Streptococcus suis 05ZYH33, complete genome NC_009442 GI_Number Pathogen_associated Gene_name Product Synonym Number_of_Genera COG_Number COG_Description COG_Category 146319384 Common - hypothetical protein SSU05_1730 177 COG1327 COG1327, Predicted transcriptional regulator, consists of a Zn-ribbon and ATP-cone domains Transcription 146318160 Common - Collagenase and related protease SSU05_0506 139 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 146317784 Common - Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB SSU05_0126 220 COG2804 PulE, Type II secretory pathway, ATPase PulE/Tfp pilus assembly pathway, ATPase PilB Cell motility and secretion / Intracellular trafficking and secretion 146319098 Common - Maltodextrin phosphorylase SSU05_1444 128 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 146319620 Common - Adenylosuccinate synthase SSU05_1966 235 COG0104 PurA, Adenylosuccinate synthase Nucleotide transport and metabolism 146318052 Common - Phosphotransferase system IIC component, glucose/maltose/N-acetylglucosamine-specific SSU05_0397 4 None None None 146317975 Common - NADPH:quinone reductase and related Zn-dependent oxidoreductase SSU05_0319 166 COG0604 Qor, NADPH:quinone reductase and related Zn-dependent oxidoreductases Energy production and conversion / General function prediction only 146318513 Pathogen - hypothetical protein SSU05_0859 1 None None None 146318659 Pathogen - hypothetical protein SSU05_1006 1 None None None 146318336 Common - hypothetical protein SSU05_0682 75 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 146317960 Common - amidase SSU05_0304 216 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 146318307 Common - DNA uptake protein and related DNA-binding proteins SSU05_0653 111 COG1555 ComEA, DNA uptake protein and related DNA-binding proteins DNA replication, recombination, and repair 146317724 Common - RecA/RadA recombinase SSU05_0064 214 COG0468 RecA, RecA/RadA recombinase DNA replication, recombination, and repair 146318190 Common - hypothetical protein SSU05_0536 23 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 146319824 Common trmU tRNA (5-methylaminomethyl-2-thiouridylate)-methyltransferase SSU05_2170 212 COG0482 TrmU, Predicted tRNA(5-methylaminomethyl-2-thiouridylate) methyltransferase, contains the PP-loop ATPase domain Translation, ribosomal structure and biogenesis 146319091 Common - ADP-ribose pyrophosphatase SSU05_1437 27 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146318079 Common - primosome assembly protein PriA SSU05_0424 214 COG1198 PriA, Primosomal protein N' (replication factor Y) - superfamily II helicase DNA replication, recombination, and repair 146318024 Common nadD nicotinic acid mononucleotide adenyltransferase SSU05_0369 176 COG1057 NadD, Nicotinic acid mononucleotide adenylyltransferase Coenzyme metabolism 146318982 Common - Membrane protein involved in the export of O-antigen and teichoic acid SSU05_1328 39 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 146318960 Common - homoserine O-succinyltransferase SSU05_1306 64 COG1897 MetA, Homoserine trans-succinylase Amino acid transport and metabolism 146317970 Common - hypothetical protein SSU05_0314 16 COG4475 COG4475, Uncharacterized protein conserved in bacteria Function unknown 146318734 Common - ABC-type uncharacterized transport system, permease component SSU05_1080 107 COG4603 COG4603, ABC-type uncharacterized transport system, permease component General function prediction only 146318518 Common - putative replication initiator protein SSU05_0864 5 COG0466 Lon, ATP-dependent Lon protease, bacterial type Posttranslational modification, protein turnover, chaperones 146318636 Pathogen - hypothetical protein SSU05_0982 1 None None None 146319322 Common - Hemolysins and related proteins containing CBS domains SSU05_1668 219 COG1253 TlyC, Hemolysins and related proteins containing CBS domains General function prediction only 146318199 Common - Methyl-accepting chemotaxis protein SSU05_0545 8 None None None 146318317 Common - hypothetical protein SSU05_0663 15 COG4467 COG4467, Uncharacterized protein conserved in bacteria Function unknown 146319786 Common - 4-alpha-glucanotransferase SSU05_2132 62 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 146319375 Common - hypothetical protein SSU05_1721 1 None None None 146318411 Common - Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit SSU05_0757 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 146318877 Common - Sugar kinase, ribokinase family SSU05_1223 73 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 146319401 Pathogen - hypothetical protein SSU05_1747 1 None None None 146319832 Pathogen - hypothetical protein SSU05_2178 1 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 146319682 Common - lantibiotic efflux protein SSU05_2028 13 None None None 146319528 Common - Selenocysteine lyase SSU05_1874 239 COG0520 CsdB, Selenocysteine lyase Amino acid transport and metabolism 146319285 Common - uridine kinase SSU05_1631 81 COG0572 Udk, Uridine kinase Nucleotide transport and metabolism 146318648 Common - Predicted membrane protein SSU05_0994 119 COG1272 COG1272, Predicted membrane protein, hemolysin III homolog General function prediction only 146318741 Common - 16S RNA G1207 methylase RsmC SSU05_1087 108 COG2813 RsmC, 16S RNA G1207 methylase RsmC Translation, ribosomal structure and biogenesis 146317800 Common - EMAP domain protein SSU05_0142 200 COG0073 ARC1, EMAP domain General function prediction only 146317965 Common - Cation transport ATPase SSU05_0309 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 146319332 Common - hypothetical protein SSU05_1678 11 COG4470 COG4470, Uncharacterized protein conserved in bacteria Function unknown 146319088 Common - Predicted membrane protein SSU05_1434 9 COG4478 COG4478, Predicted membrane protein Function unknown 146318581 Pathogen - hypothetical protein SSU05_0927 6 None None None 146319256 Common - Transcriptional regulator SSU05_1602 16 COG1846 MarR, Transcriptional regulators Transcription 146318460 Common - ABC-type spermidine/putrescine transport system, permease component I SSU05_0806 212 COG1176 PotB, ABC-type spermidine/putrescine transport system, permease component I Amino acid transport and metabolism 146317754 Common - 30S ribosomal protein S11 SSU05_0094 243 COG0100 RpsK, Ribosomal protein S11 Translation, ribosomal structure and biogenesis 146318063 Pathogen - Predicted lactoylglutathione lyase SSU05_0408 1 COG3607 COG3607, Predicted lactoylglutathione lyase General function prediction only 146317988 Pathogen - hypothetical protein SSU05_0332 1 None None None 146319041 Common - amylase-binding protein B SSU05_1387 20 COG4690 PepD, Dipeptidase Amino acid transport and metabolism 146317949 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_0293 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146318693 Common - Transcriptional antiterminator SSU05_1039 27 COG3711 BglG, Transcriptional antiterminator Transcription 146318920 Common - Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily SSU05_1266 43 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 146317818 Common - Glutamine synthetase SSU05_0160 224 COG0174 GlnA, Glutamine synthetase Amino acid transport and metabolism 146319129 Pathogen - hypothetical protein SSU05_1475 1 None None None 146319431 Common - Predicted hydrolase of the HAD superfamily SSU05_1777 113 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 146317993 Common - fructose-bisphosphate aldolase class-II SSU05_0337 6 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 146318896 Pathogen - hypothetical protein SSU05_1242 1 None None None 146317868 Common - Phosphotransferase system cellobiose-specific component IIC SSU05_0212 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 146319196 Common - hypothetical protein SSU05_1542 67 COG1636 COG1636, Uncharacterized protein conserved in bacteria Function unknown 146319656 Pathogen - hypothetical protein SSU05_2002 3 None None None 146318965 Common - hypothetical protein SSU05_1311 6 None None None 146319048 Common - Permease of the major facilitator superfamily SSU05_1394 40 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146318239 Common - Transposase and inactivated derivative SSU05_0585 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318122 Common - Predicted membrane GTPase involved in stress response SSU05_0468 249 COG1217 TypA, Predicted membrane GTPase involved in stress response Signal transduction mechanisms 146317805 Common groES co-chaperonin GroES SSU05_0147 201 COG0234 GroS, Co-chaperonin GroES (HSP10) Posttranslational modification, protein turnover, chaperones 146318502 Common prfA peptide chain release factor 1 SSU05_0848 216 COG0216 PrfA, Protein chain release factor A Translation, ribosomal structure and biogenesis 146319342 Common - putative ATPase SSU05_1688 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146318929 Common - Glycosyltransferases involved in cell wall biogenesis SSU05_1275 6 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146318816 Common - Transcriptional regulator SSU05_1162 115 COG2186 FadR, Transcriptional regulators Transcription 146319482 Common uvrA excinuclease ABC subunit A SSU05_1828 242 COG0178 UvrA, Excinuclease ATPase subunit DNA replication, recombination, and repair 146319134 Common - Predicted hydrolase of the metallo-beta-lactamase superfamily SSU05_1480 159 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 146318465 Common - Subtilisin-like serine protease SSU05_0811 25 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 146319736 Common - Predicted metalloendopeptidase SSU05_2082 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 146317760 Common - hypothetical protein SSU05_0102 8 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 146319625 Common - hypothetical protein SSU05_1971 57 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146318870 Common - Preprotein translocase subunit YajC SSU05_1216 5 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 146319517 Common - Transposase and inactivated derivative SSU05_1863 95 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318378 Common - Glycerol uptake facilitator protein SSU05_0724 124 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 146318555 Common - tRNA (uracil-5-)-methyltransferase Gid SSU05_0901 193 COG1206 Gid, NAD(FAD)-utilizing enzyme possibly involved in translation Translation, ribosomal structure and biogenesis 146319691 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_2037 211 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146319081 Common - Predicted metal-sulfur cluster biosynthetic enzyme SSU05_1427 146 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 146319396 Common - Cell division protein FtsI/penicillin-binding protein 2 SSU05_1742 207 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 146317696 Common - hypothetical protein SSU05_0036 2 None None None 146319067 Pathogen - hypothetical protein SSU05_1413 1 None None None 146319621 Common - bifunctional glutamate--cysteine ligase/glutathione synthetase SSU05_1967 99 COG2918 GshA, Gamma-glutamylcysteine synthetase Coenzyme metabolism 146318245 Pathogen - hypothetical protein SSU05_0591 1 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146318175 Common - hypothetical protein SSU05_0521 84 COG2606 EbsC, Uncharacterized conserved protein Function unknown 146318906 Common aroB 3-dehydroquinate synthase SSU05_1252 205 COG0337 AroB, 3-dehydroquinate synthetase Amino acid transport and metabolism 146318851 Common - lantibiotic efflux protein SSU05_1197 28 None None None 146319511 Common - Methyl-accepting chemotaxis protein SSU05_1857 1 None None None 146317956 Common - Molecular chaperone SSU05_0300 235 COG0443 DnaK, Molecular chaperone Posttranslational modification, protein turnover, chaperones 146317904 Common - ABC-type antimicrobial peptide transport system, ATPase component SSU05_0248 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 146318828 Common - F0F1 ATP synthase subunit alpha SSU05_1174 247 COG0056 AtpA, F0F1-type ATP synthase, alpha subunit Energy production and conversion 146317944 Common - Na+-driven multidrug efflux pump SSU05_0288 181 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 146319548 Common - Predicted metal-sulfur cluster biosynthetic enzyme SSU05_1894 131 COG2151 PaaD, Predicted metal-sulfur cluster biosynthetic enzyme General function prediction only 146318267 Common - aspartate aminotransferase SSU05_0613 239 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 146319360 Common - glutamate racemase SSU05_1706 190 COG0796 MurI, Glutamate racemase Cell envelope biogenesis, outer membrane 146319345 Common - putative phosphotyrosine protein phosphatase SSU05_1691 126 COG0394 Wzb, Protein-tyrosine-phosphatase Signal transduction mechanisms 146317722 Common - Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA SSU05_0062 150 COG1058 CinA, Predicted nucleotide-utilizing enzyme related to molybdopterin-biosynthesis enzyme MoeA General function prediction only 146318767 Common - bifunctional riboflavin kinase/FMN adenylyltransferase SSU05_1113 211 COG0196 RibF, FAD synthase Coenzyme metabolism 146318188 Common - Predicted permease SSU05_0534 11 COG0730 COG0730, Predicted permeases General function prediction only 146319448 Pathogen - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_1794 1 None None None 146319576 Common - endo-beta-N-acetylglucosaminidase, putative SSU05_1922 13 COG4724 COG4724, Endo-beta-N-acetylglucosaminidase D Carbohydrate transport and metabolism 146317690 Common - Folate-dependent phosphoribosylglycinamide formyltransferase PurN SSU05_0030 183 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 146317811 Pathogen - hypothetical protein SSU05_0154 1 None None None 146317779 Common rpoB DNA-directed RNA polymerase subunit beta SSU05_0121 249 COG0085 RpoB, DNA-directed RNA polymerase, beta subunit/140 kD subunit Transcription 146319599 Common - Putative translation factor (SUA5) SSU05_1945 4 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 146319477 Common - Translation elongation factor P (EF-P) SSU05_1823 216 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 146319752 Common - sortase-like protein SSU05_2098 15 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 146318326 Common - putative 3'-exo-deoxyribonuclease SSU05_0672 5 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 146319606 Common - hypothetical protein SSU05_1952 28 COG3560 FMR2, Predicted oxidoreductase related to nitroreductase General function prediction only 146318229 Pathogen - hypothetical protein SSU05_0575 2 None None None 146319313 Common - hypothetical protein SSU05_1659 15 COG1755 COG1755, Uncharacterized protein conserved in bacteria Function unknown 146318952 Common - dTDP-glucose 4,6-dehydratase SSU05_1298 231 COG1088 RfbB, dTDP-D-glucose 4,6-dehydratase Cell envelope biogenesis, outer membrane 146319159 Common - Glycerate kinase SSU05_1505 81 COG1929 COG1929, Glycerate kinase Carbohydrate transport and metabolism 146319425 Common - ABC-type metal ion transport system, periplasmic component/surface antigen SSU05_1771 99 COG1464 NlpA, ABC-type metal ion transport system, periplasmic component/surface antigen Inorganic ion transport and metabolism 146319600 Common leuD isopropylmalate isomerase small subunit SSU05_1946 214 COG0066 LeuD, 3-isopropylmalate dehydratase small subunit Amino acid transport and metabolism 146319497 Common - Clostridium cellulosome enzyme, dockerin type I SSU05_1843 38 None None None 146319500 Common infB translation initiation factor IF-2 SSU05_1846 249 COG0532 InfB, Translation initiation factor 2 (IF-2; GTPase) Translation, ribosomal structure and biogenesis 146319720 Common - Transcriptional regulator SSU05_2066 126 COG1609 PurR, Transcriptional regulators Transcription 146318404 Pathogen - hypothetical protein SSU05_0750 1 None None None 146318951 Pathogen - hypothetical protein SSU05_1297 1 None None None 146317677 Common - ATP-dependent Zn protease SSU05_0015 249 COG0465 HflB, ATP-dependent Zn proteases Posttranslational modification, protein turnover, chaperones 146318935 Common - Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases SSU05_1281 36 COG1442 RfaJ, Lipopolysaccharide biosynthesis proteins, LPS:glycosyltransferases Cell envelope biogenesis, outer membrane 146318713 Common ppnK inorganic polyphosphate/ATP-NAD kinase SSU05_1059 237 COG0061 COG0061, Predicted sugar kinase Carbohydrate transport and metabolism 146318755 Common - ABC-type phosphate transport system, ATPase component SSU05_1101 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 146318418 Common - DNA topoisomerase IV subunit A SSU05_0764 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 146317895 Common - Acyl-coenzyme A synthetases/AMP-(fatty) acid ligase SSU05_0239 74 COG0365 Acs, Acyl-coenzyme A synthetases/AMP-(fatty) acid ligases Lipid metabolism 146319568 Common - ABC-type sugar transport system, periplasmic component SSU05_1914 13 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 146319106 Common - EcoE type I restriction modification enzyme M subunit SSU05_1452 158 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 146319669 Common rnpA ribonuclease P SSU05_2015 82 COG0594 RnpA, RNase P protein component Translation, ribosomal structure and biogenesis 146319408 Common - Major membrane immunogen, membrane-anchored lipoprotein SSU05_1754 10 COG4939 COG4939, Major membrane immunogen, membrane-anchored lipoprotein Function unknown 146318808 Common - hypothetical protein SSU05_1154 179 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 146319279 Common - biotin--protein ligase SSU05_1625 197 COG0340 BirA, Biotin-(acetyl-CoA carboxylase) ligase Coenzyme metabolism 146319601 Common - 3-isopropylmalate dehydratase large subunit SSU05_1947 223 COG0065 LeuC, 3-isopropylmalate dehydratase large subunit Amino acid transport and metabolism 146317917 Common - Predicted membrane protein SSU05_0261 37 COG1511 COG1511, Predicted membrane protein Function unknown 146318626 Pathogen - hypothetical protein SSU05_0972 1 None None None 146318593 Pathogen - Methyl-accepting chemotaxis protein SSU05_0939 1 None None None 146319702 Pathogen - hypothetical protein SSU05_2048 1 None None None 146319709 Common - putative L-ascorbate 6-phosphate lactonase SSU05_2055 32 COG2220 COG2220, Predicted Zn-dependent hydrolases of the beta-lactamase fold General function prediction only 146318059 Common - Predicted membrane protein SSU05_0404 13 COG4720 COG4720, Predicted membrane protein Function unknown 146318014 Common - Transcriptional regulator SSU05_0359 116 COG1609 PurR, Transcriptional regulators Transcription 146319186 Common - lipoprotein involved thiamine biosynthesis SSU05_1532 132 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 146318429 Pathogen - hypothetical protein SSU05_0775 1 None None None 146317789 Common - Competence protein ComGF SSU05_0131 2 COG4940 ComGF, Competence protein ComGF Intracellular trafficking and secretion 146318798 Common - GTP cyclohydrolase I SSU05_1144 177 COG0302 FolE, GTP cyclohydrolase I Coenzyme metabolism 146319793 Common - Protein involved in ribonucleotide reduction SSU05_2139 27 COG1780 NrdI, Protein involved in ribonucleotide reduction Nucleotide transport and metabolism 146318891 Common - hypothetical protein SSU05_1237 7 COG4894 COG4894, Uncharacterized conserved protein Function unknown 146318192 Common - Adenosine deaminase SSU05_0538 107 COG1816 Add, Adenosine deaminase Nucleotide transport and metabolism 146318446 Common carB carbamoyl phosphate synthase large subunit SSU05_0792 235 COG0458 CarB, Carbamoylphosphate synthase large subunit (split gene in MJ) Amino acid transport and metabolism / Nucleotide transport and metabolism 146318927 Common - Ferredoxin SSU05_1272 4 COG1141 Fer, Ferredoxin Energy production and conversion 146318914 Common - hypothetical protein SSU05_1260 13 COG3679 COG3679, Uncharacterized conserved protein Function unknown 146317714 Common - Transposase and inactivated derivative SSU05_0054 94 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318154 Pathogen - hypothetical protein SSU05_0500 1 None None None 146319744 Common - RevS SSU05_2090 8 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 146317738 Common rplP 50S ribosomal protein L16 SSU05_0078 216 COG0197 RplP, Ribosomal protein L16/L10E Translation, ribosomal structure and biogenesis 146317879 Common - ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member SSU05_0223 72 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 146317793 Common - acetate kinase SSU05_0135 162 COG0282 ackA, Acetate kinase Energy production and conversion 146318203 Common - D-fructose-6-phosphate amidotransferase SSU05_0549 238 COG0449 GlmS, Glucosamine 6-phosphate synthetase, contains amidotransferase and phosphosugar isomerase domains Cell envelope biogenesis, outer membrane 146318272 Common - Na+-driven multidrug efflux pump SSU05_0618 185 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 146318665 Common - dihydroorotate dehydrogenase electron transfer subunit SSU05_1011 79 COG0543 UbiB, 2-polyprenylphenol hydroxylase and related flavodoxin oxidoreductases Coenzyme metabolism / Energy production and conversion 146319775 Common - hypothetical protein SSU05_2121 4 None None None 146319184 Common - Integrase SSU05_1530 9 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146318557 Common - site-specific recombinase, phage integrase family SSU05_0903 78 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146318437 Pathogen - C-P lyase regulatory protein SSU05_0783 1 None None None 146319616 Common - Predicted membrane-associated Zn-dependent proteases 1 SSU05_1962 198 COG0750 COG0750, Predicted membrane-associated Zn-dependent proteases 1 Cell envelope biogenesis, outer membrane 146318478 Common - Phosphotransferase system, fructose-specific IIC component SSU05_0824 142 COG1445 FrwB, Phosphotransferase system fructose-specific component IIB Carbohydrate transport and metabolism 146317709 Pathogen - hypothetical protein SSU05_0049 1 None None None 146319223 Common - Acyl carrier protein phosphodiesterase SSU05_1569 78 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 146319309 Common - exodeoxyribonuclease VII small subunit SSU05_1655 69 COG1722 XseB, Exonuclease VII small subunit DNA replication, recombination, and repair 146318288 Common - 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase SSU05_0634 90 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 146318548 Common - ABC-type multidrug transport system, ATPase component SSU05_0894 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146319717 Common - ascorbate-specific PTS system enzyme IIC SSU05_2063 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 146318699 Common - Transcriptional regulator of sugar metabolism SSU05_1045 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 146319810 Common rpsD 30S ribosomal protein S4 SSU05_2156 249 COG0522 RpsD, Ribosomal protein S4 and related proteins Translation, ribosomal structure and biogenesis 146318889 Pathogen - hypothetical protein SSU05_1235 1 None None None 146319265 Common - hypothetical protein SSU05_1611 12 COG3091 SprT, Uncharacterized protein conserved in bacteria Function unknown 146319239 Common - hypothetical protein SSU05_1585 35 COG4405 COG4405, Uncharacterized protein conserved in bacteria Function unknown 146319218 Pathogen - hypothetical protein SSU05_1564 1 None None None 146318352 Pathogen - hypothetical protein SSU05_0698 1 None None None 146318454 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_0800 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146317883 Pathogen - Predicted dehydrogenase and related proteins SSU05_0227 1 None None None 146318880 Common - transposase SSU05_1226 62 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318692 Common - Phosphotransferase system cellobiose-specific component IIA SSU05_1038 32 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 146319801 Common - beta-glucosidase SSU05_2147 89 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 146317869 Common - hypothetical protein SSU05_0213 2 None None None 146319535 Common - ABC-type amino acid transport/signal transduction system, periplasmic component/domain SSU05_1881 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146319206 Common upp uracil phosphoribosyltransferase SSU05_1553 166 COG0035 Upp, Uracil phosphoribosyltransferase Nucleotide transport and metabolism 146319414 Common - K+ transport system, NAD-binding component SSU05_1760 127 COG0569 TrkA, K+ transport systems, NAD-binding component Inorganic ion transport and metabolism 146318241 Common - Transposase and inactivated derivative SSU05_0587 50 COG3436 COG3436, Transposase and inactivated derivatives DNA replication, recombination, and repair 146319566 Pathogen - Predicted integral membrane protein SSU05_1912 1 COG5578 COG5578, Predicted integral membrane protein Function unknown 146318453 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_0799 159 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146319023 Common - Glycosyltransferase SSU05_1369 222 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146318359 Common - Pyruvate-formate lyase-activating enzyme SSU05_0705 65 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 146317774 Common - Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases SSU05_0116 44 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 146318721 Common - hypothetical protein SSU05_1067 7 None None None 146318800 Common - hypothetical protein SSU05_1146 10 COG1285 SapB, Uncharacterized membrane protein Function unknown 146319381 Common - Nitroreductase SSU05_1727 62 COG0778 NfnB, Nitroreductase Energy production and conversion 146318269 Pathogen - hypothetical protein SSU05_0615 1 None None None 146319290 Common - Lactoylglutathione lyase and related lyases SSU05_1636 128 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 146318395 Common - cobalt ABC transporter ATP-binding protein SSU05_0741 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 146318606 Common - Recombinase SSU05_0952 9 None None None 146318149 Common - ABC-type amino acid transport system, permease component SSU05_0495 156 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146318438 Common - CpsY SSU05_0784 180 COG0583 LysR, Transcriptional regulator Transcription 146319442 Pathogen - hypothetical protein SSU05_1788 1 None None None 146319053 Common - hypothetical protein SSU05_1399 154 COG0319 COG0319, Predicted metal-dependent hydrolase General function prediction only 146318449 Common - hypothetical protein SSU05_0795 2 None None None 146318831 Common - F0F1-type ATP synthase, subunit a SSU05_1177 123 COG0356 AtpB, F0F1-type ATP synthase, subunit a Energy production and conversion 146318213 Common - Pyrroline-5-carboxylate reductase SSU05_0559 216 COG0345 ProC, Pyrroline-5-carboxylate reductase Amino acid transport and metabolism 146318826 Common - F0F1 ATP synthase subunit beta SSU05_1172 247 COG0055 AtpD, F0F1-type ATP synthase, beta subunit Energy production and conversion 146319635 Common - hypothetical protein SSU05_1981 3 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 146319270 Common - Predicted membrane protein SSU05_1616 72 COG1295 Rbn, Predicted membrane protein Function unknown 146317681 Common - Phosphoribosylpyrophosphate synthetase SSU05_0021 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 146317926 Common - hypothetical protein SSU05_0270 77 COG0433 COG0433, Predicted ATPase General function prediction only 146318753 Common - Transposase and inactivated derivative SSU05_1099 77 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 146319588 Common rpsO 30S ribosomal protein S15 SSU05_1934 215 COG0184 RpsO, Ribosomal protein S15P/S13E Translation, ribosomal structure and biogenesis 146319505 Common trmB tRNA (guanine-N(7))-methyltransferase SSU05_1851 178 COG0220 COG0220, Predicted S-adenosylmethionine-dependent methyltransferase General function prediction only 146317841 Common - Predicted flavoprotein SSU05_0183 142 COG2081 COG2081, Predicted flavoproteins General function prediction only 146319760 Common - hypothetical protein SSU05_2106 166 COG1385 COG1385, Uncharacterized protein conserved in bacteria Function unknown 146319039 Common - Cation transport ATPase SSU05_1385 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 146318495 Common - GTP-binding protein LepA SSU05_0841 249 COG0481 LepA, Membrane GTPase LepA Cell envelope biogenesis, outer membrane 146317830 Common - Alpha-galactosidase SSU05_0172 45 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 146319204 Common - ATP-dependent CLP protease proteolytic subunit SSU05_1550 8 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 146318206 Common - amino acid ABC transporter, amino acid-binding protein SSU05_0552 176 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146317695 Common - phosphoribosylaminoimidazole carboxylase ATPase subunit SSU05_0035 193 COG0026 PurK, Phosphoribosylaminoimidazole carboxylase (NCAIR synthetase) Nucleotide transport and metabolism 146318043 Common - N-formylmethionyl-tRNA deformylase SSU05_0388 57 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 146318221 Common - Cps2D SSU05_0567 39 COG4464 CapC, Capsular polysaccharide biosynthesis protein Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 146319338 Common - hypothetical protein SSU05_1684 9 COG4483 COG4483, Uncharacterized protein conserved in bacteria Function unknown 146319842 Pathogen - hypothetical protein SSU05_2189 1 None None None 146318426 Common - putative ribosomal protein S1-like DNA-binding protein SSU05_0772 6 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 146318725 Common - DNA repair protein SSU05_1071 177 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 146318778 Common - hypothetical protein SSU05_1124 26 COG4487 COG4487, Uncharacterized protein conserved in bacteria Function unknown 146319654 Common - Permease of the major facilitator superfamily SSU05_2000 4 None None None 146317991 Common - CTP synthetase SSU05_0335 246 COG0504 PyrG, CTP synthase (UTP-ammonia lyase) Nucleotide transport and metabolism 146318007 Common rplS 50S ribosomal protein L19 SSU05_0352 216 COG0335 RplS, Ribosomal protein L19 Translation, ribosomal structure and biogenesis 146318660 Pathogen - hypothetical protein SSU05_1005 1 None None None 146317837 Pathogen - Putative RTX family exoprotein A gene SSU05_0179 4 None None None 146319456 Common - 3-oxoacyl-(acyl carrier protein) synthase II SSU05_1802 210 COG0304 FabB, 3-oxoacyl-(acyl-carrier-protein) synthase Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146319072 Common - Cation transport ATPase SSU05_1418 231 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 146318297 Common - Predicted glutathione S-transferase SSU05_0643 79 COG0435 ECM4, Predicted glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146319845 Common - hypothetical protein SSU05_2191 166 COG1576 COG1576, Uncharacterized conserved protein Function unknown 146318717 Pathogen - hypothetical protein SSU05_1063 1 COG4116 COG4116, Uncharacterized protein conserved in bacteria Function unknown 146319004 Common - UDP-N-acetylmuramyl pentapeptide synthase SSU05_1350 210 COG0770 MurF, UDP-N-acetylmuramyl pentapeptide synthase Cell envelope biogenesis, outer membrane 146319573 Common - hypothetical protein SSU05_1919 40 COG0383 AMS1, Alpha-mannosidase Carbohydrate transport and metabolism 146317688 Common - amidophosphoribosyltransferase SSU05_0028 240 COG0034 PurF, Glutamine phosphoribosylpyrophosphate amidotransferase Nucleotide transport and metabolism 146317826 Common - ABC-type sugar transport system, periplasmic component SSU05_0168 93 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 146318035 Common - putative transcriptional regulator SSU05_0380 62 COG0789 SoxR, Predicted transcriptional regulators Transcription 146318343 Common - phosphopantothenate--cysteine ligase SSU05_0689 199 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 146318682 Common - ABC-type amino acid transport/signal transduction system, periplasmic component/domain SSU05_1028 174 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146318022 Common - Predicted GTPase SSU05_0367 20 COG1161 COG1161, Predicted GTPases General function prediction only 146318840 Common - Acetyltransferase, including N-acetylases of ribosomal proteins SSU05_1186 126 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 146318971 Common - hypothetical protein SSU05_1317 1 None None None 146318417 Common - hypothetical protein SSU05_0763 4 None None None 146317740 Common rpsQ 30S ribosomal protein S17 SSU05_0080 225 COG0186 RpsQ, Ribosomal protein S17 Translation, ribosomal structure and biogenesis 146318613 Common - putative transposase SSU05_0959 27 None None None 146318490 Common - hypothetical protein SSU05_0836 2 None None None 146319178 Pathogen - hypothetical protein SSU05_1524 1 None None None 146319553 Common - hypothetical protein SSU05_1899 50 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 146318471 Common - hypothetical protein SSU05_0817 41 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 146318367 Common - Phosphotransferase system cellobiose-specific component IIC SSU05_0713 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 146318781 Common - Predicted hydrolase of the HAD superfamily SSU05_1127 148 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 146318099 Common - Uncharacterized domain/protein associated with RNAses G and E SSU05_0445 15 COG3557 COG3557, Uncharacterized domain/protein associated with RNAses G and E Translation, ribosomal structure and biogenesis 146318403 Common uvrC excinuclease ABC subunit C SSU05_0749 223 COG0322 UvrC, Nuclease subunit of the excinuclease complex DNA replication, recombination, and repair 146319769 Common - Predicted acetyltransferase SSU05_2115 27 COG3981 COG3981, Predicted acetyltransferase General function prediction only 146317923 Common - Putative effector of murein hydrolase SSU05_0267 24 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 146318134 Common - Actin-like ATPase involved in cell division SSU05_0480 175 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 146319194 Common holA DNA polymerase III subunit delta SSU05_1540 50 COG1466 HolA, DNA polymerase III, delta subunit DNA replication, recombination, and repair 146317807 Common - GroEL SSU05_0149 230 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 146317797 Common - hypothetical protein SSU05_0139 1 None None None 146318748 Common - Signal transduction histidine kinase SSU05_1094 219 COG2205 KdpD, Osmosensitive K+ channel histidine kinase Signal transduction mechanisms 146319489 Common - hypothetical protein SSU05_1835 33 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 146319362 Common - putative diaminopimelate decarboxylase SSU05_1708 219 COG0019 LysA, Diaminopimelate decarboxylase Amino acid transport and metabolism 146317967 Common truA tRNA pseudouridine synthase A SSU05_0311 236 COG0101 TruA, Pseudouridylate synthase Translation, ribosomal structure and biogenesis 146317786 Common - Competence protein ComGC SSU05_0128 10 COG4537 ComGC, Competence protein ComGC Intracellular trafficking and secretion 146319406 Common - 1,4-dihydroxy-2-naphthoate octaprenyltransferase SSU05_1752 29 COG1575 MenA, 1,4-dihydroxy-2-naphthoate octaprenyltransferase Coenzyme metabolism 146319487 Common - single-strand DNA-binding protein SSU05_1833 214 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 146319027 Common - Xaa-Pro aminopeptidase SSU05_1373 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 146318634 Pathogen - hypothetical protein SSU05_0980 1 None None None 146318270 Pathogen - hypothetical protein SSU05_0616 1 None None None 146319160 Common - Predicted phosphatase SSU05_1506 180 COG0546 Gph, Predicted phosphatases General function prediction only 146317958 Common - DnaJ-class molecular chaperone with C-terminal Zn finger domain SSU05_0302 233 COG0484 DnaJ, DnaJ-class molecular chaperone with C-terminal Zn finger domain Posttranslational modification, protein turnover, chaperones 146319289 Common - Predicted xylanase/chitin deacetylase SSU05_1635 108 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 146318109 Common - hypothetical protein