 COG0621 MiaB, 2-methylthioadenine synthetase Translation, ribosomal structure and biogenesis 148270022 Nonpathogen - hypothetical protein Tpet_0888 1 None None None 148269294 Common - protein of unknown function DUF82 Tpet_0149 43 COG1656 COG1656, Uncharacterized conserved protein Function unknown 148270088 Common - extracellular solute-binding protein, family 1 Tpet_0954 128 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148270363 Common - deoxyribose-phosphate aldolase Tpet_1233 136 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 148269712 Common - 3-phosphoshikimate 1-carboxyvinyltransferase Tpet_0575 231 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 148269923 Common - tryptophan synthase, alpha subunit Tpet_0788 217 COG0159 TrpA, Tryptophan synthase alpha chain Amino acid transport and metabolism 148270083 Nonpathogen - hypothetical protein Tpet_0949 1 None None None 148269900 Common - protein of unknown function DUF151 Tpet_0765 75 COG1259 COG1259, Uncharacterized conserved protein Function unknown 148270534 Common - Ornithine carbamoyltransferase Tpet_1405 226 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 148269892 Common - leucyl-tRNA synthetase Tpet_0757 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148269382 Nonpathogen - hypothetical protein Tpet_0237 3 None None None 148269968 Nonpathogen - hypothetical protein Tpet_0833 1 None None None 148269476 Common - putative manganese-dependent inorganic pyrophosphatase Tpet_0331 60 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 148270861 Common - aldo/keto reductase Tpet_1743 204 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 148269281 Common - ABC transporter related Tpet_0136 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148270428 Common - ribosomal protein S3 Tpet_1298 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 148270643 Nonpathogen - hypothetical protein Tpet_1519 2 None None None 148270875 Common - SirA family protein Tpet_1758 56 COG0425 SirA, Predicted redox protein, regulator of disulfide bond formation Posttranslational modification, protein turnover, chaperones 148270072 Common recA recombinase A Tpet_0938 243 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 148269665 Common - ROK family protein Tpet_0527 55 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 148269250 Common - phenylalanyl-tRNA synthetase, beta subunit Tpet_0105 249 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 148270732 Common - Extracellular ligand-binding receptor Tpet_1610 152 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 148269548 Common - prolyl-tRNA synthetase Tpet_0408 249 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148269184 Common - thiamine pyrophosphokinase Tpet_0039 29 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 148270153 Common - amidohydrolase Tpet_1019 75 COG1228 HutI, Imidazolonepropionase and related amidohydrolases Secondary metabolites biosynthesis, transport, and catabolism 148269837 Common - RNA-binding S4 domain protein Tpet_0701 27 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 148270286 Common - nuclease SbcCD, D subunit Tpet_1156 127 COG0420 SbcD, DNA repair exonuclease DNA replication, recombination, and repair 148269962 Common - nicotinate (nicotinamide) nucleotide adenylyltransferase Tpet_0827 185 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 148270877 Common - DsrE family protein Tpet_1760 23 COG1553 DsrE, Uncharacterized conserved protein involved in intracellular sulfur reduction Inorganic ion transport and metabolism 148269336 Common - hypothetical protein Tpet_0191 5 COG2015 COG2015, Alkyl sulfatase and related hydrolases Secondary metabolites biosynthesis, transport, and catabolism 148270525 Common coaE dephospho-CoA kinase Tpet_1396 147 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 148269727 Nonpathogen - hypothetical protein Tpet_0590 1 None None None 148269178 Common - beta-lactamase domain protein Tpet_0033 32 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 148269196 Common - cation diffusion facilitator family transporter Tpet_0051 215 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 148270384 Nonpathogen - hypothetical protein Tpet_1254 4 None None None 148270502 Common - NADH:ubiquinone oxidoreductase 24 kD subunit-like protein Tpet_1372 4 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 148269305 Common - GTP-binding protein, HSR1-related Tpet_0160 96 COG1161 COG1161, Predicted GTPases General function prediction only 148269741 Common - aldo/keto reductase Tpet_0604 202 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 148270722 Common - extracellular solute-binding protein, family 5 Tpet_1600 210 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 148269663 Common - FAD-dependent pyridine nucleotide-disulphide oxidoreductase Tpet_0525 244 COG1251 