SSU05_0455 2 None None None 146318739 Common - Deoxyribose-phosphate aldolase SSU05_1085 138 COG0274 DeoC, Deoxyribose-phosphate aldolase Nucleotide transport and metabolism 146319627 Common - hypothetical protein SSU05_1973 22 COG3172 NadR, Predicted ATPase/kinase involved in NAD metabolism Coenzyme metabolism 146317707 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_0047 9 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146319277 Common - hypothetical protein SSU05_1623 6 COG3620 COG3620, Predicted transcriptional regulator with C-terminal CBS domains Transcription 146319725 Common - Phosphotransferase system cellobiose-specific component IIC SSU05_2071 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 146318120 Common - hypothetical protein SSU05_0466 12 COG2315 MmcQ, Uncharacterized protein conserved in bacteria Function unknown 146318946 Common - Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily SSU05_1292 32 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 146319012 Common - Signal transduction histidine kinase SSU05_1358 222 COG5002 VicK, Signal transduction histidine kinase Signal transduction mechanisms 146317756 Common - Ribosomal protein L17 SSU05_0096 121 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 146319083 Common dnaG DNA primase SSU05_1429 215 COG0358 DnaG, DNA primase (bacterial type) DNA replication, recombination, and repair 146319531 Common - UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N-acetylglucosamine-1-phosphate transferase SSU05_1877 228 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 146318695 Common - Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) SSU05_1041 99 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 146318849 Pathogen - hypothetical protein SSU05_1195 1 None None None 146319618 Common - Undecaprenyl pyrophosphate synthase SSU05_1964 242 COG0020 UppS, Undecaprenyl pyrophosphate synthase Lipid metabolism 146319037 Common tpx thiol peroxidase SSU05_1383 112 COG2077 Tpx, Peroxiredoxin Posttranslational modification, protein turnover, chaperones 146319444 Common - Integrase SSU05_1790 18 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146319428 Common - 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase SSU05_1774 141 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 146318504 Common - Putative translation factor (SUA5) SSU05_0850 240 COG0009 SUA5, Putative translation factor (SUA5) Translation, ribosomal structure and biogenesis 146318334 Pathogen - hypothetical protein SSU05_0680 1 None None None 146318181 Common - phosphoenolpyruvate carboxylase SSU05_0527 116 COG2352 Ppc, Phosphoenolpyruvate carboxylase Energy production and conversion 146318732 Common - Dihydrofolate reductase SSU05_1078 10 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 146319480 Common - Xaa-Pro aminopeptidase SSU05_1826 5 None None None 146318657 Common - uracil-DNA glycosylase SSU05_1003 129 COG0692 Ung, Uracil DNA glycosylase DNA replication, recombination, and repair 146318757 Common - putative phosphate ABC transporter (permease protein) SSU05_1103 230 COG0581 PstA, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 146317762 Common - hypothetical protein SSU05_0104 16 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 146317940 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_0284 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146318385 Common - Superfamily I DNA and RNA helicase SSU05_0731 232 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 146319785 Common - 4-alpha-glucanotransferase SSU05_2131 105 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 146318110 Common - Superfamily II helicase SSU05_0456 1 None None None 146318750 Pathogen - hypothetical protein SSU05_1096 1 None None None 146319671 Common - argininosuccinate synthase SSU05_2017 216 COG0137 ArgG, Argininosuccinate synthase Amino acid transport and metabolism 146317726 Common - hypothetical protein SSU05_0066 24 COG4472 COG4472, Uncharacterized protein conserved in bacteria Function unknown 146318598 Common - possible two-component sensor histidine kinase SSU05_0944 60 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 146319509 Common - ABC-type multidrug transport system, ATPase component SSU05_1855 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146319130 Common - ATPase component of ABC transporters with duplicated ATPase domains SSU05_1476 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 146319296 Common - Hydroxymethylglutaryl-CoA reductase SSU05_1642 48 COG1257 HMG1, Hydroxymethylglutaryl-CoA reductase Lipid metabolism 146319163 Common - septation ring formation regulator EzrA SSU05_1509 22 COG4477 EzrA, Negative regulator of septation ring formation Cell division and chromosome partitioning 146318119 Common - transcriptional regulator SSU05_0465 45 COG2856 COG2856, Predicted Zn peptidase Amino acid transport and metabolism 146317858 Common - Predicted transcriptional regulator SSU05_0202 15 COG1959 COG1959, Predicted transcriptional regulator Transcription 146318083 Common - Serine/threonine protein kinase SSU05_0428 164 COG0515 SPS1, Serine/threonine protein kinase General function prediction only / Signal transduction mechanisms / Transcription / DNA replication, recombination, and repair 146318975 Common - Phosphate starvation-inducible protein PhoH, predicted ATPase SSU05_1321 199 COG1702 PhoH, Phosphate starvation-inducible protein PhoH, predicted ATPase Signal transduction mechanisms 146317667 Common - Predicted transcriptional regulator SSU05_0005 43 COG1813 COG1813, Predicted transcription factor, homolog of eukaryotic MBF1 Transcription 146318322 Common - Methylated DNA-protein cysteine methyltransferase SSU05_0668 217 COG0350 Ada, Methylated DNA-protein cysteine methyltransferase DNA replication, recombination, and repair 146319658 Common - Antitoxin of toxin-antitoxin stability system SSU05_2004 18 COG2161 StbD, Antitoxin of toxin-antitoxin stability system Cell division and chromosome partitioning 146318065 Common - ABC-type cobalt transport system, permease component CbiQ and related transporters SSU05_0410 68 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 146318026 Pathogen - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_0371 1 None None None 146318406 Common - hypothetical protein SSU05_0752 1 None None None 146317938 Pathogen - hypothetical protein SSU05_0282 1 None None None 146317873 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component SSU05_0217 249 COG1116 TauB, ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component Inorganic ion transport and metabolism 146319373 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_1719 11 COG3153 COG3153, Predicted acetyltransferase General function prediction only 146319169 Pathogen - hypothetical protein SSU05_1515 1 None None None 146319834 Common - Predicted Zn-dependent peptidase SSU05_2180 81 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 146318762 Pathogen - hypothetical protein SSU05_1108 1 None None None 146319370 Common greA transcription elongation factor GreA SSU05_1716 200 COG0782 GreA, Transcription elongation factor Transcription 146318620 Common - Predicted transcriptional regulator SSU05_0966 14 COG5340 COG5340, Predicted transcriptional regulator Transcription 146318879 Common - gluconate 5-dehydrogenase SSU05_1225 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146319227 Common - Predicted transcriptional regulator SSU05_1573 82 COG0640 ArsR, Predicted transcriptional regulators Transcription 146318980 Common frr ribosome recycling factor SSU05_1326 216 COG0233 Frr, Ribosome recycling factor Translation, ribosomal structure and biogenesis 146317969 Common - Predicted membrane protein SSU05_0313 14 COG4720 COG4720, Predicted membrane protein Function unknown 146318583 Pathogen - hypothetical protein SSU05_0929 5 None None None 146319502 Common - Predicted nucleic-acid-binding protein implicated in transcription termination SSU05_1848 33 COG2740 COG2740, Predicted nucleic-acid-binding protein implicated in transcription termination Transcription 146318366 Common - Phosphotransferase system cellobiose-specific component IIC SSU05_0712 9 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 146318882 Pathogen - hypothetical protein SSU05_1228 1 None None None 146317998 Common - RecG-like helicase SSU05_0343 210 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 146319762 Common - hypothetical protein SSU05_2108 176 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 146318640 Common - Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake SSU05_0986 33 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 146318324 Common - Predicted Co/Zn/Cd cation transporter SSU05_0670 9 COG3965 COG3965, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 146318994 Common - ABC-type polysaccharide transport system, permease component SSU05_1340 131 COG4209 LplB, ABC-type polysaccharide transport system, permease component Carbohydrate transport and metabolism 146318473 Common rimM 16S rRNA-processing protein SSU05_0819 153 COG0806 RimM, RimM protein, required for 16S rRNA processing Translation, ribosomal structure and biogenesis 146318360 Common - Transcriptional regulator of sugar metabolism SSU05_0706 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 146319438 Common - Type I restriction-modification system methyltransferase subunit SSU05_1784 155 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 146317679 Common - putative cell shape-determining protein MreC SSU05_0019 23 COG1792 MreC, Cell shape-determining protein Cell envelope biogenesis, outer membrane 146318016 Common - galactose-1-phosphate uridylyltransferase SSU05_0361 14 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 146319108 Common trmE tRNA modification GTPase TrmE SSU05_1454 231 COG0486 ThdF, Predicted GTPase General function prediction only 146319822 Common - transcriptional regulatory protein SSU05_2168 148 COG1733 COG1733, Predicted transcriptional regulators Transcription 146318933 Common - Lipopolysaccharide biosynthesis protein SSU05_1279 38 COG3754 RgpF, Lipopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 146319734 Common - Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases SSU05_2080 21 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 146318481 Common - hypothetical protein SSU05_0827 52 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 146319495 Common - Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit SSU05_1841 154 COG1071 AcoA, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, alpha subunit Energy production and conversion 146318342 Common - phosphopantothenoylcysteine decarboxylase SSU05_0688 234 COG0452 Dfp, Phosphopantothenoylcysteine synthetase/decarboxylase Coenzyme metabolism 146318305 Common murE UDP-N-acetylmuramoylalanyl-D-glutamate--2,6-diaminopimelate ligase SSU05_0651 209 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 146318628 Pathogen - hypothetical protein SSU05_0974 1 None None None 146318844 Common - Chromosome segregation ATPase SSU05_1190 199 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 146318536 Common - Phosphomannomutase SSU05_0882 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 146318488 Common thyA thymidylate synthase SSU05_0834 136 COG0207 ThyA, Thymidylate synthase Nucleotide transport and metabolism 146318901 Common - Predicted membrane protein SSU05_1247 19 COG4330 COG4330, Predicted membrane protein Function unknown 146318591 Common - Predicted transcriptional regulator SSU05_0937 12 COG1396 HipB, Predicted transcriptional regulators Transcription 146318371 Common gldA glycerol dehydrogenase SSU05_0717 148 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 146317911 Common - Predicted hydrolase of the HAD superfamily SSU05_0255 120 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 146319398 Common mraW S-adenosyl-methyltransferase MraW SSU05_1744 215 COG0275 COG0275, Predicted S-adenosylmethionine-dependent methyltransferase involved in cell envelope biogenesis Cell envelope biogenesis, outer membrane 146319136 Common - hypothetical protein SSU05_1482 25 COG3760 COG3760, Uncharacterized conserved protein Function unknown 146317698 Pathogen - hypothetical protein SSU05_0038 2 None None None 146318771 Common - hypothetical protein SSU05_1117 1 COG2461 COG2461, Uncharacterized conserved protein Function unknown 146319061 Pathogen - hypothetical protein SSU05_1407 1 None None None 146318162 Common - hypothetical protein SSU05_0508 11 COG4443 COG4443, Uncharacterized protein conserved in bacteria Function unknown 146319519 Common - ABC-type dipeptide/oligopeptide/nickel transport system, permease component SSU05_1865 219 COG0601 DppB, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 146317893 Common - Thiol-disulfide isomerase and thioredoxin SSU05_0237 233 COG3118 COG3118, Thioredoxin domain-containing protein Posttranslational modification, protein turnover, chaperones 146319807 Common - Succinate dehydrogenase/fumarate reductase, flavoprotein subunit SSU05_2153 211 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 146319623 Common hslO Hsp33-like chaperonin SSU05_1969 130 COG1281 COG1281, Disulfide bond chaperones of the HSP33 family Posttranslational modification, protein turnover, chaperones 146318865 Common - hypothetical protein SSU05_1211 10 None None None 146319640 Common - Thioredoxin reductase SSU05_1986 247 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 146317682 Common - aromatic amino acid aminotransferase SSU05_0022 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 146319597 Common - Permease of the major facilitator superfamily SSU05_1943 10 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 146319754 Common - hypothetical protein SSU05_2100 9 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 146318704 Pathogen - hypothetical protein SSU05_1050 1 None None None 146319101 Common - Arsenate reductase and related proteins, glutaredoxin family SSU05_1447 46 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 146319475 Common - Transcription termination factor SSU05_1821 1 COG0781 NusB, Transcription termination factor Transcription 146318420 Common - Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase SSU05_0766 13 None None None 146318388 Common - Hydroxyethylthiazole kinase SSU05_0734 77 COG2145 ThiM, Hydroxyethylthiazole kinase, sugar kinase family Coenzyme metabolism 146319564 Common - Response regulator SSU05_1910 225 COG4753 COG4753, Response regulator containing CheY-like receiver domain and AraC-type DNA-binding domain Signal transduction mechanisms 146319116 Common - dipeptidase PepV SSU05_1462 137 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 146318005 Common - transcriptional repressor CodY SSU05_0350 20 COG4465 CodY, Pleiotropic transcriptional repressor Transcription 146319147 Common - Alpha-acetolactate decarboxylase SSU05_1493 40 COG3527 AlsD, Alpha-acetolactate decarboxylase Secondary metabolites biosynthesis, transport, and catabolism 146319416 Pathogen - hypothetical protein SSU05_1762 1 None None None 146319284 Common - transcriptional repressor PadR SSU05_1630 24 COG1695 COG1695, Predicted transcriptional regulators Transcription 146319711 Common - hypothetical protein SSU05_2057 5 None None None 146318350 Common - putative HsdS SSU05_0696 71 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 146318912 Common - tagatose 1,6-diphosphate aldolase SSU05_1258 25 COG3684 LacD, Tagatose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 146319812 Common - Replicative DNA helicase SSU05_2158 216 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 146317847 Common ulaA ascorbate-specific PTS system enzyme IIC SSU05_0189 36 COG3037 SgaT, Uncharacterized protein conserved in bacteria Function unknown 146319232 Pathogen - hypothetical protein SSU05_1578 1 None None None 146319063 Common - Fe2+ transport system protein B SSU05_1409 171 COG0370 FeoB, Fe2+ transport system protein B Inorganic ion transport and metabolism 146318451 Common - Predicted RNA-binding protein (contains KH domain) SSU05_0797 5 COG1837 COG1837, Predicted RNA-binding protein (contains KH domain) General function prediction only 146319849 Common dnaA chromosomal replication initiation protein SSU05_0001 213 COG0593 DnaA, ATPase involved in DNA replication initiation DNA replication, recombination, and repair 146319533 Common - undecaprenyl pyrophosphate phosphatase SSU05_1879 200 COG1968 BacA, Uncharacterized bacitracin resistance protein Defense mechanisms 146318679 Common - Helicase subunit of the DNA excision repair complex SSU05_1025 224 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 146318525 Pathogen - hypothetical protein SSU05_0871 1 None None None 146319123 Common - hypothetical protein SSU05_1469 12 COG4856 COG4856, Uncharacterized protein conserved in bacteria Function unknown 146318811 Common - mannonate dehydratase SSU05_1157 58 COG1312 UxuA, D-mannonate dehydratase Carbohydrate transport and metabolism 146318040 Pathogen - hypothetical protein SSU05_0385 1 None None None 146319211 Common - ABC-type sugar transport system, permease component SSU05_1557 146 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 146319237 Common - NTP pyrophosphohydrolase including oxidative damage repair enzymes SSU05_1583 120 COG0494 MutT, NTP pyrophosphohydrolases including oxidative damage repair enzymes DNA replication, recombination, and repair / General function prediction only 146319028 Common tgt queuine tRNA-ribosyltransferase SSU05_1374 231 COG0343 Tgt, Queuine/archaeosine tRNA-ribosyltransferase Translation, ribosomal structure and biogenesis 146318608 Common - hypothetical protein SSU05_0954 4 None None None 146319055 Common - Phosphotransferase system IIC component, glucose/maltose/N-acetylglucosamine-specific SSU05_1401 49 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 146318398 Pathogen - hypothetical protein SSU05_0744 4 None None None 146318215 Common - hypothetical protein SSU05_0561 43 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 146319208 Common - Glycosidase SSU05_1554 167 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 146319021 Common - hypothetical protein SSU05_1367 3 None None None 146318011 Common gatB aspartyl/glutamyl-tRNA amidotransferase subunit B SSU05_0356 213 COG0064 GatB, Asp-tRNAAsn/Glu-tRNAGln amidotransferase B subunit (PET112 homolog) Translation, ribosomal structure and biogenesis 146317840 Pathogen - hypothetical protein SSU05_0182 1 None None None 146319590 Pathogen - hypothetical protein SSU05_1936 1 None None None 146318251 Common - 5-enolpyruvylshikimate-3-phosphate synthase SSU05_0597 119 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 146317749 Common - Ribosomal protein L15 SSU05_0089 216 COG0200 RplO, Ribosomal protein L15 Translation, ribosomal structure and biogenesis 146319689 Common dut deoxyuridine 5'-triphosphate nucleotidohydrolase SSU05_2035 180 COG0756 Dut, dUTPase Nucleotide transport and metabolism 146318357 Common - Predicted DNA alkylation repair enzyme SSU05_0703 16 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 146318422 Common - hypothetical protein SSU05_0768 1 None None None 146318435 Common rplU 50S ribosomal protein L21 SSU05_0781 202 COG0261 RplU, Ribosomal protein L21 Translation, ribosomal structure and biogenesis 146318194 Common - ABC-type multidrug transport system, ATPase component SSU05_0540 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146318262 Common - Transcriptional regulator SSU05_0608 99 COG1846 MarR, Transcriptional regulators Transcription 146318872 Common - Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC SSU05_1218 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 146318281 Common - carbamate kinase SSU05_0627 65 COG0549 ArcC, Carbamate kinase Amino acid transport and metabolism 146318893 Common - Predicted O-methyltransferase SSU05_1239 106 COG4122 COG4122, Predicted O-methyltransferase General function prediction only 146319614 Common - Glycerol uptake facilitator and related Permease (Major Intrinsic Protein Family) SSU05_1960 133 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 146318201 Common - Lysophospholipase L1 and related esterase SSU05_0547 8 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 146317928 Common - Translation initiation factor 2 (IF-2; GTPase) SSU05_0272 96 COG5373 COG5373, Predicted membrane protein Function unknown 146318364 Common - Phosphotransferase system cellobiose-specific component IIB SSU05_0710 32 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 146319742 Pathogen - hypothetical protein SSU05_2088 1 None None None 146319298 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_1644 44 COG0456 RimI, Acetyltransferases General function prediction only 146318802 Pathogen - hypothetical protein SSU05_1148 1 None None None 146318220 Common - Cps2C SSU05_0566 200 COG0489 Mrp, ATPases involved in chromosome partitioning Cell division and chromosome partitioning 146318673 Pathogen - hypothetical protein SSU05_1019 1 None None None 146317712 Common - Predicted phosphatase SSU05_0052 108 COG0546 Gph, Predicted phosphatases General function prediction only 146317795 Common - putative folylpolyglutamate synthetase SSU05_0137 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 146317862 Common - Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) SSU05_0206 64 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 146319680 Common - amino acid permease SSU05_2026 129 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 146317832 Common - putative integral membrane protein; possible branched-chain amino acid permease SSU05_0174 110 COG1296 AzlC, Predicted branched-chain amino acid permease (azaleucine resistance) Amino acid transport and metabolism 146318684 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_1030 3 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 146319356 Common xerD site-specific tyrosine recombinase XerD-like protein SSU05_1702 4 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146317710 Common ruvB Holliday junction DNA helicase B SSU05_0050 222 COG2255 RuvB, Holliday junction resolvasome, helicase subunit DNA replication, recombination, and repair 146318533 Common - Adenylylsulfate kinase and related kinases SSU05_0879 13 COG0529 CysC, Adenylylsulfate kinase and related kinases Inorganic ion transport and metabolism 146317973 Common - hypothetical protein SSU05_0317 4 None None None 146319006 Common - D-alanine-D-alanine ligase and related ATP-grasp enzymes SSU05_1352 218 COG1181 DdlA, D-alanine-D-alanine ligase and related ATP-grasp enzymes Cell envelope biogenesis, outer membrane 146319777 Common - Mismatch repair ATPase (MutS family) SSU05_2123 206 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 146317888 Common - Transcriptional regulator SSU05_0232 109 COG2188 PhnF, Transcriptional regulators Transcription 146318349 Common - putative HsdM SSU05_0695 145 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 146318939 Common - polysaccharide biosynthesis protein SSU05_1285 13 COG3754 RgpF, Lipopolysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 146319665 Common - Mg-dependent DNase SSU05_2011 236 COG0084 TatD, Mg-dependent DNase DNA replication, recombination, and repair 146318315 Common - Thymidylate kinase SSU05_0661 233 COG0125 Tmk, Thymidylate kinase Nucleotide transport and metabolism 146318076 Common - hypothetical protein SSU05_0421 76 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 146319662 Pathogen - hypothetical protein SSU05_2008 1 None None None 146318546 Common - putative bacteroiocin operon protein SSU05_0892 4 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 146318283 Common - hypothetical protein SSU05_0629 164 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 146319791 Common - Transcriptional regulator SSU05_2137 127 COG1609 PurR, Transcriptional regulators Transcription 146318639 Common - DNA topoisomerase I SSU05_0985 247 COG0550 TopA, Topoisomerase IA DNA replication, recombination, and repair 146319221 Common - Predicted endonuclease containing a URI domain SSU05_1567 83 COG2827 COG2827, Predicted endonuclease containing a URI domain DNA replication, recombination, and repair 146318903 Common - phospho-2-dehydro-3-deoxyheptonate aldolase SSU05_1249 110 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 146319719 Common - Type II secretory pathway, pullulanase PulA and related glycosidases SSU05_2065 155 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 146317731 Common rplC 50S ribosomal protein L3 SSU05_0071 249 COG0087 RplC, Ribosomal protein L3 Translation, ribosomal structure and biogenesis 146319182 Common - Gp21 protein SSU05_1528 2 None None None 146317839 Common - ABC-type multidrug transport system, ATPase component SSU05_0181 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146318978 Common - 2-dehydropantoate 2-reductase SSU05_1324 129 COG1893 ApbA, Ketopantoate reductase Coenzyme metabolism 146319704 Common - Serine/threonine protein phosphatase SSU05_2050 105 COG0639 ApaH, Diadenosine tetraphosphatase and related serine/threonine protein phosphatases Signal transduction mechanisms 146319799 Common - glucocerebrosidase SSU05_2145 115 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 146318842 Common - Predicted hydrolase of the HAD superfamily SSU05_1188 135 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 146319454 Common - 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratase SSU05_1800 187 COG0764 FabA, 3-hydroxymyristoyl/3-hydroxydecanoyl-(acyl carrier protein) dehydratases Lipid metabolism 146319555 Common - hypothetical protein SSU05_1901 26 COG3688 COG3688, Predicted RNA-binding protein containing a PIN domain General function prediction only 146318137 Common - Predicted enzyme with a TIM-barrel fold SSU05_0482 199 COG0325 COG0325, Predicted enzyme with a TIM-barrel fold General function prediction only 146318117 Common - DNA or RNA helicase of superfamily II SSU05_0463 78 COG4951 COG4951, Uncharacterized protein conserved in bacteria Function unknown 146319459 Common - Dioxygenase related to 2-nitropropane dioxygenase SSU05_1805 136 COG2070 COG2070, Dioxygenases related to 2-nitropropane dioxygenase General function prediction only 146319581 Common - polynucleotide phosphorylase/polyadenylase SSU05_1927 233 COG1185 Pnp, Polyribonucleotide nucleotidyltransferase (polynucleotide phosphorylase) Translation, ribosomal structure and biogenesis 146319254 Common - Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) SSU05_1600 147 COG1732 OpuBC, Periplasmic glycine betaine/choline-binding (lipo)protein of an ABC-type transport system (osmoprotectant binding protein) Cell envelope biogenesis, outer membrane 146318760 Common - ABC-type phosphate transport system, periplasmic component SSU05_1106 14 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 146317828 Common - ABC-type sugar transport system, permease component SSU05_0170 144 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 146318443 Common - pyrimidine regulatory protein PyrR SSU05_0789 115 COG2065 PyrR, Pyrimidine operon attenuation protein/uracil phosphoribosyltransferase Nucleotide transport and metabolism 146319240 Pathogen - hypothetical protein SSU05_1586 1 None None None 146318719 Common - ribose-phosphate pyrophosphokinase SSU05_1065 244 COG0462 PrsA, Phosphoribosylpyrophosphate synthetase Nucleotide transport and metabolism / Amino acid transport and metabolism 146318142 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_0488 14 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 146318783 Common - Predicted membrane protein SSU05_1129 3 None None None 146319019 Common - ABC-type amino acid transport system, permease component SSU05_1365 171 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146318299 Common - Glutathione peroxidase SSU05_0645 114 COG0386 BtuE, Glutathione peroxidase Posttranslational modification, protein turnover, chaperones 146319079 Pathogen - Transposase SSU05_1425 1 None None None 146318247 Pathogen - hypothetical protein SSU05_0593 1 None None None 146319094 Pathogen - Acyl-ACP thioesterase SSU05_1440 1 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 146319541 Common ilvH acetolactate synthase 3 regulatory subunit SSU05_1887 193 COG0440 IlvH, Acetolactate synthase, small (regulatory) subunit Amino acid transport and metabolism 146319319 Common - putative manganese-dependent inorganic pyrophosphatase SSU05_1665 53 COG1227 PPX1, Inorganic pyrophosphatase/exopolyphosphatase Energy production and conversion 146318491 Common clpX ATP-dependent protease ATP-binding subunit SSU05_0837 227 COG1219 ClpX, ATP-dependent protease Clp, ATPase subunit Posttranslational modification, protein turnover, chaperones 146319247 Common - ABC transporter membrane-spanning permease - unknown substrate SSU05_1593 17 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 146318415 Common - Protein involved in cell division SSU05_0761 12 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 146318796 Common - dihydroneopterin aldolase SSU05_1142 90 COG1539 FolB, Dihydroneopterin aldolase Coenzyme metabolism 146319143 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase SSU05_1489 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 146317881 Common - Signal peptidase I SSU05_0225 150 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 146319423 Common - ABC-type metal ion transport system, ATPase component SSU05_1769 249 COG1135 AbcC, ABC-type metal ion transport system, ATPase component Inorganic ion transport and metabolism 146318444 Common pyrB aspartate carbamoyltransferase catalytic subunit SSU05_0790 236 COG0540 PyrB, Aspartate carbamoyltransferase, catalytic chain Nucleotide transport and metabolism 146317945 Common - Mevalonate kinase SSU05_0289 53 COG1577 ERG12, Mevalonate kinase Lipid metabolism 146318511 Common - hypothetical protein SSU05_0857 5 None None None 146319365 Common - hypothetical protein SSU05_1711 11 COG1418 COG1418, Predicted HD superfamily hydrolase General function prediction only 146319340 Common - putative sensor histidine kinase SSU05_1686 96 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 146319507 Pathogen - hypothetical protein SSU05_1853 1 None None None 146319328 Common - Glycopeptide antibiotics resistance protein SSU05_1674 2 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 146318356 Common - Predicted DNA alkylation repair enzyme SSU05_0702 10 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 146319010 Common - ABC transporter, ATP-binding protein SSU05_1356 238 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 146318824 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase SSU05_1170 211 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 146319262 Common - Transposase and inactivated derivative SSU05_1608 12 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318572 Pathogen - hypothetical protein SSU05_0918 2 None None None 146318723 Common - redox-sensing transcriptional repressor Rex SSU05_1069 56 COG2344 COG2344, AT-rich DNA-binding protein General function prediction only 146318619 Common - agglutinin receptor SSU05_0965 23 COG3064 TolA, Membrane protein involved in colicin uptake Cell envelope biogenesis, outer membrane 146318080 Common fmt methionyl-tRNA formyltransferase SSU05_0425 215 COG0223 Fmt, Methionyl-tRNA formyltransferase Translation, ribosomal structure and biogenesis 146318497 Pathogen - hypothetical protein SSU05_0843 1 None None None 146318579 Common - hypothetical protein SSU05_0925 7 COG4372 COG4372, Uncharacterized protein conserved in bacteria with the myosin-like domain Function unknown 146317742 Common rplX 50S ribosomal protein L24 SSU05_0082 213 COG0198 RplX, Ribosomal protein L24 Translation, ribosomal structure and biogenesis 146318857 Pathogen - hypothetical protein SSU05_1203 1 None None None 146318045 Common - ATPases with chaperone activity, ATP-binding subunit SSU05_0390 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 146318561 Common - NisR SSU05_0907 218 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146319070 Common - Predicted membrane protein SSU05_1416 3 None None None 146319847 Common - Predicted transcriptional regulator SSU05_2193 187 COG1475 Spo0J, Predicted transcriptional regulators Transcription 146318094 Common - Ribosome-associated protein Y (PSrp-1) SSU05_0439 172 COG1544 COG1544, Ribosome-associated protein Y (PSrp-1) Translation, ribosomal structure and biogenesis 146318672 Common - putative amino acid transporter, amino acid-binding protein SSU05_1018 179 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146318838 Common - glucose-6-phosphate 1-dehydrogenase SSU05_1184 159 COG0364 Zwf, Glucose-6-phosphate 1-dehydrogenase Carbohydrate transport and metabolism 146318210 Common - Rad3-related DNA helicase SSU05_0556 176 COG1199 DinG, Rad3-related DNA helicases Transcription / DNA replication, recombination, and repair 146319586 Common - glucokinase regulatory protein SSU05_1932 83 COG2103 COG2103, Predicted sugar phosphate isomerase General function prediction only 146319336 Common - extracellular serine protease SSU05_1682 2 None None None 146318727 Common - putative DNA repair protein SSU05_1073 4 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 146318571 Common - Tn916, transposase SSU05_0917 166 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146319311 Common - Predicted metalloprotease SSU05_1657 86 COG2321 COG2321, Predicted metalloprotease General function prediction only 146319030 Common - Predicted CoA-binding protein SSU05_1376 129 COG1832 COG1832, Predicted CoA-binding protein General function prediction only 146318578 Common - hypothetical protein SSU05_0924 132 COG0791 Spr, Cell wall-associated hydrolases (invasion-associated proteins) Cell envelope biogenesis, outer membrane 146319695 Common - glucose-1-phosphate-uridylyltransferase SSU05_2041 233 COG1210 GalU, UDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 146318179 Common - hypothetical protein SSU05_0525 4 None None None 146318938 Common - polysaccharide/teichoic acid transporter, putative SSU05_1284 4 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 146317996 Common rpmB 50S ribosomal protein L28 SSU05_0340 79 COG0227 RpmB, Ribosomal protein L28 Translation, ribosomal structure and biogenesis 146317890 Common - Uncharacterized membrane protein, required for colicin V production SSU05_0234 10 COG1286 CvpA, Uncharacterized membrane protein, required for colicin V production General function prediction only 146319154 Common - Cytotoxic translational repressor of toxin-antitoxin stability system SSU05_1500 30 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 146318551 Common - hypothetical protein SSU05_0897 15 COG4947 COG4947, Uncharacterized protein conserved in bacteria Function unknown 146319557 Pathogen - hypothetical protein SSU05_1903 1 COG2815 COG2815, Uncharacterized protein conserved in bacteria Function unknown 146318010 Common gatA aspartyl/glutamyl-tRNA amidotransferase subunit A SSU05_0355 222 COG0154 GatA, Asp-tRNAAsn/Glu-tRNAGln amidotransferase A subunit and related amidases Translation, ribosomal structure and biogenesis 146319139 Common - ABC-type uncharacterized transport system, ATPase component SSU05_1485 84 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 146318892 Common - Parvulin-like peptidyl-prolyl isomerase SSU05_1238 12 COG0760 SurA, Parvulin-like peptidyl-prolyl isomerase Posttranslational modification, protein turnover, chaperones 146318408 Common - ATP-dependent nuclease, subunit B SSU05_0754 23 COG3857 AddB, ATP-dependent nuclease, subunit B DNA replication, recombination, and repair 146318320 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_0666 17 None None None 146318060 Pathogen - hypothetical protein SSU05_0405 1 None None None 146318184 Common - elongation factor Tu SSU05_0530 249 COG0050 TufB, GTPases - translation elongation factors Translation, ribosomal structure and biogenesis 146319294 Common - Acetyl-CoA acetyltransferase SSU05_1640 185 COG0183 PaaJ, Acetyl-CoA acetyltransferase Lipid metabolism 146319331 Common - Predicted Fe-S-cluster redox enzyme SSU05_1677 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 146319392 Common - hypothetical protein SSU05_1738 1 None None None 146319274 Common - Putative NADPH-quinone reductase (modulator of drug activity B) SSU05_1620 74 COG2249 MdaB, Putative NADPH-quinone reductase (modulator of drug activity B) General function prediction only 146318363 Common - Phosphotransferase system cellobiose-specific component IIA SSU05_0709 31 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 146319737 Common - zinc ABC transporter, permease protein SSU05_2083 112 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 146317674 Common - Beta-lactamase class A SSU05_0012 18 COG2367 PenP, Beta-lactamase class A Defense mechanisms 146318401 Common - Predicted permease SSU05_0747 3 None None None 146319604 Common - Predicted membrane protein SSU05_1950 11 COG2261 COG2261, Predicted membrane protein Function unknown 146318501 Common - Thymidine kinase SSU05_0847 79 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 146319150 Common - Predicted permease SSU05_1496 212 COG0628 PerM, Predicted permease General function prediction only 146318931 Common - Glycosyltransferases involved in cell wall biogenesis SSU05_1277 175 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146318959 Common - Putative primosome component and related proteins SSU05_1305 17 COG3935 DnaD, Putative primosome component and related proteins DNA replication, recombination, and repair 146317914 Common - ABC-type uncharacterized transport system, ATPase component SSU05_0258 249 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 146318232 Common - Sialic acid synthase SSU05_0578 78 COG2089 SpsE, Sialic acid synthase Cell envelope biogenesis, outer membrane 146318940 Common - ABC-type polysaccharide/polyol phosphate transport system, ATPase component SSU05_1286 249 COG1134 TagH, ABC-type polysaccharide/polyol phosphate transport system, ATPase component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 146318649 Common - hypothetical protein SSU05_0995 83 COG1434 COG1434, Uncharacterized conserved protein Function unknown 146319668 Common - hypothetical protein SSU05_2014 193 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 146318263 Pathogen - Transposase and inactivated derivative SSU05_0609 3 None None None 146319399 Common - Predicted transcriptional regulator SSU05_1745 51 COG1476 COG1476, Predicted transcriptional regulators Transcription 146319731 Common - hypothetical protein SSU05_2077 17 COG3589 COG3589, Uncharacterized conserved protein Function unknown 146319174 Pathogen - unknown phage protein SSU05_1520 1 None None None 146318976 Common - hypothetical protein SSU05_1322 8 COG4479 COG4479, Uncharacterized protein conserved in bacteria Function unknown 146319437 Common - Seryl-tRNA synthetase SSU05_1783 53 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 146319404 Pathogen - hypothetical protein SSU05_1750 1 None None None 146319756 Common - LPXTG-motif cell wall anchor domain protein SSU05_2103 12 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 146319643 Common - Predicted aminoglycoside phosphotransferase SSU05_1989 12 COG3173 COG3173, Predicted aminoglycoside phosphotransferase General function prediction only 146318789 Common - Predicted membrane protein SSU05_1135 31 COG3759 COG3759, Predicted membrane protein Function unknown 146319751 Common - sortase-like protein SSU05_2097 19 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 146318374 Common - oxidoreductase, pyridine nucleotide-disulfide family SSU05_0720 230 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 146319629 Common - ATPases with chaperone activity, ATP-binding subunit SSU05_1975 221 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 146319809 Common - Thiol-disulfide isomerase and thioredoxin SSU05_2155 4 None None None 146317685 Common - Acyl carrier protein SSU05_0025 108 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146318019 Pathogen - hypothetical protein SSU05_0364 1 None None None 146318686 Common - ATPase component of ABC transporters with duplicated ATPase domains SSU05_1031 207 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 146319515 Common - Predicted kinase related to dihydroxyacetone kinase SSU05_1861 50 COG1461 COG1461, Predicted kinase related to dihydroxyacetone kinase General function prediction only 146319446 Common - hypothetical protein SSU05_1792 22 None None None 146318107 Common - Phosphotransferase system, mannose/fructose-specific component IIA SSU05_0453 65 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 146318002 Common - hypothetical protein SSU05_0347 6 COG4696 COG4696, Uncharacterized protein conserved in bacteria Function unknown 146317692 Common purH bifunctional phosphoribosylaminoimidazolecarboxamide formyltransferase/IMP cyclohydrolase SSU05_0032 219 COG0138 PurH, AICAR transformylase/IMP cyclohydrolase PurH (only IMP cyclohydrolase domain in Aful) Nucleotide transport and metabolism 146317718 Common - Heme/copper-type cytochrome/quinol oxidase, subunit 1 SSU05_0058 2 COG1807 ArnT, 4-amino-4-deoxy-L-arabinose transferase and related glycosyltransferases of PMT family Cell envelope biogenesis, outer membrane 146318031 Common - hypothetical protein SSU05_0376 14 None None None 146318618 Common - hypothetical protein SSU05_0964 10 None None None 146318992 Common - ABC-type sugar transport system, periplasmic component SSU05_1338 16 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 146317770 Common - ABC-type metal ion transport system, periplasmic component/surface adhesin SSU05_0112 175 COG3443 COG3443, Predicted periplasmic or secreted protein General function prediction only 146319045 Common - Exoribonuclease R SSU05_1391 192 COG0557 VacB, Exoribonuclease R Transcription 146318138 Common - hypothetical protein SSU05_0484 16 COG1799 COG1799, Uncharacterized protein conserved in bacteria Function unknown 146318597 Common - DNA-binding response regulator, putative SSU05_0943 172 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146319317 Common - Methyl-accepting chemotaxis protein SSU05_1663 30 None None None 146319493 Common - branched-chain alpha-keto acid dehydrogenase subunit E2 SSU05_1839 195 COG0508 AceF, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide acyltransferase (E2) component, and related enzymes Energy production and conversion 146318702 Common - Integrase SSU05_1048 17 None None None 146317743 Common rplE 50S ribosomal protein L5 SSU05_0083 249 COG0094 RplE, Ribosomal protein L5 Translation, ribosomal structure and biogenesis 146319095 Common - coproporphyrinogen III oxidase SSU05_1441 208 COG0635 HemN, Coproporphyrinogen III oxidase and related Fe-S oxidoreductases Coenzyme metabolism 146318621 Common - hypothetical protein SSU05_0967 22 COG2253 COG2253, Uncharacterized conserved protein Function unknown 146318730 Common ldh L-lactate dehydrogenase SSU05_1076 166 COG0039 Mdh, Malate/lactate dehydrogenases Energy production and conversion 146318469 Common - guanosine 5'-monophosphate oxidoreductase SSU05_0815 233 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 146317899 Pathogen - hypothetical protein SSU05_0243 1 COG4652 COG4652, Uncharacterized protein conserved in bacteria Function unknown 146319068 Common - Uncharacterized Fe-S protein SSU05_1414 140 COG1600 COG1600, Uncharacterized Fe-S protein Energy production and conversion 146319379 Pathogen - Permease of the major facilitator superfamily SSU05_1725 1 None None None 146317999 Common - L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D SSU05_0344 43 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 146319071 Pathogen - hypothetical protein SSU05_1417 1 None None None 146318183 Common - hypothetical protein SSU05_0529 6 None None None 146318949 Pathogen - hypothetical protein SSU05_1295 1 None None None 146319663 Pathogen - hypothetical protein SSU05_2009 1 None None None 146319651 Common - Predicted transcriptional regulator SSU05_1997 7 None None None 146318987 Common - hypothetical protein SSU05_1333 3 None None None 146317705 Common - ABC-type multidrug transport system, ATPase component SSU05_0045 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146318067 Common gidB glucose-inhibited division protein B SSU05_0412 186 COG0357 GidB, Predicted S-adenosylmethionine-dependent methyltransferase involved in bacterial cell division Cell envelope biogenesis, outer membrane 146319782 Pathogen - Permease of the major facilitator superfamily SSU05_2128 1 None None None 146317856 Common - Pyruvate-formate lyase SSU05_0200 55 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 146319462 Common - Transcriptional regulator SSU05_1808 69 COG1846 MarR, Transcriptional regulators Transcription 146319364 Common - putative integral membrane protein SSU05_1710 111 COG0670 COG0670, Integral membrane protein, interacts with FtsH General function prediction only 146319132 Common - Predicted Zn-dependent protease SSU05_1478 2 COG5549 COG5549, Predicted Zn-dependent protease Posttranslational modification, protein turnover, chaperones 146317814 Pathogen - hypothetical protein SSU05_0156 1 None None None 146318009 Common gatC aspartyl/glutamyl-tRNA amidotransferase subunit C SSU05_0354 143 COG0721 GatC, Asp-tRNAAsn/Glu-tRNAGln amidotransferase C subunit Translation, ribosomal structure and biogenesis 146317880 Common - ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member SSU05_0224 137 COG0507 RecD, ATP-dependent exoDNAse (exonuclease V), alpha subunit - helicase superfamily I member DNA replication, recombination, and repair 146318655 Pathogen - hypothetical protein SSU05_1001 1 None None None 146318290 Pathogen - hypothetical protein SSU05_0637 1 None None None 146318380 Pathogen - hypothetical protein SSU05_0726 1 None None None 146318514 Common - GTPase subunit of restriction endonuclease SSU05_0860 52 COG1401 McrB, GTPase subunit of restriction endonuclease Defense mechanisms 146317905 Common - Na+/alanine symporter SSU05_0249 114 COG1115 AlsT, Na+/alanine symporter Amino acid transport and metabolism 146318127 Common - Ribonucleases G and E SSU05_0473 14 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 146319350 Pathogen - hypothetical protein SSU05_1695 1 None None None 146319674 Common - Predicted small molecule binding protein (contains 3H domain) SSU05_2020 15 COG1827 COG1827, Predicted small molecule binding protein (contains 3H domain) General function prediction only 146318690 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase SSU05_1036 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 146318908 Common - ABC-type uncharacterized transport system, permease component SSU05_1254 51 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 146318759 Common - ABC-type phosphate transport system, periplasmic component SSU05_1105 96 COG0226 PstS, ABC-type phosphate transport system, periplasmic component Inorganic ion transport and metabolism 146318638 Common - Ribosomal protein L10 SSU05_0984 210 COG0244 RplJ, Ribosomal protein L10 Translation, ribosomal structure and biogenesis 146318738 Common - cytidine deaminase SSU05_1084 116 COG0295 Cdd, Cytidine deaminase Nucleotide transport and metabolism 146318103 Common - Beta-galactosidase SSU05_0449 24 COG1874 LacA, Beta-galactosidase Carbohydrate transport and metabolism 146317971 Pathogen - hypothetical protein SSU05_0316 1 None None None 146319114 Common - Uracil-DNA glycosylase SSU05_1460 56 COG1573 COG1573, Uracil-DNA glycosylase DNA replication, recombination, and repair 146318746 Pathogen - hypothetical protein SSU05_1092 1 None None None 146318021 Common - Predicted GTPase SSU05_0366 22 COG1161 COG1161, Predicted GTPases General function prediction only 146318523 Pathogen - hypothetical protein SSU05_0869 1 None None None 146319192 Common - putative 5'-nucleotidase SSU05_1538 115 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 146317932 Common rpmG 50S ribosomal protein L33 SSU05_0276 79 COG0267 RpmG, Ribosomal protein L33 Translation, ribosomal structure and biogenesis 146319467 Common acpS 4'-phosphopantetheinyl transferase SSU05_1813 102 COG0736 AcpS, Phosphopantetheinyl transferase (holo-ACP synthase) Lipid metabolism 146317767 Common - Transcriptional regulator SSU05_0109 4 COG1846 MarR, Transcriptional regulators Transcription 146318165 Common - hypothetical protein SSU05_0511 244 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 146317845 Common - Transcriptional antiterminator SSU05_0187 52 COG3711 BglG, Transcriptional antiterminator Transcription 146317804 Pathogen - hypothetical protein SSU05_0146 2 None None None 146318795 Common - putative 2-amino-4-hydroxy-6-hydroxymethylpteridine pyrophosphokinase SSU05_1141 202 COG0801 FolK, 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase Coenzyme metabolism 146319300 Common - Transposase and inactivated derivative SSU05_1646 66 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318387 Common - phosphomethylpyrimidine kinase SSU05_0733 220 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 146317961 Common - ABC-type amino acid transport/signal transduction system, periplasmic component/domain SSU05_0305 136 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146317981 Common - lipase SSU05_0325 7 COG4188 COG4188, Predicted dienelactone hydrolase General function prediction only 146318991 Common - Beta-fructosidases (levanase/invertase) SSU05_1337 54 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 146319819 Pathogen - hypothetical protein SSU05_2165 1 None None None 146319805 Pathogen - Predicted phosphohydrolase SSU05_2151 1 None None None 146319230 Common - Superfamily I DNA and RNA helicase SSU05_1576 29 None None None 146319124 Common - hypothetical protein SSU05_1470 67 COG1624 COG1624, Uncharacterized conserved protein Function unknown 146318506 Common glyA serine hydroxymethyltransferase SSU05_0852 245 COG0112 GlyA, Glycine/serine hydroxymethyltransferase Amino acid transport and metabolism 146319281 Common - DNA polymerase III subunits gamma and tau SSU05_1627 248 COG2812 DnaX, DNA polymerase III, gamma/tau subunits DNA replication, recombination, and repair 146317809 Common - 30S ribosomal protein S7 SSU05_0151 247 COG0049 RpsG, Ribosomal protein S7 Translation, ribosomal structure and biogenesis 146319348 Common - Membrane-associated phospholipid phosphatase SSU05_1694 48 COG0671 PgpB, Membrane-associated phospholipid phosphatase Lipid metabolism 146318812 Common - Glucuronate isomerase SSU05_1158 57 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 146319035 Common - ABC-type antimicrobial peptide transport system, ATPase component SSU05_1381 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 146318112 Common - Shikimate kinase SSU05_0458 5 None None None 146317922 Common - Putative effector of murein hydrolase SSU05_0266 71 COG1346 LrgB, Putative effector of murein hydrolase Cell envelope biogenesis, outer membrane 146319353 Common - 16S rRNA uridine-516 pseudouridylate synthase and related Pseudouridylate synthase SSU05_1699 207 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 146319574 Common - hypothetical protein SSU05_1920 19 COG3538 COG3538, Uncharacterized conserved protein Function unknown 146318670 Common - 1,4-alpha-glucan branching enzyme SSU05_1016 144 COG0296 GlgB, 1,4-alpha-glucan branching enzyme Carbohydrate transport and metabolism 146319335 Common - hypothetical protein SSU05_1681 212 COG0742 COG0742, N6-adenine-specific methylase DNA replication, recombination, and repair 146318128 Common - Autotransporter adhesin SSU05_0474 10 None None None 146318563 Pathogen - hypothetical protein SSU05_0909 1 None None None 146319562 Pathogen - hypothetical protein SSU05_1908 1 None None None 146318585 Common - hypothetical protein SSU05_0931 99 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 146318212 Common proA gamma-glutamyl phosphate reductase SSU05_0558 192 COG0014 ProA, Gamma-glutamyl phosphate reductase Amino acid transport and metabolism 146319631 Common - putative bacterocin transport accessory protein, Bta SSU05_1977 3 None None None 146319841 Common - ATPase component of ABC transporters with duplicated ATPase domains SSU05_2187 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 146318145 Common - putative hydrolase (MutT family) SSU05_0491 19 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146318774 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_1120 6 None None None 146318078 Common - DNA-directed RNA polymerase subunit omega SSU05_0423 12 COG1758 RpoZ, DNA-directed RNA polymerase, subunit K/omega Transcription 146317823 Common - Acetyltransferase SSU05_0165 157 COG0456 RimI, Acetyltransferases General function prediction only 146319584 Common - outer surface protein SSU05_1930 16 COG3589 COG3589, Uncharacterized conserved protein Function unknown 146319000 Common - Peptide chain release factor RF-3 SSU05_1346 245 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 146319526 Pathogen - hypothetical protein SSU05_1872 1 None None None 146318867 Common - hyaluronidase SSU05_1213 11 None None None 146318567 Common - Chromosome segregation ATPase SSU05_0913 10 COG3843 VirD2, Type IV secretory pathway, VirD2 components (relaxase) Intracellular trafficking and secretion 146319145 Common - Transcriptional antiterminator SSU05_1491 29 COG3711 BglG, Transcriptional antiterminator Transcription 146318096 Pathogen - hypothetical protein SSU05_0442 1 None None None 146317900 Pathogen - hypothetical protein SSU05_0244 1 None None None 146318905 Common aroE shikimate 5-dehydrogenase SSU05_1251 225 COG0169 AroE, Shikimate 5-dehydrogenase Amino acid transport and metabolism 146318111 Common - Lactoylglutathione lyase and related lyases SSU05_0457 7 COG2514 COG2514, Predicted ring-cleavage extradiol dioxygenase General function prediction only 146317897 Common - transcriptional regulator PlcR, putative SSU05_0241 7 COG1396 HipB, Predicted transcriptional regulators Transcription 146319149 Common - TPR repeat protein SSU05_1495 21 None None None 146318677 Common - hypothetical protein SSU05_1023 4 None None None 146318173 Common lysS lysyl-tRNA synthetase SSU05_0519 248 COG1190 LysU, Lysyl-tRNA synthetase (class II) Translation, ribosomal structure and biogenesis 146319017 Common - amino acid ABC transporter, permease protein SSU05_1363 133 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146319077 Common - Transposase SSU05_1423 26 COG5433 COG5433, Transposase DNA replication, recombination, and repair 146317833 Common - hypothetical protein SSU05_0175 19 COG4392 COG4392, Predicted membrane protein Function unknown 146318884 Pathogen - hypothetical protein SSU05_1230 1 None None None 146318278 Common - arginine deiminase SSU05_0624 56 COG2235 ArcA, Arginine deiminase Amino acid transport and metabolism 146319452 Common - Acetyl-CoA carboxylase beta subunit SSU05_1798 96 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 146319429 Common - 5,10-methylenetetrahydrofolate reductase SSU05_1775 150 COG0685 MetF, 5,10-methylenetetrahydrofolate reductase Amino acid transport and metabolism 146318228 Common - Glycosyltransferases involved in cell wall biogenesis SSU05_0574 219 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146318710 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_1056 247 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146319617 Common - CDP-diglyceride synthetase SSU05_1963 215 COG0575 CdsA, CDP-diglyceride synthetase Lipid metabolism 146319765 Common - hypothetical protein SSU05_2111 4 None None None 146319366 Common - rRNA methylase SSU05_1713 209 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 146318494 Common - hypothetical protein SSU05_0840 2 None None None 146318412 Common - Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit SSU05_0758 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 146318303 Pathogen - hypothetical protein SSU05_0648 1 None None None 146319245 Pathogen - hypothetical protein SSU05_1591 1 None None None 146319820 Common - MutT/NudX family protein (putative) SSU05_2166 17 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146318236 Common - Transposase and inactivated derivative, IS5 family SSU05_0582 37 COG3039 COG3039, Transposase and inactivated derivatives, IS5 family DNA replication, recombination, and repair 146318785 Common - Predicted transcriptional regulator SSU05_1131 59 COG1695 COG1695, Predicted transcriptional regulators Transcription 146317670 Common - Transcription-repair coupling factor (superfamily II helicase) SSU05_0008 232 COG1197 Mfd, Transcription-repair coupling factor (superfamily II helicase) DNA replication, recombination, and repair / Transcription 146317745 Common rplF 50S ribosomal protein L6 SSU05_0085 241 COG0097 RplF, Ribosomal protein L6P/L9E Translation, ribosomal structure and biogenesis 146319637 Common nusG transcription antitermination protein NusG SSU05_1983 215 COG0250 NusG, Transcription antiterminator Transcription 146318499 Pathogen - hypothetical protein SSU05_0845 1 None None None 146318171 Common - ABC-type antimicrobial peptide transport system, permease component SSU05_0517 213 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 146318209 Common - Zn-dependent hydrolase, including glyoxylases SSU05_0555 191 COG0491 GloB, Zn-dependent hydrolases, including glyoxylases General function prediction only 146318271 Pathogen - hypothetical protein SSU05_0617 1 None None None 146318534 Common - hypothetical protein SSU05_0880 9 COG4823 AbiF, Abortive infection bacteriophage resistance protein Defense mechanisms 146319677 Common - NTP pyrophosphohydrolase including oxidative damage repair enzymes SSU05_2022 8 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146319797 Common - Predicted oxidoreductase SSU05_2143 191 COG4989 COG4989, Predicted oxidoreductase General function prediction only 146319648 Common - ribosome-associated GTPase SSU05_1994 163 COG1162 COG1162, Predicted GTPases General function prediction only 146319778 Common - Mismatch repair ATPase (MutS family) SSU05_2124 190 COG0249 MutS, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 146318249 Pathogen - ATPase involved in DNA repair SSU05_0595 1 None None None 146318047 Common - 4-alpha-glucanotransferase SSU05_0392 77 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 146318969 Common - GTPase SSU05_1315 212 COG2262 HflX, GTPases General function prediction only 146318159 Common - Collagenase and related protease SSU05_0505 113 COG0826 COG0826, Collagenase and related proteases Posttranslational modification, protein turnover, chaperones 146318332 Common - Predicted metal-dependent membrane protease SSU05_0678 30 None None None 146318354 Common - ATPase (PilT family) SSU05_0700 2 None None None 146317683 Common - Recombinational DNA repair protein (RecF pathway) SSU05_0023 35 COG1381 RecO, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 146319723 Common - ABC-type amino acid transport/signal transduction system, periplasmic component/domain SSU05_2069 185 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146318056 Common - Predicted transcriptional regulator SSU05_0401 17 COG1695 COG1695, Predicted transcriptional regulators Transcription 146318707 Common - Uncharacterized protein, possibly involved in aromatic compounds catabolism SSU05_1053 45 COG2050 PaaI, Uncharacterized protein, possibly involved in aromatic compounds catabolism Secondary metabolites biosynthesis, transport, and catabolism 146318433 Pathogen - Branched-chain amino acid permease SSU05_0779 1 None None None 146319180 Pathogen - Predicted transcriptional regulator SSU05_1526 1 None None None 146318285 Common - Arginine repressor SSU05_0631 55 COG1438 ArgR, Arginine repressor Transcription 146318329 Common - Amino acid transporter SSU05_0675 172 COG0531 PotE, Amino acid transporters Amino acid transport and metabolism 146318761 Common - rRNA methyltransferase, putative SSU05_1107 207 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 146319612 Common - Dihydroxyacetone kinase SSU05_1958 76 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 146318804 Common pheT phenylalanyl-tRNA synthetase subunit beta SSU05_1150 245 COG0072 PheT, Phenylalanyl-tRNA synthetase beta subunit Translation, ribosomal structure and biogenesis 146317734 Common rplB 50S ribosomal protein L2 SSU05_0074 248 COG0090 RplB, Ribosomal protein L2 Translation, ribosomal structure and biogenesis 146318348 Common - putative HsdM SSU05_0694 66 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 146319100 Common - Purine nucleoside phosphorylase SSU05_1446 110 COG0005 Pnp, Purine nucleoside phosphorylase Nucleotide transport and metabolism 146318312 Common - Uncharacterized protein involved in tellurite resistance SSU05_0658 17 COG3853 TelA, Uncharacterized protein involved in tellurite resistance Inorganic ion transport and metabolism 146317864 Common - Uncharacterized protein related to Endonuclease III SSU05_0208 115 COG2231 COG2231, Uncharacterized protein related to Endonuclease III DNA replication, recombination, and repair 146317959 Common - Lipoate-protein ligase A SSU05_0303 20 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 146319539 Common - threonine dehydratase SSU05_1885 228 COG1171 IlvA, Threonine dehydratase Amino acid transport and metabolism 146318602 Common - cytolysin B transport protein SSU05_0948 49 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 146318922 Common rplT 50S ribosomal protein L20 SSU05_1268 213 COG0292 RplT, Ribosomal protein L20 Translation, ribosomal structure and biogenesis 146319513 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_1859 61 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 146319189 Common - 30S ribosomal protein S14 SSU05_1535 200 COG0199 RpsN, Ribosomal protein S14 Translation, ribosomal structure and biogenesis 146319748 Common - GTP pyrophosphokinase SSU05_2094 206 COG0317 SpoT, Guanosine polyphosphate pyrophosphohydrolases/synthetases Signal transduction mechanisms / Transcription 146318544 Common - ABC-type antimicrobial peptide transport system, permease component SSU05_0890 12 None None None 146319592 Pathogen - hypothetical protein SSU05_1938 1 None None None 146319389 Common - 6-phosphogluconate dehydrogenase SSU05_1735 166 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 146319287 Pathogen - Predicted dehydrogenase and related proteins SSU05_1633 1 None None None 146318663 Common - orotidine 5'-phosphate decarboxylase SSU05_1009 169 COG0284 PyrF, Orotidine-5'-phosphate decarboxylase Nucleotide transport and metabolism 146317886 Common - Glycosidase SSU05_0230 163 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 146319733 Common - Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases SSU05_2079 52 COG1486 CelF, Alpha-galactosidases/6-phospho-beta-glucosidases, family 4 of glycosyl hydrolases Carbohydrate transport and metabolism 146319550 Pathogen - hypothetical protein SSU05_1896 1 COG3871 COG3871, Uncharacterized stress protein (general stress protein 26) General function prediction only 146317669 Common - peptidyl-tRNA hydrolase SSU05_0007 216 COG0193 Pth, Peptidyl-tRNA hydrolase Translation, ribosomal structure and biogenesis 146318792 Common - putative cation efflux transporter SSU05_1138 208 COG0053 MMT1, Predicted Co/Zn/Cd cation transporters Inorganic ion transport and metabolism 146319544 Common - Glycosyltransferases involved in cell wall biogenesis SSU05_1890 117 COG2246 COG2246, Predicted membrane protein Function unknown 146319569 Common - ABC transporter membrane spanning permease - sugar transport SSU05_1915 140 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 146319093 Common - Acyl-ACP thioesterase SSU05_1439 10 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 146319243 Common - hypothetical protein SSU05_1589 4 None None None 146319306 Common - Arginine repressor SSU05_1652 51 COG1438 ArgR, Arginine repressor Transcription 146319127 Common - SAM-dependent methyltransferase SSU05_1473 66 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146319201 Common - Branched-chain amino acid ABC-type transport system, permease component SSU05_1547 151 COG0559 LivH, Branched-chain amino acid ABC-type transport system, permease components Amino acid transport and metabolism 146318441 Common - hypothetical protein SSU05_0787 1 None None None 146319530 Common - ABC-type transport system involved in Fe-S cluster assembly, ATPase component SSU05_1876 249 COG0396 SufC, ABC-type transport system involved in Fe-S cluster assembly, ATPase component Posttranslational modification, protein turnover, chaperones 146318042 Pathogen - hypothetical protein SSU05_0387 1 None None None 146319410 Common - Geranylgeranyl pyrophosphate synthase SSU05_1756 230 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 146318855 Common - Phosphotransferase system, HPr-related proteins SSU05_1201 117 COG1925 FruB, Phosphotransferase system, HPr-related proteins Carbohydrate transport and metabolism 146318590 Common - Signal recognition particle GTPase SSU05_0936 16 COG4185 COG4185, Uncharacterized protein conserved in bacteria Function unknown 146319713 Common - putative L-xylulose 5-phosphate 3-epimerase SSU05_2059 36 COG3623 SgaU, Putative L-xylulose-5-phosphate 3-epimerase Carbohydrate transport and metabolism 146318217 Common - hypothetical protein SSU05_0563 68 COG3022 COG3022, Uncharacterized protein conserved in bacteria Function unknown 146318540 Common - Cytotoxic translational repressor of toxin-antitoxin stability system SSU05_0886 20 COG2026 RelE, Cytotoxic translational repressor of toxin-antitoxin stability system Translation, ribosomal structure and biogenesis / Cell division and chromosome partitioning 146318258 Common - hypothetical protein SSU05_0604 2 None None None 146318012 Common - deoxyguanosinetriphosphate triphosphohydrolase-related protein SSU05_0357 157 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 146318242 Common - Transposase and inactivated derivative SSU05_0588 55 None None None 146318576 Common - Translation elongation factor (GTPases) SSU05_0922 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 146319503 Common nusA transcription elongation factor NusA SSU05_1849 217 COG0195 NusA, Transcription elongation factor Transcription 146318038 Pathogen - hypothetical protein SSU05_0384 1 None None None 146319212 Common - ABC-type sugar transport system, periplasmic component SSU05_1558 84 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 146317758 Common - hypothetical protein SSU05_0100 138 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146319435 Common - ManO SSU05_1781 10 COG4687 COG4687, Uncharacterized protein conserved in bacteria Function unknown 146318474 Common trmD tRNA (guanine-N(1)-)-methyltransferase SSU05_0820 215 COG0336 TrmD, tRNA-(guanine-N1)-methyltransferase Translation, ribosomal structure and biogenesis 146318168 Common - ABC-type antimicrobial peptide transport system, ATPase component SSU05_0514 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 146319228 Common - Superfamily II DNA and RNA helicase SSU05_1574 240 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 146318832 Common - F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K SSU05_1178 3 COG0636 AtpE, F0F1-type ATP synthase, subunit c/Archaeal/vacuolar-type H+-ATPase, subunit K Energy production and conversion 146318837 Common - Predicted membrane protein SSU05_1183 12 COG3689 COG3689, Predicted membrane protein Function unknown 146318341 Common - Predicted membrane protein SSU05_0687 9 COG4684 COG4684, Predicted membrane protein Function unknown 146319814 Common rplI 50S ribosomal protein L9 SSU05_2160 191 COG0359 RplI, Ribosomal protein L9 Translation, ribosomal structure and biogenesis 146318234 Common - Acetyltransferase (isoleucine patch superfamily) SSU05_0580 94 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 146317798 Common - Thiol-disulfide isomerase and thioredoxin SSU05_0140 45 COG0526 TrxA, Thiol-disulfide isomerase and thioredoxins Posttranslational modification, protein turnover, chaperones / Energy production and conversion 146319026 Common - Transcriptional regulator SSU05_1372 123 COG1609 PurR, Transcriptional regulators Transcription 146319687 Common - DNA repair protein RadA SSU05_2033 210 COG1066 Sms, Predicted ATP-dependent serine protease Posttranslational modification, protein turnover, chaperones 146319214 Common - AraC-type DNA-binding domain-containing protein SSU05_1559 142 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146319740 Common - High-affinity zinc uptake system protein znuA precursor SSU05_2086 158 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 146318644 Common - hypothetical protein SSU05_0990 106 COG1937 COG1937, Uncharacterized protein conserved in bacteria Function unknown 146319829 Common - ABC-type cobalt transport system, ATPase component SSU05_2175 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 146319113 Common - Beta-propeller domains of methanol dehydrogenase type SSU05_1459 59 COG1512 COG1512, Beta-propeller domains of methanol dehydrogenase type General function prediction only 146319758 Common - hypothetical protein SSU05_2104 4 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 146319390 Common - YlbN-like hypothetical protein SSU05_1736 11 COG1399 COG1399, Predicted metal-binding, possibly nucleic acid-binding protein General function prediction only 146317910 Common - hypothetical protein SSU05_0254 69 COG2843 PgsA, Putative enzyme of poly-gamma-glutamate biosynthesis (capsule formation) Cell envelope biogenesis, outer membrane 146319602 Common - 3-isopropylmalate dehydrogenase SSU05_1948 222 COG0473 LeuB, Isocitrate/isopropylmalate dehydrogenase Amino acid transport and metabolism 146318779 Pathogen - hypothetical protein SSU05_1125 1 None None None 146318776 Common - IS630-Spn1, transposase Orf2 SSU05_1122 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318023 Common - Predicted RNA-binding protein containing KH domain, possibly ribosomal protein SSU05_0368 96 COG1534 COG1534, Predicted RNA-binding protein containing KH domain, possibly ribosomal protein Translation, ribosomal structure and biogenesis 146318954 Common - dTDP-4-dehydrorhamnose 3,5-epimerase SSU05_1300 150 COG1898 RfbC, dTDP-4-dehydrorhamnose 3,5-epimerase and related enzymes Cell envelope biogenesis, outer membrane 146319767 Common - recombination factor protein RarA SSU05_2113 242 COG2256 MGS1, ATPase related to the helicase subunit of the Holliday junction resolvase DNA replication, recombination, and repair 146318957 Common - hypothetical protein SSU05_1303 146 COG0327 COG0327, Uncharacterized conserved protein Function unknown 146318256 Common - Transcriptional regulator SSU05_0602 60 COG1316 LytR, Transcriptional regulator Transcription 146318265 Common - Transposase SSU05_0611 32 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 146319491 Common - hypothetical protein SSU05_1837 3 None None None 146318716 Pathogen - hypothetical protein SSU05_1062 1 None None None 146318132 Common - Cell division septal protein SSU05_0478 12 COG1589 FtsQ, Cell division septal protein Cell envelope biogenesis, outer membrane 146318484 Common - ATPase component of ABC transporters with duplicated ATPase domains SSU05_0830 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 146318254 Common - putative prephenate dehydratase SSU05_0600 119 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 146318376 Common glpK glycerol kinase SSU05_0722 179 COG0554 GlpK, Glycerol kinase Energy production and conversion 146318330 Pathogen - Predicted integral membrane protein SSU05_0676 1 COG5523 COG5523, Predicted integral membrane protein Function unknown 146319043 Common - Threonine dehydrogenase and related Zn-dependent dehydrogenase SSU05_1388 205 COG1063 Tdh, Threonine dehydrogenase and related Zn-dependent dehydrogenases Amino acid transport and metabolism / General function prediction only 146318629 Common - protease, putative SSU05_0975 7 None None None 146319369 Common - Preprotein translocase subunit YidC SSU05_1715 177 COG0706 YidC, Preprotein translocase subunit YidC Intracellular trafficking and secretion 146317951 Common - hypothetical protein SSU05_0295 38 COG3830 COG3830, ACT domain-containing protein Signal transduction mechanisms 146318595 Common - DNA primase (type) SSU05_0941 8 None None None 146318705 Common - Predicted transcriptional regulator SSU05_1051 4 COG2932 COG2932, Predicted transcriptional regulator Transcription 146319427 Common - glutamine amidotransferase, class I SSU05_1773 120 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 146317720 Common ruvA Holliday junction DNA helicase motor protein