NirB, NAD(P)H-nitrite reductase Energy production and conversion 148269449 Nonpathogen - DNA polymerase, beta domain protein region Tpet_0304 2 COG1669 COG1669, Predicted nucleotidyltransferases General function prediction only 148270629 Common - hypothetical protein Tpet_1505 14 None None None 148270788 Common - pantoate--beta-alanine ligase Tpet_1667 182 COG0414 PanC, Panthothenate synthetase Coenzyme metabolism 148270652 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase Tpet_1528 170 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 148270136 Common - transcription elongation factor GreA Tpet_1002 203 COG0782 GreA, Transcription elongation factor Transcription 148270541 Common - cysteine desulfurase, SufS subfamily Tpet_1412 237 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 148269818 Nonpathogen - hypothetical protein Tpet_0682 1 None None None 148269869 Common - ABC transporter related Tpet_0733 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 148270868 Common - phosphoadenosine phosphosulfate reductase Tpet_1751 37 COG0175 CysH, 3'-phosphoadenosine 5'-phosphosulfate sulfotransferase (PAPS reductase)/FAD synthetase and related enzymes Amino acid transport and metabolism / Coenzyme metabolism 148270249 Common - protein of unknown function DUF218 Tpet_1119 113 COG1434 COG1434, Uncharacterized conserved protein Function unknown 148270356 Common - ribosomal protein S16 Tpet_1226 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 148269654 Common - CMP/dCMP deaminase, zinc-binding Tpet_0516 112 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 148269517 Common - aspartate kinase Tpet_0373 237 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 148269465 Common - Monosaccharide-transporting ATPase Tpet_0320 158 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148270039 Common - thiamine pyrophosphate enzyme domain protein TPP-binding Tpet_0905 118 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 148270049 Common - cyclase family protein Tpet_0915 63 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 148270166 Common - purine nucleoside phosphorylase Tpet_1032 160 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 148269440 Common - Mannosyl-glycoprotein endo-beta-N-acetylglucosamidase Tpet_0295 56 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 148270756 Nonpathogen - subunit of the Multisubunit Na+/H+ antiporter-like protein Tpet_1634 3 COG1563 COG1563, Predicted subunit of the Multisubunit Na+/H+ antiporter Inorganic ion transport and metabolism 148270123 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase Tpet_0989 211 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 148270424 Common - Ribosomal protein L25/L23 Tpet_1294 219 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 148269341 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Tpet_0196 22 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 148270530 Common - NUDIX hydrolase Tpet_1401 7 COG4112 COG4112, Predicted phosphoesterase (MutT family) General function prediction only 148270142 Nonpathogen - hypothetical protein Tpet_1008 1 None None None 148270635 Common - phosphate uptake regulator, PhoU Tpet_1511 198 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 148269392 Nonpathogen - Tartrate dehydratase beta subunit/Fumarate hydratase class I C-terminal domain-like protein Tpet_0247 2 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 148270095 Nonpathogen - hypothetical protein Tpet_0961 3 None None None 148270469 Common - membrane protein-like protein Tpet_1339 23 COG3601 COG3601, Predicted membrane protein Function unknown 148270151 Nonpathogen - hypothetical protein Tpet_1017 6 COG5316 COG5316, Uncharacterized conserved protein Function unknown 148270854 Nonpathogen - hypothetical protein Tpet_1735 1 None None None 148270282 Common - ferredoxin--NADP(+) reductase subunit alpha Tpet_1152 86 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 148270015 Common - peptidase M24 Tpet_0881 247 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 148269646 Common - Alcohol dehydrogenase GroES domain protein Tpet_0508 205 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 148269442 Common - glycosyl transferase, group 1 Tpet_0297 162 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 148270279 Common pyrB bifunctional aspartate carbamoyltransferase catalytic subunit/aspartate carbamoyltransferase regulatory subunit Tpet_1149 236 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 148269802 Common - DNA topoisomerase I Tpet_0666 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 148269412 Nonpathogen - protein of unknown function DUF123 Tpet_0267 24 COG1833 COG1833, Uncharacterized conserved protein Function unknown 148270896 Common - phage integrase family protein Tpet_1780 227 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 148270180 Common - thiamine pyrophosphate enzyme domain protein TPP-binding Tpet_1047 109 COG1013 PorB, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, beta subunit Energy production and conversion 148270599 Nonpathogen - protein of unknown function UPF0150 Tpet_1472 7 None None None 148270251 Nonpathogen - FlhB domain protein Tpet_1121 3 COG2257 COG2257, Uncharacterized homolog of the cytoplasmic domain of flagellar protein FhlB Function unknown 148270342 Common - transcriptional regulator, Fis family Tpet_1212 128 COG1221 PspF, Transcriptional regulators containing an AAA-type ATPase domain and a DNA-binding domain Transcription / Signal transduction mechanisms 148269342 Nonpathogen - hypothetical protein Tpet_0197 1 None None None 148270697 Common - GCN5-related N-acetyltransferase Tpet_1575 21 COG0456 RimI, Acetyltransferases General function prediction only 148269409 Common - hydrolase, TatD family Tpet_0264 237 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 148269706 Common - protein of unknown function DUF214 Tpet_0569 200 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 148269888 Common - S-adenosyl-L-homocysteine hydrolase Tpet_0753 178 COG0499 SAM1, S-adenosylhomocysteine hydrolase Coenzyme metabolism 148269849 Common - glycine cleavage system T protein Tpet_0713 179 COG0404 GcvT, Glycine cleavage system T protein (aminomethyltransferase) Amino acid transport and metabolism 148270394 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase Tpet_1264 110 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 148269504 Common - magnesium and cobalt transport protein CorA Tpet_0359 179 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 148270229 Common - CRISPR-associated protein Cas6 Tpet_1099 29 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 148269499 Common - Conserved protein/domain typically associated with flavoprotein oxygenase DIM6/NTAB family-like protein Tpet_0354 14 COG1853 COG1853, Conserved protein/domain typically associated with flavoprotein oxygenases, DIM6/NTAB family General function prediction only 148270336 Common - hypothetical protein Tpet_1206 6 COG0778 NfnB, Nitroreductase Energy production and conversion 148270671 Common - binding-protein-dependent transport systems inner membrane component Tpet_1547 219 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270586 Common - Radical SAM domain protein Tpet_1457 105 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 148269611 Common thyX FAD-dependent thymidylate synthase Tpet_0471 75 COG1351 THY1, Predicted alternative thymidylate synthase Nucleotide transport and metabolism 148269575 Common - binding-protein-dependent transport systems inner membrane component Tpet_0435 148 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 148269995 Common - glucuronate isomerase Tpet_0860 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 148270701 Common - metal dependent phosphohydrolase Tpet_1579 182 COG2206 COG2206, HD-GYP domain Signal transduction mechanisms 148269698 Common - diacylglycerol kinase, catalytic region Tpet_0561 105 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 148269463 Common - Uncharacterized FAD-dependent dehydrogenase-like protein Tpet_0318 44 COG2509 COG2509, Uncharacterized FAD-dependent dehydrogenases General function prediction only 148270231 Common - Dinitrogenase iron-molybdenum cofactor biosynthesis protein Tpet_1101 41 COG1433 COG1433, Uncharacterized conserved protein Function unknown 148269753 Common - putative translaldolase Tpet_0617 167 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 148270486 Common - Domain of unknown function DUF1957 Tpet_1356 35 COG1543 COG1543, Uncharacterized conserved protein Function unknown 148270591 Nonpathogen - protein of unknown function UPF0150 Tpet_1463 1 COG1598 COG1598, Uncharacterized conserved protein Function unknown 148269399 Common - OmpA/MotB domain protein Tpet_0254 84 COG1360 MotB, Flagellar motor protein Cell motility and secretion 148269413 Common - hydrolase of the metallo-beta-lactamase superfamily-like protein Tpet_0268 10 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 148269326 Common - tRNA methyltransferase complex GCD14 subunit Tpet_0181 66 COG2519 GCD14, tRNA(1-methyladenosine) methyltransferase and related methyltransferases Translation, ribosomal structure and biogenesis 148270581 Nonpathogen - hypothetical protein Tpet_1452 1 None None None 148270222 Nonpathogen - hypothetical protein Tpet_1092 1 None None None 148270056 Common - glutamyl-tRNA synthetase Tpet_0922 249 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 148270460 Nonpathogen rpmH 50S ribosomal protein L34 Tpet_1330 4 None None None 148270174 Nonpathogen - hypothetical protein Tpet_1040 1 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 148270658 Nonpathogen - extracellular solute-binding protein, family 