SSU05_0060 209 COG0632 RuvA, Holliday junction resolvasome, DNA-binding subunit DNA replication, recombination, and repair 146317942 Common - ABC-type cobalt transport system, permease component CbiQ and related transporters SSU05_0286 21 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 146317750 Common - Preprotein translocase subunit SecY SSU05_0090 228 COG0201 SecY, Preprotein translocase subunit SecY Intracellular trafficking and secretion 146317915 Pathogen - hypothetical protein SSU05_0259 1 COG4586 COG4586, ABC-type uncharacterized transport system, ATPase component General function prediction only 146319032 Common - DNA polymerase I SSU05_1378 216 COG0749 PolA, DNA polymerase I - 3'-5' exonuclease and polymerase domains DNA replication, recombination, and repair 146318615 Pathogen - hypothetical protein SSU05_0961 1 None None None 146318587 Common - hypothetical protein SSU05_0933 6 None None None 146318676 Common - hypothetical protein SSU05_1022 19 COG3583 COG3583, Uncharacterized protein conserved in bacteria Function unknown 146318553 Common - hypothetical protein SSU05_0899 4 None None None 146318582 Common - hypothetical protein SSU05_0928 15 COG4734 ArdA, Antirestriction protein General function prediction only 146319105 Common - type I restriction-modification system, S subunit SSU05_1451 86 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 146319394 Common - ABC-type uncharacterized transport system, ATPase component SSU05_1740 3 None None None 146318765 Common spxA transcriptional regulator Spx SSU05_1111 63 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 146319272 Common - Acetyltransferase, including N-acetylases of ribosomal proteins SSU05_1618 78 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 146319698 Common - hippurate hydrolase-like protein SSU05_2044 170 COG1473 AbgB, Metal-dependent amidase/aminoacylase/carboxypeptidase General function prediction only 146319578 Common cysS cysteinyl-tRNA synthetase SSU05_1924 241 COG0215 CysS, Cysteinyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146319693 Common - Transcriptional regulator SSU05_2039 8 COG1846 MarR, Transcriptional regulators Transcription 146318208 Pathogen - hypothetical protein SSU05_0554 1 None None None 146318875 Common - Phosphotransferase system, mannose/fructose-specific component IIA SSU05_1221 63 COG2893 ManX, Phosphotransferase system, mannose/fructose-specific component IIA Carbohydrate transport and metabolism 146319552 Common rplM 50S ribosomal protein L13 SSU05_1898 220 COG0102 RplM, Ribosomal protein L13 Translation, ribosomal structure and biogenesis 146318700 Common - hypothetical protein SSU05_1046 2 None None None 146318852 Common - hypothetical protein SSU05_1198 33 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 146318125 Common - Signal peptidase I SSU05_0471 72 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 146319478 Common - putative translation elongation factor EF-P SSU05_1824 23 COG0231 Efp, Translation elongation factor P (EF-P)/translation initiation factor 5A (eIF-5A) Translation, ribosomal structure and biogenesis 146318071 Common - hypothetical protein SSU05_0416 11 COG4474 COG4474, Uncharacterized protein conserved in bacteria Function unknown 146319347 Common - Predicted acyltransferase SSU05_1693 81 COG1835 COG1835, Predicted acyltransferases Lipid metabolism 146317983 Pathogen - hypothetical protein SSU05_0327 1 None None None 146319164 Common gyrB DNA gyrase subunit B SSU05_1510 230 COG0187 GyrB, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), B subunit DNA replication, recombination, and repair 146319152 Common - hypothetical protein SSU05_1498 2 None None None 146318292 Common - D-alanine--D-alanyl carrier protein ligase SSU05_0638 218 COG1020 EntF, Non-ribosomal peptide synthetase modules and related proteins Secondary metabolites biosynthesis, transport, and catabolism 146318744 Common - transposase of IS200 family SSU05_1090 73 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 146319465 Common - aspartate kinase SSU05_1811 235 COG0527 LysC, Aspartokinases Amino acid transport and metabolism 146318394 Common - cobalt ABC transporter permease protein SSU05_0740 60 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 146319190 Common - chorismate mutase SSU05_1536 24 COG1605 PheA, Chorismate mutase Amino acid transport and metabolism 146317765 Pathogen - hypothetical protein SSU05_0107 1 None None None 146318088 Common - Predicted hydrolase of the HAD superfamily SSU05_0433 223 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 146317934 Common hisS histidyl-tRNA synthetase SSU05_0278 248 COG0124 HisS, Histidyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146318942 Common - polysaccharide biosynthesis protein/putative rhamnosyl transferase SSU05_1288 134 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146317851 Common - Predicted phosphosugar isomerase SSU05_0195 39 COG2222 AgaS, Predicted phosphosugar isomerases Cell envelope biogenesis, outer membrane 146318062 Pathogen - hypothetical protein SSU05_0407 1 None None None 146318389 Common - thiamine-phosphate pyrophosphorylase SSU05_0735 206 COG0352 ThiE, Thiamine monophosphate synthase Coenzyme metabolism 146317844 Common - hypothetical protein SSU05_0186 2 None None None 146319325 Common - Type II secretory pathway, prepilin signal peptidase PulO and related peptidases SSU05_1671 121 COG1989 PulO, Type II secretory pathway, prepilin signal peptidase PulO and related peptidases Cell motility and secretion / Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 146318924 Common infC translation initiation factor IF-3 SSU05_1270 212 COG0290 InfC, Translation initiation factor 3 (IF-3) Translation, ribosomal structure and biogenesis 146319382 Common - primosomal protein DnaI SSU05_1728 36 COG1484 DnaC, DNA replication protein DNA replication, recombination, and repair 146318531 Common - hypothetical protein SSU05_0877 5 None None None 146319781 Common - Surface antigen SSU05_2127 8 COG3942 COG3942, Surface antigen General function prediction only 146317729 Common - hypothetical protein SSU05_0069 26 COG3575 COG3575, Uncharacterized protein conserved in bacteria Function unknown 146318646 Common - Uncharacterized NAD(FAD)-dependent dehydrogenase SSU05_0992 245 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 146317963 Common - Predicted transcriptional regulator SSU05_0307 51 COG3655 COG3655, Predicted transcriptional regulator Transcription 146318105 Common - Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC SSU05_0451 36 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 146319582 Common - hypothetical protein SSU05_1928 26 COG3981 COG3981, Predicted acetyltransferase General function prediction only 146319033 Common - hypothetical protein SSU05_1379 1 None None None 146318754 Common - Phosphate uptake regulator SSU05_1100 61 COG0704 PhoU, Phosphate uptake regulator Inorganic ion transport and metabolism 146319291 Common - transposase of IS200 family SSU05_1637 70 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 146317694 Common - Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase SSU05_0034 233 COG0041 PurE, Phosphoribosylcarboxyaminoimidazole (NCAIR) mutase Nucleotide transport and metabolism 146318114 Pathogen - hypothetical protein SSU05_0460 1 None None None 146318894 Pathogen - hypothetical protein SSU05_1240 1 None None None 146318508 Common - Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) SSU05_0854 8 COG0741 MltE, Soluble lytic murein transglycosylase and related regulatory proteins (some contain LysM/invasin domains) Cell envelope biogenesis, outer membrane 146319684 Common - Response regulator of the LytR/AlgR family SSU05_2030 11 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 146318069 Common - Membrane carboxypeptidase (penicillin-binding protein) SSU05_0414 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 146319484 Common - Mg2+ and Co2+ transporter SSU05_1830 66 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 146317907 Pathogen - Predicted ATPase involved in replication control, Cdc46/Mcm family SSU05_0251 1 None None None 146319788 Common - ABC-type sugar transport system, permease component SSU05_2134 149 COG1175 UgpA, ABC-type sugar transport systems, permease components Carbohydrate transport and metabolism 146317854 Common - Methyl-accepting chemotaxis protein SSU05_0198 2 None None None 146317865 Pathogen - hypothetical protein SSU05_0209 1 None None None 146318327 Pathogen - hypothetical protein SSU05_0674 1 None None None 146318000 Common - L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D SSU05_0345 126 COG0252 AnsB, L-asparaginase/archaeal Glu-tRNAGln amidotransferase subunit D Amino acid transport and metabolism / Translation, ribosomal structure and biogenesis 146318945 Common - Glycosyltransferase SSU05_1291 4 None None None 146319172 Common - hypothetical protein SSU05_1518 2 None None None 146318054 Pathogen - hypothetical protein SSU05_0399 1 None None None 146317929 Pathogen - Methyl-accepting chemotaxis protein SSU05_0273 1 None None None 146318985 Common rplA 50S ribosomal protein L1 SSU05_1331 242 COG0081 RplA, Ribosomal protein L1 Translation, ribosomal structure and biogenesis 146319559 Common - hypothetical protein SSU05_1905 9 COG4129 COG4129, Predicted membrane protein Function unknown 146319377 Pathogen - hypothetical protein SSU05_1723 1 None None None 146318177 Common - Predicted membrane protein SSU05_0523 13 COG3859 COG3859, Predicted membrane protein Function unknown 146318936 Common - Predicted membrane protein SSU05_1282 2 COG4713 COG4713, Predicted membrane protein Function unknown 146318989 Common - DNA segregation ATPase FtsK/SpoIIIE and related proteins SSU05_1335 199 COG1674 FtsK, DNA segregation ATPase FtsK/SpoIIIE and related proteins Cell division and chromosome partitioning 146318966 Common - Short-chain dehydrogenase of various substrate specificities SSU05_1312 235 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146319433 Common - mannose-specific PTS IIC SSU05_1779 34 COG3715 ManY, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIC Carbohydrate transport and metabolism 146319097 Common - Maltodextrin phosphorylase SSU05_1443 90 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 146318028 Common - Amidases related to nicotinamidase SSU05_0373 74 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 146319087 Common - 30S Ribosomal protein S21 SSU05_1433 121 COG0828 RpsU, Ribosomal protein S21 Translation, ribosomal structure and biogenesis 146318709 Pathogen - ABC-type multidrug transport system, ATPase and permease component SSU05_1055 1 None None None 146318338 Common - type III restriction-modification system, restriction endonuclease subunit SSU05_0684 43 COG3587 COG3587, Restriction endonuclease Defense mechanisms 146318822 Common - hypothetical protein SSU05_1168 4 None None None 146318668 Common - ADP-glucose pyrophosphorylase SSU05_1014 116 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 146319374 Common murC UDP-N-acetylmuramate--L-alanine ligase SSU05_1720 211 COG0773 MurC, UDP-N-acetylmuramate-alanine ligase Cell envelope biogenesis, outer membrane 146319176 Pathogen - hypothetical protein SSU05_1522 1 None None None 146318653 Common - Nucleotide-binding protein implicated in inhibition of septum formation SSU05_0999 176 COG0424 Maf, Nucleotide-binding protein implicated in inhibition of septum formation Cell division and chromosome partitioning 146318167 Common - Membrane-fusion protein SSU05_0513 64 COG0845 AcrA, Membrane-fusion protein Cell envelope biogenesis, outer membrane 146317870 Common - ABC-type xylose transport system, periplasmic component SSU05_0214 13 None None None 146318623 Common - Type IV secretory pathway, VirB4 component SSU05_0969 38 COG3451 VirB4, Type IV secretory pathway, VirB4 components Intracellular trafficking and secretion 146318382 Common - Oligoendopeptidase F SSU05_0728 86 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 146317877 Common - Cation transport ATPase SSU05_0221 212 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 146317781 Common - hypothetical protein SSU05_0123 5 COG4699 COG4699, Uncharacterized protein conserved in bacteria Function unknown 146317979 Common - hypothetical protein SSU05_0323 60 COG1959 COG1959, Predicted transcriptional regulator Transcription 146318101 Common - Transcriptional regulator SSU05_0447 125 COG2188 PhnF, Transcriptional regulators Transcription 146318152 Pathogen - hypothetical protein SSU05_0498 1 None None None 146318736 Pathogen - hypothetical protein SSU05_1082 1 None None None 146319676 Pathogen - hypothetical protein SSU05_2023 1 None None None 146317777 Common - Tyrosyl-tRNA synthetase SSU05_0119 217 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146319199 Common - ABC-type branched-chain amino acid transport system, ATPase component SSU05_1545 49 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 146318970 Common miaA tRNA delta(2)-isopentenylpyrophosphate transferase SSU05_1316 214 COG0324 MiaA, tRNA delta(2)-isopentenylpyrophosphate transferase Translation, ribosomal structure and biogenesis 146317736 Common rplV 50S ribosomal protein L22 SSU05_0076 229 COG0091 RplV, Ribosomal protein L22 Translation, ribosomal structure and biogenesis 146318081 Common - tRNA and rRNA cytosine-C5-methylase SSU05_0426 208 COG0144 Sun, tRNA and rRNA cytosine-C5-methylases Translation, ribosomal structure and biogenesis 146319002 Common - Cation transport ATPase SSU05_1348 232 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 146319064 Common - Cell division protein SSU05_1410 69 COG2177 FtsX, Cell division protein Cell division and chromosome partitioning 146319075 Common - hypothetical protein SSU05_1421 33 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 146318274 Common - hypothetical protein SSU05_0620 140 COG1660 COG1660, Predicted P-loop-containing kinase General function prediction only 146318191 Common - hypothetical protein SSU05_0537 3 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 146319268 Common - hypothetical protein SSU05_1614 18 COG4708 COG4708, Predicted membrane protein Function unknown 146317835 Common - extracellular protein SSU05_0177 2 None None None 146319015 Common - ABC-type polar amino acid transport system, ATPase component SSU05_1361 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 146318998 Common - Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family SSU05_1344 201 COG0652 PpiB, Peptidyl-prolyl cis-trans isomerase (rotamase) - cyclophilin family Posttranslational modification, protein turnover, chaperones 146318886 Common - transcriptional regulator, Cro/CI family SSU05_1232 48 COG1476 COG1476, Predicted transcriptional regulators Transcription 146319679 Common - amino acid permease SSU05_2025 104 COG0833 LysP, Amino acid transporters Amino acid transport and metabolism 146319085 Common - UDP-glucose 4-epimerase SSU05_1431 152 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 146318910 Common - hypothetical protein SSU05_1256 58 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 146319707 Common - Cytosine/adenosine deaminase SSU05_2053 214 COG0590 CumB, Cytosine/adenosine deaminases Nucleotide transport and metabolism / Translation, ribosomal structure and biogenesis 146317867 Common - Transcriptional regulator/sugar kinase SSU05_0211 18 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 146318964 Common - Phosphatidylserine/phosphatidylglycerophosphate/cardiolipi n synthases and related enzymes SSU05_1310 149 COG1502 Cls, Phosphatidylserine/phosphatidylglycerophosphate/cardioli pin synthases and related enzymes Lipid metabolism 146317686 Common - phosphoribosylaminoimidazole-succinocarboxamide synthase SSU05_0026 224 COG0152 PurC, Phosphoribosylaminoimidazolesuccinocarboxamide (SAICAR) synthase Nucleotide transport and metabolism 146319197 Common - ABC-type branched-chain amino acid transport system, ATPase component SSU05_1543 249 COG0410 LivF, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 146318391 Common - probable uridine phosphorylase SSU05_0737 93 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 146318846 Common - dsRNA-specific ribonuclease SSU05_1192 1 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 146319450 Common - acetyl-CoA carboxylase subunit alpha SSU05_1796 175 COG0825 AccA, Acetyl-CoA carboxylase alpha subunit Lipid metabolism 146318369 Common - fructose-6-phosphate aldolase SSU05_0715 105 COG0176 MipB, Transaldolase Carbohydrate transport and metabolism 146317994 Common - fructose-bisphosphate aldolase SSU05_0338 14 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 146319187 Common - hypothetical protein SSU05_1533 73 COG0618 COG0618, Exopolyphosphatase-related proteins General function prediction only 146319457 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase SSU05_1803 238 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146319634 Common - 30S ribosomal protein S2 SSU05_1980 247 COG0052 RpsB, Ribosomal protein S2 Translation, ribosomal structure and biogenesis 146318033 Common - Predicted nucleotidyltransferase SSU05_0378 27 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 146318345 Common - Predicted membrane protein SSU05_0691 5 COG2339 COG2339, Predicted membrane protein Function unknown 146319700 Common - 2,3,4,5-tetrahydropyridine-2-carboxylate N-succinyltransferase, putative SSU05_2047 20 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 146317747 Common rpsE 30S ribosomal protein S5 SSU05_0087 249 COG0098 RpsE, Ribosomal protein S5 Translation, ribosomal structure and biogenesis 146319226 Common - Predicted integral membrane protein SSU05_1572 7 COG5658 COG5658, Predicted integral membrane protein Function unknown 146318276 Common - hypothetical protein SSU05_0622 54 COG1481 COG1481, Uncharacterized protein conserved in bacteria Function unknown 146318780 Common - hypothetical protein SSU05_1126 5 None None None 146318712 Common - Pseudouridylate synthase, 23S RNA-specific SSU05_1058 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 146318835 Pathogen - hypothetical protein SSU05_1181 1 None None None 146319646 Common - Thiamine pyrophosphokinase SSU05_1992 35 COG1564 THI80, Thiamine pyrophosphokinase Coenzyme metabolism 146318226 Pathogen - Cps2I SSU05_0572 1 None None None 146319795 Common aspS aspartyl-tRNA synthetase SSU05_2141 249 COG0173 AspS, Aspartyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146318424 Pathogen - hypothetical protein SSU05_0771 1 None None None 146319302 Common - hypothetical protein SSU05_1648 11 COG4698 COG4698, Uncharacterized protein conserved in bacteria Function unknown 146318860 Common - NrdH-redoxin SSU05_1206 35 COG0695 GrxC, Glutaredoxin and related proteins Posttranslational modification, protein turnover, chaperones 146318098 Common recX recombination regulator RecX SSU05_0443 33 COG2137 OraA, Uncharacterized protein conserved in bacteria General function prediction only 146318829 Common - F0F1 ATP synthase subunit delta SSU05_1175 52 COG0712 AtpH, F0F1-type ATP synthase, delta subunit (mitochondrial oligomycin sensitivity protein) Energy production and conversion 146319111 Common - hypothetical protein SSU05_1457 120 COG1704 LemA, Uncharacterized conserved protein Function unknown 146319042 Common - tellurite resistance protein TehB SSU05_1389 48 COG3615 TehB, Uncharacterized protein/domain, possibly involved in tellurite resistance Inorganic ion transport and metabolism 146318763 Common - hypothetical protein SSU05_1109 185 COG0483 SuhB, Archaeal fructose-1,6-bisphosphatase and related enzymes of inositol monophosphatase family Carbohydrate transport and metabolism 146318869 Common - hyaluronidase SSU05_1215 10 None None None 146318565 Common - ABC transporter, NBP/MSD fusion protein SSU05_0911 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146318147 Common - hypothetical protein SSU05_0493 5 COG4703 COG4703, Uncharacterized protein conserved in bacteria Function unknown 146318141 Common - Cell division initiation protein SSU05_0487 39 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 146319327 Common nadE NAD synthetase SSU05_1673 133 COG0171 NadE, NAD synthase Coenzyme metabolism 146318362 Common - Transcriptional regulator, contains sigma factor-related N-terminal domain SSU05_0708 54 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 146319009 Common - ATPase component of ABC transporters with duplicated ATPase domains SSU05_1355 247 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 146319355 Common scpA segregation and condensation protein A SSU05_1701 139 COG1354 COG1354, Uncharacterized conserved protein Function unknown 146318466 Common - Subtilisin-like serine protease SSU05_0812 54 COG1538 TolC, Outer membrane protein Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146319560 Pathogen - hypothetical protein SSU05_1906 1 None None None 146318574 Common - Tn916, transcriptional regulator, putative SSU05_0920 5 COG1476 COG1476, Predicted transcriptional regulators Transcription 146318161 Pathogen - hypothetical protein SSU05_0507 1 None None None 146318787 Pathogen - Predicted membrane protein SSU05_1133 2 COG4709 COG4709, Predicted membrane protein Function unknown 162139881 Common pheS phenylalanyl-tRNA synthetase subunit alpha SSU05_1152 249 COG0016 PheS, Phenylalanyl-tRNA synthetase alpha subunit Translation, ribosomal structure and biogenesis 146319203 Common - hypothetical protein SSU05_1549 7 COG4471 COG4471, Uncharacterized protein conserved in bacteria Function unknown 146319839 Pathogen - hypothetical protein SSU05_2185 1 None None None 146319258 Common - Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain SSU05_1604 7 COG4768 COG4768, Uncharacterized protein containing a divergent version of the methyl-accepting chemotaxis-like domain General function prediction only 146318752 Common - Transposase and inactivated derivative SSU05_1098 35 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 146319051 Common era GTP-binding protein Era SSU05_1397 233 COG1159 Era, GTPase General function prediction only 146319522 Common - peptide ABC transporter, peptide-binding protein SSU05_1868 171 COG0747 DdpA, ABC-type dipeptide transport system, periplasmic component Amino acid transport and metabolism 146318569 Pathogen - hypothetical protein SSU05_0915 1 None None None 146318244 Pathogen - hypothetical protein SSU05_0590 1 None None None 146319546 Common - dihydroxy-acid dehydratase SSU05_1892 210 COG0129 IlvD, Dihydroxyacid dehydratase/phosphogluconate dehydratase Amino acid transport and metabolism / Carbohydrate transport and metabolism 146319024 Common - Glycosyltransferase SSU05_1370 92 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146319236 Common - hypothetical protein SSU05_1582 1 None None None 146319567 Common - Transposase and inactivated derivative SSU05_1913 93 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318814 Common - 2-keto-3-deoxy-6-phosphogluconate aldolase SSU05_1160 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 146318383 Common - Oxygen-sensitive ribonucleoside-triphosphate reductase SSU05_0729 45 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 146318319 Common - phosphoserine aminotransferase SSU05_0665 114 COG1932 SerC, Phosphoserine aminotransferase Coenzyme metabolism / Amino acid transport and metabolism 146319049 Common - Dephospho-CoA kinase SSU05_1395 206 COG0237 CoaE, Dephospho-CoA kinase Coenzyme metabolism 146319571 Common - glycosyl hydrolase-related protein SSU05_1917 17 None None None 146318238 Common - IS630-Spn1, transposase Orf2 SSU05_0584 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318219 Common - Cps2B SSU05_0565 23 COG3944 COG3944, Capsular polysaccharide biosynthesis protein Cell envelope biogenesis, outer membrane 146318830 Common - F0F1-type ATP synthase, subunit b SSU05_1176 163 COG0711 AtpF, F0F1-type ATP synthase, subunit b Energy production and conversion 146318214 Common - Transcriptional regulator SSU05_0560 2 COG1309 AcrR, Transcriptional regulator Transcription 146318456 Common - homoserine dehydrogenase SSU05_0801 217 COG0460 ThrA, Homoserine dehydrogenase Amino acid transport and metabolism 146318559 Common - transcriptional regulator, Cro/CI family SSU05_0905 13 COG1396 HipB, Predicted transcriptional regulators Transcription 146318973 Common - Cyanate permease SSU05_1319 71 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 146319241 Common fabG 3-ketoacyl-(acyl-carrier-protein) reductase SSU05_1587 235 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146318790 Common - Transcriptional regulator SSU05_1136 25 COG1846 MarR, Transcriptional regulators Transcription 146319816 Common - Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain SSU05_2162 20 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 146319170 Pathogen - hypothetical protein SSU05_1516 1 None None None 146319120 Common - SAM-dependent methyltransferase SSU05_1466 15 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146319537 Pathogen - hypothetical protein SSU05_1883 1 None None None 146319685 Common - hypothetical protein SSU05_2031 75 COG2013 COG2013, Uncharacterized conserved protein Function unknown 146317791 Common - Adenine-specific DNA methylase SSU05_0134 1 None None None 146318529 Common - hypothetical protein SSU05_0875 28 COG2739 COG2739, Uncharacterized protein conserved in bacteria Function unknown 146319103 Common - ribose-5-phosphate isomerase A SSU05_1449 165 COG0120 RpiA, Ribose 5-phosphate isomerase Carbohydrate transport and metabolism 146318459 Common - ABC-type spermidine/putrescine transport system, ATPase component SSU05_0805 249 COG3842 PotA, ABC-type spermidine/putrescine transport systems, ATPase components Amino acid transport and metabolism 146319280 Pathogen - ABC-type multidrug transport system, ATPase and permease component SSU05_1626 1 None None None 146317703 Pathogen - Predicted metal-dependent membrane protease SSU05_0042 2 COG4956 COG4956, Integral membrane protein (PIN domain superfamily) General function prediction only 146318554 Common - hypothetical protein SSU05_0900 61 COG3708 COG3708, Uncharacterized protein conserved in bacteria Function unknown 146319402 Pathogen - hypothetical protein SSU05_1748 1 None None None 146317716 Common - Folylpolyglutamate synthase SSU05_0056 216 COG0285 FolC, Folylpolyglutamate synthase Coenzyme metabolism 146319412 Common - hypothetical protein SSU05_1758 22 COG4769 COG4769, Predicted membrane protein Function unknown 146319267 Common - oxidoreductase, aldo/keto reductase family SSU05_1613 193 COG0656 ARA1, Aldo/keto reductases, related to diketogulonate reductase General function prediction only 146318049 Common - Glucan phosphorylase SSU05_0394 147 COG0058 GlgP, Glucan phosphorylase Carbohydrate transport and metabolism 146318476 Common - Transcriptional regulator of sugar metabolism SSU05_0822 116 COG1349 GlpR, Transcriptional regulators of sugar metabolism Transcription / Carbohydrate transport and metabolism 146319333 Common - Predicted secreted protein containing a PDZ domain SSU05_1679 45 COG3480 SdrC, Predicted secreted protein containing a PDZ domain Signal transduction mechanisms 146317894 Pathogen - hypothetical protein SSU05_0238 1 None None None 146318157 Common - putative mercuric resisitant regulatory protein SSU05_0503 121 COG0789 SoxR, Predicted transcriptional regulators Transcription 146319216 Common - cystathionine gamma-synthase SSU05_1562 206 COG0626 MetC, Cystathionine beta-lyases/cystathionine gamma-synthases Amino acid transport and metabolism 146319715 Common - Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) SSU05_2061 40 COG1762 PtsN, Phosphotransferase system mannitol/fructose-specific IIA domain (Ntr-type) Carbohydrate transport and metabolism / Signal transduction mechanisms 146319746 Pathogen - hypothetical protein SSU05_2092 1 None None None 146318859 Common - aconitate hydratase SSU05_1205 223 COG1048 AcnA, Aconitase A Energy production and conversion 146318697 Common - Ribose 5-phosphate isomerase RpiB SSU05_1043 121 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 146317884 Common - Predicted dehydrogenase and related proteins SSU05_0228 121 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 146317772 Pathogen - hypothetical protein SSU05_0114 1 None None None 146319770 Common - 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases SSU05_2116 133 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 146319721 Common - putative amino acid ABC transporter, ATP-binding protein SSU05_2067 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 146318850 Pathogen - Predicted transcriptional regulator SSU05_1196 1 None None None 146318463 Common - Chloride channel protein EriC SSU05_0809 138 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 146318604 Pathogen - hypothetical protein SSU05_0950 1 None None None 146318287 Pathogen - hypothetical protein SSU05_0633 1 None None None 146318542 Common - ABC-type antimicrobial peptide transport system, permease component SSU05_0888 11 None None None 146319594 Common - 16S rRNA uridine-516 pseudouridylate synthase and related Pseudouridylate synthase SSU05_1940 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 146318431 Common - thiamine biosynthesis protein ThiI SSU05_0777 94 COG0301 ThiI, Thiamine biosynthesis ATP pyrophosphatase Coenzyme metabolism 146318196 Common dnaE DNA polymerase III DnaE SSU05_0542 216 COG0587 DnaE, DNA polymerase III, alpha subunit DNA replication, recombination, and repair 146318310 Pathogen - CBS domain protein SSU05_0656 1 None None None 146319830 Common - ABC-type cobalt transport system, ATPase component SSU05_2176 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 146318410 Common - hypothetical protein SSU05_0756 170 COG0344 COG0344, Predicted membrane protein Function unknown 146319058 Common - hypothetical protein SSU05_1404 111 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 146318520 Pathogen - hypothetical protein SSU05_0866 1 None None None 146319670 Common - argininosuccinate lyase SSU05_2016 237 COG0165 ArgH, Argininosuccinate lyase Amino acid transport and metabolism 146319387 Common - 6-phosphogluconate dehydrogenase SSU05_1733 104 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 146319610 Common - Transcriptional regulator SSU05_1956 8 COG1309 AcrR, Transcriptional regulator Transcription 146318919 Common - Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily SSU05_1265 2 None None None 146319472 Common - Beta-fructosidases (levanase/invertase) SSU05_1818 50 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 146319641 Common - Pseudouridylate synthase, 23S RNA-specific SSU05_1987 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 146318301 Common - ABC-type Fe3+-siderophore transport system, permease component SSU05_0647 187 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 146318223 Common - Cps2F SSU05_0569 30 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146318688 Pathogen - hypothetical protein SSU05_1034 1 None None None 146319524 Common - D-alanyl-D-alanine carboxypeptidase SSU05_1870 153 COG1686 DacC, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 146318907 Common - ABC-type uncharacterized transport system, ATPase component SSU05_1253 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 146318661 Common - orotate phosphoribosyltransferase SSU05_1007 198 COG0461 PyrE, Orotate phosphoribosyltransferase Nucleotide transport and metabolism 146319320 Common - Oligoendopeptidase F SSU05_1666 49 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 146318654 Common - putative 5'-nucleotidase SSU05_1000 118 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 146319326 Common - nicotinate phosphoribosyltransferase SSU05_1672 123 COG1488 PncB, Nicotinic acid phosphoribosyltransferase Coenzyme metabolism 146318155 Common - hypothetical protein SSU05_0502 6 None None None 146319615 Common - prolyl-tRNA synthetase SSU05_1961 227 COG0442 ProS, Prolyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146318316 Common - DNA polymerase III subunit delta' SSU05_0662 202 COG0470 HolB, ATPase involved in DNA replication DNA replication, recombination, and repair 146318681 Common - ABC-type amino acid transport/signal transduction system, periplasmic component/domain SSU05_1027 181 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146318915 Common - prephenate dehydrogenase SSU05_1261 160 COG0287 TyrA, Prephenate dehydrogenase Amino acid transport and metabolism 146318809 Pathogen - Predicted phosphatase SSU05_1155 4 COG0546 Gph, Predicted phosphatases General function prediction only 146317701 Pathogen - Amino acid transporter SSU05_0041 2 None None None 146319774 Common - Transposase and inactivated derivative SSU05_2120 6 None None None 146318224 Common - Glycosyltransferase SSU05_0570 222 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146319308 Common - Geranylgeranyl pyrophosphate synthase SSU05_1654 243 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 146318273 Common - Putative translation initiation inhibitor, yjgF family SSU05_0619 187 COG0251 TdcF, Putative translation initiation inhibitor, yjgF family Translation, ribosomal structure and biogenesis 146319718 Common - Type II secretory pathway, pullulanase PulA and related glycosidases SSU05_2064 158 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 146318193 Common - Predicted membrane protein SSU05_0539 5 None None None 146318881 Common - Predicted metal-dependent membrane protease SSU05_1227 23 None None None 146319792 Common - Type II secretory pathway, pullulanase PulA and related glycosidases SSU05_2138 149 COG1523 PulA, Type II secretory pathway, pullulanase PulA and related glycosidases Carbohydrate transport and metabolism 146319117 Common - serine/threonine:Na+ symporter SSU05_1463 148 COG3633 SstT, Na+/serine symporter Amino acid transport and metabolism 146318549 Pathogen - hypothetical protein SSU05_0895 1 None None None 146318689 Common - Galactose mutarotase and related enzyme SSU05_1035 41 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 146318421 Common - Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase SSU05_0767 161 COG0115 IlvE, Branched-chain amino acid aminotransferase/4-amino-4-deoxychorismate lyase Amino acid transport and metabolism / Coenzyme metabolism 146318926 Common - hypothetical protein SSU05_1273 1 None None None 146317715 Common - Transposase and inactivated derivative SSU05_0055 7 None None None 146317878 Common - Cation transport ATPase SSU05_0222 232 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 146319540 Common - ketol-acid reductoisomerase SSU05_1886 210 COG0059 IlvC, Ketol-acid reductoisomerase Amino acid transport and metabolism / Coenzyme metabolism 146318204 Common - amino acid (glutamine) ABC transporter, permease protein SSU05_0550 173 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146319210 Common - ABC-type sugar transport system, permease component SSU05_1556 142 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 146319745 Pathogen - hypothetical protein SSU05_2091 1 None None None 146318479 Common - Phosphotransferase system, fructose-specific IIC component SSU05_0825 67 COG1299 FruA, Phosphotransferase system, fructose-specific IIC component Carbohydrate transport and metabolism 146319054 Common - Transcriptional regulator SSU05_1400 71 COG1737 RpiR, Transcriptional regulators Transcription 146317775 Common - Tyrosyl-tRNA synthetase SSU05_0117 44 COG0162 TyrS, Tyrosyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146318148 Common - ABC-type amino acid transport system, permease component SSU05_0494 170 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146318605 Common - DNA recombinase, putative SSU05_0951 10 None None None 146319022 Pathogen - hypothetical protein SSU05_1368 1 None None None 146317842 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase SSU05_0184 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 146318396 Common - cobalt ABC transporter ATP-binding protein SSU05_0742 249 COG1122 CbiO, ABC-type cobalt transport system, ATPase component Inorganic ion transport and metabolism 146319547 Common - hypothetical protein SSU05_1893 3 None None None 146318666 Common - Transcriptional regulator SSU05_1012 175 COG0583 LysR, Transcriptional regulator Transcription 146319380 Common engA GTP-binding protein EngA SSU05_1726 231 COG1160 