1 Tpet_1534 9 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 148270764 Common - phosphodiesterase Tpet_1642 63 COG0622 COG0622, Predicted phosphoesterase General function prediction only 148270258 Common - ABC transporter related Tpet_1128 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 148269589 Nonpathogen - putative diguanylate cyclase Tpet_0449 1 COG2199 COG2199, FOG: GGDEF domain Signal transduction mechanisms 148270037 Common - CrcB protein Tpet_0903 178 COG0239 CrcB, Integral membrane protein possibly involved in chromosome condensation Cell division and chromosome partitioning 148270649 Common - phosphoribosylformylglycinamidine synthase II Tpet_1525 234 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 148270185 Nonpathogen - protein of unknown function DUF322 Tpet_1052 4 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 148269408 Common - DegT/DnrJ/EryC1/StrS aminotransferase Tpet_0263 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 148269485 Common - pyrroline-5-carboxylate reductase Tpet_0340 214 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 148269890 Nonpathogen - hypothetical protein Tpet_0755 4 None None None 148270040 Common - pyruvate flavodoxin/ferredoxin oxidoreductase domain protein Tpet_0906 116 COG0674 PorA, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, alpha subunit Energy production and conversion 148270511 Common - daunorubicin resistance ABC transporter ATPase subunit Tpet_1381 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 148269603 Common - ribosomal protein L7/L12 Tpet_0463 215 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 148270367 Common - Heptaprenyl diphosphate synthase component I Tpet_1237 20 COG4769 COG4769, Predicted membrane protein Function unknown 148270238 Common - HflC protein Tpet_1108 217 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 148269457 Nonpathogen - Uncharacterized protein-like protein Tpet_0312 3 COG3906 COG3906, Uncharacterized protein conserved in bacteria Function unknown 148269942 Common - Radical SAM domain protein Tpet_0807 105 COG1533 SplB, DNA repair photolyase DNA replication, recombination, and repair 148269937 Common - ferric uptake regulator, Fur family Tpet_0802 130 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 148269566 Common - putative transcriptional regulator Tpet_0426 102 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 148269168 Common - CheC, inhibitor of MCP methylation Tpet_0023 33 COG1776 CheC, Chemotaxis protein CheC, inhibitor of MCP methylation Cell motility and secretion / Signal transduction mechanisms 148269450 Nonpathogen - ATPase Tpet_0305 3 COG4928 COG4928, Predicted P-loop ATPase General function prediction only 148270571 Common - Rieske (2Fe-2S) domain protein Tpet_1442 77 COG4638 HcaE, Phenylpropionate dioxygenase and related ring-hydroxylating dioxygenases, large terminal subunit Inorganic ion transport and metabolism / General function prediction only 148270505 Common - CDP-alcohol phosphatidyltransferase Tpet_1375 58 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 148270863 Common - putative PAS/PAC sensor protein Tpet_1746 25 COG2461 COG2461, Uncharacterized conserved protein Function unknown 148270889 Nonpathogen - hypothetical protein Tpet_1773 1 None None None 148269277 Common - protein of unknown function DUF1611 Tpet_0132 39 COG3367 COG3367, Uncharacterized conserved protein Function unknown 148270536 Common - spermidine/putrescine ABC transporter ATPase subunit Tpet_1407 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 148270840 Common - glutaredoxin-like protein, YruB-family Tpet_1719 89 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 148270298 Common - GTP-binding protein LepA Tpet_1168 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 148269766 Common - Aldose 1-epimerase Tpet_0630 102 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 148269368 Common - methyltransferase GidB Tpet_0223 197 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 148270292 Common - UDP-N-acetylglucosamine pyrophosphorylase Tpet_1162 239 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 148269907 Common - hypothetical protein Tpet_0772 5 None None None 148269816 Common - electron transport complex, RnfABCDGE type, C subunit Tpet_0680 97 COG4656 RnfC, Predicted NADH:ubiquinone oxidoreductase, subunit RnfC Energy production and conversion 148269270 Common - CTP synthetase Tpet_0125 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 148269980 Common - transport system permease protein Tpet_0845 193 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 148269310 Common - protein of unknown function DUF74 Tpet_0165 106 COG0393 COG0393, Uncharacterized conserved protein Function unknown 148269315 Common - flagellin domain protein Tpet_0170 124 COG1344 FlgL, Flagellin and related hook-associated