COG1160, Predicted GTPases General function prediction only 146318448 Common - pyrrolidone-carboxylate peptidase SSU05_0794 57 COG2039 Pcp, Pyrrolidone-carboxylate peptidase (N-terminal pyroglutamyl peptidase) Posttranslational modification, protein turnover, chaperones 146319498 Pathogen - hypothetical protein SSU05_1844 1 COG3589 COG3589, Uncharacterized conserved protein Function unknown 146318268 Common asnC asparaginyl-tRNA synthetase SSU05_0614 249 COG0017 AsnS, Aspartyl/asparaginyl-tRNA synthetases Translation, ribosomal structure and biogenesis 146319710 Common - Transcriptional antiterminator SSU05_2056 25 COG3711 BglG, Transcriptional antiterminator Transcription 146319217 Pathogen - hypothetical protein SSU05_1563 1 None None None 146319811 Common - hypothetical protein SSU05_2157 14 COG4466 Veg, Uncharacterized protein conserved in bacteria Function unknown 146317849 Common - Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase SSU05_0193 75 COG4781 COG4781, Membrane domain of membrane-anchored glycerophosphoryl diester phosphodiesterase Energy production and conversion 146319224 Common - Acyl carrier protein phosphodiesterase SSU05_1570 12 COG1182 AcpD, Acyl carrier protein phosphodiesterase Lipid metabolism 146319570 Common - ABC transporter, permease protein SSU05_1916 153 COG4209 LplB, ABC-type polysaccharide transport system, permease component Carbohydrate transport and metabolism 146319231 Common - putative internalin A precursor SSU05_1577 41 COG4886 COG4886, Leucine-rich repeat (LRR) protein Function unknown 146319264 Pathogen - hypothetical protein SSU05_1610 1 None None None 146319534 Common - hypothetical protein SSU05_1880 94 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146319140 Common - ABC-type uncharacterized transport system, permease component SSU05_1486 71 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 146317989 Pathogen - hypothetical protein SSU05_0333 1 None None None 146318799 Common - NTP pyrophosphohydrolase including oxidative damage repair enzymes SSU05_1145 36 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146318524 Pathogen - hypothetical protein SSU05_0870 1 None None None 146318452 Common - putative ABC transporter, ATP-binding protein SSU05_0798 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146319029 Common - Predicted integral membrane protein SSU05_1375 9 COG5523 COG5523, Predicted integral membrane protein Function unknown 146318556 Common - Predicted hydrolase (HAD superfamily) SSU05_0902 9 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 146318306 Common - 1-acyl-sn-glycerol-3-phosphate acyltransferase SSU05_0652 73 COG0204 PlsC, 1-acyl-sn-glycerol-3-phosphate acyltransferase Lipid metabolism 146318034 Common - Predicted nucleotidyltransferase SSU05_0379 18 COG1323 COG1323, Predicted nucleotidyltransferase General function prediction only 146319565 Common - sensor histidine kinase, putative SSU05_1911 99 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 146319843 Common - Predicted membrane protein SSU05_2188 11 COG4485 COG4485, Predicted membrane protein Function unknown 146318143 Common ileS isoleucyl-tRNA synthetase SSU05_0489 249 COG0060 IleS, Isoleucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146319357 Common - CBS domain protein SSU05_1703 10 COG4109 COG4109, Predicted transcriptional regulator containing CBS domains Transcription 146319321 Common - pyruvate-formate lyase activating enzyme SSU05_1667 93 COG1180 PflA, Pyruvate-formate lyase-activating enzyme Posttranslational modification, protein turnover, chaperones 146318722 Common - hypothetical protein SSU05_1068 1 None None None 146318044 Common - ATPases with chaperone activity, ATP-binding subunit SSU05_0389 220 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 146318718 Pathogen - hypothetical protein SSU05_1064 1 COG4116 COG4116, Uncharacterized protein conserved in bacteria Function unknown 146318726 Common - DNA repair protein SSU05_1072 1 COG2003 RadC, DNA repair proteins DNA replication, recombination, and repair 146318777 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_1123 5 None None None 162139882 Common rpsS 30S ribosomal protein S19 SSU05_0075 243 COG0185 RpsS, Ribosomal protein S19 Translation, ribosomal structure and biogenesis 146318589 Common - hypothetical protein SSU05_0935 67 COG3593 COG3593, Predicted ATP-dependent endonuclease of the OLD family DNA replication, recombination, and repair 146319639 Common - penicillin-binding protein 2A SSU05_1985 204 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 146317992 Common - Fructose/tagatose bisphosphate aldolase SSU05_0336 141 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 146318820 Common - hypothetical protein SSU05_1166 3 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 146319286 Common - Predicted dehydrogenase and related proteins SSU05_1632 136 COG0673 MviM, Predicted dehydrogenases and related proteins General function prediction only 146318006 Common - Amidases related to nicotinamidase SSU05_0351 64 COG1335 PncA, Amidases related to nicotinamidase Secondary metabolites biosynthesis, transport, and catabolism 146319529 Common - ABC-type transport system involved in Fe-S cluster assembly, permease component SSU05_1875 178 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 146318827 Common - F0F1 ATP synthase subunit gamma SSU05_1173 208 COG0224 AtpG, F0F1-type ATP synthase, gamma subunit Energy production and conversion 146318888 Pathogen - hypothetical protein SSU05_1234 1 None None None 146319838 Common - tryptophanyl-tRNA synthetase II SSU05_2184 248 COG0180 TrpS, Tryptophanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146318801 Common - SPX domain-containing protein involved in vacuolar polyphosphate accumulation SSU05_1147 12 COG5036 COG5036, SPX domain-containing protein involved in vacuolar polyphosphate accumulation Inorganic ion transport and metabolism 146317783 Common - hypothetical protein SSU05_0125 62 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 146318996 Pathogen - hypothetical protein SSU05_1342 1 None None None 146319580 Common - Serine acetyltransferase SSU05_1926 188 COG1045 CysE, Serine acetyltransferase Amino acid transport and metabolism 146317831 Pathogen - hypothetical protein SSU05_0173 1 None None None 146318496 Common - 4-oxalocrotonate tautomerase SSU05_0842 16 COG1942 COG1942, Uncharacterized protein, 4-oxalocrotonate tautomerase homolog General function prediction only 146317930 Common - Methyl-accepting chemotaxis protein SSU05_0274 3 COG5373 COG5373, Predicted membrane protein Function unknown 146318073 Common - Predicted N6-adenine-specific DNA methylase SSU05_0418 132 COG0116 COG0116, Predicted N6-adenine-specific DNA methylase DNA replication, recombination, and repair 146319255 Common - ABC-type proline/glycine betaine transport system, ATPase component SSU05_1601 249 COG1125 OpuBA, ABC-type proline/glycine betaine transport systems, ATPase components Amino acid transport and metabolism 146318091 Common - hypothetical protein SSU05_0436 133 COG1739 COG1739, Uncharacterized conserved protein Function unknown 146319686 Common - hypothetical protein SSU05_2032 54 COG0288 CynT, Carbonic anhydrase Inorganic ion transport and metabolism 146318427 Common - putative ribosomal protein S1-like DNA-binding protein SSU05_0773 1 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 146318472 Common - Na+-driven multidrug efflux pump SSU05_0818 87 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 146318402 Common - ABC-type multidrug transport system, ATPase component SSU05_0748 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146319802 Common - Response regulator of the LytR/AlgR family SSU05_2148 113 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 146318416 Common - hypothetical protein SSU05_0762 17 COG3339 COG3339, Uncharacterized conserved protein Function unknown 146317788 Common - Type II secretory pathway, pseudopilin PulG SSU05_0130 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 146319554 Common - hypothetical protein SSU05_1900 10 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 146318519 Pathogen - hypothetical protein SSU05_0865 1 None None None 146318614 Common - SalB SSU05_0960 15 COG4403 LcnDR2, Lantibiotic modifying enzyme Defense mechanisms 146318782 Common - peptidase T SSU05_1128 55 COG2195 PepD, Di- and tripeptidases Amino acid transport and metabolism 146318368 Common - Pyruvate-formate lyase SSU05_0714 59 COG1882 PflD, Pyruvate-formate lyase Energy production and conversion 146317924 Common - Formate/nitrite family of transporters SSU05_0269 60 COG2116 FocA, Formate/nitrite family of transporters Inorganic ion transport and metabolism 146319422 Common - ABC-type metal ion transport system, permease component SSU05_1768 100 COG2011 AbcD, ABC-type metal ion transport system, permease component Inorganic ion transport and metabolism 146318538 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain SSU05_0884 207 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146317838 Common - hypothetical protein SSU05_0180 3 None None None 146318733 Common - Uncharacterized ABC-type transport system, permease component SSU05_1079 109 COG1079 COG1079, Uncharacterized ABC-type transport system, permease component General function prediction only 146319703 Common - hypothetical protein SSU05_2049 3 None None None 146318296 Common - putative low temperature requirement A protein SSU05_0642 10 COG4292 COG4292, Predicted membrane protein Function unknown 146319339 Common - Response regulator SSU05_1685 216 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146318505 Common - hypothetical protein SSU05_0851 13 COG0456 RimI, Acetyltransferases General function prediction only 146319005 Common - hypothetical protein SSU05_1351 1 None None None 146317968 Common - phosphomethylpyrimidine kinase SSU05_0312 218 COG0351 ThiD, Hydroxymethylpyrimidine/phosphomethylpyrimidine kinase Coenzyme metabolism 146319090 Common - Predicted sugar phosphatases of the HAD superfamily SSU05_1436 95 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 146317689 Common - phosphoribosylaminoimidazole synthetase SSU05_0029 234 COG0150 PurM, Phosphoribosylaminoimidazole (AIR) synthetase Nucleotide transport and metabolism 146317953 Common - putative phosphoglycerate mutase SSU05_0297 58 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 146317825 Common - probable transcriptional regulator SSU05_0167 143 COG2207 AraC, AraC-type DNA-binding domain-containing proteins Transcription 146318963 Common - Single-stranded DNA-specific exonuclease SSU05_1309 195 COG0608 RecJ, Single-stranded DNA-specific exonuclease DNA replication, recombination, and repair 146317706 Pathogen - ABC-type sugar transport system, permease component SSU05_0046 2 None None None 146319179 Pathogen - hypothetical protein SSU05_1525 1 None None None 146317978 Common - NADH:flavin oxidoreductase, Old Yellow Enzyme family SSU05_0322 180 COG1902 NemA, NADH:flavin oxidoreductases, Old Yellow Enzyme family Energy production and conversion 146317892 Common - acetyltransferase, GNAT family family SSU05_0236 19 COG1246 ArgA, N-acetylglutamate synthase and related acetyltransferases Amino acid transport and metabolism 146319104 Common - Type I restriction enzyme EcoKI specificity protein (S protein) SSU05_1450 74 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 146318841 Common - Signal recognition particle GTPase SSU05_1187 247 COG0552 FtsY, Signal recognition particle GTPase Intracellular trafficking and secretion 146319295 Common - 3-hydroxy-3-methylglutaryl CoA synthase SSU05_1641 65 COG3425 PksG, 3-hydroxy-3-methylglutaryl CoA synthase Lipid metabolism 146318635 Common - hypothetical protein SSU05_0981 7 None None None 146318084 Common - Predicted membrane protein SSU05_0429 9 COG4758 COG4758, Predicted membrane protein Function unknown 146318947 Common - Muramidase (flagellum-specific) SSU05_1293 69 COG1705 FlgJ, Muramidase (flagellum-specific) Cell motility and secretion / Intracellular trafficking and secretion 146318198 Common - pyruvate kinase SSU05_0544 220 COG0469 PykF, Pyruvate kinase Carbohydrate transport and metabolism 146317980 Common - Transcriptional regulator SSU05_0324 21 COG1309 AcrR, Transcriptional regulator Transcription 146319655 Common ksgA dimethyladenosine transferase SSU05_2001 248 COG0030 KsgA, Dimethyladenosine transferase (rRNA methylation) Translation, ribosomal structure and biogenesis 146318089 Common - hypothetical protein SSU05_0434 233 COG1098 VacB, Predicted RNA binding protein (contains ribosomal protein S1 domain) Translation, ribosomal structure and biogenesis 146318616 Common - SNF2 family protein SSU05_0962 84 COG4646 COG4646, DNA methylase Transcription / DNA replication, recombination, and repair 146318318 Common - Predicted methyltransferase SSU05_0664 210 COG0313 COG0313, Predicted methyltransferases General function prediction only 146317860 Common - Putative NADH-flavin reductase SSU05_0204 55 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 146318703 Pathogen - hypothetical protein SSU05_1049 2 None None None 146318756 Common - ABC-type phosphate transport system, ATPase component SSU05_1102 249 COG1117 PstB, ABC-type phosphate transport system, ATPase component Inorganic ion transport and metabolism 146317935 Common - alcohol dehydrogenase SSU05_0279 216 COG1064 AdhP, Zn-dependent alcohol dehydrogenases General function prediction only 146318123 Common - hypothetical protein SSU05_0469 1 None None None 146317966 Common - Fe2+/Zn2+ uptake regulation protein SSU05_0310 205 COG0735 Fur, Fe2+/Zn2+ uptake regulation proteins Inorganic ion transport and metabolism 146319772 Common - anaerobic ribonucleoside triphosphate reductase SSU05_2118 98 COG1328 NrdD, Oxygen-sensitive ribonucleoside-triphosphate reductase Nucleotide transport and metabolism 146317872 Common - putative ABC-transport protein, membrane component SSU05_0216 193 COG0600 TauC, ABC-type nitrate/sulfonate/bicarbonate transport system, permease component Inorganic ion transport and metabolism 146318580 Common - hypothetical protein SSU05_0926 17 COG0433 COG0433, Predicted ATPase General function prediction only 146318335 Pathogen - hypothetical protein SSU05_0681 1 None None None 146318308 Common - Predicted membrane metal-binding protein SSU05_0654 130 COG2333 ComEC, Predicted hydrolase (metallo-beta-lactamase superfamily) General function prediction only 146319520 Common - ABC-type oligopeptide transport system, ATPase component SSU05_1866 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 146318025 Common - Predicted HD superfamily hydrolase involved in NAD metabolism SSU05_0370 43 COG1713 COG1713, Predicted HD superfamily hydrolase involved in NAD metabolism Coenzyme metabolism 146318921 Pathogen - Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit SSU05_1267 1 None None None 146319506 Common - hypothetical protein SSU05_1852 9 COG0510 CotS, Predicted choline kinase involved in LPS biosynthesis Cell envelope biogenesis, outer membrane 146319672 Pathogen - hypothetical protein SSU05_2018 1 None None None 146317665 Common - Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase SSU05_0003 60 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 146319481 Pathogen - hypothetical protein SSU05_1827 1 None None None 146317901 Common - hypothetical protein SSU05_0245 3 COG4652 COG4652, Uncharacterized protein conserved in bacteria Function unknown 146318163 Common - hypothetical protein SSU05_0509 103 COG1268 BioY, Uncharacterized conserved protein General function prediction only 146318961 Common - adenine phosphoribosyltransferase SSU05_1307 180 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 146319385 Common - probable permease SSU05_1731 191 COG0628 PerM, Predicted permease General function prediction only 146318917 Common aroD 3-dehydroquinate dehydratase SSU05_1263 50 COG0710 AroD, 3-dehydroquinate dehydratase Amino acid transport and metabolism 146317725 Common spxA transcriptional regulator Spx SSU05_0065 56 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 146319536 Common - Amino acid transport ATP-binding protein SSU05_1882 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 146319728 Common - Phosphotransferase system cellobiose-specific component IIA SSU05_2074 16 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 146318017 Common - Permease of the drug/metabolite transporter (DMT) superfamily SSU05_0362 114 COG2962 RarD, Predicted permeases General function prediction only 146318064 Common - ABC-type cobalt transport system, ATPase component SSU05_0409 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 146317812 Common - Predicted metalloendopeptidase SSU05_0153 63 COG3590 PepO, Predicted metalloendopeptidase Posttranslational modification, protein turnover, chaperones 146317819 Common - Predicted hydrolase of the metallo-beta-lactamase superfamily SSU05_0161 158 COG0595 COG0595, Predicted hydrolase of the metallo-beta-lactamase superfamily General function prediction only 146319430 Common - Permease SSU05_1776 134 COG2252 COG2252, Permeases General function prediction only 146319047 Common - Permease of the major facilitator superfamily SSU05_1393 87 COG2814 AraJ, Arabinose efflux permease Carbohydrate transport and metabolism 146319080 Pathogen - hypothetical protein SSU05_1426 1 None None None 146318694 Common - tagatose 1,6-diphosphate aldolase SSU05_1040 25 COG3684 LacD, Tagatose-1,6-bisphosphate aldolase Carbohydrate transport and metabolism 146319787 Common - ABC transporter substrate-binding protein - maltose/maltodextrin SSU05_2133 73 COG2182 MalE, Maltose-binding periplasmic proteins/domains Carbohydrate transport and metabolism 146318897 Common - Oligoendopeptidase F SSU05_1243 86 COG1164 COG1164, Oligoendopeptidase F Amino acid transport and metabolism 146318981 Common pyrH uridylate kinase SSU05_1327 235 COG0528 PyrH, Uridylate kinase Nucleotide transport and metabolism 146319343 Common - Dpr SSU05_1689 113 COG0783 Dps, DNA-binding ferritin-like protein (oxidative damage protectant) Inorganic ion transport and metabolism 146319234 Common - putative pyridoxal kinase SSU05_1580 28 COG2240 PdxK, Pyridoxal/pyridoxine/pyridoxamine kinase Coenzyme metabolism 146318503 Common - Methylase of polypeptide chain release factors SSU05_0849 234 COG2890 HemK, Methylase of polypeptide chain release factors Translation, ribosomal structure and biogenesis 146317820 Common - Uncharacterized conserved small protein SSU05_0162 10 COG5503 COG5503, Uncharacterized conserved small protein Function unknown 146318594 Pathogen - hypothetical protein SSU05_0940 1 None None None 146318817 Common - beta-D-glucuronidase SSU05_1163 70 COG3250 LacZ, Beta-galactosidase/beta-glucuronidase Carbohydrate transport and metabolism 146319271 Common - methionine aminopeptidase SSU05_1617 238 COG0024 Map, Methionine aminopeptidase Translation, ribosomal structure and biogenesis 146318156 Common - sortase-like protein SSU05_0501 22 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 146319464 Common - Predicted phosphatase/phosphohexomutase SSU05_1810 168 COG0637 COG0637, Predicted phosphatase/phosphohexomutase General function prediction only 146317785 Common - Type II secretory pathway, component PulF SSU05_0127 15 COG1459 PulF, Type II secretory pathway, component PulF Cell motility and secretion / Intracellular trafficking and secretion 146318461 Common - ABC-type spermidine/putrescine transport system, permease component II SSU05_0807 211 COG1177 PotC, ABC-type spermidine/putrescine transport system, permease component II Amino acid transport and metabolism 146317761 Pathogen - hypothetical protein SSU05_0103 1 None None None 146318512 Common - hypothetical protein SSU05_0858 1 None None None 146319589 Common - Xanthine/uracil permease SSU05_1935 122 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 146318294 Common - D-alanine--poly(phosphoribitol) ligase subunit 2 SSU05_0640 12 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146319439 Common - Type I restriction-modification system methyltransferase subunit SSU05_1785 142 COG0286 HsdM, Type I restriction-modification system methyltransferase subunit Defense mechanisms 146319784 Pathogen - hypothetical protein SSU05_2130 1 None None None 146318386 Common - predicted phosphatase/phosphohexomutase SSU05_0732 19 COG0546 Gph, Predicted phosphatases General function prediction only 146318116 Common - hypothetical protein SSU05_0462 4 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 146318527 Common guaA bifunctional GMP synthase/glutamine amidotransferase protein SSU05_0873 239 COG0519 GuaA, GMP synthase, PP-ATPase domain/subunit Nucleotide transport and metabolism 146319121 Common - hypothetical protein SSU05_1467 249 COG0488 Uup, ATPase components of ABC transporters with duplicated ATPase domains General function prediction only 146319161 Common - Transposase and inactivated derivative SSU05_1507 90 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 146319577 Common - hypothetical protein SSU05_1923 39 COG1939 COG1939, Uncharacterized protein conserved in bacteria Function unknown 146318714 Common - hypothetical protein SSU05_1060 102 COG2357 COG2357, Uncharacterized protein conserved in bacteria Function unknown 146317943 Common - ABC-type cobalt transport system, ATPase component SSU05_0287 249 COG1123 COG1123, ATPase components of various ABC-type transport systems, contain duplicated ATPase General function prediction only 146319441 Common - Type I site-specific restriction-modification system, R (restriction) subunit and related helicase SSU05_1787 138 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 146318934 Common - Glycosyltransferases involved in cell wall biogenesis SSU05_1280 214 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146319470 Common - Transcriptional regulator/sugar kinase SSU05_1816 26 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 146318240 Common - hypothetical protein SSU05_0586 2 None None None 146318537 Common - Signal transduction histidine kinase SSU05_0883 84 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146317806 Common - putative chaperonin GroEL SSU05_0148 247 COG0459 GroL, Chaperonin GroEL (HSP60 family) Posttranslational modification, protein turnover, chaperones 146318768 Common - Pseudouridine synthase SSU05_1114 245 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 146317912 Common - ABC-type uncharacterized transport system, permease component SSU05_0256 38 COG3694 COG3694, ABC-type uncharacterized transport system, permease component General function prediction only 146318691 Common - Phosphotransferase system cellobiose-specific component IIC SSU05_1037 38 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 146318053 Common - Phosphotransferase system IIC component, glucose/maltose/N-acetylglucosamine-specific SSU05_0398 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 146319753 Common - hypothetical protein SSU05_2099 7 COG4932 COG4932, Predicted outer membrane protein Cell envelope biogenesis, outer membrane 146319835 Common - hypothetical protein SSU05_2181 23 COG2501 COG2501, Uncharacterized conserved protein Function unknown 146318124 Pathogen - ATPase involved in DNA repair SSU05_0470 1 None None None 146319598 Common def peptide deformylase SSU05_1944 212 COG0242 Def, N-formylmethionyl-tRNA deformylase Translation, ribosomal structure and biogenesis 146319135 Pathogen - hypothetical protein SSU05_1481 1 None None None 146319229 Common - hypothetical protein SSU05_1575 60 COG1284 COG1284, Uncharacterized conserved protein Function unknown 146319118 Pathogen - hypothetical protein SSU05_1464 1 None None None 146318871 Common - Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID SSU05_1217 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 146317985 Common - hypothetical protein SSU05_0329 16 COG1215 COG1215, Glycosyltransferases, probably involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146319827 Common - LysM repeat protein SSU05_2173 12 COG3858 COG3858, Predicted glycosyl hydrolase General function prediction only 146318487 Pathogen - hypothetical protein SSU05_0833 1 None None None 146318878 Common - hypothetical protein SSU05_1224 25 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 146317794 Common - hypothetical protein SSU05_0136 5 None None None 146319510 Common - Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases SSU05_1856 238 COG0537 Hit, Diadenosine tetraphosphate (Ap4A) hydrolase and other HIT family hydrolases Nucleotide transport and metabolism / Carbohydrate transport and metabolism / General function prediction only 146319626 Common - Nicotinamide mononucleotide transporter SSU05_1972 44 COG3201 PnuC, Nicotinamide mononucleotide transporter Coenzyme metabolism 146319424 Common - Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases SSU05_1770 144 COG0624 ArgE, Acetylornithine deacetylase/Succinyl-diaminopimelate desuccinylase and related deacylases Amino acid transport and metabolism 146318464 Common - Transposase and inactivated derivative SSU05_0810 26 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318674 Common - NTP pyrophosphohydrolase including oxidative damage repair enzymes SSU05_1020 82 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146318862 Pathogen - hypothetical protein SSU05_1208 1 None None None 146318361 Common - Transcriptional regulator, contains sigma factor-related N-terminal domain SSU05_0707 12 COG2390 DeoR, Transcriptional regulator, contains sigma factor-related N-terminal domain Transcription 146319205 Common - putative ATP-dependent Clp protease, proteolytic subunit SSU05_1551 195 COG0740 ClpP, Protease subunit of ATP-dependent Clp proteases Posttranslational modification, protein turnover, chaperones / Intracellular trafficking and secretion 146318995 Common - Transcriptional regulator SSU05_1341 129 COG1609 PurR, Transcriptional regulators Transcription 146319107 Common - EcoA type I restriction-modification enzyme R subunit SSU05_1453 143 COG4096 HsdR, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 146318436 Common rpmA 50S ribosomal protein L27 SSU05_0782 215 COG0211 RpmA, Ribosomal protein L27 Translation, ribosomal structure and biogenesis 146318115 Pathogen - hypothetical protein SSU05_0461 1 None None None 146317708 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_0048 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146318480 Common - hypothetical protein SSU05_0826 4 COG4835 COG4835, Uncharacterized protein conserved in bacteria Function unknown 146318625 Common - ABC-type cobalt transport system, permease component CbiQ and related transporters SSU05_0971 3 COG3704 VirB6, Type IV secretory pathway, VirB6 components Intracellular trafficking and secretion 146317723 Common - recombination protein A SSU05_0063 1 None None None 146318377 Common - alpha-glycerophosphate oxidase SSU05_0723 148 COG0578 GlpA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 146319701 Pathogen - hypothetical protein SSU05_2045 1 None None None 146319607 Common - hypothetical protein SSU05_1953 45 COG1704 LemA, Uncharacterized conserved protein Function unknown 146319195 Pathogen - hypothetical protein SSU05_1541 1 None None None 146317676 Common - Hypoxanthine-guanine phosphoribosyltransferase SSU05_0014 153 COG0634 Hpt, Hypoxanthine-guanine phosphoribosyltransferase Nucleotide transport and metabolism 146318419 Common - Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain SSU05_0765 2 None None None 146319400 Pathogen - Hemolysins and related proteins containing CBS domains SSU05_1746 1 None None None 146319363 Common - cysteine aminopeptidase C SSU05_1709 17 COG3579 PepC, Aminopeptidase C Amino acid transport and metabolism 146319659 Common - NTP pyrophosphohydrolase including oxidative damage repair enzymes SSU05_2005 2 None None None 146318252 Common - 5-enolpyruvylshikimate-3-phosphate synthase SSU05_0598 210 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 146318955 Common - glucose-1-phosphate thymidylyltransferase SSU05_1301 234 COG1209 RfbA, dTDP-glucose pyrophosphorylase Cell envelope biogenesis, outer membrane 146319314 Common - two-component sensor SSU05_1660 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146318486 Common - Transcriptional regulator/sugar kinase SSU05_0832 164 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 146319156 Common - putative enolase SSU05_1503 246 COG0148 Eno, Enolase Carbohydrate transport and metabolism 146319040 Common - Cation transport ATPase SSU05_1386 175 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 146318645 Common - Rhodanese-related sulfurtransferase SSU05_0991 152 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146318174 Common - Fructose-2,6-bisphosphatase SSU05_0520 128 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 146319496 Common - hypothetical protein SSU05_1842 127 COG2860 COG2860, Predicted membrane protein Function unknown 146317753 Common rpsM 30S ribosomal protein S13 SSU05_0093 242 COG0099 RpsM, Ribosomal protein S13 Translation, ribosomal structure and biogenesis 146319397 Common - Protein required for the initiation of cell division SSU05_1743 4 COG4839 FtsL, Protein required for the initiation of cell division Cell division and chromosome partitioning 146318950 Common - dTDP-4-dehydrorhamnose reductase SSU05_1296 177 COG1091 RfbD, dTDP-4-dehydrorhamnose reductase Cell envelope biogenesis, outer membrane 146319066 Common - peptide chain release factor 2 SSU05_1412 216 COG1186 PrfB, Protein chain release factor B Translation, ribosomal structure and biogenesis 146319516 Common - hypothetical protein SSU05_1862 37 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 146318325 Common - Exonuclease III SSU05_0671 186 COG0708 XthA, Exonuclease III DNA replication, recombination, and repair 146318405 Common obgE GTPase ObgE SSU05_0751 249 COG0536 Obg, Predicted GTPase General function prediction only 146318547 Pathogen - hypothetical protein SSU05_0893 3 COG4200 COG4200, Uncharacterized protein conserved in bacteria Function unknown 146318856 Common - Isocitrate dehydrogenase SSU05_1202 222 COG0538 Icd, Isocitrate dehydrogenases Energy production and conversion 146319420 Common - Phage envelope protein SSU05_1766 8 COG5562 COG5562, Phage envelope protein General function prediction only 146319056 Common - N-acetylmannosamine-6-phosphate 2-epimerase SSU05_1402 43 COG3010 NanE, Putative N-acetylmannosamine-6-phosphate epimerase Carbohydrate transport and metabolism 146317748 Common rpmD 50S ribosomal protein L30 SSU05_0088 143 COG1841 RpmD, Ribosomal protein L30/L7E Translation, ribosomal structure and biogenesis 146319591 Common - hypothetical protein SSU05_1937 101 COG2233 UraA, Xanthine/uracil permeases Nucleotide transport and metabolism 146318836 Common - Predicted permease SSU05_1182 75 COG0701 COG0701, Predicted permeases General function prediction only 146319329 Common - Predicted Fe-S-cluster redox enzyme SSU05_1676 194 COG0820 COG0820, Predicted Fe-S-cluster redox enzyme General function prediction only 146319828 Common - ABC-type cobalt transport system, permease component CbiQ and related transporters SSU05_2174 88 COG0619 CbiQ, ABC-type cobalt transport system, permease component CbiQ and related transporters Inorganic ion transport and metabolism 146318358 Common - hypothetical protein SSU05_0704 8 None None None 146318607 Common - DNA recombinase, putative SSU05_0953 84 COG1961 PinR, Site-specific recombinases, DNA invertase Pin homologs DNA replication, recombination, and repair 146317848 Pathogen - hypothetical protein SSU05_0192 1 None None None 146319020 Common thrS threonyl-tRNA synthetase SSU05_1366 249 COG0441 ThrS, Threonyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146319549 Pathogen - hypothetical protein SSU05_1895 1 None None None 146319219 Pathogen - hypothetical protein SSU05_1565 1 None None None 146319460 Common acpP acyl carrier protein SSU05_1806 173 COG0236 AcpP, Acyl carrier protein Lipid metabolism / Secondary metabolites biosynthesis, transport, and catabolism 146319417 Common - hypothetical protein SSU05_1763 10 COG4224 COG4224, Uncharacterized protein conserved in bacteria Function unknown 146318450 Common - 30S ribosomal protein S16 SSU05_0796 213 COG0228 RpsP, Ribosomal protein S16 Translation, ribosomal structure and biogenesis 146319283 Common - hypothetical protein SSU05_1629 14 COG3326 COG3326, Predicted membrane protein Function unknown 146319563 Common - Regulator of polyketide synthase expression SSU05_1909 8 COG2508 COG2508, Regulator of polyketide synthase expression Signal transduction mechanisms / Secondary metabolites biosynthesis, transport, and catabolism 146318131 Common murG N-acetylglucosaminyl transferase SSU05_0477 206 COG0707 MurG, UDP-N-acetylglucosamine:LPS N-acetylglucosamine transferase Cell envelope biogenesis, outer membrane 146319238 Common - N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) SSU05_1584 238 COG1207 GlmU, N-acetylglucosamine-1-phosphate uridyltransferase (contains nucleotidyltransferase and I-patch acetyltransferase domains) Cell envelope biogenesis, outer membrane 146318642 Common - Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake SSU05_0988 2 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 146317882 Common - ribonuclease HIII SSU05_0226 29 COG1039 RnhC, Ribonuclease HIII DNA replication, recombination, and repair 146318797 Common - Dihydropteroate synthase and related enzymes SSU05_1143 218 COG0294 FolP, Dihydropteroate synthase and related enzymes Coenzyme metabolism 146319518 Common - peptide ABC transporter, permease protein SSU05_1864 220 COG1173 DppC, ABC-type dipeptide/oligopeptide/nickel transport systems, permease components Amino acid transport and metabolism / Inorganic ion transport and metabolism 146319532 Common - adaptor protein SSU05_1878 13 COG4862 MecA, Negative regulator of genetic competence, sporulation and motility Posttranslational modification, protein turnover, chaperones / Signal transduction mechanisms / Cell motility and secretion 146318522 Pathogen - hypothetical protein SSU05_0868 1 None None None 146318819 Pathogen - sugar transporter, putative SSU05_1165 1 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 146318036 Pathogen - hypothetical protein SSU05_0381 1 None None None 146319527 Common - NifU-like protein involved in Fe-S cluster formation SSU05_1873 160 COG0822 IscU, NifU homolog involved in Fe-S cluster formation Energy production and conversion 146318304 Common - ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component SSU05_0650 249 COG1120 FepC, ABC-type cobalamin/Fe3+-siderophores transport systems, ATPase components Inorganic ion transport and metabolism / Coenzyme metabolism 146318216 Common - hypothetical protein SSU05_0562 167 COG1167 ARO8, Transcriptional regulators containing a DNA-binding HTH domain and an aminotransferase domain (MocR family) and their eukaryotic orthologs Transcription / Amino acid transport and metabolism 146318058 Common - hypothetical protein SSU05_0403 73 COG1912 COG1912, Uncharacterized conserved protein Function unknown 146319622 Common - DNA nuclease SSU05_1968 46 COG2374 COG2374, Predicted extracellular nuclease General function prediction only 146318314 Common - hypothetical protein SSU05_0660 25 COG1284 COG1284, Uncharacterized conserved protein Function unknown 146319542 Common - Thiamine pyrophosphate-requiring enzyme SSU05_1888 221 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 146318282 Common - Predicted membrane protein SSU05_0628 38 COG1288 COG1288, Predicted membrane protein Function unknown 146317672 Common - Septum formation initiator SSU05_0010 12 COG2919 COG2919, Septum formation initiator Cell division and chromosome partitioning 146319073 Common - Cation transport ATPase SSU05_1419 197 COG0474 MgtA, Cation transport ATPase Inorganic ion transport and metabolism 146319122 Common - Phosphomannomutase SSU05_1468 242 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 146317889 Common - hypothetical protein SSU05_0233 2 None None None 146318172 Common - Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases SSU05_0518 82 COG2141 COG2141, Coenzyme F420-dependent N5,N10-methylene tetrahydromethanopterin reductase and related flavin-dependent oxidoreductases Energy production and conversion 146318932 Common - Glycosyltransferase SSU05_1278 78 