proteins Cell motility and secretion 148269339 Common - protein of unknown function DUF342 Tpet_0194 36 COG1315 COG1315, Predicted polymerase, most proteins contain PALM domain, HD hydrolase domain and Zn-ribbon domain DNA replication, recombination, and repair 148269765 Common - L-ribulose-5-phosphate 4-epimerase Tpet_0629 167 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 148270462 Common - protein of unknown function DUF37 Tpet_1332 187 COG0759 COG0759, Uncharacterized conserved protein Function unknown 148269187 Common - Protein of unknown function DUF1867 Tpet_0042 20 COG1751 COG1751, Uncharacterized conserved protein Function unknown 148269387 Common - Phosphoglycerate kinase Tpet_0242 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 148270274 Nonpathogen - hypothetical protein Tpet_1144 4 None None None 148269357 Common - biotin/lipoyl attachment domain-containing protein Tpet_0212 213 COG1038 PycA, Pyruvate carboxylase Energy production and conversion 148270878 Nonpathogen - Uncharacterized protein involved in the oxidation of intracellular sulfur-like protein Tpet_1761 2 COG2923 DsrF, Uncharacterized protein involved in the oxidation of intracellular sulfur Inorganic ion transport and metabolism 148269291 Nonpathogen - glycosidase, PH1107-related Tpet_0146 14 COG2152 COG2152, Predicted glycosylase Carbohydrate transport and metabolism 148269236 Common - cell division protein FtsZ Tpet_0091 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 148269319 Common - flavodoxin/nitric oxide synthase Tpet_0174 82 COG0426 FpaA, Uncharacterized flavoproteins Energy production and conversion 148269438 Nonpathogen - hypothetical protein Tpet_0293 3 None None None 148270828 Common - Histidyl-tRNA synthetase-like protein Tpet_1707 23 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 148269230 Common - response regulator receiver protein Tpet_0085 220 COG2204 AtoC, Response regulator containing CheY-like receiver, AAA-type ATPase, and DNA-binding domains Signal transduction mechanisms 148269964 Nonpathogen - Rubrerythrin Tpet_0829 9 COG1633 COG1633, Uncharacterized conserved protein Function unknown 148270451 Common - ribosomal protein L17 Tpet_1321 216 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 148269735 Nonpathogen - hypothetical protein Tpet_0598 2 None None None 148270241 Common - bifunctional 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II protein Tpet_1111 230 COG0807 RibA, GTP cyclohydrolase II Coenzyme metabolism 148270718 Common - 6-phosphogluconolactonase Tpet_1596 125 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 148270351 Common rplS 50S ribosomal protein L19 Tpet_1221 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 148269592 Common - response regulator receiver protein Tpet_0452 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148270344 Common secA preprotein translocase subunit SecA Tpet_1214 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 148269472 Common - Peptidoglycan glycosyltransferase Tpet_0327 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 148269987 Common - binding-protein-dependent transport systems inner membrane component Tpet_0852 215 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148270134 Common - hypothetical protein Tpet_1000 12 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 148270703 Common - alpha-glucan phosphorylase Tpet_1581 150 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 148269360 Common - CBS domain containing protein Tpet_0215 242 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 148269636 Common gldA glycerol dehydrogenase Tpet_0498 117 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 148270477 Common - protein of unknown function DUF205 Tpet_1347 170 COG0344 COG0344, Predicted membrane protein Function unknown 148269973 Common - integral membrane protein MviN Tpet_0838 202 COG0728 MviN, Uncharacterized membrane protein, putative virulence factor General function prediction only 148270322 Nonpathogen - hypothetical protein Tpet_1192 3 None None None 148270925 Nonpathogen - hypothetical protein Tpet_1809 6 COG0823 TolB, Periplasmic component of the Tol biopolymer transport system Intracellular trafficking and secretion 148270699 Common - hydroxylamine reductase Tpet_1577 75 COG1151 COG1151, 6Fe-6S prismane cluster-containing protein Energy production and conversion 148269252 Common - iron-containing alcohol dehydrogenase Tpet_0107 161 COG1979 COG1979, Uncharacterized oxidoreductases, Fe-dependent alcohol dehydrogenase family Energy production and conversion 148270676 Common - binding-protein-dependent transport systems inner membrane component Tpet_1553 151 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148270393 Common - Abortive infection protein Tpet_1263 7 None None None 148270471 Common - ribosomal protein S9 Tpet_1341 249 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 148270516 Common - phosphatidate cytidylyltransferase Tpet_1386 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 148269491 Common - DegT/DnrJ/EryC1/StrS aminotransferase Tpet_0346 192 COG0399 WecE, Predicted pyridoxal phosphate-dependent enzyme apparently involved in regulation of cell wall biogenesis Cell envelope biogenesis, outer membrane 148270769 Common - adenylosuccinate lyase Tpet_1648 240 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 148269903 Nonpathogen - hypothetical protein Tpet_0768 3 COG2052 COG2052, Uncharacterized protein conserved in bacteria Function unknown 148269522 Common - hydro-lyase, Fe-S type, tartrate/fumarate subfamily, beta subunit Tpet_0380 146 COG1838 FumA, Tartrate dehydratase beta subunit/Fumarate hydratase class I, C-terminal domain Energy production and conversion 148269886 Common hppA membrane-bound proton-translocating pyrophosphatase Tpet_0751 98 COG3808 OVP1, Inorganic pyrophosphatase Energy production and conversion 148269873 Common - response regulator receiver modulated metal dependent phosphohydrolase Tpet_0738 225 COG3437 COG3437, Response regulator containing a CheY-like receiver domain and an HD-GYP domain Transcription / Signal transduction mechanisms 148270079 Common - binding-protein-dependent transport systems inner membrane component Tpet_0945 174 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 148269859 Common - hydrogenase, Fe-only Tpet_0723 182 COG4624 COG4624, Iron only hydrogenase large subunit, C-terminal domain General function prediction only 148269710 Common - chorismate synthase Tpet_0573 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 148270558 Common - putative anti-sigma regulatory factor, serine/threonine protein kinase Tpet_1429 188 COG2172 RsbW, Anti-sigma regulatory factor (Ser/Thr protein kinase) Signal transduction mechanisms 148270116 Common - ErfK/YbiS/YcfS/YnhG family protein Tpet_0982 90 COG1376 ErfK, Uncharacterized protein conserved in bacteria Function unknown 148269474 Nonpathogen - hypothetical protein Tpet_0329 1 None None None 148269430 Common - lipopolysaccharide biosynthesis protein Tpet_0285 121 COG3206 GumC, Uncharacterized protein involved in exopolysaccharide biosynthesis Cell envelope biogenesis, outer membrane 148270070 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase Tpet_0936 205 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 148269719 Common - Radical SAM N-terminal domain protein Tpet_0582 77 COG1032 COG1032, Fe-S oxidoreductase Energy production and conversion 148269483 Common - ATP-dependent metalloprotease FtsH Tpet_0338 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 148270097 Nonpathogen - hypothetical protein Tpet_0963 2 None None None 148270403 Common - Tetrahydrodipicolinate succinyltransferase N-terminal domain protein Tpet_1273 189 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 148270640 Common - aminotransferase, class I and II Tpet_1516 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 148269384 Common - Methyltransferase type 11 Tpet_0239 31 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 148269479 Common - Rhomboid family protein Tpet_0334 178 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 148269705 Common - ABC transporter related Tpet_0568 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 148270435 Common - ribosomal protein S14 Tpet_1305 197 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 148270365 Common - DNA repair protein RadC Tpet_1235 178 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 148270418 Common - 30S ribosomal protein S7 Tpet_1288 249 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 148270317 Common tsf elongation factor Ts Tpet_1187 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 148270734 Common - protein of unknown function DUF58 Tpet_1612 16 COG1721 COG1721, Uncharacterized conserved protein (some members contain a von Willebrand factor type A (vWA) domain) General function prediction only 148270084 Nonpathogen - hypothetical protein Tpet_0950 3 None None None 148270411 Common - peptidase, membrane zinc metallopeptidase, putative Tpet_1281 42 COG2738 COG2738, Predicted Zn-dependent protease General function prediction only 148269685 Nonpathogen - transcriptional regulators-like protein Tpet_0548 13 COG1318 COG1318, Predicted transcriptional regulators Transcription 148269325 Nonpathogen - hypothetical protein Tpet_0180 2 None None None 148270882 Common - methyl-accepting chemotaxis sensory transducer Tpet_1766 150 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148269261 Common - binding-protein-dependent transport systems inner membrane component Tpet_0116 163 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148269544 Common - putative GAF sensor protein Tpet_0402 84 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 