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146319813 Common - Replicative DNA helicase SSU05_2159 207 COG0305 DnaB, Replicative DNA helicase DNA replication, recombination, and repair 146318250 Common - 5-enolpyruvylshikimate-3-phosphate synthase SSU05_0596 184 COG0128 AroA, 5-enolpyruvylshikimate-3-phosphate synthase Amino acid transport and metabolism 146317730 Common - ribosomal protein S10 SSU05_0070 247 COG0051 RpsJ, Ribosomal protein S10 Translation, ribosomal structure and biogenesis 146318280 Common - ornithine carbamoyltransferase SSU05_0626 240 COG0078 ArgF, Ornithine carbamoyltransferase Amino acid transport and metabolism 146317974 Common - Predicted transcriptional regulator SSU05_0318 51 COG1959 COG1959, Predicted transcriptional regulator Transcription 146318447 Common - SAM-dependent methyltransferase SSU05_0793 42 COG2521 COG2521, Predicted archaeal methyltransferase General function prediction only 146319776 Common - Response regulator of the LytR/AlgR family SSU05_2122 16 COG3279 LytT, Response regulator of the LytR/AlgR family Transcription / Signal transduction mechanisms 146318883 Common - hypothetical protein SSU05_1229 1 None None None 146318351 Pathogen - hypothetical protein SSU05_0697 1 None None None 146318434 Common - Branched-chain amino acid permease SSU05_0780 47 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 146317861 Pathogen - Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) SSU05_0205 1 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 146319743 Common - hypothetical protein SSU05_2089 14 COG1266 COG1266, Predicted metal-dependent membrane protease General function prediction only 146319800 Common - hypothetical protein SSU05_2146 2 None None None 146319207 Pathogen - hypothetical protein SSU05_1552 1 None None None 146318810 Common - D-mannonate oxidoreductase SSU05_1156 237 COG1028 FabG, Dehydrogenases with different specificities (related to short-chain alcohol dehydrogenases) Secondary metabolites biosynthesis, transport, and catabolism / General function prediction only 146318423 Common - putative ribosomal protein S1-like DNA-binding protein SSU05_0769 54 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 146319692 Common - putative ABC transporter (ATP-binding protein) SSU05_2038 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146317739 Common - 50S ribosomal protein L29 SSU05_0079 4 COG0255 RpmC, Ribosomal protein L29 Translation, ribosomal structure and biogenesis 146318532 Common - hypothetical protein SSU05_0878 2 None None None 146317713 Common - Predicted transcriptional regulator SSU05_0053 1 COG0033 Pgm, Phosphoglucomutase Carbohydrate transport and metabolism 146318803 Common - hypothetical protein SSU05_1149 12 COG3860 COG3860, Uncharacterized protein conserved in bacteria Function unknown 146318202 Common - Signal peptidase I SSU05_0548 46 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 146318683 Common - ABC-type polar amino acid transport system, ATPase component SSU05_1029 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 146318186 Common - hypothetical protein SSU05_0532 135 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 146318289 Pathogen - hypothetical protein SSU05_0635 1 None None None 146317711 Common - hypothetical protein SSU05_0051 5 COG3393 COG3393, Predicted acetyltransferase General function prediction only 146319798 Common - Glycosyltransferases involved in cell wall biogenesis SSU05_2144 166 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146318298 Common - 16S rRNA uridine-516 pseudouridylate synthase and related Pseudouridylate synthase SSU05_0644 204 COG1187 RsuA, 16S rRNA uridine-516 pseudouridylate synthase and related pseudouridylate synthases Translation, ribosomal structure and biogenesis 146319318 Pathogen - hypothetical protein SSU05_1664 2 None None None 146319739 Common - ATP-binding ABC transport protein SSU05_2085 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 146318136 Pathogen - hypothetical protein SSU05_0483 1 None None None 146318027 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_0372 8 COG1670 RimL, Acetyltransferases, including N-acetylases of ribosomal proteins Translation, ribosomal structure and biogenesis 146318784 Common - Predicted permease SSU05_1130 8 COG0679 COG0679, Predicted permeases General function prediction only 146318093 Common - Predicted amidophosphoribosyltransferase SSU05_0438 81 COG1040 ComFC, Predicted amidophosphoribosyltransferases General function prediction only 146318492 Common - Predicted GTPase SSU05_0838 20 COG0218 COG0218, Predicted GTPase General function prediction only 146319248 Common - ABC-type antimicrobial peptide transport system, ATPase component SSU05_1594 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 146318671 Common - ABC-type amino acid transport/signal transduction system, periplasmic component/domain SSU05_1017 185 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146319761 Common - Ribosomal protein L11 methylase SSU05_2107 26 COG2264 PrmA, Ribosomal protein L11 methylase Translation, ribosomal structure and biogenesis 146319790 Common - Predicted integral membrane protein SSU05_2136 3 COG5521 COG5521, Predicted integral membrane protein Function unknown 146317802 Common - hypothetical protein SSU05_0144 11 None None None 146317668 Common - translation-associated GTPase SSU05_0006 249 COG0012 COG0012, Predicted GTPase, probable translation factor Translation, ribosomal structure and biogenesis 146318439 Common - prolipoprotein signal peptidase; Lsp SSU05_0785 192 COG0597 LspA, Lipoprotein signal peptidase Cell envelope biogenesis, outer membrane / Intracellular trafficking and secretion 146318090 Common - O-acetylserine lyase SSU05_0435 220 COG0031 CysK, Cysteine synthase Amino acid transport and metabolism 146317946 Common - Mevalonate pyrophosphate decarboxylase SSU05_0290 31 COG3407 MVD1, Mevalonate pyrophosphate decarboxylase Lipid metabolism 146318414 Common - Protein involved in cell division SSU05_0760 10 COG2184 Fic, Protein involved in cell division Cell division and chromosome partitioning 146319166 Common - Rod shape determining protein SSU05_1512 207 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 146319649 Common - multidrug ABC transporter, ATP-binding protein SSU05_1995 249 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 146318246 Pathogen - hypothetical protein SSU05_0592 1 None None None 146318678 Common - Helicase subunit of the DNA excision repair complex SSU05_1024 232 COG0556 UvrB, Helicase subunit of the DNA excision repair complex DNA replication, recombination, and repair 146319407 Common - Membrane-associated lipoprotein involved in thiamine biosynthesis SSU05_1753 134 COG1477 ApbE, Membrane-associated lipoprotein involved in thiamine biosynthesis Coenzyme metabolism 146319705 Common pgi glucose-6-phosphate isomerase SSU05_2051 191 COG0166 Pgi, Glucose-6-phosphate isomerase Carbohydrate transport and metabolism 146319661 Pathogen - hypothetical protein SSU05_2007 2 COG3668 ParE, Plasmid stabilization system protein General function prediction only 146319556 Common - tRNA/rRNA methyltransferase SSU05_1902 215 COG0566 SpoU, rRNA methylases Translation, ribosomal structure and biogenesis 146318843 Common - Predicted hydrolase of the HAD superfamily SSU05_1189 108 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 146319572 Common - Transcriptional regulator/sugar kinase SSU05_1918 150 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 146319007 Common recR recombination protein RecR SSU05_1353 204 COG0353 RecR, Recombinational DNA repair protein (RecF pathway) DNA replication, recombination, and repair 146317827 Common - ABC-type sugar transport system, periplasmic component SSU05_0169 19 COG1653 UgpB, ABC-type sugar transport system, periplasmic component Carbohydrate transport and metabolism 146317920 Common - Predicted transcriptional regulator SSU05_0264 53 COG1695 COG1695, Predicted transcriptional regulators Transcription 146319666 Pathogen - hypothetical protein SSU05_2012 1 None None None 146318573 Common - hypothetical protein SSU05_0919 10 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 146318631 Pathogen - Arsenate reductase and related proteins, glutaredoxin family SSU05_0977 1 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 146318839 Common - hypothetical protein SSU05_1185 11 COG4912 COG4912, Predicted DNA alkylation repair enzyme DNA replication, recombination, and repair 146318611 Common - putative aminoglycoside 6-adenylyltansferase SSU05_0957 10 None None None 146318046 Common - ATPases with chaperone activity, ATP-binding subunit SSU05_0391 199 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 146319359 Common - putative deoxyribonucleotide triphosphate pyrophosphatase/unknown domain fusion protein SSU05_1705 237 COG0127 COG0127, Xanthosine triphosphate pyrophosphatase Nucleotide transport and metabolism 146318728 Common - sortase SSU05_1074 19 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 146317909 Common - dihydroorotate dehydrogenase 1A SSU05_0253 217 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 146318222 Common - Cps2E SSU05_0568 181 COG2148 WcaJ, Sugar transferases involved in lipopolysaccharide synthesis Cell envelope biogenesis, outer membrane 146317741 Common rplN 50S ribosomal protein L14 SSU05_0081 247 COG0093 RplN, Ribosomal protein L14 Translation, ribosomal structure and biogenesis 146317925 Common - hypothetical protein SSU05_0268 133 COG0580 GlpF, Glycerol uptake facilitator and related permeases (Major Intrinsic Protein Family) Carbohydrate transport and metabolism 146319018 Common - amino acid (glutamine) ABC transporter permease protein SSU05_1364 164 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146319142 Pathogen - hypothetical protein SSU05_1488 1 None None None 146318004 Common - aminotransferase AlaT SSU05_0349 237 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 146319323 Common - ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA SSU05_1669 249 COG1119 ModF, ABC-type molybdenum transport system, ATPase component/photorepair protein PhrA Inorganic ion transport and metabolism 146319587 Common - Transcriptional regulator SSU05_1933 142 COG1737 RpiR, Transcriptional regulators Transcription 146317859 Common - Putative NADH-flavin reductase SSU05_0203 5 COG2910 COG2910, Putative NADH-flavin reductase General function prediction only 146318516 Common - site-specific recombinase, phage integrase family SSU05_0862 65 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146319146 Common - fibronectin/fibrinogen binding protein SSU05_1492 94 COG1293 COG1293, Predicted RNA-binding protein homologous to eukaryotic snRNP Transcription 146319844 Common - Predicted membrane protein SSU05_2190 13 COG3619 COG3619, Predicted membrane protein Function unknown 146319636 Common - Subtilisin-like serine protease SSU05_1982 45 COG1404 AprE, Subtilisin-like serine proteases Posttranslational modification, protein turnover, chaperones 146318724 Common - hypothetical protein SSU05_1070 114 COG2071 COG2071, Predicted glutamine amidotransferases General function prediction only 162139880 Common rpmE2 50S ribosomal protein L31 type B SSU05_1531 161 COG0254 RpmE, Ribosomal protein L31 Translation, ribosomal structure and biogenesis 146319263 Common - IS630-Spn1, transposase Orf2 SSU05_1609 56 COG3335 COG3335, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318825 Common - F0F1-type ATP synthase, epsilon subunit SSU05_1171 117 COG0355 AtpC, F0F1-type ATP synthase, epsilon subunit (mitochondrial delta subunit) Energy production and conversion 146319253 Common - hypothetical protein SSU05_1599 23 COG4922 COG4922, Uncharacterized protein conserved in bacteria Function unknown 146319078 Common - Transposase SSU05_1424 14 COG5433 COG5433, Transposase DNA replication, recombination, and repair 146319455 Common - acetyl-CoA carboxylase biotin carboxyl carrier protein subunit SSU05_1801 170 COG0511 AccB, Biotin carboxyl carrier protein Lipid metabolism 146318498 Common - hypothetical protein SSU05_0844 15 None None None 146318993 Common - ABC-type sugar transport system, permease component SSU05_1339 153 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 146317857 Common - DNA polymerase IV SSU05_0201 185 COG0389 DinP, Nucleotidyltransferase/DNA polymerase involved in DNA repair DNA replication, recombination, and repair 146318560 Common - NisK SSU05_0906 6 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146317987 Common - ABC-type metal ion transport system, periplasmic component/surface adhesin SSU05_0330 162 COG0803 LraI, ABC-type metal ion transport system, periplasmic component/surface adhesin Inorganic ion transport and metabolism 146319013 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain SSU05_1359 199 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146319138 Common - ABC-type uncharacterized transport system, ATPase component SSU05_1484 249 COG1101 PhnK, ABC-type uncharacterized transport system, ATPase component General function prediction only 146317950 Common - hypothetical protein SSU05_0294 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146319486 Common rpsR 30S ribosomal protein S18 SSU05_1832 215 COG0238 RpsR, Ribosomal protein S18 Translation, ribosomal structure and biogenesis 146318260 Common - UDP-galactopyranose mutase SSU05_0606 53 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 146319619 Common - hypothetical protein SSU05_1965 7 COG1862 YajC, Preprotein translocase subunit YajC Intracellular trafficking and secretion 146318118 Common - hypothetical protein SSU05_0464 3 None None None 146318321 Common - Phosphoglycerate dehydrogenase and related dehydrogenase SSU05_0667 231 COG0111 SerA, Phosphoglycerate dehydrogenase and related dehydrogenases Amino acid transport and metabolism 146319825 Common - L-serine deaminase SSU05_2171 149 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 146319046 Common secG preprotein translocase subunit SecG SSU05_1392 6 COG1314 SecG, Preprotein translocase subunit SecG Intracellular trafficking and secretion 146318592 Pathogen - ATPases with chaperone activity, ATP-binding subunit SSU05_0938 1 None None None 146318070 Common recU Holliday junction-specific endonuclease SSU05_0415 17 COG3331 PrfA, Penicillin-binding protein-related factor A, putative recombinase General function prediction only 146317817 Common - Predicted transcriptional regulator SSU05_0159 2 None None None 146318121 Common - asparagine synthetase AsnA SSU05_0467 31 COG2502 AsnA, Asparagine synthetase A Amino acid transport and metabolism 146319082 Common - RNA polymerase sigma factor RpoD SSU05_1428 216 COG0568 RpoD, DNA-directed RNA polymerase, sigma subunit (sigma70/sigma32) Transcription 146317810 Common - elongation factor G SSU05_0152 249 COG0480 FusA, Translation elongation factors (GTPases) Translation, ribosomal structure and biogenesis 146318848 Pathogen - Predicted transcriptional regulator SSU05_1194 1 COG1497 COG1497, Predicted transcriptional regulator Transcription 146319251 Common - hypothetical protein SSU05_1597 5 None None None 146319501 Common - hypothetical protein SSU05_1847 22 COG1358 RPL8A, Ribosomal protein HS6-type (S12/L30/L7a) Translation, ribosomal structure and biogenesis 146318928 Common - hypothetical protein SSU05_1274 2 None None None 146319038 Common - Cation transport ATPase SSU05_1384 122 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 146318696 Common - galactose-6-phosphate isomerase subunit LacB SSU05_1042 128 COG0698 RpiB, Ribose 5-phosphate isomerase RpiB Carbohydrate transport and metabolism 146317763 Pathogen - hypothetical protein SSU05_0105 1 None None None 146318747 Pathogen - hypothetical protein SSU05_1093 1 None None None 146318333 Common - hypothetical protein SSU05_0679 4 None None None 146319341 Common - hypothetical protein SSU05_1687 58 COG0842 COG0842, ABC-type multidrug transport system, permease component Defense mechanisms 146317937 Common - threonine synthase SSU05_0281 133 COG0498 ThrC, Threonine synthase Amino acid transport and metabolism 146317769 Common - ABC-type Mn2+/Zn2+ transport system, permease component SSU05_0111 192 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 146317808 Common rpsL 30S ribosomal protein S12 SSU05_0150 232 COG0048 RpsL, Ribosomal protein S12 Translation, ribosomal structure and biogenesis 146319372 Pathogen - Predicted periplasmic solute-binding protein SSU05_1718 1 None None None 146318742 Common - pantothenate kinase SSU05_1088 91 COG1072 CoaA, Panthothenate kinase Coenzyme metabolism 146318510 Common - Translation initiation factor 1 (IF-1) SSU05_0856 2 None None None 146317796 Common - Cellulase M and related proteins SSU05_0138 79 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 146319089 Common - Predicted sugar phosphatases of the HAD superfamily SSU05_1435 3 COG0647 NagD, Predicted sugar phosphatases of the HAD superfamily Carbohydrate transport and metabolism 146319337 Common - Rhodanese-related sulfurtransferase SSU05_1683 43 COG0607 PspE, Rhodanese-related sulfurtransferase Inorganic ion transport and metabolism 146317787 Common - Type II secretory pathway, pseudopilin PulG SSU05_0129 2 COG2165 PulG, Type II secretory pathway, pseudopilin PulG Cell motility and secretion / Intracellular trafficking and secretion 146318066 Common - Cold shock protein SSU05_0411 180 COG1278 CspC, Cold shock proteins Transcription 146318794 Pathogen - hypothetical protein SSU05_1139 1 None None None 146318599 Pathogen - hypothetical protein SSU05_0945 1 None None None 146318740 Common - pyrimidine-nucleoside phosphorylase SSU05_1086 124 COG0213 DeoA, Thymidine phosphorylase Nucleotide transport and metabolism 146318749 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain SSU05_1095 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146319469 Common - Ribonucleases G and E SSU05_1815 2 COG1426 COG1426, Uncharacterized protein conserved in bacteria Function unknown 146318731 Common - Dihydrofolate reductase SSU05_1077 19 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 146318923 Common rpmI 50S ribosomal protein L35 SSU05_1269 124 COG0291 RpmI, Ribosomal protein L35 Translation, ribosomal structure and biogenesis 146319261 Common - Phosphomannose isomerase SSU05_1607 50 COG1482 ManA, Phosphomannose isomerase Carbohydrate transport and metabolism 146318086 Common - Signal transduction histidine kinase SSU05_0430 150 COG4585 COG4585, Signal transduction histidine kinase Signal transduction mechanisms 146318651 Common rbgA ribosomal biogenesis GTPase SSU05_0997 168 COG1161 COG1161, Predicted GTPases General function prediction only 146319657 Common - hypothetical protein SSU05_2003 5 COG3797 COG3797, Uncharacterized protein conserved in bacteria Function unknown 146318108 Common - Galactose mutarotase and related enzyme SSU05_0454 89 COG2017 GalM, Galactose mutarotase and related enzymes Carbohydrate transport and metabolism 146319162 Common - Phosphoserine phosphatase SSU05_1508 153 COG0560 SerB, Phosphoserine phosphatase Amino acid transport and metabolism 146319168 Common - Virulence-associated protein E SSU05_1514 32 COG3378 COG3378, Predicted ATPase General function prediction only 146317821 Pathogen - hypothetical protein SSU05_0163 1 None None None 146319488 Common - Ribosomal protein S6 SSU05_1834 86 COG0360 RpsF, Ribosomal protein S6 Translation, ribosomal structure and biogenesis 146317666 Common - hypothetical protein SSU05_0004 4 COG4481 COG4481, Uncharacterized protein conserved in bacteria Function unknown 146318151 Common - 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase SSU05_0497 224 COG0190 FolD, 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase Coenzyme metabolism 146317874 Common - ABC-type nitrate/sulfonate/bicarbonate transport system, periplasmic component SSU05_0218 122 COG0715 TauA, ABC-type nitrate/sulfonate/bicarbonate transport systems, periplasmic components Inorganic ion transport and metabolism 146317948 Common - isopentenyl pyrophosphate isomerase SSU05_0292 81 COG1304 LldD, L-lactate dehydrogenase (FMN-dependent) and related alpha-hydroxy acid dehydrogenases Energy production and conversion 146318489 Common - Dihydrofolate reductase SSU05_0835 148 COG0262 FolA, Dihydrofolate reductase Coenzyme metabolism 146319131 Common - hypothetical protein SSU05_1477 1 None None None 146318584 Common - Tn916, transcriptional regulator, putative SSU05_0930 8 COG2946 COG2946, Putative phage replication protein RstA DNA replication, recombination, and repair 146318658 Common - putative glycosyltransferase SSU05_1004 124 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146317816 Common - hypothetical protein SSU05_0158 8 COG4129 COG4129, Predicted membrane protein Function unknown 146319653 Common - Permease of the major facilitator superfamily SSU05_1999 4 None None None 146318633 Common - C-5 cytosine-specific DNA methylase SSU05_0979 134 COG0270 Dcm, Site-specific DNA methylase DNA replication, recombination, and repair 146318974 Common - hypothetical protein SSU05_1320 49 COG0620 MetE, Methionine synthase II (cobalamin-independent) Amino acid transport and metabolism 146318758 Common - ABC-type phosphate transport system, permease component SSU05_1104 230 COG0573 PstC, ABC-type phosphate transport system, permease component Inorganic ion transport and metabolism 146319508 Common - Predicted ABC-type exoprotein transport system, permease component SSU05_1854 12 COG4473 EcsB, Predicted ABC-type exoprotein transport system, permease component Intracellular trafficking and secretion 146317727 Common - Holliday junction resolvase-like protein SSU05_0067 183 COG0816 COG0816, Predicted endonuclease involved in recombination (possible Holliday junction resolvase in Mycoplasmas and B. subtilis) DNA replication, recombination, and repair 146317732 Common rplD 50S ribosomal protein L4 SSU05_0072 216 COG0088 RplD, Ribosomal protein L4 Translation, ribosomal structure and biogenesis 146318550 Common - Carbamoylphosphate synthase large subunit SSU05_0896 12 COG0439 AccC, Biotin carboxylase Lipid metabolism 146317903 Common - hypothetical protein SSU05_0247 7 COG4652 COG4652, Uncharacterized protein conserved in bacteria Function unknown 146319558 Common - hypothetical protein SSU05_1904 4 None None None 146319409 Common - Geranylgeranyl pyrophosphate synthase SSU05_1755 185 COG0142 IspA, Geranylgeranyl pyrophosphate synthase Coenzyme metabolism 146317955 Common - Molecular chaperone GrpE (heat shock protein) SSU05_0299 230 COG0576 GrpE, Molecular chaperone GrpE (heat shock protein) Posttranslational modification, protein turnover, chaperones 146319109 Pathogen - hypothetical protein SSU05_1455 1 None None None 146318627 Common - Type IV secretory pathway, VirD4 component SSU05_0973 72 COG3505 VirD4, Type IV secretory pathway, VirD4 components Intracellular trafficking and secretion 146319624 Common - tRNA-dihydrouridine synthase SSU05_1970 209 COG0042 COG0042, tRNA-dihydrouridine synthase Translation, ribosomal structure and biogenesis 146318845 Common - dsRNA-specific ribonuclease SSU05_1191 216 COG0571 Rnc, dsRNA-specific ribonuclease Transcription 146318482 Common - dihydrodipicolinate reductase SSU05_0828 215 COG0289 DapB, Dihydrodipicolinate reductase Amino acid transport and metabolism 146319763 Pathogen - Ribosomal protein L11 methylase SSU05_2109 1 None None None 146319278 Common - Cellulase M and related proteins SSU05_1624 85 COG1363 FrvX, Cellulase M and related proteins Carbohydrate transport and metabolism 146318900 Common - Methionyl-tRNA synthetase SSU05_1246 99 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146319443 Common - hypothetical protein SSU05_1789 3 COG4733 COG4733, Phage-related protein, tail component Function unknown 146319183 Common - prophage Lp3 protein 1, integrase SSU05_1529 58 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146317678 Common - Signal transduction histidine kinase SSU05_0016 3 None None None 146317919 Common - Predicted membrane protein SSU05_0263 6 COG4709 COG4709, Predicted membrane protein Function unknown 146318873 Common - Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB SSU05_1219 40 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 146319222 Common - hypothetical protein SSU05_1568 2 None None None 146317755 Common - DNA-directed RNA polymerase subunit alpha SSU05_0095 216 COG0202 RpoA, DNA-directed RNA polymerase, alpha subunit/40 kD subunit Transcription 146318407 Common - MRP SSU05_0753 4 COG4717 COG4717, Uncharacterized conserved protein Function unknown 146318365 Common - Phosphotransferase system cellobiose-specific component IIC SSU05_0711 18 COG1455 CelB, Phosphotransferase system cellobiose-specific component IIC Carbohydrate transport and metabolism 146319158 Pathogen - hypothetical protein SSU05_1504 1 None None None 146318323 Common - Arsenate reductase and related proteins, glutaredoxin family SSU05_0669 83 COG1393 ArsC, Arsenate reductase and related proteins, glutaredoxin family Inorganic ion transport and metabolism 146318941 Common - ABC-type polysaccharide/polyol phosphate export system, permease component SSU05_1287 123 COG1682 TagG, ABC-type polysaccharide/polyol phosphate export systems, permease component Carbohydrate transport and metabolism / Cell envelope biogenesis, outer membrane 146318701 Common - Integrase SSU05_1047 28 None None None 146318195 Common - Predicted transcriptional regulator SSU05_0541 91 COG1725 COG1725, Predicted transcriptional regulators Transcription 146319312 Pathogen - hypothetical protein SSU05_1658 1 None None None 146319605 Common - Leucyl aminopeptidase (aminopeptidase T) SSU05_1951 56 COG2309 AmpS, Leucyl aminopeptidase (aminopeptidase T) Amino acid transport and metabolism 146319304 Common - hypothetical protein SSU05_1650 51 COG1307 DegV, Uncharacterized protein conserved in bacteria Function unknown 146318231 Common - Membrane protein involved in the export of O-antigen and teichoic acid SSU05_0577 50 COG2244 RfbX, Membrane protein involved in the export of O-antigen and teichoic acid General function prediction only 146319690 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_2036 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146317898 Common - transcriptional regulator PlcR, putative SSU05_0242 1 COG4496 COG4496, Uncharacterized protein conserved in bacteria Function unknown 146318953 Common - hypothetical protein SSU05_1299 5 None None None 146319193 Common - manganese-dependent superoxide dismutase SSU05_1539 207 COG0605 SodA, Superoxide dismutase Inorganic ion transport and metabolism 146319613 Common - hypothetical protein SSU05_1959 43 COG3412 COG3412, Uncharacterized protein conserved in bacteria Function unknown 146319069 Common - Glycopeptide antibiotics resistance protein SSU05_1415 4 COG4767 VanZ, Glycopeptide antibiotics resistance protein Defense mechanisms 146318647 Common - hypothetical protein SSU05_0993 3 None None None 146317990 Common - DNA-directed RNA polymerase, delta subunit SSU05_0334 12 COG3343 RpoE, DNA-directed RNA polymerase, delta subunit Transcription 146318379 Common - glyoxalase family protein SSU05_0725 37 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 146319735 Common leuS leucyl-tRNA synthetase SSU05_2081 249 COG0495 LeuS, Leucyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146319837 Common - inositol-5-monophosphate dehydrogenase SSU05_2183 240 COG0516 GuaB, IMP dehydrogenase/GMP reductase Nucleotide transport and metabolism 146319806 Common - Predicted phosphohydrolase SSU05_2152 4 COG1409 Icc, Predicted phosphohydrolases General function prediction only 146319596 Pathogen - Acetyltransferase SSU05_1942 1 None None None 146317691 Common - phosphoribosyl glycinamide transformylase-N SSU05_0031 215 COG0299 PurN, Folate-dependent phosphoribosylglycinamide formyltransferase PurN Nucleotide transport and metabolism 146319755 Common - hypothetical protein SSU05_2101 2 None None None 146319494 Common - Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit SSU05_1840 222 COG0022 AcoB, Pyruvate/2-oxoglutarate dehydrogenase complex, dehydrogenase (E1) component, eukaryotic type, beta subunit Energy production and conversion 146319628 Common - transcriptional regulator SSU05_1974 11 COG1056 NadR, Nicotinamide mononucleotide adenylyltransferase Coenzyme metabolism 146318899 Common - Methionyl-tRNA synthetase SSU05_1245 249 COG0143 MetG, Methionyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146319419 Common glyQ glycyl-tRNA synthetase subunit alpha SSU05_1765 167 COG0752 GlyQ, Glycyl-tRNA synthetase, alpha subunit Translation, ribosomal structure and biogenesis 146318979 Common - hypothetical protein SSU05_1325 38 COG2996 COG2996, Uncharacterized protein conserved in bacteria Function unknown 146318051 Common - Metal-dependent hydrolase SSU05_0396 5 COG3568 ElsH, Metal-dependent hydrolase General function prediction only 146317976 Common - Predicted hydrolase or acyltransferases (alpha/beta hydrolase superfamily) SSU05_0320 151 COG0596 MhpC, Predicted hydrolases or acyltransferases (alpha/beta hydrolase superfamily) General function prediction only 146318189 Common - hypothetical protein SSU05_0535 2 COG4506 COG4506, Uncharacterized protein conserved in bacteria Function unknown 146319476 Common - hypothetical protein SSU05_1822 36 COG1302 COG1302, Uncharacterized protein conserved in bacteria Function unknown 146319712 Common araD L-ribulose-5-phosphate 4-epimerase SSU05_2058 133 COG0235 AraD, Ribulose-5-phosphate 4-epimerase and related epimerases and aldolases Carbohydrate transport and metabolism 146318909 Common - ABC-type uncharacterized transport system, permease component SSU05_1255 45 COG4120 COG4120, ABC-type uncharacterized transport system, permease component General function prediction only 146318890 Common alaS alanyl-tRNA synthetase SSU05_1236 249 COG0013 AlaS, Alanyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146319449 Pathogen - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_1795 1 None None None 146317846 Common - Phosphotransferase system, galactitol-specific IIB component SSU05_0188 28 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 146319137 Common - hypothetical protein SSU05_1483 2 COG3760 COG3760, Uncharacterized conserved protein Function unknown 146318370 Common - Glycerol dehydrogenase and related enzyme SSU05_0716 4 COG0371 GldA, Glycerol dehydrogenase and related enzymes Energy production and conversion 146318772 Common - hypothetical protein SSU05_1118 23 COG2461 COG2461, Uncharacterized conserved protein Function unknown 146317704 Pathogen - hypothetical protein SSU05_0044 1 None None None 146318428 Common - Threonine aldolase SSU05_0774 71 COG2008 GLY1, Threonine aldolase Amino acid transport and metabolism 146319060 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_1406 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146317997 Common - RecG-like helicase SSU05_0342 211 COG1200 RecG, RecG-like helicase DNA replication, recombination, and repair / Transcription 146319652 Common - Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily SSU05_1998 24 COG1368 MdoB, Phosphoglycerol transferase and related proteins, alkaline phosphatase superfamily Cell envelope biogenesis, outer membrane 146317697 Common - hypothetical protein SSU05_0037 3 None None None 146318218 Common - Cps2A SSU05_0564 61 COG1316 LytR, Transcriptional regulator Transcription 146319008 Common - Cell division protein FtsI/penicillin-binding protein 2 SSU05_1354 189 COG0768 FtsI, Cell division protein FtsI/penicillin-binding protein 2 Cell envelope biogenesis, outer membrane 146318302 Common - ABC-type Fe3+-hydroxamate transport system, periplasmic component SSU05_0649 60 COG0614 FepB, ABC-type Fe3+-hydroxamate transport system, periplasmic component Inorganic ion transport and metabolism 146318764 Common - hypothetical protein SSU05_1110 11 COG4476 COG4476, Uncharacterized protein conserved in bacteria Function unknown 146319057 Common - hemolysin SSU05_1403 7 None None None 146319585 Common - pts system, sucrose-specific iibc component SSU05_1931 42 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 146319525 Common - ABC-type transport system involved in Fe-S cluster assembly, permease component SSU05_1871 187 COG0719 SufB, ABC-type transport system involved in Fe-S cluster assembly, permease component Posttranslational modification, protein turnover, chaperones 146319259 Common - prolipoprotein diacylglyceryl transferase SSU05_1605 209 COG0682 Lgt, Prolipoprotein diacylglyceryltransferase Cell envelope biogenesis, outer membrane 146319050 Common - formamidopyrimidine-DNA glycosylase SSU05_1396 182 COG0266 Nei, Formamidopyrimidine-DNA glycosylase DNA replication, recombination, and repair 146319144 Common - Phosphotransferase system IIC component, glucose/maltose/N-acetylglucosamine-specific SSU05_1490 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 146319473 Common - Transcriptional regulator SSU05_1819 128 COG1609 PurR, Transcriptional regulators Transcription 146318773 Common - hypothetical protein SSU05_1119 6 None None None 146318600 Common - cdd4 SSU05_0946 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146318902 Pathogen - hypothetical protein SSU05_1248 1 None None None 146317699 Common - adenylosuccinate lyase SSU05_0039 239 COG0015 PurB, Adenylosuccinate lyase Nucleotide transport and metabolism 146319148 Common - TPR repeat protein SSU05_1494 1 None None None 146318698 Pathogen - hypothetical protein SSU05_1044 1 None None None 146317908 Common - glutamate dehydrogenase SSU05_0252 166 COG0334 GdhA, Glutamate dehydrogenase/leucine dehydrogenase Amino acid transport and metabolism 146318048 Common - 4-alpha-glucanotransferase SSU05_0393 52 COG1640 MalQ, 4-alpha-glucanotransferase Carbohydrate transport and metabolism 146319575 Common - Putative alpha-1,2-mannosidase SSU05_1921 26 COG3537 COG3537, Putative alpha-1,2-mannosidase Carbohydrate transport and metabolism 146318566 Common - putative asparagine synthetase SSU05_0912 5 COG0367 AsnB, Asparagine synthase (glutamine-hydrolyzing) Amino acid transport and metabolism 146319209 Common - Glycosidase SSU05_1555 79 COG0366 AmyA, Glycosidases Carbohydrate transport and metabolism 146319418 Common glyS glycyl-tRNA synthetase subunit beta SSU05_1764 167 COG0751 GlyS, Glycyl-tRNA synthetase, beta subunit Translation, ribosomal structure and biogenesis 146317822 Common - putative molecular chaperone SSU05_0164 160 COG1214 COG1214, Inactive homolog of metal-dependent proteases, putative molecular chaperone Posttranslational modification, protein turnover, chaperones 146319771 Common - hypothetical protein SSU05_2117 1 None None None 146319846 Common - Trypsin-like serine protease, typically periplasmic, contain C-terminal PDZ domain SSU05_2192 222 COG0265 DegQ, Trypsin-like serine proteases, typically periplasmic, contain C-terminal PDZ domain Posttranslational modification, protein turnover, chaperones 146319461 Common - 3-oxoacyl-(acyl carrier protein) synthase III SSU05_1807 223 COG0332 FabH, 3-oxoacyl- acyl-carrier-protein 146318622 Common - Tn5252, Orf28 SSU05_0968 9 COG3942 COG3942, Surface antigen General function prediction only 146319561 Common - ABC-type sugar transport system, ATPase component SSU05_1907 249 COG3839 MalK, ABC-type sugar transport systems, ATPase components Carbohydrate transport and metabolism 146318397 Common - Predicted hydrolase (HAD superfamily) SSU05_0743 69 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 146317768 Common - ABC-type Mn/Zn transport system, ATPase component SSU05_0110 249 COG1121 ZnuC, ABC-type Mn/Zn transport systems, ATPase component Inorganic ion transport and metabolism 146319458 Common - (acyl-carrier-protein) S-malonyltransferase SSU05_1804 209 COG0331 FabD, (acyl-carrier-protein) S-malonyltransferase Lipid metabolism 146318468 Common - Predicted EndoIII-related endonuclease SSU05_0813 238 COG0177 Nth, Predicted EndoIII-related endonuclease DNA replication, recombination, and repair 146318390 Common - hypothetical protein SSU05_0736 92 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 146319593 Pathogen - hypothetical protein SSU05_1939 1 None None None 146319001 Common - Peptide chain release factor RF-3 SSU05_1347 249 COG4108 PrfC, Peptide chain release factor RF-3 Translation, ribosomal structure and biogenesis 146317790 Pathogen - hypothetical protein SSU05_0132 1 None None None 146318793 Common - D-beta-hydroxybutyrate permease SSU05_1140 34 COG2610 GntT, H+/gluconate symporter and related permeases Carbohydrate transport and metabolism / Amino acid transport and metabolism 146318786 Common - Predicted membrane protein SSU05_1132 3 COG4709 COG4709, Predicted membrane protein Function unknown 146318535 Common xerS site-specific tyrosine recombinase XerS SSU05_0881 216 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146319411 Common - NADH dehydrogenase, FAD-containing subunit SSU05_1757 177 COG1252 Ndh, NADH dehydrogenase, FAD-containing subunit Energy production and conversion 146319305 Common - ATPase involved in DNA repair SSU05_1651 219 COG0497 RecN, ATPase involved in DNA repair DNA replication, recombination, and repair 146318442 Common - hypothetical protein SSU05_0788 1 None None None 146319246 Common - transposase of IS200 family SSU05_1592 73 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318095 Pathogen - hypothetical protein SSU05_0441 1 None None None 146319678 Common mmuM homocysteine methyltransferase SSU05_2024 148 COG2040 MHT1, Homocysteine/selenocysteine methylase (S-methylmethionine-dependent) Amino acid transport and metabolism 146318248 Pathogen - ATPase involved in DNA repair SSU05_0594 1 None None None 146318562 Pathogen - hypothetical protein SSU05_0908 1 None None None 146318261 Common - Predicted flavoprotein SSU05_0607 1 COG0431 COG0431, Predicted flavoprotein General function prediction only 146319796 Common - Predicted acyltransferase SSU05_2142 95 COG2153 ElaA, Predicted acyltransferase General function prediction only 146318372 Common - aspartate-semialdehyde dehydrogenase SSU05_0718 232 COG0136 Asd, Aspartate-semialdehyde dehydrogenase Amino acid transport and metabolism 146317896 Common - Peptide methionine sulfoxide reductase SSU05_0240 206 COG0229 COG0229, Conserved domain frequently associated with peptide methionine sulfoxide reductase Posttranslational modification, protein turnover, chaperones 146318834 Common ligA NAD-dependent DNA ligase LigA SSU05_1180 219 COG0272 Lig, NAD-dependent DNA ligase (contains BRCT domain type II) DNA replication, recombination, and repair 146319299 Common - Transposase and inactivated derivative SSU05_1645 39 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 146319076 Common - hypothetical protein SSU05_1422 14 COG0398 COG0398, Uncharacterized conserved protein Function unknown 146317927 Common - NTP pyrophosphohydrolase including oxidative damage repair enzyme SSU05_0271 88 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146319647 Common - Pentose-5-phosphate-3-epimerase SSU05_1993 216 COG0036 Rpe, Pentose-5-phosphate-3-epimerase Carbohydrate transport and metabolism 146317834 Common - Predicted membrane protein SSU05_0176 118 COG2855 COG2855, Predicted membrane protein Function unknown 146319062 Common - Fe2+ transport system protein A SSU05_1408 54 COG1918 FeoA, Fe2+ transport system protein A Inorganic ion transport and metabolism 146318279 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_0625 63 COG2153 ElaA, Predicted acyltransferase General function prediction only 146319764 Common - hypothetical protein SSU05_2110 8 COG4043 COG4043, Uncharacterized conserved protein Function unknown 146319191 Common - hypothetical protein SSU05_1537 82 COG0038 EriC, Chloride channel protein EriC Inorganic ion transport and metabolism 146318885 Pathogen - hypothetical protein SSU05_1231 1 None None None 146319367 Pathogen - hypothetical protein SSU05_1712 1 None None None 146318227 Common - Cps2J SSU05_0573 162 COG0463 WcaA, Glycosyltransferases involved in cell wall biogenesis Cell envelope biogenesis, outer membrane 146317947 Common - Mevalonate kinase SSU05_0291 21 COG1577 ERG12, Mevalonate kinase Lipid metabolism 146318918 Common - Predicted SAM-dependent methyltransferase SSU05_1264 130 COG1092 COG1092, Predicted SAM-dependent methyltransferases General function prediction only 146319220 Common - Predicted O-methyltransferase SSU05_1566 84 COG4123 COG4123, Predicted O-methyltransferase General function prediction only 146318259 Common - UDP-galactopyranose mutase SSU05_0605 52 COG0562 Glf, UDP-galactopyranose mutase Cell envelope biogenesis, outer membrane 146319405 Common - hypothetical protein SSU05_1751 11 COG5341 COG5341, Uncharacterized protein conserved in bacteria Function unknown 146318169 Common - ABC-type antimicrobial peptide transport system, ATPase component SSU05_0515 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 146319644 Common - Predicted HD-superfamily hydrolase SSU05_1990 47 COG3481 COG3481, Predicted HD-superfamily hydrolase General function prediction only 146317719 Common mutL DNA mismatch repair protein SSU05_0059 191 COG0323 MutL, DNA mismatch repair enzyme (predicted ATPase) DNA replication, recombination, and repair 146319749 Common - 2',3'-cyclic nucleotide 2'-phosphodiesterase/3'-nucleotidase bifunctional periplasmic precursor protein SSU05_2095 129 COG0737 UshA, 5'-nucleotidase/2',3'-cyclic phosphodiesterase and related esterases Nucleotide transport and metabolism 146318541 Pathogen - hypothetical protein SSU05_0887 1 None None None 146319016 Common - ABC transporter substrate-binding protein - glutamine transport/Major cell binding factor precursor SSU05_1362 178 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146318685 Pathogen - hypothetical protein SSU05_1032 1 None None None 146319388 Common - 6-phosphogluconate dehydrogenase SSU05_1734 135 COG0362 Gnd, 6-phosphogluconate dehydrogenase Carbohydrate transport and metabolism 146318861 Common - ribonucleotide-diphosphate reductase subunit alpha SSU05_1207 217 COG0209 NrdA, Ribonucleotide reductase, alpha subunit Nucleotide transport and metabolism 146318445 Common - carbamoyl phosphate synthase small subunit SSU05_0791 237 COG0505 CarA, Carbamoylphosphate synthase small subunit Amino acid transport and metabolism / Nucleotide transport and metabolism 146317887 Common - Phosphotransferase system IIC component, glucose/maltose/N-acetylglucosamine-specific SSU05_0231 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 146319714 Common ulaD 3-keto-L-gulonate-6-phosphate decarboxylase SSU05_2060 47 COG0269 SgbH, 3-hexulose-6-phosphate synthase and related proteins Carbohydrate transport and metabolism 146319836 Common recF recombination protein F SSU05_2182 170 COG1195 RecF, Recombinational DNA repair ATPase (RecF pathway) DNA replication, recombination, and repair 146319630 Common - transcriptional regulator CtsR SSU05_1976 22 COG4463 CtsR, Transcriptional repressor of class III stress genes Transcription 146318968 Common - HrpA-like helicase SSU05_1314 3 COG4468 GalT, Galactose-1-phosphate uridyltransferase Carbohydrate transport and metabolism 146317733 Common rplW 50S ribosomal protein L23 SSU05_0073 188 COG0089 RplW, Ribosomal protein L23 Translation, ribosomal structure and biogenesis 146318331 Common - Predicted integral membrane protein SSU05_0677 7 COG5523 COG5523, Predicted integral membrane protein Function unknown 146317875 Common - 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase SSU05_0219 75 COG0363 NagB, 6-phosphogluconolactonase/Glucosamine-6-phosphate isomerase/deaminase Carbohydrate transport and metabolism 146317771 Common - Predicted transcriptional regulator SSU05_0113 23 COG3682 COG3682, Predicted transcriptional regulator Transcription 146319724 Common - Surface antigen SSU05_2070 8 COG3942 COG3942, Surface antigen General function prediction only 146319741 Common - putative metal-dependent transcriptional regulator SSU05_2087 58 COG1321 TroR, Mn-dependent transcriptional regulator Transcription 146319202 Common - hypothetical protein SSU05_1548 141 COG0683 LivK, ABC-type branched-chain amino acid transport systems, periplasmic component Amino acid transport and metabolism 146319330 Pathogen - hypothetical protein SSU05_1675 1 None None None 146318150 Common - putative amino acid ABC transporter, ATP-binding protein SSU05_0496 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 146318898 Common - Competence protein SSU05_1244 12 COG4469 CoiA, Competence protein General function prediction only 146318432 Common - Branched-chain amino acid permease SSU05_0778 46 COG1114 BrnQ, Branched-chain amino acid permeases Amino acid transport and metabolism 146318609 Common - hypothetical protein SSU05_0955 16 COG1708 COG1708, Predicted nucleotidyltransferases General function prediction only 146319453 Common - acetyl-CoA carboxylase biotin carboxylase subunit SSU05_1799 236 COG0439 AccC, Biotin carboxylase Lipid metabolism 146318347 Common - putative HsdR SSU05_0693 142 COG0610 COG0610, Type I site-specific restriction-modification system, R (restriction) subunit and related helicases Defense mechanisms 146318284 Common - N-acetyl-beta-hexosaminidase SSU05_0630 51 COG3525 Chb, N-acetyl-beta-hexosaminidase Carbohydrate transport and metabolism 146319011 Common - Metal-dependent hydrolases of the beta-lactamase superfamily I SSU05_1357 59 COG1235 PhnP, Metal-dependent hydrolases of the beta-lactamase superfamily I General function prediction only 146317863 Pathogen - hypothetical protein SSU05_0207 1 None None None 146318805 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_1151 46 COG0456 RimI, Acetyltransferases General function prediction only 146318075 Common - S-ribosylhomocysteinase SSU05_0420 55 COG1854 LuxS, LuxS protein involved in autoinducer AI2 synthesis Signal transduction mechanisms 146318055 Pathogen - hypothetical protein SSU05_0400 1 None None None 146318669 Common - Glycogen synthase SSU05_1015 143 COG0297 GlgA, Glycogen synthase Carbohydrate transport and metabolism 146318652 Common - Predicted Fe-S-cluster oxidoreductase SSU05_0998 13 COG0727 COG0727, Predicted Fe-S-cluster oxidoreductase General function prediction only 146318545 Common - ABC-type antimicrobial peptide transport system, ATPase component SSU05_0891 249 COG1136 SalX, ABC-type antimicrobial peptide transport system, ATPase component Defense mechanisms 146318577 Common - Tn916, hypothetical protein SSU05_0923 6 None None None 146318144 Common - hypothetical protein SSU05_0490 3 None None None 146318643 Common - Acetyltransferase (isoleucine patch superfamily) SSU05_0989 91 COG0110 WbbJ, Acetyltransferase (isoleucine patch superfamily) General function prediction only 146319225 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_1571 42 COG0456 RimI, Acetyltransferases General function prediction only 146319310 Common xseA exodeoxyribonuclease VII large subunit SSU05_1656 205 COG1570 XseA, Exonuclease VII, large subunit DNA replication, recombination, and repair 146318346 Common - pyridine nucleotide-disulfide oxidoreductase SSU05_0692 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 146319252 Common - transaminase SSU05_1598 240 COG0436 COG0436, Aspartate/tyrosine/aromatic aminotransferase Amino acid transport and metabolism 146319181 Common - Predicted transcriptional regulator SSU05_1527 21 COG1476 COG1476, Predicted transcriptional regulators Transcription 146318037 Common - hypothetical protein SSU05_0382 7 None None None 146318972 Common - Cyanate permease SSU05_1318 30 COG2807 CynX, Cyanate permease Inorganic ion transport and metabolism 146317799 Common - Predicted secreted protein SSU05_0141 12 COG4086 COG4086, Predicted secreted protein Function unknown 146318854 Common - Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) SSU05_1200 235 COG1080 PtsA, Phosphoenolpyruvate-protein kinase (PTS system EI component in bacteria) Carbohydrate transport and metabolism 146317759 Common - hypothetical protein SSU05_0101 6 None None None 146319729 Common - Phosphotransferase system cellobiose-specific component IIB SSU05_2075 31 COG1440 CelA, Phosphotransferase system cellobiose-specific component IIB Carbohydrate transport and metabolism 146318833 Common - putative lipid kinase SSU05_1179 104 COG1597 LCB5, Sphingosine kinase and enzymes related to eukaryotic diacylglycerol kinase Lipid metabolism / General function prediction only 146318133 Common - Actin-like ATPase involved in cell division SSU05_0479 137 COG0849 FtsA, Actin-like ATPase involved in cell division Cell division and chromosome partitioning 146319044 Common smpB SsrA-binding protein SSU05_1390 216 COG0691 SmpB, tmRNA-binding protein Posttranslational modification, protein turnover, chaperones 146319025 Common - Ribonucleases G and E SSU05_1371 27 None None None 146318030 Common - SAM-dependent methyltransferase SSU05_0375 115 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146319112 Common - hypothetical protein SSU05_1458 6 COG1704 LemA, Uncharacterized conserved protein Function unknown 146319699 Common - Tetrahydrodipicolinate N-succinyltransferase SSU05_2046 231 COG2171 DapD, Tetrahydrodipicolinate N-succinyltransferase Amino acid transport and metabolism 146318815 Pathogen - Transcriptional regulator SSU05_1161 1 None None None 146319543 Common - Thiamine pyrophosphate-requiring enzyme SSU05_1889 193 COG0028 IlvB, Thiamine pyrophosphate-requiring enzymes [acetolactate synthase, pyruvate dehydrogenase (cytochrome), glyoxylate carboligase, phosphonopyruvate decarboxylase] Amino acid transport and metabolism / Coenzyme metabolism 146319815 Common - Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain SSU05_2161 36 COG3887 COG3887, Predicted signaling protein consisting of a modified GGDEF domain and a DHH domain Signal transduction mechanisms 146319848 Pathogen - Predicted transcriptional regulator SSU05_2194 1 None None None 146319235 Common - 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase SSU05_1581 108 COG0775 Pfs, Nucleoside phosphorylase Nucleotide transport and metabolism 146319244 Common - Predicted transcriptional regulator SSU05_1590 68 COG1695 COG1695, Predicted transcriptional regulators Transcription 146318355 Common - Sortase and related acyltransferase SSU05_0701 116 COG1247 COG1247, Sortase and related acyltransferases Cell envelope biogenesis, outer membrane 146319611 Common - Dihydroxyacetone kinase SSU05_1957 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 146318013 Common - deoxyguanosinetriphosphate triphosphohydrolase-related protein SSU05_0358 137 COG0232 Dgt, dGTP triphosphohydrolase Nucleotide transport and metabolism 146319293 Pathogen - hypothetical protein SSU05_1639 1 None None None 146318528 Common - Transcriptional regulator SSU05_0874 141 COG2188 PhnF, Transcriptional regulators Transcription 146318457 Common - homoserine kinase SSU05_0803 121 COG0083 ThrB, Homoserine kinase Amino acid transport and metabolism 146318311 Pathogen - hypothetical protein SSU05_0657 1 None None None 146319126 Common - Predicted glutamine amidotransferase SSU05_1472 49 COG3442 COG3442, Predicted glutamine amidotransferase General function prediction only 146319538 Common - Membrane protease subunit SSU05_1884 199 COG0330 HflC, Membrane protease subunits, stomatin/prohibitin homologs Posttranslational modification, protein turnover, chaperones 146319683 Common - hypothetical protein SSU05_2029 4 None None None 146317850 Common - hypothetical protein SSU05_0194 97 COG0718 COG0718, Uncharacterized protein conserved in bacteria Function unknown 146318641 Common - Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake SSU05_0987 207 COG0758 Smf, Predicted Rossmann fold nucleotide-binding protein involved in DNA uptake DNA replication, recombination, and repair / Intracellular trafficking and secretion 146318930 Common - hypothetical protein SSU05_1276 8 COG2456 COG2456, Uncharacterized conserved protein Function unknown 146319275 Common - S-adenosylmethionine synthetase SSU05_1621 213 COG0192 MetK, S-adenosylmethionine synthetase Coenzyme metabolism 146317757 Common - Ribosomal protein L17 SSU05_0097 203 COG0203 RplQ, Ribosomal protein L17 Translation, ribosomal structure and biogenesis 146317916 Common - Transcriptional regulator SSU05_0260 27 COG1309 AcrR, Transcriptional regulator Transcription 146318874 Common - hypothetical protein SSU05_1220 19 None None None 146319474 Common - Transcription termination factor SSU05_1820 136 COG0781 NusB, Transcription termination factor Transcription 146318180 Common - cell division membrane protein SSU05_0526 203 COG0772 FtsW, Bacterial cell division membrane protein Cell division and chromosome partitioning 146319213 Common - Alpha-galactosidase SSU05_1560 46 COG3345 GalA, Alpha-galactosidase Carbohydrate transport and metabolism 146319151 Common - 3-carboxymuconate cyclase SSU05_1497 57 COG2706 COG2706, 3-carboxymuconate cyclase Carbohydrate transport and metabolism 146319831 Common - CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase SSU05_2177 207 COG0558 PgsA, Phosphatidylglycerophosphate synthase Lipid metabolism 146318570 Common - putative Abi-alpha protein SSU05_0916 3 COG2865 COG2865, Predicted transcriptional regulator containing an HTH domain and an uncharacterized domain shared with the mammalian protein Schlafen Transcription 146318586 Common - hypothetical protein SSU05_0932 6 None None None 146317995 Common - Fructose/tagatose bisphosphate aldolase SSU05_0339 2 COG0191 Fba, Fructose/tagatose bisphosphate aldolase Carbohydrate transport and metabolism 146318937 Pathogen - hypothetical protein SSU05_1283 1 None None None 146319667 Common - Predicted RNA-binding protein SSU05_2013 62 COG1847 Jag, Predicted RNA-binding protein General function prediction only 146319514 Common - Predicted ATPase or kinase SSU05_1860 197 COG0802 COG0802, Predicted ATPase or kinase General function prediction only 146319696 Common - hypothetical protein SSU05_2042 107 COG0705 GlpG, Uncharacterized membrane protein (homolog of Drosophila rhomboid) General function prediction only 146318601 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_0947 247 COG2274 SunT, ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain Defense mechanisms 146319726 Common - hypothetical protein SSU05_2072 2 None None None 146318018 Common - Uncharacterized protein involved in copper resistance SSU05_0363 56 COG3142 CutC, Uncharacterized protein involved in copper resistance Inorganic ion transport and metabolism 146318139 Common - Predicted integral membrane protein SSU05_0485 2 None None None 146319808 Common - Succinate dehydrogenase/fumarate reductase, flavoprotein subunit SSU05_2154 203 COG1053 SdhA, Succinate dehydrogenase/fumarate reductase, flavoprotein subunit Energy production and conversion 146317891 Common - Mismatch repair ATPase (MutS family) SSU05_0235 206 COG1193 COG1193, Mismatch repair ATPase (MutS family) DNA replication, recombination, and repair 146318483 Common - tRNA CCA-pyrophosphorylase SSU05_0829 214 COG0617 PcnB, tRNA nucleotidyltransferase/poly(A) polymerase Translation, ribosomal structure and biogenesis 146318178 Common - Lyzozyme M1 (1,4-beta-N-acetylmuramidase) SSU05_0524 9 COG3757 Acm, Lyzozyme M1 (1,4-beta-N-acetylmuramidase) Cell envelope biogenesis, outer membrane 146318373 Common - dihydrodipicolinate synthase SSU05_0719 235 COG0329 DapA, Dihydrodipicolinate synthase/N-acetylneuraminate lyase Amino acid transport and metabolism / Cell envelope biogenesis, outer membrane 146317684 Common - fatty acid/phospholipid synthesis protein SSU05_0024 177 COG0416 PlsX, Fatty acid/phospholipid biosynthesis enzyme Lipid metabolism 146318948 Common - N-acetylmuramoyl-L-alanine amidase SSU05_1294 184 COG0860 AmiC, N-acetylmuramoyl-L-alanine amidase Cell envelope biogenesis, outer membrane 146319371 Common - Predicted periplasmic solute-binding protein SSU05_1717 186 COG1559 COG1559, Predicted periplasmic solute-binding protein General function prediction only 146318475 Common - Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase SSU05_0821 238 COG0079 HisC, Histidinol-phosphate/aromatic aminotransferase and cobyric acid decarboxylase Amino acid transport and metabolism 146318255 Common - Prephenate dehydratase SSU05_0601 195 COG0077 PheA, Prephenate dehydratase Amino acid transport and metabolism 146318072 Common - Cell division initiation protein SSU05_0417 14 COG3599 DivIVA, Cell division initiation protein Cell division and chromosome partitioning 146319706 Pathogen - hypothetical protein SSU05_2052 1 None None None 146318632 Pathogen - hypothetical protein SSU05_0978 1 None None None 146318050 Common - Transcriptional regulator SSU05_0395 80 COG2188 PhnF, Transcriptional regulators Transcription 146318958 Common - Predicted SAM-dependent methyltransferase SSU05_1304 32 COG2384 COG2384, Predicted SAM-dependent methyltransferase General function prediction only 146318057 Common - hypothetical protein SSU05_0402 212 COG0217 COG0217, Uncharacterized conserved protein Function unknown 146318664 Common - putative dihydroorotate dehydrogenase B SSU05_1010 140 COG0167 PyrD, Dihydroorotate dehydrogenase Nucleotide transport and metabolism 146317728 Common - hypothetical protein SSU05_0068 14 COG3906 COG3906, Uncharacterized protein conserved in bacteria Function unknown 146318340 Common - Phosphomannomutase SSU05_0686 237 COG1109 {ManB}, Phosphomannomutase Carbohydrate transport and metabolism 146318708 Common - ABC-type multidrug transport system, ATPase and permease component SSU05_1054 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146317913 Common - ABC-type uncharacterized transport system, permease component SSU05_0257 38 COG4587 COG4587, ABC-type uncharacterized transport system, permease component General function prediction only 146318233 Common - UDP-N-acetylglucosamine 2-epimerase SSU05_0579 62 COG0381 WecB, UDP-N-acetylglucosamine 2-epimerase Cell envelope biogenesis, outer membrane 146318230 Pathogen - hypothetical protein SSU05_0576 1 None None None 146319732 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase SSU05_2078 103 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 146318409 Common - ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) SSU05_0755 228 COG1074 RecB, ATP-dependent exoDNAse (exonuclease V) beta subunit (contains helicase and exonuclease domains) DNA replication, recombination, and repair 146319393 Common - Superfamily II DNA and RNA helicase SSU05_1739 236 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 146319766 Pathogen - hypothetical protein SSU05_2112 2 None None None 146318130 Common murD UDP-N-acetylmuramoyl-L-alanyl-D-glutamate synthetase SSU05_0476 211 COG0771 MurD, UDP-N-acetylmuramoylalanine-D-glutamate ligase Cell envelope biogenesis, outer membrane 146319155 Pathogen - hypothetical protein SSU05_1501 4 None None None 146318977 Common - hypothetical protein SSU05_1323 7 None None None 146318775 Common - Transposase and inactivated derivative SSU05_1121 12 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 146319757 Pathogen - hypothetical protein SSU05_2102 1 None None None 146319436 Common - Seryl-tRNA synthetase SSU05_1782 244 COG0172 SerS, Seryl-tRNA synthetase Translation, ribosomal structure and biogenesis 146319175 Pathogen - hypothetical protein SSU05_1521 1 None None None 146318864 Common - Transcriptional regulator SSU05_1210 119 COG1609 PurR, Transcriptional regulators Transcription 146318106 Common - Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID SSU05_0452 40 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 146317931 Pathogen - hypothetical protein SSU05_0275 1 None None None 146318517 Common - hypothetical protein SSU05_0863 5 None None None 146317906 Common - Small-conductance mechanosensitive channel SSU05_0250 112 COG0668 MscS, Small-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 146319673 Common - hypothetical protein SSU05_2019 4 None None None 146319783 Pathogen - Permease of the major facilitator superfamily SSU05_2129 1 None None None 146318170 Common - ABC-type antimicrobial peptide transport system, permease component SSU05_0516 41 COG0577 SalY, ABC-type antimicrobial peptide transport system, permease component Defense mechanisms 146318164 Common - hypothetical protein SSU05_0510 58 COG1878 COG1878, Predicted metal-dependent hydrolase General function prediction only 146318617 Pathogen - hypothetical protein SSU05_0963 1 None None None 146318082 Common - Serine/threonine protein phosphatase SSU05_0427 135 COG0631 PTC1, Serine/threonine protein phosphatase Signal transduction mechanisms 146319779 Common - Arginine repressor SSU05_2125 76 COG1438 ArgR, Arginine repressor Transcription 146318153 Common - putative signal peptidase IB SSU05_0499 73 COG0681 LepB, Signal peptidase I Intracellular trafficking and secretion 146319351 Common - rRNA methyltransferase, TrmH family SSU05_1697 143 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 146318313 Common - hypothetical protein SSU05_0659 47 COG1284 COG1284, Uncharacterized conserved protein Function unknown 146317876 Common - Cation transport ATPase SSU05_0220 230 COG2217 ZntA, Cation transport ATPase Inorganic ion transport and metabolism 146318291 Pathogen - hypothetical protein SSU05_0636 1 None None None 146319378 Pathogen - hypothetical protein SSU05_1724 1 None None None 146318637 Common - Ribosomal protein L7/L12 SSU05_0983 210 COG0222 RplL, Ribosomal protein L7/L12 Translation, ribosomal structure and biogenesis 146318737 Common - Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein SSU05_1083 96 COG1744 Med, Uncharacterized ABC-type transport system, periplasmic component/surface lipoprotein General function prediction only 146318187 Common - HD superfamily phosphohydrolase SSU05_0533 88 COG1078 COG1078, HD superfamily phosphohydrolases General function prediction only 146318085 Pathogen - hypothetical protein SSU05_0431 1 None None None 146318769 Common - Pseudouridine synthase SSU05_1115 8 COG0130 TruB, Pseudouridine synthase Translation, ribosomal structure and biogenesis 146318339 Common - transposase of IS200 family SSU05_0685 72 COG1943 COG1943, Transposase and inactivated derivatives DNA replication, recombination, and repair 146317673 Pathogen - hypothetical protein SSU05_0011 1 None None None 146318612 Common - putative adenine phosphoribosyltransferase SSU05_0958 162 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 146319096 Pathogen - hypothetical protein SSU05_1442 1 None None None 146318986 Common rplK 50S ribosomal protein L11 SSU05_1332 246 COG0080 RplK, Ribosomal protein L11 Translation, ribosomal structure and biogenesis 146319485 Common - hypothetical protein SSU05_1831 8 COG4858 COG4858, Uncharacterized membrane-bound protein conserved in bacteria Function unknown 146319171 Pathogen - hypothetical protein SSU05_1517 1 None None None 146318003 Common - Universal stress protein UspA and related nucleotide-binding protein SSU05_0348 41 COG0589 UspA, Universal stress protein UspA and related nucleotide-binding proteins Signal transduction mechanisms 146318552 Common - Predicted hydrolase of the alpha/beta superfamily SSU05_0898 33 COG2819 COG2819, Predicted hydrolase of the alpha/beta superfamily General function prediction only 146319165 Common - Putative intracellular protease/amidase SSU05_1511 146 COG0693 ThiJ, Putative intracellular protease/amidase General function prediction only 146319664 Common - Small primase-like proteins (Toprim domain) SSU05_2010 21 COG1658 COG1658, Small primase-like proteins (Toprim domain) DNA replication, recombination, and repair 146317751 Common adk adenylate kinase SSU05_0091 229 COG0563 Adk, Adenylate kinase and related kinases Nucleotide transport and metabolism 146318061 Common - hypothetical protein SSU05_0406 111 COG1054 COG1054, Predicted sulfurtransferase General function prediction only 146317855 Common - Beta-lactamase class C and other penicillin binding proteins SSU05_0199 60 COG1680 AmpC, Beta-lactamase class C and other penicillin binding proteins Defense mechanisms 146317744 Common rpsH 30S ribosomal protein S8 SSU05_0084 248 COG0096 RpsH, Ribosomal protein S8 Translation, ribosomal structure and biogenesis 146318913 Common - N-acetylglucosamine-6-phosphate deacetylase SSU05_1259 118 COG1820 NagA, N-acetylglucosamine-6-phosphate deacetylase Carbohydrate transport and metabolism 146317815 Common pgk phosphoglycerate kinase SSU05_0157 247 COG0126 Pgk, 3-phosphoglycerate kinase Carbohydrate transport and metabolism 146318068 Pathogen - hypothetical protein SSU05_0413 1 None None None 146319133 Common - Predicted esterase SSU05_1479 38 COG0627 COG0627, Predicted esterase General function prediction only 146318530 Common - Signal recognition particle GTPase SSU05_0876 247 COG0541 Ffh, Signal recognition particle GTPase Intracellular trafficking and secretion 146318264 Common - Transposase and inactivated derivative SSU05_0610 7 None None None 146319036 Pathogen - Superfamily I DNA and RNA helicase SSU05_1382 1 None None None 146318656 Common pyrC dihydroorotase SSU05_1002 212 COG0044 PyrC, Dihydroorotase and related cyclic amidohydrolases Nucleotide transport and metabolism 146318813 Common - Glucuronate isomerase SSU05_1159 59 COG1904 UxaC, Glucuronate isomerase Carbohydrate transport and metabolism 146319282 Common - GAF domain-containing protein SSU05_1628 74 COG1956 COG1956, GAF domain-containing protein Signal transduction mechanisms 146319167 Common - prophage LambdaSa2, site-specific recombinase, phage integrase family SSU05_1513 70 COG4973 XerC, Site-specific recombinase XerC DNA replication, recombination, and repair 146319200 Common - ABC-type branched-chain amino acid transport system, permease component SSU05_1546 159 COG4177 LivM, ABC-type branched-chain amino acid transport system, permease component Amino acid transport and metabolism 146319823 Common - Ketosteroid isomerase-related protein SSU05_2169 6 COG3631 COG3631, Ketosteroid isomerase-related protein General function prediction only 146318129 Common - Sortase (surface protein transpeptidase) SSU05_0475 24 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 146317829 Common - ABC-type sugar transport system, permease component SSU05_0171 147 COG0395 UgpE, ABC-type sugar transport system, permease component Carbohydrate transport and metabolism 146318990 Pathogen - Beta-fructosidases (levanase/invertase) SSU05_1336 1 COG1621 SacC, Beta-fructosidases (levanase/invertase) Carbohydrate transport and metabolism 146319276 Common - Deoxycytidylate deaminase SSU05_1622 98 COG2131 ComEB, Deoxycytidylate deaminase Nucleotide transport and metabolism 146319804 Pathogen - Predicted phosphohydrolase SSU05_2150 1 None None None 146319445 Common - Integrase SSU05_1791 55 COG4974 XerD, Site-specific recombinase XerD DNA replication, recombination, and repair 146319125 Common - UDP-N-acetylmuramyl tripeptide synthase SSU05_1471 75 COG0769 MurE, UDP-N-acetylmuramyl tripeptide synthase Cell envelope biogenesis, outer membrane 146319358 Common - Predicted phosphoesterase SSU05_1704 43 COG0622 COG0622, Predicted phosphoesterase General function prediction only 146319818 Common - NTP pyrophosphohydrolase including oxidative damage repair enzymes SSU05_2164 5 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146319650 Common - metallo cofactor biosynthesis protein SSU05_1996 95 COG0535 COG0535, Predicted Fe-S oxidoreductases General function prediction only 146319349 Common - Predicted membrane protein SSU05_1696 20 COG3601 COG3601, Predicted membrane protein Function unknown 146318507 Common - hypothetical protein SSU05_0853 6 None None None 146319346 Common - hypothetical protein SSU05_1692 25 COG4642 COG4642, Uncharacterized protein conserved in bacteria Function unknown 146319260 Common - HPr kinase/phosphorylase SSU05_1606 75 COG1493 HprK, Serine kinase of the HPr protein, regulates carbohydrate metabolism Signal transduction mechanisms 146319780 Common argS arginyl-tRNA synthetase SSU05_2126 249 COG0018 ArgS, Arginyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146318102 Common - Transcriptional regulator SSU05_0448 106 COG2188 PhnF, Transcriptional regulators Transcription 146317939 Common - ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease component SSU05_0283 249 COG4988 CydD, ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components Energy production and conversion / Posttranslational modification, protein turnover, chaperones 146319301 Common - nucleoid DNA-binding protein SSU05_1647 202 COG0776 HimA, Bacterial nucleoid DNA-binding protein DNA replication, recombination, and repair 146319421 Common - hypothetical protein SSU05_1767 40 COG3382 COG3382, Uncharacterized conserved protein Function unknown 146317801 Pathogen - hypothetical protein SSU05_0143 1 None None None 146318943 Pathogen - Glycosyltransferase SSU05_1289 1 None None None 146319468 Common secA preprotein translocase subunit SecA SSU05_1814 215 COG0653 SecA, Preprotein translocase subunit SecA (ATPase, RNA helicase) Intracellular trafficking and secretion 146319269 Common - Predicted membrane protein SSU05_1615 10 COG2246 COG2246, Predicted membrane protein Function unknown 146317780 Common - DNA-directed RNA polymerase subunit beta' SSU05_0122 249 COG0086 RpoC, DNA-directed RNA polymerase, beta' subunit/160 kD subunit Transcription 146317982 Common - hypothetical protein SSU05_0326 33 COG0657 Aes, Esterase/lipase Lipid metabolism 146317957 Pathogen - hypothetical protein SSU05_0301 1 None None None 146317962 Common - ABC-type amino acid transport system, permease component SSU05_0306 172 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146319084 Common - Large-conductance mechanosensitive channel SSU05_1430 125 COG1970 MscL, Large-conductance mechanosensitive channel Cell envelope biogenesis, outer membrane 146319115 Common - Acetyltransferase SSU05_1461 7 COG0456 RimI, Acetyltransferases General function prediction only 146318745 Common - Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain SSU05_1091 10 COG5279 CYK3, Uncharacterized protein involved in cytokinesis, contains TGc (transglutaminase/protease-like) domain Cell division and chromosome partitioning 146318818 Common - Sugar kinase, ribokinase family SSU05_1164 99 COG0524 RbsK, Sugar kinases, ribokinase family Carbohydrate transport and metabolism 146318392 Common - uridine phosphorylase SSU05_0738 14 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 146319794 Common - hypothetical protein SSU05_2140 62 COG1284 COG1284, Uncharacterized conserved protein Function unknown 146317792 Common - Adenine-specific DNA methylase SSU05_0133 10 COG0827 COG0827, Adenine-specific DNA methylase DNA replication, recombination, and repair 146317746 Common rplR 50S ribosomal protein L18 SSU05_0086 216 COG0256 RplR, Ribosomal protein L18 Translation, ribosomal structure and biogenesis 146318470 Common - hypothetical protein SSU05_0816 101 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 146318295 Common - hypothetical protein SSU05_0641 12 COG3966 DltD, Protein involved in D-alanine esterification of lipoteichoic acid and wall teichoic acid (D-alanine transfer protein) Cell envelope biogenesis, outer membrane 146318100 Common - hypothetical protein SSU05_0446 4 None None None 146318277 Common - cAMP-binding protein - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases SSU05_0623 70 COG0664 Crp, cAMP-binding proteins - catabolite gene activator and regulatory subunit of cAMP-dependent protein kinases Signal transduction mechanisms 146319003 Common - Permease of the major facilitator superfamily SSU05_1349 2 None None None 146317902 Pathogen - hypothetical protein SSU05_0246 1 None None None 146318225 Common - Cps2H SSU05_0571 8 None None None 146319727 Common - Phosphotransferase system cellobiose-specific component IIA SSU05_2073 2 COG1447 CelC, Phosphotransferase system cellobiose-specific component IIA Carbohydrate transport and metabolism 146319638 Common secE preprotein translocase subunit SecE SSU05_1984 2 COG0690 SecE, Preprotein translocase subunit SecE Intracellular trafficking and secretion 146318092 Common - Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) SSU05_0437 113 COG4098 comFA, Superfamily II DNA/RNA helicase required for DNA uptake (late competence protein) DNA replication, recombination, and repair 146318788 Common - hypothetical protein SSU05_1134 2 None None None 146317766 Common - hypothetical protein SSU05_0108 2 None None None 146318399 Common - D-alanyl-D-alanine carboxypeptidase SSU05_0745 33 COG1876 VanY, D-alanyl-D-alanine carboxypeptidase Cell envelope biogenesis, outer membrane 146319645 Common - hypothetical protein SSU05_1991 136 COG1322 COG1322, Uncharacterized protein conserved in bacteria Function unknown 146317776 