148269155 Common - phosphate transporter Tpet_0010 152 COG0306 PitA, Phosphate/sulphate permeases Inorganic ion transport and metabolism 148270607 Common - aldo/keto reductase Tpet_1483 189 COG0667 Tas, Predicted oxidoreductases (related to aryl-alcohol dehydrogenases) Energy production and conversion 148270218 Common - CRISPR-associated protein Cas6 Tpet_1088 10 COG1583 COG1583, Uncharacterized protein predicted to be involved in DNA repair (RAMP superfamily) DNA replication, recombination, and repair 148269827 Common - cell cycle protein Tpet_0691 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 148269259 Common - N-acetylglucosamine-6-phosphate deacetylase Tpet_0114 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 148269553 Common - NAD-dependent epimerase/dehydratase Tpet_0413 233 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 148269239 Common - DNA gyrase, B subunit Tpet_0094 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 148269571 Nonpathogen - hypothetical protein Tpet_0431 3 None None None 148269914 Common clpX ATP-dependent protease ATP-binding subunit Tpet_0779 231 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 148270793 Common - rhamnulose-1-phosphate aldolase Tpet_1672 73 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 148269955 Common - inner-membrane translocator Tpet_0820 126 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 148270550 Common - twitching motility protein Tpet_1421 172 COG2805 PilT, Tfp pilus assembly protein, pilus retraction ATPase PilT Cell motility and secretion / Intracellular trafficking and secretion 148269245 Common - ABC-type cobalamin/Fe3+-siderophores transport systems ATPase components-like protein Tpet_0100 144 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 148269198 Common - peptidase M22, glycoprotease Tpet_0053 6 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 148269536 Common - small GTP-binding protein Tpet_0394 237 COG2262 HflX, GTPases General function prediction only 148270847 Common - major facilitator superfamily MFS_1 Tpet_1726 230 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 148270051 Common - Mandelate racemase/muconate lactonizing enzyme, C-terminal domain protein Tpet_0917 134 COG4948 COG4948, L-alanine-DL-glutamate epimerase and related enzymes of enolase superfamily Cell envelope biogenesis, outer membrane / General function prediction only 148269527 Nonpathogen - hypothetical protein Tpet_0385 1 None None None 148270339 Nonpathogen - hypothetical protein Tpet_1209 2 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 148270614 Common - glycoside hydrolase, family 4 Tpet_1490 51 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 148269557 Common - binding-protein-dependent transport systems inner membrane component Tpet_0417 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 148269770 Common - binding-protein-dependent transport systems inner membrane component Tpet_0634 150 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 148269833 Common - NADH-quinone oxidoreductase, E subunit Tpet_0697 157 COG1905 NuoE, NADH:ubiquinone oxidoreductase 24 kD subunit Energy production and conversion 148269659 Common - two component transcriptional regulator, winged helix family Tpet_0521 226 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 148270605 Common - Radical SAM domain protein Tpet_1480 56 COG0641 AslB, Arylsulfatase regulator (Fe-S oxidoreductase) General function prediction only 148270834 Common - phosphoribosylformimino-5-aminoimidazole carboxamide ribotide isomerase Tpet_1713 214 COG0106 HisA, Phosphoribosylformimino-5-aminoimidazole carboxamide ribonucleotide (ProFAR) isomerase Amino acid transport and metabolism 148269652 Common - pyruvate ferredoxin/flavodoxin oxidoreductase Tpet_0514 67 COG1014 PorG, Pyruvate:ferredoxin oxidoreductase and related 2-oxoacid:ferredoxin oxidoreductases, gamma subunit Energy production and conversion 148269216 Common - tRNA pseudouridine synthase B Tpet_0071 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 148269918 Common - anthranilate synthase component I Tpet_0783 223 COG0147 TrpE, Anthranilate/para-aminobenzoate synthases component I Amino acid transport and metabolism / Coenzyme metabolism 148270786 Common - ribosomal L11 methyltransferase Tpet_1665 171 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 148269921 Common - Phosphoribosylanthranilate isomerase Tpet_0786 201 COG0135 TrpF, Phosphoribosylanthranilate isomerase Amino acid transport and metabolism 148270495 Common - methyl-accepting chemotaxis sensory transducer Tpet_1365 167 COG0840 Tar, Methyl-accepting chemotaxis protein Cell motility and secretion / Signal transduction mechanisms 148269286 Common - thiamine biosynthesis protein ThiC Tpet_0141 190 COG0422 ThiC, Thiamine biosynthesis protein ThiC Coenzyme metabolism