Common - Tyrosyl-tRNA synthetase SSU05_0118 1 None None None 146317687 Common - Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain SSU05_0027 233 COG0046 PurL, Phosphoribosylformylglycinamidine (FGAM) synthase, synthetase domain Nucleotide transport and metabolism 146319074 Pathogen - hypothetical protein SSU05_1420 1 None None None 146319334 Common coaD phosphopantetheine adenylyltransferase SSU05_1680 208 COG0669 CoaD, Phosphopantetheine adenylyltransferase Coenzyme metabolism 146319065 Common - Predicted ATPase involved in cell division SSU05_1411 249 COG2884 FtsE, Predicted ATPase involved in cell division Cell division and chromosome partitioning 146319354 Common scpB segregation and condensation protein B SSU05_1700 152 COG1386 COG1386, Predicted transcriptional regulator containing the HTH domain Transcription 146319014 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain SSU05_1360 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146318275 Common - hypothetical protein SSU05_0621 94 COG0391 COG0391, Uncharacterized conserved protein Function unknown 146317866 Common - Transcriptional regulator/sugar kinase SSU05_0210 78 COG1940 NagC, Transcriptional regulator/sugar kinase Transcription / Carbohydrate transport and metabolism 146317921 Common - Putative effector of murein hydrolase LrgA SSU05_0265 5 COG1380 COG1380, Putative effector of murein hydrolase LrgA General function prediction only 146318887 Common - probable surface antigen negative regulator Par SSU05_1233 5 None None None 146318041 Pathogen - hypothetical protein SSU05_0386 1 None None None 146319708 Common - transketolase SSU05_2054 222 COG0021 TktA, Transketolase Carbohydrate transport and metabolism 146318999 Common - Transposase and inactivated derivative SSU05_1345 59 COG3464 COG3464, Transposase and inactivated derivatives DNA replication, recombination, and repair 146319315 Common - two-component regulator SSU05_1661 225 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146318967 Common - ribonuclease Z SSU05_1313 126 COG1234 ElaC, Metal-dependent hydrolases of the beta-lactamase superfamily III General function prediction only 146319250 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain SSU05_1596 219 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146318823 Pathogen - hypothetical protein SSU05_1169 1 None None None 146319451 Common - Acetyl-CoA carboxylase beta subunit SSU05_1797 217 COG0777 AccD, Acetyl-CoA carboxylase beta subunit Lipid metabolism 146318847 Common - hypothetical protein SSU05_1193 4 None None None 146318467 Common - Predicted sugar kinase SSU05_0814 212 COG0063 COG0063, Predicted sugar kinase Carbohydrate transport and metabolism 146318077 Common gmk guanylate kinase SSU05_0422 214 COG0194 Gmk, Guanylate kinase Nucleotide transport and metabolism 146318413 Pathogen - ABC-type phosphate transport system, ATPase component SSU05_0759 1 None None None 146319840 Common - hypothetical protein SSU05_2186 48 COG1284 COG1284, Uncharacterized conserved protein Function unknown 146318568 Common - hypothetical protein SSU05_0914 3 None None None 146319119 Pathogen - hypothetical protein SSU05_1465 1 None None None 146318751 Pathogen - hypothetical protein SSU05_1097 1 None None None 146319257 Common - Signal recognition particle GTPase SSU05_1603 1 None None None 146317986 Pathogen - hypothetical protein SSU05_0331 1 None None None 146318211 Common - gamma-glutamyl kinase SSU05_0557 189 COG0263 ProB, Glutamate 5-kinase Amino acid transport and metabolism 146319521 Common - ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component SSU05_1867 249 COG0444 DppD, ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component Amino acid transport and metabolism / Inorganic ion transport and metabolism 146319716 Common - Phosphotransferase system, galactitol-specific IIB component SSU05_2062 27 COG3414 SgaB, Phosphotransferase system, galactitol-specific IIB component Carbohydrate transport and metabolism 146318493 Common - Nucleoside diphosphate kinase SSU05_0839 230 COG0105 Ndk, Nucleoside diphosphate kinase Nucleotide transport and metabolism 146319632 Common - hypothetical protein SSU05_1978 3 None None None 146318300 Common - ABC-type Fe3+-siderophore transport system, permease component SSU05_0646 191 COG0609 FepD, ABC-type Fe3+-siderophore transport system, permease component Inorganic ion transport and metabolism 146317664 Common - DNA polymerase III subunit beta SSU05_0002 214 COG0592 DnaN, DNA polymerase sliding clamp subunit (PCNA homolog) DNA replication, recombination, and repair 146318564 Common - putative transport ATP-binding protein SSU05_0910 249 COG1131 CcmA, ABC-type multidrug transport system, ATPase component Defense mechanisms 146318425 Common - hypothetical protein SSU05_0770 213 COG0539 RpsA, Ribosomal protein S1 Translation, ribosomal structure and biogenesis 146319583 Pathogen - hypothetical protein SSU05_1929 1 None None None 146318868 Common - hyaluronidase SSU05_1214 11 None None None 146318008 Common - hypothetical protein SSU05_0353 8 None None None 146318720 Common - Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes SSU05_1066 239 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 146318140 Common - Uncharacterized conserved protein, contains S4-like domain SSU05_0486 31 COG2302 COG2302, Uncharacterized conserved protein, contains S4-like domain Function unknown 146318146 Common - ATPases with chaperone activity, ATP-binding subunit SSU05_0492 217 COG0542 ClpA, ATPases with chaperone activity, ATP-binding subunit Posttranslational modification, protein turnover, chaperones 146317977 Common - Dehydrogenase with different specificities (related to short-chain alcohol dehydrogenase) SSU05_0321 224 COG0300 DltE, Short-chain dehydrogenases of various substrate specificities General function prediction only 146318477 Common - Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) SSU05_0823 110 COG1105 FruK, Fructose-1-phosphate kinase and related fructose-6-phosphate kinase (PfkB) Carbohydrate transport and metabolism 146318729 Common - DNA gyrase subunit A SSU05_1075 230 COG0188 GyrA, Type IIA topoisomerase (DNA gyrase/topo II, topoisomerase IV), A subunit DNA replication, recombination, and repair 146318711 Common eutD phosphotransacetylase SSU05_1057 165 COG0280 Pta, Phosphotransacetylase Energy production and conversion 146318526 Common - Hypothetical cytosolic protein SSU05_0872 19 COG1196 Smc, Chromosome segregation ATPases Cell division and chromosome partitioning 146318521 Pathogen - hypothetical protein SSU05_0867 1 COG1297 COG1297, Predicted membrane protein Function unknown 146317702 Pathogen - hypothetical protein SSU05_0043 1 None None None 146319817 Common - tRNA uridine 5-carboxymethylaminomethyl modification enzyme GidA SSU05_2163 192 COG0445 GidA, NAD/FAD-utilizing enzyme apparently involved in cell division Cell division and chromosome partitioning 146318543 Pathogen - ABC-type antimicrobial peptide transport system, permease component SSU05_0889 1 None None None 146319413 Common - potassium uptake protein, Trk family SSU05_1759 89 COG0168 TrkG, Trk-type K+ transport systems, membrane components Inorganic ion transport and metabolism 146318344 Common - Formyltetrahydrofolate synthetase SSU05_0690 89 COG2759 MIS1, Formyltetrahydrofolate synthetase Nucleotide transport and metabolism 146319697 Common - putative 5-formyltetrahydrofolate cyclo-ligase SSU05_2043 146 COG0212 COG0212, 5-formyltetrahydrofolate cyclo-ligase Coenzyme metabolism 146318675 Common - Histone acetyltransferase HPA2 and related acetyltransferases SSU05_1021 20 COG0456 RimI, Acetyltransferases General function prediction only 146318237 Common - Transposase and inactivated derivative SSU05_0583 12 COG3415 COG3415, Transposase and inactivated derivatives DNA replication, recombination, and repair 146318458 Common murB UDP-N-acetylenolpyruvoylglucosamine reductase SSU05_0804 208 COG0812 MurB, UDP-N-acetylmuramate dehydrogenase Cell envelope biogenesis, outer membrane 146318032 Pathogen - hypothetical protein SSU05_0377 1 None None None 146319141 Common - ABC-type uncharacterized transport system, periplasmic component SSU05_1487 53 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 146318135 Common - cell division protein FtsZ SSU05_0481 232 COG0206 FtsZ, Cell division GTPase Cell division and chromosome partitioning 146319492 Common - Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes SSU05_1838 243 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 146318097 Common - SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase SSU05_0444 195 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 146317752 Common infA translation initiation factor IF-1 SSU05_0092 214 COG0361 InfA, Translation initiation factor 1 (IF-1) Translation, ribosomal structure and biogenesis 146318596 Common - hypothetical protein SSU05_0942 3 None None None 146319249 Common - Signal transduction histidine kinase SSU05_1595 216 COG0642 BaeS, Signal transduction histidine kinase Signal transduction mechanisms 146318384 Common - Uncharacterized NAD(FAD)-dependent dehydrogenase SSU05_0730 246 COG0446 HcaD, Uncharacterized NAD(FAD)-dependent dehydrogenases General function prediction only 146319110 Common - hypothetical protein SSU05_1456 39 COG2268 COG2268, Uncharacterized protein conserved in bacteria Function unknown 146319215 Common - Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities SSU05_1561 231 COG1168 MalY, Bifunctional PLP-dependent enzyme with beta-cystathionase and maltose regulon repressor activities Amino acid transport and metabolism 146319233 Common - Ammonia permease SSU05_1579 3 COG4720 COG4720, Predicted membrane protein Function unknown 146319440 Common - Restriction endonuclease S subunit SSU05_1786 53 COG0732 HsdS, Restriction endonuclease S subunits Defense mechanisms 146319545 Common - Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase SSU05_1891 28 COG4632 EpsL, Exopolysaccharide biosynthesis protein related to N-acetylglucosamine-1-phosphodiester alpha-N-acetylglucosaminidase Carbohydrate transport and metabolism 146318680 Common - ABC-type amino acid transport/signal transduction system, periplasmic component/domain SSU05_1026 144 COG0834 HisJ, ABC-type amino acid transport/signal transduction systems, periplasmic component/domain Amino acid transport and metabolism / Signal transduction mechanisms 146319092 Common - Acyl-ACP thioesterase SSU05_1438 11 COG3884 FatA, Acyl-ACP thioesterase Lipid metabolism 146318455 Common - Predicted xylanase/chitin deacetylase SSU05_0802 92 COG0726 CDA1, Predicted xylanase/chitin deacetylase Carbohydrate transport and metabolism 146318353 Pathogen - hypothetical protein SSU05_0699 1 None None None 146317671 Common - Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit SSU05_0009 45 COG1188 COG1188, Ribosome-associated heat shock protein implicated in the recycling of the 50S subunit (S4 paralog) Translation, ribosomal structure and biogenesis 146318462 Common - Spermidine/putrescine-binding periplasmic protein SSU05_0808 136 COG0687 PotD, Spermidine/putrescine-binding periplasmic protein Amino acid transport and metabolism 146318575 Pathogen - hypothetical protein SSU05_0921 1 None None None 146318039 Common - putative ATP-binding protein SSU05_0383 31 COG0433 COG0433, Predicted ATPase General function prediction only 146319242 Common - hypothetical protein SSU05_1588 5 None None None 146319128 Common - hypothetical protein SSU05_1474 25 COG1476 COG1476, Predicted transcriptional regulators Transcription 146319273 Common - UDP-N-acetylglucosamine 1-carboxyvinyltransferase SSU05_1619 219 COG0766 MurA, UDP-N-acetylglucosamine enolpyruvyl transferase Cell envelope biogenesis, outer membrane 146318440 Common - YlyB SSU05_0786 215 COG0564 RluA, Pseudouridylate synthases, 23S RNA-specific Translation, ribosomal structure and biogenesis 146318558 Common - hypothetical protein SSU05_0904 2 None None None 146318904 Common - phospho-2-dehydro-3-heoxyheptonate aldolase SSU05_1250 108 COG0722 AroG, 3-deoxy-D-arabino-heptulosonate 7-phosphate (DAHP) synthase Amino acid transport and metabolism 146319747 Common - D-tyrosyl-tRNA deacylase SSU05_2093 139 COG1490 Dtd, D-Tyr-tRNAtyr deacylase Translation, ribosomal structure and biogenesis 146319059 Common - putative ABC transporter SSU05_1405 249 COG1132 MdlB, ABC-type multidrug transport system, ATPase and permease components Defense mechanisms 146319773 Common - hypothetical protein SSU05_2119 3 None None None 146319386 Common - Response regulator SSU05_1732 204 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146319642 Common - purine operon repressor SSU05_1988 110 COG0503 Apt, Adenine/guanine phosphoribosyltransferases and related PRPP-binding proteins Nucleotide transport and metabolism 146318807 Common - Beta-glucosidase-related glycosidase SSU05_1153 175 COG1472 BglX, Beta-glucosidase-related glycosidases Carbohydrate transport and metabolism 146317824 Common - O-sialoglycoprotein endopeptidase SSU05_0166 249 COG0533 QRI7, Metal-dependent proteases with possible chaperone activity Posttranslational modification, protein turnover, chaperones 146318309 Common - hypothetical protein SSU05_0655 127 COG2524 COG2524, Predicted transcriptional regulator, contains C-terminal CBS domains Transcription 146318911 Common - ABC transporter permease protein SSU05_1257 50 COG2984 COG2984, ABC-type uncharacterized transport system, periplasmic component General function prediction only 146318687 Common - O-acetylhomoserine sulfhydrylase SSU05_1033 209 COG2873 MET17, O-acetylhomoserine sulfhydrylase Amino acid transport and metabolism 146319188 Common - putative flavodoxin SSU05_1534 81 COG0716 FldA, Flavodoxins Energy production and conversion 146319266 Common - Transcriptional accessory protein SSU05_1612 143 COG2183 Tex, Transcriptional accessory protein Transcription 146319826 Common - L-serine deaminase SSU05_2172 124 COG1760 SdaA, L-serine deaminase Amino acid transport and metabolism 146319471 Common - Phosphotransferase system IIC component, glucose/maltose/N-acetylglucosamine-specific SSU05_1817 60 COG1263 PtsG, Phosphotransferase system IIC components, glucose/maltose/N-acetylglucosamine-specific Carbohydrate transport and metabolism 146319288 Common - Superfamily II DNA and RNA helicase SSU05_1634 231 COG0513 SrmB, Superfamily II DNA and RNA helicases DNA replication, recombination, and repair / Transcription / Translation, ribosomal structure and biogenesis 146317680 Common - hypothetical protein SSU05_0020 12 COG3883 COG3883, Uncharacterized protein conserved in bacteria Function unknown 146318863 Common nrdF ribonucleotide-diphosphate reductase subunit beta SSU05_1209 148 COG0208 NrdF, Ribonucleotide reductase, beta subunit Nucleotide transport and metabolism 146318916 Common - chorismate synthase SSU05_1262 227 COG0082 AroC, Chorismate synthase Amino acid transport and metabolism 146319099 Common - Purine-nucleoside phosphorylase SSU05_1445 99 COG0813 DeoD, Purine-nucleoside phosphorylase Nucleotide transport and metabolism 146319504 Common - hypothetical protein SSU05_1850 150 COG0779 COG0779, Uncharacterized protein conserved in bacteria Function unknown 146317773 Common - Copper chaperone SSU05_0115 5 COG2608 CopZ, Copper chaperone Inorganic ion transport and metabolism 146319660 Pathogen - hypothetical protein SSU05_2006 1 None None None 146318197 Common - 6-phosphofructokinase SSU05_0543 160 COG0205 PfkA, 6-phosphofructokinase Carbohydrate transport and metabolism 146318662 Common - hypothetical protein SSU05_1008 14 COG0221 Ppa, Inorganic pyrophosphatase Energy production and conversion 146318158 Pathogen - hypothetical protein SSU05_0504 1 None None None 146319722 Common - ABC-type amino acid transport system, permease component SSU05_2068 176 COG0765 HisM, ABC-type amino acid transport system, permease component Amino acid transport and metabolism 146317717 Pathogen - hypothetical protein SSU05_0057 1 None None None 146318858 Common - methylcitrate synthase SSU05_1204 194 COG0372 GltA, Citrate synthase Energy production and conversion 146318328 Common - hypothetical protein SSU05_0673 7 None None None 146318430 Common - Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes SSU05_0776 236 COG1104 NifS, Cysteine sulfinate desulfinase/cysteine desulfurase and related enzymes Amino acid transport and metabolism 146319307 Common - Predicted rRNA methylase SSU05_1653 131 COG1189 COG1189, Predicted rRNA methylase Translation, ribosomal structure and biogenesis 146319403 Pathogen - Permease of the major facilitator superfamily SSU05_1749 1 None None None 146318286 Common - S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) SSU05_0632 183 COG0809 QueA, S-adenosylmethionine:tRNA-ribosyltransferase-isomerase (queuine synthetase) Translation, ribosomal structure and biogenesis 146318791 Common - hypothetical protein SSU05_1137 36 COG2966 COG2966, Uncharacterized conserved protein Function unknown 146319595 Common - Acetyltransferase SSU05_1941 5 COG0456 RimI, Acetyltransferases General function prediction only 146318257 Common - SAM-dependent methyltransferase related to tRNA (uracil-5-)-methyltransferase SSU05_0603 201 COG2265 TrmA, SAM-dependent methyltransferases related to tRNA (uracil-5-)-methyltransferase Translation, ribosomal structure and biogenesis 146318603 Pathogen - lantibiotic modifying enzyme SSU05_0949 1 COG4403 LcnDR2, Lantibiotic modifying enzyme Defense mechanisms 146318205 Common - ABC-type polar amino acid transport system, ATPase component SSU05_0551 249 COG1126 GlnQ, ABC-type polar amino acid transport system, ATPase component Amino acid transport and metabolism 146318650 Common rnhB ribonuclease HII SSU05_0996 209 COG0164 RnhB, Ribonuclease HII DNA replication, recombination, and repair 146319447 Common - hypothetical protein SSU05_1793 1 None None None 146318400 Common - hypothetical protein SSU05_0746 63 COG2764 PhnB, Uncharacterized protein conserved in bacteria Function unknown 146319157 Pathogen - hypothetical protein SSU05_1502 1 None None None 146317952 Common - hypothetical protein SSU05_0296 48 COG2848 COG2848, Uncharacterized conserved protein Function unknown 146318485 Pathogen - hypothetical protein SSU05_0831 1 None None None 146318706 Common - A/G-specific DNA glycosylase SSU05_1052 209 COG1194 MutY, A/G-specific DNA glycosylase DNA replication, recombination, and repair 146318113 Common valS valyl-tRNA synthetase SSU05_0459 249 COG0525 ValS, Valyl-tRNA synthetase Translation, ribosomal structure and biogenesis 146319434 Common - mannose-specific PTS IID SSU05_1780 41 COG3716 ManZ, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IID Carbohydrate transport and metabolism 146318253 Common aroK shikimate kinase SSU05_0599 197 COG0703 AroK, Shikimate kinase Amino acid transport and metabolism 146319551 Common - 30S ribosomal protein S9 SSU05_1897 215 COG0103 RpsI, Ribosomal protein S9 Translation, ribosomal structure and biogenesis 146319750 Common - sortase-like protein SSU05_2096 18 COG3764 SrtA, Sortase (surface protein transpeptidase) Cell envelope biogenesis, outer membrane 146319738 Common - Mn2+/Zn2+ ABC transporter permease SSU05_2084 170 COG1108 ZnuB, ABC-type Mn2+/Zn2+ transport systems, permease components Inorganic ion transport and metabolism 146319426 Pathogen - hypothetical protein SSU05_1772 1 None None None 146319368 Common - Acylphosphatase SSU05_1714 20 COG1254 AcyP, Acylphosphatases Energy production and conversion 146317675 Common - Predicted ATPase of the PP-loop superfamily implicated in cell cycle control SSU05_0013 210 COG0037 MesJ, Predicted ATPase of the PP-loop superfamily implicated in cell cycle control Cell division and chromosome partitioning 146318375 Common - hypothetical protein SSU05_0721 5 COG3711 BglG, Transcriptional antiterminator Transcription 146318235 Common - CMP-N-acetylneuraminic acid synthetase SSU05_0581 79 COG1083 NeuA, CMP-N-acetylneuraminic acid synthetase Cell envelope biogenesis, outer membrane 146319789 Common - ABC-type maltose transport system, permease component SSU05_2135 155 COG3833 MalG, ABC-type maltose transport systems, permease component Carbohydrate transport and metabolism 146318956 Common - Predicted divalent heavy-metal cations transporter SSU05_1302 100 COG0428 COG0428, Predicted divalent heavy-metal cations transporter Inorganic ion transport and metabolism 146317885 Common - LysM repeat protein SSU05_0229 7 None None None 146319730 Common - Transcriptional antiterminator SSU05_2076 31 COG3711 BglG, Transcriptional antiterminator Transcription 146319759 Pathogen - Uncharacterized membrane protein, possible Na+ channel or pump SSU05_2105 1 None None None 146319603 Common - Isopropylmalate/homocitrate/citramalate synthase SSU05_1949 214 COG0119 LeuA, Isopropylmalate/homocitrate/citramalate synthases Amino acid transport and metabolism 146319153 Common - Predicted hydrolase (HAD superfamily) SSU05_1499 116 COG1011 COG1011, Predicted hydrolase (HAD superfamily) General function prediction only 146318715 Common - hypothetical protein SSU05_1061 9 COG4116 COG4116, Uncharacterized protein conserved in bacteria Function unknown 146319608 Common polC DNA polymerase III PolC SSU05_1954 211 COG2176 PolC, DNA polymerase III, alpha subunit (gram-positive type) DNA replication, recombination, and repair 146319499 Common - Ribosome-binding factor A SSU05_1845 158 COG0858 RbfA, Ribosome-binding factor A Translation, ribosomal structure and biogenesis 146318983 Common - Glutathione S-transferase SSU05_1329 96 COG0625 Gst, Glutathione S-transferase Posttranslational modification, protein turnover, chaperones 146319579 Common - Uridine phosphorylase SSU05_1925 39 COG2820 Udp, Uridine phosphorylase Nucleotide transport and metabolism 146318176 Common - Predicted membrane protein SSU05_0522 43 COG2035 COG2035, Predicted membrane protein Function unknown 146319391 Common - hypothetical protein SSU05_1737 249 COG0492 TrxB, Thioredoxin reductase Posttranslational modification, protein turnover, chaperones 146319768 Common - Organic radical activating enzyme SSU05_2114 65 COG0602 NrdG, Organic radical activating enzymes Posttranslational modification, protein turnover, chaperones 146319609 Common - Dihydroxyacetone kinase SSU05_1955 77 COG2376 DAK1, Dihydroxyacetone kinase Carbohydrate transport and metabolism 146319688 Common - Fructose-2,6-bisphosphatase SSU05_2034 3 COG0406 GpmB, Fructose-2,6-bisphosphatase Carbohydrate transport and metabolism 146318243 Common - Transposase and inactivated derivative, IS30 family SSU05_0589 62 COG2826 Tra8, Transposase and inactivated derivatives, IS30 family DNA replication, recombination, and repair 146319490 Common - lipoate-protein ligase SSU05_1836 83 COG0095 LplA, Lipoate-protein ligase A Coenzyme metabolism 146319102 Common - phosphopentomutase SSU05_1448 71 COG1015 DeoB, Phosphopentomutase Carbohydrate transport and metabolism 146319512 Common - Transcriptional regulator SSU05_1858 62 COG1316 LytR, Transcriptional regulator Transcription 146319316 Pathogen - hypothetical protein SSU05_1662 4 None None None 146318766 Common - Kef-type K+ transport system, predicted NAD-binding component SSU05_1112 92 COG1226 Kch, Kef-type K+ transport systems, predicted NAD-binding component Inorganic ion transport and metabolism 146319479 Common - aminopeptidase P; XAA-pro aminopeptidase SSU05_1825 248 COG0006 PepP, Xaa-Pro aminopeptidase Amino acid transport and metabolism 146319694 Common gpsA NAD(P)H-dependent glycerol-3-phosphate dehydrogenase SSU05_2040 212 COG0240 GpsA, Glycerol-3-phosphate dehydrogenase Energy production and conversion 146318207 Pathogen - hypothetical protein SSU05_0553 1 None None None 146319833 Common - Predicted Zn-dependent peptidase SSU05_2179 131 COG0612 PqqL, Predicted Zn-dependent peptidases General function prediction only 146319344 Common - MF3-like protein SSU05_1690 13 COG3237 COG3237, Uncharacterized protein conserved in bacteria Function unknown 146319681 Common gltX glutamyl-tRNA synthetase SSU05_2027 246 COG0008 GlnS, Glutamyl- and glutaminyl-tRNA synthetases Translation, ribosomal structure and biogenesis 146317693 Common - phosphoribosylamine--glycine ligase SSU05_0033 231 COG0151 PurD, Phosphoribosylamine-glycine ligase Nucleotide transport and metabolism 146318770 Pathogen - hypothetical protein SSU05_1116 1 None None None 146318185 Common tpiA triosephosphate isomerase SSU05_0531 216 COG0149 TpiA, Triosephosphate isomerase Carbohydrate transport and metabolism 146318200 Common - Glycine/D-amino acid oxidases (deaminating) SSU05_0546 90 COG0665 DadA, Glycine/D-amino acid oxidases (deaminating) Amino acid transport and metabolism 146318515 Common - 5-methylcytosine-specific restriction enzyme subunit McrC SSU05_0861 21 COG4268 McrC, McrBC 5-methylcytosine restriction system component Defense mechanisms 146319297 Common - Transposase and inactivated derivative SSU05_1643 90 COG3547 COG3547, Transposase and inactivated derivatives DNA replication, recombination, and repair 146317782 Common - hypothetical protein SSU05_0124 6 COG1619 LdcA, Uncharacterized proteins, homologs of microcin C7 resistance protein MccF Defense mechanisms 146318853 Common - hypothetical protein SSU05_1199 7 COG4868 COG4868, Uncharacterized protein conserved in bacteria Function unknown 146318182 Common - DNA-directed RNA polymerase specialized sigma subunit SSU05_0528 102 COG1595 RpoE, DNA-directed RNA polymerase specialized sigma subunit, sigma24 homolog Transcription 146318509 Common - Short-chain alcohol dehydrogenase of unknown specificity SSU05_0855 234 COG4221 COG4221, Short-chain alcohol dehydrogenase of unknown specificity General function prediction only 146318588 Common - DNA helicase SSU05_0934 224 COG0210 UvrD, Superfamily I DNA and RNA helicases DNA replication, recombination, and repair 146317954 Common hrcA heat-inducible transcription repressor SSU05_0298 147 COG1420 HrcA, Transcriptional regulator of heat shock gene Transcription 146319031 Pathogen - Glucose-6-phosphate isomerase SSU05_1377 1 None None None 146317941 Common - hypothetical protein SSU05_0285 11 None None None 146318610 Common - hypothetical protein SSU05_0956 179 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146319483 Common - Mg2+ and Co2+ transporter SSU05_1829 8 COG0598 CorA, Mg2+ and Co2+ transporters Inorganic ion transport and metabolism 146319463 Common - enoyl-CoA hydratase SSU05_1809 166 COG1024 CaiD, Enoyl-CoA hydratase/carnithine racemase Lipid metabolism 146317700 Pathogen - hypothetical protein SSU05_0040 1 None None None 146319821 Common - hypothetical protein SSU05_2167 32 COG1051 COG1051, ADP-ribose pyrophosphatase Nucleotide transport and metabolism 146319034 Common - ABC-type antimicrobial peptide transport system, permease component SSU05_1380 48 COG4591 LolE, ABC-type transport system, involved in lipoprotein release, permease component Cell envelope biogenesis, outer membrane 146318624 Pathogen - hypothetical protein SSU05_0970 1 None None None 146318266 Common - hypothetical protein SSU05_0612 8 COG5353 COG5353, Uncharacterized protein conserved in bacteria Function unknown 146317972 Common - hypothetical protein SSU05_0315 25 COG3506 COG3506, Uncharacterized conserved protein Function unknown 146317721 Common - 3-methyladenine DNA glycosylase SSU05_0061 132 COG2818 Tag, 3-methyladenine DNA glycosylase DNA replication, recombination, and repair 146319361 Common - hypothetical protein SSU05_1707 13 COG3763 COG3763, Uncharacterized protein conserved in bacteria Function unknown 146319292 Common - Phosphoglycerate mutase 1 SSU05_1638 121 COG0588 GpmA, Phosphoglycerate mutase 1 Carbohydrate transport and metabolism 146318895 Pathogen - hypothetical protein SSU05_1241 1 None None None 146318015 Common - galactokinase SSU05_0360 86 COG0153 GalK, Galactokinase Carbohydrate transport and metabolism 146318074 Common - hypothetical protein SSU05_0419 3 None None None 146319052 Common - diacylglycerol kinase SSU05_1398 71 COG0818 DgkA, Diacylglycerol kinase Cell envelope biogenesis, outer membrane 146318020 Common - Predicted hydrolase of the HAD superfamily SSU05_0365 43 COG2179 COG2179, Predicted hydrolase of the HAD superfamily General function prediction only 146318743 Common rpsT 30S ribosomal protein S20 SSU05_1089 146 COG0268 RpsT, Ribosomal protein S20 Translation, ribosomal structure and biogenesis 146318293 Common - Predicted membrane protein involved in D-alanine export SSU05_0639 85 COG1696 DltB, Predicted membrane protein involved in D-alanine export Cell envelope biogenesis, outer membrane 146319303 Common - Lysophospholipase L1 and related esterases SSU05_1649 18 COG2755 TesA, Lysophospholipase L1 and related esterases Amino acid transport and metabolism 146317984 Common tig trigger factor SSU05_0328 209 COG0544 Tig, FKBP-type peptidyl-prolyl cis-trans isomerase (trigger factor) Posttranslational modification, protein turnover, chaperones 146319415 Common - DinF SSU05_1761 179 COG0534 NorM, Na+-driven multidrug efflux pump Defense mechanisms 146319466 Common alr alanine racemase SSU05_1812 200 COG0787 Alr, Alanine racemase Cell envelope biogenesis, outer membrane 146318393 Common - hypothetical protein SSU05_0739 18 None None None 146319523 Common - hypothetical protein SSU05_1869 2 None None None 146318500 Common - Thymidine kinase SSU05_0846 62 COG1435 Tdk, Thymidine kinase Nucleotide transport and metabolism 146319395 Common mraY phospho-N-acetylmuramoyl-pentapeptide-transferase SSU05_1741 229 COG0472 Rfe, UDP-N-acetylmuramyl pentapeptide phosphotransferase/UDP-N- acetylglucosamine-1-phosphate transferase Cell envelope biogenesis, outer membrane 146317852 Pathogen - hypothetical protein SSU05_0196 4 COG5373 COG5373, Predicted membrane protein Function unknown 146317933 Common rpmF 50S ribosomal protein L32 SSU05_0277 55 COG0333 RpmF, Ribosomal protein L32 Translation, ribosomal structure and biogenesis 146319432 Common - putative PTS system, mannose-specific component IIAB SSU05_1778 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 146319086 Common - UDP-glucose 4-epimerase SSU05_1432 229 COG1087 GalE, UDP-glucose 4-epimerase Cell envelope biogenesis, outer membrane 146319324 Common - SAM-dependent methyltransferase SSU05_1670 29 COG2226 UbiE, Methylase involved in ubiquinone/menaquinone biosynthesis Coenzyme metabolism 146319803 Common - two-component sensor histidine kinase SSU05_2149 11 COG2972 COG2972, Predicted signal transduction protein with a C-terminal ATPase domain Signal transduction mechanisms 146317964 Pathogen - hypothetical protein SSU05_0308 1 None None None 146319383 Common - Replication initiation/membrane attachment protein SSU05_1729 7 COG3611 DnaB, Replication initiation/membrane attachment protein DNA replication, recombination, and repair 146318667 Common - ADP-glucose pyrophosphorylase SSU05_1013 223 COG0448 GlgC, ADP-glucose pyrophosphorylase Carbohydrate transport and metabolism 146319633 Common tsf elongation factor Ts SSU05_1979 216 COG0264 Tsf, Translation elongation factor Ts Translation, ribosomal structure and biogenesis 146317936 Common - NAD-dependent aldehyde dehydrogenase SSU05_0280 187 COG1454 EutG, Alcohol dehydrogenase, class IV Energy production and conversion 146319177 Pathogen - hypothetical protein SSU05_1523 1 None None None 146318166 Common - glutathione reductase SSU05_0512 156 COG1249 Lpd, Pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (E3) component, and related enzymes Energy production and conversion 146318866 Pathogen - hyaluronidase SSU05_1212 2 None None None 146318539 Common - Response regulator consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain SSU05_0885 24 COG0745 OmpR, Response regulators consisting of a CheY-like receiver domain and a winged-helix DNA-binding domain Signal transduction mechanisms / Transcription 146318126 Pathogen - Ribonucleases G and E SSU05_0472 1 None None None 146317871 Pathogen - hypothetical protein SSU05_0215 1 None None None 146317843 Common - Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase SSU05_0185 97 COG2723 BglB, Beta-glucosidase/6-phospho-beta-glucosidase/beta- galactosidase Carbohydrate transport and metabolism 146319198 Common - ABC-type branched-chain amino acid transport system, ATPase component SSU05_1544 249 COG0411 LivG, ABC-type branched-chain amino acid transport systems, ATPase component Amino acid transport and metabolism 146317836 Common - Epf-like protein SSU05_0178 3 None None None 146318087 Common - Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain SSU05_0432 216 COG2197 CitB, Response regulator containing a CheY-like receiver domain and an HTH DNA-binding domain Signal transduction mechanisms / Transcription 146317764 Pathogen - hypothetical protein SSU05_0106 1 None None None 146318735 Common - ABC-type uncharacterized transport system, ATPase component SSU05_1081 249 COG3845 COG3845, ABC-type uncharacterized transport systems, ATPase components General function prediction only 146318876 Common - keto-hydroxyglutarate-aldolase/keto-deoxy-phosphogluconate aldolase SSU05_1222 126 COG0800 Eda, 2-keto-3-deoxy-6-phosphogluconate aldolase Carbohydrate transport and metabolism 146318381 Common - hypothetical protein SSU05_0727 3 COG0400 COG0400, Predicted esterase General function prediction only 146317737 Common rpsC 30S ribosomal protein S3 SSU05_0077 249 COG0092 RpsC, Ribosomal protein S3 Translation, ribosomal structure and biogenesis 146319675 Common - hypothetical protein SSU05_2021 72 COG3865 COG3865, Uncharacterized protein conserved in bacteria Function unknown 146318962 Common - hypothetical protein SSU05_1308 4 None None None 146318001 Common - Predicted hydrolase of the HAD superfamily SSU05_0346 114 COG0561 Cof, Predicted hydrolases of the HAD superfamily General function prediction only 146317778 Common - Membrane carboxypeptidase (penicillin-binding protein) SSU05_0120 200 COG0744 MrcB, Membrane carboxypeptidase (penicillin-binding protein) Cell envelope biogenesis, outer membrane 146317918 Pathogen - hypothetical protein SSU05_0262 1 None None None 146318984 Pathogen - hypothetical protein SSU05_1330 1 None None None 146317803 Common - single-strand DNA-binding protein SSU05_0145 201 COG0629 Ssb, Single-stranded DNA-binding protein DNA replication, recombination, and repair 146319173 Pathogen - hypothetical protein SSU05_1519 2 None None None 146318944 Common - Glycosyltransferase SSU05_1290 23 COG0438 RfaG, Glycosyltransferase Cell envelope biogenesis, outer membrane 146319352 Common - hypothetical protein SSU05_1698 119 COG0219 CspR, Predicted rRNA methylase (SpoU class) Translation, ribosomal structure and biogenesis 146318630 Pathogen - hypothetical protein SSU05_0976 1 None None None 146317813 Common - glyceraldehyde-3-phosphate dehydrogenase SSU05_0155 217 COG0057 GapA, Glyceraldehyde-3-phosphate dehydrogenase/erythrose-4-phosphate dehydrogenase Carbohydrate transport and metabolism 146317853 Common - x-prolyl-dipeptidyl aminopeptidase SSU05_0197 12 COG2936 COG2936, Predicted acyl esterases General function prediction only 146319376 Common - Superfamily II DNA/RNA helicase, SNF2 family SSU05_1722 131 COG0553 HepA, Superfamily II DNA/RNA helicases, SNF2 family Transcription / DNA replication, recombination, and repair 146318029 Common - Uncharacterized plant Iojap protein-like protein SSU05_0374 186 COG0799 COG0799, Uncharacterized homolog of plant Iojap protein Function unknown 146318821 Common - hypothetical protein SSU05_1167 43 COG2211 MelB, Na+/melibiose symporter and related transporters Carbohydrate transport and metabolism 146318337 Common - putative modification enzyme of type III restriction-modification system SSU05_0683 74 COG2189 COG2189, Adenine specific DNA methylase Mod DNA replication, recombination, and repair 146318925 Common cmk cytidylate kinase SSU05_1271 204 COG0283 Cmk, Cytidylate kinase Nucleotide transport and metabolism 146318997 Common - Lactoylglutathione lyase and related lyases SSU05_1343 8 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism 146318104 Common - Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB SSU05_0450 41 COG3444 COG3444, Phosphotransferase system, mannose/fructose/N-acetylgalactosamine-specific component IIB Carbohydrate transport and metabolism 146318988 Common - Lactoylglutathione lyase and related lyases SSU05_1334 45 COG0346 GloA, Lactoylglutathione lyase and related lyases Amino acid transport and metabolism